| Document | Document Title |
|---|---|
| US08400358B2 |
Method to modify calibration data used to locate a mobile unit
A method of modifying calibration data used to geo-locate a mobile station located in an indoor environment is disclosed. When a mobile station is located indoors, the signal strength of signals received and/or transmitted by the mobile station have the tendency to be lower than the strength of the signals received by a mobile station located outdoors. As a result of these lower signal strengths, geo-location efforts which rely on signal strengths may result in unsatisfactory location accuracy. Modifying pre-existing calibration data obtained outdoors may provide a way to simulate indoor calibration data characteristics. |
| US08400356B2 |
Directive spatial interference beam control
The invention, in its various aspects and embodiments, comprises a variety methods and apparatuses. The methods variously determine the delay (or phase shift) in each element of a phased array to simultaneously form, steer and/or combine a set of beam shapes. The apparatuses include apparatuses that implement the methods as well as apparatuses that employ such methods. The invention also includes a beam controlled by such methods. |
| US08400355B1 |
Passive photonic dense wavelength-division multiplexing true-time-delay system
A photonic true time delay system for steering one or more radio frequency beams from an electronically scanned array antenna incorporates passive optical true time delay modules for the entire array based upon dense-wavelength-division multiplexed encoding of optical time delays. In addition, electronic selection of time delays allows for elimination of optical filter tuning and optical switching, and can function in either or both transmit and receive modes of the antenna array. |
| US08400353B2 |
Apparatus and method for use in global position measurements
Apparatus and methods are provided for use in a receiver that receives global positioning data from one or more satellites above the Earth's surface. The apparatus and methods involve detecting a change in at least one parameter associated with the receiver and determining if the change in the at least one parameter is to be treated as erroneous. As a result of determining if the change in the at least one parameter is to be treated as erroneous, a further action may be performed. Determining if the change is to be treated as erroneous may include, for example, detecting changes in more than one parameter and determining if the changes are coincident. Detecting a change in at least one parameter may also enable the receiver to predict the presence and magnitude of multipath components of signals, predict changes in an environment local to the receiver, predict large errors in position estimates determined by the receiver and modify an acquisition and tracking strategy used by the receiver. |
| US08400346B2 |
Method and apparatus for locating a golf ball with doppler radar
A method comprises transmitting a radar signal into an target area, receiving reflected portions of the radar signal from the target area, and processing the reflected portions of the radar signal. The step of processing comprises windowing analog signals representative of the reflected portions of the radar signal, performing a fast Fourier transform on the windowed analog signals to produce an FFT result for each window, and obtaining the average of the FFT results from consecutive windows. In accordance with the method, a user receives indication from an indicator that a golf ball is present in the target area when the average of the FFT results corresponds to characteristics of the golf ball. The system comprises a radar transceiver, a processor for processing reflected portions of the radar signal, and an indicator indicating to the user a golf ball present in the target area. |
| US08400343B1 |
Pipeline analog to digital converter with split-path level shifting technique
A stage of a pipeline analog-to-digital converter (ADC) is provided according to embodiments of the present invention. The stage of the present invention has double-amplifier architecture and uses level-shifting technique to generate a residue of the stage. The amplifiers of the stage are implemented in two different split paths, thereby to generate a relatively coarse amplification result and a relative fine amplification result. The relatively coarse amplification result is used to level-shift the output level of the amplifier. As a result, the stage of the present invention can have a correct residual by using amplifiers of moderate quality. |
| US08400342B2 |
Explosion proof electro-mechanical joystick
A joystick comprising a housing, a ball supported and held within the housing, and a joystick handle attached to the ball. The joystick also includes a first device held within the housing, and a second device held within the housing. The joystick also includes a first engagement shaft extending from the first device to the ball, the first engagement shaft having an end adjacent the ball and engaging the ball, and a second engagement shaft extending from the second device to the ball, the second engagement shaft having an end adjacent the ball and engaging the ball. |
| US08400340B2 |
Achieving high dynamic range in a sigma delta analog to digital converter
A continuous-time sigma-delta analog to digital converter (CTSD ADC) includes a comparator that samples the time integral of an analog signal at each rising edge and falling edge of a sampling clock. A feedback block, operating as a digital to analog converter, receives the outputs of the comparator and generates corresponding analog signals also at each rising and falling edge of the sampling clock. The feedback blocks are implemented as either switched-resistor or switched-current circuits. High signal-to-noise ratio (SNR) is achieved in the CTSD ADC without the need to use very high sampling clock frequencies. Compensation for excess loop delay is provided using a local feedback technique. In an embodiment, the sigma delta modulator in the CTSD ADC is implemented as a second order loop, and the comparator as a two-level comparator. |
| US08400336B2 |
Methods and devices for reordered parallel entropy coding and decoding
A method for parallel context modeling through reordering the bits of an input sequence to form groups of bits in accordance with a context model-specific reordering schedule. The reordering schedule is developed such that the groups of bits are formed to satisfy two conditions: first, that the context for each of the bits in a group of bits is different from the context of each of the other bits in that group, and the context of each of the bits in that group is determined independently from each of the other bits in that group. The parallel context modeling may be used in encoding or decoding operations. |
| US08400334B2 |
Asymmetric dictionary-based compression/decompression useful for broadcast or multicast unidirectional communication channels
An asymmetric approach for compressing digital data, or digitized analog data, uses dictionary-based compression for a transmitter and receiver communicating over a lossy unidirectional communication channel. The transmitter is responsible for generating active dictionaries, selecting appropriate dictionaries for compressing data, retiring old dictionaries, and sending new dictionaries to the receiver. The receiver passively stores the dictionaries from the transmitter and uses the right stored dictionary to decompress data received from the transmitter, as indicated by instructions in the compressed data set. |
| US08400329B2 |
Image display apparatus for vehicle
According to one embodiment, an imaging unit inputs a camera image of surroundings of a vehicle. The surroundings include at least one of a front side and a back side of the vehicle. A first image generation unit generates a mask image to conceal a protection region of personal information included in a region of a first vehicle on the camera image. The first vehicle exists at the front side or the back side of the user's vehicle. A surroundings-monitoring unit decides whether a second vehicle exists at a front side or a back side of the first vehicle by monitoring the camera image. A second image generation unit generates an identification image of the second vehicle when the second vehicle exists. A processing unit generates a composite image by combining the mask image and the identification image with the camera image, and displays the composite image to present to a user of the vehicle. |
| US08400328B2 |
Brake warning device
A device and method for providing a warning to an operator of a truck/tractor and trailer unit of a potential loss or reduction of brakes. The invention provides a pressure differential sensor (12) which bridges between an air supply line (13, 16) to the spring brakes (17) of a truck/tractor and an air supply line (14) to the trailer. An audible and/or visual warning device (31, 33) coupled to the sensor (12) is activated upon a differential between the pressures in the respective supply lines (13, 16 and 14) being sensed. |
| US08400327B2 |
Method for querying a measurement value
A method for querying a measurement value, wherein the measurement value is converted into a modulation signal that influences the reflective properties of a sensor antenna. A signal is emitted via a query device, wherein the signal is returned in an altered fashion by the sensor antenna and then received again by the query device. The measurement value is determined from the altered signal received. According to at least one embodiment of the invention, a plurality of measurement values are detected by sensors and the query device is moved past a plurality of sensor antennas in a vehicle or by a person. Thus, a plurality of sensors detect measurement values on a railroad line, for example. The vehicle is, for example, a rail vehicle traveling on the track of the railroad line. |
| US08400326B2 |
Instrumentation of appraisal well for telemetry
A telemetry system for use in developing a field of wells has a first downhole device capable of transmitting and/or receiving signals disposed in an appraisal well, an electronics control system located at or near the top of the appraisal, a cable disposed in the appraisal well that provides signal communication between the first downhole device and the electronics control system, and a second downhole device capable of transmitting and/or receiving signals disposed in a second wellbore. The signal is passed through the cable between the first downhole device and the electronics control system. From there, the signal may be re-transmitted to a desired location. |
| US08400322B2 |
Apparatus, system, and method for scalable media output
An apparatus, system, and method are disclosed for scalable media output. The apparatus includes a proximity sensor module to detect the presence and proximity of a user, and to generate presence and proximity data in response to the location of the user with respect to the proximity sensor module. The sensor control module is configured to scale the media output of a media device. The system includes the apparatus and a display module configured to output visual information and an audio module configured to output aural information. The method includes detecting the presence and proximity of a user, generating presence and proximity data in response to the location of the user with respect to a proximity sensor module, communicating the presence and proximity data with a sensor control module, and scaling the media output of a media device in response to the presence and proximity data. |
| US08400316B2 |
Electronic thermometer
An electronic thermometer has a probe having a temperature measuring unit at its end, a temperature sensor arranged in the temperature measuring unit of the probe, a contact sensor arranged in a position shifter from the temperature measuring unit of the probe toward a thermometer body, a determining unit for determining whether a state of contact between the temperature measuring unit and a measurement target portion of a user is good or not, based on outputs of both the temperature sensor and the contact sensor, and a notifying unit for providing a notification according to a result of the determination by the determining unit. |
| US08400312B2 |
Operation assisting system
An operation assisting system. When an operator manipulates an operation instrument to perform an operation for a joint surgery including a hip replacement, the operation assisting system provides the operator with information on the orientation of a bone such as a pelvis and an appropriate direction of the operation instrument relative to the bone to assist the operator so as to complete the operation in an easy and accurate manner, which ensures a high degree of operation accuracy and reduces the cost of the system. |
| US08400311B2 |
Hospital bed having alert light
A bed includes a frame, a controller coupled to the frame, and a patient position detection system coupled to the frame and coupled to the controller. The patient position detection system has at least three modes of operation of varying sensitivities for determining whether a person supported on the frame has moved by a sufficient amount to activate an alarm. |
| US08400310B2 |
Automated hand cleaning reminder system for an entranceway
The present invention relates to an improved an automated hand cleaning reminder system having a disinfectant dispenser mounted proximate to an entranceway. When approaching the entranceway the visitor must first utilize a disinfectant dispenser to gain unalarmed entry or exit through the entranceway. When the disinfectant dispenser is utilized the disinfectant dispenser transmits a signal to a processor which then deactivates temporarily a motion/presence detector scanning an area immediately adjacent or close to the entranceway, and thus permits entry or exit for the visitor. At the same time, processor activates a light emitter to provide a visual indication to the visitor that passage is permitted, and, simultaneously also activates the access allowed audio tone to be played through a message conveying apparatus. If the dispenser has not been utilized, the proximity detector will remain armed and the processor then issues an access denied audio tone to be played through the message conveying apparatus, and, simultaneously also activates a flashing light emitter to provide a visual indication to the visitor that passage is not permitted. |
| US08400306B2 |
Laboratory device, laboratory rack assembly and method for coupling an RFID chip
Devices and methods for the identification of test tubes in a test tube rack having a RFID chip, and including an antenna structure elements for wireless coupling with the RFID chip, such that the location of the RFID chip determines the orientation of the test tube rack and the position of the test tube, and coupling of the RFID chips attached to the test tube racks is independent of the direction of insertion of the test tube rack. |
| US08400305B2 |
Method and apparatus for determining range information of a node in a wireless system
A method and apparatus for determining a range within a wireless communication system is provided herein. The range information can then be used to locate a node (e.g., an asset tag). During operation, the minimum transmission power of a source transceiver (e.g., an RFID reader) that enables a tag to be detected will be used to indicate distance. Changes in transmit power will be used to indicate relative changes in distance to a particular node. The reader will be configured to always operate at a transmission power that will result in a certain percentage (e.g., 50%) detection rate for a target transceiver (e.g., an RFID asset tag). As the reader moves closer to the tag, the minimum detection power will decrease; as it moves farther from the tag, the minimum detection power will increase. This information is displayed to give a general change in range information between the RFID reader and the asset tag (e.g., increasing range or decreasing range). An individual will be able to easily locate the asset tag by using the displayed information. |
| US08400303B2 |
Information processing system, information processing device, and information processing method
An information processing system includes an information processing device arranged in a vehicle, a portable device storing unique information, a specification information recording unit configured to record specification information having a predetermined relationship with the unique information, a first transmission unit configured to transmit a request signal requesting transmission of the unique information, a first reception unit configured to receive the unique information transmitted from the portable device, a position specifying unit configured to compare the received unique information with the specification information and specify whether or not the portable device is inside the vehicle, a detection unit configured to detect a human inside the vehicle, an alarm unit configured to set off an alarm, and an alarm control unit. |
| US08400302B2 |
Electric field sensing device
A sensing system is disclosed that uses at least one conductive plate and associated electronic circuitry to provide an output that is indicative of an object's position in relation to the at least one conductive plate. The sensing system is provided with a high impedance drive signal that varies as a result of the location of an object relative to the at least one conductive plate. The electronic circuitry receives a high impedance drive signal value as an input and a processor uses the value to calculate a digital output indicative of the object's position. The high impedance drive signal value is monitored over time enabling the objects position, displacement, pressure, movement, impact and energy to be determined. This data is output to a display and may also be transmitted to a person located remotely from the object being monitored. |
| US08400301B1 |
Window safety and security device
A window safety and security device detects unauthorized movement of a double-hung window, sliding window, or door upon which the safety and security device is installed and communicates an alarm in response to the detecting. The device includes a housing, a suction cup affixed to or integral with the housing configured to be removably attached to an inside glass pane of a first sash of a double-hung window, sliding window or door. An electrical switch is disposed in, on or affixed to the housing for contacting a portion of a second sash when the second sash is slid to a fixed position to actuate the switch. A light or a buzzer or both communicates a detected window or door movement sufficient to cause a change of state in the switch. |
| US08400296B2 |
Method and apparatus to automate data collection during a mandatory inspection
A system and method for verifying that an operator was sufficiently close to one or more items to be inspected during an inspection to actually inspect the components, and storing an indication to that effect in a memory accessible via a computer network. In addition to the indication, the memory can store other inspection related data, such as a starting time or ending time of the inspection, or maintenance information about the item that was input during the inspection. The system and method enable a third party application, such as an accounting program or a maintenance program, to access any of the inspection related data. |
| US08400294B2 |
Transit stop detection
Techniques are described that may be implemented in a portable electronic device to provide automatic detection of transit stops made by mass transit system vehicle in which a user of the device is a passenger. In an implementation, the portable electronic device includes an inertial sensor assembly to sense motion of the vehicle and generate a signal indicative of the vehicle motion. The inertial sensor assembly signal is used to detect the occurrence of a transit stop made by the vehicle. The portable electronic device can then display a prompt in response to detection of the transit stop. In embodiments, other measured data (e.g., elapsed time from a prior event, location information, direction, sound, and so on) may be used to verify the occurrence of the transit stop. |
| US08400291B2 |
Information display apparatus and computer readable medium having information display program
An information display apparatus includes a display unit including a non-volatile display medium. The information display apparatus further includes: a temperature detecting unit configured to detect a display unit temperature which is temperature of the display unit; a temperature determining unit configured to determine whether the display unit temperature is outside of a set temperature range which is predetermined based on characteristics of the display unit; and a display control unit configured to perform on the display unit a burn prevention display which is predetermined based on the characteristics, when the display unit temperature is outside of the set temperature range. |
| US08400289B2 |
Tire pressure monitoring system and method for the allocation of tire modules in a tire pressure monitoring system
Disclosed is a tire pressure monitoring system for motor vehicles, including a central unit (2, 7) with at least one trigger module (4), which is integrated into the central unit or connects through control lines (3) to the central unit, and with at least one tire module (6) arranged in a vehicle wheel (5), with the tire module being in communication with the central unit and the trigger module by means of wireless transmission technology, and with the tire pressure monitoring system including fewer trigger modules than tire modules. |
| US08400287B2 |
Method for assisting high-performance driving of a vehicle
An assistance method for performance driving of a vehicle; the assistance method includes the steps of: identifying a route used by the vehicle; on each section of the route, identifying the optimum point for the operation of an accelerator command, a brake command, a steering command and/or a gearbox command; identifying the current position of the vehicle along the route; identifying the next optimum point for the operation of a command; identifying a warning advance in accordance with an estimate of the reaction time of the driver and in accordance with the current speed and acceleration of the vehicle; and signalling to the driver to operate the command using the previously identified warning advance so that the driver actually operates the command at the optimum point of operation. |
| US08400284B2 |
System and method for controlling headlights on a vehicle in response to wiper operation
A method for controlling headlights on a vehicle includes detecting for a wiper switch state for a wiper switch on a vehicle, detecting wiper operations, incrementing a counter value by x until the counter value reaches a headlight ON threshold, counting toward a time threshold, decrementing the counter value by x until the counter value reaches a headlight OFF threshold value, and changing a state of the headlights based on the counter value reaching one of the headlight ON threshold and the headlight OFF threshold. Incrementing the counter value by x can occur in response to each detected wiper operation. Counting toward the time threshold can occur in response to detecting a wiper switch OFF state. Decrementing the counter value by x can occur in response to each instance of the time threshold elapsing with no change from the wiper switch OFF state. A plurality of intermediate counter values can be found between the headlight ON threshold and the headlight OFF threshold. A control system is also disclosed. |
| US08400282B2 |
Multi-function vibration actuator
A magnetic circuit including a pole piece, a magnet, and a yoke is supported by using a suspension where outer and inner circumferential portions thereof are connected to each other with a supporting member, and the outer circumferential portion of the suspension is fixed to protrude from a housing or an inner wall of a cover provided with a stepped portion in a direction passing over the magnetic circuit toward an inner portion, so that it is possible to limit a movable range of the magnetic circuit by using the outer circumferential portion of the suspension and to prevent inner components of a main body of the multi-function vibration actuator from being destructed at the time of being impacted due to falling. |
| US08400281B2 |
Wireless identification system using a directed-energy device as a tag reader
A wireless identification system can include a directed-energy device configured as a reader. The reader can include a charged particle generator configured to generate energized particles and a charge transformer configured to receive the energized particles that include charged particles from the charged particle generator and to output a wavefront including energized particles that include particles having substantially zero charge. The system can also include an identification tag configured to be activated when impinged by the wavefront from the reader so as to transmit a signal configured to be used by the reader. A method of using a directed-energy device as a tag reader in a wireless identification system can include generating a wavefront that includes particles at substantially zero charge, impinging an identification tag with the wavefront so as to activate the identification tag so as to send a signal and detecting a signal transmitted by the identification tag. |
| US08400275B2 |
Method and system of utilizing RFID tags for jointly processing task
A method of utilizing RFID tags for jointly processing a task and an associated system are provided. The method includes causing a plurality of RFID tags to enter a ready state, causing the RFID tags to enter an accessible state in turn, transmitting the task to the RFID tags, utilizing the RFID tags to jointly process the task, and reading a result from the RFID tags having processed the task. |
| US08400274B2 |
Accurate persistent nodes
A timing circuit that can function as an accurate persistent node in an RFID tag includes a power capture circuit for capturing power from a power source, and a counter circuit that provides a count representing a progression of time. The count can then be compared to a reference value representing a time constant of the circuit. |
| US08400272B2 |
Method and device for improving the signal to noise ratio (SNR) of a backscatter signal received from a radio frequency identification (RFID) tag
A method and device enables improving a signal to noise ratio (SNR) of a backscatter signal received from a radio frequency identification (RFID) tag. The method includes generating a continuous wave (CW) carrier signal at the reader device (step 505). An amplitude modulation (AM) noise component of the CW carrier signal is then detected (step 510). The AM noise component is inverted to an inverted noise signal (step 515), and the inverted noise signal is summed with the CW carrier signal to provide an AM noise cancelled carrier signal (step 520). The AM noise cancelled carrier signal is then transmitted from an antenna of the reader device (step 525), and the backscatter signal is received at the reader device in response to transmission of the AM noise cancelled carrier signal (step 530). |
| US08400270B2 |
Systems and methods for determining an operating state using RFID
Systems and methods for determining a binary status of a device are provided. A method for detecting an operating status of a device using a radio frequency identification (RFID) tag is provided. The method includes coupling a first portion of the RFID tag to a first portion of the device and coupling a second portion of the RFID tag to a second portion of the device, wherein the first portion of the device is moveable with respect to the second portion of the device, changing a position of the first portion of the device with respect to a position of the second portion of the device, detecting the change in position of the first device portion based on the movement of the first RFID tag portion, wherein the movement causes a change in a status of an RFID signal emitted by the RFID tag, and determining the status of the device based on the change in the RFID signal status. |
| US08400269B2 |
Methods and systems using polarization modulated electromagnetic waves
Methods and systems using polarization modulated electromagnetic waves. At least some of the illustrative embodiments are systems comprising a radio frequency identification (RFID) reader, and a RFID tag (the RFID tag communicatively coupled to the RFID reader),. The RFID tag is configured to transmit data to the RFID reader with data encoded in polarization of electromagnetic waves transmitted from the RFID tag. |
| US08400264B2 |
System and methods for automatically moving access barriers initiated by mobile transmitter devices
An operator system and related methods for automatically controlling access barriers which includes a base controller associated with at least one access barrier and at least one base receiver associated with the base controller. The system also includes at least one mobile transmitter that automatically and periodically generates at least one mobile signal detectable by the base receiver. The base controller selectively generates barrier movement commands upon receipt of the at least one mobile signal. Timers may be used to block receipt of any mobile signals for a period of time to prevent any further door movement. Such a system allows for hands-free operation of the access barrier. A discrete processing system may also be used to retrofit existing barrier operator systems for use in hands-free operation. |
| US08400262B2 |
Keyless entry device of vehicle
A keyless entry device of a vehicle includes: a transmission unit installed in the vehicle that transmits a search signal to a search range including an area inside the vehicle and a vicinity area outside the vehicle; a reply unit installed in a portable device carried by a user that transmits a reply signal when receiving the search signal at several locations within the search range; a determination unit that individually determines whether the portable device is present in the area inside the vehicle and the vicinity area outside the vehicle within the search range on the basis of the reply signal transmitted from the portable device; and a control unit that controls locking or unlocking of a door of the vehicle on the basis of the determination result of the determination unit. |
| US08400258B2 |
Method of remotely configuring a controller responsive to wireless signals
A method of remotely configuring a controller responsive to wireless signals includes entering a controller programming mode from a regular mode in response to at least one wireless signal corresponding to a first click pattern from a switch. The controller provides a first notification to indicate a first selected configurable feature of the controller. Each of a plurality of configurable features of the controller has a different assigned notification. The controller provides a second notification to indicate a second selected configurable feature in response to at least one wireless signal corresponding to a second click pattern from the switch. The method also includes exiting the programming mode. The notification may be a flashing of lights, a dimming of lights, an audible sound, an adjustment of a damper position, or a combination of these things. |
| US08400255B2 |
Oxygen-barrier packaged surface mount device
A method for producing a surface mount device includes providing a plurality of layers including a B-staged top layer and bottom layer, and a C-staged middle layer with an opening. A core device is inserted into the openings, and then the top and bottom layers are placed over and under, respectively, the middle layer. The layers are cured until the layers become C-staged. The core device is substantially surrounded by an oxygen-barrier material with an oxygen permeability of less than approximately 0.4 cm3·mm/m2·atm·day. |
| US08400251B2 |
Electronic component and method for manufacturing the same
An electronic component includes a multilayer composite including first insulating layers, second insulating layers, and a helical coil. The helical coil is disposed within the multilayer composite and includes a plurality of coil conductors connected to each other with a plurality of via hole conductors. The coil is located corresponding to the region defined by the second insulating layers when viewed in a stacking direction of the first and second insulating layers. The second insulating layers are located in the region coinciding with the locus of the coil without covering the via hole conductors when viewed in the stacking direction. |
| US08400250B2 |
Composite transformer
A composite (combined type of) transformer includes: a transformer core including a plurality of transformer magnetic leg portions, a transformer magnetic leg portion, and a pair of transformer bases; a plurality of inductor cores each including an inductor magnetic leg portions, inductor outer magnetic leg portions, and a pair of inductor bases; and a plurality of windings wound around the transformer magnetic leg portion and the inductor magnetic leg portions. The windings are wound to generate magnetic fluxes in such directions as to be cancelled out in a magnetic closed circuit in the transformer core. |
| US08400242B2 |
Park lock solenoid
A solenoid for a park lock mechanism wherein an annular frame has a reduced diameter at one end and receives a bobbin with a coil wound thereon with the bobbin projecting outward of the coil at one end and defining an integral bearing positioned in the one end of the annular frame. A magnetic permeable sintered metal bushing is interposed between the integrated bearing of the bobbin and the one end of the annular frame. A plunger is received in the bobbin for sliding movement relative thereto. The plunger has a first reduced section at one end that includes an element for connecting to a shifter and a second reduce section at its other end that projects out of said bobbin. The solenoid has two operating conditions, a first condition in which no magnetic force is applied to the plunger and a connected shifter is locked, and a second condition in which magnetic force is applied to the plunger and a connected shifter is unlocked for shifting. A manual release is provided for coacting with the plunger for putting the solenoid into the second condition in the absence of power. |
| US08400237B2 |
Circuit device including a nano-composite dielectric film
A circuit device includes a substrate 11, and a transmission line 10. The transmission line 10 includes a dielectric film 13 formed on the substrate 11, and a signal line formed on the dielectric film 13. The dielectric film 13 includes a nano-composite film in which particles of a first material are dispersed in a second material. |
| US08400236B2 |
Electronic component
An electronic component includes a laminated body including an insulating material layer made of a first dielectric material and a second insulating material layer made of a second dielectric material having a relative dielectric constant greater than that of the first dielectric material that are laminated to one another. An LC filter is defined by a coil included in the laminated body and a capacitor. The coil includes a coil conductor layer provided on the insulating material layer. The coil conductor layer is provided within a region including the insulating material layer. |
| US08400235B2 |
Active hybrids for antenna systems
In an exemplary embodiment, a fully monolithic active hybrid architecture can be configured to replace a ring hybrid, magic tee, branchline coupler, or 180° hybrid by providing similar functionality in an integrated monolithic solution. Exemplary embodiments of the active hybrids combine active implementations of power splitters, power combiners, and phase shifting elements in a novel fashion allowing for ultra-compact size and broadband performance. In an exemplary embodiment, the active hybrid replaces the typical hybrid couplers with active splitters and active combiners. Similarly, the delay lines and amplitude adjustment elements are replaced by active vector generators. Vector generators are magnitude and phase control circuits. The active hybrid results in certain advantages including being size independent of the operating frequency, wide frequency range of operation, and RF signals undergo a neutral or slight positive power gain, rather than power losses that occur in the passive prior art systems. |
| US08400234B2 |
Apparatus for removing leakage signal
An apparatus for removing a leakage signal includes a coupler including a transmission port through which a transmission signal is input, an antenna port through which the transmission signal is output to an antenna and a receiving signal is input from the antenna, and a receiving port through which the receiving signal is output; and a removing unit which outputs, to the receiving port, a leakage removing signal having a same magnitude as one of or a sum of a magnitude of a first leakage signal of the transmission signal, which is generated at the transmission port and input to the receiving port, and a magnitude of a second leakage signal of the transmission signal which is input to the receiving port through the antenna port, the leakage removing signal having an opposite phase to one of the phases or an aggregate phase of the first and second leakage signals. |
| US08400228B2 |
Redundancy system for a telecommunication system and related methods
A redundancy system for a co-channel telecommunication system and related methods. Implementations of the redundancy system may include at least a first modulator and a second modulator having a symbol mapper coupled to a parallel bit signal. The symbol mapper may be configured to route each of a plurality of parallel bits received through the parallel bit signal to a plurality of significant bit signals. In a first implementation, a plurality of significant bit signal multiplexers may be used to switch the plurality of parallel bit signals to allow the first and second modulators to operate in either a redundant or operating mode. In a second implementation, a premapped symbol (PMSI) encoder and a PMSI decoder may be used to transmit the plurality of significant bit signals across an interface bus as a real dual-data rate (DDR) signal and an imaginary DDR signal. |
| US08400227B2 |
Clock generator
A clock generator is provided, capable of automatically adjusting an output clock when process, voltage, or temperature variation occurs. The clock generator includes a current generator, for generating a first current and a second current according to a bias signal, an oscillator, coupled to the current generator, for generating a clock signal according to the first current, a frequency detector, coupled to the oscillator, for generating a control signal according to the clock signal and a reference signal, and a bias voltage adjuster, coupled to the current generator and the frequency detector, for adjusting the bias signal according to the control signal. When the signal frequency of the clock signal changes, the bias signal corresponds to the bias voltage adjuster, to adjust the first current and the second current. |
| US08400224B1 |
Programmable low noise amplifier and methods for use therewith
A low noise amplifier includes a programmable input stage, having a first gain that is programmable based on a first control signal. A programmable cascode stage, has a second gain that is programmable based on a second control signal. A programmable resistor stage controls the quality of a resonant tank circuit, based on a third control signal. |
| US08400221B2 |
Method and apparatus for biasing an amplifier
An apparatus and method for biasing each amplifier of an amplification stage provides that the voltage across each current sensing element of each amplifier of the amplification stage is measured. For each pair of voltage measurements taken, a sum and difference is calculated, where the sum is processed to determine minima peaks and the difference is averaged. A portion of the sum term and the average of the difference term are summed to yield the individual bias current conducted by a first amplifier of the amplification stage. The difference between a portion of the sum term and the average of the difference term is calculated to yield the individual bias current conducted by the second amplifier of the amplification stage. The bias current conducted by the first and second amplifiers may then be individually modified manually, or conversely, may be modified automatically based upon the bias current measurements taken. |
| US08400215B2 |
Power amplification device for satellite communication device
A power amplification device for a satellite communication device with a redundant configuration, in which a plurality of power amplifiers including a standby power amplifier are connected in a ring shape, and which easily switches connection to the standby power amplifier in a case of a failure in active power amplifiers without closing a detour route. The power amplification device for the satellite communication device includes a plurality of basic units each including: a plurality of power amplifiers including at least one standby power amplifier, which are arranged in parallel; a plurality of switches provided to input ends and output ends of the plurality of power amplifiers for switching connection paths; and bypass connection lines for connecting the plurality of switches in a ring shape, and the plurality of basic units are connected in cascade. |
| US08400214B2 |
Class AB output stage
This disclosure describes at least one class AB amplifier output stage circuit arrangement that can operate at low supply voltages, with minimum current generated. Furthermore, at least one class AB amplifier stage circuit arrangement described herein reacts favorably to a supply voltage, that is, exhibits a good power supply rejection ratio. Moreover, this disclosure describes class AB amplifier output stage circuit arrangements that include a negative channel metal oxide semiconductor (NMOS) transistor current mirror arrangement and a positive channel metal oxide semiconductor (PMOS) transistor current mirror arrangement. In some implementations, a monitoring circuit may be coupled to a class AB amplifier output stage circuit arrangement to offset mismatch that may occur in the class AB amplifier output stage. |
| US08400213B2 |
Complementary band-gap voltage reference circuit
A complementary band-gap voltage reference circuit comprising first and second groups of transistors, each group containing a first transistor of npn type and a second transistor of pnp type and the transistors of different types in the same group having different emitter current conduction areas. The emitter-collector paths of the first transistors of each group are connected in parallel so as to present differential base-emitter voltages. The second transistors of each group are connected with their emitter-collector paths in parallel with a base-emitter junction of the first transistor of the same group so as to present differential base-emitter voltages of the second transistors across the first and second groups of transistors. The output regulated voltage is an additive function of the differential base-emitter voltages and of additive base-emitter voltages of transistors with smaller emitter current conduction area and different type. |
| US08400211B2 |
Integrated circuits with reduced voltage across gate dielectric and operating methods thereof
An integrated circuit includes a first pass gate and a first receiver electrically coupled with the first pass gate. The first receiver includes a first N-type transistor. A first gate of the first N-type transistor is electrically coupled with the first pass gate. A first P-type bulk of the first N-type transistor is surrounded by a first N-type doped region. The first N-type doped region is surrounded by a first N-type well. The first N-type doped region has a dopant concentration higher than that of the first N-type well. |
| US08400210B2 |
Semiconductor apparatus
A semiconductor apparatus includes an individual chip designating code setting block configured to generate a plurality of individual chip designating codes which have different code values or at least two of which have the same code value, in response to a plurality of chip fuse signals; and an individual chip activation block configured to compare the plurality of individual chip designating codes with chip selection address in response to the plurality of chip fuse signals, and enable one of a plurality of individual chip activation signals based on a result of the comparison. |
| US08400209B2 |
Proximity detection
For proximity detection, capacitance of a sensing element to ground is measured as one or more objects move into or out of proximity to the sensing element. |
| US08400203B1 |
Integrated circuit with delay circuitry
The delay circuit, such as a clock circuit, of an integrated circuit operates with tolerance of variation in temperature. For example, the delay circuit has a temperature dependent current generator that has an adjustable temperature coefficient, such that a range of temperature coefficients is selectable at a particular current output. Also, the clock circuit of an integrated circuit operates with multiple versions of a current that controls a discharging rate and/or a charging rate between reference signals of timing circuitry. |
| US08400201B2 |
Delay signal generator
A delay clock generator includes a plurality of delay element arrays arranged in parallel; a feed side transfer line and a return side transfer line provided in each of the delay elements which make up the delay element arrays, and that transfer a clock signal in a feed direction and a return direction; a selector selecting a first transfer route that couples the feed side transfer lines to each other along the preceding and succeeding delay elements and a third transfer route that couples the return side transfer lines to each other along the preceding and succeeding delay elements, and a second transfer route that couples the feed side transfer lines and the return side transfer lines of each of the delay elements; and a decoder causing the selector to select the second transfer route for one of the delay elements in the delay element array. |
| US08400194B2 |
Interface system for a cog application
A current driving type transmitter using independent current signals, which can independently generate and transmit differential current indicating a logic state of data to be transmitted, using a difference between positive data current and negative data current without using external current, so that magnitudes of current applied to a pair of transmission lines can be kept constant without being influenced by the design of current sources and processing factors, a current driving type receiver using independent current signals, which can simultaneously convert a difference in levels of current, received through the transmission lines, into a voltage level by a single I-V converter, so that errors of a true line and a bar line can be lessened, and an interface system for COG application, which adopts the transmitter and receiver, so that distortion of transmitted signals can be reduced. |
| US08400190B2 |
Apparatus and method to tolerate floating input pin for input buffer
An integrated circuit device includes a pad adapted to receive a signal from an internal or external driver, and an input buffer circuit including an input terminal coupled to the pad. The input buffer circuit includes a pass transistor having a control terminal, a first conduction terminal connected to the pad, and a second conduction terminal connected to a first voltage. The input buffer circuit also includes a latch having a terminal electrically coupled to the control terminal of the pass transistor. The input buffer circuit further includes circuitry coupled to the latch, the circuitry including a feedback transistor having a control terminal electrically coupled to the pad, a first conduction terminal electrically coupled to a second voltage, and a second conduction terminal coupled to the latch. |
| US08400188B2 |
Methods, systems and arrangements for edge detection
A variety of edge-detection related devices, methods and systems are implemented in various fashions. One implementation is directed to an edge detector circuit for detecting an edge of an input signal and producing an output level-sensitive signal that is synchronous to a clock signal having an active edge corresponding to a transition from a first-signal level to a second-signal level. A first flip-flop has the input signal as a clock input and produces an internal level-sensitive signal and is reset by the output level-sensitive signal. Logic passes the level-sensitive signal when the clock signal is at the second-signal level and blocks the internal level-sensitive signal when the clock signal is at the first-signal level. A second flip-flop is set by the passed internal level-sensitive signal to produce the output level-sensitive signal. The second flip-flop is cleared in response to the output level-sensitive signal, a reset input and the clock signal. |
| US08400185B2 |
Driving circuit with zero current shutdown and a driving method thereof
Methods and circuits related to a driving circuit with zero current shutdown are disclosed. In one embodiment, a driving circuit with zero current shutdown can include: a linear regulating circuit that receives an input voltage source, and outputs an output voltage; a start-up circuit having a threshold voltage, the start-up circuit receiving an external enable signal; a first power switch receiving both the output voltage of the linear regulating circuit and the external enable signal, and that generates an internal enable signal, the internal enable signal being configured to drive a logic circuit; when the external enable signal is lower than a threshold voltage, the driving circuit is not effective; when the external enable signal is higher than the threshold voltage, the start-up circuit outputs a first current; and where the output voltage at the first output terminal is generated by the linear regulating circuit based on the first current. |
| US08400184B2 |
Semiconductor device and level shift circuit using the same
A level shift circuit includes: a pair of first and second P-channel transistors which are connected in a flip-flop manner and whose sources connected to a first power supply line; a pair of first and second N-channel transistors with the first N-channel transistor provided between the first P-channel transistor and a second power supply line and the second N-channel transistor provided between the second P-channel transistor and the second power supply line, in which input signals complementary to each other are inputted to their gates; and a current supply circuit provided between the first power supply line and a drain of the first N-channel transistor and between the first power supply line and a drain of the second N-channel transistor, respectively. The current supply circuit includes third and fourth N-channel transistors with their sources connected to drains of the first and second N-channel transistors and third and fourth P-channel transistors serving as current limiting elements with their one ends connected to the first power supply line and the other ends connected to drains of the third and fourth P-channel transistors. |
| US08400182B2 |
Wafer inspection device and semiconductor wafer inspection method using the same
A wafer inspection device, which inspects the electrical properties of a semiconductor wafer on which a semiconductor integrated circuit is formed, and the wafer inspection device has: a holding mechanism for holding a probe card; a wafer stage that holds the semiconductor wafer on the upper surface and is movably provided; and a pressing mechanism that are held and press the wafer stage against the probe card. The wafer stage is provided on the outer periphery with a seal ring. The seal ring forms a sealed space in a state where the wafer and the probe card are brought close to each other by contacting the probe card and is provided in such a manner as to reduce the pressure of the sealed space. |
| US08400169B2 |
Active discharge of electrode
The disclosure is directed to a capacitive sensor for measuring a small biomedical electrical charge originating from an object under test comprising input circuit elements having an electrode for sensing the charge to provide an output signal that is a function of the charge being measured, wherein the electrode has no electrical contact with the object; amplification circuit elements (A) connected to the input circuit elements; processing circuit elements configured for receiving and processing the amplified output signal and to provide the measurement; and conditioning and monitoring circuit elements coupled to at least the input circuit elements comprising monitoring circuit elements and conditioning circuit elements; (R1) wherein the monitoring circuit elements are configured for monitoring the amplified output signal to detect an error in a measurement that is greater than a preset value caused by charge buildup on the electrode; and wherein the conditioning circuit elements are configured to be activated for. discharging the electrode when the error in the measurement is detected by the monitoring circuit elements and the conditioning circuit elements are configured to be deactivated, when the error in the measurement is no longer detected. |
| US08400168B2 |
Pavement material microwave density measurement methods and apparatuses
A method of obtaining a material property of a pavement material from a microwave field generally includes generating a microwave frequency electromagnetic field of a first mode about the pavement material. The frequency response of the pavement material in the electromagnetic field can be measured, such as by a network analyzer. The measurement of the frequency response permits correlating the frequency response to a material property of the pavement material sample, such as the density. A method of correcting for the roughness of a pavement material divides the pavement into a shallow layer and a deep layer. Two planar microwave circuits measure the permittivity of the shallow and deep layer. The permittivities are correlated to correct for roughness. An apparatus for obtaining the density of a pavement sample includes a microwave circuit and a network analyzer. The network analyzer measures the frequency response to determine the density of the pavement material. |
| US08400164B2 |
Calibration and compensation for errors in position measurement
Methods and systems method for sensing a position of an object in a body include positioning a probe in the body, making measurements of mapping electrical currents passing between at least a first electrode on the probe and a plurality of second electrodes on a surface of the body, calibrating the measurements so as to compensate for one or more non-ideal features of the measurements including effects of system-dependent electrical coupling to one or more devices other than the first electrode and the second electrodes, and computing the position of the probe in the body using the calibrated measurements. |
| US08400163B2 |
Voltage detecting circuit
A voltage detecting circuit includes a switch group that selects any one of a plurality of battery cells connected in series, a sampling capacitor that maintains a potential difference between a positive electrode terminal and a negative electrode terminal of a battery cell selected by the switch group, a measuring part that outputs a detected voltage value signal corresponding to the potential difference between ends of the sampling capacitor, a transfer switch that transfers, to the measuring part, the potential difference caused between the ends of the sampling capacitor, a correction capacitor provided in parallel to input terminals of the measuring part, and between the transfer switch and the measuring part, and a discharge switch provided in parallel to the correction capacitor, and controlled so that a switching condition of the discharge switch is mutually exclusive with that of the transfer switch. |
| US08400162B1 |
Power management system and method
A method of monitoring battery capacity comprises determining a starting capacity of a battery; determining an activity coefficient for a device connected to the battery; determining a voltage and current profile for the battery using the starting capacity; determining a voltage and current operating point for the device using the activity value for the device; and determining an updated capacity of the battery using the voltage and current profile for the battery and the voltage and current operating point for the device. |
| US08400160B2 |
Combined propagation and lateral resistivity downhole tool
A combined resistivity tool incorporating both induction/propagation antennas and lateral resistivity antennas disposed in recesses of downhole tubulars, in which a lateral resistivity antenna includes an insulating base layer disposed in the recess; a toroidal antenna disposed over the insulating base layer; and a shield disposed over the recess. |
| US08400159B2 |
Casing correction in non-magnetic casing by the measurement of the impedance of a transmitter or receiver
Methods and related systems are described for determining the casing attenuation factor for various frequencies from measurements of the impedance of the transmitting or receiving coil of wire of. The compensation is based on two relationships. The first relationship is between one or more measured impedance parameters and the product of casing conductivity, casing thickness and electromagnetic frequency. The second relationship is between the casing correction factor and the product of casing conductivity, casing thickness and electromagnetic frequency. |
| US08400152B2 |
Method for k-space reconstruction in magnetic resonance inverse imaging
A method for parallel magnetic resonance imaging (“pMRI”) that does not require the explicit estimation of a coil sensitivity map is provided. Individual coil images are reconstructed from undersampled scan data that is acquired with a radio frequency (RF) coil array having multiple coil channels. An inverse operator is formed from autocalibration scan (ACS) data, and is applied to the acquired scan data in order to produce reconstruction coefficients. Missing k-space lines in the undersampled scan data are synthesized by interpolating k-space lines in the acquired scan data using the reconstruction coefficients. From the acquired scan data and the synthesized missing k-space lines, individual coil images are reconstructed and combined to form an image of the subject. |
| US08400151B2 |
Calibration method
A method for calibration of a magnetic resonance imaging system having a bore, a body coil mounted in the bore, a patient mat, a number of local coils mounted in the patient mat, an upconversion stage having a number of upconverters, and a processing stage, includes the steps of generating a calibration signal in the body coil; receiving the calibration signal at the local coils, upconverting the signal from the local coils in the upconversion stage, transmitting the upconverted signal to the processing stage, synchronously downconverting the signal in the processing stage using the calibration signal generated in the body coil, and processing the downconverted signal to generate an overall path complex gain. |
| US08400150B2 |
Magnetic resonance system and method for control thereof
A method to control a magnetic resonance system includes at least one protocol step for measurement data acquisition with the magnetic resonance system, and at least one operator interaction step which allows an operator to enter information that affects at least one subsequent step in the control of the magnetic resonance system. |
| US08400148B2 |
Magnetic resonance imaging apparatus
Magnetic resonance imaging apparatus enabling highly precise spectrum measurement even when resonance frequency changes during MRS or MRSI measurement. When a pulse sequence for suppressing water signals, and an MRS or MRSI pulse sequence are sequentially executed to carry out measurement using repetitive measurement for signal integration or repetitive measurement for phase encoding, signal Sig0 from water is measured with the pulse sequence for suppressing water signals in every repetitive measurement. When the resonance frequency of water deviates from an excitation band region, nuclear magnetization included in water molecules is not excited, so that water signal strength deceases, and therefore change of static magnetic field intensity can be detected by monitoring change of signal Sig0.When water signal strength decreases below a predetermined value, it is determined that resonance frequency has shifted, preliminary measurement for detecting water resonance frequency is performed, and various frequencies are corrected during the repetitive measurement. |
| US08400146B2 |
Stray field collector pad, and bio-molecule sensing module or biochip using the same
Provided is a stray field collector (SFC) pad and a bio-molecule sensing module or a biochip using the same, and more particularly, a SFC pad, in which probe or detection molecules are attached to a plurality of magnetic labels (magnetic particles or beads) and they are bonded to complementary molecules to enhance a stray field sensor signal of the magnetic labels remaining in the vicinity of the sensor, and a bio-molecule sensing module and a biochip using the same.The provided is related to qualitative as well as quantitative detection of magnetic labels, and the SFC pad which can increase an effective surface area sensitive to the magnetic labels by probe-detection molecular bond in a magnetic biosensor and collect the resultant stray field can enhance sensitivity, accuracy and resolution of the magnetic biosensor. |
| US08400144B2 |
Rotational position sensor having axially central sensor unit
A rotational position sensor includes a rotating body rotatably supported around a predetermined axis line by a bearing portion of a housing and a sensor unit having a movable sensor element arranged at the rotating body to detect a rotational angle position of the rotating body and a fixed sensor element arranged at the housing. The rotating body includes a tapered annular contact face defining a part of a virtual cone face with a vertex on the axis line and the bearing portion includes a tapered annular bearing face rotatably supporting the annular contact face on the virtual cone face. Accordingly, the rotating body is consistently located on the axis line due to an automatic alignment effect. Therefore, the rotational angle position of the rotating body can be detected with high accuracy even with occurrence of aging variation such as wearing at a bearing area. |
| US08400143B2 |
Signal processing circuit of rotation detector and rotation angle detector
A signal processing circuit for a rotation detector includes a rotational direction determining portion, an effective edge determining portion, a normal-rotation pulse request holding portion, a reverse-rotation pulse request holding portion, an output request signal outputting portion, a pulse outputting portion, a first resetting portion, and a second resetting portion. When one of the holding portions holds an output request signal, the pulse outputting portion outputs a pulse based on the output request signal. When the other one of the holding portions holds an output request signal and then a condition for holding the output request signal that is already held by the one of the holding portions is satisfied in a state where the one of the holding portions holds the output request signal, the second resetting portion resets the output request signal held by the other one of the holding portion. |
| US08400142B2 |
Linear position sensor with anti-rotation device
An anti-rotation device or assembly for preventing the rotation of a magnet in a linear position sensor and eliminating the risk of undesired magnetic field measurements and incorrect sensor signal outputs. In one embodiment, the anti-rotation device is an anti-rotation plate which is fixed to the housing of the linear position sensor and a magnet carrier which includes at least one finger extending into a receptacle defined in either the edge or the body of the magnet carrier to prevent the magnet carrier from rotating relative to the plate. In another embodiment, the magnet carrier includes a key and the magnet includes a groove. The key extends into the groove for preventing the rotation of the magnet in the magnet carrier. |
| US08400141B2 |
Apparatus for determining and/or monitoring a process variable
An apparatus for determining and/or monitoring at least one process variable. The apparatus includes: at least one energy input, via which the apparatus receives energy for operation of the apparatus. The invention includes features that: at least one measuring unit is provided, which measures energy applied to the energy input; and at least one control unit is provided, which, based on comparison of the measured energy with a desired value of the energy requirement, controls at least one unit of the apparatus. |
| US08400137B2 |
Reference voltage generation circuit, drive circuit, light emitting diode head, and image forming apparatus
A reference voltage generation circuit includes a current-mirror circuit formed of a plurality of MOS (Metal Oxide Semiconductor) transistors each having a source terminal connected to a power source and a gate terminal connected to with each other; and a plurality of transistors each connected to a drain terminal of each of the MOS transistors of the current-mirror circuit for controlling the current-mirror circuit, so that an output current of the current-mirror circuit is converted to a voltage to be output as a reference voltage. Each of the MOS transistors of the current-mirror circuit has the drain terminal connected to a collector terminal of each of the transistors. Accordingly, when a voltage of the power source varies, it is possible to maintain a collector voltage of each of the transistors at a specific level and a collector current of each of the transistors constant. |
| US08400136B2 |
Current mirror semiconductor device and a layout method of the same
A semiconductor device and a layout method of the same reduce a mismatch in a semiconductor device. The semiconductor device includes a first transistor unit providing a first path of current and a second transistor unit designed in a mirror structure to the first transistor unit and providing a second path of current. The layout of the second transistor unit has a shape identical to the first transistor unit and shifted in a first direction. The layout of the semiconductor device reduces a mismatch of the transistors occurring when masks are combined, and thereby reduces their offset. |
| US08400134B2 |
Apparatus and methodology for maximum power point tracking for a solar panel
Circuitry and methodology for tracking the maximum power point (MPP) of a solar panel is disclosed. The voltage and current generated by the solar panel are monitored and used to generate a pulse signal for charging a capacitor. The changes in the voltage and current generated by the solar panel are also monitored, and that information is used to generate a pulse signal for discharging the capacitor. The charging and the discharging pulse signals are used to charge and discharge the capacitor. A reference signal indicative of the charge level of the capacitor is generated. As the current and voltage generated by the solar panel approach the maximum power point (MPP), the frequency of the discharging pulse signal becomes progressively higher, so that the capacitor charging occurs in progressively smaller increments. When the MPP is reached, the reference signal level becomes steady because the charge level of the capacitor becomes steady. |
| US08400133B2 |
Output current detection of a voltage regulator
For output current detection of a voltage regulator, a sensing circuit is coupled to a high-side element of the regulator and detects the current therein to generate a sensing current. A simulation circuit is coupled to the sensing circuit and generates a summed current by simulation with the sensing current. A setting resistor is coupled to the simulation circuit and receives the summed current to provide an output for feedback control of the voltage regulator. |
| US08400132B2 |
Method of switching a PWM multi-phase voltage converter
A circuit may generate a clock signal with a variable period given by a ratio between an initial switching period and a number of phase circuits through which a current of a multi-phase PWM voltage converter flows. The circuit may include an adjustable current generator driven by a signal representing the number of phase circuits through which the current flows and configured to generate a current proportional to the number of phase circuits through which the current flows, and a tank capacitor charged by the adjustable current generator. The circuit may include a comparator of a voltage on the tank capacitor with a threshold value configured to generate a pulse of the clock signal when the threshold value is attained, and a discharge path of the tank capacitor, the discharge path being enabled during the pulses of the clock signal. |
| US08400131B2 |
Voltage converter and LED driver circuits with progressive boost, skip, and linear mode operation
A voltage converter circuit can include a boost converter having a switching transistor and configured to receive an input voltage, produce an output voltage and selectively operate in one of a boost mode, a skip mode and a linear mode. In the boost and skip modes, the boost converter can switch on and off the switching transistor at a switching frequency to produce an output voltage at magnitudes greater than input voltage magnitudes. In the linear mode, the boost converter can turn off the switching transistor at all times to pass the input voltage unboosted to produce an output voltage at magnitudes less than input voltage magnitudes. The boost converter can be configured to operate in the boost mode for input voltage magnitudes less than a first predetermined input voltage magnitude, in the skip mode for input voltage magnitudes between the first predetermined magnitude and a second predetermined input voltage magnitude greater than the first predetermined input voltage magnitude, and in the linear mode for input voltage magnitudes greater than the second predetermined input voltage magnitude. |
| US08400123B2 |
Voltage converter and voltage conversion method
A voltage converter includes input terminals configured to receive an input voltage, and output terminals configured to provide an output voltage and an output current. At least one first converter stage is connected between the input terminals and the output terminals, having at least one unipolar transistor, and configured to provide a first output current. At least one second converter stage is connected between the input terminals and the output terminals, having at least one bipolar transistor, and configured to provide a second output current. A control circuit is configured to control the first output current and the second output current such that there is a first output current range in which the first output current is higher than the second output current. |
| US08400117B2 |
Method for controlling the progressive charge of a motor vehicle alternator
A method for controlling the progressive charge of a motor vehicle alternator. The alternator comprises a stator, a rotor which is provided with an excitation coil, a voltage regulator which acts on an excitation current which is supplied to the excitation coil in order to regulate an output voltage of the alternator, and a device for controlling the progressive charge which, by means of limitation of the excitation current to a maximum value, determines a maximum mechanical torque which the alternator can collect on a thermal engine of the vehicle. The maximum mechanical torque is determined according to a speed of rotation (NALT) of the alternator, and the progressive charge control device comprises a so-called progressive charge return (PCR) signal which indicates the maximum value which the excitation current (lexc) can assume. When the excitation current assumes a stabilized value (G), the progressive charge return (PCR) signal is updated (H) so as to indicate a maximum current value of the excitation current which is equal to the stabilized value. |
| US08400116B2 |
Method and apparatus for calculating power-off duration time and state of charging of battery
An apparatus for controlling a battery includes a capacitor for charging a voltage when the apparatus is on and discharging a voltage when the apparatus is off, a discharging circuit for discharging the voltage charged in the capacitor; a first switching unit for connecting or disconnecting the capacitor to/from a predetermined power source for the purpose of charging of the capacitor; a second switching unit for connecting or disconnecting the capacitor to/from the discharging unit; a voltage measuring unit for measuring a voltage charged in the capacitor; and a controller for calculating a power-off duration time according to the measured voltage. This apparatus may continuously calculate a power-off duration time of a battery pack. |
| US08400112B2 |
Method for managing power limits for a battery
A method for managing power limits for a battery includes the step of increasing a minimum operating state of charge after an initial power capability has decreased to the point where a predefined full discharge power is not available at an initial minimum operating state of charge. The increased minimum operating state of charge can be chosen such that the full discharge power is available. The increased minimum state of charge may not be chosen to provide the full discharge power if the increased minimum state of charge is greater than a maximum low limit state of charge. |
| US08400109B2 |
Flashlight charger
A flashlight charger includes a bottom plate provided with a pressing element and an electrically conducting part fixedly connected to a top plate that partially covers the pressing element and the electrically conducting part. A flashlight to be charged is aligned and connected with the flashlight charger and then pushed backward relative to the flashlight charger to allow the charging terminals at one end of the flashlight charger to make good electrical contact with the corresponding charging ends of the flashlight while the flashlight is securely fastened with the flashlight charger. When charging is completed, the flashlight can be removed from the flashlight charger rapidly and conveniently. The flashlight charger features good and stable electrical contact in use. |
| US08400108B2 |
Method of charging and using an aseptic battery assembly with a removable battery pack
A battery assembly with a housing that contains a removable battery pack. The housing, which is sterilzable, has a head designed to couple to a power consuming device. The battery pack, which is not sterlizable, contains at least one rechargeable cell. The battery pack has a head dimensioned to fit the same charger socket that can receive a sterlizable battery. The battery pack has contacts that abut charger contacts. The housing has internal contacts. Collectively, the housing and battery pack are shaped so that, when the battery pack seats in the housing, the battery pack contacts abut the housing internal contacts. The housing internal contacts are connected to the housing external contacts for supply power to the power consuming device. A cover selectively holds the battery pack in the housing chamber. |
| US08400107B2 |
Charge status display apparatus and electric power supply control apparatus
When a user performs a short-press manipulation to A button or B button, a vehicle ID associated with either A button or B button having received the short-press manipulation is specified based on a button-vehicle correspondence table. Charge status information of a battery of a vehicle corresponding to the above associated vehicle ID is acquired from the vehicle. Thereby, the display device displays the acquired charge status information or the electric power supply is started to the battery of the vehicle corresponding to the vehicle ID. |
| US08400106B2 |
Recharging station and related electric vehicle
The invention relates to a recharging station (10) for recharging an electric vehicle (50) powered by energy storage means (52), said vehicle (50) being designed to follow a route via a point at which the recharging station (10) is situated, said station (10) including recharging means (12) suitable for recharging the storage means (52) of the electric vehicle (50) while said vehicle is in the vicinity of the station. The invention is characterized in that the recharging means (12) comprise a storage device (14) suitable for storing electrical energy delivered by an electrical energy source (16), and connection means (18) for electrically connecting the storage device (14) of the station (10) to the storage means (52) of the vehicle (50), and for transferring the energy stored in the storage device (14) of the station (10) to the storage means (52) of the electric vehicle (50). |
| US08400104B2 |
Gangable inductive battery charger
Gangable inductive battery chargers with integrated inductive coils are provided. A gangable inductive battery charger has at least one power supply module and at least one inductive charging cup module. The power supply module and the inductive charging cup module are interlockingly connectable through rail and slot mechanical connectors and an electrical connector. The inductive charging cup module has one or more charging cups that are capable of receiving a battery. A primary inductive coil embedded in the inductive charging cup module transfers power from the power supply module to a battery received by one of the one or more charging cups. The battery contains a secondary inductive coil for receiving power from the embedded primary coil. Multiple power supply and inductive charging cup modules may be interlockingly connected as needed. |
| US08400102B2 |
Assembled battery unit and vehicle
According to one of the embodiment, an assembled battery has a plurality of cells electrically connected in series. A charge amount difference detection circuit detects charge amount difference of the cells. Wherein, while a charging or discharge current is being applied to the cells, the charge amount difference detection circuit detects charge amount differences greater than a charge amount of a reference cell having a minimum charge amount, the charge amount differences of the cells are determined by addition of the charging or discharge currents during a period corresponding to the time differences between the reference cell and the other cells reaching a predetermined specific voltage, discharge switches are controlled by a switch controller, based on the charging amount differences. |
| US08400092B2 |
Motor drive component verification system and method
A technique is provided for verifying the proper selection, installation, communication and operability of components in power electronic systems, such as motor drives. A processing circuit is coupled to multiple components or subsystems that identify themselves to the processing system. An identification code is stored that is compared to a similar code built based upon the information reported by the components at the time of commissioning, operation or servicing. If the comparison indicates that all components are properly installed, and communicating and operative, operation may continue. The technique may be applied in parallel motor drives at a power layer level to allow separate and parallel verification of component and component operation in the parallel drives. |
| US08400091B2 |
Voltage regulator and cooling control integrated circuit
According to an embodiment of the invention, an apparatus is provided which includes a microprocessor, and a built-in temperature sensor configured to measure a temperature of the microprocessor as a reference temperature. The apparatus further includes external temperature sensors, where at least one of the external temperature sensors is configured to measure the temperature of the microprocessor. The microprocessor is configured to make an external temperature calibration using the reference temperature measured by the built-in temperature monitor. Each of the external temperature sensors is configured to monitor temperature information of a component and provide the temperature information to the microprocessor. |
| US08400089B2 |
Control electronics for brushless motors
An electronic control circuit for a brushless motor has an input power circuit providing a DC voltage and a microcontroller integrated circuit receiving the DC voltage. The microcontroller integrated circuit provides three-phase control signals according to a space vector control method. A microprocessor connected to the microcontroller integrated circuit executes supervisory control over the electronic control circuit. An inverter circuit receives the three-phase control signals from the microcontroller integrated circuit and provides driving signals to the brushless motor based on the three-phase control signals received from the microcontroller integrated circuit. |
| US08400083B2 |
Current detecting device, air conditioning apparatus, correction constant calculating system and correction constant calculating method
A current detecting device includes a current leveling unit, a first wire and a current detecting unit. The current leveling unit is configured to level a drive current that is passed through a motor drive unit to drive a motor. The first wire is configured and arranged to carry flow of a motor current that has been passed through the motor and the drive current that has been leveled by the current leveling unit. The current detecting unit is configured to detect a sum of the motor current flowing on the first wire and the drive current that has been leveled flowing on the first wire. |
| US08400081B2 |
Light emitting diode replacement lamp
Thermal management and control techniques for light emitting diode and other incandescent replacement light technologies using a current controller are disclosed. |
| US08400079B2 |
LED drive circuit, dimming device, LED illumination fixture, LED illumination device, and LED illumination system
An LED drive circuit in which an alternating voltage from a phase control dimmer is input and an LED is driven. The LED drive circuit comprises a phase angle detector for detecting the phase angle at which a phase control element inside the phase control dimmer switches from off to on; a switching power supply for feeding a current to the LED; a switching element connected in series to the LED; and a controller for controlling the switching power supply and the switching element in accordance with the output of the phase angle detector; wherein the controller places the switching element in an always-on state in a case in which the phase angle detected by the phase angle detector is equal to or less than a predetermined value, and the controller pulse-drives the switching element in a case in which the phase angle detected by the phase angle detector is greater than the predetermined value. |
| US08400075B2 |
Illumination circuit having bypass circuit controllable according to voltage change of series circuit thereof
An illumination circuit includes a series circuit including light sources connected in series between a high voltage node and a low voltage node, and break-protecting circuits. Each break-protecting circuit includes a control circuit and a bypass circuit. The bypass circuit is connected in parallel to at least one corresponding light source of the light sources. The control circuit is connected to the series circuit and the bypass circuit to detect a voltage change of the series circuit and control the bypass circuit to be in a conduct state or a blocked state according to the voltage change |
| US08400073B2 |
Backlight unit with controlled power consumption and display apparatus having the same
In a display apparatus having a backlight unit, a light unit includes plural light source strings commonly connected to an output terminal of a boosting circuit to generate light in response to a light source driving voltage. The light source strings are grouped into plural light generating groups. Plural driving circuits are respectively connected to the light generating groups, and each driving circuit sequentially outputs feedback voltages from the light source strings of a corresponding light generating group. A minimum voltage detecting circuit compares the feedback voltages with each other from the driving circuits to detect a minimum voltage and outputs a control signal according to the detected minimum voltage. A voltage control circuit controls a voltage level of the light source driving voltage in response to the control signal. Accordingly, although the number of the driving circuits increases, power consumption used in each driving circuit may be reduced. |
| US08400072B2 |
Light emitting device driver circuit driving light emitting device by positive and negative voltages and method for driving light emitting device by positive and negative voltages
The present invention discloses a light emitting device driver circuit and a method for driving a light emitting device. In the present invention, the secondary windings of a transformer provide positive and negative secondary voltages, so as to generate positive and negative output voltages. A light emitting device circuit is coupled between the positive and negative output voltages. As such, the specification to withstand high voltage for a device in the circuit is reduced. |
| US08400071B2 |
LED lamp power management system and method
An LED lamp power management system and method including an LED lamp having an LED controller 58; a plurality of LED channels 60 operably connected to the LED controller 58, each of the plurality of LED channels 60 having a channel switch 62 in series with at least one shunted LED circuit 83, the shunted LED circuit 83 having a shunt switch 68 in parallel with an LED source 80. The LED controller 58 reduces power loss in one of the channel switch 62 and the shunt switch 68 when LED lamp electronics power loss (Ploss) exceeds an LED lamp electronics power loss limit (Plim); and each of the channel switches 62 receives a channel switch control signal 63 from the LED controller 58 and each of the shunt switches 68 receives a shunt switch control signal 69 from the LED controller 58. |
| US08400067B2 |
Element substrate and light emitting device
A light emitting device and an element substrate which are capable of suppressing variations in the luminance intensity of a light emitting element among pixels due to characteristic variations of a driving transistor without suppressing off-current of a switching transistor low and increasing storage capacity of a capacitor. According to the invention, a depletion mode transistor is used as a driving transistor. The gate of the driving transistor is fixed in its potential or connected to the source or drain thereof to operate in a saturation region with a constant current flow. A current controlling transistor which operates in a linear region is connected in series to the driving transistor, and a video signal for transmitting a light emission or non-emission of a pixel is inputted to the gate of the current controlling transistor through a switching transistor. |
| US08400066B1 |
Magnetic logic circuits and systems incorporating same
Logic circuits based, at least in part, on use of spin-torque transfer (STT) to switch the magnetization—and hence the logic state—of a magnetic material are disclosed. Aspects of the invention include novel STT-based switching devices, new configurations of known STT-based devices into useful logic circuits, common logic circuits and system building blocks based on these new devices and configurations, as well as methods for inexpensively mass-producing such devices and circuits. |
| US08400063B2 |
Plasma sources
This invention relates to a plasma source in the form of plasma generator (13) which utilizes an antenna (11) and an RF source (12). The generated plasma flows into a chamber (14) and ions are accelerated out of the chamber (14) by grid (15). A body 16 is located in the volume for creating local losses and thereby reducing local plasma density. |
| US08400054B2 |
Organic optoelectronic component
An organic optoelectronic component comprises a substrate (1) with a first electrode (2) on the substrate (1), at least one first organic layer sequence (31) on the first electrode (2) which is suitable for emitting electromagnetic radiation during operation, an electrically conductive inorganic protective layer (4) on the at least one organic layer sequence (31) and a second electrode (5) on the protective layer (4). At least one of the first and second electrodes (2, 5) has a layer sequence (21, 22, 23) comprising a layer (21) comprising a transparent oxide and a layer (22) comprising a transparent metal. |
| US08400053B2 |
Carbon nanotube films, layers, fabrics, ribbons, elements and articles
Carbon Nanotube Films, Layers, Fabrics, Ribbons, Elements and Articles are disclosed. To make various articles, certain embodiments provide a substrate. Preformed nanotubes are applied to a surface of the substrate to create a non-woven fabric of carbon nanotubes. Portions of the non-woven fabric are selectively removed according to a defined pattern to create the article. To make a nanofabric, a substrate is provided. Preformed nanotubes are applied to a surface of the substrate to create a non-woven fabric of carbon nanotubes wherein the non-woven fabric is substantially uniform density. The nanofabrics and articles have characteristics desirable for various electrical systems such as memory circuits and conductive traces and pads. |
| US08400050B2 |
Piezoelectric vibrator having a restriction portion for restricting scattering of a getter material, oscillator, electronic equipment and radio-controlled timepiece
A piezoelectric vibrator includes a base substrate and a lid substrate which are bonded to each other with a cavity formed therebetween; a piezoelectric vibrating reed which has a pair of vibration arm portions extending in parallel and is mounted on the base substrate within the cavity; and a getter material of a metallic film that is formed on the base substrate or the lid substrate so as to be arranged within the cavity and improve a degree of vacuum within the cavity by being heated. A restriction portion, which is arranged in the cavity and restricts a scattering direction of the getter material evaporated by the heating to suppress a scattering amount scattering toward the vibration arm portion, is formed in the base substrate or the lid substrate. |
| US08400039B2 |
Outer rotor motor and method of manufacturing the same
An outer rotor motor comprises a rotor rotating about an axis, and a fixed stator. Provided over the inner peripheral surface of a cylindrical part of a fan connecting resin member are a ring-shaped yoke, a ring-shaped rotor magnet fixed to a fixing slot defined in the radially inner surface of the yoke, and yokes fixed to fixing slots defined in a radially inner surface of the rotor magnet. The rotor magnet is so magnetized that magnetic poles alternately change in a circumferential direction. The yoke covers a radially outer surface of the rotor magnet, and parts on a radially outer side of an axially upper surface and an axially lower surface of the rotor magnet. |
| US08400033B2 |
Unlocking actuator
An unlocking actuator for automatic unlocking of vehicle seat and manual unlocking of vehicle seat. Rotary torque generated by an electric motor in order to unlock a vehicle seat is transmitted to a rotary gear which is thereby rotated. A substantially sectorial insertion hole is formed in a pulley along the rotational direction and an abutting surface is formed on one end side of the insertion hole. A first inner cable has one end fixed to a first groove for winding formed in the outer circumferential part of the pulley and wound in the first groove for winding, and the other end connected with an unlocking mechanism. A second inner cable has one end fitted idly in a second groove for winding formed in the outer circumferential part of the pulley and wound in the second groove for winding, and the other end connected with an unlocking operation rod. |
| US08400030B1 |
Hybrid electric transmission fluid
A dispersant additive composition, a lubricant composition containing the dispersant additive, a transmission containing the dispersant additive, and a method of providing a versatile lubricating fluid. The dispersant includes a reaction product of a hydrocarbyl substituted carboxylic acid or anhydride and an amine. The reaction product has a nitrogen content up to 10,000 ppm by weight, and a boron plus phosphorus to nitrogen ((B+P)/N) weight ratio of from 0:1 to about 0.8:1. The dispersant additive composition is effective to provide an electrical conductivity to a lubricant composition containing the dispersant additive composition and a metal detergent of less than about 1700 pS/m. |
| US08400029B2 |
Rotating electrical machine having a plurality of cooling medium paths
A rotating electrical machine includes: a stator that includes a cylindrical stator core and a stator winding wire wound around the stator core; and a rotor disposed facing the stator via a gap; wherein at least one cooling medium path extending in a direction of a central axis of the stator core is provided in the stator; and the cooling medium path is inclined relative to the central axis of the stator core. |
| US08400026B2 |
Circuits and methods for controlling supercapacitors and kits for providing the same
A circuit can include a supercapacitor switch including first and second terminals, that is configured to electrically couple the terminals to one another in a closed position and to electrically de-couple the terminals from one another in an open position responsive to a supercapacitor switch control signal. A first supercapacitor has a first terminal that is electrically coupled to the first terminal of the supercapacitor switch and has a second terminal that is electrically coupled to a reference voltage. A second supercapacitor has a first terminal that is electrically coupled to the second terminal of the supercapacitor switch and has a second terminal that is electrically coupled to the reference voltage. |
| US08400021B2 |
Wireless energy transfer with high-Q sub-wavelength resonators
Described herein are embodiments of transferring electromagnetic energy that includes a first electromagnetic resonator structure receiving energy from an external power supply, said first resonator structure may have a first mode with a resonant frequency ω1, an intrinsic loss rate Γ1, and a first Q-factor Q1=ω1L1/R1ohm+R1rad). A second electromagnetic resonator structure being positioned distal from said first resonator structure and not electrically wired to the first resonator structure, said second resonator structure having a second mode with a resonant frequency ω2, an intrinsic loss rate Γ2, and a second Q-factor Q2=ω2L2/(R2ohm+R2rad). The electromagnetic energy may be transferred from said first resonator structure to said second resonator structure over a distance D that is smaller than each of the resonant wavelengths λ1 and λ2 corresponding to the resonant frequencies ω1 and ω2, respectively, where the characteristic sizes of the resonator structures are less than the resonant wavelengths and where Q1>100, Q2>100, R1ohm>R1rad, and R2ohm>R2rad. |
| US08400018B2 |
Wireless energy transfer with high-Q at high efficiency
Described herein are embodiments of a source high-Q resonator optionally coupled to an energy source, and a second high-Q resonator, optionally coupled to an energy drain that may be located a distance from the source resonator. The source resonator and the second resonator may be coupled to provide κ/sqrt(Γ1Γ2)>0.2 via near-field wireless energy transfer among the source resonator and the second resonator. |
| US08400015B2 |
Highly available node redundancy power architecture
According to one embodiment, an apparatus for providing node redundant power to a system includes a plurality of devices, with each device including a power supply. Each power supply includes a first direct current (DC) input coupled to a first input of an OR logic gate, and a second DC input representing by an alternating current (AC) input. The second DC input is coupled to a second input of the OR logic gate, and at least one DC output is coupled to an output of the OR logic gate. Each power supply also includes a backup power supply for supplying a voltage coupled to a common node. The OR logic gate provides DC voltage to the DC output to power the system from the first DC input only when voltage from the AC input is not available. |
| US08400006B2 |
Hydrodynamic array
There are a large number of sites in the world's oceans and rivers that can provide a significant, viable, and cost effective source of renewable energy. Many are strategically located close to populated areas where these sites can be used to harness energy using ecologically benign hydrodynamic technology. A hydrodynamic array comprises multiple hydrodynamic elements for producing electricity by the motion of ocean tides or river currents and forces acting on the hydrodynamic array, which is immersed in ocean tides or river currents and which is in motion relative to the ocean tides or river currents. |
| US08400005B2 |
Generating energy from fluid expansion
A turbine wheel is rotatable in response to expansion of a working fluid flowing from near an inlet side towards an outlet side of the turbine wheel. The turbine wheel may receive the working fluid radially into the inlet side of the turbine wheel and output the working fluid axially from its outlet side. A generator has a stator and a rotor. The rotor may be coupled to the turbine wheel and may rotate at the same speed as the turbine wheel when the turbine wheel rotates. In certain instances, the generator is adjacent the inlet side of the turbine wheel. |
| US08399993B2 |
Embedded package and method for manufacturing the same
An embedded package includes a first semiconductor chip having a first conductive line which has a first sunken area, a second semiconductor chip having a second conductive line which has a second sunken area, wherein the first semiconductor chip and the second semiconductor chip are arranged facing each other, and wherein the first sunken area and the second sunken area are arranged facing each other, a core layer surrounding the first semiconductor chip and the second semiconductor chip, wherein the core layer has a first circuit pattern coupled to an external terminal; and a bump formed in the first and second sunken areas, wherein the bump is coupled to the first circuit pattern. |
| US08399989B2 |
Metal pad or metal bump over pad exposed by passivation layer
A circuitry component comprising a semiconductor substrate, a pad over said semiconductor substrate, a tantalum-containing layer on a side wall and a bottom surface of said pad, a passivation layer over said semiconductor substrate, an opening in said passivation layer exposing said pad, a titanium-containing layer over said pad exposed by said opening, and a gold layer over said titanium-containing layer. |
| US08399988B2 |
High performance sub-system design and assembly
A multiple integrated circuit chip structure provides interchip communication between integrated circuit chips of the structure with no ESD protection circuits and no input/output circuitry. The interchip communication is between internal circuits of the integrated circuit chips. The multiple integrated circuit chip structure has an interchip interface circuit to selectively connect internal circuits of the integrated circuits to test interface circuits having ESD protection circuits and input/output circuitry designed to communicate with external test systems during test and burn-in procedures. The multiple interconnected integrated circuit chip structure has a first integrated circuit chip mounted to one or more second integrated circuit chips to physically and electrically connect the integrated circuit chips to one another. The first integrated circuit chips have interchip interface circuits connected each other to selectively communicate between internal circuits of the each other integrated circuit chips or test interface circuits, connected to the internal circuits of each integrated circuit chip to provide stimulus and response to said internal circuits during testing procedures. A mode selector receives a signal external to the chip to determine whether the communication is to be with one of the other connected integrated circuit chips or in single chip mode, such as with the test interface circuits. ESD protection is added to the mode selector circuitry. |
| US08399987B2 |
Microelectronic devices including conductive vias, conductive caps and variable thickness insulating layers
Microelectronic devices include a conductive via that extends into a substrate face and that also protrudes beyond the substrate face to define a conductive via end surface and a conductive via sidewall that extends from the end surface towards the substrate face. A conductive cap is provided on the end surface, the conductive cap including a conductive cap body that extends across the end surface and a flange that extends from the conductive cap body along the conductive via sidewall towards the substrate face. Related fabrication methods are also described. |
| US08399984B2 |
Semiconductor package
A semiconductor package comprises a semiconductor chip, through electrodes and cooling parts. The semiconductor chip has bonding pads on an upper surface thereof. The through-electrodes are formed in the semiconductor chip. The cooling parts are formed in the semiconductor chip and on the upper surface of the semiconductor chip in order to dissipate heat. |
| US08399983B1 |
Semiconductor assembly with integrated circuit and companion device
A semiconductor assembly with an integrated circuit (IC) and a companion device. An exemplary semiconductor assembly includes a printed circuit board (PCB) and first and second ICs. The PCB has first contacts on a top surface and second contacts on a bottom surface. The first contacts are vertically aligned with the second contacts and are electrically coupled by vias in the PCB. The first IC has first terminals respectively coupled to the first contacts of the PCB, the first terminals including first input/output (IO) terminals. The second IC includes at least one die, and second terminals coupled to at least a portion of the second contacts of the PCB. The second terminals include second IO terminals of the companion die, and are respectively coupled to those of the second contacts that are vertically aligned with those of the first contacts respectively coupled to the first IO terminals. |
| US08399982B2 |
Nanotube-based directionally-conductive adhesive
A tape adhesive type material is directionally conductive. According to an example embodiment of the present invention, carbon nanotubes (212, 214, 216, 218) are configured in a generally parallel arrangement in a tape base type material (210). The carbon nanotubes conduct (e.g., electrically and/or thermally) in their generally parallel direction and the tape base type material inhibits conduction in a generally lateral direction. In some implementations, the tape base material is arranged between integrated circuit components (220, 230), with the carbon nanotubes making a conductive connection there between. This approach is applicable to coupling a variety of components together, such as integrated circuit dies (flip chip and conventional dies) to package substrates, to each other and/or to leadframes. |
| US08399981B2 |
Ball grid array with improved single-ended and differential signal performance
An improved system and method for assigning power and ground pins and single ended or differential signal pairs for a ball grid array semiconductor package. In certain embodiments, the system uses a hexagonal pattern where the grid may be represented by a multiplicity of nested hexagonal patterns. |
| US08399980B2 |
Electronic component used for wiring and method for manufacturing the same
A wiring electronic component of the present invention is incorporated into an electronic device package in which a circuit element including a semiconductor chip is disposed and in which the circuit element is connected to a wiring pattern on the back face and also connected, via vertical wiring, to external electrodes located on the front face opposite the wiring pattern. The wiring electronic component is composed of an electrically conductive support portion, which serves as an electroforming mother die, and a plurality of vertical wiring portions formed through electroforming such that they are integrally connected to the support portion. |
| US08399978B2 |
Power semiconductor chip package
A device includes a vertical power semiconductor chip having an epitaxial layer and a bulk semiconductor layer. A first contact pad is arranged on a first main face of the power semiconductor chip and a second contact pad is arranged on a second main face of the power semiconductor chip opposite to the first main face. The device further comprises an electrically conducting carrier attached to the second contact pad. |
| US08399977B2 |
Resin-sealed package and method of producing the same
A method of producing a resin-sealed package is provided with: providing an electronic component which has a plurality of terminals on one face, a first support member and a second support member; temporarily fixing said electronic component to a surface of said first support member by a first adhesive agent layer, to face said terminals with said first support member; fixing said second support member having a second adhesive agent layer to said electronic component while interposing said electronic component between said first support member and said second support member to face said second adhesive agent layer with a back face side of said electronic component; resin sealing said electronic component between said first support member and said second support member; peeling said first support member and said first adhesive agent layer from said electronic component and a sealing resin; and stacking an insulating resin layer and a wiring layer which is electrically connected to said terminals of said electronic component, on said electronic component and said sealing resin. |
| US08399975B2 |
Stacked semiconductor package
A stacked semiconductor package includes a substrate having an upper surface and a lower surface, and divided into a first region and a second region that adjoins the first region; a support member formed in the second region on the upper surface of the substrate; and a semiconductor chip module including a plurality of semiconductor chips each of which is bent and has bonding pads near one lower edge of a declining slope of a first surface thereof and which are stacked on the support member in a step-like shape such that their bonding pads face the first region and are electrically connected with the substrate. |
| US08399972B2 |
Overmolded semiconductor package with a wirebond cage for EMI shielding
According to one exemplary embodiment, an overmolded package includes a component situated on a substrate. The overmolded package further includes an overmold situated over the component and the substrate. The overmolded package further includes a wirebond cage situated over the substrate and in the overmold, where the wirebond cage surrounds the component, and where the wirebond cage includes a number of wirebonds. The wirebond cage forms an EMI shield around the component. According to this exemplary embodiment, the overmolded package further includes a conductive layer situated on a top surface of the overmold and connected to the wirebond cage, where the conductive layer forms an EMI shield over the component. |
| US08399971B2 |
Packaged microelectronic devices and methods for manufacturing packaged microelectronic devices
Packaged microelectronic devices and methods of manufacturing packaged microelectronic devices are disclosed herein. In one embodiment, a method of manufacturing a microelectronic device includes forming a stand-off layer over a plurality of microelectronic dies on a semiconductor workpiece, and removing selected portions of the stand-off layer to form a plurality of stand-offs with the individual stand-offs positioned on a backside of a corresponding die. The method further includes cutting the semiconductor workpiece to singulate the dies, and attaching the stand-off on a first singulated die to a second die. |
| US08399968B2 |
Non-leaded integrated circuit package system
A non-leaded integrated circuit package system is provided providing a die paddle of a lead frame, forming a dual row of terminals including outer terminal pads and inner terminal pads, and selectively fusing an extension between the die paddle and instances of the inner terminal pads. |
| US08399966B2 |
Inserts for directing molding compound flow and semiconductor die assemblies
Flow diverting structures for preferentially impeding, redirecting or both impeding and redirecting the flow of flowable encapsulant material, such as molding compound, proximate a selected surface or surfaces of a semiconductor die or dice during encapsulation are disclosed. Flow diverting structures may be included in or associated with one or more portions of a lead frame, such as a paddle, tie bars, or lead fingers. Flow diverting structures may also be inserted into a mold in association with semiconductor dice carried on non-lead frame substrates, such as interposers and circuit boards, to preferentially impede, redirect or both impede and redirect the flow of molding compound flowing between and over the semiconductor dice. |
| US08399965B2 |
Layer structure with EMI shielding effect
A layer structure with an electromagnetic interference (EMI) shielding effect is applicable for reducing an EMI effect caused by signal transmission between through silicon vias, so as to effectively provide the EMI shielding effect between electrical interconnections of a three-dimensional (3D) integrated circuit. By forming EMI-shielding through silicon vias at predetermined positions between the through silicon vias used for signal transmission, a good EMI shielding effect can be attended, and signal distortion possibly caused by the EMI effect can be reduced between different chips or substrates. |
| US08399964B2 |
Multilayer structures for magnetic shielding
A magnetic shield is presented. The shield may be used to protect a microelectronic device from stray magnetic fields. The shield includes at least two layers. A first layer includes a magnetic material that may be used to block DC magnetic fields. A second layer includes a conductive material that may be used to block AC magnetic fields. Depending on the type of material that the first and second layers include, a third layer may be inserted in between the first and second layers. The third layer may include a non-conductive material that may be used to ensure that separate eddy current regions form in the first and second layers. |
| US08399963B2 |
Chip package and fabrication method thereof
A chip package includes a substrate having a pad region, a device region, and a remained scribe region located at a periphery of the substrate; a signal and an EMI ground pads disposed on the pad region; a first and a second openings penetrating into the substrate to expose the signal and the EMI ground pads, respectively; a first and a second conducting layers located in the first and the second openings and electrically connecting the signal and the EMI ground pads, respectively, wherein the first conducting layer and the signal pad are separated from a periphery of the remained scribe region, and wherein a portion of the second conducting layer and/or the EMI ground pad extend(s) to a periphery of the remained scribe region; and a third conducting layer surrounding the periphery of the remained scribe region to electrically connect the second conducting layer and/or the EMI ground pad. |
| US08399961B2 |
Tuning the efficiency in the transmission of radio-frequency signals using micro-bumps
A device includes a die including a main circuit and a first pad coupled to the main circuit. A work piece including a second pad is bonded to the die. A first plurality of micro-bumps is electrically coupled in series between the first and the second pads. Each of the plurality of micro-bumps includes a first end joining the die and a second end joining the work piece. A micro-bump is bonded to the die and the work piece. The second pad is electrically coupled to the micro-bump. |
| US08399959B2 |
Programmable poly fuse
According to one exemplary embodiment, a programmable poly fuse includes a P type resistive poly segment forming a P-N junction with an adjacent N type resistive poly segment. The programmable poly fuse further includes a P side silicided poly line contiguous with the P type resistive poly segment and coupled to a P side terminal of the poly fuse. The programmable poly fuse further includes an N side silicided poly line contiguous with the N type resistive poly segment and coupled to an N side terminal of the poly fuse. During a normal operating mode, a voltage less than or equal to approximately 2.5 volts is applied to the N side terminal of the programmable poly fuse. A voltage higher than approximately 3.5 volts is required at the N side terminal of the poly fuse to break down the P-N junction. |
| US08399949B2 |
Photonic systems and methods of forming photonic systems
Some embodiments include photonic systems. The systems may include a silicon-containing waveguide configured to direct light along a path, and a detector proximate the silicon-containing waveguide. The detector may comprise a detector material which has a lower region and an upper region, with the lower region having a higher concentration of defects than the upper region. The detector material may comprise germanium in some embodiments. Some embodiments include methods of forming photonic systems. |
| US08399945B2 |
Semiconductor light receiving element
A semiconductor light detecting element includes: a semiconductor substrate; and a distributed Bragg reflector layer of a first conductivity type, an optical absorption layer, and a semiconductor layer of a second conductivity type, sequentially laminated on the semiconductor substrate. The distributed Bragg reflector layer includes first and second alternately laminated semiconductor layers with different band-gap wavelengths, sandwiching the wavelength of detected incident light. The sum of thicknesses a first and a second semiconductor layer is approximately one-half the wavelength of the incident light detected. |
| US08399940B2 |
Package structure having MEMS elements and fabrication method thereof
A package structure having MEMS elements includes: a wafer having MEMS elements, electrical contacts and second alignment keys; a plate disposed over the MEMS elements and packaged airtight; transparent bodies disposed over the second alignment keys via an adhesive; an encapsulant disposed on the wafer to encapsulate the plate, the electrical contacts and the transparent bodies; bonding wires embedded in the encapsulant and each having one end connecting a corresponding one of the electrical contacts and the other end exposed from a top surface of the encapsulant; and metal traces disposed on the encapsulant and electrically connected to the electrical contacts via the bonding wires. The present invention eliminates the need to form through holes in a silicon substrate as in the prior art so as to reduce fabrication costs. Further, the present invention accomplishes wiring processes by using a common alignment device to thereby reduce equipment costs. |
| US08399939B2 |
Color selective photodetector and methods of making
A photoelectric device, such as a photodetector, can include a semiconductor nanowire electrostatically associated with a J-aggregate. The J-aggregate can facilitate absorption of a desired wavelength of light, and the semiconductor nanowire can facilitate charge transport. The color of light detected by the device can be chosen by selecting a J-aggregate with a corresponding peak absorption wavelength. |
| US08399936B2 |
Through substrate via semiconductor components
A structure and method of forming through substrate vias in forming semiconductor components are described. In one embodiment, the invention describes a method of forming a through substrate via by partially filling an opening with a fill material, and forming a first insulating layer over the first fill material thereby forming a gap over the opening. The method further includes forming a second insulating layer to close the gap thereby forming an enclosed cavity within the opening. |
| US08399930B2 |
Method of manufacturing a semiconductor device having a contact plug
There is provided a semiconductor device that includes: a transistor having a gate electrode, a source region, and a drain region; a first inter-layer insulation film covering the transistor; a first contact plug formed penetrating through the first inter-layer insulation film and connected to either the source region or the drain region; a second inter-layer insulation film covering the first contact plug; a groove extending in the second inter-layer insulation film in a same direction as an extending direction of the gate electrode and exposing a top surface of the first contact plug at a bottom thereof; a second contact plug connected to the first contact plug and formed in the groove; and a wiring pattern extending on the second inter-layer insulation film so as to traverse the groove and integrated with the second contact plug. |
| US08399925B2 |
Termination structure with multiple embedded potential spreading capacitive structures for trench MOSFET and method
A termination structure with multiple embedded potential spreading capacitive structures (TSMEC) and method are disclosed for terminating an adjacent trench MOSFET atop a bulk semiconductor layer (BSL) with bottom drain electrode. The BSL has a proximal bulk semiconductor wall (PBSW) supporting drain-source voltage (DSV) and separating TSMEC from trench MOSFET. The TSMEC has oxide-filled large deep trench (OFLDT) bounded by PBSW and a distal bulk semiconductor wall (DBSW). The OFLDT includes a large deep oxide trench into the BSL and embedded capacitive structures (EBCS) located inside the large deep oxide trench and between PBSW and DBSW for spatially spreading the DSV across them. In one embodiment, the EBCS contains interleaved conductive embedded polycrystalline semiconductor regions (EPSR) and oxide columns (OXC) of the OFLDT, a proximal EPSR next to PBSW is connected to an active upper source region and a distal EPSR next to DBSW is connected to the DBSW. |
| US08399919B2 |
Unit block circuit of semiconductor device
A unit block circuit of a semiconductor device includes a first well, a first pickup unit configured to form a closed loop over the first well, a first transistor including a first gate and a first active region, and formed within the first pickup unit, and a first reservoir capacitor formed in a spare within the first pickup unit and arranged in a major-axis direction of the first gate of the first transistor, wherein the first reservoir capacitor comprises a second active region and a second gate, the second gate being formed over the second active region. |
| US08399918B2 |
Electronic device including a tunnel structure
An electronic device can include a tunnel structure that includes a first electrode, a second electrode, and tunnel dielectric layer disposed between the electrodes. In a particular embodiment, the tunnel structure may or may not include an intermediate doped region that is at the primary surface, abuts a lightly doped region, and has a second conductivity type opposite from and a dopant concentration greater than the lightly doped region. In another embodiment, the electrodes have opposite conductivity types. In a further embodiment, an electrode can be formed from a portion of a substrate or well region, and the other electrode can be formed over such portion of the substrate or well region. |
| US08399915B2 |
Semiconductor device
Provided is a semiconductor device which can reduce on-resistance by improving hole mobility of a channel region. A trench gate type MOSFET (semiconductor device) is provided with a p+-type silicon substrate whose crystal plane of a main surface is a (110) plane; an epitaxial layer formed on the silicon substrate; a trench, which is formed on the epitaxial layer and includes a side wall parallel to the thickness direction (Z direction) of the silicon substrate; a gate electrode formed inside the trench through a gate dielectric film; an n-type channel region formed along the side wall of the trench; and a p+-type source region and a p−-type drain region which are formed to sandwich the channel region in the thickness direction (Z direction) of the silicon substrate. The trench is formed to have the crystal plane of the side wall as a (110) plane. |
| US08399913B2 |
Monolithic integrated circuit
A field-effect semiconductor device such as a HEMT or MESFET is monolithically integrated with a Schottky diode for feedback, regeneration, or protection purposes. The field-effect semiconductor device includes a main semiconductor region having formed thereon a source, a drain, and a gate between the source and the drain. Also formed on the main semiconductor region, preferably between gate and drain, is a Schottky electrode electrically coupled to the source. The Schottky electrode provides a Schottky diode in combination with the main semiconductor region. A current flow is assured from Schottky electrode to drain without interruption by a depletion region expanding from the gate. |
| US08399912B2 |
III-nitride power device with solderable front metal
Some exemplary embodiments of a III-nitride power device including a HEMT with multiple interconnect metal layers and a solderable front metal structure using solder bars for external circuit connections have been disclosed. The solderable front metal structure may comprise a tri-metal such as TiNiAg, and may be configured to expose source and drain contacts of the HEMT as alternating elongated digits or bars. Additionally, a single package may integrate multiple such HEMTs wherein the front metal structures expose alternating interdigitated source and drain contacts, which may be advantageous for DC-DC power conversion circuit designs using III-nitride devices. By using solder bars for external circuit connections, lateral conduction is enabled, thereby advantageously reducing device Rdson. |
| US08399909B2 |
Tetra-lateral position sensing detector
The present invention is directed to a position sensing detector made of a photodiode having a semi insulating substrate layer; a buffered layer that is formed directly atop the semi-insulating substrate layer, an absorption layer that is formed directly atop the buffered layer substrate layer, a cap layer that is formed directly atop the absorption layer, a plurality of cathode electrodes electrically coupled to the buffered layer or directly to the cap layer, and at least one anode electrode electrically coupled to a p-type region in the cap layer. The position sensing detector has a photo-response non-uniformity of less than 2% and a position detection error of less than 10 μm across the active area. |
| US08399908B2 |
Programmable metallization memory cells via selective channel forming
Methods for making a programmable metallization memory cell are disclosed. |
| US08399904B2 |
Light emitting device and lighting system having the same
Provided is a light emitting device. The light emitting device includes a plurality of metal layers including first and second metal layers spaced from each other, a first insulation film disposed on a top surface of the plurality of metal layers, the first insulation film having a width wider than an interval between the plurality of metal layers, a light emitting chip disposed on the first metal layer of the plurality of metal layers, and a resin layer disposed on the first metal layer, the first insulation film, and the light emitting chip. The first metal layer includes a first base part dispose on the light emitting chip and a first side part bent from the first base part on an outer portion of the first base part. |
| US08399903B2 |
LED lamps
A high power LED lamp has a GaN chip placed over an AlGaInP chip. A reflector is placed between the two chips. Each of the chips has trenches diverting light for output. The chip pair can be arranged to produce white light having a spectral distribution in the red to blue region that is close to that of daylight. Also, the chip pair can be used to provide an RGB lamp or a red-amber-green traffic lamp. The active regions of both chips can be less than 50 microns away from a heat sink. |
| US08399902B2 |
Light emitting device and method of manufacturing light emitting device
A light emitting device includes a light emitting diode chip, and a first lead terminal in which a bottom portion including a mounting region for the light emitting diode chip is formed, and a side wall continuing to the bottom portion and having an inner surface serving as a reflecting surface for light emitted from the light emitting diode chip is continuously formed. Further, the light emitting device includes a second lead terminal provided to be spaced from the first lead terminal. Furthermore, the light emitting device includes a resin portion which supports the first lead terminal and the second lead terminal, and in which a cavity exposing a portion of the second lead terminal and the mounting region in the first lead terminal is formed. |
| US08399897B2 |
Optical device package
An optical device package includes a substrate having an upper surface, a distal end, a proximal end, and distal and proximal longitudinally extending notches co-linearly aligned with each other. A structure is mounted to the substrate and has at least one recessed portion. The structure can be a lid or a frame to which a lid is bonded. An optical fiber is positioned within at least one of the proximal longitudinally extending notch and the distal longitudinally extending notch and within the recessed portion of the structure mounted to the substrate. The optical device package can also include conductive legs extending upwardly from bonding pads on the upper surface of the substrate to facilitate flip mounting of the optical device package onto a circuit board or other such platform. |
| US08399894B2 |
Semiconductor light emitting device
A wiring electrode is provided on a mount substrate. A light emitting element is provided on the wiring electrode to connect electrically with the wiring electrode and is configured to emit a blue to ultraviolet light. A reflective film is provided above the light emitting element to cover the light emitting element so that a space is interposed between the reflective film and the light emitting element. The reflective film is capable of transmitting the blue to ultraviolet light. A fluorescent material layer is provided above the light emitting element to cover the light emitting element so that the reflective film is located between the fluorescent material layer and the light emitting element. A light from the fluorescent material layer is reflected by the reflective film. |
| US08399893B2 |
Luminous means
A luminous means includes a first group of semiconductor chips and a second group of semiconductor chips, each group includes at least one semiconductor chip, wherein the first and second groups of semiconductor chips are arranged laterally alongside one another at least in part with respect to a main emission direction of the luminous means, and a third group of semiconductor chips which includes at least one semiconductor chip and is disposed downstream of the first and the second group with respect to the main emission direction, wherein each group of semiconductor chips emits electromagnetic radiation in wavelength ranges that differ from one another in pairs, radiation emitted by the third group of semiconductor chips has the shortest-wave wavelength range, radiation emitted by the first and second group of semiconductor chips at least partly passes into the at least one semiconductor chip of the third group, and mixed radiation is emitted by an emission area of the luminous means. |
| US08399891B2 |
Active device array substrate and method for fabricating the same
An active device array substrate and a fabricating method thereof are provided. A first patterned conductive layer including separated scan line patterns is formed on a substrate. Each scan line pattern includes a first and second scan lines adjacent to each other. Both the first and the second scan lines have first and second contacts. An open inspection on the scan line patterns is performed. Channel layers are formed on the substrate. A second patterned conductive layer including data lines interlaced with the first and second scan lines, sources and drains located above the channel layers, and connectors is formed on the substrate. The sources electrically connect the data lines correspondingly. At least one of the connectors electrically connects the first and second scan lines, so as to form a loop in each scan line pattern. Pixel electrodes electrically connected to the drains are formed. |
| US08399890B2 |
Semiconductor light emitting device and light emitting apparatus having thereof
Embodiments relate to a semiconductor light emitting device and a light emitting apparatus comprising the same. The semiconductor light emitting device according to embodiments comprises a plurality of light emitting cells comprising a plurality of compound semiconductor layers; a plurality of ohmic contact layers on the light emitting cells; a first insulating layer on the ohmic contact layer; a second electrode layer electrically connected to a first light emitting cell of the light emitting cells; and a plurality of interconnection layers connecting the light emitting cells in series. |
| US08399889B2 |
Organic light emitting diode and organic solar cell stack
This disclosure relates to an organic solar cell and an organic light emitting diode stack. The stack comprises a solar cell portion having a substrate, an electrode, an active layer, and a second electrode. The stack also comprises a light emitting diode portion having a substrate, an electrode, an active layer, and a second electrode. The solar cell portion is laminated to the light emitting diode portion to form a stack. In a variation, the stack comprises a solar cell portion that includes a substrate, an electrode and an active layer. In this variation, there is a connection portion that includes a second substrate, having, a second electrode on one side and a third electrode on the other side of the second substrate. Also in this variation, there is also a light emitting diode portion, which includes a third substrate, an electrode on the third substrate and a second active layer. The solar cell portion is laminated to the connection portion and the connection portion is laminated to the light emitting diode portion to form a stack. |
| US08399887B2 |
Thin film transistor and manufacturing method thereof
The present invention provides a structure of the TFT in which a current-voltage characteristic can be improved. The present invention refers to a thin film transistor comprising a lamination layer wherein a first conductive film, a first insulating film and a second conductive film are sequentially laminated, a semiconductor film formed so as to be in contact with the side surface of the lamination layer, and a third conductive film covering the semiconductor film through a second insulating film. The first conductive film and the second conductive film are a source electrode and a drain electrode, and a region which is in contact with the first insulating film and the third conductive film is a channel forming region in semiconductor film, and the third conductive film is a gate electrode. |
| US08399885B2 |
Thin film transistor substrate and flat panel display apparatus
A thin film transistor substrate including a plurality of thin film transistors, and a flat panel display apparatus. Each of the plurality of thin film transistors includes an active layer comprising a first channel region having a first plurality of protrusion lines arranged therein and a second channel region and having a second plurality of protrusion lines arranged therein, a source electrode and a drain electrode electrically connected to the active layer and a gate electrode insulated from the active layer, wherein the first and second plurality of protrusion lines extend in a first direction, wherein a edges of the first channel region that extend in the first direction and are offset sideways by a distance in a second direction that is orthogonal to the first direction from corresponding edges of the second channel region that extend in the first direction. |
| US08399882B2 |
Oxide semiconductor transistors and methods of manufacturing the same
Transistors and methods of manufacturing the same. A transistor may be an oxide thin film transistor (TFT) with a self-aligned top gate structure. The transistor may include a gate insulating layer between a channel region and a gate electrode that extends from two sides of the gate electrode. The gate insulating layer may cover at least a portion of source and drain regions. |
| US08399874B2 |
Vertical nonvolatile memory device including a selective diode
Provided are a vertical nonvolatile memory device and a method for fabricating the vertical nonvolatile memory device. The vertical nonvolatile memory device can be integrated more highly as compared with a nonvolatile memory device of the related art. In addition, since the vertical nonvolatile memory device includes a selective diode, reading errors can be prevented. |
| US08399869B2 |
UV luminaire having a plurality of UV lamps, particularly for technical product processing
In various embodiments, a UV luminaire may include a housing which is designed for accommodating a plurality of UV lamps and a protective atmosphere, wherein the housing is subdivided in such a manner into chambers respectively containing some of the UV lamps and can be opened in such a manner that each of the UV lamps can be replaced with detriment to the protective atmosphere only of the respective chamber. |
| US08399860B2 |
Method for preventing deterioration of edible oil or industrial oil and apparatus therefor
A fluororesin-coated electric wire cable is wound around a ring-shaped groove defined by an outer periphery of a cylinder and two flange edges immersed in an edible oil in a tank, forming each oscillating unit having a coil part; and the oscillating units are connected to an electromagnetic wave generator through a relay unit. Electromagnetic waves are irradiated from the coil parts based on an alternating current having a single frequency, an alternating current having a plurality of single frequencies different from one another, or an alternating current having a timewise varying frequency, the alternating currents each being within a frequency band of 4 kHz to 25 kHz, and a treatment based on a far-infrared heater or far-infrared ceramic is used combinedly therewith, to prevent deterioration of an edible oil or industrial oil. |
| US08399855B2 |
Photodiode for detection within molecular diagnostics
A photodiode (200), for instance a PN or a PIN photodiode, is disclosed. The photodiode receives incident radiation having first and second spectral distributions, where the first spectral distribution is spectrally shifted from the second spectral distribution. The photodiode has a first semiconductor layer (211) capable of absorbing incident radiation (231) having a first spectral distribution without generating a photocurrent, while simultaneously transmitting incident radiation having a second spectral distribution to the intrinsic layer (212) for generating a photocurrent (213). The photodiode may be used in connection with detecting the presence of target molecules that has been labeled with labeling agents, such as fluorophores or quantum dots. The labeling agents are characterized by the Stokes shift and, therefore, they emit fluorescent radiation having the second spectral distribution that is spectrally shifted from the illumination radiation having the first spectral distribution. |
| US08399849B1 |
Fast neutron detector
An activation detector for fast-neutrons has a yttrium target exposed to a neutron source. Fast-neutrons which have energy in excess of 1 MeV (above a threshold energy level) generate gamma rays from a nuclear reaction with the yttrium, the gamma rays having an energy level of 908.96 keV, and the resultant gamma rays are coupled to a scintillator which generates an optical response, the optical response of the scintillator is coupled to a photomultiplier tube which generates an electrical response. The number of counts from the photomultiplier tube provides an accurate indication of the fast-neutron flux, and the detector is exclusively sensitive to fast-neutrons with an energy level over 1 MeV, thereby providing a fast-neutron detector which does not require calibration or the setting of a threshold. |
| US08399847B2 |
Ruggedized enclosure for a radiographic device
In one embodiment, a portable X-ray detector assembly is provided comprising a detector array and a housing for the detector array. The housing is provided as a multi-layer structure in which at least one layer improves or increases the structural integrity of other layers of the housing. In certain embodiments, the structural integrity layer also acts to reduce or eliminate electromagnetic interference that might otherwise affect the detector or other electronics in the vicinity of the detector. |
| US08399844B2 |
Detector assembly
A detector made of a detector assembly including a detector housing comprising a reflective interior surface relative to a wavelength of fluoresced electromagnetic radiation, and a scintillator contained within the detector housing. The detector further including a photomultiplier tube (PMT) coupled to the detector housing, wherein a portion of the PMT is contained within the detector housing. |
| US08399842B2 |
Digital radiographic detector with bonded phosphor layer
A digital radiographic detector having a radiation sensing element with a particulate material dispersed within a binder composition, wherein the binder composition includes a pressure-sensitive adhesive, wherein the particulate material, upon receiving radiation of a first energy level, is excitable to emit radiation of a second energy level, either spontaneously or in response to a stimulating energy of a third energy level. There is an array of photosensors, each photosensor in the array energizable to provide an output signal indicative of the level of emitted radiation of the second energy level that is received. The radiation sensing element bonds directly to, and in optical contact with, either the array of photosensors or an array of optical fibers that guide light to the array of photosensors. |
| US08399840B2 |
Rare-earth halide scintillator coated with a light absorber or light reflector
A scintillator material comprises a rare-earth halide coated with a layer comprising a resin and a pigment. In an embodiment, the scintillator material is used in an ionizing-radiation detector, and in particular embodiment, a gamma camera. The layer can adhere well and act as an absorbent or reflector depending on the color of the pigment. |
| US08399839B2 |
Infrared optical gas-measuring device
A first, upper slotted disk (10) and a second, lower slotted disk (20) are arranged as a gas inlet (11) in a gas-measuring device (1). The first, upper slotted disk (10) and the second, lower slotted disk (20) are connected to one another and to a sensor housing (2) via a spacer element (29). The arrangement of the slotted disks (10, 20) in relation to one another is selected to be such that reduced propagation of light of an infrared radiation source (43) through both slotted disks (10, 20) into the measuring environment is achieved. |
| US08399836B2 |
Infrared ray transmissive optical member and manufacturing method thereof, optical device, and optical apparatus
An optical member made of polycrystalline silicon formed from high-purity trichlorosilane as a raw material, and that absorbs and scatters an infrared ray in a wavelength region of 4 μm or less. In the optical member, a ratio A/B between a transmittance A of an infrared ray having a wavelength of 4 μm and a transmittance B of an infrared ray having a wavelength of 10 μm is 0.9 or less, and an average crystal grain size of the polycrystalline silicon is 5 μm or less. This polycrystalline silicon is produced by hydrogen reducing SiHCI3 by heating a base material to 800 to 900° C. using a chemical vapor deposition method. In this way, an infrared ray transmissive optical member, a manufacturing method thereof, an optical device, an infrared detector, and an optical apparatus capable of sensing a human body with high sensitivity and accuracy are realized. |
| US08399830B2 |
Means and method for field asymmetric ion mobility spectrometry combined with mass spectrometry
Analyte ions are analyzed first by field asymmetric ion mobility spectrometry (FAIMS) before being analyzed by a mass analyzer. Analyte ions are produced at near atmospheric pressure and transferred via a dielectric capillary into the vacuum system of the mass analyzer. While passing through the capillary, the ions are analyzed by FAIMS via electrodes on the interior wall of the capillary. Improved ion transmission is achieved by providing smooth geometric transitions between the channel in FAIMS analyzer and the channel in the remainder of the capillary. |
| US08399828B2 |
Merged ion beam tandem TOF-TOF mass spectrometer
A tandem time-of-flight mass spectrometer includes a first pulsed ion source that produces ions with a first mass and charge that directs the ions into a first stage of a tandem TOF mass spectrometer. In addition, a second pulsed ion source produces ions with a second mass and an opposite charge directs the ions into the first stage of the tandem TOF mass spectrometer. A field-free reaction region is positioned in the ion flight path so that ions from first and second pulsed ion source arrive at the entrance of the field-free reaction region substantially simultaneously in at least one of time and space. At least some of the ions from the first and second pulsed ion source are fragmented by ion-ion collision between positive and negative ions. A second stage of the tandem mass spectrometer separates fragment ions produced in the reaction region according to their mass-to-charge ratio. |
| US08399824B2 |
Beam power with multipoint broadcast
A beam power source transmits a signal indicating power availability, receives a request for power in response, and beams power in response to the request. |
| US08399819B2 |
Current source to drive a light source in an optical sensor system
A current source circuit to drive a light source in an optical sensor system is disclosed. The current source includes an inductor connected in series with a resistor, and a diode coupled in parallel with the inductor and resistor. The current source is configured to receive a regulated direct current (DC) voltage and to provide the current through the inductor to the light source when a switch is closed, and to divert current through the inductor to the diode when the switch is open. |
| US08399815B2 |
Apparatus and method for hardening bearing surfaces of a crankshaft
An apparatus and method for hardening the concentric main bearing surfaces and orbital pin bearing surfaces of a crankshaft for an internal combustion engine. The apparatus includes an inductor that is connected to a high frequency power source with a power controller to cause the power source to direct a given power to the inductor at given rotational heating positions of the crankshaft. A master controller creates output signals to control the power controller. The apparatus and method includes a first multi-surface hardening station with inductors for all of the main bearing surfaces, a second multi-surface hardening station with inductors for some of the orbital pins and a third multi-surface hardening station with inductors for the remaining orbital pins. Total indicator run out (TIR) is measured after the first station to adjust the heating process in the third station to produce a straight crankshaft. |
| US08399811B2 |
Stage for substrate temperature control apparatus
A stage for a substrate temperature control apparatus having high reliability at low cost by preventing thermal deformation of a plate while employing a material other than ceramics as a material of the plate. The stage is used for mounting a substrate in the substrate temperature control apparatus for controlling a temperature of the substrate, and the stage includes: a plate having a first surface facing the substrate and a second surface opposite to the first surface; and a planar heater bonded to the second surface of the plate, wherein surface treatment is performed in a first thickness on the first surface of the plate, and the surface treatment is performed in a second thickness thinner than the first thickness or no surface treatment is performed on a predetermined area of the second surface of the plate. |
| US08399810B2 |
Electric patio bistro
A grilling apparatus comprising: a base housing; a cooking grate positionable on or in an upper portion of the base housing; a radiant heat cavity within the base housing below the cooking grate; at least one electric heating element within the radiant heat cavity; and a reflective surface within the radiant heat cavity which diverges outwardly in an upward direction at an angle of from 20° to 60° from horizontal. |
| US08399809B1 |
Load chamber with heater for a disk sputtering system
A disk processing system having a plurality of processing chambers, a load chamber comprising a heater, and a disk transport system coupled to the plurality of processing chambers and the load chamber to transport a disk there among. |
| US08399808B2 |
Systems and methods for forming a time-averaged line image
Systems and methods for forming a time-average line image are disclosed. The method includes forming a line image with a first amount of intensity non-uniformity. The method also includes forming and scanning a secondary image over at least a portion of the line image to form a time-averaged modified line image having a second amount of intensity non-uniformity that is less than the first amount. Wafer emissivity is measured in real time to control the intensity of the secondary image. Temperature is also measured in real time based on the wafer emissivity and reflectivity of the secondary image, and can be used to control the intensity of the secondary image. |
| US08399807B2 |
Glow plug and method for manufacturing the same
The present invention provides a glow plug capable of preventing a deformation or eccentricity of the coil, thereby improving a durability of the coil and preventing a variation in temperature-rising characteristic. Also, the present invention provides a method for manufacturing the glow plug. |
| US08399806B2 |
Built-in type cooker
Provided is a built-in type cooker including a heat dissipation part connected to an electronic component and exposed to the outside of the cabinet. The built-in type cooker include a cabinet having an upwardly opened polyhedral shape, a top plate covering a top surface of the cabinet, the electronic component installed within the cabinet, and the heat dissipation part in which at least portion thereof is exposed to the side of the cabinet, the heat dissipation part being connected to the electronic component. |
| US08399805B2 |
Anti-fogging device and anti-fogging viewing member
An anti-fogging device has a substantially transparent or optically clear plastic layer with a heater element formed of etched metallic foil bonded to it. The device has an adhesive element disposed at the periphery of the device for sticking to a viewing member such as a motorcycle helmet visor, surgical mask or rear windscreen for a convertible car, to leave a gap between the heater element and the viewing member. |
| US08399804B2 |
Method for manufacturing prismatic battery, and laser welding jig and laser welding device for manufacturing the same
A laser welding device for manufacturing a prismatic battery 10 of the invention has a pair of jigs 12A, 12B for securing a prismatic battery outer can B1, a gas supply section for supplying inert gas to welding points of a sealing cover B2 fitted to the prismatic battery outer can B1, and a laser unit 11 for irradiating laser beam. Each of the jigs 12A, 12B is provided with a slit-shaped blower outlet and the blower outlet is positioned below the welding points. The inert gas is supplied to the blower outlet from the gas supply section and is blown from the blower outlet to the welding points from below. The laser welding device for manufacturing a prismatic battery 10 can obtain a laser welding device that welds the sealing cover B2 fitted to the prismatic battery outer can B1 fast, preventing weld droops and allowing uniform welding. |
| US08399799B2 |
Method for manufacturing spark plug
A method for manufacturing a spark plug is a method for manufacturing the spark plug having an electrode base member and a noble metal tip welded thereto by means of a laser or an electrode base member, a tip base member joined thereto, and a noble metal tip welded to the tip bases material by means of a laser, and the method includes a laser welding process of welding the electrode base member or the tip base member to the noble metal tip by means of a laser and through use of a laser beam whose BBP value assumes 25 mm·mrad (a radius·a half angle) or less at a time point when a laser beam enters a transfer optical system for guiding the laser beam to areas to be welded where laser welding is to be performed. |
| US08399793B2 |
Methods and materials for hard-facing
In a hard facing process, a core material is applied to the base material of an article, which may incorporate metal components. An additive is introduced into a molten puddle generated by the hard facing process. The additive functions to increase the wear resistant capabilities of the hard faced article. In one embodiment, the additive comprises mineral particulates, which may consist of diamond granules. |
| US08399792B2 |
Welding device and method
A welding device includes an electrode head adapted to concurrently house an array of associated multiple, continuous-feed electrodes in a spaced apart configuration for concurrently depositing cladding material on the surface of a workpiece. The electrode head may be actuatable through a welding trajectory. The welding device may also include a welding power source adapted to provide power for simultaneously establishing a welding arc between each of the multiple, continuous-feed electrodes and the workpiece. |
| US08399790B1 |
Methods and systems for recovering alluvial gold
Various embodiments of methods and systems are provided for mining alluvial gold deposits. The methods can comprise collecting feed from alluvium and washing the feed at high pressure. The feed can be separated into a plurality of separate fractions. At least one fraction is transferred to a metal sensor system using a conveyer, wherein when gold is detected in a piece of the fraction, an air blast can be targeted and delivered at the piece, with the air blast diverting the piece to a receiving container. |
| US08399787B2 |
Switch lever for vehicle
A switch lever for a vehicle including: knobs that perform a rotation manipulation in order to turn on, turn on or off a light of a vehicle, or to adjust a wiping interval of a windshield wiper of the vehicle; a pair of lever arms that are disposed within and rotate with the knobs according to a rotation of the knobs; a pair of contact terminals each that is installed at an end part of one side of the lever arms to move according to a rotation of the lever arms; a guide member having guide grooves for receiving the pair of contact terminals therein; and an insulation part having a fixed terminal that contacts with each of the contact terminals to generate an operation signal. |
| US08399782B2 |
Variable proportionate beam scale for proportioning baking recipes
A pivot assembly (24) is movably connected to a balance beam (22) between a first and second balancing area (34, 36). The pivot assembly (24) defines a pivot axis (B) being movable relative to a center axis (A0) to define a first variable pivot distance (Pd1) and a second variable pivot distance (Pd2) for proportioning a first and second component according to the concurrently and inversely variable first and second pivot distances (Pd1, Pd2). The balance beam (22) presents a proportioning scale (60) which includes a plurality of identical ratios (62) in scale of the first variable pivot distance (Pd1) to the second variable pivot distance (Pd2) for aligning the pivot assembly (24) with a desired ratio of the first and second components. A first and second pair of retainer walls (38, 40) extend upwardly from the respective balancing areas (34, 36) and diverge from one another for abutting and centering a variety of container sizes on the respective balancing areas (34, 36). |
| US08399781B1 |
Anti-tamper mesh
An electronic device includes at least one terminal formed on the electronic device. The electronic device also includes at least one of a semiconductor device, an integrated circuit chip, and a computer. A seamless conductive mesh is formed on at least one surface of the electronic device. The conductive mesh is in electrical contact with the terminal. The terminal facilitates electrical conduction between the conductive mesh and an electrical detection circuit. The electronic device also may include a pattern having traces formed on at least two surfaces where each of the traces includes a continuous loop of conductive material is formed on at least two surfaces. The electronic device also may include a first plurality of conductive loops formed on the electronic device that are continuous and surround the electronic device in a first direction and a second plurality of conductive loops formed on the electronic device that are continuous and surround the electronic device in a second direction. |
| US08399779B2 |
Wiring board and method of manufacturing the same
A wiring board includes a pad exposed from an opening portion of an outermost insulating layer. The pad includes: a first metal layer a surface of which is exposed from the wiring board; a second metal layer provided on the first metal layer and formed of a material effective in preventing a metal contained in a via inside the board from diffusing into the first metal layer; and a third metal layer provided between the second metal layer and the via, and formed of a material harder to be oxidized than that of the second metal layer. The thickness of the third metal layer is relatively thick, and is preferably selected to be three times or greater than a thickness of the second metal layer. A side surface of the third metal layer and a surface of the third metal layer to which the via is to be connected are roughed. |
| US08399776B2 |
Substrate having single patterned metal layer, and package applied with the substrate , and methods of manufacturing of the substrate and package
A substrate having single patterned metal layer includes a patterned base having at least a plurality of apertures, the patterned metal layer disposed on the patterned base, and a first surface finish layer. Parts of the lower surface of the patterned metal layer are exposed by the apertures of the patterned base to form a plurality of first contact pads for downward electrical connection externally, and parts of the upper surface of the patterned metal layer function as a plurality of second contact pads for upward electrical connection externally. The first surface finish layer is disposed at least on one or more surfaces of the second contact pads, and the first surface finish layer is wider than the second contact pad beneath. A package applied with the substrate disclosed herein further comprises at least a die conductively connected to the second contact pads of the substrate. |
| US08399775B2 |
Flex-rigid wiring board and method of manufacturing the same
A flex-rigid wiring board includes a first rigid substrate, a second rigid substrate arranged at a distance from the first rigid substrate to provide a space between the first and second rigid substrates and a flexible substrate. The flexible substrate includes a first tip portion connected to the first rigid substrate, and a second tip portion connected to the second rigid substrate such that the first and second rigid substrates are connected to each other by way of the flexible substrate. At least one bending portion is formed between the first and second tip portions of the flexible substrate, each of the at least one bending portions is provided in the space between the first and second rigid substrates. |
| US08399773B2 |
Substrates having voltage switchable dielectric materials
Various aspects provide for incorporating a VSDM into a substrate to create an ESD-protected substrate. In some cases, a VSDM is incorporated in a manner that results in the ESD-protected substrate meeting one or more specifications (e.g., thickness, planarity, and the like) for various subsequent processes or applications. Various aspects provide for designing a substrate (e.g., a PCB) incorporating a VSDM, and adjusting one or more aspects of the substrate to design a balanced, ESD-protected substrate. Certain embodiments include molding a substrate having a VSDM layer into a first shape. |
| US08399771B2 |
Visual latching indicator arrangement for an electrical bushing and terminator
An elbow terminator has a socket in which an electrical probe is disposed. The terminator is insertable onto an electrical bushing such that a tongue of the bushing is received in the socket of the terminator, and the probe of the terminator is electrically coupled to a contact sleeve disposed within the tongue. A latching mechanism produces positive latching between the tongue and socket when the tongue has been inserted to a predescribed depth within the socket. In order to enable an operator to visually observe that the tongue has been inserted to the prescribed depth, the bushing carries a color band which becomes completely disposed (invisible) in the socket when positive latching occurs. Alternatively, the bushing can be provided with gauge tabs which become aligned with a witness line formed on the terminator when positive latching occurs. |
| US08399762B2 |
Electrical feed-through
The present invention provides an electrical feed-through (200) for making a durable and reliable electrical connection through a wall (227) of a vacuum chamber (225). The electrical feed-through (200) comprises a tubular member having an open end (217) and a closed end (219). At least one conductor (201) extends through the closed end (217) and is fixed thereto by a vacuum sealing joint (214). The joint (214) is arranged so that it is not in line-of-sight from the open end (217). In this way impinging elements (220) and direct heat radiation (221) is prevented from directly reaching the joint (214), thereby extending the time it takes for contamination of the joint (214) to cause problems. |
| US08399754B2 |
Musical instrument with a head tensioned over a shell by a rim using an axially oriented grain structure
A musical instrument comprising a shell and a rim for tensioning a head across an open end of the shell, for example a drum, is improved by forming one or both of the shell and the rim using a primary material having an axially oriented grain structure together with an auxiliary layer of secondary material having greater hoop strength than the primary material. The primary material can be a natural plant material, such as hardwood with the naturally occurring grain structure being oriented in an axial direction by assembling the annular rim using a stave construction. The secondary material can comprises a composite material including carbon fiber to reinforce the stave construction. |
| US08399753B2 |
Slide for use with fretted instruments
A tubular shaped slide having first and second spaced ends for use with a fretted musical instrument, the first end having a diameter greater than the second end. The slide is positioned on the finger of a wearer such that the wearer's fingertip extends beyond the second end of the slide; the second end of the slide being formed at an angle to the vertical. A sizing slot extends along the length of the slide. |
| US08399747B1 |
Soybean cultivar 1446437
A soybean cultivar designated 1446437 is disclosed. The invention relates to the seeds of soybean cultivar 1446437, to the plants of soybean cultivar 1446437, to the plant parts of soybean cultivar 1446437, and to methods for producing progeny of soybean cultivar 1446437. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 1446437. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 1446437, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 1446437 with another soybean cultivar. |
| US08399744B2 |
Soybean variety A1023486
The invention relates to the soybean variety designated A1023486. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1023486. Also provided by the invention are tissue cultures of the soybean variety A1023486 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1023486 with itself or another soybean variety and plants produced by such methods. |
| US08399743B2 |
Soybean variety A1024305
The invention relates to the soybean variety designated A1024305. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1024305. Also provided by the invention are tissue cultures of the soybean variety A1024305 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1024305 with itself or another soybean variety and plants produced by such methods. |
| US08399742B2 |
Squash hybrid PX 13067464
The invention provides seed and plants of squash hybrid PX 13067464 and the parent lines thereof. The invention thus relates to the plants, seeds and tissue cultures of squash hybrid PX 13067464 and the parent lines thereof, and to methods for producing a squash plant produced by crossing such plants with themselves or with another squash plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants. |
| US08399740B2 |
Cucumber hybrid ‘corinto’
A hybrid cucumber designated ‘Corinto’ is disclosed having resistance to powdery mildew (Sphaerotheca fuliginea), cucumber mosaic virus and cucumber vein yellowing virus. The invention relates to the seeds of hybrid cucumber ‘Corinto,’ to the plants of hybrid cucumber ‘Corinto’ and to methods for producing a cucumber plant, either inbred or hybrid, by crossing the hybrid ‘Corinto’ with itself or another cucumber plant. The invention further relates to methods for producing a cucumber plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other cucumber lines, cultivars or hybrids derived from the hybrid cucumber ‘Corinto.’ |
| US08399738B2 |
Fructan biosynthetic enzymes
This invention relates to isolated nucleic acid fragments encoding fructosyltransferases. More specifically, this invention relates to polynucleotides encoding 1-FFTs, 6-SFTs, or 1-SSTs. The invention also relates to the construction of a recombinant DNA constructs encoding all or a portion of the fructosyltransferases, in sense or antisense orientation, wherein expression of the recombinant DNA construct results in production of altered levels of the fructosyltransferases in a transformed host cell. |
| US08399734B1 |
Maize variety hybrid X8K869
A novel maize variety designated X8K869 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X8K869 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X8K869 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X8K869, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X8K869. This invention further relates to methods for producing maize varieties derived from maize variety X8K869. |
| US08399732B2 |
Adhesive patch
An adhesive patch configured to attach an ostomy appliance to a patient includes a peripheral rim disposed around a central hole that is attachable to a stoma of the patient; and a band of adhesive extending from the peripheral rim to an inner border of the adhesive patch and having a pattern of curvilinear indentations extending to the peripheral rim of the patch. |
| US08399726B2 |
Reactors and processes for the oxidative coupling of hydrocarbons
A method for the oxidative coupling of hydrocarbons includes providing an oxidative catalyst inside a reactor and carrying out the oxidative coupling reaction under a set of reaction conditions. The reactor surfaces that contact the reactants and products do not provide a significant detrimental catalyzing effect. In an embodiment the reactor contains an inert lining or a portion of the reactor inner surface is treated to reduce the detrimental catalytic effects. In an embodiment the reactor contains a lining that includes an oxidative catalyst. |
| US08399718B2 |
Promoted copper/zinc catalyst for hydrogenating aldehydes to alcohols
A catalyst for hydrogenating aldehydes to alcohols includes a combination of copper oxide and zinc oxide and promoters including one or more alkaline earth metal promoters and/or one or more transition metal promoters. The promoters may be combined with copper oxide and zinc oxide after formation of a copper/zinc precursor material. |
| US08399714B2 |
Process for the synthesis of polyhydroxystilbene compounds
The invention relates to a process for the synthesis of stilbene derivatives of formula (I)-(E) or (I)-(Z) in which R represents hydrogen or an OH group, by deprotection in the presence of an aluminum halide and of a tertiary amine of a compound of formula (II)-(E) or (II)-(Z) in which A represents hydrogen or an OR′1 group, and R1, R2, R3 and R′1 independently represent an alkyl or aralkyl group. |
| US08399713B2 |
Alkyl perfluoroalkene ethers
Disclosed are compositions comprising a compound having the formula CF3(CF2)xCF═CFCF(OR)(CF2)yCF3, wherein R is CH3 or C2H5 or mixtures thereof, and wherein x and y are independently 0, 1, 2 or 3, and wherein x+y=1, 2 or 3. Also disclosed are unsaturated fluoroethers selected from the group consisting of CF3(CF2)xCF═CFCF(OR)(CF2)yCF3, CF3(CF2)xC(OR)═CFCF2(CF2)yCF3, CF3CF═CFCF(OR)(CF2)x(CF2)yCF3, CF3(CF2)xCF═C(OR)CF2(CF2)yCF3, and mixtures thereof, wherein R can be either CH3, C2H5 or mixtures thereof, and wherein x and y are independently 0, 1, 2 or 3, and wherein x+y=0, 1, 2 or 3. Also disclosed herein are novel methods of using a composition comprising at least one of the compounds described above as novel solvents, carrier fluids, dewatering agents, degreasing solvents or defluxing solvents. |
| US08399712B2 |
Pterostilbene cocrystals
Cocrystals of pterostilbene are disclosed, including: pterostilbene:caffeine cocrystal, pterostilbene:carbamazepine cocrystal, pterostilbene:glutaric acid cocrystal, and pterostilbene:piperazine cocrystal. The pterostilbene:caffeine cocrystal is polymorphic. Forms I and II of the pterostilbene:caffeine cocrystal are disclosed. The therapeutic uses of the pterostilbene cocrystals and of pharmaceutical/nutraceutical compositions containing them are also disclosed. The disclosure sets out various methods of making and characterizing the pterostilbene cocrystals. |
| US08399709B2 |
Method for the sulfonylation of a hydroxylated organic compound
The subject of the present invention is a method for the sulphonylation of a hydroxylated organic compound. The invention relates more particularly to a method for the trifluoromethanesulphonylation of a hydroxylated organic compound. The invention is especially intended for perfluorinated aliphatic hydroxylated compounds. The method of the invention for the sulphonylation of a hydroxylated organic compound is characterized in that it comprises reacting said compound with a sulphonylation agent in an organic medium and in the presence of a heterogeneous inorganic base. |
| US08399708B2 |
Compounds useful for treating bipolar disorders
The invention relates to the use of valnoctamide (VCD) for the treatment of bipolar disorder and in particular for the treatment of the manic phase of the bipolar disorder. |
| US08399706B2 |
Chiral tetraaminophosphonium salts, catalyst for asymmetric synthesis and method for producing chiral β-nitroalcohol
A chiral tetraaminophosphonium salt represented by formula (1) and a method for producing chiral β-nitroalcohol comprising reacting an aldehyde or a ketone and a nitroalkane in the presence of the chiral tetraaminophosphonium salt represented by formula (1) and a base, or in the presence of a conjugated base of the chiral tetraaminophosphonium salt represented by formula (1): wherein R1 to R4 are independently a hydrogen atom or a monovalent hydrocarbon group; and, R1 and R2 are different groups or R3 and R4 are different groups. |
| US08399705B2 |
Alkali metal salt of glutamic acid N,N-diacetic acid, a process to prepare such salt, and the use thereof
The present invention relates to an alkalimetal salt of glutamic acid-N,N-diacetic acid (GLDA) of the formula NaxKyHzGLDA, wherein x is equal to or more than 2 and lower than 4 and y is more than 0 and equal to or lower than 2, x+y is 3.5-4, and x+y+z=4, to processes to prepare such salt and the use thereof. |
| US08399704B2 |
Methods for salt production
The present invention provides methods to produce arginine bicarbonate more rapidly and efficiently than conventional methods. |
| US08399697B2 |
Process for preparing polyol esters
The present invention relates to a process for preparing polyol esters by reacting polyols with linear or branched aliphatic monocarboxylic acids having 3 to 20 carbon atoms in the presence of an adsorbent and subsequent steam treatment in the course of workup of the crude ester. |
| US08399695B2 |
Organometallic precursor compounds
This invention relates to organometallic precursor compounds represented by the formula (H)mM(R)n wherein M is a metal or metalloid, R is the same or different and is a substituted or unsubstituted, saturated or unsaturated, heterocyclic radical containing at least one nitrogen atom, m is from 0 to a value less than the oxidation state of M, n is from 1 to a value equal to the oxidation state of M, and m+n is a value equal to the oxidation state of M, a process for producing the organometallic precursor compounds, and a method for producing a film or coating from the organometallic precursor compounds. |
| US08399690B2 |
4,5-dihydro-6-oxa-3-thia-1-aza-benzo[e]azulene compounds
Benzopyran and benzoxepin compounds of Formulas I and II, and including stereoisomers, geometric isomers, tautomers, solvates, metabolites and pharmaceutically acceptable salts thereof, are useful for inhibiting lipid kinases including p110 alpha and other isoforms of PI3K, and for treating disorders such as cancer mediated by lipid kinases. Methods of using compounds of Formulas I and II for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed. |
| US08399688B2 |
Production of levulinic acid, furfural, and gamma valerolactone from C5 and C6 carbohydrates in mono- and biphasic systems using gamma-valerolactone as a solvent
A method to make levulinic acid (LA), furfural, or gamma-valerolactone (GVL). React cellulose (and/or other C6 carbohydrates) or xylose (and/or other C5 carbohydrates) or combinations thereof in a monophasic reaction medium comprising GVL and an acid; or (ii) a biphasic reaction system comprising an organic layer comprising GVL, and a substantially immiscible aqueous layer. At least a portion of the cellulose (and/or other C6 carbohydrates), if present, is converted to LA and at least a portion of the xylose (and/or other C5 carbohydrates), if present, is converted into furfural. |
| US08399687B2 |
Processes for the production of hydrogenated products
A process for making a hydrogenated product includes providing a clarified DAS-containing fermentation broth, distilling the broth to form an overhead that includes water and ammonia, and a liquid bottoms that includes MAS, at least some DAS, and at least about 20 wt % water, cooling and/or evaporating the bottoms, and optionally adding an antisolvent to the bottoms, to attain a temperature and composition sufficient to cause the bottoms to separate into a DAS-containing liquid portion and a MAS-containing solid portion that is substantially free of DAS, separating the solid portion from the liquid portion, recovering the solid portion, hydrogenating the second solid portion in the presence of at least one hydrogenation catalyst to produce the hydrogenated product comprising at least one of THF, GBL or BDO, and recovering the hydrogenated product. |
| US08399685B2 |
Process for producing thiophene compound and intermediate thereof
To provide a novel process for producing a 2-aryl-3-hydroxy-4-substituted carbonyl thiophene compound or an intermediate thereof useful as an intermediate for production of medicines and agricultural chemicals.A 2-aryl acetate compound represented by the formula (1): wherein R1 is an aryl group or the like, R4 is a C1-3 alkyl group or the like, and X is a leaving group, is reacted with a thioacetic acid compound to form a thioacetyl compound (3), the thioacetyl compound (3) is reacted with a vinyl ketone compound to form a γ-ketosulfide compound (5), which is cyclized under basic conditions to form a dihydrothiophene compound (6), and the dihydrothiophene compound (6) is oxidized by using an oxidizing agent to produce a 2-aryl-3-hydroxy-4-substituted carbonyl thiophene compound (7). |
| US08399684B2 |
Sulfonamide-based organocatalysts and method for their use
Organocatalysts, particularly proline sulfonamide organocatalysts, having a first general formula as follows are disclosed. Embodiments of a method for using these organocatalysts also are disclosed. The method comprises providing a disclosed organocatalyst, and performing a reaction, often an enantioselective or diastereoselective reaction, using the organocatalyst. Solely by way of example, disclosed catalysts can be used to perform aldol reactions, conjugate additions, Michael additions, Robinson annulations, Mannich reactions, α-aminooxylations, α-hydroxyaminations, α-aminations and alkylation reactions. Certain of such reactions are intramolecular cyclizations used to form cyclic compounds, such as 5-or 6-membered rings, having one or more chiral centers Disclosed organocatalysts generally are much more soluble in typical solvents used for organic synthesis than are known compounds. Moreover, the reaction yield is generally quite good with disclosed compounds, as is their enantioselective and diastereoselective effectiveness. |
| US08399683B2 |
IAP inhibitors
The present invention describes compounds, processes for their preparation, pharmaceutical compositions containing them, and their use in therapy. |
| US08399682B2 |
Substituted (pyrazolylcarbonyl)imidazolidinones and their use
The present invention relates to novel substituted (pyrazolylcarbonyl)imidazolidinones, methods for their preparation, their use for the treatment and/or prophylaxis of diseases, as well as their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of retroviral diseases, in humans and/or animals. |
| US08399677B2 |
Method for the preparation of fentanyl
The invention provides a method for the preparation of fentanyl comprising: (a) reacting 4-piperidone hydrochloride monohydrate with aniline in presence of reducing environment to produce 4-anilinopiperidine (4-AP), (b) reacting the 4-AP as obtained from step (a) with phenethyl halide under reflux conditions in highly alkaline medium to give 4-anilino-N-phenethylpiperidine, and (c) converting the 4-anilino-N-phenethylpiperidine to fentanyl by reacting with propionyl chloride in presence of halogenated hydrocarbons, then isolating fentanyl by solvent extraction and purifying by crystallization from petroleum ether at a temperature ranging from 60-80° C. |
| US08399676B2 |
Piperidine derivatives
Compounds of formula (I) as well as pharmaceutically acceptable salts thereof can be used in the form of pharmaceutical compositions, wherein A1, A2, R1, R2, R3 and R4 have the significance given in claim 1. |
| US08399674B2 |
Quinolines
The present invention relates to 2-aminoquinolines of formula I wherein R1, R2 and R3 are as defined in the specification, as 5-HT5A receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use for the treatment of CNS disorders. |
| US08399667B2 |
4-anilino quinazoline derivatives as antiproliferative agents
The invention concerns quinazoline derivatives of Formula (I) wherein each of Q1, Z, R1 and Q2 have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours which are sensitive to inhibition of erbB receptor tyrosine kinases. |
| US08399652B2 |
Primers and probes for detecting genital HPV genotypes
The invention relates to oligonucleotides, which are suited as primers for amplifying DNA of genital human papilloma viruses (HPV), to oligonucleotides, which are suited for use as probes for typifying genital HPV genotypes, to methods for amplifying the DNA of genital human papilloma viruses (HPV), to methods for detecting and/or identifying genital HPV genotypes, to nucleotide microarrays containing the oligonucleotides, to kits and to the use of the oligonucleotides for amplifying or typifying genital HPV genotypes, for the diagnosis and/or early diagnosis of diseases and for producing agents for diagnosing diseases. |
| US08399651B2 |
Nucleic acids encoding GAS57 mutant antigens
The invention provides mutants of GAS57 (Spy0416) which are unable to cleave IL-8 and similar substrates but which still maintain the ability to induce protection against S. pyogenes. The invention also provides antibodies which specifically bind to GAS57 and which inhibit its ability to cleave IL-8 and similar substrates. The mutants are useful, inter alia, in vaccine compositions to induce protection against S. pyogenes. The antibodies are useful, e.g., as therapeutics for treating S. pyogenes infections. |
| US08399647B2 |
Alpha5-beta1 antibodies and their uses
The present disclosure provides isolated monoclonal antibodies, particularly human monoclonal antibodies, or antigen binding portions thereof, that specifically bind to integrin α5β1 with high affinity. Nucleic acid molecules encoding the antibodies of the disclosure, expression vectors, host cells and methods for expressing the antibodies of the disclosure are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies or antigen binding portions thereof are also provided. The disclosure also provides methods for treating various cancers using the anti-α5β1 antibodies or antigen binding portions thereof described herein. |
| US08399645B2 |
Chimeric receptors with 4-1BB stimulatory signaling domain
The present invention relates to a chimeric receptor capable of signaling both a primary and a co-stimulatory pathway, thus allowing activation of the co-stimulatory pathway without binding to the natural ligand. The cytoplasmic domain of the receptor contains a portion of the 4-1BB signaling domain. Embodiments of the invention relate to polynucleotides that encode the receptor, vectors and host cells encoding a chimeric receptor, particularly including T cells and natural killer (NK) cells and methods of use. |
| US08399643B2 |
Nucleic acids encoding hyperactive PiggyBac transposases
The present invention provides PiggyBac transposase proteins, nucleic acids encoding the same, compositions comprising the same, kits comprising the same, non-human transgenic animals comprising the same, and methods of using the same. |
| US08399642B2 |
Isolated genomic polynucleotide fragments from the p15 region of chromosome 11 encoding human ribosomal protein L26 (RIBO26)
Provided herein are isolated genomic polynucleotide fragments from the from the p15 region of chromosome 11 encoding human ribosomal protein L26 (RIBO26) and methods of use. |
| US08399639B2 |
Isolated genomic polynucleotide fragments from the p15 region of chromosome 11 encoding human achaete-scute homolog 2 (HASH2)
Provided herein are isolated genomic polynucleotide fragments from the p15 arm of chromosome 11 encoding HASH2 and methods of use. |
| US08399636B2 |
Purification of a triple helix formation with an immobilized obligonucleotide
A method for double-stranded DNA purification, by which a solution containing DNA in a mixture with other components is passed over a support on which is covalently coupled an oligonucleotide capable of hybridizing with a specific sequence present on the DNA to form a triple helix. |
| US08399626B2 |
Antibodies against human angiopoietin 2
The present invention relates to antibodies against human Angiopoietin 2 (anti-ANG-2 antibodies), methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof. |
| US08399622B2 |
Reagents and methods for use in cancer diagnosis, classification and therapy
Methods and reagents for classifying tumors and for identifying new tumor classes and subclasses. Methods for correlating tumor class or subclass with therapeutic regimen or outcome, for identifying appropriate (new or known) therapies for particular classes or subclasses, and for predicting outcomes based on class or subclass. New therapeutic agents and methods for the treatment of cancer. |
| US08399616B2 |
Fusion protein having luminescence activity
The fusion protein comprising (1) a first region comprising the amino acid sequence of SEQ ID NO: 18 and (2) a second region comprising an amino acid sequence for a polypeptide containing at least one cysteine residue for binding to other useful compound via the thiol group can be modified by chemical modification, and thus has a high catalytic ability for a luminescence activity and is highly available for general purposes. |
| US08399610B2 |
HPV vaccine comprising peptides from host cell proteins
The present invention relates to an immunogenic composition for a human papillomavirus (HPV) vaccine that comprises BAX peptides from BAX host cell proteins and more particularly, a vaccine including those peptides that is directed against cancers that are associated with HPV infections, such as cervical cancer, head and neck cancer and skin cancers. The BAX peptides comprise fragments of BAX host cell proteins that have been targeted for degradation by HPV proteins, such as E6 and E7 and are presented on the surface of HPV infected cells in relatively large amounts. These peptides can be recognised by CTL and elicit an immune response, and are therefore ideal tumour-specific markers. The invention also relates to novel peptide: peptide complexes such as BAX peptide/HLA complexes and their use in a tumour-specific vaccine. |
| US08399609B2 |
Treating or preventing extracellular matrix build-up
A method of treatment for treating, preventing, inhibiting or reducing extracellular matrix build-up in a body tissue or a bodily fluid transport vessel, in a subject, includes administering to a subject in need of such treatment an effective amount of a composition including a peptide agent including amino acid sequence LKKTET, a conservative variant thereof, or a peptide agent that stimulates production of an LKKTET peptide, or a conservative variant thereof, in the tissue. |
| US08399602B2 |
Polymerisation reactor, polymerisation device, method for producing bio-degradeable polyester and uses
The present invention relates to a polymerization reactor for continuous polymerization, the reactor being constructed in two stages and comprising a prepolymerization stage which is configured as a stirred vessel or as a loop-type bubble column and also a main polymerization stage which is configured as a tubular reactor. Furthermore, the present invention relates to a method for the production of biodegradable polyester, in particular polylactide, the reactor according to the invention being used. Likewise, the invention relates to a polymerization device which comprises further components in addition to the polymerization reactor. |
| US08399600B2 |
Preparation of low molecular weight polylysine and polyornithine in high yield
The present invention generally relates to the large-scale (e.g., greater than 1 kg scale) preparation of low molecular weight polylysine or polyornithine in high yield by preparing a polylysine or polyornithine having a weight average molecular weight from about 12,500 Daltons to about 22,000 Daltons and hydrolyzing it to produce a polylysine or polyornithine having a weight average molecular weight from about 5,500 Daltons to about 12,000 Daltons. In preferred embodiments, the polymer is a homopolymer of poly-L-lysine. |
| US08399599B2 |
Method and apparatus for processing of plastic material
The invention relates to an apparatus and a method for the processing of plastic material, with a receptacle or cutter-compactor (1) into which the material to be treated can be introduced, in the lower region of which a discharge opening (10) is provided, through which the processed material can be ejected from the receptacle (1), for example into an extruder (11). According to the invention, the receptacle (1) is divided into at least two chambers (6a, 6b, 6c, . . . ) separated from each other by an intermediate base (2′, 2″, . . . ), wherein at least one mixing or comminution tool (7a, 7b, 7c, . . . ) is arranged which acts upon the material in each chamber (6a, 6b, 6c, . . . ), with which the material can be converted into a softened but permanently lumpy or particle-shaped and not melted state and wherein means (5′, 5″, . . . ) are provided which effect or permit an exchange or a transfer of the softened, lumpy, not melted material between each directly adjacent chamber (6a, 6b, 6c, . . . ). |
| US08399598B2 |
Copolycarbonate and process for producing the same
The object of this invention is to provide a copolycarbonate that is excellent in heat resistance, thermal stability and moldability and that uses a renewable resource as a raw material. This invention is a copolycarbonate including 50 to 99 mol % of a carbonate constituent unit (1) of the following formula and 50 to 1 mol% of a carbonate constituent unit (2) derived from an aliphatic diol having a boiling point of 180° C. or higher under reduced pressure of 4×10−3 MPa. |
| US08399597B2 |
Phenolic resin formulation and coatings for abrasive products
A resorcinol-modified phenolic resin composition is formed by reacting a basic catalyst, formaldehyde, water and a benzene-ol to form an intermediate composition to which resorcinol is subsequently added to reduce the presence of free formaldehyde. Optionally, an alkanolamine can be combined and reacted with the resorcinol-modified phenolic resin composition to form a resorcinol-alkanolamine-modified phenolic resin composition. The resorcinol-modified phenolic resin and the resorcinol-alkanolamine-modified phenolic resin compositions can be employed to coat abrasive products having a relatively low free formaldehyde content. |
| US08399596B2 |
Epoxy resin compositions and process for preparing them
The preparation of epoxy resin compositions which comprise glycidyl ethers comprising cyclohexyl groups and have a low oligomer content is carried out by distillation of compositions which are obtainable by ring hydrogenation of compounds of the general formula (I) where —X— is —CR2—, —CO—, —O, —S—, —SO2—, the radicals R are each, independently of one another, H, C1-6-alkyl, C3-6-cycloalkyl, in which one or more H atoms can be replaced by halogen, the radicals R′ are each, independently of one another, C1-4-alkyl, halogen, the indices n are each, independently of one another, 0, 1, 2 or 3, and subsequent reaction of the hydroxyl groups with epichlorohydrin, in thin film evaporators or short path evaporators at a temperature in the range from 150 to 270° C. and a pressure in the range from 0.001 to 1 mbar. |
| US08399595B2 |
Two part polyurethane curable composition having substantially consistent G-modulus across the range of use temperatures
The invention is a two part composition comprising: A. an isocyanate functional group containing component comprising one or more polyisocyanates and one or more isocyanate functional group containing prepolymers having in its backbone the residue of one or more chains derived from polypropylene oxide, copolymers of ethylene oxide and propylene oxide or mixtures thereof wherein equivalent weight of the chains are predominantly about 780 or greater; B. an isocyanate reactive component comprising one or more polypropylene oxide, copolymers of ethylene oxide and propylene oxide or mixtures thereof having equivalent weights predominantly about 960 or greater and terminal groups which are reactive with isocyanate groups; C. one or more low molecular weight compounds having two or more isocyanate reactive groups and a molecular weight of 120 or less wherein the low molecular weight compounds are present as a residue in the isocyanate functional group containing prepolymer, as a component of the isocyanate reactive component or both; D. one or more catalysts for the reaction of isocyanate functional groups with isocyanate reactive groups wherein the catalyst may be located in the isocyanate functional group containing component or the isocyanate reactive component. |
| US08399593B2 |
Polymer, and composition and film including the same
A polymer including a structure represented by the following Chemical Formula 1, and a composition and a film including the same are provided. In the above Chemical Formula 1, each substituent is as defined in the detailed description. |
| US08399591B2 |
Amino-mercapto functional organopolysiloxanes
An organopolysiloxane containing both an amino functional organic group and a mercapto functional organic group is disclosed. A method of making such amino-mercapto functional organopolysiloxanes is by reacting (A) a silanol-functional polysiloxane, (B) an amino functional alkoxy silane, and (C) a mercapto functional alkoxy silane, via a condensation reaction. The amino-mercapto functional organopolysiloxanes products are useful in textile and fabric treatments. |
| US08399590B2 |
Superhydrophilic amphiphilic copolymers and processes for making the same
A superhydrophilic amphiphilic copolymer and process for making the superhydrophilic amphiphilic copolymer includes a low molecular weight polysaccharide modified with a hydrophobic reagent, such as substituted succinic anhydride. The superhydrophilic amphiphilic copolymer system generates stable foam for use in applications, such as healthcare formulations, with low irritation of the eyes and skin. |
| US08399588B1 |
Methods of constructing alkene-based copolymer polyolefins having reduced crystallinity
The invention is a novel family of polyolefins characterized by chain-walking defects of the type that add extra backbone carbons per monomer. These polyolefins display a large decrease in crystallinity relative to polyolefins known in the art. Specifically, the reduction in crystallinity is much greater than for earlier polypropylenes with a matched content of stereo or 1-alkene type defects. The claimed polyolefins can be an alkene-based copolymer. The defects in the polyolefin backbone are generated by a chain walking mechanism in which three or more carbons per monomer are added to the polymer backbone instead of two, as in conventional polymerization or copolymerization methods of alpha olefins. The novel polyolefins can be used in applications such as plastic wrapping, thin films, co-extrusion layers or molded parts in the absence of polymer blending or copolymerization. The cost of materials production can be reduced. |
| US08399585B2 |
Process for producing water-absorbing polymer particles with improved blood absorbance by polymerizing droplets of a monomer solution
A process for producing water-absorbing polymer particles with improved blood absorbence by polymerizing droplets of a monomer solution in a surrounding gas phase, wherein the monomer solution comprises a surfactant. |
| US08399584B2 |
Copolymers having zwitterionic moieties and dihydroxyphenyl moieties and medical devices coated with the copolymers
Copolymers are manufactured to include a zwitterionic monomer (e.g., methacryloyloxyethyl phosphorylcholine monomer), a dihydroxyphenyl derivatized monomer, and optionally one or more additional monomers. The dihydroxyphenyl derivatized monomer gives the copolymers excellent adhesion properties. Optional monomers include a cationic amino monomer, a hydrocarbon monomer, and/or a hydrophilic monomer. The copolymers are biocompatible and can be used with medical devices. |
| US08399583B2 |
Polymer, curable resin composition, cured product, and article
A polymer which has a radical polymerizable unsaturated group in a side chain and can be made a molecular design suitable for the purpose; a curable resin composition containing the polymer, which provides a cured product having high surface hardness after curing and hardly suffering from scratch; the cured product; and an article obtained by laminating the cured product are provided. The polymer (A) of the present invention is obtained by polymerizing, at least, a vinyl monomer represented by the following general formula (1) and a cyclic ether compound represented by the following general formula (2). The polymer (A) of the present invention is preferably obtained by polymerization of 1 wt % or more and 99.9 wt % or less of a vinyl monomer represented by the general formula (1), 0.1 wt % or more and 99 wt % or less of a cyclic ether compound represented by the general formula (2) and 0 wt % or more and 98.9 wt % or less of the other cationic polymerizable monomer. [wherein R1 represents an alkylene group having 2 to 8 carbon atoms, R2 represents a hydrogen atom or a methyl group, and m represents a positive integer] [wherein n represents an integer of 1 to 5]. |
| US08399582B2 |
Polymerisation of ethylene and alpha-olefins with pyridino-iminophenol complexes
The present invention relates to the field of single site catalyst systems based on pyridine-iminophenol, pyridine-iminoalcohol or pyridine-iminoamine complexes and suitable for oligomerising or homo- or co-polymerising ethylene and alpha-olefins. |
| US08399581B2 |
Polyethylene films with improved physical properties
Metallocene catalyzed polyethylenes are found to have improved physical properties, improved processability and improved balance of properties. Surprisingly, there is a direct relationship between MD shrinkage, and MD tear. Additionally, MD tear is greater than TD tear, and MD tear is also greater than intrinsic tear. MD tear to TD tear ratios are above 0.9, and dart drop impact is above 500 g/mil. The polyethylenes have a relatively broad composition distribution and relatively broad molecular weight distribution. |
| US08399579B2 |
Process for preparing an aqueous composite-particle dispersion
A process for preparing stable aqueous dispersions of composite particles. |
| US08399577B2 |
Curable epoxy resin composition
A curable epoxy resin composition including at least an epoxy resin component and a hardener component, and optionally further additives, wherein: (a) the epoxy resin component is an epoxy resin compound or a mixture of such compounds; (b) the hardener component includes (b1) an aliphatic and cycloaliphatic or aromatic polycarbonic acid anhydride; and (b2) a polyether-amine of the general formula (I), H2N—(CnH2n—O)m—CnH2n—NH2, wherein n is an integer from 2 to 8; and m is from about 3 to about 100; (c) the polycarbonic acid anhydride [component (b1)] is present in the curable epoxy resin composition in a concentration of 0.60 Mol to 0.93 Mol; and (d) the polyether-amine of the general formula (I) [component (b2)] is present in the curable epoxy resin composition in a concentration of about 0.02 Mol to about 0.1 Mol. |
| US08399576B2 |
Phosphorus containing novalac phenol resins, methods for manufacturing the same, and formulae containing the same
Disclosed is a phosphorous containing phenol novolac resin, having a structure as below: In the above formula, Z is selected from — or —CH2—. Each Y is independently selected from —, —CH2—, —C(CH3)2—, —S—, —SO2—, —O—, —CO—, or —N═N—. Each X is independently selected from a hydrogen or phosphorous containing group, wherein the hydrogen and phosphorous containing group have a molar ratio of 1:0.1 to 0.1:1. Each R1 is independently selected from a hydrogen or C1-5 alkyl group. Each R2 is independently selected from a C1-5 alkyl group. m is an integer of 1 to 10, and n is 0 or 1. |
| US08399574B2 |
Resin powder composition for slush molding and molded articles
The present invention provides a resin powder composition for slush molding which can give slush molded articles with more excellent hydrolysis resistance. The present invention relates to a resin powder composition for slush molding which is characterized by comprising as the main component a thermoplastic polyurethane resin powder, preferably a thermoplastic polyurethane elastomer powder, and containing a polycarbodiimide prepared by polymerizing tetramethylxylylene diisocyanate, alkoxy terminated one having a number average molecular weight of 500 to 30,000. |
| US08399571B2 |
Silane-modified polyolefins having a high degree of functionalization
The present invention relates to modified polyolefins having a propylene content of at least 50 ma-% and a maximum of 75 ma-%, being determined by means of 13C-NMR spectroscopy, and having a poly(ethylene) triad content of a maximum of 2.5 ma-%, being determined by means of 13C-NMR spectroscopy, relative to the total detected ethylene content, a melting heat of at least 9 and a maximum of 20 J/g, determined by means of differential calorimetry, and a solubility in xylol at ambient temperature of at least 96 ma-%, and a solubility in THF at ambient temperature of at least 67 ma-%, wherein one or multiple silanes are grafted onto the polymer. The invention further relates to a method for the production of the polyolefins, and to the use thereof, particularly in or as an adhesive. |
| US08399570B2 |
Functionalized polymers and improved tires therefrom
A tire component comprising a vulcanized residue of a functionalized polymer defined by the formula I where π is a rubbery polymer chain, B is a boron atom, R1 is a bond or a divalent organic group, and each υ is independently selected from thioalkoxy groups (—SR), amino groups (—NR2), or phosphino groups (—PR2), where each R is independently selected from monovalent organic groups or two R groups form a divalent organic group, which forms a cyclic structure. |
| US08399568B2 |
Resin composition and molded article using the same
This invention provides a resin composition comprising a polyolefin-based polymer and an aliphatic polyester-based polymer, which has an excellent balance of impact resistance and rigidity and excellent properties, such as processability. The resin composition comprises a polyolefin-based polymer (A), an aliphatic polyester-based polymer (B), an elastomer (C), which has a melt flow rate (MFR), measured at 190° C. under a load of 21N, of 0.5 to 3.0 g/10 minutes, and an epoxy group-containing polyolefin-based polymer (D). |
| US08399567B2 |
Optical film and liquid crystal display device comprising the same
The present invention relates to an optical film comprising: a blended resin including 1) an acrylic copolymer resin containing an alkyl methacrylate monomer and a (metha) acrylic monomer containing an alicyclic or an aromatic ring, 2) a copolymer resin containing an alkyl methacrylate monomer, an aromatic vinyl monomer, and an acid anhydride monomer, and 3) a resin containing an aromatic or an alicyclic ring in the main chain of a polymer. The present invention also relates to a method for manufacturing the optical film, and a liquid crystal display device comprising the optical film. The optical film according to the present invention is excellent in heat resistance, optical transparency, mechanical strength, durability, and the like. |
| US08399566B2 |
Modified ionomer composition
The present invention relates to golf balls and golf ball components comprising a blend of one or more ionomers mixed with one or more metal or ammonium salts of chelating agent. The resulting modified ionomer compositions have improved processability as shown by the increase in melt flow index (I2) as compared to the unmodified ionomer analogs while demonstrating an increase in resiliency or speed as shown by increasing COR, while maintaining or showing only a slight increase in hardness as measured by Shore D. |
| US08399563B2 |
Golf ball
An object of the invention is to provide a golf ball excellent in the durability at the normal and low temperatures, flight distance, and shot feeling on the shots. Another object of the present invention is to provide a golf ball excellent in a direction stability on the shots. The present invention provides a golf ball comprising: a core consisting of at least one layer; and a cover covering the core and having a thickness ranging from 0.3 mm to 1.0 mm, wherein the cover is formed from a cover composition that contains as a resin component, (A) a highly elastic polyamide resin (B) a metal-neutralized product of binary copolymer and/or ternary copolymer, and (C) a resin having a polar functional group in a specific amount, and wherein the cover composition has a slab hardness ranging from 65 to 75 in Shore D hardness. |
| US08399558B2 |
Inorganic-organic hybrid composition and use thereof
The present disclosure provides an inorganic-organic hybrid film which is excellent in transparency, adhesion, heat resistance, weatherability, and anti-rust property, whose refractive index may be controlled easily, and which is also excellent in hardness. Also provided are an inorganic-organic hybrid composition as a starting material for the film, and a hard coating material, an optical material, an anti-rust coating material, and a conductive coating material, all utilizing the composition. The composition is characterized by containing organic component (A) composed of monomer component (a1) containing a particular diol (meth)acrylate compound (U) having a urethane bond, or polymer component (a2) containing polymer (P) obtained by polymerization of monomer component (a1), and inorganic component (B), wherein the ratio of the organic component (A) to the inorganic component (B) is 1:99 to 99:1 by mass. |
| US08399545B2 |
Azo pigment-containing aqueous ink for inkjet recording
An aqueous ink for inkjet recording is provided. The aqueous ink ensures that the ejection accuracy in inkjet recording is excellent and helps suppress generation of density unevenness and streak unevenness, even after storage for a long period of time or exposure to high temperatures. The aqueous ink for inkjet recording contains vinyl polymer particles containing components A and B and a water-soluble solvent. Component A is an azo pigment having a specific structure, its tautomer, or a salt or hydrate thereof; and Component B is a vinyl polymer containing (a) a hydrophobic structural unit having an aromatic ring bonded to the polymer main chain through a linking group and (b) a hydrophilic structural unit. |
| US08399540B2 |
Ink-jet ink composition, ink set, and image forming method
An ink-jet ink composition comprising: a pigment, a polymer pigment dispersion, polymer particles, a hydrophilic organic solvent, water, and at least one of a water-soluble acidic compound having a molecular weight of 200 or less or a salt thereof in an amount of from 50 ppm to 1,000 ppm; an ink set that includes the ink-jet ink composition and a treatment liquid that forms an aggregate when contacted with the ink-jet ink composition; and an image forming method using the ink set. |
| US08399534B2 |
EC coating and inks having improved resistance
Energy curable inks formulations are disclosed having improved resistance properties. |
| US08399533B2 |
Photocurable compositions containing N-oxyazinium salt photoinitiators
A photocurable composition includes at least one N-oxyazinium salt photoinitiator, a photosensitizer for the N-oxyazinium salt photoinitiator, an N-oxyazinium salt efficiency amplifier, and one or more photocurable acrylates. This composition can be cured using irradiation under high efficiency. Curing can be carried out in oxygen-containing environment. |
| US08399529B2 |
Method of homogenization and, optionally, analysis for processing moist noble metal-containing recycling materials with an unknown noble metal content
For processing of noble metal-containing, moist recycling materials with an unknown noble metal content (hereinafter called “batch”), a moisture-binding agent is added for homogenisation and the batch is mixed with comminution of optionally pre-sent agglomerates to form a free-flowing and homogenous powder. Optionally, the following takes place subsequently for analysis: A at least one representative, volume-reduced sample is taken first of all, B the sample is dried, C the sample is optionally divided further and D the sample is analyzed and the noble metal content of the batch is calculated on the basis of the data a previously known or pre-calculated quantity of the moisture-binding agent being added before sampling (step A). |
| US08399528B2 |
Method for improved removal of cations by means of chelating resins
The present invention relates to a method for improved removal of cations, preferably alkaline earth metals, in particular calcium and barium, from aqueous solutions using chelating resins having acetic acid and/or iminodiacetic acid groups having high dynamic absorption capacity for cations at a low residual content of the cations and high regeneration efficiency, to the chelating exchangers themselves, and also to uses thereof. |
| US08399525B2 |
Treatment of gaucher disease with specific pharmacological chaperones and monitoring treatment using surrogate markers
Provided is a method of monitoring the treatment of Gaucher disease with specific pharmacological chaperones using systemic and/or cellular surrogate markers. Also provided is a new biomarker that may be used to monitor the progress of such treatment. |
| US08399523B2 |
Quarternization of the additive amino alkylmethacrylate copolymer E for improving permeability and solubility of pharmaceuticals
The present invention relates to a strategy for improving the permeability and solubility of pharmaceuticals, based on adding a chemically modified amino alkyl methacrylate copolymer E, wherein the chemical modification is the quaternization of a fraction of the existing amino alkyl groups. |
| US08399522B2 |
3.2.1-bicyclo-octane compounds
The present invention pertains to a method of counteracting a malodor by introducing a malodor counteracting effective amount of a novel 3.2.1-bicyclo-octane compound represented by formula: wherein R is selected from the group consisting of carbonyl and [1,3]dioxolane; R′ is selected from the group consisting of hydrogen and allyl; or R and R′ taken together represent |
| US08399518B2 |
Administration of 3,5-diiodothyropropionic acid for stimulating weight loss, and/or lowering triglyceride levels, and/or treatment of metabolic syndrome
Methods and compositions are disclosed for stimulating weight loss and/or lowering triglyceride levels in an individual mammal in need thereof. In an exemplary method, a pharmaceutical composition comprising a therapeutically effective amount of DITPA, and optionally one or more lipid-reducing agents, is administered to an individual mammal to stimulate weight loss, and/or reduce levels of triglyceride and/or lipoprotein in the mammal. |
| US08399514B2 |
Treatment for multiple sclerosis
Provided are certain methods of screening, identifying, and evaluating neuroprotective compounds useful for treatment of neurological diseases, such as, e.g., multiple sclerosis (MS). The compounds described upregulate the cellular cytoprotective pathway regulated by Nrf2. Also provided are certain methods of utilizing such compounds in therapy for neurological disease, particularly, for slowing or reducing demyelination, axonal loss, or neuronal and oligodendrocyte death. |
| US08399513B2 |
Levodopa prodrug mesylate hydrate
Crystalline (2R)-2-phenylcarbonyloxypropyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate mesylate, hydrate, methods of making the hydrate, pharmaceutical compositions containing the hydrate, and methods of using the hydrate to treat diseases or disorders such as Parkinson's disease are provided. |
| US08399511B2 |
Two types of crystalline of pinocembrin, their preparation and their use for manufacture of pharmaceutical compositions
Two crystalline forms of pinocembrin of formula (I): α and β, their preparation and their use for manufacture of pharmaceutical compositions. There exists difference between them in bioavailability. They are used for treating and preventing cerebral ischemic diseases by protective action of neurovascular unit, and enhancing blood drug level in vivo. |
| US08399507B2 |
Antidiabetic tricyclic compounds
Tricyclic compounds containing a cyclopropanecarboxylic acid fused to a bicyclic ring, including pharmaceutically acceptable salts, are agonists of G-protein coupled receptor 40 (GPR40) and are useful as therapeutic compounds, particularly in the treatment of Type 2 diabetes, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia. |
| US08399499B2 |
3- to 7-membered 1,3-diaza-4-OXO-heterocyclic derivatives capable of releasing active aldehydes or ketones
The present invention provides 3- to 7-membered 1,3-diaza-4-oxo-heterocyclic derivatives, such as imidazolidinone O derivatives, capable of releasing in a controlled manner a biologically active aldehyde or ketone in the surrounding. The invention also relates to the use of these compounds as perfuming or flavoring ingredients, as well as to the perfuming compositions and consumer articles containing such derivatives. It also provides a process for preparing said derivatives of the invention. |
| US08399497B2 |
Thiazole derivatives and use thereof
The present invention is related to thiazole derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries. |
| US08399496B2 |
Inhalable aztreonam lysinate formulation for treatment and prevention of pulmonary bacterial infections
A method and a composition for treatment of pulmonary bacterial infections caused by gram-negative bacteria suitable for treatment of infection caused by Escherichia coli, Klebsiella pneumoniae, Klebsiella oxytoca, Pseudomonas aeruginosa, Haemophilus influenzae, Proteus mirabilis, Enterobacter species, Serratia marcescens as well as those caused by Burkholderia cepacia, Stenotrophomonas maltophilia, Alcaligenes xylosoxidans, and multidrug resistant Pseudomonas aeruginosa, using a concentrated formulation of aztreonam lysinate delivered as an aerosol or dry powder formulation. |
| US08399490B2 |
Insecticides
An insecticidal compound of formula (I) in which G1, G2, and G3 together with the two carbon atoms to which G1 and G3 are attached, form a non-aromatic 4- or 5-membered ring system; wherein G1 is sulfur, SO, SO2, oxygen, a direct bond, NRa or CR5aR5b; G2 is sulfur, SO, SO2, oxygen, a direct bond, NRb or CR5cR5d; G3 is sulfur, SO, SO2, oxygen, a direct bond, NRc or CR5eR5f; with the provisos that a) not more than 1 group G can be a direct bond, b) not more than 2 G groups can be oxygen, sulfur, SO or SO2 and c) when 2 G groups are oxygen, SO, SO2 and/or sulfur the two groups are separated by a carbon atom; each of Z1 and Z2, which may be the same or different, represents oxygen or sulfur; D is phenyl or a 5- or 6-membered heteroaromatic ring and R1a, R1b, R5a, R5b, R5c, R5d, R5e, R5f, Ra, Rb Rc, R2, R3 and R20 are specified organic groups and agronomically acceptable salts/isomers/enantiomers/tautomers/N-oxides of those compounds. |
| US08399487B2 |
Pyrazole compounds and uses thereof
The invention provides a compound of formula I: wherein R1-R6, X, Y, and B have any of the values described herein, as well as salts of such compounds, compositions comprising such compounds, and therapeutic methods that comprise the administration of such compounds. The compounds are inhibitors of MAO-B enzyme function and are useful for improving cognitive function and for treating psychiatric disorders in animals. |
| US08399478B2 |
Thiophene-carboxamides useful as inhibitors of protein kinases
The present invention relates to compounds useful as inhibitors of protein kinase represented by formula (I): or a pharmaceutically acceptable salt thereof. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions. |
| US08399474B2 |
Method of restoring the incretin effect
The present invention relates to methods of treating metabolic syndrome, Type 2 diabetes mellitus, atherogenic dyslipidemia and/or obesity. The present invention also relates to methods of restoring the incretin effect, to restoring physiologic control of glucagon levels, to restoring first-phase insulin secretion, and to restoring the physiologic glucose-dependent insulin secretion. The methods of the present invention comprise administration of a selective κ-receptor antagonist, such as guanidinylated naltrindole (GNTI), or pharmaceutically acceptable derivatives thereof to a subject in need thereof. |
| US08399470B2 |
Inhibitors of bruton's tyrosine kinase
Disclosed herein are pyrazolo[3,4-d]pyrimidines that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. Methods for the preparation of the compounds are disclosed. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions. |
| US08399469B2 |
Low hygroscopic aripiprazole drug substance and processes for the preparation thereof
The present invention provides low hygroscopic forms of aripiprazole and processes for the preparation thereof which will not convert to a hydrate or lose their original solubility even when a medicinal preparation containing the anhydrous aripiprazole crystals is stored for an extended period. |
| US08399468B2 |
Octahydro-pyrrolo[3,4-B]pyrrole derivatives
Octahydro-pyrrolo[3,4-b]pyrrole derivatives are useful in treating conditions or disorders prevented by or ameliorated by histamine-3 receptor ligands. Octahydro-pyrrolo[3,4-b]pyrrole compounds, methods for using such compounds, compositions for making them, and processes for preparing such compounds are disclosed herein. |
| US08399461B2 |
Bicyclic heterocycles, medicaments containing said compounds, use thereof, and method for production of same
The present invention relates to bicyclic heterocycles of general formula the tautomers, the stereoisomers, the mixtures and the salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids which have valuable pharmacological properties, particularly an inhibitory effect on signal transduction mediated by tyrosine kinases, the use thereof for treating diseases, particularly tumoral diseases, as well as benign prostatic hyperplasia (BPH), diseases of the lungs and respiratory tract, and the preparation thereof. |
| US08399460B2 |
Chromenone derivatives
The invention concerns chromenone derivatives of Formula I or a pharmaceutically-acceptable salts thereof, wherein each of R1, R2, R3, R4, R5, R6, R7, R8, n and R9 has any of the meanings defined hereinbefore in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the treatment of cell proliferative disorders. |
| US08399456B2 |
2,5-disubstituted arylsulfonamide CCR3 antagonists
Provided herein are 2,5-disubstituted arylsulfonamides that are useful for modulating CCR3 activity, and pharmaceutical compositions thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a CCR3-mediated disorder, disease, or condition. |
| US08399454B2 |
Azetidinyl diamides as monoacylglycerol lipase inhibitors
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, Z, R1, and s are defined herein. |
| US08399443B2 |
Treatment of hypertension by renal vascular delivery of guanethidine
Sympathetic nerves run through the adventitia surrounding renal arteries and are critical in the modulation of systemic hypertension. Hyperactivity of these nerves can cause renal hypertension, a disease prevalent in 30-40% of the adult population. Hypertension can be treated with neuromodulating agents (such as angiotensin converting enzyme inhibitors, angiotensin II inhibitors, or aldosterone receptor blockers), but requires adherence to strict regimens and often does not reach target blood pressure threshold to reduce risk of major cardiovascular events. A minimally invasive solution is presented here to reduce the activity of the sympathetic nerves surrounding the renal artery by locally delivering neurotoxic or sympathetic nerve-blocking agents into the adventitia. Extended elution of these agents may also be accomplished in order to tailor the therapy to the patient. |
| US08399437B2 |
Methods for treating spinal muscular atrophy using tetracycline compounds
Methods for using tetracycline compounds for the treatment of spinal muscular atrophy are described. |
| US08399436B2 |
N-pyrazolyl carboxamides as CRAC channel inhibitors
The present invention relates to amide compounds, processes for their preparation, pharmaceutical compositions containing these compounds and to their use in the treatment of disorders, conditions or disorders such as allergic disorders, inflammatory disorders and disorders of the immune system. |
| US08399431B2 |
Cyclodextrin-based polymers for therapeutics delivery
The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical compositions thereof. These cyclodextrin-containing polymers improve drug stability and solubility, and reduce toxicity of the small molecule therapeutic when used in vivo. Furthermore, by selecting from a variety of linker groups and targeting ligands the polymers present methods for controlled delivery of the therapeutic agents. The invention also relates to methods of treating subjects with the therapeutic compositions described herein. The invention further relates to methods for conducting pharmaceutical business comprising manufacturing, licensing, or distributing kits containing or relating to the polymeric compounds described herein. |
| US08399430B2 |
Alkylated semi synthetic glycosaminoglycosan ethers, and methods for making and using thereof
Described herein is the synthesis of alkylated and semi-synthetic glycosaminoglycosan ethers, referred to herein as “SAGEs.” The synthesis of sulfated alkylated SAGEs is also described. The compounds described herein are useful in a number of applications including wound healing, drug delivery, and the treatment of a number of inflammatory diseases and skin disorders. |
| US08399428B2 |
Nucleosides with antiviral and anticancer activity
The invention provides a compound of formula (I), wherein R1-R6 and X have any of the values described, as well as pharmaceutical compositions comprising such compounds and therapeutic methods comprising the administration of such compounds. |
| US08399427B2 |
Reagents, methods and systems to suppress pro-inflammatory cytokines
The present invention relates to reagents, methods and systems to treat inflammation and pain in a subject using small interfering RNA (siRNA) molecules targeted to either TNFα, IL1, IL6 and other pro-inflammatory cytokines. |
| US08399425B2 |
Alleviating neuropathic pain with EETs and sEH inhibitors
The invention discloses methods of using cis-epoxyeicosantrienoic acids (“EETs”), inhibitors of soluble epoxide hydrolase (“sEH”), or a combination of an EET and an inhibitor of sEH, to alleviate neuropathic pain in subjects suffering from such pain. |
| US08399424B2 |
Method for controlling the amount of gene product, and agent for controlling the amount of gene product
The invention relates to a method of intracellularly controlling amounts of gene products, which can increase an amount of gene product intracellularly, comprising a step of introducing into the cell a substance having a sequence complementary to the base sequence of mRNA corresponding to the gene product, its precursor or another substance which can have equivalent action in the cell. |
| US08399423B2 |
Immune regulatory oligonucleotide (IRO) compounds to modulate toll-like receptor based immune response
The invention provides the use of immune regulatory oligonucleotides (IRO) as antagonist of TLRs in the prevention and treatment of a disease caused by a pathogen, for example, a DNA or RNA virus. |
| US08399421B2 |
Treatment for neuropathic pain due to spinal cord injury
The present invention is drawn to treatment of neuropathic pain due to spinal cord injury. In this regard, the present invention discloses methods and composition to treat neuropathic pain. |
| US08399420B2 |
Azacytidine analogues and uses thereof
The present invention is directed toward compounds of Formula (I) as follows: wherein, R is H, R5C(O), R5CH2OC(O), or R5CH2NHC(O); R1 is where the crossing dashed line illustrates the bond formed joining R1 to the molecule of Formula (I); R2 and R3 are independently OH or H, provided that R2 and R3 are not simultaneously OH; R4 is H, R5C(O), R5CH2OC(O), or R5CH2NHC(O), provided that R and R4 are not simultaneously H; and R5 has the general formula: CH3—(CH2)n—(CH═CH—CH2)m—CH═CH—(CH2)k—; k is an integer from 0 to 7; m is an integer from 0 to 2; and n is an integer from 0 to 10, or a pharmaceutical salt thereof. Methods of making and using these compounds are also disclosed. |
| US08399419B2 |
Antibacterial aminoglycoside analogs
Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Z1, Z2, Z3, Z4, R1, R2 and R3 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed. |
| US08399414B2 |
Analgesics
The object of this invention is to provide a novel pharmaceutical composition for getting rid of pains and anxiety in patients. This invention relates to a pharmaceutical composition containing lactoferrin as an active ingredient. The composition of this invention is useful for treatment of at least one disease or condition selected from the group consisting of pains, including the phase 1 pain and the phase 2 pain, anxiety and stress. The composition is particularly beneficial to alleviating or getting rid of the pain and anxiety which significantly lower quality of life of patients with end-stage cancer. The composition of this invention is also useful for treatment of pains, including the phase 1 pain and the phase 2 pain, and inflammation which accompany arthritis or diseases in the junctions of bones (e.g. rheumatoid arthritis, osteoarthritis, frozen shoulder, sports injuries such as tennis elbow and baseball shoulder, and low back pain). |
| US08399413B2 |
Low frequency glatiramer acetate therapy
A method of alleviating a symptom of relapsing-remitting multiple sclerosis in a human patient suffering from relapsing-remitting multiple sclerosis or a patient who has experienced a first clinical episode and is determined to be at high risk of developing clinically definite multiple sclerosis comprising administering to the human patient three subcutaneous injections of a therapeutically effective dose of glatiramer acetate over a period of seven days with at least one day between every subcutaneous injection so as to thereby alleviate the symptom of the patient. |
| US08399411B2 |
Composition for animal consumption and method for reducing MAP kinase activity
This invention is directed generally to compositions (including foods nutritional supplements, treats, and toys) for animal consumption, particularly compositions that comprise omega-3 and omega-6 polyunsaturated fatty acids, and particularly compositions that tend to aid in reducing mitogen-activated-protein (“MAP”) kinase activity in animals. This invention also is directed generally to methods for using such compositions, particularly to methods for using such compositions to reduce MAP kinase activity in animals, and particularly to methods for using such compositions to treat a cancer or tissue hyperplasia. This invention is further directed generally to processes for making such compositions. |
| US08399410B2 |
Methods and devices for desmopressin drug delivery
Disclosed are devices for urine voiding postponement, and methods for treating conditions such as central diabetes insipidus, enuresis, nocturia, urinary frequency or incontinence. The devices deliver a desmopressin flux through the skin of a patient in a low dose amount just necessary to achieve a desired anti-diuretic effect without undesirable side effects such as hyponatremia. The devices are designed to permit a state of normal urinary production to return quickly after the desmopressin flux is terminated. |
| US08399403B2 |
Chemical linkers and conjugates thereof
The present disclosure provides drug-ligand conjugates that are potent cytotoxins, wherein the drug is linked to the ligand through either a peptidyl, hydrazine, or disulfide linker. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them. |
| US08399401B2 |
Fusion proteins
A single chain, polypeptide fusion protein, comprising: a non-cytotoxic protease, or a fragment thereof, which protease or protease fragment is capable of cleaving a protein of the exocytic fusion apparatus of a nociceptive sensory afferent; a Targeting Moiety that is capable of binding to a Binding Site on the nociceptive sensory afferent, which Binding Site is capable of undergoing endocytosis to be incorporated into an endosome within the nociceptive sensory afferent; a protease cleavage site at which site the fusion protein is cleavable by a protease, wherein the protease cleavage site is located between the non-cytotoxic protease or fragment thereof and the Targeting Moiety; a translocation domain that is capable of translocating the protease or protease fragment from within an endosome, across the endosomal membrane and into the cytosol of the nociceptive sensory afferent. Nucleic acids encoding the fusion proteins, methods of preparing same and uses thereof are also described. |
| US08399399B2 |
3- and 4-methyl dodecenal and their use in fragrance and flavour compositions
3- and 4-Methyl-4-dodecenal, a method of their production and fragrance and flavor compositions comprising at least one of them. |
| US08399398B2 |
Organoleptic compounds and their use in perfume compositions
The present invention a method of improving, enhancing or modifying a fragrance formulation through the addition of an olfactory acceptable amount of the following compound: wherein R1 and R2 independently represent a straight, branched or cyclic hydrocarbon moiety consisting of less than 10, preferably less than 4, most preferably 1 of 2 carbon atoms. |
| US08399396B2 |
Tiron-containing detergents having acceptable color
Detergent compositions containing catechols, such as Tiron (1,2-dihydroxybenzene-3,5-disulfonic acid), which do not have or do not develop the reddish color associated with the catechol/ferric iron chelate are disclosed. Methods for reducing the intensity of red color in a Tiron (1,2-dihydroxybenzene-3,5-disulfonic acid) containing detergent composition are also disclosed. |
| US08399392B2 |
Method of reducing asphaltene precipitation in an engine utilizing a C22 hydrocarbyl salicylate
A method of reducing asphaltene precipitation or ‘black paint’ in an engine is disclosed. The method includes the step of lubricating the engine with a lubricating oil composition comprising: an oil of lubricating viscosity in a major amount; and, a salicylate detergent system in a minor amount comprising one or more neutral or overbased alkaline earth metal C22 hydrocarbyl substituted salicylates. |
| US08399391B2 |
Photoresist residue removal composition
A photoresist residue removal composition is provided. The photoresist residue removal composition essentially contains glycolic and water, to which a pH control agent and/or a cleanability improver is selectively added. The photoresist residue removal composition has a high capability to remove residues caused by plasma etching and ashing of a metal or silicon oxide layer under a photoresist pattern, does not cause corrosion, and is eco-friendly. |
| US08399389B2 |
Food-grade lubricant compositions comprising estolide compounds
Provided herein are compositions comprising at least one estolide compound of formula: in which n is an integer equal to or greater than 0; m is an integer equal to or greater than 1; R1, independently for each occurrence, is selected from optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched; R2 is selected from hydrogen and optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched; and R3 and R4, independently for each occurrence, are selected from optionally substituted alkyl that is saturated or unsaturated, and branched or unbranched. Also provided are uses of the compositions described herein. |
| US08399386B2 |
Foamers for downhole injection
The present invention relates to a method for introducing a foaming composition including an imidazoline-based compound to a fluid. The foaming composition comprises at least one quaternized compound having an imidazoline moiety. An example of the quaternized compound is a quaternized imidazoline. |
| US08399385B2 |
Plant chimeric binding polypeptides for universal molecular recognition
Libraries of nucleic acids encoding chimeric binding polypeptides based on plant scaffold polypeptide sequences. Also described are methods for generating the libraries. |
| US08399382B2 |
Cotton growth regulator
Protoporphyrinogen oxidase enzyme-inhibiting compounds are useful in compositions and methods for regulating growth of cotton plants. Of particular interest is the use of carfentrazone ethyl and certain metabolites thereof for regulating growth of cotton plants. |
| US08399380B2 |
Herbicidal composition
A herbicidal composition for controlling weeds in orchard lands or non-crop lands which comprises (a) N-(7-fluoro-3,4-dihydro-3-oxo-4-prop-2-ynyl-2H-1,4-benzeoxazin-6-yl) cyclohex-1-ene-1,2-dicarboxamide and (b) 1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-ylsulfonyl)urea as active ingredients, and a mixing ratio (the weight ratio of the active ingredient (a) to the active ingredient (b) of which is from 1:0.1 to 10. |
| US08399373B2 |
Zeolitic catalysts, their process for preparation and their applications
The invention describes a porous composite material that comprises a porous substrate based on a refractory inorganic oxide in which said substrate has a zeolite crystal content that is less than 25% by mass, whereby said crystals are dispersed homogeneously in the pores of said substrate, and the distribution coefficient that is measured by Castaing microprobe is between 0.75 and 1.25, and in which the total pore volume of said substrate represents at least 40% of the initial total pore volume of the substrate, and the mean diameter of the pores represents at least 50% of the mean diameter of the pores of the initial substrate, its process for preparation and its use as catalyst in the hydrocarbon feedstock conversion reactions. |
| US08399371B2 |
Optical glass
An optical glass in includes SiO2, B2O3, Al2O3, BaO, CaO, ZnO, La2O3, Gd2O3, and Y2O3, each in a specific ratio. Further, the optical glass satisfies the following conditional expressions (1) and (2), taking the content of SiO2 as A, the content of B2O3 as B, the content in total of La2O3, Gd2O3 and Y2O3 as C, and the content in total of SiO2 and B2O3 as D. 0.35 |
| US08399370B2 |
Glass composition
A glass composition which is reduced in the amount of residual bubbles and is produced using smaller amounts of an environmentally unfriendly component such as arsenic oxide and antimony oxide. This glass composition comprises, in terms of mass %; 40-70% SiO2; 5-20% B2O3; 10-25% Al2O3; 0-10% MgO; 0-20% CaO; 0-20% SrO; 0-10% BaO; 0.001-0.5% Li2O; 0.01-0.5% Na2O; 0.002-0.5% K2O; and 0-1.0%, excluding 0%, Cl. |
| US08399369B2 |
Optical glass and optical element
An object of the present invention is to provide optical glass having improved glass-devitrification resistance and moldability without causing reduction in refractive index, and also provide an optical element using the optical glass as a raw material. Specifically, the present invention provides an optical glass containing components of, by mol %: B2O3: over 60% through 75%; Bi2O3: 24% to 39%; La2O3: 7% or lower; Gd2O3: 7% or lower; and ZrO2: 7% or lower. |
| US08399362B2 |
Apparatus for forming a film and an electroluminescence device
A device having three evaporation sources and a unit for moving the respective evaporation sources in one chamber is used, whereby it becomes possible to increase efficiency of use of an evaporation material. Consequently, manufacturing cost can be reduced, and a uniform thickness can be obtained over an entire surface of a substrate even in the case in which a large area substrate is used. |
| US08399359B2 |
Manufacturing method for dual damascene structure
A manufacturing method for a dual damascene structure includes providing a substrate having a dielectric layer, a first hard mask layer and a second hard mask layer sequentially formed thereon, performing a first double patterning process to sequentially form a plurality of first trench openings and a plurality of second trench openings in the second hard mask layer, performing a second double patterning process to sequentially form a plurality of first via openings and a plurality of second via openings in the fist hard mask layer, and transferring the first trench openings, the second trench openings, the first via openings, and the second via openings to the dielectric layer to form a plurality of dual damascene openings. |
| US08399357B2 |
Method of manufacturing semiconductor device
A method of manufacturing a semiconductor device is disclosed. The method forms a semiconductor device including a workpiece structure having a first region and second region located adjacent to the first region formed therein. The first region includes a first pattern and the second region includes a second pattern having at least a greater pattern width or a smaller aspect ratio than the first pattern. The method includes forming the first pattern by providing a first film having a first contact angle at a top portion thereof and the second pattern by providing a second film having a second contact angle less than the first contact angle at a top portion thereof; cleaning the first and the second regions by a chemical liquid; rinsing the cleaned first and the second regions by a rinse liquid; and drying the rinsed first and the second regions. |
| US08399356B2 |
Manufacturing method of semiconductor device
A conductive film containing aluminum or an aluminum alloy with a thickness equal to or greater than 1 μm and equal to or less than 10 μm is etched by wet-etching to be a predetermined thickness, and then etched by dry-etching, whereby side-etching of the conductive film can be suppressed and thickness reduction of a mask can be suppressed. The suppression of side-etching of the conductive film and the suppression of thickness reduction of the mask enable a conductive film containing aluminum or an aluminum alloy even with a large thickness equal to or greater than 1 μm and equal to or less than 10 μm to be etched such that the gradient of the edge portion of the conductive film can be steep, a predetermined thickness of the conductive film can be obtained, and shape difference from a mask pattern can be suppressed. |
| US08399355B2 |
Stacked semiconductor package and method for manufacturing the same
A stacked semiconductor package includes a semiconductor chip module including at least two semiconductor chips, each semiconductor chip having a first face, a second face opposite to the first face, and a circuit part. A through portion passes through the first and second faces of the semiconductor chip. A recess part is formed in a portion of the second face where the second face and the through portion meet. A through electrode is electrically connected to the circuit part and is disposed inside of the through portion. A connection member is disposed in the recess part to electrically connect the through electrodes of adjacent stacked semiconductor chips. And the semiconductor chip module is mounted to a substrate. The stacked semiconductor package prevents both gaps between semiconductor chips and misalignment of the through electrode. |
| US08399352B2 |
Semiconductor device comprising self-aligned contact bars and metal lines with increased via landing regions
When forming metal lines of the metal zero level, a reduced bottom width and an increased top width may be achieved by using appropriate patterning regimes, for instance using a spacer structure after forming an upper trench portion with a top width, or forming the lower portion of the trenches and subsequently applying a further mask and etch regime in which the top width is implemented. In this manner, metal lines connecting to self-aligned contact bars may be provided so as to exhibit a bottom width of 20 nm and less, while the top width may allow reliable contact to any vias of the metallization system. |
| US08399348B2 |
Semiconductor device for improving electrical and mechanical connectivity of conductive pillers and method therefor
A semiconductor device has a semiconductor die having a first surface and a second surface wherein at least one bond pad is formed on the first surface. A passivation layer is formed on the first surface of the semiconductor device, wherein a central area of the at least one bond is exposed. A seed layer is formed on exposed portions of the bond pad and the passivation layer. A conductive pillar is formed on the seed layer. The conductive pillar has a base portion wherein the base portion has a diameter smaller than the seed layer and a stress relief portion extending from a lateral surface of a lower section of the base portion toward distal ends of the seed layer. A solder layer is formed on the conductive pillar. |
| US08399347B2 |
Integrated circuits and methods of forming conductive lines and conductive pads therefor
Integrated circuits and methods for forming conductive lines and conductive pads of integrated circuits are disclosed. One such integrated circuit includes circuitry, a first conductor coupled to the circuitry, a conductive pad coupled to the first conductor, and a second conductor spaced apart from the first conductor and coupled to the conductive pad. The second conductor would be floating but for its coupling to the conductive pad. |
| US08399343B2 |
Method for the selective doping of silicon and silicon substrate treated therewith
A method for the selective doping of silicon of a silicon substrate (1) for producing a pn-junction in the silicon is characterized by the following steps: a) Providing the surface of the silicon substrate (1) with a doping agent (2) based on phosphorous, b) heating the silicon substrate (1) for creating a phosphorous silicate glass (2) on the surface of the silicon, wherein phosphorous diffuses into the silicon as a first doping (3), c) applying a mask (4) on the phosphorous silicate glass (2), covering the regions (5) that are later highly doped, d) removing the phosphorous silicate glass (2) in the non-masked regions, e) removing the mask (4) from the phosphorous silicate glass (2), f) again heating for the further diffusion of phosphorous from the phosphorous silicate glass (2) into the silicon as a second doping for creating the highly doped regions (5), g); complete removal of the phosphorous silicate glass (2) from the silicon. |
| US08399338B2 |
Electronic component manufacturing method
The objective is to limit pickup defects when chips with a semi-cured adhesive layer are picked up following dicing by lowering the adhesive strength of an ultraviolet curable adhesive beforehand while improving the cohesive force. Provided is a dicing method for semiconductor wafers with a semi-cured adhesive layer that comprises a process to coat the back surface of semiconductor wafers with a paste-like adhesive and semi-cure the paste-like adhesive in a sheet form using heating or ultraviolet irradiation to form a semi-cured adhesive layer, a gluing process to glue an adhesive sheet, wherein an ultraviolet curable adhesive is laminated on a base film, onto the semi-cured adhesive layer, an ultraviolet irradiation process to apply ultraviolet irradiation to the ultraviolet curable adhesive, and a dicing process to dice the semi-cured adhesive layer glued to the adhesive sheet and the semiconductor wafers. |
| US08399334B2 |
Method of manufacturing nano device by arbitrarily printing nanowire devices thereon and intermediate building block useful for the method
A method of manufacturing a nano device by directly printing a plurality of NW devices in a desired shape on a predesigned gate substrate. The method includes preparing an NW solution, preparing a building block for performing decaling onto the substrate by carrying an NW device, forming the NW device by connecting electrodes of each of building block units of the building block using NWs by dropping the NW solution between the electrodes and then through dielectrophoresis, visually inspecting the numbers of NW bridges that are formed between the electrodes of each of the building block units through the dielectrophoresis, grouping the building block units according to the numbers, and decaling the NW device formed on each of the building block units onto the gate substrate by bringing the grouped building block units into contact with the predesigned gate substrate and then detaching the grouped building block units. |
| US08399331B2 |
Laser processing for high-efficiency thin crystalline silicon solar cell fabrication
Laser processing schemes are disclosed for producing various types of hetero-junction and homo-junction solar cells. The methods include base and emitter contact opening, selective doping, and metal ablation. Also, laser processing schemes are disclosed that are suitable for selective amorphous silicon ablation and selective doping for hetero-junction solar cells. These laser processing techniques may be applied to semiconductor substrates, including crystalline silicon substrates, and further including crystalline silicon substrates which are manufactured either through wire saw wafering methods or via epitaxial deposition processes, that are either planar or textured/three-dimensional. These techniques are highly suited to thin crystalline semiconductor, including thin crystalline silicon films. |
| US08399329B2 |
Method for manufacturing SOI substrate and semiconductor device
It is an object of the present invention to provide a method for manufacturing an SOI substrate having an SOI layer that can be used in practical applications with high yield even when a flexible substrate such as a glass substrate or a plastic substrate is used. Further, it is another object of the present invention to provide a method for manufacturing a thin semiconductor device using such an SOI substrate with high yield. When a single-crystal semiconductor substrate is bonded to a flexible substrate having an insulating surface and the single-crystal semiconductor substrate is separated to manufacture an SOI substrate, one or both of bonding surfaces are activated, and then the flexible substrate having an insulating surface and the single-crystal semiconductor substrate are attached to each other. |
| US08399327B2 |
Methods of manufacturing a semiconductor device
A method includes forming a plurality of dummy gate structures on a substrate, each dummy gate structure including a dummy gate electrode and a dummy gate mask, forming a first insulation layer on the substrate and the dummy gate structures to fill a first space between the dummy gate structures, planarizing upper portions of the first insulation layer and the dummy gate structures, removing the remaining first insulation layer to expose a portion of the substrate, forming an etch stop layer on the remaining dummy gate structures and the exposed portion of the substrate, forming a second insulation layer on the etch stop layer to fill a second space between the dummy gate structures, planarizing upper portions of the second insulation layer and the etch stop layer to expose the dummy gate electrodes, removing the exposed dummy gate electrodes to form trenches, and forming metal gate electrodes in the trenches. |
| US08399317B2 |
Transistor having an etch stop layer including a metal compound that is selectively formed over a metal gate, and method therefor
In one aspect, an apparatus may include a metal gate of a transistor. An etch stop layer may be selectively formed over the metal gate. The etch stop layer may include a metal compound. An insulating layer may be over the etch stop layer. A conductive structure may be included through the insulating layer to the metal gate. Methods of making such transistors are also disclosed. |
| US08399314B2 |
p-FET with a strained nanowire channel and embedded SiGe source and drain stressors
Techniques for embedding silicon germanium (e-SiGe) source and drain stressors in nanoscale channel-based field effect transistors (FETs) are provided. In one aspect, a method of fabricating a FET includes the following steps. A doped substrate having a dielectric thereon is provided. At least one silicon (Si) nanowire is placed on the dielectric. One or more portions of the nanowire are masked off leaving other portions of the nanowire exposed. Epitaxial germanium (Ge) is grown on the exposed portions of the nanowire. The epitaxial Ge is interdiffused with Si in the nanowire to form SiGe regions embedded in the nanowire that introduce compressive strain in the nanowire. The doped substrate serves as a gate of the FET, the masked off portions of the nanowire serve as channels of the FET and the embedded SiGe regions serve as source and drain regions of the FET. |
| US08399312B2 |
Methods of forming radiation-hardened semiconductor structures
A radiation-hardened semiconductor structure including an insulator material doped with at least one of a transition metal, a lanthanide, and an actinide, and a semiconductor material located over the insulator material. A semiconductor device including the radiation-hardened semiconductor structure is also disclosed, as are methods of forming the radiation-hardened semiconductor structure and the semiconductor device. |
| US08399311B2 |
Thin film transistor array panel and method of manufacture
A thin film transistor array panel includes a gate line formed on a substrate, an interlayer insulating film formed on the gate line and having an opening, a gate insulator formed in the opening, a data line formed on the interlayer insulating film and including a first conductive layer made of a transparent conductive oxide and a second conductive layer made of a metal, a source electrode connected to the data line and made of a transparent conductive oxide, a drain electrode facing the source electrode and made of a transparent conductive oxide, a pixel electrode connected to the drain electrode, and an organic semiconductor contacting the source electrode and the drain electrode. |
| US08399309B2 |
Semiconductor device manufacturing method
A manufacturing method is disclosed which ensures strength of a wafer and improves device performance. A thermal diffusion layer is formed from a front surface of a wafer. A tapered groove which reaches the thermal diffusion layer is formed from a back surface by anisotropic etching with alkaline solution. In-groove thermal diffusion layer is formed on side wall surfaces of the groove. A separation layer of a reverse blocking IGBT is configured of the thermal diffusion layer and the in-groove diffusion layer. The thermal diffusion layer is formed shallowly by forming the in-groove diffusion layer. It is possible to considerably reduce thermal diffusion time. By carrying out an ion implantation forming the in-groove diffusion layer and an ion implantation forming a collector layer separately, it is possible to select an optimum value for tradeoff between turn-on voltage and switching loss, while ensuring reverse blocking voltage of the reverse blocking IGBT. |
| US08399306B2 |
Integrated circuit packaging system with transparent encapsulation and method of manufacture thereof
A method of manufacture of an integrated circuit packaging system includes: forming a substrate having a redistribution line thereon; mounting an integrated circuit to the substrate; and molding a transparent encapsulation over the substrate covering the integrated circuit and the redistribution line and the integrated circuit seen through the transparent encapsulation. |
| US08399301B2 |
Mounting structures for integrated circuit modules
A structure of an integrated circuit module includes a wiring board, a plurality of integrated circuits and at least one terminating resistance circuit. The wiring board has a mounting region on at least one surface thereof. The plurality of integrated circuits are mounted in the mounting region of the wiring board and spaced from one another in a first direction. The at least one terminating resistance circuit is arranged between at least two adjacent integrated circuits, and coupled to an output of a last of the plurality of integrated circuits. |
| US08399299B2 |
Cavity structure comprising an adhesion interface composed of getter material
A method for making a structure including at least the steps of: making at least one first portion of at least one getter material against a first substrate or a second substrate, making at least one second portion of at least one getter material against the second substrate when the first portion of getter material is placed against the first substrate, or against the first substrate when the first portion of getter material is placed against the second substrate, and attaching the second substrate to the first substrate by thermocompression of a first part of the first portion of getter material against at least one part of the second portion of getter material, forming at least one cavity delimited by the first substrate and the second substrate, a second part of the first portion of getter material being placed in the cavity. |
| US08399296B2 |
Airgap micro-spring interconnect with bonded underfill seal
A method of assembling a package includes aligning a pad chip with a spring chip to form at least one interconnect in an interconnect area, adhering the pad chip to the spring chip so that there is a gap between the pad chip and the spring chip, dispensing underfill material into the gap to seal the interconnect area from an environment external to the package, and curing the underfill material to form a solid mold. |
| US08399294B2 |
Semiconductor package for discharging heat and method for fabricating the same
A semiconductor package for quickly discharging heat and a method for fabricating the same are disclosed. The semiconductor package includes a semiconductor package module having a first insulation member and at least one fluid passage passing through the insulation member. Circuit patterns are formed on a first face of the first insulation member. Semiconductor chips are then disposed on the first face and are electrically connected with the circuit patterns respectively. A second insulation member is formed so as to surround the side faces of the semiconductor chips, the first insulation member, and the circuit patterns. Finally, a through electrode is formed passing through the second insulation member of the semiconductor package module and electrically connecting to the circuit patterns. |
| US08399290B2 |
Organic transistor with fluropolymer banked crystallization well
A method is provided for fabricating a printed organic thin film transistor (OTFT) with a patterned organic semiconductor using a fluropolymer banked crystallization well. In the case of a bottom gate OTFT, a substrate is provided and a gate electrode is formed overlying the substrate. A gate dielectric is formed overlying the gate electrode, and source (S) and drain (D) electrodes are formed overlying the gate dielectric. A gate dielectric OTFT channel interface region is formed between the S/D electrodes. A well with fluropolymer containment and crystallization banks is then formed, to define an organic semiconductor print area. The well is filled with an organic semiconductor, covering the S/D electrodes and the gate dielectric OTFT channel interface. Then, the organic semiconductor is crystallized. Predominant crystal grain nucleation originates from regions overlying the S/D electrodes. As a result, an organic semiconductor channel is formed, interposed between the S/D electrodes. |
| US08399289B2 |
Programmable polyelectrolyte electrical switches
An apparatus includes a first solid electrode on a substrate, a polyelectrolyte layer over a part of the first solid electrode, a second solid electrode on a portion of the polyelectrolyte layer, and an anchoring layer on the part of the first solid electrode. The polyelectrolyte layer is either chemically bonded to the anchoring layer or has a thickness of less than about 20 nanometers. |
| US08399286B2 |
Semiconductor device and method of making thereof
A method of making a semiconductor device includes providing a web substrate, forming a first semiconductor layer of a first conductivity type over the web substrate, forming a second semiconductor layer of a second conductivity type over a first side of the first semiconductor layer, forming a first electrode layer over the second semiconductor layer, forming a handle web substrate over the first electrode layer, delaminating the web substrate from the first semiconductor layer after the step of forming the handle web substrate, where at least one opening extends through the first and the second semiconductor layers, and forming a second electrode layer over a second side of the first semiconductor layer such that the first and second electrode layers are in electrical contact with each other. |
| US08399284B2 |
Method of manufacturing the organic light-emitting display
A thin film deposition apparatus, which has high external light transmittance and a cathode having a uniform thickness, is disclosed. In one embodiment, the thin film deposition apparatus includes a deposition source spaced apart from a center of the substrate and configured to emit a deposition material toward the substrate and a blocking member disposed on the substrate and configured to block at least part of the deposition material emitted from the deposition source, wherein an opening is defined on at least one side of the blocking member. |
| US08399283B2 |
Bifacial cell with extruded gridline metallization
Provided is a bifacial photovoltaic arrangement comprising a bifacial cell which included a semiconductor layer having a first surface and a second surface, a first passivation layer formed on the first surface of the semiconductor layer and a second passivation layer formed on the second surface of the semiconductor layer, and a plurality of metallizations formed on the first and second passivation layers and selectively connected to the semiconductor layer. At least some of the metallizations on the bifacial photovoltaic arrangement comprising an elongated metal structure having a relatively small width and a relatively large height extending upward from the first and second passivation layers. |
| US08399282B2 |
Method for forming pad in wafer with three-dimensional stacking structure
A method for forming a pad in a wafer with a three-dimensional stacking structure is disclosed. The method includes bonding a device wafer that includes an Si substrate and a handling wafer, thinning a back side of the Si substrate, depositing an anti-reflective layer on the thinned back side of the Si substrate, depositing a back side dielectric layer on the anti-reflective layer, forming vias that pass through the anti-reflective layer and the back side dielectric layer and contact back sides of super contacts which are formed on the Si substrate, and forming a pad on the back side dielectric layer such that the pad is electrically connected to the vias. |
| US08399280B2 |
Method for protecting an integrated circuit chip against laser attacks
A method for protecting, against laser attacks, an integrated circuit chip formed inside and on top of a semiconductor substrate and including in the upper portion of the substrate an active portion in which are formed components, this method including the steps of: forming in the substrate a gettering area extending under the active portion, the upper limit of the area being at a depth ranging between 5 and 50 μm from the upper surface of the substrate; and introducing diffusing metal impurities into the substrate. |
| US08399277B2 |
Compound semiconductor light-emitting diode and method for fabrication thereof
A compound semiconductor light-emitting diode includes a light-emitting layer (133) formed of aluminum-gallium-indium phosphide, a light-emitting part (13) having component layers individually formed of a Group III-V compound semiconductor, a transparent supporting layer (14) bonded to one of the outermost surface layers (135) of the light-emitting part (13) and transparent to the light emitted from the light-emitting layer (133), and a bonding layer (141) formed between the supporting layer (14) and the one of the outermost surface layers (135) of the light-emitting part (13) containing oxygen atoms at a concentration of 1×1020 cm−3 or less. |
| US08399272B2 |
Method of manufacturing semiconductor light emitting element
A method of manufacturing the semiconductor light emitting element comprises a semiconductor layer forming step of forming the multilayered nitride semiconductor layer on the first wafer having a transparent property; a bonding step of bonding the multilayered nitride semiconductor layer to the first wafer; a groove forming step of forming the groove extending from the lower surface of the first wafer to the multilayered nitride semiconductor layer; a light applying step of applying a first light to the lower surface of the multilayered nitride semiconductor layer through the first wafer to reduce a bonding force between the multilayered nitride semiconductor layer and the first wafer; a separating step of separating the first wafer from the multilayered nitride semiconductor layer; and a cutting step of cutting the second wafer along the groove to divide into a plurality of the semiconductor light emitting element. |
| US08399265B2 |
Device for releasably receiving a semiconductor chip
A device is disclosed for releasably receiving a singulated semiconductor chip having a first main surface and a second main surface opposite the first main surface. The device includes a support structure. At least one elastic element is arranged on the support structure. Electrical contact elements are arranged on the at least one elastic element and adapted to be contacted to the first main surface of the semiconductor chip. A foil is adapted to be arranged over the second main surface of the semiconductor chip. |
| US08399264B2 |
Alignment inspection
The present disclosure relates to the field of microelectronic substrate fabrication and, more particularly, to alignment inspection for vias formed in the microelectronic substrates. The alignment inspection may be achieved by determining the relative positions of fluorescing and non-fluorescing elements in a microelectronic substrate. |
| US08399259B2 |
Measuring device, measuring apparatus and method of measuring
The measuring device of the invention includes: a first container and a second container for holding a sample; and an optical measurement part for carrying out an optical measurement. The first container has a first sample supply inlet for supplying a sample containing an analyte to the first container and at least one electrode. The second container has a second sample supply inlet for supplying the sample to the second container and a reagent holding part for holding a reagent for the optical measurement. |
| US08399258B2 |
Biological markers for longevity and diseases and uses thereof
This invention provides methods of using of the sizes and levels of high-density lipoprotein (HDL) and low-density lipoprotein (LDL) particles, the −641 allele of the promoter of the gene encoding apolipoprotein C-3 (APOC-3), the 405 allele of the gene encoding cholesteryl ester transfer protein (CETP), and plasma levels of insulin-like growth factor-1 (IGF-1), adiponectin, CETP and APOC-3, for determining and increasing an individual's likelihood of longevity and of retaining cognitive function during aging, and for determining and decreasing an individual's likelihood of developing a cardiovascular-, metabolic- or age-related disease. |
| US08399257B2 |
Transposition of maize Ac/Ds elements in vertebrates
The present invention is directed to the use of the maize Ac/Ds transposable elements in vertebrates. |
| US08399253B2 |
Proliferation culture methods using micro-scaffolds for regulations of cell-to-cell signals
A three-dimensional cell culture method for increasing cell proliferation efficiency by suitably regulating the proliferation-inducing and proliferation-inhibitory signals between cells is provided. The method includes repeatedly performing any one or both of the following processes a) and b) so as to regulate proliferation-inducing and proliferation-inhibitory signals between the cells: a) a process of gradually adding the micro-scaffolds, in which a small amount of the micro-scaffolds are used in an initial stage in order to maintain a suitable distance between the cells, and the amount of the micro-scaffolds is then increased slowly according to cell proliferation rate; and b) a periodic shaking process, in which shaking is performed in order to separate connected cells from each other by a physical force, after the cells are incubated for more than a given period of time. |
| US08399251B2 |
Use of the extracellular marker DNER for identification and selection of specific pancreatic cells
The invention relates to a method of identifying and obtaining cells that have the potential to differentiate into pancreatic cells, having the step of contacting a cell population containing endocrine pre-progenitor cells, endocrine progenitor cells, early endocrine cells, and/or fully differentiated endocrine cells with a DNER binding agent; as well as isolating and/or expanding cells obtained by the method and compositions thereof. |
| US08399250B1 |
Anti-mpl ligand (thromobpoietin) antibodies
Isolated mpl ligand, isolated DNA encoding mpl ligand, and recombinant methods of preparing mpl ligand are disclosed. These mpl ligands are shown to influence the replication, differentiation or maturation of blood cells, especially megakaryocyte progenitor cells. Accordingly, these compounds are used for treatment of thrombocytopenia. |
| US08399249B2 |
Procedure for the generation of a high producer cell line for the expression of a recombinant anti-CD34 antibody
The present invention relates to cell capture assay for the selection of a high producer cell line expressing anti-CD34 antibodies that recognize the CD34 membrane-protein in the cell membrane. The monoclonal antibody secreted by the hybridoma cell line 9C5/9069 binds to human CD34 and is used to isolate stem cells. The DNA sequences encoding for the antibody heavy and light chain have been identified, isolated from the hybridoma cells and cloned into appropriate expression vectors. After co-transfection of the heavy and light chain genes into HEK293T or in CHO cells either conditioned medium or purified antibody were assessed for binding to CD34 protein located in the cell membrane in different cell capture assays. The binding of the antibody to CD34-positive cells could be shown with these assays for several cell lines. |
| US08399247B2 |
Methods and apparatus for selectively processing eggs having identified characteristics
Methods and apparatus for processing eggs based upon a characteristic such as gender are provided. Material is extracted from each of a plurality of live eggs, the extracted material is assayed to identify eggs having the characteristic, and then eggs identified as having the characteristic are processed accordingly. |
| US08399246B2 |
Baculovirus expression vector and method therewith for generating immunogenicity in a host
A baculovirus expression vector achieves dual functions of (1) subunit vaccine by displaying the influenza surface protein for humoral immune responses; and (2) DNA vaccine by expressing influenza surface protein for long-acting cellular immune response. A method for inducing immunogenicity in a host is also disclosed. |
| US08399245B2 |
Rotation system for cell growth chamber of a cell expansion system and method of use therefor
A system and method for rotating a cell growth chamber of a cell expansion system includes a rotatable member for engaging a chamber coupling attached to the cell growth chamber. The rotatable member includes an independently operable mechanism for engaging a rotatable fitting associated with the chamber coupling. In at least one embodiment, the chamber coupling is selectively rotatable by turning the rotatable member, thereby rotating the cell growth chamber around a first axis. The cell growth chamber is also selectively rotatable around a second axis by turning the rotatable fitting associated with the chamber coupling. Other novel aspects include a way of attaching the cell growth chamber to the shaft assembly, and a new tube routing clip. |
| US08399241B2 |
Modulators of alpha-synuclein toxicity
Disclosed are compositions and methods for modulating expression of genes that function at the step of ER of Golgi trafficking. Compounds that modulate expression of these genes of activity of the encoded proteins can be used to inhibit alpha-synuclein mediated toxicity and used to threat of prevent synucleinopathies such as Parkinson's disease. Also disclosed are methods of identifying inhibitors of alpha-synuclein mediated toxicity. |
| US08399237B2 |
Pseudomonas alcaliphila MBR and its application in bioreduction and biosorption
The present invention relates to microbiology technology field. More particularly, it relates to Pseudomonas alcaliphila MBR CGMCC 2318 which has the ability to reduce and adsorb metal and nonmetal ions. It also relates to methods of bioreduction and biosorption using the said strain by means of its property of reducing nitrate to ammonium and adsorbing metal ions to reduce the metal and nonmetal ions in the solution to elementary state under aerobic conditions. The present invention also relates to application of the said strain in bio-metallurgy, production of metal and nonmetal elementary substance, treatment of wastewater containing metal ions, and removal of harmful metal and nonmetal ions contained in soil and water. The strain of the present invention is easy to cultivate. The method of bioreduction and biosorption by it is very simple and can be widely used in metallurgy, treatment of wastewater and removal of harmful substances in soil and water. |
| US08399236B2 |
System comprising bacteriophages and particles that contain active substances
The present invention concerns a system, comprising bacteriophages and particles comprising active agents, in which a first additional peptide is fused to proteins of the bacteriophage, the first additional peptide adheres to the surface of the particle and furthermore a second additional peptide is fused to proteins of the bacteriophage. The second additional peptide can adhere on substrate surfaces. The present invention furthermore concerns the use of the system for delayed release of active agents and also a method for production of the system. The present invention furthermore concerns a method for the selection of phage species from a combinatorial phage population. |
| US08399234B2 |
Perhydrolase variant providing improved specific activity
An acetyl xylan esterase variant having perhydrolytic activity is provided for producing peroxycarboxylic acids from carboxylic acid esters and a source of peroxygen. More specifically, a Thermotoga maritima acetyl xylan esterase gene was modified using error-prone PCR and site-directed mutagenesis to create an enzyme catalyst characterized by an increase in specific activity. The variant acetyl xylan esterase may be used to produce peroxycarboxylic acids suitable for use in a variety of applications such as cleaning, disinfecting, sanitizing, bleaching, wood pulp processing, and paper pulp processing applications. |
| US08399231B2 |
Thermus thermophilus nucleic acid polymerases
The invention provides novel nucleic acid polymerases from strains GK24 and RQ-1 of Thermus thermophilus, and nucleic acids encoding those polymerases, as well as methods for using the polymerases and nucleic acids. |
| US08399224B2 |
Production of ethanol from barley and DDGS containing reduced beta-glucan and phytic acid
Described herein is a method of preparing DDGS containing reduced levels of beta-glucan and phytic acid suitable for an animal feed. |
| US08399223B2 |
Composition containing arazyme for the prevention and treatment of cancer
The invention provides a method for treating lung cancer or breast cancer wherein the method comprises administering a pharmaceutically effective dose of arazyme enzyme to a subject with lung cancer or breast cancer. The arazyme enzyme is either a protein comprising the amino acid sequence of SEQ ID NO: 1; and/or a protein encoded by DNA comprising the coding region of the nucleotide sequence of SEQ ID NO: 2. |
| US08399222B2 |
Compositions and methods for detecting small RNAs, and uses thereof
Compositions and methods are provided for the detection of small RNA target nucleic acids, preferably miRNA target nucleic acids, wherein the compositions and methods provide for sensitive and specific detection of the target nucleic acids. The compositions and methods include using one or more of a first amplification oligomer that is preferably an extender primer, a target capture oligomer that is preferably at least partially double stranded, a promoter primer/provider, a reverse primer that is preferably a universal primer and a detection probe. The compositions and methods are useful for diagnostics, prognostics, monitoring the effectiveness of treatment and/or determining a treatment. |
| US08399221B2 |
Methods for detection and quantitation of small RNAs
Improved methods that increase the specificity and sensitivity of detection of small RNAs, including miRNAs, using oligonucleotide primers and nucleic acid amplification, are provided. Reaction conditions that result in preferential decrease in cDNA synthesis of RNAs other than the small RNA molecules targeted for detection during miRNA tailing and reverse transcription reactions are described. Using these reaction conditions greater sensitivity and specificity of amplification of small RNAs including miRNAs is achieved. |
| US08399220B2 |
Antibacterial compositions
The present invention relates to oral antibacterial compositions comprising trihydroxybenzoate derivatives, e.g., useful for the treatment of gum diseases (e.g., gingivitis or periodontitis) and to methods of using such compositions. |
| US08399218B2 |
Engineered zinc finger proteins targeting 5-enolpyruvyl shikimate-3-phosphate synthase genes
The present disclosure relates to engineered zinc finger proteins that target 5-enolpyruvyl shikimate-3-phosphate synthase (EPSPS) genes in plants and methods of using such zinc finger proteins in modulating gene expression, gene inactivation, and targeted gene modification. In particular, the disclosure pertains to zinc finger nucleases for targeted cleavage and alteration of EPSPS genes. |
| US08399215B2 |
Pentose sugar fermenting cell
The invention relates to a cell which comprises a nucleotide sequence encoding a xylose isomerase, wherein the amino acid sequence of the xylose isomerase has at least about 70% sequence identity to the amino acid sequence set out in SEQ ID NO: 3 and wherein the nucleotide sequence is heterologous to the host. The cell of the invention may be used in a process for producing a fermentation product, such as ethanol. Such a process may comprise fermenting a medium containing a source of xylose with a cell of the invention such that the cell ferments xylose to the fermentation product. |
| US08399208B2 |
Method and kit for the measurement of neutrophil cell activation
The present invention is related to accurate detection methods for the measurement only of myeloperoxidase (MPO) levels or neutrophils, preferably equine neutrophils, in complex biological samples. The present invention is further related to ELISA and SIEFED assays for such detection. SIEFED detection sensitivity of active peroxidase activity was found to be enhanced by the addition of nitrite. Such MPO measurement finds its use in many applications such as the prediction, diagnosis and/or monitoring of pathologies correlated with neutrophil activation and/or destruction; the evaluation of drugs and/or immunomodulators; the assessment of immune responses, either natural and/or after treatment with immunomodulators and/or drugs; and the study of cells and their ability to fight microorganisms and/or to destroy them. |
| US08399206B2 |
Methods for diagnosis, prognosis and methods of treatment
The present invention provides an approach for the determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, expression markers and other criteria, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of modulators of cellular activation allows for characterization of pathways and cell populations. Several exemplary diseases that can be analyzed using the invention include AML, MDS, and MPN. |
| US08399201B2 |
Polypeptide complex of TRPM8 and calmodulin and its uses thereof
The present invention discovered that a mammalian TRPM8 binds to calmodulin. The present invention provides a polypeptide complex comprising a cold-menthol receptor (TRPM8) or an active fragment or derivative of TRPM8 and a calmodulin or an active fragment or derivative of calmodulin, and the uses of the polypeptide complex. |
| US08399198B2 |
Assays with droplets transformed into capsules
System, including methods, apparatus, compositions, and kits, for assays with an emulsion including capsules. A method of performing an assay is provided. In the method, an aqueous phase may be provided. The aqueous phase may include a sample and an effective concentration of one or more skin-forming proteins. An emulsion may be formed. The emulsion may include droplets of the aqueous phase disposed in a nonaqueous continuous phase. The emulsion may be heated to create an interfacial skin between each droplet and the continuous phase, to transform the droplets into capsules. Assay data related to the sample may be collected from the capsules. |
| US08399196B2 |
Nucleic acid sequencing methods, kits and reagents
The present invention relates to nucleic acid sequencing methods, kits and reagents, and more particularly to methods of sequencing nucleic acid which employ a nucleic acid processing enzyme and one or more nucleotide analogues that are capable of binding to the active site of the enzyme and to complementary bases in the nucleic acid molecule being sequenced, but which are non-incorporable or inhibitors of the nucleic acid processing enzyme. In further aspects, the present invention relates to conjugates which comprise a deoxyribonucleotide triphosphates (DNTPs) or an analogue thereof linked to an intercalating dye. |
| US08399194B2 |
Heteropolynucleotide duplexes with purine—purine base pairing
The present invention relates to stable anti-parallel heteropolynucleotide duplexes, comprising a plurality of complementary purine-purine nucleobase dyads, wherein the nucleobase is coupled to a pentose sugar backbone. The present invention further relates to methods of hybridizing two heteropolynucleotide molecules to form such purine-purine nucleobase dyads, as well as kits and solid supports comprising such purine-purine nucleobase dyads. |
| US08399193B2 |
DNA methylation biomarkers for lung cancer
The present invention relates to the identification of novel DNA biomarkers and the use of the aberrant methylation patterns of the biomarkers to diagnose a disease or a condition (e.g., a cancer) associated therewith. In particular, the present invention relates to the use of the novel DNA biomarkers to diagnose lung cancers, e.g., squamous cell carcinomas and adenocarcinomas. |
| US08399192B2 |
Using populations of beads for the fabrication of arrays on surfaces
The present invention provides a method of creating an array of features. The method can include steps of (a) providing a plurality of beads, wherein each bead in the plurality of beads includes probe content; (b) contacting the plurality of beads with a surface to produce a layer of beads on the surface; and (c) transferring the probe content from the beads to the surface to create an array of spatially discrete features on the surface, wherein each spatially discrete feature includes probe content from a bead in the plurality of beads. |
| US08399189B2 |
Primers for melting analysis
Methods and kits are provided for nucleic acid analysis. In an illustrative method a target nucleic acid is amplified using a first primer and a second primer, wherein the first primer comprises a probe element specific for a locus of the target nucleic acid and a template-specific primer region, and the probe element is 5′ of the template-specific primer region, subsequently allowing the probe element to hybridize to the locus to form a hairpin, generating a melting curve for the probe element by measuring fluorescence from a dsDNA binding dye as the mixture is heated, wherein the dye is not covalently bound to the first primer, and analyzing the shape of the melting curve. Kits may include one or more of the first and second primers, the dsDNA binding dye, a polymerase, and dNTPs. |
| US08399186B2 |
Simultaneous detection of metabolic enzyme activity and metabolite levels
Provided are methods for detecting a metabolic disorder in an individual using mass spectrometry. One method involves (a) contacting a sample containing (i) a metabolically indicative enzyme and (ii) a metabolic analyte, with a substrate for the enzyme to produce a reaction admixture, under conditions wherein the enzyme is capable of acting on a corresponding substrate to generate a product, and wherein a protease inhibitor is present; (b) contacting the reaction admixture with a reagent that inhibits the ability of the enzyme to act on a corresponding substrate, wherein the metabolic analyte and the product are soluble in the reagent; to produce a test sample and (c) determining the presence or amount of the metabolic analyte and the product contained in the test sample using mass spectrometry, wherein a determined presence or amount of the metabolic analyte and the product correlates with presence or absence of the metabolic disorder. |
| US08399184B2 |
Method for laser interference lithography using diffraction grating
A method for laser interference lithography using a diffraction grating includes (a) forming a photoresist layer on a work substrate to which a repeated fine pattern is to be formed; (b) forming a refractive index matching material layer on the photoresist layer; (c) forming on the refractive index matching material layer a diffraction grating layer having a period of diffraction grating within the range from λ/ng to λ/n0 (λ is a wavelength of laser beam, ng is a refractive index of the diffraction grating, and n0 is a refractive index in the air or in vacuum); and (d) exposing the photoresist layer by means of mutual interference of positive and negative diffracted lights with the same absolute value by inputting a laser beam perpendicularly to the diffraction grating layer. This method allows to realize an interference pattern with higher resolution and to use a laser source with lower coherence. |
| US08399182B2 |
Method of fabricating liquid crystal display device
A method of fabricating a transflective type liquid crystal display device includes: forming gate and data lines with a gate insulating layer therebetween on a substrate and crossing each other to define a pixel region that includes a switching region, a reflective region, and a transmissive region; forming a thin film transistor corresponding to the switching region and connected to the gate and data lines; forming a first passivation layer on the thin film transistor; forming a reflective plate on the first passivation layer in the reflective region; forming a second passivation layer on the reflective plate; forming a pixel electrode on the second passivation layer and connected to a drain electrode of the thin film transistor; forming a third passivation layer on the pixel electrode. |
| US08399179B2 |
High aspect ratio microstructures
A method for forming a high aspect ratio microstructure (20) comprises: a) forming on a conductive surface (4) of a carrier substrate (3) one or more dielectric structures (6) to create a mandrel (7); b) forming masking material (8) by electrodepositing on exposed areas of the conductive surface of the mandrel one or more metal structures; c) forming a composite structure (18) by taking a photopolymer structure comprising a substrate (12) having thereon an electromagnetic radiation-sensitive photopolymer of either a positive tone or a negative tone (14), the photopolymer having a thickness substantially equal to the desired height of the microstructure to be formed, and adhering the photopolymer to the masking material (8), wherein the masking material is opaque to the electromagnetic radiation; d) removing the carrier (3); e) exposing the photopolymer (14) to electromagnetic radiation so as to irradiate regions of the photopolymer corresponding to the one or more dielectric structures (6) and substantially not to irradiate regions of the photopolymer corresponding to the one or more metal structures (8); and f) developing to selectively remove those portions of the photopolymer exposed to the radiation if the photopolymer has a positive tone; or to selectively remove the unexposed portions of the photopolymer if the photopolymer has a negative tone, thereby forming a high aspect ratio microstructure (20). The invention also provides a composite structure (18) for use in the method. |
| US08399177B2 |
Enhanced relief printing plate
An improved relief printing plate and method for producing said plate is disclosed. Substantially all sizes of relief features resolve a fixed pattern which improves print quality. The pattern is applied to image areas in halftone data used to produce an image mask that is subsequently used to convert a plate precursor into a relief plate. The accuracy, ink density and tonal response of printed images corresponding to relief features that include the pattern are comparable or better than relief features produced without the pattern. |
| US08399176B2 |
Photosensitive resin composition
Disclosed is a photosensitive resin composition suitable for use in a transflective liquid crystal display (LCD). The photosensitive resin composition uses, as an alkali-soluble binder resin, a blend of two kinds of binder resins. The first binder resin has a weight average molecular weight greater than or equal to 1,000 but lower than 20,000 and contains no reactive group. The second binder resin has a weight average molecular weight greater than or equal to 20,000 but lower than 80,000 and contains reactive groups. The photosensitive resin composition has good adhesion to an underlying substrate while forming a high resolution fine pattern. |
| US08399173B2 |
Resist composition and resist pattern forming method
The present invention provides a resist composition prepared by dissolving components in an organic solvent containing ethyl lactate, which suppresses deterioration of sensitivity with time and also has required lithographic characteristics, and a method for forming a resist pattern. The resist composition is prepared by dissolving a resin component (A) which exhibits changeable alkali solubility under an action of an acid, an acid generator component (B) which generates an acid upon exposure, an amine (D) and acetic acid in an organic solvent (S) containing ethyl lactate. |
| US08399170B2 |
Process for production of liquid developer, and liquid developer produced by the process
Production process for a liquid developer for use in electrophotograph or electrostatic recording by coacervation method. The process can produce a liquid developer in which a coloring agent (e.g., a pigment) is included completely within a resin particle by distillation of a solvent while retaining the state where the coloring agent is finely dispersed and the resulting colored resin particle is small in particle size with excellent dispersion stability, and excellent optical properties. |
| US08399166B2 |
Toner for developing electrostatic image, full color toner kit, and image formation method
Disclosed are a toner for developing an electrostatic image, a full color toner kit and an image formation method layer, the toner comprising at least a resin and a colorant, wherein the colorant includes quinacridone pigment having a number average primary particle size of from 30 to 150 nm and having a ratio of a long axis length to a short axis length of from 1.0 to 2.0. |
| US08399163B2 |
Method of detecting alignment mark and method of manufacturing printed circuit board
When an alignment mark does not exist within an area of an image obtained by a camera, the coordinate of the alignment mark is calculated based on an identification mark existing in the area of the image and a previously stored positional relationship between the alignment mark and the identification mark. A distance by which a long-sized base material is to be moved for causing the alignment mark to be positioned within the imaging area of the camera is calculated based on the calculated coordinate of the alignment mark, and the long-sized base material is moved by the calculated distance. |
| US08399159B2 |
Mask blank substrate
Provided is a mask blank substrate that can reduce the change in flatness of a main surface thereof before and after chucking to make very small the position offset caused by a photomask and that can significantly reduce the difference in tendency of substrate deformation before and after chucking between photomasks. In a mask blank substrate having two main surfaces and four end faces, a central point is set on the main surface, a first axis of symmetry that passes through the central point and that is parallel to one of the end faces and a second axis of symmetry that passes through the central point and that is perpendicular to the first axis of symmetry are respectively set, measurement points are set in the form of a grid with respect to the first axis of symmetry and the second axis of symmetry so as to measure heights of the main surface from a reference plane at the measurement points, respectively, differences each between measured height values at those measurement points located at positions that are axisymmetric with respect to the first axis of symmetry are calculated, and those differences corresponding to at least 95% of the total number of the calculated differences between the measured height values are within a predetermined value. |
| US08399158B2 |
High resolution phase shift mask
Techniques are disclosed for fabricating lithography masks, which include a first level process comprising lithography and etching to form mask frame and in-die areas, and a second level process comprising lithography and etching to form one or more mask features in the in-die area. At least one of the mask features has a smallest dimension in the nanometer range (e.g., 32 nm technology node, or smaller). The techniques may be embodied, for example, in a lithography mask for fabricating semiconductor circuits. In one such example case, the mask includes a frame area and an in-die area formed after the frame area. The in-die area includes one or more mask features, at least one of which has a smallest dimension of less than 100 nm. The mask has a critical dimension bias of less than 20 nm and a structure that comprises a substrate and an absorber layer. |
| US08399156B2 |
Volume phase hologram recording material and optical information recording medium using the same
Disclosed are a volume phase hologram recording material having high sensitivity, high contrast, and excellent multiple recording and record holding properties and a volume phase hologram recording medium using the same. The volume phase hologram recording material comprises mainly a polymer matrix (a), a radically photopolymerizable compound (b), and a radical photopolymerization initiator (c) and the polymer matrix is a three-dimensionally crosslinked or linear polymer matrix formed from a polymer matrix-forming material containing 0.5-50 wt % of an episulfide compound (f), an epoxy compound (g), and a curing agent (h). |
| US08399153B2 |
Production of membrane electrode assemblies and stacks thereof
In a method for the production of a membrane electrode assembly comprising a membrane, electrodes and a catalyst, the catalyst is pressed into the membrane material, e.g. when forming the material in situ. |
| US08399152B2 |
Method of producing fuel cell catalyst layer
Provided is a method of producing a fuel cell catalyst layer which has a large specific surface area and high activity and which includes the steps of: forming a dendritic structural member including a catalyst precursor by a vapor phase method; providing a coating layer on a surface of the dendritic structural member; and subjecting the dendritic structural member having the coating layer provided thereon to a reduction treatment. The dendritic structural member including a catalyst precursor is a dendritic structural member including platinum oxide or a dendritic structural member containing a composite oxide of platinum oxide and an element except platinum. |
| US08399151B2 |
Fuel cell with buffer-defined flow fields
An oxygen-containing gas flow field is formed on a surface of a cathode side metal separator of a fuel cell. The oxygen-containing gas flow field is connected between an oxygen-containing gas supply passage and an oxygen-containing gas discharge passage. A coolant flow field is formed on the other surface of the cathode side metal separator, on the back of the oxygen-containing gas flow field. The cathode side metal separator has linear guide ridges protruding from an intermediate height area toward the oxygen-containing gas flow field to form a continuous guide flow field, and bosses protruding from the intermediate height area toward the coolant flow field to form an embossed flow field. |
| US08399150B2 |
Integrated fuel cell assembly and method of making
An integrated fuel cell assembly is described. The integrated fuel cell assembly includes a polymer membrane; an anode electrode and a cathode electrode on opposite sides of the polymer membrane; a pair of gas diffusion media on opposite sides of the polymer membrane, the gas diffusion media comprising a microporous layer and a gas diffusion layer, the anode electrode and the cathode electrode positioned between the polymer membrane and the pair of gas diffusion media; a subgasket positioned around a perimeter of one of the gas diffusion media, the subgasket defining an active area inside the perimeter, the subgasket having a layer of thermally activated adhesive thereon; and a bipolar plate sealed to the subgasket by the layer of thermally activated adhesive. Methods of making the integrated fuel cell assembly and assembling fuel cell stacks are also described. |
| US08399147B2 |
Electrolyte-electrode assembly comprising an apatite-type oxide electrolyte and method for manufacturing the same
An electrolyte-electrode assembly (MEA) includes: an electrolyte; an anode side electrode and a cathode side electrode formed so as to sandwich the electrolyte via intermediate layers. The anode side electrode has a thickness set to 1 μm, for example. A method for manufacturing the electrolyte-electrode assembly, i.e., the MEA includes a step for forming the anode side electrode by sputtering. |
| US08399145B2 |
Membrane electrode assembly
A membrane electrode assembly having a peripheral edge region and a central region. The membrane electrode assembly comprises an ion-conducting membrane, first and second electrocatalyst layers disposed either side of the ion-conducting membrane, and first and second gas diffusion layers disposed either side of the first and second electrocatalyst layers respectively. The membrane electrode assembly further comprises an edge protection member, the edge protection member comprising a film layer, a bonding layer, and one or more additives selected from the group consisting of free radical decomposition catalyst, self regenerating antioxidant, hydrogen donors (H-donor) primary antioxidant, free radical scavenger secondary antioxidant, oxygen absorbers (oxygen scavenger) and elemental palladium. The edge protection member is positioned between the membrane and the first and/or second gas diffusion layer at the peripheral edge region of the membrane electrode assembly, and the edge protection member overlaps the first and/or second electrocatalyst layers. |
| US08399142B2 |
Relative humidity profile control strategy for high current density stack operation
A control strategy results in a relative humidity profile that is substantially the same or constant regardless of the operational power level of the fuel cell stack. The strategy maintains the relative humidity profile within a range that enables high current density operation of the fuel cell stack. The profile is achieved by adjusting a coolant flow rate through the fuel cell stack to maintain a temperature change across the coolant flow path from inlet to outlet substantially constant regardless of the operational power level of the fuel cell stack. |
| US08399141B2 |
Fuel cell system and fuel cell power managing method
A fuel cell system and a fuel cell power managing method in which the fuel cell system controls a current output of a fuel cell by adjusting a target voltage value of the fuel cell according to a difference between a current value of the fuel cell and a target constant current value. By doing so, the fuel cell system may allow the fuel cell to stably and constantly output a constant current. |
| US08399138B2 |
Liquid rechargeable lithium ion battery
One embodiment includes a method for recharging a lithium ion battery, including providing a lithium ion battery comprising used liquid electrode material; removing said used liquid electrode material from said lithium ion battery; and, introducing a relatively unused liquid electrode material into the lithium ion battery to replace the used liquid electrode material. |
| US08399137B2 |
Electrolyte for electrochemical device and the electrochemical device thereof
The present invention provides an electrolyte containing novel additive for electrochemical device and the electrochemical device thereof. The additive is a compound represented by below formula (I): wherein R1 and R2 are independently hydrogen, methyl, ethyl, or halogen; n and m are independently 1, 2, or 3. The additive of the present invention can protect the surface of the carbonaceous material on the anode and suppress the occurrence of exfoliation, thereby increasing the lifetime of the electrochemical device. Furthermore, the additive of the present invention also slows down the decay of capacity on the cathode during charging-discharging cycles, and hence maintains a better performance. |
| US08399136B2 |
Electrolyte solution for lithium ion secondary battery, lithium ion secondary battery, fluoroalkane derivative and gelling agent
The electrolyte solution for a lithium ion secondary battery according to the present invention contains a nonaqueous solvent, a lithium salt and a compound represented by the general formula (Z) shown below. Thereby, a lithium ion secondary battery having high battery characteristics and simultaneously achieving a high safety as well can be provided. R—SO2—Ar1—O—R1 (Z) wherein Ar1 denotes a substituted or nonsubstituted divalent aromatic group having 5 to 30 atoms of the nucleus(es); R1 denotes a saturated or unsaturated monovalent hydrocarbon group having 1 to 20 carbon atoms; and R denotes a saturated or unsaturated monovalent hydrocarbon group having a perfluoroalkyl group and having 2 to 22 carbon atoms. |
| US08399132B2 |
Niobium oxide-containing electrode and lithium battery including the same
A niobium oxide-containing electrode includes a collector; and an active material layer formed on the collector, the active material layer including an active material, a conducting agent and a binder; and niobium oxide on the active material layer on the collector. |
| US08399129B2 |
Negative electrode for lithium secondary battery, and lithium secondary battery including the same
A negative electrode for a lithium secondary battery of the present invention includes a current collector and a negative electrode active material layer carried on the current collector. The negative electrode active material layer includes a plurality of columnar particles. The current collector has a surface including a depression and a plurality of projected regions defined by the depression. The projected regions carry the columnar particles. Further, the present invention relates to a lithium secondary battery using the foregoing negative electrode. According to the present invention, it is possible to provide a high-capacity negative electrode excellent mainly in cycle characteristics for a lithium secondary battery, and a lithium secondary battery including the same. |
| US08399126B2 |
Non-aqueous electrolyte and non-aqueous electrolyte secondary battery
A non-aqueous electrolyte is provided that includes a non-aqueous solvent and an electrolyte salt, wherein the non-aqueous solvent contains a fluorinated ether (1) represented by the following Formula: HCF2CF2CF2CH2—O—CF2CF2H (1). This non-aqueous electrolyte has good wettability to a polyolefin separator, can provide a battery with excellent load characteristics for a long period, does not easily decompose in the battery under high-temperature storage, and causes little gas generation due to decomposition. Furthermore, a non-aqueous electrolyte secondary battery is provided that includes a positive electrode, a negative electrode, a separator, and the above-described non-aqueous electrolyte. |
| US08399125B2 |
Cap assembly and secondary battery using the same
A cap assembly and a secondary battery using the cap assembly, the cap assembly including: a cap-up having a groove; a PTC thermistor disposed in the groove; and inner components disposed below the cap-up. The inner components can include a vent disposed under the cap-up; a cap-down disposed under the vent; a sub-plate disposed under the cap-down; and an insulating vent disposed between the vent and the cap-down The secondary battery includes: an electrode assembly; a can containing the electrode assembly, having an opening at one side; and the cap assembly to seal the opening of the can. |
| US08399119B2 |
Battery module and method for cooling the battery module
A battery module and a method for cooling the battery module are provided. The battery module includes a battery cell and a cooling fin disposed adjacent to the battery cell. The cooling fin has a solid plate and first and second tab portions extending from first and second edges, respectively, of the solid plate. The first and second tab portions are bent perpendicular to a front surface of the battery cell. The cooling fin extracts heat energy from the battery cell thereto. The battery module further includes a first cooling manifold that contacts the first tab portion of the cooling fin. The first cooling manifold has at least one flow channel extending therethrough that receives a fluid therethrough. The first cooling manifold conducts heat energy from the cooling fin into the fluid flowing through the first cooling manifold to cool the battery cell. |
| US08399118B2 |
Battery module and method for cooling the battery module
A battery module and a method for cooling the battery module are provided. The battery module includes a first battery cell and a cooling fin disposed adjacent to the first battery cell. The cooling fin has first and second headers, an extruded housing, and a flow diverter. The first and second headers are coupled to first and second ends, respectively, of the extruded housing. The extruded housing has a first plurality of flow channels and a second plurality of flow channels extending therethrough that fluidly communicate with the first and second headers. The flow diverter is disposed in the first header to induce a fluid to flow from the first header through the first plurality of flow channels in the extruded housing to the second header to extract heat energy from the first battery cell. |
| US08399116B2 |
Optimized dimensional relationships for an electrochemical cell having a coiled core
An electrochemical storage cell having a coiled core is disclosed. The coiled core includes a cathode sheet, an anode sheet, and a separator sheet. An anode connector is connected with the anode sheet at a first end of the coiled core and a cathode connector is connected with the cathode sheet at a second, opposite end of the coiled core. The coiled core has a length Lcore and a width Wcore and each connector has a width Wconnector. The length of the coiled core Lcore, width of the coiled core Wcore, and width of each connector Wconnector have the relationship 0<(Wcore−Wconnector)/Lcore<0.37. |
| US08399115B2 |
System and apparatus for monitoring large battery stacks using wireless sensor networks
Monitoring individual cells within large battery stacks used in alternative fuel vehicles is provided using wireless sensor networks. In one embodiment, a battery stack comprised of a plurality of cells includes a plurality of wireless sensor nodes each electrically connected to a corresponding one of the plurality of cells. Each of the wireless sensor nodes includes a sensor circuit for measuring individual performance characteristics for cells to which the wireless sensor nodes are connected. This cell-specific performance data may then be wirelessly transmitted to an external node, which is coupled to a vehicle battery management system configured to determine at least one of a state of charge, state of health and remaining useful life data for the overall battery stack based on the performance characteristics of the battery stack's individual cells. |
| US08399114B2 |
Battery module
A battery module includes a first unit cell, a second unit cell, a first exhaust chamber, and a second exhaust chamber. The first unit cell is disposed so that a positive electrode terminal faces the first direction. The second unit cell is connected in series to the first unit cell, the negative electrode terminal is disposed so as to face the first direction, and the second unit is disposed so as to be adjacent to the first unit cell. The first exhaust chamber is disposed so as to face the positive electrode terminal of the first unit cell, and discharges a gas which is emitted from the positive electrode terminal of the first unit cell. The second exhaust chamber is disposed so as to face the positive electrode terminal of the second unit cell, and discharges a gas generated from the positive electrode terminal of the second unit cell. The end surface of the second unit cell in the first direction and the outer surface of the first exhaust chamber in the first direction are flush with each other. The end surface of the first unit cell in a second direction opposite to the first direction and the outer surface of the second exhaust chamber in the second direction are flush with each other. |
| US08399113B2 |
Nonaqueous electrolyte secondary battery
An object of the present invention is to provide a high-energy density nonaqueous electrolyte secondary battery that controls the rise in temperature during short circuiting.Used is a nonaqueous electrolyte secondary battery 1, including a battery case 2, and a positive electrode plate 5 having a positive electrode current collector and a positive electrode mixture layer containing a cathode material capable of absorbing and desorbing lithium, a negative electrode plate 6 having a negative electrode current collector and a negative electrode mixture layer containing an anode material capable of absorbing and desorbing lithium, a separator 7 held between the positive and negative electrode plates, and a nonaqueous electrolyte that are enclosed in the battery case, wherein at least one of the positive electrode plate 5 and the negative electrode plate 6 has an electrode plate resistance, as determined in the charged state in the thickness direction when pressurized at 50 kg/cm2, of 0.4 Ω·cm2 or more. |
| US08399112B2 |
Battery module and battery pack using the same
A battery module 100 includes a plurality of batteries aligned and accommodated in a housing 20, wherein each batteries has an opening portion 17 at an electrode portion 16 of the battery to release gas generated in the battery outside the battery, the housing 20 is partitioned by a circuit board 30 disposed in contact with battery cases 5 around the electrode portions 16 of the batteries into a storage portion 54 in which the batteries are stored, and an exhaust chamber 24 via which the gas released from the opening portion 17 of the electrode portion 16 is exhausted outside the housing 20, the electrode portions 16 of the batteries are connected to a connector 32 on the circuit board 30, and the opening portions 17 of the electrode portions 16 are in communication with the exhaust chamber 24 via through holes 36 in the circuit board 30. |
| US08399111B2 |
Battery pack
A battery pack includes a bare cell having a pair of first side portions, a pair of second side portions, and a pair of plane portions, each of which are opposite to each other. The second side portions and the plane portions are connected to ends of the first side portions. A protection circuit module is electrically connected to the bare cell. An inner frame exposes one side portion of the pair of first side portions and accommodates the bare cell. An outer frame exposes the pair of plane portions and accommodates the bare cell, the protection circuit module and the inner frame. In the battery pack, outer ribs extending away from the bare cell are further formed at the inner frame that comes in contact with the pair of second side portions of the bare cell so that the outer frame is surrounded by the outer ribs. |
| US08399107B2 |
Composition for making metal matrix composites
In one embodiment, a composition (10) to be mixed with a molten metal to make a metal matrix composite, the composition characterized by: a ceramic reinforcing filler (12), the ceramic reinforcing filler not being wettable by molten aluminum and/or not being chemically stable in molten aluminum, the ceramic reinforcing filler being coated with a ceramic material, the ceramic material being wettable by and chemically stable in molten aluminum. In a related embodiment, a composition (20) to make a porous preform to be infiltrated by molten metal to make a metal matrix composite, the composition characterized by: a ceramic reinforcing filler (23), the ceramic reinforcing filler not being wettable by molten aluminum, the ceramic reinforcing filler being coated with a ceramic material (22) and optionally with a metal (21) such as nickel, the ceramic material being wettable by molten aluminum. The ceramic material can be coated on the ceramic reinforcing filler by a vacuum deposition technique such as vacuum sputtering. |
| US08399105B2 |
Polymer latex suitable for the preparation of dip-molded articles
The present invention relates to a polymer latex made by free-radical emulsion polymerization comprising polymer particles containing structural units derived from at least one conjugated diene component, whereby said polymer particles comprise at least one hard phase segment and at least one soft phase segment, wherein the polymer latex is particularly suitable for the production of dip-molded articles. Furthermore, the present invention relates to a process for making such a polymer latex, to the use of said polymer latex for the production of dip-molded articles, to a compounded polymer latex composition that is suitable for the production of dip-molded articles, to a method for making dip-molded latex articles, as well as to the latex articles obtained thereby. |
| US08399104B2 |
Composite molded article and process for producing the same
The present invention provides a composite molded article and a method for producing the same. The composite molded article comprises a molded article of an olefin thermoplastic elastomer (A) and a molded article of an olefin thermoplastic elastomer (B) fused to each other, wherein the olefin thermoplastic elastomer molded article (A) contains an olefin thermoplastic elastomer composition (A′) having less than 5% by weight of a cyclohexane-soluble(s) and less than 35% of a compression set (JIS K6262, 70° C., 22 hours), and the olefin thermoplastic elastomer molded article (B) contains an olefin thermoplastic elastomer composition (B′) obtained by blending 100 parts by weight of an ethylene/α-olefin/non-conjugated diene copolymer rubber (b-1) containing 6 to 15 wt % of a non-conjugated diene unit, with 40 to 150 parts by weight of a mineral oil softener (b-2), 5 to 150 parts by weight of an olefin resin (b-3), and 0.01 to 20 parts by weight of a crosslinking agent (b-4) and subsequent dynamic heat treatment thereof. |
| US08399100B2 |
Reflection film, reflection film laminate, LED, organic EL display, and organic EL illuminating instrument
The present invention provides a reflection film, a reflection film laminate which are less likely to undergo agglomeration or sulfidation of an Ag thin film due to heat, and a LED, an organic EL display, and an organic EL illuminating instrument, each including any of these. The reflection film in accordance with the present invention is a reflection film formed on a substrate, characterized by being an Ag alloy film including Ag as a main component, and Bi in an amount of 0.02 atomic percent or more, and further including one or more of V, Ge, and Zn in a total content of 0.02 atomic percent or more, and satisfying the following expression (1): 7×[A]+13×[Bi]≦8 (1) where [A] (atomic percent) denotes the content of one or more of the V, Ge, and Zn, and [Bi] (atomic percent) denotes the content of Bi. Whereas, a reflection film laminate in accordance with the present invention is a reflection film laminate formed on a substrate, characterized by including: a first film comprising an Ag alloy film including Ag as a main component, and Bi in an amount of 0.02 atomic percent or more, and further including one or more of V, Ge, and Zn in a total content of 0.02 atomic percent or more, and satisfying the expression (1); and a second film including a Si oxide formed on the first film. |
| US08399098B2 |
Laminates comprising ionomer interlayers with low haze and high moisture resistance
A laminate comprises an ionomeric interlayer sheet which, in turn, comprises or is prepared from a sodium/zinc mixed ionomer that comprises carboxylate groups and a combination of counterions that consists essentially of sodium cations and zinc cations. The sodium/zinc mixed ionomer is the neutralization product of a precursor acid copolymer. The precursor acid copolymer comprises copolymerized units of an α-olefin and an α,β-ethylenically unsaturated carboxylic acid, and it has a melt flow rate of about 70 to about 1000 g/10 min. In addition, the precursor acid copolymer, when neutralized to a level of about 40% to about 90%, and when comprising counterions that consist essentially of sodium ions, produces a sodium ionomer that has a freeze enthalpy that is not detectable or that is less than about 3.0 j/g, when determined by differential scanning calorimetry. |
| US08399096B2 |
High-clarity ionomer compositions and articles comprising the same
An ionomer composition comprises an ionomer that is the neutralized product of a precursor acid copolymer. The precursor acid copolymer comprises copolymerized units of an α-olefin having 2 to 10 carbon atoms and about 20 to about 30 wt %, based on the total weight of the precursor acid copolymer, of copolymerized units of an α,β-ethylenically unsaturated carboxylic acid having 3 to 8 carbon atoms; a melt flow rate of about 10 to about 4000 g/10 min; and, when neutralized to a level of about 40% to about 90% and when comprising counterions that consist essentially of sodium cations, the precursor acid copolymer produces a sodium ionomer that has a melt flow rate of about 0.7 to about 25 g/10 min and a freeze enthalpy that is not detectable or that is less than about 3.0 j/g. Further provided are articles comprising the ionomer composition. |
| US08399093B2 |
Process for preparing redispersible surface-modified silicon dioxide particles
Provided is a process for preparing surface-modified silicon dioxide particles with a mean particle diameter of at most 100 nm, involving (A) high-pressure grinding of a predispersion having (i) surface-modified silicon dioxide particles which are at least partly aggregated, are bonded to the surface-modifying component via Si—O—Si bonds, and still have reactive groups on their surface; (ii) an organosilicon compound which has a silicon-carbon bond and a functional group which can react with the reactive groups to form a covalent Si—O—Si bond; and (iii) a solvent, to form a dispersion; and (B) removing the liquid phase of the dispersion. Also provided are redispersible, surface-modified silicon dioxide particles obtained by this process, and their use in toner powders, silicone rubber, adhesives, and scratch-resistance surface coatings. |
| US08399092B2 |
Zinc oxide particle having high bulk density, method for producing it, exoergic filler, exoergic resin composition, exoergic grease and exoergic coating composition
A zinc oxide particle having large particle diameter and being high-density is provided. An exoergic resin composition, an exoergic grease and an exoergic coating composition containing the zinc oxide particle exhibit an excellent exoergic property. The zinc oxide particle being high-density, has a density of 4.0 g/cm3 or more, median size (D50) of 17 to 10000 μm and tap bulk density of 3.10 g/cm3 or more. |
| US08399087B2 |
Stack of interfolded absorbent sheet products
A stack of interfolded absorbent sheet products comprises a plurality of absorbent sheets each of which is itself folded at least twice about axes that are perpendicular to one another. The absorbent sheets have an embossed surface relief of a predetermined pattern or design. Each of the absorbent sheets within the stack comprises at least one pair of panels sandwiched between a pair of adjacent panels of another of the absorbent sheets in the stack. |
| US08399084B2 |
Resistive implant welding for assemblies of plastic components
A novel method and set of structures for performing resistive implant welding of two plastic components to form an assembly. A first one of the components to be welded includes a channel structure which receives the resistive implant and maintains it in a desired position until the welding operation is performed. The second component to be welded includes a complementary structure including a land which is sized to engage the channel structure and captive resistive implant on the first component. The two components are pre-weld positioned with the land in the channel structure and the positioned components are then placed in a press which exerts a pre-selected pressure on the interface between the channel and the land. Next, a pre-selected electric current is passed through the resistive implant to heat it and to bring the plastic material of the channel structure and the land to their molten points, where they intermingle through the resistive implant. The electrical current is removed and the weld is allowed to cool to its finished state and the welded assembly is removed from the press. |
| US08399083B2 |
Label structure incorporating a leaflet for use on small containers
A label structure is disclosed for mounting on a container and includes a base panel for affixing to a surface of the container. An adhesive is applied to at least a portion of a rear face of the base panel for adhering the base panel to the container. The label structure further includes a leaflet associated with the base panel for application to the container with the base panel, and the leaflet comprising at least one panel with opposite faces. The label structure also includes a laminating strip securing the leaflet to the base panel, and the laminating strip overlies the leaflet and overlying the base panel. In some embodiments, the leaflet is positioned adjacent to the base panel, with a first portion of the leaflet overlying the base panel and a second portion of the leaflet not overlying the base panel. |
| US08399079B2 |
Composition suitable for thermoformable sheets and articles made therefrom
Thermoformable sheet having a thickness of at least 300 micrometers comprising a blend of: (A) from 5 to 20% by weight of a propylene-ethylene copolymer having substantially isotactic propylene sequences, the propylene-ethylene copolymer having a melt flow rate from 4 to 30 g/10 min and comprising at least 70% by weight units derived from propylene and from about 10 to 20% by weight units derived from ethylene; and (B) from 80 to 95% by weight of a polypropylene having a melt flow rate of from 2 to 8 grams/10 minutes, wherein the melt flow rate of the blend is from 2 to 7 grams/10 minutes and wherein the blend exhibits: (1) room temperature Charpy toughness of at least 15 KJ/m2, (2) flexural modulus of at least 1000 MPa, (3) 00 Charpy toughness of at least 2 KJ/m2, and (4) a value for haze of less than 40%. |
| US08399076B2 |
Inkjet recording medium and inkjet recording method
An ink jet recording medium having an ink receiving layer containing a binder which containing an acrylonitrile butadiene type copolymer, the butadiene concentration of the copolymer is 50 weight % or more, and an inorganic pigment on one or two sides of a base paper mainly composed of wood pulp, wherein the concentration ratio of the acrylonitrile butadiene type copolymer to 100 parts by weight of the inorganic pigment is from one part by weight to eight parts by weight, while 60 weight % or more of the inorganic pigment is kaolin with particles of 0.4 μm or more and below 4.2 μm which account for 64% or more as the cumulative value of the volumetric basis when measured using a laser diffraction method, and the surface roughness of the ink receiving layer is from 0.6 μm to 1.4 μm when a hard backing is used at a clamp pressure of 1,000 kPa according to JIS P8151. |
| US08399074B2 |
Compositions for liquid crystal displays
In an exemplary embodiment of the present invention, the content ratio of polar and neutral compounds in a liquid crystal layer is controlled, or a coupling agent that is well adapted to those compounds is used as a material for a sealant, thereby stably maintaining the display quality of the liquid crystal display even at low temperatures. |
| US08399073B2 |
Liquid-crystal medium
The invention relates to a liquid-crystalline medium having negative dielectric anisotropy which comprises at least one compound of the formula I in which R1, R1* and a have the meanings indicated in Claim 1, and to the use thereof for an active-matrix display, in particular based on the VA, PS-VA, PALC, FFS or IPS effect. |
| US08399071B2 |
Process for producing polycrystalline silicon
The process for producing polycrystalline silicon by feeding a reaction gas containing a silane gas and a hydrogen gas into a reaction vessel equipped with silicon core members erected on the electrodes, heating the silicon core members by flowing an electric current thereto to a temperature at which silicon deposits, forming polycrystalline silicon rods by allowing the formed silicon to deposit on the silicon core members, and discharging the discharge gas after the reaction from the reaction vessel, wherein the discharge gas discharged from the reaction vessel is quenched so that the temperature thereof drops from 800° C. down to 500° C. in not longer than 0.1 second. |
| US08399064B2 |
Process for improving the adhesion of carbon fibres with regard to an organic matrix
The invention relates to a process for improving the adhesion of carbon fibers by coating a surface of the carbon fibers with a polymer film containing functional groups capable of acting as chain transfer agents during a chain transfer polymerization of a resin curable by chain transfer polymerization to obtain coated carbon fibers. The coated carbon fibers are then contacted with the curable resin, and the chain transfer polymerization of the curable resin is induced to produce an organic matrix and forming a composite material. The functional groups of the polymer film act as chain transfer agents during the chain transfer polymerization of the curable resin and thereby improve adhesion of the carbon fibers to the organic matrix. Applications of this invention include aeronautical, aerospatial, shipbuilding, railway and motor vehicle industries, armaments industry, sports and leisure articles, and the like. |
| US08399059B2 |
Encapsulated ceramic element and method of making the same
A PZT (lead zirconate titanate) element including one or more outside surfaces including a layer of encapsulation and metallization material and the method of making the same including at least the steps of providing a wafer of ceramic material including a base and one or more walls defining one or more recesses in the wafer which are filled with an encapsulation material. The encapsulation material is then cured and a layer of metallization is applied to one or more of the outside surfaces of the wafer and encapsulation material. Cuts are then made through the layer of metallization and cured encapsulation material to divide the wafer into a plurality of individual and separate ceramic elements with one or more surfaces including a layer of metallization and encapsulation. |
| US08399058B2 |
Masking article and method of masking of substrate
The present disclosure relates to a profiled masking article and method of masking a substrate to be treated or painted that provides a feathered or soft edge between painted and unpainted areas. The masking article described herein may be used as a single strip, or as multiple strips, placed side by side, wherein a strip is removed between treatments of different types. This allows successive treatment layers to completely cover previous layers, thus avoiding defects resulting from exposed layers of material. In an embodiment, the present disclosure is directed to a masking article comprising: at least one elongate body (12), said body (12) having a top surface, a bottom surface and at least two lateral surfaces, wherein at least a portion of said body comprises an adhesive material; and a generally planar top portion (14), connected to the body along at least one surface, said top portion (14) having a microstructured surface. |
| US08399055B2 |
Open channel solid phase extraction systems and methods
The invention provides, inter alia, capillary extraction devices, and methods of making and using the same. |
| US08399053B2 |
Method for dispensing random pattern of adhesive filaments
A nozzle for dispensing a random pattern of liquid adhesive filaments. The nozzle may include first and second air shim plates, an adhesive shim plate and first and second separating shim plates. The first and second air shim plates each have respective pairs of air slots. Each air slot has a process air inlet and a process air outlet and the air slots of each pair converge toward one another such that the process air inlets are farther apart than the process air outlets in each pair. The adhesive shim plate includes a plurality of liquid slots each with a liquid outlet. Four process air outlets are associated with each of the liquid outlets. The process air slots are adapted to receive pressurized process air and the liquid slots are adapted to receive pressurized liquid adhesive. The pressurized process air discharges from each group of the four process air outlets and forms a zone of turbulence for moving the filament of liquid adhesive discharging from the associated liquid outlet in a random pattern. |
| US08399051B1 |
Method for making a patterned perpendicular magnetic recording disk having a FePt or CoPt chemically ordered recording layer
A method for making a bit-patterned-media (BPM) magnetic recording disk includes depositing a FePt (or CoPt) alloy recording layer, and then depositing a sealing layer on the FePt layer before high-temperature annealing. The high-temperature annealing causes the FePt to become substantially chemically-ordered in the L10 phase. After annealing, the sealing layer is removed. The sealing layer prevents nanoclustering and agglomeration of the FePt material at the surface of the FePt layer and the sealing layer, which would result in undesirable high surface roughness of the FePt, making patterning of the FePt layer difficult. The FePt layer can be patterned into the discrete islands for the BPM disk either before deposition of the sealing layer or after deposition and removal of the sealing layer. After patterning and removal of the sealing layer, the disk protective overcoat is deposited over the discrete data islands. |
| US08399042B2 |
Water-dispersable sterol containing dispersions
The invention relates to aqueous dispersions containing (a) 5 to 50% by weight of sterols and/or stanols; and (b) 0.5 to 20% by weight of citric acid esters of mono- and/or diglycerides, based on the total weight of the dispersion, wherein the citric acid esters of mono- and/or diglycerides are partially neutralised; and to a process for the production of an aqueous sterol/stanol-containing dispersion, which process comprises (a) dissolving citric acid esters of mono- and/or diglycerides that are partly neutralised, in water; (b) dispersing sterols and/or stanols in the emulsifier solution to form a pre-dispersion; and (c) grinding the pre-dispersion in a ball-mill until the dispersion has a particle mass diameter, d90, of less than 5 μm. Optionally, this dispersion is spray-dried. |
| US08399036B2 |
Layered taco maker and method
A method for filling an edible shell, in particular, a taco shell is achieved by gathering a first filling ingredient for a taco and layering the first filling ingredient along a first plane, gathering a second filling ingredient for a taco and layering the second filling ingredient along a second plane substantially parallel to the first plane, and inserting the layered first and second filling ingredients within a taco shell. A template for the preparation of a layered taco is also provided. The template includes a guide member having a concave recess shaped and dimensioned for receiving the open end of a taco shell, the concave recess being defined by a facing wall in the generally shape of the open end of the taco shell. The template also includes a support shelf transversely positioned within the concave recess. At least one filling ingredient is placed upon the support shelf, the taco shell is slid within the concave section with the filling ingredient between the first and second shell walls and the support shelf is withdrawn such that the filling ingredient is released to lie within the taco shell. |
| US08399035B2 |
Pod for dispersible materials
A pod for mixing an amount of a dispersible material with water. The pod may include a pod body having a lower aperture and a poppet positioned within the aperture. The poppet may be sized so as to seal the lower aperture until a predetermined pressure is reached within the pod body. |
| US08399033B2 |
Anti-bacterial composition comprising extract from barks of Alnus pendula Matsum
The present invention relates to a composition for treating a bacterial infection comprising an extract from a bark of Alnus pendula, or diarylheptanoid compound as an active ingredient. The extract from a bark of Alnus pendula, diarylheptanoid compound of the present composition has a remarkably excellent anti-bacterial activity against bacteria, specifically Staphylococcus aureus. Therefore, the extract and compound of the present invention may be utilized as an active ingredient of drug, cosmetics, functional food and animal feed for treating bacterial infection, in particular an infection of S. aureus. |
| US08399031B1 |
Compositions and methods for restoring pulmonary function
This invention relates to compositions and methods that restore pulmonary function, preferably inhibiting or arresting the constriction of the bronchial tubes when administered to mammals, including humans. The pulmonary restorative composition for improving respiratory health comprises an effective amount of Gnaphalium obtusifolium L., more commonly known as rabbit tobacco, sweet everlasting and other historical names; Liquidambar, more commonly known as sweet gum; and Verbascum, more commonly known as mullein. Optionally, the composition may include at least of one additional herbal nutrient selected from the group Prunus avium, more commonly known as wild cherry; Althaea officinalis, more commonly known as marshmallow or mallow; Prunus amygdalus, more commonly known as peach; and Eucalyptus; and may include glucose. Also disclosed are methods for restoring or maintaining pulmonary function by the administration of the composition of the invention. |
| US08399030B1 |
Skin treatment compositions and methods of use
A new use of castor oil in treating atopic eczema and cradle cap is disclosed. Compositions of greater than 50% castor oil and less than 50% mineral oil are preferable for skin application. Compositions of approximately 80% castor oil and 20% mineral oil are optimal for skin application. The compositions are best applied using a small pump-spray bottle (optimally about 2 oz.) having a relatively small output aperture (optimally about 3 mm). The spray application and composition reduced the messiness of the application process.The composition is applied differently to different conditions; specifically the composition is applied to atopic eczema and dry or non-oily cradle cap and left in place to be absorbed into the patient's skin; to oily cradle cap, the composition is optimally applied for a period of about 5 minutes, after which the scalp is massaged and the patient's scabs or flakes are removed along with the composition. |
| US08399026B2 |
Peptides isolated from spider venom, and uses thereof
The presently described subject matter relates to isolated spider venom peptides, which are used as potent and selective ion channel blockers, and to a composition and methods for treatment of pain. |
| US08399025B2 |
Polyamine modified particles
A particle composition comprising a graft copolymer formed from a biocompatible polymer and a plurality of polyamine moieties, wherein the polyamine moieties are bound to the biocompatible polymer, and a combinatorial delivery polymer comprising a plurality of particles that comprises a graft copolymer of formed from a biocompatible polymer and a plurality of polyamine moieties, wherein the polyamine moieties are bound to the biocompatible polymer, a plurality of nucleic acids electrostatically loaded onto the particles, a plurality of chemokine molecules, and a biodegradable polymer network, in which the loaded particles and chemokine molecules may be entrapped, are disclosed. Also disclosed is a method for treating a subject comprising administering a therapeutically effective dose of a pharmaceutical composition, the pharmaceutical composition comprising a particle composition that comprises a graft copolymer formed from a biocompatible polymer and a plurality of polyamine moieties, wherein the polyamine moieties are bound to the biocompatible polymer. |
| US08399024B2 |
Water-insoluble medicine
A method of producing water-insoluble anti-cancer drug in the form of particulates, the method including preparing a water-insoluble anti-cancer drug having at least one multiple bond in the structure, and irradiating said water-insoluble anti-cancer drug with a laser beam having a wavelength of a low absorption portion in the vicinity of the foot of an absorption curve on the long wavelength side within the absorption band until said water-insoluble anti-cancer drug is formed into particulates having an average particle diameter of 50 to 200 nm. |
| US08399022B2 |
Spherical ferrite nanoparticles and method for producing the same
A method for producing spherical ferrite nanoparticles includes the steps of: preparing a first aqueous solution containing a disaccharide, an alkaline, an oxidation agent, seed particles and divalent iron ions; and conducting particle growth in the first aqueous solution to produce the spherical ferrite nanoparticles. |
| US08399020B2 |
Shaped plant growth nutrient products and processes for the production thereof
Shaped plant growth nutrient products such as fertilizer products are provided as well as processes for producing and using such shaped plant growth products. The products comprise active plant growth ingredients mixed with a biodegradable, water dispersible, water soluble, thermoplastic polymeric binding agent. Preferably, the shaped products are in tablet form and the active plant growth ingredient comprises a fertilizer. |
| US08399018B2 |
Controlled release ion channel modulator compositions and methods for the treatment of otic disorders
Disclosed herein are compositions and methods for the treatment of otic disorders with ion channel modulators. In these methods, the ion channel modulator compositions and formulations are administered locally to an individual afflicted with an otic disorder, through direct application of the ion channel modulator compositions and formulations onto the auris interna target areas, or via perfusion into the auris interna structures. |
| US08399017B2 |
Use of a matrix for orally administering sustained release magnesium, and composition containing said matrix
A tablet for oral administration comprises a matrix of progressive and continuous released magnesium. For the administration of 90 to 110 parts by weight of magnesium, the matrix comprises 180 to 190 parts by weight of hydroxypropylmethylcellulose, 19.8 to 22.2 parts by weight of glyceryl behenate, 10 to 12 parts by weight of lactose and 10 to 12 parts by weight of colloidal silica. A non-enteric protective coating that slows down the gastric dissolution of the magnesium may comprise 15 to 75 parts by weight of shellac, cellulose ether or a mixture thereof. The tablet may be administered to patients in need thereof. |
| US08399016B2 |
Sustained-release tablet composition of pramipexole
A sustained-release pharmaceutical composition in a form of an orally deliverable tablet comprises a water-soluble salt of pramipexole, dispersed in a matrix comprising a hydrophilic polymer and a starch having a tensile strength of at least about 0.15 kN cm−2 at a solid fraction representative of the tablet. |
| US08399014B2 |
Physiologically active complex comprising protamine and/or salt therefor and an acidic macromolecular substance, and use thereof
To provide a method of reducing an intrinsic harsh/astringent taste of protamine and a protamine salt and effectively using a fat absorption suppressive effect of these.A complex is formed by reacting at least one of acidic macromolecular substances, such as alginate and polyglutamate, and gum arabic which are capable of forming a complex reducing harsh/astringent taste and dissociating protamine having a lipase inhibitory activity by pepsin treatment, with protamine or a protamine salt. |
| US08399013B2 |
Partially absorbable fiber-reinforced composites for controlled drug delivery
This invention describes a partially absorbable, fiber-reinforced composite in the form of a ring, or a suture-like thread, with modified terminals for use as a controlled delivery system of at least one bioactive agent, wherein said composite comprising an absorbable fiber construct capable of providing time-dependent mechanical properties of a biostable elastomeric matrix containing an absorbable microparticulate ion-exchanger to modulate the release of the bioactive agent(s) for a desired period(s) of time at a specific biological site; this can be a vaginal canal, peritoneal cavity, scrotum, prostate gland, an ear loop or subcutaneous tissue. Such drug delivery systems can be used for the local administration of at least one bioactive agent, including those used as contraceptive, antimicrobial, anti-inflammatory and/or antiviral agents as well as for cancer treatment. |
| US08399012B2 |
Degradable therapeutic delivery device
A biodegradable biodelivery device is disclosed. The biodelivery device is formed from a polymer comprising the reaction product of a polyol and a polyacid. When exposed to water, the polymer degrades through hydrolysis. Of particular advantage, the polymer can be formed so as to be elastic and flexible. In one embodiment, the polymer is formed into a vaginal insert. As the polymer degrades, the polymer releases acid to a vaginal environment for decreasing the pH of the environment. |
| US08399011B1 |
Oral particle compositions containing a core and an acid-soluble coat
The present invention relates to an oral particle composition as an ingredient in an extended-release tablet formulation, comprising a core and a coat, wherein the coat is acid-soluble. |
| US08399006B2 |
Posterior segment drug delivery
A therapeutic device to release a therapeutic agent comprises a porous structure coupled to a container comprising a reservoir. The reservoir comprises a volume sized to release therapeutic amounts of the therapeutic agent for an extended time when coupled to the porous structure and implanted in the patient. The porous structure may comprise a first side coupled to the reservoir and a second side to couple to the patient to release the therapeutic agent. A plurality of interconnecting channels can extend from the first side to the second side so as to connect a first a plurality of openings on the first side with a second plurality of openings on the second side. Each of the openings on the first side can be connected to each of the openings on the second side with the plurality of interconnecting channels, such that the rate of release of the therapeutic agent can be substantially maintained when one or more of the openings is blocked, for example with particles, cells, bacteria or tissue when the device is implanted for an extended time. The length of the channels extending from the first side to the second side may comprise an effective length greater than a distance across the porous structure from the first side to the second side. The therapeutic device many comprise an expandable retention structure and an expandable reservoir, such that the device can be delivered from a lumen of a delivery device and expand when positioned in the patient. The therapeutic device may comprises a penetrable barrier to inject therapeutic agent into the device when implanted in the patient. |
| US08399005B2 |
Use of nitric oxide to enhance the efficacy of silver and other topical wound care agents
The present invention is directed to compositions comprising at least one nitric oxide donor and at least one second therapeutically active agent with antimicrobial or wound healing capability. In one embodiment, the nitric oxide donor is a nanoparticle which is designed to control for the amount and duration of release of nitric oxide. The nanoparticle may further comprise the additional therapeutically active agent. The composition is useful for enhancing wound healing and for treating and preventing microbial infection. In one embodiment, the composition is directed toward reducing oral bacteria or dental plaque. The combination of one or more nitric oxide donors and one or more additional therapeutically active agent results in unexpected synergistic effects, wherein both the antimicrobial efficacy of the nitric oxide and the antimicrobial or wound healing efficacy of the second therapeutically active agent are enhanced. As a result, a patient may benefit from reduced dosage requirements and a reduced likelihood of antimicrobial resistance. The composition may be formulated for local or systemic administration, for topical applications as well as for use in coatings for medical supplies and devices. |
| US08399004B2 |
Lipid carriers
There is disclosed a method of controlling pests which comprises exposing a surface of the pest to a particulate composition containing particles of an initially unmagnetized material, which is capable of becoming magnetically polarized when subjected to an electric or magnetic field, the said particles being associated with at least one pesticide or behavior modifying chemical. |
| US08399003B2 |
Formulations and methods employing anhydrous disinfectant
Use of dried compositions of silver dihydrogen citrate along with citric acid in antimicrobial amounts directly as disinfectants is described. |
| US08399001B2 |
Cosmetic composition comprising at least one gellan gum or derivative thereof, at least one monovalent salt, and at least one suspension compound, processes using this composition, and uses thereof
Disclosed herein is a liquid or fluid aqueous cosmetic composition comprising, in a cosmetically acceptable medium, at least one gellan gum or derivative thereof, at least one monovalent salt, and at least one suspension compound chosen from silicones and fatty substances. Further disclosed herein is a process for shaping and/or holding a hairstyle, in which the cosmetic composition is used, as well as the uses of this cosmetic composition as a styling composition for fixing and holding the hair, a haircare composition, a hair conditioning composition for giving the hair softness, and a hair makeup composition. |
| US08398988B2 |
Adjuvanting meningococcal factor H binding protein
Factor H binding protein (fHBP) has been proposed for use in immunising against serogroup B meningococcus (‘MenB’). This antigen can be efficiently adsorbed to an aluminum hydroxyphosphate adjuvant by (i) ensuring that adsorption takes place at a pH which is equal to or below the adjuvant's point of zero charge (PZC), and/or (ii) selecting a fHBP and adjuvant with an isoelectric point/PZC within the range of 5.0 to 7, and/or (iii) selecting a fHBP with an isoelectric point above the adjuvant's PZC and using a buffer to bring the pH to within 1.2 pH units of the PZC. The adsorption is particularly useful for compositions which include multiple fHBP variants, and also in situations where an aluminum hydroxide adjuvant should be avoided. Buffered pharmaceutical compositions can include at least two different meningococcal fHBP antigens, both of which are at least 85% adsorbed to aluminum hydroxyphosphate adjuvant. |
| US08398987B2 |
Use of platelet glycopeptide IIIa epitopes in the treatment of immune thrombocytopenic purpura
The present invention relates to a composition for treating diseases associated with autoantibodies specific for platelet proteins, in particular autoimmune thrombocytopenic purpura. The composition, comprising an epitope of a platelet protein, treats diseases by tolerization. |
| US08398986B2 |
ADP-ribosylating toxin from listeria monocytogenes
An ADP-ribosylating toxin from Listeria monocytogenes is disclosed, together with mutant toxins and uses therefor. There is only a low level of sequence identity between this toxin and known toxins such as the iota toxin from Clostridium perfringens. |
| US08398984B2 |
Removal promoters and inhibitor for apoptosis cells in vivo
The present invention is to provide a removal promoter for apoptotic cells which is capable of immediately removing apoptotic cells in vivo by macrophages, or a removal inhibitor which inhibits the removal of apoptotic cells in vivo by macrophages. A removal promoter for apoptotic cells in vivo containing the milk fat globule-EGF factor 8-L (MFG-E8-L), MFG-E8-L mutant having removal promotion action for apoptotic cells in vivo by macrophages, or preferably a recombinant human or mouse MFG-E8-L, or a recombinant human or mouse MFG-E8-L mutant as an active ingredient is prepared. Such removal promoters specifically bind to apoptotic cells and promote the phagocytosis of apoptotic cells by macrophages by recognizing aminophospholipids such as phosphatidylserine exposed on apoptotic cell surface. On the other hand, a point mutation (D89E) MFG-E8-L mutant is used as a removal inhibitor. |
| US08398979B2 |
Polypeptides, antibody variable domains and antagonists
The invention relates to anti-TNFR1 polypeptides and antibody single variable domains (dAbs) that are resistant to degradation by a protease, as well as antagonists comprising these. The polypeptides, dAbs and antagonists are useful for as therapeutics and/or prophylactics that are likely to encounter proteases when administered to a patient, for example for pulmonary administration, oral administration, delivery to the lung and delivery to the GI tract of a patient, as well as for treating inflammatory disease, such as arthritis or COPD. |
| US08398978B2 |
Antibodies directed against amyloid-beta peptide and methods using same
Methods of using antibodies directed to the C-terminal side of β-amyloid peptide for diagnosing and treatment of Alzheimer's disease and Aβ peptide associated diseases are described. |
| US08398971B2 |
Methods, compounds, and compositions for treatment and prophylaxis in the respiratory tract
The present invention provides a method of reducing the quanitity of mucus in the respiratory tract of a subject with elevated levels of mucus in said respiratory tract. The method includes administering to the subject a compound or composition containing a therapeutically effective amount of a fusion protein comprising a sialidase or an active portion thereof and an anchoring domain. The therapeutically effective amount comprises an amount of the fusion protein that results in a reduction of the quanitity of mucus in the respiratory tract after administration of the compound or composition when compared to the quantity of mucus present prior to administration of the compound or composition. |
| US08398967B2 |
Particle formulations for use in pharmaceutical compositions
A liquid composition in an osmotic drug delivery system and a dosage form in an osmotic drug delivery system is disclosed comprising an amphiphilic molecule, a non-aqueous liquid solvent, and a pharmaceutically active agent. |
| US08398964B2 |
Organopolysiloxane having amide group, and cosmetic material containing same
Provided are an organopolysiloxane that exhibits good dispersion stability within not only organic oil agents but also cosmetic materials that contain a powder, and is able to produce a cosmetic material that exhibits excellent skin affinity, an organopolysiloxane that does not impart a sticky feeling, and exhibits excellent skin affinity and skin adhesion, and a cosmetic material including such an organopolysiloxane. The organopolysiloxane is represented by formula (1) below: in which R1 represents a hydrocarbon group such as an alkyl group, R2 represents a group represented by formula (3) or formula (4) below: in which either R4 represents a specific hydrocarbon group and R5 represents a hydrogen atom or a specific hydrocarbon group, or alternatively, at least one of R4 and R5 represents a hydroxyalkyl group, and A represents a group containing an organosilyl group or organosiloxane residue. |
| US08398963B2 |
Cosmetic agent
The present invention relates to a cosmetic composition containing at least one water-soluble or water-dispersible polymer which has, in incorporated form, a) 5 to 50% by weight of an α,β-ethylenically unsaturated monomer of the formula I where R1 and X1 are defined herein, b) 25 to 90% by weight an N-vinylamide and/or N-vinyllactam, c) 0.5 to 30% by weight of a compound having a free-radically polymerizable, α,β-ethylenically unsaturated double bond and a cationogenic and/or cationic group per molecule, and d) 0 to 30% by weight of an α,β-ethylenically unsaturated monomer of the formula II where R3, X2, and R4 are defined herein, and the salts thereof. |
| US08398959B2 |
Compositions and methods for imparting a sunless tan with functionalized adjuvants
Described are compositions and methods for imparting a sunless tan with functionalized adjuvants and a tanning agent like dihydroxyacetone. The functionalized adjuvants are pyrrole and/or indole derivatives functionalized with a substituent comprising a carbonyl group. |