Document Document Title
US08350775B2 Antenna arrangement for a mobile radio base station
An improved antenna arrangement includes a reflector arrangement comprising a printed circuit board with an electrically conductive ground plane. The reflector arrangement also has a reflector frame with a coupling surface. The coupling surface is capacitively coupled to the ground plane. The coupling surface has a recess via which the ground plane, which is located underneath it, and/or the printed circuit board or an isolating intermediate layer which is provided above the ground plane or an isolating intermediate layer which is provided above the printed circuit board is exposed. The at least one antenna element arrangement is positioned and/or held on the printed circuit board in the area of the recess.
US08350774B2 Double balun dipole
A double balun dipole antenna element includes a dielectric substrate having a first surface and an opposing second surface, a pair of coplanar Marchand baluns positioned in a mutually antiphase configuration on the first and second surfaces, and at least one feed line connected to the pair of Marchand baluns. A doubly polarized antenna element includes a pair of orthogonally interleaved double balun dipole antenna elements, which can be further configured into an array of such antenna elements.
US08350771B1 Dual-band dual-orthogonal-polarization antenna element
A dual-band, dual-orthogonally-polarized antenna element includes a dielectric substrate having a conductor layer that includes a square ring slot and a shorted square ring, with each having a pair of orthogonal feed points. The shorted square ring is fed with coaxial probe feeds, while the square ring slot feeds striplines terminated in open-circuited stubs for coupling energy to each pair of orthogonal feed points. The first and second stripline feeds are not coplanar in order that each stub terminates past a center point of the element. The square ring slot operates as a high frequency band radiator and the shorted square ring operates as a low frequency band radiator, and both bands radiate substantially simultaneous dual-orthogonally-polarized modes. The modes can be any combination of dual-Circular Polarization (CP) and dual-Linear Polarization (LP), depending on the geometry of the radiators.
US08350766B2 Antenna-embedded laminated glass
The present invention provides an antenna-embedded laminated glass including glass sheets affixed together through an intermediate film to embed an antenna element between the glass sheets, the intermediate film containing a resin; and the antenna element being configured to have such a shape as to have an intersection where a plurality of antenna-forming strips intersect, and the antenna element comprising a conductor strip stamped in such a shape from a sheet-like conductor.
US08350765B2 Resonant cavity injection-based calibration of a radiant energy device
The present invention, as typically embodied, implements an energy source, a transmitting antenna, a receiving antenna, a resonant cavity, and an electricity meter (e.g., voltmeter, ammeter, or power meter) to calibrate an electronic device. Firstly, the receiving antenna is calibrated based on measurement of power that has been generated and transmitted in known quantity, propagated through air, and received by the receiving antenna. Secondly, the resonant cavity is connectively situated between the transmitting antenna and the receiving antenna; the resonant cavity is calibrated based on measurement of power that has been generated and transmitted in the same quantity, propagated through the resonant cavity, and received by the receiving antenna. Thirdly, an electronic device is substituted for the receiving antenna; the electronic device is calibrated based on measurement of power that has been generated and transmitted in the same quantity, propagated through the resonant cavity, and received by the electronic device.
US08350763B2 Active antennas for multiple bands in wireless portable devices
Wireless devices, and particularly mobile devices such as cellphones, PDAs, computers, navigation devices, etc., as well as other devices which transmit or receive data or other signals at multiple frequency bands utilize at least one antenna to transmit and receive and a plurality of different bands (e.g., GSM cellular communication band; Bluetooth short range communication band; ultrawideband (UWB) communications, etc.). These wireless devices can simultaneously transmit or receive at a plurality of different bands, or simultaneously transmit and receive at different bands. The wireless devices have the ability to use a single physical structure (e.g., an antenna) for transmission and reception of many different bands. The antenna can be either actively tuned or passively tuned using one or more elements.
US08350761B2 Antennas for handheld electronic devices
Handheld electronic devices are provided that contain wireless communications circuitry having at least one antenna. The antenna may have a planar ground element and a planar resonating element. The planar ground element may have a rectangular shape that matches a rectangular housing shape for a handheld electronic device. A dielectric-filled slot may be formed in one end of the planar ground element. The planar resonating element may be located above the slot. The antenna may be a hybrid antenna that contains both a slot antenna structure formed from the slot and a planar inverted-F structure formed from the planar resonating element and the planar ground element. The antenna may be fed using a single transmission line or two transmission lines. With two transmission lines, one transmission line may be associated with the slot antenna structure and one transmission line may be associated with the planar inverted-F antenna structure.
US08350760B2 Antenna using buildup structure and method of manufacturing the same
There are provided an antenna using a buildup structure and a method of manufacturing the same. In the antenna, a tag chip is positioned within a dielectric and is connected to a radiator through a connection line or a via-hole, thereby being strong against external environments, decreasing a defective rate and enabling to be used for the special purpose of being positioned within a metal or liquid.
US08350758B1 Systems and methods for indoor geolocation based on yield of RF signals
Systems and methods are disclosed herein for determining a user's location within an indoor environment. In particular, the system receives a location request including a set of radio frequency signal data collected by a mobile device inside of an indoor environment. Using this data set, the system first selects a map from a plurality of maps stored in a map database. The system then processes the data to identify the user's location on the selected map. The system uses yield information associated with the received signals in determining the map that the user is on, the user's location on the map, or both the map and the user's location to filter out transient signals and identify those signals that are reliably indicative of the user's location.
US08350757B2 Method of processing a digital signal derived from an analog input signal of a GNSS receiver, a GNSS receiver base band circuit for carrying out the method and a GNSS receiver
An acquisition unit of a GNSS receiver base band circuit includes an integrator with a number of preprocessors where an incoming digital signal is mixed with different frequency signals to compensate at least in part for clock drift and Doppler shifts. The resulting digital signals are, after an accumulation step reducing sample frequency, integrated over an integration period extending over several basic intervals of the length of a basic sequence characteristic for a GNSS satellite, so that samples separated by a multiple of the basic interval are superposed. The resulting data sequence of 1,023 digital values is stored in one of two memories and then, in mixers, sequentially shifted by post-integration frequencies which are multiples of the inverse of the length of the basic interval. The pre-integration frequencies employed in the preprocessors deviate, with one possible exception, from the post-integration frequencies and are usually smaller.
US08350753B2 Methods and systems for displaying an object having an associated beacon signal
Systems and methods are provided for displaying information on a display device associated with an aircraft. A method comprises rendering a synthetic perspective view of terrain on the display device, wherein the synthetic perspective view of terrain is based on a set of terrain data corresponding to a region proximate the aircraft. The method further comprises obtaining location data for a first object, wherein the location data is based at least in part on a beacon signal associated with the first object, and rendering a graphical representation of the first object on the display device. The graphical representation of the first object overlies the synthetic perspective view of terrain and is positioned in accordance with the location data.
US08350751B2 Radar level gauge with improved radar window
A radar level gauge for determining the filling level of a product in a tank, comprising a transceiver for transmitting and receiving microwaves, processing circuitry connected to the transceiver and adapted to determine the filling level, an antenna connected to said transceiver and arranged to emit and receive microwaves through an opening of the tank, and a microwave transmissive sealing member adapted to cover said opening and to provide pressure sealing of the tank. The sealing member comprises a metal grid layer providing structural strength, which metal grid layer has sealed openings formed to allow transmission of microwaves.The tank opening is thus divided into a number of smaller openings by the metal grid, thereby improving the mechanical strength of the sealing member. At the same time, the sealing member is designed to maintain its pressure sealing properties, e.g. by suitable dielectric filling of the openings.
US08350748B2 Process and a device for automatically determining meteorological conditions in the vicinity of an aircraft
A process and a device for automatically determining meteorological conditions in the vicinity of an aircraft is disclosed. The device (1) comprises a meteorological radar (2), able to determine the meteorological information associated with a primary geographical area ahead of an aircraft, and means (3, 4A, 4B) for automatically determining the meteorological conditions associated with a geographical area being extended with respect to the primary geographical area.
US08350744B2 Virtual universal remote control
A method for providing a virtual, universal remote control feature includes displaying a virtual remote interface for an electronic device. A user interaction with an element of the virtual remote interface is detected. The virtual remote interface element is mapped to a device-function code. The device-function code is provided to a code transmitter. The device-function code corresponds to a control command associated with the electronic device.
US08350742B2 Method for digitizing an analogue signal with an analogue-digital converter of determined Shannon frequency
A method for forming a global spectrum (Sg) of an analogue signal (A) to be digitized, in which: the analogue signal (A) is sampled with a first analogue-digital converter (21, 22) of determined Shannon frequency (Fs) so as to obtain an aliasing spectrum (Sr), the analogue signal (A) not having been previously filtered by an anti-aliasing filter; a base spectrum (Sb) is subtracted from the aliasing spectrum (Sr) so as to obtain an aliased spectrum (Sre), the base spectrum (Sb) corresponding to an aliasing-free spectrum of the said analogue signal; a dealiased spectrum (Sd) is computed on the basis of the aliased spectrum (Sre) as a function of the Shannon frequency (Fs) of the converter (21, 22); the base spectrum (Sb) is concatenated with the dealiased spectrum (Sde) so as to form the global spectrum (Sg) of the analogue signal (A).
US08350736B2 Offset compensation scheme using a DAC
An offset compensation scheme using a digital-to-analog converter (DAC) is disclosed. In some embodiments, a DAC is coupled to a circuit having an undesired current or voltage offset and is configured to at least in part compensate for the undesired current or voltage offset. For example, in some embodiments, the DAC injects current or voltage into the circuit that shifts a current or voltage of the circuit by an amount equal or similar in magnitude but opposite in polarity to a shift in the current or voltage of the circuit caused by the undesired current or voltage offset.
US08350735B2 Method for coding and an apparatus
The disclosure relates to variable length encoding and decoding. A symbol is variable length encoded by selecting a variable length code word table from a set of variable length code word tables based on a value of a variable; selecting a code word from the selected variable length code word table on the basis of said symbol; and updating the value of said variable by comparing the correspondence between said symbol and said variable. If the comparison indicates that the value of the variable is smaller than the symbol, the value of said variable is incremented; else if the comparison indicates that the value of the variable is greater than the symbol, the value of said variable is decremented; else the value of the variable is not amended.
US08350733B2 Keyboard scan for human interface devices
Methods, apparatuses, and computer-readable media for scanning a keyboard are disclosed. Actuation of each of the keys electrically couples one of a plurality of first lines and one of a plurality of second lines. A first signal is applied to a plurality of first lines. A second signal is applied to a plurality of second lines. Upon identifying at least one of the second lines as presenting a signal different from the second signal, a scan signal is applied to the identified second line. At least one first line is identified as presenting a signal indicating the at least one first line is contact with the identified second line applying the scan signal. At least one of the keys is identified as causing the identified second line and the least one identified first line to be coupled.
US08350732B2 Compression with adjustable quality/bandwidth capability
The disclosure provides a system and method to vary bandwidth/speed of a compression engine to tradeoff with compression quality. The system comprises an input port receiving a data stream having a current byte and a stream of preceding and subsequent bytes thereof; a history memory storing the stream of preceding bytes in blocks of history data an index engine having a table of keys associated to memory addresses of the blocks, the index engine accessing the table to output a plurality of potential string matches upon entry of the current byte; a search engine processing the potential string matches by fetching the blocks of history data associated with each of the plurality of potential string matches and comparing a portion of each of the blocks to the current byte to output a string upon matching consecutive bytes in the block to the current byte and subsequent bytes thereof; and a control input limiting the number of potential string matches processed by the search engine.
US08350731B2 Complex-operation input device
A complex-operation input device having an operable knob held in a rotatable and slidable manner includes a rotation sensor that detects rotation of the operable knob on the basis of displacement of a second detected portion, and a slide sensor that detects sliding of the operable knob on the basis of displacement of a first detected portion. The direction in which the second detected portion moves with the sliding of the operable knob is substantially orthogonal to a rotation axis about which the operable knob rotates. The slide sensor is disposed such that, when the operable knob is slid, the slide sensor detects the sliding before the rotation sensor detects the displacement of the second detected portion.
US08350730B2 Keyboard scan
Methods, apparatuses, and computer-readable media for scanning a keyboard are disclosed. Actuation of each of the keys electrically couples one of a plurality of first lines and one of a plurality of second lines. A first signal is applied to a plurality of first lines. A second signal is applied to a plurality of second lines. Upon identifying at least one of the second lines as presenting a signal different from the second signal, a scan signal is applied to the identified second line. At least one first line is identified as presenting a signal indicating the at least one first line is contact with the identified second line applying the scan signal. At least one of the keys is identified as causing the identified second line and the least one identified first line to be coupled.
US08350729B2 Reduced QWERTY keyboard system that provides better accuracy and associated method
A handheld electronic device and an associated method are provided. The handheld electronic device includes a keyboard assembly, a display positioned adjacent the keyboard assembly, a processor structured to receive inputs from the keyboard assembly and to output to the display as a function of the inputs, the processor further structured to run a disambiguation routine. The keyboard assembly includes a printed circuit board, a primary conductor portion, a secondary conductor portion, and a keyboard assembly. The printed circuit board has a plurality of electrical contacts. The conductor assembly has a plurality of primary conductors and a plurality of secondary conductors, each the primary conductor and secondary conductor structured to correspond to, and engage and close, at least one of the plurality of electrical contacts. The keyboard assembly has a plurality of keys each having one or more indicia thereon.
US08350728B2 Keyboard with integrated and numeric keypad
A keypad includes a plurality of keys, and a processor that is coupled to control use of the keypad, including to enable use of the keypad in each of a letter entry mode or an alternative entry mode. The plurality of keys include a subset of keys, each key in the subset being (i) enlarged as compared to other keys of the keypad that are not part of the subset, (ii) assigned m letter values for when the keypad is operated in the letter entry mode, and (iii) assigned n numeric values, where 1≦n
US08350724B2 Rear parking assist on full rear-window head-up display
A substantially transparent head up display includes one of light emitting particles or microstructures over a predefined region of the substantially transparent head up display permitting luminescent display while permitting vision through the substantially transparent head up display. A method to display a graphic upon the substantially transparent head up display of a vehicle illustrating a parking aid includes monitoring a parking mode, determining the graphic illustrating the parking aid for projection upon a view of a parking surface proximate to the vehicle for display upon the substantially transparent head up display based upon the parking mode and displaying the graphic illustrating the parking aid upon the substantially transparent head up display.
US08350722B2 Identification, assessment and response to environmental conditions while in an automobile
A method is disclosed for estimating the exposure of vehicle occupants to environmental conditions capable of inducing a least discomfort. The occupants are alerted to their proximity to a zone where environmentally-challenging conditions exist and, in a first embodiment, the details of the environmental condition and the estimated duration of any exposure is communicated to the occupants; in a second embodiment a suggested course of action by which the occupants may mitigate the effect of the environmental occurrence is communicated; and in a third embodiment the proposed course of action is automatically executed subject to override by the occupants.
US08350713B2 Numerical controller having a function for determining machine abnormality from signals obtained from a plurality of sensors
Signals from a plurality of sensors (vibration sensors, temperature sensors, and humidity sensors) disposed at places on a machine are input through a communication circuit to a numerical controller that controls the machine. The numerical controller uses vibration information, temperature information and humidity information obtained from these sensors to determine whether the machine is in an abnormal state.
US08350709B2 Presence detector and occupant support employing the same
An occupant support 20 augmented with a detection system for assessing the condition of an occupant includes first and second detectors 58, 62 for detecting presence of the occupant, an occupancy detector for determining if the occupant is occupying the occupant support and an analyzer for assessing whether a presence indication from each of the first and second detectors and an occupancy indication from the occupancy detector correspond to a satisfactory condition of the occupant or an unsatisfactory condition of the occupant. A presence detection system for determining the condition of a target comprises a first and second detectors for detecting presence of the target in first and second regions, and an analyzer for assessing whether presence indications established by the presence detectors correspond to a satisfactory condition of the target or an unsatisfactory condition of the target.
US08350707B2 System, apparatus and method for automated emergency assistance with manual cancellation
A system, apparatus and method for automated emergency assistance with manual cancellation that is responsive to physiological, environmental and/or input sensors associated with an individual. In embodiments, the invention enables a sensor system or device to be biased toward what would be false alarms, which may be avoided by the individual informing the device that he or she does not need assistance. Other embodiments are described and claimed.
US08350706B2 Hygiene compliance monitoring system
A hygiene compliance monitoring system provides a dispenser that is associated with a data collection unit that collects dispensing events, such as the dispensement of material from the dispenser, which occurs during time segments of a predetermined duration. The hygiene event monitoring system also includes a portable data acquisition unit that is in wireless communication with the data collection unit of the dispenser. As such, when the data acquisition unit is brought within the range of reception of the data collection unit, the hygiene compliance data and time segment information are transmitted to the data acquisition unit and stored at a portable memory unit, which is removable. As such, the hygiene compliance data stored on the portable memory unit can be readily transferred to any desired computing device for analysis and report generation.
US08350704B2 Non-transferable radio frequency identification label or tag
A Non-transferable Radio Frequency Identification (RFID) assembly for attachment to an article comprises a RFID module; and a antenna module coupled with the RFID module, the antenna module comprising a conductive layer, a substrate, and an adhesive modification layer between the conductive layer and the substrate, the adhesive modification layer configured such that when the assembly is attached to the article and attempt to remove the assembly will cause the substrate to release and leave the conductive layer intact.
US08350700B2 System for, and method of, monitoring the movement of mobile items
A system monitors parameters (e.g., speed, position, threshold boundaries) of mobile items attached to beacons and produces signals indicating these parameters. The system also monitors non-mobile parameters (e.g., battery life, door locks, windows) in the items. Different technologies (e.g., wireless) are provided for communicating between the beacons and a beacon controller interface. Different technologies are provided for locating and indicating item positions. The beacons and the interface provide for new beacons to be added to the system with different characteristics than the existing beacons for monitoring the operation of new beacons without affecting the operation of existing beacons. The system includes resellers, retailers, users and subscribers in a flexible relationship to enhance the ease in the system operation. Beacons can perform more than one function (e.g. tracking, threshold monitoring) simultaneously. Scenarios for the beacons can be created and monitored. Recovery personnel can intervene to resolve crises.
US08350699B2 Method and system for adaptive sliding door pattern cancellation in metal detection
A metal detection device, system and method are provided. The device includes a receiver that receives a signal pattern representing electromagnetic field disturbances over time caused by movement of metal doors in a detection region. The device further includes a memory in communication with the receiver. The memory stores a recorded signal pattern of a previously received signal pattern and at least one quality criterion. The device further includes a processor in communication with the memory. The processor determines pattern vitals indicating a quality of the received signal pattern. The processor further determines whether the at least one quality criterion is met based at least in part on the pattern vitals. The processor further updates the recorded signal pattern based at least in part on determining whether the at least one quality criterion is met.
US08350697B2 Remote device control and energy monitoring by analyzing data and applying rules
Techniques are described for providing remote device (e.g., thermostat, lighting, appliance, etc.) control and/or energy monitoring. A system monitors sensor data captured by one or more sensors that sense attributes relevant to user presence at one or more monitored properties and status of one or more energy consuming devices associated with the one or more monitored properties. The system analyzes the monitored sensor data and the monitored device status with respect to a set of one or more rules and performs an operation related to controlling the one or more energy consuming devices based on the analysis of the monitored sensor data and the monitored device status with respect to the set of one or more rules.
US08350696B2 System and method for defining areas of interest and modifying asset monitoring in relation thereto
System and method for tracking assets comprises determining if an asset is inside a geofence area, using a first set of asset monitoring parameters to monitor operation of the asset, if the asset is inside the geofence area, and using a second set of asset monitoring parameters to monitor operation of the asset, if the asset is outside the geofence area. The invention further comprises a system and method for providing one or more competitors with an asset tracking device, wherein the asset tracking device allows each competitor's location to be monitored, defining one or more geofence areas on a racetrack, and detecting when the competitors enter a designated geofence area.
US08350695B2 Body coupled antenna system and personal locator unit utilizing same
A body coupled antenna system usable in a personal locator unit includes an antenna element for connection to an RF circuit; a coupling plate for conductively coupling to an adjacent body for broadening the tuning frequency and reducing the loading sensitivity; a first capacitance interconnected between the coupling plate and the antenna element; and a second capacitance interconnected between the coupling plate and the RF circuit; the first and second capacitances being set to restore a predetermined matching impedance level while maintaining the broadened tuning frequency.
US08350694B1 Monitoring system to monitor a property with a mobile device with a monitoring application
Techniques are described for providing control of a monitoring system (e.g., a home alarm or security system) using one or more mobile devices. In some implementations, a native mobile device application enables use of a mobile device as a security/automation system keypad and controller for a home security system. In these implementations, the mobile device, using the native mobile device application, checks real time status of system and sensors, arms/disarms system, turns lights on/off, looks in on live video of security cameras, reviews history of system events, reviews saved video clips, monitors/changes thermostat settings, and performs other features of a traditional security keypad in a home security system.
US08350693B2 Transmission of data to emergency response personnel
A system includes a fire extinguisher station having a number of sensors to detect various predetermined conditions that can be communicated in alarms to a central station. The central station receives alarms from the fire extinguisher and determines whether to contact emergency personnel and/or building maintenance personnel. Other items of emergency equipment can be included in the system for improved detection and response to emergency conditions.
US08350691B2 Wireless building control architecture
On a first level of the wireless building automation architecture, sensors and associated actuators communicate directly. The sensor performs control processes appropriate for the sensor and regardless of the type of actuator being used. The actuator performs control processes specific to the actuator regardless of the type of sensor being used. By direct wireless communication between sensors and actuators, the opportunity for a failed communications link using a hub and spoke arrangement may be avoided. Communication redundancy is provided by receiving the outputs of sensors at a controller, such as a controller on a second high speed or high bandwidth tier of the architecture. Regional control is implemented in the higher level tier. The higher level tier may override or control operation of components of the lower level tier as needed. The distributed control processing allows for more convenient room level integration. Where a problem is detected, such as a fire, corrective action begins within the immediate region of the sensor generating an alarm signal. The corrective action occurs without routing the alarm signal to upper levels of control processes or across different systems. The alarm signal is also propagated to upper level control systems for generating appropriate responses in other zones. To provide the different zones and avoid interference, the transmit power of the sensors and actuators is controlled as a function of two or more other devices.
US08350687B2 Gauge device
Provided is a gauge device that can provide innovativeness to representation during an operation of effect creation, and can improve the marketability and designability. A gauge device 1 is configured to include a display section 2 that displays vehicle information by rotating a pointer needle on a display panel, and an operation section 3 for use to operate various types of functions of the display section 2. Control means is also provided for operating, in response to an input of a predetermined start signal, in a cooperative manner, first illumination means 2d provided for illuminating the display section 2 and second illumination means 3c provided for illuminating the operation section 3 to make those operate a predetermined operation of effect creation. The start signal is an input of turning on or off a power switch.
US08350685B2 Collision detecting device
A collision detecting device includes a chamber member providing a chamber, a pressure sensor connected to the chamber member, and a bumper absorber absorbing an impact generated by collision of an object with the vehicle. The bumper absorber has a region, which has a thickness in a front-rear direction of the vehicle. The thickness of the region is equal to or smaller than a predetermined thickness. The region is in contact with at least a portion of the chamber member. The collision is detected based on the pressure of the chamber detected by the pressure sensor. Hereby, a collision detecting device in which the bumper absorber has sufficient rigidity, and the chamber has sufficient deformability in case of collision can be obtained.
US08350684B2 Vehicle lane departure warning system having trailer mode and method
A vehicle lane departure warning system and method are provided having a trailer mode. The system includes an imager capturing images of a roadway forward of a vehicle and an input receiving a towing signal indicative of whether the vehicle is towing a trailer. The system also includes a processor for processing the captured images and determining whether the vehicle or trailer is expected to be departing from a lane on the roadway based on the captured images and a threshold width value. The processor selects the threshold width value based on the input towing signal such that an enhanced threshold width value is employed when the vehicle is towing a trailer. An output is provided for outputting a lane departure warning signal based on the processed images and selected threshold width value.
US08350682B2 DPF warning system
A system for providing external notification of a vehicle event to an operator includes a reader device connected to a control unit providing status of at least one vehicle condition with the vehicle having a diesel particulate filter (DPF), a plurality of warning devices connected to the reader device and a power supply connected to the reader device and to the warning devices wherein the reader device receives data via data lines from the control unit, decodes the received data to determine the occurrence of a vehicle event relating to the DPF and controls ground signal lines of the warning devices to trigger at least one of the warning devices based on the detection of a particular event.
US08350677B2 System and method for integrating asset tagging with a manufacturing process
A system includes an ordering module, an asset tagging module, a database, and a manufacturer server. The ordering module is configured to receive an order for a component from a web browser. The asset tagging module is configured to receive information for an asset tag from the web browser, and to receive a selection of a location on the component to place the asset tag. The database is configured to store the order for the component, the information for the asset tag, and the location of the asset tag on the component. The manufacturer server is configured to retrieve the order for the component, the information for the asset tag, and the location of the asset tag on the component, and to direct printing of the information on the asset tag and placement of the asset tag at the location on the component prior to placing the component in packaging for the component.
US08350674B2 RFID tag including a loop antenna and RFID system using the RFID tag
An RFID tag and an RFID tag using the same are disclosed, wherein the RFID tag comprises: a circuit unit arranged on a first part of a board; and a loop type antenna on a second part of the board.
US08350672B2 Method and system for wirelessly transmitting control commands for a controller for lifting gear
Method for wirelessly transmitting control commands for a controller for lifting gear, wherein a wireless operating part has an unmistakeable address and a receiving part of the lifting gear has a selectable identifier, wherein the operating part is unambiguously assigned to a receiving part of lifting gear, said method comprising the following steps for assigning the operating part to the receiving part: (i) an address feature is formed from the address of the operating part and the identifier of the receiving part; (ii) the address feature is emitted in an allocation message; (iii) the emitted allocation message is received in the receiving part and (iv) the operating part is allocated to the receiving part, if the receiving part has not been allocated, by storing the address feature as a valid address feature in the receiving part, and corresponding system.
US08350671B2 Method and apparatus for controlling new message alert in portable wireless terminal
Provided is a method and an apparatus for controlling a NEW MESSAGE alert in a portable wireless terminal. In a sender-side terminal, a NEW MESSAGE alert is set after a message is written. The NEW MESSAGE alert setting is designated at a header of the message. The message having the header with the NEW MESSAGE alert setting is transmitted. In a receiver-side terminal, a message is received and it is determined whether a NEW MESSAGE alert is designated at a header of the received message. If a NEW MESSAGE alert is designated at the header of the received message, the designated NEW MESSAGE alert is generated. Therefore, both a sending user and a receiving user can have equal authority over the NEW MESSAGE alert.
US08350669B2 Electronic access security and keyless entry system
A system for providing secured access to and/or control of a vehicle is provided. The system includes a vehicle network such as a CAN. A remote communications device is used for sending a signal for controlling functions associated with the vehicle. There is a receiver operatively connected to the vehicle network and adapted to receive the signal from the remote communications device. At least one access module is adapted to provide control of functions of the vehicle by a user from outside of the vehicle, the access module is electrically connected to the vehicle network. There is at least one user input device associated with the access module and there are a plurality of outputs associated with the access module wherein the access module is adapted to directly control access to the vehicle through control of the plurality of outputs.
US08350665B1 RFID reader systems detecting pilot tone
RFID tags are commanded to generate a pilot tone in their backscatter. When the backscattered pilot tone is received in the reader, the pilot tone is used to estimate the tag period/frequency. Then, the estimate is used to seed and lock a symbol timing recovery loop, which provides a detected signal to one or more correlators for detecting the tag preamble. A delayed version of the received tag signal is compared against a baseline signal threshold established from the received signal to detect the pilot tone.
US08350662B2 Semiconductor ceramic and positive temperature coefficient thermistor
A semiconductor ceramic includes a BamTiO3-based composition, as a main component, having a perovskite structure represented by general formula AmBO3, wherein part of Ba constituting the A site is replaced with Na, Bi, Ca, and a rare-earth element having an ionic radius smaller than that of the Na; the content of the rare-earth element when the total number of moles of the elements constituting the A site is 1 mole is 0.0005 to 0.015 on a molar basis; and the content of the Ca when the total number of moles of the elements constituting the A site is 1 mole is 0.05 to 0.20 (preferably 0.125 or more and 0.175 or less) on a molar basis. A PTC thermistor includes a component body 1 formed of the semiconductor ceramic. Accordingly, high reliability is achieved even if an alkali metal element is present.
US08350660B2 Resin composition for filling discharge gap and electrostatic discharge protector
The present invention provides an electrostatic discharge protector capable of taking measures for electrostatic discharge against electronic wiring boards having various designs freely, simply and easily, having excellent accuracy of regulating an operating voltage and capable of being downsized and decreased on its cost, and also provides a resin composition for a discharge gap capable of preparing the electrostatic discharge protector. The resin composition for filling a discharge gap of an electrostatic discharge protector comprises a resin having a urethane structure represented by the formula (1): wherein plural R's are each independently an alkylene group of 1 to 18 carbon atoms, X is a bivalent organic group and m and n are each independently an integer of 1 to 20. The electrostatic discharge protector is obtainable by filling the discharge gap with the resin composition. The discharge gap has a width of 2 to 10 μm.
US08350656B2 Rotary transformer
A rotary transformer includes a primary core having a primary coil wound thereon, and a secondary core having a secondary coil wound thereon, the cores being mounted for relative rotation about an axis of rotation. The transformer is characterized in that one of the cores includes a plurality of core segments arranged in spaced-apart relation relative to one another in a substantially circular array about the axis, and the other core has a substantially annular configuration. In a particular embodiment, the primary core is fixed and hence remains static during operation, and includes a plurality of spaced apart core segments arranged in a circular array around the axis.
US08350654B2 Principles of the tran-energy machines
A Tran-Energy Machine is an energy conversion device to regain electric energy supplied to activated coils, from the total magnetic flux in the activated coils, and the rising and falling of magnetic flux lines of movable permanent magnets. The device may include one or more timing switches, electronic components in electric circuits, magnetic cores, permanent magnets, rotary parts, inductive coils, activation windings, rectifiers, and output switches. The one or more permanent magnets may be movably arranged with respect to the magnetic core for inducing alternating magnetic field upon movement, wherein activating and deactivating the windings attracts and repels the movable magnets generating regained energy from kinetic movement and changes in magnetic flux.
US08350653B2 Electrical connector system
The present invention relates to a connector system that provides the transfer of electrical power and/or data communications signals between two systems. The connector has no conductive electrical connection and can operate independently of angular orientation.
US08350650B2 Quadrupole magnetic coded switch
A quadrupole magnetic coded switch includes a switch housing, an actuator, one or more switch dipole magnets, and a plurality of magnetically operated switch circuits. The actuator housing is movable relative to the switch housing. The plurality of actuator dipole magnets are coupled to the actuator housing and are movable therewith. The one or more switch dipole magnets are coupled to the switch housing. The one or more switch dipole magnets and the plurality of actuator dipole magnets are arranged to generate a quadrupole magnetic field. Each magnetically operated switch circuit is disposed within the switch housing and is configured to transition between a plurality of switch positions in response to relative movement of the actuator housing and the switch housing.
US08350648B2 Power control device and assembly
A power control apparatus in the form of a standard, toggle, wall-mounted light switch for remote actuation of an electrical load or local manual override. A switch housing supports and retains a latching relay that includes power terminals, a switching terminal for remote actuation by a control signal, and a manual override. A switch lever extends from the body of the switch housing for manual actuation to override the state of the relay. The switch lever engages the manual override of the latching relay upon manual actuation by a person. A centering structure maintains the switch lever in a centered position to allow unimpeded movement of the manual override. The latching relay can be remotely actuated by a signal at its switching terminal to switch a power load connected to the power terminals on or off, or the relay can be manually overridden by actuation of the switch lever.
US08350647B2 Electromagnetic contact device
A plurality of terminal chambers (20a) to (20e) is formed in a housing (16) by using a plurality of partition walls (24a) to (24e) to partition. In the terminal chambers, fixed contactors (31) each having a fixed contact point (31d) and a terminal screw (31a) are mounted. Engaged portions (31b) are formed integrally with the fixed contactors. Further, a press-fit engaging portion (26) is provided in each of the terminal chambers. The terminal chamber is formed as a space different from a space accommodating a movable contact point support, and the press-fit engaging portion is engaged by the engaged portion by press-fitting.
US08350646B2 Connection structure of the armature and the pushing mechanism of the relay
A connection structure of an armature and a pushing mechanism of a relay has an armature and a pushing block. The head of the armature is T-shaped and connected by a vertical arm and a cross arm. One end of the pushing block has a bar-shaped through hole and a bar-shaped blind hole, disposed alongside and vertical to the motion direction of the pushing block. A through groove to connect the bar-shaped trough hole and the blind hole is disposed at the centre of the bar-shaped through hole and the blind hole. With the through groove, the T-shaped armature head can move along the through groove when the T-shaped armature head is shoved into the bar-shaped through hole. The cross arm of the T-shaped armature head is dropped into the bar-shaped blind hole to cooperate with the bar-shaped blind hole to drive the pushing block when the armature swings.
US08350644B2 Band pass filter combiner
A band pass filter combiner carrying a broadband signal with a central frequency comprises a power divider, a high pass band filter, a low pass band filter, and a power combiner. The distance from the signal input port of the power divider to each of signal input ports of the high pass band filter and the low pass band filter is equal to a quarter of the wavelength at the central frequency. The distance from each of signal output ports of the high pass band filter and the low pass band filter to the signal output port of the power combiner is also equal to a quarter of the wavelength at the central frequency.
US08350641B2 Band selective isolation bridge for splitter
A splitter device includes a first splitter comprising an input leg coupled to a provider content input port, a first output leg, and a second output leg. The provider content input port is configured to receive a downstream-propagating provider bandwidth. The splitter device further includes a first conductive path coupled to the first output leg of the first splitter, and a second conductive path coupled to the second output leg of the first splitter. The splitter device further includes a second splitter having an input leg coupled to a first home network bandwidth, a first output leg coupled to the first conductive path, and a second output leg. The splitter device further includes a third splitter having an input leg coupled to a second home network bandwidth, a first output leg coupled to the second conductive path, and a second output leg. The splitter device further includes a bridge circuit operatively coupled between the first conductive path and the second conductive path. The bridge circuit is configured to propagate a home network bandwidth from the first user port to the second user port and isolate the provider bandwidth from the home network bandwidth.
US08350640B2 Transceiver module for satellite antenna
A transceiver module for a satellite antenna comprises a base and a cover. The base includes a transducer extending between a first end plate and a second end plate in a first direction, a first filter portion including a number or first grooves extending in the first direction and arranged along a second direction orthogonal to the first direction, and a waveguide to guide signals toward a third end plate. The cover serves as a second filter portion for the transceiver module and includes a number of second grooves arranged along the second direction. The base includes the transducer, the first filter portion and the waveguide as an integral member.
US08350638B2 Connector assembly for providing capacitive coupling between a body and a coplanar waveguide and method of assembling
A connector assembly includes, but is not limited to, a body having a top side and a bottom side. A bottom signal plate is connected to the bottom side and is configured for capacitive coupling to a conductor of a coplanar waveguide. A bottom grounding plate is connected to the bottom side and is spaced apart from the bottom signal plate. The bottom grounding plate is configured for capacitive coupling to a grounding plane of the coplanar waveguide. A first electrically conductive pathway is electrically connected to the bottom signal plate and extends to the top side. A second electrically conductive pathway is electrically connected to the bottom grounding plate and extends to the top side. A dielectric adhesive at least partially covers a bottom portion of the connector assembly.
US08350637B2 Circuit substrate including a plurality of signal lines and ground lines forming a 3-D grounding circuit loop
A circuit substrate includes a first pair of ground lines, a second pair of ground lines, a plurality of first connection lines, a plurality of second connection lines and a plurality of conductive pillars. The first and second pairs of ground lines are located on first and second surfaces of the substrate, respectively. The pillars are located in the substrate and vertically conducted between the first pair of ground lines and the second connection lines and between the second pair of ground lines and the first connection lines, and the first and second pairs of ground lines are conducted, so that a 3-D grounding circuit loop is formed. Moreover, a first pair of signal lines is disposed between the first connection lines for grounding and a second pair of signal lines is disposed between the second connection lines for grounding to get a better signal integrity.
US08350636B2 Modulation arrangement and method for providing a modulated control signal
A modulation arrangement comprises an input (E) for supplying a data signal (DS), a pre-modulator (VMod) that is coupled to the input (E) and features a clock pulse input (TEV) for supplying a pre-clock pulse (VT), a main modulator (HMod) that is coupled to the pre-modulator (VMod) on the input side and comprises a clock pulse input (TEH) for supplying a main clock pulse (HT), as well as an output for providing a modulated control signal (ST), and a switchable current source (Q, S) for providing a current (IS) that is controlled by the modulated control signal (ST) at an output (A) of the modulation arrangement. Furthermore, a method for providing a modulated control signal is disclosed.
US08350633B1 Microelectromechanical resonators with passive frequency tuning using variable impedance circuits
Periodic signal generators include an oscillator circuit, which is configured to generate a first periodic signal at an output thereof, and a piezoelectric-based microelectromechanical resonator. The resonator is configured to generate a second periodic signal at a first electrode thereof, which is electrically coupled to the oscillator circuit. A variable impedance circuit is provided, which is electrically coupled to a second electrode of the piezoelectric-based microelectromechanical resonator. The variable impedance circuit is configured to passively modify a frequency of the second periodic signal by changing an induced electromechanical stiffness in at least a portion of the piezoelectric-based microelectromechanical resonator.
US08350629B2 Differential resonant ring oscillator utilizing magnetically tuned YIG resonators to achieve ultra low phase noise and multi-octave electronic tuning in microwave frequencies
A differential resonant ring oscillator (“DRRO*) circuit using a ring oscillator topology to electronically tune the oscillator over multi-octave bandwidths. The oscillator tuning is substantially linear, because the oscillator frequency is related to the magnetic tuning of a YIG sphere, which has a resonant frequency equal to a fundamental constant multiplied by the DC magnetic field. The simple circuit topology uses half turn or multiple half turn loops magnetic coupling methods connecting a differential pair of amplifiers into a feedback loop configuration having a four port YIG tuned filter, thus creating a closed loop ring oscillator. The oscillator may use SiGe bipolar junction transistor technology and amplifiers employing heterojunction bipolar transistor technology SiGe is the preferred transitor material as it keeps the transistor's 1/f noise to an absolute minimum in order to achieve minimum RF phase noise.
US08350628B1 Gate speed regulator dithering ring oscillator to match critical path circuit
A computing device is disclosed comprising digital circuitry including a critical path circuit, and a gate speed regulator. A ring oscillator generates an oscillation frequency, and dither circuitry periodically adjusts a number of inverter elements in the ring oscillator in order to adjust an average propagation delay of the ring oscillator relative to a propagation delay of the critical path circuit. A comparator compares the oscillation frequency to a reference frequency to generate an error signal, and an adjustable circuit, responsive to the error signal, adjusts at least one of a supply voltage and a clocking frequency applied to the digital circuitry.
US08350623B2 Variable gain amplifier
An apparatus and method are provided. Generally, an input signal is applied across a main path (through an input network) and across a cancellation path (through a cancellation circuit). The cancellation circuit subtracts a cancellation current from the main path as part of the control mechanism, where the magnitude of the cancellation current is based on a gain control signal (that has been linearized to follow a control voltage).
US08350621B2 Analog circuit and semiconductor device
An object is to obtain a semiconductor device having a high sensitivity in detecting signals and a wide dynamic range, using a thin film transistor in which an oxide semiconductor layer is used. An analog circuit is formed with the use of a thin film transistor including an oxide semiconductor which has a function as a channel formation layer, has a hydrogen concentration of 5×1019 atoms/cm3 or lower, and substantially functions as an insulator in the state where no electric field is generated. Thus, a semiconductor device having a high sensitivity in detecting signals and a wide dynamic range can be obtained.
US08350620B2 Integrated circuit power consumption calculating apparatus and processing method
An integrated circuit power consumption calculating apparatus obtains power consumption of an integrated circuit by outputting circuit component transistor connection information of each of circuit components after setting a group of transistors connected via a source terminal/drain terminal of a transistor within each cell of an integrated circuit, by outputting circuit component logic model information after extracting a logic for each of the circuit components from the circuit component transistor connection information information, by obtaining power information (circuit component power information) of each signal transition state of an input/output terminal for each of the circuit components based on the circuit component transistor connection information information, by generating signal terminal transition information with a logic simulation performed for each of the circuit components of the integrated circuit, and by obtaining power consumption in a signal transition of an input/output terminal of each of the circuit components.
US08350616B1 Variable output charge pump circuit
A drive frequency source with two selectable output frequencies connected to two charge pump arrays. A first array of basic charge pump units is connected to the first output frequency and a second array of basic charge pump units is connected to the output frequency. One or more of the basic charge pump units making up the aforementioned first and second charge pump arrays has an enable input allowing its output current contribution to be added or subtracted from the total array output. The output of the first array is coupled to a P-type substrate and the output of the second array is coupled to an N-well residing in the P-type substrate. A controller may be coupled to the drive frequency source for selecting the output frequencies, and an output monitor may be coupled between the array outputs and the controller to provide feedback.
US08350614B2 Analog logic automata
A distributed, reconfigurable statistical signal processing apparatus comprises an array of discrete-time analog signal processing circuitry for statistical signal processing based on a local message-passing algorithm and digital configuration circuitry for controlling the functional behavior of the array of analog circuitry. The input signal to the apparatus may be expressed as a probabilistic representation. The analog circuitry may comprise computational elements arranged in a network, with a receiving module that assigns probability values when an input signal arrives and communicates the probability values to one of the computational elements, the computational elements producing outputs based on the assigned probability values. The signal processing apparatus may be an analog logic automata cell or an array of cells, wherein each cell is able to communicate with all neighboring cells.
US08350611B1 Bandgap circuit and start circuit thereof
A start circuit including a load unit, a first switch, a second switch and a reset control circuit is provided. The load unit receives a power voltage. The first switch is electrically connected between a first end of the load unit and a ground, and receives a node voltage from a reference circuit. The second switch has a first end electrically connected to the reference circuit, a second end electrically connected to the ground, and a control end electrically connected to the second end of the load unit. The second switch determines whether to provide a start voltage to the reference circuit according to a conducting state thereof. The reset control circuit provides a discharge path between a control end of the first switch and the ground, and conducts the discharge path according to the power voltage during a period when the power voltage is smaller than a threshold voltage.
US08350609B2 Semiconductor device
The present invention provides a semiconductor device in which an adjustable range of a resistance value of a variable resistance circuit is large. The semiconductor device has an output buffer including a plurality of sets of resistance elements and a plurality of sets of transistors, a plurality of replica circuits, and a plurality of sets of operational amplifiers, and drain currents of the plurality of sets of transistors are adjusted so that output impedances of the output buffer become predetermined values. Therefore, even in the case where the resistance values of the resistance elements largely fluctuate due to fluctuations in manufacture process and the like, the output impedances can be set to predetermined values.
US08350607B2 System and method for an accuracy-enhanced DLL during a measure initialization mode
A clock generator having a delay locked loop and a delay control circuit. The delay locked loop receives an input clock signal and adjusts an adjustable delay circuit to generate an output clock signal that is synchronized with received input clock signal. The delay control circuit coupled to the delay locked loop generates a control signal to initialize the delay measure operation to adjust the adjustable delay circuit, after comparing the phase difference of the input clock signal and the output clock signal. The delay control circuit further generates a start measure control signal to start measuring a delay applied to the measurement signal propagating through the adjustable delay circuit, and generates a stop measure control signal to stop the delay measurement of the measurement signal. The delay adjustment of the delay locked loop is then adjusted to apply the delay measurement when synchronizing the input and output clock signals.
US08350601B2 Device for driving switching elements
A drive unit controls the operation of a corresponding power switching element such as IGBT which forms an inverter and a converter. The drive unit controls the operation of the corresponding power switching element to supply an operation current to a motor generator. First and second switching elements in the drive unit are simultaneously turned on when an operation signal transferred from a control device is switched to a turning-on instruction operation signal. The voltage at the gate terminal of the power switching element is shifted to a divided voltage obtained by dividing a voltage of the power source by first and second resistances connected in series in the drive unit. When a mirror time period of the power switching element is elapsed, the second switching element only is turned off in order to shift the gate voltage of the power switching element to the voltage of the power source.
US08350600B2 Glitchless clock multiplexer controlled by an asynchronous select signal
A glitchless clock multiplexer controlled by an asynchronous select signal for use in GPS receivers is disclosed. A device in accordance with the present invention comprises a device for producing a clock signal, the clock signal being selected from a plurality of asynchronous frequency sources. A device in accordance with the present invention comprises a first frequency source, a second frequency source, a select signal, wherein the select signal is asynchronous with the first frequency source, and a multiplexer, which receives the first frequency source and the second frequency source, wherein the multiplexer selects as an output of the multiplexer one of the first frequency source and the second frequency source based on a value of the select signal, such that when the multiplexer switches between the first frequency source and the second frequency source, and between the second frequency source and the first frequency source, the transition is performed when the output of the multiplexer is at a logic low.
US08350598B2 Multi-stage receiver
A multi-stage receiver comprises an input stage, an intermediate stage, and an output stage. The input stage is configured to provide a first signal and a second signal. The intermediate stage is coupled to the input stage and comprises a first amplifying circuit and a second amplifying circuit. Positive and negative input terminals of the first amplifying circuit receive the first signal and the second signal, respectively. Positive and negative input terminals of the second amplifying circuit receive the second signal and the first signal, respectively. The output stage is coupled to the intermediate stage and configured to generate low-skewed differential signals according to output signals of the intermediate stage.
US08350591B2 Configurable IC's with dual carry chains
A configurable integrated circuit (“IC”) that includes several configurable tiles, each of which has a set of configurable logic circuits and a set of configurable routing circuits for routing signals between configurable logic circuits. The configurable IC provides a set of associated configurable logic circuits for performing a particular portion of a larger arithmetic operation. The configurable IC provides a carry circuit for generating a carry out signal for the particular portion of the larger arithmetic operation. A configurable storage element is for configurably storing the carry out signal and for providing the stored carry out signal to the carry circuit for performing a subsequent portion of the larger arithmetic operation. The configurable IC provides a configurable interconnect/storage element for configurably routing a carry signal from a first carry chain to a second carry chain and for storing the routed carry signal.
US08350588B2 Deactivation of integrated circuits
Integrated circuits and methods of permanently disabling integrated circuits are disclosed. An integrated circuit having an erasable non-volatile memory adapted to store an activation code and logic to disable the integrated circuit when the code in the erasable non-volatile memory has been altered or erased after it has been separated from a substrate, is placed into an electromagnetic field of sufficient power to erase or reprogram the erasable non-volatile memory. The entire integrated circuit is permanently disabled by erasing, altering, or reprogramming the erasable non-volatile memory. In preferred embodiments, the integrated circuit comprises a non-erasable non-volatile memory storing the activation code, and circuitry adapted to permanently disable the integrated circuit when the code in the erasable non-volatile memory does not match the activation code in the non-erasable non-volatile memory. Erasing, altering, or reprogramming the erasable non-volatile memory results in a mismatch of the non-volatile memories, which permanently deactivates the integrated circuit.
US08350587B2 Reversing the weak measurement on a qubit
Methods and systems are disclosed for restoring a state of a qubit transformed by a weak measurement to its original state. Unlike traditional methods, in which, the restoration was carried out by way of another weak measurement, the disclosed method uses an additional qubit, referred to as the ancillary qubit, and appropriate Hadamard and CNOT transformation for restoring the original state. Because the disclosed method avoids a second weak measurement, the time for restoration of the original state is considerably reduced.
US08350586B2 Method and apparatus of deembedding
Provided is a method of de-embedding. The method includes forming a test structure having a device-under-test embedded therein, the test structure having left and right pads coupling the device-under-test, the device-under-test dividing the test structure into left and right half structures, the left and right half structures each having intrinsic transmission parameters; forming a plurality of dummy test structures, each dummy test structure including a left pad and a right pad; measuring transmission parameters of the test structure and the dummy test structures; and deriving intrinsic transmission parameters of the device-under-test using the intrinsic transmission parameters of the left and right half structures and the transmission parameters of the test structure and the dummy test structures.
US08350574B2 Circuit for detecting malfunction generation attack and integrated circuit using the same
An embodiment of the invention provides a circuit for detecting a malfunction generation attack, including: at least one sensor circuit adapted to detect a radiation of a light; and a detection circuit for detecting an intermediate voltage between a voltage corresponding to a High level and a voltage corresponding to a Low level in accordance with an output from the at least one sensor circuit, and outputting a detection signal. At least one sensor circuit has an output node a level at which is changed in accordance with the radiation of the light, and outputs a signal corresponding to the level at the output node which is changed in accordance with the radiation of the light. The detection circuit outputs the detection signal when a level of the output signal from the at least one sensor circuit reaches a level previously set.
US08350570B2 Pipe survey method using UWB signal
A method of surveying the condition of an underground enclosure including the steps of (a) positioning at least one transmitter/receiver unit (including an antenna) within an underground, substantially nonconductive enclosure, such that a substantial air gap exists between the antenna and the inner wall of the enclosure; (b) transmitting an ultra wideband (UWB) signal toward at least a portion of the inner wall; and (c) processing the return signal in order to identify the interface between the soil and a region of conductivity different from the soil.
US08350569B2 Device and method for switching a pin diode
A circuit for switching a PIN diode has a PIN diode and an inductor (in particular a coil) as well as a direct voltage source and a group of switches, wherein in a first switch setting of the group of switches the PIN diode can be fed with current from the direct voltage source in its admission direction; and in a further switch setting the PIN diode and the inductor are separated from the direct voltage source and are arranged in a closed current loop such that the inductor can generate a discharge current upon transitioning to the further switch setting, which discharge current is directed to the PIN diode opposite to the current generated by the direct voltage source (DC).
US08350568B2 Nuclear magnetic resonance apparatus
A nuclear magnetic resonance apparatus includes a dewar containing a low-temperature liquid refrigerant, a prepolarization coil disposed inside the dewar and including a superconducting wire, a prepolarization coil driving unit for intermittent application of current to the prepolarization coil in a capacitor charge/discharge method to generate a prepolarization magnetic field, a sensor unit for measuring a nuclear magnetic resonance signal from a sample to which a prepolarization magnetic field is applied with the prepolarization coil, and a readout magnetic field generation unit for applying a readout magnetic field to the sample.
US08350567B2 Pre-adjustable SMD coils for high currents
In a device and method to install a coil in a circuit, the coil is installed on a substrate and the inductance value of the coil installed on the substrate is adjusted with a test circuit board. The substrate is then installed in the circuit. This enables an efficient installation of the coil.
US08350566B2 Magnetic particle imaging apparatus, method of disposing detection coil for magnetic particle imaging apparatus, and magnetic flux detecting apparatus
In a magnetic particle imaging apparatus that forms an image of a distribution of magnetic particles based on changes in a magnetic flux generated by magnetization of the magnetic particles, modulation coils that magnetize magnetic particles present in a field free area by applying a modulation magnetic field to the field free area, and detection coils are disposed such as to suppress an influence caused by a magnetic flux of the modulation magnetic field applied by the modulation coils and included in a detected magnetic flux.
US08350563B2 Magnetic field sensor and method used in a magnetic field sensor that adjusts a sensitivity and/or an offset over temperature
A magnetic field sensor and a method associated with the magnetic field sensor provide gain correction coefficients and/or offset correction coefficients stored in the magnetic field sensor in digital form. The gain correction coefficients and/or offset correction coefficients can be used to generate analog control signals to control a sensitivity and/or an offset of an analog signal path through the magnetic field sensor.
US08350559B2 Position detection apparatus and sensor unit
A position detection apparatus includes a position pointer having a coil and a sensor unit for detecting the position of the position pointer. The sensor unit has a sensor board including a plurality of loop coils juxtaposed and extending in a predetermined direction, and the sensor unit detects a signal generated in the loop coils by electromagnetic induction between the coil of the position pointer and the loop coils, to thereby detect the position of the position pointer. The sensor unit further includes a shield member disposed on the sensor board remotely from the position pointer for reducing noise, and a magnetic path sheet formed from a plurality of magnetic path members of a substantially rectangular shape having a higher magnetic permeability than that of the shield member and disposed between the sensor board and the shield member. The magnetic path members have mutually contacting portions disposed in an inclined relationship by a predetermined angle relative to said predetermined direction of the sensor board.
US08350552B1 Voltage reference and temperature sensor
A highly accurate voltage reference and temperature sensor circuit requires only several low-cost components in addition to a general-purpose microcontroller with an analog-to-digital converter. Unlike known circuits, the circuit disclosed does not rely on matching between a pair of semiconductor devices, as only a single semiconductor junction is used. All of the signal processing may be performed digitally.
US08350551B2 Power-supply controller
An embodiment of a power-supply controller includes a signal combiner and a control circuit. The signal combiner is operable to generate a combined feedback signal from sense and output feedback signals that are respectively derived from a sense signal and a regulated output signal, and the signal combiner is operable to receive the sense signal from a sense circuit that is operable to generate the sense signal while a current is flowing through an inductor and while a switch that is disposed between the inductor and an input voltage has a first state. The sense signal generated by the sense circuit is related to the current, and the switch and the inductor are operable to generate the regulated output signal. The control circuit is coupled to the signal combiner and is operable to cause the switch to have a second state for a predetermined time in response to the combined feedback signal having a predetermined relationship to a reference signal.
US08350547B2 DC to DC converter
A DC to DC converter includes an input terminal, an output terminal, first and second switches, an inductor, a smoothing unit, a first impedance element, a first resistor element, an operational amplifier and a control unit. The first switch is connected to the input terminal. The second switch is connected to the first switch and a ground terminal. The inductor is connected to the first switch and the output terminal. The smoothing unit is connected to the inductor and the ground terminal. The first impedance element is connected to the smoothing unit. The first resistor element is connected in series with the first impedance element. The operational amplifier is connected to the first impedance element. Reference voltage is added to the operational amplifier. The control unit controls the first and second switches according to a control signal outputted from the operational amplifier.
US08350545B2 Current balancer
A current balancer suitable for a multi-phase power converting device is provided. The current balancer includes an error detection unit and a plurality of pulse control units. Each of the pulse control units includes a current-to-voltage converter, a charging and discharging controller, a capacitor, and a comparator. The error detection unit detects a plurality of channel currents generated by the multi-phase power converting device, and generates a plurality of error currents by calculating. The charging and discharging controller provides a charging voltage or a discharging voltage according to a constant pulse-width modulation (PWM) signal. When the channel currents are balanced, the comparator generates a PWM signal with a constant duty cycle. When the channel currents are not balanced, an error voltage generated by the current-to-voltage converter is used to adjust a voltage level of the charging voltage or the discharging voltage, so that the PWM signal is varied correspondingly.
US08350544B2 Voltage conversion device capable of enhancing conversion efficiency
A voltage conversion device capable of enhancing conversion efficiency includes a charge pump for generating output voltage linear to input voltage according to the input voltage, a feedback unit for generating a feedback signal according to the output voltage generated by the charge pump, and a regulating unit for outputting and adjusting the input voltage according to the feedback signal provided by the feedback unit, so as to keep the output voltage unchanged.
US08350541B2 Control circuit and method for a soft-start scheme of a switch mode power supply for a power amplifier
There is provided a control circuit including a sampling controller configured to sample an output voltage of a power converter at an appropriate time slot by opening a control loop. A soft-start circuit configured to enable soft-starting of an internal soft-start reference voltage to start from the sampled output voltage and to control the internal soft-start reference voltage to a predetermined target value in order to pre-charge the output voltage close to an input voltage level, or to continue charging the output voltage to a predetermined output voltage value.
US08350540B2 Storageless step-down switching DC-DC converter
A storageless DC-DC converter is provided having simultaneously ultra high efficiency of 99.5% in an ultra compact size leading to 1 kW/inch3 power density, while also providing a regulation over the wide input DC voltage range. In addition to fixed 2 to 1 step-down voltage conversion the continuous output voltage reduction is obtained by use of a new method of the modulation of the freewheeling time of one of the two current rectifiers. This provides a simple regulation of the output voltage via a standard duty ratio control, despite the wide range of the input voltage change and simultaneous wide range of the load current change. An alternative control method customarily used in classical resonant converters to control output voltage by change of the switching frequency with a fixed duty ratio control is also demonstrated. Because of its storageless feature and continuous output voltage regulation this converter is ideal for computer applications, such as VRM (Voltage Regulator Modules), demanding extremely fast transient response to fast load current changes and tight load voltage regulations requiring ultra low output ripple voltages.
US08350539B2 Frequency modulation control of a buck-boost power converter
A control circuit and method are proposed to generate a control signal to operate a buck-boost power stage of a buck-boost power converter to convert an input voltage to an output voltage. The control circuit and method detect the output voltage to generate an error signal, control the frequency of two ramp signals according to the error signal, generate two pulse width modulation signals according to the error signal and the two ramp signals, and generate the control signal according to the two pulse width modulation signals. When the loading of the buck-boost power converter transits from heavy to light, the frequency of the two ramp signals is decreased to improve the efficiency of the buck-boost power converter. The peaks and valleys of the two ramp signals may be adjusted by signals related to the input voltage and the output voltage.
US08350538B2 Voltage step-down switching DC-to-DC converter
A number of non-isolated and isolated converter embodiments are disclosed all featuring the three switches and characteristic not present in prior-art converters such as: a) reduced voltage stresses on all three switches resulting in safe operation without a danger of voltage overstress of any of the three switches over the full operating range from duty ratio of 0 to 1.0 and thus resulting in wide input voltage operating. b) operating range with magnetics flux and magnetic size much reduced compared to prior-art converters c) stressless switching eliminates switching losses and reduces stresses which are present in prior-art converters. All three features result in simultaneous increase of efficiency, reduction of size and cost when compared with prior-art converters.
US08350534B2 Method and electronic circuit for efficient battery wake up charging
A method for efficiently charging a battery. The method includes producing a first signal having a voltage level dependent on the voltage of the battery, comparing the voltage level of the first signal with a settable voltage representative of a maximum battery charging current, and producing a second signal representative of a charging current to be provided to the battery, the second signal having a voltage level selected to be the lower voltage level between the first signal and the settable voltage.
US08350532B2 Power management systems
A power management system includes a first switch, a second switch, and a controller coupled to the first and second switches. The first switch has a first transfer terminal. The second switch has a second transfer terminal. The controller controls power conversion by turning on a third switch periodically. The first and second transfer terminals and a third transfer terminal of the third switch are coupled to a common node. The resistance between the first transfer terminal and the common node, the resistance between the second transfer terminal and the common node, and the resistance between the third transfer terminal and the common node are substantially equal to zero.
US08350530B2 Aircraft battery charging system having two voltage regulators
An aircraft battery charging system having an alternator with a rotatably driven field coil and a stator coil in which the stator coil is connected to a voltage output from the alternator. The system includes a power source, a first voltage regulator and a second voltage regulator. A switch mechanism selectively connects one of the first or second voltage regulators to one end of the field coil.
US08350528B2 Battery pack and balancing method of battery cells
A balancing method for a battery pack includes balancing battery cells near an end of discharge. A deep discharge of the battery cells can be prevented without using an overdischarge control unit. One battery cell balancing method includes: a balancing check condition determination step for determining whether or not a maximum voltage out of voltages of the battery cells is smaller than a reference voltage; a balancing start condition determination step for determining whether or not a residual capacity difference or voltage difference between the individual battery cells exceeds a reference value; a balancing time calculation step for calculating a balancing time for discharging the battery cell that exceeds the reference value; and a balancing operation step for discharging the selected battery cell when the battery cells are under charge or are at rest or when a discharge current of the battery cells is smaller than a reference current.
US08350523B2 Charging system with galvanic isolation and multiple operating modes
Systems and methods are provided for operating a charging system with galvanic isolation adapted for multiple operating modes. A vehicle charging system comprises a DC interface, an AC interface, a first conversion module coupled to the DC interface, and a second conversion module coupled to the AC interface. An isolation module is coupled between the first conversion module and the second conversion module. The isolation module comprises a transformer and a switching element coupled between the transformer and the second conversion module. The transformer and the switching element are cooperatively configured for a plurality of operating modes, wherein each operating mode of the plurality of operating modes corresponds to a respective turns ratio of the transformer.
US08350516B2 Electric motor drive device and method of controlling the same
A control device controls a switching operation of a switching element such that an AC voltage allowing an AC motor to output torque in accordance with a torque command value is applied to a coil winding of each phase. The control device sets a gate resistance variably between a first pulse voltage at the time of reversal of polarity of the AC voltage and a remaining pulse voltage, in a drive circuit for turning on/off the switching element in response to a switching control signal. By making longer a time period for the first pulse voltage at the time of reversal of polarity to rise, occurrence of partial discharge in a gap between coil windings of respective phases is suppressed.
US08350512B2 Electric power tool
An electric power tool is provided that includes a motor as a driving source, a first operation switch, a first semiconductor switch, and a second semiconductor switch. The first operation switch is operated by a user to be turned ON/OFF. The first semiconductor switch, provided on a current path from the power source to the motor, includes at least one semiconductor switching device. When the first operation switch is OFF, the first semiconductor switch is turned OFF to interrupt the current path. When the first operation switch is ON, the first semiconductor switch is turned ON to close the current path. The second semiconductor switch is provided on the current path in series with the first semiconductor switch and includes at least one semiconductor switching device. The second semiconductor switch closes/interrupts the current path by being turned ON/OFF in accordance with an input control signal.
US08350509B2 Power switching system including a micro-electromechanical system (MEMS) array
A switching system includes a plurality of diodes forming a diode bridge, and a micro-mechanical system (MEMS) switch array closely coupled to the plurality of diodes. The MEMS switch array is electrically connected in an (M×N) array. The (M×N) array includes a first MEMS switch leg electrically connected in parallel with a second MEMS switch leg. The first MEMS switch leg includes a first plurality of MEMS dies electrically connected in series, and the second MEMS switch leg includes a second plurality of MEMS dies electrically connected in series.
US08350505B2 Method for ascertaining a correction value for the angle of the rotor of an electrically commuted reversible synchronous motor
An electrically commuted reversible synchronous motor is activated in a calibration journey using an externally forced rotating field, during which an electrical angle of a rotating field and a mechanical angle of the rotor are measured simultaneously at a reference position by an external sensor. These items are stored associated with one another as a measurement series of value pairs. The electrical angle of the rotating field and the mechanical angle of the rotor are also detected simultaneously after direction reversal of the rotating field. These are stored as a second measurement series of value pairs. The angle difference between the electrical angle and the mechanical angle are calculated from value pairs of both measurement series. The correction value for taking the actual incorrect angle into consideration is calculated from the two angle differences by averaging.
US08350502B2 Electromagnetic motor
An electromagnetic motor having a frame, and at least one disc rotatably mounted to the frame. At least one permanent magnet is mounted on the disc, and at least one electromagnet is mounted to the frame in magnetic proximity to the at least one permanent magnet. A battery is electrically coupled to the motor for powering the at least one electromagnet. A switch controls electrical power between the battery and the at least one electromagnet, and a sensing means is provided for controlling the switch to activate the at least one electromagnet with respect to the at least one permanent magnet to cause the at least one disc to rotate. Preferably, a generator is mechanically coupled to the motor and electrically coupled to the battery for generating electrical power to the battery, and a renewable energy source such as a photovoltaic cell is electrically coupled to the motor to supplement any net electrical loss.
US08350501B2 DC/DC bridge
DC/DC bridge for controlling a direct-current load (M1), which bridge is provided with controllable semiconductor switches (S11-S14, S21-S26) and with a control unit (BC1). The bridge comprises two bridge sections (B11, B12), at least the first bridge section (B11) of which is controlled with pulse-width modulation (PWM) to regulate the current magnitude, and which bridge comprises a determination of the current of the direct-current load (M1). The second bridge section (B12) conducts direct current when the determined value (2) of the current of the direct-current load differs from zero by more than the limit value (1) of the current.
US08350496B2 Method and apparatus for driving a pulse modulated output circuit
Light Emitting Diodes (LEDs) are increasingly used in illumination applications. To control multiple Light Emitting Diodes (LEDs), or any other controllable light source, this document introduces a single-wire multiple-LED power and control system. Specifically, individually controlled LED units are arranged in a series configuration that is driven by a control unit located at the head of the series. Each of the individually controlled LED units may comprise more than one LED that is also individually controllable. The head-end control unit provides both electrical power and control signals down a single wire to drive all of the LED units in the series in a manner that allows each LED unit to be controlled individually or in assigned groups.
US08350490B2 Crop lighting
A method and lighting installation for use in horticulture for lighting crops in a greenhouse, with a number of lamps (2a . . . 2n) provided above the crops to be lighted, and a number of dimmer devices (4a . . . 4n) for the lamps, wherein the dimmer devices (4a . . . 4n) are provided with control means for periodically, automatically, varying the light intensity of the light sources cooperating with the dimmer devices according to a predetermined pattern.
US08350488B2 Integrated backlight control system
A lighting arrangement constituted of: a power factor correction circuit; a lighting controller operative at an electrical potential consonant with the electric potential of the output of the power factor correction circuit; a switching network, coupled to the output of the power factor correction circuit and to respective outputs of the lighting controller; a transformer, a primary winding of the transformer coupled to the output of the switching network; and at least one luminaire coupled to at least one secondary winding of the transformer and arranged to be driven by the at least one secondary winding, the lighting controller operative to control the switching network via the respective outputs to switchably pass current from the power factor correction circuit through the primary winding, thereby powering the at least one luminaire.
US08350487B2 Switch circuit
A switch circuit, particularly suitable for dimmer switches, detects zero-crossing or similar points in the supply and uses those to make predictions of future zero-crossing occurrences. The predicted occurrences may be used to time the operation of the switch itself to chop the supply which results in less variation in the power supplied (flicker if the switch circuit is operating a lamp) since the positions of the measured zero-crossings can be subject to noise but flicker is reduced if the switch is operated at times with respect to the true supply waveform. The predicted times may be obtained from a local oscillator having a period set by, for example, low pass filtering the period of the measured zero-crossings. The phase of the oscillator may be adjusted such that an error between the predicted and measured zero-crossings is reduced.
US08350484B2 Push button switch
A push button switch for use in logic-level switching applications. It has dual-intensity LED backlighting of a display: the switch off-state is low intensity and the on-state is distinctly brighter. The button assembly, not attached to the main body, uses magnets to provide a tactile touch and a retaining force. The backlight power is inductively coupled to the button assembly by a high-frequency oscillator that also limits and controls the LED backlight current. Switching is by a Hall-effect switch; alternate action is by bistable logic; and diode logic provides single-wire switch output and remote-control input. The wire can also carry remotely generated pulse signals to program an alternative active display. There are no mechanisms or wear parts in the assemblies, allowing impregnation sealing.
US08350483B2 Light-emitting element driving circuit
A light-emitting element driving circuit includes a PWM signal output circuit configured to output a plurality of PWM signals each having one logic level whose duty ratio corresponds to gradation data and each corresponding to each of a plurality of light-emitting elements, on the basis of the gradation data indicating brightness of each of the plurality of light-emitting elements. A driving signal output circuit is configured to change the duty ratio of each of the plurality of inputted PWM signals to output the plurality of changed PWM signals as a plurality of driving signals, on the basis of instruction data for changing the brightness of the plurality of light-emitting elements. A driving circuit is configured to drive the plurality of light-emitting elements on the basis of a duty ratio of each of the plurality of driving signals.
US08350481B1 Method of creating a light effect
A method of creating a light effect using the concurrent exposure of a variety of colored designs to at least two different colored light emitting diode lights and controlling the light emitting diode lights.
US08350480B2 Plasma lamp using a shaped waveguide body
A plasma lamp for an electrodeless plasma lamp having a shaped dielectric waveguide body. The shaped body may have a relatively thin region containing a bulb, and a second region thicker than the first region. Microwave probes may be positioned in the second region to provide power to the waveguide body. The body may be shaped to intensify the electric field in the first region adjacent to the bulb to allow operation at a lower frequency than a solid cylindrical or rectangular waveguide body having the same volume and dielectric constant.
US08350475B2 High-pressure gas discharge lamp for a lighting device
The invention relates to a high-pressure gas discharge lamp (8) for a lighting device, in particular for a headlight unit of a motor vehicle, with an electronic ignition system (9) that is arranged inside a lamp cap housing (1, 2) that comprises an upper part (1) and a cover (2), wherein said upper part (1) is provided with an opening (1.1) within which a high-voltage connection (4) between the high-pressure gas discharge lamp (8) and the electronic ignition system (9) is present, the cover (2) projects into said opening (1.1) and closes off this opening (1.1) in an insulating manner, and the mutually facing surfaces of the upper part (1) and the cover (2) form a labyrinth (3) that is interrupted by an insulating element (5).
US08350469B2 Light emitting device having organic compound
When a light emitting element is actuated to allow the light emission, the generation of Joule heat occurs, leading to the decomposition or crystallization of an organic compound to cause the degradation of the light emitting device. Therefore, a light emitting element of the present invention is provided for effecting removing or decreasing the generation of heat. In the present invention, between two electrodes, layers having organic compounds and carbon-based thin films are alternatively laminated one after another for stepping down the driving voltage in the light emitting element using the tunnel effect. In addition, a carbon-based thin film is placed on a film containing an organic compound, so that it prevents the electric field from being locally concentrated and also prevents the generation of short-circuit between the anode and the cathode.
US08350468B2 Organic electroluminescence display including a spacer and method for fabricating the same
Embodiments of the present disclosure provide an organic electroluminescence display device. The display device may include a set of multi-directional spacers that are interposed between the pixels of the display. In one embodiment, the spacers are positioned in both lengthwise and crosswise directions. In another embodiment, the spacers include a first portion that is extends lengthwise between pixels and one or more portions that extend laterally from the first portion between pixels. In yet another embodiment, the spacers include portions that extend in multiple directions between pixels. The spacers may substantially surround each of the pixels and may serve as a boundary, for example, that prevents organic material for one pixel from being incorrectly deposited in another pixel. The spacers can be configured as a support structure, such as, for a metal mask during fabrication of the display device. In addition, the multi-directional aspect of the spacers may be useful in protecting the pixels from damage, such as, when a metal mask is moved during mounting or during fabrication of the display device.
US08350467B2 Flat panel display device and method thereof
A flat panel display device including a display area where an image is displayed and a non-display area located at an outside of the display area includes bank portions arranged in a pattern in the display area and partitioning a plurality of openings, emission elements located in the openings, dummy bank portions formed in the non-display area and integrated therewith, and a sealing passivation layer having a multi-layered structure of organic films and inorganic films alternately arranged, one organic film being located at an interface directly contacting the emission element and one inorganic film located firstly on an outermost portion of the dummy bank portions when the sealing passivation layer extends from the display area to the non-display area.
US08350465B2 Doped garnet fluorescent substance having red shift for pc LEDs
The invention relates to phosphors having a garnet structure of the formula I (Ya,Lub,Sec,Tbd,The,Irf,Sbg)3−x (Al5−yMgy/2Siy/2)O12:Cex (I), where a+b+c+d+e+f+g+h+i=1 x=0.005 to 0.1 and y=0 to 4.0, and to a process for the preparation of these phosphors and to the use as conversion phosphors for conversion of the blue or near-UV emission from an LED.
US08350463B2 Alpha-sialon phosphor
A phosphor of the alpha-sialon type is provided, wherein the general empirical formula is M1p/2Si12−p−qAlp+qOqN16−q:D; where M1 is one or more elements from the group Li, Mg, Ca, Y and the lanthanoids with the exception of Ce and La; D is a co-doping consisting of M2 and Mn, where M2=one or more elements from the group Ce, Pr, Eu, Tb, Yb and Er; in this situation q=0 to 2.5 and p=0.5 to 4 is chosen.
US08350454B2 Iridium alloy for spark plug electrodes
A spark plug comprises a shell having a substantially cylindrical threaded portion for threadable engagement in a cylinder head of an internal combustion engine, an insulator disposed coaxially in the shell, a center electrode disposed coaxially in the insulator, a side ground electrode having a first end coupled to the shell and a second end facing an end of the center electrode to define a spark discharge gap therebetween, and an electrode tip portion secured to either the side ground electrode or the center electrode proximate the spark discharge gap. The tip portion is formed from an alloy comprising from about 60 to about 70 percent by weight iridium, from about 30 to about 35 percent by weight rhodium, from 0 to about 10 percent by weight nickel, from about 3500 to about 4500 parts per million tantalum, and from about 100 to about 200 parts per million zirconium.
US08350453B2 Lamp cover including a phosphor mixed structure for light emitting device
A lamp cover containing phosphor for providing white light emission is disclosed. The lamp cover is comprised of a light-partial-reflective cap structure providing the outer surface of the lamp cover, wherein the light-partial-reflective cap structure is composed of a plurality of light transparent layers and a plurality of vacuum layers that are stacked in an alternating manner from outside to inside, a supporting transparent cap structure providing the inner surface of the lamp cover, and a phosphor mixed structure mechanically supported by the outer surface of the supporting transparent cap structure, wherein the outer surface of the phosphor mixed structure is adjacent to the most inner vacuum layer of the light-partial-reflective cap structure. Once the lamp cover is combined with a phosphor exciting light source, the light-partial-reflective cap structure partially prevents phosphor exciting light from escaping from the lamp cover by using Fresnel reflection.
US08350452B1 HID light bulb and base system
A light bulb is disclosed comprising a base that has an enclosure and a socket connector and a base connector. The enclosure includes conductors for conveying electric power from the socket connector to the base connector. A selectively detachable bulb assembly is further included and has a bulb connector that is mechanically and electrically cooperative with the base connector to secure the bulb assembly to the base and conduct electrical power therethrough. The bulb assembly further includes an inner bulb having a transparent quartz inner layer with a transparent silicon outer layer, and a high intensity discharge (HID) lamp electrically connected to the bulb connector. An outer bulb contains the inner bulb and likewise comprises a transparent quartz inner layer with a transparent silicon outer layer. An instant-on bulb illuminates immediately until the HID lamp reaches its full luminosity.
US08350443B2 Method for producing electric power and device for carrying out said method
The invention encompasses a method for production of electric power from a system of contacts of nanostructured conductive surfaces with a thin water-containing layer, and a hydroelectric generator for carrying out the method. The basis of the invention is a discovery, confirmed by experiments, that the contacts of the conductive surfaces, having nano-dimensional structural and/or parametrical heterogeneities, with the water-containing layer, having a thickness from several nanometers to a fraction of a millimeter, under certain conditions, described in the present disclosure, generate electromotive force in an external electrical load. The invention utilizes new principles for building power systems, which can find further wide application in various areas of science and technology.
US08350439B2 Brushless DC motor of outer rotor type and electronic device using the same
This motor includes a stator whereupon a plurality of magnetic poles are arranged at first prescribed intervals on the outer circumference section, and a rotor which is rotatively arranged on the outer circumference of the stator by having a prescribed space in between and has permanent magnets magnetized to different polarities at second prescribed intervals. The magnetic pole of the stator forms an extending section which extends from a magnetic pole base section in a direction parallel to the permanent magnet, and the extending length of the extending section in the direction parallel to the permanent magnet is same as that of the magnetic pole base section in the direction parallel to the permanent magnet or shorter.
US08350435B2 Interior magnet machine with reduced cogging
An interior permanent magnet machine has non-contiguous, non-magnetic radial slots between the magnets and the cylindrical periphery and the magnets have non-magnetic radial end slots.
US08350434B2 Permanent magnet type rotary electric machine
For providing a permanent magnet type rotary electric machine that can reduce magnetic fluxes concentrated to one side in rotating direction on a magnetic pole circumferential face that causes torque ripple as well as ensure the mechanical strength, in the present invention, an outer circumference of respective magnetic poles is formed in a circular arc having a same curvature as well as the magnetic pole center axes of the respective magnetic poles are displaced with respect to the rotation center of a rotor so that an air gap between a stator and the respective magnetic pole outer circumferences at one side in the rotating direction is widened in comparison with the air gap at the other side.
US08350433B2 Electric motor
It comprises stator including stator core having yoke and a plurality of teeth protruded from yoke, which is formed with slots between adjacent teeth, and rotor having rotor core and permanent magnet formed with a plurality of magnetic poles, which confronts tip ends of teeth via gaps, wherein rotor core is formed by rotor core materials circumferentially equally divided into the predetermined number of divisions, and the least common multiple being N for the number of slots and the number of magnetic poles and the least common multiple being M for the number of slots and the number of divisions, then N is equal to M.
US08350430B2 Rotating machine with sintered magnet and method for producing sintered magnet
An R—Fe—B sintered magnet has a structure including main phase crystal grains and a grain boundary area surrounding the crystal grains. The sintered magnet includes fluorine and a specified metal element selected from elements belonging to Group 2 through Group 16 of periodic table excepting the rare earth element, carbon and boron. The fluorine has a higher concentration in a region closer to a magnet surface than in the center. The specified element also has a higher concentration in the region closer to the surface. The sintered magnet includes oxyfluoride containing carbon, Dy and the metal element in a grain boundary area region at a distance of 1 μm or greater from the magnet surface, and the carbon has a higher concentration than the concentration of the metal element in a region at a distance of 1 μm to 500 μm from the magnet surface.
US08350429B2 Spring assisted magnetic motor
A permanent magnet motor having three chambers aligned end to end where each chamber has a bar magnet. The north pole of the bar magnet in the center chamber faces the north pole of the bar magnet in the chamber to its right and the south pole of the bar magnet in the center chamber faces the south pole of the bar magnet in the chamber to its left. Structure is provided to move the end magnets away from the center magnet and, by means of springs, alternately sequentially snap the end magnets toward the center magnet to drive the center magnet back and forth in its chamber. Shaft members which are connected to gears are provided to control the movement of the end magnets and to convert the back and forth motion of the center magnet to a rotary motion.
US08350425B2 Holder for a position sensor
A holder for a position sensor of an electric machine. The holder includes a pocket for holding the position sensor, an abutment, and a biasing mechanism mountable to a fixture of the electric machine so as to bias the abutment relative to the fixture. Additionally, an electric machine that incorporates the holder, the electric machine including a stator against which the biasing mechanism biases the abutment.
US08350424B2 Dynamoelectric machine
The invention relates to a dynamoelectric machine (1) comprising a stator (2) and a rotor (3). At least the stator (2) has a winding system (4) which is arranged in grooves of the stator (2). Heat is transferred in a substantially radial direction on the front sides (6) of the stator (2) by means of heat pipes (5).
US08350423B2 Cooling system for a motor and associated electronics
A cooling system is provided for an electric motor having control circuitry and including a motor housing surrounding the motor. The motor drives at least one radial fan at one end thereof for directing airflow through the motor housing across the motor. A fan housing encloses the cooling fan and defines a diverter chamber radially outboard of the fan that is sized to divert a portion of the airflow away from the electric motor. A control box contains the control circuitry and includes a base having a heat sink for contacting the control circuitry. The base defines a plenum in communication with the diverter chamber and a channel in communication with the plenum and the heat sink to direct the diverted airflow across the heat sink.
US08350420B2 Winding method of electric motor, electric motor and seatbelt device provided therewith
An electric motor 1 includes a rotor core 22 having n pieces of teeth T arranged in the circumferential direction around which a coil wire 23 is wound, a commutator 24 having n pieces of segments 24a 24b, and 24c, and the coil wire 23 having a connecting wire portion 23a that connects the teeth T and the segments 24a, 24b, and 24c and a crossover portion 23b that interconnects the segments 24a, 24b, and 24c at the opposite pole positions of the commutator 24 around a shaft 23. The crossover portion 23b that connects the i-th (i=1 to n) and the (i+n/2)th of the segments 24a, 24b, and 24c is wound prior to the connecting wire portion 23b that connects the teeth T connected with the i-th segment 24a, 24b, 24c and the (i+1)th segment 24a, 24b, 24c, respectively.
US08350416B2 Transition-rate control for phase-controlled AC power delivery system
A phase-controlled power delivery system for a load such as an incandescent lamp controls the rate of transition of an AC power waveform as a function of switch temperature or other heat-related parameter to provide for time-varying optimization of a tradeoff between heat and noise.
US08350415B2 Switch circuit with inductive load and capacitor
The present invention is a switch circuit equipped with a first switch connected between another end of an inductive load having a one end connected to a one end of a DC power supply and another end of the DC power supply, a capacitor connected between the another end of the inductive load and the another end of the DC power supply and connected in parallel with the first switch, a second switch that connects the another end of the inductive load and the capacitor, a third switch that connects a one end of the capacitor on an inductive load side to the one end of the inductive load so as to be parallel to the second switch, and a control circuit that turns ON the second switch before the first switch is turned OFF and turns OFF the second switch before the first switch is turned ON after being turned OFF.
US08350413B1 Power pack
The power pack includes a plurality of parallel groups. Each parallel group includes a plurality of electrical power sources connected in parallel. The pack also includes a plurality of series groups. Each series group connects in series one of the power sources from each of the parallel groups. The pack also includes a series balancing circuit configured to balance the voltage of the power sources in one of the series groups such that one or more power sources in the series group recharges one or more other power sources in the same series group.
US08350406B2 Electrical system with circuit limiter
An electrical power distribution system automatically limits the number of substantially similar or identical power cable assemblies that are electrically energizable from a power source. A control unit is connected between the power source and the power cable assemblies, and limits the number of power cable assemblies that can be energized in the system by sensing the voltage in a sensing circuit. An applied voltage in the sensing circuit changes in a predictable manner corresponding to the number of power cable assemblies that are electrically connected in the circuit. Each power cable assembly includes an impedance element that is added to the sensing circuit when the corresponding power cable assembly is coupled to the system, and once the detected voltage is beyond a predetermined threshold value, the control unit will ensure that the power cable assemblies are not energized by the power source.
US08350403B2 Tether handling for airborne electricity generators
A power generation system (20) including an airborne electricity generator (30), a tether assembly (40) configured to carry electricity from the generator to land, the tether assembly having a first end portion (42) coupled to the generator, and a winch assembly (50) configured to reel the tether assembly onto a drum (52), wherein the winch assembly is configured to apply a reel tension to the tether assembly reeled onto the drum that is lower than a tension in the first end portion of the tether assembly.
US08350399B2 Microturbine system, and method
A microturbine system provided with a first and a second blade wheel, at least one nozzle for spouting a pressure medium onto the first blade wheel for driving this wheel, wherein the first blade wheel is configured for transferring pressure medium received from the nozzle to the second blade wheel for driving the second blade wheel, the arrangement being such that the first and second blade wheel are rotatable in opposite directions under the influence of the pressure medium, and a first and second electricity generator, respectively, coupled to the first and second blade wheel, respectively. Also included is the method for generating electricity using the microturbine system.
US08350397B2 Current source converter-based wind energy system
Switching control systems and methods are presented for controlling power conversion systems to provide electrical power to a grid or other load in which a synchronous machine is driven by a wind turbine or other prime mover to provide generator power to a switching type current source converter (CSC), with a current source rectifier (CSR) of the CSC being switched to provide d-axis control of the synchronous machine current based on grid power factor feedback, and with a current source inverter (CSI) of the CSC being switched to provide leading firing angle control and selective employment of dumping resists to dissipate excess generator energy in a fault mode when a grid voltage drops below a predetermined level.
US08350395B2 Maritime device for producing electric power
An energy accumulator and rectifier equipment for converting and generating renewable energy from ocean waves and winds, which includes a storage tank or compressed air accumulator, a series of vertical tubes filled with non-compressible fluid so that it can displace movable elements, forming a group, wherein each group is in connection with another similar group at both the upper level and the lower level by means of a fluid circulation pipes and by means of a pipe of smaller diameter, at the upper and lower portion, for air circulation, and wherein the fluid circulation pipes of every group are attached to a common pipe at the upper level which conveys the fluid toward a turbine-generator to produce electricity and a common pipe at the lower level to recirculate fluid toward the cylinders.
US08350389B2 Semiconductor device and information processing system including the same
A semiconductor device includes a plurality of core chips and an interface chip that controls the core chips. Each of the core chips and the interface chip includes plural through silicon vias that penetrate a semiconductor substrate and plural pads respectively connected to the through silicon vias. The through silicon vias include a through silicon via of a power source system to which a power source potential or a ground potential is supplied, and a through silicon via of a signal system to which various signals are supplied. Among the pads, at least an size of a pad connected to the through silicon via of the power source system is larger than a size of a pad connected to the through silicon via of the signal system. Therefore, a larger parasitic capacitance can be secured.
US08350388B2 Component built-in wiring board and manufacturing method of component built-in wiring board
Disclosed is a component built-in wiring board, including a first insulating layer; a second insulating layer positioned in a laminated state on the first insulating layer; a semiconductor element buried in the second insulating layer, having a semiconductor chip with terminal pads and having surface mounting terminals arrayed in a grid shape connected electrically with the terminal pads; an electric/electronic component further buried in the second insulating layer; a wiring pattern sandwiched between the first insulating layer and the second insulating layer, including a first mounting land for the semiconductor element and a second mounting land for the electric/electronic component; a first connecting member connecting electrically the surface mounting terminal of the semiconductor element with the first mounting land; and a second connecting member connecting electrically the terminals of the electric/electronic component with the second mounting land, made of a same material as a material of the first connecting member.
US08350381B2 Device and method for manufacturing a device
A device includes a first semiconductor chip and a first encapsulant that encapsulates the first semiconductor chip and that includes a cavity. A carrier and an electrical component are mounted on the carrier. The carrier is arranged such that the electrical component is enclosed by the cavity.
US08350379B2 Package with power and ground through via
A wire bond design integrated circuit with a substrate having a front side and an opposing back side. Circuitry is disposed on the font side. Electrically conductive vias are disposed through the substrate from the front side to the back side, and are electrically connected to the circuitry such that the electrically conductive vias provide power and ground services only for the circuitry. Bonding pads are disposed on the front side, and are electrically connected to the circuitry such that the bonding pads provide signal communication only for the circuitry.
US08350378B2 Press-fit power diode
A diode, e.g., a press-fit power diode for a rectifier in a motor vehicle, includes a semiconductor chip which is connected to a head wire and a base via solder layers. A plastic sheathing, which is situated at least in the chip area and includes a plastic sleeve, enables a hard casting compound to be used and establishes a mechanical connection between the base and the head wire and forms a housing together with the base. An undercut, which extends into the casting compound, and a gap between the sleeve and the edge of the base achieve a compact design. Bevels provided on both sides enable the diode to be pressed into the rectifier from two sides.
US08350376B2 Bondwireless power module with three-dimensional current routing
According to an exemplary embodiment, a bondwireless power module includes a common output pad coupling an emitter/anode node of a high side device to a collector/cathode node of a low side device. The bondwireless power module also includes a high side conductive clip connecting a collector of the high side device to a cathode of the high side device, and causing current to traverse through the high side conductive clip to another high side conductive clip in another power module. The bondwireless power module further includes a low side conductive clip connecting an emitter of the low side device to an anode of the low side device, and causing current to traverse through the low side conductive clip to another low side conductive clip in the another power module. The bondwireless power module can be a motor drive inverter module.
US08350370B2 Wide angle oval light emitting diode package
The present invention is directed to LED packages and LED displays utilizing LED packages where the peak emission of the LED displays can exhibit improved emission characteristics. In some embodiments the improved characteristics include a wider horizontal emission angle for the LED packages according to the present invention, which results in improved emission characteristics for the LED display such as a wider far field pattern. This provides improved picture intensity and quality when viewing the display at different horizontal viewing angles. Different embodiments also provide for improved emission characteristics for LED packages emitting different colors of light when viewing at different vertical angles. In one embodiment the red and green LED packages can have emission patterns that are substantially the same at different vertical viewing angles within a range. This helps the colors of the display appear consistent at those angles.
US08350369B2 High power semiconductor package
Provided is a high power semiconductor package including: an insulation substrate having first and second surfaces opposite to each other; an interconnection patterns formed on the first surface of the insulation substrate, the interconnection patterns including a plurality of first dimples; a power control semiconductor chip mounted on the first surface of the insulation substrate, the power control semiconductor chip electrically connected with the interconnection patterns; and an encapsulation member encapsulating the insulation substrate, the interconnection patterns, and the power control semiconductor chip and exposing at least a portion of the second surface of the insulation substrate.
US08350367B2 Semiconductor device packages with electromagnetic interference shielding
Described herein are semiconductor device packages with EMI shielding and related methods. In one embodiment, a semiconductor device package includes: (1) a substrate unit including a grounding element disposed adjacent to a periphery of the substrate unit; (2) a semiconductor device disposed adjacent to an upper surface of the substrate unit; (3) a package body disposed adjacent to the upper surface and covering the semiconductor device; and (4) an EMI shield disposed adjacent to exterior surfaces of the package body and electrically connected to a connection surface of the grounding element. A lateral surface of the package body is substantially aligned with a lateral surface of the substrate unit, and the connection surface of the grounding element is electrically exposed adjacent to the lateral surface of the substrate unit. The grounding element corresponds to a remnant of a grounding via, and provides an electrical pathway to ground electromagnetic emissions incident upon the EMI shield.
US08350365B1 Mitigation of well proximity effect in integrated circuits
A hard implantation mask layer is formed on a semiconductor wafer. An etch mask layer is formed on the hard implantation mask layer and patterned. The hard implantation mask layer is etched to form a well implantation pattern and ions are implanted into the semiconductor wafer to form wells in the semiconductor wafer, in areas where the semiconductor wafer is not covered by the well implantation mask.
US08350359B2 Semiconductor device using an aluminum interconnect to form through-silicon vias
An aluminum lateral interconnect of a Back End of the Line (BEOL) is used to define the x and y dimensions of a through-silicon via in a semiconductor chip formed in a silicon substrate. The TSV includes one or more aluminum annulus formed on a surface of the substrate, and a deep trench in the substrate having a diameter that is determined by the diameter of the aluminum annulus. The annulus can also be provided with a conductive strap upon which a capacitor can be formed. The strap can also be used to provide a connection of the TSV to other BEOL interconnects.
US08350358B2 Techniques for placement of active and passive devices within a chip
A semiconductor die includes a semiconductive substrate layer with first and second sides, a metal layer adjacent the second side of the semiconductive substrate layer, one or more active devices in an active layer on the first side of the semiconductive substrate layer; and a passive device in the metal layer in electrical communication with the active layer. The passive device can electrically couple to the active layer with through silicon vias (TSVs).
US08350355B2 Electrostatic discharge devices
Electrostatic discharge devices and methods of forming thereof are disclosed. In one embodiment, a semiconductor device includes an electrostatic discharge (ESD) device region disposed within a semiconductor body. A first ESD device is disposed in a first region of the ESD device region, and a second ESD device disposed in a second region of the ESD device region. The second region is separated from the first region by a first trench.
US08350354B2 Semiconductor device structure with strain layer
A semiconductor device with a strain layer and a method of fabricating the semiconductor device with a strain layer that can reduce a loading effect are provided. By arranging active dummies and gate dummies not to overlap each other, the area of active dummy on which a strain layer dummy will be formed can be secured, thereby reducing the loading effect.
US08350351B2 Semiconductor light receiving device
A semiconductor light receiving device includes: a first semiconductor light receiving element that is provided on a semiconductor substrate and has a mesa structure having an upper electrode to be coupled to an electrode wiring of a mounting carrier and a lower electrode; a first mesa that is provided on the semiconductor substrate and has an upper electrode coupled electrically to a lower electrode of the first semiconductor light receiving element with a wiring provided on the semiconductor substrate; and a second mesa that is provided on the semiconductor substrate and has an upper electrode that has a same electrical potential as the upper electrode of the first semiconductor light receiving element when coupled to the electrode wiring on the mounting carrier.
US08350350B2 Optical sensor
In an infrared sensor (1) having a bolometer element (11) and a reference element (21), the reference element (21) comprises a bolometer film (22), a substrate-side insulating film (31) formed on the substrate-side surface of the bolometer film (22), a heat dissipation film (23) made of amorphous silicon formed on the substrate-side surface of the bolometer film (22) with the substrate-side insulating film (31) interposed therebetween, and a plurality of heat dissipation columns (25) made of amorphous silicon thermally connected to the heat dissipation film (23) and a substrate (10), while the bolometer film (22) and substrate-side insulating film (31) are formed such as to extend over a side face of the heat dissipation film (23) intersecting a surface of the substrate (10). Thus configured infrared sensor (1) can efficiently reduce the influence of temperature changes in the environment in use, while being made smaller.
US08350349B2 Solid-state imaging device, method of manufacturing thereof, and electronic apparatus
Provided is a solid-state imaging device including a first photoelectric-conversion-portion selectively receiving a first wavelength light in incident light and performing photoelectric conversion; and a second photoelectric-conversion-portion selectively receiving a second wavelength light which is shorter than the first wavelength, wherein the first photoelectric-conversion-portion is laminated above the second photoelectric-conversion-portion in an imaging area of a substrate so that the second photoelectric-conversion-portion receives the light transmitting the first photoelectric-conversion-portion, wherein a transmitting portion is formed in the first photoelectric-conversion-portion so that the second wavelength light transmits the second photoelectric-conversion-portion more than other portions, and wherein the transmitting portion is formed to include a portion satisfying the following Equation within a width D defined in the direction of the imaging area, a refraction index n of a peripheral portion of the transmitting portion, and the longest wavelength λc of the second wavelength range selectively photoelectrically-converted in the second photoelectric-conversion-portion: λc/n≦2D.
US08350344B2 Semiconductor device and method of fabricating the same
Provided are a semiconductor device and a method of fabricating the same. The semiconductor device may include a charge storage structure and a gate. The charge storage structure is formed on a substrate. The gate is formed on the charge storage structure. The gate includes a lower portion formed of silicon and an upper portion formed of metal silicide. The upper portion of the gate has a width greater than that of the lower portion of the gate.
US08350341B2 Method and structure for work function engineering in transistors including a high dielectric constant gate insulator and metal gate (HKMG)
Adjustment of a switching threshold of a field effect transistor including a gate structure including a Hi-K gate dielectric and a metal gate is achieved and switching thresholds coordinated between NFETs and PFETs by providing fixed charge materials in a thin interfacial layer adjacent to the conduction channel of the transistor that is provided for adhesion of the Hi-K material, preferably hafnium oxide or HfSiON, depending on design, to semiconductor material rather than diffusing fixed charge material into the Hi-K material after it has been applied. The greater proximity of the fixed charge material to the conduction channel of the transistor increases the effectiveness of fixed charge material to adjust the threshold due to the work function of the metal gate, particularly where the same metal or alloy is used for both NFETs and PFETs in an integrated circuit; preventing the thresholds from being properly coordinated.
US08350340B1 Structure of output stage
A structure of an output stage includes a first electrode, a second electrode, a third electrode, multiple first auxiliary electrodes connected to the first electrode, multiple second auxiliary electrodes and multiple third auxiliary electrodes both connected to the second electrode, multiple fourth auxiliary electrodes connected to the third electrode, multiple first transistors and multiple second transistors. The widths of each the first auxiliary electrode and each the fourth auxiliary electrode are inversely proportional to the distance thereof respectively from the first electrode and the third electrode. The width of each of the second auxiliary electrodes and the third auxiliary electrodes is inversely proportional to the distance thereof from the second electrode. The first and second auxiliary electrodes are electrically connected to each other respectively through the turned-on first transistors. The third and fourth auxiliary electrodes are electrically connected to each other respectively through the turned-on second transistors.
US08350321B2 Semiconductor device having saddle fin transistor and manufacturing method of the same
The present invention discloses a transistor having the saddle fin structure. The saddle fin transistor of the present invention has a structure in which a landing plug contact region, particularly, a landing plug contact region on an isolation layer is elevated such that the landing plug contact SAC (Self Aligned Contact) fail can be prevented.
US08350320B2 Memory array and memory device
A memory array with staggered local data/bit lines extending generally in a first direction formed in an upper surface of a substrate and memory cell access transistors extending generally upward and aligned generally atop a corresponding local data/bit line. Selected columns of the memory cell access transistors are sacrificed to define local data/bit access transistors which are interconnected with overlying low resistance global data/bit lines. The global data/bit lines provide selectable low resistance paths between memory cells and sense amplifiers. The sacrificed memory cell access transistors and staggered local data/bit lines provide increased footprints for sense amplifiers to facilitate increased circuit integration.
US08350319B2 Semiconductor device
A semiconductor device includes a gate pad, a gate wiring conductor connected to the gate pad, and a gate electrode formed under the gate pad and the gate wiring conductor. Portions of the gate electrode closer to the gate pad have a higher resistance per unit area than portions of the gate electrode farther away from the gate pad.
US08350316B2 Phase change memory cells having vertical channel access transistor and memory plane
Memory devices are described along with methods for manufacturing. A memory device as described herein comprises a plurality of word lines overlying a plurality of bit lines, and a plurality of field effect transistors. Field effect transistors in the plurality of field effect transistors comprises a first terminal electrically coupled to a corresponding bit line in the plurality of bit lines, a second terminal overlying the first terminal, and a channel region separating the first and second terminals and adjacent a corresponding word line in the plurality of word lines. The corresponding word line acts as the gate of the field effect transistor. A dielectric separates the corresponding word line from the channel region. A memory plane comprises programmable resistance memory material electrically coupled to respective second terminals of the field effect transistors, and conductive material on the programmable resistance memory material and coupled to a common voltage.
US08350306B2 Capacitor to be incorporated in wiring substrate, method for manufacturing the capacitor, and wiring substrate
A wiring substrate in which a capacitor is provided, the capacitor comprising a capacitor body including a plurality of dielectric layers and internal electrode layers provided between the different dielectric layers, wherein said capacitor body has, in at least one side face of said capacitor body, recesses extending in a thickness direction of said capacitor body from at least one of a first principal face of said capacitor body and a second principal face positioned on the side opposite to the first principal face.
US08350305B2 Solid-state imaging device and camera
A solid-state imaging device is provided. The solid-state imaging device includes: pixels arrayed; a photoelectric conversion element in each of the pixels; a read transistor for reading electric charges photoelectrically-converted in the photoelectric conversion elements to a floating diffusion portion; a shallow trench element isolation region bordering the floating diffusion portion; and an impurity diffusion isolation region for element isolation regions other than the shallow trench element isolation region.
US08350304B2 Junction-field-effect-transistor devices and methods of manufacturing the same
A junction-field-effect-transistor (JFET) device includes a substrate of a first-type impurity, a first well region of a second-type impurity in the substrate, a pair of second well regions of the first-type impurity separated from each other in the first well region, a third well region of the first-type impurity between the pair of second well regions, a first diffused region of the second-type impurity between the third well region and one of the second well regions, and a second diffused region of the second-type impurity between the third well region and the other one of the second well regions.
US08350302B2 Organic light emitting display apparatus
An organic light emitting display apparatus is disclosed. The organic light emitting display apparatus includes: a substrate, a seal facing the substrate, bonded to the substrate, a display area disposed on the substrate configured to produce an image, a pad area disposed on the substrate, present on at least one side of the display area, an insulating layer directly extending from the display area, formed on the pad area, a first adhesive layer surrounding the display area, which bonds the substrate to the seal, and comprising an organic material, and a second adhesive layer insulated from the pad area by the insulating layer, disposed outside the first adhesive layer, which bonds the substrate to the seal.
US08350301B2 Semiconductor photodiode device and manufacturing method thereof
A semiconductor photodiode includes a semiconductor substrate; a first conduction type first semiconductor layer formed above the semiconductor substrate; a high resistance second semiconductor layer formed above the first semiconductor layer; a first conduction type third semiconductor layer formed above the second semiconductor layer; and a second conduction type fourth semiconductor layer buried in the second semiconductor layer, in which the fourth semiconductor layer is separated at a predetermined distance in a direction horizontal to the surface of the semiconductor substrate.
US08350300B2 Semiconductor device having air gaps in multilayer wiring structure
A semiconductor device comprises a semiconductor substrate, and a multilayer wiring structure arranged on the semiconductor substrate, the multilayer wiring structure including a plurality of first electrically conductive lines, an insulating film covering the plurality of first electrically conductive lines, and a second electrically conductive line arranged on the insulating film so as to intersect the plurality of first electrically conductive lines, where the insulating film has gaps in at least some of a plurality of regions where the plurality of first electrically conductive lines and the second electrically conductive line intersect each other, and the width of the gap in a direction along the second electrically conductive line is not larger than the width of the first electrically conductive line.
US08350297B2 Compound semiconductor device and production method thereof
A compound semiconductor device is comprised of: a compound semiconductor layer including a first active layer and a second active layer forming a hetero junction with the first active layer so as to naturally generate a two-dimensional carrier gas channel in the first active layer along the hetero junction; a first electrode formed on the second active layer; a second electrode in ohmic contact with the first active layer and isolated from the first electrode; and a channel modifier for locally changing a part of the first active layer under the channel modifier into a normally-off state, the channel modifier being formed on the second active layer so as to enclose but be isolated from the first electrode and the second electrode.
US08350294B2 Compensated gate MISFET and method for fabricating the same
A MISFET, such as a GaN transistor, with low gate leakage. In one embodiment, the gate leakage is reduced with a compensated GaN layer below the gate contact and above the barrier layer. In another embodiment, the gate leakage is reduced by employing a semi-insulating layer below the gate contact and above the barrier layer.
US08350293B2 Field effect transistor and method of manufacturing the same
A p-type nitride compound semiconductor layer is formed on a buffer formed on a substrate. An n-type contact region is formed by ion implantation under a source electrode and a drain electrode. An electric-field reducing layer made of an n-type nitride compound semiconductor is formed on the p-type nitride compound semiconductor layer. A carrier density of the electric-field reducing layer is lower than that of the n-type contact region. A first end portion of the electric-field reducing layer contacts with the n-type contact region, and a second end portion of the electric-field reducing layer overlaps with a gate electrode.
US08350292B2 Gallium nitride epitaxial crystal, method for production thereof, and field effect transistor
The present invention provides a gallium nitride type epitaxial crystal, a method for producing the crystal, and a field effect transistor using the crystal. The gallium nitride type epitaxial crystal comprises a base substrate and the following (a) to (e), wherein a connection layer comprising a gallium nitride type crystal is arranged in an opening of the non-gallium nitride type insulating layer to electrically connect the first buffer layer and the p-conductive type semiconductor crystal layer. (a) a gate layer, (b) a high purity first buffer layer containing a channel layer contacting an interface on the base substrate side of the gate layer, (c) a second buffer layer arranged on the base substrate side of the first buffer layer, (d) a non-gallium nitride type insulating layer arranged on the base substrate side of the second buffer layer, and having the opening at a part thereof, and (e) a p-conductive type semiconductor crystal layer arranged on the base substrate side of the insulating layer.
US08350288B2 Gallium nitride devices with electrically conductive regions
Semiconductor structures comprising a III-nitride (e.g., gallium nitride) material region and methods associated with such structures are provided. In some embodiments, the structures include an electrically conductive material (e.g., gold) separated from certain other region(s) of the structure (e.g., a silicon substrate) by a barrier material in order to limit, or prevent, undesirable reactions between the electrically conductive material and the other component(s) which can impair device performance. In certain embodiments, the electrically conductive material may be formed in a via. For example, the via can extend from a topside of the device to a backside so that the electrically conductive material connects a topside contact to a backside contact. The structures described herein may form the basis of a number of semiconductor devices including transistors (e.g., PET), Schottky diodes, light-emitting diodes and laser diodes, amongst others.
US08350287B2 Light emitting element
A heat radiation structure of a light emitting element has leads, each lead having a plurality of leg sections, and a light emitting chip mounted on any one of the leads. The present invention can provide a high-efficiency light emitting element, in which a thermal load is reduced by widening a connecting section through which a lead and a chip seating section of the light emitting element are connected, and the heat generated from a heat source can be more rapidly radiated to the outside. Further, the present invention can also provide a high-efficiency light emitting element, in which heat radiation fins are formed between a stopper and a molding portion of a lead of the light emitting element so that natural convection can occur between the heat radiation fins, and an area in which heat radiation can occur is widened to maximize a heat radiation effect.
US08350285B2 Semiconductor light-emitting device and method for manufacturing same
A semiconductor light-emitting device of the invention includes: a semiconductor layer including a light-emitting layer and having a first major surface and a second major surface opposite to the first major surface; a phosphor layer facing to the first major surface; an interconnect layer provided on the second major surface side and including a conductor and an insulator; and a light-blocking member provided on a side surface of the semiconductor layer and being opaque to light emitted from the light-emitting layer.
US08350283B2 Semiconductor light emitting device and method for manufacturing same
According to one embodiment, a semiconductor light emitting device includes a light emitting unit, first and second conductive members, an insulating layer, a sealing member, and an optical layer. The light emitting unit includes a semiconductor stacked body and first and second electrodes. The semiconductor stacked body includes first and second semiconductor layers and a light emitting layer, and has a major surface on a second semiconductor layer side. The first and second electrodes are connected to the first and second semiconductor layers on the major surface side, respectively. The first conductive member is connected to the first electrode and includes a first columnar portion covering a portion of the second semiconductor. The insulating layer is provided between the first columnar portion and the portion of the second semiconductor. The sealing member covers side surfaces of the conductive members. The optical layer is provided on the other major surface.
US08350281B2 Display device, display apparatus and method of adjusting a color shift of white light in same
A display device includes: an optical cavity portion; and a light emitting layer, wherein a peak wavelength of an internal emission spectrum of the light emitting layer is identical to a peak wavelength of a multiple interference filter spectrum of the optical cavity portion, and wherein a color shift Δ uv of white light in the display device at a viewing angle of 60° is less than or equal to 0.015. A method of adjusting a color shift of white light in a display device includes: setting a peak wavelength of a multiple interference filter spectrum obtained by an optical cavity portion in the display device equal to a peak wavelength of an internal emission spectrum of a light emitting layer in the display device; and adjusting a position of the light emitting layer in a thickness direction thereof.
US08350274B2 Light emitting device, method of manufacturing the light emitting device, light emitting device package, and lighting unit
Provided are a light emitting device, a method for fabricating the light emitting device, a light emitting device package, and a lighting unit. The light emitting device includes a conductive support substrate, a first reflective layer on the conductive support substrate, a second reflective layer in which at least portion thereof is disposed on a side surface of the first reflective layer, a light emitting structure including a first conductive type semiconductor layer, a second conductive type semiconductor layer, and an active layer between the first conductive type semiconductor layer and the second conductive type semiconductor layer on the first and second reflective layers, and an electrode on the light emitting structure. The second reflective layer schottky-contacts the light emitting structure.
US08350272B2 Semiconductor device
A semiconductor device which is designed based on RDR, suppresses the occurrence of a trouble at the boundary between an active region and a power wire and therearound and is small in size and highly integrated. The semiconductor device includes a first conductive impurity region for functional elements which is formed over the main surface of a semiconductor substrate and a second conductive impurity region for power potential to which power potential is applied in at least one standard cell. It also includes insulating layers which are formed over the main surface of the semiconductor substrate and have throughholes reaching the main surface of the semiconductor substrate, and a conductive layer for contact formed in the throughholes of the insulating layers. The impurity region for functional elements and the impurity region for power potential are electrically coupled to each other through the conductive layer for contact which is formed astride the impurity region for functional elements and the impurity region for power potential.
US08350271B2 Transistor including shallow trench and electrically conductive substrate for improved RF grounding
Disclosed is an RF power FET or HEMT including an electrically-conductive substrate, a grounding metallization layer disposed on a bottom surface of the electrically-conductive substrate, an active area comprising at least one cell including source, gate and drain electrodes disposed over a top surface of the electrically-conductive substrate, and an electrically-conductive shallow trench electrically connecting the source electrode to the grounding metallization layer by way of the electrically-conductive substrate. This configuration results in the effective RF ground being very close to the active area of the FET in order to reduce parasitic source inductance and resistance. This results in potentially higher gain, higher saturation point, higher 3rd-order intercept, more efficient combining of the input RF signal, and more efficient extraction of the output RF signal. Additional benefits include reduced process complexity, such as, reduced need for plated air bridges, via holes formation and plating, front and back lithography alignment.
US08350270B2 Silicon carbide semiconductor device and method for manufacturing the same
A silicon carbide MOSFET that exhibits a high source-to-drain withstand voltage and that involves a smaller difference between gate-to-drain capacitance achieved in an activated state and gate-to-drain capacitance achieved in a deactivated state. A silicon carbide drift layer of a first conductivity type is provided on a silicon carbide substrate of a first conductivity type; a pair of base regions are provided in a surface layer portion of the silicon carbide drift layer and exhibit a second conductivity type; a pair of source regions are provided in interiors of surface layer portions of the pair of base regions and exhibit a first conductivity type; and semi-insulating regions are provided between the silicon carbide substrate and the pair of base regions.
US08350268B2 Thin film transistor substrate
A thin film transistor substrate including a thin film transistor having a drain electrode with an electrode portion, which overlaps with a semiconductor layer, and an extended portion, which extends from the electrode portion and has a portion overlapping with a storage electrode or storage electrode line. A passivation layer is arranged on the drain electrode, and it has a contact hole that partially exposes the extended portion of the drain electrode without exposing a step in the extended portion caused by the storage electrode or storage electrode line. A pixel electrode is arranged on the passivation layer and is electrically connected with the extended portion of the drain electrode through the contact hole.
US08350262B2 Nonvolatile memory device and nonvolatile memory array including the same
A nonvolatile memory device having self-presence diode characteristics, and/or a nonvolatile memory array including the nonvolatile memory device may be provided. The nonvolatile memory device may include a lower electrode, a first semiconductor oxide layer on the lower electrode, a second semiconductor oxide layer on the first semiconductor oxide layer, and/or an upper electrode on the second semiconductor oxide layer.
US08350259B2 Electronic circuit
An electronic circuit includes at least two organic components interconnected by conductor tracks and having a common carrier substrate. The components and the conductor tracks are formed from layer portions. An uppermost layer portion, remote from the carrier substrate, of the electronic circuit is of a patterned configuration comprising an electrically conducting material. The patterned uppermost layer portion on its side remote from the carrier substrate is provided with at least one protective layer arranged in congruent relationship with the uppermost layer portion. The at least two organic components include at least one first component of a first component type and at least one second component of a second component type different therefrom. Components of the same component type are respectively protected by a protective layer of the same composition and/or the same structure corresponding to that component type and differing from one another according to the corresponding component type.
US08350252B2 Boundary-modulated nanoparticle junctions and a method for manufacture thereof
A method of providing miniaturized size down to nanoscale electronic materials, which may be easily incorporated into the future ever-scaling down power electronics, microelectronics and nanoelectronics device systems, is disclosed. A linear or nonlinear nanoparticle (nanowire) junction design that allows precise controllability over an electronic device (e.g., a varistor) performance, which is typically difficult for the traditional sintered bulk varistor, is also disclosed. A localized doping and chemical modulation, across junctions allows flexible and tunable design over the nanoscale grain boundary band engineering is further disclosed. Furthermore, a method of operating memory, using electrostatic potential modulated coding and decoding across periodic nanoparticle grain boundary linearly, is also disclosed.
US08350250B2 Nitride-based light emitting device
A nitride-based light emitting device capable of achieving an enhancement in light emission efficiency and an enhancement in reliability is disclosed. The nitride-based light emitting device includes a first-conductivity semiconductor layer, a second-conductivity semiconductor layer, an active layer arranged between the first-conductivity semiconductor layer and the second-conductivity semiconductor layer, the active layer including at least one pair of a quantum well layer and a quantum barrier layer, a plurality of first layers arranged on at least one of an interface between the first-conductivity semiconductor layer and the active layer and an interface between the second-conductivity semiconductor layer and the active layer, the first layers having different energy band gaps or different thicknesses, and second layers each interposed between adjacent ones of the first layers, the second layers exhibiting an energy band gap higher than the energy band gaps of the first layers.
US08350249B1 Coalesced nanowire structures with interstitial voids and method for manufacturing the same
A semiconductor device, such as an LED, includes a plurality of first conductivity type semiconductor nanowire cores located over a support, a continuous second conductivity type semiconductor layer extending over and around the cores, a plurality of interstitial voids located in the second conductivity type semiconductor layer and extending between the cores, and first electrode layer that contacts the second conductivity type semiconductor layer and extends into the interstitial voids.
US08350245B2 Variable resistance element and nonvolatile semiconductor memory device using the same
To provide a variable resistance element capable of preventing the interface resistance, in a side of the variable resistance element in which resistance change is not allowed, from changing to high resistance due to applied voltage. The variable resistance element is configured by providing a variable resistance film (265) between a first electrode (280) and a second electrode (250), the oxygen concentration within the film of the variable resistance film (265) is high at the side of an interface with the second electrode (250) (high-concentration variable resistance layer (260)) and low at the side of an interface with the first electrode (280) (low-concentration variable resistance layer (270)), and the junction surface area between the low-concentration variable resistance layer (270) and the first electrode (280) is larger than the interface surface area between the high-concentration variable resistance layer (260) and the second electrode (250).
US08350240B2 Device and method for generating and detecting coherent electromagnetic radiation in the THz frequency range
The present invention concerns a device for generating and detecting coherent electromagnetic radiation (8) in the THz frequency range, comprising an optically parametric oscillator (2) for generating electromagnetic radiation in the THz frequency range (8). To provide a device for generating and detecting electromagnetic radiation in the THz frequency range it is proposed in accordance with the invention that it has a coherent phase-sensitive detector (3, 21) for detecting intensity and phase of the electromagnetic radiation (8) generated by the optically parametric oscillator (2).
US08350239B2 Pen specific for erasable media usage
Exemplary embodiments provide materials and methods for a pen that can include a writing end for writing an image on an erasable medium and an erasing end for locally erasing an image from the erasable medium.
US08350238B2 Device patterning using irradiation
In one embodiment, a method for creating a pattern in a layer of an organic electronic device that includes selectively irradiating a portion of the layer is provided, and devices and sub-assemblies made by the same.
US08350229B2 Fluorescence observation apparatus
A quantitative fluorescence image and appropriate brightness is acquired and observed. Provided is a fluorescence observation apparatus including: an illumination section that includes a light source for irradiating an observation target region with illumination light and excitation light; a fluorescence image acquisition section that acquires a fluorescence image from fluorescence produced in the observation target region; a white-light image acquisition section that acquires a reference image from return light returning from the observation target region; an exposure-time adjustment unit that adjusts the exposure time based on the luminance value of the reference image; a diaphragm control section and a semiconductor laser control section that control the intensity of the illumination light and that of the excitation light based on the exposure time; a first normalization section that normalizes the luminance of the reference image and the fluorescence image by the exposure time; a second normalization section that normalizes the luminance of the reference image and the fluorescence image by the light intensity; and an image correction section that corrects the fluorescence image by the reference image, by using at least one of the normalized reference image or fluorescence image.
US08350228B2 Germicidal fixture and methods
The present disclosure relates to adapting a commonly used lighting fixture that is generally specified as the primary lighting source for illuminating a particular area as the apparatus for enclosing an additional UV lighting mechanism. Further, the disclosure relates to a device that can be integrated into a light fixture used with a suspended grid ceiling or a solid ceiling. Also, the present disclosure relates to a germicidal fixture used in association with a light fixture, and to an apparatus for a new germicidal light fixture and for replacing or converting an existing light fixture for efficient germicidal use.
US08350225B1 Solid state tissue equivalent detector, main component for a light-weight tissue equivalent microdosimeter
An organic semiconductor device for detecting and measuring radiation has a total active area of less than 100 square microns (□m2) and comprises at least two bulk organic semiconductor regions with each region connected on one side to an independent biasing voltage electrode and connected on an opposing side to a common output electrode.
US08350221B2 Apparatus and method for generating countable pulses from impinging X-ray photons; and corresponding imaging device
The present invention relates to an apparatus (10) for generating countable pulses (30) from impinging X-ray (12, 14) in an imaging device (16), in particular in a computer tomograph, the apparatus (10) comprising a pre-amplifying element (18) adapted to convert a charge pulse (20) generated by an impinging photon (12, 14) into an electrical signal (22) and a shaping element (26) having a feedback loop (28) and adapted to convert the electrical signal (22) into an electrical pulse (30), wherein a delay circuit (38) is connected to the feedback loop (28) such that a time during which the feedback loop (28) collects charges of the electrical signal (22) is extended in order to improve an amplitude of the electrical pulse (30) at an output (56) of the shaping element (26). The invention also relates to a corresponding imaging device (16) and a corresponding method.
US08350220B2 Enhanced PET scanner detector module
A programmable memory is provided in each of a plurality of detector modules arrayed in a positron emission tomography (PET) scanner. Each detector module memory stores data associated with its respective detector module. Each memory may be coupled to a processor via a transmission bus. A display device may be coupled to the processor for displaying information relating to information obtained from the detector module memories.
US08350217B2 Pixel, pixel array, and image sensor including the pixel array
Disclosed are a pixel, a pixel array, and an image sensor including the pixel array. The pixel includes a first photo-sensing unit to detect a visible light and an IR, and a second photo-sensing unit provided at one side of the first photo-sensing unit to detect a light in which the IR is blocked.
US08350214B2 Charged particle beam applied apparatus
Provided is a multi-beam type charged particle beam applied apparatus in an implementable configuration, capable of achieving both high detection accuracy of secondary charged particles and high speed of processing characteristically different specimens. An aperture array (111) includes plural aperture patterns. A deflector (109) for selecting an aperture pattern through which a primary beam passes is disposed at the position of a charged particle source image created between an electron gun (102), i.e., a charged particle source, and the aperture array (111). At the time of charge-control beam illumination and at the time of signal-detection beam illumination, an aperture pattern of the aperture array (111) is selected, and conditions of a lens array (112), surface electric-field control electrode (118) and the like are switched in synchronization with each beam scanning. Thus, the charges are controlled and the signals are detected at different timings under suitable conditions, respectively.
US08350211B2 Quantum entity state processing system and method having heterogeneously influenceable quantum entity secondary states and conditioned quantum entity tertiary states
Systems and methods are described for processing quantum entity states by utilizing interference phenomena, and more specifically self-interference outcomes. The quantum entity states are embodiable in fermions and/or bosons, expressly including photons. Certain embodiments can utilize input quantum entity states that encompass one or more separable quantum entities and can be arranged to produce predictable outcome differences that are alterable in accordance with differences and/or similarities between separate input quantum entities. Additional outcome alterations are effectible via static and/or dynamic quantum entity state influencing constituents. Even further outcome alterations are effectible by associative quantum state influencing constituents that are additionally utilizable for interrelating separable embodiments. Interrelations of separable embodiments are achievable as well by employing at least a portion of at least a first outcome quantum entity state as an intermediary or a final interactor with at least a portion of a differing separable embodiments' quantum entity state.
US08350210B1 Embedded optical interconnect devices and methods of use thereof
In one instance, an optical interconnection is embedded in a structure. The optical interconnection embedded in the structure enables interfacing electrical subsystems and sharing electrical signals across the structure by converting electrical signals into optical and vice a versa by means of the optical data pipe technology. The system of these teachings enables methods for decreasing the weight and size of the system, for decreasing sensitivity to electromagnetic interference and for obtaining data from the interior of a system.
US08350208B1 Two-terminal multi-color photodetectors and focal plane arrays
Two-terminal multi junction photodetectors and focal plane arrays for multi-color detection or imaging acquisition can be formed by connecting photodiodes with different bandgaps or wavelengths, through tunnel diodes, in series with the same polarization. Under reverse bias in the dark, the total current going through such multi junction photodetectors is dictated by the smallest reverse saturation current of the photodiodes. When in operating mode, a set of light sources with different wavelengths corresponding to each individual photodiode can be used to optically bias all the photodiodes except the detecting photodiode Under illumination, all other photodiodes work in the photovoltaic mode and have much higher maximum possible reverse currents than the detecting photodiode. As a result, the total current of the multi junction photodetector is dictated by the detecting photodiode. Therefore, a total current can be read by, for example, read-out circuits to give the optical signal strength at that specific wavelength of the detecting photodiode. By using an algorithm one can use such multi junction photodetectors to detect different wavelengths and to take multicolor images.
US08350205B2 Optical receiver comprising breakdown-voltage compensation
The present invention enables the detection of light using an APD that has high gain and/or a wide range of operating temperature. A first APD is biased with a voltage bias that is controlled based on the breakdown voltage of a second APD, which is thermally coupled with the first APD. Changes in the breakdown voltage of the second APD due to aging, temperature chances, and the like, are reflective of changes in the breakdown voltage of the first APD. As a result, the first APD can be operated with greater stability and reliability at high gain and over larger temperature excursions than APDs known in the prior art.
US08350201B2 Systems, apparatus and methods to compensate for roll orientation variations in missile components
The roll orientation of a thrust vector control (TVC) or other missile section is measured and used to compensate the operation of the control surface. A measurement of a roll orientation of the control surface relative to the missile is obtained from a detector, memory or other source. Compensated control commands are determined at least in part based upon the measurement to account for the roll orientation of the control surface relative to the missile, and the compensated control command is provided to thereby actuate the control surface during operation of the missile.
US08350200B1 Passive aerosurface adjustment for static margin management
A missile and a method for reducing the required control forces during the flight of a missile, comprising providing to the missile movable parts that adjust center of pressure of the missile as they move and as fuel in the missile is consumed, moving the movable parts so as to continuously move the center of pressure toward the moving center of gravity of the missile.
US08350199B2 Apparatus to reduce thrust oscillations in a launch vehicle
A launch vehicle comprising a casing, a solid propellant, a channel, a geometric feature, and a suppression structure. The solid propellant is located within the casing. The channel is through the solid propellant, and the geometric feature is in the channel. The suppression structure is located around a centerline for the channel and located upstream in a flow path from the geometric feature.
US08350193B2 Oil water mixture heating apparatus
An oil water mixture heating apparatus comprises a metal outer barrel with a helical trough formed inside, a metal inner barrel held in the metal outer barrel to form a helical passage with the helical trough, a first and a second guide cap coupled on two sides of the metal outer and inner barrels, a first and a second seal cap coupled respectively on the first and second guide caps, a first and a second holder fixedly located on outer sides of the two seal caps and an electric heater encasing the metal outer barrel. When combustible oil or oil water mixture enters the helical passage and are heated by the electric heater, the oil or oil water mixture also is constantly blended in the helical passage so that it is heated rapidly to a required temperature and forms a finer oil water mixture.
US08350192B2 Dual fan convection performance divider
An oven includes an interior cavity and a convection heating system for developing a flow of heated air within the interior cavity. The convection heating system includes a plurality of fans to provide a plurality of airflows, and a single convection heating element for heating the plurality of airflows. A shroud is arranged in covering relationship over the convection heating system and includes at least one intake aperture, and a plurality of exhaust apertures for discharging air from the plurality of fans back into the interior cavity. A baffle is located within the shroud and generally between adjacent ones of the plurality of fans. The baffle inhibits mixture of the airflows of each of the fans within the shroud. In one example, a first fan provides a first airflow, a second fan providing a second airflow, and the baffle inhibits mixture of the first and second airflows within shroud.
US08350190B2 Ceramic electrode for gliding electric arc
A ceramic electrode for a gliding electric arc system. The ceramic electrode includes a ceramic fin defining a spine, a heel, and a tip. A discharge edge of the ceramic fin defines a diverging profile approximately from the heel of the ceramic fin to the tip of the ceramic fin. A mounting surface coupled to the ceramic fin facilitates mounting the ceramic fin within the gliding electric arc system. One or more ceramic electrodes may be used in the gliding electric arc system or other systems which at least partially oxidize a combustible material.
US08350183B2 Method for laser machining transparent materials
A method for machining a transparent material by the non-linear absorption of pulsed laser radiation, in the region of a laser focus, includes the following steps: a laser wavelength of between 300 and 1000 μm is selected; and laser impulses having a temporally flat beam profile are applied. The method is characterized in that the irradiation intensity is selected from an interval pre-determined for the material to be machined, in which plasma is formed without plasma luminescence. An apparatus for laser treating a transparent material includes structure to set an irradiance and inspect the treatment as being within a defined interval.
US08350181B2 Gas distribution ring assembly for plasma spray system
A gas distribution ring assembly for a plasma spray system includes a gas distribution ring including a plurality of openings allowing a gas to pass to an inner diameter thereof. The assembly also includes a separate positioning ring axially aligned with the gas distribution ring between the gas distribution ring and an electrically charged outlet of the plasma spray system.
US08350178B2 Method of welding duplex stainless steel strip for the production of an armouring layer of a flexible pipe
The invention relates to a method of providing a duplex stainless steel strip for an armouring layer of a flexible pipe, said method comprising providing at least two duplex stainless steel pieces each having an end-face, welding said end-faces of said two pieces of duplex stainless steel together to form a welded interface section using resistance welding, such as dual upset welding or flash welding, and providing a controlled cooling of said welded interface section. The duplex stainless steel strip should preferably be heated to a temperature of at least about 1100° C., preferably at least about 1200° C., such as at least about 1500° C. in said interface section, and the controlled cooling of said welded interface section preferably comprises prolonging the cooling of the interface section preferably at least for the cooling from about 800° C. to about 600° C., more preferably at least for the cooling from about 1100° C. to about 600° C.
US08350169B2 Three-positions disconnector for medium voltage panels
A three-positions disconnector comprising, for each phase an insulating casing which comprises a first and a second cavity separated by an insulated partition wall, a through hole being present in said partition wall between said first and second cavity. The first cavity houses: a first fixed contact electrically connected to a corresponding branch conductor (of a bus-bar system; at least a portion of a movable contact pivotally mounted on a support positioned in the first cavity and electrically connected to a first electrical terminal positioned in said second cavity. The disconnector further comprises, for each phase, a second fixed contact suitable for ground connection. Also, the disconnector comprises an operating mechanism and a kinematical chain linking the movable contact with the operating mechanism; the movable contact is movable between a first position in which it is coupled to the first fixed contact, a second position in which it is isolated from both the first and second fixed contacts, and a third position in which it coupled to the second fixed contact.
US08350165B2 Flexible tablet
A flexible tablet is disclosed, and particular disclosed a flexible tablet having both of a hard housing structure and a soft housing structure. The flexible tablet fix a control board in the hard housing structure for preventing the control board form bending and break resulting from external force. In the flexible tablet, the soft housing structure is applied instead of the hard housing of a conventional tablet to fix a sensing board therein. Therefore, the soft housing structure and the sensing board are integrated to form a flexible writing member of the flexible tablet. As a consequence of foregoing structure, the tablet is flexible and convenient to be stored and carried, and the cost of the tablet is reduced.
US08350162B2 Connecting structure for circuit board and connecting method using the same
Disclosed is a connection structure for a circuit board using a solder bump to arrange circuit boards. The circuit board connection structure includes a solder bump prepared on one of two circuit boards and a perforated part formed at the other of the circuit boards to receive the solder bump. Facing both circuit boards towards each other and inserting the solder bump into the perforated part, the circuit boards are desirably arranged.
US08350161B2 Circuit board and structure using the same
According to one of the invention, a circuit board comprises a conductive layer. The conductive layer includes a first land portion, a second land portion apart from the first land portion in a plan view, and a line portion connecting the first land portion and the second land portion to each other. The line portion includes lead portions through which a current is to flow and an opening portion arranged between the lead portions. The opening portion penetrates the conductive layer in a thickness direction.
US08350160B2 Structure, electronic device, and method for fabricating a structure
A structure includes a conductive film (12) provided in an underlying layer (10); and a carbon nanotube bundle (20) including a plurality of carbon nanotubes each having one end connected to the conductive film (12), wherein, at other end side of the carbon nanotube bundle (20), at least carbon nanotubes allocated at outer side of the carbon nanotube bundle (20) extend with convex curvatures toward the outside of the carbon nanotube bundle (20), and the convex curvatures of the carbon nanotubes allocated at the outer side of the carbon nanotube bundle are larger than those of inner side of the carbon nanotube bundle (20), and diameters of the carbon nanotube bundle (20) decrease toward the other end of the carbon nanotube bundle (20).
US08350158B2 Tape wiring substrates and packages including the same
Example embodiments are directed to a tape wiring substrate including a film having an upper surface including a chip mounting area, the chip mounting area further including an inner area and a peripheral area, the film further including a lower surface, and vias penetrating the film, the vias being located in the inner area, an upper metal layer on the upper surface of the film and connected to electrode bumps of a semiconductor chip, and a lower metal layer on the lower surface of the film. Example embodiments are directed to a tape wiring substrate including a film having an upper surface including a chip mounting area, a lower surface, and vias penetrating the film, an upper metal layer on the upper surface of the film and connected to electrode bumps of a semiconductor chip, and a lower metal layer on the lower surface of the film, the vias being located outside of the chip mounting area. Example embodiments are directed to packages including tape wiring substrates.
US08350157B2 Printed circuit board
A printed circuit board includes a layer. A layer of copper is covered on a surface of the layer. A through hole passes through the printed circuit board. An approximately C-shaped thermal engraving is defined in the surface of the layers, surrounding the through hole and without being covered by the layer of copper. An opening of the thermal engraving faces an output terminal of the power supply.
US08350154B1 Universal wall plate mount
A wall plate comprising a housing defining a wall plate perimeter, a pair of mounting members integral to the housing, at least one mounting flange having an aperture and being removably secured to the pair of mounting members, and a mounting screw for securing an electrical device to the at least one mounting flange.
US08350153B1 Locking mechanism for joining sections
The present invention relates to a locking mechanism for joining sections to enable plates to be separated, then reconnected and securely interlocked. A variety of plate configurations may be utilized with the locking mechanism in applications such as cable pass-through, electrical wiring, or any application in which the engagement of structures is desired. The locking mechanism embodying the principles of the present invention includes outwardly extending finger detents adjacent to the cantilever tabs of each plate that slideably engage the bottom surface of an opposing plate section and create resistive forces between the interlocked cantilever tabs. The addition of the finger detents increases the inter-mating strength of the locked plate by providing a resistive moment arm to resist outward forces acting to separate the plate sections. The cantilever tabs further include a locking lip that engages a locking means of an opposing plate section to resist lateral forces acting to separate the plate.
US08350150B2 Enclosure of electronic device
An enclosure of an electronic device includes a plate. The plate defines a number of through holes. Each through hole has a pair of tabs connected to each other and with the through hole. Each pair of tabs are slantingly bent towards an inside of the enclosure. The enclosure with the shields can shield the electronic device from electro-magnetic interference.
US08350149B2 Housing assembly for electronic device
A housing assembly includes a first housing having first positioning holes, a second housing having second positioning holes, and an assembly unit connected between the first and second housings and including two assembly parts. Multiple engaging devices each include a first engaging member and a second engaging member. The engaging devices are connected to the first and second positioning holes by first and second resilient members. An operation device is connected to the engaging devices and includes first and second release members which are respectively connected to the assembly parts. A link is connected to the assembly unit and connected with the first and second release members. An operation member is connected to the link to move the first or second release members of each engaging device and disengage the first and second release members from the first or second positioning holes of the first or second housings.
US08350144B2 Hybrid photovoltaic cell module
A hybrid photovoltaic cell module includes a substrate and a photopolymer composition disposed on the substrate. The photopolymer composition includes an organic photopolymer, a plurality of nanoparticles, and a dendrimer that disperses the nanoparticles in the composition. The dendrimer has a number average molecular weight of from 300 to 10,000 g/mol and a core having a carbon atom directly bonded to X1 and X2 and two —CH2 groups. X1 is a hydrogen atom, a functional group, or a chain including a functional group. X2 is a chain including a functional group that is the same or different from the functional groups of X1. Each —CH2 group is bonded to a chain that independently includes a functional group that is the same or different from said functional groups of X1 and X2. The module is formed using a method that includes the step of disposing the photopolymer composition on the substrate.
US08350139B2 Device for adjusting and blocking a snare band
A snare band adjustment and locking device of a snare drum includes a mechanism for adjusting first, second and third settings, a first setting wherein the snare band is removed from the snare head, a second setting wherein the snare band has a maximum, predetermined contact pressure with the snare head, and a third setting wherein the contact pressure of the snare band with the snare head can be continuously varied between the contact pressure in the first and second settings. The adjustment mechanism is operated in the third setting via a foot pedal and a cable running through a control member which determines by its tension the spacing between the control member and a control lever pretensioned by a compression spring.
US08350137B1 Maize variety hybrid X8K862
A novel maize variety designated X8K862 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X8K862 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X8K862 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X8K862, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X8K862. This invention further relates to methods for producing maize varieties derived from maize variety X8K862.
US08350132B1 Inbred maize variety PHE64
A novel maize variety designated PHE64 and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PHE64 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PHE64 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PHE64 or a trait conversion of PHE64 with another maize variety. Inbred maize varieties derived from maize variety PHE64, methods for producing other inbred maize varieties derived from maize variety PHE64 and the inbred maize varieties and their parts derived by the use of those methods.
US08350130B2 Inbred corn line AB7
An inbred corn line, designated AB7, is disclosed. The invention relates to the seeds of inbred corn line AB7, to the plants and plant parts of inbred corn line AB7 and to methods for producing a corn plant, either inbred or hybrid, by crossing inbred line AB7 with itself or another corn line. The invention further relates to methods for producing a corn plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other inbred corn lines derived from inbred corn line AB7.
US08350128B2 Soybean cultivar S080103
A soybean cultivar designated S080103 is disclosed. The invention relates to the seeds of soybean cultivar S080103, to the plants of soybean S080103, to plant parts of soybean cultivar S080103, and to methods for producing a soybean plant produced by crossing soybean cultivar S080103 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars, or breeding cultivars, and plant parts derived from soybean variety S080103, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar S080103, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing the cultivar S080103 with another soybean cultivar.
US08350124B2 Root Specific expression promoter from Capsicum annuum aquaporin gene and uses thereof
The present invention relates to a root specific plant expression promoter and 5′-untranslated region (5′-UTR) from Aquaporin gene of Capsicum annuum, a root specific plant expression vector comprising the same, a process for root specif-expression of a foreign gene by using said vector, and a plant transformed with said vector and seeds of the transformed plant. According to the present invention, the root specific expression promoter of the present invention can be used for root specific expression of a gene that is introduced to a transformed plant, compared to CaMV35S promoter from cauliflower mosaic virus by which gene expression is promoted in entire tissues of a plant. Consequently, the claimed invention can be advantageously used for the development of a transformed plant which is desired to be used for production of a useful material in a plant root.
US08350111B2 Method for producing cumene
One exemplary embodiment can be a method for processing polyisopropylbenzene for producing cumene. The method can include passing a transalkylation feed stream to a transalkylation zone, and passing a reaction product to a separation zone. Typically, the separation zone produces a stream including di-isopropylbenzene, tri-isopropylbenzene, and one or more heavy compounds. Moreover, the stream may include at least about 0.7%, by weight, of the one or more heavy compounds based on the weight of the di-isopropylbenzene, tri-isopropylbenzene, and the one or more heavy compounds in the stream, and at least a portion of the stream is recycled to the transalkylation zone.
US08350110B2 Heavy alkylbenzene transalkylation operating cost reduction
A process for increasing the production of monoalkylbenzenes is presented. The process includes utilizing a transalkylation process to convert dialkylbenzenes to monoalkylbenzenes. The transalkylation process recycles a portion of the effluent stream from the transalkylation reactor back to the feed of the transalkylation reactor. The recycled dialkylbenzenes and a portion of the recycled benzene are converted to monoalkylbenzenes.
US08350109B2 Production of styrene from ethylbenzene using azeotropic vaporization and low overall water to ethylbenzene ratios
A process for dehydrogenation of alkylaromatic hydrocarbon, including: contacting a reactant vapor stream, comprising an alkylaromatic hydrocarbon and steam and having a first steam to alkylaromatic hydrocarbon ratio, with a dehydrogenation catalyst to form a vapor phase effluent comprising a product hydrocarbon, the steam, and unreacted alkylaromatic hydrocarbon; feeding at least a portion of the effluent to a splitter to separate the product hydrocarbon from the unreacted alkylaromatic hydrocarbon; recovered from the splitter as bottoms and overheads fractions, respectively; recovering heat from a first portion of said overheads fraction by indirect heat exchange with a mixture comprising alkylaromatic hydrocarbon and water to at least partially condense said portion and to form an azeotropic vaporization product comprising alkylaromatic vapor and steam having a second steam to alkylaromatic hydrocarbon ratio; and combining the azeotropic vaporization product with additional alkylaromatic hydrocarbon and additional steam, together or separately, to form the reactant vapor stream.
US08350107B2 Selective isomerization and oligomerization of olefin feedstocks for the production of turbine and diesel fuels
A process for converting alcohol feedstocks to diesel/turbine fuels.
US08350101B2 Method for preparing vinylidene fluoride
The present invention relates to the method for obtaining vinylidene fluoride and the subject matter thereof is more particularly the production of vinylidene fluoride by pyrolysis of 1,2-dichloro-2,2-difluoroethane in the presence of hydrogen at a temperature of greater than or equal to 400° C.
US08350099B2 Fluorovinyl ether functionalized aromatic diesters, derivatives thereof, and process for the preparation thereof
Disclosed are fluorovinyl ether functionalized aromatic diesters and derivatives thereof. The compounds disclosed have utility as functionalized monomers and comonomers in polyesters, polyamides, and the like. It has been found that incorporation of the monomers into polymers provides improved soil resistance to shaped articles produced from the polymers.
US08350097B2 Therapeutic compounds
A (−)-stereoisomer of formula (I): (formula I), wherein X is H or F; or a pharmaceutically acceptable salt or pro drug thereof, is useful as an anesthetic.
US08350093B2 Methylated curcumin-resveratrol hybrid molecules for treating cancer
Methylated curcumin-methoxystilbene hybrid molecules that have particular use in treating cancer.
US08350090B1 Processes for preparing cyclopentenones and cyclopentenones for the synthesis of benzindene prostaglandins
The present invention provides novel processes of preparing racemic and optically active cyclopentenones of Formula I: The invention also provides novel cyclopentenones of formula I in racemic or optically active form.
US08350089B2 Yield-efficient process for the production of highly pure 2-methyl-1,4-naphthoquinone and its derivatives
The present invention discloses a process for the production of 2-methyl-1,4-naphthoquinone and its bisulfite adducts, comprising the following steps: a) oxidizing 2-methyl-naphthalene (2-MNA) to achieve an organic phase containing 2-methyl-naphthoquinone (2-MNQ) and 6-methyl-naphthoquinone (6-MNQ); b) subjecting said organic phase to treatment with an aqueous solution of a bisulfite salt to extract preferentially the 6-MNQ isomer from the organic phase; c) separating said organic phase from the aqueous phase; d) subjecting the organic phase of process step c) to a second bisulfidation step with an aqueous solution of a bisulfite salt, resulting in an organic phase containing 2-MNA and trace amounts of 2-MNQ and an aqueous phase containing 2-MSB and trace amounts of 6-MSB; e) optionally removing interfering bisulfite ions from the aqueous phase of process step c); f) raising the pH of the aqueous phase from step c) or e) to higher than 8.5 in the presence of a solvent resulting in an organic phase containing 2-MNQ; g) combining the organic phase from step f) with the organic phase being treated in the process step d); h) recycling the organic phase from step d) back to step a) to be used as solvent for the oxidation reaction of 2-MNA.
US08350085B2 Cocrystallization
The present disclosure relates to novel cocrystals and novel methods for cocrystallization. In particular, the disclosure includes cocrystals comprising a salt of an active agent, such as a chloride salt of an active pharmaceutical ingredient. The present disclosure also relates to methods of preparing cocrystals and methods for screening for solid state phases.
US08350084B2 Alpha-(N-sulfonamido)acetamide compound as an inhibitor of beta amyloid peptide production
The present invention provides a novel alpha-(N-sulfonamido)acetamide compound, its pharmaceutical composition, processes thereof and a method for the treatment of Alzheimer's disease and other conditions associated with β-amyloid peptide.
US08350077B2 Amides of creatine, method of their preparation, and remedy possessing a neuroprotective activity
The invention relates to pharmaceutical chemistry notably to new biologically active substances (BAS) and their properties. In particular, the invention relates to Creatine derivatives having a general formula: NH═C(NH2)—N(CH3)—CH2—CO—NH—R*X, wherein R—amino acid residue of aliphatic, aromatic or heteroaromatic L-amino acid or its derivative representing a salts of amino acid, amino acid esters, amino acid amides or peptides; X—lower organic or mineral acid or water. New substances are prepared by interaction of aforesaid amides of sarcosine having a general formula of HN(CH3)—CH2—CO—NH—R*X, wherein: R is amino acid residue or substituted amino acid residue; X is low-molecular-weight organic acid or mineral acid or water, with a guanidinylating agents with the in organic solvents at temperature not exceeding 50° C. New chemical compounds can be used as a remedy possessing a neuroprotective activity.
US08350071B2 Decantation improvement in a method of producing alkyl esters from vegetable or animal oil and an aliphatic monoalcohol
The present invention describes a method of producing fatty acid alkyl esters and glycerin implementing, in a reaction section, a set of transesterification reactions between a vegetable or animal oil and an aliphatic monoalcohol, and using a heterogeneous solid catalyst, comprising: a) a stage of recontacting the effluent coming from the reaction section, and separated from the excess alcohol, with a glycerin phase, b) a stage of mixing said effluent with said glycerin phase, and c) a glycerin phase decantation stage. The supernatent ester phase obtained after decantation is then optionally sent to a coalescer, also allowing separation of the glycerin, then to a purification stage by adsorption on solids.
US08350067B2 Compounds useful in the synthesis of halichondrin B analogs
In general, the invention features compounds useful for the synthesis of analogs of halichondrin B, such as eribulin or pharmaceutically acceptable salts thereof, e.g., eribulin mesylate. Exemplary compounds are of formula (I), (II), or (III):
US08350064B2 Fluorescent xanthenes and white light fluorophores
Xanthene compounds are disclosed having fluorescence at multiple wavelengths. Also disclosed are methods for their synthesis and use. Some of the compounds fluoresce at three wavelengths, emitting white light. Uses include the imaging of biological tissues, illumination, and display technologies. Many of the compounds have large Stokes shifts, and are resistant to photobleaching. The fluorescence may be readily distinguished from that of endogenous fluorophores, and from that of most existing, commercially-available fluorescent probes. The compounds are well suited for use in “multiplexing” techniques. They exhibit clear isosbestic and isoemissive points, and have broad absorption and emission ranges.
US08350059B2 Intermediates and methods for making zearalenone macrolide analogs
Disclosed herein are methods and intermediates useful in the preparation of macrolides, e.g., compounds of formula (IV) wherein R1-R12 are as defined herein.
US08350058B2 Method for producing alkenyl succinic anhydrides
The invention relates to a method for producing alkenyl succinic anhydrides of formula (1), in which R represents a C4 to C250 alkylene radical that can be linear or branched. The method involves the reaction of maleic acid, maleic anhydride, fumaric acid or esters thereof and an alkene which contains 4-250 carbon atoms at from 150 to 250° C. in the presence of a synergistic mixture of a primary antioxidant, a secondary antioxidant, and a metal deactivator.
US08350055B2 Heteroaryl-substituted 1,3-dihydroindol-2-one derivatives and medicaments containing them
The present invention relates to novel 1,3-dihydroindol-2-one (oxindole) derivatives of the formula (I) in which A, R3, R4, R5, R6, and R7 are defined according to claim 1, and to medicaments containing them for the treatment of diseases. In particular, the novel oxindole derivatives can be used for the control and/or prophylaxis of various vasopressin-dependent or oxytocin-dependent diseases.
US08350054B2 Optical filter
An optical filter containing at least one naphtholactam derivative represented by general formula (I), wherein X is oxygen or sulfur; R1, R2, R3, R4, R5, R6, and Y are each hydrogen, halogen, nitro, cyano, aldehyde, carboxyl, hydroxyl, —NRR′, organosilyl, optionally substituted C1-C30 alkyl, optionally substituted C6-C30 aryl, or optionally substituted C7-C30 arylalkyl; and R and R′ are each hydrogen, optionally substituted C1-C30 alkyl, or optionally substituted C6-C30 aryl.
US08350052B2 Process for the preparation of 1-benzyl-3-hydroxymethyl-1H-indazole and its derivatives and required magnesium intermediates
The present invention relates to the process for the conversion of 1-benzyl-3-hydroxymethyl-1H-indazole according to formula (II), to the 1-benzyl-3-hydroxylmethyl-1H-indazole according to formula (I).
US08350051B2 Process for producing alpha-hydroxyketone compound
A process for producing an α-hydroxyketone compound, which comprises subjecting an aldehyde compound to a coupling reaction in the presence of an alkoxyimidazolidine compound represented by the formula (1) wherein R1? and R2? independently represent a hydrogen atom, etc., R3? and R4? independently represent a substituted or unsubstituted aryl group, etc. and R5? represents an alkyl group.
US08350050B2 Bis-(1(2)H-tetrazol-5-yl) amine and production method therefor
High-quality bis-(1(2)H-tetrazol-5-yl)amine and a method for easily, safely, and inexpensively producing the compound are provided. The method for producing bis-(1(2)H-tetrazol-5-yl)amine includes the steps of heating to 50 to 120° C. a solution mixture in which a necessary amount of an azide salt and a dicyanamide salt in an amount corresponding to 1 to 80 wt % of a necessary amount are added to a solvent, adding an acid in an amount of 1.54 to 2.22 chemical equivalents of the dicyanamide salt in the solution mixture to carry out a reaction at 50 to 120° C., and then adding an acid and a dicyanamide salt solution in which the remaining dicyanamide salt is dissolved in a solvent to promote the reaction. Bis-(1(2)H-tetrazol-5-yl)amine is obtained according to the production method.
US08350044B2 Pesticidal compositions
This document discloses molecules having the following formula (“Formula I”):
US08350042B2 Antiviral compounds for the treatment of HCV infection
Disclosed are compounds and methods of synthesis of Formula I for the development of antiviral drugs for the treatment of HCV infection.
US08350038B2 Fluorescence quencher molecules
Disclosed are pyridinyl-isoquinoline-dione derivatives, methods of producing these derivatives, conjugates comprising the pyridinyl-isoquinoline dione derivatives and (i) a solid support, or (ii) a biomolecule, methods of producing these conjugates as well as the use of these conjugates as quenchers in fluorescence resonance energy transfer (FRET).
US08350037B2 Thieno-pyridine derivatives as MEK inhibitors
A series of thieno[2,3-b]pyridine derivatives which are substituted in the 2-position by a substituted anilino moiety, being selective inhibitors of human MEK (MAPKK) enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, proliferative (including oncological) and nociceptive conditions.
US08350032B2 Integrated photoactive agents for real-time monitoring of hemostasis
The present invention discloses a number of photoactive compounds designed to bind and inhibit serine proteases. Compounds disclosed herein may be utilized in a number of appropriate medical diagnostic and/or therapeutic procedures such as the monitoring of hemostasis, imaging and/or treatment of vulnerable plaques, and/or tumor imaging and/or treatment.
US08350031B2 Processes for the synthesis of levocetirizine and intermediates for use therein
The present invention provides a compound of formula (IV) wherein R is Cl, Br, NO2, OH or OR′, and R′ is alkyl, and its use in the synthesis of levocetirizine, including its use in the synthesis of (−)-1-[(4-chlorophenyl)-phenylmethyl]piperazine, an intermediate useful in the synthesis of levocetirizine. The present invention also provides compounds (II) and (III) which are useful in the synthesis of compound (IV).
US08350030B2 Process for producing 5-fluoro-1-(2R, 5S)-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine
Disclosed herein an improved process for producing 5-Fluoro-1-(2R,5S)-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine and its pharmaceutical acceptable salts.
US08350029B2 Process for the preparation of gefitinib
There is provided a compound of formula III, and a process for preparing a compound of formula V comprising converting a compound of formula III to the compound V, wherein X is fluoro, chloro, bromo or iodo. There is also provided a process for preparing a compound of formula XI comprising converting a compound of formula X to the compound XI. The compounds V and XI so prepared may be used in a process for preparing gefitinib.
US08350028B2 2-aminoquinolines
The present invention is concerned with 2-aminoquinoline derivatives of formula I wherein R1 and R2 are as described herein and pharmaceutically acceptable salts thereof, pharmaceutical compositions containing them, and methods for their manufacture. These compounds are 5-HT5A receptor antagonists, useful for the prevention and/or treatment of depression, anxiety disorders, schizophrenia, panic disorders, agoraphobia, social phobia, obsessive compulsive disorders, post-traumatic stress disorders, pain, memory disorders, dementia, disorders of eating behaviors, sexual dysfunction, sleep disorders, abuse of drugs, motor disorders such as Parkinson's disease, psychiatric disorders or gastrointestinal disorders.
US08350023B2 Crystalline polymorphs of gemcitabine base
The present application provides several crystalline forms of gemcitabine base and methods of making the same.
US08350020B2 Compositions and methods related to mRNA translational enhancer elements
Provided are mRNA translational enhancer elements (TEEs), e.g., SEQ ID NOs:1-35. Also provided are translational enhancer polynucleotides that comprise one or more of the specific TEEs exemplified herein or their variants, homologs or functional derivatives. Further provided are expression vectors comprising such TEEs or translational enhancer polynucleotides, as well as host cells and expression systems that harbor such vectors.
US08350019B2 Recombinant Plasmodium falciparum merozoite surface proteins 4 and 5 and their use
Accordingly, the invention provides constructs in which the nucleic acids encoding Plasmodium falciparum MSP4 and MSP5, and the resulting polypeptides, have been modified. More particularly, this invention provides constructs encoding recombinant MSP4 and MSP5 polypeptides, which are expressed as soluble, secreted polypeptides in a baculovirus-insect cell expression system. It was surprisingly found that the recombinant polypeptides contain an EGF-like domain at the C-terminus that is properly folded in the polypeptide.
US08350018B2 Polynucleotides of Haemophilus parasuis and its use
The present invention relates to Haemophilus parasuis polynucleotides produced by recombinant technology. It also relates to polypeptides that are expressed by said polynucleotides and also to a vaccine against H. parasuis that comprises said polypeptides. In another aspect, the invention also relates to the use of polynucleotides to determine if a strain of H. parasuis is virulent or avirulent.
US08350014B2 Preparation of diazo and diazonium compounds
A method for making diazo-compounds, diazonium salts thereof and other protected forms of these compounds. Diaz-compounds are prepared by reaction of a tertiary phosphine reagent carrying a reactive carbonyl group with an azide. The reaction can also generate an acyl triazene which can be converted thermally or by addition of base to form the diazo-compound or the acyl triazene can be isolated. The method is particularly useful for conversion of azides carrying one or more electron withdrawing groups to diazo-compounds. The method can be carried out in aqueous medium under mild conditions and is particularly useful for conversion of azido sugars to diazo-compound and diazonium salts thereof under physiological conditions. Tertiary phosphine reagents, particularly those that are water-soluble, and precursors for preparation of the reagents are provided.
US08350012B2 Inverse agonist monoclonal antibody that suppresses thyrotropin receptor constitutive activity
This invention describes monoclonal antibodies that suppress thyrotropin receptor constitutive activity and methods of using the antibodies to treat thyroid related diseases; particularly hyperthyroidism and thyroid cancer.
US08350011B2 Antibodies to ErbB2
The present invention relates to antibodies including human antibodies and antigen-binding portions thereof that specifically bind to ErbB2, preferably human ErbB2. In another embodiment, the antibodies or antigen-binding portions thereof inhibit ErbB2. The invention also relates to antibodies that are chimeric, bispecific, derivatized, single chain antibodies or portions of fusion proteins. The invention also relates to isolated heavy and light chain immunoglobulins or portions thereof derived from human anti-ErbB2 antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of using the antibodies and compositions for diagnosis and treatment. The invention also provides gene therapy methods using nucleic acid molecules encoding the heavy and/or light immunoglobulin molecules that comprise the human anti-ErbB2 antibodies. The invention also relates to transgenic animals or plants comprising nucleic acid molecules of the present invention.
US08350005B2 Method and means for enrichment removal and detection of listeria
The present invention relates to polypeptide fragments of endolysin Ply511, which recognize and bind listeria irrespective of the serotype but which have no cell wall hydrolysing enzymatic activity. The invention further relates to methods for enrichment, removal, and detection of listeria.
US08350004B2 Peptide nanostructures and methods of generating and using the same
A tubular or spherical nanostructure composed of a plurality of peptides, wherein each of the plurality of peptides includes no more than 4 amino acids and whereas at least one of the 4 amino acids is an aromatic amino acid.
US08350002B2 Process for producing ethylene/vinyl alcohol copolymer
A process is provided for producing an ethylene/vinyl alcohol copolymer by which impurities such as catalyst residue and by-products and solvent are removed to a high degree. A high-quality, homogeneous product can be efficiently produced by including a washing step including: introducing a paste containing an ethylene/vinyl alcohol copolymer and an alcohol into a washing tank; applying a shear force to the paste to knead the paste while contacting the paste with washing water so that a surface of the paste is repeatedly displaced by an inner part thereof; and discharging the alcohol to an outside of the tank together with the washing water to obtain a water-containing ethylene/vinyl alcohol copolymer composition having a small alcohol content.
US08349997B2 Method for production of block copolymer
Disclosed is a method for producing a block copolymer which comprises two or more blocks composed of aromatic units having different basic structures from each other and has a high molecular weight, a narrow chain length distribution and a narrow molecular weight distribution. Also disclosed is a block copolymer produced by the method. The method for producing a block copolymer comprises the step of sequentially reacting two or more aromatic compounds which are selected from aromatic compounds represented by a specific general formula and are different in the group Ar, in the presence of a nickel complex containing a phosphine compound represented by a specific general formula or a palladium complex containing a phosphine compound represented by a specific general formula to thereby form blocks comprising the aromatic compounds sequentially, wherein the two or more aromatic compounds are reacted in descending order of parameter of aromatic ring charge.
US08349990B2 Chain scission polyester polymers for photoresists
Polymers for extreme ultraviolet and 193 nm photoresists are disclosed. The polymers comprise a photoacid generator (PAG) residue, an acid cleavable residue and a diacid joined by ester linkages. The polymers include a photoacid generating diol, a diacid and an acid table diol.
US08349979B2 Liquid admixture composition
An admixture comprises an aqueous composition of a) a copolymeric dispersing component, b) an antifoaming agent component, c) a surfactant component, and d) water. The components may be a blend or physically or chemically attached and result in a stable liquid system that can be used as a dispersing agent for a calcium sulfate compound containing construction chemicals composition.
US08349976B2 Copolymers containing perfluoroalkyl groups and aqueous dispersions thereof
Copolymers which are composed of at least 4 monomers, including (meth)acrylate compounds containing perfluoroalkyl groups, are suitable for the treatment of fiber materials. The copolymers are usually used here in the form of aqueous dispersions. The fiber materials are in particular fabrics, for example made of polyolefin. Treatment with the copolymers imparts to them oil- and water-repellent properties and also repellent properties toward low molecular weight alcohols.
US08349972B2 Paint compositions, a method of paint finishing and painted objects
Disclosed herein is a paint composition comprising a hydroxyl group containing resin (A), comprising structural units based on 2,2-dimethylolalkanoic acid, having a hydroxyl group value of from 200 to 400 mgKOH/g, and comprising less than 25 weight % in the resin solid fraction of structural units based on a lactone compound; a hydroxyl group containing resin (B), having a hydroxyl group value from 50 to 200 mgKOH/g, and comprising from 25 to 75 weight % in the resin solid fraction of structural units based on a lactone compound; and a crosslinking agent (C) comprising at least two OH-reactive functional groups per molecule; wherein the resin solid fraction weight ratio (A)/(B) of the hydroxyl group containing resin (A) and the hydroxyl group containing resin (B) is from 90/10 to 10/90.
US08349966B2 Marine coatings
Marine coatings including cationic polymers hydrolyzable to nonfouling zwitterionic polymers, coated marine surfaces, and methods for making and using the marine coatings.
US08349965B2 Fluororubber composition capable of forming crack-resistant seal and crack-resistant seal formed from the composition
A fluororubber composition according to the present invention contains 0.1 to 3 parts by weight of a polyol compound, 0.1 to 4 parts by weight of a peroxide crosslinking agent, and 1 to 9 parts by weight of a co-crosslinking agent per 100 parts by weight of a peroxide-crosslinkable fluoropolymer. A crack-resistant seal according to the present invention contains a crosslinked fluoropolymer and a polyol compound. The crack-resistant seal according to the present invention can be formed by crosslinking the fluororubber composition, and the resultant crack-resistant seal has particularly high crack resistance. With the fluororubber composition according to the present invention, a durable crack-resistant seal having high plasma resistance, crack resistance, and compression set and that produces few particles can be formed at low cost.
US08349963B2 Crosslinked elastic material formed from a linear block copolymer
An elastic material for use in an absorbent article is provided. The elastic material contains a crosslinked network formed from a linear block copolymer having a monoalkenyl aromatic midblock positioned between conjugated diene endblocks (e.g., butadiene-styrene-butadiene (“B-S-B”) triblock copolymer). Prior to crosslinking, such linear block copolymers have a relatively low viscosity and thus may be readily formed into a precursor elastic material (e.g., film, strands, web, etc.) that is subsequently crosslinked to achieve the desired elastic and mechanical properties. Crosslinking is typically achieved through the formation of free radicals (unpaired electrons) that link together to form a plurality of carbon-carbon covalent bonds at the conjugated diene endblocks.
US08349962B2 Acrylic pressure-sensitive adhesives with acylaziridine crosslinking agents
A pre-adhesive composition is described comprising an acid-functional (meth)acrylate copolymer and an acylaziridine crosslinking agent, which when crosslinked provides a pressure-sensitive adhesive and pressure-sensitive adhesive articles.
US08349956B2 Tire with a tread comprising an SNBR elastomer
The present invention relates to a tire having a tread comprising a rubber composition that comprises at least: as a first diene elastomer, between 5 and 25 phr of a styrene-nitrile-butadiene terpolymer (SNBR) having a nitrile monomer content between 4 and 18% by weight; a second diene elastomer other than SNBR; a reinforcing filler; a liquid plasticizer, the glass transition temperature of which is below −20° C. The invention makes it possible to improve the properties of rolling resistance and of grip on wet ground of tire treads.
US08349942B2 Intermediate transfer member
Described herein is an intermediate transfer member that includes a layer of phenoxy resin having dispersed therein graphene particles.
US08349939B2 Composites of inorganic and/or organic microparticles and nano-calcium carbonate particles
The present invention relates to composites, comprising inorganic and/or organic pigments and/or fillers in the form of microparticles, the surface of which is coated at least partially with finely divided nano-calcium carbonate with the help of binders based on copolymers comprising as monomers one or more dicarboxylic acids and one or more monomers from the group of diamines, triamines, dialkanolamines or trialkanolamines, a method for producing such composites, aqueous slurries thereof and their use in papermaking or in the field of paint and plastic production and the use of the inventive binders for coating the microparticles with nano-calcium carbonate.
US08349938B2 Process for making polyolefin compositions
A process of obtaining a thermoplastic composition formed from a polyolefin matrix is disclosed. The polyoelfin matrix comprises a polypropylene The process comprises (a) the formation of a viscoelastic mixture of the polypropylene and the lamellar mineral by heating and kneading the composition at a temperature at least equal to the working temperature of the polypropylene, (b) submitting the viscoelastic mixture to thermo-mechanical work, (c) eliminating volatile components from the viscoelastic mixture, and (d) transforming the viscoelastic mixture resulting from step (c) into a granulated material. The viscoelastic mixture is subjected during steps (a) and (b) to a weak and controlled rate of shearing of no more than 200 s−1 and the viscoelastic mixture is subjected in step (b) to at least one cycle of extension and relaxation in a dedicated zone which is at least 25% of the total length of at least one screw of a compounding extruder.
US08349934B2 Hardening composition and hardened product thereof
The present invention is directed to a hardening composition comprising silica fine particles (a), a (meth)acrylate (b) having two or more ethylenically unsaturated groups and being free from cyclic structure, a (meth)acrylate (c) having an ethylenically unsaturated group and having an alicyclic structure, a polymerization initiator (d) and black inorganic fine particles (e), wherein the silica fine particles (a) are surface-treated with a silane compound (f) represented by the following general formula (1) and a silane compound (g) represented by the following general formula (2): (in the formula (1), R1 represents a hydrogen atom or a methyl group, R2 represents an alkyl group having 1 to 3 carbon atoms or a phenyl group, R3 represents a hydrogen atom or a hydrocarbon group having 1 to 10 carbon atoms; q represents an integer of 1 to 6; and r represents an integer of 0 to 2, (in the formula (2), R4 is an alkyl group having 1 to 3 carbon atoms or a phenyl group which may have a substituent; R5 is a hydrogen atom or a hydrocarbon group having 1 to 10 carbon atoms; s is an integer of 0 to 6; and t is an integer of 0 to 2.
US08349932B2 Polyamide compositions with improved salt resistance and heat stability
Disclosed is a polyamide composition including at least one semi-aromatic copolyamide, said semi-aromatic copolyamide consisting essentially of about 25 to about 55 mole percent repeat units of the formula —C(O)(CH2)mC(O)NHCH2ArCH2NH—  (I) and about 45 to about 75 mole percent repeat units of the formula —C(O)(CH2)mC(O)NH(CH2)nNH—  (II) wherein m is 8, 10, and/or 12, n is 6, 10 and/or 12 and Ar is a meta-substituted benzene ring; and said polyamide has a melting point equal to or less than 225° C.; and 0.25 to 20 weight percent of one or more polyhydroxy polymer(s) having a number average molecular weight of at least 2000 and selected from the group consisting of ethylene/vinyl alcohol copolymer and poly(vinyl alcohol). Also disclosed are molded or extruded articles including the polyamide composition.
US08349931B2 Plastisols containing glycerol esters as plasticizers
Plastisols and organosols are provided that include plasticizers that include mono-, di- and triesters of glycerol. The plasticizers are good solvators for polyvinyl chloride and impart low plastisol and organosol viscosities.
US08349928B2 Metal particle dispersion structure, microparticles comprising this structure, articles coated with this structure, and methods of producing the preceding
A metal particle dispersion structure characteristically comprising (B) 0.005 to 100 weight parts of metal nanoparticles dispersed in (A) 100 weight parts of polymerized polymer, wherein the metal nanoparticles are metal particles obtained by mixing (b1) organohydrogenpolysiloxane and (b2) at least one metal compound which is soluble in component (b3) to uniformity in (b3) cyclic or chain dimethylpolysiloxane or at least one organic solvent.
US08349927B2 Scratch-resistant, impact-resistant polycarbonate moulding compositions having good mechanical properties II
The present invention relates to scratch-resistant, impact-resistant polycarbonate (PC) compositions and molding compositions which have good mechanical properties as well as high resistance to chemicals, to a process for their preparation, and to their use in the production of molded articles, in particular of casings for flat screen devices.
US08349926B2 Scratch-resistant, impact-resistant polycarbonate moulding compositions with good mechanical properties
The present invention relates to scratch-resistant, impact-resistant polycarbonate (PC) compositions and moulding compositions which have good mechanical properties and a high resistance to chemicals coupled with good flameproofing properties, and show improved flow properties during processing. The present invention furthermore relates to a process for the preparation of the compositions and their use for the production of shaped articles, in particular housings of flat screen apparatuses.
US08349924B2 Fire-resistant plasticizer for the plastic material industry and method of making thereof
The present invention relates to a group of new plasticizers for thermoplastics such as polypropylene, copolymers of polypropylene, polyethylene, polyethylene terephthalates, polystyrene and/or other polymers or mixtures of polymers containing organic and/or inorganic fillers, where the plasticizer is used for obtaining polyvinyl chloride like aspects and improved processability as well as for obtaining a better flexibility and a lower energy consumption during the processing step.
US08349919B2 Reinforced erosion control matrix and its application
A dry mixture for use with water has been developed to be used as an erosion control spray matrix for reducing erosion of sandy soils while awaiting development of a root system of plants to hold the soil in place. The dry erosion control mixture includes alpha-calcined calcium sulfate hemihydrate, a non-gypsum binder polymer; biodegradable fibers; and wood fiber mulch. An erosion control slurry is applied to an area of soil in need of erosion-control. After obtaining the dry erosion control mixture, it is mixed with water to form erosion control slurry. The ratio of the composition to the water is preferably from about 1:8 to about 1:12. Seed is distributed over the soil and the erosion control slurry is applied over the distributed seed.
US08349918B2 Organic siloxane composite material containing polyaniline/carbon black and preparation method thereof
An organic siloxane composite material containing polyaniline/carbon black and a preparation method thereof are disclosed. The organic siloxane composite material containing polyaniline/carbon black consists of a plurality of polyaniline/carbon black composites distributed in organic siloxane precursor while the organic siloxane composite material containing polyaniline/carbon black includes from 10 to 30 weight percent of polyaniline/carbon black composites. The preparation method of organic siloxane composite material containing polyaniline/carbon black includes the steps of: distributing a plurality of polyaniline/carbon black composites in organic siloxane precursor to produce a first solution; and adding a cross-linking agent into the first solution, after reaction with each other, an organic siloxane composite material containing polyaniline/carbon black is produced.
US08349916B2 Actinic energy radiation curable ink-jet ink, ink-jet recording method, and printed matter
The present invention provides an actinic energy radiation curable ink-jet ink exhibiting excellent ink storage stability, nozzle ink repellency, and ejection stability, and also exhibiting excellent curability, anti-abrasion properties, solvent resistance, flexibility, weather resistance, and substrate adhesion properties even under various ambience factors and irradiation conditions, as well as an ink-jet recording method and printed matter using the same. In an actinic energy radiation curable ink-jet ink containing a cationically polymerizable compound and a photo-cationic polymerization initiator, an actinic energy radiation curable ink-jet ink wherein a cationically polymerizable compound having a vinyl ether group as a reactive group is contained at 50.0% by mass or more and the halogen ion content is 1.0 μg/g of the ink-100 μg/g of the ink.
US08349911B2 Silane-based, aqueous coating system, production and use thereof
Production of a composition based on silanes for the scratch-resistant, hydrophobic, aqueous coating of metals, plastics, chemical products, ceramic materials, concrete and glass.
US08349908B2 Foamed materials comprising a matrix having a high highblock content and process for preparing them
Foamed material having a density of less than 100 kg/m3 and comprising a matrix material comprising a plurality of urea groups and having a hardblock content of more than 50% (hereinafter called matrix A); and a polymeric material which 1) has no groups which are able to form a urethane, urea or isocyanurate group with an isocyanate group, 2) is interpenetrating said matrix A, and 3) is a polymer having an average molecular weight of more than 500 which polymer comprises at least 50% by weight of oxyethylene groups based on the weight of this polymer (hereinafter called polymeric material B); and wherein the relative amount of all ingredients used to make said matrix A and of said polymeric material B, on a weight basis, ranges from 10:90 to 70:30 and process for making such materials.
US08349902B2 Pharmaceutical compositions useful for preventing and treating oncological diseases
The invention relates to pharmacology, medicine and oncology, in particular, to a class of chemical compounds, the structure of which corresponds to formula (I) and which can be used in pharmaceutical compositions for preventing and treating an extended range of oncological diseases, including, in the form of an anti-tumoral preparation and a preparation which is used for combined therapy of oncological diseases.
US08349900B2 Bupropion hydrobromide polymorphs
Polymorphous and amorphous forms of bupropion hydrobromide are described.
US08349899B1 Selective inhibitors of EG5 motors and methods of use
Embodiments of the present invention comprises a compound of formula I or its enantiomer, diastereomer, stereoisomer or its pharmaceutically acceptable salt, methods of use and methods of synthesis.
US08349898B2 Sigma-1 receptor ligands and methods of use
The invention provides compounds of formula I and compositions thereof. The invention further provides methods of using the compounds and compositions. The compounds of the invention can provide high affinity binding to sigma-1 receptors in a mammal. The compounds can exhibit selectivity for the sigma-1 receptor over the sigma-2 receptor. The compounds and compositions of the invention can also be used to treat conditions that involve the sigma-1 receptor, such as addiction, cardiovascular conditions, and cancer, for example, cancer of the breast, lung, prostate, ovarian, colorectal, or the CNS.
US08349895B2 Products containing highly unsaturated fatty acids for use by women during stages of preconception, pregnancy and lactation/post-partum
A method and product for improving maternal and child health through nutrition. Omega-6 fatty acid and/or omega-3 fatty acid are provided to a woman and/or child prior to, during and/or after pregnancy to improve the health of the woman and her child. The ratios of the omega-6 and omega-3 fatty acids vary during various stages, e.g., pre-pregnancy, pregnancy and post-pregnancy. The omega-6 and omega-3 fatty acids can be in a variety of forms, such as at least one of highly purified algal oil comprising 70% by weight or more of the desired HUFA, triglyceride oil combined with phospholipid, phospholipid, protein and phospholipid combination, or dried marine microalgae.
US08349894B2 Compositions comprising an o/w emulsion containing conjugated linoleic acid
The present invention provides a method of treatment of a human or non-human (e.g. mammalian, avian or reptilian) animal subject by the parenteral administration of a lipophilic pharmaceutical agent, the improvement comprising administering said pharmaceutical agent in an oil-in-water emulsion containing a conjugated linoleic acid or a physiologically tolerable derivative thereof.
US08349889B2 Skin-care preparations containing mupirocin and betamethasone dipropionate
The present invention relates to a topical skin-care preparation in the form of an ointment containing mupirocin and betamethasone dipropionate as active principles and a carrier formulated with all or some of the following components: hydrogenated castor oil, polyethylene glycols and preservatives. The inventive preparation is advantageous over prior art compositions in that it has a specific therapeutic effect on primary and secondary skin infections, such as relief of pruritic inflammatory manifestations of dermatosis, a wide range of activity against the majority of bacterial species involved in skin infections, and a high level of activity against Staphylococcus and Streptococcus, including multi-resistant strains. In addition, the therapeutic effect of the preparation is not affected by the size of the inoculum and the preparation has no sensitization potential, thereby providing the product with an excellent safety profile for use by the patient. Moreover, the preparation can counteract the possible secondary effects of one of the components with the effect of another.
US08349886B2 Nitrogenated 5-membered heterocyclic compound
The purpose of the present invention is to provide a glucokinase activator which is useful as a pharmaceutical agent such as agents for the prophylaxis or treatment of diabetes, obesity and the like, and the like.The present invention is a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.
US08349884B2 Fungicide N-cycloalkyl-N-bicyclimethylene-carboxamide derivatives
The present invention relates N-cycloalkyl-N-bicyclicmethylene-carboxamide, thiocarboxamide or N-substituted carboximidamide derivatives of formula (I) wherein A represents a carbo-linked, 5-membered heterocyclyl group, T represents O or S, Z1 represents a C3-C7-cycloalkyl group, X represents N or a CZ7 and Y1, Y2, Z2, Z3, L1 and L2 represent various substituents, their process of preparation, the preparation of intermediate compounds, their use as fungicide active agents, particularly in the form of fungicide compositions and methods for the control of phytopathogenic fungi, notably of plants, using these compounds or compositions.
US08349883B2 Hydroxamate-based inhibitors of deacetylases B
The present teachings relate to compounds of Formula I: and pharmaceutically acceptable salts, hydrates, esters, and prodrugs thereof, wherein R1, R2, R3, Y, Z, and are as defined herein. The present teachings also provide methods of preparing compounds of Formula I and methods of using compounds of Formula I in treating, inhibiting, or preventing pathologic conditions or disorders mediated wholly or in part by deacetylases.
US08349881B2 Methods for preserving technical products such as fuels and lubricants with a microbicidal composition
Methods for preserving technical products such as fuels and lubricants with a microbicidal composition. The composition is made up of at least one formaldehyde donor compound and at least one antioxidant. The antioxidant is either a gallic ester, a phenol derivative, a L-ascorbic acid, including salts and derivatives thereof, a tocopherol or one of its associated derivatives.
US08349880B2 Bicyclic compounds for the reduction of beta-amyloid production
The present disclosure provides a series of compounds of the formula (I) which reduce β-amyloid peptide (β-AP) production and are useful in the treatment of Alzheimer's Disease and other conditions affected by β-amyloid peptide (β-AP) production.
US08349876B2 Pyridine non-classical cannabinoid compounds and related methods of use
Disclosed are compounds of the formula I: wherein R1, R2, V, W, X, Y and Z can be as defined herein. The compounds can be used in the treatment of disorders mediated by the cannabinoid receptors.
US08349869B2 Macrocylic inhibitors of hepatitis C virus
Inhibitors of HCV replication of formula (I) and the N-oxides, salts, and stereoisomers, wherein each dashed line represents an optional double bond; X is N, CH and where X bears a double bond it is C; R1 is —OR7, —NH—SO2R8; R2 is hydrogen, and where X is C or CH, R2 may also be C1-6alkyl; R3 is hydrogen, C1-6alkyl, C1-6alkoxyC1-6alkyl, C3-7cycloalkyl; R4 is aryl or Het; n is 3, 4, 5, or 6; R5 is halo, C1-6alkyl, hydroxy, C1-6alkoxy, phenyl, or Het; R6 is C1-6alkoxy, or dimethylamino; R7 is hydrogen; aryl; Het; C3-7cycloalkyl optionally substituted with C1-6alkyl; or C1-6alkyl optionally substituted with C3-7cycloalkyl, aryl or with Het; R8 is aryl; Het; C3-7cycloalkyl optionally substituted with C1-6alkyl; or C1-6alkyl optionally substituted with C3-7cycloalkyl, aryl or with Het; aryl is phenyl optionally substituted with one, two or three substituents; Het is a 5 or 6 membered saturated, partially unsaturated or completely unsaturated heterocyclic ring containing 1 to 4 heteroatoms selected from nitrogen, oxygen and sulfur, and being optionally substituted with one, two or three substituents; pharmaceutical compositions containing compounds (I) and processes for preparing compounds (I). Bioavailable combinations of the inhibitors of HCV of formula (I) with ritonavir are also provided.
US08349866B2 High penetration prodrug compositions of 1H-imidazo[4,5-C]quinolin-4-amines and 1H-imidazo[4,5-C]quinolin-4-amine-related compounds
The invention provides compositions of novel high penetration compositions (HPC) or high penetration prodrugs (HPP) of 1H-imidazo[4,5-c]quinolin-4-amines and 1H-imidazo[4,5-c]quinolin-4-amine-related compounds, which are capable of crossing biological barriers with high penetration efficiency. The HPPs are capable of being converted to parent active drugs or drug metabolites after crossing the biological barrier and thus can render treatments for the conditions that the parent drugs or metabolites can. Additionally, the HPPs are capable of reaching areas that parent drugs may not be able to access or to render a sufficient concentration at the target areas and therefore render novel treatments. The HPPs can be administered to a subject through various administration routes, e.g., locally delivered to an action site of a condition with a high concentration or systematically administered to a biological subject and enter the general circulation with a faster rate.
US08349864B2 Pyrano [3,2-C] pyridones and related heterocyclic compounds as pharmaceutical agents for treating disorders responsive to apoptosis, antiproliferation or vascular disruption, and the use thereof
A pharmaceutical composition comprising a pharmaceutically acceptable excipient or carrier and a compound Formula I: or a pharmaceutically acceptable salt or prodrug thereof.
US08349855B2 Polymorphs of erlotinib hydrochloride and method of preparation
The present invention relates to three novel crystalline forms of Erlotinib hydrochloride and method of preparation thereof. Erlotinib hydrochloride is N-(3-ethynylphenyl)-6,7-bis(2-methoxy ethoxy)-4-quinazolinamine hydrochloride of formula-(I). The present invention provides stable novel crystalline forms of Erlotinib hydrochloride designated as Form-M, Form-N and Form-P, and processes for the preparation of the same. Erlotinib hydrochloride can be used as medicament for the treatment of hyperproliferative disorders, such as cancers, in humans.
US08349852B2 Quinazolinone derivatives useful as vanilloid antagonists
There is described a new polymorphic form of 4-(7-Hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl)-benzonitrile and a method of preparing it.
US08349849B2 Heterobicyclic sphingosine 1-phosphate analogs
Compounds of formula (I): that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs that, after phosphorylation, can behave as agonists at S1P receptors.
US08349842B2 Therapeutic agents useful for treating pain
Piperidine Compounds; compositions comprising a Piperidine Compound; and methods for treating or preventing pain, UI, an ulcer, IBD, IBS, an addictive disorder, Parkinson's disease, parkinsonism, anxiety, epilepsy, stroke, a seizure, a pruritic condition, psychosis, a cognitive disorder, a memory deficit, restricted brain function, Huntington's chorea, amyotrophic lateral sclerosis, dementia, retinopathy, a muscle spasm, a migraine, vomiting, dyskinesia, or depression in an animal comprising administering to an animal in need thereof an effective amount of a Piperidine Compound are disclosed. In one embodiment, the Piperidine Compound has the formula: and pharmaceutically acceptable salts thereof, wherein Ar1, Ar2, X, R3, R4, and m are as disclosed herein.
US08349835B2 Aromatic ring fused triazine derivatives and uses thereof
The invention belongs to pharmaceutical field. The invention relates to the compounds according to Formula I, including their optically active forms, pharmaceutically acceptable salts or hydrates, and the pharmaceutical composition comprising thereof as active ingredient; uses in the preparation of vascular endothelial growth factor receptor tyrosine kinase inhibitors, and uses in the preparation of medicament for the treatment and/or prevention of cancer.
US08349834B2 Dioxolane derivates for the treatment of cancer
This invention relates to certain unsaturated fatty acid derivatives of therapeutically active 1,3-dioxolane nucleoside analogues and to pharmaceutical formulations containing them. The said derivatives fall within formula (I). Compounds of formula (I) can be used in the treatment of a cancerous disease, including solid tumors and haematological cancers such as leukaemias, lymphomas and multiple myelomas.
US08349833B2 Compounds, compositions and methods useful for cholesterol mobilisation
The invention relates to classes of pharmaceutically-active heterocyclic compounds and pharmaceutically acceptable salts, and hydrates thereof, and compositions comprising the same. The invention also relates to methods for treating or preventing a disease or disorder, which comprises administering a therapeutically or prophylactically effective amount a compound described herein.
US08349830B2 Aryl aminopyridine PDE10 inhibitors
The present invention is directed to aryl aminopyridine compounds which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.
US08349828B2 Azatricyclic antibiotic compounds
The invention relates to antibacterial compounds of formula I wherein n is 0 or 1; R1 represents H or F; U represents CH2 or, provided n is 1, O or NH; “-----” is a bond or is absent; V represents CH or N when “-----” is a bond, or CH2 or NH when “-----” is absent; W represents CH or N; A represents —(CH2)p—NH—(CH2)q— wherein p is 1 and q is 1 or 2 or, provided U represents CH2 and n is 1, p may also be 0 and q is then 2; G represents one of the groups 1 wherein Z represents N or CH and Q represents O or S; and Z0, Z1 and Z2 each represent CH, or Z0 and Z1 each represent CH and Z2 represents N, or Z0 represents CH, Z1 represents N and Z2 represents CH or N, or Z0 represents N and Z1 and Z2 each represent CH; and to salts of such compounds.
US08349824B2 Triazolopyridine compounds
The invention is concerned with triazolopyridine compounds of formula (I) wherein R1, R2, R3 and R4 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit PDE10A and can be used as pharmaceuticals.
US08349818B2 Method of preventing Type 1 diabetes
The invention relates to novel methods of using 2α-methyl-19-nor-20(S)-1α,25-dihydroxyvitamin D3 or 2-methylene-19-nor-20(S)-1,25-dihydroxyvitamin D3 to prevent Type 1 diabetes in a subject at risk of developing Type 1 diabetes without causing hypercalcemia in the subject.
US08349817B2 Analogues of cilostazol
This invention relates to novel compounds which are derivatives of the phosphodiesterase inhibitor, cilostazol and pharmaceutically acceptable salts thereof. This invention also provides pyrogen-free compositions comprising one or more compounds of the invention and the use of the disclosed compounds and compositions in methods of treating diseases and conditions that are treated by administration of a phosphodiesterase inhibitor, such as cilostazol. The invention also relates to the use of the disclosed compounds and compositions as reagents in analytical studies involving cilostazol.
US08349816B2 Antibacterial treatment of osteoarthritis
The present invention relates to use of an antibacterial agent in the manufacture of a medicament for the treatment of osteoarthritis, more particularly for the treatment of a bacterial infection which is responsible for osteoarthritis. Also described are methods for the diagnosis of osteoarthritis through the detection of certain bacteria in an affected joint of a patient with osteoarthritis.
US08349812B2 Immune stimulatory oligoribonucleotide analogs containing modified oligophosphate moieties
Immunostimulatory oligoribonucleotides (ORN) featuring 5′-triphosphates and various 5′-triphosphate analogs are provided. Also provided are physiologically acceptable salts of the immunostimulatory ORN and pharmaceutical compositions containing the immunostimulatory ORN of the invention. ORN of the invention are useful as adjuvants and can be combined with an antigen to promote an antigen-specific immune response. ORN of the invention are also particularly useful for promoting a Th1-type immune response. Also provided are methods of use of the compounds and pharmaceutical compositions of the invention to enhance an immune response in a subject, as well to treat a number of conditions including cancer, infection, allergy, and asthma, and to vaccinate a subject against an antigen.
US08349811B2 Stable 6-methoxy-2′,3′-dideoxyguanosine, method for preparing the same and pharmaceutical composition containing the same
A stable 6-methoxy-2′,3′-dideoxyguanosine comprises 6-30% water content. It is prepared by absorbing water in 6-methoxy-2′,3′-dideoxyguanosine with less than 6% water content at low temperature and certain humidity, or drying 6-methoxy-2′,3′-dideoxyguanosine with more than 30% water content. The stable 6-methoxy-2′,3′-dideoxyguanosine can be used to prepare medicament composition, and be used to manufacture pharmaceutical for fighting hepatitis B virus or HIV.
US08349810B2 Methods for targeted cleavage and recombination of CCR5
Disclosed herein are methods and compositions for targeted cleavage of a genomic sequence, targeted alteration of a genomic sequence, and targeted recombination between a genomic region and an exogenous polynucleotide homologous to the genomic region. The compositions include fusion proteins comprising a cleavage domain (or cleavage half-domain) and an engineered zinc finger domain, as well as polynucleotides encoding same. Fusion proteins comprising cleavage half-domains are used in pairs to reconstitute a functional cleavage domain. In these fusion proteins, the zinc finger domain can be N-terminal to the cleavage half-domain, or the cleavage half-domain can be N-terminal to the zinc finger domain. The availability of fusion endonucleases having these different polarities allows targeting of zinc finger endonucleases either to opposite strands of the DNA target or to the same strand of the DNA target, thereby increasing the number of possible sequences which can be targeted and cleaved by the fusion proteins.
US08349809B2 Single stranded extended dicer substrate agents and methods for the specific inhibition of gene expression
The invention provides compositions and methods for reducing expression of a target gene in a cell, involving contacting a cell with an isolated double stranded nucleic acid (dsNA) in an amount effective to reduce expression of a target gene in a cell. The dsNAs of the invention possess a single stranded extension (in most embodiments, the single stranded extension comprises at least one modified nucleotide and/or phosphate back bone modification). Such single stranded extended Dicer-substrate siRNAs (DsiRNAs) were demonstrated to be effective RNA inhibitory agents compared to corresponding double stranded DsiRNAs.
US08349805B2 Use of Gonadorelin as a therapeutic agent
The present invention is directed to the use of the peptide compound Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 as a therapeutic agent for the prophylaxis and/or treatment of cancer, autoimmune diseases, fibrotic diseases, inflammatory diseases, neurodegenerative diseases, infectious diseases, lung diseases, heart and vascular diseases and metabolic diseases. Moreover the present invention relates to pharmaceutical compositions preferably in form of a lyophilizate or liquid buffer solution or artificial mother milk formulation or mother milk substitute containing the peptide Pyr-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 optionally together with at least one pharmaceutically acceptable carrier, cryoprotectant, lyoprotectant, excipient and/or diluent.
US08349802B2 Methods and compositions for contributing to the treatment of cancers
Methods and compositions for contributing to the treatment of cancers, especially ovarian tumors, are disclosed. The methods and compositions utilize an endothelin B agonist (ETB) to enhance the delivery and resulting efficacy of chemotherapeutic agent(s) (e.g., cisplatin and/or cyclophosphamide).
US08349801B2 Peptide ligands for G-protein coupled receptors
Disclosed are peptide ligands for G-protein coupled receptors that are useful for treating myocardial and ischemic disorders associated with G-protein coupled receptor activation.
US08349798B2 Caveolin peptides and their use as therapeutics
The present invention relates generally to compositions and methods useful for treating various conditions and afflictions, such as inflammation and cancer. More specifically, the present invention relates to compositions and methods of treatment which utilize peptides comprising at least one caveolin scaffolding domain. Even more specifically, the present invention relates to compositions of fusion peptides comprising the antennapedia homeodomain fused to a caveolin scaffolding domain and to methods of using these peptides to treat various conditions and afflictions.
US08349793B2 Method for treatment of inflammatory disease and disorder
The present disclosure provides a method, composition and kit for treatment of inflammatory disease and disorder using PKC isoform modulators. Exemplary modulators include inhibitors of PKC-alpha, PKC-epsilon and PKC-eta, as well as activators of PKC-delta.
US08349790B2 Substituted octane(ene) nitriles, methods for the synthesis thereof and uses thereof in perfumery
Compounds of general formula (I) below: in which R is a hydrogen atom, a methyl group, a CH2OH group, an ester group, preferably COOEt, or a methylene group, and in which not more than one of the four dashed lines represents a carbon-carbon double bond, and also their enantiomers and their diastereoisomers, a process for preparing them, and their use as an odorant agent in perfuming compositions.
US08349780B2 Compositions and methods incorporating photocatalysts
The present invention relates to a composition including an active material having groups capable of covalent attachment to a substrate in the presence of an acid or a base, a photocatalyst capable of generating an acid or a base upon exposure to light, and a vehicle. The active is a silicone polymer and/or a silicone oligomer, having a molecular weight higher than 1,000 grams/mole, and at least one organic functional group. The compositions may also include surfactants, emulsifiers, oxidants, and other components. A method for treating a substrate is also disclosed. The compositions and methods described herein are useful in personal care product and consumer care product applications.
US08349779B2 Polymers with h-bridge forming functionalities
The invention relates to graft copolymers produced by radically polymerizing polymerisable monomers and, in addition comprising long-chain ethylenically unsaturated compounds which contain alkyl substitutes, in particular acrylates or methacrylates and monomers with hydrogen bridge donator functions. According to said invention, said hydrogen bridge donator monomer is introduced into a polymer backbone and into graft side branches. The inventive polymers are particularly usable for lubricating oil formulations.
US08349776B2 Trunk piston engine lubricating oil compositions
A trunk piston engine lubricating oil composition is disclosed. The trunk piston engine lubricating oil composition includes at least (a) a major amount of a basestock selected from the group consisting of at least one Group III basestock, at least one Group IV basestock and mixtures thereof; (b) at least one detergent additive; and (c) at least one dispersant additive; wherein the concentration of the at least one dispersant additive in the trunk piston engine lubricating oil composition is at least about 0.1 wt. % on an actives basis, based on the total weight of the lubricating oil composition.
US08349774B2 Preparation method of lubricating oil and lubricating oil produced thereby
Provided are a mixed nano-lubricating oil and a method for preparing the same. The method for preparing a mixed nano-lubricating oil includes the steps of: (a) preparing a mixed solution by adding and mixing a nanopowder and a dispersant to a solvent and pulverizing the nanopowder to a primary particle level; (b) modifying the surface of the nanopowder; (c) substituting the solvent of the mixed solution to a lubricating oil; and (d) mixing at least two nano-lubricating oils prepared using physically and chemically different nanopowders. According to the present invention, it is possible to improve the wear resistance and the load resistance at the same time by mixing at least two kinds of lubricating oils having excellent wear resistance or load resistance.
US08349768B2 Use of abscisic acid to alter sensory characteristics of white grapes and wine
This invention describes the use of S-abscisic acid (S-ABA) to modify sensory characteristics such as aroma, bouquet, flavor, mouthfeel, astringency, balance, complexity or finish of white grapes and white wine.
US08349765B2 Mullite-containing carrier for ethylene oxide catalysts
The present invention relates to an improved carrier for an ethylene epoxidation catalyst, the carrier comprising alumina in combination with a stability-enhancing amount of mullite. The invention is also directed to an improved catalyst containing the improved carrier, as well as an improved process for the epoxidation of ethylene using the catalyst of the invention.
US08349762B2 Method for producing catalyst for use in preferential oxidation reaction of carbon monoxide
The present invention provides a method for producing a catalyst for use in preferential carbon monoxide oxidation, which catalyst has a high preferential carbon monoxide oxidation activity and a high methanation activity with respect to the carbon monoxide contained in hydrogen gas, can thus stably reduce the carbon monoxide concentration to an extremely lower level and comprises porous inorganic oxide support particles and, on the basis of the mass thereof, 0.01 to 10 percent by mass of ruthenium and 0.01 to 1 percent by mass of platinum, loaded on the support. The method comprises (1) a step of loading 30 to 70 percent of the total amount of ruthenium to be loaded, on the support particles by a competitive adsorption method and (2) a step of loading the rest of the total amount of ruthenium to be loaded and the total amount of platinum to be loaded, on the ruthenium-loaded support particles produced in step (1) without using a competitive adsorption agent.
US08349760B2 Homogeneous bed of catalyst and a process for transforming hydrocarbons into aromatic compounds using said bed
The invention concerns a homogeneous bed of particles of a catalyst, said catalyst comprising at least one amorphous matrix, at least one noble metal, at least one additional metal M and at least one halogen, and in which, for a catalyst particle, CPt is the local concentration of noble metal Pt; CM is the local concentration of additional metal M; CX is the local concentration of halogen; said catalyst being in the form of a homogeneous bed of particles, in which across the diameter of the particle, at least 70% of the values CPt/CM or CPt/CX differ from the mean local ratio by at most 30%, and in which the mole ratio M/Pt in the catalyst is in the range 1.8 to 6.
US08349757B2 Photocatalytic electrode and fuel cell
The invention provides an electrode comprising an electrically conductive material having a surface capable of producing surface enhanced Raman scattering of incident light from a complex adsorbed at the surface of the electrode, the complex including the electrically conductive material combined with a second material that is substantially reducible and not substantially oxidizable. The surface of the electrode can be microroughened. The invention also includes a method for making various embodiments of the electrode, and a method of generating electricity using the electrode. In accordance with a further aspect of the invention, a fuel cell is provided including the electrode of the invention.
US08349755B2 Zeolite-based honeycomb body
Zeolite-based honeycomb bodies and methods of manufacturing same. Zeolite-based honeycomb bodies especially suited for engine exhaust treatment applications include a primary phase comprising a zeolite having a SiO2 to Al2O3 molar ratio in the range from 5 to 300. The zeolite-based composites are porous with an open porosity of at least 25% and a median pore diameter of at least 1 micron. The zeolite-based honeycomb bodies can be manufactured by an extrusion method.
US08349751B2 Glass composition for substrates
A glass composition for substrates having good polishability while securing characteristics for FPD substrates, especially for PDP substrates, from which a glass substrate having excellent polishing workability and productivity can be obtained, is provided.A glass composition for substrates, which is characterized by comprising, as represented by mass % based on oxides, from 55 to 75% of SiO2, from 5 to 15% of Al2O3, from 0 to 4% of MgO, more than 5.5% and at most 12% of CaO, from 5 to 18% of SrO, from 0 to 13% of BaO, from 0.5 to 6% of ZrO2, from 0 to 10% of Na2O, from 0 to 15% of K2O, from 6 to 20% of Na2O+K2O, from 17 to 25% of MgO+CaO+SrO+BaO, and from 15 to 25% of CaO+SrO, as a glass matrix composition; and having a glass transition point of at least 600° C., an average thermal expansion coefficient of from 75×10−7 to 90×10−7/° C. within a range of from 50 to 350° C., and an abrasion resistance of at least 98.
US08349745B2 Fabrication of a semiconductor nanoparticle embedded insulating film luminescence device
A method is provided for fabricating a semiconductor nanoparticle embedded Si insulating film for short wavelength luminescence applications. The method provides a bottom electrode, and deposits a semiconductor nanoparticle embedded Si insulating film, including the element of N, O, or C, overlying the bottom electrode. After annealing, a semiconductor nanoparticle embedded Si insulating film has a peak photoluminescence (PL) at a wavelength in the range of 475 to 750 nanometers.
US08349744B2 Double deposition of a stress-inducing layer in an interlayer dielectric with intermediate stress relaxation in a semiconductor device
Enhanced efficiency of a stress relaxation implantation process may be achieved by depositing a first layer of reduced thickness and relaxing the same at certain device regions, thereby obtaining an enhanced amount of substantially relaxed dielectric material in close proximity to the transistor under consideration, wherein a desired high amount of stressed dielectric material may be obtained above other transistors by performing a further deposition process. Hence, the negative effect of the highly stressed dielectric material for specific transistors, for instance in densely packed device regions, may be significantly reduced by depositing the highly stressed dielectric material in two steps with an intermediate relaxation implantation process.
US08349743B2 Method for fabricating light emitting device
Disclosed is a method for fabricating a light emitting device. The method includes forming an oxide including gallium aluminum over a gallium oxide substrate, forming a nitride including gallium aluminum over the oxide including gallium aluminum and forming a light emitting structure over the nitride including gallium aluminum.
US08349739B2 Conformal etch material and process
The present disclosure provides a method for etching a substrate. The method includes forming a resist pattern on the substrate; applying an etching chemical fluid to the substrate, wherein the etching chemical fluid includes a diffusion control material; removing the etching chemical fluid; and removing the resist pattern.
US08349738B2 Metal precursors for deposition of metal-containing films
Compositions and methods for forming a metal-containing thin film on a substrate. A reactor and at least one substrate in the reactor are provided. A metal-containing bis-β-diketiminate precursor is introduced into the reactor. The reactor is maintained at a set temperature and pressure, and the precursor is contacted with the substrate to form a metal-containing film on the substrate.
US08349737B2 Manufacturing method of array substrate using lift-off method
A method of forming a pattern includes forming a photoresist pattern on a substrate, forming a first material layer on substantially an entire surface of the substrate including the photoresist pattern, heat-treating the substrate including the first material layer and the photoresist pattern, and forming the pattern by removing the photoresist pattern and the portion of the first material layer on the photoresist pattern. A method of manufacturing an array substrate includes forming a pixel region bounded by gate and data lines, and a thin film transistor; an insulating layer is selectively removed to form a passivation layer using a photoresist pattern as an etching mask; a transparent conductive layer is formed on substantially the entire substrate, and the substrate is heat treated. The photoresist pattern and the portion of the transparent conductive layer on the photoresist pattern are removed by a stripping material.
US08349736B2 Semiconductor device manufacturing method and semiconductor device
A base conductive member is formed on a surface and in a hole section of a substrate, and a resist is formed on a part of the base conductive member in which a conductive layer is not to be formed. The conductive layer is formed on a part except for the part in which the resist has been formed, and a mask metal is formed on the conductive layer. Then, the resist is removed, and the base conductive member is etched using the mask metal as a mask to form the conductive layer into a predetermined shape.
US08349732B2 Implanted metal silicide for semiconductor device
A device and a method for forming a metal silicide is presented. A device, which includes a gate region, a source region, and a drain region, is formed on a substrate. A metal is disposed on the substrate, followed by a first anneal, forming a metal silicide on at least one of the gate region, the source region, and the drain region. The unreacted metal is removed from the substrate. The metal silicide is implanted with atoms. The implant is followed by a super anneal of the substrate.
US08349726B2 Method for fabricating a structure for a semiconductor device using a halogen based precursor
There is described a method of fabricating a dual damascene structure for a semiconductor device. A halogen based pre-cursor is used during vapor deposition of a diffusion barrier layer in a trench or via formed in a substrate. Residual halogen from the deposition is allowed to remain on the barrier layer and is used to catalyse growth of a metal layer on the barrier layer to fill the trench or via.
US08349722B2 Silicon oxycarbide, growth method of silicon oxycarbide layer, semiconductor device and manufacture method for semiconductor device
A method of manufacturing a semiconductor device includes the steps of: preparing an underlying structure having a silicon carbide layer covering a copper wiring, and growing silicon oxycarbide on the underlying structure by vapor deposition using, as source gas, tetramethylcyclotetrasiloxane, carbon dioxide gas and oxygen gas, a flow rate of said oxygen gas being at most 3% of a flow rate of the carbon dioxide gas. The surface of the silicon carbide layer of the underlying structure may be treated with a plasma of weak oxidizing gas which contains oxygen and has a molecular weight larger than that of O2 to bring the surface more hydrophilic. Film peel-off and cracks in the interlayer insulating layer decrease.
US08349720B2 Nonvolatile semiconductor memory and manufacturing method thereof
A nonvolatile semiconductor memory includes a memory cell string having a plurality of memory cell transistors connected in series, a selection gate transistor connected in series with one end of the memory cell string, and having a gate electrode provided on a gate insulating film on a semiconductor substrate, and an element isolation insulating layer which is provided in the semiconductor substrate. The gate electrode includes a first gate electrode provided on the gate insulating film, a first and second insulating films provided on the first gate electrode, and a second gate electrode provided on the second insulating film and the element isolation insulating layer, and electrically connected to the first gate electrode. An first upper surface portion of the element isolation insulating layer below the second gate electrode is leveled with an upper surface of the first gate electrode.
US08349719B2 Semiconductor device and method for fabricating the same
A semiconductor device and a method for fabricating the same. A plurality of gate patterns are formed over a first-conductivity type silicon layer of a silicon-on-insulator semiconductor substrate including a buried insulation layer, so as to be separated from each other. A plurality of silicon bodies are formed under the gate patterns, by removing a portion of the first-conductivity type silicon layer exposed between the gate patterns. A plurality of polysilicon spacers are formed over a sidewall of the silicon bodies, and each contains a second-conductivity type dopant. A contact plug is electrically connected to at least one of the polysilicon spacers.
US08349718B2 Self-aligned silicide formation on source/drain through contact via
According to certain embodiments, a silicide layer is formed after the fabrication of a functional gate electrode using a gate-last scheme. An initial semiconductor structure has at least one impurity regions formed on a semiconductor substrate, a sacrifice film formed over the impurity region, an isolation layer formed over the sacrifice film and a dielectric layer formed over the isolation film. A via is patterned into the dielectric layer of the initial semiconductor structure and through the thickness of the isolation layer such that a contact opening is formed in the isolation layer. The sacrifice film underlying the isolation layer is then removed leaving a void space underlying the isolation layer. Then, a metal silicide precursor is placed within the void space, and the metal silicide precursor is converted to a silicide layer through an annealing process.
US08349717B2 High voltage LDMOS
A semiconductor device, such as a LDMOS device, comprising: a semiconductor substrate; a drain region in the semiconductor substrate; a source region in the semiconductor substrate laterally spaced from the drain region; and a drift region in the semiconductor substrate between the drain region and the source region. A gate is operatively coupled to the source region and is located offset from the drain region on a side of the source region opposite from the drain region. When the device is in an on state, current tends to flow deeper into the drift region to the offset gate, rather than near the device surface. The drift region preferably includes at least first and second stacked JFETs. The first and second stacked JFETs include first, second and third layers of a first conductivity type, a fourth layer intermediate the first and second layers including alternating pillars of the first conductivity type and of a second conductivity type extending between the source and drain regions; and a fifth layer intermediate the second and third layers, including alternating pillars of the first and second conductivity types extending between the source and drain regions.
US08349701B2 Combination of a substrate and a wafer
The invention pertains to a combination of a substrate (6) and a wafer (15), wherein the substrate (6) and the wafer (15) are arranged parallel to one another and bonded together with the aid of an adhesive layer (8) situated between the substrate (6) and the wafer (15), and wherein the adhesive is chosen such that its adhesive properties are neutralized or at least diminished when a predetermined temperature is exceeded. According to the invention, the adhesive layer (8) is only applied annularly between the substrate (6) and the wafer (15) in the edge region of the wafer (15).
US08349699B2 Methods of forming trench isolation in the fabrication of integrated circuitry and methods of fabricating integrated circuitry
First and second isolation trenches are formed into semiconductive material of a semiconductor substrate. The first isolation trench has a narrowest outermost cross sectional dimension which is less than that of the second isolation trench. An insulative layer is deposited to within the first and second isolation trenches effective to fill remaining volume of the first isolation trench within the semiconductive material but not that of the second isolation trench within the semiconductive material. The insulative layer comprises silicon dioxide deposited from flowing TEOS to the first and second isolation trenches. A spin-on-dielectric is deposited over the silicon dioxide deposited from flowing the TEOS within the second isolation trench within the semiconductive material, but not within the first isolation trench within the semiconductive material. The spin-on-dielectric is deposited effective to fill remaining volume of the second isolation trench within the semiconductive material. The spin-on-dielectric is densified within the second isolation trench.
US08349697B2 Field effect transistor with air gap dielectric
A field effect transistor (FET) that includes a drain formed in a first plane, a source formed in the first plane, a channel formed in the first plane and between the drain and the source and a gate formed in the first plane. The gate is separated from at least a portion of the body by an air gap. The air gap is also in the first plane.
US08349692B2 Channel surface technique for fabrication of FinFET devices
A FinFET (p-channel) device is formed having a fin structure with sloped or angled sidewalls (e.g., a pyramidal or trapezoidal shaped cross-section shape). When using conventional semiconductor substrates having a (100) surface orientation, the fin structure is formed in a way (groove etching) which results in sloped or angled sidewalls having a (111) surface orientation. This characteristic substantially increases hole mobility as compared to conventional fin structures having vertical sidewalls.
US08349689B2 Non-volatile memory device and method for fabricating the same
A non-volatile memory device includes a pair of columnar cell channels vertically extending from a substrate, a doped pipe channel arranged to couple lower ends of the pair of columnar cell channels, insulation layers over the substrate in which the doped pipe channel is buried, memory layers arranged to surround side surfaces of the columnar cell channels, and control gate electrodes arranged to surround the memory layers.
US08349687B2 Transistor gate forming methods and transistor structures
A transistor gate forming method includes forming a metal layer within a line opening and forming a fill layer within the opening over the metal layer. The fill layer is substantially selectively etchable with respect to the metal layer. A transistor structure includes a line opening, a dielectric layer within the opening, a metal layer over the dielectric layer within the opening, and a fill layer over the metal layer within the opening. The metal layer/fill layer combination exhibits less intrinsic less than would otherwise exist if the fill layer were replaced by an increased thickness of the metal layer. The inventions apply at least to 3-D transistor structures.
US08349682B2 Method for fabricating metal gate transistor and polysilicon resistor
An integrated method includes fabricating a metal gate transistor and a polysilicon resistor structure. A photoresistor layer is defined by an SAB photo mask and covers a part of a high resistance structure of the polysilicon resistor. When the dummy gate of the transistor is etched, the part of the high resistance structure is protected by the patterned photoresistor layer. The polysilicon resistor is formed simultaneously with the transistor. Furthermore, the polysilicon resistor still has sufficient resistance and includes two metal structures for electrical connection.
US08349680B2 High-k metal gate CMOS patterning method
The present disclosure provides a method of fabricating a semiconductor device. The method includes providing a semiconductor substrate having a first active region and a second active region, forming a high-k dielectric layer over the semiconductor substrate, forming a capping layer over the high-k dielectric layer, forming a first metal layer over the capping layer, the first metal layer having a first work function, forming a mask layer over the first metal layer in the first active region, removing the first metal layer and at least a portion of the capping layer in the second active region using the mask layer, and forming a second metal layer over the partially removed capping layer in the second active region, the second metal layer having a second work function.
US08349678B2 Laterally diffused metal oxide semiconductor transistor with partially unsilicided source/drain
A method of fabricating a laterally diffused metal oxide semiconductor (LDMOS) transistor includes forming a dummy gate over a substrate. A source and a drain are formed over the substrate on opposite sides of the dummy gate. A first silicide is formed on the source. A second silicide is formed on the drain so that an unsilicided region of at least one of the drain or the source is adjacent to the dummy gate. The unsilicided region of the drain provides a resistive region capable of sustaining a voltage load suitable for a high voltage LDMOS application. A replacement gate process is performed on the dummy gate to form a gate.
US08349676B2 Electrostatic discharge management apparatus, systems, and methods
Apparatus, systems, and methods may include managing electrostatic discharge events by using a semiconductor device having a non-aligned gate to implement a snap-back voltage protection mechanism. Such devices may be formed by doping a semiconductor substrate to form a first conductive region as a well, forming one of a source region and a drain region in the well, depositing a layer of polysilicon on the substrate to establish a gating area that does not overlap the one of the source region and the drain region, and forming an integrated circuit supported by the substrate to couple to the one of the source region and the drain region to provide snap-back voltage operation at a node between the integrated circuit and the source or drain region. Additional apparatus, systems, and methods are disclosed.
US08349669B2 Thin film transistors using multiple active channel layers
Embodiments disclosed herein generally relate to TFTs and methods of fabricating the TFTs. In TFTs, the active channel carries the current between the source and drain electrodes. By tailoring the composition of the active channel, the current can be controlled. The active channel may be divided into three layers, a gate control layer, a bulk layer, and an interface control layer. The separate layers may have different compositions. Each of the gate control, bulk and interface control layers may additionally comprise multiple layers that may have different compositions. The composition of the various layers of the active channel comprise oxygen, nitrogen, and one or more elements selected from the group consisting of zinc, indium, cadmium, tin, gallium and combinations thereof. By varying the composition among the layers, the mobility, carrier concentration and conductivity of the various layers may be controlled to produce a TFT having desired properties.
US08349666B1 Fused buss for plating features on a semiconductor die
A method for forming a semiconductor structure includes forming a plurality of fuses over a semiconductor substrate; forming a plurality of interconnect layers over the semiconductor substrate and a plurality of interconnect pads at a top surface of the plurality of interconnect layers; and forming a seal ring, wherein the seal ring surrounds active circuitry formed in and on the semiconductor substrate, the plurality of interconnect pads, and the plurality of fuses, wherein each fuse of the plurality of fuses is electrically connected to a corresponding interconnect pad of the plurality of interconnect pads and the seal ring, and wherein when each fuse of the plurality of fuses is in a conductive state, the fuse electrically connects the corresponding interconnect pad to the seal ring.
US08349662B2 Integrated circuit having memory cell array, and method of manufacturing same
An integrated circuit device (e.g., a logic device or a memory device) having (i) a memory cell array which includes a plurality of memory cells (for example, memory cells having electrically floating body transistors) arranged in a matrix of rows and columns, wherein each memory cell includes at least one transistor having a gate, gate dielectric and first, second and body regions, wherein: (i) the gate and gate dielectric are disposed on or above the first semiconductor layer that is disposed on or above an insulating layer or region, (ii) the body region of each transistor is electrically floating, (iii) the transistors of adjacent memory cells include a layout that provides a common first region, and (iv) the first regions of the transistors are comprised of a semiconductor material which is different from the material of the first semiconductor layer. Also disclosed are inventive methods of manufacturing, for example, such integrated circuit devices.
US08349659B1 Integrated shield for a no-lead semiconductor device package
The present invention integrates a shield on a flat, no-lead (FN) semiconductor package, which has multiple rows of contact pads along any side. The FN semiconductor package will have at least one inner row and one outer row of contact pads on at least one side. The inner and outer rows of contact pads and a die attach pad form the foundation for the FN semiconductor package. A die is mounted on the die attach pad and connected by wirebonds to certain contact pads of the inner rows of contact pads. An overmold body is formed over the die, die attach pad, wirebonds, and inner row of contact pads, and substantially encompasses each contact pad of the outer row of contact pads. A conformal coating is applied over the overmold body, including the exposed surfaces of the contact pads of the outer row of contact pads, providing a shield.
US08349655B2 Method of fabricating a two-sided die in a four-sided leadframe based package
A method of fabricating a leadframe-based semiconductor package, and a semiconductor package formed thereby, are disclosed. In embodiments, a semiconductor die having die bond pads along two adjacent edges may be electrically coupled to four sides of a four-sided leadframe. Embodiments relate to lead and no-lead type leadframe.
US08349651B2 Stacked package and method of manufacturing the same
In one embodiment, the stacked package includes a first chip disposed over a package substrate. The first chip has at least one first chip dummy pad, and the first chip dummy pad is not electrically connected to circuits of the first chip. A first dummy bonding wire is connected to the first chip dummy pad and the package substrate. A second chip is disposed over at least a portion of the first chip, and the second chip has at least one second chip bonding pad. A first bonding wire is electrically connected to the second chip bonding pad and the first dummy bonding wire.
US08349650B1 Multi-layered integrated circuit and apparatus with thermal management and method
A multi-layered semiconductor apparatus capable of producing at least 500 W of continuous power includes at least two device substrates arranged in a stack. Each of the at least two device substrates has a first side and a second side opposite to the first side, and each of the at least two device substrates is configured to produce an average power density higher than 100 W/cm2. A plurality of active devices are provided on the first side of each of the at least two device substrates. The plurality of active devices are radiatively coupled among the at least two device substrates. At least one of the at least two device substrates is structured to provide a plurality of cavities on its second side to receive corresponding ones of the plurality of active devices on the first side of an adjacent one of the at least two device substrates.
US08349645B2 Mask and film formation method using the same
A mask includes: a tabular first section which includes a side portion and an opening portion formed at a position corresponding to a film formation region of a substrate and on which the substrate is to be disposed so that the first section overlaps a face of the substrate on which a film is to be formed; and a second section which is provided along the side portion of the first section, and covers at least one of portions of a side face of the substrate, wherein second sections of two adjacent masks overlap each other and a superposed section is thereby formed when a plurality of masks are arrayed in a lateral direction thereof.
US08349643B2 Photovoltaic device and manufacturing method thereof
A photovoltaic device capable of improving an output characteristic is provided. The photovoltaic device includes an n-type single-crystal silicon substrate, a p-type amorphous silicon substrate, and a substantially intrinsic i-type amorphous silicon layer disposed between the n-type single-crystal silicon substrate and the p-type amorphous silicon layer. The i-type amorphous silicon layer includes: a first section which is located on the n-type single-crystal silicon substrate side, and which has an oxygen concentration equal to or below 1020 cm−3; and a second section which is located on the p-type amorphous silicon layer side, and which has an oxygen concentration equal to or above 1020 cm−3.
US08349642B2 Method for treating a metal oxide layer
The invention relates to a method for treating a metal oxide layer deposited on a substrate. The method comprises the step of applying a substantially atmospheric plasma process at a relatively low temperature. Preferably, the temperature during the plasma process is lower than approximately 180° C. Further, the atmospheric plasma process can be applied in a plasma chamber comprising H2 gas and He gas.
US08349630B1 Methods for manufacturing thin film transistor array substrate and display panel
The present invention provides methods for manufacturing a thin film transistor (TFT) array substrate and a display panel. The method for manufacturing the TFT array substrate comprises the following steps: forming a plurality of gate electrodes, a gate insulating layer, a semiconductor layer, an ohmic contact layer, an electrode layer and a photo-resist layer on a transparent substrate in sequence; using a multi tone mask to pattern the photo-resist layer; forming a plurality of source electrodes and a plurality of drain electrodes at both sides of the channels, respectively; heating the photo-resist layer; etching the semiconductor layer; removing the photo-resist layer; forming a passivation layer on the channels, the source electrodes and the drain electrodes; and forming a pixel electrode layer on the passivation layer. The present invention can reduce an amount of the required masks in the fabrication process, and only one wet etching is required to etch the metal material on the TFT array substrate.
US08349629B2 Semiconductor light-emitting element and method of manufacturing same
A semiconductor light-emitting element includes a first semiconductor layer having a first conduction type, a second semiconductor layer having a second conduction type, an active layer provided between the first and second semiconductor layers, a polarity inversion layer provided on the second semiconductor layer, and a third semiconductor layer having the second conduction type provided on the polarity inversion layer. Crystal orientations of the first through third semiconductor layers are inverted, with the polarity inversion layer serving as a boundary. The first and third semiconductor layers have uppermost surfaces made from polar faces having common constitutional elements. Hexagonal conical protrusions arising from a crystal structure are formed at outermost surfaces of the first and third semiconductor layers. The first through third semiconductor layers are made from a wurtzite-structure group III nitride semiconductor, and are layered along a C-axis direction of the crystal structure.
US08349628B2 Methods of fabricating light emitting diode devices
An embodiment of the disclosure includes a method of fabricating a plurality of light emitting diode devices. A plurality of LED dies is provided. The LED dies are bonded to a carrier substrate. A patterned mask layer comprising a plurality of openings is formed on the carrier substrate. Each one of the plurality of LED dies is exposed through one of the plurality of the openings respectively. Each of the plurality of openings is filled with a phosphor. The phosphor is cured. The phosphor and the patterned mask layer are polished to thin the phosphor covering each of the plurality of LED dies. The patterned mask layer is removed after polishing the phosphor.
US08349627B2 Method for fabricating a light emitting diode package structure
The present invention discloses a method for fabricating a light emitting diode (LED) package structure. The method comprises the following steps: a carrier having a substrate and a first protrusion is provided, wherein the first protrusion is disposed on the substrate and has a recess. An adhesion layer and a LED chip are disposed on a bottom of the recess, wherein the adhesion layer is bonded between the carrier and the LED chip, and a ratio between a width of the recess and a width of the LED chip is larger than 1 and smaller than or equal to 1.5 such that a gap existing between a sidewall of the LED chip and an inner sidewall of the recess.
US08349623B2 Method and apparatus for manufacturing thin film photoelectric conversion module
A method for manufacturing a thin film photoelectric conversion module comprising the steps of: (A) forming a plurality of divided strings by dividing a string, in which thin film photoelectric conversion elements provided by sequentially laminating a first electrode layer, a photoelectric conversion layer and a second electrode layer on the surface of an insulating substrate are electrically connected in series, into a plurality of strings by dividing grooves, electrically insulating and separating the first electrode layer and the second electrode layer one from the other and extending in a serial connection direction; and (B) performing reverse biasing by applying a reverse bias voltage to each of thin film photoelectric conversion elements of the divided string.
US08349621B2 Ligand molecule-immobilized polymer, ligand molecule-immobilized particle, method of detecting target substance, and method of separating target substance
A ligand molecule-immobilized polymer has a structure represented by the following general formula (1). In the general formula (1), R1 represents a ligand molecule-containing group, R2 represents a hydrophobic group, R3 represents a spacer site, R4 represents a hydrophilic group, R5 represents a group having charge, a to d specify a composition ratio and each represent an integer of 1 or more, and n and m specify chain lengths and represent integers satisfying the relationships of 1≦n(a+b+c+d)≦10,000 and 1≦m≦350.
US08349618B2 Diagnostic devices
The present invention relates to analytical methods, platforms, and devices for the rapid and efficient immunochromatic determination of one or more components in fluid samples.
US08349617B2 Optical sensor comprising diffraction gratings with functionalized pores and method of detecting analytes using the sensor
Diffraction gratings comprising a substrate with protrusions extending therefrom. In one embodiment, the protrusions are made of a porous material, for example porous silicon with a porosity of greater than about 10%. The diffraction grating may also be constructed from multiple layers of porous material, for example porous silicon with a porosity of greater than about 10%, with protrusion of attached thereto. In some embodiments the protrusions may be made from photoresist or another polymeric material. The gratings are the basis for sensitive sensors. In some embodiments, the sensors are functionalized with selective binding species, to produce sensors that specifically bind to target molecules, for example chemical or biological species of interest.
US08349616B2 Assays
A method for assaying a sample for each of multiple analysis is described. The method includes contacting an array of spaced-apart test zones with a liquid sample (e.g., whole blood). The test zones are disposed within a channel of a microfluidic device. The channel is defined by at least one flexible wall and a second wall which may or may not be flexible. Each test zone includes a probe compound specific for a respective target analyte. The microfluidic device is compressed to reduce the thickness of the channel, which is the distance between the inner surfaces of the walls within the channel. The presence of each analyte is determined by optically detecting an interaction at each of multiple zones for which the distance between the inner surfaces at the corresponding location is reduced. The interaction at each test zone is indicative of the presence in the sample of a target analyte.
US08349613B2 Mass spectroscopy techniques for detecting vitamin D compounds in a sample
Methods for determining the amount of vitamin D compounds in a sample are provided. The methods can employ LC-MS/MS techniques and optionally the use of deuterated internal standards. Methods for diagnosing vitamin D deficiencies are also provided.
US08349610B2 Methods, systems and devices for analyzing a surfactant-treated biological fluid sample
Devices, methods and systems effective to evaluate a physical or chemical property of a surfactant-treated biological fluid sample are provided.
US08349608B2 Method for production of tooth, and tooth produced by the method
Disclosed is a method for producing a tooth, which comprises the steps of: positioning a first cell mass substantially comprising either one of amniotic mesenchymal cells or epithelial cells, and a second cell mass substantially comprising the other one in the inside of a support carrier while keeping them in close contact with each other without being mixed together; and culturing the first and second cell masses in the inside of the support carrier.
US08349606B2 Lentiviral vectors for the preparation of immunotherapeutical compositions
The invention relates to an immunogenic composition comprising a recombinant vector characterized in that it comprises a polynucleotide comprising the cis-acting central initiation region (cPPT) and the cis-acting termination region (CTS), these regions being of retroviral or retroviral-like origin, said vector comprising in addition a defined nucleotide sequence (transgene or sequence of interest) and regulatory signals of retrotranscription, expression and encapsidation of retroviral or retroviral-like origin, wherein the composition is capable of inducing or of stimulating a cell-mediated response for instance a CTL (Cytotoxic T Lymphocytes) response or a CD4 response, against one or several epitopes encoded by the transgene sequence present in the vector.
US08349600B2 Polypeptides having nucleic acid binding activity
Polypeptides having nucleic acid binding activity are provided. Methods of stabilizing a nucleic acid duplex are provided. Methods of promoting the annealing of complementary nucleic acid strands are provided. Methods of increasing the processivity of a DNA polymerase are provided. Methods of enhancing the activity of a nucleic acid modification enzyme are provided. Fusion proteins are provided. Methods of using fusion proteins are provided. Kits are provided.
US08349596B2 Method for the enzymatic production of 2-hydroxy-2-methyl carboxylic acids
Provided is a composition containing: an isolated and purified polypeptide containing the amino acid sequence of SEQ ID NO: 4; and/or a heterodimeric enzyme containing: the isolated and purified polypeptide containing the amino acid sequence of SEQ ID NO: 4; and an isolated and purified polypeptide containing the amino acid sequence of SEQ ID NO: 2. Also provided is a process for producing a 2-hydroxy-2-methyl carboxylic acid or a salt or ester thereof, wherein the process involves: contacting a 3-hydroxy carboxylic acid or a salt or ester thereof with the above-mentioned composition to produce the 2-hydroxy-2-methyl carboxylic acid or the salt or ester thereof.
US08349595B2 Method for increasing the content of docosahexaenoic acid in fat-containing materials or in fats and oils
[PROBLEMS] To provide a fat-and-oil in which the content of docosahexaenoic acid is increased.[MEANS FOR SOLVING PROBLEMS] A process for producing highly unsaturated fatty acids comprising culturing a stramenopile capable of producing highly unsaturated fatty acids in a culture medium containing an inhibitor for fatty acid desaturases; fats-and-oils in which the content of highly unsaturated fatty acids, particularly docosahexaenoic acid produced by the relevant method, is increased. A method for enhancing the productivity of highly unsaturated fatty acids in stramenopiles, comprising culturing a stramenopile in a culture medium containing an inhibitor for fatty acid desaturases; stramenopiles having the enhanced productivity of highly unsaturated fatty acids, generated by the relevant method. Particularly, the process for producing highly unsaturated fatty acids, the method for enhancing the productivity of highly unsaturated fatty acids, and the stramenopile having the enhanced productivity of highly unsaturated fatty acids, wherein the stramenopile is a microorganism classified into Labyrinthulea.
US08349592B2 Producing fermentation products in the presence of aldehyde dehydrogenase
The invention relates to a process of fermenting plant material in a fermentation medium into a fermentation product using a fermenting organism, wherein one or more aldehyde dehydrogenases are present in the fermentation medium.
US08349587B2 Methods and systems for chemoautotrophic production of organic compounds
The present disclosure identifies pathways, mechanisms, systems and methods to confer chemoautotrophic production of carbon-based products of interest, such as sugars, alcohols, chemicals, amino acids, polymers, fatty acids and their derivatives, hydrocarbons, isoprenoids, and intermediates thereof, in organisms such that these organisms efficiently convert inorganic carbon to organic carbon-based products of interest using inorganic energy, such as formate, and in particular the use of organisms for the commercial production of various carbon-based products of interest.
US08349586B1 Commensal strain of E. coli encoding an HIV GP41 protein
The present invention relates, e.g., to a commensal bacterium which can colonize the genitourinary and/or gastrointestinal mucosa, and which, under suitable conditions, secretes a heterologous antimicrobial polypeptide, wherein the secreted antimicrobial polypeptide is effective to inhibit infectivity by, or a pathogenic activity of, a pathogen. In a most preferred embodiment, the antimicrobial polypeptide inhibits HIV infection (e.g., fusion) and/or pathogenesis. Also described are preventive or therapeutic compositions comprising the commensal bacteria, and methods to inhibit infectivity and/or pathogenesis, using the bacteria.
US08349583B2 Distinguishing cells in a sample by inactivating extracellular enzyme before releasing intracellular enzyme
A method for detecting the absence or presence of cells of interest in a liquid sample is provided. The method comprises providing a sample suspected of containing cells of interest that contain an intracellular enzyme with a measurable activity. The sample further comprises an extracellular medium that also includes an extracellular enzyme with the measurable activity. The method further comprises the steps of treating the liquid sample with a reagent that inactivates the measurable activity in the extracellular medium but does not inactivate the measurable activity in the cells of interest, lysing the cells of interest to release the intracellular enzyme, and measuring the measurable activity. Thus, the measurable activity of the intracellular enzyme can be measured without interference from the extracellular enzyme. The invention is particularly useful for treatment of bacterially-infected blood using a detection assay based on adenylate kinase activity.
US08349582B2 High-efficiency viable sampler for ultrafine bioaerosols
Exemplary embodiments provide bioaerosol detection systems and methods for detecting bioaerosols. In one embodiment, the bioaerosol detection system can include a humidifier to increase the humidity of a continuously flowing sample volume of a bioaerosol sample using a biologically compatible liquid medium, and an amplifier to deposit vapor on the bioaerosol sample for a particle size amplification process. Bioaerosol(s) can thus be detected and sampled while simultaneously maintaining their viability. The disclosed bioaerosol detection systems and the methods can provide high efficiency for sampling and detecting ultrafine bioaerosol(s) such as viruses and proteins, which can be smaller than 0.3 μm in diameter and can be as small as 20 nm.
US08349576B2 eEF2K assays for identifying compounds that inhibit eEF2K activity
Assays for identifying novel compounds for inhibiting eEF2 kinase and consequence peptides employed therein.
US08349567B2 Cathepsin C-based screening methods for identifying modulators of pain
Present invention concerns the use of Cathepsin C. Other aspects of the invention concern methods for screening pharmaceuticals, for diagnosing pain susceptibility and for the treatment of pain.
US08349564B2 Method for continuous mode processing of the contents of multiple reaction receptacles in a real-time amplification assay
An automated analyzer for performing multiple diagnostic assays simultaneously includes multiple stations in which discrete aspects of the assay are performed on fluid samples contained in sample vessels. The analyzer includes stations for automatically preparing a sample, incubating the sample, preforming an analyte isolation procedure, ascertaining the presence of a target analyte, and analyzing the amount of a target analyte. An automated receptacle transporting system moves the sample vessels from one station to the next. A method for performing an automated diagnostic assay includes an automated process for isolating and amplifying a target analyte, and, in one embodiment, a method for real-time monitoring of the amplification process.
US08349560B2 Method for diagnosing acute lymphomic leukemia (ALL) using miR-222
Disclosed are compositions and methods for reducing the proliferation of ALL cancer cells through targeted interactions with ALL1 fusion proteins.
US08349558B2 Detection of individual T-cell reaction patterns against tumor-associated antigens (TAA) in tumor patients as a basis for the individual therapeutic vaccination of patients
The present invention relates to a method for identifying the preferential target antigens of antitumoural T-cells of a tumour patient, comprising: a) providing T-cells from the blood of at least one tumour patient, b) providing dendritic cell (DCs) and/or B-lymphocytes (BLCs) that are autologous for said tumour patient, wherein said DCs and BLCs were transfected beforehand with a selection of mRNAs encoding for T-cell-immunogenic tumour-associated antigens (TAA), and express these, c) contacting said T-cells with the DCs and/or BLCs, d) identifying of those T-cells that recognize antigens of the DCs and/or BLCs, and e) identifying of the preferential target antigens of antitumoural T-cells of the at least one tumour patient on the basis of the T-cells that recognize antigens of the DCs and/or BLCs. The method can furthermore comprise the expansion of the T-cells that recognize the antigens of the DCs and/or BLCs. The present invention furthermore relates to a method for producing an individualized tumour vaccine or individualized tumour therapeutic, as well as corresponding methods for treating a tumourous disease using the individualised tumour vaccine or individualised tumour therapeutic.
US08349556B2 Use of base-modified deoxynucleoside triphosphates to improve nucleic acid detection
Aspects of the invention provide novel and surprisingly effective methods for the detection of nucleic acids, comprising nucleic acid amplification using base-modified deoxynucleoside 5′-triphosphates (dNTPs). Particular aspects relate to methods for enhancing hybridization properties of oligonucleotide primers and probes in assays detecting nucleic acids, comprise amplifying target DNAs in presence of base-modified duplex-stabilizing deoxyribonucleoside 5′-triphosphates to provide for modified target DNAs, and thereby considerably improving performance of the detection assays. The disclosed methods allow for increasing of the reaction temperature in PCR-based detection systems or, alternatively, reducing the length of the oligonucleotide primers and probes. Certain aspects relates to improvement of real time PCR assays, wherein nucleic acids of interest are detected as the reaction proceeds using fluorescent agents or oligonucleotide FRET probes.
US08349554B2 Needle array assembly and method for delivering therapeutic agents
A fluid delivery device includes an array of needles, each in fluid communication with a respective reservoir. Respective actuators are coupled so as to be operable to drive fluid from the reservoirs via needle ports. Each needle can have a plurality of ports, and the ports can be arranged to deliver a substantially equal amount of fluid at any given location along its length. A driver is coupled to the actuators to selectively control the rate, volume, and direction of flow of fluid through the needles. The device can simultaneously deliver a plurality of fluid agents along respective axes in solid tissue in vivo. If thereafter resected, the tissue can be sectioned for evaluation of an effect of each agent on the tissue, and based on the evaluation, candidate agents selected or deselected for clinical trials or therapy, and subjects selected or deselected for clinical trials or therapeutic treatment.
US08349552B2 Fabricating a flexible rapid blood cooling system
A new blood unit cooling system was designed to cool blood rapidly to about 22° C. and maintain it at about that temperature, even in ambient temperature extremes, for several hours. The system incorporating a preferred eutectic solution including 98% 1-dodecanol, 1.5% myristyl alcohol and 0.5% 1-decanol (having, a melting point of about 23° C.) contained in a sealed flexible polymer layer, was used to cool whole blood-filled bags. The preferred design uses inner and outer containers, each made of transparent polyethylene sheets, where the inner compartments are filled with the solution and sealed, and then placed into each compartment in an outer container, wherein two compartments in the outer container are separated by a flattened and sealed portion of the polyethylene.
US08349545B2 Methods of forming patterns
Some embodiments include methods of forming patterns of openings. The methods may include forming spaced features over a substrate. The features may have tops and may have sidewalls extending downwardly from the tops. A first material may be formed along the tops and sidewalls of the features. The first material may be formed by spin-casting a conformal layer of the first material across the features, or by selective deposition along the features relative to the substrate. After the first material is formed, fill material may be provided between the features while leaving regions of the first material exposed. The exposed regions of the first material may then be selectively removed relative to both the fill material and the features to create the pattern of openings.
US08349544B2 Method of manufacturing semiconductor device
In a method of manufacturing a semiconductor device, a protection film can be formed using a double exposure technology to increase a developer resistance of the protection film without increasing the thickness of the protection film for realizing fine patterning. The method comprises forming a protection film on a first resist pattern formed on a substrate; and forming a second resist pattern on the protection film between parts of the first resist pattern. The protection film is formed in at least two layers by using different methods.
US08349542B2 Manufacturing process of semiconductor device
A resist pattern thickening material has resin, a crosslinking agent and a compound having a cyclic structure, or resin having a cyclic structure at a part. A resist pattern has a surface layer on a resist pattern to be thickened with etching rate (nm/s) ratio of the resist pattern to be thickened the surface layer of 1.1 or more, under the same condition, or a surface layer to a resist pattern to be thickened. A process for forming a resist pattern includes applying the thickening material after forming a resist pattern to be thickened on its surface. A semiconductor device has a pattern formed by the resist pattern. A process for manufacturing the semiconductor device has applying, after forming a resist pattern to be thickened, the thickening material to the surface of the resist pattern to be thickened, and patterning the underlying layer by etching, the pattern as a mask.
US08349536B2 Dithiane derivative, polymer, resist composition, and method for manufacturing semiconductor device using such resist composition
A dithiane derivative, having a structure expressed by the following general formula 1: where R1 is —H, or —CH3, a polymer containing a monomer unit containing the dithiane derivative, a resist composition containing the polymer, and a method for manufacturing a semiconductor device using the resist composition.
US08349532B2 Toner for electrostatic charge image development and method for producing the same
Provided is a toner for an electrostatic charge image development having toner particles which contain: a binder resin; a colorant; and a compound represented by Formula (1) in an amount of 0.1 to 65 ppm based on the total weight of the toner particles: wherein R1 and R2 each respectively represents a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, or an aryl group.
US08349531B2 Compounds and methods of forming compounds useful as a toner
Compounds and methods of forming compounds useful as a toner or toner precursor are disclosed. The compounds may include an aqueous dispersion, the dispersion including: (A) at least one thermoplastic resin; and (B) 0 to 5 weight percent of a stabilizing agent, based on the total weight of (A) and (B). The dispersion may have an average volume diameter particle size from about 0.05 to about 10 microns. A combined amount of the thermoplastic resin and the stabilizing agent may have an acid number of less than 25 mg KOH/g.
US08349528B2 Semiconductor devices and methods of manufacturing thereof
Semiconductor devices and methods of manufacturing thereof are disclosed. A plurality of features is formed on a workpiece, the plurality of features being located in a first region and a second region of the workpiece. Features in the first region have a first lateral dimension, and features in the second region have a second lateral dimension, wherein the second lateral dimension is greater than the first lateral dimension. The first region is masked, and the second lateral dimension of features in the second region is reduced.
US08349525B2 Protective apparatus, mask, mask fabricating method and conveying apparatus, and exposure apparatus
A protective apparatus that protects a predetermined area of the front surface of a mask substrate, provided with a pellicle frame that is disposed on at least a portion of the circumference of the predetermined area and bonded to the front surface of the mask substrate, and a pellicle that is mounted on the pellicle frame so as to cover an opening portion that is formed by the pellicle frame in a manner facing the predetermined area; in which the pellicle frame includes a first side portion and a second side portion, and a third side portion and a fourth side portion that are disposed at different positions along the predetermined area, and in relation to the normal direction of the front surface of the mask substrate, the rigidity of the first side portion and the second side portion is lower than the rigidity of the third side portion and the fourth side portion.
US08349524B2 Hologram recording material and hologram recording medium
The present invention provides a hologram recording material which attains high refractive index change, flexibility, high sensitivity, low scattering, environment resistance, durability, low shrinkage, and high multiplicity, and is suitable for volume hologram recording. Also, the present invention provides a hologram recording medium. A hologram recording material comprising: an organometallic compound at least containing at least two kinds of metals, oxygen, and an aromatic group, and having an organometallic unit wherein two aromatic groups are bonded directly to one metal; metal oxide fine particles; and a photopolymerizable compound. For example, the metal oxide fine particles are selected from the group consisting of silica fine particles, alumina fine particles, titania fine particles, zirconia fine particles, and complex oxide fine particles containing one or more kinds of metal atoms which constitute said four metal oxides. A hologram recording medium 11 has a hologram recording material layer 21.
US08349522B2 Fuel cell
A fuel cell (1) includes an anode (11), a cathode (14), an electrolyte layer (13) containing ceria and provided between the anode (11) and the cathode (14), and at least two intermediate layers containing zirconia and provided between the electrolyte layer (13) and the anode (11). The at least two intermediate layers include a first intermediate layer (18) that contains ceria and a second intermediate layer (19) that has a higher zirconia concentration than the first intermediate layer and is provided between the first intermediate layer and the anode.
US08349519B2 Titanium electrode material and surface treatment method of titanium electrode material
It is an object of the present invention to provide a titanium electrode material which is low in cost and is excellent in electric conductivity, corrosion resistance and hydrogen absorption resistance, and a surface treatment method of a titanium electrode material. A titanium electrode material includes: on the surface of a titanium material including pure titanium or a titanium alloy, a titanium oxide layer having a thickness of 3 nm or more and 75 nm or less, and having an atomic concentration ratio of oxygen and titanium (O/Ti) at a site having the maximum oxygen concentration in the layer of 0.3 or more and 1.7 or less; and an alloy layer including at least one noble metal selected from Au, Pt, and Pd, and at least one non-noble metal selected from Zr, Nb, Ta, and Hf, having a content ratio of the noble metal and the non-noble metal of 35:65 to 95:5 by atomic ratio, and having a thickness of 2 nm or more, on the titanium oxide layer. The surface treatment method of a titanium electrode material includes a titanium oxide layer formation step, an alloy layer formation step, and a heat treatment step.
US08349511B2 Fuel cell
A fuel cell is provided that includes an anode, a cathode, a solid electrolyte layer, a barrier layer, and an intermediate layer. The solid electrolyte layer includes zirconium and is provided between the anode and the cathode. The barrier layer includes cerium and is provided between the solid electrolyte layer and the cathode. The intermediate layer includes zirconium and cerium, and has a first surface facing the solid electrolyte layer, a second surface facing the barrier layer, and pores. The pore ratio of the intermediate layer is higher than the pore ratio of the barrier layer.
US08349510B2 Solid state electrochemical cell having reticulated electrode matrix and method of manufacturing same
A solid state electrochemical cell comprises a dense electrolyte layer; at least one reticulated electrode matrix (REM) of ion-conducting material partially sintered on the gas impermeable electrolyte layer, and electrode material located substantially within the REM. The REM has a majority of pores with an average pore size of less than micron. The REM can also have a porosity of 5 to 80%, thickness at or below 3.00 microns, and a mean grain size of 0.01 to 3.00 microns.
US08349505B2 Power generation system of fuel cell and control method thereof
A fuel cell power generation system of the invention includes a hydrogen supply unit for reforming hydrocarbon fuel to generate reformed gas including hydrogen or generating reaction gas including the hydrogen from a hydrogen material, an oxygen supply unit, a fuel cell for receiving the hydrogen from the hydrogen supply unit and oxygen from the oxygen supply unit, for power generation, temperature sensors each for detecting a temperature of the hydrogen supply unit, and a temperature control unit for adjusting generated power, thereby controlling the temperature of the hydrogen supply unit, based on the detected temperature. The temperature control unit includes a target power setting unit for setting first and second target powers as generated power target values, and a target power switching unit for performing target value switching between the first and second target powers according to a predetermined change in the detected temperature.
US08349500B2 Solvent for dissolving electrolyte salt of lithium secondary battery
There are provided a solvent for dissolving an electrolyte salt of lithium secondary battery comprising at least one fluorine-containing solvent (I) selected from the group consisting of a fluorine-containing ether, a fluorine-containing ester and fluorine-containing chain carbonate, 1,2-dialkyl-1,2-difluoroethylene carbonate (II) and other carbonate (III), a non-aqueous electrolytic solution comprising the solvent and an electrolyte salt, and a lithium secondary battery using the non-aqueous electrolytic solution. The solvent for dissolving an electrolyte salt provides a lithium secondary battery being excellent particularly in discharge capacity, rate characteristic and cycle characteristic and has enhanced incombustibility (safety) and the non-aqueous electrolytic solution comprises the solvent and an electrolyte salt.
US08349499B2 Electrolyte for rechargeable lithium battery and rechargeable lithium battery including the same
An electrolyte for a rechargeable lithium battery, including a lithium salt, an organic solvent, lithium bis(oxalato)borate (LiBOB), and at least one kind of tris(trialkylsilyl)borate represented by following Chemical Formula 1. In the above Chemical Formula 1, R1 to R9 are the same as described in the detailed description.
US08349496B2 Non-aqueous electrolyte secondary battery and method of manufacturing the same
A non-aqueous electrolyte secondary battery having a negative electrode, a non-aqueous electrolyte, and a positive electrode having a positive electrode active material comprising sodium oxide, is characterized in that the sodium oxide contains lithium, and the molar amount of the lithium is less than the molar amount of the sodium.
US08349495B2 Nonaqueous battery with composite negative electrode
A nonaqueous electrolyte battery includes a positive electrode, a negative electrode containing a lithium-titanium composite oxide and a lithium-absorbing material in a weight ratio falling within the range defined in formula (1) given below, and a nonaqueous electrolyte. The lithium-absorbing material has a lithium absorption potential nobler than a lithium absorption potential of the lithium-titanium composite oxide. 3≦(A/B)≦100  (1) Where A denotes the weight (parts by weight) of the lithium-titanium composite oxide, and B denotes the weight (parts by weight) of the lithium-absorbing material.
US08349493B2 Electrochemical cells with improved separator and electrolyte
An electrochemical cell is described. The electrochemical cell includes an anode, a cathode, a separator between said anode and said cathode, and an electrolyte. The electrolyte includes a salt dissolved in an organic solvent. The separator in combination with the electrolyte has an area specific resistance less than 2 ohm-cm2. The electrochemical cell has an interfacial anode to cathode ratio of less than about 1.1.
US08349492B2 Negative electrode for rechargeable lithium battery, and rechargeable lithium battery including same
The negative electrode for a rechargeable lithium battery includes a current collector and a negative active material layer disposed on the current collector. The negative active material layer includes a metal-based negative active material and sheet-shaped graphite and has porosity of 20 to 80 volume %. The negative electrode for a rechargeable lithium battery can improve cell characteristics by inhibiting volume change and stress due to active material particle bombardment during charge and discharge, and by decreasing electrode resistance.
US08349488B2 Secondary battery including a protective circuit board made of metal
A secondary battery has a bare cell including a can, an electrode assembly in the can and a cap assembly sealing the can. A protective circuit module is on the bare cell, the protective circuit module including a metal protective circuit board.
US08349486B2 Lithium secondary battery unit set with bus bar, and lithium secondary battery set with bus bar
The present invention relates to a lithium secondary battery unit set where a plurality of lithium secondary batteries are stacked, and a lithium secondary battery set including a plurality of lithium secondary battery unit sets. The present invention relates to a lithium secondary battery unit set with a bus bar and a lithium secondary battery set with a bus bar. The lithium secondary battery unit set with a bus bar: accommodates and protects a plurality of lithium secondary batteries comprising a pouch and an electrode tab; facilitates the changes of voltage and capacity as the stacked structure of the lithium secondary batteries becomes free; prevents the flow of overcurrent during charging and discharging; and enables uniform temperature distribution of the stacked batteries.
US08349481B2 Power storage apparatus
A power storage apparatus has a power storage element including an electrolyte layer and a plurality of electrode elements stacked with the electrolyte layer interposed between them, and a case accommodating the power storage element and a heat exchange medium for use in heat exchange with the power storage element. The power storage element has an opening portion passing through the power storage element and extending from one end face to the other end face of the power storage element in a stacking direction. A top-face portion of the case located above the power storage element includes an inclined surface inclined with respect to the stacking direction in the power storage element.
US08349477B2 Optical leak detection sensor
A leak detection sensor for detecting a leakage of an electrolyte solution in a flow battery system is provided. The sensor includes a sensor housing, the sensor housing being at least partially surrounded by a fluid and having mounted therein at least one light source. The device also includes at least one light detector, wherein light emitted from at least one light source is incident on a portion of the housing in contact with a fluid and is at least partially refracted by an amount which is dependent on a refractive index of the refractor lens and the surrounding fluid, such that the amount of refraction at the refractor lens and the surrounding fluid causes a loss in a power of light detected by the at least one light detector, the light detector determines the intensity of the detected light, determines the composition of fluid surrounding the device housing based on the based on the difference between the measured light intensity and the intensity of light produced by the light source, and determines a leak if the composition of fluid is determined to be an electrolyte solution.
US08349474B2 Hob cutter with a coating and method for coating hob cutter
The invention relates to a hob cutter tool with a coating, wherein the coating is produced by a physical vapor deposition method, in which in a coating chamber in an atmosphere containing nitrogen, an arc discharge is generated in each case between at least one anode and at least one pure Al cathode on the one hand, and at least one pure Cr cathode on the other hand, and in this way, Al and Cr are vaporized from the cathode, in which the hob cutter tool to be coated is rotated in the coating chamber, wherein the tool is subsequently guided past the at least two cathodes, and in which the vaporized Al and Cr is deposited in atomic or ionized form together with nitrogen from the atmosphere containing nitrogen onto the hob cutter tool led rotating past the cathodes. The coating has a multiplicity of layers, composed of (AlCr)-nitride, arranged on top of each other, wherein the multiplicity of layers is formed from two layer types differing with respect to their Al:Cr ratio, wherein a first layer type has an Al:Cr ratio in the range of 55:45 to 65:35, and a second layer type has an Al:Cr ratio in the range of 70:30 to 74:26, and wherein the two layer types alternate with each other in the coating, wherein each of the layers, in turn is formed from a multiplicity of nanolayers arranged on top of each other, and wherein the coating is connected to the tool base body using a bonding layer. Furthermore, the invention relates to a method for recoating such a hob cutter tool.
US08349473B2 Organic electroluminescent device
An organic electroluminescent device is provided and includes: a cathode; an anode; and at least one organic layer between the cathode and the anode. The at least one organic layer includes a light emitting layer containing at least one light emitting material. A compound represented by the following formula (I) is contained in the at least one organic layer. where n stands for an integer of 2 or greater, L represents an n-valent linking group, and R1, R2, R3, and R4 each independently represents a hydrogen atom or a substituent.
US08349468B2 Metal material for parts of casting machine, molten aluminum alloy-contact member
A Ni alloy layer is formed on a surface of a steel base on the side to be in direct contact with a molten aluminum alloy, and titanium carbide (TiC) is bonded in a particulate state to the surface of the Ni alloy layer. This makes it possible to provide a metal material having materially enhanced melting loss resistance without resorting to conventional techniques, such as the provision of a ceramic coating by PVD or CVD.
US08349461B2 Photo-curing polysiloxane composition and protective film formed from the same
A photo-curing polysiloxane composition includes a polysiloxane, an o-naphthoquinonediazidesulfonate compound, and a solvent. The polysiloxane contains less than 30 wt % of a polysiloxane fraction having a molecular weight above 8,000, and 35 wt % to 60 wt % of a polysiloxane fraction having a molecular weight ranging from 500 to 2,000 when calculated from an integral molecular weight distribution curve obtained by plotting cumulative weight percentage versus molecular weight falling within a range between 500 and 50,000 measured by gel permeation chromatography. A protective film formed from the photo-curing polysiloxane composition and an element containing the protective film are also disclosed.
US08349460B2 Organosilicon copolymer composites, method of manufacture, and articles formed therefrom
Organosilicon composites are described, comprising 30 to 90 vol. % of a cured organosilicon copolymer derived by curing an organosilicon polymer having, in the same copolymer, silicon-containing repeating units comprising a silicon hydride and silicon-containing repeating units comprising a C1-10 ethylenically unsaturated group; and 10 to 70 vol. % of a dielectric filler. The composites are used in the manufacture of circuit subassemblies.
US08349459B2 Infiltration glass containing niobium
The present invention relates to an all-ceramic dental prosthesis in which a porous ceramic matrix material is infiltrated with a glass, having a solubility of <1100 μg/cm2 according to DIN EN ISO 6872. The invention also relates to the use of niobium-containing glass having an Nb2O5 content of more than 0.1% by weight as an infiltration glass for all-ceramic dental compositions.
US08349458B2 Interlayers comprising glycerol based plasticizer
The present invention includes interlayers and multiple layer glazing panels comprising those interlayers, wherein the interlayers comprise poly(vinyl butyral) and a glycerol based plasticizer. The addition of the glycerol based plasticizer surprisingly results in a plasticized poly(vinyl butyral) layer that is suitable for use in a wide range of multiple layer glazing applications.
US08349456B2 Process for preparing articles having anti-fog layer by layer coating and coated articles having enhanced anti-fog and durability properties
Disclosed are processes for preparing articles having anti-fog properties, comprising providing a substrate having at least one main surface coated with an intermediate coating obtained by applying and at least partially curing an intermediate coating composition comprising at least one monoepoxysilane and/or an hydrolyzate thereof and at least one polyepoxy monomer comprising at least two epoxy groups, forming onto said intermediate coating at least one bi-layer, and curing said at least one bi-layer by heating at a temperature of 150° C. or less at atmospheric pressure and in the absence of added water steam. Also disclosed are articles made and/or makeable by these processes.
US08349450B2 Thermal spray powder, method for forming thermal spray coating, and plasma resistant member
A thermal spray powder contains granulated and sintered particles composed of an oxide of any of the rare earth elements having an atomic number from 60 to 70. The average particle size of the primary particles constituting the granulated and sintered particles is 2 to 10 μm. The crushing strength of the granulated and sintered particles is 7 to 50 MPa. A plasma resistant member includes a substrate and a thermal spray coating provided on the surface of the substrate. The thermal spray coating is formed by thermal spraying, preferably plasma thermal spraying, the thermal spray powder.
US08349449B2 Polymer active complex fibers
The invention covers a method of forming functionally active fibers and substrates including functionally active fibers. The method includes forming a mixture of at least one poly vinyl polymer and at least one bleaching active. The mixture is then injected at a controlled flow rate into an electric field to cause the mixture to at least partially form fine fibers that have an average diameter of less than about 1000 nanometers.
US08349448B2 Pressure-sensitive adhesive sheet
The present invention relates to a pressure-sensitive adhesive sheet including: a laminated structure in which a light-shielding layer, a white or silver layer, and a colored layer are laminated in this order; and at least one pressure-sensitive adhesive layer as at least one surface layer, in which at least one surface of the pressure-sensitive adhesive sheet has L* of 30 or more and C* of 3 or more, L* representing a luminosity and C* representing a chromaticness, and in which the pressure-sensitive adhesive sheet as a whole has a transmittance of a light having a wavelength of 550 nm of 0.3% or less. The pressure-sensitive adhesive sheet of the invention is excellent in light-shielding property irrespective of the thinness thereof as well as in decorativity due to the surface thereof that is colored with a bright color.
US08349445B2 Microbicidal substrate
The invention relates to a substrate comprising at least one photocatalytic compound active under the conditions of illuminating an interior of a building or transport vehicle, intended to neutralize the microorganisms with which it comes into contact, and also to its preparation processes and its uses as glazing or another substrate for disinfection, filtration, ventilation, etc.
US08349443B2 Method for treating a substrate
A method for treating a substrate is described. In accordance with one aspect, the method includes applying a polymer coating to a substrate, and bringing the polymer coating into contact with a heated surface in a pressure nip while the coating is still in a wet state. Optionally the polymer coating may include a crosslinkable material, and a crosslinking agent may be used to promote crosslinking. The polymer coating replicates the heated surface. A product produced in accordance with the described method is also disclosed. The product is characterized by having subsurface voids within the coating.
US08349442B2 Agricultural film
To provide an agricultural film which has high transparency and which has a coating film formed with excellent abrasion resistance (adhesion), hydrophilicity (anti-fogging, wettability and anti-fouling) and hydrophilic durability.An agricultural film 10 comprising a base material film 12 and a porous hydrophilic coating film 14 formed on the base material film 12. The hydrophilic coating film 14 contains boehmite particles, silica particles and a binder, wherein (a) the atomic ratio of Al to Si (Al/Si) is from 0.2 to 5.0, (b) the average particle diameter of the silica particles is from 5 to 50 nm, and (c) the crystallite diameter of the boehmite particles, as calculated from the diffraction peak of the (120) plane is from 20 to 50 nm. The hydrophilic coating film 14 is formed by applying a composition comprising boehmite particles, silica particles, a binder and water, on a surface of a base material film, followed by drying.
US08349432B2 Honeycomb structure and method for manufacturing honeycomb structure
A honeycomb structure includes a ceramic block formed by combining a plurality of honeycomb fired bodies together with an adhesive layer interposed between the plurality of honeycomb fired bodies. The plurality of honeycomb fired bodies each has cell walls extending along a longitudinal direction of the honeycomb fired bodies to define cells. The honeycomb fired bodies adjacent to each other via said adhesive layer each have at least one projected portion on the opposing side faces. The projected portions formed on the honeycomb fired bodies overlap each other when seen from an end face of the honeycomb structure and the projected portions formed on the adjacent honeycomb fired bodies abut each other.
US08349431B2 Composite grid with tack film for asphaltic paving, method of paving, and process for making a composite grid with tack film for asphaltic paving
A composite material comprises: an open grid comprising at least two sets of strands. Each set of strands has openings between adjacent strands. The sets are oriented at a substantial angle to one another. A tack film is laminated to the open grid. The tack film has first and second major surfaces, such that a material of the tack film at its first and second major surfaces includes about 50% or more of resinous non-asphaltic component and about 50% or less of asphaltic component.
US08349430B2 Padding system for protecting a home appliance
A padding system for protecting an outer surface of an appliance. The padding system includes a securing device that is attached to opposed first and second ends of a pad. The securing device consists of a first securing member that is releasably attachable to a second securing member when the pad is secured around the outer surface of the appliance. The padding system additionally includes a hand strap that is attached to the first end of the pad. A slit is formed in the pad adjacent to the second end of the pad. The hand strap is passable through the slit to provide a hand grip when the pad is secured around the outer surface of the appliance.
US08349429B2 Films for labels that are removable
Clear and opaque polymeric film structures for providing clear and opaque labels that are removable, respectively. The film structure includes a core layer and first skin layer, wherein the first skin layer contains a polymeric matrix of a material that allows a label, which has been produced from the film structure and applied onto a container or product, to be removed from the container or product by the solution employed in a process for re-using the container. The first skin layer is co-extruded along with the remainder of the layers of the film structure, or the first skin layer is deposited on the film structure as an emulsion or extrusion coating. The first skin layer can be contacted with a water-based adhesive to affix the label onto a particular product or product container. Labels produced from the film structure exhibit a desirable combination of excellent initial adhesion strength, moisture resistance and delaminatability, as well as excellent removability.
US08349425B2 Thin biaxially stretched thin-walled polyester bottle
A biaxially stretched polyester bottle of which a central part of a bottle body portion satisfies at least either (1) that an elongation in the circumferential direction is larger than an elongation in the longitudinal direction in the tensile test at room temperature or (2) that an orientation parameter in the circumferential direction is smaller than an orientation parameter in the longitudinal direction in the Raman spectrometry. Despite the body portion having an average thickness as small as 250 μm or less, the bottle has a drop impact resistance while exhibiting excellent appearance.
US08349417B2 Self-sealing inflatable article
A self sealing inflatable article including an inflatable body portion and a neck portion having an opening, a ring member supporting the opening of the article and a plug member for sealing the opening wherein at least a portion of the body portion of the article is invaginated through the opening of the article with the plug member associated with the invaginated portion.
US08349412B2 Deposition of amorphous silicon films by electron cyclotron resonance
A method is described for forming a film of amorphous silicon (a-Si:H) on a substrate by deposition from a plasma. The substrate is placed in an enclosure, a film precursor gas is introduced into the enclosure, and unreacted and dissociated gas is extracted from the enclosure so as to provide a low pressure in the enclosure. Microwave energy is introduced into the gas within the enclosure to produce a plasma therein by distributed electron cyclotron resonance (DECR) and cause material to be deposited from the plasma on the substrate. The substrate is held during deposition at a temperature in the range 200-600° C., preferably 225-350° C. and a bias voltage is applied to the substrate at a level to give rise to a sheath potential in the range −30 to −105V, preferably using a source of RF power in the range of 50-250 mW/cm2 of the area of the substrate holder.
US08349409B2 Pattern forming method, method for forming composite-metal oxide film and method for coating two-liquid reaction curing type adhesive
A liquid droplet of a first liquid and a liquid droplet of a second liquid are mixed upon landing on a substrate, and then the reaction is initiated between the first and second liquid droplets. Accordingly, it is possible to avoid the problem which would have been caused when the two liquids are mixed in advance before the usage that the reaction between the two liquids is advanced before the liquids are actually coated. Further, since the ink-jet system is employed, it is possible to precisely control the liquid-droplet amount and the landing position, thereby landing the first and second liquids on a same position with high precision. Accordingly, a highly integrated pattern can be formed. Furthermore, since the mixing ratio of the first and second liquids can be precisely controlled, the film quality can be stabilized.
US08349408B2 Method of protecting reactor components from fouling
A method of protecting a reactor component from fouling includes forming an oxide layer on a metal foil to achieve an antifouling liner. The antifouling liner may be manipulated into a shape that conforms to one or more surfaces of the reactor component that are contacted by a fluid during reactor operation. The metal foil portion of the antifouling liner is secured to the surface(s) of the reactor component by suitable means. As a result, the oxide layer portion of the antifouling liner is exposed to the fluid in the reactor, thereby reducing or preventing the fouling of the component.
US08349404B2 Methods for growing and harvesting carbon nanotubes
A method for directly growing carbon nanotubes, and in particular single-walled carbon nanotubes on a flat substrate, such as a silicon wafer, and subsequently transferring the nanotubes onto the surface of a polymer film, or separately harvesting the carbon nanotubes from the flat substrate.
US08349402B2 Applying vapour phase aluminide coating on airfoil internal cavities using improved method
A method of applying an aluminide coating to an internal cavity of a metal part, such as an airfoil. The method includes inserting a perforated sealed container containing a source of aluminide into the internal cavity and vaporizing the aluminide source to form an aluminide coating on the wall surface of the cavity.
US08349400B2 Method of making a composite porous material
Methods of making porous composite materials are provided. These methods involve providing a sintered porous first polymeric material, providing a solution containing a second polymeric material dissolved in a solvent, and, depositing the solution onto the sintered porous first polymeric material to form a precipitated porous second polymeric material wherein a portion of the second polymeric material is fused to the sintered, porous first polymeric material by at least one direct physical bond, and the second polymeric material is in at least some of the pores of the first polymeric material. In some methods, the first polymeric material and the second polymeric material are soluble in the same solvent.
US08349395B2 Electrically conductive steel-ceramic composite and process to manufacture it
The invention relates to a electrically conductive steel-ceramic connection comprising a steel interconnector and an electrically conductive ceramic joining layer arranged thereon. The interconnector comprises a ferritic steel containing Cr in a quantity ranging from 18 to 24% by weight. The ceramic layer contains perovskite of a formula Ln1-xSrxMn1-yCoyO3-δ or Ln1-xSrxFe1-yCoyO3-δ, wherein 0.1≦x≦0.4, 0.1≦y≦0.6, 0≦δ≦x/2 and Ln=La—Lu. The inventive steel-ceramic connection is usable for a high-temperature fuel cell and regularly exhibits good adhesive properties and a low transition resistance (initial transition resistance R approximately equal to 0.01 Ωcm2). Said steel-ceramic connection makes it possible to advantageously introduce a ferritic steel into high-temperature fuel cells. The inventive method for producing said steel-ceramic connection consists in pre-treating an inserted ceramic powder exhibiting good sinterability during an assembly process and during the fuel cell operation.
US08349393B2 Silver plating in electronics manufacture
Compositions and methods for silver plating onto metal surfaces such as PWBs in electronics manufacture to produce a silver plating which is greater than 80 atomic % silver, tarnish resistant, and has good solderability.
US08349387B2 Method for production of coated preparations
The present invention relates to a method for production of a coated preparation, characterized by coating a core material with a coating solution, the core material comprising an active ingredient, the coating solution comprising a) a resin composition obtained by copolymerization of polyvinyl alcohol having an average polymerization degree of 1300 or less, and at least one polymerizable vinyl monomer in a weight ratio of 6:4 to 9:1, b) water, and c) an organic solvent. The method for production make it feasible to efficiently coat a preparation such as a tablet, a granule, and a fine granule, etc. (a pharmaceutical drug, an animal drug, an agricultural chemicals, a fertilizer, or a food product) with the coating solution comprising a) the composition comprising the polyvinyl alcohol copolymer as the main component, b) water, and c) the organic solvent.
US08349386B2 Functional serum protein product for use in infant food and therapeutic compositions and methods for the preparation thereof
The invention relates to a serum protein product, suitable as an ingredient for foods and therapeutic compositions, in particular infant and baby foods. The invention also provides a method for the preparation of the serum protein product, based on micro filtration of milk. The invention provides a method for the preparation of a serum protein product, comprising the preparation of a permeate through micro filtration of cow's milk at a temperature of between 10 and 20° C. utilizing a membrane having a pore size of between 0.3 and 0.5 μm.
US08349385B2 Milk component-based sweet comprising defined edible fat agglomerates, and method and device for the production thereof
The invention relates to a sweet that has a long shelf life and is provided in the form of a soft, creamy, shape-retaining, and foamed mass comprising milk components, edible fats, sugar and/or sugar substitutes, and water. At least one portion of the edible fat is provided in a crystallized form at ambient temperature. The inventive sweet does not contain any lactose crystals that can be perceived by the consumer. The milk protein content amounts to 5.5 to 20% by weight while the fat-free dry milk content ranges between 14 and 55% by weight and the degree of denaturation of the whey protein amounts to ≦10%. The inventive sweet is characterized by the fact that the crystallized and non-crystallized edible fat agglomerates have a volume-related particle size D50.3 of 3.5 to 18 μm.
US08349380B2 Bromine-based biocides suitable for food processing
Ultraviolet light stabilized antimicrobial compositions are formed from (A) and (B). (A) is (I) a solid-state microbiocidal compound having at least one bromine atom in the molecule; (II) an aqueous solution or slurry of (I); (III) is a concentrated aqueous antimicrobial composition having a dissolved active bromine content derived from (i) BrCl or BrCl and Br2 and (ii) overbased alkali metal sulfamate and/or sulfamic acid, alkali metal base, and water, (IV) solids made by dewatering a composition of (III). (B) is a ultraviolet light degradation-inhibiting amount of up to one part by weight of ascorbic acid, dehydroascorbic acid and/or an edible water-soluble salt/ester thereof per part by weight of bromine in the selected antimicrobial composition. Preparation and uses of such compositions are described. Methods of controlling contamination of seafood and seafood products by pathogens are also described.
US08349379B2 Cream cheese product and its method of preparation
The invention relates to a cream cheese product obtainable by a process comprising the steps of: (a) acidifying a whey protein concentrate with a food grade acidulant or with starter bacteria to reduce the pH to more than 4.5 to about 5.2, (b) heating the acidified whey protein concentrate of step (a) slowly to a temperature of about 75° to about 90° C. and maintaining it for at least about 30 min to produce a 1.5 functional whey protein concentrate, (c) optionally blending the whey protein concentrate of step (b) with milk fat in a weight ratio of about 60:40 to about 100:0 wherein step (c) may be carried out before step (b), (d) homogenizing the blend obtained in step (b) or (c) in a 2-stage high-pressure homogenizer at pressures of about 300-400/50-80 bar and a temperature of about 5° to about 75° C. to produce an emulsified functional whey protein concentrate, (e) blending the product of step (d) with curd the fat content of which is adjusted in accordance with the milk fat portion added in step (c) and with the desired product, and adding salt and optional stabilizers, and (f) homogenizing the product of step (e) in a 2-stage high pressure homogenizer at pressures of about 300-400/508-80 bar and at a temperature of about 68° to about 90° C.
US08349375B2 Water soluble pharmaceutical compositions of hops resins
The present invention is drawn to water-soluble compositions for providing hops constituents, particularly alpha acids, iso-alpha acids, and beta acids. A pharmaceutical gel composition can comprise a hops extract and a surfactant. Such compositions can be formulated into products for various therapeutic applications, including oral and topical uses. Such compositions can also be dissolved in water to yield a clear solution containing more dilute hops acids. The invention also provides methods of treatment comprising administering water-soluble hops compositions. The present invention is also drawn to methods for making water-soluble preparations of hops constituents.
US08349374B2 Inhibition of angiogenesis and destruction of angiogenic vessels with extracts of noni juice (Morinda citrifolia)
Noni juice and a protein-free, alcohol precipitate of Noni juice inhibited angiogenesis in in vitro human angiogenesis models. When growth medium contained Noni juice at least over the range from about 2.5% to about 33% (by volume), angiogenesis was blocked. Moreover, Noni juice and an ethanol precipitate were able to destroy a pre-existing angiogenic response as well as prevent the development of new vessels. Noni juice was effective in inhibiting the growth of angiogenic vessels from breast cancer explants. It will also be effective in treating cancers and non-cancerous diseases whose response includes an increase in angiogenesis, e.g., retinopathy of prematurity, neovascular glaucoma, diabetic retinopathy, and psoriasis. In an initial experiment, Noni juice was effective in treating lesions associated with psoriasis. The primary antiangiogenic component is believed to be a carbohydrate with a molecular weight less than about 6000 Daltons. In an initial experiment, oral administration of Noni juice appeared to adversely affect the antiangiogenic component(s) in the juice.
US08349371B2 Method for anti-oxidation, inhibiting activity and/or expression of matrix metalloproteinase, and/or inhibiting phosphorylation of mitogen-activated protein kinase using neonauclea reticulata leaf extracts
A method of inhibiting at least one selected from the group consisting of oxidation, the activity of matrix metalloproteinase (MMP), the expression of matrix metalloproteinase, and the phosphorylation of mitogen-activated protein kinase (MAP kinase) in a mammal, comprising administrating to the mammal an effective amount of a Neonauclea reticulate leaf extract, is provided.
US08349362B2 Dosage forms for tamper prone therapeutic agents
A dosage form from which a burst release of a drug contained within a tampered dosage form is reduced or retarded by the presence in or on the dosage form of a TPTA (Tamper Prone Therapeutic Agent) trap. If the dosage form has not been tampered with, the TPTA trap does not significantly interfere with the rate of release of the drug from the dosage form. However, if the dosage form has been physically tampered with, the TPTA trap reduces or retards burst release of the drug from the dosage form.
US08349361B2 Composition for rapid disintegrating tablet in oral cavity
The present invention provides rapid disintegrating tablets in oral cavity having a shortened disintegration time in oral cavity as well as a sufficient hardness with compared to rapid disintegrating tablets of the prior art.The above objective is solved by a composition for rapid disintegrating tablets in oral cavity, wherein components (a) to (c) are contained in such manner that (a) saccharides consisting of a combination of mannitol and xylitol is 40 to 90 parts by weight; (b) the inorganic excipient is 1 to 30 parts by weight; and (c) the disintegrating agent is 5 to 40 parts by weight, provided that the total amount of (a), (b) and (c) is 100 parts by weight.
US08349358B1 Transdermal anesthetic applicator having thermochromic indication
A transdermal analgesic applicator configured to provide a visual signal subsequent sufficient absorption of an analgesic compound ensuing the transdermal analgesic applicator being applied to the skin of a patient. The transdermal analgesic applicator includes a first layer that is impermeable and has integrally formed therewith on at least a portion thereof a plurality of microcapsules containing a thermochromic dye mixture. The first layer having the portion of microcapsules presents a first color at ambient room temperature and a second color at temperature greater than the first temperature as a result of being placed on the skin of a patient. A second layer containing an analgesic compound is secured to the first layer. The first layer changes from the first color to the second color subsequent the first layer changing from the first temperature to the second temperature, which the rate of temperature change is approximately equivalent to the absorption rate of the analgesic compound.
US08349354B2 Composite layered hemostasis device
The present invention is directed to a hemostatic composite structure having a bioabsorbable fabric or non-woven substrate having at least two major oppositely facing surface areas and a continuous non-porous polymer-based film that is laminated on one major surface of said substrate. The bioabsorbable fabric substrate can be an oxidized polysaccharide and/or the non-woven substrate can be made from bioabsorbable, non-cellulosic derived polymers. The continuous non-porous polymer based film can be a bioabsorbable polymer. The present invention also relates to a method for providing hemostasis by applying a composite structure described herein onto a wound site in need of a hemostatic device wherein a major surface of the substrate without the film layer is applied onto the wound site.
US08349353B2 Controlled release cytotoxic agent compositions and methods for the treatment of otic disorders
Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with cytotoxic agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
US08349350B2 Coatings for drug delivery devices
A polymer coating for medical devices based on a polyolefin derivative. A variety of polymers are described to make coatings for medical devices, particularly, for drug delivery stents. The polymers include homo-, co-, and terpolymers having at least one olefin-derived unit and at least one unit derived from vinyl alcohol, allyl alcohol and derivatives thereof.
US08349347B2 Capsule medication administration system and medication administration method
A capsule medication administration system includes: a first capsule for internal body marking; a second capsule for medication; a marking device which makes a marking within a living body; a drug retention section which retains a drug; a release device which releases the drug; a detection device which detects the marking; a decision device which decides whether or not a marking which has been detected by the detection device is a specified marking; and a release control device which operates the release device, if it has been decided by the decision device that it is the specified marking; wherein the first capsule comprises the marking device. The second capsule comprises the drug retention section and the release device.
US08349330B2 Therapeutic use of anti-CS1 antibodies
The present invention is directed to antagonists of CS1 that bind to and neutralize at least one biological activity of CS1. The invention also includes a pharmaceutical composition comprising such antibodies or antigen-binding fragments thereof. The present invention also provides for a method of preventing or treating disease states, including autoimmune disorders and cancer, in a subject in need thereof, comprising administering into said subject an effective amount of such antagonists.
US08349329B2 Antibodies that bind to PRO286
The invention relates to the identification and isolation of novel DNAs encoding the human Toll proteins PRO285, PRO286, and PRO358, and to methods and means for the recombinant production of these proteins. The invention also concerns antibodies specifically binding the PRO285, or PRO286, or PRO358 Toll protein.
US08349328B2 Rodent control agents comprising antibodies that binds to rodent specific peptide epitopes
The present invention relates to novel rodent control agents comprising antibodies, or antigen-binding fragments thereof, that bind to proteins expressed in rodents and in particular antibodies or antigen-binding fragments that bind to proteins expressed in the gastrointestinal (GI) tract of rodents, as well as to methods of making such novel rodent control agents. The invention further extends to novel antibodies and antigen-binding fragments for use in rodent control as well as to methods of controlling rodents through the use of such antibodies, antigen binding fragments and novel rodent control agents.
US08349327B2 Method for treating muscular dystrophy using antagonist antibodies against GDF-8
The disclosure provides novel molecules related to growth and differentiation factor-8 (GDF-8), in particular mouse and humanized antibodies, and antibody fragments, including those that inhibit GDF-8 activity and signaling in vitro and/or in vivo. The disclosure also provides methods for diagnosing, treating, ameliorating, preventing, prognosing, or monitoring degenerative orders of muscle, bone, and insulin metabolism, etc., in particular amyotrophic lateral sclerosis (ALS). In addition, the disclosure provides pharmaceutical compositions for the treatment of such disorders by using the antibodies, polypeptides, polynucleotides, and vectors of the invention.
US08349325B2 Soluble FMS-like tyrosine kinase-1 (sFLT-1) antibody and related composition, kit, methods of using, and materials and method for making
An isolated antibody that specifically binds to sFlt-1 or a fragment thereof having (i) a variable heavy domain region comprising the amino acid sequence of SEQ ID NO: 2, (ii) a variable light domain region comprising the amino acid sequence of SEQ ID NO: 4, or (iii) both (i) and (ii), a pharmaceutical composition and a kit comprising such an antibody, a method of making such an antibody, a method of determining the presence, amount or concentration of sFlt-1 or a fragment thereof in a test sample, a method of treating a patient in therapeutic or prophylactic need of an antagonist of sFlt-1, an isolated nucleic acid comprising a nucleotide sequence encoding the amino acid sequence of (i) SEQ ID NO: 2, (ii) SEQ ID NO: 4, or (iii) both (i) and (ii), optionally as part of a vector, and a host cell comprising and expressing such a nucleic acid.
US08349321B2 Immunoglobulin formulation and method of preparation thereof
A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
US08349318B2 Use of specifically engineered enzymes to enhance the efficacy of prodrugs
The invention provides methods for enhancing efficiency of prodrugs by specifically engineered enzymes with altered or enhanced activity and broader substrate specificity towards nucleoside analogs used in cancer chemotherapy, and delivering the enzymes to specific target cells in a patient. The invention also provides modified deoxycytidine kinase (dCK) mutants with such enhanced activities. Furthermore, the invention provides antibody-conjugated enzymes, pharmaceutical composition and kit containing the same, that can be specifically delivered to tumor cells.
US08349313B2 Dairy composition with probiotics and anti-microbial system
Dairy compositions are provided having a high pH, of about 4.8 to about 6.2, comprising desirable probiotic cultures as well as an anti-microbial system for inhibiting undesirable pathogenic and/or spoilage microbial growth without significantly reducing the beneficial effect of the probiotic cultures.
US08349312B2 Proline substituted cyclosporin analogues
The present invention provides novel proline substituted cyclosporinanalogue compounds, pharmaceutical compositions comprising these compounds and methods of using these compounds for the treatment of disorders and diseases, including immune disorders, inflammatory disorders and viral infections.
US08349310B2 Attractant compositions and method for attracting biting insects
1,5-octadien-3-ol is an attractant for biting insects, particularly mosquitoes and may be used alone or with other attractants.
US08349308B2 Modified polymers for delivery of polynucleotides, method of manufacture, and methods of use thereof
A polynucleotide delivery vehicle comprising a modified polymer is provided herein, the modified polymer having the following formula: in which W1, W2, W3, W4, W5, W6, Z1, Z2, Z3, Z4, Z5, Z9, R1, R2, R3, R4, R5, n1, n2, n3, n4, n5, and n6 are defined herein. Also disclosed are methods of delivering a polynucleotide to the cytoplasm of a selected tissue type or cell type and methods of reducing expression of a gene in a cell or a subject in need thereof with the modified polymer.
US08349306B2 Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery
The present invention relates to an amphiphilic block copolymer of a hydrophilic block and a hydrophobic block with a terminal hydroxyl group wherein the terminal hydroxyl group of the hydrophobic bock is substituted with a tocopherol or cholesterol group. It also relates to polymeric compositions capable of forming stable micelles in an aqueous solution, comprising the amphiphilic block copolymer and a polylactic acid derivative wherein one or more ends of the polylactic acid are covalently bound to at least one carboxyl group.
US08349304B1 Evaporative cooling composition
A liquid evaporative cooling composition, for providing relief from heat-related discomfort in humans and animals, is generated by means of a concentrate, dissolved in water, which preferably consists essentially of: (a) about forty-three percent by weight of an alcohol; (b) about twelve percent by weight of a surfactant; (c) about four percent by weight of an aromatic oil; (d) about one percent by weight of a cooling agent; and (e) about forty percent by weight of water.
US08349302B2 Shampoo containing a gel network and a non-guar galactomannan polymer derivative
Shampoo compositions comprise (a) from about 5% to about 50% of one or more detersive surfactants; (b) a dispersed gel network phase comprising: (i) at least about 0.05% of one or more fatty amphiphiles; (ii) at least about 0.01% of one or more secondary surfactants; and (iii) water; (c) at least about 0.05% of a galactomannan polymer derivative with a net positive charge and having a mannose to galactose ratio of greater than 2:1 on a monomer to monomer basis, wherein the galactomannan polymer derivative has: (i) a molecular weight from about 1,000 to about 10,000,000; and (ii) a cationic charge density from about 0.7 meq/g to about 7 meq/g; and (d) at least about 20% of an aqueous carrier; all by weight of the shampoo composition.
US08349299B2 Conditioning agent and a method for making hair having a shape memory effect
A method of imparting a shape memory effect to hair may include administrating an effective amount of a hair-conditioning agent to hair. The hair-conditioning agent may include a shape memory polymer selected from the group consisting of a polyurethane, an acrylic acid copolymer, a pyridine-based copolymer, and a pyrrolidone copolymer.
US08349295B2 Surface modified aerosol particles, a method and apparatus for production thereof and powders and dispersions containing said particles
A method and apparatus for multicomponent surface modified aerosol particle production suitable for, for instance, therapeutic, cosmetic or diagnostic use in which an aerosol containing an active agent is introduced in an aerosol reactor together with a surface agent or surface agent source and/or precursor and wherein the surface agent and/or surface agent precursor is volatilizable. The surface agent vapor saturation ratio is elevated so to cause it to nucleate from the gas phase. Reactor conditions are maintaining such that the active agent remains in the condensed phase and provides a surface for the surface agent to deposit on the active agent containing aerosol particle thus producing surface modified aerosol particles. The method can be used for batch or continuous production. Particles made according to the method and powders and dispersions containing the particles are also described.
US08349293B2 Use of metal nanoparticles in the diagnosis of Alzheimer's disease
The invention relates to the use of metal nanoparticles for the preparation of a composition for diagnosing Alzheimer's disease by MRI.