Document Document Title
US08368578B2 Asynchronous digital slope analog-to-digital converter and method thereof
The present invention is related to an analog to digital converter circuit. The circuit comprises at least one input node for applying an analog input voltage signal (Vin), means for sampling said analog input voltage signal, a first array of capacitors arranged for receiving the sampled analog input voltage signal, a digital delay line connected to the first array of capacitors and arranged for being enabled by a clock generator and for generating a staircase or slope function by means of the first capacitor array, taking into account the sampled analog input voltage signal, a comparator arranged for comparing a converted signal with a reference voltage (Vref), said converted signal being a version of said sampled analog input voltage converted according to said staircase or slope function, and for generating a stop signal based on the comparison result thereby latching the digital delay line and thereby acquiring the digital code.
US08368574B1 Dynamic range ADC's
A Sigma-Delta analog-to-digital converter (ADC) having a direct time filter (DTF) in the feed-back path of the Sigma-Delta loop of the ADC. A Sigma-Delta ADC having a modified DTF in the feed-back path of the Sigma-Delta loop of the ADC is also disclosed. The ADC may also include a noise reduction block that splits an incoming RF signal, samples one of the split signals with a primary ADC, corrects for gain and delay inaccuracies and inverts the signal, applies the inverted signal to a primary digital-to-analog converter (DAC), combines the output of the DAC with the second split signal, which is then applied to a difference ADC.
US08368572B2 Detecting device
A detecting device has: a detecting element to which a first constant voltage is applied; a resistance element connected to the detecting element; a switching element having a first terminal to the resistance element, a second terminal controlled to a second constant voltage lower than the first constant voltage, and a control terminal sets the first terminal and the second terminal in a conducting state; a control unit, according to a conducting/non-conducting state, controls voltage to the control terminal to maintain a potential difference between the detecting element and the resistance element; and an AD converter converting, into a digital value, a potential of a potential difference between the first constant voltage and the first terminal being voltage-divided at the detecting element and the resistance element to the detecting element, a first reference potential is the first constant voltage, and a second reference potential is voltage to the first terminal.
US08368571B2 Pipelined ADC having error correction
A pipeline stage of a pipelined analog-to-digital converter (ADC) circuit can include an ADC to convert an analog input to a digital output, a first plurality of digital-to-analog converters (DACs) sufficient in number to produce an analog output corresponding to the digital output, and a second plurality of DACs configured to have their output added into the analog output, where a succeeding pipeline portion can convert the amplified analog residue to at least one second digital output and a digitized residue. A mapping circuit can selectively exchange inputs between a selected one of the first plurality of DACs and one of the second plurality of DACs, and a calibration signal circuit can provide first and second calibration signals to inputs of the selected one of the first plurality of DACs and another of the second plurality of DACs. The calibration signals can be correlated to each other, but uncorrelated to the analog input and digital output of the first pipeline stage, and have unequal effects on the amplified analog residue or the digitized residue. A correction circuit can correct the digital output of the pipeline stage for circuit path errors in circuit paths including the first plurality and second plurality of DACs based on the results of a correlation between the calibration signals and the second digital output or digitized residue. The effects, on the amplified analog residue or the digitized residue, of the first and second calibration signals, upon travelling through the selected one of the first plurality of DACs and the other of the second plurality of DACs, can at least partially offset each other.
US08368569B2 Data converting device, program and method
A data conversion device is provided with a data converting means that sequentially converts first data into second data of the number of second bits, wherein an analog signal is quantized into the first data by the number of first bits, and the first and second data can be first and second maximum values, respectively. The data converting means is comprised of a first conversion means (steps 21 and 23) that, when a value of the fast data is not the first maximum value, converts the first data to the second data by adding 0 to a lower bit side of the first data and a second conversion means (steps 21 and 24-26) that converts the first data to the second data so that, when a value of the first data is the fast maximum value, a value can be made larger, in accordance with a value be-fore or after the first data, than the data of the number of second bits obtained by adding 0 to the lower bit side of the first data. With the structure, when the data obtained by quantizing an analog signal is converted to data with the number of more bits, a rounding error by quantizing is improved as much as possible.
US08368566B2 Method and system for providing a haptic computer interface
A method and system of an embodiment may include a system comprising a touch screen display panel, and a tactile panel with one or more raised surfaces wherein the touch screen display panel is positioned on top of the tactile panel and the tactile panel creates one or more raised surfaces on the touch screen display panel providing tactile information to a user of the touch screen display panel.
US08368565B2 Power saving method in sleep mode and keyboard controller using the same
The invention relates to a power saving method in a sleep mode and a keyboard controller using the same. The method is adapted for a triangular-type scan keyboard controller including a plurality of input/output (I/O) pins. The method includes the steps of: providing a first clock source and a second clock source, wherein the frequency of the second clock source is much lower than the frequency of the first clock source. In a normal mode, a scan pulse is sequentially outputted from the I/O pins according to the frequency of the first clock source. In a sleep mode, the scan pulse is sequentially outputted from the I/O pins according to the frequency of the second clock source. When a specific one of the I/O pins outputs the scan pulse, the other I/O pins are used for detecting.
US08368560B2 Automated warning system for waterski boats
There is provided an automated warning system which includes a receiver/controller, an actuator, one or more relays electrically connected to both the receiver and the linear actuator, a flag holder and a mechanical linkage connecting the linear actuator to the flag holder such that movement of the linear actuator causes the flag holder to move between raised and lowered positions.
US08368557B2 Information device for the adapted presentation of information in a vehicle
Information for a vehicle driver is transmitted to the vehicle by vehicle-to-vehicle or vehicle-to-infrastructure communication and is individually conditioned in the vehicle in line with the respective needs of the driver. The conditioned information is then presented visually and/or audibly.
US08368551B2 Scanner for vibration mapping
A method of detecting motion in components that form part of a structure. The method includes flooding a first component with transmitted radio frequency signals and receiving reflected radio frequency signals from the first component with an antenna. The method further includes generating a first set of intermediate frequency signals based on differences between the transmitted radio frequency signals and the reflected radio frequency signals and measuring the first set of intermediate frequency signals. The method further includes flooding a second component with transmitted radio frequency signals and receiving reflected radio frequency signals from the second component with an antenna. The method further includes generating a second set of intermediate frequency signals based on differences between the transmitted radio frequency signals and the additional reflected radio frequency signals and measuring the second set of intermediate frequency.
US08368550B2 Fault detection system with redundant product teach verification
Some embodiments for a fault detection apparatus may include one or more monitors to detect at least three operating states of a sensor, such as pass, fail, and inoperative so as to enable a manufacturing facility to differentiate between situations in which a container does not have the appropriate machine readable label and situations wherein the sensor is actually inoperative. The fail state may be indicative of an object on a conveyor system not matching a predetermined description, identity or characteristic. The pass state may be indicative of an object on a conveyor system matching the predetermined description, identity or characteristic. The inoperative state may be indicative of a sensor output associated with a malfunction in the sensor itself. The fault detection apparatus may also include a fail-to-safe controller configured to detect these operating states.
US08368549B2 Telematics unit and method for controlling telematics unit for a vehicle
A telematics unit is provided for a vehicle having a power unit, along with a method for controlling a telematics unit for a vehicle. The telematics unit includes a voltage sensor, a global positioning system unit, and a processor. The voltage sensor senses a measure of a voltage of the power unit. The global positioning system unit obtains position data as to a position of the vehicle. The processor is coupled to the voltage sensor and the global positioning system unit. The processor is configured to determine whether the voltage for the power unit has decreased using the sensed measure of the voltage, determine whether the vehicle is moving using the position data, and command the telematics unit to an off mode if the voltage has decreased and the vehicle is not moving.
US08368548B2 Wireless headset and battery status indication method thereof
An enhanced wireless headset and battery status indication method is provided for indicating an accurate battery level of a wireless headset. A battery status indication method for a wireless headset determines a residual charge of a battery of the wireless headset and emits light having one of a plurality of colors from a status indication unit of the wireless headset. Each of the plurality of colors indicates a different residual charge of the battery. The wireless headset and battery status indication method also enables indicating whether the wireless headset is operating in charging mode by maintaining or blinking the battery status indication light. In addition, the wireless headset and battery status indication method enables indicating a radio communication status as well as a battery status by blinking the battery status indication light in correspondence with a communication radio scanning cycle.
US08368544B2 Hygiene monitoring system
A method is provided for monitoring hygiene compliance.
US08368539B2 Beverage container authenticity and provenance devices and methods
An RFID label and optional secondary security label ensures the authenticity of a beverage contained in a beverage container. The RFID label cannot be removed without destroying the RFID label or rendering it inoperable. A secondary security label may be placed over the closure of the beverage container to provide a secondary measure against tampering as well as a visual indicator of authenticity. It is placed on a portion of the bottle, a portion of the beverage container's closure, and the RFID label. An attempt to remove the secondary security label will also render the RFID label unusable.
US08368538B2 Method of making an RFID label
The invention relates to method for producing an RFID label. According to said method, a coupling antenna (2) arranged on a web-shaped support material (1) comprising an RFID chip (4) arranged thereon is glued onto a secondary antenna (10). The aim of the invention is to provide an RFID label that can be produced from few recyclable materials with little complication and in an environmentally friendly manner. The invention is characterized in that first the coupling antenna (2) comprising the chip (4) is glued onto a self-adhesive secondary antenna (10) in one step, the secondary antenna having a backing adhesive layer (12).
US08368533B1 System and method for facilitating connection of fiber optic data communication systems
A system for data communication connection in an architecture including an optical fiber communication line running from a communication service provider source to a proximity of at least one building, a fiber optic branch line extending from a point along the communication line generally towards the at least one building, and a receptacle, comprises a communication unit, a fiber optic cable coupled to the communication unit, and at least one connector adapted to couple the branch line to the fiber optic cable coupled to the communication unit. The connector may reside within the receptacle, and at least one of the communication unit, the cable, the branch line, the connector, and the receptacle may provide a visual indication that coupling of the branch line and the cable is effected.
US08368531B2 Method and system to control movable entities
A method to wirelessly control an entity having an attached transponder is disclosed. A geographical zone is defined. The geographical zone can be defined by allowing a user to define and load to a transponder a plurality of waypoints, each waypoint defined by a geographical coordinate and a radius originating from the geographical coordinate. The geographical zone can also be defined by selecting a plurality of coordinates that are loaded to a transponder and mapped on a pixilated image. The microprocessor in the transponder is programmed to determine the occurrence of an event associated with the status of the entity in relation to the geographical zone. Finally, the microprocessor is configured to execute a configurable operation if the event occurs.
US08368530B1 Network directed cell broadcasts for emergency alert system
Systems and methods for providing alerts to end users of networked enabled portable devices are provided so that the end users are made aware when broadcast emergency alerts are issued. The systems and methods provide a way for a portable device to receive information about an emergency alert broadcast of which the user should be aware, e.g., from the EAS, and to notify the user of the emergency alert. A flag provides an indication the EAS should be on and the systems and method override the settings made by a user to a portable device to enable EAS reception. The user may then be automatically taken to the emergency alert information by having the portable device automatically tune to the emergency broadcast information, or the user may optionally retrieve the emergency information by tuning to the emergency broadcast channel, or the user may otherwise be presented with a reference to the emergency data (e.g., a link to the information).
US08368524B2 Tire state variables management system
The present invention provides a tire state variables management system where an external module can reliably receive data from a specific sensor module from which data is to be acquired when an external module transmits to the sensor module a command signal for requesting data transmission. Each sensor module 3 possesses a self-identifying code for distinguishing itself from other sensor modules; the command signal transmitted by the external module 2 includes the self-identifying code possessed by the sensor module 3 from which data is to be acquired; and the sensor module 3 is adapted to transmit the data only when the self-identifying code included in the command signal from the external module 2 coincides with the self-identifying code possessed by itself.
US08368523B2 Collision detection sensor for vehicle
A collision detection sensor includes an absorber, a chamber member, a pressure sensor, and a collision detection circuit. The absorber is deformed with a collision to absorb collision impact force. The absorber is located in a vehicle bumper and located in front of a bumper reinforcement in a vehicle front-rear direction. The chamber member defines a chamber room therein. The chamber member is located in the bumper and located in front of the bumper reinforcement in the vehicle front-rear direction. The pressure sensor detects pressure in the chamber room. The collision detection circuit detects the collision based on the detected pressure. A front end of the absorber is located further away from the bumper reinforcement than a front end of the chamber member in the vehicle front-rear direction.
US08368522B1 Car alert device
A car alert device featuring a microprocessor operatively connected to a transmitter; a body controller operatively connected to the microprocessor, the body controller is configured to detect if a window is open, if an interior light is on, if the headlights are on, if a door is unlocked, or if the alarm system is activated; wherein the microprocessor is configured to receive input signals from the body controller when the body controller detects the window is open or the interior light is on or the headlights are on or the door is unlocked or the alarm system is activated, wherein upon receipt of the input signals the microprocessor sends output commands to the transmitter to cause the transmitter to send alert messages to the cellular phone of the user.
US08368521B2 Information processing apparatus and information processing method
Contact detection units are attached to an information transfer device in a predetermined arrangement pattern to detect contact with a human body. Presentation units are attached to the information transfer device in a predetermined arrangement pattern to present a tactile stimulus. A contact detection unit that has detected contact is specified. Based on the arrangement distribution of the specified contact detection unit and a type of information to be presented via a tactile stimulus, a presentation unit to be driven is specified. The specified presentation unit is driven and controlled.
US08368517B2 RFID privacy-preserving authentication system and method
A system and method for RFID privacy-preserving authentication is disclosed. The method first has a reader sending a request and a first random number to a tag. The tag then generates a second random number. A plurality of hash values are then computed at the tag. Each hash value uses the first random number, the second random number and at least one part of a key of the tag as inputs. The second random number and the computed hash values are then sent to the reader. Lastly, the reader identifies a validity of the tag from the received values. The hash values are all generated in parallel and are independent to each other.
US08368512B2 RFID tag, method of manufacturing the RFID tag, and method of mounting the RFID tag
An RFID tag is characterized in that it includes: a dielectric substrate; a ground conductor portion disposed on one main surface of this dielectric substrate; a patch conductor portion disposed on another main surface of the above-mentioned dielectric substrate and forming a slot; electrical connecting portions internally extending from opposing sides of the above-mentioned slot, respectively; and an IC chip placed in the above-mentioned slot and connected to the above-mentioned electrical connecting portions.
US08368510B2 Biometric authentication and verification
Biometric authentication and verification are described. A method in biometric identification includes establishing a foundational biometric measurement based on a first user input. The method also includes providing a second user input at a biometric terminal, the second user input used by the biometric terminal to determine whether to acknowledge a verifying biometric measurement, in response to receipt of the established foundational biometric measurement and the second user input. The method may also include establishing the foundational biometric measurement, by the user, utilizing biometric equipment. Alternatively, the establishing of the foundational biometric measurement based on first user input is performed by providing the first user input to a biometric kiosk, the biometric kiosk using the first user input to establish the foundational biometric measurement. Advantages of the present invention include the ability to perform more secure biometric transactions.
US08368504B1 Positive temperature coefficient circuit protection device
A PTC circuit protection device includes a PTC polymer material and two electrodes attached to the PTC polymer material. The PTC polymer material includes a polymer matrix and a particulate conductive filler dispersed in the polymer matrix. The polymermatrix is made from a polymer composition that contains a primary polymer unit and a reinforcing polyolefin. The primary polymer unit contains a base polyolefin and optionally a grafted polyolefin. The reinforcing polyolefin has a weight average molecular weight greater than that of the base polyolefin. The primary polymer unit and the reinforcing polyolefin are co-melted together and then solidified to form the polymer matrix. The base polyolefin has a melt flow rate ranging from 10 g/10 min to 100 g/10 min, and the reinforcing polyolefin has a melt flow rate ranging from 0.01 g/10 min to 1 g/10 min.
US08368503B2 Temperature sensor and method for adjusting such a temperature sensor
A temperature sensor for a radiant heater has a first tubular expansion element which is connected to its housing and contains a second rod-like expansion element, the two expansion elements having different coefficients of thermal expansion. The temperature sensor has two switching springs for different switching points. In order to adjust a second switching spring, which is fastened to a second switching spring base, the second switching spring base can be moved in the longitudinal direction of the rod and is then permanently fixed by bending or welding.
US08368501B2 Integrated inductors
Multiple-inductor embodiments for use in substrates are provided herein.
US08368500B2 Form-less electronic device assemblies and methods of operation
Improved form-less electronic apparatus and methods for manufacturing the same. In one exemplary embodiment, the apparatus comprises a shape-core inductive device having a bonded-wire coil which is formed and maintained within the device without resort to a bobbin or other form(er). The absence of the bobbin simplifies the manufacture of the device, reduces its cost, and allows it to be made more compact (or alternatively additional functionality to be disposed therein). One variant utilizes a termination header for mating to a PCB or other assembly, while another totally avoids the use of the header by directly mating to the PCB. Multi-core variants and methods of manufacturing are also disclosed.
US08368497B2 Transformer assembly with enhanced air cooling
A cooling system for a transformer comprises a fan duct and a housing which together enclose an interior space. A transformer located in the interior space is mounted on the fan duct, and has a plurality of core sections surrounded by windings and separated by gaps. An air channeling structure is located between the transformer and the fan duct. A cooling airflow path extends through the air channeling structure, and between core sections of the transformer.
US08368496B2 Permanent magnet having improved field quality and apparatus employing the same
A ring magnet assembly has a generally cylindrical magnet body defining an air gap having an upper end and a lower end. Upper and lower face plates dispose respectively at an upper portion of the ring magnet and lower portion of the ring magnet. The face plates preferably have a high magnetic permeability. A mass analyzer may be disposed within the air gap. An ion generator may be disposed within an air gap of a ring magnetic assembly of the present invention. A pair of vertically-stacked magnetic ring assemblies may be provided. In that embodiment, a mass analyzer may be disposed within one air gap and an ion generator within another.
US08368494B2 Magnetic coupling device
A hand-actuated magnetic coupling or closing device, consisting of elements that are integrally connected either to the objects that are to be coupled or applied to the objects. The coupling device comprises the following characteristics: Elements are coupled together by means of a coupling element; the coupling element can be displaced in two degrees of freedom; in the first degree of freedom, the coupling element can be displaced about the play between a coupling position and a decoupling position; in the second degree of freedom, the coupling element can be moved in a sliding manner by means of an input actuation. A magnetic element is arranged and a magnetic system is arranged in the coupling element. In the second degree of freedom and by means of the input actuation, the coupling element is displaced from the coupling position, in which the coupling element is attracted into the decoupling position, in which the coupling element is repelled and displaced about the play in the first degree of freedom.
US08368492B1 Bidirectional direct current electrical switching apparatus
A direct current electrical switching apparatus includes a first contact in electrical communication with first and third arc runners, a second contact in electrical communication with second and fourth arc runners, a movable contact, a first arc chamber including first arc plates having a first width, a second arc chamber including second arc plates having a greater second width, an operating mechanism, and a magnet assembly cooperating with the arc chambers to establish generally oppositely directed magnetic fields. The magnetic fields cause one of a first arc and a second arc to enter one of the arc chambers depending upon a direction of current flow between the contacts. The electrical switching apparatus is rated for a first magnitude of current flowing from the first contact to the second contact and for a greater second magnitude of opposite second current flowing from the second contact to the first contact.
US08368488B2 Electromagnetic bandgap structure and printed circuit board
An electromagnetic bandgap structure and a printed circuit board that can solve a mixed signal problem between an analog circuit and a digital circuit are disclosed. In accordance with an embodiment of the present invention, an electromagnetic bandgap structure is stacked with a first metal layer, a first dielectric layer, a metal plate, a second dielectric layer and a second metal layer, and an odd number of vias can be serially connected through a metal line between the first metal layer and the metal plate. This electromagnetic bandgap structure can have a small size and a low bandgap frequency.
US08368487B1 Thin-film bulk acoustic resonators having multi-axis acoustic wave propagation therein
Microelectromechanical resonators include a resonator body anchored to a surrounding substrate by at least one support that holds the resonator body opposite a recess in the substrate. The resonator body has first and second pluralities of interdigitated drive and sense electrodes thereon. The first plurality of interdigitated drive and second electrodes are aligned to a first axis of acoustic wave propagation in the resonator body when the resonator body is operating at resonance. In contrast, the second plurality of interdigitated drive and sense electrodes are aligned to a second axis of acoustic wave propagation in the resonator body. This second axis of acoustic wave propagation preferably extends at an angle in a range from 60° to 120° relative to the first axis and, more preferably, at an angle of 90° relative to the first axis. The resonator body may also be configured to have a first side that is oriented at a 45° angle relative to the first axis of acoustic wave propagation and oriented at a 45° angle relative to the second axis of acoustic wave propagation.
US08368486B2 Duplexer
A duplexer includes an acoustic wave element having a first terminal and a second terminal; a substrate; a first columnar conductor electrically connected to the first terminal, and drawn to a back surface of the substrate while partially in the substrate; a second columnar conductor electrically connected to the second terminal, and drawn to the back surface of the substrate while partially in the substrate. Additionally, a first ground pattern region is between the first columnar conductor drawn part and the second columnar conductor drawn part on the back surface of the substrate; a second ground pattern region is electrically connected to the first ground pattern region and arranged in the part not including the part between the first columnar conductor drawn part and the second columnar conductor drawn part; and a third columnar conductor electrically is connected to the first ground pattern region while partially in the substrate.
US08368477B2 Receiver including an LCD tank filter and method thereof
A receiver is provided. The receiver includes a differential amplifier amplifying differential input signals input to input terminals and outputting differential output signals through output terminals and an oscillator connected to the output terminals of the differential amplifier. The differential amplifier and the oscillator operate alternatively in response to an enable signal.
US08368476B2 Resonator element, resonator device and electronic device
A resonator element includes: a base portion, a first resonating arm that is extended from the base portion along a first direction, and a second resonating arm that is extended from the base portion along a first direction opposite to the first resonating arm, wherein the first resonating arm and the second resonating arm are arranged such that a base end portion of one side resonating arm and a middle portion of the other side resonating arm are arranged in the second direction orthogonal to the first direction.
US08368473B2 Resonator and oscillator using same
There is provided with a resonator which can correct the resonance frequency of a vibrator in a wide range and with a high accuracy and also provided with an oscillator using the resonator. In the resonator configured by the vibrator 101, electrodes 4, 5 disposed so as to oppose to parts of the surface of the vibrator 101 via gaps, and variable voltage sources 24, 25 for applying a voltage to both or one of the vibrator 101 and the electrodes 4, 5, each of the electrodes 4, 5 is configured by plural electrodes. The electrodes 4, 5 are respectively disposed via gaps close to the portions of the vibrator 101 having different vibration amplitudes. The DC voltages being applied are independently adjusted with respect to the electrodes 4, 5 which differ in distances from the shaft of the vibrator among the plural electrodes close to the vibrator 101.
US08368469B2 Silicon-on-insulator high power amplifiers
Illustrative embodiments of a power amplifier are disclosed which include a plurality of amplifier cells, each having an input and an output. The plurality of amplifier cells are formed on a semiconductor substrate such that the outputs of the plurality of amplifier cells are electrically coupled in series. Each of the plurality of amplifier cells may comprise a first transistor that is electrically insulated from the semiconductor substrate and a first feedback resistor configured to dynamically bias the first transistor.
US08368468B2 Error amplifier and LED circuit comprising the same
An error amplifier and a LED circuit comprising the same are provided. The LED circuit comprises an inductor, a group of LEDs and a power MOS connected to the inductor, an error amplifier and a pulse width modulator controlling the gate of the power MOS according to an error amplifier output. The error amplifier comprises a differential input stage, an output stage having a first NMOS, a first PMOS, a second NMOS, a second PMOS and a control switch module. During a first operation mode, the control switch module connects the first NMOS and PMOS and connects the second NMOS and PMOS, and during a second operation mode, control switch module disables the second NMOS and PMOS.
US08368466B2 Orthogonal basis function set for digital predistorter
A predistorter applies a distortion function to an input signal to predistort the input signal. The output of the distortion function is modeled as the sum of the output signals from the orthogonal basis functions weighted by corresponding weighting coefficients. Techniques are described for orthogonalizing the basis function output signals depending on the distribution of the input signal.
US08368459B2 Constant-voltage circuit
A constant-voltage circuit includes: first and second field-effect transistors; a first node connected to the drains of the first and second field-effect transistors; a second node connected to the gates of the first and second field-effect transistors; a bipolar transistor whose collector is connected to the second node; a resistor connected to the source of the second field-effect transistor and the collector of the bipolar transistor; and a bias circuit that is connected to the source of the second field-effect transistor and supplies a bias voltage to the base of the bipolar transistor, wherein a power supply is connected to the first node and a constant voltage is outputted from the source of the first field-effect transistor.
US08368455B2 Apparatus and method for automatic control of current electrodes for electrical resistivity survey
An apparatus and method for automatic control of current electrodes in a measuring system for an electrical resistivity survey. An exemplary apparatus includes: a circuit where one pair of metal oxide semiconductor field effect transistors (MOSFETs) are connected to upper and lower terminals of n current electrodes and the one pair of MOSFETs are connected in parallel with each other; and a controller which controls ON/OFF of each MOSFET.With this, the present invention provides a stable and semipermanent apparatus for automatic control of current electrodes, which is capable of bipolar high-speed switching, and a method thereof.
US08368449B1 Dead zone detection for phase adjustment
A circuit includes a phase adjustment circuit and a dead zone detect circuit. The phase adjustment circuit is operable to receive periodic signals and is operable to provide one of the periodic signals as a selected periodic signal based on a phase comparison between a data signal and the selected periodic signal. Each of the periodic signals has a different phase. The dead zone detect circuit is operable to cause the phase adjustment circuit to shift a phase of the selected periodic signal if the dead zone detect circuit determines that the data signal is in a dead zone. The dead zone detect circuit defines the dead zone based on two of the periodic signals. The phase adjustment circuit is operable to adjust a phase range of the dead zone.
US08368448B2 Delay lines, methods for delaying a signal, and delay lock loops
Locked loops, delay lines, delay circuits, and methods for delaying signals are disclosed. An example delay circuit includes a delay line including a plurality of delay stages, each delay stage having an input and further having a single inverting delay device, and also includes a two-phase exit tree coupled to the delay line and configured to provide first and second output clock signals responsive to clock signals from inputs of the delay stages of the plurality of delay stages. Another example delay circuit includes a delay line configured to provide a plurality of delayed clock signals, each of the delayed clock signals having a delay relative to a previous delayed clock signal equal to a delay of a single inverting delay device. The example delay circuit also includes a two-phase exit tree configured to provide first and second output clock signals responsive to the delayed clock signals.
US08368447B1 Delay lock loop circuit
The invention provides a delay lock loop circuit (DLL) for generating a locked signal, the DLL circuit includes: a phase detector, a first and a second voltage controlled delay chains, a charge pump and a duty cycle detection pump. The phase detector generates a phase detecting result by detecting a phase difference between the clock signal and the locked signal. The first and the second voltage controlled delay chains generate a first and a second delayed signals by delaying the clock signal according to the first and the second control signals, respectively. The charge pump is used for generating the first and the second control signal according to the phase detecting result. The duty cycle detection pump is used for controlling a voltage level of the second control signal according to the first and the second delayed signals.
US08368443B1 Differential charge pump circuit
A differential charge pump circuit including a common mode bias unit, a first single-ended charge pump unit, and a second single-ended charge pump unit is provided. The common mode bias unit provides a differential signal to a low pass filter. The first single-ended charge pump unit provides a first current to the common mode bias unit or sinks the first current from the common mode bias unit via the first terminal based on an up signal and a down signal. The second single-ended charge pump unit provides a second current to the common mode bias unit or sinks the second current from the common mode bias unit via the second terminal based on the up signal and the down signal. The first and the second single-ended charge pump units respectively charge or discharge the first and the second terminals of the common mode bias unit.
US08368439B2 Phase locked loop circuit, method of detecting lock, and system having the circuit
Provided are a phase locked loop (PLL) circuit, a lock detector employable with a PLL circuit, a system including such a PLL circuit and/or lock detector, and a method of detecting a lock/unlock state of a PLL circuit. The PLL circuit may include a clock generating circuit configured to generate an output clock signal having a predetermined frequency in synchronization with a reference clock signal. The lock detector may be configured to determine that the PLL circuit is in a lock state when a phase difference between the reference clock signal and the output clock signal is equal to or less than a first reference value, determine that the PLL circuit is in an unlock state when the phase difference between the reference clock signal and the output clock signal is greater than a second reference value, and generate a lock detection signal.
US08368437B2 Phase locked loop with charge pump
A phase locked loop (PLL) includes a voltage controlled oscillator (VCO) configured to supply an output signal. A phase frequency detector (PFD) is configured to receive a reference frequency signal and to provide a first control signal. A first charge pump is configured to receive the first control signal and to provide a first voltage signal in order to control the VCO. A second charge pump is configured to receive the first control signal and to provide a second voltage signal. A comparator is configured to receive a reference voltage signal, to compare the reference voltage signal and the second voltage signal, and to provide a second control signal. The PFD is configured to adjust at least one side slope of the first control signal based on the second control signal.
US08368435B2 Method and apparatus for jitter reduction
A low bandwidth phase lock loop (PLL) arranged in a dual-loop configuration is disclosed. The first loop is a standard loop configuration using a crystal oscillator as a reference clock. The loop parameters for this first PLL can be optimized to work over a wide range of output frequencies, and with a minimum amount of jitter. The first loop outputs a reference signal, which is a VCO output. The second loop comprises a bang-bang detector configured to drive a digital loop filter, which then drives a phase interpolator. The phase interpolator manipulates the output phase. Since phase and frequency are related, where frequency is the derivative of phase, small frequency offsets can be made using a phase control signal, generated within the second loop based on the relation between the reference signal and the clock input signal. The second loop sets the jitter transfer bandwidth of the system.
US08368434B2 Differential quadrature divide-by-three circuit with dual feedback path
A divide-by-three circuit includes a chain of three dynamic flip-flops and a feedback circuit of combinatorial logic. The divide-by-three circuit receives a clock signal that synchronously clocks each dynamic flip-flop. The feedback circuit supplies a feedback signal onto the first dynamic-flop of the chain. In a first mode, a signal from a slave stage of the first flip-flop and a signal from a slave stage of the second flip-flop are used by the feedback circuit to generate the feedback signal. In a second mode, a signal from a master stage of the first flip-flop and a signal from a master stage of the second flip-flop are used by the feedback circuit to generate the feedback signal. By proper selection of the mode, the frequency range of the overall divider is extended. Combinatorial logic converts thirty-three percent duty cycle signals from the flip-flop chain into fifty percent duty cycle quadrature signals.
US08368433B2 Transistor module and transistor driving module
The present invention discloses a transistor driving module, coupling to a converting controller, to driving a high side transistor and a low side transistor connected in series, wherein one end of the high side transistor is coupled to an input voltage and one end of the low side transistor is grounded. The transistor driving module comprises a high side driving unit, a low side driving unit, a current limiting unit and an anti-short through unit. The high side driving unit generates a high side driving signal to turn the high side transistor on according to a duty cycle signal, and the low side driving unit generates a low side driving signal turn the low side transistor on according to the high side driving signal. The current limiting unit is coupled to the high side transistor and the high side driving unit, and generates a current limiting signal when a current flowing through the high side transistor higher than a current limiting value. The high side driving unit is stopped to generate the high side driving signal when receiving the current limiting value. The anti-short through unit is coupled to the high side driving unit and the low side driving unit to control the generations of the high side driving signal and the low side driving signal to have the timings of the high side driving signal and the low side driving signal non-overlapped.
US08368428B2 Systems and methods of integrated circuit clocking
Various systems and methods are provided for integrated circuit clocking. In one embodiment, an integrated circuit system includes a plurality of combinational logic groups, each combinational logic group having a propagation time; and means for delaying a synchronizing clock signal supplied to at least one of the plurality of combinational logic groups based upon a period of the synchronizing clock signal and the propagation time of the at least one combinational logic group. In another embodiment, a method includes delaying a clock signal to produce a delayed clock signal and communicating the clock signal and the delayed clock signal to separate groups of the combinational logic circuit during a clock cycle that results in a reduction in power consumption by the combinational logic circuit.
US08368427B2 Semiconductor device, driving method thereof and electronic device
The invention provides a semiconductor device having a current input type pixel in which a signal write speed is increased and an effect of variations between adjacent transistors is reduced. When a set operation is performed (write a signal), a source-drain voltage of one of two transistors connected in series becomes quite low, thus the set operation is performed to the other transistor. In an output operation, the two transistors operate as a multi-gate transistor, therefore, a current value in the output operation can be small. In other words, a current in the set operation can be large. Therefore, an effect of intersection capacitance and wiring resistance which are parasitic on a wiring and the like do not affect much, thereby the set operation can be performed rapidly. As one transistor is used in the set operation and the output operation, an effect of variations between adjacent transistors is lessened.
US08368420B2 Method of error detection when controlling a rotating-field motor
A method is specified for fault identification when operating a rotating-field motor by means of a pulse-controlled inverter, wherein electromagnetic state variables of the rotating-field motor are determined by means of a mathematical model in space-vector form, and wherein the pulse-controlled inverter is operated electronically using space-vector variables. In this case, the invention provides that, during the operation of the rotating-field motor, the space vector of an uncontrolled state variable of the rotating-field motor is formed, in that the space vector that is formed is analyzed for a spectral component at twice the frequency of the rotating field, and in that, if the spectral component at twice the frequency is present, a partial turns short is deduced in the stator windings.
US08368419B2 Assessment of on-chip circuit based on eye-pattern asymmetry
During an asymmetry testing mode of an integrated circuit, the asymmetry of an on-chip I/O circuit is tested. In particular, a transmitter circuit in the integrated circuit transmits electrical signals, which are associated with a predefined data pattern, to a receiver circuit in the integrated circuit via a communication channel (such as a differential pair of signal lines). Then the integrated circuit generates an eye pattern using the received electrical signals, and determines an asymmetry of the eye pattern about a common reference level of the received electrical signals. Furthermore, the integrated circuit performs remedial action based on the determined asymmetry. For example, the integrated circuit may compare the determined asymmetry with a predefined asymmetry criterion and, if the asymmetry exceeds the predefined asymmetry criterion, may output a result of the comparison that indicates a failure of the asymmetry test.
US08368416B2 In-process system level test before surface mount
Methods and systems for testing an integrated circuit during an assembly process are described. The integrated circuit is received from inventory. The integrated circuit is placed in a socket on a first circuit board for system-level testing. The system-level testing is performed prior to placement and permanent attachment of the integrated circuit onto a second circuit board. Provided the integrated circuit passes the system-level testing, the placement and permanent attachment of the integrated circuit to the second circuit board is the next step following the system-level testing in the assembly process.
US08368409B2 Capacitance measurement system and method
A capacitance measurement system precharges first terminals (21-0 . . . 21-k . . . 21-n) of a plurality of capacitors (25-0 . . . 25-k . . . 25), respectively, of a CDAC (capacitor digital-to-analog converter) (23) included in a SAR (successive approximation register) converter (17) to a first voltage (VDD) and pre-charges a first terminal (3-j) of a capacitor (CSENj) to a second voltage (GND). The first terminals are coupled to the first terminal of the capacitor to redistribute charges therebetween so as to generate a first voltage on the first terminals and the first terminal of the capacitor, the first voltage being representative of a capacitance of the first capacitor (CSENj). A SAR converter converts the first voltage to a digital representation (DATA) of the capacitor. The capacitance can be a touch screen capacitance.
US08368408B2 Measuring a time period
A time period of an event is determined by charging a known value capacitor from a constant current source during the event. The resultant voltage on the capacitor is proportional to the event time period and may be calculated from the resultant voltage and known capacitance value. Capacitance is measured by charging a capacitor from a constant current source during a known time period. The resultant voltage on the capacitor is proportional to the capacitance thereof and may be calculated from the resultant voltage and known time period. A long time period event may be measured by charging a first capacitor at the start of the event and a second capacitor at the end of the event, while counting clock times therebetween. Delay of an event is done by charging voltages on first and second capacitors at beginning and end of event, while comparing voltages thereon with a reference voltage.
US08368407B2 Device for measuring the thickness of a layer of material
A device for measuring the thickness of a layer of material, the device including a reading head and control unit connected to the reading head. The reading head includes a microwave planar type sensor and an A/D converter connected to the microwave sensor and arranged in proximity of the microwave sensor.
US08368406B2 Insulation measuring apparatus
An insulation measuring apparatus having a measuring circuit including a first capacitor; a control unit that reads a voltage set on the first capacitor to decide an insulation state of a power supply, and control a path configuration of the measuring circuit; a switching section provided in a path located between the measuring circuit and the control unit; and a second capacitor provided between a ground and a path located between the switching section and the control unit. The control unit controls the path configuration of the measuring circuit, by turning ON the switching section to set a voltage corresponding to the voltage that is set on the first capacitor on the second capacitor, and then by turning OFF the switching section to read the voltage set on the second capacitor and to discharge an electric charge corresponding to the voltage being set on the first capacitor.
US08368404B2 Discharge amount measuring device and method for rotational electric machine
A discharge amount measuring device includes a power source, first and second sensors, a calibration wire, and a measuring portion. The power source applies a voltage to a coil of a rotational electric machine. The first sensor detects a current flowing through the coil. The calibration wire has an end connected to the coil. The second sensor detects a current flowing through the calibration wire. The measuring portion forms a calibration line based on a first waveform detected by the first sensor and a second waveform detected by the second sensor. The measuring portion calculates a discharge amount based on the calibration line.
US08368403B2 Logging tool having shielded triaxial antennas
The present invention relates to a downhole logging tool having on its tool body a set of co-located antennas, one or more additional antennas spaced longitudinally apart from the set of co-located antennas, an electromagnetically transparent shield circumferentially surrounding the set of co-located antennas, and an electromagnetically transparent shield circumferentially surrounding each of the one or more additional antennas. The downhole logging tool may be a wireline or while-drilling tool, and it may be an induction or propagation tool. The shields may have slots that are locally perpendicular to the windings of underlying coil antennas.
US08368398B2 Calibrating parallel MRI with cartesian continuous sampling
Example systems, methods, and apparatus control a pMRI apparatus to produce a pulse sequence having an extended acquisition window, and overlapping phase-encoding gradients and read gradients. One example method controls a pMRI apparatus to produce a trajectory having Cartesian and non-Cartesian segments that sample in a manner that satisfies the Nyquist criterion in at least one region of a volume to be imaged. The pMRI apparatus is controlled to apply radio frequency energy to the volume according to the pulse sequence and following the trajectory and to acquire MR signal from the volume in response to the application of the RF energy. The MR signal includes a first component associated with the Cartesian segment of the trajectory and a second component associated with the non-Cartesian segment of the trajectory. The example method includes calibrating a reconstruction process using Nyquist-satisfying data from the second component.
US08368389B2 Sensor unit
In a sensor of a sensor unit in which working voltage or calibration voltage is supplied through a single input end, working voltage can be stably supplied to the sensor after initial calibration. The sensor unit includes a voltage stabilizing circuit for stabilizing a voltage value of a supply power source to said working voltage, and a wiring for supplying said calibration voltage to the sensor, which are provided parallel to each other between the input end of the sensor and a power source connecting end for the sensor on the circuit board, and a switching portion which can disconnect the wiring, wherein an access hole is formed in the housing through which the switching portion is accessible to disconnect the wiring.
US08368384B2 Reduction of semiconductor stresses
A method of reducing thermal stresses of a semiconductor component in a frequency converter, an arrangement in a frequency converter, and a frequency converter, wherein the semiconductor component is attached to a cooling element for cooling the semiconductor component and one or more resistive elements are attached to the cooling element. In the method, the cooling element is heated by the one or more resistive elements attached thereto by supplying current from the frequency converter through the one or more resistive elements for obtaining an elevated lowest temperature for the semiconductor component and thereby reducing the amount of temperature change between the highest and the lowest temperatures in the semiconductor component during use of the frequency converter.
US08368382B2 Frequency characteristics measuring device
A spectrum analyzer includes: two sets of measuring units having mixers, local oscillators, and IF sections for separately measuring frequency characteristics of two input signals; a trigger control section which generates a trigger signal for specifying a measurement start timing in each of the two sets of measuring units; a sweep control section which simultaneously sends an instruction to the two local oscillators when a trigger signal is inputted and performs a sweep control so that the two local oscillators output local oscillation signals of the same frequency at the same timing. This provides a frequency characteristics measuring device which can simplify the configuration for performing a measurement and reduce the undue effort required for the measurement.
US08368379B2 Apparatus and method for monitoring output within a power strip
The present disclosure describes a PDU configured to reduce the risk of an abrupt interruption in the flow of electricity caused by a malfunctioning load or overloading of a PDU output connection. In some embodiments, a PDU is configured to enable the monitoring and control of electricity provided to one or more loads coupled to the PDU. In some embodiments, a PDU is configured to enable remote monitoring and reporting through the use of communication devices.
US08368376B2 Electronic device with power switch capable of regulating power dissipation
An electronic device with a power switch capable of regulating power dissipation includes a power supply device; a power switch, for providing an output voltage; and a current regulating circuit, which includes an adaptive control unit, for outputting a regulating signal, according to the voltage difference between the power supply device and the output voltage; and a switch control unit, for outputting a switch control signal to control the magnitude of the current through the power switch, according to the regulating signal.
US08368375B2 Switching regulator with transient control function and control circuit and method therefor
The present invention discloses a switching regulator with transient control function, and a control circuit and a method for controlling the switching regulator. The switching regulator with transient control function includes: a power conversion circuit for receiving an input voltage and converting the input voltage to an output voltage; a feedback circuit for detecting the output voltage and generating a feedback signal representing the output voltage; an output capacitor coupled to an output terminal of the power conversion circuit; and a control circuit for receiving the feedback signal and generating a control signal to control the conversion operation by the power conversion circuit accordingly, wherein the control circuit includes a voltage balancing circuit which discharges the output capacitor when the output voltage is higher than a first predetermined threshold, and charges the output capacitor when the output voltage is lower than a second predetermined threshold.
US08368374B2 Comparator type DC-DC converter using synchronous rectification method
A DC-DC converter 1 is provided with a voltage conversion unit 100 and a control unit 200. The control unit 200 includes: a comparator 20 and a trigger signal generation section 30 which generate a trigger signal when an output voltage is reduced from a reference voltage after having received a minimum off-time signal, a DLL section 40 generating a reference delay signal, a delay section 50 generating delay signals which are delayed from the trigger signal by a predetermined amount, further delayed by an on-time, still further delayed by a second dead time, and yet still further delayed by a minimum off-time, respectively, according to the reference delay signal, and a timing control section 60 determining a start time point and an end time point of an on-pulse, a start time point and an end time point of an off-pulse and also generating a minimum off-time signal, according to these delay signals.
US08368372B2 Switch mode regulator
A switch mode regulator includes a first switch for controlling a current supply to an output inductor of the regulator; a second switch for selectively providing a conductive path to ground for current flowing through the output inductor; and an inverting amplifier having an input connected to an output of the first switch and an output connected to a control input of the second switch. The switch mode regulator may alternatively include a first switch for controlling a current supply to an input inductor of the regulator; a second switch for selectively providing a conductive path to a load for current flowing through the input inductor; and an inverting amplifier having an input connected to an output of the first switch and an output connected to a control input of the second switch.
US08368371B2 Method for controlling an interleaving multiphase converter and corresponding controller
A method is provided for controlling a converter of the multiphase interleaving type. According to the method, there is detected when a change of a load applied to an output terminal of the converter occurs. When detected, all of the phases of the converter are simultaneously turned off by the generation of suitable PWM driving signals. The PWM driving signals are controlled so as to force the turn-on of the phases at the same time and to zero a time phase shift of driving of the interleaving type of the PWM driving signals. The interleaving of the driving time phase shift is recovered and a normal operation of the converter is restarted. A controller for controlling a converter of the multiphase interleaving type is also provided.
US08368366B2 Driver circuit and test apparatus
Provided is a driver circuit that outputs, from an output end, an output signal corresponding to an input signal supplied thereto, comprising an output resistance section that is provided between a constant voltage source and the output end; an output switching section that switches voltage of the output end according to the input signal; and a switching section that switches a resistance value of the output resistance section. The output resistance section includes an output resistance FET having a source/drain connection between the constant voltage source and the output end, and the switching section supplies a control voltage to a gate of the output resistance FET such that the resistance between the source and the drain of the output resistance FET switches to a designated value.
US08368362B2 Boost-forward-flyback high gain converter
A boost-forward-flyback convertor has a boost converting circuit, a forward converting circuit, a flyback converting circuit and a transformer. The boost converting circuit, the forward converting circuit and the flyback converting circuit are coupled by using elements of the boost and forward converting circuits to form the transformer. The boost-forward-flyback convertor combines benefits of conventional boost, forward and flyback convertors, specifically combines active clamping and lower power pressure to the element from the boost convertor, increases gain ratio by using the forward convertor and provides output to the load during a switch OFF-state from the combination of the flyback and boost converting circuit. The boost-forward-flyback convertor combines benefits of conventional boost, forward and flyback convertors and not only has very high gain, high converting efficiency and lower power loading for devices, but also is simple, cost less, easy to use and has a small volume.
US08368351B2 Transmission line directional awareness for a charging station
An apparatus and method for coupling a charging station to a power line segment that is terminated at a first end by a charging terminal are disclosed. The apparatus includes multiple taps coupled to the power line segment and circuitry coupled to the charging station and coupled to the multiple taps. The circuitry is configured to differentiate between communication signals propagating on the power line segment in the direction from the first end to a second end of the power line segment and communication signals propagating on the power line segment in the direction from the second end to the first end based at least in part on multiple measurements of respective phase shifts associated with different portions of a communication signal, each portion received over at least a first tap and a second tap.
US08368350B2 Control system, control device and cable connection state determining method
A vehicle-side connector included at one end of a cable through which a power source outside a vehicle feeds a power storage device, includes a signal pin, a resistive element R2 connected to the signal pin at one end, a switch connected in series to the resistive element R2 at one end and grounded at the other end, and a resistive element R3 connected in parallel to the switch. The switch changes from an ON state to an OFF state upon depression of a depression portion located on the vehicle-side connector. The vehicle includes a resistive element R4 whose one end is connectable to the signal pin and other end is grounded and a control device which determines a state of connection of the cable on the basis of a signal voltage value input from a signal line electrically connected to the signal pin.
US08368347B2 Vehicular charging system
A charging ECU causes a charger to perform quick charging until a state of charge of a power storage device reaches a predetermined state. The charging ECU causes the charger to perform additional charging during which charging progresses more slowly than the quick charging, when the state of charge comes closer to full charge than the predetermined state. The charging ECU stops charging of the power storage device by the charger when the state of charge of the power storage device reaches a charging stop threshold value during the additional charging, and stops charging of the power storage device by the charger when a time of the additional charging exceeds a predetermined time even if the state of charge of the power storage device does not reach the charging stop threshold value.
US08368346B2 Portable energy storage and charging device
Disclosed is a portable charger device that includes a chamber to hold at least one rechargeable charging battery, and at least one controller. The controller is configured to determine a first charging current level to apply to the at least one rechargeable charging battery such that the at least one rechargeable charging battery achieves a first predetermined charge that is reached within a first period of time of 15 minutes or less, apply to the at least one rechargeable charging battery a first charging current substantially equal to the determined first charging current level, determine a second charging current to apply to the one or more external rechargeable batteries, and apply to the one or more external rechargeable batteries a second charging current substantially equal to the determined second charging current level, the second charging current being drawn from the at least one rechargeable charging battery.
US08368345B2 Battery charging system for controlling the supply of charging current depending on battery temperature, a battery operated system and a method for state controlled charging
A battery charging system (15) and method for state controlled charging of a battery (12). The battery charging system comprises two parallel paths (16, 17) for supplying charging current to the battery (12) from two parallel sources of charging current, an energy source (13) and a controlled charging device (14). A control unit (18) is adapted to control the supply of charging current along the two paths in response to a detected state of the battery (12). If a state above a predetermined threshold is detected, the control unit (18) controls the supply of charging current such that the battery (12) receives charging current from the controlled charging device (14), but not directly from the energy source (13). The detected state of the battery may e.g. be a temperature state. The present invention allows for balancing the demands of high charging rate and long expected lifetime of the battery (12).
US08368337B2 HVAC equipment phase and voltage monitor and control
An HVAC unit includes a transformer and a system controller. The transformer is configured to receive power from a first and a second phase of a three-phase power source and to produce a first reduced-voltage waveform therefrom. The system controller is adapted to sample the reduced voltage waveform to determine a figure of merit of the three-phase power source. The controller is further configured to operate the HVAC unit in response to the figure of merit.
US08368331B2 Methods and apparatus for monitoring average current and input power in an electronically commutated motor
A method for monitoring input power to an electronically commutated motor (ECM) is described. The method includes determining, with a processing device, an average input current to the motor, the average input current based on a voltage drop across a shunt resistor in series with the motor, measuring an average input voltage applied to the motor utilizing the processing device, multiplying the average input current by the average voltage to determine an approximate input power, and communicating the average input power to an external interface.
US08368327B2 System and method for maintaining performance of battery-operated toothbrushes
The system periodically measures the battery voltage of the toothbrush and the current in a stator portion of the motor for the appliance. The amplitude of movement of the toothbrush workpiece is determined from the measured stator current. A circuit/control program changes the duty cycle or pulse width of the drive signal from the motor if the battery voltage drops below a first threshold value and a circuit or control program changes the drive frequency of the appliance if the amplitude of the workpiece movement falls below a first threshold value. A circuit/control program terminates the operation of the toothbrush if the voltage drops below a second threshold value or if the amplitude drops below a second threshold value, both of which are less than the respective first thresholds.
US08368325B2 Lighting system
A lighting system includes a plurality of lights connected to a bridge, a gateway, a lighting controller, and an interface. A plurality of commands to control a corresponding light may be stored in a memory. A communication module may be provided to generate a packet for transmission to the gateway based on the plurality of stored commands. The packet may combine a plurality of the commands for controlling one or more of the lights.
US08368324B2 Driving apparatus and method for adjusting drive voltage
A driving apparatus includes a voltage transforming unit and a detector. The driving apparatus is used for supplying a drive voltage to a load. The voltage transforming unit is used for transforming a direct current (DC) voltage to the drive voltage. The detector is connected to the load for detecting a forward voltage across the load to generate a detecting voltage; wherein the detector compares the detecting voltage with a first reference voltage. If the detecting voltage is smaller than the first reference voltage, the detector generates a first feedback signal; the voltage transforming unit increases the drive voltage according to the first feedback signal, the detecting voltage is defined by subtraction of the forward voltage from the drive voltage.
US08368323B2 Power supply unit having dimmer function and lighting unit
In a power supply unit, if a dimmer rate is changed within a range of k1, k2, . . . k7 by a dimmer signal k of a dimmer signal generator, light-emitting diodes are controlled to be lighted by a constant current characteristic in an area where the dimmer rate is small according to a load characteristic corresponding to the dimmer rates k1, k2, . . . k7. As the dimmer rate becomes larger, a tendency of a constant voltage characteristic is gradually strengthened from a constant current characteristic so that the light-emitting diodes are lighted at the larger dimmer rate.
US08368321B2 Power management unit with rules-based power consumption management
In embodiments of the present invention, a method and system is provided for designing improved intelligent, LED-based lighting systems. The LED based lighting systems may include fixtures with one or more of rotatable LED light bars, integrated sensors, onboard intelligence to receive signals from the LED light bars and control the LED light bars, and a mesh network connectivity to other fixtures.
US08368320B2 Cold cathode fluorescent lamp driving circuits and associated methods of control
Methods and circuits for CCFL driving circuit control are disclosed according to various embodiments of the present disclosure. In certain embodiments, the methods and circuits for CCFL driving circuit control provide a control signal for regulating both the duty ratio and frequency of the switching control signal that controls the CCFL driving circuit. External components for control loop compensation and frequency sweeping rate, and/or striking frequency setting may also be utilized.
US08368318B2 Pocket tool with a light pointer
The invention relates to a compact light module (1), that is eye-safe as far as possible, comprising an electrical power source (2), a voltage converter (3) and a radiation source for electromagnetic radiation (4), wherein a power limiter (5) is provided for controlling the emitted electromagnetic radiation. The invention also relates to a pocket tool, in particular a pocket knife (26) or board-like tool card (31) with a light module (32) for emitting electromagnetic radiation which is arranged in the housing (27) and can be operated by means of an activating element (30), whereby the light module (32) is designed to emit monochromatic electromagnetic radiation with limited radiation output.
US08368313B2 Electronic candle and electronic night lamp
The invention relates to an electronic candle and an electronic night lamp. The electronic candle includes a light-emitting diode (LED), a capacitor and a control circuit. The capacitor has a first terminal coupled to a first terminal of the LED, and a second terminal coupled to a common voltage. The control circuit has a first control terminal coupled to the first terminal of the LED, and a second control terminal coupled to a second terminal of the LED. In a detecting period, the control circuit provides a preset voltage across the first and second terminals of the LED so that the LED is reversely biased for a preset time. Then, the first control terminal of the control circuit is set to high impedance. Next, the control circuit detects a variation of a voltage of the first terminal of the capacitor with respect to time to determine whether to light up the LED.
US08368312B2 Circuit and method of driving light emitting diodes, and light emitting diode system having the same
A light-emitting-diode driving circuit includes a current driving circuit configured to control current signals flowing through light-emitting-diode strings in response to a first signal that includes information of a light-emitting-diode current, a dynamic headroom controller configured to generate a third control signal that changes according to a change of the current signals flowing through the light-emitting-diode strings based on voltage signals of first terminals of each of the light-emitting-diode strings and a second control signal that includes the information of the light-emitting-diode current, and a power supply circuit configured to generate a light-emitting-diode driving voltage that changes in response to the third control signal, and provide the light-emitting-diode driving voltage to second terminals of each of the light-emitting-diode strings.
US08368311B2 Organic electroluminescent display device
The present invention overcomes image defects such as the brightness inclination or smears by reducing the line resistance of a power source bus line which supplies electricity to organic EL elements. A plurality of pixels which are arranged in a matrix array is connected to power source lines, and the plurality of power source lines are connected to a power source bus line. Both ends of the power source bus line are connected to a power source part via a FPC. By supplying electricity to both ends of the power source bus line from the power source part, the line resistance of the power source bus line can be reduced.
US08368308B2 Inductively coupled plasma reactor having RF phase control and methods of use thereof
Embodiments of the present invention generally provide an inductively coupled plasma (ICP) reactor having a substrate RF bias that is capable of control of the RF phase difference between the ICP source (a first RF source) and the substrate bias (a second RF source) for plasma processing reactors used in the semiconductor industry. Control of the RF phase difference provides a powerful knob for fine process tuning. For example, control of the RF phase difference may be used to control one or more of average etch rate, etch rate uniformity, etch rate skew, critical dimension (CD) uniformity, and CD skew, CD range, self DC bias control, and chamber matching.
US08368306B2 Short arc dimmable HID lamp with constant colour during dimming
The present disclosure relates to a short arc metal halide lamp without outer jacket, whose arc tube has a specified aspect ratio and chemical filling, characterized in that it delivers a low color temperature and very high color rendering index, which are maintained during dimming.
US08368305B2 Rotating wheel electrode device for gas discharge sources comprising wheel cover for high power operation
The present invention relates to an electrode device (1, 2) for gas discharge sources and to a gas discharge source having one or two of said electrode devices (1, 2). With the proposed design of the cover (8), an efficient cooling of the electrode wheel (7) is achieved, allowing high electrical powers for operating gas discharge sources with such an electrode device.
US08368304B2 Discharge lamp
In various embodiments, a discharge lamp may include a lamp vessel that includes a discharge vessel enclosing a discharge medium and two lamp shafts each extending coaxially at opposite ends of the discharge vessel, two outer power-feed sections each extending to the outside from one of the lamp shafts, two electrodes each consisting of an electrode rod and electrode head, with the electrode rods being arranged along the lamp shafts such that the two electrode heads are located mutually opposite inside the discharge vessel, a sealed section in each of the two lamp shafts by which a gas-tight electricity passage is formed between the two outer power-feed sections on the one hand and the two electrodes on the other, a narrow section in each of the two lamp shafts that is arranged between the respective sealed section and the electrode head of the associated electrode, with the narrow section closely surrounding the electrode rod, and a damping/guiding element arranged between the narrow section of a lamp shaft and the electrode rod of at least one electrode.
US08368302B2 Flat panel display device having reduced FRIT delamination and method of fabricating the same
A flat panel display device and a method of fabricating the same, the flat panel display device including: a first substrate including a display portion to display an image and a peripheral portion disposed outside the display portion; a second substrate facing the first substrate; a frit disposed on the peripheral portion, to attach the first substrate to the second substrate; and a signal interconnection having portions overlapping the frit, to transmit a signal to the display portion. Edges of the signal interconnection that are overlapped by the frit are patterned, to prevent delamination of the frit.
US08368300B2 Light emitting device, light emitting device package, and lighting system
Provided are a light emitting device, a light emitting device package, and a lighting system. The light emitting device includes a substrate, a light emitting structure on the substrate, the light emitting structure comprising a first conductive type semiconductor layer, a second conductive type semiconductor layer on the first conductive type semiconductor layer, and an active layer between the first and second conductive type semiconductor layers; a first electrode on the light emitting structure; and a patterned phosphor layer on the light emitting structure, wherein the patterned phosphor layer converts light generated from the light emitting structure into light having a wavelength longer than that of the light generated from the light emitting structure, and wherein the pattern of the phosphor layer exposes the first electrode.
US08368299B2 Organic light emitting diode display
An organic light emitting diode (OLED) display including a substrate, a thin film transistor (TFT) formed on the substrate, an OLED, a colored polarizing member on the OLED, and a colored material on the OLED and having a color that is different from that of the polarizing member. The OLED includes a pixel electrode, an organic emission layer on the pixel electrode, and a common electrode on the organic emission layer, wherein the pixel electrode is coupled to the TFT.
US08368298B2 Display device with multiple OLEDS
To improve an image quality of an organic EL display by utilizing characteristics of a dual emission type organic light emitting element. A display device includes a first substrate over which a plurality of organic light emitting elements are provided and a second substrate over which an organic light emitting element is provided. The first and second substrates are facing each other. At least either the organic light emitting elements provided over the first substrate or the organic light emitting element provided over the second substrate emit/emits light toward both surfaces of the first or second substrate. Light emitting regions of the organic light emitting elements provided over the first substrate are overlapped with a light emitting region of the organic light emitting element provided over the second substrate as seen from the second substrate.
US08368292B2 Glare-free LED lamp module
A glare-free light emitting diode (LED) lamp module includes a heat sink, an LED light source and an LED cover. Multiple rows of threads are integrally formed on a circumferential outer surface of the heat sink for the purposes of mounting and heat dissipation. In one embodiment, a mounting portion is provided on and integrally formed with the heat sink. The LED light source is mounted on the mounting portion. The LED cover is attached to the mounting portion. In another embodiment, a mounting hole is defined through the heat sink for receiving and mounting an LED lamp core and an LED lamp socket therein. The LED cover is attached to the LED lamp core. The LED lamp module can be used to replace the bulb of an incandescent lamp, while the other parts of the incandescent lamp can be retained for continuing use.
US08368290B2 Rectifier-free piezoelectric energy harverster and battery charger
A circuit for harvesting electrical energy from a piezoelectric source and for storing the electrical energy in a battery includes an inductor that is configured to store electrical energy. A diode bridge-free switching network is configured to: direct electrical energy from the piezoelectric source to the inductor during a first portion of a piezoelectric charge generating cycle; and direct electrical energy from the inductor to the battery during a second portion of the piezoelectric charge generating cycle.
US08368285B2 Electrochemical actuators
Devices and methods for providing electrochemical actuation are described herein. In one embodiment, an actuator device includes an electrochemical cell including a negative electrode and a positive electrode At least a portion of the negative electrode is formed with a material formulated to at least one of intercalate, de-intercalate, alloy with, oxidize, reduce, or plate with a first portion of the positive electrode to an extent different than with a second portion of the positive electrode such that a differential strain is imparted between the first portion and the second portion of the positive electrode and such that at least a portion of the electrochemical cell is displaced. The electrochemical cell includes a portion that is pre-bent along an axis of the electrochemical cell to define a fold axis and the displacement of the at least a portion of the electrochemical cell is maximized along the fold axis.
US08368282B2 Disk drive device rotationally driving recording disk
A disk drive device includes: a hub on which a recording disk is to be mounted; a base configured to rotatably support the hub via a bearing; a core that is fixed to the base and includes a circular portion and S salient poles (where S is a natural number greater than or equal to 3) extending from the circular portion in the diameter direction; a three-phase coil that is formed by being wound around each of the S salient poles; and a magnet that is fixed to the hub and faces the S salient poles in the diameter direction, and that is provided with P driving magnetic poles in the circumferential direction (where P is a natural number greater than or equal to 2). In the disk drive device, the fundamental frequency component of the cogging torque based on the LCM (Least Common Multiple) of S and P (where S is the number of the salient poles of the core and P is the number of the driving magnetic poles of the magnet), is smaller than the second frequency component of the cogging torque, the frequency of which is twice the fundamental frequency.
US08368279B2 Commutator for an electrical machine, and electrical machine
The invention relates to a commutator for an electrical machine, having a commutator body on the outer circumference of which a plurality of electrically conductive, elongated laminations are disposed parallel to the longitudinal axis of the commutator. The laminations disposed adjacent to one another are electrically insulated from one another. The ends of the laminations, oriented toward the wire windings of an armature, are each electrically conductively connected to at least one wire end. According to the invention, it is provided that the ends of the laminations end, perpendicular to the longitudinal axis of the commutator, in planes offset from one another.
US08368268B2 Optical-device switching apparatus for microscope
An optical-device switching apparatus of a microscope includes a driving motor, and a rotation unit that is rotatably attached to a body and to which optical devices are attached, and a gear apparatus that is located between the driving motor and the rotation unit and transmits power from the driving motor to the rotation unit. The gear apparatus includes a backlash reduction system that reduces backlash.
US08368264B2 Electric cutting tool
An electric cutting tool including a housing (1) and a motor (2). The motor (2) is removably mounted in a cavity arranged at the back end of the housing (2), and the outer diameter of the motor (2) is matched with the diameter of the cavity. A turnover opening back cover (3) is hinged at the opening at the back end of the cavity. The back cover (3) is locked with the housing (1) by means of a locking structure arranged on its side, and presses against the back end of the motor (2) after closing. A pair of electrode posts (21) are provided at the front end of the motor (2), and a pair of electrode sockets (18) corresponding one-to-one with the pair of electrode posts (21) are provided in the bottom surface of the cavity. A circumferential stop structure is provided between the radial outer surface of the motor (2) and the inner wall of the cavity. The motor (2) is circumferentially fastened by the circumferential stop structure, causing the polarities of the electrode posts (21) and those of the electrode sockets (18) matching.
US08368260B2 Instantaneous magnetodynamic generator
An instantaneous magnetodynamic generator includes a magnetic plate and a first metallic electrode plate. The magnetic plate has at least one pair of N and S magnetic poles. One magnetic pole of the pair of N and S magnetic poles has a first magnetic pole face, and the other magnetic pole of the pair of N and S magnetic poles has a second magnetic pole face. The first metallic electrode plate has an electrode face and at least one metallic wire. The electrode face faces the first and second magnetic pole faces. The metallic wire has a free end moving between a position beneath the first magnetic pole face and a position beneath the second magnetic pole face to induce a positive or negative tunneling current on the first metallic electrode plate.
US08368259B2 Linear motor component mounting apparatus and component inspecting apparatus
The invention relates to a linear motor equipped with a field element and an armature and adapted to produce a force causing the field element and the armature to be relatively displaced along a given axial direction by interaction of magnetic fluxes generated between the field element and the armature during an operation of supplying electric power to the armature. In one typical aspect of the invention, the linear motor is provided with: a stator which is formed as one of the field element and the armature; a mover which is formed as the other of the field element and the armature; a frame member which defines the axial direction; a rail which is adapted to guide the mover allowing only to reciprocate in a linear direction; a first positioning portion which is provided on the frame member to set a fixing position of the stator with respect to the frame member; and a second positioning portion which is provided on the frame member to set a fixing position of the rail with respect to the frame member in such a manner as to allow the mover to reciprocate along the axial direction with a given gap formed between the mover and the stator positioned by the first positioning portion.
US08368255B2 Voice coil motor
A VCM is disclosed, the VCM including a bobbin formed with a coil at an outer surface thereof; at least one permanent magnet facing the coil formed at the bobbin; a cylindrical yoke encompassing the bobbin and the permanent magnet and including a metal member for blocking a magnetic field generated by the coil; a base coupled to the yoke; and an elastic member including a first elastic member interposed between the yoke and the permanent magnet for elastically supporting the bobbin and a second elastic member interposed between the base and the permanent magnet.
US08368252B2 High- and low-power power supply with standby power saving features
A power supply for providing power to an electrical device is described. The power supply converts a received input signal to a first electrical having a first voltage level at a first power converter. The power supply additionally converts the first electrical signal to a second electrical signal having a second voltage level at a second power converter, to provide the second electrical signal having the second voltage level to an output port. The power supply includes a circuit to selectively bypass the second power converter and provide the first electrical signal having the first voltage level from the first power converter to the output port. The first power converter may include one or more switches that may be disabled to disconnect power from the first power converter for additional standby power saving features.
US08368250B1 Systems and methods for swapping span power modules in telecommunication networks
The present disclosure generally pertains to systems and methods for swapping span power modules that are used for supplying power to network interface units (NIUs). A span power module in accordance with one exemplary embodiment of the present disclosure has logic capable of communicating with logic of another span power module. When one module is to be swapped for the other module, the module being swapped-in is configured to automatically disable the other module shortly after it has powered up and is supplying electrical power across a span line. The amount of time that both modules supply power to the span line is sufficiently small such that damage to electrical communication equipment receiving power from the span line is prevented.
US08368245B2 Out-door unit with multiple ports
An out-door unit with multiple ports comprises a circuit block, a DC-DC converter and a plurality of ports. The DC-DC converter is configured to provide a first current to the circuit block. The plurality of ports is connected to a plurality of in-door units respectively via a diode and provides a second current from the plurality of in-door units to the DC-DC converter via a diode respectively. The circuit block requires an operation current, and a first part of the operation current is the first current from the DC-DC converter and a second part of the operation current is the second current from one of the ports.
US08368243B1 Roofline conduit for wind generator
A wind generator assembly for driving an electric generator having an inlet air riser having an upper end disposed to capture portions of roof level wind currents and a lower end. The lower end of the inlet air riser extends upward from and is in communication with an air box that houses a rotator assembly. An air inlet turret is mounted for rotation by roof currents to be directed to gather and pass a portion of the roof currents into the inlet air riser. The rotator assembly has a rotor supported on a support arbor that is rotated in a predetermined rotational direction by roof level wind currents. The support arbor is connectable to an electric power generator.
US08368241B2 Wind driven power generator
A power generator using a floating object and exhibiting further improved power generation efficiency includes a floating object including a floating body arranged to catch wind, a plurality of posture control strings, and a posture control instrument, at least one first control string connected to the posture control instrument, a first control string take-in device arranged to take the at least one first control string into a first base body, a forward/backward movement control device arranged to control forward/backward movements of the posture control strings, a first winding device arranged to wind a proximal send of the at least one first control string, a second control string connected to the posture control instrument, a second control string take-in device arranged to take the second control string into a second base body installed apart from the first base body, and a second winding device around which a proximal end of the second control string is wound. The at least one first control string or the posture control instrument that mounts a communication device is arranged to control a front/rear inclination angle θ of the floating object, and the second control string is reeled out/taken up in accordance with the front/rear inclination to generate electric power.
US08368240B1 Roof installed wind turbine vent and solar panel electric power generation system
Systems and methods for generating electrical electricity use a wind turbine vent and an electrical generator operably coupled to the wind turbine for generating electricity from spinning of said wind turbine. An air flow guiding device extends between the wind turbine and a fan for guiding fan generated moving air between the wind turbine and fan. One or more solar panels for powering said fan are provided. When the system is installed on a building, the wind turbine turns as a result of outside wind, hot rising air escaping outside through the wind turbine vent, moving air generated by the fan powered by the solar panel, or a combination thereof, and thereby generates electricity. A solar battery can also be used for powering the fan. The system can be used to cool or heat the building while generating electricity.
US08368234B2 Semiconductor device, production method for the same, and substrate
A semiconductor device is provided in which a semiconductor chip is bonded to a substrate with a sufficiently increased bonding strength and cracking is assuredly prevented which may otherwise occur due to heat shock, heat cycle and the like. The semiconductor device includes a semiconductor chip and a substrate having a bonding area to which the semiconductor chip is bonded via a metal layer. The metal layer includes an Au—Sn—Ni alloy layer and a solder layer provided on the Au—Sn—Ni alloy layer. Undulations are formed in an interface between the Au—Sn—Ni alloy layer and the solder layer.
US08368232B2 Sacrificial material to facilitate thin die attach
A sacrificial material applied to a thin die prior to die attach provides stability to the thin die and inhibits warpage of the thin die as heat is applied to the die and substrate during die attach. The sacrificial material may be a material that sublimates at a temperature near the reflow temperature of interconnects on the thin die. A die attach process deposits the sacrificial material on the die, attaches the die to a substrate, and applies a first temperature to reflow the interconnects. At the first temperature, the sacrificial material maintains substantially the same thickness. A second temperature is applied to sublimate the sacrificial material leaving a clean surface for the later packaging processes. Examples of the sacrificial material include polypropylene carbonate and polyethylene carbonate.
US08368228B2 Area efficient through-hole connections
Using developed photo-resist materials as insulator materials for through-hole connections, the preferred embodiments of the present invention improve the area efficiency of electrical devices manufactured on silicon substrates. The area efficiency is further improved by opening holes from both sides of silicon substrate to form through-holes. Besides area efficiency, these methods also provide better control in parasitic impedance of through-hole connection.
US08368227B2 Semiconductor element and package having semiconductor element
The present disclosure relates to a semiconductor process, a semiconductor element and a package having a semiconductor element. The semiconductor element includes a base material and at least one through via structure. The base material has a first surface, a second surface, at least one groove and at least one foundation. The groove opens at the first surface, and the foundation is disposed on the first surface. The through via structure is disposed in the groove of the base material, and protrudes from the first surface of the base material. The foundation surrounds the through via structure. Whereby, the foundation increases the strength of the through via structure, and prevents the through via structure from cracking.
US08368224B2 Under land routing
An electronic component comprising an integrated device and a plurality of packaging layers in which routing between locations on the device and lands on the surface of the component is provided by a redistribution layer. The redistribution layer may be routed below the extent of a contact pad on the surface by providing a channel through the via and redistribution layers underneath that land.
US08368223B2 Paste for forming an interconnect and interconnect formed from the paste
A paste for forming an interconnect includes a mixture of binder particles, filler particles and flux material, binder particles having a melting temperature that is lower than that of the filler particles, and the proportion of the binder particles and the filler particles being selected such when heat is applied to melt the binder particles the shape of the paste as deposited is substantially retained thereby allowing for the paste to be used for forming interconnect structures.
US08368222B2 Semiconductor device with pad with less diffusible contacting surface and method for production of the semiconductor device
A semiconductor device with a connection pad in a substrate, the connection pad having an exposed surface made of a metallic material that diffuses less readily into a dielectric layer than does a metal of a wiring layer connected thereto.
US08368221B2 Hybrid contact structure with low aspect ratio contacts in a semiconductor device
By forming the first metallization layer of a semiconductor device as a dual damascene structure, the contact elements may be formed on the basis of a significantly reduced aspect ratio, thereby enhancing process robustness and also improving electrical performance of the contact structure.
US08368219B2 Buried silicide local interconnect with sidewall spacers and method for making the same
A buried local interconnect and method of forming the same counterdopes a region of a doped substrate to form a counterdoped isolation region. A hardmask is formed and patterned on the doped substrate, with a recess being etched through the patterned hardmask into the counterdoped region. Dielectric spacers are formed on the sidewalls of the recess, with a portion of the bottom of the recess being exposed. A metal is then deposited in the recess and reacted to form silicide at the bottom of the recess. The recess is filled with fill material, which is polished. The hardmask is then removed to form a silicide buried local interconnect.
US08368218B2 Adhesive flexible barrier film, method of forming same, and organic electronic device including same
An adhesive flexible barrier film comprises a substrate and a barrier layer disposed on the substrate. The barrier layer is formed from a barrier composition comprising an organosilicon compound. The adhesive flexible barrier film also comprises an adhesive layer disposed on the barrier layer and formed from an adhesive composition. A method of forming the adhesive flexible barrier film comprises the steps of disposing the barrier composition on the substrate to form the barrier layer, disposing the adhesive composition on the barrier layer to form the adhesive layer, and curing the barrier layer and the adhesive layer. The adhesive flexible barrier film may be utilized in organic electronic devices.
US08368210B2 Wafer scale package for high power devices
A semiconductor device package is formed of DBC in which thinned MOSgated and/or diode die are soldered to the bottom of an etched depression in the upper conductive layer. A via in the insulation layer of the DBC is filled with a conductive material to form a resistive shunt. Plural packages may be formed in a DBC card and may be separated individually or in clusters. The individual packages are mounted in various arrays on a support DBC board and heat sink. Integrated circuits may be mounted on the assembly and connected to the die for control of the die conduction.
US08368206B2 Heat radiation package and semiconductor device
A heat radiation package of the present invention includes a substrate in an upper surface side of which recess portion is provided, embedded wiring portion which is filled in the recess portion of the substrate and on which semiconductor element which generates a heat is mounted, and a heat sink connected to a lower surface side of the substrate. The substrate is made of silicon, ceramics, or insulating resin.
US08368205B2 Metallic thermal joint for high power density chips
A method for the assembly of a semiconductor package that includes cleaning a surface of a chip and a surface of a heat removal device by reverse sputtering is given. The method includes sequentially coating the surface of the chip and the surface of the heat removal device with an adhesive layer, a barrier layer, and a protective layer over a target joining area. The chip and the heat removal device are placed into carrier fixtures and preheated to a target temperature. Then a metallic thermal interface material (TIM) preform is mechanically rolled onto the surface of the chip and the first and the second carrier fixtures are attached together such that the metallic TIM layer on the surface of the chip is joined to the coated surface of the heat removal device through a fluxless process. The method includes heating the joined carrier fixtures in a reflow oven.
US08368203B2 Heat radiation member for a semiconductor package with a power element and a control circuit
A semiconductor package includes a metal plate, a power element, a lead frame having a die pad, a resin sheet having insulation properties, a control circuit that controls the power element, and a mold resin. The power element is mounted on the die pad, and the die pad is mounted on the metal plate via the resin sheet. The resin sheet is expanded including at least a lower surface of the die pad while the lower surface of the resin sheet is smaller than an surface of the metal plate, and the control circuit is arranged in a region on the metal plate, which region is other than the region where the power element is arranged.
US08368200B2 Shielded stacked integrated circuit packaging system and method of manufacture thereof
A method of manufacture of a shielded stacked integrated circuit packaging system includes: forming a first integrated circuit structure having a first substrate and a first integrated circuit die; mounting a shield over the first substrate and the first integrated circuit die; mounting a second integrated circuit structure having a second substrate and a second integrated circuit die over the shield; and forming a package encapsulation for covering the first integrated circuit die, the shield, and the second integrated circuit structure.
US08368199B2 Integrated circuit package system for stackable devices and method for manufacturing thereof
A method for manufacturing an integrated circuit package system includes: forming a stack module including: providing a stack die and encapsulating the stack die with an insulating material having a protruding support and a pad connected to the stack die; mounting the stack module on a package base; connecting the pad to the package base; mounting a top die on the protruding support; connecting the top die to the package base; and encapsulating the top die, the package base, and the stack module with a package encapsulant.
US08368196B2 Micro device having a movable structure
The micro device includes a support substrate, and a movable structure configured to move with respect to the support substrate. At least one of the support substrate and the movable structure is provided with at least one protrusion protruding towards the other of the support substrate and the movable structure. Further, a base portion extending into the one of the support substrate and the movable structure is provided integrally with the at least one protrusion. With this configuration, the protrusion is securely held by the base portion, and the detachment of the protrusion can therefore be prevented even after repeated collisions between the support substrate and the movable structure via the protrusion.
US08368194B1 Exposed die overmolded flip chip package
An exposed die overmolded flip chip package includes a substrate. A die is flip chip mounted to an upper surface of the substrate. The package further includes a mold cap filling a space between an active surface of the die and the upper surface of the substrate. The mold cap includes a principal surface, sidewalls extending from the upper surface of the substrate to the principal surface, an annular surface coplanar with the inactive surface of the die and extending outward from a peripheral edge of the inactive surface of the die, and protruding surfaces extending between the principal surface and the annular surface. The mold cap does not cover the inactive surface of the die such that heat transfer from the die to the ambient environment is maximized and the package thickness is minimized.
US08368190B2 LED package having an array of light emitting cells coupled in series
Disclosed is a light emitting diode (LED) package having an array of light emitting cells coupled in series. The LED package comprises a package body and an LED chip mounted on the package body. The LED chip has an array of light emitting cells coupled in series. Since the LED chip having the array of light emitting cells coupled in series is mounted on the LED package, it can be driven directly using an AC power source.
US08368188B2 Drop-mold conformable material as an encapsulation for an integrated circuit package system and method for manufacturing thereof
A method for manufacturing an integrated circuit package system includes: providing an integrated circuit; mounting a lead on the periphery of the integrated circuit; connecting the integrated circuit to the lead with an interconnect; and forming a conformable material by pressing the conformable material on the integrated circuit, the lead, and the interconnect.
US08368180B2 Scribe line metal structure
A system and method for preventing defaults during singulation is presented. An embodiment comprises a dummy metal structure located in the scribe region. The dummy metal structure comprises a series of alternating dummy lines that are connected through dummy vias. The dummy lines are offset from dummy lines in adjacent metal layers. Additionally, the dummy lines and dummy vias in the upper layers of the scribe line may be formed with larger dimensions than the dummy lines and dummy vias located in the lower layers.
US08368179B2 Miscut semipolar optoelectronic device
A method for improved growth of a semipolar (Al,In,Ga,B)N semiconductor thin film using an intentionally miscut substrate. Specifically, the method comprises intentionally miscutting a substrate, loading a substrate into a reactor, heating the substrate under a flow of nitrogen and/or hydrogen and/or ammonia, depositing an InxGa1-xN nucleation layer on the heated substrate, depositing a semipolar nitride semiconductor thin film on the InxGa1-xN nucleation layer, and cooling the substrate under a nitrogen overpressure.
US08368178B2 Phase change memory apparatus and fabrication method thereof
A phase change memory apparatus is provided that includes a first electrode that is longer than it is wide, the first electrode having a trench formed on an active region of a semiconductor substrate, a second electrode formed in a bottom portion of the trench, and a bottom electrode contact formed on the second electrode.
US08368177B2 Integrated circuit with ESD structure
An integrated circuit includes a semiconductor body of a first conductivity type. The semiconductor body includes a first semiconductor zone of a second conductivity type opposite the first conductivity type. The first semiconductor zone extends to a surface of the semiconductor body. A second semiconductor zone of the first conductivity type is embedded in the first semiconductor zone and extends as far as the surface. A third semiconductor zone of the second conductivity type at least partly projects from the first semiconductor zone along a lateral direction running parallel to the surface. A contact structure provides an electrical contact with the first and second semiconductor zones at the surface. The second semiconductor zone is arranged, along the lateral direction, between the part of the third semiconductor zone which projects from the first semiconductor zone and a part of the contact structure in contact with the first semiconductor zone.
US08368173B2 Semiconductor package and method for making the same
The present invention relates to a semiconductor package and a method for making the same. The semiconductor package includes a base material, a first metal layer, a first dielectric layer, a first upper electrode and a first protective layer. The first metal layer is disposed on a first surface of the base material, and includes a first inductor and a first lower electrode. The first dielectric layer is disposed on the first lower electrode. The first upper electrode is disposed on the first dielectric layer, and the first upper electrode, the first dielectric layer and the first lower electrode form a first capacitor. The first protective layer encapsulates the first inductor and the first capacitor. Whereby, the first inductor and the first lower electrode of the first capacitor are disposed on the same layer, so that the thickness of the product is reduced.
US08368167B1 Schottky diode with extended forward current capability
The embodiments of the present invention disclose a semiconductor device and a method for forming the semiconductor device. Wherein the semiconductor comprises: a first semiconductor layer, having a first conductivity type on a semiconductor substrate, a guard ring region, formed in the surface of the first semiconductor layer, having a second conductivity type; a Schottky diode metal contact, coupled to the first semiconductor layer, wherein the guard ring region is at periphery of the Schottky diode interface, and wherein the Schottky diode metal contact has no direct electrical connection with the guard ring region; and an electrical resistance module, coupled between the Schottky diode metal contact and the guard ring. Due to the ballasting effect from the electrical resistance module, the minority injection or the parasitic transistor action are alleviated. Thus, forward current capability is extended without introducing significant minority injection.
US08368165B2 Silicon carbide Schottky diode
A SiC Schottky diode which includes a Schottky barrier formed on a silicon face 4H—SiC body.
US08368160B2 Image sensing device and fabrication thereof
An image sensing device is disclosed, including an epitaxy layer having the a conductivity type, including a first pixel area corresponding to a first incident light, a second pixel area corresponding to a second incident light, and a third pixel area corresponding to a third incident light, wherein the wavelength of the first incident light is longer than that of the second incident light and the wavelength of the second incident light is longer than that of the third incident light. A photodiode is disposed in an upper portion of the epitaxy layer, and a first deep well for reducing pixel-to-pixel talk of the image sensing device is disposed in a lower portion of the epitaxy layer in the second pixel area and the third pixel area, wherein at least a portion of the epitaxy layer in first pixel area does not include the first deep well.
US08368159B2 Photon counting UV-APD
An avalanche photodiode (APD) has a first semiconductor substrate having a first doping type. A first semiconductor layer is on top of the first semiconductor substrate. The first semiconductor layer is doped with the first doping type. A second epitaxial layer is on top of the first semiconductor layer. The second epitaxial layer is in-situ doped with the first doping type at a concentration higher than a concentration of the first doping type in the first semiconductor layer. A third epitaxial layer is on top of the second epitaxial layer. The third epitaxial layer is in-situ doped with a second doping type. The doping of the third epitaxial region forms a first p-n junction with the doping of the second epitaxial layer, wherein a carrier multiplication region includes the first p-n junction, and wherein the third epitaxial layer forms an absorption region for photons. A first implanted region is within the third epitaxial layer. The implanted region is doped with the second doping type.
US08368157B2 Backside illumination image sensors with reflective light guides
Image sensors with backside illumination image pixel arrays are provided. An image pixel array may have image pixels that are formed on a silicon substrate having front and back surfaces. The pixel array may have photodiodes formed in the front surface. A dielectric stack may be formed on the front surface. The dielectric stack may include interconnect structures and reflective light guides. A color filter array may be formed on the back surface of the substrate. Microlenses may be formed on the color filter array from the side facing the back surface. The pixel array may receive incoming light through the microlenses. The incoming light may enter the substrate through the back surface. The incoming light may penetrate the substrate and may be reflected by a light reflector in the reflective light guide back towards the photodiode. The image pixel array may exhibit improved quantum efficiency, sensitivity, and image contrast.
US08368155B2 Systems and methods for preparing freestanding films using laser-assisted chemical etch, and freestanding films formed using same
Systems and methods for preparing freestanding films using laser-assisted chemical etch (LACE), and freestanding films formed using same, are provided. In accordance with one aspect a substrate has a surface and a portion defining an isotropically defined cavity; and a substantially continuous film is disposed at the substrate surface and spans the isotropically defined cavity. In accordance with another aspect, a substrate has a surface and a portion defining an isotropically defined cavity; and a film is disposed at the substrate surface and spans the isotropically defined cavity, the film including at least one of hafnium oxide (HfO2), diamond-like carbon, graphene, and silicon carbide (SiC) of a predetermined phase. In accordance with still another aspect, a substrate has a surface and a portion defining an isotropically defined cavity; and a multi-layer film is disposed at the substrate surface and spans the isotropically defined cavity.
US08368152B2 MEMS device etch stop
The present disclosure provides a micro-electro-mechanical systems (MEMS) device and a method for fabricating such a device. In an embodiment, a MEMS device includes a substrate, a dielectric layer above the substrate, an etch stop layer above the dielectric layer, and two anchor plugs above the dielectric layer, the two anchor plugs each contacting the etch stop layer or a top metal layer disposed above the dielectric layer. The device further comprises a MEMS structure layer disposed above a cavity formed between the two anchor plugs and above the etch stop layer from release of a sacrificial layer.
US08368150B2 High performance IC chip having discrete decoupling capacitors attached to its IC surface
In the present invention, discrete decoupling capacitors are mounted on the surface of an IC chip. Since a discrete capacitor can provide the capacitance of the magnitude μF, the attached capacitors can serve as the local power reservoir to decouple the external power ground noise caused by wirebonds, packages, and other system components.
US08368147B2 Strained semiconductor device with recessed channel
A semiconductor device having a strained channel and a method of manufacture thereof is provided. The semiconductor device has a gate electrode formed over a channel recess. A first recess and a second recess formed on opposing sides of the gate electrode are filled with a stress-inducing material. The stress-inducing material extends into an area wherein source/drain extensions overlap an edge of the gate electrode. In an embodiment, sidewalls of the channel recess and/or the first and second recesses may be along {111} facet planes.
US08368142B2 Semiconductor device and method of manufacturing the same
A semiconductor device having performance comparable with a MOSFET is provided. An active layer of the semiconductor device is formed by a crystalline silicon film crystallized by using a metal element for promoting crystallization, and further by carrying out a heat treatment in an atmosphere containing a halogen element to carry out gettering of the metal element. The active layer after this process is constituted by an aggregation of a plurality of needle-shaped or column-shaped crystals. A semiconductor device manufactured by using this crystalline structure has extremely high performance.
US08368139B2 Semiconductor device comprising transistor structures and methods for forming same
A method for forming an opening within a semiconductor material comprises forming a neck portion, a rounded portion below the neck portion and, in some embodiments, a protruding portion below the rounded portion. This opening may be filled with a conductor, a dielectric, or both. Embodiments to form a transistor gate, shallow trench isolation, and an isolation material separating a transistor source and drain are disclosed. Device structures formed by the method are also described.
US08368135B2 Field effect transistor with narrow bandgap source and drain regions and method of fabrication
A transistor having a narrow bandgap semiconductor source/drain region is described. The transistor includes a gate electrode formed on a gate dielectric layer formed on a silicon layer. A pair of source/drain regions are formed on opposite sides of the gate electrode wherein said pair of source/drain regions comprise a narrow bandgap semiconductor film formed in the silicon layer on opposite sides of the gate electrode.
US08368132B2 Ferroelectric memory and manufacturing method thereof
Provided is a ferroelectric memory including a silicon substrate, a transistor formed on the silicon substrate, and a ferroelectric capacitor formed above the transistor. The ferroelectric capacitor includes a lower electrode, a ferroelectric film formed on the lower electrode, an upper electrode formed on the ferroelectric film, and a metal film formed on the upper electrode.
US08368131B2 Light detecting apparatus
A light detecting apparatus is provided with a semiconductor substrate, a first electrode layer, and a second electrode layer. The semiconductor substrate has a first conductivity type first semiconductor region, and a second conductivity type second semiconductor region formed on the first semiconductor region and constituting a photodiode based on a pn junction formed between the first semiconductor region and the second semiconductor region. The first electrode layer is arranged above the second semiconductor region so as to be opposed to the second semiconductor region and is electrically connected to the second semiconductor region. The second electrode layer is arranged above the first electrode layer so as to be opposed to the first electrode layer and forms a capacitance component connected to the photodiode, between the first electrode layer and the second electrode layer.
US08368126B2 Trench metal oxide semiconductor with recessed trench material and remote contacts
Remote contacts to the polysilicon regions of a trench metal oxide semiconductor (MOS) barrier Schottky (TMBS) device, as well as to the polysilicon regions of a MOS field effect transistor (MOSFET) section and of a TMBS section in a monolithically integrated TMBS and MOSFET (SKYFET) device, are employed. The polysilicon is recessed relative to adjacent mesas. Contact of the source metal to the polysilicon regions of the TMBS section is made through an extension of the polysilicon to outside the active region of the TMBS section. This change in the device architecture relieves the need to remove all of the oxides from both the polysilicon and silicon mesa regions of the TMBS section prior to the contact step. As a consequence, encroachment of contact metal into the sidewalls of the trenches in a TMBS device, or in a SKYFET device, is avoided.
US08368120B2 Hybrid semiconductor device having a GaN transistor and a silicon MOSFET
A hybrid device including a silicon based MOSFET operatively connected with a GaN based device.
US08368119B1 Integrated structure with transistors and schottky diodes and process for fabricating the same
A process for fabricating an integrated group III nitride structure comprising high electron mobility transistors (HEMTs) and Schottky diodes, and the resulting structure, are disclosed. Integration of vertical junction Schottky diodes is enabled, and the parasitic capacitance and resistance as well as the physical size of the diode are minimized. A process for fabricating an integrated group III nitride structure comprising double-heterostructure field effect transistors (DHFETs) and Schottky diodes and the resulting structure are also disclosed.
US08368114B2 Flip chip LED die and array thereof
A flip chip LED die is provided and includes a first type doped layer, a second type doped layer, a first electrode layer, a second electrode layer and an insulation layer. The second type doped layer is disposed under the first type doped layer. The first electrode layer is disposed under the first type doped layer without contacting the second type doped layer. The first electrode layer has an exposed area for directly coating an electrically conductive adhesive thereon. The second metal/electrode layer is disposed under the second type doped layer, and also has an exposed area for directly coating the electrically conductive adhesive thereon. The insulation layer is disposed between the first electrode layer and the second electrode layer for electrically insulating and supporting the first electrode layer and the second electrode layer.
US08368111B2 Semiconductor light emitting device and method for manufacturing thereof
Provided is a semiconductor light emitting device and a method for manufacturing the same. The semiconductor light emitting device includes a light emitting structure, an insulating substrate, a first electrode, a second electrode, and a conductive supporting substrate. The light emitting structure includes a first conductive semiconductor layer, an active layer, and a second conductive semiconductor layer. The insulating substrate is formed on the light emitting structure to include a contact groove. The first electrode is formed on the insulating substrate. The second electrode is formed under the light emitting structure. The conductive supporting substrate is formed under the second electrode.
US08368107B2 Light emitting device, method of manufacturing the same, and light emitting device package
A light emitting device according to the embodiment includes a conductive support member having a step portion at an outer peripheral region thereof, a protective member for filling the step portion formed at the outer peripheral region of the conductive support member, a reflective layer over the conductive support member, and a light emitting structure over the reflective layer and the protective member.
US08368102B2 Light emitting device
A light emitting device has a light emitting layer having a first semiconductor layer of a first conductivity type, a second semiconductor layer of a second conductivity type different from the first conductivity type, and an active layer sandwiched between the first semiconductor layer and the second semiconductor layer, a reflecting layer provided on a side of one surface of the light emitting layer, which reflects a light emitted from the active layer, a supporting substrate provided on an opposite side of the reflecting layer with respect to the light emitting layer, which supports the light emitting layer via an adhesion layer, an ohmic contact portion provided on a part of the reflecting layer, which electrically connects between the reflecting layer and the light emitting layer, and convexo-concave portions formed on other surface of the light emitting layer and side surfaces of the light emitting layer, respectively, and an insulating film configured to cover the convexo-concave portions.
US08368099B2 Light emitting device and fabricating method thereof
A light emitting device and a fabricating method thereof are described. The light emitting device includes a substrate, a light emitting chip, a tubular structure, and a fluorescent conversion layer. The tubular structure is formed on a surface of the substrate. The light emitting chip is disposed on the surface of the substrate and is surrounded by the tubular structure. The fluorescent conversion layer is disposed in the tubular structure and covers the light emitting chip. A ratio of a maximal vertical thickness and a maximal horizontal thickness of the fluorescent conversion layer at the light emitting chip is between 0.1 and 10. A distance for the light ray to pass through the fluorescent conversion layer is controlled by using the tubular structure, so as to solve a problem of the conventional art that fluorescent powder coating package technique results in non-uniform color temperature of the emitted light.
US08368098B2 Light emitting device and manufacturing method thereof
The present invention provides a light emitting device loaded with a light emitting semiconductor chip with a protective film formed on a light emitting portion, in which the protective film contains a first dielectric film formed of aluminum oxynitride, a second dielectric film formed of silicon nitride or silicon oxynitride, and a third dielectric film formed of an oxide or a fluoride, the first dielectric film is located more toward the light emitting portion than the second dielectric film, and the second dielectric film is located more toward the light emitting portion than the third dielectric film, and a manufacturing method of the light emitting device.
US08368095B2 Nitride semiconductor light emitting device and method of fabricating nitride semiconductor laser device
There is provided a nitride semiconductor light emitting device having a light emitting portion coated with a coating film, the light emitting portion being formed of a nitride semiconductor, the coating film in contact with the light emitting portion being formed of an oxynitride. There is also provided a method of fabricating a nitride semiconductor laser device having a cavity with a facet coated with a coating film, including the steps of: providing cleavage to form the facet of the cavity; and coating the facet of the cavity with a coating film formed of an oxynitride.
US08368093B2 LED unit
An LED unit includes an LED and a lens mounted on the LED. The lens includes a light-incident face adjacent to the LED, a light-emergent face remote from the LED, and a light-reflecting face between the light-incident face and the light-emergent face. The light-incident face includes a first light-incident face which faces the LED, and the light-emergent face includes a first light-emergent face located opposite to the first light-incident face. The first light-emergent face is a continuously curved face which has a curvature firstly increasing gradually and then decreasing gradually along a bottom-to-top direction of the lens.
US08368091B2 Nanocrystal mixture and light-emitting diode using the same
Disclosed is a light-emitting device. The light-emitting device comprises a blue light-emitting source and a light-emitting source. The light-emitting source includes first semiconductor nanocrystals and second semiconductor nanocrystals. The first and second nanocrystals emit lights of different wavelengths from each other to produce a color complementary to blue. The first and second semiconductor nanocrystals are spatially clustered to form first and second composites respectively.
US08368085B2 Semiconductor package
A semiconductor package includes at least four lead frames each having an extending portion and a connecting portion, a heat dissipation plate having a top surface and a bottom surface, at least one semiconductor chip positioned on the top surface of the heat dissipation plate. At least one conductive wire electrically connects the chip to the lead frames. An encapsulation covers the lead frames, the heat dissipation plate, the semiconductor chip, and the conductive wires, while the bottom surface of the heat dissipation plate and the extending portions of the lead frames are exposed.
US08368084B2 Semiconductor device with capacitor disposed on gate electrode
In an embodiment, provided is a semiconductor device in which a normally-on type FET; a capacitor having one electrode electrically connected to a gate of the FET and the other electrode electrically connected to an input terminal; and a diode having an anode electrode electrically connected to the gate of the FET and a cathode electrode electrically connected to a source of the FET are formed on the same chip on which the FET is formed. Also, the capacitor may have a structure in which an insulation film such as a dielectric substance is formed on a gate drawn electrode of the FET, and a metallic layer is formed on the insulation layer.
US08368083B2 Semiconductor device and manufacturing method of the same
At least part of a semiconductor layer or a semiconductor substrate includes a semiconductor region having a large energy gap. The semiconductor region having a large energy gap is preferably formed from silicon carbide and is provided in a position at least overlapping with a gate electrode provided with an insulating layer between the semiconductor region and the gate electrode. By making a structure in which the semiconductor region is included in a channel formation region, a dielectric breakdown voltage is improved.
US08368082B2 Method for manufacturing semiconductor device, semiconductor device and electronic appliance
A non-single-crystal semiconductor layer is formed over a substrate, and then a single crystal semiconductor layer is formed over part of the non-single-crystal semiconductor layer. Thus, a semiconductor element of a region which requires a large area (e.g. a pixel region in a display device) can be formed using the non-single-crystal semiconductor layer, and a semiconductor element of a region which requires high speed operation (e.g. a driver circuit region in a display device) can be formed using the single crystal semiconductor layer.
US08368077B2 Display device and manufacturing method thereof
A second insulation layer which is formed by stacking a plurality of layers made of different materials in a mutually contact manner is formed such that the second insulation layer covers a source region and a drain region and also covers a gate electrode from above. A first contact hole which reaches one of the source region and the drain region and a recessed portion which is arranged above the gate electrode but is not communicated with the gate electrode are simultaneously formed on the second insulation layer by dry etching. A first line layer is formed so as to cover the first contact hole. After forming the first line layer, a bottom surface of the recessed portion is etched by dry etching thus forming a second contact hole which reaches the gate electrode in the first and second insulation layers. A second line layer is formed on the second contact hole.
US08368068B2 Display with photo sensor and manufacturing method thereof
A display with a photo sensor is provided, wherein the photo sensor is integrated with an active device array substrate of the display and fabricated through an existing process to reduce the manufacturing cost. A photosensitive silicon-rich dielectric layer or any other photosensitive material layer having similar photosensitive characteristics (for example, a photosensitive semiconductor layer) is adopted to form the photo sensor with a lower electrode and a transparent upper electrode. Thereby, the fill factor of the photo sensor is maximized and noises caused by a backlight source electrode are eliminated.
US08368064B2 Glass for scattering layer of organic LED device and organic LED device
A glass to be used in a scattering layer of an organic LED element, and an organic LED element using the scattering layer are provided. The organic LED element of the present invention includes, a transparent substrate, a first electrode provided on the transparent electrode, an organic layer provided on the first electrode, and a second electrode provided on the organic layer, and further includes a scattering layer including, in terms of mol % on the basis of oxides, 15 to 30% of P2O5, 5 to 25% of Bi2O3, 5 to 27% of Nb2O5, and 10 to 35% of ZnO and having a total content of alkali metal oxides including Li2O, Na2O and K2O of 5% by mass or less.
US08368061B2 Organic light-emitting diode employing mixed host and method for fabricating the same
A method for fabricating an organic light-emitting diode employing a mixed host is disclosed, which comprises the following steps: (A) providing a substrate with a first electrode formed thereon; (B) coating a mold with a light-emitting layer material, wherein the light-emitting layer material comprises: a mixed host, and dye molecule(s) (or dye-function-group-composing materials) etc.; (C) pressing the mold coated with the light-emitting layer material onto the substrate to transfer the light-emitting layer material to the first electrode of the substrate, to form a light-emitting layer; and (D) forming a second electrode over the light-emitting layer. The mixed host consists of host-function molecule(s) and auxiliary additives. In addition, the present invention also provides a light-emitting diode, which is prepared by the aforementioned method.
US08368060B2 Light emitting element and light emitting device using the same
An object of the present invention is to provide a light emitting element having slight increase in driving voltage with accumulation of light emitting time. Another object of the invention is to provide a light emitting element having slight increase in resistance value with increase in film thickness. A light emitting element of the invention includes a first layer for generating holes, a second layer for generating electrons and a third layer comprising a light emitting substance between first and second electrodes. The first and third layers are in contact with the first and second electrodes, respectively. The second and third layers are connected to each other so as to inject electrons generated in the second layer into the third layer when applying the voltage to the light emitting element such that a potential of the second electrode is higher than that of the first electrode.
US08368057B2 Organic thin film transistor
An organic thin film transistor includes: a gate electrode, a gate insulating film, a source electrode, a drain electrode, and an organic active layer. The organic active layer includes an organic semiconductor compound represented by the following formula (A) as defined in the specification.
US08368053B2 Multilayer-interconnection first integration scheme for graphene and carbon nanotube transistor based integration
Integrated circuit multilayer integration techniques are provided. In one aspect, a method of fabricating an integrated circuit is provided. The method includes the following steps. A substrate is provided. A plurality of interconnect layers are formed on the substrate arranged in a stack, each interconnect layer comprising one or more metal lines, wherein the metal lines in a given one of the interconnect layers are larger than the metal lines in the interconnect layers, if present, above the given interconnect layer in the stack and wherein the metal lines in the given interconnect layer are smaller than the metal lines in the interconnect layers, if present, below the given interconnect layer in the stack. At least one transistor is formed on a top-most layer of the stack.
US08368052B2 Techniques for forming contacts to quantum well transistors
Techniques are disclosed for providing a low resistance self-aligned contacts to devices formed in a semiconductor heterostructure. The techniques can be used, for example, for forming contacts to the gate, source and drain regions of a quantum well transistor fabricated in III-V and SiGe/Ge material systems. Unlike conventional contact process flows which result in a relatively large space between the source/drain contacts to gate, the resulting source and drain contacts provided by the techniques described herein are self-aligned, in that each contact is aligned to the gate electrode and isolated therefrom via spacer material.
US08368051B2 Complementary barrier infrared detector (CBIRD)
An infrared detector having a hole barrier region adjacent to one side of an absorber region, an electron barrier region adjacent to the other side of the absorber region, and a semiconductor adjacent to the electron barrier.
US08368050B2 Plasmon enhanced light-emitting diodes
Embodiments of the present invention are directed to light-emitting diodes. In one embodiment of the present invention, a light-emitting diode comprises at least one quantum well sandwiched between a first intrinsic semiconductor layer and a second semiconductor layer. An n-type heterostructure is disposed on a surface of the first intrinsic semiconductor layer, and a p-type heterostructure is disposed on a surface of the second intrinsic semiconductor layer opposite the n-type semiconductor heterostructure. The diode also includes a metal structure disposed on a surface of the light-emitting diode. Surface plasmon polaritons formed along the interface between the metal-structure and the light-emitting diode surface extend into the at least one quantum well increasing the spontaneous emission rate of the transverse magnetic field component of electromagnetic radiation emitted from the at least one quantum well. In certain embodiments, the electromagnetic radiation can be modulated at a rate of about 10 Gb/s or faster.
US08368047B2 Semiconductor device
Semiconductor devices including a light emitting layer, and at least one surface plasmon metal layer in contact with the light emitting layer are provided. The light emitting layer includes an active layer having a first band gap, and one or more barrier layers having a second band gap. The first band gap is smaller than the second band gap. Methods for fabricating semiconductor devices are also provided.
US08368046B2 Light-emitting element
A light-emitting element includes a n-type silicon oxide film and a p-type silicon nitride film. The n-type silicon oxide film and the p-type silicon nitride film formed on the n-type silicon oxide film form a p-n junction. The n-type silicon oxide film includes a plurality of quantum dots composed of n-type Si while the p-type silicon nitride film includes a plurality of quantum dots composed of p-type Si. Light emission occurs from the boundary between the n-type silicon oxide film and the p-type silicon nitride film by injecting electrons from the n-type silicon oxide film side and holes from the p-type silicon nitride film side.
US08368042B2 Physical wedge positioning
A method for modulating a radiation beam toward a target, including rotating a radiation beam gantry through an arc segment while irradiating a target with a radiation beam, placing a physical wedge in a beam path of the radiation beam to modify at least one of a beam aperture and a beam intensity of the radiation beam while rotating through the arc segment, and modifying at least one of a wedge angle and a wedge orientation of the physical wedge during a temporal increment associated with the arc segment.
US08368040B2 Radiation system and lithographic apparatus
A radiation system includes a target material supply configured to supply droplets of target material along a trajectory, and a laser system that includes an amplifier and optics. The optics are configured to establish a first beam path which passes through the amplifier and through a first location on the trajectory, and to establish a second beam path which passes through the amplifier and through a second location on the trajectory. The laser system is configured to generate a first pulse of laser radiation when photons emitted from the amplifier are reflected along the first beam path by a droplet of target material at the first location on the trajectory. The laser system is configured to generate a second pulse of laser radiation when photons emitted from the amplifier are reflected along the second beam path by the droplet of target material at the second location on the trajectory.
US08368039B2 EUV light source glint reduction system
An apparatus includes a light source having a gain medium for producing an amplified light beam of a source wavelength along a beam path to irradiate a target material in a chamber and to generate extreme ultraviolet light; and a subsystem overlying at least a portion of an internal surface of the chamber and configured to reduce a flow of light at the source wavelength from the internal surface back along the beam path.
US08368037B2 Systems and methods providing electron beam writing to a medium
A method for electron-beam writing to a medium includes positioning the medium within an e-beam writing machine so that the medium is supported by a stage and is exposed to an e-beam source. The method also includes writing a pattern to the medium using a plurality of independently-controllable beams of the e-beam source, in which the pattern comprises a plurality of parallel strips. Each of the parallel strips is written using multiple ones of the independently-controllable beams.
US08368032B2 Radiation source, lithographic apparatus, and device manufacturing method
A plasma radiation source includes a vessel configured to catch a source material transmitted along a trajectory, and a decelerator configured to reduce a speed of the source material in a section of the trajectory downstream of a plasma initiation site.
US08368028B2 Solid-state image pickup device
A solid-state image pickup device 1 includes a semiconductor substrate 3A having a pixel array 10A with pixels arrayed in M rows and NA columns, a semiconductor substrate 3B having a pixel array 10B with pixels arrayed in M rows and NB columns, and a first column of which is arranged along an NA-th column of the pixel array 10A, and a signal output section 20. The signal output section 20 outputs digital values corresponding to the respective columns from the first column to the n-th column (2≦n
US08368024B2 System and method for attenuation of electrical noise
The Present Invention relates to methods and systems particularly useful in electrical products used to monitor and detect very weak signals. These products include, for example, night vision binoculars and remote listening devices. More specifically, the methods and systems of the Present Invention provide a signal conditioning technique that attenuates electrical noise generated within the product while at the same time preserving the integrity of the input signal. This provides a high signal-to-noise ratio within the product electronics and a dramatically clear final image. The Present Invention includes a method and system for chopping or splitting an input signal into two components, tagging each of the split signal components with opposite polarities, and a second reverse chopping step that combines the split and tagged input signal components into a restored input signal. The combining step, in addition to restoring the original input signal, cancels and attenuates internally generated, and untagged, electronic noise, providing image quality and detection in an efficient and economical manner that could not be obtained in the past.
US08368023B2 Optical bypass device
An optical bypass device comprises a pair of prisms. The capture apertures of the prisms are provided on either side of a projector block. The exit apertures are substantially adjacent to one another. In this manner the prisms can act to direct incident light around the projector block and into the image intensifier aperture. In the projector block is provided an OLED screen operable to display an image including text overlay information corresponding to that captured by the thermal imaging camera. The image is projected through a small opening provided where the prisms are connected.
US08368018B2 Method and apparatus for charged particle beam inspection
A charged particle beam inspection apparatus comprises: an electron gun for irradiating an electron beam onto a sample; a detector for detecting a signal obtained from the sample; an image processor for forming an image from the signal obtained from the detector, and an energy controller for controlling the beam energy of the electron beam to be irradiated onto the sample. An identical charged particle beam inspection apparatus carries out a plurality of types of inspections. An inspection apparatus of a projection type may be applied thereto. A pattern defect inspection, a foreign material inspection, and an inspection for a defect in a multilayer are carried out. Beam energies E1, E2, and E3 in those inspections have a relation E1>E2 and E3>E2. Charge removal is performed in a transport chamber or other vacuum chamber before an inspection.
US08368016B1 Electron beam apparatus and a device manufacturing method by using said electron beam apparatus
An electron beam apparatus, in which an electron beam emitted from an electron gun having a cathode and an anode is focused and irradiated onto a sample, and secondary electrons emanated from the sample are directed into a detector, the apparatus further comprising means for optimizing irradiation of the electron beam emitted from the electron gun onto the sample, the optimizing means may be two-stage deflectors disposed in proximity to the electron gun which deflects and directs the electron beam emitted in a specific direction so as to be in alignment with the optical axis direction of the electron beam apparatus, the electron beam emitted in the specific direction being at a certain angle with respect to the optical axis due to the fact that, among the crystal orientations of said cathode, a specific crystal orientation allowing a higher level of electron beam emission out of alignment with the optical axis direction.
US08368013B2 Analyzer, ionization apparatus and analyzing method
An analyzer performs dielectric barrier discharge and ionization of a sample by a reaction between the sample and excited molecules or ions generated by the dielectric barrier discharge at a pressure lower than an atmospheric pressure.
US08368012B2 Guiding charged droplets and ions in an electrospray ion source
Charged spray droplets are guided in a pseudopotential distribution generated by audio frequency voltages at electrodes of a guiding device, focusing the spray droplets toward the axis. An axial electric field profile and an axial flow profile of a drying gas in the guiding device allow the drift of different-sized droplets to be controlled in the longitudinal direction of the guiding device, so that the droplets are roughly equal in size when they leave the guiding device and finally dry up shortly after leaving. As a result, the ions are formed in a relatively small spatial region. Electrostatic potentials guide the analyte ions from this small spatial region to the entrance aperture of the inlet capillary; during this process, very light ions, especially protons and water-proton complexes, can be filtered out by a mobility filter.
US08368007B2 Component for and method of sealing an internal optical compartment, and shock mounting a window, of an imaging reader
An imaging reader for electro-optically reading a target by image capture includes a window supported by a housing, a chassis mounted in the housing and having chassis walls bounding an optical compartment, and an imaging module in the optical compartment for capturing return light from the target through the window. A component seals the optical compartment and protects the window from shock forces. The component is mounted between the window and the chassis walls bounding an opening into the optical compartment, and surrounds a periphery of the window. The component is constituted of a compressible material that is compressed between the window and the chassis walls to isolate and seal the optical compartment from the housing.
US08368005B2 Optical detection method and optical MEMS detector, and method for making MEMS detector
The present invention discloses an optical MEMS detector, comprising: a substrate; at least one photo diode in a region within the substrate; an isolation wall above the substrate and surrounding the photo diode region; and at least one movable part having an opening for light to pass through and reach the photo diode, wherein when the at least one movable part is moved, an amount of light reaching the photo diode is changed.
US08368003B2 Image-capturing module for simplifying optical component and reducing assembly time
An image-capturing module for simplifying optical component and reducing assembly time includes a substrate unit, an image-capturing unit, a cover unit, a light-emitting unit and an optical imaging unit. The image-capturing unit has at least one image-capturing element electrically disposed on the substrate unit. The cover unit has at least one cover element disposed on the substrate unit and covering the image-capturing element, and the cover element has an opening for exposing the image-capturing element. The light-emitting unit has at least one light-emitting element electrically disposed on the substrate unit. The optical imaging unit has a light-guiding element disposed on the cover element for receiving light beams generated by the light-emitting element and an imaging element connected with the light-guiding element and disposed in the opening of the covering element. The light-guiding element and the imaging element are integrated with each other to form one piece.
US08368001B2 Wireless remote detector systems and methods
A system is provided that includes: a sensor device adapted to selectively monitor a plurality of sensors including an electrical sensor adapted to monitor at least one electrical parameter associated with a circuit and a heat sensor adapted to monitor heat, wherein the sensor device includes a wireless transceiver within the sensor device adapted to transmit measurement information from the selected sensor; and a receiver indicator device adapted to wirelessly receive the measurement information from the sensor device, and provide an indication based on the measurement information to a user operating the receiver indicator device.
US08367996B2 Solar sensing system and solar tracking method thereof
This invention discloses a solar sensing system and a solar tracking method thereof. The solar sensing system comprises a solar module, an azimuth sensor unit, an elevation sensor unit and a driving unit. The azimuth sensor unit and the elevation sensor unit are disposed on the surface of the solar module. The azimuth sensor unit senses sunlight to generate an azimuth signal. The driving unit receives the azimuth signal to turn the solar module until the azimuth sensor unit is aligned precisely towards the sunlight. The elevation sensor unit senses the sunlight to generate an elevation signal. The driving unit receives the elevation signal to turn the solar module until the elevation sensor unit is aligned precisely towards the sunlight. If the azimuth sensor unit and the elevation sensor unit are aligned precisely towards the sunlight, the solar module will also be aligned precisely towards the sunlight.
US08367994B2 Optical module, which is able to fire a beam
An optical module is disclosed. The optical module includes: (1) a mirror part for controlling its reflection angle in an analog method; (2) an aperture for controlling an amount of light incident to the mirror part, the aperture being installed facing the mirror part; (3) a detector for detecting an optical signal from a light transmitted from the mirror part; (4) a beam emitter for emitting a beam, the beam emitter being adjacently installed to the optical signal detector; and (5) a controller for controlling the mirror part so as to locate an object, detected by the optical signal detector, at the center portion of the optical signal detector, and for controlling the beam emitter and the mirror part so as to emit a beam from the beam emitter to the object detected by the optical signal detector. The optical module can observe an object both in a wide field of view (FOV) and in detail, effectively track a rapidly moving object, and emit a beam to the object.
US08367993B2 Aerodynamic flight termination system and method
A missile has a flight termination system that includes deployable lift surfaces that deploy forward of a center of gravity of the missile. When deployed, the lift surfaces cause the missile to rotate about its longitudinal axis. This rotation eventually increases in rate until the missile nears a natural roll frequency of the missile. As the missile nears or reaches its natural roll frequency, the missile's nose pitches up, angle of attack diverges and the missile tumbles, resulting in rapid termination of flight by loss of aerodynamic lift, vertical plunging and crashing. The lift surfaces may be curved surfaces that conform to the shape of a fuselage of the missile, prior to the deployment of the lift surfaces. The lift surfaces may be canted slightly relative to a missile longitudinal axis when the lift surfaces are deployed, so as to provide a sufficient rolling moment to overcome aerodynamic damping or resistance (roll drag) of the missile.
US08367988B2 Field director assembly having overheating protection
A field director assembly includes electrically conductive vanes positioned with respect to each other and to a planar support member to prevent overheating of the susceptor in an unloaded microwave oven.
US08367985B2 Mica board electric resistance wire heater and method of use
A mica board heater has a mica board support plate assembly that isolates the mica boards from the frame of the heater. The mica board support plate assembly includes a mica board with openings sized to receive ends of the mica boards that support the resistance wires. The mica board with the specially sized openings is supported by a frame that is attached to the heater frame. By using the mica board support plate assembly, the mica boards are electrically isolated from the frame and without compromising the structural soundness of the frame.
US08367984B2 Energy management of household appliances
A water heater comprises a body defining a chamber for holding water to be heated, an inlet opening and an outlet opening in communication with the chamber for flowing water therethrough and one or more power consuming features/functions including a heater for heating the water within the chamber. A controller is operatively connected to the one or more power consuming features/functions. The controller is configured to receive and process a signal indicative of a utility state. The controller operates the water heater in one of a plurality of operating modes, including at least a normal operating mode and an energy savings mode, in response to the received signal. The controller is configured to at least one of selectively adjust and deactivate at least one of the one or more power consuming features/functions to reduce power consumption of the water heater in the energy savings mode.
US08367982B2 Built-in cooking appliance and installation apparatus for the same
Provided is a built-in cooking appliance. According to the built-in cooking appliance, the inside of the cooking appliance is effectively cooled and the inside can be waterproofed without protruding the top plate above the cabinet. Therefore, cooling efficiency, stability in using, convenience in cleaning, esthetic feeling, and reliability of a product can be improved. The built-in cooking appliance includes a top plate, a main body below the top plate, a fan, a cabinet, a gap portion, and a top frame. At least a heating unit is disposed inside the main body. The fan forms a cooling passage inside the main body. The plate is installed on the cabinet. The gap portion defines at least a portion of the cooling passage, and is formed by at least an edge on one side of the top plate and the cabinet separated from each other. The top frame covers the gap portion.
US08367976B2 Laser heating of aqueous samples on a micro-optical-electro-mechanical system
A system of heating a sample on a microchip includes the steps of providing a microchannel flow channel in the microchip; positioning the sample within the microchannel flow channel, providing a laser that directs a laser beam onto the sample for heating the sample; providing the microchannel flow channel with a wall section that receives the laser beam and enables the laser beam to pass through wall section of the microchannel flow channel without being appreciably heated by the laser beam; and providing a carrier fluid in the microchannel flow channel that moves the sample in the microchannel flow channel wherein the carrier fluid is not appreciably heated by the laser beam.
US08367970B2 Laser machining with laser power controlled as a function of laser motion
A method and device (1) for laser machining vehicle bodies or body parts (2) uses a laser beam (14) that is guided from a laser source (13) to a remote laser tool (15) on a robot hand by a guiding device (16). The robot (4) maintains the laser tool (15) in a suspended manner over the tool (2), at a focal length (F) and at a contact free distance and guides it along a machining path (30). The laser beam (14) is deviated, by movement of the hand axis (IV, V, VI), about a variable deviation angle (α), and the laser source (13), whose power is variable, is controlled according to the movement of the laser beam. The beam deviation of the hand axis (IV, V, VI) can be superimposed on an offset movement of the robot (4).
US08367969B2 Support table frame for high speed laser blanking
The present invention provides an apparatus for laser cutting that comprises a rigid support table frame having a X-axis and a Y-axis, and one or more bridge rail modules running across the Y-axis of the table frame, each bridge rail module comprising at least one hold-down device module. The present invention further provides a process for laser cutting a metal plate using this apparatus.
US08367968B2 System and method for multi-pulse laser processing
Laser pulses are selected from a group of closely spaced laser pulses with an optical modulator by adjusting pulse timing relative to an impingement interval. An adjusted pulse is moved from an impingement interval to a non-impingement interval and is blocked. The blocked laser source is stabilized by running nearly continuously. Pulse selection with multiple laser sources is achieved with a single acousto-optic modulator.
US08367963B2 Method and apparatus for microplasma spray coating a portion of a turbine vane in a gas turbine engine
A method and apparatus for microplasma spray coating a portion of a turbine vane without masking any portions thereof. The apparatus includes a microplasma gun with an anode, cathode, and an arc generator for generating an electric arc between the anode and cathode. An arc gas emitter injects gas through the electric arc. The electric arc is operable for ionizing the gas to create a plasma gas stream. A powder injector injects powdered material into a plasma stream. A localized area of the turbine vane is coated with the powdered material without having to mask the turbine vane.
US08367954B2 Button structure with light transmittance and related electronic device
A button structure includes a pressing portion, and an accommodating portion connected to a side of the pressing portion. An accommodating space is formed inside the accommodating portion. The button structure further includes a protruding portion connected to a side of the accommodated portion for actuating a switch when the pressing portion is pressed, and a light guiding portion. An end of the light guiding portion is disposed above a light source, and the other end of the light guiding portion is disposed inside the accommodating space. The light guiding portion is for guiding light emitted from the light source to project on a bottom of the pressing portion.
US08367952B2 Acceleration sensor
An acceleration sensor is provided. The acceleration sensor contains a first electrically conductive element and a second electrically conductive element. An electrically insulative element is connected to the first electrically conductive element and the second electrically conductive element, where at least a portion of the first electrically conductive element and at least a portion of the second electrically conductive element make contact with the electrically insulative element. At least one electrically conductive spring is located within a cavity of the sensor, wherein the cavity is defined by at least one surface of the first electrically conductive element, at least one surface of the electrically insulative element, and at least one surface of the second electrically conductive element.
US08367948B2 Handheld device
A pair of side keys disposed on a lateral plate casing of a stationary-side rear case in a cellular phone is coupled with a film sheet that is fabricated in a substantially identical length to the length of the pair of side keys. The pair of side keys is coupled with the film sheet by applying double-faced adhesive tapes having adhesive faces on both sides only to both ends of the film sheet.
US08367945B2 Apparatus, system and method for use in mounting electronic elements
The present embodiments provide apparatuses, systems and methods of manufacturing surface mountable devices. Some embodiments provide surface mount devices that comprise a casing comprising a recess formed in the casing and extending into the casing, an insert secured with the casing and extending about the recess defining a portion of a surface of the recess with the insert comprising a reflective surface exposed along the recess, and a plurality of leads partially exposed through the recess.
US08367943B2 Multilayered printed wiring board
A multilayered printed wiring board has a core substrate having a through hole opening with a radius R, a through hole structure formed at the through hole opening and including a lid-shaped conductive structure, a first interlaminar resin insulation layer formed over the core substrate and having a first via hole structure with a bottom radius r, and a second interlaminar resin insulation layer formed over the first interlaminar resin insulation layer and having a second via hole structure. The lid-shaped conductive structure is formed over the core substrate at an end portion of the through-hole opening and covering the end portion of the through-hole opening. The first via hole structure is formed on the lid-shaped conductive structure and has an electroless plated film and an electrolytic plated film. The second via hole structure has an electroless plated film and an electrolytic plated film. The first via hole has a gravity center at or beyond a radius D, where D=(R−r/3) and the radius D is measured from a gravity center of the through-hole opening, and the bottom radius r of the first via hole is larger than a bottom radius of the second via hole.
US08367940B2 Encapsulation device and method, microcapsule incorporating this device
The invention concerns a device for encapsulating an element within a microcavity made on a support (10), this device comprising an encapsulating membrane (12) capable of forming at least one part of the microcavity,characterized in that the device comprises at least one arm which mechanically attaches the membrane to the support, this arm being capable of bending so as to shift the membrane between: an open position in which the membrane overhangs the element to be encapsulated and its periphery defines an aperture extending around the element to be encapsulated, and a shut position in which the periphery of the encapsulation membrane rests on the support to obstruct this aperture.
US08367936B2 Flexible printed circuit board and method for forming monitor
The disclosure relates to a flexible printed circuit board and a method for manufacturing a monitor. The flexible printed circuit board is disposed on a portion of an upper surface of a substrate and is folded to a sidewall and a lower surface of the substrate. The flexible printed circuit board includes a flexible substrate and an insulating layer surrounding the flexible substrate. The insulating layer has an opening at least exposing a portion of the flexible substrate situated relative to the sidewall of the substrate.
US08367934B2 Insulating coating composition and an insulated wire, and a coil formed using the same
An insulating coating composition that improves lubricity without reduction of the varnish adhesion strength and an insulated wire using the insulating coating composition, and a coil using the insulated wire are provided. An insulating coating composition comprises a polyamide-imide resin, which is obtained through a synthetic reaction of isocyanate component with acid component, and a lubricant component, wherein the terminal isocyanate group of the polyamide-imide resin is capped with a blocking agent of higher alcohol having a carbon number of eight or more.
US08367932B2 Flat cable
A flat cable including thin coaxial cables each having a center conductor and a jacket, parallel arranged two-dimensionally in a flat shape, and joined by tangling them with a weft yarn in units of predetermined number of very thin coaxial cables. The flat cable further includes tangling yarns that are arranged parallel along the edges in the width direction of the thin coaxial cables, and the elongation of the weft yarn is greater than that of the tangling yarn. When the very thin flat cable is bent, the bent portion of the weft yarn is elongated, and thereby the bent portion of the very thin coaxial cables can deviate from the mesh formed by the very thin coaxial cables and the weft yarn.
US08367929B2 Microcavity structure and encapsulation structure for a microelectronic device
A microcavity structure including: a first substrate, a cover attached to the first substrate such that a space formed between the cover and the first substrate forms the microcavity, at least one hole passing through the cover, and at least one closing flap of the hole placed inside the microcavity and including at least two portions of materials with different thermal expansion coefficients placed one against the other, at least one first end of the two portions being mechanically linked to the cover, at least a second end of the two portions being free, and at least a part of the closing flap being placed opposite the hole, the two portions being capable of closing or not the hole under the effect of a temperature variation.
US08367928B2 Waterproof mechanism and electronic device having the same
A waterproof mechanism includes a housing having a base wall, at least one door plate, a first waterproof seal, and at least one return spring. The base wall is formed with an opening. The door plate is connected movably to the base wall for closing the opening in the base wall. The door plate is pushable to perform a motion relative to the base wall to thereby open the opening. The first waterproof seal is disposed between the base wall and the door plate and around the opening so as to establish a water-tight seal between the base wall and the door plate. The return spring is disposed between the base wall and the door plate for biasing the door plate to close the opening.
US08367927B2 Waterproofing method for wire and wire having waterproof part formed by the waterproofing method
A waterproofing method is provided for a wire to be arranged in a water susceptible area of a vehicle. An insulating coating layer is removed in a lengthwise intermediate part of the wire to expose a core. A heat shrinkable tube with an inner layer made of a hot-melt waterproofing agent is mounted on the exposed core section and parts of the insulating coating layer adjacent to the exposed core section and heated. As a result, the hot-melt waterproofing agent of the inner layer is melted and infiltrates into clearances between strands of the exposed core section. In addition, negative pressure is introduced into the inside of the insulating coating layer from an end of the wire, thereby sucking the waterproofing agent into the inside of the insulating coating layer to infiltrate the waterproofing agent also between the strands of the core inside the insulating coating layer.
US08367926B2 Electronic apparatus and cover mechanism
An electronic apparatus includes an enclosure defining a connector port, and a cover mechanism. The cover mechanism includes a bracket mounted to the enclosure, a cover rotatably mounted to the bracket to cover or uncover the connector port. The cover includes an elastic lock. When the cover is rotated to cover the connector port, the elastic lock is engaged with a sidewall of the connector port.
US08367925B2 Light-electricity conversion device
Light-electricity conversion devices based on II-VI semiconductor materials are provided. The light-electricity conversion devices are able to cover a wide spectrum range.
US08367924B2 Buried insulator isolation for solar cell contacts
The present invention relates to methods and apparatuses for providing a buried insulator isolation for solar cell contacts. According to certain aspects, the invention places a buried oxide under the emitter of a polysilicon emitter solar cell. The oxide provides an excellent passivation layer over most of the surface. Holes in the oxide provide contact areas, increasing the current density to enhance efficiency. The oxide isolates the contacts from the substrate, achieving the advantage of a selective emitter structure without requiring deep diffusions. The oxide further enables use of screen printing on advanced shallow emitter cells. Positioning of the grid lines close to the openings also enables use of a very thin emitter to maximize blue response.
US08367923B2 System for separating and mixing audio tracks within an original, multi-track recording
The teachings described herein are generally directed to a system, method, and apparatus for learning music through an educational audio track embodied on a computer readable medium. The system can comprise components including a processor, an input device, a database, a transformation module, an emulation recording module, an integration engine, an output module, and an output device, wherein each component is operable in itself to perform it's function in the system and operable with other system components to provide a system to a user for learning music.
US08367914B2 Plants and seeds of hybrid corn variety CH694532
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH694532. The invention thus relates to the plants, seeds and tissue cultures of the variety CH694532, and to methods for producing a corn plant produced by crossing a corn plant of variety CH694532 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH694532.
US08367911B1 Maize variety hybrid X03A112
A novel maize variety designated X03A112 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X03A112 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X03A112 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X03A112, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X03A112. This invention further relates to methods for producing maize varieties derived from maize variety X03A112.
US08367902B2 Plants and seeds of corn variety CV969822
According to the invention, there is provided seed and plants of the corn variety designated CV969822. The invention thus relates to the plants, seeds and tissue cultures of the variety CV969822, and to methods for producing a corn plant produced by crossing a corn plant of variety CV969822 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV969822 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV969822.
US08367900B1 Inbred maize variety PHHHD
A novel maize variety designated PHHHD and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PHHHD with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PHHHD through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PHHHD or a trait conversion of PHHHD with another maize variety. Inbred maize varieties derived from maize variety PHHHD, methods for producing other inbred maize varieties derived from maize variety PHHHD and the inbred maize varieties and their parts derived by the use of those methods.
US08367896B2 Canola cultivar DN051535
The present invention relates to a new and distinctive canola cultivar, designated DN051535. Also included are seeds of canola cultivar DN051535, to the plants, or plant parts, of canola DN051535 and to methods for producing a canola plant produced by crossing the canola DN051535 with itself or another canola cultivar, and the creation of variants by mutagenesis or transformation of canola DN051535.
US08367893B2 Late blight resistance genes and methods
This invention provides novel gene sequences, compositions and methods for enhancing the resistance in crops, in particular but not limited to, potato, to late blight caused by the oomycete pathogen Phytophthora infestans.
US08367891B2 N-terminal XA27 signal anchor and its use for localization of fusion proteins
The present application is directed to a functional signal anchor that localizes a fusion protein to the apoplast of vascular elements in plants. The signal anchor is useful for engineering secretory proteins to the cell wall and or/apoplast of plant cells. The signal anchor is also useful for producing secretory proteins in transgenic plant cells in a bioreactor.
US08367888B2 Mouse λ light chain locus
The present invention provides in a first aspect a mouse in which the λ (lambda) light chain locus has been functionally silenced. In one embodiment, the mouse λ light chain locus was functional silenced by deletion of gene segments coding for the λ light chain locus. In a further aspect, a mouse containing functionally silenced λ and κ (kappa) L chain loci was produced. The invention is useful for the production of antibodies, for example heterologous antibodies, including heavy chain only antibodies.
US08367887B2 Normal-tension glaucoma model and method for evaluation of test substances by using same
It is intended to provide a simple normal-tension glaucoma model capable of spontaneously, age-dependently and surly developing conditions similar to symptoms of normal-tension glaucoma which occurs more frequently in elder people, and a method of evaluating therapeutic effect on normal-tension glaucoma whereby a drug useful in treating and diagnosing can be conveniently screened by using the normal-tension glaucoma model. A normal-tension glaucoma model comprising a nonhuman mammal, which is deficient in a transcriptional regulator NF-κBp50 and thus spontaneously develops the normal-tension glaucoma symptom age-relatedly, an organ or a tissue thereof or cells collected from any of the same. A method of evaluating therapeutic effect on normal-tension glaucoma of a test substance which comprises administering or adding the test substance to the above-described nonhuman mammal, an organ or a tissue thereof or cells collected from any of the same, and measuring a morphological defect, cell count, pressure, the expression amount or activity strength of a protein, the expression amount of a nucleic acid and/or the activity strength of an antibody in the organ, tissue and/or cells as indication(s) for the evaluation.
US08367886B2 Reactive distillation for the dehydration of mixed alcohols
Process for producing alkene(s) from a feedstock containing at least one monohydric aliphatic paraffinic alcohol having from 2 to 5 carbon atoms. The process is carried out by 1 converting the monohydric aliphatic paraffinic alcohol(s) containing 2 to 5 carbon atoms in a reactive distillation column at elevated pressure and temperature into a heads stream having the corresponding same carbon number alkene(s) and ether(s), 2 separating the heads stream from step 1 into an ether(s) enriched stream and an alkene(s) enriched stream, 3 recycling at least part of the ether(s) enriched stream from step 2 as a reflux return to the reactive distillation column, 4 simultaneously separating the alkene(s) enriched stream from step 2 into alkene(s) and ether(s), and 5 recycling at least part of the separated ether(s) from step 4 into the reactive distillation column. An alkene(s) stream from step 4 is then recovered.
US08367884B2 Processes and systems for the staged synthesis of alkyl bromides
Processes and systems for synthesizing hydrocarbon products, such as high molecular weight hydrocarbons, olefins or mixtures thereof, from alkyl bromides wherein one or more streams of alkyl bromides may be reacted in sequential or concurrent stages at different temperatures. The catalyst used in the synthesis stages may be the same or different and at least in one instance is chosen to form hydrocarbon products having a significant C6+ paraffin content. The stages may be conducted in one or more reactors and the catalyst may be deployed in fixed beds or fluidized beds.
US08367883B2 Synthetic naphtha manufacturing method
The present invention relates to a method of manufacturing naphtha, wherein, in hydrogenation of a naphtha fraction which is fractionated from synthetic oil (FT synthetic oil) obtained by Fisher-Tropsch synthesis, the hydrogenised component is recycled and the recycled amount thereof is adjusted to reduce a olefin content in a hydro-refining apparatus whereby heat generation is suppressed and unstable operation of the hydro-refining apparatus can be stabilized. Furthermore, the present invention relates to a method of manufacturing naphtha, wherein a cut point for fractionating a naphtha fraction from FT synthetic oil is adjusted to reduce the amount of olefin in a hydro-refining apparatus whereby unstable operation of the hydro-refining apparatus can be stabilized.
US08367882B2 Synthesis of liquid fuels and chemicals from oxygenated hydrocarbons
Processes and reactor systems are provided for the conversion of oxygenated hydrocarbons to hydrocarbons, ketones, cyclic ethers and alcohols useful as liquid fuels, such as gasoline, jet fuel or diesel fuel, and industrial chemicals. The process involves the conversion of oxygenated hydrocarbons, such as alcohols, ketones, aldehydes, furans, carboxylic acids, diols, triols, and/or other polyols, to C4+ hydrocarbons, cyclic ethers, alcohols and/or ketones, by condensation and/or deoxygenation. The oxygenated hydrocarbons may originate from any source, but are preferably derived from biomass.
US08367881B2 Method for biomass fractioning by enhancing biomass thermal conductivity
A method is described for generating useful chemical intermediates from biomass using a novel pyrolysis reactor that utilizes the inherent thermal properties of carbon under compression as the biomass is subjected to sequential or concurrent temperature ramps. The ramps are sufficient to volatilize and selectively create different components, while the pressure application aids the selective decomposition of the biomass.
US08367880B2 Device and method for continuous hydrate production and dehydration by centrifugal force
Disclosed herein is an apparatus and method for continuously producing and dehydrating gas hydrates. The apparatus includes a gas source, a water source, a reactor, a spinning wheel, and a centrifugal separator. The gas source and the water source are connected to the reactor. Gas and water are respectively supplied from the gas source and the water source into the reactor and react with each other in the reactor to form gas hydrate slurry. The spinning wheel and the centrifugal separator are provided in the reactor. The spinning wheel supplies the formed gas hydrate slurry to the centrifugal separator. The centrifugal separator dehydrates the gas hydrate slurry. Water removed from the gas hydrate slurry by the dehydration of the centrifugal separator is re-supplied into the reactor.
US08367879B2 Method for the preparation of 2 chloro 1,1,1,2,3,3,3 heptafluoropropane
A method of catalytically converting 2,2, dichlorohexafluoropropane (HFC-216aa) into 2 chloro 1,1,1,2,3,3,3 heptafluoropropane (HFC-217ba) including the step of exposing the 2,2 dichlorohexafluoropropane to a chromium-containing catalyst comprising a metal oxide, a halogenated metal oxide or a metal oxyhalide, which chromium-containing catalyst comprises 0.01% to 5.0% by weight zinc or a compound of zinc.
US08367878B2 Method for producing 2-chloro-3,3,3,-trifluoropropene (HCFC-1233xf)
The present invention relates to an improved method for manufacturing 2-chloro-3,3,3,-trifluoropropene (HCFC-1233xf) by reacting 1,1,2,3-tetrachloropropene, 1,1,1,2,3-pentachloropropane, and/or 2,3,3,3-tetrachloropropene with hydrogen fluoride, in a vapor phase reaction vessel in the presence of a vapor phase fluorination catalyst and stabilizer. HCFC-1233xf is an intermediate in the production of 2,3,3,3-tetrafluoropropene (HFO-1234yf) which is a refrigerant with low global warming potential.
US08367875B2 Process for the preparation of m-substituted alkyltoluenes by isomerization with ionic liquids as catalysts
The invention relates to a process for the preparation of m-substituted alkyltoluenes of the formula (I) in which R1 is C1-C5-alkyl, wherein a p-substituted alkyltoluene of the formula (II) in which R1 has the meaning given under formula (I), is isomerized in the presence of ionic liquids to give an m-substituted alkyltoluene of the formula (I). The m-substituted alkyltoluenes obtainable according to the invention are starting compounds for the preparation of fragrances and aroma substances.
US08367865B2 Method and catalyst composition for preparing amide
The present invention provides a catalyst composition for preparing an amide, including an amino acid ionic liquid having a cation of formula (I) and an anion selected from the group consisting of an inorganic acid group, an organic acid group and a combination thereof, wherein the numbers of the anion and the cation are such that the amino acid ionic liquid is electroneutral; and a Bronsted acid. The present invention also provides a method for preparing an amide in the presence of the catalyst composition, and the method has advantages such as decreasing viscosity of ionic liquid, and increasing conversion rate of ketoximes and selectivity of amides.
US08367864B2 Dimeric double metal salts of (−)-hydroxycitric acid, methods of making and uses of same
The present invention relates to soluble dimeric double metal salt compositions of (−)-hydroxycitric acid (“HCA”), as well as methods for making and using the same. The invention provides dimeric double metal salts of group IA and IIA of HCA (hereinafter, “DDM-HCAs”). The present invention provides methods to make DDM-HCAs of the invention which can be employed to alter the polar/ionic qualities of HCA salts and derivatives to improve solubility of HCA compositions. DDM-HCAs of the invention are soluble HCA-containing compositions useful as dietary supplements and suitable for manipulations under those conditions necessary for tabletting, encapsulation, and the production of dry powders, particularly for use as a beverage premix. Methods of use of the composition include treatment for suppression of appetite, for weight loss, for an increase in the rate of fat metabolism, for reduction in blood lipids and postprandial lipemia, and to increase the plasma level of (−)-hydroxycitric acid.
US08367860B2 Method for producing (meth) acrylic acid derivitive
The present invention provides a method for efficiently using an aqueous solution of (meth)acrylic acid at a low concentration formed in a production/storage step of (meth)acrylic acid.In the present invention, a (meth)acrylic acid derivative is produced by using as a raw material an aqueous solution of (meth)acrylic acid formed by one or both of: a device which reduces a pressure of a gas comprising (meth)acrylic acid in production of (meth)acrylic acid; and a device which collects (meth)acrylic acid from a gas comprising (meth)acrylic acid.
US08367857B2 Method for producing isothiocyanate compound having carboxyl group
To provide a novel method for producing an isothiocyanate compound having a carboxyl group(s) from the corresponding amino compound having a carboxyl group(s).A method for producing an isothiocyanate compound which has a carboxyl group(s) and is represented by the formula (2). And the method comprises reacting an amino compound which has a carboxyl group(s) and is represented by the formula (1) (wherein A is e.g. a C6-14 aromatic hydrocarbon group or a C1-12 saturated hydrocarbon group, and B is e.g. a single bond, a C6-14 aromatic hydrocarbon group or a C1-12 saturated hydrocarbon group), in a solvent, with carbon disulfide (CS2) and then with a halogen as a simple substance.
US08367855B2 Process for preparing silylorganoamines
Process for preparing silylorganoamines, which process comprises the following steps: (A) provision of silylorganoamines of the formula I: [R2a(R1O)3-aSiR3]nNH3-n in a reactor, (B) reaction of the silylorganoamines of the formula I in the presence of particulate metallic noble metal at a temperature in the range from 100° C. to 300° C. to form silylorganoamine products of the formula II: [R2a(R1O)3-aSiR3]yNH3-y, where each radical R1 and each radical R2 is selected independently from the group consisting of alkyl, aryl, aralkyl and cycloalkyl radicals having fewer than 20 carbon atoms; R3 is selected from the group consisting of divalent hydrocarbon radicals having fewer than 20 carbon atoms and a=0, 1, 2 or 3; n=1 or n=2 or n=1 and 2; and y=3.
US08367850B2 Benzo-fused thiophene or benzo-fused furan compounds comprising a triphenylene group
Triphenylene containing benzo-fused thiophene compounds are provided. Additionally, triphenylene containing benzo-fused furan compounds are provided. The compounds may be useful in organic light emitting devices, particularly as hosts in the emissive layer of such devices, or as materials for enhancement layers in such devices, or both.
US08367844B2 Microbiocidal heterocycles
The present invention relates to heterocyclic compounds of formula I which have microbiocidal activity, in particular fungicidal activity as well as methods of using the compounds of formula (I) to control microbes: wherein A is x-C(R10R11)—C(═O)—, x-C(R12R13)—C(═S)—, x-O—C(═O)—, x-O—C(═S)—, x-N(R14)—C(═O)—, x-N(R15)—C(═S)—, x-C(R16R17)—SO2— or X—N═C(R30)—, in each case x indicates the bond that is connected to R1; T is CR18 or N; Y1, Y2, Y3, and Y4 are independently CR19 or N; Q is O or S; n is 1 or 2; p is 1 or 2, providing that when n is 2, p is 1. R1 is phenyl, pyridyl, imidazolyl, or pyrazolyl; wherein the phenyl, pyridyl, imidazolyl and pyrazolyl are each optionally substituted by 1 to 3 substituents independently selected from C1-C4 alkyl, C1-C4 haloalkyl, halogen, cyano, hydroxy and amino; R2, R3, R4, R5, R6, R7, R10, R11, R12, R13, R16, R17, R18, R19 and R30 each independently are hydrogen, halogen, cyano, C1-C4alkyl, or C1-C4haloalkyl; R8, R14 and R15 each independently are hydrogen or C1-C4alkyl; and R9 is phenyl, benzyl or group (a): wherein the phenyl, benzyl and group (a) are each optionally substituted with 1 to 3 substituents independently selected from C1-C4 alkyl, C1-C4 haloalkyl, halogen, cyano, hydroxy and amino; or a salt or a N-oxide thereof.
US08367841B2 Processes for the preparation of 1,2,4-oxadiazole benzoic acids
Provided herein are processes for the preparation of compounds useful for the treatment, prevention or management of diseases associated with a nonsense mutation. More specifically, provided herein are processes for the synthesis of 1,2,4-oxadiazoles. In particular, provided herein are processes useful for the preparation of 3-[5-(2-fluorophenyl)-[1,2,4]oxadiazol-3-yl]-benzoic acid.
US08367839B2 Tetrakis(1-imidazolyl) borate (BIM4) based zwitterionic and related molecules used as electron injection layers
Tetrakis(1-imidazolyl)borate (BIm4) based zwitterionic and/or related molecules for the fabrication of PLEDs is provided. Device performances with these materials approaches that of devices with Ba/Al cathodes for which the cathode contact is ohmic. Methods of producing such materials, and electron injection layers and devices containing these materials are also provided.
US08367836B2 Pyridinone antagonists of alpha-4 integrins
The present invention provides compounds that are alpha4 integrin antagonists having a structure according to the following formula: or a tautomer, mixture of tautomers, salt or solvate thereof, wherein Cy, ring A, m, n, p, R1, R2, R3, R4, R5 and R6 are defined in the specification. The invention further provides pharmaceutical compositions including the compounds of the invention as well as methods of making and using the compounds and compositions of the invention, e.g., in the treatment and prevention of various conditions and disorders, such as Crohn's disease and ulcerative colitis.
US08367834B2 Process for preparing Montelukast and salts thereof
A method for the preparation of montelukast and salts thereof has been described. The method comprises of following steps: (a) (S)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-isopropenylphenyljpropyl methane sulphonate (styrene mesylate salt) (b) coupling with 1-(mercaptomethyl)cyclopropane acetic acid followed by salification with an amine gives styrene amine salt (c) Converting styrene amine salt to Montelukast amine salt (d) Converting Montelukast amine salt to Montelukast free acid and or its required alkali/alkaline salt.
US08367828B2 PPAR active compounds
Compounds are described that are active on PPARs, including pan-active compounds. Also described are methods for developing or identifying compounds having a desired selectivity profile.
US08367827B2 Process for preparing hydrocodone using a super acid
The present disclosure generally relates to a process for converting a fused, tricyclic compound to a fused, tetracyclic compound that includes a furan ring therein. More particularly, the present disclosure related to a process for preparing a hydrocodone compound, or a compound structurally related thereto, and in particular (+)-hydrocodone, by subjecting a structurally corresponding sinomenine starting compound to a super acid-assisted furan ring closure reaction.
US08367819B2 Synthesis of caprolactam from lysine
In various embodiments, the present invention can involve a method of synthesizing α-amino-ε-caprolactam. The method can comprise heating a salt of L-lysine in a solvent comprising an alcohol. In other embodiments, the present invention can involve methods for synthesizing ε-caprolactam. The methods can comprise heating a salt of L-lysine in a solvent comprising an alcohol and deaminating the reaction product. In various embodiments, the invention can include methods of converting biomass into nylon 6. The methods can comprise heating L-lysine in a solvent comprising an alcohol to produce α-amino-εcaprolactam, deaminating to produce ε-caprolactam and polymerizing into nylon 6, wherein the L-lysine is derived from the biomass. In other embodiments, the present invention can include methods of making nylon 6. The methods can comprise synthesizing ε-caprolactam and then polymerizing, wherein the ε-caprolactam is derived from L-lysine.
US08367815B2 Modular polynucleotides for ligand-controlled regulatory systems
The invention provides an improved design for the construction of extensible nucleic acid-based, ligand-controlled regulatory systems, and the nucleic acid regulatory systems resulting therefrom. The invention contemplates improving the design of the switches (ligand-controlled regulatory systems) through the design of an information transmission domain (ITD). The improved ITD eliminates free-floating ends of the switching and the competing strands, and localizes competitive hybridization events to a contiguous strand of competing and switching strands in a strand-displacement mechanism-based switch, thereby improving the kinetics of strand-displacement. The improved regulatory systems have many uses in various biological systems, including gene expression control or ligand-concentration sensing.
US08367808B2 Methods, devices, kits and compositions for detecting whipworm
Methods, devices, kits and compositions for detecting the presence or absence of whipworm in a fecal sample are disclosed herein. The methods, devices, kits and compositions of the present invention may be used to confirm the presence or absence of whipworm in a fecal sample from a mammal that may also be infected with one or more of hookworm, roundworm, and heartworm. Confirmation of the presence or absence of whipworm in the mammal may be made, for example, for the purpose of selecting an optimal course of treating the mammal and/or for the purpose of determining whether the mammal has been rid of the infection after treatment has been initiated.
US08367801B2 Proteinaceous compounds
A purified novel peptide micrin and its fragments are disclosed. The molecule has hormonal functions and has wide-ranging biological effects. Several uses are disclosed including its therapeutic potential in tissue reduction, tumour suppression, infertility and senescence. A micrin-recognising antibody and the micrin gene are also disclosed.
US08367800B2 Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
The invention provides novel guanylate cyclase-C agonist peptides and their use in the treatment of human diseases including gastrointestinal disorders, inflammation or cancer (e.g., a gastrointestinal cancer). The peptides can be administered either alone or in combination with an inhibitor of cGMP-dependent phosphodiesterase. The gastrointestinal disorder may be classified as either irritable bowel syndrome, constipation, or excessive acidity etc. The gastrointestinal disease may be classified as either inflammatory bowel disease or other GI condition including Crohn's disease and ulcerative colitis, and cancer.
US08367795B2 Antiseptic material and a method for the production and use thereof
The invention relates to chemical industry, in particular to a substance with antiseptic properties and to a method for obtaining and use thereof. The inventive substance can be used as a filtering material or an additive for the mixture of filtering materials, or as a component of filtering composites used for disinfection and purification of liquids, preferably drinking water, or gases. The inventive antiseptic material consists of a solid non-water soluble cross-linked polymer material, which comprises chlorine atoms reversibly bound with nitrogen atoms and is characterized by the following general formula: M(F)1.0-5.5(Ph)0.6-1.0Cl-4.2, where M is melamine, F—bridge and terminal groups—formaldehyde derivatives, Ph—phosphorus with oxidation level +5, Cl—chlorine atoms bound with nitrogen atoms, wherein the above-mentioned material is cross-linked by binding phosphorus-containing ions with melamine links of polymer chains.
US08367783B2 Process for improving the polymerization of ethylene and one or more optional comonomer(s) in a polymerization loop reactor
The present invention relates to a process for improving the polymerization of ethylene and one or more optional co-monomer(s) in a polymerization loop reactor characterized in that said process comprises the step of controlling the hydrogen/monomer ratio along the path of the reactor by multiple, spatially separated, feeding of hydrogen along the path of the loop reactor. In particular, the invention provides a process for controlling, and preferably narrowing, the molecular weight distribution of the produced polymer particles. In another aspect, the invention relates to a polymerization loop reactor suitable for the polymerization process of ethylene and an optional olefin co-monomer, wherein the molecular weight distribution of the produced ethylene polymer can be controlled.
US08367780B2 Aliphatic polyester copolymer, method for preparing the same and polylactic acid resin composition using the same
A block or graft copolymer including a thermoplastic resin segment and as an aliphatic polyester segment is provided. The copolymer can be used as a compatibilizer for a resin alloy comprising polylactic acid, which can reduce the consumption of petroleum raw materials.
US08367776B2 Perfluoroelastomer compositions and methods of preparing same
The present invention includes crosslinked perfluoroelastomeric compositions and molded articles formed from a cross-linkable perfluoroelastomeric composition having a first curable perfluoropolymer having a cure site monomer and a second perfluoropolymer having a cure site monomer. The molar ratio of the tetrafluoroethylene monomer to perfluoroalkylvinyl ether in one perfluoropolymer is about 0 to 100 to about 65 to 35 in the perfluoropolymer. The molar ratio of the tetrafluoroethylene monomer to the perfluoroalkylvinyl ether monomer in the second polymer is about 65:35 to about 95:5 in the second perfluoropolymer. The composition further includes a curative. One fluorine-containing elastomer composition herein, having a short crosslinking time, has perfluoroelastomers (A) having a tetrafluoroethylene unit, a perfluoralkylvinyl ether unit (a) and a monomer unit (b) having at least one kind selected from the group consisting of a nitrile group, a carboxyl group and an alkoxycarbonyl group, wherein the composition has two or more kinds of perfluoroelastomers (A) having differing contents of perfluoroalkylvinyl ether unit (a).
US08367775B2 Modified conjugated diene-vinyl aromatic copolymer and method for manufacturing the same
A modified conjugated diene-vinyl aromatic copolymer and a method for manufacturing the same are provided. The modified conjugated diene-vinyl aromatic copolymer is formed by modifying a conjugated diene-vinyl aromatic copolymer by reacting with a first modifier in a solvent and then reacting with a second modifier. The solvent includes an organic alkali metal initiator.
US08367770B2 Acrylate-vinyl aromatic-unsaturated nitrile graft copolymer with excellent impact strength, colorability, and weatherability, and thermoplastic resin composition containing the same
One aspect of the invention relates to an acrylate-vinyl aromatic-unsaturated nitrile graft copolymer. The acrylate-vinyl aromatic-unsaturated nitrile graft copolymer can include: a double layered rubbery polymer comprising an inner core layer of alkylacrylate-vinyl aromatic copolymer and an outer core layer of alkylacrylate polymer; and a vinyl aromatic-unsaturated nitrile copolymer shell layer grafted onto the double layered rubbery polymer. Another aspect of the invention relates to a weatherable thermoplastic resin composition including the foregoing acrylate-vinyl aromatic-unsaturated nitrile graft copolymer.
US08367759B2 High post consumer content mineral filler based on micronized recycled asphalt paving and thermoplastic compositions and polymeric emulsions derived from same
A micronized filler for use in thermoplastic compositions, polymeric emulsions and other end products can include micronized recycled asphalt paving. The recycled asphalt paving filler can include calcium carbonate, calcium magnesium carbonate and silicon dioxide. The filler can have a particle size of 325 mesh screen, and a specific gravity of 2.4. The filler increases the post consumer content of various end products.
US08367758B2 Water-based cement for producing tyres
A water-based cement for producing tyres includes 5 to 80% by weight of water, 10 to 60% by weight of a cross-linkable unsaturated-chain polymer base, 1 to 15% by weight of emulsifiers, and a quantity of metal oxide depending on the desired degree of adhesion.
US08367757B2 Polymer composite material, optical material including the same, and thermoplastic aromatic polymer
The present invention develops a new thermoplastic aromatic polymer in which metal oxide particles can be uniformly dispersed even without any special functional group in the polymer, and provides a high-performance polymer composite material including the thermoplastic aromatic polymer. A polymer composite material of the present invention includes: a polymer matrix including a thermoplastic aromatic polymer having both an ester bond and an ether bond; and metal oxide particles dispersed in the polymer matrix.
US08367753B2 Polypropylene resin composition for creating fabric texture
According to preferred aspects, the present invention provides a polypropylene resin composition for creating a fabric texture, the polypropylene resin composition comprising: a polypropylene resin containing at least two selected from the group consisting of a homopolypropylene, a propylene-ethylene copolymer, and a high crystalline polypropylene (HCPP); a polypropylene elastomer; an ethylene-α-olefin copolymer; an inorganic filler; a cellulose fiber; and a volcanic rock. A molded product prepared using the polypropylene resin composition of the present invention has matt properties, do not cause odor due to their excellent VOC adsorption capabilities, and have excellent properties such as low temperature impact resistance, scratch resistance, etc.
US08367750B2 Aqueous ink, ink jet recording method, ink cartridge, recording unit and ink jet recording apparatus
The invention provides an aqueous ink comprising a polymer having hydroxyl groups and a pigment, which can provide images excellent in scratch resistance and highlighter resistance and can inhibit the seeping out phenomenon of the polymer and the deterioration of ejection characteristics even when it is stored for a long period of time. The aqueous ink comprises a polymer having hydroxyl groups, a pigment and a water-soluble organic solvent, wherein the water-soluble organic solvent comprises a polyhydric alcohol having a value of number of hydroxyl groups/number of carbon atoms in its molecule of 0.50 or less.
US08367749B2 Coated microspheres and their uses
The invention relates to microspheres coated with a phenolic novolak resin, a process for preparing them, and their use in making foundry shapes, e.g. molds, cores, sleeves, pouring cups, etc., which are used in casting metal parts.
US08367734B1 Stable epinephrine suspension formulation with high inhalation delivery efficiency
A stable suspension aerosol formulation of epinephrine is suitable for administration through inhalation comprising a therapeutically effective amount of epinephrine, hydrofluorocarbon propellant, co-solvent, surfactant, and antioxidant. The suspension aerosol formulation further comprises [pre-] pre-micronized epinephrine suspended in an alcohol/surfactant solution with hydrofluoroalkane propellant. The suspension formulation provides a highly efficient delivery of drug microparticles into the respirable region of patients' lungs and has the following advantages: lower dosage requirement, minimum alcohol content, with less impurities generated during storage, improved efficacy and safety, and exhibits no ozone depleting potential compared to a formulation containing chlorofluorocarbon.
US08367731B2 Peritoneal dialysis fluid
The present invention concerns a peritoneal dialysis fluid with enhanced ultrafiltration during the dialysis dwell period. According to the present invention this is achieved by a peritoneal dialysis fluid comprising sodium ions, osmotic agent and a buffer, characterised in that it comprises citrate at a level of 4 to 10 mM in a final solution ready for use.
US08367730B2 Composition of amino acids for sublingual applying for enhanced skin integument repigmentation in vitiligo and method of its administration
The task of this invention is in use of composition containing natural metabolites—amino acids, and in method of its administration which make it possible to increase skin repigmentation through sulfurcontaining compounds rise and activation of endogenic metabolic reactions, and to get persistent normalization of melanogenesis thus improving skin integument and as a consequence patient's quality of life.Composition includes L cystine, L glutamic acid and glycine in the following quantity, mg: L cystine85 ± 10%, L glutamic acid85 ± 10%, Glycine85 ± 10% The amino acid composition mentioned above must be administered 3 times a day for 5 weeks independent of meal in accordance with method of increase of skin integument repigmentation in vitiligo. The course can be repeated in 4-5 weeks.
US08367724B2 Ester compound and use thereof
An ester compound represented by the formula (1): wherein R represents a C1-C4 alkyl group or a C3-C4 alkenyl group, and A represents a single bond or an oxygen atom, has an excellent pest controlling efficacy, and it is useful as an active ingredient of a pest controlling agent.
US08367722B2 Methods of using prodrugs of pregabalin
The present invention provides prodrugs of GABA analogs, pharmaceutical compositions of prodrugs of GABA analogs and methods for making prodrugs of GABA analogs. The present invention also provides methods for using prodrugs of GABA analogs and methods for using pharmaceutical compositions of prodrugs of GABA analogs for treating or preventing common diseases and/or disorders.
US08367720B2 Andrographolide derivatives and use thereof in manufacture of medicaments
The present invention relates to an andrographolide derivative of the formula (I), wherein R1, R2 and R3 are same or different substituents selected from hydrogen, substituted or unsubstituted organic acid radicals, inorganic acid radicals, alkyl, aryl or heteroaryl, and at least one of R1, R2 and R3 is R-lipoic acid, S-lipoic acid or a mixture thereof, or corresponding dihydrolipoic acids thereof, or N-acetylcysteine radical. The derivative has good antitumor effect, can induce apoptosis of tumor cells, can directly kill Gram-positive bacteria (staphylococcus aureus) and drug resistance bacteria (MRSA5676 and MRSA5677), can inhibit the QS-system of Gram-negative bacteria (Pseudomonas aeruginosa), can inhibit and destroy the formation of biofilm of Pseudomonas aeruginosa; and exhibits significant hypoglycemic effect, so that it can be used in manufacture of medicaments for treatment of cancers, inflammation, diabetes, and bacterial and viral infections.
US08367719B2 Aryl-substituted bridged or fused diamines as modulators of leukotriene A4 hydrolase
Aryl-substituted bridged or fused diamine compounds, pharmaceutical compositions containing them, and methods of using the compounds and the pharmaceutical compositions for leukotriene A4 hydrolase (LTA4H or LTA4H) modulation and for the treatment of disease states, disorders, and conditions mediated by LTA4H activity, such as allergy, asthma, autoimmune diseases, pruritis, inflammatory bowel disease, ulcerative colitis, and cardiovascular disease, including atherosclerosis and prevention of myocardial infarction.
US08367717B2 High performance solution processable semiconductor based on dithieno [2,3-D:2′, 3′-D′]benzo[1,2-B:4,5-B′] dithiophene
Dithienobenzodithiophenes of general formula (I) in which R1 to R6 are each independently selected from a) H, b) halogen, c) —CN, d) —NO2, e) —OH, f) a C1-20 alkyl group, g) a C2-20 alkenyl group, h) a C2-20 alkynyl group, i) a C1-20 alkoxy group, j) a C1-20 alkylthio group, k) a C1-20 haloalkyl group, I) a —Y—C3-10 cycloalkyl group, m) a —Y—C6-14 aryl group, n) a —Y-3-12 membered cyclo-heteroalkyl group, or o) a —Y-5-14 membered heteroaryl group, wherein each of the C1-20 alkyl group, the C2-20 alkenyl group, the C2-20 alkynyl group, the C3-10 cycloalkyl group, the C6-14 aryl group, the 3-12 membered cyc-loheteroalkyl group, and the 5-14 membered heteroaryl group is optionally substituted with 1-4 R7 groups, wherein R1 and R3 and R2 and R4 may also together form an aliphatic cyclic moiety, Y is independently selected from divalent a C1-6 alkyl group, a divalent C1-6 haloalkyl group, or a covalent bond; and m is independently selected from 0, 1, or 2. The invention also relates to the use of the dithienobenzodithiophenes according to any of claims 1 to 4 as semiconductors or charge transport materials, as thin-film transistors (TFTs), or in semiconductor components for organic light-emitting diodes (OLEDs), for photovoltaic components or in sensors, as an electrode material in batteries, as optical waveguides or for electrophotography applications.
US08367715B2 Pyrazole derivatives, preparation thereof, and therapeutic use thereof
The invention relates to pyrazole derivatives of general formula (I): in which X represents chlorine or fluorine; to a process for preparing said derivatives, and to therapeutic uses of said derivatives.
US08367713B2 Inhibition and dispersion of bacterial biofilms with imidazole-triazole derivatives
Disclosure is provided for imidazole-triazole derivative compounds such as those given in Formulas (I)-(VI) that prevent, remove and/or inhibit the formation of biofilms, compositions comprising these compounds, devices comprising these compounds, and methods of using the same.
US08367712B2 Substituted amide beta secretase inhibitors
Disclosed are novel compounds of the formula or a pharmaceutically acceptable salt or solvate thereof, wherein R1, R2, R3, R4 and X are as defined in the specification. Also disclosed are pharmaceutical compositions comprising the compounds of formula I.Also disclosed are methods of treating cognitive or neurodegenerative diseases such as Alzheimer's disease.Also disclosed are methods of treating a cognitive or neurodegenerative disease comprising administering to a patient I need of such treatment a combination of at least one compound of formula I and at least one compound selected from the group consisting of β-secretase inhibitors other than those of formula I, HMG-CoA reductase inhibitors, gamma-secretase inhibitors, non-steroidal anti-inflammatory agents, N-methyl-D-aspartate receptor antagonists, cholinesterase inhibitors and anti-amyloid antibodies.
US08367708B2 Phenyl-isoxazol-3-ol derivative
The present invention relates to a compound represented by formula (I), which has a GPR120 agonist action and thus is useful for treatment of diabetes mellitus or hyperlipidemia, or a pharmaceutically acceptable salt thereof. In the formula, (AA) represents a phenyl or the like, which may be substituted with a lower alkoxy group or the like; (BB) represents a divalent group or the like, derived by removal of two hydrogen atoms from a benzene which may be substituted with a halogen atom or the like; X represents a spacer having a main chain composed of 1-8 carbon atoms wherein 1-3 carbon atoms in the main chain may be substituted with an oxygen atom or the like; and Y represents a hydrogen atom or the like.
US08367707B2 Pest control agents
Disclosed is a composition for use as a pest control agent, comprising a compound represented by formula (I) or an agriculturally and horticulturally acceptable salt thereof as active ingredient and an agriculturally and horticulturally acceptable carrier:
US08367699B2 Tetrahydro-isoquinolines
The present invention provides a compound selected from compounds of formula (A) as ligand binding to the HDM2 protein, inducing apoptosis and inhibiting proliferation, and having therapeutic utility in cancer therapy and prevention. Compounds of formula (A) can be used as therapeutics for treating stroke, myocardial infarction, ischemia, multi-organ failure, spinal cord injury, Alzheimer's Disease, injury from ischemic events and heart valvular degenerative disease. Moreover, compounds of formula (A) can be used to decrease the side effects from cytotoxic cancer agents, radiation and to treat viral infections.
US08367698B2 3-substituted sulfonyl piperidine derivative
[Problem] There is provided a compound useful as a preventive or remedy for cardiovascular disease, neurologic disease, metabolic disease, reproductive disease, and digestive disease.[Means for Resolution] A compound or a pharmaceutically acceptable salt thereof represented by the following Formula (I) wherein Z represents wherein n1, n2, and n3 are 0, 1, or 2, respectively; R1 represents C1-6 alkyl, C3-8 cycloalkyl, or the like; R2 represents aryl or heteroaryl; R3 represents a hydrogen atom, C1-6 alkyl, or the like; and M1, M2, M3, and M4 independently represent a hydrogen atom, C1-6 alkyl, or the like, or M1, together with M2, M3, or M4, forms —CH2— or the like.
US08367697B2 Kinase inhibitors
The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.
US08367691B2 Modulators of muscarinic receptors
The present invention relates to modulators of muscarinic receptors. The present invention also provides compositions comprising such modulators, and methods therewith for treating muscarinic receptor mediated diseases.
US08367690B2 Aminopyridine derivatives having aurora a selective inhibitory action
The present invention relates to a compound of Formula (I): wherein: R1 is H, —NHCOOR1a, C5-6 cycloalkyl, or phenyl; where the cycloalkyl and phenyl each independently may be substituted with one to three of the same or different substituents selected from R10; R1a is C1-3 alkyl which may be substituted with one to three of the same or different substituents selected from F and Cl; R2 is H, —COOH, —CH2 COOH, —COOR2a, or —CH2COOR2a; R2a is C1-2 alkyl, where the alkyl may be substituted with one to three of the same or different substituents selected from halogen atoms; R3 is H, C1-6 alkyl, where the alkyl may be substituted with one to three of the same or different substituents selected from R11; R10 is F, Cl, CF3, or C1-2 alkyl; R11 is halogen atom, hydroxy, or cyano; W is selected from: W2a is H, halogen atom, cyano, C1-2 alkyl, or C3-5 cycloalkyl, or a pharmaceutically acceptable salt or ester thereof.
US08367680B2 Antibacterial small molecules and methods for their synthesis
The present invention relates generally to compounds providing antibacterial therapeutic agents and preparations, and related methods of using and making antibacterial compounds. Antibacterial compounds of the present invention include chalcone, alkylpyrimidine, aminopyrimidine and cyanopyridine compounds and derivatives thereof exhibiting minimum inhibitory concentrations (MIC) similar to or less than conventional antibacterial compounds in wide use.
US08367671B2 Pyrazolo[3.4-B]pyrazine compounds as p38 modulators and methods of use as anti-inflamatory agents
The present invention comprises a new class of compounds useful for the prophylaxis and treatment of protein kinase mediated diseases, including inflammation and related conditions. The compounds have a general Formula I wherein A1, B, R1, R2, R3, R4, R5 and n are defined herein. The invention also comprises pharmaceutical compositions including one or more compounds of Formula I, uses of such compounds and compositions for treatment of p38 map kinase mediated diseases including rheumatoid arthritis, psoriasis, chronic obstructive pulmonary disease, pain and other inflammatory disorders, as well as intermediates and processes useful for the preparation of compounds of Formula I.
US08367670B2 Modulators of toll-like receptors
Provided are modulators of TLRs of Formula II: pharmaceutically acceptable salts thereof, compositions containing such compounds, and therapeutic methods that include the administration of such compounds.
US08367667B2 Pyrrole derivatives as pharmaceutical agents
Compounds, compositions and methods for modulating the activity of receptors are provided. In particular compounds and compositions are provided for modulating the activity of receptors and for the treatment, prevention, or amelioration of one or more symptoms of disease or disorder directly or indirectly related to the activity of the receptors.
US08367665B2 Estrogen receptor ligands
The invention provides a compound of formula (I) or a pharmaceutically acceptable ester, amide, carbamate, solvate or salt thereof, including a salt of such an ester, amide or carbamate, and a solvate of such an ester, amide, carbamate or salt. The invention also provides also provides the use of such compounds in the treatment or prophylaxis of a condition associated with a disease or disorder associated with estrogen receptor activity, wherein R1, R2, R3, R4, R5 and R6 are as defined in the specification.
US08367661B2 Heterocyclic sulfonamides
Certain substituted sulfonamide derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
US08367659B2 Oxazinyl isoflavonoid compounds, medicaments and use
The invention provides oxazinyl isoflavonoid compounds and compositions containing same, methods for their preparation and their use as therapeutic agents particularly as cardioprotective, anti-inflammatory, anti-oxidant and chemotherapeutic agents.
US08367658B2 Pyrazin-2-yl-pyridin-2-yl-amine and pyrazin-2-yl-pyrimidin-4-yl-amine compounds and their use
The present invention pertains generally to the field of therapeutic compounds, and more specifically to certain biarylamine compounds (referred to herein as BAA compounds), and especially certain pyrazin-2-yl-pyridin-2-yl-amine and pyrazine-2-yl-pyrimidin-4-yl-amine compounds, which, inter alia, inhibit Checkpoint Kinase 1 (CHK1) kinase function. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit CHK1 kinase function, and in the treatment of diseases and conditions that are mediated by CHK1, that are ameliorated by the inhibition of CHK1 kinase function, etc., including proliferative conditions such as cancer, etc., optionally in combination with another agent, for example, (a) a DNA topoisomerase I or II inhibitor; (b) a DNA damaging agent; (c) an antimetabolite or TS inhibitor; (d) a microtubule targeted agent; and (e) ionising radiation.
US08367657B2 Processes for preparing 3-benzazepines
The present invention provides processes and intermediates for the preparation of 3-benzazepines and salts thereof which can be useful as serotonin (5-HT) receptor agonists for the treatment of, for example, central nervous system disorders such as obesity.
US08367656B2 Polymorphs of 7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid S,S dioxide and methods of making and using the same
Disclosed herein are novel polymorphs of 7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid S,S-dioxide. Also described herein are novel pharmaceutical compositions comprising one or more 7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid S,S-dioxide polymorphs, methods of making, and related methods of treatment.
US08367655B2 Pyridoindolobenzox—and thiazepine derivatives and uses thereof
The present invention discloses pyridoindolobenzox- and thiazepine compositions of Formula 1, wherein A is —CH(R9)—X—, —XCH(R9)—; —CO—X— or —X—CO—; X is —O—, —S—, —SO—, or —SO2—. Y is a single bond or a double bond. D and E are independently —(CH2)n—; and ‘n’ varies from 0 to 2. R1 to R9 are various electron donating, electron withdrawing, hydrophilic, or lipophilic groups selected to optimize the physicochemical and biological properties of compounds of Formula I.
US08367654B2 8-AZA tetracycline compounds
The present invention is directed to a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. The variables for Structural Formula I are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula I and its therapeutic use.
US08367648B2 Substituted 16,17-annellated steroid compounds for use in womens healthcare
The present invention relates to substituted steroid compounds having the formula Wherein R1 is H or halogen; R2 is H, (1C-4C)alkyl, (1C-4C)acyl, glucuronyl or sulfamoyl; R3 is H or halogen; R4 is H, (1C-4C)alkyl, (2C-4C)alkenyl or (2C-4C)alkynyl; R5 is methyl or ethyl; R6 is H or methyl; R7 is H or methyl; R8 is H or acyl for use in the treatment and prevention of endometriosis, for contraception, for hormonal therapy in perimenopausal and post-menopausal women, for the treatment of osteoporosis and for the treatment uterine fibroids and other menstrual-related disorders, such as dysfunctional uterine bleeding.
US08367647B2 Treatment of meconium aspiration syndrome with estrogens
One aspect of the present invention relates to the use of an estrogen in the treatment of Meconium Aspiration Syndrome (MAS) in a newborn infant, said treatment comprising administering an effective amount of estrogen to said newborn infant within 7 days after birth. The present treatment offers the advantage that estrogens can be administered using non-invasive modes of administration, e.g. oral or rectal administration. Other aspects of the present invention relate to a suppository for use in newborn infants comprising at least 1 μg of estrogen and to an oral applicator comprising a container holding an aqueous liquid containing micronised estetrol and a metering dispenser for metering the liquid into the oral cavity of a newborn infant.
US08367646B2 Steroid compounds and treatment methods
The invention provides methods to treating conditions such as prostate cancer, or for ameliorating one or more symptoms associated with prostate cancer, or for agents that modulate the biological activity of the androgen receptor. The invention also provides methods and compositions suitable for therapeutic applications.
US08367643B2 Surfactant lipids, compositions thereof and uses thereof
The invention generally relates to methods to inhibit inflammation or pathogen infection by administering at least one anionic lipid or compositions comprising at least one anionic lipid to an individual. The invention also relates to methods to prevent or inhibit respiratory syncytial virus (RSV) infection by administering at least one anionic lipid or compositions comprising at least one anionic lipid to an individual. The invention further relates to compositions comprising randomly mixed surfactant lipids and methods to produce the compositions.
US08367639B2 Hydrogels with covalent and noncovalent crosslinks
A method for targeted delivery of therapeutic compounds from hydrogels is presented. The method involves administering to a cell a hydrogel in which a therapeutic compound is noncovalently bound to heparin. The hydrogel may contain covalent and non-covalent crosslinks.
US08367631B2 Pharmaceutical composition which improves in vivo gene transfer
A pharmaceutical composition, including at least one nucleic acid, a Tyrode's medium having 140 mM NaC1, 6 mM KC1, 3 mM CaC12, 2 mM MgC12, 10 mM Hepes, pH 7.4, and 10 mM glucose; and a tetrafunctional copolymer of formula (I): where x and y represent, independently of one another, an integer of between 1 and 500, the tetrafunctional copolymer is in a form of a mineral salt wherein said tetrafunctional copolymer is in a cationic form. The compound of formula (I) has a molecular weight of between 1,000 and 25,000 g/mol and an EO/PO ratio of 0.8 to 1.2.
US08367630B2 Method for inhibiting expression of a protein in a hepatocyte
A method of screening a candidate compound for susceptibility to biliary excretion by a hepatocyte transport protein. In some embodiments the method can comprise inhibiting expression of the transport protein. Expression of the transport protein can be inhibited through introduction of a RNA having a sequence corresponding to a coding strand of the gene encoding the transport protein into the hepatocyte.
US08367624B2 Treatment of plants, fruits and vegetables to increase growth, eliminate insects and increase shelf-life with aloe vera gel
The present invention includes compositions and methods for the treatment of plants against pathogens, elimination of insects and to increase the shelf-life of fruits and vegetables that includes coating the plant with undiluted aloe vera gel.
US08367621B2 Methods and compositions related to internalizing RGD peptides
Disclosed are compositions and methods useful for targeting tissue undergoing angiogenesis or to cells or tissue expressing αv integrins. The compositions and methods are based on peptide sequences that selectively bind to and home to tissue undergoing angiogenesis or to cells or tissue expressing αv integrins in animals. The disclosed targeting is useful for delivering therapeutic and detectable agents to tissue experiencing angiogenesis or to cells or tissue expressing αv integrins.
US08367619B2 Methods for promoting elastogenesis and elastin fiber formation by increasing tropoelastin expression
Compositions and methods are provided for promoting elastin fiber formation (elastogenesis) in a cell, including methods that comprise contacting a cell that is capable of elastogenesis with (i) a mutated biglycan polypeptide that lacks chondroitin sulphate proteoglycan chains, (ii) a versican V3 isoform polypeptide that lacks most or all of the polypeptide regions encoded by one or more of exons 4, 5 or 6 or by exons 9-10 or 11-13, and/or with (iii) metastatin.
US08367613B2 Resuscitation fluid
A method for treating conditions related to lack of blood supply with a lipid based resuscitation fluid is disclosed. The resuscitation fluid contains a lipid component and an aqueous carrier. The lipid component forms an emulsion with the aqueous carrier. The resuscitation fluid can be used to increase the blood pressure and to carry oxygen to tissues. The resuscitation fluid can also be used for preserving the biological integrity of donor organs for transplantation.
US08367612B2 Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
Non-natural amino acids and polypeptides that include at least one non-natural amino acid, and methods for making such non-natural amino acids and polypeptides, are disclosed. The non-natural amino acids, by themselves or as a part of a polypeptide, can include at least one oxime, carbonyl, dicarbonyl, and/or hydroxylamine group. Methods for making, modifying, and purifying the non-natural amino acid polypeptides are also disclosed. Further, methods for using such non-natural amino acid polypeptides and modified non-natural amino acid polypeptides, including therapeutic, diagnostic, and other biotechnology uses, are disclosed.
US08367610B2 Method of treating cravings by administration of nerve growth factor
A method for administering nerve growth factor to treat cravings is provided. Pharmaceutical compositions for the treatment of cravings comprising nerve growth factor are also provided.
US08367608B2 Method for promoting secretion of glucagon-like peptide-1 by administering κ-casein
The invention relates to a GLP-1 secretagogue and an inhibitor of postprandial rise in blood glucose, containing κ-casein as an active ingredient, and a food or drink for promoting GLP-1 secretion and an inhibitory food or drink of postprandial rise in blood glucose, containing a milk-derived casein protein wherein κ-casein accounts for 60% by mass or more of the milk-derived casein.
US08367607B2 Oxyntomodulin peptide analogue
The present invention provides an Oxyntomodulin peptide analogue useful in the treatment of diabetes and/or obesity.
US08367606B2 Method and compositions for prevention and treatment of diabetic and aged skin
Method and compositions are provided for treating or preventing a skin pathology or disorder associated with diabetes and/or aging, by topical administration of at least one agent capable of restoring an impaired physiological condition of the skin associated with said skin pathology or disorder. Examples of such agents include PKC modulating agents, various adipokines and insulin signaling related molecules. In particular, restoration of the subcutaneous adipose tissue can overcome many of the diabetic skin pathologies and aging skin disorders and conditions.
US08367602B2 Consensus peptides and a method for inducing biomineralization
The present invention relates to artificial peptides optimized for the induction and/or stimulation of mineralization and/or biomineralization. The invention also relates to the use of these artificial peptides for the induction and/or stimulation of mineralization and/or biomineralization in vivo and in vitro.
US08367600B2 Dimensionally stable solid rinse aid
The present invention is a solid rinse aid composition and methods of making and using the same. The solid rinse aid composition generally includes sodium sulfate and urea as solidification agents and an effective amount of an alcohol ethoxylate compound sheeting agent component and an effective amount of defoamer component. The solid rinse aid composition may also incorporate a preservative system including sodium bisulfate. The solid rinse aid composition may be phosphate-free, aminocarboxylate-free, and GRAS if desired.
US08367594B2 Damage free, high-efficiency, particle removal cleaner comprising polyvinyl alcohol particles
A system, method and an apparatus to remove contaminants from a semiconductor substrate surface includes application of a cleaning material. The cleaning material includes a cleaning solution and a plurality of micron-sized dry polyvinyl particles dispersed in the cleaning solution. The cleaning solution is a single phase polymeric compound that is made of long polymeric chains and exhibits distinct viscoelastic properties. The plurality of micron-sized dry polyvinyl alcohol particles absorb the liquid in the cleaning solution and become uniformly suspended within the cleaning material. The suspended polyvinyl alcohol particles interact with at least some of contaminants on the semiconductor substrate surface to release and remove the contaminants from the substrate surface. The released contaminants are entrapped within the cleaning material and removed with the cleaning material leaving behind a substantially clean substrate surface.
US08367588B2 Selective posttranslational modification of phage-displayed polypeptides
The invention relates to posttranslational modification of phage-displayed polypeptides. These displayed polypeptides comprise at least one unnatural amino acid, e.g., an aryl-azide amino acid such as p-azido-L-phenylalanine, or an alkynyl-amino acid such as para-propargyloxyphenylalanine, which are incorporated into the phage-displayed fusion polypeptide at a selected position by using an in vivo orthogonal translation system comprising a suitable orthogonal aminoacyl-tRNA synthetase and a suitable orthogonal tRNA species. These unnatural amino acids advantageously provide targets for posttranslational modifications such as azide-alkyne [3+2]cycloaddition reactions and Staudinger modifications.
US08367584B2 Naphthalene isoxazoline compounds for control of invertebrate pests
Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein R1, R2, R3, R4, R5 and R6 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.
US08367581B2 Thermosensitive recording medium with antibacterial property
To provide a thermosensitive recording medium including: a support; a thermosensitive recording layer composed mainly of a leuco dye and a developer, formed on a surface of the support; and at least two antibacterial agents which include a zirconium phosphate antibacterial agent and an imidazole antibacterial agent and which are internally contained in the thermosensitive recording medium.
US08367575B2 High-refractivity low-dispersion optical glass
The invention provides an environment-friendly optical glass with high refractive index, low dispersion and high light transmittance. The optical glass includes 6%-17% of B2O3, 2-10% of SiO2, more than 25% but less than 45% of La2O3, 5-25% of Gd2O3, 0-3% of Nb2O5, more than 19% but less than 27% of Ta2O5, 0-16% of ZnO, 0-5% of BaO, 0-5% of CaO, 0-5% of SrO, 0-9% of ZrO2, 0-8% of Y2O3, 0-8% of Yb2O3, 0-5% of WO3, 0-2% of Li2O, Na2O and K2O, equal to 0.01% but less than 0.1% of Sb2O3 and 0-1% of SnO2 optical glass. The environment-friendly optical glass does not contain GeO2, and has refractive index of 1.85-1.90, Abbe number of 35-45, the corresponding wavelength below 440 nm when transmittance thereof reaches 80% and high transmittance.
US08367574B2 Highly thermally stressable glass for light bulbs and its use
The alkaline earth metal aluminosilicate glass for light bulbs with molybdenum parts has a composition (in percent by weight on an oxide basis) of SiO2, 56-60; Al2O3, 17-18; B2O3, 0.5-2; MgO, 0.5-2; CaO, >14-15.5; SrO, 0-3; BaO, 6-8; ZrO2, 0-5; CeO2, 0-0.1 and TiO2, 0-0.5.
US08367571B2 Glass strands with low alumina content capable of reinforcing organic and/or inorganic materials
The invention relates to reinforcing glass strands, the composition of which comprises the following constituents within the limits defined below expressed as percentages by weight: SiO262-72% Al2O3 2-10% CaO 7-20% MgO1-7% Na2O + K2O + Li2O  10-14.5% Li2O0-2% BaO + SrO + ZnO0-4% B2O30-4% F20-2% As2O3  0-0.15% These strands are composed of a low-cost glass offering an excellent compromise between the mechanical properties represented by the tensile strength and the fiberizing conditions.The invention also relates to the composites based on organic and/or inorganic material(s) and the aforementioned glass strands.
US08367570B2 Mechanically strong absorbent non-woven fibrous mats
The present invention is generally directed to a liquid entrapping device having the capacity to absorb liquids. More particularly, the present invention is directed to a liquid entrapping device comprising an absorbent component, hydrophilic elastomeric fibrous component in fluid communication therewith, and optionally an adhesive component. The present invention is also directed to a liquid entrapping device having the capacity to absorb liquids while maintaining a suitable degree of mechanical strength. Furthermore, the present invention is generally directed to methods for making and using the foregoing devices and materials.
US08367569B2 Carbon reinforced concrete
A structure may include a plurality of first fiber bundles, a plurality of second fiber bundles, and a plurality of connecting threads. The first fiber bundles may extend substantially parallel to each other. The second fiber bundles may extend substantially parallel to each other and substantially perpendicular to the first fiber bundles. The connecting threads may engage the first fiber bundles and the second fiber bundles such that at least one of the connecting threads is continuously wrapped around each of the first fiber bundles in a helical pattern. The at least one of the connecting threads may extend across a width of each of the second fiber bundles, and may thereby secure the second fiber bundles to each of the first fiber bundles. The first and second fiber bundles may be embedded in a construction material and adapted to reinforce the construction material.
US08367566B2 Method for manufacturing semiconductor device and method for processing substrate
A substrate processing apparatus having a processing chamber for processing a substrate; a processing gas feeding line for feeding a processing gas into the processing chamber; an inert gas feeding line for feeding an inert gas into the processing chamber; an inert gas vent line provided in the inert gas feeding line, for exhausting the inert gas fed into the inert gas feeding line without feeding the inert gas into the processing chamber; a first valve provided in the inert gas feeding line, on a downstream side of a part where the inert gas vent line is provided in the inert gas feeding line; a second valve provided in the inert gas vent line; and an exhaust line that exhausts an inside of the processing chamber.
US08367563B2 Methods for a gate replacement process
A method for fabricating a semiconductor device is disclosed. In one embodiment, the method may include providing a substrate; forming a gate structure including a first dummy gate over the substrate; removing the first dummy gate from the gate structure to form a trench; forming an interfacial layer, high-k dielectric layer, and capping layer to partially fill in the trench; forming a second dummy gate over the capping layer, wherein the second dummy gate fills the trench; and replacing the second dummy gate with a metal gate. In one embodiment, the method may include providing a substrate; forming an interfacial layer over the substrate; forming a high-k dielectric layer over the interfacial layer; forming an etch stop layer over the high-k dielectric layer; forming a capping layer including a low thermal budget silicon over the etch stop layer; forming a dummy gate layer over the capping layer; forming a gate structure; and performing a gate replacement process.
US08367558B2 Method for tuning the work function of a metal gate of the PMOS device
A method for tuning the work function of a metal gate of the PMOS device is disclosed. The method comprises depositing a layer of metal nitride or a metal on a layer of high-k gate dielectric by physical vapor deposition (PVD), as a metal gate; doping the metal gate with dopants such as Al, Pt, Ru, Ga, Ir by ion implantation; and driving the doped metal ions to the interface between the high-k gate dielectric and interfacial SiO2 by high-temperature annealing so that the doped metal ions accumulate at the interface or generate dipoles by interfacial reaction, which in turn tunes the work function of the metal gate. The method can be widely used and its process is simple and convenient, has a better ability of tuning the work function of the metal gate, and is compatible with the conventional CMOS process.
US08367548B2 Stable silicide films and methods for making the same
Highly thermally stable metal silicides and methods utilizing the metal silicides in semiconductor processing are provided. The metal silicides are preferably nickel silicides formed by the reaction of nickel with substitutionally carbon-doped single crystalline silicon which has about 2 atomic % or more substitutional carbon. Unexpectedly, the metal silicides are stable to temperatures of about 900° C. and higher and their sheet resistances are substantially unaffected by exposure to high temperatures. The metal silicides are compatible with subsequent high temperature processing steps, including reflow anneals of BPSG.
US08367547B2 Method for creating a metal crystalline region, in particular in an integrated circuit
The method comprises affixing a thin sheet of crystal (8) onto metal (6) of same type as the sheet but amorphous or of small grain size, deposited in trenches of a substrate (1) to form interconnect lines for example. Annealing progressively imposes the crystalline structure of the sheet onto the lines. When the crystal (8) is removed, highly conductive crystalline lines are obtained since the grains thereof have been greatly enlarged.
US08367546B2 Methods for forming all tungsten contacts and lines
Novel low-resistivity tungsten film stack schemes and methods for depositing them are provided. The film stacks include a mixed tungsten/tungsten-containing compound (e.g., WC) layer as a base for deposition of tungsten nucleation and/or bulk layers. According to various embodiments, these tungsten rich layers may be used as barrier and/or adhesion layers in tungsten contact metallization and bitlines. Deposition of the tungsten-rich layers involves exposing the substrate to a halogen-free organometallic tungsten precursor. The mixed tungsten/tungsten carbide layer is a thin, low resistivity film with excellent adhesion and a good base for subsequent tungsten plug or line formation.
US08367539B2 Semiconductor device and semiconductor device manufacturing method
The semiconductor device manufacturing method includes the steps of attaching two or more solder particles on at least one electrode among a plurality of electrodes of an electronic component, arranging the electrode of the electronic component and an electrode of a circuit board so as to oppose each other, abutting the solder particles attached on a surface of the electrode of the electronic component to the electrode of the circuit board and heating the solder particles, and connecting electrically the electrode of the electronic component and the electrode of the circuit board via two or more solder joint bodies made by melting the solder particles.
US08367524B2 Three-dimensional integrated circuit structure
A method of forming a semiconductor structure includes coupling a semiconductor structure to an interconnect region through a bonding region. The interconnect region includes a conductive line in communication with the bonding region. The bonding region includes a metal layer which covers the interconnect region. The semiconductor structure is processed to form a vertically oriented semiconductor device.
US08367523B2 Method for manufacturing semiconductor light-emitting device and semiconductor light emitting device
A method for manufacturing a semiconductor light-emitting device of the invention includes: forming a semiconductor layer including a light-emitting layer and a first interconnect layer on a major surface of a temporary substrate; dividing the semiconductor layer and the first interconnect layer into a plurality of chips by a trench; collectively bonding each divided portion of the first interconnect layer of a plurality of chips to be bonded not adjacent to each other out of the plurality of chips on the temporary substrate to a second interconnect layer while opposing the major surface of the temporary substrate and the major surface of a supporting substrate forming the second interconnect layer, and collectively transferring a plurality of the bonded chips from the temporary substrate to the supporting substrate after irradiating interfaces between the bonded chips and the temporary substrate and separating the chips and the temporary substrate from each other.
US08367521B2 Manufacture of thin silicon-on-insulator (SOI) structures
The present invention relates to a method of forming a SOI structure having a thin silicon layer by forming a first etch stop layer on a donor substrate, forming a second etch stop layer on the first etch stop layer, wherein the material of the second etch stop layer differs from the material of the first etch stop layer, forming a thin silicon layer on the second etch stop layer, preferably by epitaxy, and bonding the intermediate structure to a target substrate, followed by detaching the donor substrate by splitting initiated in the first etch stop layer at a weakened region and removing the remaining material of the etch stop layers to produce a final ETSOI structure. The invention also relates to the ETSOI structure produces by the described method.
US08367520B2 Methods and structures for altering strain in III-nitride materials
Methods and structures for producing semiconductor materials, substrates and devices with improved characteristics are disclosed. Structures and methods for forming reduced strain structures include forming an interface between a support structure surface and a strained semiconductor layer. The support structure is selectively etched to form a plurality of semiconductor islands with reduced levels of strain.
US08367519B2 Method for the preparation of a multi-layered crystalline structure
This invention generally relates to a process for making a multi-layered crystalline structure. The process includes implanting ions into a donor structure, bonding the implanted donor structure to a second structure to form a bonded structure, cleaving the bonded structure, and removing any residual portion of the donor structure from the finished multi-layered crystalline structure.
US08367518B2 Epitaxial lift off stack having a multi-layered handle and methods thereof
Embodiments of the invention generally relate to epitaxial lift off (ELO) thin films and devices and methods for forming such films and devices. In one embodiment, a method for forming an ELO thin film includes depositing an epitaxial material over a sacrificial layer on a substrate, adhering a multi-layered support handle onto the epitaxial material, and removing the sacrificial layer during an etching process. The etching process further includes peeling the epitaxial material from the substrate and forming an etch crevice therebetween while maintaining compression in the epitaxial material. The method further provides that the multi-layered support handle contains a stiff support layer adhered to the epitaxial material, a soft support layer adhered to the stiff support layer, and a handle plate adhered to the soft support layer. In one example, the stiff support layer may contain multiple inorganic layers, such as metal layers, dielectric layers, or combinations thereof.
US08367511B2 Manufacturing method for high voltage transistor
A manufacturing method for a high voltage transistor includes the following steps. A substrate is provided. A P-type epitaxial (P-epi) layer is provided above the substrate. An N-well is formed in the P-epi layer. A P-well is formed in the P-epi layer. Field oxide (FOX) layers are formed above the P-epi layer. A gate oxide (GOX) layer is formed between the FOX layers. P-type implants are doped into the P-well or N-type implants are doped into the N-well to adjust an electrical function of the high voltage transistor.
US08367506B2 High-k dielectrics with gold nano-particles
A metal oxide semiconductor (MOS) structure having a high dielectric constant gate insulator layer containing gold (Au) nano-particles is presented with methods for forming the layer with high step coverage of underlying topography, high surface smoothness, and uniform thickness. The transistor may form part of a logic device, a memory device, a persistent memory device, a capacitor, as well as other devices and systems. The insulator layer may be formed using atomic layer deposition (ALD) to reduce the overall device thermal exposure. The insulator layer may be formed of a metal oxide, a metal oxycarbide, a semiconductor oxide, or semiconductor oxide oxycarbide, and the gold nano-particles in insulator layer increase the work function of the insulator layer and affect the tunneling current and the threshold voltage of the transistor.
US08367504B2 Method for forming semiconductor fuses in a semiconductor device comprising metal gates
In a replacement gate approach, the semiconductor material of the gate electrode structures may be efficiently removed during a wet chemical etch process, while this material may be substantially preserved in electronic fuses. Consequently, well-established semiconductor-based electronic fuses may be used instead of requiring sophisticated metal-based fuse structures. The etch selectivity of the semiconductor material may be modified on the basis of ion implantation or electron bombardment.
US08367502B2 Method of manufacturing dual gate semiconductor device
The method involves providing a semiconductor substrate comprising first and second regions in which different conductive metal-oxide semiconductor (MOS) transistors are to be formed. A gate dielectric layer above the semiconductor substrate sequentially forming a first metallic conductive layer and a second metallic conductive layer on and above the gate dielectric layer; covering the second region with a mask, and performing ion plantation of a first material into the first metallic conductive layer of the first region. Removing the second metallic conductive layer of the first region and forming a first gate electrode of the first region and a second gate electrode of the second region by patterning the gate dielectric layer and the first metallic conductive layer of the first region, and the gate dielectric layer, the first metallic conductive layer, and the second metallic conductive layer of the second region. The first and second regions of the semiconductor substrate having different work functions because the gate electrodes of the first and second regions have different thicknesses and at least one of the first and second gate electrodes include impurities.
US08367500B1 Method of forming self aligned contacts for a power MOSFET
A method for providing self aligned contacts for a trench power MOSFET is disclosed. The method includes, etching trenches in a substrate through a mask of silicon nitride deposited on an oxide layer, forming a gate oxide layer on the walls of the trenches, applying polysilicon to fill the trenches and to cover the surface of the mask of silicon nitride, removing the polysilicon from the surface of the mask of silicon nitride and applying a photoresist mask to cover a location of a gate bus. The method further includes recessing polysilicon plugs formed in trenches that are located in the active area to form recesses above the polysilicon plugs, filling recesses formed above the polysilicon plugs formed in trenches that are located in the active area with an insulator, applying a fourth photo resist mask to define contact windows that are opened in the nitride layer, and selectively etching the silicon nitride film and leaving flat surfaced oxide buttons covering the trenches that are located in the active area. Moreover, electric contact trenches are defined using self-aligned spacer operations, and a fifth photo resist mask is applied to pattern metal contacts that reach the semiconductor device active areas.
US08367498B2 Fin-like field effect transistor (FinFET) device and method of manufacturing same
A FinFET device and method for fabricating a FinFET device is disclosed. An exemplary method includes providing a semiconductor substrate; forming a fin structure over the semiconductor substrate, the fin structure including a first material portion over the semiconductor substrate and a second material portion over the first material portion; forming a gate structure over a portion of the fin structure, such that the gate structure traverses the fin structure, thereby separating a source region and a drain region of the fin structure, wherein the source and drain regions of the fin structure define a channel therebetween; removing the second material portion from the source and drain regions of the fin structure; and after removing the second material portion, forming a third material portion in the source and drain regions of the fin structure.
US08367493B1 Void free interlayer dielectric
A method of manufacturing a non-volatile memory device includes forming a number of memory cells. The method also includes depositing a first dielectric layer over the memory cells, where the first dielectric layer is a conformal layer having a substantially uniform thickness. The method further includes depositing a second dielectric layer over the first dielectric layer. Together, the first and second dielectric layers form an interlayer dielectric without voids.
US08367488B2 Manufacturing method of flexible semiconductor device
A method includes the steps of preparing a multilayer film 80 formed by sequentially stacking a first metal layer 10, an inorganic insulating layer 20, a semiconductor layer 30, and a second metal layer 40; forming a source electrode 42s and a drain electrode 42d comprised of the second metal layer 40 by etching the second metal layer 40; pressure-bonding a resin layer 50 onto a surface of the multilayer film 80 provided with the source electrode 42s and the drain electrode 42d to burry the source electrode 42s and the drain electrode 42d in the resin layer 50; and forming a gate electrode 10g comprised of the first metal layer 10 by etching the first metal layer 10. The inorganic insulating layer 20g functions as a gate insulating film. The semiconductor layer 30 functions as a channel.
US08367485B2 Embedded silicon germanium n-type filed effect transistor for reduced floating body effect
A method for fabricating a semiconductor device includes forming a gate stack on an active region of a silicon-on-insulator substrate. The active region is within a semiconductor layer and is doped with an p-type dopant. A gate spacer is formed surrounding the gate stack. A first trench is formed in a region reserved for a source region and a second trench is formed in a region reserved for a drain region. The first and second trenches are formed while maintaining exposed the region reserved for the source region and the region reserved for the drain region. Silicon germanium is epitaxially grown within the first trench and the second trench while maintaining exposed the regions reserved for the source and drain regions, respectively.
US08367484B2 Antifuse structure for in line circuit modification
An antifuse structure and methods of forming contacts within the antifuse structure. The antifuse structure includes a substrate having an overlying metal layer, a dielectric layer formed on an upper surface of the metal layer, and a contact formed of contact material within a contact via etched through the dielectric layer into the metal layer. The contact via includes a metal material at a bottom surface of the contact via and an untreated or partially treated metal precursor on top of the metal material.
US08367483B2 Antifuse structure for in line circuit modification
An antifuse structure and methods of forming contacts within the antifuse structure. The antifuse structure includes a substrate having an overlying metal layer, a dielectric layer formed on an upper surface of the metal layer, and a contact formed of contact material within a contact via etched through the dielectric layer into the metal layer. The contact via includes a metal material at a bottom surface of the contact via and an untreated or partially treated metal precursor on top of the metal material.
US08367480B2 Semiconductor device and method of forming dam material around periphery of die to reduce warpage
A semiconductor device has a carrier. A first semiconductor die is mounted to the carrier with an active surface of the first semiconductor die oriented toward the carrier. A dam structure is formed on the carrier and around the first semiconductor die by depositing dam material on the carrier with screen printing, electrolytic plating, electroless plating, or spray coating. An encapsulant is deposited over the carrier and around the first semiconductor die. The encapsulant has a coefficient of thermal expansion (CTE) that corresponds to a CTE of the dam material. The CTE of the dam material is equal to or less than the CTE of the encapsulant. The carrier is removed to expose the active surface of the first semiconductor die with the dam structure stiffening a periphery of the first semiconductor die. The semiconductor device is singulated through the dam structure.
US08367477B2 Electronic device package and method for forming the same
An embodiment of the invention provides a method for forming an electronic device package, which includes providing a carrier substrate having an upper surface and an opposite lower surface; forming a cavity from the upper surface of the carrier substrate; disposing an electronic device having a conducting electrode in the cavity; forming a filling layer in the cavity, wherein the filling layer surround the electronic device; thinning the carrier substrate from the lower surface to a predetermined thickness; forming at least a through-hole in the electronic device or the in the carrier substrate; and forming a conducting layer over a sidewall of the through-hole, wherein the conducting layer electrically connects to the conducting electrode.
US08367475B2 Chip scale package assembly in reconstitution panel process format
Methods, systems, and apparatuses are described for the assembly of integrated circuit (IC) packages. A substrate panel is formed that includes a plurality of substrates. The substrate panel is singulated to separate the plurality of substrates. At least a subset of the separated substrates is attached to a surface of a carrier. One or more dies are attached to each of the substrates on the carrier. The dies and the substrates are encapsulated on the carrier with a molding compound. The carrier is detached from the encapsulated dies and substrates to form a molded assembly that includes the molding compound encapsulating the dies and substrates. A plurality of interconnects is attached to each of the substrates at a surface of the molded assembly. The molded assembly is singulated to form a plurality of IC packages. Each IC package includes at least one of the dies and a substrate.
US08367473B2 Substrate having single patterned metal layer exposing patterned dielectric layer, chip package structure including the substrate, and manufacturing methods thereof
A chip package structure includes a substrate, a die, and a package body. The substrate includes a single patterned, electrically conductive layer, and a patterned dielectric layer adjacent to an upper surface of the electrically conductive layer. A part of a lower surface of the electrically conductive layer forms first contact pads for electrical connection externally. The patterned dielectric layer exposes a part of the upper surface of the electrically conductive layer to form second contact pads. The electrically conductive layer exposes the lower surface of the patterned dielectric layer on a lower periphery of the substrate. The die is electrically connected to the second contact pads, the patterned dielectric layer and the die being positioned on the same side of the electrically conductive layer. The package body is disposed adjacent to the upper surface of the electrically conductive layer and covers the patterned dielectric layer and the die.
US08367469B2 Chip-scale semiconductor die packaging method
A method of packaging one or more semiconductor dies is provided. The method includes: providing a first die having a circuit surface and a connecting surface; providing a chip-scale frame having an inside surface and an outside surface, the chip-scale frame having a well region having an opening in the inside surface; coupling the first die to a wall of the well region using a first coupling mechanism for electrical and mechanical coupling; providing a substrate having a top surface and a bottom surface; coupling the inside surface of the chip-scale frame with the top surface of the substrate by a second coupling mechanism, wherein a gap is provided between the circuit surface of the first die and the top surface of the substrate; coupling a heat sink to the outside surface of the chip-scale frame using a third coupling mechanism.
US08367467B2 Semiconductor method of forming bump on substrate to prevent ELK ILD delamination during reflow process
A method of making a semiconductor device that has a flipchip semiconductor die and substrate. A first insulating layer is formed over the substrate. A via is formed through the first insulating layer. Conductive material is deposited in the via to form a conductive pillar or stacked stud bumps. The conductive pillar is electrically connected to a conductive layer within the substrate. A second insulating layer is formed over the first insulating layer. Bump material is formed over the conductive pillar. The bump material is reflowed to form a bump. The first and second insulating layers are removed. The semiconductor die is mounted to the substrate by reflowing the bump to a conductive layer of the die. The semiconductor die also has a third insulating layer formed over the conductive layer and an active surface of the die and UBM formed over the first conductive layer and third insulating layer.
US08367459B2 Organic semiconductor interface preparation
A method is provided for preparing an interface surface for the deposition of an organic semiconductor material, in the fabrication of an organic thin film transistor (OTFT). A substrate is provided and a gate electrode is formed overlying the substrate. A gate dielectric is formed overlying the gate electrode. Then, source (S) and drain (D) electrodes are formed overlying the gate dielectric, exposing a gate dielectric channel interface region between the S/D electrodes. Subsequent to exposing the OTFT to a H2 or N2 plasma, a self-assembled organic monolayer is formed overlying the S/D electrodes. Finally, an active organic semiconductor layer is formed over the S/D electrodes and gate dielectric channel interface. The OTFT may be exposed to plasma either before or after the formation of the S/D electrodes.
US08367458B2 Method for production of an organic light emitting diode or of an organic solar cell and organic light emitting diodes or solar cells produced therewith
The present invention relates to a process for producing an electronic device having two contacts, an anode and a cathode being completely or partly transmissive to light, one or more organic semi-conducting layers and one or more organic buffer layers between the contacts or the cathode and anode respectively. A solution is sprayed which contains organic material for applying at least one porous layer.
US08367448B2 Capacitor and organic light emitting display device
A capacitor of an organic light emitting display device includes a first metal layer on a substrate, a first insulating layer on the first metal layer, an oxide semiconductor layer on the first insulating layer, the oxide semiconductor layer corresponding to the first metal layer, a second insulating layer on the first insulating layer, the second insulating layer including an opening exposing a portion of the oxide semiconductor layer, and a second metal layer on the second insulating layer and in the opening, the second metal layer being connected to the exposed portion of the oxide semiconductor layer.
US08367445B2 Group III nitride semiconductor light-emitting device
A method for producing a Group III nitride semiconductor light-emitting device includes forming a first stripe-pattern embossment on the top surface of a sapphire substrate, so that first grooves parallel to the x-axis direction (the c-axis direction of the sapphire substrate) are periodically arranged at specific intervals. Subsequently, an insulating film is formed over the entire surface of the first stripe-pattern embossment. Next, a second stripe-pattern embossment is formed so that second grooves, each having a flat bottom surface, are periodically arranged at specific intervals and parallel to the y-axis direction, which is orthogonal to the x-axis direction. A GaN crystal is grown through MOCVD on side surfaces of each second groove of the sapphire substrate, to thereby form, on the sapphire substrate, an m-plane GaN base layer. An LED device structure is formed on the base layer, to thereby produce a light-emitting device.
US08367443B2 Method of manufacturing semiconductor light emitting device
Provided is a method of manufacturing semiconductor light emitting devices including: forming light emitting structures by sequentially depositing a first material layer, an active layer and a second material layer; forming the roughness pattern on a region of the bottom of a substrate except at least a cleaving region for forming cleaving planes; and forming n-electrodes.
US08367437B2 Method of manufacturing light-emitting device
A method of manufacturing a light-emitting device includes arranging a plate-shaped glass on a light-emitting element mounting surface of a substrate having a light-emitting element mounted thereon, arranging a metal thin plate on the plate-shaped glass so as to sandwich the plate-shaped glass between the substrate and the metal thin plate, placing the substrate, the plate-shaped glass and the metal thin plate between a first mold on a side of the substrate and a second mold on a side of the metal thin plate, hot-pressing the substrate, the plate-shaped glass and the metal thin plate by using the first mold and the second mold to seal the light-emitting element with the plate-shaped glass, and after cooling the plate-shaped glass, removing the thin plate adhered to the plate-shaped glass from the plate-shaped glass.
US08367436B2 Organic light emitting diode display and manufacturing method therefor
A manufacturing method of an organic light emitting diode (OLED) display device includes forming a thin film transistor and an organic light emitting diode in a display area of a first substrate, forming a thin film encapsulation layer that has a layering structure of an organic film and an inorganic film on one substrate of the first substrate and a second substrate, forming a sealing member by coating a sealing material that includes an inorganic sealant and an organic compound on an edge of the second substrate, removing the organic compound of the sealing member by baking the sealing member, layering the second substrate on the first substrate so that the sealing member contacts the first substrate, dissolving the sealing member by using a laser beam, solidifying the sealing member, attaching the sealing member to the first substrate, and removing the second substrate from the sealing member.
US08367433B2 Fabrication method of semiconductor device
A technique is provided which can exactly recognize a chip to be picked up when picking up the chip from a wafer sheet in a process of die bonding a thin chip. A camera is coupled to one end of a lens barrel, an objective lens is attached to an opposite end of the lens barrel, and an image of a main surface of a chip is photographed through the objective lens. A surface-emitting lighting unit, a diffusing plate and a half mirror are internally provided between the lens barrel and the chip. Further, another lens barrel having a coaxial drop lighting function of radiating light to the main surface of the chip along the same optical axis as that of the camera is disposed.
US08367427B2 Methods of processing compositions containing microparticles
A method for processing multi-phasic dispersions is provided. The method comprises providing a multi-phasic dispersion including dispersed and continuous phases, providing one or more non-solvents comprising an aqueous solution containing at least one multivalent cation, exposing the multi-phasic dispersion to the non-solvent to form a suspension containing one or more liquid phases and the solid microparticles, and removing at least a portion of the resulting one or more liquid phases while retaining at least the microparticles, thereby removing at least a portion of the non-volatile material from the microparticles.
US08367422B2 Biochemical analyzer and method of controlling internal temperature of the biochemical analyzer
Provided is a biochemical analyzer including: a microfluidic device loading space including a microfluidic device supporting unit detachably supporting a microfluidic device including an electromagnetic radiation application region in which electromagnetic energy is applied; an energy source loading space including an energy source applying the electromagnetic energy to the electromagnetic radiation application region; and an isolation wall isolating the microfluidic device loading space and the energy source loading space to prevent heat transfer between the microfluidic device loading space and the energy source loading space and including a transparent window through which the electromagnetic energy can be transmitted. A method of controlling an internal temperature of the biochemical analyzer is also provided.
US08367420B1 Method and system for detecting sulfur in soil from reflected light
The present invention relates to a method of detecting soil nutrients or soil nutrients in soil from reflected light, and also includes systems for the measurement, calculation and transmission of data relating to or carrying out that method.
US08367418B2 Method and system to provide personalized pharmaceutical compositions and dosages
The invention provides a method for determining a suitable drug combination for the treatment of Type 2 diabetes by obtaining data from a Type 2 diabetes population in which all of the Type 2 diabetics are not taking any Type-2 diabetes drugs and obtaining reference levels of glucose supply and insulin demand parameters. Data from discrete samples of Type 2 diabetes populations in which all individuals are being treated with one or more Type 2 diabetes drugs at a therapeutic dose are also obtained, and the effects of the drugs on the glucose supply and insulin demand parameters are used to determine adjustment factors which represent the effect of each of the drugs at the therapeutic dosage, which are used to determined a ratio of a Glucose Supply Index (S) to an Insulin Demand Index (D). The ratio is further utilized in scoring cardiovascular risks for Type 2 diabetics and recommending therapeutic interventions.
US08367410B2 Application of electrical stimulation for functional tissue engineering in vitro and in vivo
The present invention provides new methods for the in vitro preparation of bioartificial tissue equivalents and their enhanced integration after implantation in vivo. These methods include submitting a tissue construct to a biomimetic electrical stimulation during cultivation in vitro to improve its structural and functional properties, and/or in vivo, after implantation of the construct, to enhance its integration with host tissue and increase cell survival and functionality. The inventive methods are particularly useful for the production of bioartificial equivalents and/or the repair and replacement of native tissues that contain electrically excitable cells and are subject to electrical stimulation in vivo, such as, for example, cardiac muscle tissue, striated skeletal muscle tissue, smooth muscle tissue, bone, vasculature, and nerve tissue.
US08367408B2 Fusion partner for production of monoclonal rabbit antibodies
The invention provides a rabbit-derived immortal B-lymphocyte capable of fusion with a rabbit splenocyte to produce a hybrid cell that produces an antibody. The immortal B-lymphocyte does not detectably express endogenous immunoglobulin heavy chain and may contain, in certain embodiments, an altered immunoglobulin heavy chain-encoding gene. A hybridoma resulting from fusion between the subject immortal B-lymphocyte and a rabbit antibody-producing cell is provided, as is a method of using that hybridoma to produce an antibody. The subject invention finds use in a variety of different diagnostic, therapeutic and research applications.
US08367406B2 Pluripotent cells
Pluripotent cells that are immunopositive for both the neural progenitor marker nestin and a pluripotent cell marker are provided. The cells exhibit rapid doubling times and can be maintained in vitro for extended periods. Also provided are cell cultures containing the pluripotent cells, a method of transplanting human pluripotent cells to a host, and a method of reducing seizure activity in a subject. These pluripotent cells, when transplanted into the ventricle of a host animal, migrate to the site of damage and adopt a suitably corrective phenotype, resulting in both structural and functional restoration.
US08367404B2 Chimeral internal ribosomal entry site sequence and uses thereof
An improved baculovirus vector capable of expressing genes in mammalian or insect host cells, and the uses thereof are disclosed. The improved baculovirus vector includes in sequence: a promoter; a first nucleic acid operably linked to the promoter for expressing a first protein in the mammalian or insect host cells; a chimera internal ribosomal entry site (IRES) comprising a portion of an enterovirus (EV) IRES sequence at least 90% identical to SEQ ID NO: 1 and a portion of a Rhopalosiphum padi virus (RhPV) IRES sequence at least 90% identical to SEQ ID NO: 2; and a second nucleic acid operable linked to the portion of the RhPV IRES sequence for expressing a second protein in the mammalian or insect host cells.
US08367401B2 Replication competent hepatitis C virus and methods of use
The present invention provides a replication competent hepatitis C virus that includes a heterologous polynucleotide. The invention also includes methods for modifying a hepatitis C virus polynucleotide, selecting a replication competent hepatitis C virus polynucleotide, detecting a replication competent hepatitis C virus polynucleotide, and identifying a compound that inhibits replication of a hepatitis C virus polynucleotide.
US08367400B2 Culture vessel allowing large in situ scale up
The present invention, in one aspect, provides a culture vessel which includes a body having at least a first edge at least partially perimetrically bounding the body, and at least a first seal extending from the first edge. The first seal is breachable and fluid-tight, and disposed obliquely to the first edge so as to subtend an acute angle therewith. The first seal separates the body into first and second chambers. Advantageously, with the subject invention, a culture vessel is provided which allows for volume expansion in situ.
US08367397B2 Active biochip for nucleic acid analysis
Embodiments of the invention relate to an active biochip for nucleic acid analysis. The biochip comprises an inlet for introducing a nucleic acid sample, fluid channels, valves in contact with the fluid channels and pumps in contact with the fluid channels and adapted to generate a carrier gas or move a buffer through a portion of the fluid channels. The biochip also includes one or more hydroxyapatite columns for separating a portion of the nucleic acid sample, buffer reservoirs in contact with the fluid channels and positioned near the pumps, air exits, a waste reservoir and a nucleic acid analysis region.
US08367394B2 Process for the synthesis of 9α-hydroxy-steroids
The present invention relates to a novel selective synthesis of 9α-hydroxy-steroid derivatives of the general formula (I) (I)—wherein the meaning of -A-A′- is —CH2—CH2— or —CH═CH— group—by the bioconversion of compounds of the general formula (II) (II) wherein the meaning of -A-A′- is —CH2—CH2— or —CH═CH— group—by using Nocardia farcinica bacterium strain, deposition number of which is NCAIM (P)—B 001342, as hydroxylating microorganism in the bioconversion.
US08367393B2 Saccharomyces strain with ability to grow on pentose sugars under anaerobic cultivation conditions
The invention relates to an improved Saccharomyces strain displaying improved viability and growth during anaerobic fermentation of pentose carbon sources such as xylose and producing fermentation products such as ethanol.
US08367391B2 Method for detecting or determining abnormal prion protein associated with transmissible spongiform encephalopathy in blood-derived specimen or body fluid-derived specimen
A pretreatment method of a specimen used for detecting or determining abnormal prion protein (PrPres) associated with transmissible spongiform encephalopathy (TSE), wherein (1) a specimen which had been treated with proteinase K is heated in the presence of sodium dodecyl sulfate (SDS) to dissolve proteins and inactivate infectious activity in the specimen at the same time; (2) the specimen processed in the above (1) is cooled under a neutral condition to make abnormal prion protein (PrPres) associated with transmissible spongiform encephalopathy (TSE) aggregated; (3) the aggregate formed in the above (2) is separated from a solution; and (4) the separated PrPres aggregate is detected by the ultrasensitive chemiluminescence method.
US08367390B2 Galactanase variants
The present invention relates to variants of Glycoside Hydrolase family 53 galactanases, e.g., variants of the galactanases from strains of Yersinia, Aspergillus, Humicola, Meripilus, Myceliophthora, Thermomyces, Bacillus, Bifidobacterium, Cellvibrio, Clostridium, Pseudomonas, Thermotoga, or Xanthomonas.
US08367387B2 Fungal peroxygenases and methods of application
The invention relates to polypeptides having peroxygenase activity and compositions comprising such polypeptides, their encoding polynucleotides, expression vectors and recombinant host cells comprising such polynucleotides or vectors, methods of producing the polypeptides, as well as methods of application and uses thereof, including a process for enzymatic, regioselective oxygenation of N-heterocycles of the general formula (I) to the corresponding N-oxides of the formula (II), by converting N-heterocycles of the formula (I) with a peroxidase polypeptide in the presence of at least one oxidizing agent in a one-stage reaction process.
US08367383B2 Mutant Δ-5 desaturases mutated in the heme-binding motif (HPGG) and their use in making polyunsaturated fatty acids
The present invention relates to mutant Δ5 desaturases, which have the ability to convert dihomo-γ-linolenic acid [DGLA; 20:3 ω-6] to arachidonic acid [ARA; 20:4 ω-6] and/or eicosatetraenoic acid [ETA; 20:4 ω-3] to eicosapentaenoic acid [EPA; 20:5 ω-3] and which possess at least one mutation within the HPGG motif of the cytochome b5-like domain. Isolated nucleic acid fragments and recombinant constructs comprising such fragments encoding Δ5 desaturases, along with a method of making long chain polyunsaturated fatty acids [“PUFAs”] using these mutant Δ5 desaturases in oleaginous yeast, are disclosed.
US08367377B2 Methods and devices for nucleic acid sequence determination
Methods of the invention comprise methods and devices for nucleic acid sequence determination. Generally, the invention relates to preparing a substrate for sequencing a target nucleic acid.
US08367376B2 Compositions with polymerase activity
The invention provides novel compositions with polymerase activity and methods of using the compositions.
US08367369B2 Method and apparatus for detecting phycocyanin-pigmented algae and bacteria from reflected light
The present invention relates to a method of detecting phycocyanin algae or bacteria in water from reflected light, and also includes devices for the measurement, calculation and transmission of data relating to that method.
US08367368B2 D-serine dehydratase and use thereof
A novel D-serine quantification method that can overcome various disadvantages of a conventional D-serine quantification method; a novel enzyme that can be used in the D-serine quantification method; a gene encoding the enzyme; and the like. Specifically, a novel D-serine dehydratase including (a) a protein having an amino acid sequence set forth in SEQ ID NO: 1 or (b) a protein having an amino acid sequence homologous to the amino acid sequence set forth in SEQ ID NO: 1 and having a D-serine dehydratase activity; and a D-serine quantification method including the steps of reacting a sample with the enzyme, quantifying ammonia or pyruvic acid produced by the reaction, and calculating the amount of D-serine in the sample based on a value produced by the quantification.
US08367364B2 Methods of screening an agent for an activity in an isolated eye of a teleost
The present invention provides methods of screening an agent for an activity in an isolated organ, e.g., eye, from a teleost, e.g., zebrafish. Methods of isolating eyes from zebrafish are provided. Methods of screening an agent for an ocular activity in the isolated eye are provided. Methods of screening an agent for an ocular activity in a model of ocular disease or disorder are provided. Methods of screening an agent for an ocular activity in the isolated eye and for screening the agent for cell death and/or toxic activity in the eye or other organ or tissue are provided. The invention further provides high throughput methods of screening agents for an activity in isolated eyes of zebrafish in multi-well plates.
US08367363B2 Method of determining the probability of a therapeutic response in cancer chemotherapy with cardiac glycoside
A prognostic assay and kit and method of use thereof are provided. The kit and assay are used to determine the likelihood of a diseased cell or tissue having a therapeutic response to treatment with a cardiac glycoside in a disease having an etiology associated with excessive cell proliferation. The kit and assay are used to determine the ratio of isoforms of the α subunit of Na, K-ATPase obtained from the diseased cell or tissue. The kit can be used to predict the therapeutic responsiveness of cancer or tumor in a subject to treatment with a cardiac glycoside. The kit and assay can be incorporated in a method of treating a disease or disorder having an etiology associated with excessive cell proliferation with a composition comprising a cardiac glycoside.
US08367360B2 Method of screening for inhibitors of tau protein phosphororylation by tyrosine kinase c-Abl
The present invention provides methods of screening for candidate compounds useful in the treatment of Alzheimer's disease and related conditions by inhibiting specific phosphorylation of tau protein by tyrosine kinase c-Abl.
US08367359B1 Metabolic biomarkers for diabetes and insulin resistance
Disclosed are small molecule metabolites useful as biomarkers for the evaluation and treatment of pre diabetes, diabetes and insulin resistance.
US08367357B2 Two secretory luciferases
The present invention is one gene construct or a combination of two gene constructs or expression vectors incorporating a Cypridina luciferase gene and a copepod luciferase under the control of distinct promoters. These gene constructs and expression vectors are useful for making a mammalian cell incorporating the Cypridina luciferase gene and the copepod luciferase to be capable of stably expressed and extracellularly secreted under the control of the distinct promoters.
US08367355B2 Method of quantitative assessment on reproductive effort of black-lip pearl oysters using antibody specific thereto
Disclosed are an antigen protein of black-lip pearl oyster egg extract, an antibody specific thereto, and a method of quantitative assessment of the reproductive effort of black-lip pearl oyster using the antibody. The method accomplishes quantitative assessment of reproductive effort of black-lip pearl oysters easily and accurately. In addition, the method provides important information for the study of life cycles of black-lip pearl oysters, and allows efficient management of black-lip pearl oysters.
US08367353B2 Method for improved diagnosis of dysplasias
The present invention relates to a method for improved diagnosis of dysplasias based on simultaneous detection of INK4a gene products and at least one marker for cell proliferation. Particularly the present invention provides a method for discriminating dysplastic cells over-expressing INK4a gene products from cells over-expressing INK4a gene products without being dysplastic by detection of a marker suitable for characterizing the proliferation properties of the respective cell. The characterization of the proliferation properties may comprise the detection of a marker or a set of markers characteristic for active cell proliferation and/or a marker or a set of markers characteristic for retarded or ceased cell proliferation. The method presented herein thus enables for a specific diagnosis of dysplasias in histological and cytological specimens.
US08367352B2 Promoting axon regeneration in the adult CNS through control of protein translation
Survival of, or axon regeneration in a lesioned mature central nervous system (CNS) neuron is promoted by (a) contacting the neuron with a therapeutically effective amount of an exogenous activator of protein translation; and (b) detecting the resultant promotion of the survival of, or axon regeneration in the neuron.
US08367349B2 Methods for identifying modulators of LRRK2
A method for assessing the effect of a test compound on LRRK2 in a cell-based system, the method comprising the steps of a) assessing the effect of exposing the cell-based system comprising LRRK2 to the test compound on the phosphorylation state of Ser910 and/or Ser935 of the LRRK2; and/or b) assessing the effect of exposing the cell-based system comprising LRRK2 to the test compound on the binding of the LRRK2 to a 14-3-3 polypeptide. The method may comprise or further comprise the step of assessing the effect of exposing the cell-based system comprising LRRK2 to the test compound on the subcellular location of LRRK2. The method is considered to be useful in assessing the effect of putative LRRK2 inhibitors in cell based systems, including in vivo systems.
US08367340B2 Prognostic tools to predict the efficacy of drug treatment targeting chromatin DNA or enzymes acting on DNA
Disclosed are methods of predicting cell response to drug-based therapy using both PCR-Stop assays and real time PCR assays. Methods herein may be used for assessment of drug effect, evaluation of regimen suitability for a given patient, and/or for determination of an optimal drug dose. Also provided are isolated oligonucleotide primers such as primers capable of annealing under PCR conditions to a segment of a c-myc locus, where the primers may be used in the disclosed methods. Further disclosed are kits and systems that may be used for predicting a cell response to drug-based therapy.
US08367337B2 Detection of methicillin-resistant Staphylococcus aureus
The present invention provides improved tests for the detection of methicillin-resistant Staphylococcus aureus. The tests are particularly useful for eliminating false positive results due to the presence of a mixed bacterial population in patient samples.
US08367335B2 Programmable oligonucleotide synthesis
The invention relates to methods and devices for preparing synthetic nucleic acids.
US08367332B2 Detection and quantification of abasic site formation in vivo
A method of measuring the efficacy of an anticancer agent in generating abasic (AP) sites in DNA of cancer cells of a subject includes administering to the subject an anticancer agent that generates AP sites in at least one cancer cell and an AP endonuclease inhibitor probe. The AP endonuclease inhibitor probe includes a detection moiety for detecting the probe in the subject. The amount of probe bound to cancer cells of the subject is then measured. The amount of probe bound to cancer cells of the subject is indicative of efficacy of the anticancer agent in generating AP sites in cancer cells of the subject.
US08367325B2 Late-PCR
A non-symmetric polymerise chain reaction (PCR) amplification method employing a limiting primer in low concentration whose concentration-adjusted melting point at least equals, and preferably exceeds, that of the excess primer, the latter in turn not being more than 25° C. below the melting temperature of the amplicon. Assays employing such amplification and labeled hybridization probes, including assays that include a detection step following primer extension or a low-temperature probe, or both. Kits for performing such assays and primer or primer-and-probe sets for performing the foregoing amplifications and assays.
US08367324B2 Method for judging change in probe-bearing substrate, probe-bearing substrate and detecting apparatus
A probe-bearing substrate in which a probe capable of specifically binding to a target substance is immobilized on a substrate, characterized in that the probe-bearing substrate further includes a device for detecting an environmental change that may cause a change in the probe-bearing substrate such as probe deterioration or change in a substrate-protecting member.
US08367317B2 Variants of hepatitis B virus with resistance to anti-viral nucleoside agents and applications thereof
The present invention relates generally to viral variants exhibiting reduced sensitivity to particular agents and/or reduced interactivity with immunological reagents. More particularly, the present invention is directed to hepatitis B virus (HBV) variants exhibiting complete or partial resistance to nucleoside or nucleotide analogs and/or reduced interactivity with antibodies to viral surface components including reduced sensitivity to these antibodies. The present invention further contemplates assays for detecting such viral variants, which assays are useful in monitoring anti-viral therapeutic regimens and in developing new or modified vaccines directed against viral agents and in particular HBV variants. The present invention also contemplates the use of the viral variants to screen for and/or develop or design agents capable of inhibiting infection, replication and/or release of the virus.
US08367316B2 Human gastrointestinal stem cell-derived primary intestinal epithelial cell system and methods of use thereof
The present invention relates to an intestinal primary epithelial cell system for detecting gastrointestinal segment-specific activation or suppression of a Toll-like receptor (TLR) by a target agent. The cell system includes an isolated human intestinal primary epithelial cell (HIPEC) line that expresses at least one TLR, where the HIPEC line is derived from a differentiable adult human gastrointestinal stem cell (ahGISC) line. Also disclosed are various methods of using the cell system, a kit that includes the cell system, and an isolated cell culture including an isolated HIPEC line derived from a differentiable ahGISC line.
US08367313B2 Method of determining sperm capacitation
This invention describes unique patterns of distribution of ganglioside GM1 in non-capacitated sperm and demonstrates that the pattern of distribution of GM1 undergoes changes that can be correlated with the process of capacitation and/or with acrosomal exocytosis. Accordingly, the present invention discloses a method for determining the ability of sperm to respond to capacitation and/or acrosomal exocytosis stimuli. The method comprises determination of distribution pattern for GM1. The method can be used for both diagnostic and predictive purposes when assessing male reproductive fitness, and can also be used to assess the effects of any agent or environment on sperm including cryoprotective agents and protocols, and contraceptive agents.
US08367308B2 Substrate processing method
A substrate processing method includes a first process (step S12 to step S16) of forming a first resist pattern by exposing a substrate having thereon a first resist film to lights, developing the exposed substrate and cleaning the developed substrate; and a second process (step S17 to step S20) of forming a second resist pattern by forming a second resist film on the substrate having thereon the first resist pattern, exposing the substrate having thereon the second resist film to lights, and developing the exposed substrate. A first processing condition is determined based on first data showing a relationship between a first processing condition under which a cleaning process is performed on the substrate in the first process (step S16) and a line width of the second resist pattern, and the first process (step S16) is performed on the substrate under the determined first processing condition.
US08367304B2 Techniques for marking product housings
Techniques or processes for providing markings on products are disclosed. The markings provided on products can be textual and/or graphic. The techniques or processes can provide high resolution markings on surfaces that are flat or curved. In one embodiment, the products have housings and the markings are to be provided on the housings. For example, the housing for a particular product can include an outer housing surface and the markings can be provided on the outer housing surface.
US08367302B2 Method and apparatus for manufacturing semiconductor device
A method and apparatus for manufacturing a semiconductor device is disclosed. In particular, the application discloses a method that performs a lithography process using a material capable of increasing a depth of focus so as to prevent efficiency of the lithography process from being degraded due to high integration of a semiconductor device, and a pressure-type bake oven as an apparatus for forming a high refractive material on a semiconductor substrate, having advantages of reducing manufacturing costs of a semiconductor manufacturing process and increasing efficiency of the lithography process.
US08367298B2 Salt and photoresist composition containing the same
A salt having a divalent group represented by the formula (aa): wherein Xa and Xb independently each represent —O— or —S—, Ra, Rb, Rc and Rd independently each represent a hydrogen atom, a C1-C4 alkyl group or a C1-C4 alkoxy group, and m represents 1 or 2.
US08367294B2 Toner process
The present disclosure provides processes for preparing toner particles, in which fewer coarse particles are generated. The process includes introducing a buffer solution during coalescence of the toner slurry. The amount of coarse particles in the resulting toner particles may, in embodiments, be reduced to less than about 5 percent by weight of the total toner particles generated.
US08367292B2 Toner and development agent
A toner including a binder resin, a coloring agent, and a releasing agent, the toner formed by dispersing a toner liquid material which is prepared by dispersing the binder resin, the prepolymer, an elongation agent and/or a cross-linking agent for the prepolymer, the coloring agent, and the releasing agent in an organic solvent, dispersing the toner liquid material in an aqueous medium to obtain a liquid dispersion in at least one of cross linking reaction and elongation reaction, and removing the organic solvent from the liquid dispersion, and the toner satisfying the following relationship: 1.35< or =M(g)/M(p)< or =1.90, where M(g) represents the content of the gel composition formed in the at least one of cross linking reaction and elongation reaction and M(P) represents the content of the prepolymer in the toner liquid material when the total of M(P) and the content of the binder resin in the toner liquid material is set to be 100 g.
US08367289B2 Toner
A toner is provided which is excellent in development stability in both a low-temperature, low-humidity environment and a high-temperature, high-humidity environment over a long time period. The toner includes toner particles containing at least a binder resin and a colorant, and a fatty acid metal salt. The fatty acid metal salt has a volume-based median diameter (D50s) of 0.15 μm or more and 0.65 μm or less, and the liberation ratio of the fatty acid metal salt in the toner is 1.0% or more and 25.0% or less.
US08367287B2 Electrophotographic photoconductor, method of producing the same and image forming apparatus
An electrophotographic photoconductor of the invention comprising: an conductive support; a light-sensitive layer formed on the conductive support and containing a charge generating material and a charge transport material; and a surface protective layer formed on the light-sensitive layer and made of a resin composition, wherein the resin composition constituting the surface protective layer contains an amine compound represented by the following formula (1): wherein R1 and R2 are, the same or different, each an alkyl group or an allyl group which may have a substituent or a heterocyclic residue to be formed through or not through a nitrogen atom or an oxygen atom together with the nitrogen atom to which R1 and R2 are bonded, R3 and R4 are, the same or different, each an alkyl group having a substituent and n denotes 1 or 2, provided that when n is 1, X is a hydrogen atom, a halogen atom, or an alkyl group, a hydroxyl group or a mercapto group which may have a substituent, or a ring optionally containing an oxygen atom and a nitrogen atom between carbon atoms and when n is 2, X is an oxygen atom or a sulfur atom.
US08367283B2 Positive photosensitive resin composition, cured film, protecting film, insulating film and semiconductor and display devices using the same
The positive photosensitive resin composition of the present invention has a polyamide resin and a photosensitive agent, wherein the polyamide resin has a specific structure. The cured film of the present invention has a cured product of the positive photosensitive resin composition. The protecting film and insulating film of the present invention has the cured film each. The semiconductor device and display device of the present invention has the cured film each.
US08367264B2 Fuel cell system with co detector
A fuel cell system of the present invention includes: a hydrogen generator (1) having a reformer (1a) configured to generate a hydrogen-containing gas by a reforming reaction using a raw material; a fuel cell (2) configured to generate electric power using the hydrogen-containing gas supplied from the hydrogen generator (1); a combustor (3) configured to combust an anode off gas discharged from the fuel cell (2) to heat the reformer (1a); a CO detector (7) configured to detect a carbon monoxide concentration of a flue gas discharged from the combustor (3); an electric heater (8) configured to heat the CO detector (7); and a controller (19), and the controller (19) is configured to increase an amount of energization to the electric heater (8) in accordance with an increase in an amount of electric power generated by the fuel cell (2).
US08367258B2 Electric power source arrangement and method of how to use it
An electric power source arrangement is described, comprising a fuel cell means (2) having a nominal voltage and a specified voltage-current characteristic, to be connected to a load (1), and comprising a variable DC-DC voltage converter (3), a by-pass branch (11) by-passing the DC-DC voltage converter, a switch (13) alternatively connecting the fuel cell to the DC-DC voltage converter or to the by-pass branch, and a control unit (12) controlling the switch, which control unit (12) comprises a measuring device coupled to the fuel cell means (2) for detecting the operating point thereof and is configured to connect the by-pass branch (11) if the fuel cell means voltage is within a selected range of section (5) of the voltage-current characteristic of the fuel cell means and to disconnect the by-pass branch in the remaining range of sections (4, 6, 7) of said characteristic.
US08367257B2 Fuel cell system and method for adjusting moisture content in a polymer electrolyte membrane
A fuel cell system (10) that includes with a polymer electrolyte fuel cell (22) having a polymer electrolyte membrane is provided with a determining portion that determines whether a moisture content in the polymer electrolyte membrane is low, and an anode gas pressure regulating portion that sets a gas pressure on an anode side of the fuel cell lower than a set value of the gas pressure on the anode side during steady operation in which the moisture content is not low, when it is determined that the moisture content is low.
US08367256B2 Water recovery assembly for use in high temperature fuel cell systems
A water recovery assembly for use in a fuel cell system having an anode and a cathode, the anode being adapted to receive fuel and output anode exhaust, the water recovery assembly comprising a first cooling assembly adapted to receive and quench cool the anode exhaust and to recover a first portion of water including electrolyte from the anode exhaust, and to output quenched anode exhaust and the first portion of water, and a second cooling assembly adapted to receive the quenched anode exhaust and to recover a second portion of water from the quenched anode exhaust, the second portion of water being suitable for humidifying the fuel supplied to the anode.
US08367254B2 Electrolyte for a high voltage battery and lithium secondary battery comprising the same
The present invention provides an electrolyte for lithium secondary batteries that allows the batteries to operate safely at a charging voltage up to 4.35V, wherein the electrolyte comprises a combination of a fluoroethylene carbonate compound and a linear ester compound as solvent. Also, the present invention provides a lithium secondary battery that can operate at a charging voltage up to 4.35V, which comprises a positive electrode, a negative electrode and an electrolyte, wherein the electrolyte comprises fluoroethylene carbonate compound and linear ester compound as solvent.
US08367253B2 Lithium-ion batteries with intrinsic pulse overcharge protection
The present invention relates in general to the field of lithium rechargeable batteries, and more particularly relates to the positive electrode design of lithium-ion batteries with improved high-rate pulse overcharge protection. Thus the present invention provides electrochemical devices containing a cathode comprising at least one primary positive material and at least one secondary positive material; an anode; and a non-aqueous electrolyte comprising a redox shuttle additive; wherein the redox potential of the redox shuttle additive is greater than the redox potential of the primary positive material; the redox potential of the redox shuttle additive is lower than the redox potential of the secondary positive material; and the redox shuttle additive is stable at least up to the redox potential of the secondary positive material.
US08367252B2 Non-aqueous electrolyte secondary battery
A non-aqueous electrolyte secondary battery wherein the non-aqueous electrolyte contains a non-aqueous solvent, a solute dissolved in the non-aqueous solvent, and hydrogenated terphenyl, the solute includes a boron-containing alkali salt and a boron-free alkali salt, the negative electrode includes a negative electrode active material comprising a randomly oriented carbon composite (A), and the carbon composite (A) contains a graphitic carbon substance (B) and a carbon substance (C) that is different from the graphitic carbon substance (B).
US08367251B2 Anode with lithium containing ionic polymer coat, method of manufacturing same, secondary battery, and method of manufacturing same
A secondary battery capable of improving the cycle characteristics is provided. The secondary battery includes a cathode, an anode, and an electrolytic solution. The anode has an anode current collector, an anode active material layer that is provided on the anode current collector, and contains an anode active material containing at least one of a simple substance of silicon, an alloy of silicon, a compound of silicon, a simple substance of tin, an alloy of tin, and a compound of tin, and a coat that is provided on the anode active material layer, and contains an ionic polymer containing lithium.
US08367250B2 Device for storing electric power comprising a protective barrier layer for the collector
The invention concerns a device for storing electric power and method for assembling the device. The device includes an electrode layer and a collector layer associated with the electrode layer, a barrier layer made of metal nitride, the barrier layer being interposed between the electrode layer and the collector layer. The barrier layer is adapted to prevent diffusion of ions contained in an electrolyte up to the collector layer.
US08367246B2 High-power battery
A method of forming battery electrodes with high specific surface and thin layers of active material is disclosed. The method enables low series resistance and high battery power.
US08367242B2 Rechargeable battery
A rechargeable battery including an electrode assembly, the electrode assembly including a separator interposed between a first electrode and a second electrode; a case, the case accommodating the electrode assembly; a cap plate, the cap plate sealing an opening at one end of the case; and electrode terminals, the electrode terminals being electrically connected to the electrode assembly, wherein at least one of the electrode terminals is integrally formed with the cap plate.
US08367241B2 Separator for fuel cell and manufacturing method therefor
Disclosed are a separator for a fuel cell realizing both the high electrical conductivity and the corrosion resistance and enabling using stably for a long period of time in the fuel cell and a manufacturing method for it. The separator for a fuel cell 1 includes a substrate 2 composed of pure aluminum or aluminum alloy and a plating layer 3 formed on the substrate 2, wherein the plating layer 3 has a copper layer 3a formed in the substrate 2 side and a tin layer 3b formed on the copper layer 3a, the tin layer 3b is formed in an uppermost layer, the thickness of the copper layer 3a is 0.10 μm or above, and the value obtained by dividing the thickness of the tin layer 3b by the thickness of the copper layer 3a is 0.1-50.
US08367240B2 Lithium secondary battery with wound electrodes
A battery comprising a first electrode, a second electrode, a separator interposed between the first electrode and the second electrode, and an electrolyte having lithium ion conductivity. The first electrode and the second electrode are wound with the separator interposed therebetween to form an electrode assembly. The first electrode includes a current collector and an active material layer carried on one face of the current collector. The active material layer includes columnar particles having a bottom and a head, the bottom of the columnar particles being adhered to the current collector. The head of the columnar particles is positioned at an outer round side of the electrode assembly than the bottom.
US08367238B2 Mounting apparatus for battery module
A mounting apparatus for a battery module includes a base, a latching member slidably attached to the base to fix the battery module, and an operating member rotatably attached to the base. When the operating member of the mounting apparatus is rotated, the latching member is driven to slide to disengage from the battery module.
US08367232B2 Venting system for an underground enclosure
A pressurized underground enclosure includes a battery venting system having a battery within a battery box in a sealed enclosure. A first pipe is fluidly connected to the battery box and an ambient atmosphere and includes a vacuum generator for reducing a pressure in the battery box. A second pipe is fluidly connected to the battery box and the ambient atmosphere and includes a one-way valve permitting airflow to the battery box and precluding airflow from the battery box to the ambient atmosphere. The enclosure includes a scissors lift including scissor linkage units having arms pivotally connected at terminal ends and at central positions. The scissor linkage units are moveable from a retracted to an extended position by pneumatic cylinders. The internal pressurization of the enclosure is selectively released and locking mechanisms are retracted before a rack of the scissors lift is extended through an opening of the enclosure.
US08367228B2 Magnetic recording medium having patterned auxiliary recording layer and method for manufacturing such magnetic recording medium
A method for manufacturing a magnetic recording medium for perpendicular magnetic recording includes the steps of forming a first magnetic layer which has magnetic crystal grains exhibiting perpendicular magnetic anisotropy and nonmagnetic substances for magnetically separating the magnetic crystal grains from each other at grain boundaries of the magnetic crystal grains, forming a second magnetic layer which has magnetic grains exchange-coupled to the magnetic crystal grains, a grain boundary width of the magnetic grains being smaller than a grain boundary width of the magnetic crystal grains, and forming separation regions which magnetically separate tracks from each other in regions between the tracks of the magnetic recording medium in at least the second magnetic layer. The separation regions are disposed substantially only in the second magnetic layer of the first magnetic layer and the second magnetic layer.
US08367221B2 Organic light emitting device with cathode interface modification layer and fabrication method thereof
The present invention provides an organic light emitting device and a fabrication method thereof, comprising a substrate, an anode layer formed on said substrate, an organic function layer formed on said anode layer, and a cathode layer formed on said organic function layer, characterized in that, further comprising a cathode interface modification layer between said organic function layer and said cathode layer, wherein said cathode interface modification layer contains a compound AxByCz, A is an element of Group IA or IIA, B is an element of Group IIIA or VA, C is a hydrogen element, and 1≦x≦2, yε[0,1], 1≦z≦4. In the present invention, the cathode interface modification layer is formed after forming a light emitting layer, the cathode interface modification layer contains a compound AxByCz, the electron injection ability at the cathode interface can be improved by adding the cathode interface modification layer, and hence the device performance can be significantly improved. At the same time, the process feasibility of the material is good during the fabrication, and thus the yield of the device can be further improved.
US08367217B2 Electrodeposited metallic-materials comprising cobalt on iron-alloy substrates with enhanced fatigue performance
Free standing articles or articles at least partially coated with substantially porosity free, fine-grained and/or amorphous Co-bearing metallic materials optionally containing solid particulates dispersed therein, are disclosed. The electrodeposited metallic layers and/or patches comprising Co provide, enhance or restore strength, wear and/or lubricity of substrates without reducing the fatigue performance compared to either uncoated or equivalent thickness chromium coated substrate. The fine-grained and/or amorphous metallic coatings comprising Co are particularly suited for articles exposed to thermal cycling, fatigue and other stresses and/or in applications requiring anti-microbial properties.
US08367216B2 Laminate for laminated glass and interlayer film for laminated glass
A laminate for a laminated glass which is used as a head-up displays (HUD) and is not deteriorated even if exposed to light, and with which a laminated glass having excellent impact resistance can be prepared, wherein an interlayer film for a laminated glass and a retardation element sandwiched between adhesive layers are laminated, the interlayer film for a laminated glass contains a thermoplastic resin and an ultraviolet absorber, the interlayer film for a laminated glass contains, as the ultraviolet absorber, a benzotriazole compound or a benzophenone compound, and at least one compound selected from the group consisting of a malonic ester compound, an oxanilide compound and a triazine compound.
US08367213B2 Biochemical instrument having surface that inhibits nonspecific adsorption
An object of the present invention is to provide a biochemical instrument having a surface that can simultaneously inhibit adsorption of a biopolymer and that of a hydrophobic low-molecular-weight compound. The present invention provides a biochemical instrument comprising a region that inhibits adsorption of a hydrophobic low-molecular-weight compound and a region that inhibits adsorption of a biopolymer on the surface of a water-insoluble material.
US08367209B2 Nanoengineered composite defog coating
An engineered nano-composite coating may include hydrophobic an hydrophilic domains, may be applied to transparent and non-transparent substrates using a continuous process, may be UV curable and may impart antifogging characteristics to the substrate.
US08367207B2 Method of producing a hydrogenated amorphous carbon coating
The invention relates to a hydrogenated amorphous carbon coating and to a method for the production thereof. It also relates to devices having such a coating. The method of the invention consists in producing a hydrogenated amorphous carbon coating comprising at least two layers of hydrogenated amorphous carbon, each of said layers having chemical compositions and physical and mechanical properties that are identical, and with thicknesses that are identical or different. The coating of the invention finds many applications, in particular in the mechanical field for parts subject to considerable wear and rubbing problems. It may also be applicable, in particular, in the field of surgical implants and in the MEMS (microelectromechanical systems) field.
US08367206B2 Fine barium titanate powder
Provided is barium titanate based powder represented by Chemical Formula 1: (BaxR1r1R2r2)(TiyR3r3R4r4)O3  [Chemical Formula 1] wherein R1 is at least one element selected from the group consisting of yttrium (Y) and lanthanoids; R2 is at least one element selected from the group consisting of magnesium (Mg), calcium (Ca) and strontium (Sr); R3 includes phosphorus (P) and niobium (Nb); R4 is at least one element selected from the group consisting of aluminum (Al), vanadium (V), chrome (Cr), manganese (Mn), cobalt (Co), zirconium (Zr) and tantalum (Ta); r1 and r3 independently represent a real number greater than 0 and equal to or less than 0.05; r2 and r4 independently represent a real number greater than 0 and equal to or less than 0.1; and (x+r1+r2)/(y+r3+r4) is a real number ranging from 0.85 to 1.15.
US08367205B2 Plate-like polycrystalline particle
A plate-like polycrystalline particle is produced by forming inorganic particles into a freestanding shaped body, firing the shaped body, and crushing and classifying the fired shaped body. The inorganic particles contain as the main component an oxide that has a general formula of ABO3 and that satisfies a×Pb(M′1/3,Nb2/3)O3+b×PbTiO3+c×PbZrO3+z×M″O (wherein a+b+c=1, and M′ denotes at least one element selected from Mg, Ni and Zn, and M″ denotes at least one element selected from Mg, Ni and Zn), wherein z is in the range of 0.002≦z≦0.42. The oxide contains a predetermined excessive amount of M″O such that the plate-like polycrystalline particle contains an excessive amount of M″O. The plate-like polycrystalline particle contains a plurality of crystal grains that have a wavy structure composed of wavy grain boundaries. The plate-like polycrystalline particle is easily crushed at the grain boundaries and has a high degree of orientation.
US08367200B2 Reflecting film excellent in cohesion resistance and sulfur resistance
A reflecting film including: an Ag or Ag-base alloy thin film of an Ag-base alloy containing at least one element among Au, Pt, Pd, Bi, and rare-earth elements as a first layer; a film of an oxide or oxynitride of at least one element among Si, Al and Ti having a thickness between 5 and 50 nm as a second layer deposited on the first layer; and a film having a thickness between 10 and 100 nm formed by a plasma polymerization process as a third layer deposited on the second layer.
US08367199B2 Biaxially oriented film
An object of the present invention is to provide a thin biaxially oriented film excellent in dimensional stability against humidity change, as well as a magnetic recording medium and a film capacitor using the same. The present invention provides a single layered or laminated biaxially oriented film comprising an aromatic polyester (a) and a polyolefin (b) having a melting point of from 230 to 280° C., wherein the ratio of the polyolefin (b) is from 5 to 30% based on the entire weight of the film, and the film thickness is from 1 to 10 μm.
US08367197B2 Composition for rigid polyurethane foam and rigid polyurethane foam produced using the same
A composition for a rigid polyurethane foam with reduced cell sizes contains a polyol, water, a catalyst, a blowing agent; and an ionic liquid. The rigid polyurethane foam is produced by adding an ionic liquid as an eco-friendly additive to a polyol composition so as to improve insulation efficiency thereof.
US08367196B2 Graphite material
A graphite material includes a plurality of graphite particles and a plurality of pores. The plurality of graphite particles and the plurality of pores form a microstructure. A ratio of an elastic modulus to a compression strength of the graphite material ranges from 109 to 138. Preferably, a ratio of a total area of the pores to a whole area of the graphite material in a cross-section of the graphite material ranges from 17.94% to 19.97%.
US08367195B2 Products made from recycled cardboard
A method of making a structural component (and such a structural component) comprising mixing together wood pulp, water, bentonite clay, and calcium chloride and forming the mixture into the structural component.
US08367193B1 Aqueous nanocomposite dispersions containing invisible marker dye for transparent barrier coatings and preparations and use thereof
The invention relates in one aspect to a post-formulation concentrated nanocomposite dispersion containing an invisible marker dye. The dispersion typically includes a silicate filler and a matrix polymer dispersed in an aqueous medium as well. The dispersions form optically transparent barrier films wherein the dye is effective to indicate film thickness on a substrate. Specific embodiments of this invention include a nanocomposite coating formulation designed to provide transparent high barrier coatings at thicknesses from 1 to 10 microns that include a near infrared (NIR) or infrared (IR) dye that enables rapid measurement of coating thickness and uniformity. The preferred dye imparts no observable color or appearance change, and thus can also function as an identifier for the coating.
US08367191B2 Optical thin-films and optical elements comprising same
Optical thin-films are disclosed that are formed from optical thin films formed on a base plate arranged in a vacuum chamber. The base plates are held on a plurality of retaining frames of a base-plate retainer. The thin films are formed by heating the base plate and emitting a deposition material from a deposition source. The retaining frames are configured to make the entire base plate uniformly heated.
US08367189B2 Pattern printed transparent sheet
A non-visible light reflective pattern-printed transparent sheet having a broad read angle is provided. The above transparent sheet is a pattern-printed transparent sheet in which a transparent substrate comprises a base material and a primer layer, and a non-visible light reflective transparent pattern is printed on the surface of the primer layer; an ink constituting the transparent pattern described above contains a material having a wavelength selective reflectivity to a wavelength in an infrared or ultraviolet region; the primer layer described above comprises a primer composition repelling the ink described above; when a cross section obtained by cutting the transparent pattern described above in a face orthogonal to the above transparent substrate is observed under a scanning electron microscope, the transparent pattern described above comprises a multilayer structure comprising a fixed repeating cycle and having a curved part and reflect selectively one of a left circularly polarized light component and a right circularly polarized light component in an incident light.
US08367188B2 Authenticity mark in the form of luminescent substances
A printed document of value has an authenticity feature in the form of at least two luminescent substances on the basis of host lattices which are doped with one or a plurality of ions. By systematically changing the host lattices and/or ions of the (nd)3 electron configuration a specific setting of the luminescence properties of luminescent substances is possible, the combination of which permits a multiplicity of complex new authenticity features.
US08367184B2 Structured films having acoustical absorbance properties
Structured films having acoustical absorbance properties are disclosed. Methods of making and using the structured films are also disclosed.
US08367183B2 Sandwich panel including honeycomb structure body and method of producing the sandwich panel
The breadth and width of a sheet-like filler material before it is placed in a cell of a honeycomb material is set greater than those of the honeycomb material, and after the placement, peripheral edges of the honeycomb material are fringed with filler materials to prevent a filler material from falling out of an end section cell. A liquid adhesive agent is applied to the top of cell walls facing one surface of the honeycomb material, and a surface material is pressed to that surface of the honeycomb material to which the adhesive agent is applied. Then, before the adhesive agent hardens, water-absorbing foam materials are placed in cell spaces by pressing them into the cell spaces from the other surface of the honeycomb material until they are in contact with the adhesive agent. The foam material is quickly adhered to the honeycomb material.
US08367182B2 Wrappable textile sleeve with integral attachment and closure device
A wrappable textile tubular sleeve for routing and protecting elongate members is provided. The sleeve includes an elongate wall constructed from interlaced yarns. The wall has opposite inner and outer edges extending between opposite ends of the sleeve parallel to a central longitudinal axis of the sleeve. The wall also has oppositely facing inner and outer faces extending between the inner and outer edges. The inner face bounds an inner cavity of the tubular sleeve upon wrapping the outer edge in outwardly overlapping relation with the inner edge about the central longitudinal axis. Further, an elongate fastener extends parallel to the central longitudinal axis adjacent the outer edge. The fastener faces outwardly from the outer face and is configured for attachment to an external support member.
US08367181B2 Apparatus and methods for making pile articles and improved pile articles made therewith
Filamentary materials, such as yarn (18), is wound a frame (28), provided by pairs of movable filaments or wires (35, 38), about which the end of the spindle (22) rotates provides the turns (26) of the winding as the article having the winding is moved along a process path. Mechanically or hydraulically actuated pins (34) support the winding frame in a fixed position. The filaments of the frame may be provided by laterally spaced pairs (44, 46) of filaments of weldable material.
US08367180B2 Cold chain packaging
A cold chain package including a plurality of panels surrounded by an overwrap, each of the panels including a plurality of layers of dissimilar materials, and a hinge formed between adjacent panels of the plurality of panels for facilitating folding of the panels to fit in a shipping container.
US08367174B2 Propylene-hexene random copolymer produced in the presence of a metallocene catalyst
Propylene copolymer a. comprising at least 1-hexene as a comonomer, b. having a comonomer content in the range of 1.0 to 3.0 wt.-%, c. having a xylene soluble fraction equal or below 2.5 wt.-%, d. having a polydispersity index (PI) of equal or below 4.0 Pa−1, and e. being partially crystallized in the β-modification.
US08367172B2 Blow-molded composite compositions and methods
A blow-molded composite and method of making the same is provided. The composite includes first and second fibrous layers and first and second film layers. The first fibrous layer includes randomly oriented fibers dispersed throughout the thickness of the layer and has first and second surfaces. The first film layer has first and second surfaces such that the second surface of this layer is bonded to the second surface of the first fibrous layer. The second film layer has first and second surfaces as well, but only a portion of the first surface is bonded to the first surface of the first film layer. At least one cavity exists between the first and second film layers. The second fibrous layer also comprises randomly oriented fibers dispersed throughout the thickness of the layer and has first and second surfaces. The first surface of the second fibrous layer is bonded to the second surface of the second film layer.
US08367171B2 Polymer having polycyclic groups and coating compositions thereof
A polymer and coating composition containing the polymer are provided that are useful in coating applications such as, for example, food or beverage packaging containers. The polymer preferably includes a backbone having one or more polycyclic groups. In one embodiment, the polymer is a polyester and, more preferably, a polyester-urethane polymer. In one embodiment, the one or more polycyclic groups is a tricyclic or higher group.
US08367166B2 Synthesis of higher diamondoids
In some embodiments, the present invention is directed to methods for synthesizing higher diamondoids, wherein said methods involve augmenting existing diamondoid molecules through the bonding of carbon atoms to such existing diamondoid species with intramolecular cross-linking so as to form larger diamondoids containing face-fused diamond-crystal (adamantane) cages with carbon frameworks superimposable on the cubic-diamond crystal lattice.
US08367165B2 Method of applying a water-base adhesive mix for producing tyres
A method of applying a water-base adhesive mix for producing tires, the method including a step of applying a layer of adhesive mix to a work surface; and a step of drying the layer, and which includes microwave heating.
US08367164B2 Method of manufacturing nano-template for a high-density patterned medium and high-density magnetic storage medium using the same
Disclosed is a method for manufacturing a template for a high-density patterned medium and a high-density magnetic storage medium using the same. In the method, magnetic particles are used as a mask and no lithographic process is required.
US08367163B2 Enamel flow coating process and apparatus
An enamel flow coating process and apparatus is arranged as a four arm Ferris wheel like apparatus which is mounted over a bathtub like tank which holds enamel slip. Coils of steel tubing formed into heat exchangers are mounted to the arms of the wheel to rotate and to pivot. The wheel is rotated between four stations. In the first station, a coil is loaded onto the wheel. In a second station the coil is pivoted into the tank of enamel slip, where it is coated, and withdrawn by operation of a pivoting bracket. The coated coils are rotated through third and fourth stations where the coating solidifies, and the coated heat exchanger is removed, and replaced with an uncoated one in the first station. After leaving the wheel, the heat exchanger is fired and installed in a water storage tank.
US08367162B2 Pretreatment method for improving antioxidation of steel T91/P91 in high temperature water vapor
Disclosed is a pretreatment method for improving antioxidation of steel T91/P91 in high temperature water vapor, which includes applying a slurry, containing rare earth oxide, on a surface of a substrate; holding the temperature in a gas mixture environment of inert gas and water vapor after drying; and cleaning away the solid powder left by the slurry on the surface, thereby obtaining the substrate with a surface rich in chromium and having a small amount of rare earth oxide. As a result of the method, the antioxidation capability of steel T91/P91 in the 500-750° C. water vapor environment can be improved, and films rich in chromium oxide can be formed on the surface of steel T91/P91.
US08367160B2 Coating method for reactive metal
A coating method includes depositing a reactive material onto a turbine engine component using an ionic liquid that is a melt of a salt, and heat treating the turbine engine component to react the reactive material with at least one other element to form a protective coating on the turbine engine component.
US08367159B2 Methods for producing ZMWs with islands of functionality
The application relates to methods for producing islands of functionality within nanoscale apertures. Islands of functionality can be produced by growing an aperture constriction layer from the walls, functionalizing the exposed base of the aperture, then removing the aperture constriction layer. The aperture constriction layer can be produced, for example, by anodically growing an oxide layer onto a cladding through which the aperture extends. The islands of functionality can be used to bind a single molecule of interest, such as an enzyme within the nanoscale aperture.
US08367156B2 Method of manufacturing magnetoresistive device and apparatus for manufacturing the same
A magnetoresistive device has an MgO (magnesium oxide) layer provided between a first ferromagnetic layer and a second ferromagnetic layer. The device is manufactured by forming a film of the MgO layer in a film forming chamber. A substance whose getter effect with respect to an oxidizing gas is large is adhered to surfaces of components provided in the chamber for forming the MgO layer. The substance having a large getter effect is a substance whose value of oxygen gas adsorption energy is 145 kcal/mol or higher. Ta (tantalum), in particular, is preferable as a substance which constitutes the magnetoresistive device.
US08367152B2 Manufacturing method of light-emitting device
For a full-color flat panel display, demands for high definition, high aperture ratio and high reliability have been increasing. Therefore, increasing in the number of pixels and narrowing a pixel pitch have been major issues. According to the present invention, a layer including an organic compound is selectively formed with a light-exposure apparatus used in a photolithography technique without a resist mask. A material layer including a photopolymerization initiator, a material polymerized with the photopolymerization initiator, and an organic compound are formed on a plate, and then are exposed to light and selectively cured. A film-formation substrate is disposed so as to face the plate. The film-formation substrate or the material layer is heated so that the organic compound included in a region exposed to light or a region not exposed to light is evaporated to be selectively deposited on the surface of the film-formation substrate.
US08367146B2 Confectionery made from herbal mixtures
Confectionery made from herbal mixtures, comprising an extract from a mixture of several herbs, or a mixture of a corresponding number of extracts of at least one herb, with additionally an extract of Stevia rebaudiana. The above presents considerable advantages, in particular: a desired flavor change, sweetening with a high sweetening capacity, natural sweetening without additional calories, natural sweetening without causing caries and with a prophylactic effect on caries. The confectionery can be produced, whereby either the dry herbs are mixed, said mixture extracted and the extract optionally thickened, or a corresponding number of optionally thickened extracts of at least one of the dried herbs are combined with each other and the mixture thickened, whereupon the mixture obtained is mixed with optionally thickened extract of the dried herb Stevia rebaudiana, or the dried herbs and the dried herb from Stevia rebaudiana are mixed together, said mixture is extracted and the extract obtained is optionally thickened. The obtained mixture or the obtained optionally thickened extract is processed to give confectionery of the desired form. The confectionery can be in many forms, such as a conventional form and produced by conventional means.
US08367145B2 Acidic protein food or drink and material thereof
The problem to be solved by the invention is to provide a food or a drink containing an acidic protein which has a favorable flavor with relieved astringency characteristic to a protein dissolved under acidic conditions to thereby broaden the flavor variety of protein-containing foods or drinks. The above problem can be solved by adding a water soluble polysaccharide, a water soluble basic salt, an alkali metal salt of an organic acid, a basic monosaccharide, a basic oligosaccharide or the like to a food or a drink containing a protein dissolved under acidic conditions to thereby relieve the astringency originating in the protein dissolved under acidic conditions.
US08367141B2 Instant black tea containing green tea extract
Provided is an instant black tea, which includes the non-polymer catechins at high concentration, is further reduced in bitterness and astringency, and is excellent in the appearance of its infusion. The instant black tea includes a beverage material containing black tea leaves and a dried green tea extract and sealed in a tea bag. A mass ratio of the non-polymer catechins/tannin in the beverage material is from 0.65 to 0.95.
US08367140B2 Concentrate composition for drink from concentrate
A concentrated beverage composition for reconstitution is reduced in bitterness and astringency, adequate in both sweetness and sourness and improved in storage stability despite the inclusion of a high concentration of non-polymer catechins. The concentrated beverage composition for reconstitution contains (A) from 0.5 to 25.0 wt % of non-polymer catechins, (B) a carbohydrate, and (C) a hydroxycarboxylic acid, and meets the following conditions (D) and (E) as well as at least one condition selected from the following conditions (F1), (F2) and (F3): (D) a content of gallic acid is lower than 0.6 wt %, (E) a percentage of non-epi-forms in the non-polymer catechins is from 5 to 25 wt %, (F1) a Brix degree is from 20 to 70, and when diluted with deionized water to give a non-polymer catechin concentration of 0.13 wt %, a pH is from 2.5 to 6.0, (F2) a solid content is not lower than 70.0 wt %, and when diluted with deionized water to give a non-polymer catechin concentration of 0.13 wt %, a pH is from 2.5 to 6.0, and (F3) an absorbance at 400 nm is smaller than 0.5 and a pH is from 2.5 to 6.0, when diluted with deionized water to give a non-polymer catechin concentration of 0.13 wt %.
US08367137B2 High-potency sweetener composition with fatty acid and compositions sweetened therewith
The present invention relates generally to functional sweetener compositions comprising non-caloric or low-caloric natural and/or synthetic, high-potency sweeteners and methods for making and using them. In particular, the present invention relates to different functional sweetener compositions comprising at least one non-caloric or low-caloric natural and/or synthetic, high-potency sweetener, at least one sweet taste improving composition, and at least one functional ingredient, such as fatty acids. The present invention also relates to functional sweetener compositions and methods that can improve the tastes of non-caloric or low-caloric high-potency sweeteners by imparting a more sugar-like taste or characteristic. In particular, the functional sweetener compositions and methods provide a more sugar-like temporal profile, including sweetness onset and sweetness linger, and/or a more sugar-like flavor profile.
US08367133B2 Capsule and configuration for foaming a liquid food
For the production from a liquid food of an at least partially foamed food, in particular at least partially foamed milk or a milk product, the liquid food, which is contained in a container (1) or a capsule-type formation, is expelled from the container or the capsule, and at least partially foamed and subsequently expelled by generating an at least partially turbulent flow.
US08367127B2 Tea beverages containing proanthocyanidins
The object is to provide beverages that allow for sustained intake and which have an effect of improving the vascular endothelial function as by promoting the secretion of NO from vascular endothelial cells so as to potentiate the NO action.The object is attained by providing proanthocyanidins containing tea beverages that contain procyanidin B1 (PB1) and procyanidin B3 (PB3) in a total amount not smaller than a certain concentration and which are free from any peculiar flavor to become easier to drink; they allow for sustained intake and have an effect of improving the vascular endothelial function.
US08367126B2 Berry preparations and extracts
Compositions having antioxidant and anti-inflammatory activity, and methods for providing such compositions, are disclosed. In one aspect, the compositions are derived by exposing a berry to an acidic solvent composition, adding a cryoprotectant, and recovering a berry extract having a stabilized anthocyanin content. Compositions comprising the stabilized anthocyanin-containing berry extract, formulated for oral and/or topical administration, are provided also.
US08367125B2 Method of improving the water quality in aquatic ecosystems
A method for improving water quality in aquatic ecosystems is described. An effective amount of Quercus infectoria nut gall powder is added to the ecosystem to prevent excessive proliferation of pathogenic bacterial species thereby improving the health of aquaculture species in the ecosystem.
US08367121B2 Nutraceutical agent for attenuating the neurodegenerative process associated with Parkinson's disease
This invention describes a comprehensive nutraceutical designed to antagonize major mitigating factors to the degenerative process associated with Parkinson's disease. The formulation is comprised of a primary base of pyruvate, succinate, α-Ketoglutarate and/or oxaloacetate, niacin/NADH, fruit extracts, anthocyanins, further combined with specific macro/micronutrients, trace elements, amino acids, flavonoids and concentrated plant sources. The nutraceutical contains all natural substances that should mitigate many of the neurodegenerative processes known to be associated with PD. Mechanisms addressed are to prevent the loss of ATP/by 1-methyl-4-phenylpyridinium rotenone, scavenge hydrogen peroxide/O2.−, augment antioxidant enzymes, prevent dopamine (DA) oxidation to DA-quinone via inhibition of COX, PLA2, LOX, xanthine oxidase, tyrosinase, prevent hyperhomocysteinemia, antagonize PARP-1 apoptosis, increase blood flow, glucose and oxygen delivery to the brain, potentiate mitochondrial function, antagonize glia iNOS and MAO or its products, chelate redox-active iron, inhibit heme oxygenase-1, inhibit alpha-synuclein aggregation, augment ATP storage, mediate anti-inflammatory effects via inhibition of PDE, MAPK p38/c-Jun NH2-terminal kinase/PGE2, antagonize excitotoxicity and downregulate N-methyltransferase, all of which contribute toward PD pathology.
US08367113B2 Polymers for functional particles
The present invention generally relates to polymers and macromolecules, in particular, to block polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of developing nanoparticles with desired properties. In one set of embodiments, the method includes producing libraries of nanoparticles having highly controlled properties, which can be formed by mixing together two or more macromolecules in different ratios. One or more of the macromolecules may be a polymeric conjugate of a moiety to a biocompatible polymer. In some cases, the nanoparticle may contain a drug. The moiety, in some embodiments, may have a molecular weight greater than about 1000 Da; for example, the moiety may include a polypeptide or a polynucleotide, such as an aptamer. The moiety may also be a targeting moiety, an imaging moiety, a chelating moiety, a charged moiety, or a therapeutic moiety. Another aspect of the invention is directed to systems and methods of producing such polymeric conjugates. In some embodiments, a solution containing a polymer is contacted with a liquid, such as an immiscible liquid, to form nanoparticles containing the polymeric conjugate. Other aspects of the invention are directed to methods using such libraries, methods of using or administering such polymeric conjugates, methods of promoting the use of such polymeric conjugates, kits involving such polymeric conjugates, or the like.
US08367112B2 Nanoparticulate carverdilol formulations
The present invention is directed to nanoparticulate carvedilol compositions having improved pharmacokinetic profiles, improved bioavailability, dissolution rates and efficacy. In one embodiment, the nanoparticulate carvedilol composition has an effective average particle size of less than about 2000 nm.
US08367111B2 Extended release dosage forms of propranolol hydrochloride
A unit dosage form, such as a capsule or the like for delivering drugs into the body in a sustained release fashion similar to that produced by INDERAL® LA indicated for the treatment of cardiovascular diseases, comprises two populations of propranolol-containing particles (beads, pellets, granules, etc.). Each bead population exhibits a pre-designed rapid release profile (i.e., substantially complete release within 60 minutes) or sustained release profile over a period of 24 hours. Such a cardiovascular drug delivery system is designed by combining immediate release (IR) beads and sustained release (SR) beads. SR beads may be obtained by membrane coating IR beads with a water-insoluble polymer such as ethylcellulose or a mixture of a water insoluble polymer and a water-soluble polymer such as hydroxypropylcellulose at a ratio of from about 65/35 to 95/5.
US08367108B2 Functionalized non-phenolic amino acids and absorbable polymers therefrom
The present invention relates to compound of formula I, which are functionalized, non-phenolic amino acids, and polymers formed from the same. Polymers formed from the functionalized amino acids are expected to have controllable degradation profiles, enabling them to release an active component over a desired time range. The polymers are also expected to be useful in a variety of medical applications.
US08367106B2 Compressed solid dosage form manufacturing process well-suited for use with drugs of low aqueous solubility and compressed solid dosage forms made thereby
A pharmaceutical formulation of compounds with low aqueous solubility and method of manufacture thereof. The formulation may include a pharmacologically active compound having low aqueous solubility and starch in the amount of greater than about 25 weight percent. A manufacturing method may include blending the active compound and starch, compressing the blend into a solid, comminuting the solid into granules, wetting the granules, drying the granules, and tabletting the dried granules to make a solid pharmaceutical formulation.
US08367103B2 Oral testosterone composition
The composition for oral administration of testosterone to a man who has androgen deficiency and exhibits one or more symptoms of androgen deficiency, comprises testosterone and a mixture of soybean oil and ethanol. Preferably, a pharmaceutically acceptable preservative, such as benzyl alcohol, is included in the composition. The mixture of soybean oil and ethanol is present in the composition in an amount such that when the composition is orally ingested by the testosterone is absorbed and one or more of the symptoms of androgen deficiency is ameliorated. The composition is charged into hard or soft gelatin capsules to produce orally administrable unit dosage forms.
US08367100B2 Preparation and use of sleeve and micro-encapsulated topical analgesic patch for treating pain
Novel micro-encapsulated topical analgesics are provided to treat pain and may be applied via sleeves having dosed therapeutic sections, especially to joints and extremities. Sleeves may be prepared and packaged inside-out and inverted when positioned by the wearer.
US08367097B2 Liquid formulations for treatment of diseases or conditions
Diseases and conditions associated with tissues of the body, including but not limited to tissues in the eye, can be effectively treated, prevented, inhibited, onset delayed, or regression caused by administering therapeutic agents to those tissues. Described herein are liquid formulations which deliver a variety of therapeutic agents, including but not limited to rapamycin, to a subject for an extended period of time; liquid formulations which form a non-dispersed mass when placed in an aqueous medium of a subject; non-dispersed mass-forming liquid formulations which form a gel or gel-like substance in an aqueous medium; liquid formulations, comprising a therapeutic agent and a plurality of polymers; and methods for delivering therapeutic agents to a subject for an extended period of time using the liquid formulations. The liquid formulation may be placed in an aqueous medium of a subject, including but not limited to via intraocular or periocular administration, or placement proximate to a site of a disease or condition to be treated in a subject. A method may be used to administer rapamycin to treat or prevent angiogenesis, choroidal neovascularization, or age-related macular degeneration, or wet age-related macular degeneration in a subject. The liquid formulations may comprise rapamycin or other therapeutic agents.
US08367094B2 Antimicrobial material and method for making the same
This invention provides a modified catheter/indwelling device biomaterial that provides both immediate, and long-term microbiocidal effects on otherwise antibiotic-resistant strains of microorganisms. The material, which exhibits good mechanical performance characteristics for medical devices, is composed of a hydrophobic polyurethane (PU), a hydrophilic polyethylene vinyl acetate (PEVA) as an option, a soluble silver salt and a sparsely-soluble silver salt. The hydrophobic polyurethane provides the good physical properties, the PEVA the hydrophilicity necessary to allow some water ingress into the catheter, the soluble silver salt for an immediate burst effect, and the sparsely-soluble silver salt for sustained-release over many months postimplantation. Alternatively, the sparsely soluble silver salt can be silver iodate and is combined with silver sulfadiazine. Chlorhexidine can also be included in the material.
US08367092B2 Method for modifying the wettability and/or other biocompatibility characteristics of a surface of a biological material by the application of gas cluster ion beam technology and biological materials made thereby
The invention provides methods for surgical grafting of a tissue. The method comprises the steps of explanting a graft tissue from a donor, irradiating at least a first portion of the graft tissue with an ion beam, and surgically grafting the graft tissue into a recipient.
US08367091B2 Coatings for implantable medical devices
Coatings for implantable medical devices comprising non-fouling moieties or polymers chemically bonded to the surface of the device via chelating structures, and methods of fabricating the coatings are disclosed.
US08367088B2 Liquid pest control formulation
The present invention relates to a liquid pest control system that includes a synthetic pyrethroid as a pest control active ingredient and an agent selected from the group consisting of purified diethylene glycol monoethyl ether, tocopherol nicotinate and tocopherol succinate, and combinations thereof, to reduce or eliminate paraesthesia of the synthetic pyrethroid. The system releases the synthetic pyrethroid efficiently and uniformly. The pest control system is less irritating to the animal's skin as compared to prior art systems, particularly to the small breeds of dogs. The system is useful for making liquid spot-on treatments, sprays and the like.
US08367087B2 Soil amendment compositions and methods for using the same
Soil amendment compositions and methods for using the same are provided. The subject compositions are aqueous compositions consisting essentially of a carbon-skeleton energy component, a predisposing agent and a vitamin-cofactor component. The subject compositions find use in a variety of soil amendment applications, including: the control of soil born pests and pathogens; the improvement in soil fertility and/or characteristics, e.g. mineral release, water filtration; the neutralization and/or degradation of toxins, etc.
US08367078B2 Kinase inhibitor compounds
The invention relates to kinase inhibitor compounds and methods of identifying and using them. The invention further relates to pharmaceutical compositions and methods for treating disorders, especially cancer.
US08367077B2 Virosomes comprising hemagglutinin derived from an influenza virus produced in a cell line, compositions, methods of manufacturing, use thereof
The present invention relates to virosomes comprising hemagglutinin (HA) with improved fusion activity. Preferably, the HA comprised in said virosomes was derived from influenza virus produced in a cell line. The present invention also relates to compositions and a kit comprising the virosomes according to the invention. Further, the present invention relates to uses and methods involving said virosomes, as well as to a method for preparing same.
US08367072B2 Composition for treating obesity and method of using the same
A composition for a medicinal or health effect of a treatment of liver fat and body fat, a reduction of blood pressure, an increase of the energy expenditure rate, a reduction of inflammatory C-reactive proteins and a reduction of plasma aminotransferase enzymes, comprising an effective amount of fucoxanthin alone or in combination with pomegranate seed oil, a pharmaceutically acceptable salt, a prodrug thereof, or a salt of the prodrug; and a method of using the same. The fucoxanthin may be used in pure form, or as a component of a brown marine vegetable extract.
US08367070B2 Modified surface antigen
Novel proteins that constitute modified forms of a Neisseria meningitidis surface antigen and encoding nucleic acids are provided. The modified surface proteins are characterized by having deletions of non-conserved amino acids, and thereby being capable of eliciting cross-protective immune responses against Neisseria meningitidis. The invention extends to the use of the modified surface antigens in diagnostics, in therapeutic and prophylactic vaccines and in the design and/or screening of medicaments. The modified surface antigens are particularly useful in vaccines which effectively immunize against a broader spectrum of N. meningitidis strains than would be expected from a corresponding wild-type surface antigen.
US08367063B2 Human anti-OPGL neutralizing antibodies as selective OPGL pathway inhibitors
Monoclonal antibodies and hybridomas producing them that interact with osteoprotegerin ligand (OPGL) are provided. Methods of treating osteopenic disorders by administering a pharmaceutically effective amount of antibodies to OPGL are also provided. Methods of detecting the amount of OPGL in a sample using antibodies to OPGL are further provided.
US08367062B2 Glycopeptides derived from pancreatic structures, antibodies and applications thereof in diagnostics and therapeutics
Glycopeptide comprising 1 to 40 repeated C-terminal polypeptides, with 11 amino acids, of BSDL or FAPP, whereby said polypeptides are glycosylated and bear glycosylated epitopes giving rise to a specific immunological reaction with induced antibodies in a patient suffering from type 1 diabetes and/or purified from biological fluids of human or animal origin or recombinant and produced by expression in a standard host cell comprising an enzymatic material necessary for priming a glycosylation, said host cell being genetically modified such as to comprise a gene coding for said polypeptides and a gene coding for one or more enzymes selected from among glycosyltransferases, anti-glycopeptide antibodies and the applications thereof in therapeutics and diagnostics.
US08367058B2 Method for bacteriophage delivery and amplification
Disclosed are methods of selecting wide host range bacteriophage capable of growing in a plurality of bacteria including pathogenic and non-pathogenic bacteria and bacteriophage selected by the methods. Also disclosed are methods of treating a subject infected with a pathogenic bacterium using bacteriophage and methods of decontaminating objects using bacteriophage. Also disclosed are methods of producing vaccines. In another aspect, methods of determining bacterial viability and methods of improving the sensitivity of a biosensor using wide host range bacteriophages are disclosed.