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US08319386B2 |
Motor
A motor having a rotor and a stator is disclosed. A motor having a rotor and as stator is disclosed. The rotor is a consequent-pole rotor having a rotor core, a plurality of magnets, and a plurality of salient poles. The stator includes a plurality of teeth. The stator is arranged to be opposite to the rotor with a gap along the radial direction. The gap between the stator and the rotor is set to satisfy an expression 1 |
US08319385B2 |
Method and bearing for supporting rotatable devices, particularly a medical scanner
A method is provided for supporting rotatable devices, particularly a medical scanner having an inner ring and an outer ring. According to the invention, the inner ring and outer ring are guided without contact in the axial and/or radial direction by the magnetic field of electromagnets, and the distance between them is monitored and controlled by means of distance sensors. For a bearing implementing said method according to the invention, the outer ring is made in multiple parts and has a U-shaped cross section that is open to the inside in the assembled state, into which the inner ring (1, 10, 11) extends, and electromagnets and distance sensors are disposed in the axially and radially opposite areas of the inner ring or outer ring. |
US08319384B2 |
Electromechanical brake actuator motor brake
In some examples, a system includes a brake rotor, a brake armature configured to engage with the brake rotor to substantially fix a rotational position of the brake rotor relative to the brake armature, and a mechanism mechanically coupled to the brake armature. The brake armature may be configured to rotate in a first rotational direction and a second rotational direction substantially opposite the first rotational direction. The mechanism may be configured to maintain the brake armature in a fixed rotational position when a torque applied to the brake armature in a second rotational direction is less than or equal to a threshold torque value. The mechanism also may be configured to permit rotation of the brake armature in the second rotational direction when torque on the brake armature in the second rotational direction exceeds the threshold torque value. |
US08319381B2 |
Automotive electric motor-generator with radial plates and circuit boards disposed in a fan shape in a common plane around shaft of rotor
The present invention provides an automotive electric motor-generator that can achieve sufficient cooling of a radiating plate by ensuring a sufficient cooling airflow ventilation channel within limited axial or radial dimensions. In the present invention, first and second radiating plates each form a fan shape, have N-channel power MOSFETs mounted thereto, and have a drain potential for the power MOSFETs. A first circuit board includes insert conductors that connect the power MOSFETs in series, and a second circuit board has insert conductors that are connected to source terminals of the power MOSFETs and that have negative potential. The first radiating plate, the second radiating plate, the first circuit board, and the second circuit board are disposed in a fan shape that is centered around a shaft so as to line up radially in a plane that is perpendicular to the shaft outside one axial end of a rear housing. |
US08319378B2 |
Method and apparatus for improved burst mode during power conversion
A method and apparatus for power conversion. In one embodiment, the apparatus comprises a DC-AC conversion stage; an intermediate capacitor coupled across the DC-AC conversion stage; and a burst mode controller coupled to the intermediate capacitor and the DC-AC conversion stage, wherein the burst mode controller (i) maintains a voltage of the intermediate capacitor below a preset limit during a storage period and (ii) drives the DC-AC conversion stage to convert DC input to AC output during a burst period, wherein the storage and burst periods occur during a burst mode operation. |
US08319376B2 |
Contactless power transmission circuit
A driving circuit drives a switching element such that an ON-period of the switching element is shorter when a power receiving device is detected not to be placed than when the power receiving device is placed. |
US08319372B2 |
EIB protocol in an integrated power distribution system
An electrical distribution system for selectively connecting an electrical power source to load devices comprises a plurality of panels. Each panel comprises a plurality of load control devices each for connection in a branch circuit to a load device, and an input/output (I/O) controller operatively connected to each of the load control devices for controlling operation of the load control devices. The I/O controller includes a communication port. A programmed system controller is provided for commanding operation of the I/O controllers and includes a communication port. A bus operatively connects the I/O controller communication ports to the system controller communication port. The programmed system controller implements a communication program using a protocol establishing communications on the bus, the protocol including a layer stack translating between logical messages and physical messages for communication on the bus, wherein each layer generates its own thread and communicates to other layers via objects passed in queues to adjacent layers. |
US08319371B2 |
Electronic device
An electronic device includes alight emitting unit that provides backlight to a liquid crystal display unit, a communication unit that transmits video data, and a control unit that controls a current flowing from a DC-DC converter to the light emitting unit. The control unit controls the current flowing from the DC-DC converter to the light emitting unit so as to change an output voltage of the DC-DC converter from a first voltage to a second voltage which is lower than the first voltage. The first voltage is supplied to the light emitting unit and the second voltage is supplied to the communication unit. |
US08319364B2 |
Stress analysis device for wind-turbine structure, computer-readable storage medium storing stress analysis program, and wind turbine generator system
Provided is a stress analysis device 3 for a wind-turbine structure, which includes a load-data generating section 21 that generates load time-series data of a predetermined load observation point, set in the wind-turbine structure, on the basis of a parameter related to an operating environment, and a stress analyzing section 22 that generates stress time-series data of at least one target analysis point, set in the wind-turbine structure, on the basis of the load time-series data. |
US08319363B2 |
Wind power generator
A wind power generator includes a pillar fixed on a base, a nacelle platform disposed on an upper end portion of the pillar, a service crane provided at a side of the nacelle platform, a generator assembly coupled to the nacelle platform, a rotor hub rotatably coupled to the generator assembly, and a plurality of blades coupled to the rotor hub and rotating the rotor hub. The rotor hub is provided at an outer circumference of a front end thereof with a plurality of first pulleys for guiding a case from a winch installed on the ground. |
US08319355B2 |
Light emitting device
Disclosed herein is a light emitting device, which includes a first substrate, a protective layer, a second substrate, a buffer member and a sealant. The first substrate has an illuminating member thereon. The protective layer covers the illuminating member and has a first coefficient of thermal expansion. The second substrate is disposed over the protective layer. The buffer member is disposed between the first and second substrates and surrounds the protective layer, wherein the buffer member has a second coefficient of thermal expansion which is less than the first coefficient. The sealant surrounds the buffer member and seals off the space between the first and second substrates, wherein the sealant has a third coefficient of thermal expansion which is less than the second coefficient. |
US08319352B2 |
Semiconductor device
A memory card has a wiring board, four memory chips stacked on a main surface of the wiring board, and a controller chip and an interposer mounted on a surface of the memory chip of the uppermost layer. The memory chips are stacked on the surface of the wiring board so that their long sides are directed in the same direction as that of the long side of the wiring board. The memory chip of the lowermost layer is mounted on the wiring board in a dislocated manner by a predetermined distance in a direction toward a front end of the memory card so as not to overlap the pads of the wiring board. The three memory chips stacked on the memory chip of the lowermost layer are disposed so that their short sides on which pads are formed are located at the front end of the memory card. |
US08319346B2 |
Semiconductor structure and manufacturing method of semiconductor structure
Disclosed is a semiconductor structure including a semiconductor substrate including an electronic circuit which is provided in a predetermined region of the semiconductor substrate; a wall which is formed to encircle the predetermined region of the semiconductor substrate; a wiring provided in a region of the semiconductor substrate outside of the predetermined region of the semiconductor substrate; an external connection electrode provided on the wiring; a sealing resin which seals the wiring, the sealing resin being filled in the region of the semiconductor substrate outside of the wall; and a transparent resin to seal the predetermined region of the semiconductor substrate, the transparent resin being filled inside of the wall. |
US08319344B2 |
Electrical device with protruding contact elements and overhang regions over a cavity
A device with contact elements. One embodiment provides an electrical device including a structure defining a main face. The structure includes an array of cavities and an array of overhang regions, each overhang region defining an opening to one of the cavities. The electrical device further includes an array of contact elements, each contact element only partially filling one of the cavities and protruding from the structure over the main face. |
US08319341B2 |
Semiconductor device with gate structure
A gate structure of a semiconductor device includes an intermediate structure, wherein the intermediate structure includes a titanium layer and a tungsten silicide layer. A method for forming a gate structure of a semiconductor device includes forming a polysilicon-based electrode. An intermediate structure, which includes a titanium layer and a tungsten silicide layer, is formed over the polysilicon-based electrode. A metal electrode is formed over the intermediate structure. |
US08319338B1 |
Thin stacked interposer package
The present invention comprises a semiconductor package comprising a bottom semiconductor package substrate which is populated with one or more electronic components. The electronic component(s) of the bottom substrate are covered or encapsulated with a suitable mold compound which hardens into a package body of the semiconductor package. The package body is provided with one or more vias through the completion of laser drilling process, such via(s) providing access to one or more corresponding conductive contacts of the bottom substrate. These vias are either lined or partially filled with a conductive metal material. Subsequently, a top semiconductor package substrate (which may optionally be populated with one or more electronic components) is mounted to the package body and electrically connected to the conductive metal within the via(s) of the package body. |
US08319337B2 |
Conductive structure for a semiconductor integrated circuit and method for forming the same
A conductive structure for a semiconductor integrated circuit and method for forming the conductive structure are provided. The semiconductor integrated circuit has a pad and a passivation layer partially covering the pad to define a first opening portion having a first lateral size. The conductive structure electrically connects to the pad via the first opening portion. The conductive structure comprises a support layer defining a second opening portion. A conductor is formed in the second opening portion to serve as a bump having a planar top surface. |
US08319335B2 |
Power semiconductor module, power semiconductor module assembly and method for fabricating a power semiconductor module assembly
The invention relates to a power semiconductor module including a power semiconductor chip arranged on a substrate and comprising a bottom side facing the substrate, a top side facing away from the substrate, and an electrical contact face arranged on the top side. A bond wire is bonded to the contact face. At least when the power semiconductor module is fastened to a heatsink, a contact pressure element creates a contact pressure force (F) acting on a sub-portion 36 of a bond wire portion configured between two adjacent bond sites. The contact pressure force (F) results in the power semiconductor chip and a substrate beneath being pressed against the heatsink. |
US08319328B2 |
Method of manufacturing a semiconductor device
Chipping of semiconductor chips is to be prevented. A semiconductor device comprises a semiconductor chip having a main surface, a plurality of pads formed over the main surface, a rearrangement wiring formed over the main surface to alter an arrangement of the plurality of pads, and a protective film and an insulating film formed over the main surface, and a plurality of solder bumps each connected to the rearrangement wiring and arranged differently from the plurality of pads. The presence of a bevel cut surface obliquely continuous to the main surface and formed on a periphery of the main surface of the semiconductor chip prevents chipping. |
US08319323B2 |
Electronic package having down-set leads and method
In one embodiment, a leadless package includes down-set conductive leads having base portions. The base portions include stand-offs that attach to electrodes on an electronic chip using, for example, a solder die attach material. An optional encapsulating layer covers portions of the down-set conductive leads and portions of the electronic chip while leaving pad portions of the down-set conductive leads and a surface of the electronic chip exposed. The pad portions and the surface of the electronic chip are oriented to attach to a next level of assembly. |
US08319322B2 |
Substrate for semiconductor element, method for manufacturing substrate for semiconductor element, and semiconductor device
Provided is a manufacturing method of a semiconductor element substrate including: a step of forming a first photoresist pattern on a first surface of a metallic plate, to form a semiconductor element mounting part, a semiconductor element electrode connection terminal, a wiring, an outer frame part, and a slit; a step of forming a second photoresist pattern on the second surface of the metallic plate; a step of forming the slit by half etching to connect the metallic chip with a four corners of the outer frame part; a step of forming a plurality of concaved parts on the second surface of the metallic plate; a step of forming a resin layer by injecting a resin to the plurality of concaved parts; and a step of etching the first surface of the metallic plate and forming the semiconductor element electrode connection terminal and the outer frame. |
US08319313B1 |
Circuits, systems, and methods for reducing effects of cross talk in I/O lines and wire bonds
Circuits, architectures, a system and methods for reducing the effect(s) of cross talk in neighboring I/O signal paths. The circuitry generally includes first and second input/output (I/O) pads having first and second I/O signal lines coupled thereto, and a capacitor having first and second terminals coupled to the first I/O pad and/or signal line and the second I/O pad and/or signal line, respectively. The method generally comprises the steps of (1) transmitting or receiving a signal along a first I/O signal line in an integrated circuit, the first I/O signal line communicating with a first I/O pad on the integrated circuit, and the integrated circuit having a second I/O signal line communicating with a second I/O pad; and (2) capacitively coupling the first signal to the second I/O pad and/or the second I/O signal line, sufficiently to reduce the effect(s) of cross talk in the second I/O signal line. The present invention can significantly reduce the effects of cross talk in neighboring I/O signal paths, for both input and output signals. |
US08319311B2 |
Hybrid STI gap-filling approach
A method of forming an integrated circuit structure includes providing a semiconductor substrate including a top surface; forming an opening extending from the top surface into the semiconductor substrate; and performing a first deposition step to fill a first dielectric material into the opening. The first dielectric material is then recessed. A second deposition step is performed to fill a remaining portion of the opening with a second dielectric material. The second dielectric material is denser than the first dielectric material. The second dielectric material is recessed until a top surface of the second dielectric material is lower than the top surface of the semiconductor substrate. |
US08319310B2 |
Field effect transistor gate process and structure
A Schottky gate (27′, 27″) of a metal-semiconductor FET (20′, 20″) is formed on a semiconductor comprising substrate (21) by, etching a gate recess (36) so as to expose a slightly depressed surface (362) of the substrate (21), the etching step also producing surface undercut cavities (363) extending laterally under the etch mask (43) from the gate recess (36), then conformally coating the slightly depressed surface (362) with a first Schottky forming conductor (40′) and substantially also coating inner surfaces (366) of the surface undercut cavities (363), and forming a Schottky contact to the semiconductor comprising substrate (21), adapted when biased to control current flow in a channel (22) extending between source (23) and drain (24) of the FET (20′, 20″) under the gate recess (36). In further embodiments, a conformal or non-conformal barrier layer conductor (41′, 41″) may be provided over the Schottky forming conductor (40′) and a thicker overlying gate conductor (442, 272) provided over the barrier layer conductor (41′, 41″). |
US08319308B2 |
Semiconductor device and method for manufacturing of the same
The present invention provides a semiconductor device including: a base substrate; a first semiconductor layer disposed on the base substrate; first ohmic electrodes disposed on a central region of the first semiconductor layer; a second ohmic electrode having a ring shape surrounding the first ohmic electrodes, on edge regions of the first semiconductor layer; a second semiconductor layer interposed between the first ohmic electrodes and the first semiconductor layer; and a Schottky electrode part which covers the first ohmic electrodes on the central regions, and is spaced apart from the second ohmic electrode. |
US08319305B2 |
Solid-state image sensing apparatus
This invention provides a solid-state image sensing apparatus in which a sensor portion that performs photo-electric conversion and plural layers of wiring lines including a signal line for the sensor portion are formed on a semiconductor substrate; which includes an effective pixel portion configured such that light enters the sensor portion, and an optical black portion shielded so that the light does not enter the sensor portion; and which has a light-receiving surface on the back surface side of the semiconductor substrate. The optical black portion includes the sensor portion, a first light-shielding film formed closer to the back surface side of the semiconductor substrate than the sensor portion, and a second light-shielding film formed closer to the front surface side of the semiconductor substrate than the sensor portion. |
US08319300B2 |
Solution composition for forming oxide thin film and electronic device including the oxide thin film
A solution composition for forming an oxide thin film may include a first compound including zinc, a second compound including indium, and a third compound including magnesium or hafnium, and an electronic device may include an oxide semiconductor including zinc, indium, and magnesium. The zinc and hafnium may be included at an atomic ratio of about 1:0.01 to about 1:1. |
US08319299B2 |
Thin film transistor compositions, and methods relating thereto
A process for forming at least one transistor on a substrate is described. The substrate comprises a polyimide and a nanoscopic filler. The polyimide is derived substantially or wholly from rigid rod monomers and the nanoscopic filler has an aspect ratio of at least 3:1. The substrates of the present disclosure are particularly well suited for thin film transistor applications, due at least in part to high resistance to hygroscopic expansion and relatively high levels of thermal and dimensional stability. |
US08319294B2 |
Techniques for providing a source line plane
Techniques for providing a source line plane are disclosed. In one particular exemplary embodiment, the techniques may be realized as an apparatus for providing a source line plane. The apparatus may comprise a source line plane coupled to at least one constant voltage source. The apparatus may also comprise a plurality of memory cells arranged in an array of rows and columns, each memory cell including one or more memory transistors. Each of the one or more memory transistors may comprise a first region coupled to the source line plane, a second region coupled to a bit line, a body region disposed between the first region and the second region, wherein the body region may be electrically floating, and a gate coupled to a word line and spaced apart from, and capacitively coupled to, the body region. |
US08319292B2 |
Semiconductor device
A semiconductor device includes a first MISFET and a second MISFET which are formed over a semiconductor substrate and have the same conductive type. The first MISFET has a first gate insulating film arranged over the semiconductor substrate, a first gate electrode arranged over the first gate insulating film, and a first source region and a first drain region. The second MISFET has a second gate insulating film arranged over the semiconductor substrate, a second gate electrode arranged over the second gate insulating film, and a second source region and a second drain region. The first and the second gate electrode are electrically coupled, the first and the second source region are electrically coupled, and the first and the second drain region are electrically coupled. Accordingly, the first and the second MISFET are coupled in parallel. In addition, threshold voltages are different between the first and the second MISFET. |
US08319288B2 |
Semiconductor device
The CMOS inverter coupled circuit is composed of CMOS inverters using SGTs and series-connected in two or more stages. Multiple CMOS inverters share source diffusion layers on a substrate. The CMOS inverters different in the structure of a contact formed on gate wires are alternately arranged next to each other. The CMOS inverters are provided at the minimum intervals. The output terminal of a CMOS inverter is connected to the wiring layer of the next-stage CMOS inverter via the contact of the next-stage CMOS inverter. |
US08319285B2 |
Silicon-on-insulator chip having multiple crystal orientations
A silicon-on-insulator device having multiple crystal orientations is disclosed. In one embodiment, the silicon-on-insulator device includes a substrate layer, an insulating layer disposed on the substrate layer, a first silicon layer, and a strained silicon layer. The first silicon layer has a first crystal orientation and is disposed on a portion of the insulating layer, and the strained silicon layer is disposed on another portion of the insulating layer and has a crystal orientation different from the first crystal orientation. |
US08319283B2 |
Laterally diffused metal oxide semiconductor (LDMOS) device with multiple gates and doped regions
A semiconductor device includes a source region within a semiconductor substrate, a drain region within the semiconductor substrate, a control gate over the semiconductor substrate and between the source region and the drain region, a first gate between the control gate and the drain region, and a first doped region within the semiconductor region and between the control gate and the first gate. The method of forming the semiconductor device may include depositing an electrode material over the semiconductor substrate, patterning the electrode material to form a control gate and a first gate, implanting a first doped region within the semiconductor substrate between the control gate and the first gate while using the control gate and the first gate as a mask, and implanting a source region within the semiconductor substrate. |
US08319282B2 |
High-voltage bipolar transistor with trench field plate
A bipolar transistor structure includes an epitaxial layer on a semiconductor substrate, a bipolar transistor device formed in the epitaxial layer and a trench structure formed in the epitaxial layer adjacent at least two opposing lateral sides of the bipolar transistor device. The trench structure includes a field plate spaced apart from the epitaxial layer by an insulating material. The bipolar transistor structure further includes a base contact connected to a base of the bipolar transistor device, an emitter contact connected to an emitter of the bipolar transistor device and isolated from the base contact and an electrical connection between the emitter contact and the field plate. |
US08319277B2 |
Semiconductor device, method of manufacturing same, and apparatus for designing same
A semiconductor device that includes multiple logic circuit cells having respective logic circuits formed therein and multiple interconnects connected to the corresponding logic circuit cells. At least one of the interconnects has an opening formed therein so as to have an opening ratio different from one or more of the opening ratios of the remaining interconnects. |
US08319276B2 |
Non-volatile semiconductor memory devices having charge trap layers between word lines and active regions thereof
A non-volatile memory device includes: word line disposed on a substrate; an active region crossing over the word line; and a charge trap layer that is between the word line and the active region. |
US08319275B2 |
Integrated circuit memory devices having selection transistors with nonuniform threshold voltage characteristics
Provided is a semiconductor memory device. In the semiconductor memory device, a lower selection gate controls a first channel region that is defined at a semiconductor substrate and a second channel region that is defined at the lower portion of an active pattern disposed on the semiconductor substrate. The first threshold voltage of the first channel region is different from the second threshold voltage of the second channel region. |
US08319274B2 |
Semiconductor device
A gate dielectric functioning as a charge-trapping layer of a non-volatile memory cell with a structure of an insulator gate field effect transistor is formed by laminating a first insulator formed of a silicon oxide film, a second insulator formed of a silicon nitride film, a third insulator formed of a silicon nitride film containing oxygen, and a fourth insulator formed of a silicon oxide film in this order on a main surface of a semiconductor substrate. Holes are injected into the charge-trapping layer from a gate electrode side. Accordingly, since the operations can be achieved without the penetration of the holes through the interface in contact to the channel and the first insulator, the deterioration in rewriting endurance and the charge-trapping characteristics due to the deterioration of the first insulator does not occur, and highly efficient rewriting (writing and erasing) characteristics and stable charge-trapping characteristics can be achieved. |
US08319273B2 |
Self-aligned charge storage region formation for semiconductor device
Devices and methods for forming self-aligned charge storage regions are disclosed. In one embodiment, a method for manufacturing a semiconductor device comprises forming a layer of a nitride film stacked between two oxide films on a semiconductor substrate, and forming a gate electrode on the layer of the nitride film stacked between the two oxide films. In addition, the method comprises removing side portions of the nitride film such that a central portion of the nitride film below a center portion of the gate electrode remains, oxidizing the central portion of the nitride film, and forming charge storage layers in the side portions of the nitride film, where the charge storage layers are separated by the central portion of the nitride film. |
US08319270B2 |
Semiconductor device and method for manufacturing the same
A non-volatile memory of a semiconductor device has a tunnel insulation film provided on the active area; a floating gate electrode provided on the tunnel insulation film; a control gate electrode provided over the floating gate electrode; and an inter-electrode insulation film provided between the floating gate electrode and the control gate electrode, wherein, in a section of the non-volatile memory cell in a channel width direction, a dimension of a top face of the active area in the channel width direction is equal to or less than a dimension of a top face of the tunnel insulation film in the channel width direction, and the dimension of the top face of the tunnel insulation film in the channel width direction is less than a dimension of a bottom face of the floating gate electrode in the channel width direction. |
US08319263B2 |
Magnetic tunnel junction device
The output voltage of an MRAM is increased by means of an Fe(001)/MgO(001)/Fe(001) MTJ device, which is formed by microfabrication of a sample prepared by the following steps. A single-crystalline MgO (001) substrate 11 is prepared. An epitaxial Fe(001) lower electrode (a first electrode) 17 with the thickness of 50 nm is grown on a MgO(001) seed layer 15 at room temperature, followed by annealing under ultrahigh vacuum (2×10−8 Pa) and at 350° C. A MgO(001) barrier layer 21 with the thickness of 2 nm is epitaxially formed on the Fe(001) lower electrode (the first electrode) at room temperature, using a MgO electron-beam evaporation. A Fe(001) upper electrode (a second electrode) with the thickness of 10 nm is then formed on the MgO(001) barrier layer 21 at room temperature. This is successively followed by the deposition of a Co layer 21 with the thickness of 10 nm on the Fe(001) upper electrode (the second electrode) 23. The Co layer 21 is provided so as to increase the coercive force of the upper electrode 23 in order to realize an antiparallel magnetization alignment. |
US08319259B2 |
Semiconductor power switch having nanowires
A semiconductor power switch and method is disclosed. In one Embodiment, the semiconductor power switch has a source contact, a drain contact, a semiconductor structure which is provided between the source contact and the drain contact, and a gate which can be used to control a current flow through the semiconductor structure between the source contact and the drain contact. The semiconductor structure has a plurality of nanowires which are connected in parallel and are arranged in such a manner that each nanowire forms an electrical connection between the source contact and the drain contact. |
US08319255B2 |
Low side Zener reference voltage extended drain SCR clamps
In an ultra high voltage lateral DMOS-type device (UHV LDMOS device), a central pad that defines the drain region is surrounded by a racetrack-shaped source region with striations of alternating n-type and p-type material radiating outwardly from the pad to the source to provide for an adjustable snapback voltage. |
US08319253B2 |
Semiconductor light-emitting device
The device including an active layer composed of AlGaInP, and an n-type clad layer and a p-type clad layer disposed so as to sandwich the active layer, the n-type clad layer and the p-type clad layer each having a bandgap greater than the bandgap of the active layer. The n-type clad layer includes a first n-type clad layer composed of AlGaInP and a second n-type clad layer composed of AlInP; and the second n-type clad layer has a thickness in the range from 40 nm to 200 nm. |
US08319252B2 |
Light emitting device with high color rendering index and high luminescence efficiency
A light emitting device comprises two light-emitting diode (LED) groups, a group of luminophor layers, and an input terminal. The first LED group includes at least one blue LED emitting light having a dominant wavelength in a range between 400 nm and 480 nm, and the second LED group includes at least one red-orange LED emitting light having a dominant wavelength in a range between 610 nm and 630 nm. The group of luminophor layers, which are selected from one of silicates, nitrides, and nitrogen oxides, are positioned above the first LED group and partially converts the light emitted by the first LED group into light having a dominant wavelength in a range between 500 nm and 555 nm. The input terminal is connected to the two LED groups for providing desired electric energy thereto. |
US08319249B2 |
Semiconductor light emitting device
A semiconductor light emitting device and corresponding method of manufacture, where the semiconductor light emitting device includes a light emitting structure, a second electrode layer, an insulating layer, and a protrusion. The light emitting structure comprises a second conductive semiconductor layer, an active layer under the second conductive semiconductor layer, and a first conductive semiconductor layer under the active layer. The second electrode layer is formed on the light emitting structure. The insulating layer is formed along the circumference of the top surface of the light emitting structure. The protrusion protrudes from the undersurface of the insulating layer to the upper part of the first conductive semiconductor layer. |
US08319244B2 |
Semiconductor light emitting device
Discussed is a semiconductor light emitting device. The semiconductor light emitting device includes a first conductive semiconductor layer, an active layer under the first conductive semiconductor layer, a second conductive semiconductor layer under the active layer, a second electrode layer under the second conductive semiconductor layer, and a transmissive conductive layer at least one part between the second conductive semiconductor layer and the second electrode layer. |
US08319243B2 |
Nitride semiconductor light-emitting device and method of manufacturing the same
A nitride semiconductor light-emitting device including a reflecting layer made of a dielectric material, a transparent conductive layer, a p-type nitride semiconductor layer, a light emitting layer and an n-type nitride semiconductor layer in this order and a method of manufacturing the same are provided. The transparent conductive layer is preferably made of a conductive metal oxide or an n-type nitride semiconductor, and the reflecting layer made of a dielectric material preferably has a multilayer structure obtained by alternately stacking a layer made of a dielectric material having a high refractive index and a layer made of a dielectric material having a low refractive index. |
US08319242B2 |
Light-emitting semiconductor device, mounted substrate, and fabrication method thereof
A light-emitting semiconductor device includes a lead frame having lead electrodes, a reflector arranged with the lead frame, and a light-emitting semiconductor chip accommodated in the reflector and having electrodes connected to the lead electrodes by a flip-chip bonding method, wherein: a gap between the lead frame and the light-emitting semiconductor chip is filled with a cured underfill material, and a cured silicon oxide film of 0.05 to 10 μm thickness is formed covering surfaces of the light-emitting semiconductor chip and reflector. |
US08319240B2 |
Light-emitting device
To provide a light-emitting device mounting a light-emitting element having a metal film on the rear side surface, which is excellent in light extraction efficiency since it has high heat dissipating properties and high light reflection efficiency, and which can suppress the reduction of light extraction efficiency due to the deterioration with time.A light-emitting device which comprises: a substrate made of an inorganic insulating material, a metal conductor layer formed on the mounting portion of the substrate, a conductive protective layer formed on the above metal conductor layer, a light-emitting element having a metal film on the rear side surface, and mounted on the mounting portion of the above substrate so that the metal film faces the conductive protective layer and is located inside the edge of the conductive protective layer, an electroconductive bonding material to bond the light-emitting element with the conductive protective layer, a reflection film formed on the mounting surface of the above substrate in such a shape as to exclude the conductive protective layer and the vicinity around it, and an insulating protective layer formed on the mounting surface of the substrate so as to cover the entirety of the above reflection film including its edge. |
US08319234B2 |
Organic light emitting diode display having a multi-color pixel including a hydrophobic layer
An organic light emitting diode display and a fabrication method thereof, the display including a substrate; a thin film transistor on the substrate; and an organic light emitting diode on the substrate, the organic light emitting diode including a pixel electrode, an organic emission layer, and a common electrode, wherein the organic emission layer includes a red (R) pixel, a green (G) pixel, and a blue (B) pixel, the pixel electrode includes a first pixel electrode, a second pixel electrode, and a third pixel electrode that respectively correspond to the red pixel, the green pixel, and the blue pixel, the first pixel electrode, the second pixel electrode, and the third pixel electrode each have different thicknesses, and the first pixel electrode, the second pixel electrode, and the third pixel electrode each include a first hydrophobic layer. |
US08319233B2 |
Light emitting device
Disclosed is a light emitting device including a substrate, a light emitting structure arranged on the substrate, the light emitting structure including a first semiconductor layer, a second semiconductor layer and an active layer arranged between the first semiconductor layer and the second semiconductor layer, a first electrode electrically connected to the first semiconductor layer, and a second electrode electrically connected to the second semiconductor layer, wherein the light emitting structure has a top surface including a first side and a second side which face each other, and a third side and a fourth side which face each other. |
US08319232B2 |
Method for providing and removing discharging interconnect for chip-on-glass output leads and structures thereof
Microelectronic devices may be fabricated while being protected from damage by electrostatic discharge. In one embodiment, a shorting circuit is connected to elements of the microelectronic device, where the microelectronic device is part of a chip-on-glass system. In one aspect of this embodiment, a portion of the shorting circuit is in an area of a substrate where a microchip is bonded. In another embodiment, shorting links of the shorting circuit are comprised of a fusible material, where the fusible material may be disabled by an electrical current capable of fusing the shorting links. |
US08319228B2 |
Resin composition for optical semiconductor device, optical-semiconductor-device lead frame obtained using the same, and optical semiconductor device
The present invention relates to a resin composition for optical semiconductor devices, the resin composition including the following ingredients (A) to (D): (A) an epoxy resin; (B) a curing agent; (C) a polyorganosiloxane; and (D) a white pigment. |
US08319227B2 |
Light emitting device
A light emitting device (LED) is provided. The LED comprises a first conductivity type semiconductor layer, an active layer, and a second conductivity type semiconductor layer. The active layer is on the first conductivity type semiconductor layer. The second conductivity type semiconductor layer is on at least one side of the active layer and the first conductivity type semiconductor layer, and on the active layer. |
US08319223B2 |
Thin film transistor array panel using organic semiconductor and a method for manufacturing the same
The present invention disclosed an organic thin film transistor, an organic thin film transistor array substrate and an organic thin film transistor display. The present invention disclosed organic materials which is proper for the application to a large screen display. The presentation also disclosed structures and a method for manufacturing such an organic thin film transistor, the organic thin film transistor array substrate and the organic thin film transistor display. |
US08319220B2 |
Array substrate for liquid crystal display device and method of fabricating the same
A method of fabricating a liquid crystal display device includes: a first step of attaching a polarizing plate to an outer surface of a liquid crystal panel; a second step of attaching a tape carrier package (TCP) to the liquid crystal panel; a third step of coating a resin onto a rear surface of the TCP and a connection portion of the liquid crystal panel and the TCP; a fourth step of inspecting the TCP and the liquid crystal display panel; a fifth step of inserting the liquid crystal panel into a transferring means; a sixth step of transferring the transferring means; a seventh step of extracting the liquid crystal panel from the transferring means; a eighth step of attaching the TCP to a printed circuit board (PCB); a ninth step of inspecting the PCB, the TCP and the liquid crystal panel; and a tenth step of assembling the liquid crystal panel and a backlight unit with a plurality of frames. |
US08319210B2 |
Light-emitting element, light-emitting device, and electronic device
A light-emitting element disclosed in the present invention includes a light-emitting layer and a first layer between a first electrode and a second electrode, in which the first layer is provided between the light-emitting layer and the first electrode. The present invention is characterized by the device structure in which the first layer comprising a hole-transporting material is doped with a hole-blocking material or an organic compound having a large dipole moment. This structure allows the formation of a high performance light-emitting element with high luminous efficiency and long lifetime. The device structure of the present invention facilitates the control of the rate of the carrier transport, and thus, leads to the formation of a light-emitting element with a well-controlled carrier balance, which contributes to the excellent characteristics of the light-emitting element of the present invention. |
US08319204B2 |
Semiconductor device
A recording layer 52 made of a chalcogenide material which stores a high-resistance state of a high electrical resistance value and a low-resistance state of a low electrical resistance value is used as a memory element RM in a memory cell region, and it is formed so that a concentration of Ga or In of a first layer 52a positioned on a lower electrode TP side of the recording layer 52 is higher than the corresponding concentration of a second layer 52b positioned on an upper electrode 53 side. For example, the recording layer is formed so that a content of Ga or In of the second layer is 5 atomic % or more smaller than that of the first layer. Also, a circuit which can reverse the voltage polarity between the upper electrode and the lower electrode in a set operation and a reset operation is provided. |
US08319203B2 |
Phase change material, a phase change random access memory device including the phase change material, and a semiconductor structure including the phase change material
Methods of forming a phase change material are disclosed. The method includes forming a chalcogenide compound on a substrate and simultaneously applying a bias voltage to the substrate to alter the stoichiometry of the chalcogenide compound. In another embodiment, the method includes positioning a substrate and a deposition target having a first stoichiometry in a deposition chamber. A plasma is generated in the deposition chamber to form a phase change material on the substrate. The phase change material has a stoichiometry similar to the first stoichiometry. A bias voltage is applied to the substrate to convert the stoichiometry of the phase change material to a second stoichiometry. A phase change material, a phase change random access memory device, and a semiconductor structure are also disclosed. |
US08319201B2 |
Laser produced plasma EUV light source having a droplet stream produced using a modulated disturbance wave
A plasma generating system is disclosed having a source of target material droplets, e.g. tin droplets, and a laser, e.g. a pulsed CO2 laser, producing a beam irradiating the droplets at an irradiation region, the plasma producing EUV radiation. For the device, the droplet source may comprise a fluid exiting an orifice and a sub-system producing a disturbance in the fluid which generates droplets having differing initial velocities causing at least some adjacent droplet pairs to coalesce together prior to reaching the irradiation region. In one implementation, the disturbance may comprise a frequency modulated disturbance waveform and in another implementation, the disturbance may comprise an amplitude modulated disturbance waveform. |
US08319199B2 |
Irradiation sources and methods
Irradiating assemblies can have a housing with a reflector extending linearly parallel to a lamp. Radiation can be emitted from one opening, for example in a bottom portion of the housing, as well as from another opening, for example a side opening in the housing. Irradiating assemblies can also have first and second reflector portions at angles with respect to each other wherein radiation is reflected out of a housing that does not have an end reflector. Irradiating assemblies can be configured to have cooling flow openings in side walls so that cooling fluid such as air can flow between the side walls and adjacent surfaces of a reflector. Irradiating assemblies can incorporate lamps having first and second electrodes wherein the first and second electrodes are oriented at an angle with respect to each other. Methods of irradiating material may include irradiating a surface with emissions from a first portion of an assembly and irradiating a surface with emissions from a second portion of an assembly different from the first portion. |
US08319198B2 |
Device and method for determining control parameters for an irradiation unit, irradiation unit and irradiation method
The invention concerns a device for determining control parameters for an irradiation system by means of which a number of irradiation doses are successively deposited at different target points in a target volume. The device comprises an input device which is designed for detecting a target region and for detecting a movement of the target region, an evaluation device for detecting control parameters for controlling a beam in such a way that with the help of the control parameters a beam is able to follow the movement of the target region and to deposit a defined dose distribution in the target region, wherein the evaluation device is designed in such a way that when detecting the control parameters at least a first selectable control parameter is detected so that the beam is able to follow the movement of the target region merely orthogonally to beam direction, or when detecting the control parameters, at least a first selectable control parameter and a further control parameter representing energy modulation are detected, wherein the determination of the at least first control parameter and the further control parameter is performed by considering motion tracking in beam direction. |
US08319197B2 |
Frequency adjusting apparatus
A wafer having a plurality of elements closely arranged thereon is irradiated with an ion beam while being conveyed in one direction by a conveying unit. Each of shutters adjusts an irradiation time during which a target area of the wafer is irradiated with the ion beam. Thus, a frequency in the target area is adjusted. Each of a plurality of mask holes in a pattern mask disposed between the wafer and the shutters corresponds to one area of the wafer. The mask holes are alternately displaced in a wafer conveying direction in which the wafer is conveyed, and are arranged in a plurality of columns perpendicular to the wafer conveying direction. To individually open and close the mask holes, the shutters are arranged to correspond to the respective mask holes. Thus, frequency adjustment, for areas in one column perpendicular to the wafer conveying direction, is performed in multiple steps. |
US08319193B2 |
Charged particle beam apparatus, and method of controlling the same
Provided is a charged particle beam apparatus, which can emit a stable electron beam, having high brightness and a narrow energy width. The charged particle beam apparatus comprises a field emission electron source, electrodes for applying an electric field to the field emission electron source, and a vacuum exhaust unit for keeping the pressure around the field emission electron source at 1 10−8 Pa or less. The apparatus is so constituted as to use such one of the electron beams emitted as has an electron-beam-center radiation angle of 1×10−2sr or less, and to use the electric current thereof, the second order differentiation of which is negative or zero with respect to the time, and which reduces at a rate of 10% or less per hour. The charged particle beam apparatus further comprises a heating unit for the field emission electron source, and a detection unit for the electric current of the electron beam. The field emission electron source is repeatedly heated to keep the electric current of the electron beam to be emitted, at a predetermined value or higher. |
US08319192B2 |
Charged particle apparatus
An electromagnetic compound objective lens is provided for charged particle device, especially as an objective lens of low-voltage scanning electron microscope (LVSEM), which comprises a magnetic immersion lens and an electrostatic immersion lens. The magnetic immersion lens orients its gap between an inner pole piece and an outer pole piece to specimen's surface, and uses a magnetic specimen stage. The electrostatic immersion lens comprises three or four electrodes which apply suitable retarding field to a primary beam of the charged particle device for reducing its landing energy on specimen surface and further eliminating imaging aberrations. |
US08319191B2 |
Sensor devices and related methods
Embodiments of sensor systems and related methods of operating and manufacturing the same are described herein. The sensor systems can be used to detect atomic or subatomic particles or radiation. Other embodiments and related methods are also disclosed herein. |
US08319182B1 |
Methods and systems for using IR spectroscopy to quantify degradation of wiring insulation
A system for the measurement of degradation of electrical wire insulation is described. The system includes an infrared (IR) spectrometer, a fiber optic cable having a first end and a second end, where the first end is configured to interface to the IR spectrometer, and a clamping device for engaging the electrical wire to be tested for insulation degradation. The second end of said fiber optic cable is mounted within the clamping device such that the second end is adjacent the wire insulation. |
US08319174B2 |
Scanned writing of an exposure pattern on a substrate having a spot size modulator and dual motor for moving the substrate table and a laser spot relative to each other
An exposure pattern is written on a substrate, by scanning a light spot along a trajectory over the substrate and switching it on and off according to a desired pattern. Respective spot sizes of the light for illuminating the substrate in respective parts of the trajectory according to a geometry of the pattern. Respective pitch values between successive ones of the parts of the trajectory are selected, in relation to the spot size selected for the respective parts. The light spot is scanned over the substrate along the trajectory, with the selected pitch values between the trajectory parts and a position dependent spot size along the trajectory. In an embodiment a helical trajectory is used. |
US08319172B2 |
Optoelectronic sensor with alignment light transmitter
An optoelectronic sensor (10) is provided having a transmitter (12) for operating light, a light receiver (14) for the generation of an electrical received signal from incident light and an evaluation unit (16) which can detect an object in the beam path from the transmitter (12) for operating light to the light receiver (14) from the received light, wherein a first alignment light transmitter (13a) is provided. In this respect, a second alignment transmitter (13b) is provided, with the first alignment light transmitter (13a) and the second alignment light transmitter (13b) being able to be individually activated and the evaluation unit (16) being designed to determine alignment information on the adjustment of the sensor (10) from a received first alignment signal of the light receiver (14) with an activated first alignment light transmitter (13a) and from a received second alignment signal of the light receiver (14) with an activated second alignment light transmitter (13b). |
US08319171B2 |
Optical scanning type photoelectric switch
There is provided an optical scanning type photoelectric switch capable of facilitating control of holding a set detection sensitivity, wherein first and second reflection surfaces with different reflection factors are built as reference objects in the optical scanning type photoelectric switch, and arranged in a measurement invalid range in rotation of a scanning mirror, a light projection path, a light reception path, a laser light source LD and a light receiving element, which are used for scanning in the measurement area, are shared, and when a light reception intensity of the white second reflection surface is smaller than a “reference light reception intensity (white)”, a light projection driving section is controlled to increase the light projection intensity. |
US08319170B2 |
Method for adapting a pulse power mode of a proximity sensor
There is described portable electronic devices having one or more proximity sensors with adaptive capabilities that can help reduce power consumption. The proximity sensors of the portable electronic device in accordance with the present invention may be adjusted to operate in multiple and/or different modes. These modes are environmentally and contextually driven. An adaptive sensor is dynamically adjusted based on different criteria. In particular, adjustments are based on correlations of input signals from one or more sensors of the device, data signals received from the device's processor and/or external data signals received from an external source, which provide characterization values of environmental, contextual and/or ambient light characteristics. Adjustments are made to pulse power to affect the range of the sensor, pulse frequency, filtering of noise of the sensor input signal to attenuate interference and the spectrum of a proximity detector. |
US08319168B2 |
Semiconductor image sensor array device, apparatus comprising such a device and method for operating such device
A plural line CMOS sensor array device is provided with sensor cells arranged in a matrix of coordinate-wise rows and columns. Each cell comprises a photosensitive area, an output node, and a transfer gate for selectively interconnecting the photosensitive area and the output node. Along at least a first coordinate direction adjacent cells are functionally configured as mutually mirror-symmetric structures in that their proximate output nodes are facing each other and are arranged for separately feeding a respective output channel. Preferably, also in a second coordinate direction adjacent cells are functionally configured as mutually mirror-symmetric structures in that their proximate output nodes are facing each other and all such facing output nodes are separately feeding a respective column-directed output channel. |
US08319166B2 |
Solid-state image pick-up device and pixel signal readout method having dual potential well, dual transfer gate electrode and dual floating-diffusion region for separately transferring and storing charges respectively
A solid-state image pick-up device and a method of reading out a pixel signal thereof are provided, and the solid-state image pick-up device provides a large dynamic range without an increase in the area of a pixel. Plural pixels are arranged therein. Each pixel includes a first potential well PW1 for storing charges generated by light; a charge-distributing-potential barrier CDB adjacent to the first potential well PW1; a second potential well PW2 opposite to the first potential well PW1 with respect to the charge-distributing-potential barrier, the second potential well PW2 storing charges generated by light of an identical intensity, the charges stored in the second potential well PW2 being less than the charges stored in the first potential well PW1; first and second transfer gate electrodes 31 and 32 for transferring the charges stored in the first and second potential wells PW1 and PW2, respectively; and first and second floating-diffusion regions 26 and 27 for separately storing the charges transferred by the first and second transfer gate electrodes 31 and 32, respectively. |
US08319164B2 |
Rolling projectile with extending and retracting canards
A slow rolling projectile comprises a projectile body has a forward section and a rear section and having a longitudinal axis. Two or more canards in the forward section are capable of being extended from and retracted into the projectile body at predetermined frequencies and/or for predetermined times. Two or more tail fins in the rear section are fixed coextensive to or at an angle to the longitudinal axis, and an actuator extends and retracts the canards. The canards are capable of being extended and retracted at a rate based on the rotation of the projectile sufficient to correct for lateral movement. A GPS or INS navigational system activates an actuator to extend and retract the canards. |
US08319163B2 |
Roll isolation bearing
A GNC device for use with a projectile, includes a rotating GNC portion and a non-rotating GNC portion, the rotating GNC portion being fixedly coupled to a projectile body, at least one bearing being interposed between the rotating GNC portion and a non-rotating GNC portion, the at least one bearing permitting the rotating GNC portion to rotate with respect to the non-rotating GNC portion. In a GNC device for use with a projectile, a method is further included. |
US08319161B2 |
Method and device for uniformly heating a sample by microwave radiation
The present invention concerns a method and a device for uniformly heating a sample by microwave radiation. According to the invention, at least one stirring element is immersed at least partly in a sample to be heated, said stirring element comprising a magnetic or magnetisable material. A rotating or oscillating magnetic field interacting with said stirring element is generated in a cavity adapted to receive the sample to be heated in order to impart a rotational or translational movement to said stirring element. The rotational or translational movement of said stirring element is contactlessly detected while applying microwave radiation to said sample. |
US08319159B2 |
Radiant panel of anodized aluminium with electric resistance of stainless steel
A panel for electric heating, with an outer hermetic aluminum shell, an inner shell with a rectangular base and a cover, inside which is an ohmic resistance in the shape of a planar serpentine, formed of a series of U-bends and having two pseudo-circular endings that extend to the inside of a hermetic contact module integrated with the outer shell, wherein the serpentine is made of a rigid bar having a rectangular section, wherein the base of the inner shell incorporates a thick layer of oxide that favors infrared irradiation, and wherein an internal thermal insulator hinders the flow of heat towards the cover. |
US08319154B2 |
Self-heating fluid container
A self-heating fluid connector comprising a housing in which is provided exothermic phase change material and one or more fluid channels extending from one end of the housing to the other, in thermal communication with the exothermic phase change material, whereby fluid passing through the fluid conduits is heated by the exothermic phase change material. The self-heating connector is particularly suited for use with a fluid container and a fluid delivery port such as a baby's bottle and feeding teat. |
US08319151B2 |
Method to manufacture a hearing aid with indirect laser exposure
To further automate the manufacture of hearing aid component parts that are in part produced with a rapid prototyping method, a laser beam for curing material is generated by a laser, and a workpiece support that can be directly exposed by the laser is provided. The laser beam is deflected by an optic device so that the workpiece support can be indirectly exposed with the laser. Material can thereby be more easily applied in undercuts of workpiece blanks that form the basis of the hearing aid component parts. |
US08319148B2 |
System and method of dual laser beam welding of first and second filler metals
A system and method for laser beam welding at least two adjacent superalloy components involves substantially simultaneous formation of a base weld with a first filler metal placed between the components and cap weld with second filler metal formed over the base weld. A shim is inserted between the components, which may optionally be formed with a groove along the joint surface. A filler wire is fed to a location over the given surface or within the optional groove. Two lasers or a laser and coupled beam splitter supply first and second laser beams that are applied at focal points separated by a predetermined distance (e.g., 0.05-1.5 cm). The first laser beam is used to form a base weld with the first filler metal between the components, and the second laser beam is used to form a cap weld with the second filler metal on top of the base weld. |
US08319140B2 |
Spot welding gun for resistance welding of workpieces
A spot welding gun for resistance welding of workpieces, includes a base body and a bracket, in which electrode holders are arranged, the electrodes being in turn arranged in the holders. At least one electrode holder is fixed to an actuator that enables the electrode holder fixed thereto with the electrode to be displaced in longitudinal direction towards other electrodes. To protect the electrodes, a winding device with a band is arranged, the band being displaceably arranged between the contact surface of the electrode and the workpiece opposite the electrode. The winding device assigned to the displaceable electrode is connected to the displaceable electrode so that it moves at the same time as the electrode when the electrode is moved in longitudinal direction. The electrode holders and the electrodes have devices for guiding the band from the winding device axially along the electrode holders towards the electrode and vice versa. |
US08319138B2 |
Inert gas tube and contact tube of an apparatus for improved narrow-gap welding
An apparatus for improved narrow-gap welding is provided. The apparatus includes an inert gas tube within which a contact tube is arranged, the contact tube includes a wire feed for a melting wire. The end of the inert gas tube is ceramic. In another embodiment, the inert gas tube of the apparatus includes a plurality of materials with a high thermal conductivity. A first metallic material at the end of the inert gas tube has a higher thermal conductivity than a second material at a start of the inert gas tube. The first metallic material is molybdenum, tungsten, an alloy of molybdenum or tungsten, or copper or a copper alloy. |
US08319137B2 |
Vacuum switch tube
The present invention relates to a vacuum switch tube, which includes a first contact and a second contact disposed on conductive rods respectively. The two contacts are disposed facing each other. The two contacts are cylinders and include conductive members and magnetic members to form contact bodies. The cross section shape of the magnetic members is divided by a neutrality line into two unequal regions. The magnetic member of the first contact and the conductive member of the second contact are disposed corresponding to each other. The conductive member of the first contact and the magnetic member of the second contact are disposed corresponding to each other. The two vacuum switch contacts are anti-symmetrically disposed, such that a rotating magnetic field having rotating lines of magnetic force is formed, so that re-ignition possibility during voltage breaking is effectively reduced, and an arc voltage is decreased. |
US08319134B2 |
Electrosurgical pencil switch, circuitry, and method of assembly
Formation of an assemblage of electrically conductive components for a new electrosurgical pencil is disclosed, and assembly of those components in a method for automating the manufacture and combination of current carrying metal circuitry and operable switching components in “electrosurgical pencils” which supply current to an active terminal, for application of high frequency or high power electrical current to a surgical site, and control of such current through coaction of the elements of the switch. In manufacture, the design of the switch components allows start-to-finish automated assembly of the switch, whereby an array of identical multiple metal “frames” may be formed from a reel, then each frame separated and enclosed within molded plastic, and the resulting cabinet joined with a housing to create an inexpensive hand piece, for use with a high quality, reusable cable and plug assembly. |
US08319132B2 |
Load-break switch
A load interrupter, especially to be mounted on a busbar includes a housing and a cover that is hinged thereto, a snap switch mechanism for establishing or interrupting an electrical connection between corresponding contacts. A control lever for switching between a current-carrying operation and a current interrupting operation, and a control mechanism which, depending on the position of the control lever, releases or blocks a release element for a displacement. The release element being coupled to a locking device which is arranged in such a manner that it can be engaged with or disengaged from the cover. |
US08319128B2 |
System and methods for electronic device keyboard illumination
A keyboard may be generally illuminated while also providing for key-specific illumination of one or more particular keys. The keyboard may be generally illuminated using any configuration of any number of suitable illumination sources. The keyboard may selectively illuminate any key or keys together with or apart from the general illumination of other keys. The keyboard may also variably illuminate certain keys to aid the user in navigating the keyboard. |
US08319118B2 |
Optical transceiver providing independent spaces for electrical components and for optical components
An optical transceiver that reduces the EMI noise leaked therefrom is reduced is disclosed. The optical transceiver of the invention provides a metal housing, an optical subassembly, and an electronic circuit. The metal housing includes a first space that installs the electronic circuit and a second space that installs the optical subassembly. The first space and the second space are electrically shielded to each other, in addition that both spaces are shielded from the external. In the optical transceiver of the invention, even the second space provides the optical path to the optical connector, which becomes a definite leak path for the EMI noise, the leakage from the first space to the external through the optical path is prevented. |
US08319116B2 |
Rib reinforcement of plated thru-holes
Systems and methods for providing mechanically reinforced plated through-holes (PTH) in PCBs, which advantageously allow improved soldering capabilities and reliability, are described herein. Such systems and methods are achieved by reducing the heat sinking effects of PTHs by providing one or more vias surrounding the PTHs to provide an electrical connection between the PTH and the internal and bottom conductive layers of a PCB. In this regard, the PTHs are spaced apart from at least one of the internal conductive layers (e.g., ground or power layers), so the heat sinking effects are reduced. This feature enables molten solder to substantially fill the entire PTH before freezing, thereby improving the mechanical and electrical connection between an electrical component and the PCB. One or more electrically-nonfunctional lands (or “rib reinforcements”) are provided in internal conductive layers to mechanically support the walls of the PCB. These rib reinforcements improve the mechanical strength of the PTHs without affecting the electrical performance and without impacting the ability to solder components to the PCB. |
US08319115B2 |
Wiring board and manufacturing method thereof
A wiring board includes a plurality of circular semiconductor element connection pads deposited in a lattice form onto a mounting portion of an insulation substrate, their upper surfaces being connected to electrodes of a semiconductor element. A solder resist layer is deposited onto the insulation substrate, which covers the side surfaces of these pads and exposes the upper surfaces of these pads. The solder resist layer has a concave part whose bottom surface corresponds to at least all the upper surfaces of these pads. |
US08319114B2 |
Surface mount power module dual footprint
A dual footprint mounting package for a surface mount power converter modules and its method of manufacture. Castellated regions are formed on the edge of the component package using the appropriate sized drill or milling bit. Edge plating is applied to the castellated surfaces to create edge pads. The edge plating provides electrical continuity between the edge pads and the SMT pads. Solder mask, or other materials, is applied to prevent solder from wicking between each SMT pad and its respective edge pad. Such component may be attached to a larger device PWB using either the edge pads or the SMT pads, or may even be attached using a combination of the two, such as in the event of a pad failure or other defect. |
US08319112B2 |
Environmental protection coating system and method
A circuit board assembly includes a circuit board having an outer surface, the outer surface being configured with a plurality of discrete electrical components that are each manufactured independently of one another. The circuit board assembly further includes a domed lid enclosure disposed over one of the plurality of discrete electrical components and an additional dielectric coating overlying the outer surface and the domed lid enclosure. |
US08319107B2 |
Circuit board and radiating heat system for circuit board
A circuit board and a heat radiating system of the circuit board. In the circuit board, a plurality of conductive layer regions coated with a conductor are separately formed on both sides of an insulating substrate, the conductive layer region formed on either side of an insulating region on each of the both sides of the insulating substrate, the plurality of the conductive layer regions includes a plurality of through holes which penetrate through the insulating substrate and are coated with a conductor over an inner wall, the conductor in the through hole electrically conducts the coated conductor of the plurality of the conductive layer regions, one of the lead pins is connected to one of the separated conductive layer regions on the both sides based on the insulating region, and the other lead pin is connected to the other conductive layer region. Accordingly, the efficient heat radiation of the circuit board can prevent the component malfunction, the lifespan reduction, the power consumption increase, and the illuminance drop. |
US08319100B2 |
Electronic device enclosure
An electronic device enclosure includes an enclosure body, a bezel and a connecting assembly. The enclosure body includes a front panel. The front panel includes metal. The bezel includes bamboo and covers the front panel. The connecting assembly includes a fastener and a retaining clip engaged with the fastener. The fastener is fastened to the bezel and the retaining clip is clasped in the front panel. |
US08319099B2 |
Locking device and electronic enclosure using the same
An electronic enclosure includes a base, a cover mounted on the base, a first locking module engaged on the cover, a second locking module, and a locking structure. The base defines a number of supporting recesses defined therein. The cover includes a number of barbs for matching with the supporting recesses of the base. The second locking module includes at least one locking member. The at least one locking member includes a pivot portion pivotably engaging with the base, a first end and a second end opposite to the first end. The locking structure abuts the first end of the at least one locking member to rotate the second end to engage with the first locking module, whereby the cover is fixed on the base. |
US08319094B2 |
Multilayer terionomer encapsulant layers and solar cell laminates comprising the same
The present invention provides a solar cell pre-lamination assembly comprising a terionomer multilayer film or sheet and solar cell modules prepared therefrom. |
US08319093B2 |
Photovoltaic module
A photovoltaic module includes an encapsulated photovoltaic element and an infrared transmissive decorative overlay simulating conventional roofing. |
US08319092B1 |
Nano power cell and method of use
A nano power cell and method of use are described wherein the nano power cell absorbs electromagnetic energy is nano particles in an optical fluid that flow in microchannels of the nano power cell. |
US08319089B2 |
Oscillatory, magnetically activated position sensor
This invention provides an oscillatory, magnetically-activated position sensor. Magnetic flux linkages between a magnet and an inductor having a magnetic core modulate the core permeability, and thus inductance, responsive to mechanical position. An electronic oscillator comprises the inductor as part of a tank circuit. The amplitude and frequency of the oscillator is therefore responsive to mechanical position. Circuitry for generating a sensor output signal responsive to oscillator amplitude, and thus to mechanical position is provided. Matrix operation of sensors is taught.A key position sensor for a musical instrument clavier is taught. A clavier key comprising plural inventive sensors invention is taught. A touch adjusting mechanism for a clavier key comprising inventive sensors is provided. A clavier piston comprising a sensor according to this invention is provided. A stop action magnet comprising a sensor according to this invention is provided. |
US08319085B2 |
Musical controller
Specially designed for relating musical sounds to the conventional way of writing on a staff and vice versa, the controller is formed by a casing which is flat, cylindrical or some other shape, on which a staff is depicted, with, in the areas of the staff corresponding to each of the musical notes, sensors/push-buttons corresponding to natural, flat and sharp notes (or double sharp or double flat or natural sign, if present on the frame), as well as light indicators. The notes can thus be identified aurally when working on the device as if the music was written on a staff, while if a MIDI signal is connected to the control circuit it is possible to display, in real time, on said staff and via the light indicators, each of the notes of said melody, enabling quick and easy identification of said notes. |
US08319084B2 |
Method of studying an isolated audio track from an original, multi-track recording using variable gain control
A system, method, and apparatus for learning music through an educational audio track embodied on a computer readable medium are presented. The system can comprise have components including a processor, an input device, a database, a transformation module, an emulation recording module, an integration engine, an output module, and an output device, wherein each component is operable in itself to perform it's function in the system and operable with other system components to provide a system to a user for learning music. |
US08319080B1 |
Plants and seeds of hybrid corn variety CH291635
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH291635. The invention thus relates to the plants, seeds and tissue cultures of the variety CH291635, and to methods for producing a corn plant produced by crossing a corn plant of variety CH291635 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH291635. |
US08319075B1 |
Inbred maize variety PH17RD
A novel maize variety designated PH17RD and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH17RD with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH17RD through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH17RD or a locus conversion of PH17RD with another maize variety. |
US08319072B2 |
Plants and seeds of corn variety CV556014
According to the invention, there is provided seed and plants of the corn variety designated CV556014. The invention thus relates to the plants, seeds and tissue cultures of the variety CV556014, and to methods for producing a corn plant produced by crossing a corn plant of variety CV556014 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV556014 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV556014. |
US08319070B2 |
Plants and seeds of corn variety CV385683
According to the invention, there is provided seed and plants of the corn variety designated CV385683. The invention thus relates to the plants, seeds and tissue cultures of the variety CV385683, and to methods for producing a corn plant produced by crossing a corn plant of variety CV385683 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV385683 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV385683. |
US08319063B2 |
Plants and seeds of corn variety CV493546
According to the invention, there is provided seed and plants of the corn variety designated CV493546. The invention thus relates to the plants, seeds and tissue cultures of the variety CV493546, and to methods for producing a corn plant produced by crossing a corn plant of variety CV493546 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV493546 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV493546. |
US08319054B2 |
Plants and seeds of hybrid corn variety CH692234
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH692234. The invention thus relates to the plants, seeds and tissue cultures of the variety CH692234, and to methods for producing a corn plant produced by crossing a corn plant of variety CH692234 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH692234. |
US08319052B2 |
Plants and seeds of hybrid corn variety CH303297
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH303297. The invention thus relates to the plants, seeds and tissue cultures of the variety CH303297, and to methods for producing a corn plant produced by crossing a corn plant of variety CH303297 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH303297. |
US08319050B2 |
Plants and seeds of hybrid corn variety CH499092
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH499092. The invention thus relates to the plants, seeds and tissue cultures of the variety CH499092, and to methods for producing a corn plant produced by crossing a corn plant of variety CH499092 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH499092. |
US08319045B1 |
Maize variety PHPJA
A novel maize variety designated PHPJA and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PHPJA with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PHPJA through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PHPJA or a trait conversion of PHPJA with another maize variety. Inbred maize varieties derived from maize variety PHPJA, methods for producing other inbred maize varieties derived from maize variety PHPJA and the inbred maize varieties and their parts derived by the use of those methods. |
US08319043B2 |
Cotton cultivar PHY 800 Pima
A cotton cultivar, designated PHY 800 Pima, is disclosed. The invention relates to the seeds of cotton cultivar PHY 800 Pima, to the plants and plant parts of cotton cultivar PHY 800 Pima and to methods for producing a cotton plant produced by crossing the cultivar PHY 800 Pima with itself or another cotton variety. The invention further relates to hybrid cotton seeds and plants produced by crossing the cultivar PHY 800 Pima with another cotton cultivar. |
US08319039B2 |
Soybean variety A1024340
The invention relates to the soybean variety designated A1024340. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1024340. Also provided by the invention are tissue cultures of the soybean variety A1024340 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1024340 with itself or another soybean variety and plants produced by such methods. |
US08319028B2 |
Soybean cultivar S080102
A soybean cultivar designated S080102 is disclosed. The invention relates to the seeds of soybean cultivar S080102, to the plants of soybean S080102, to plant parts of soybean cultivar S080102, and to methods for producing a soybean plant produced by crossing soybean cultivar S080102 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars, or breeding cultivars, and plant parts derived from soybean variety S080102, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar S080102, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing the cultivar S080102 with another soybean cultivar. |
US08319025B2 |
Soybean cultivar S070139
A soybean cultivar designated S070139 is disclosed. The invention relates to the seeds of soybean cultivar S070139, to the plants of soybean S070139, to plant parts of soybean cultivar S070139, and to methods for producing a soybean plant produced by crossing soybean cultivar S070139 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars, or breeding cultivars, and plant parts derived from soybean variety S070139, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar S070139, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing the cultivar S070139 with another soybean cultivar. |
US08319023B2 |
Soybean cultivar S080201
A soybean cultivar designated S080201 is disclosed. The invention relates to the seeds of soybean cultivar S080201, to the plants of soybean S080201, to plant parts of soybean cultivar S080201, and to methods for producing a soybean plant produced by crossing soybean cultivar S080201 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars, or breeding cultivars, and plant parts derived from soybean variety S080201, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar S080201, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing the cultivar S080201 with another soybean cultivar. |
US08319022B2 |
Soybean cultivar 8536465
A soybean cultivar designated 8536465 is disclosed. The invention relates to the seeds of soybean cultivar 8536465, to the plants of soybean 8536465, to plant parts of soybean cultivar 8536465, and to methods for producing a soybean plant produced by crossing soybean cultivar 8536465 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars, or breeding cultivars, and plant parts derived from soybean variety 8536465, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar 8536465, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing the cultivar 8536465 with another soybean cultivar. |
US08319019B2 |
Bacillus thuringiensis gene with lepidopteran activity
The invention provides nucleic acids, and variants and fragments thereof, obtained from strains of Bacillus thuringiensis encoding polypeptides having pesticidal activity against insect pests, including Lepidoptera. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests. |
US08319013B2 |
Plants and seeds of hybrid corn variety CH626058
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH626058. The invention thus relates to the plants, seeds and tissue cultures of the variety CH626058, and to methods for producing a corn plant produced by crossing a corn plant of variety CH626058 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH626058. |
US08319011B2 |
Tobacco plants having reduced nicotine demethylase activity
The present invention generally relates to methods and materials involved in producing tobacco plants having reduced levels of conversion of nicotine to nornicotine. In certain embodiments, the invention is directed to mutations in a nicotine demethylase gene, tobacco plants comprising mutations in a nicotine demethylase gene, and tobacco compositions and products thereof. In other embodiments, the invention is directed toward nicotine demethylase RNA interference, tobacco plants comprising a nicotine demethylase RNA interference transgene, and tobacco compositions and products thereof. |
US08319009B2 |
Switchgrass cultivar EG1101
A switchgrass cultivar designated EG1101 is disclosed. Also disclosed are seeds of switchgrass cultivar EG1101, plants of switchgrass EG1101, plant parts of switchgrass cultivar EG1101 and methods for producing a switchgrass plant produced by crossing switchgrass cultivar EG1101 with itself or with another switchgrass variety. Methods are also described for producing a switchgrass plant containing in its genetic material one or more transgenes and to the transgenic switchgrass plants and plant parts produced by those methods. Switchgrass cultivars or breeding cultivars and plant parts derived from switchgrass variety EG1101, methods for producing other switchgrass cultivars, lines or plant parts derived from switchgrass cultivar EG1101 and the switchgrass plants, varieties, and their parts derived from use of those methods are described herein. Hybrid switchgrass seeds, plants and plant parts produced by crossing the cultivar EG1101 with another switchgrass cultivar are also described. |
US08319006B2 |
Drapeable absorbent article
An absorbent article including a cover layer, a barrier layer and an absorbent system arranged between the cover layer and the barrier layer, the absorbent article being drapeable and possessing the absorbency attributes required of a sanitary napkin. |
US08319000B2 |
Alkylating iso-pentane with a converted olefinic feedstock
A process for reacting an iso-pentane, comprising: alkylating the iso-pentane with a converted olefinic feedstock comprising at least 5 wt % C5 olefins, wherein the C5 olefins in the converted olefinic feedstock are predominantly 2-pentene, to make a naphtha and a middle distillate, and wherein a formation of iso-butane during the alkylating is less than 35 wt % of an amount of olefins in the converted olefinic feedstock. |
US08318998B2 |
Enhanced catalyst performance for production of vinyl terminated propylene and ethylene/propylene macromers
This invention relates to a transition metal catalyst compound represented by the structure: wherein M is hafnium or zirconium; each X is, independently, selected from the group consisting of hydrocarbyl radicals having from 1 to 20 carbon atoms, hydrides, amides, alkoxides, sulfides, phosphides, halogens, dienes, amines, phosphines, ethers, or a combination thereof; each R1 and R3 are, independently, a C1 to C8 alkyl group; and each R2, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, and R14 are, independently, hydrogen, or a substituted or unsubstituted hydrocarbyl group having from 1 to 8 carbon atoms, provided however that at least three of the R10-R14 groups are not hydrogen, compositions thereof and methods of use thereof to prepare polymers. |
US08318996B2 |
Systems and methods for treating hydrogen recycle gas in a process for converting biorenewable feedstock into renewable fuels and chemicals
Systems and methods for treating hydrogen recycle gas in a process for converting biorenewable feedstock into green diesel fuel are provided. Sponge oil is provided. Hydrogen recycle gas produced during the process is contacted with the sponge oil. The sponge oil and hydrogen recycle gas are contacted in a contact drum and propane and other light hydrocarbons from the hydrogen recycle gas are absorbed into the sponge oil producing purified recycle gas and propane-rich sponge oil. The purified recycle gas is recycled into the process and the propane-rich sponge oil is fractionated to recover propane. The sponge oil may be sour sponge oil to also sulfide a deoxygenation catalyst used in the process. |
US08318992B2 |
Processes for the production of fluoropropanes and halopropenes
A process is disclosed for making CF3CF2CH3, CF3CF═CH2 and/or CF3CCl═CH2. The process involves reacting at least one starting material selected from the group consisting of halopropanes of the formula CX3CH2CH2X, halopropenes of the formula CX3CH═CH2 and halopropenes of the formula CX2═CHCH2X, wherein each X is independently F or Cl, with HF and Cl2 in a reaction zone to produce a product mixture comprising HF, HCl, CF3CF2CH3, CF3CF═CH2, and CF3CCl═CH2; and recovering the CF3CF2CH3, CF3CF═CH2 and/or CF3CCl═CH2 from the product mixture. Also disclosed is a process for making CF3CH2CHF2, CF3CH═CHF, and/or CF3CH═CHCl. This process involves reacting at least one starting material selected from the group consisting of halopropenes of the formula CX3CH═CH2 and halopropenes of the formula CX2═CHCH2X, wherein each X is independently F or Cl, with HF and Cl2 in a reaction zone to produce a product mixture comprising HF, HCl, CF3CH2CHF2, CF3CH═CHF and CF3CH═CHCl; and recovering the CF3CH2CHF2, CF3CH═CHF, and/or CF3CH═CHCl from the product mixture. The molar ratio of HF to the total amount of starting materials fed to the reaction zone for both of these processes is at least stoichiometric, and the molar ratio of Cl2 to total amount of starting material fed to the reaction zone for both of these processes is 2:1 or less. |
US08318991B2 |
Method for producing hydrogen-containing fluoroolefin compound
An unsaturated hydrogen-containing fluoroolefin compound is obtained by bringing an unsaturated fluorine-containing halogen compound into contact with 0.1 to 3 molar equivalents of hydrogen relative to the unsaturated fluorine-containing halogen compound in a vapor phase in the presence of a supported palladium catalyst in which an amount of supported palladium is 0.1% by weight to 2.5% by weight. |
US08318990B2 |
Process of producing alcohol
A subject for the invention is to provide a process of producing a dimeric alcohol in high yield with high selectivity by the Guerbet reaction conducted using an alcohol having 4 or less carbon atoms as a starting material in the presence of a complex including a transition metal and of a base. The invention relates to a process of producing an alcohol which includes dimerizing a starting-material alcohol having 4 or less carbon atoms in an environment having a partial hydrogen pressure of 0.1 MPa or higher. |
US08318988B2 |
Process for purifying a crude ethanol product
Recovery of ethanol from a crude ethanol product obtained from the hydrogenation of acetic acid. Separation and purification processes of the crude ethanol products are employed to allow recovery of ethanol and remove acetal impurities. |
US08318986B2 |
Methods for improving syngas-to-alcohol catalyst activity and selectivity
The invention herein provides methods of activating a catalyst composition. These methods include annealing a catalyst with an inert gas, under effective conditions, and then contacting the annealed catalyst with syngas to produce an activated catalyst. These steps can also be reversed. The activated catalysts can be employed to convert syngas into products, such as alcohols, with improved selectivities and yields. |
US08318983B2 |
System for controlling the reactivity of boronic acids
A protected organoboronic acid includes a boron having an sp3 hybridization, a conformationally rigid protecting group bonded to the boron, and an organic group bonded to the boron through a boron-carbon bond. A method of performing a chemical reaction includes contacting a protected organoboronic acid with a reagent, the protected organoboronic acid including a boron having an sp3 hybridization, a conformationally rigid protecting group bonded to the boron, and an organic group bonded to the boron through a boron-carbon bond. The organic group is chemically transformed, and the boron is not chemically transformed. |
US08318982B2 |
Catalyst and process for preparing an amine
A process for preparing an amine by reacting a primary or secondary alcohol, aldehyde and/or ketone with hydrogen and a nitrogen compound selected from the group of ammonia and primary and secondary amines, in the presence of a supported copper-, nickel- and cobalt-containing catalyst, wherein the catalytically active material of the catalyst, before the reduction thereof with hydrogen, comprises oxygen compounds of aluminum, of copper, of nickel, of cobalt and of tin, and in the range from 0.2 to 5.0% by weight of oxygen compounds of yttrium, of lanthanum, of cerium and/or of hafnium, each calculated as Y2O3, La2O3, Ce2O3 and Hf2O3 respectively, and catalysts as defined above. |
US08318981B2 |
Imidate compound and use thereof for pest control
There is provided a compound having an excellent controlling effect on arthropod pests represented by the formula (I-1): wherein Z represents an optionally substituted carbocyclic group or an optionally substituted heterocyclic group; G represents a -A1-R1 group, etc.; X represents a -A2-R4 group, etc.; X represents a -A2-R4 group, etc.; X0 represents a -A3-R6 group, etc.; or X and X0 are optionally taken together to form a -A2-T0-A3- group; M1 represents a —R8 group, etc.; A1, A2 and A3 independently represent an oxygen atom, etc.; R1 and R8 independently represents an optionally substituted C1-C20 chain hydrocarbon group, etc.; R4 and R6 independently represent an optionally substituted C1-C6 chain hydrocarbon group, etc.; and T0 represents an optionally substituted C2-C6 alkanediyl group. |
US08318974B2 |
Drying agent and method for forming the same
One embodiment of the present invention discloses a drying agent having the formula: [Mg2(BTEC)(H2O)m].nH2O, where m denotes zero or positive integer from 1 to 10, and n denotes zero or positive integer from 1 to 6. Another embodiment of the present invention provides a method for forming a drying agent. |
US08318973B2 |
Functionalized sinapic acid and methyl sinapate
The present invention relates to compounds of formula I, which are functionalized phenolic compounds, and polymers formed from the same. Ar—[O—(X)p—R′]q I Polymers formed from the functionalized phenolics are expected to have controllable degradation profiles, enabling them to release an active component over a desired time range. The polymers are also expected to be useful in a variety of medical applications. |
US08318970B2 |
Process for preparing (meth)acrylates of C10-alcohol mixtures
Process for preparing (meth)acrylates of C10-alcohol mixtures, by reacting (meth)acrylic acid with an isomer mixture of C10-alcohols composed of 2-propylheptanol as the main isomer and at least one of the C10-alcohols 2-propyl-4-methylhexanol, 2-propyl-5-methylhexanol, 2-isopropylheptanol, 2-isopropyl-4-methylhexanol, 2-isopropyl-5-methylhexanol and/or 2-propyl-4,4-dimethylpentanol, in the presence of at least one acidic catalyst and of at least one polymerization inhibitor and in the presence of a solvent which forms an azeotrope with water, the azeotrope is distilled off and condensed, and the condensate splits into an aqueous phase and an organic phase, wherein a) the esterification is performed in a reactor with a circulation evaporator and b) in the presence of a solvent, and c) the crude product is purified by subsequent purifying distillation. |
US08318962B2 |
Process for recovering sterols from a crude source containing sterol esters
A process of obtaining sterols suitable for human consumption from a crude wood pulping source containing sterol esters is disclosed. The sterols are obtained at high yield and purity. In particular, a process of obtaining sterols at high yield and purity from tall oil pitch (TOP) is disclosed. The sterols obtained can be esterified to sterol esters for use in dietary supplements and as additives for food and beverage products. |
US08318961B2 |
Oligomers of cholesterol, cholesterol sulphate and cholesterol esters and also drugs containing these
The invention relates to new substances which are derived from cholesterol, cholesterol sulphate and cholesterol esters of a natural, semi-synthetic or synthetic origin in that they represent oligomers with a specific type of cross-linkage of the starting substances based on cholesterol. |
US08318957B2 |
Semisynthesis process for the preparation of 10 deacetyl-N-debenzoyl-paclitaxel
A process for the preparation of 10-deacetyl-bis-7,10-trichloroacetylbaccatin III (VI) said process comprising: reacting 10-deacetylbaccatin III with a trichloroacetic acid activated derivative to obtain a reaction mixture, and performing an isolation step on said reaction mixture obtain purified 10-deacetyl-bis-7,10-trichloroacetylbaccatin III (VI) having a content, of corresponding 7- or 10 mono-trichloroacetyl derivatives lower than 0.1% as determined by HPLC. |
US08318955B2 |
Process for preparing 2,4-dioxotetrahydrofuran-3-carboxylates
Process for preparing 2,4-dioxotetrahydrofuran-3-carboxylates of the formula (I) and/or (I′) comprising the reaction of a haloacetyl chloride compound of the formula (II) with a malonic ester of the formula (III) in which Hal, R1 and R2 have the definitions stated in the application, in the presence of a suitable base and optionally in the presence of a solvent; the addition of a sufficient amount of water to the reaction mixture; and the isolation of the desired 2,4-dioxotetrahydrofuran-3-carboxylate. |
US08318951B2 |
Stem cell differentiating agents and uses therefor
The present invention relates to screens for compounds that can induce stem cell differentiation. In addition, isoxazoles and sulfonyl hydrazones are identified as general classes of compounds that can induce differentiation of stem cells into cells of neuronal and cardiac fate, respectively. |
US08318949B2 |
Organic compounds
The present invention provides heterocyclic derivatives that modulate the activity of stearoyl-CoA desaturase. Methods of using such derivatives to modulate the activity of stearoyl-CoA desaturase and pharmaceutical compositions comprising such derivatives are also encompassed. |
US08318948B2 |
Fluorene derivatives and organic electronic device using the same
Disclosed is a novel fluorene derivative and an organic electronic device using the same. The organic electronic device has excellent efficiency, driving voltage, and a lifespan. |
US08318944B2 |
Hydroxy-6-heteroarylphenanthridines and their use as PDE4 inhibitors
Compounds of the formula Ia***** in which the substituents have the definitions provided in the specification, are novel, effective PDE4 inhibitors. |
US08318941B2 |
Pyridone/hydroxypyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
Novel compounds are provided which are 11-beta-hydroxysteroid dehydrogenase type I inhibitors. 11-beta-hydroxysteroid dehydrogenase type I inhibitors are useful in treating, preventing, or slowing the progression of diseases requiring 11-beta-hydroxysteroid dehydrogenase type I inhibitor therapy. These novel compounds have the structure formula (I) enantiomers, diastereomers, solvates, salts, tautomers or prodrugs thereof wherein, A, W, X, Y and R1 are defined herein. |
US08318935B2 |
Organic compounds 75074
A compound of formula (I), or tautomers, or stereoisomers, or solvates, or pharmaceutically acceptable salts thereof, wherein M1, M2, L1, L2, W1, W2, X1, X2, Y1, Y2, A, R5 and R5a are as defined herein for the for treatment of conditions treatable by the blockade of an epithelial sodium channel, particularly conditions benefiting from mucosal hydration. |
US08318930B2 |
Process for preparing polymorphic forms of (S)-6-chloro-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one
Disclosed herein is a novel process for preparing polymorphic Forms of (S)-6-chloro-(cyclopropylethynyl)-1,4-di-hydro-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one referred as M1, I, II, β, and ω. |
US08318929B2 |
4-aryl-2-anilino-pyrimidines
The present invention relates to compounds of Formula (Ia) or (Ib), the N-oxide forms, pharmaceutically acceptable addition salts, quaternary amines, stereoisomers, tautomers, racemics, metabolites, prodrugs, hydrates, or solvates thereof, wherein Y1, m, n, R1; X1; X2; R2; X3; X4; R3; and R4 have the meaning defined in the claims. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use in therapy. The invention particularly relates to compounds that are kinase inhibitors useful for the treatment of disease states mediated by kinase, especially PLK4, in particular such compounds that are useful in the treatment of pathological processes which involve an aberrant cellular proliferation, such as tumor growth, rheumatoid arthritis, restenosis and atherosclerosis. |
US08318925B2 |
RNAi therapeutic for treatment of hepatitis C infection
Small interfering RNAs (siRNAs) or small hairpin RNA (shRNAs) and compositions comprising same are provided that specifically target human cyclophilin A (CyPA) to effectively inhibit Hepatitis C (HCV) infection in a cell. Such siRNA and shRNAs may have a length of from about 19 to about 29 contiguous nucleotides corresponding to a specific region of human cyclophilin A (CyPA) cDNA of from about nucleotide 155 to about nucleotide 183 having particular potency against CyPA and HCV. Such siRNA and shRNAs may be formulated as naked compositions or as pharmaceutical compositions. DNA polynucleotides, plasmids, and viral or non-viral vectors are also provided that encode siRNA or shRNA molecules, which may be delivered directly to cells or in combination with known delivery agents, such as lipids, polymers, encapsulated lipid particles, such as liposomes. Methods for treating, managing inhibiting, preventing, etc., HCV infection using such siRNA and shRNAs and compositions comprising same are also provided. |
US08318919B2 |
Nucleic acid hybridization methods
Disclosed herein are methods of destabilizing double-stranded nucleic acid hybridization using an enzyme comprising DNA N-glycosylase activity. Also disclosed herein is the detection of a double-stranded target DNA wherein the hybridization of duplex strands has been at least partially disrupted thereby permitting invasion of a probe strand. Also disclosed herein are methods of using an enzyme comprising DNA N-glycosylase activity to generate single-stranded circular nucleic acids. |
US08318918B2 |
Chalcone 3-hydroxylase
The present invention relates to an isolated nucleic acid molecule, comprising a nucleotide sequence, which encodes a polypeptide with chalcone 3-hydroxylase activity, wherein the nucleotide sequence comprises SEQ ID NO. 1 or has at least a 60% identity with SEQ ID NO. 1 or is able to hybridize with a molecule comprising the sequence of SEQ ID NO. 1, wherein the nucleotide sequence encodes a polypeptide, which comprises the motif FASRPLSX1X2G(X3)m(GSAGGD)n (SEQ ID NO. 3), wherein X1 is threonine or serine, X2 is alanine or glycine, X3 is any amino acid, m is an integer between 50 and 200, and n is 0 or 1. |
US08318912B2 |
Targeted immune conjugate comprising an antibody to glycophorin A and a M2e peptide
Disclosed herein are materials and methods related to vaccines. Materials and methods for delivery of immunogens to the reticuloendothelial system via non-circulating lymphoid cells are provided. |
US08318910B2 |
IL-13 receptor antibodies
This invention relates to monoclonal and polyclonal antibodies capable of specifically recognizing IL-13 receptor α and uses thereof. |
US08318899B2 |
Lytic domain fusion constructs and methods of making and using same
The invention relates to fusion constructs, methods of using fusion constructs and methods of treating undesirable or aberrant cell proliferation or hyperproliferative disorders, such as tumors, cancers, neoplasia and malignancies. |
US08318897B2 |
Nucleotide and amino acid sequences encoding an exported protein 1 derived from Plasmodium vivax and uses thereof
The present invention is directed to novel polynucleotides and polypeptides directed to EXP1 of Plasmodium vivax, and methods of using these polynucleotides and polypeptides in the detection of P. vivax antibodies or anti-P. vivax antibodies in a subject. The invention finds particular useful application in identifying recent exposure to P. vivax. |
US08318896B2 |
Chromatography of polyolefin polymers
A method for multi-dimensional chromatography of a polyolefin polymer, comprising introducing a solution of the polyolefin polymer into a liquid flowing through a first liquid chromatography stationary phase or a field flow fractionation device and subsequently flowing the solution through a second liquid chromatography stationary phase, the second liquid chromatography stationary phase comprising graphitic carbon, the polyolefin polymer emerging from the liquid chromatography stationary phase with a retention factor greater than zero. |
US08318895B1 |
Recycling superabsorbent polymer fines
A process is described for recycling superabsorbent polymer fines into a process that includes treating the superabsorbent polymer fines with caustic and a polymerization step for making the superabsorbent polymer gel. The process requires treating the superabsorbent polymer fines with a caustic, followed by mixture with polymerizable monomer solution, and polymerizing the mixture of the superabsorbent polymer fines and monomer to form the aqueous fluid absorbent polymer. In the process, the fines are incorporated into the new polymer gel and become indistinguishable there from. The gel may then be comminuted into a particulate dried and then separated into a portion having a desired minimum particle size in a fines portion having less than the desired size. The particulate may then be coated with a surface crosslinking agent and surface additives and heated for surface conversion. |
US08318891B2 |
Copolycarbonate-polyesters, methods of manufacture, and uses thereof
A copolycarbonate-polyester, comprising units of formula wherein at least 60 percent of the total number of R1 groups are divalent aromatic organic radicals and the balance thereof are divalent aliphatic or alicyclic radicals; units of formula wherein T is a C7-20 divalent alkyl aromatic radical or a C6-20 divalent aromatic radical, and D is a divalent C6-20 aromatic radical; and units of the formula wherein R2 and R3 are each independently a halogen or a C1-6 alkyl group, R4 is a methyl or phenyl group, each c is independently 0 to 4, and T is as described above. A method of making a copolycarbonate-polyester is also disclosed. |
US08318890B2 |
Polycarbonate diol
A polycarbonate diol which is useful as a raw material compound for producing a polycarbonate-based polyurethane having a sufficient mechanical strength and excellent in a balance of physical properties such as oil resistance, hydrolysis resistance, and weather resistance and which is amorphous. The polycarbonate diol includes repeating units of the below-shown formula (A) and the below-shown formula (B), wherein both terminal groups are hydroxyl groups, the ratio of the below-shown formula (A) to the below-shown formula (B) is 99:1 to 1:99 by mol, and number-average molecular weight is 300 to 10,000. |
US08318889B2 |
Organic polyurethane shape memory material and a preparation method thereof
An organic polyurethane shape memory material includes a C10 chain or C18 chain and consists of hard segment and soft segment. The material is produced by reacting the single-chain type dendrimer with diethylenetriamine to produce dendrimer. Then dendrimer reacts with N-(3-aminopropyl)diethanolamine to produce dendritic diols. Next, polymer HO(C6H10O2)xC2H4OC2H4(C6H10O2)yOH, where x+y=25˜26, reacts with methylenedi-p-phenyl diisocyanate, and at least one type of dendritic diols is added to produce the organic polyurethane shape memory material. |
US08318887B2 |
Siloxane composite-based light-weight optical lenses
Disclosed is a process of preparing a moulded article, comprising 1) hydrolyzing a) at least one silane having one non-hydrolysable organic group, and b) at least one compound selected from b1) a silane having two non-hydrolysable organic groups, and b2) a hydrolysable polysiloxane, or a mixture thereof, and c) optionally at least one silane having no non-hydrolysable organic group, to prepare a composite composition comprising a hydrolysate or condensate, 2) placing the composite composition in a mould, 3) curing the composite composition to increase the degree of condensation, 4) removing the moulded article from the mould, and 5) heat treating the moulded article at a temperature of at least 100° C. The moulded article is preferably an optical lens which may be used for automobile headlights. |
US08318885B2 |
Curable resin composition, cured product thereof, and various articles derived from those
A curable resin composition which is easily cured by heating or ultraviolet irradiation and capable of forming a thick cured film due to low shrinkage. This curable resin composition enables to obtain a cured product satisfying various characteristics such as heat resistance, chemical resistance, high surface hardness and high refractive index. Also disclosed is a cured product obtained from such a composition. Specifically disclosed is a curable resin composition containing at least one substance selected from the group consisting of condensates (A) obtained by hydrolyzing and condensing a thiol group-containing alkoxysilane (a1) represented by the following general formula: R1Si(OR2)3 (1) (wherein, R1 represents a hydrocarbon group having at least one thiol group and 1-8 carbon atoms or an aromatic hydrocarbon group having at least one thiol group, and R2 represents a hydrogen atom, a hydrocarbon group having 1-8 carbon atoms or an aromatic hydrocarbon group), compounds (B) having an epoxy group, compounds (C) having an isocyanate group and compounds (D) having a carbon-carbon double bond. |
US08318882B2 |
Anionic water-soluble additives based on allyl ether and vinyl ether
The invention relates to anionically modified copolymers that can be obtained by the polymerization of the monomers (A), (B) and (C), obtaining non-ionic polymers containing reactive terminal OH groups, and by subsequent conversion of the terminal OH groups to form anionic end groups, (A) being a monomer of formula (I) wherein A is C2-C4 alkylene and B is a C2-C4alkylene different from A, k corresponds to the number 0 or 1, m is a number between 0 and 500, preferably between 0 and 50, n is a number between 0 and 500, preferably between 0 and 50, the sum of m+n being equal to between 1 and 1000; (B) contains an ethylenically unsaturated monomer containing an aromatic group; and (C) is an ethylenically unsaturated monomer containing an alkyl radical. |
US08318876B1 |
Thermoset polymers via ring opening metathesis polymerization of functionalized oils
The invention provides a method for producing a thermosetting resin from renewable oils, the method comprising supplying renewable oil molecules containing strained ring alkene moieties; reacting the alkene moieties with cyclic alkenes to create a polymer; and repeating the above two steps until the resin having desired characteristics are obtained. Also provided is a thermoset resin comprising functionalized renewable oil polymerized with a co-monomer. |
US08318872B2 |
Method for controlling bimodal catalyst activity during polymerization
A method of performing a polymerization reaction in a gas phase polymerization reactor to produce a bimodal polymer while controlling activity of a bimodal polymerization catalyst composition in the reactor by controlling concentration of at least one induced condensing agent (‘ICA’) in the reactor is provided. In some embodiments, the ICA is isopentane (or another hydrocarbon compound) and the bimodal catalyst composition includes a Group 15 and metal containing catalyst compound (or other HMW catalyst for catalyzing polymerization of a high molecular weight fraction of the product), and a metallocene catalyst compound (or other LMW catalyst for catalyzing polymerization of a low molecular weight fraction of the product). |
US08318871B2 |
Process for preparing a polymer
The present invention relates to a process which comprises preparing polymers. The process uses an appropriate installation, and may comprise determining at least one parameter of a physical and/or chemical conversion. The invention also relates to a corresponding screening process. According to this process, a polymerization reaction medium is made to flow in a tubular flow member. |
US08318868B2 |
Isocyanate-containing thermoplastic polyurethane
Thermoplastic polyurethane (i) comprising from 20% by weight to 70% by weight of isocyanate dissolved in the thermoplastic polyurethane, based on the total weight of the thermoplastic polyurethane (i) comprising the isocyanates. |
US08318861B2 |
Rubber composition and tire using the same
This invention relates to a rubber composition capable of using in a tread rubber of a tire to improve both an initial gripping performance and a running stability of the tire as compared with those of conventional tires, and more particularly to a rubber composition formed by compounding an indene-containing C9-based resin having a softening point of 130° C.-190° C. and an indene content of 30-80 mass % into a rubber component. |
US08318860B1 |
Method for fluid-phase synthesis of a polymer
The invention relates to a method for the fluid-phase synthesis of a polymer formed from n monomers. |
US08318858B2 |
Conjugated diene polymer, conjugated diene polymer composition, and method for producing conjugated diene polymer
A conjugated diene polymer is provided that comprises a conjugated diene-based constituent unit and a constituent unit of formula (I) below, at least one terminus of the polymer being modified by a compound of formula (II): wherein X1, X2, and X3 independently denote a group of formula (Ia) below, a hydroxy group, a hydrocarbyl group, or a substituted hydrocarbyl group, and at least one of X1, X2, and X3 is a group of formula (Ia) below or a hydroxy group, wherein R1 and R2 independently denote a hydrocarbyl group having 1 to 6 carbon atoms, a substituted hydrocarbyl group having 1 to 6 carbon atoms, a silyl group, or a substituted silyl group, and R1 and R2 may be bonded so as to form, together with the nitrogen atom, a ring structure, wherein n denotes an integer of 1 to 10, R3, R4, and R5 independently denote a hydrocarbyl group having 1 to 4 carbon atoms or a hydrocarbyloxy group having 1 to 4 carbon atoms, at least one of R3, R4, and R5 is a hydrocarbyloxy group, and A denotes a nitrogen atom-containing functional group. |
US08318851B2 |
Weatherable resinous compositions
Disclosed are compositions comprising: (i) 5-45 wt. % of an acrylonitrile-styrene-acrylate (ASA) graft copolymer or acrylate-modified ASA, (ii) 2-82 wt. % of at least one polyestercarbonate which is a block polyestercarbonate comprising organic carbonate blocks alternating with arylate blocks, said arylate blocks comprising ester structural units derived from at least one 1,3-dihydroxybenzene moiety and at least one aromatic dicarboxylic acid, and having a degree of polymerization of at least about 4; and (iii) 5-60 wt. % of at least one rigid thermoplastic polymer comprising structural units derived from styrene and acrylonitrile; alpha-methylstyrene and acrylonitrile; alpha-methylstyrene, styrene, and acrylonitrile; styrene, acrylonitrile, and methyl methacrylate; alpha-methyl styrene, acrylonitrile, and methyl methacrylate; or alpha-methylstyrene, styrene, acrylonitrile, and methyl methacrylate, or mixtures thereof, wherein wt. % values are based on the weight of components (i)-(iii) and wherein a molded article made from the composition has a notched Izod impact strength of at least 5 kilojoules per square meter (kJ/m2) as determined according to ISO 180 at room temperature and a Vicat B value of at least 101° C. determined at 120° C. according to ISO 306. Articles made from said compositions are also disclosed. |
US08318847B2 |
Plastic compositions and products produced therefrom
In one embodiment, a plastic composition can comprise: a plastic, a white pigment, and a non-white colorant. The composition can have a whiteness index of greater than or equal to about 50, and a composition yellowness index of less than 10, as measured on a 3 mm thick color chip under D65 illuminant and 2 degree observer. Also disclosed are articles made from the plastic composition. |
US08318844B2 |
Oil-dispersible composite of metallic nanoparticle and method for synthesizing same
The present invention provides an oil-dispersible composite of metallic nanoparticles and a method for synthesizing the same. The composite primarily includes metallic nanoparticles and an oily polymeric polymer such as polyurethane (PU). The oily polymeric polymer serves as a carrier of the metallic nanoparticles by chelating therewith so that the metallic nanoparticles are dispersed uniformly. In the method of the present invention, the metallic ions are first chelated by the oily polymeric polymer and then reduced into nanoparticles. The composite of the present invention is about 5 to 100 nm in particle size. |
US08318841B2 |
Binder for air-drying paint comprising nanoparticle bonded silicon derivative of unsaturated fatty acid
A binder for air drying paint, based on metal oxide-containing nanoparticles with unsaturated organic branches. At least one metal atom of the nanoparticle is chemically bound to an organic branch with at least one unsaturated ethylenic functionality. A process for preparation of the binder. |
US08318839B2 |
Puncture sealant
The present invention provides a tire puncture sealant which has a reduced viscosity at low temperatures and better injectability at low temperatures while exerting excellent initial sealing performance and storage stability. The present invention also provides a tire puncture sealant which further has better injectability at high temperatures while exerting the seal retention performance. The present invention relates to a tire puncture sealant including: a natural rubber latex; a tackifier; and propylene glycol, wherein the amount of the propylene glycol in 100% by mass of a liquid portion of the puncture sealant is 55% by mass or more, and also relates to a tire puncture sealant including: a natural rubber latex; a tackifier; propylene glycol; and a nonionic surfactant, wherein the nonionic surfactant is a polyoxyalkylene alkyl ether and/or a polyoxyalkylene alkenyl ether. |
US08318837B2 |
Method for controlling water resistance of polyglycolic acid resin
A method of controlling a moisture resistance of polyglycolic acid resin, by controlling a total carboxyl group-source concentration including a contribution of residual glycolide. As a result, a moisture resistance governing the change of strength with time of the polyglycolic acid resin is controlled at a good accuracy. |
US08318834B2 |
Epoxy resin reactive diluent compositions
An epoxy resin reactive diluent composition comprises an epoxy resin diluent (A) and a resin compound (B), wherein the epoxy resin diluent (A) comprises a cis, trans-1,3- and -1,4-cyclohexanedimethylether moiety; and wherein the resin compound (B) comprises one or more epoxy resins other than the epoxy resin diluent (A). A curable epoxy resin composition comprises the epoxy resin reactive diluent composition and a curing agent and/or curing catalyst therefore. A cured epoxy resin is prepared by curing the curable epoxy resin composition. |
US08318829B2 |
Methylene bis(cyclohexylamine)-initiated polyols and rigid polyurethane foam made therefrom
Polyether polyols are initiated with methylene bis(cyclohexylamines). The polyols are useful in making rigid polyurethane foams, especially foams for pour-in-place applications, where they give a good combination of low k-factor and short demold times. |
US08318827B2 |
Insect resistant polyurethane foam
The invention described herein relates to an essentially closed-cell two-component polyurethane foam containing an pesticide, which upon curing provides a barrier to insect infestation. |
US08318824B2 |
Hydrophilic polyolefin sintered body
Disclosed is a hydrophilic polyolefin sintered material which is a water-absorbing sintered material of a polyolefin resin ice having a graft chain composed of at least one molecular chain selected from hydrophilic ethylenically unsaturated group-containing monomers and their polymers. This hydrophilic polyolefin sintered material has an average porosity of 20-80% by volume and an open cell having an average pore diameter of 1-150 μm. |
US08318822B2 |
Vibration damping and sound absorbing material and production process thereof
It is an object of the invention to provide a vibration damping and sound absorbing material containing a plant-derived polyol which material largely contributes a decrease of environmental load and has excellent vibration damping and sound absorbing properties, and it is another object of the invention to provide a production process of the material. Specifically, disclosed is a vibration damping and sound absorbing material which is suitably used for cars. A vibration damping and sound absorbing material comprises a polyurethane foam which comprises, as raw materials, a polyol and/or a polymer-dispersed polyol in which polymer fine particles obtainable by polymerizing an unsaturated bond-containing compound are dispersed in a polyol, and water, a catalyst and a polyisocyanate, wherein the polyol comprises (A) a plant-derived polyol produced using a raw material obtainable by a plant. |
US08318821B2 |
Rigid foamed synthetic resin and process for its production
Provided is a process for producing a rigid foamed synthetic resin, wherein, as a blowing agent, a hydrocarbon compound and water are used, and a rigid foamed synthetic resin provided with dimensional stability, heat insulating properties, and possibly reduced weight can be obtained. The process involves reacting a polyol (P) with a polyisocyanate (I) in the presence of a blowing agent, a foam stabilizer and a catalyst, wherein the blowing agent has at least a C2-8 hydrocarbon compound and water; the polyol (P) has a specific polyesterpolyol (A), a specific polyetherpolyol (B), and a polymer-dispersed polyol (Z) having fine polymer particles (M) dispersed; and the isocyanate index of the polyol (P) and the polyisocyanate (I) is over 200 and at most 400. |
US08318820B2 |
Degradable polyurethane foams
A method of synthesizing of a biocompatible and biodegradable polyurethane foam includes the steps of: mixing at least one biocompatible polyol, water, at least one stabilizer, and at least one cell opener, to form a resin mix; contacting the resin mix with at least one polyisocyanate to form a reactive liquid mixture; and reacting the reactive liquid mixture form a polyurethane foam. The polyurethane foam is preferably biodegradable within a living organism to biocompatible degradation products. At least one biologically active molecule having at least one active hydrogen can be added to form the resin mix. |
US08318818B2 |
Topical composition, topical composition precursor, and methods for manufacturing and using
A tropical composition is provided. The topical composition can be prepared by diluting a topical composition precursor with water and adding additional components, if desired. The topical composition precursor can be prepared by melt processing a hydrophobic polymer composition that includes repeating pyrrolidone/alkylene groups wherein the alkylene groups contain at least 10 carbon atoms, and a hydrophilic polymer composition including repeating carboxylic groups and/or repeating hydroxyl groups. A topical composition precursor and methods for manufacturing and using a topical composition are provided by the invention. |
US08318815B2 |
Method for treatment of tumors using nordihydroguaiaretic acid derivatives
Use of nordihydroguaiaretic derivatives to suppress CDC-2 and survivin, stimulate apoptosis, and treat tumors. |
US08318814B2 |
Glyceryl ether compounds and their use
Glyceryl ether compounds prepared by the reaction of glycerol and olefin epoxides are disclosed. The compounds are renewable biomass-based surfactants useful as detergents and emulsifiers in formulations for cleaning, laundry, personal care, cosmetics, and industrial uses. |
US08318812B2 |
Therapeutic agents for the treatment of lymphoid malignancies
Methods—for treatment and prevention of lymphoid malignancies, including, but not limited to acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), B-cell lymphoma, Acute Myeloid leukemia (AML), and mantle cell lymphoma (MCL). The methods include administration of a therapeutically effective amount of FTY720 (2-Amino-2-[2-(4-octylphenyl)ethyl]propane 1,3-diol hydrochloride) or a derivative, pharmaceutically acceptable salt thereof, or a prodrug thereof to a subject. |
US08318811B2 |
Method for treating an inflammatory bowel disease using 2-amino-2-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]ethyl-1,3-propanediol or a salt thereof
A novel therapeutic and prophylactic agent for inflammatory bowel diseases and a method for treating inflammatory bowel diseases is provided. The agent comprises a 2-amino-1,3-propanediol derivative (e.g., 2-amino-2-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]ethyl-1,3-propanediol hydrochloride) represented by the chemical formula (1) or a pharmaceutically acceptable salt or hydrate thereof: The agent is useful in the treatment or prevention of Crohn's disease, Crohn's disease in large intestine, intestinal Behcet's disease, ulcerative colitis, bleeding rectal ulcer and pouchitis. |
US08318808B2 |
Zn2+chelating motif-tethered short-chain fatty acids as a novel class of histone deacetylase inhibitors
Zn2+-chelating motif-tethered fatty acids as histone deacetylase (HDAC) inhibitors. Compounds performed well in in vitro and in vivo tests. |
US08318807B2 |
Pterostilbene cocrystals
Cocrystals of pterostilbene are disclosed, including: pterostilbene:caffeine cocrystal, pterostilbene:carbamazepine cocrystal, pterostilbene:glutaric acid cocrystal, and pterostilbene:piperazine cocrystal. The pterostilbene:caffeine cocrystal is polymorphic. Forms I and II of the pterostilbene:caffeine cocrystal are disclosed. The therapeutic uses of the pterostilbene cocrystals and of pharmaceutical/nutraceutical compositions containing them are also disclosed. The disclosure sets out various methods of making and characterizing the pterostilbene cocrystals. |
US08318805B2 |
Modulation of nitric oxide synthases by betaines
The present invention relates to therapeutic compositions of betaines and L-arginine and physiologically acceptable salts thereof, and to pharmaceutical uses of betaines for up-regulating, enhancing, stimulating, controlling and/or increasing constitutive nitric oxide synthase expression a mammal, particularly in a human. Additionally, the betaines are believed to augment after administration both immunological and functional (activity) expression of Tissue Factor Pathway Inhibitor (TFPI) in a mammal, particularly a human. |
US08318804B2 |
Antiviral activity of cyclopentene nitro-ester and derivatives
Disclosed is a method of synthesizing new optically pure heterocyclic compounds using Pd(0) catalyzed intramolecular cyclizations. Analogs of cyclopentanes, like isoxazoline-2-oxide and furan, with similar framework to the cyclopentanes act as anti-HIV and anticancer agents which opens a whole new field for application of these compounds. Starting from a meso-diol, optically pure compounds were prepared without utilizing chiral ligands at any stage of the synthesis. The stereochemical outcome of the product (>99% ee) was influenced by desymmetrization catalyzed by Pseudomonas cepacia lipase and the stereo selective nature of the palladium catalyzed transformations. |
US08318803B2 |
EC SOD and use thereof
The present invention relates to an EC SOD and the use thereof. More particularly, the present invention relates to an EC SOD and the use thereof for preventing or treating skin diseases, particularly dermatitis or psoriasis. |
US08318799B2 |
Therapeutic agent for substance dependence
The present invention provides a therapeutic agent for substance dependence, which prevents relapse/recurrence of compulsive substance-taking behavior based on craving for addictive substances such as stimulant substances, opioids, barbiturate type anesthetics, hallucinogens, cocaine, hemp, cannabis, alcohol, or volatile organic solvents. (−)-1-(Benzofuran-2-yl)-2-propylaminopentane or a pharmacologically acceptable acid addition salt thereof is useful as a therapeutic agent for substance dependence, which prevents relapse/recurrence of compulsive substance-taking behavior associated with craving for addictive substances. |
US08318798B2 |
Therapeutic agent for neurodegenerative disease
[Problems] To provide a neuronal cell death inhibitor and a therapeutic agent for a neurodegenerative disease, particularly Parkinson's disease.[Means for Solving Problems] It is known that DJ-1 protein is involved in Parkinson's disease and is capable of inhibiting neuronal cell death caused by oxidative stress. Based on this knowledge, screening is made for a low molecular weight molecule capable of binding to an active site of DJ-1 protein (i.e., a region around a cysteine residue at position-106) using an analysis softwear FastDock (Fujitsu Ltd.). When various tests are made using candidate low molecular weight compounds each having a binding energy of −60 kcal/mol or lower, these compounds show a therapeutic effect on a neurodegenerative disease. |
US08318794B2 |
Method of use of porphyrins in preparing a medicament for sonodynamic therapy and a method of sonodynamic therapy using porphyrins
The invention provides method of use of a porphyrin compound as shown below in preparing a medicament for sonodynamic therapy, and a method of sonodynamic therapy using a porphyrin compound. Said therapy comprises administering a porphyrin compound to a patient and applying sonic wave to the patient, wherein each symbol has the meaning as defined in the description. |
US08318793B2 |
Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors
The present invention relates to novel heterocyclic compounds which are useful for inhibiting glycogen synthase kinase 3 (GSK-3), methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds. |
US08318788B2 |
Layered pharmaceutical formulations
In one embodiment a layered pharmaceutical formulation includes two or more pharmaceutical layers and an intermediate layer disposed between at least two of the two or more pharmaceutical layers, the intermediate layer configured to dissolve in vivo to thereby leave the two or more pharmaceutical layers substantially intact. In one embodiment, an active pharmaceutical ingredient in at least one of the pharmaceutical layers is selected from bupropion, zonisamide, naltrexone, topiramate, phentermine, metformin, olanzapine and fluoxetine. |
US08318785B2 |
Pharmaceutical compounds
Compounds of formula (I) exhibit COMT enzyme inhibiting activity and are thus useful as COMT inhibitors. |
US08318782B2 |
Mitotic kinesin inhibitor
A mitotic kinesin Eg5 inhibitor which comprises a thiadiazoline derivative represented by the general formula (I) or a pharmacologically acceptable salt thereof as an active ingredient: [wherein R1 represents a hydrogen atom and the like, R2 represents a hydrogen atom, —C(═W)R6 (wherein W represents an oxygen atom or a sulfur atom, and R6 represents substituted or unsubstituted lower alkyl and the like) and the like, R3 represents —C(═Z)R19 (wherein Z represents an oxygen atom or a sulfur atom, and R19 represents substituted or unsubstituted lower alkyl and the like) and the like, R4 represents substituted or unsubstituted lower alkyl and the like, and R5 represents substituted or unsubstituted aryl and the like] and the like are provided. |
US08318781B2 |
G-protein-conjugated receptor agonist
Disclosed is a novel aralkyl carboxylic acid compound which has an agonistic activity on GPR-120 and/or GPR-40, particularly GPR-120, and is therefore useful as an appetite regulator, an anti-obesity agent, a therapeutic agent for diabetes, a pancreatic beta differentiating cell growth enhancer, a therapeutic agent for metabolic syndrome, a therapeutic agent for a gastrointestinal disease, a therapeutic agent for a neuropathy, a therapeutic agent for a mental disorder, a therapeutic agent for a pulmonary disease, a therapeutic agent for a pituitary hormone secretion disorder or a lipid flavoring/seasoning agent. The aralkyl carboxylic acid compound is represented by the general formula (I). (I) wherein the ring Q represents a pyridyl or the like; R1 represents a C1-6 alkyl group or the like; R2 represents a hydrogen atom, a C1-4 alkyl group or a C1-4 alkoxy group; m and n independently represent an integer of 1 to 5; and X represents an oxygen atom, a sulfur atom or —NR3— [wherein R3 represents a hydrogen atom or a C1-4 alkyl group]. |
US08318779B2 |
Lysine related derivatives as HIV aspartyl protease inhibitors
The present invention concerns lysine related derivatives, their use as protease inhibitors, in particular as HIV aspartyl protease inhibitors, processes for their preparation as well as pharmaceutical compositions and diagnostic kits comprising them. The present invention also concerns combinations of the present lysine related derivatives with another anti retroviral agent. It further relates to their use in assays as reference compounds or as reagents. |
US08318772B2 |
Amine compounds and medical uses thereof
The present invention relates to a new amine compound or a pharmaceutically acceptable salt thereof, wherein the definitions of X, R1, R2 and n are given in the description, to a pharmaceutical composition containing the compound as active ingredient, and to use of the amine compound or its pharmaceutically acceptable salt for the manufacture of an anti-depressent drug. |
US08318769B2 |
Substituted sulfonamide compounds
Substituted sulfonamide compounds corresponding to formula I: processes for the preparation thereof, pharmaceutical compositions containing these compounds, and the use of such substituted sulfonamide compounds in pharmaceutical compositions for the treatment and/or inhibition of pain and other conditions at least partly mediated by the bradykinin 1 receptor. |
US08318767B2 |
Substituted imidazoles as bombesin receptor subtype-3 modulators
Certain novel substituted imidazoles are ligands of the human bombesin receptor and, in particular, are selective ligands of the human bombesin receptor subtype-3 (BRS-3). They are therefore useful for the treatment, control, or prevention of diseases and disorders responsive to the modulation of BRS-3, such as obesity, and diabetes. |
US08318762B2 |
Pyrazolospiroketone acetyl-CoA carboxylase inhibitors
The invention provides compounds of Formula (1) or a pharmaceutically acceptable salt of said compound, wherein R1, R2, and R3 are as described herein; pharmaceutical compositions thereof; and the use thereof in treating diseases, conditions or disorders modulated by the inhibition of acetyl-CoA carboxylase enzyme(s) in an animal. |
US08318759B2 |
Pyrrolidine derivatives as NK3 receptor antagonists
The present invention relates to a compounds of formula I wherein A, Ar, R, R2, R3, R4, p, and o are as defined in the specification and claims or to a pharmaceutically active salt thereof. The present compounds are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, bipolar disorders, anxiety and attention deficit hyperactivity disorder (ADHD). |
US08318751B2 |
Pyrimidinone derivatives and methods of use thereof
The present invention relates to Pyrimidinone Derivatives, compositions comprising a Pyrimidinone Derivative, and methods of using the Pyrimidinone Derivatives for treating or preventing obesity, diabetes, a metabolic disease, a cardiovascular disease or a disorder related to the activity of GPR119 in a patient. |
US08318746B2 |
Nitrogen-containing five-membered heterocyclic compound
The present invention provides a compound represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof. The compound of the present invention has a glucokinase activity, and is useful as a medicament such as an agent for the prophylaxis or treatment of diabetes, obesity and the like, and the like. |
US08318741B2 |
Therapeutic compositions and methods
The present invention relates in general to therapeutic compositions and methods of use. In preferred embodiments, the invention relates to the field of eye health. In some embodiments, the invention relates to the prevention and treatment of macular degeneration by administering compounds disclosed herein. In some embodiments, the invention relates to compositions and methods of improving vision. |
US08318740B2 |
Compounds for protein kinase inhibition
Novel compound having the following formula: Also disclosed are a pharmaceutical compositions comprising the same, methods for treating cancer using the same, and methods for the synthesis of the same. The novel compounds of the present invention are found to inhibit protein kinases, especially Checkpoint kinase Chk1/Chk2. |
US08318738B2 |
Reverse-turn mimetics and method relating thereto
Conformationally constrained compounds that mimic the secondary structure of reverse-turn regions of biologically active peptides and proteins are disclosed. Such reverse-turn mimetic structures have utility over a wide range of fields, including use as diagnostic and therapeutic agents. Libraries containing the reverse-turn mimetic structures of this invention are also disclosed as well as methods for screening the same to identify biologically active members. The invention also relates to the use of such compounds for inhibiting or treating disorders modulated by Wnt-signaling pathway, such as cancer, especially colorectal cancer, restenosis associated with angioplasty, polycystic kidney disease, aberrant angiogenesis disease, rheumatoid arthritis disease, tuberous sclerosis complex, Alzheimer's disease, excess hair growth or loss, or ulcerative colitis. |
US08318735B2 |
2-aminothiazole-4-carboxylic amides as protein kinase inhibitors
The present invention relates to novel Anilinopiperazine Derivatives of formula (I), compositions comprising the Anilinopiperazine Derivatives, and methods for using the Anilinopiperazine Derivatives for treating or preventing a proliferative disorder, an anti-proliferative disorder, inflammation, arthritis, a central nervous system disorder, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral disease, a fungal infection, or a disorder related to the activity of a protein kinase. |
US08318730B2 |
Fused hetrocyclic compounds
This invention provides fused heterocyclic compounds, pharmaceutical compositions of the compounds, and methods of using the compounds for the treatment of, inter alia, IL-12 related disease and disorders. |
US08318727B2 |
Polo-like kinase inhibitors
Compounds of the following formula are provided for use with kinases: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds. |
US08318723B2 |
Pyrazine compounds, their use and methods of preparation
The invention provides compounds according to formula (I) their use and methods for preparation wherein A, X, Y, R1, R2 and R3 are defined herein. The compounds of the invention inhibit specific serine/threonine kinases involved in inflammatory processes and aberrant cell proliferation, and are thus useful for treating associated diseases and pathological conditions such as Pim kinase-mediated diseases and pathological conditions involving inflammation, including Chron's disease, inflammatory bowel disease, rheumatoid arthritis, and chronic inflammatory disease, or aberrant cell proliferation including various cancers. |
US08318720B2 |
Acrylamide derivatives as Fab I inhibitors
In part, the present invention is directed to antibacterial compounds. |
US08318718B2 |
Pyridine and pyrimidine derivatives as phosphodiesterase 10 inhibitors
Pyridine and pyrimidine compounds, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like. |
US08318717B2 |
Compounds modifying apoptosis
The present invention relates to compounds capable of inhibiting binding of the Smac protein to Inhibitors of apoptosis (IAPs). Such compounds are preferably capable of inhibiting IAP and thus may promote apoptosis or sensitize cells for apoptosis. The compounds may be used in the treatment of proliferative diseases, such as cancer. |
US08318712B2 |
Concentrated liquid thyroid hormone composition
This invention is directed generally to a liquid pharmaceutical composition comprising at least one thyroid hormone (particularly a composition further comprising at least one cyclodextrin compound), a process for making such a composition, and a method of using such a composition to treat a condition associated with impaired thyroid hormone function. |
US08318704B2 |
Modulation of neural stem cells and neural progenitor cells
The invention relates generally to methods of influencing central nervous system cells to produce progeny useful in the treatment of CNS disorders. More specifically, the invention includes methods of exposing a patient suffering from such a disorder to a reagent that modulates the proliferation, migration, differentiation and survival of central nervous system cells via S1P or LPA signaling. These methods are useful for reducing at least one symptom of the disorder. |
US08318700B2 |
Lung-targeted drugs
Methods and compositions are provided for treating lung diseases, including but not limited to infections and small cell and non-small cell lung cancer, by conjugating a drug of interest to glycerol ethers or glycerol phosphate ethers. |
US08318693B2 |
Compositions and methods for inhibiting expression of mutant EGFR gene
The invention relates to a double-stranded ribonucleic acid (dsRNA) targeting a mutant Epidermal Growth Factor Receptor (EGFR), and methods of using the dsRNA to inhibit expression of mutant EGFR. |
US08318692B2 |
Targeting PAX2 for the induction of DEFB1-mediated tumor immunity and cancer therapy
Provided is a method of treating cancer in a subject by inhibiting expression of PAX2. An example of a cancer treated by the present method is prostate cancer. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject. |
US08318691B2 |
Treatment of tumors with genetically engineered herpes virus
Disclosed are methods for treating cancer by administering an effective amount of a modified Herpes simplex virus. |
US08318686B2 |
Markers for pre-cancer and cancer cells and the method to interfere with cell proliferation therein
A novel family of human mitochondrial RNAs, referred to as chimeric RNAs, which are differentially expressed in normal, pre-cancer and cancer cells, are described. Oligonucleotides targeted to the chimeric RNAs are provided. The described oligonucleotides or their analogs can be used for cancer diagnostics and cancer therapy as well as for research. In one embodiment of this invention, these oligonucleotides hybridize with the sense or with the antisense mitochondrial chimeric RNAs, and the result of the hybridization is useful to differentiate between normal proliferating cells, pre-cancer cells and cancer cells. In another embodiment of the invention, the compositions comprise oligonucleotides that hybridize with the human chimeric RNAs resulting in cancer cell and pre-cancer cell death, while there is no effect in normal cells, constituting therefore, a novel approach for cancer therapy. |
US08318679B2 |
Trimerising module
The present invention relates to the design of trimeric polypeptides using polypeptide structural elements derived from the tetranectin protein family, and their use in rational de novo design and production of multi-functional molecules including the application of the multi-functional molecules in protein library technology, such as phage display technology, diagnostic and therapeutic systems, such as human gene therapy and imaging. The trimeric polypeptides being constructed as a monomer polypeptide construct comprising at least one tetranectin trimerising structural element (TTSE) which is covalently linked to at least one heterologous moiety, said TTSE being capable of forming a stable complex with two other TTSEs; or as an oligomer which is comprised of two monomer polypeptide constructs as mentioned above, and which comprises three TTSEs or a multiplum of three TTSEs, or which is comprised of three monomer polypeptide constructs. |
US08318678B2 |
Cosmetic compositions
The present invention generally features novel cosmetic skin and hair care compositions for enhancing the appearance of eyelashes and eyebrows. Specifically, the topical skin and hair care compositions of the invention contain a concentration of at least one of pentapeptide-17 tetrapeptide-12 that provide for thicker, longer and more voluminous appearing eyelashes and eyebrows. The cosmetic formulations of the invention may further include cosmetically acceptable vehicle(s) and/or other skin and hair conditioning agents. |
US08318673B2 |
Anti-hemorrhage medication pack
An anti-hemorrhage medication pack for administering an anti-hemorrhage drug, in particular for the treatment of hemorrhage caused by trauma in emergency situations comprises an active ingredient selected from the group comprising the 1-24 amino acid sequence of the adrenocorticotropic hormone (ACTH 1-24) and all its fragments and analogues, and analogues of fragments, with agonist activity on the MC4 melanocortin receptors, and all the synthesis agonists, including those with a nonpeptidic structure, of the MC4 melanocortin receptors. An auto-injector (1; 11) includes the drug for automatically injecting a patient with the drug. |
US08318664B2 |
Unacylated ghrelin fragments as therapeutic agent in the treatment of obesity
A method for treating obesity and more particularly a method for treating diet-induced obesity in a subject comprising administering to said subject an isolated unacylated ghrelin peptide as set forth in SEQ ID NO: 1, a fragment thereof or a cyclic fragment thereof such as a cyclic unacylated ghrelin fragment. The method being achievable without affecting the food intake of the subject. |
US08318661B2 |
Candidates against infection
The present invention relates to the use of plasminogen/plasmin and its derivatives as agents for enhancing host defense against infection or other infectious diseases. The invention also relates to a method for screening of compounds which enhance host defense against infection by evaluating the host defense against bacterial arthritis and spontaneous otitis media in an animal model. |
US08318650B2 |
Bis(hydroxyquinoline) metal complexes as bleach catalysts
Bis(hydroxyquinoline)-metal complexes and the use thereof as bleach catalysts are described. |
US08318649B2 |
Cleaning agents comprising a cyclic carbonate
The invention relates to machine dishwashing agents containing specific polycarbonate-, polyurethane-, and/or polyurea-polyorganosiloxane compounds or precursor compounds thereof of the reactive cyclic carbonate and urea type which help to avoid the formation of water spots and filming after the use of the agents and accelerate the drying of dishes. |
US08318648B2 |
Polyether-containing lubricant base stocks and process for making
A lubricant base stock is provided. The base stock is a polyether of a plurality of epoxidized olefin monomeric units. The polyether has 30 carbon atoms or more. There is also a process for making a polyether. |
US08318647B2 |
Production of polyol ester lubricants for refrigeration systems
A poly(neopentylpolyol) ester composition is produced by reacting a neopentylpolyol having the formula: wherein each R is independently selected from the group consisting of CH3, C2H5 and CH2OH and n is a number from 1 to 4, with at least one monocarboxylic acid having 2 to 15 carbon atoms in the presence of an acid catalyst and at an initial mole ratio of carboxyl groups to hydroxyl groups of greater than 0.5:1 to 0.95:1 to form a partially esterified poly(neopentylpolyol) composition. Then the partially esterified poly(neopentylpolyol) composition is reacted with additional monocarboxylic acid having 2 to 15 carbon atoms to form a final poly(neopentylpolyol) ester composition. |
US08318646B2 |
Lubricating oil composition
A lubricating oil composition comprising (A) an oil of lubricating viscosity in a major amount; and, (B) as an additive component in a minor amount, an oil-soluble zinc salt of a dithiophosphoric acid, the dithiophosphoric acid being the reaction product of phosphorus pentasulphide with a mixture of at least one first alcohol of the formula ROH where R is an aliphatic hydrocarbyl group having at least four carbon atoms or is an alkaryl group, and at least one second alcohol which is an ester of a polyhydric alcohol. |
US08318645B2 |
Lubricant composition
The lubricating oil composition of the invention includes a base oil composed of mineral oil and/or synthetic oil, an amine antioxidant (A-1) in an amount of 800 ppm or more as reduced to the total amount of nitrogen, and a compound containing phosphorus and/or sulfur (A-2). The invention provides a compressor oil which realizes thermal/oxidation stability, resistance to sludge formation, lubricity, long service life, and water separation at high levels. |
US08318636B2 |
Compositions and methods for improving rice growth and restricting arsenic uptake
Methods according to the invention administering one or more rice rhizosphere isolates to a plant, particularly a rice plant, to the seed of the plant, or to soil surrounding the plant in an amount effective to inhibit infection by a plant pathogen, particularly rice blast, to increase the biomass of the plant, and/or to decrease arsenic uptake by the plant. |
US08318634B2 |
Thermal transfer image-receiving sheets
The present invention relates to a resin for use in a thermal transfer image-receiving sheet which is excellent in dyeability with dyes and releasability of the sheet, a resin dispersion using the resin, and a thermal transfer image-receiving sheet. The resin for a thermal transfer image-receiving sheet is obtained by addition polymerizing and condensation polymerizing (a) raw monomers of a polyester, (b) a raw monomer of an addition polymer-based resin containing at least one compound selected from the group consisting of styrene and styrene derivatives and (c) at least one dually reactive monomer selected from the group consisting of acrylic acid, methacrylic acid and derivatives of these acids, wherein the raw monomers (a) of a polyester include an alcohol component containing 80 mol % or more of an alkyleneoxide adduct of 2,2-bis(4-hydroxyphenyl)propane. |
US08318632B2 |
Exhaust gas purification catalyst
An exhaust gas purification catalyst includes a substrate, and a first catalyst layer formed on the substrate, the first catalyst layer containing palladium and/or platinum and alumina doped with an alkaline-earth metal element. The exhaust gas purification catalyst has a correlation coefficient ρAl,AE given by the following formula of 0.75 or more: ρ Al , AE = C Al , AE σ Al σ AE . ( 1 ) |
US08318629B2 |
Platinum group metal-free catalysts for reducing the ignition temperature of particulates on a diesel particulate filter
A catalyzed diesel particulate filter (CDPF) and a method for filtering particulates from diesel engine exhaust are provided, where the catalyzed diesel particulate filter includes a substrate and a catalyst composition, where the catalyst composition contains at least one first component, at least one second component, and at least one third component, where the first component is at least one first component selected from the group consisting of cerium and a lanthanide and mixtures thereof, the at least one second component is selected from the group consisting of cobalt, copper, manganese and mixtures thereof; and the third component comprises strontium, where the first component, the second component, and the third component are in an oxide form after calcination. The catalyst on the catalyzed diesel particulate filter lowers the temperature at which particulates are removed from the CDPF by oxidizing the particulates on the filter. The catalyzed diesel particulate filter may also include a washcoat. Washcoats prepared from colloidal aluminum oxide may have higher surface areas and pore volumes loadings than washcoats containing aluminum oxide prepared from aluminum nitrate. |
US08318626B2 |
Internal and external donor compounds for olefin polymerization catalysts III
The present invention relates to solid catalyst components comprising titanium, magnesium, halogen and an internal electron donor compound containing at least one 1,8-naphthyl diester compound. The 1,8-naphthyl diester compounds include naphthalene-1,8-diyl dicycloalkanecarboxylate derivatives, dicycloalkenecarboxylate derivatives, 8-(cycloalkanecarbonyloxy)naphthalene-1-yl benzoate derivatives, and 8-(cycloalkenecarbonyloxy)naphthalene-1-yl benzoate derivatives. The present invention further relates to catalyst systems containing the catalyst solid components, organoaluminum compounds, and organosilicon compounds. The present invention also relates to methods of making the solid catalyst components and the catalyst systems, and methods of polymerizing or copolymerizing alpha-olefins using the catalyst systems. |
US08318620B2 |
Glass yarns capable of reinforcing organic and/or inorganic materials
The invention relates to a glass yarn capable of being obtained by a method consisting of mechanically drawing molten glass threads flowing from orifices disposed at the base of a die, of which the chemical composition is substantially free from boron oxide and comprises the following constituents within the limits defined hereinafter expressed in percentages by weight: SiO240 to 50 Al2O318 to 28 CaO4 to 15 MgO0 to 6 Na2O10 to 14 Na2O + K2O + Li2O13 to 20 It also relates to composites containing such yarns. |
US08318613B2 |
Composition for manufacturing SiO2 resist layers and method of its use
The present invention relates to compositions, which are useful for the generation of patterned or structured SiO2-layers or of SiO2-lines during the manufacturing process of semiconductor devices, and which are suitable for the application in inkjet operations. The present invention also relates to a modified process of manufacturing semiconductor devices taking advantage of these new compositions. |
US08318610B2 |
Method for thin film device with stranded conductor
Provided is a thin film device and an associated method of making a thin film device. For example, fabrication of an inverter thin film device is described. Moreover, a parallel spaced electrically conductive strips are provided upon a substrate. A functional material is deposited upon the conductive strips. A 3D structure is then provided upon the functional material, the 3D structure having a plurality of different heights, at least one height defining a first portion of the conductive strips to be bundled. The 3D structure and functional material are then etched to define a TFD disposed above the first portion of the conductive strips. The first portion of the conductive strips is bundled adjacent to the TFD. |
US08318607B2 |
Immersion lithography wafer edge bead removal for wafer and scanner defect prevention
A method of performing a single step/single solvent edge bead removal (EBR) process on a photolithography layer stack including a photoresist layer and a top coat layer using propylene glycol monomethyl ether acetate (PGMEA) or a mixture of PGMEA and gamma-butyrolactone (GBL) is disclosed. The single step/single solvent EBR process is compatible with organic and inorganic BARC layers. |
US08318606B2 |
Dielectric etching
An etchant for dielectrics, such as silicon dioxide, that leaves monocrystalline silicon surface exposed by the etchant free of etch damage, such as etch pits, when the etch is done in the presence of transition metals, such as copper, tungsten, titanium, gold, etc. The etchant comprises hydrofluoric acid and a source of halide anion, such as hydrochloric acid or a metal-halide. The etchant is useful in microelectromechanical system device fabrication and in deprocessing integrated circuits or the like. |
US08318605B2 |
Plasma treatment method for preventing defects in doped silicon oxide surfaces during exposure to atmosphere
Formation of BPSG surface defects upon exposure to atmosphere is prevented by a plasma treatment method for converting boron and/or phosphorus materials separated from silicon near the surface of the doped glass layer to gas phase compounds. The treatment plasma is generated from a treatment process gas containing one of (a) a fluorine compound or (b) a hydrogen compound. |
US08318603B2 |
Method of forming patterns for semiconductor device
Provided is a method of forming patterns for a semiconductor device in which fine patterns and large-width patterns are formed simultaneously and adjacent to each other. In the method, a first layer is formed on a substrate so as to cover a first region and a second region which are included in the substrate. Both a blocking pattern covering a portion of the first layer in the first region and a low-density large-width pattern covering a portion of the first layer in the second region are simultaneously formed. A plurality of sacrificial mask patterns are formed on the first layer and the blocking pattern in the first region. A plurality of spacers covering exposed sidewalls of the plurality of sacrificial mask patterns are formed. The plurality of sacrificial mask patterns are removed. The first layer in the first and second regions are simultaneously etched by using the plurality of spacers and the blocking pattern as etch masks in the first region and using the low-density large-width pattern as an etch mask in the second region. |
US08318596B2 |
Pillar structure having a non-planar surface for semiconductor devices
A conductive pillar for a semiconductor device is provided. The conductive pillar is formed such that a top surface is non-planar. In embodiments, the top surface may be concave, convex, or wave shaped. An optional capping layer may be formed over the conductive pillar to allow for a stronger inter-metallic compound (IMC) layer. The IMC layer is a layer formed between solder material and an underlying layer, such as the conductive pillar or the optional capping layer. |
US08318591B2 |
Nonvolatile memory device with dielectric layer formed on control gate sidewall along lateral direction
Patterns of a nonvolatile memory device include a semiconductor substrate that defines active regions extending in a longitudinal direction, an isolation structure formed between the active regions, a tunnel insulating layer formed on the active regions, a charge trap layer formed on the tunnel insulating layer, a first dielectric layer formed on the charge trap layer and the isolation structure, wherein the first dielectric layers is extended along a lateral direction, a control gate layer formed on the first dielectric layer, wherein the control gate layer is extended along the lateral direction, and a second dielectric layer formed on a sidewall of the control gate layer along the lateral direction and coupled to the first dielectric layer. |
US08318587B2 |
Method for manufacturing semiconductor device
It is an object to provide a method for manufacturing an SOI substrate in which reduction in yield can be suppressed while impurity diffusion into a semiconductor film is suppressed. A semiconductor substrate provided with an oxide film is formed by thermally oxidizing the surface of the semiconductor substrate. Plasma is generated under an atmosphere of a gas containing nitrogen atoms and plasma nitridation is performed on part of the oxide film, so that a semiconductor substrate in which an insulating film containing nitrogen atoms is formed over the oxide film is obtained. After bonding the insulating film containing nitrogen atoms and a glass substrate to each other, the semiconductor substrate is split, whereby an SOI substrate in which the insulating film containing nitrogen atoms, the oxide film, a thin semiconductor film are stacked in this order is formed. |
US08318585B2 |
Bonding method and bonding apparatus
To facilitate bonding of articles at a low temperature without degrading electrical contact between the articles.An oxide film reducing treatment with hydrogen radicals is carried out for surfaces of lead-out electrodes (5) and bump electrodes (6) on the lead-out electrodes (5) of a semiconductor chip (2) and surfaces of lead-out electrodes (8) of an intermediate substrate (3), and, after that, the bump electrodes (6) of the semiconductor chip (2) and the lead-out electrodes (8) of the intermediate substrate (3) are aligned with each other. After that, a pressure is applied to bond the bump electrodes (6) and the lead-out electrodes (8). |
US08318580B2 |
Isolating wire bonding in integrated electrical components
An electrical component includes a semiconductor layer having a first conductivity type and a interconnect layer disposed adjacent to a frontside of the semiconductor layer. At least one bond pad is disposed in the interconnect layer and formed adjacent to the frontside of the semiconductor layer. An opening formed from the backside of the semiconductor layer and through the semiconductor layer exposes at least a portion of the bond pad. A first region having a second conductivity type extends from the backside of the semiconductor layer to the frontside of the semiconductor layer and surrounds the opening. The first region can abut a perimeter of the opening or alternatively, a second region having the first conductivity type can be disposed between the first region and a perimeter of the opening. |
US08318578B2 |
Method of forming capacitors
A method of forming a capacitor includes providing material having an opening therein over a node location on a substrate. A shield is provided within and across the opening, with a void being received within the opening above the shield and a void being received within the opening below the shield. The shield comprises a nitride. Etching is conducted within the opening through the nitride-comprising shield. After the etching, a first capacitor electrode is formed within the opening in electrical connection with the node location. A capacitor dielectric and a second capacitor electrode are formed operatively adjacent the first capacitor electrode. Other aspects and implementations are contemplated. |
US08318577B2 |
Method of making a semiconductor device as a capacitor
Forming a capacitor structure includes forming a first dielectric layer over a conductive region, wherein the first dielectric layer has a first conductive layer at a top surface of the first dielectric layer; forming a first opening in the first dielectric layer over the conductive region, wherein the first opening exposes a first sidewall of the first conductive layer; forming a second conductive layer within the first opening, wherein the second conductive layer contacts the first sidewall of the first conductive layer; removing a portion of the second conductive layer from the bottom of the first opening; forming an insulating layer within the first opening; removing a portion of the insulating layer from the bottom of the first opening; extending the first opening through the first dielectric layer to expose the conductive region; and filling the first opening with a conductive material, wherein the conductive material contacts the conductive region. |
US08318576B2 |
Decoupling capacitors recessed in shallow trench isolation
A semiconductor process and apparatus provide a shallow trench isolation capacitor structure that is integrated in an integrated circuit and includes a bottom capacitor plate that is formed in a substrate layer below a trench opening, a capacitor dielectric layer and a recessed top capacitor plate that is covered by an STI region and isolated from cross talk by a sidewall dielectric layer. |
US08318574B2 |
SOI trench DRAM structure with backside strap
In one exemplary embodiment, a semiconductor structure including: a SOI substrate having of a top silicon layer overlying an insulation layer, the insulation layer overlies a bottom silicon layer; a capacitor disposed at least partially in the insulation layer; a device disposed at least partially on the top silicon layer, where the device is coupled to a doped portion of the top silicon layer; a backside strap of first epitaxially-deposited material, at least a first portion of the backside strap underlies the doped portion of the top silicon layer, the backside strap is coupled to the doped portion of the top silicon layer at a first end of the backside strap and to the capacitor at a second end of the backside strap; and second epitaxially-deposited material that at least partially overlies the doped portion of the top silicon layer, the second epitaxially-deposited material further at least partially overlies the first portion. |
US08318572B1 |
Inexpensive electrode materials to facilitate rutile phase titanium oxide
This disclosure provides a method of fabricating a semiconductor stack and associated device, such as a capacitor and DRAM cell. In particular, a bottom electrode has a material selected for lattice matching characteristics. This material may be created from a relatively inexpensive metal oxide which is processed to adopt a conductive, but difficult-to-produce oxide state, with specific crystalline form; to provide one example, specific materials are disclosed that are compatible with the growth of rutile phase titanium dioxide (TiO2) for use as a dielectric, thereby leading to predictable and reproducible higher dielectric constant and lower effective oxide thickness and, thus, greater part density at lower cost. |
US08318570B2 |
Enhancing MOSFET performance by optimizing stress properties
A device and method for improving performance of a transistor includes gate structures formed on a substrate having a spacing therebetween. The gate structures are formed in an operative relationship with active areas fainted in the substrate. A stress liner is formed on the gate structures. An angled ion implantation is applied to the stress liner such that ions are directed at vertical surfaces of the stress liner wherein portions of the stress liner in contact with the active areas are shielded from the ions due to a shadowing effect provided by a height and spacing between adjacent structures. |
US08318569B2 |
Forming memory cells comprising impurity doping regions along edges of less than 1F spacing
Provided are methods of forming a semiconductor device, the method including: forming an insulation region on a substrate region, and an active region on the insulation region; patterning the active region to form an active line pattern; forming a gate pattern to surround an upper portion and lateral portions of the active line pattern; separating the gate pattern into a plurality of sub-gate regions, and separating the active line pattern into a plurality of sub-active regions, in order to form a plurality of memory cells that are each formed of the sub-active region and the sub-gate region and that are separated from one another; and forming first and second impurity doping regions along both edges of the sub-active regions included in each of the plurality of the memory cells, wherein the forming of the first and second impurity doping regions comprises doping lateral portions of the sub-active regions via a space between the memory cells. |
US08318563B2 |
Growth of group III nitride-based structures and integration with conventional CMOS processing tools
A method includes forming a non-continuous epitaxial layer over a semiconductor substrate. The substrate includes multiple mesas separated by trenches. The epitaxial layer includes crystalline Group III nitride portions over at least the mesas of the substrate. The method also includes depositing a dielectric material in the trenches. The method could also include forming spacers on sidewalls of the mesas and trenches or forming a mask over the substrate that is open at tops of the mesas. The epitaxial layer could also include Group III nitride portions at bottoms of the trenches. The method could further include forming gate structures, source and drain contacts, conductive interconnects, and conductive plugs over at least one crystalline Group III nitride portion, where at least some interconnects and plugs are at least partially over the trenches. The gate structures, source and drain contacts, interconnects, and plugs could be formed using standard silicon processing tools. |
US08318556B2 |
Method and system for continuous line-type landing polysilicon contact (LPC) structures
A method for making contact landing pad structures in a semiconductor integrated circuit device includes forming an isolation region and forming active regions in the semiconductor substrate. The active regions are separated by the isolation region, and each of the active regions includes one or more contact regions. The method includes forming a raised structure overlying the isolation region and disposed between a first and second contact regions. The method includes depositing a cap layer and forming an interlayer dielectric layer overlying the cap layer. The method includes depositing a photoresist layer overlying the interlayer dielectric layer and uses a mask pattern to selectively remove a portion of the photoresist layer to form a line type opening, which exposes a portion of the interlayer dielectric layer overlying at least the first and second contact regions. The method deposits a conductive fill material and performs a planarization process to form multiple conductive landing contact pads. |
US08318552B2 |
Method for forming gate structures
A process for forming gate structures is described. A web comprises a substrate, a plurality of conductive elements disposed on the substrate, and a conductive anodization bus. The web is moved through an anodization station to form a plurality of gate structures comprising a plurality of gate dielectrics adjacent to a plurality of gate electrodes. A process for forming electronic devices further providing a semiconductor, a source electrode, and a drain electrode is described. |
US08318546B2 |
Thermal management of electronic devices
Thermal management is provided for a device. The device may include a substrate having a mounting area on a first surface of the substrate. The device may also include first thermal vias extending from the mounting area to at least an interior of the substrate. The device may also include at least one thermal plane substantially parallel to the first surface of the substrate, the at least one thermal plane being in thermal contact with at least one of the first thermal vias. The device may also include a heat sink attachment area, and second thermal vias extending from the heat sink attachment area to the interior of the substrate, the at least one thermal plane being in thermal contact with the second thermal vias. |
US08318542B2 |
Contact spring application to semiconductor devices
A contact spring applicator is provided which includes an applicator substrate, a removable encapsulating layer and a plurality of contact springs embedded in the removable encapsulating layer. The contact springs are positioned such that a bond pad on each contact spring is adjacent to an upper surface of the removable encapsulating layer. The contact spring applicator may also include an applicator substrate, a release layer, a plurality of unreleased contact springs on the release layer and a bond pad at an anchor end of each contact spring. The contact spring applicators apply contact springs to an integrated circuit chip, die or package or to a probe card by aligning the bond pads with bond pad landings on the receiving device. The bond pads are adhered to the bond pad landings. The encapsulating or release layer is then removed to separate the contact springs from the contact spring applicator substrate. |
US08318536B2 |
Utilizing aperture with phase shift feature in forming microvias
A method, comprises drilling a set of one or more microvias in a semiconductor package with an aperture, wherein drilling the set of microvias comprises to use an aperture that has a phase shift region to reduce a spot size of a drilling beam that is used to form the set of microvias. |
US08318532B2 |
Enhancing performance characteristics of organic semiconducting films by improved solution processing
Improved processing methods for enhanced properties of conjugated polymer films are disclosed, as well as the enhanced conjugated polymer films produced thereby. Addition of low molecular weight alkyl-containing molecules to solutions used to form conjugated polymer films leads to improved photoconductivity and improvements in other electronic properties. The enhanced conjugated polymer films can be used in a variety of electronic devices, such as solar cells and photodiodes. |
US08318525B2 |
Gas sensing device
A device for sensing a gas comprises a plastics housing (106, 107) moulded in situ around at least one portion of a conducting lead frame (100), the housing defining an enclosure (113) and being provided with means for enabling gas flow into the enclosure. A gas sensitive element (114) within the enclosure (113) is mounted to the conducting lead frame (100). The conducting lead frame (100) comprises connection leads which are accessible through, and at least partially encapsulated by, the wall of the housing. |
US08318522B2 |
Surface passivation techniques for chamber-split processing
Surface passivation techniques for chamber-split processing are described. A method includes forming a first Group III-V material layer above a substrate, the first Group III-V material layer having a top surface. A passivation layer is deposited on the top surface of the Group III-V material layer. The passivation layer is removed. Subsequently, a second Group III-V material layer is formed above the first Group III-V material layer. |
US08318521B2 |
Organic light emitting display and method of manufacturing the same
A top emission organic light emitting display and a method of manufacturing the same. The organic light emitting display includes a substrate, a plurality of thin film transistors (TFT) on the substrate, a plurality of first electrodes coupled to the plurality of TFTs, auxiliary electrodes having a mesh structure defining areas where the plurality of first electrodes are located, a pixel defining layer on a substantially entire area of the substrate and patterned to expose the first electrodes and the auxiliary electrodes, an organic light emission layer on the substantially entire area of the substrate including the exposed first electrodes and auxiliary electrodes, and second electrodes on the organic light emission layer. Steps are formed at lower parts of the auxiliary electrodes, and the second electrodes are coupled to the auxiliary electrodes through contact regions in which the auxiliary electrodes are exposed due to the steps. |
US08318514B2 |
LED package, and mold and method of manufacturing the same
The present disclosure provides a light emitting diode (LED) package, which includes a first substrate with electrodes disposed on a top thereof and a second substrate with an LED chip disposed on a top thereof. The LED chip is connected with the electrodes via wires. A first package layer is disposed on the top of the first substrate to cover the wires and electrodes. A fluorescent layer is disposed on the top of the second substrate to cover the LED chip. The present disclosure also provides a mold and a method of manufacturing the LED package. |
US08318506B2 |
Dialysis adapter cell and method of release testing of a disperse dosage form
A dialysis adapter cell includes a housing comprising a plurality of pillars extending between and attached to a top plate and a bottom plate to form a hollow receptacle, wherein the top plate comprises an aperture configured to provide access to the hollow receptacle; a dialysis membrane disposed about the housing and sealingly engaged to the top plate and the bottom plate; and a platform in physical communication with the bottom plate and configured to position the dialysis adapter cell in a sample holder of a United States Pharmacopoeia dissolution apparatus 4 flow-through cell. |
US08318504B2 |
MRP2 efflux pathway prognostic method
In one aspect a method of determining the functional activity of the MRP2 and/or MRP3 efflux pathway of a human or animal subject, comprises: (i) determining the level of a bile acid derivative in the blood of said human or animal subject at a predetermined time interval after introducing an amount of the bile acid derivative into the subject; and (ii) using the determination obtained in step (i) to indicate the functional activity of the MRP2 and/or MRP3 efflux pathway of the subject. |
US08318499B2 |
System for managing inventories of reagents
A system for managing the inventory of reagents for a laboratory automation system. The system for managing the inventory of reagents comprises a controller, software for the controller, and a refrigerator capable of refrigerating reagents, detecting the presence or absence of reagents in the refrigerator, and detecting the location of reagents in the refrigerator. The system for managing the inventory of reagents is connected to a laboratory automation system. The laboratory automation system comprises at least one clinical analyzer. A typical system for managing inventories of reagents includes an operator interface for the loading of boxes of reagents and other supplies, radio frequency identification system for identification of inventory and tracking, robotic mechanisms for loading containers onto the track system and removing containers from the track system, de-capping equipment, refrigeration equipment, and information technology connections to laboratory analyzers and vendors. |
US08318497B2 |
Reversible, parallel and multitask cloning method and kit
The present invention is related to a reversible, parallel and/or multitask cloning method and kit, which improve the cloning of (preferably multiple) genetic element(s) in a nucleic acid construct such as vector or in chromosome of a cell and the rapid and efficient selection of said construct with a correct integration of said genetic element(s) either in vitro or in vivo. |
US08318496B2 |
Compounds and methods for improving cellular uptake of oligomeric compounds
The present invention provides method of optimizing the efficacy and potency of antisense drugs. In certain embodiments, the invention provides assays useful for determining favorable oligonucleotide characteristics and excipeints for improved cellular uptake. |
US08318494B2 |
Genetic material and chromosomal processing and manipulation methods
The presently claimed invention applies to a genetic material processing and manipulation method and related product. The claimed invention relates to a method for changing the inherited characteristics of a cell through chromosome processing treatment. In a preferred embodiment, ‘genomic surgery’ is applied to source genetic material 101. Micro-beam cutting takes place on target genetic material 103, which is moved by way of micro-beam transport to a destination location adjacent to desired target genetic material 105. Source and target genetic material are welded during a micro-beam welding step, resulting in a combined or new chromosome combination 125. The combined or new chromosome combination 125 is transferred into receptor cell by three ways. The presently claimed invention provides a high quality alternate approach to directed genetic recombination without requiring the use of restriction enzymes and is used for chromosomal repair, removal of defects and new organism creation. |
US08318492B2 |
Method for determining the cell culture history of a cell unit labeled with more than one type of tag
The present invention relates in one aspect to a method for determining the cell culture history of a cell unit labelled with more than one type of tag comprising the steps of: (a) measuring one or more parameters of each tag that is used to label the cell unit; (b) identifying each tag in the cell unit; and (c) correlating the identity of each tag to the identity of the cell unit and/or the specific cell culture conditions to which the cell unit has been exposed. |
US08318491B2 |
Method of differentiating hematopoietic stem cells into natural killer cells using YC-1 or IL-21
The present invention relates to an agent for differentiating hematopoietic stem cells into natural killer cells and a method for the differentiation, more precisely an agent for differentiating hematopoietic stem cells into natural killer cells comprising YC-I [3-(5′-hydroxymethyl-2′-furyl)-1-benzylindazole] or IL-21 (Interleukin-21) as an active ingredient and a method for differentiating hematopoietic stem cells into natural killer cells using the same. The YC-I and IL-21 regulate the differentiation of hematopoietic stem cells into natural killer cells and increase the killing activity of NK cells. Therefore, the agent for NK cell differentiation of the present invention can be effectively used for cell therapy for the treatment of cancer by regulating the differentiation of hematopoietic stem cells into natural killer cells having tumor cell killing activity. |
US08318487B2 |
Materials and methods relating to the production and maintenance of cell lines
The invention provides methods for maintaining cell lines from primary cells, i.e. non-transformed cells, using expression of the signal transducer of activation and transcription (STAT). The methods are particularly suitable for the maintenance of B-cells. |
US08318484B2 |
Isolated renal cells and uses thereof
The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations. |
US08318482B2 |
VCP-based vectors for algal cell transformation
Provided herein are exemplary vectors for transforming algal cells. In exemplary embodiments, the vector comprises a Violaxanthin-chlorophyll a binding protein (Vcp) promoter driving expression of an antibiotic resistance gene in an algal cell. Embodiments of the invention may be used to introduce a gene (or genes) into the alga Nannochloropsis, such that the gene(s) are expressed and functional. This unprecedented ability to transform Nannochloropsis with high efficiency makes possible new developments in phycology, aquaculture and biofuels applications. |
US08318472B2 |
Optimized nucleic acid sequences for the expression of VB4-845
An optimized nucleic acid sequence encoding the immunoconjugate VB4-845 is disclosed. Modifications to the original VB4-845 nucleic acid sequence include optimization of the sequences encoding the VH region, VL region, linkers and pseudomonas exotoxin A. The modifications improved the yield of VB4-845 in an Escherichia coli expression system. |
US08318470B2 |
Subtilases
The present invention relates to novel JP170 like subtilases from wild-type bacteria, hybrids thereof and to methods of construction and production of these proteases. Further, the present invention relates to use of the claimed subtilases in detergents, such as a laundry or an automatic dishwashing detergent. |
US08318467B2 |
Inhibitors of GSK-3 and crystal structures of GSK-3β protein and protein complexes
The present invention relates to inhibitors of GSK-3 and methods for producing these inhibitors. The invention also provides pharmaceutical compositions comprising the inhibitors and methods of utilizing those compositions in the treatment and prevention of various disorders, such as diabetes and Alzheimer's disease. In addition, the invention relates to molecules or molecular complexes which comprise binding pockets of GSK-3β or its homologues. The invention relates to a computer comprising a data storage medium encoded with the structure coordinates of such binding pockets. The invention also relates to methods of using the structure coordinates to solve the structure of homologous proteins or protein complexes. The invention relates to methods of using the structure coordinates to screen for and design compounds that bind to GSK-3β protein or homologues thereof. The invention also relates to crystallizable compositions and crystals comprising GSK-3β protein or GSK-3β protein complexes. |
US08318464B2 |
Biofuel production
Methods, enzymes, recombinant microorganism, and microbial systems are provided for converting polysaccharides, such as those derived from biomass, into suitable monosaccharides or oligosaccharides, as well as for converting suitable monosaccharides or oligosaccharides into commodity chemicals, such as biofuels. Commodity chemicals produced by the methods described herein are also provided. Commodity chemical enriched, refinery-produced petroleum products are also provided, as well as methods for producing the same. |
US08318463B2 |
Δ8 desaturases and their use in making polyunsaturated fatty acids
The present invention relates to Δ8 desaturase genes, which have the ability to convert eicosadienoic acid (EDA; 20:2 ω-6) to dihomo-γ-linolenic acid (DGLA; 20:3 ω-6) and/or eicosatrienoic acid (ETrA; 20:3 ω-3) to eicosatetraenoic acid (ETA; (20:3 ω-3). Isolated nucleic acid fragments and recombinant DNA constructs comprising such fragments encoding Δ8 desaturases along with a method of making long-chain polyunsaturated fatty acids (PUFAs) using these Δ8 desaturases in oleaginous yeast are disclosed. |
US08318461B2 |
Enzyme compositions for the improved enzymatic hydrolysis of cellulose and methods of using same
A process for the enzymatic hydrolysis of cellulose to produce a hydrolysis product comprising glucose from a pretreated lignocellulosic feedstock and enzymes for use in the process are provided. The process comprises hydrolyzing an aqueous slurry of a pretreated lignocellulosic feedstock with cellulase enzymes, one or more than one β-glucosidase enzyme and a binding agent for binding the β-glucosidase enzyme to fiber solids present in the aqueous slurry. During the hydrolysis, both the cellulase enzyme and β-glucosidase enzyme bind to the fiber solids. The hydrolysis is performed in a solids-retaining hydrolysis reactor so that unhydrolyzed fiber solids and bound enzyme are retained in the reactor longer than the aqueous phase of the slurry. |
US08318460B2 |
Haplotype analysis
The present invention provides an efficient way for high throughput haplotype analysis. Several polymorphic nucleic acid markers, such as SNPs, can be simultaneously and reliably determined through multiplex PCR of single nucleic acid molecules in several parallel single molecule dilutions and the consequent statistical analysis of the results from these parallel single molecule multiplex PCR reactions results in reliable determination of haplotypes present in the subject. The nucleic acid markers can be of any distance to each other on the chromosome. In addition, an approach wherein overlapping DNA markers are analyzed can be used to link smaller haplotypes into larger haplotypes. Consequently, the invention provides a powerful new tool for diagnostic haplotyping and identifying novel haplotypes. |
US08318459B2 |
Glucosyl stevia composition
Glucosyl stevia compositions are prepared from steviol glycosides of Stevia rebaudiana Bertoni. The glucosylation was performed by cyclodextrin glucanotransferase using the starch as source of glucose residues. The short-chain glucosyl stevia compositions were purified to >95 % content of total steviol glycosides. The compositions can be used as sweetness enhancers, flavor enhancers and sweeteners in foods, beverages, cosmetics and pharmaceuticals. |
US08318453B2 |
Conversion systems for biomass
The efficient production of ethanol from low-cost biomass (e.g., corn, sugar beets, sugar cane, switchgrass and/or paper) has become increasingly important in making ethanol competitive with gasoline and decreasing the United States' dependence on foreign oil. For example, to reduce the cost of transporting biomass to ethanol production facilities, mobile systems for producing ethanol from biomass are provided. Also provided are small-scale ethanol production facilities. For example, instead of transporting biomass to the production facility, the facility is transported to the biomass or is located nearby the source of the biomass. The ethanol production facilities or components thereof may be transported via land, water, or air. Production of other products, such as hydrocarbons, natural gas, hydrogen gas, plastics, polymers, and proteins, can also be made by the methods and facilities. Any product described herein can be made in finished form or un-finished form and moved, e.g., to a fixed facility, e.g., fixed production facility. |
US08318449B2 |
Method of measuring the activity of lipid-modified enzyme
It is intended to provide an assay method whereby the activity of a lipid-modifying enzyme can be conveniently measured over a wide range and a drug capable of controlling a lipid-modifying enzyme with the use of this assay method. The above problem can be solved by, for example, a method of measuring the activity of a lipid-modifying enzyme which comprises the steps of (I) preparing a lipid micelle containing a biotinylated lipid and a substrate for the lipid-modifying enzyme; (II) bringing the lipid micelle prepared in the above step (I) into contact with the lipid-modifying enzyme; and (III) evaluating the activity of the lipid-modifying enzyme by applying an evaluation method using the proximity effect to the product obtained in the above step (II). |
US08318447B2 |
Use of bitter taste receptor to screen for compounds that offset the bitter taste of chlorogenic lactone containing coffee compositions
The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds, i.e., chlorogenic lactone compounds that contribute at least partially to the bitter taste of many coffee beverages. The present invention further relates to the use of these receptors in assays for identifying ligands that modulate the activation of these taste receptors by chlorogenic lactones and related compounds and which may be used as additives and/or removed from foods, beverages and medicinals in order to modify (block) T2R-associated bitter taste. A preferred embodiment is the use of the identified compounds as additives in coffee and coffee-flavored foods, beverages and medicinals. |
US08318443B2 |
Reagent for detecting an analyte
A reagent for use in detecting an analyte comprises a fluorescent energy donor and an energy acceptor, wherein the energy acceptor is of the general formula: and wherein the distance between the energy donor and the energy acceptor of the reagent is capable of modulation by a suitable analyte to be detected. |
US08318441B2 |
Fibrinogen alpha and hemoglobin polypeptides as cancer markers
The present invention provides methods of detecting cancer using biomarkers. |
US08318438B2 |
Aptamer-based assays
We describe examples using aptamers for capturing and reporting the presence of a target, such as a pathogen. Examples described here include a set of aptamers that are specific to F. tularensisis. Other examples described here include an Aptamer-Linked Immobilized Sorbent Assay (ALISA) and dot blot assay. An example of a method provided here comprises: providing a set of DNA sequences that exhibit high binding affinity to target antigen, placing the DNA sequences in a sandwich aptamer-linked immobilized sorbent assay (ALISA), contacting the DNA sequences with a sample, and detecting whether the target is present in the sample. Some alternative implementations may include dot blots and different reporters. Quantum dot sandwich assays and quantum dot de-quenching reporters can be used. |
US08318433B2 |
Methods and compositions for tagging and identifying polynucleotides
The invention provides methods and compositions for attaching oligonucleotide tags to polynucleotides for the purpose of carrying out analytical assays in parallel and for decoding the oligonucleotide tags of polynucleotides selected in such assays. Words, or subunits, of oligonucleotide tags index submixtures in successively more complex sets of submixtures (referred to herein as “tiers” of submixtures) that a polynucleotide goes through while successive words are added to a growing tag. By identifying each word of an oligonucleotide tag, a series of submixtures is identified including the first submixture that contains only a single polynucleotide, thereby providing the identity of the selected polynucleotide. The analysis of the words of an oligonucleotide tag can be carried out in parallel, e.g. by hybridization of the oligonucleotide tag to its tag complement on an addressable array; or such analysis can be carried out serially by successive hybridizations of labeled word complements. |
US08318428B2 |
Real-time PCR point mutation assays for detecting HIV-1 resistance to antiviral drugs
Disclosed are compositions including primers and probes, which are capable of interacting with the disclosed nucleic acids, such as the nucleic acids encoding the reverse transcriptase or protease of HIV as disclosed herein. Thus, provided is an oligonucleotide comprising any one of the nucleotide sequences set for in SEQ ID NOS:1-89, and 96-104. Also provided are the oligonucleotides consisting of the nucleotides as set forth in SEQ ID NOS:1-89, and 96-104. Each of the disclosed oligonucleotides is a probe or a primer. Also provided are mixtures of primers and probes and for use in RT-PCR and primary PCR reactions disclosed herein. Provided are methods for the specific detection of several mutations in HIV. Mutations in both the reverse transcriptase and the protease of HIV can be detected using the methods described herein. |
US08318427B2 |
Use of acid scavengers for the synthesis of standard length and long-mer nucleic acid arrays
Protective groups which may be cleaved with an activatable deprotecting reagents are employed to achieve a highly sensitive, high resolution, combinatorial synthesis of pattern arrays of diverse polymers. In preferred embodiments of the instant invention, the activatable deprotecting reagent is a photoacid generator and the protective groups are DMT for nucleic acids and tBOC for amino acids. This invention has a wide variety of applications and is particularly useful for the solid phase combinatorial synthesis of polymers. |
US08318425B2 |
Inhibition of HIV-1 replication by disruption of the processing of the viral capsid-spacer peptide 1 protein
Inhibition of HIV-1 replication by disrupting the processing of the viral Gag capsid (CA) protein (p24) from the CA-spacer peptide 1 (SP1) protein precursor (p25) is disclosed. Amino acid sequences containing a mutation in the Gag p25 protein, with the mutation resulting in a decrease in the inhibition of processing of p25 to p24 by dimethylsuccinyl betulinic acid or dimethylsuccinyl betulin, polynucleotides encoding such mutated sequences and antibodies that selectively bind such mutated sequences are also included. Methods of inhibiting, inhibitory compounds and methods of discovering inhibitory compounds that target proteolytic processing of the HIV Gag protein are included. In one embodiment, such compounds inhibit the interaction of the HIV protease enzyme with Gag by binding to the Gag proteolytic cleavage site rather than to the protease enzyme. In another embodiment, viruses or recombinant proteins that contain mutations in the region of the Gag proteolytic cleavage site can be used in screening assays to identify compounds that target proteolytic processing. |
US08318424B2 |
High-throughput RNA structure analysis
The presently disclosed subject matter relates to technology and methods for analyzing the structure of RNA molecules. More particularly, the presently disclosed subject matter is directed to methods of, compositions for, and computer program products for RNA structure analysis through alkoxide-selective 2′-hydroxyl acylation analyzed by primer extension. |
US08318423B2 |
Methods and compositions for detecting rhinoviruses
The invention provides methods and compositions for rapid, sensitive, and highly specific nucleic acid-based (e.g., DNA based) detection of human rhinovirus (HRV) in a sample. In general, the methods involve detecting a target nucleic acid having a target sequence of a conserved 5′ untranslated region of the HRV genome. The invention also features compositions, including primers, probes, and kits, for use in the methods of the invention. |
US08318421B2 |
Hepatitis-C virus testing
New styles of hepatitis C virus (HCV), referred to as HCV-3 and HCV-4, have been identified and sequenced. Antigenic regions of HCV-2, HCV-3 and HCV-4 polypeptides have been identified. Immunoassays for HCV and antibodies thereto are described, which allow more complete screening of blood samples for HCV, and allow HCV genotyping. |
US08318419B2 |
Antiviral screening method to identify inhibitors of phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2] binding to the HIV gag matrix (MA) protein
The present invention provides for testing methods to determine an effective testing agent that affects the activity of the HIV Gag protein at the plasma membrane of a cell, and specifically, effecting changes in the structural conformation of at least one fatty acid of PI(4,5)P2, a member of a family of differentially phosphorylated phosphatidylinositides, wherein inhibition of the extension of such fatty acid into the MA domain of the Gag protein reduces binding of Gag to the plasma membrane, thereby inhibiting virus particle assembly and subsequent replication of the HIV virus. |
US08318418B2 |
Determination of testosterone by mass spectrometry
Provided are methods for determining the presence or amount of testosterone in a test sample, comprising ionizing all or a portion of the testosterone present in the sample to produce one or more testosterone ions that are detectable in a mass spectrometer. All or a portion of the testosterone present in the sample is ionized to produce one or more testosterone ions, which may be isolated and fragmented to produce precursor ions. A separately detectable internal testosterone standard can be provided in the sample. In a preferred embodiment, the reference is 2,2,4,6,6-d5 testosterone. |
US08318408B2 |
Method of forming patterns of semiconductor device
In a method of forming patterns of a semiconductor device, a semiconductor substrate defining photoresist patterns formed over a target etch layer is provided. An auxiliary layer is formed over the semiconductor substrate and the photoresist patterns. The auxiliary layer formed on a surface of the photoresist patterns is denatured into first auxiliary patterns. A photoresist film is formed over the semiconductor substrate, the first auxiliary patterns, and the auxiliary layer. The auxiliary layer formed below the photoresist film is denatured into a second auxiliary pattern. Here, the auxiliary layer remains only between the photoresist patterns. Etch mask patterns, including the photoresist patterns and the auxiliary layer, are formed by removing the photoresist film and the first and second auxiliary patterns. |
US08318404B2 |
Salt and photoresist composition containing the same
A salt represented by the formula (a1): wherein Q1 and Q2 each independently represent a fluorine atom or a C1-C4 perfluoroalkyl group, X1 represents —CO—O—Xa1— or —CH2—O—Xa2— wherein Xa1 and Xa2 independently each represent a C1-C15 alkylene group and one or more —CH2— in the alkylene group can be replaced by —O— or —CO—, Y1 represents a C3-C36 alicyclic hydrocarbon group or a C6-C24 aromatic hydrocarbon group, and the alicyclic hydrocarbon group and the aromatic hydrocarbon group can have one or more substituents, and one or more —CH2— in the alicyclic hydrocarbon group can be replaced by —O— or —CO—, and Z+ represents an organic cation. |
US08318395B2 |
Dibenzoanthracene compound and organic light emitting device having the same
Provided is a novel dibenzo[a,c]anthracene compound having substituents, which can be used in an organic light emitting device. |
US08318391B2 |
Process window signature patterns for lithography process control
A method for identifying process window signature patterns in a device area of a mask is disclosed. The signature patterns collectively provide a unique response to changes in a set of process condition parameters to the lithography process. The signature patterns enable monitoring of associated process condition parameters for signs of process drift, analyzing of the process condition parameters to determine which are limiting and affecting the chip yields, analyzing the changes in the process condition parameters to determine the corrections that should be fed back into the lithography process or forwarded to an etch process, identifying specific masks that do not transfer the intended pattern to wafers as intended, and identifying groups of masks that share common characteristics and behave in a similar manner with respect to changes in process condition parameters when transferring the pattern to the wafer. |
US08318389B2 |
Image sensor photo mask and apparatus
A method for fabricating an image sensor includes forming an insulation layer over a substrate in a logic circuit region and a pixel region, forming a photoresist over the insulation layer, patterning the photoresist to form a photoresist pattern where the insulation layer in the pixel region is exposed and the insulation layer in the logic circuit region is not exposed, wherein a thickness of the photoresist pattern is gradually decreased in an interfacial region between the pixel region and the logic circuit region in a direction of the logic circuit region to the pixel region, and performing an etch back process over the insulation layer and the photoresist pattern in conditions that an etch rate of the photoresist pattern are substantially the same as that of the insulation layer. |
US08318388B2 |
Mask blank providing system, mask blank providing method, mask blank transparent substrate manufacturing method, mask blank manufacturing method, and mask manufacturing method
A mask blank manufacturing department manufactures a mask blank by forming a thin film to be a mask pattern on a mask blank transparent substrate. When providing the mask blank to a mask manufacturing department, the mask blank manufacturing department provides optical characteristic information (transmittance variation) of the mask blank transparent substrate and optical characteristic information (transmittance variation and/or phase difference variation) of the mask blank to the mask manufacturing department. The optical characteristic information of the mask blank transparent substrate is provided to the mask blank manufacturing department from a materials processing department that manufactures mask blank transparent substrates. |
US08318386B2 |
Fabrication of nanostructured devices
Embodiments of the invention relate to methods useful in the fabrication of nanostructured devices for optics, energy generation, displays, consumer electronics, life sciences and medicine, construction and decoration. Instead of nanostructuring using colloids of particles, special vacuum deposition methods, laser interference systems (holography), and other low-throughput limited surface area techniques, we suggest to use nanotemplate created by novel nanolithography method, “Rolling mask” lithography. This method allows fast and inexpensive fabrication of nanostructures on large areas of substrate materials in conveyor-type continuous process. Such nanotemplate is then used for selective deposition of functional materials. One of embodiments explains deposition of functional materials in the exposed and developed areas of the substrate. Another embodiment uses selective deposition of the functional material on top of such template. Alternatively, nanotemplate is deposited and patterned on functional material, and then used as an etch mask to transfer nanostructure into the functional material using dry or wet etching process. |
US08318384B2 |
Anode catalyst and methods of making and using the same
The present disclosure relates to an ion conductive material useful as an anode catalyst comprising LaCrO3, a vanadium oxide (VOx) and a solid electrolyte, and methods of making the same. The catalysts are useful in solid oxide fuels cells and, in particular, using impure hydrogen. |
US08318383B2 |
Fuel cell reaction layer
Disclosed is a fuel cell reaction layer which is excellent in durability and heat resistance while having a low operation temperature. In addition, supply of an oxygen gas to the fuel cell reaction layer is hardly disturbed. Also disclosed are a fuel cell and a method for producing such a fuel cell reaction layer. Specifically disclosed is a fuel cell reaction layer wherein a mixed conductive catalyst is used. The mixed conductive catalyst includes a conductive carrier composed of an electron conductor formed of carbon and a proton conductor formed of an inorganic material. The electron conductor is an inorganic material comprising a polymerized and carbonized organic monomer: the proton conductor is an inorganic material, and the electron conductor and the proton conductor are bonded together. In addition, a water-repellent carbon is further blended in this fuel cell reaction layer. |
US08318382B2 |
Fuel cell electrode containing proton conductive inorganic oxide
According to one embodiment, a catalyst layer of an electrode for a fuel cell has a proton conductive inorganic oxide containing an oxide superacid compound. The compound contains an element X (Titanium, Zirconium, Silicon, Tin, Hafnium, Germanium, Gallium, Indium, Cerium, Niobium or Aluminum) and an element Y (Tungsten, Molybdenum, Chromium, Boron or Vanadium). The catalyst layer also contains a reduction-oxidation metal catalyst or a carrier carrying a reduction-oxidation metal catalyst. |
US08318381B2 |
Device and method for enhanced air circulation
A wireless communication device (200) and method (300) adapted to prolong the useful life of an energy storage device is disclosed. In its simplest form, it can include: detecting (310) a first threshold of an energy conversion module comprising at least one of a temperature threshold, oxygen threshold, voltage, a current threshold, a power threshold and moisture threshold; sensing (320) a temperature in proximity to a thermal module comprising at least one of a fuel tank, an electronic computing module, and a housing; and generating (330) an air stream based on the detected first threshold (310) and the sensed temperature (320). The device (200) and method (300) can automatically and dynamically manage, for example, temperature, oxygen and/or moisture of an energy storage module, to maintain the energy storage module within desired specifications and tolerances. This can help to prolong the useful life of the energy storage module and its components and help to maintain a maximum recharging capacity. |
US08318379B2 |
Membrane-electrode assembly for mixed reactant fuel cell and mixed reactant fuel cell system including same
A membrane-electrode assembly for a mixed reactant fuel cell and a mixed reactant fuel cell system including the same. In one embodiment of the present invention, a membrane-electrode assembly for a mixed reactant fuel cell includes an anode catalyst layer, a cathode catalyst layer, a polymer electrolyte membrane disposed between the anode catalyst layer and the cathode catalyst layer, an electrode substrate disposed on at least one of the anode catalyst layer or the cathode catalyst layer, and an oxidant supply path penetrating the polymer electrolyte membrane, the anode catalyst layer, the cathode catalyst layer, and the electrode substrate and adapted to supply an oxidant. |
US08318378B2 |
Fuel cell and fuel cell fastening device
A fuel cell (10) includes a fuel cell stack (50) in which a plurality of fuel cell units are stacked on one another, a pair of end plates (61, 61b, 63, 63b) respectively contact both ends of the fuel cell stack in a direction (Ds) in which the plurality of fuel cell units are stacked, and a side member (62, 62b, 62g) that extends in the stacking direction and is disposed between the end plates. The fuel cell further includes a connecting bolt portion, having a bolt shank (644, 624g) that penetrates one of the end plates substantially along the stacking direction. The connecting bolt portion connects the one of the end plates and the side member. The fuel cell further includes a cushion joint (66, 66a, 66b, 66c, 66d, 66e, 66f) disposed between the side member and one of the end plates, and through which the bolt shank passes. |
US08318374B2 |
Fuel cell comprising oxygen electrode with surface nanostructure
An oxygen electrode used in the fuel cell and includes a plurality of carbon particles, a carbon thin-film, and surface nanostructure. The carbon particles are bonded to one another with the carbon thin-film, and the surface nanostructure is formed on the surface of the carbon thin-film. The surface nanostructure comprises catalyst nanoparticles made of platinum (Pt) and carbon nanoparticles. According to this combination of these elements, the catalyst nanoparticles are confined within three-dimensional structure to be formed by the carbon nanoparticles and are immobilized without losing space which allows any reactant to be accessed to the surface of the catalyst nanoparticles. |
US08318372B2 |
Fuel cell stack and vehicle equipped with fuel cell system
A fuel cell stack in accordance with the invention has a cell laminate obtained by stacking multiple plates with at least one of functions of a power generation assembly and a separator, and a pair of end plates located outside and on both ends of the cell laminate in a stacking direction. The fuel cell stack further includes a displacement preventing member extended along the stacking direction of the cell laminate and fastened to the pair of end plates, and a deformable intermediate material located between the cell laminate and the displacement preventing member over an area of two or more plates among the multiple plates. At least either one of the two or more plates and the displacement preventing member is designed to have a concavo-convex shape formed at least partially on a face in contact with the intermediate material. Such a simple structure of the fuel cell stack effectively enhances the resistance against an inertial force acting in an in-plane direction that is perpendicular to the stacking direction. |
US08318367B2 |
Electrochemical energy generating apparatus and operating method thereof, and electrochemical device
An electrochemical energy generation device includes an electrochemical device such as a fuel cell having an electrolyte film arranged between an anode and a cathode and a reference electrode maintained at an oxidation-reduction potential between an metal and a metal ion and arranged in contact with the electrolyte film. The electrochemical energy generation device is operated by measuring a potential of the anode and the cathode based on the reference electrode, deciding the operation condition such as a fuel supply amount to the electrochemical device according to the result of the potential measurement of the anode and the cathode, and selling the operation condition such as the fuel supply amount according to the decision, by an operation condition setting unit. An operation method of the device and an electrochemical device constituting the device are also provided. |
US08318365B2 |
Fuel cell system with bypass path and operation method for controlling bypass path of fuel cell system
A fuel cell system of the present invention comprises a fuel cell (1) configured to generate electric power using a fuel gas, a fuel gas generator (2) configured to generate a fuel gas containing hydrogen using a raw material, a combustion burner (2a) configured to heat the fuel gas generator, a combustion fan (2b) configured to supply air to a combustion burner (2a), and a controller (101). The raw material is filled inside the fuel cell (1) before the fuel gas is supplied to the fuel cell. The controller (101) controls on-off valves (8, 9) to cause the fuel gas to branch to flow to a second path (R2) and to a fourth path (R4) when the fuel gas generated in the fuel gas generator (2) starts to be supplied to the fuel cell (1). |
US08318353B2 |
Method for making electrode active materials
The present invention is directed to a method for making electrode active materials represented by the general formula: Aa(VO)bXO4, wherein: (a) A is an alkali metal or mixture of alkali metals, and 0 |
US08318342B2 |
All solid-state polymer battery
An all solid-state polymer battery uses: 1) a lithium based negative electrode active material including crystal grains and crystal grain boundaries, wherein at least part of the crystal grain boundaries are exposed on a surface of the lithium-based negative electrode active material, and the area of the exposed surface of the crystal grain boundaries is 0.02 to 0.5 cm2 per square centimeter of surface; 2) a dry polymer electrolyte including a specific ethylene glycol ether, a polymer containing electron-donating oxygen atoms in the skeleton, and a lithium salt; or 3) an amorphous lithium nitride layer formed between the negative electrode and the polymer electrolyte. This reduces the resistance at the interface between the negative electrode and the polymer electrolyte, thereby providing an all solid-state polymer battery with high capacity and excellent cycle characteristics. This also suppresses an increase in internal resistance during storage, thereby providing an all solid-state polymer battery with excellent high-rate discharge characteristics after storage. |
US08318337B2 |
Battery including electrode lead having high resistant portion
A battery includes an electrode assembly including a first electrode and a second electrode, a non-aqueous electrolyte, a battery case, a first lead connecting the first electrode with a bottom of the battery case, a seal member sealing an opening of the battery case, and a second lead connecting the second electrode with the seal member. At least one of the first lead and the second lead has a high resistant portion that has a higher resistance than the other portions per unit length. The high resistant portion is disposed at a position of the first lead closer to the first electrode than the portion connected to the bottom of the battery case or at a position of the second lead closer to the second electrode than the portion connected to the seal member. The high resistant portion is in contact with the battery case or the seal member. |
US08318336B2 |
Rechargeable battery
A rechargeable battery includes an electrode assembly having positive and negative electrodes and a separator interposed between the positive and negative electrodes. Each of the positive and negative electrodes has an active material coated part and an active material uncoated part. A case receives the electrode assembly, the case being provided with an opening through which the electrode assembly is inserted therein. A cap plate is coupled to the opening. An electrode terminal is coupled to a through-hole formed on the cap plate and protrudes out of the case. A current collector has a flange part with a cross-sectional area greater than the through-hole and a contacting part which connects the current collector to the active material uncoated part. |
US08318332B2 |
Magnetic recording medium, method for fabricating the same, and magnetic storage device
A discrete track medium and a patterned medium that are excellent in both magnetic recording properties and corrosion resistance are realized. The medium has a magnetic recording layer, which includes a magnetic region formed in a projection portion of a projection/recess pattern over a substrate and a filler region embedded in a recess portion of the projection/recess pattern, and an organic compound, which exhibits corrosion inhibition action for cobalt or cobalt alloys, between the magnetic region and the filler region. |
US08318329B2 |
Radiation-selective absorber coating, absorber tube and process for production thereof
The radiation-selective absorber coating (20) has two barrier layers (24a, 24b), an IR-reflecting layer (21) arranged thereon, an absorption layer (22) arranged above the IR-reflecting (21) and an antireflection layer (23) over the absorption layer (22). The absorber tube (13) is a steel tube (1) with the radiation-selective absorber coating (20) applied to the outside thereof. In the process of coating the absorber tube (13) a first oxide barrier layer (24a) is applied to a steel tube by thermal oxidation; a second barrier layer (24b) is then applied by physical gas phase deposition of silicon with supply of oxygen; the IR-reflecting layer (21) is then applied by gas phase deposition of gold, silver, platinum or copper; the absorption layer (22) is then applied by deposition of aluminum and molybdenum; and a final antireflection layer (23) is applied by deposition of silicon with supply of oxygen. |
US08318327B2 |
Low contamination components for semiconductor processing apparatus and methods for making components
Components of semiconductor processing apparatus are formed at least partially of erosion, corrosion and/or corrosion-erosion resistant ceramic materials. Exemplary ceramic materials can include at least one oxide, nitride, boride, carbide and/or fluoride of hafnium, strontium, lanthanum oxide and/or dysprosium. The ceramic materials can be applied as coatings over substrates to form composite components, or formed into monolithic bodies. The coatings ca protect substrates from physical and/or chemical attack. The ceramic materials can be used to form plasma exposed components of semiconductor processing apparatus to provide extended service lives. |
US08318325B2 |
Anthracene derivatives and organic electronic device using same
The present invention provides a novel anthracene derivatives and an organic electronic device using the same. The organic electronic device according to the present invention shows excellent properties in terms of efficiency, a driving voltage, and a life span. |
US08318324B2 |
Organic electroluminescence device and anthracene derivative
An anthracene derivative having a specific asymmetric structure is provided. The asymmetric anthracenes are useful in an organic electroluminescence device and exhibit efficient light emission and a long performance lifetime. |
US08318323B2 |
Polycyclic compounds and organic electroluminescence device employing the same
Provided are a polycyclic compound of a compound having such a structure that two benzene rings bond to a central benzene ring each other to form a fused ring and another fused ring bonds to a terminal thereof, and an organic electroluminescence device including one or more organic thin film layers containing a light emitting layer between a cathode and an anode, in which at least one of the organic thin film layers includes the polycyclic compound of the present invention. The organic electroluminescence device has high luminous efficiency, no defect in pixels, and long lifetime. In addition, provided is a polycyclic compound realizing the organic electroluminescence device. |
US08318312B2 |
Heat treatable coated article with zinc-doped zirconium based layer(s) in coating
In certain example embodiments, a coated article includes a Zn-doped zirconium based layer before heat treatment (HT). The coated article is heat treated sufficiently to cause the Zn-doped zirconium based layer to transform into a Zn-doped zirconium oxide based layer that is scratch resistant and/or chemically durable. The doping of the layer with Zn has been found to improve scratch resistance and/or corrosion resistance. |
US08318309B2 |
Benzylated aminopropylated alkylenediamines and uses thereof
The present invention provides epoxy curing agent compositions comprising benzylated aminopropylated alkylenediamine compounds. Amine-epoxy compositions and articles produced from these amine-epoxy compositions are also disclosed. |
US08318308B2 |
Single-walled carbon nanotube and aligned single-walled carbon nanotube bulk structure, and their production process, production apparatus and application use
This invention provides an aligned single-layer carbon nanotube bulk structure, which comprises an assembly of a plurality of aligned single-layer carbon nanotube and has a height of not less than 10 μm, and an aligned single-layer carbon nanotube bulk structure which comprises an assembly of a plurality of aligned single-layer carbon nanotubes and has been patterned in a predetermined form. This structure is produced by chemical vapor deposition (CVD) of carbon nanotubes in the presence of a metal catalyst in a reaction atmosphere with an oxidizing agent, preferably water, added thereto. An aligned single-layer carbon nanotube bulk structure, which has realized high purify and significantly large scaled length or height, its production process and apparatus, and its applied products are provided. |
US08318307B2 |
Electrochemical depositions applied to nanotechnology composites
A method of improving the material properties of a composite by electrodepositing various polymers, organic compounds or inorganic compounds onto each individual carbon (graphite) fiber strand, whether individual fiber or as a fabric to form an homogeneous chemically-bonded composite as opposed to the formation of a heterogeneous, non-chemically bonded composite. Thus, electrodeposition forms a unique discrete interface at the molecular layer (nanolayer) between the reinforcement (fiber) and the matrix (resin) over as opposed to any previous resin infusion process. |
US08318305B2 |
Resin composition
A resin composition comprising a fiber component and a resin component, whereinthe fiber component is (A) a surface-treated fiber (component A) which comprises 100 parts by weight of a fiber comprising a polyalkylene terephthalate and/or a polyalkylene naphthalene dicarboxylate (component Af) and 0.1 to 10 parts by weight of a sizing agent having a glass transition point of −80° C. or higher and lower than 70° C. and adhered to the surface of the fiber (component Ac); andthe resin component comprises (B) an ethylene-based copolymer containing a glycidyl group (component B), (C) a modified polyolefin resin modified with an unsaturated carboxylic acid and/or an unsaturated carboxylic acid derivative (component C), and (D) a polyolefin resin having a melt flow rate of 40 to 200 g/10 min (component D), except for the components C and D, the content of the component D being 30 to 850 parts by weight based on 100 parts by weight of the component A, and the total content of the components B and C being 5 to 630 parts by weight based on 100 parts by weight of the component A,and a molded article thereof. |
US08318301B2 |
Antireflection film, polarizing plate and image display device
Provided is an antireflection film including, in the following order: a transparent support; at least one antiglare layer or diffusive layer containing a transparent resin and light-transmissive resin particles; and a low-refractivity layer having a refractive index lower than that of any of the transparent support and the antiglare layer or diffusive layer, wherein the transparent resin is formed by curing a mixture containing (A) a polyfunctional (meth)acrylate having at least two (meth)acryloyl groups, and (B) a modified polyfunctional (meth)acrylate modified through addition of any of ethylene oxide, propylene oxide or caprolactone, and the light-transmissive resin particles contain (C) high-crosslinking light-transmissive particles which are so high-crosslinking as to have a residual monomer content of at most 2.0% and which have a compression strength of from 39 to 98 N/mm2. |
US08318296B2 |
Composite article
A composite includes a first preform and a second preform spaced from and in overlying relationship to the first preform. The second preform defines at least one first opening extending therethrough along an axis transverse to the first preform. A first surface layer is disposed adjacent to the second preform and on an opposite side of the second preform from the first preform. A polymeric composition including the reaction product of an isocyanate component and an isocyanate-reactive component is disposed between the first preform and the second preform. The polymeric composition adheres the first surface layer to the second preform through the at least one first opening. The surface layer is adhered to the second preform during molding of the composite article and in the absence of additional adhesive, thereby reducing production time and cost of the composite article. |
US08318294B2 |
Optical film, process for producing the same, and polarization plate utilizing the film
An optical film that even in the event of aging (storage) of optical film formed into thin film and large width in the form of lengthy roll, is free from the danger of sticking failure and protrusion failure attributed to uplift of the film due to local film friction; a process for producing such an optical film; and a polarization plate utilizing the optical film. The optical film is one of large width containing a plasticizer, produced by a solution casting process, wherein the value (X) calculated by formula (1) from the value (A) measured by TOF-SIMS with respect to the plasticizer lying in the surface-side central area of the optical film and the value (B) measured by TOF-SIMS with respect to the amount of plasticizer lying in the backside central area of the optical film is different from the value (X′) calculated by formula (2) from the value (A′) measured by TOF-SIMS with respect to the amount of plasticizer lying in the surface-side two lateral edge portions of the optical film and the value (B′) measured by TOF-SIMS with respect to the amount of plasticizer lying in the backside two lateral edge portions of the optical film, and wherein the value (X) is smaller than the value (X′). |
US08318293B2 |
Coated cutting tool insert
The present invention relates to a CVD-coated cutting tool insert with a TiCxNy-layer with a low tensile stress level of from about 50 to about 390 MPa and an α-Al2O3-layer with a high surface smoothness with a mean Ra<0.12 μm as measured by AFM-technique. This is obtained by subjecting the coating to an intensive wet blasting operation. |
US08318289B2 |
Coated polymeric substrates having improved surface smoothness suitable for use in flexible electronic and opto-electronic devices
A composite film comprising a heat-stabilised, heat-set, oriented poly(ethylene naphthalate) substrate, and a coating layer having a surface; wherein said substrate exhibits one or more of: (i) a shrinkage at 30 mins at 230° C. of less than 1%; and/or (ii) a residual dimensional change ΔLr measured at 25° C. before and after heating the substrate from 8° C. to 200° C. and then cooling to 8° C., of less than 0.75% of the original dimension; and/or (iii) a coefficient of linear thermal expansion (CLTE) within the temperature range from −40° C. to +100° C. of less than 40×10−6/° C.; and wherein the surface of said coating layer exhibits an Ra value of less than 0.6 nm, and/or an Rq value of less than 0.8 nm, the thickness of the substrate is between 50 and 250 μm and wherein the number of surface peaks in the range 300 to 600 nm per 5 cm2 area (N(300-600)) of the film is less than 50. |
US08318286B2 |
Gas catalysts comprising porous wall honeycombs
Embodiments of the invention pertain to a catalyst, which may be used in a catalytic converter for treating a gas stream containing pollutants. In an embodiment, the catalyst comprises a substrate having a plurality of axially enclosed channels defined by the porous wall elements extending between an inlet end and an outlet end. Washcoat particles are disposed substantially within the pores of the walls, and the surfaces of the wall elements have a porous, rough texture after coating with the washcoat and substantially no fillets formed on the channels. |
US08318285B1 |
Article for absorbing fluids
An article for absorbing fluids that includes a backing sheet and an absorption sheet, wherein the absorption sheet is made of a material that is capable of absorbing any oil based liquid, and wherein the backing sheet is at least partly affixed to the absorption sheet; at least one first fastener means, wherein the first fastener means includes an attachment means on the bottom side and a mating attachment means on the top side, and wherein the bottom side of the first fastener means is at least partly affixed to a top side of the absorption sheet; and one or more malleable strips positioned along at least a portion of a length of the article. |
US08318283B2 |
Blow mold and backfill manufacturing process
Disclosed embodiments may include methods for forming a foam product comprising forming a skin and inserting a bracket at least partially into the skin. Another embodiment method for manufacturing a foam product may comprise sealing a tube of material in a cavity of a mold, blowing air into the tube of material to form a skin comprising an interior surrounded by a wall, cutting an incision in the skin wall, inserting a bracket through the incision and into the skin interior, filling the skin interior with foam, and curing the foam. Disclosed embodiments may further include foam product comprising a skin with an interior surrounded by a wall, a bracket within the skin interior, a foam substantially filling the skin interior and securing the bracket in place, a recessed region configured to mate with a mounting assembly on a chair, and an incision in the skin wall, the incision positioned outside of the recessed region. |
US08318282B2 |
Microstructured antimicrobial film
A microstructured antimicrobial film, an antimicrobial film assembly, a method of protecting a surface from microbial contamination, and a method of making a microstructured antimicrobial film. The microstructured antimicrobial film can include a substrate having a first side that includes a first major surface, a plurality of microstructured wells defined in the first side of the substrate, and an antimicrobial material positioned within at least some of the plurality of wells. Each of the plurality of wells can be at least partially defined by a base that is spaced a distance from the first major surface of the substrate. The antimicrobial material can be positioned, such that an upper surface of the antimicrobial material is spaced a distance from the first major surface of the substrate. The antimicrobial film assembly can include a roll or a stack of microstructured antimicrobial films. |
US08318281B2 |
Laminated paper article and paper web
An absorbent laminated paper article is a rectangular sheet having first parallel edges in a first direction, second parallel edges in a second perpendicular direction and an article area delimited by the edges. The article includes at least two plies adhesively bonded in a bonding pattern between the plies. The bonding pattern includes bonding elements arranged along a first set of bonding lines extending from one of the first parallel edges to the other of first parallel edges in a first direction at a first angle to the first direction and along a second set of bonding lines extending from the one of first parallel edges to the other of first parallel edges in a second direction at a second angle to the first direction, the first set of bonding lines intersecting with the second set and forming an intermeshing network of bonding lines. |
US08318272B1 |
Decorative tubular art form and method of assembly thereof
A system and method by which new or recycled paper is rolled and assembled to form artwork is herein disclosed. The art form comprises a plurality of pre-rolled or flat pieces of paper that are rolled and formed into tubes. These tubes are then taped to hold them together, and if desired, folded inwardly at end portions for aesthetic purposes. Next, the tubes are arranged in a two-layer matrix forming an initial panel and secured using plastic wire ties. The panels are then layered and joined using the wire ties to form various finished designs. When completed, the art assembly comprises various abstract pieces of art being flat, non-flat, three-dimensional, or the like, that can be hung on a wall, stood upon a floor, or suspended from a ceiling. It is envisioned that the art form may be provided using recycled paper from catalogues and magazines to provide lively colors and brightly colored pattern that is also ecologically friendly. It is envisioned that the art form is to be sold in a kit format with the paper in a flat form to be rolled by the final user. The kit would be packaged with a suitable number of wire ties, common adhesive tape, and instructions for producing one (1) or more pieces of artwork. |
US08318270B2 |
Liquid crystal display panel and method of manufacturing the liquid crystal display panel
A liquid crystal display (“LCD”) panel includes a first substrate including a pixel electrode defining pixel areas, a first alignment layer disposed on the pixel electrode and a first reactive mesogen layer disposed on the first alignment layer, a second substrate including a common electrode layer disposed on an entire portion of the second substrate facing the first substrate, a second alignment layer disposed on the common electrode layer and a second reactive mesogen layer disposed on the second alignment layer, and a liquid crystal layer disposed between the first and second substrates and including a first liquid crystal compound represented by Chemical Formula 1, a second liquid crystal compound represented by Chemical Formula 2 and a third liquid crystal compound represented by Chemical Formula 3: |
US08318269B2 |
Induction for thermochemical processes, and associated systems and methods
Induction for thermochemical processes, and associated systems and methods are disclosed. A method in accordance with a particular embodiment includes placing first and second substrates in a reactor, with each substrate having a surface facing toward the other. Method can further include directing a precursor gas into the reactor and activating an induction coil proximate to the facing surfaces of the substrates to dissociate the precursor gas. A constituent of the precursor gas is deposited on both the first and second surfaces, and heat radiated from each surface and/or a constituent deposited on the surface is received at the other surface and/or the constituent deposited on the other surface. |
US08318268B2 |
AA stacked graphene-diamond hybrid material by high temperature treatment of diamond and the fabrication method thereof
There is provided a fabrication method for an AA stacked graphene-diamond hybrid material by converting, through a high temperature treatment on diamond, a diamond surface into graphene. According to the present invention, if various types of diamond are maintained at a certain temperature having a stable graphene phase (approximately greater than 1200° C.) in a hydrogen gas atmosphere, two diamond {111} lattice planes are converted into one graphene plate (2:1 conversion), whereby the diamond surface is converted into graphene in a certain thickness, thus to fabricate the AA stacked graphene-diamond hybrid material. |
US08318267B2 |
Method and apparatus for forming silicon oxide film
An object to be processed which has silicon on its surface is loaded in a processing chamber. A plasma of a processing gas containing oxygen gas and nitrogen gas is generated in the processing chamber. The silicon on the surface of the object to be processed is oxidized by the plasma, thereby forming a silicon oxide film. |
US08318265B2 |
Plasma mediated processing of non-conductive substrates
Methods for improving coating or etching uniformity of non-conductive substrates in plasma-mediated processes generally include applying an electrically conductive coating to the non-conductive substrate prior to plasma processing. The electrically conductive coating is disposed in electrical communication with a metallic electrode of a plasma reactor. By disposing a conductive layer on the non-conductive substrate, a uniform electric potential is created during plasma processing can be built up on the non-conductive, which is equivalent to that of the metallic electrode upon which it is disposed during plasma processing. |
US08318264B2 |
Process for functionalizing a glass reinforcement for composite material
Process for surface functionalization of a glass reinforcement, characterized in that the said reinforcements are chemically modified by means of surface treatment by the action of a homogeneous plasma at atmospheric or sub-atmospheric pressure in a controlled, oxidizing or nitriding gas atmosphere, and in that the said surface portion is contacted with an aqueous impregnating solution of an organic or inorganic matrix, or directly with the matrix. |
US08318263B2 |
Method for coating an object with a graft polymer layer
Described herein is a method for coating an object with a polymer layer. The method includes contacting the object with a first solution comprising a non-polymeric grafting initiator comprising at least one photoinitiator group capable of generating a free radical active species upon absorption of electromagnetic energy, wherein the photoinitiator group is selected from the group consisting of an initiator that is insoluble in polar solvent; and a negatively charged initiator; irradiating the first solution and the object, resulting in the grafting initiator binding to the object; removing the first solution; contacting the object with a second solution comprising a polymerizable monomer having at least one free-radical polymerizable group; and irradiating the second solution and the object, wherein the non-polymeric grafting initiator acts as a photoinitiator for a free-radical polymerization reaction. |
US08318262B2 |
Use of spherical metal particles as laser-marking or laser-weldability agents, and laser-markable and/or laser-weldable plastic
The invention relates to the use of spherical metal particles, which are free of antimony and/or antimony-containing compounds, as a laser marking agent or laser weldability agent in a plastic, wherein the particle size distribution of the spherical metal particles, as determined by means of laser granulometry, in the form of the volume-averaged cumulative undersize particle size distribution, has a D99 value of <110 μm, a D90 value of <75 μm, and a D50<45 μm.The invention further relates to a laser-markable and/or laser-weldable plastic which a laser marking agent consisting of spherical metal particles, which are free of antimony and/or antimony-containing compounds, wherein the particle size distribution of the spherical metal particles, as determined by means of laser granulometry, in the form of the volume-averaged cumulative undersize particle size distribution, has a D99 value of <110 μm, a D90 value of <75 μm, and a D50<45 μm. |
US08318261B2 |
Thermally sprayed Al2O3 coatings having a high content of corundum without any property-reducing additives, and method for the production thereof
The disclosure provides a method of producing thermally sprayed Al2O3 coatings having a high content of corundum without any property-reducing additives. The coatings may be utilized particularly in the field of electrical insulation, as a dielectric, and as protection from wear. The thermally sprayed Al2O3 coatings have a porosity of no more than 19%, and a high content of α-Al2O3 (content of corundum) of at least 72% by volume. The coatings have a specific electrical resistance of >1·1012 Ohms·cm, and a purity of >97%. The production of said coatings is carried out utilizing aqueous or alcoholic suspensions made from substantially pure α-Al2O3, having a grain size of >100 nm by thermal spraying. |
US08318257B2 |
Dispersions of higher crystallinity olefins
Dispersions and methods for forming dispersions that include a higher crystallinity polyolefin and at least one dispersing agent are disclosed. Various applications for use of the dispersions are also disclosed. |
US08318252B2 |
Antimony precursors for GST films in ALD/CVD processes
The present invention is a process of making a germanium-antimony-tellurium alloy film using a process selected from the group consisting of atomic layer deposition and chemical vapor deposition, wherein a silylantimony precursor is used as a source of antimony for the alloy film. Novel silylantimony compounds are also disclosed. |
US08318251B2 |
Method for coating honeycomb seal using a slurry containing aluminum
A method and composition are provided for coating honeycomb seals and, more specifically, to a method and slurry for applying an aluminide coating onto honeycomb seals. The method includes preparing a slurry of a powder containing a metallic aluminum alloy having a melting temperature higher than aluminum, an activator capable of forming a reactive halide vapor with the metallic aluminum, and a binder containing an organic polymer. The slurry is applied to surfaces of the honeycomb seal, which is then heated to remove or burn off the binder, vaporize and react the activator with the metallic aluminum to form the halide vapor, react the halide vapor at the substrate surfaces to deposit aluminum on the surfaces of the seal, and diffuse the deposited aluminum into the surfaces to form a diffusion aluminide coating. |
US08318250B2 |
Anchored nanostructure materials and method of fabrication
Anchored nanostructure materials and methods for their fabrication are described. The anchored nanostructure materials may utilize nano-catalysts that include powder-based or solid-based support materials. The support material may comprise metal, such as NiAl, ceramic, a cermet, or silicon or other metalloid. Typically, nanoparticles are disposed adjacent a surface of the support material. Nanostructures may be formed as anchored to nanoparticles that are adjacent the surface of the support material by heating the nano-catalysts and then exposing the nano-catalysts to an organic vapor. The nanostructures are typically single wall or multi-wall carbon nanotubes. |
US08318247B2 |
Coating treatment method, coating treatment apparatus, and computer-readable storage medium
The present invention includes: a first step of discharging a coating solution from a nozzle to a center portion of the substrate to apply the coating solution on a surface of the substrate while rotating the substrate; a second step of decelerating, after the first step, the rotation of the substrate and continuously rotating the substrate; and a third step of accelerating, after the second step, the rotation of the substrate to dry the coating solution on the substrate, wherein: the substrate is rotated at a fixed speed of a first speed immediately before the first step; and in the first step, the rotation of the substrate which is at the first speed before start of the first step is gradually accelerated after the start of the first step so as to make the speed continuously change, and the acceleration of the rotation of the substrate is gradually decreased so as to make the speed of the rotation of the substrate converge in a second speed higher than the first speed at end of the first step. |
US08318246B2 |
Process for preparing compacted pigment granules, process for preparing encapsulated pigment granules, and process for dyeing landscaping and/or construction materials
A process for preparing compacted pigment granules, comprising the steps of (1) loading iron oxide powder into a rotating mixer; (2) spraying, while the mixer is rotating, liquid binder solution onto the cascading pigment powder, whereby the cascading pigment powder is compacted into dense granules of approximately 0.3-1.2 mm diameter and having a moisture content of approximately 10-14%; and (3) directing, while the mixer is rotating, heated air at a temperature of 200-600° C. onto the compacted pigment granules, so that the compacted pigment granules are dried at a temperature of approximately 50-100° C., and continuing this process for approximately 2-3 hours until the moisture content of the compacted pigment granules is reduced to approximately 2% or less, whereupon the compacted pigment granules are removed from the mixer, and a process for preparing encapsulated pigment granules. |
US08318244B2 |
Use of glassy silicone-based hard coating as release coatings for printable electronics
A method for fabricating electronic devices includes the steps of 1) printing a multi-layer electronic device on a silicone-based hard coating on a substrate, and 2) removing the device from the substrate. The silicone-based hard coating is an abrasion resistant coating with hardness ranging from 1 to 10 gigaPascals. |
US08318243B2 |
Method for manufacturing optical information recording medium
Disclosed is a method for manufacturing an optical information recording medium. The method includes laminating plural layers successively on a substrate having a through-hole at its center; and fitting center caps each having a predetermined radius in the through-hole to form at least two of the plural layers by a spin coat method. A radius of a first center cap used for forming an upper layer of the at least two layers is larger than a radius of a second center cap used for forming a lower layer thereof. |
US08318242B2 |
Systems and methods for protecting a sensitive device from corrosion
A method in one embodiment includes applying an organic coating to a magnetic head for reducing exposure of the head to oxidation promoting materials; and storing the magnetic head. A method in another embodiment includes applying an organic coating to a magnetic head for reducing exposure of the head to oxidation promoting materials, the organic coating being applied to the magnetic head after the head is installed in the magnetic storage system. Another method includes fabricating a tape having an applicator portion for applying an organic coating to a magnetic head for reducing exposure of the head to oxidation promoting materials; applying the organic coating to the applicator portion of the tape; and applying a lubricant to a data portion of the tape. A method in another embodiment includes fabricating a tape having a data portion, and a cleaning portion for removing an organic coating from a magnetic head. |
US08318235B2 |
Method for applying drug coating to a medical device in surgeon room
Medical devices, and in particular implantable medical devices such as stents and stent delivery systems including catheters, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism or to treat a particular condition. A dip coating process is utilized to minimize waste and to customize coating thickness and drug loading directly at the clinical site just prior to therapeutic use on a patient. An aqueous latex polymeric emulsion is utilized to coat any medical device to a desired thickness by allowing for successive dipping and drying cycles at the clinical site. In addition, aqueous latex polymeric emulsions pose less of a chance of the bridging phenomenon associated with organic solvent based polymers. |
US08318234B2 |
Mixed aqueous solution of L-lysine and L-threonine and method of preparing same
The present invention provides a mixed aqueous solution of L-lysine and L-threonine, which is industrially useful as an animal feed ingredient. The solution is stable, concentrated, and has good handleability. Therefore, a mixed aqueous solution of L-lysine and L-threonine is provided which contains L-lysine, L-threonine, and water. The solution has a viscosity of 3300 cp or less at 20° C., a pH of 10-13, and a total concentration of L-lysine and L-threonine in the mixed aqueous solution of 70 g/100 g of water or more. |
US08318233B2 |
Emulsions useful in beverages
It has now been found that emulsions having a discrete phase volume fraction of 60% to 67% with excellent stability may be prepared using at least one low molecular weight surfactant. Such emulsions have high oil loading and a small mean particle size of less than 0.2 microns. Further, such emulsions may be used in beverages without weighting agents. |
US08318227B2 |
Cooking accessory and method
A method and apparatus are disclosed for removing fat floating on hot soup. A thermally conducting plate 14 having a flat underside is cooled to a temperature below that at which the flat solidifies and lowered onto the floating fat to cause the fat to congeal and adhere to its underside. The plate 14 is then raised to remove the adhering fat from the soup, and the fat adhering to the underside is scraped off by dragging the underside across a straight edge 22. |
US08318225B2 |
Composition for enhancing physical performance
This invention relates to a composition that contains quercetin, vitamin B1, vitamin B2, vitamin B3, vitamin B6, vitamin B12, vitamin C, caffeine, epigallocatechin gallate, epicatechin, epicatechin gallate, and epigallocatechin. |
US08318222B2 |
Topical skin care formulation
Disclosed is a multi-beneficial topical skin care composition, and methods for its use, that can hydrate skin, increase the firmness of skin, reduce the appearance of fine lines or wrinkles on skin, and reduce the appearance of age spots on skin. The composition can include a combination of skin active ingredients comprising euterpe oleracea fruit extract, punica granatum sterols, caprooyl tetrapeptide-3, tocopherol or tocopherol acetate, and niacinamide, a combination of skin moisturizing agents comprising glycerin and butyrospermum parkii, a photo stable combination of sunscreen agents providing the composition with a sun protection factor (SPF) of at least about 15, and a dermatologically acceptable vehicle which imparts a non-greasy feel when applied to skin. |
US08318220B2 |
Bioactive compositions from Theacea plants and processes for their production and use
The present invention relates to isolated bioactive compositions containing bioactive fractions derived from Theacea plants. The present invention also relates to bioactive topical formulations containing the bioactive compositions. The present invention further relates to methods of using the bioactive compositions of the present invention, including, for example, methods for inhibiting inflammatory activity in skin tissue of a mammal, for protecting skin tissue of a mammal from ultraviolet light-induced damage, and for normalizing skin disorders in skin tissue of a mammal. The present invention also relates to methods for isolating bioactive fractions derived from cell juice or a cell walls component a Theacea plant. |
US08318218B2 |
Composition comprising 1,3/1, 6 beta glucan for reducing weight
Beta-1,3/1,6-glucan for use as a slimming aid or in weight loss or for the treatment of obesity. |
US08318216B2 |
Ayurvedic formulation advocated for the prevention and management of coronary heart disease
A novel herbal formulation for the prevention and management of various CHD risk factors including vascular inflammatory process responsible for cardiovascular events comprising a hydro-alcoholic extraction of Commiphora mukul, Terminalia arjuna, Inula recemosa and Hippophae rhamonoides with or without known additives. |
US08318214B2 |
Method for treating onychoschizia
Method for the treatment of onychoschizia in a patient having onychoschizia. The method is performed by administering to the patient a topical composition including (a) at least one herb extract from the genus Equisetum, and (b) at least one water-soluble film forming agent which is a derivative of chitosan. |
US08318211B2 |
Therapeutic polymeric nanoparticles comprising vinca alkaloids and methods of making and using same
The present disclosure generally relates to therapeutic nanoparticles. Exemplary nanoparticles disclosed herein may include about 1 to about 20 weight percent of a vinca alkaloid; and about 50 to about 99 weight percent biocompatible polymer. |
US08318206B2 |
Particles
The present invention provides a particle aggregate comprising particles linked to other particles via linkers that are capable of being cleaved by an enzyme. The particles may be linked directly to other particles by the linkers or may be linked indirectly by means of a binding moiety. The invention also provides a particle coupled to a binding moiety via a linker that can be cleaved by an enzyme. The present invention may be used in diagnosing a disease or condition associated with the enzyme, or may be used to treat such a disease or condition whereby the drug is retained in the particle aggregate until the linkers are cleaved by the enzyme. |
US08318204B2 |
pH sensitive block copolymer and polymeric micelle using the same
Disclosed is a pH-sensitive block copolymer obtained by copolymerization of: (a) a polyethylene glycol compound (A); and (b) at least one poly(amino acid) compound selected from the group consisting of a poly(β-amino ester) and poly(amido amine) or a copolymer thereof (B). A method for preparing the same block copolymer, and a polymer micelle type drug composition comprising the pH-sensitive block copolymer and a physiologically active substance that can be encapsulated with the block copolymer are also disclosed. The pH-sensitive block copolymer is obtained by polymerization of a hydrophilic polyethylene glycol compound with a pH-sensitive biodegradable poly(amino acid) compound. Therefore, the pH-sensitive block copolymer can form a micelle structure due to its amphiphilicity and ionization characteristics depending on pH variations, and thus can be used as drug carrier for target-directed drug delivery depending on pH variations in the body. |
US08318199B2 |
Liposome for liver-specific delivery and release of therapeutic nucleic acids or drugs
Disclosed herein is a composite of a nanoscale particle size. The composite is able to specifically deliver therapeutic agents such as therapeutic nucleic acids or drugs to the liver and selectively release them into hepatic cells to manifest potent therapeutic effects of the therapeutic agents. The composite may be comprised of an apolipoprotein A-1 and a liposome-forming material. A composition containing the composite and a pharmaceutically acceptable carrier is disclosed. |
US08318195B2 |
Controlling resorption of bioresorbable medical implant material by application of microwave, ultrasound or radiofrequencies
The resorption of a medical implant can be controlled with the use of particles embedded in a resorbable bulk material forming the implant or portion thereof. The implant can be removed from a body of a mammal by natural biological mechanisms after use. The resorption of the implant can involve swelling and/or hydrolyzing of the particles within the implant upon contact with a body fluid such that porosity and flow of fluid within the bulk material of the implant is increased. Resorption of the implant may also involve the use of particles with magnetic properties embedded within the implant such that an applied magnetic field causes the particles to vibrate within the bulk material thereby increasing the porosity and thus the flow of fluid, hence facilitating resorption of the implant. The resorption rate of the implant can be controlled by modulating swelling, hydrolysis, or movement of the embedded particles. |
US08318194B2 |
Implants for administering substances and methods of producing mesoporous implants
A porous silicon implant impregnated with a beneficial substance, such as a micromineral required for healthy physiology, is implanted subcutaneously and is entirely corroded away over the following months/year to release the micromineral in a controlled manner. In a second embodiment the implant may have a large number of holes which contain beneficial substance and which are closed by bio-errordable doors of different thickness so as to stagger the release of the beneficial substance over time as the doors are breached. |
US08318190B2 |
Method of treating disorders using compositions comprising zotarolimus and paclitaxel
A system and compositions including zotarolimus and paclitaxel are disclosed, as well as methods of delivery, wherein the drugs have effects that complement each other. Medical devices are disclosed which include supporting structures that include at least one pharmaceutically acceptable carrier or excipient, which carrier or excipient can include one or more therapeutic agents or substances, with the carrier including at least one coating on the surface thereof, and the coating associated with the therapeutic substances, such as, for example, drugs. Supporting structures for the medical devices that are suitable for use in this invention include, but are not limited to, coronary stents, peripheral stents, catheters, arterio-venous grafts, by-pass grafts, and drug delivery balloons used in the vasculature. These compositions and systems can be used in combination with other drugs, including anti-proliferative agents, anti-platelet agents, anti-inflammatory agents, anti-thrombotic agents, cytotoxic drugs, agents that inhibit cytokine or chemokine binding, cell de-differentiation inhibitors, anti-lipaedemic agents, matrix metalloproteinase inhibitors, cytostatic drugs, or combinations of these and other drugs. |
US08318187B2 |
Long-wearing cosmetic compositions with improved shine
A cosmetic composition comprising (A) a first structured and adhesive film-forming fatty phase comprising (i) one or more lipidic components that are mutually compatible with one another when liquefied; (ii) at least one adhesive film-forming agent; and (iii) at least one lipophilic structuring agent in an amount effective to retain a second fatty phase entrapped in said cosmetic composition prior to application on mammalian keratinous tissue; and (B) a second fatty phase comprising at least one non-volatile lipidic component wherein said second fatty phase (B) is incompatible with said first structured and adhesive film-forming fatty phase (A) and said second fatty phase (B) is entrapped in said composition where upon application of said composition to mammalian keratinous tissue, said second fatty phase (B) readily separates from said composition to form a barrier layer over said first structured and adhesive film-forming fatty phase (A) and wherein said composition is substantially free of surfactants such that separation of said second fatty phase (B) from said composition is not prevented following application of said composition. |
US08318185B2 |
Recombinant malaria vaccine
The present invention refers to a recombinant malaria vaccine and a method for its manufacture. |
US08318182B2 |
Vault compositions for immunization against Chlamydia genital infection
Methods and compositions are provided herein for immunizing a subject against Chlamydial genital infection by administering to the subject an effective amount of a Chlamydial immunogenic peptide or an immunogenic fragment or variant thereof incorporated within a vault-like particle carrier. In some aspects, the vault-like-particles are administered to the nasal mucosa. The methods and compositions advantageously exhibit enhanced ability to induce cell-mediated immunity and/or antibody-based immunity at mucosal surfaces while reducing inflammation associated with Chlamydia infection. |
US08318174B2 |
Survivin-derived peptides and use thereof
MHC Class I-restricted peptides derived from the tumor associated antigen, survivin, which peptides are capable of binding to Class I HLA molecules at a high affinity, capable of eliciting INF-γ-producing cells in a PBL population of a cancer patient and capable of in situ detection of cytotoxic T cells in a tumor tissue, therapeutic and diagnostic composition comprising the peptide and uses thereof. |
US08318173B2 |
Chimeric vaccines
The invention provides chimeric proteins and nucleic acids encoding these which can be used to generate vaccines against selected antigens. In one aspect, a chimeric protein comprises an antigen sequence and a domain for trafficking the protein to an endosomal compartment, irrespective of whether the antigen is derived from a membrane or non-membrane protein. In one preferred aspect, the trafficking domain comprises a lumenal domain of a LAMP polypeptide. Alternatively, or additionally, the chimeric protein comprises a trafficking domain of an endocytic receptor (e.g., such as DEC-205 or gp200-MR6). The vaccines (DNA, RNA or protein) can be used to modulate or enhance an immune response against any kind of antigen. In one preferred aspect, the invention provides a method for treating a patient with cancer by providing a chimeric protein comprising a cancer-specific antigen or a nucleic acid encoding the protein to the patient. |
US08318171B2 |
Neurotoxic oligomers
This invention relates to methods and compositions for the treatment or alleviation of Alzheimer's disease and of other conditions related to abnormal protein aggregation. In particular, the invention relates to methods and compositions for the immunotherapy of Alzheimer's disease, Parkinson's disease, and cataract. In one aspect the invention provides a method of prophylaxis, treatment or alleviation of a condition characterized by pathological aggregation and accumulation of a specific protein associated with an immunizing-effective dose of one or more tyrosine cross-linked compounds, and optionally also comprising copper ions complexed to the compound. Alternatively passive immunization against a tyrosine cross-linked compound may be used. Prophylactic or therapeutic compositions and diagnostic methods are also disclosed and claimed. |
US08318166B2 |
Ligands of HVEM for treating hematologic malignancies
The present invention relates to ligands of HVEM for the treatment of hematologic malignancies, in particular Chronic lymphocytic leukaemia, and for the treatment of autoimmune diseases. |
US08318163B2 |
Anti-pan neuropilin antibody and binding fragments thereof
The invention provides crystal structures of neuropilin 1 (Nrp1) and neuropilin 2 (Nrp2) fragments alone and in complex with anti-neuropilin antibodies, and method for their use. The invention further provides anti-Nrp antibodies and methods for their therapeutic applications. |
US08318161B2 |
Anti-oxidized LDL antibody formulation
A formulation comprising a therapeutically effective amount of an antibody, optionally, not subjected to prior lyophilization, a buffer maintaining the pH in the range from about 4.5 to about 6.5, and an optional surfactant is described, along with uses for such a formulation. |
US08318156B2 |
Anti-cocaine compositions and treatment
Embodiments of the invention disclosed herein generally relate to anti-cocaine therapeutics. Specifically, some embodiments of the invention relate to highly efficient, thermostable, and long-lasting cocaine esterase (CocE) mutants that can protect against the toxic and reinforcing effects of cocaine in subjects. Provided herein are mutant CocE polypeptides displaying thermostable esterase activity. Also provided are methods of treating cocaine-induced conditions in a subject in need via administration of mutant CocE as well as methods for high-throughput screening of candidate esterase polypeptides. |
US08318155B2 |
Nucleic acid cleaving agent
A nucleic acid cleaving agent having a cleaving activity specific to a desired cleavage site in a nucleic acid such as large DNA, which comprises (1) a nucleic acid cleaving moiety, and (2) at least two zinc finger proteins bound to the nucleic acid cleaving moiety, wherein at least one of the zinc finger proteins can specifically bind to a nucleotide sequence located upstream from the target cleavage site, and at least one of the remaining zinc finger proteins can specifically bind to a nucleotide sequence located downstream from the target cleavage site. |
US08318151B2 |
Lactobacillus rhamnosus NCC4007, a probiotic mixture and weight control
The present invention generally relates to the field of weight management and obesity. In particular the present invention relates to the use of probiotics in combination with prebiotics to treat or prevent obesity. One embodiment of the present invention relates to the use of Lactobacillus rhamnosus NCC 4007 in combination with a specific probiotic mixture for the preparation of a composition to support weight management, promote weight loss and/or to treat obesity. |
US08318147B2 |
Use of IL-29 for treating a dengue virus infection
IL-28A, IL-28B, IL-29, and certain mutants thereof have been shown to have antiviral activity on a spectrum of viral species. Of particular interest is the antiviral activity demonstrated on viruses that infect liver, such as hepatitis B virus and hepatitis C virus. In addition, IL-28A, IL-28B, IL-29, and mutants thereof do not exhibit some of the antiproliferative activity on hematopoietic cells that is observed with interferon treatment. Without the immunosuppressive effects accompanying interferon treatment, IL-28A, IL-28B, and IL-29 will be useful in treating immunocompromised patients for viral infections. |
US08318145B2 |
Multi-arm polymer prodrugs
Provided herein are water-soluble prodrugs. The prodrugs of the invention comprise a water-soluble polymer having three or more arms, at least three of which are covalently attached to an active agent, e.g., a small molecule. The conjugates of the invention provide an optimal balance of polymer size and structure for achieving improved drug loading, since the conjugates of the invention possess three or more active agents releasably attached to a multi-armed water soluble polymer. The prodrugs of the invention are therapeutically effective, and exhibit improved properties in-vivo when compared to unmodified parent drug. |
US08318140B2 |
Methods for promoting hair growth
The present invention relates to methods of promoting hair growth in a patient. The method comprises administering to a patient in need thereof a sugar compound that is converted to a glycosaminoglycan in the patient, a primary antioxidant component, at least one amino acid component, and one or more transition metals. |
US08318135B2 |
Antagonist of ligands and uses thereof
The invention provides multivalent ligand binding agents (traps) for members of the TGF-β superfamily and polypeptide linkers and methods for making and using such constructs. The traps may be used as therapeutic or diagnostic (imaging or non-imaging) agents for diseases/disorders caused by over-production/activity of the target ligand. In an embodiment of the invention there is provided a multivalent binding agent with affinity for a member of the TGF-β superfamily, the agent having the general structure I: ( |
US08318132B2 |
Imaging agents for detecting neurological dysfunction
Disclosed here in are compounds and methods of diagnosing Alzheimer's Disease or a predisposition thereto in a mammal, the method comprising administering to the mammal a diagnostically effective amount of a radiolabeled compound, wherein the compound is selected from the group consisting of radiolabeled flavones, coumarins, carbazoles, quinolinones, chromenones, imidazoles and triazoles derivatives, allowing the compound to distribute into the brain tissue, and imaging the brain tissue, wherein an increase in binding of the compound to the brain tissue compared to a normal control level of binding indicates that the mammal is suffering from or is at risk of developing Alzheimer's Disease. |
US08318126B2 |
Methods of making metal oxide nanostructures and methods of controlling morphology of same
The present invention includes a method of producing a crystalline metal oxide nanostructure. The method comprises providing a metal salt solution and providing a basic solution; placing a porous membrane between the metal salt solution and the basic solution, wherein metal cations of the metal salt solution and hydroxide ions of the basic solution react, thereby producing a crystalline metal oxide nanostructure. |
US08318125B2 |
Method for activating catalyst for chlorine production
A catalyst having decreased activity is subjected to a contact treatment with a reducing gas containing carbon monoxide and/or hydrogen. Also, the catalyst can be effectively activated by being treated by contacting with an oxidizing gas after having been treated by contacting with the reducing gas. As the catalyst for production of chlorine, a ruthenium catalyst, particularly a catalyst containing ruthenium oxide is suitably activated. |
US08318120B2 |
Process for the surface modification of particles
A method for the preparation of functionalized particles includes providing a feedstock made of particles, a surface treatment agent reactive with the particles, and solvent. The feedstock is exposed to microwave radiation to heat the feedstock and react the particles with the surface treatment agent to provide the functionalized particles in less than about 60 minutes. |
US08318114B2 |
Composition for treating acid gas
This invention provides novel compositions comprising substituted polyamines as acid gas scrubbing solutions and methods of using the compositions in an industrial system. The invention relates to the use of such polyamine compounds in industrial processes to remove acidic contaminants from natural and industrial fluid streams, such as natural gas, combustion gas, natural gas, synthesis gas, biogas, and other industrial fluid streams. The compositions and methods of the invention are useful for removal, absorption, or sequestration of acidic contaminants and sulfide contaminants including CO2, H2S, RSH, CS2, COS, and SO2. |
US08318113B2 |
Purification of metals
A solid composition comprises: —MnO2; and—a compound represented by the general formula (I) wherein: R is a polymer; each Y is independently a hydrogen or a negative charge; Z is either hydrogen or is not present; each n is independently 1, 2, 3, 4, 5 or 6; wherein the MnO2 is bound to the compound of formula (I) so as to coat the surface thereof. Such a composition may be used for the separation of polyvalent metal species, such as Mo, from one or more accompanying impurities. |
US08318107B2 |
Apparatus and method for specimen suitability testing
Disclosed herein are a system for collecting a sample and optionally detecting or analyzing an electrical property thereof, the method comprising: means for obtaining a sample in a sample container; means for directing the sample into a sensing chamber in fluid communication with the sample container, the sensing chamber comprising a plurality of sensing chamber electrodes positioned at the sensing chamber and configured to be in contact with the sample when the sample is directed into the sensing chamber; means for applying an electrical signal to the sample with a read-out analyzer via the plurality of sensing chamber electrodes; the plurality of sensing chamber electrodes in operable communication with the read-out analyzer; and means for detecting the effect of the sample on the electrical signal, thereby determining an electrical property of the sample. |
US08318106B2 |
Analysis system for analyzing a sample on a test element
The invention relates to an analysis system for analyzing a sample on a test element. The system has an analysis unit for generating a signal as a function of an analyte contained in a sample, and a detection unit for detecting the signal. The analysis system further includes a test element holder into which the test element can be reversibly introduced and in which it can be positioned relative to the analysis unit and the detection unit. The test element contains at least one guide element, which is suitable for laterally guiding the test element, so that the test element in the test element holder is held and guided only on an outer region of the test element, and an inner region of the test element introduced into the test element holder remains free. The test element contains a sample application site in the inner region. |
US08318105B2 |
Systems and methods for biomarker analysis
Systems and methods of biomarker analysis. In at least one embodiment of a system for determining the therapeutic potential of a therapeutic compound the present disclosure, the system comprises a detection platform, a computer database capable of receiving a plurality of binding characteristics, a processor operably coupled to the computer database and the detection platform. In at least one embodiment, the processor has and executes a software program operational to determine a binding characteristic of the detection agent and a stabilized diagnostic agent in each of the plurality of detection sites, compare the binding characteristic among each of the plurality of detection sites, wherein the comparison of binding characteristics is capable of determining the stabilizing agent with the greatest effect on the binding characteristic between the detection agent and the diagnostic agent, generate a binding record using the compared binding characteristics, and deliver the binding record to a recipient. |
US08318100B2 |
Reactor vessels with pressure and heat transfer features for producing hydrogen-based fuels and structural elements, and associated systems and methods
Reactor vessels with pressure and heat transfer features for producing hydrogen-based fuels and structural elements, and associated systems and methods. A representative reactor system in accordance with a particular embodiment includes a first reaction zone and a heat path positioned to direct heat into the first reaction zone, a reactant source coupled to the first reaction zone, and a first actuator coupled to cyclically pressurize the first reaction zone. The system can further include a second reaction zone in fluid communication with the first, a valve coupled between the first and second reaction zones to control a flow rate therebetween, and a second actuator coupled in fluid communication with the second reaction zone to cyclically pressurize the second reaction zone. A first heat exchanger is positioned to direct heat from a first product leaving the first reaction zone to a reactant entering the first reaction zone, and a second heat exchanger is positioned to direct heat from a second product leaving the second reaction zone to the reactant entering the first reaction zone. A controller is coupled to the first and second actuators and is programmed with instructions that, when executed, control the first and second actuators in a coordinated manner based at least in part on a flow rate of the second product from the second reaction zone. |
US08318096B2 |
Biological sample measurement apparatus
A wireless blood glucose meter is a battery-powered apparatus to communicating wirelessly with a portable terminal, and includes a blood glucose level detector that measures a blood glucose level, a transmitter that transmits the blood glucose level measured by the blood glucose level detector to the portable terminal, a receiver that receives a response signal sent from the portable terminal in response to the transmission of the blood glucose level by the transmitter to the portable terminal, and a voltage monitor that monitors the output voltage of the battery. A transmission control circuit changes the transmission method used by the transmitter on the basis of the output voltage of the battery as detected by the voltage monitor. |
US08318095B2 |
Apparatus for execution of treatment operations in connection with colouring of tissue specimens on object glasses
An apparatus for automatic execution of different treatment operations in connection with staining of tissue specimens on microscope slides, wherein the apparatus (1) comprises a loading station (2) for microscope slides (7) with tissue specimens, a number of reagent stations (3) for staining of the tissue specimens on supplied microscope slides, a conveyor (5) for transfer of microscope slides (7) between the stations (3) in accordance with a staining program, an unloading station (10) for treated microscope slides, and a control unit (19) for controlling the treatment operations in accordance with a data program. The apparatus comprise a photo station (25) with a digital camera (26) for automatic photographing with a background light source of the finished treated tissue specimens on supplied microscope slides (7). The camera is connected to the control unit (19) of the apparatus and the control unit is arranged to store the picture of each individual tissue specimen and information which is located on the relevant microscopic slide (7) and preferably also information about the staining program and status of reagents at the reagent stations (3) for automatic transmission of the information to a place for result analysis. |
US08318094B1 |
Substrate analysis systems
This invention provides systems for analyzing substrates. Also provided by the invention are improved optical systems for enhanced multiplex illumination, optical systems with compact multi-wavelength illumination architectures, optical systems for enhanced detection of optical signals, and optical systems for reduced autofluorescence background noise. |
US08318093B2 |
Magnetic nanoparticles, magnetic detector arrays, and methods for their use in detecting biological molecules
Magnetic nanoparticles and methods for their use in detecting biological molecules are disclosed. The magnetic nanoparticles can be attached to nucleic acid molecules, which are then captured by a complementary sequence attached to a detector, such as a spin valve detector or a magnetic tunnel junction detector. The detection of the bound magnetic nanoparticle can be achieved with high specificity and sensitivity. |
US08318087B2 |
Microwave accelerated assays
The present invention provides for increasing fluorescence detection in surface assay systems while increasing kinetics of a bioreaction therein by providing low-power microwaves to irradiate metallic materials within the system in an amount sufficient to increase heat thereby affecting the kinetics of a bioreaction therein. |
US08318083B2 |
Cast heat-resistant austenitic steel with improved temperature creep properties and balanced alloying element additions and methodology for development of the same
The present invention addresses the need for new austenitic steel compositions with higher creep strength and higher upper temperatures. The new austenitic steel compositions retain desirable phases, such as austenite, M23C6, and MC in its microstructure to higher temperatures. The present invention also discloses a methodology for the development of new austenitic steel compositions with higher creep strength and higher upper temperatures. |
US08318080B2 |
Device and method for cooling hot strip
A device and a method for cooling a hot strip capable of uniformly cooling the hot-rolled steel strip from the leading end to the trailing end thereof during cooling of the steel strip using cooling water are provided. A cooling device 10 includes a plurality of tubular nozzles 15 inclined so as to eject rod-like flows of cooling water to a steel strip 12 at an ejecting angle θ in a traveling direction of the steel strip 12 and a pinch roller 11 disposed downstream of the tubular nozzles, the steel strip 12 to be nipped between the pinch roller 11 and a table roller 8. |
US08318078B2 |
Asymmetric stent delivery system with proximal edge protection and method of manufacture thereof
A balloon catheter stent deployment system is disclosed wherein a balloon catheter is provided and a tubular stent is crimped onto a distal portion of the balloon with a distal end of the stent in close proximity to a point where the distal end of the balloon is attached to the inner tube of the catheter. A proximal section of the balloon extending from a proximal end of the stent to a point where the proximal end of the balloon is attached to the outer shaft of the catheter remains uncovered by the stent and, has a larger uninflated outer diameter than the crimped stent. Thus, in some embodiments, the proximal section of the balloon provides a protective cone for the proximal end of the stent to help resist frictional forces from disengaging the stent from the balloon in the event the balloon catheter and stent are withdrawn back into a guide catheter during a procedure. A stepped enclosure is also disclosed which is used in a disclosed fabrication method to allow the proximal section of the balloon to be inflated after the stent is crimped onto the distal section of the balloon. |
US08318076B2 |
Selective deposition modeling methods for improved support-object interface
There are provided method and apparatus for the forming of three-dimensional objects in a layered fashion, wherein improvements are made to the support structure to improve the quality of the resulting three-dimensional objects. The support structure may include encapsulation along the interface boundary of the support-object interface to prevent or reduce the likelihood of separation of the build material, that forms the three-dimensional object, from the support material, that forms the support structure, or vice versa. The support structure may also or alternatively include both a porous support structure and a solid support structure to prevent or reduce the likelihood of separation of the support structure from the build platform and to improve the quality of the down-facing surfaces of the three-dimensional object. Methods are also provided for selectively depositing the support material and build material and for encapsulating the interface boundary with support material. |
US08318075B2 |
Compression moulding apparatus, methods and item
An apparatus comprises a molding unit having a punch and a mold cavity movable along a path between an open position in which said punch and said mold cavity are distanced apart from each other to receive a dose of plastics therebetween, and a closed position in which said punch and said mold cavity interact to form an item by pressing said dose, said punch being kept not above said cavity along said path. |
US08318073B2 |
Non-slip activation members
A mechanical activation system has a first activation member, a second activation member, an activation zone, and a non-slip zone. The first activation member has a first plurality of teeth, and the second activation member has a second plurality of teeth. The first plurality of teeth is capable of intermeshing with the second plurality of teeth. The activation zone includes a first portion of the first plurality of teeth and a first portion of the second plurality of teeth. The first portion of the first plurality of teeth and the first portion of the second plurality of teeth include teeth having continuous tips. The first non-slip zone includes a second portion of the first plurality of teeth or a second portion of the second plurality of teeth. The second portion includes a tooth having a discontinuous tip. |
US08318069B2 |
Method for securing a machine element
A method is disclosed in which a pressurized fluid presses an axial abutment surface against a first machine element in the axial direction to thereby fix the axial position of the first machine element and/or to thereby set a desired axial pre-loading of the first machine element. The fluid is then solidified to permanently maintain the axial position and/or the axial pre-loading of the first machine element. A clamp is disclosed that permanently affixes the first machine element relative to a second machine element using this method. An apparatus comprising the first machine element axially fixed relative to the second machine element by the clamp is also disclosed. |
US08318068B2 |
Method for producing a connection between composite parts
A method for joining together constructional parts which are made of a composite material and extend transversely to one another, such as a flange and a web of a profile, includes the steps of: placing the constructional parts in the desired position with respect to one another so as to form a connecting region in which one of the constructional parts abuts against or in proximity to the other constructional part, causing a thermoplastic material to flow out into the connecting region, fusing together the constructional parts under the influence of heat and pressure. |
US08318067B2 |
Resin transfer moulding process for an article containing a protective member
A resin transfer molding process for an article incorporating a protective insert of polymer material such as polyether ether ketone (PEEK). A piece of PEEK material is cut and thermoformed to the required shape and then placed in position in a mold. A bead of elastomer material is formed around the edge of the insert to seal it against an internal wall of the mold in order to prevent resin tracking between the mold and insert faces during subsequent injection into the mold. |
US08318061B2 |
Mold temperature control circuit of injection molding device and method for discharging heating medium
In a mold temperature control circuit of an injection molding device, such a molding cycle is repeated that, prior to injection of a resin, a heating-use medium is returned to molds and heated to a temperature suitable for resin injection, after injection of the resin, the heating-use medium is switched to a cooling-use medium, thereby the cooling-use medium is returned to the molds and cooling is conducted to give a temperature equal to or lower than a temperature at which the resin is solidified. In the mold temperature control circuit of the injection molding device, a junction piping is able to commonly use the respective supply pipings of the heating-use medium, the cooling-use medium and the scavenging compressed air to the molds and the respective discharge pipings thereof, and there is provided mold bypass piping coupling the supply-side junction piping of the heating medium with the discharge-side junction piping, a mold bypass on-off valve, a passed heating medium sensor, a mold-temperature adjusting control device which stores a mold temperature determination program and a passed heating medium determination program. |
US08318059B2 |
Stabilization of poly(oxyalkylene) containing polymeric materials
The present invention provides a method for producing a medical device, preferably an ophthalmic device, more preferably a contact lens, made of a stabilized poly(oxyalkylene)-containing polymeric material. The method of the invention comprises the steps of: curing, in a mold, a composition comprising (a) a prepolymer having at least one poly(oxyalkylene) unit, (b) a biocompatible organic multi-acid or biocompatible salt thereof in an amount sufficient to improve the stability of the poly(oxyalkylene)-containing polymer made from the composition, (c) optionally a photoinitiator or a thermal initiator, and (d) optionally one or more vinylic monomers, to form the medical device being less susceptible to oxidative degradation; and removing the medical device from the mold. |
US08318056B2 |
Optical sheet manufacturing method
An optical sheet having both a light condensing function and a light diffusing function in a single sheet is to be provided. When a transparent support (18) on which a curable resin coat layer (38) is formed is wound around a zigzag-faced roller (32) on which the reversed pattern of convex-concave patterns is formed to transfer the reversed pattern of the zigzag-faced roller (32) to the resin coat layer (38), gas is blown from a gas jet nozzle (50), immediately before winding the transparent support (18) around the zigzag-faced roller (32), into a gap between the resin coat layer (38) and the surface of the zigzag-faced roller. |
US08318055B2 |
Methods for formation of an ophthalmic lens precursor and lens
This invention discloses methods for generating one or both of an ophthalmic lens precursor with at least a portion of one surface free-formed from a Reactive Mixture. In some embodiments, an ophthalmic lens precursor is formed on a substrate with an arcuate optical quality surface via a source of actinic radiation controllable to cure a definable portion of a volume of Reactive Mixture. |
US08318052B2 |
Diketopyrrolopyrrole cocrystals with high transparency
The present invention relates to a pigment composition composed of compounds of the formula (I), (II) and (III) with a novel crystal modification, to their preparation and to the use of this novel product as a pigment. For many applications of organic pigments, for example the coloring of metallic lacquers or the use thereof in color filters, a very high transparency is required. To produce color filters, for example, particularly fine pigments are used, in order to substantially rule out the particle scattering which leads to a lowering of the contrast ratio. The commercially available products, however, do not always meet all requirements of the art. More particularly, there was a need for improvement with regard to the transparency and the associated fineness of the pigment crystals, and also the color purity (chroma). |
US08318050B2 |
Processes for polymeric precursors for caigas aluminum-containing photovoltaics
This invention relates to processes for compounds, polymeric compounds, and compositions used to prepare semiconductor and optoelectronic materials and devices including thin film and band gap materials. This invention provides a range of compounds, polymeric compounds, compositions, materials and methods directed ultimately toward photovoltaic applications, transparent conductive materials, as well as devices and systems for energy conversion, including solar cells. In particular, this invention relates to polymeric precursor compounds and precursor materials for preparing photovoltaic layers. In particular, this invention relates to molecular precursor compounds and precursor materials for preparing photovoltaic layers including CAIGAS. |
US08318041B2 |
Stable sediment dispersion, method for production and use thereof
The present invention relates to a stable sediment dispersion which can be used above all as electrorheological (ERF) and/or magnetorheological fluid (MRF), a method for production thereof and also use thereof. |
US08318040B2 |
Refrigerator oil and working fluid composition for refrigerating machine
The refrigerating machine oil of the invention is characterized by comprising an ester of a polyhydric alcohol and fatty acids with a content of a C10-C13 branched fatty acid of 50% by mole or greater. The working fluid composition for a refrigerating machine of the invention is characterized in that the working fluid composition comprises an ester of a polyhydric alcohol and fatty acids with a content of a C10-C13 branched fatty acid of 50% by mole or greater, and a refrigerant. |
US08318034B2 |
Surface processing method
In a surface processing method for processing a surface of a member made of silicon carbide (SiC) and having a fragmental layer on a surface thereof, the surface of the member having the fragmental layer is modified into a dense layer to reduce the number of particles generated from the surface of the member when the member is applied to a plasma processing apparatus. Here, the SiC of the surface of the member is recrystallized by heating the fragmental layer. |
US08318033B2 |
Conductive tape and method for making the same
The present invention relates to a conductive tape. The conductive tape includes a adhesive layer and a plurality of carbon nanotubes. The adhesive layer has a first surface and an opposite second surface. The carbon nanotubes are substantially embedded in parallel in the adhesive layer and perpendicular to the first surface and the second surface. Each of the carbon nanotubes has two opposite ends extending out of the two opposite surfaces of the adhesive layer respectively. Further, a method for making the above-described conductive tape is also included. |
US08318030B2 |
Magnetic device definition with uniform biasing control
A method of fabricating a magnetic device is described. A mask removing layer is formed on a layered sensing stack and a hard mask layer is formed on the mask removing layer. A first reactive ion etch is performed with a non-oxygen-based chemistry to define the hard mask layer using an imaged layer formed on the hard mask layer as a mask. A second reactive ion etch is performed with an oxygen-based chemistry to define the mask removing stop layer using the defined hard mask layer as a mask. A third reactive ion etch is performed to define the layered sensing stack using the hard mask layer as a mask. The third reactive ion etch includes an etching chemistry that performs at a lower etching rate on the hard mask layer than on the layered sensing stack. |
US08318026B2 |
Grit chamber and a method for controlling the same
A system for controlling the sedimentation of sand or grit particles suspended in waste water contained in a grit chamber by determining the temperature of water contained in the grit chamber and by operating a turbulence creating means on the basis of the water temperature. A method of controlling the sedimentation of sand and grit particles suspended in waste water contained in a grit chamber, by determining the temperature of water contained in the grit chamber and by operating a turbulence creating means on the basis of the water temperature. |
US08318024B2 |
System and method for distribution of fluid a multistage column
The present invention consists of a device for distributing and collecting fluids at the outlet from an upstream granular bed in a multistage column having a plurality of granular beds, said device comprising a deflector, which can equalize the trajectories of the fluid stream lines from the outlet from the mixing chamber to the downstream bed of granular solid. |
US08318022B2 |
Wafer-shaped hollow fiber module for in-line use in a piping system
A wafer-shaped hollow fiber module adapted for in-line use in a piping system. The piping system may include two standard bolted flange connections, and at least one wafer-shaped hollow fiber module sealed between the two standard bolted flange connections. The wafer shaped hollow fiber module includes: a cylindrical housing having an open end and a closed end having a first sealing surface and an inlet port; at least one side port through the cylindrical housing; an end cap united to the open end having a second sealing surface and an outlet port. |
US08318021B2 |
Water filtration system
A water or liquid substance filtration device is disclosed which removes microorganisms and organic contamination and sterilizes the containers and water lines after the unit. The unit is portable, or can be mounted stationary. The unit has a five-stage filtration and sterilization system controlled by an independent onboard computer system that can link to a central computer system to keep track of all independent units. The unit will physically filter out of the water contaminants that can be reused, destroyed, or flushed down a safe drain. It can also be modified to filter for a certain size of particulate, making recovery of certain substances possible. The unit has a self-diagnostic system that can determine if the unit is operating properly and can shut down a part thereof if one of the capillary units fails. The system is hydrophilic, can run at low pressures and can be designed from low to extremely high volumes. The unit uses ozone to disinfect containers and water lines. |
US08318020B2 |
Washing method and apparatus of separation membrane
When a separation membrane (3) is washed with a chemical solution that is a sodium hypochlorite solution, which has a high concentration, diluted with membrane treated water stored in a chemical solution tank (6), an ammonic nitrogen concentration in membrane-treated water is monitored with a monitoring device (9), and a control device (8) controls a chemical solution dosing pump (7) using the concentration measured by the device (9) to adjust a dilution rate. Thereby, even when water quality of membrane-treated water varies, a sodium hypochlorite concentration in backwashing water can be retained constant, and fluctuation in the chemical washing effect can be prevented. |
US08318015B2 |
Stormwater filtration systems
A stormwater filtration system suitable for treatment of stormwater runoff in a developed environment uses a primary treatment bay that includes a filtration bed with live plant matter. A second treatment bay treats water that exceeds the maximum throughput of the primary bay. A reservoir stores treated runoff to water the plants during dry weather. Removable trays on the surface of the primary filtration bed provide plants suitable for ground cover. Additional bays expand the filtration bed throughput and accommodate extended root systems. A flow control may be provided for the primary treatment bay. |
US08318014B2 |
Reactor comprising a stack of filter plates
A reactor includes a tubular-shaped housing in which a stack of filter plates can be rotationally arranged. The cross-sectional area of the reactor container is, in the region of the stack of filter plates, a maximum of 40% greater than the cross-sectional area of the stack of filter plates. The longitudinal extension of the reactor housing is a multiple of the longitudinal extension of the stack of filter plates, such that inside the reactor, adjacent to the stack of filter plates, additional processing devices can be arranged. The rotating stack of filter plates ensures that the entire reactor is cross-flown in an intensive manner. |
US08318013B2 |
Staged membrane system for gas, vapor, and liquid separations
The present invention involves the use of a multi-stage membrane system for gas, vapor, and liquid separations. In this multi-stage membrane system, high selectivity and high permeance or at least high selectivity polybenzoxazole membranes or cross-linked polybenzoxazole membranes are applied for a pre-membrane or both the pre-membrane and the secondary membrane. A primary membrane can be from conventional glassy polymers. This multi-stage membrane system can reduce inter-stage compression cost, increase product recovery and product purity for gas, vapor, and liquid separations. It can also save the cost compared to the system using all the high cost polybenzoxazole membranes or cross-linked polybenzoxazole membranes. |
US08318012B2 |
Barge oil skimmer
An oil skimming water vessel having a hull and deck forming one or more interior compartments, wherein the hull comprising a bow or forward section, a mid-section, a stern or aft section, and an oil skimmer assembly, and wherein either or both of the bow or aft section constructed having a rake bottom shell. The oil skimmer assembly having first and second separated side walls (SKEG) extending vertically down from the rake bottom shell, a skimmer bottom plate extending between and affixed at the lower end sections of each of the side walls (SKEG) wherein the skimmer bottom plate having at least one discharge opening in its leading edge section, and a weir plate assembly. The rake bottom shell having at least one standpipe opening to which a standpipe attaches and extends vertically to a corresponding vessel deck opening. The weir plate assembly including a weir plate extending upward from the skimmer bottom plate between and affixed to the first and second side walls, the weir plate positioned between the discharge openings and the one or more standpipe openings. The weir plate with the side walls, the skimmer bottom plate, and the rake bottom shell forming an entrance to receive skimmed oil-containing water and a rear compartment positioned rearward of the weir plate to collect the skimmed oil-containing water passing over the top edge of the weir plate. |
US08318011B2 |
Portable drinking water purification device
A portable water disinfecting and purification apparatus comprising a first chamber into which water to be purified may be drawn by suction or negative pressure, a second chamber into which the water from the first chamber can be forced by a pumping action or positive pressure, whereby the water is initially passed across a pre-filter secured over the inlet to the first chamber and having a very small pore size and an inner cavity in which a disinfecting agent is place to filters most contaminants before the water is drawn into said filtering device, and once in the first holding chamber the water is isolated and may be further treated with a disinfectant agent, and then is passed though at least additional filtering substance including an activated carbon or nano-filter. |
US08318008B1 |
Modular individual wastewater nutrient removal system
A modular, on-site, wastewater treatment system removes total nitrogen, phosphorus, BOD, and TSS. A flow equalization module provides a constant flow rate to the system eliminating the adverse effects from variations in flow rate throughout the day. Treatment modules are similarly sized to provide a compact, modular system. The nitrification module is a fixed-film, flooded packed bioreactor to facilitate bioconversion of ammonia to nitrate. Aeration of the module provides the oxygen needed for the bioconversion as well prevents clogging of the film. Solids from the nitrification process are removed in a first cone-shaped settling tank. De-nitrification where nitrate is converted to nitrogen gas takes place in an anaerobic fixed-film bioreactor. Carbon-based bio-film carriers provide a carbon source for de-nitrification. A final cone-shaped settling tank separates solids from the treated wastewater. Additional modules to address removal of phosphorous or other contaminants can be added to the modular system. |
US08318007B2 |
Ultraviolet radiation lamp and source module and treatment system containing same
The invention relates to an ultraviolet radiation lamp. The lamp comprises a substantially sealed cavity comprising a mercury-containing material; a filament disposed in the sealed cavity; and an electrical control element in contact with the filament, the electrical control element configured to adjust or maintain a temperature of the mercury-containing material with respect to a prescribed temperature. Such a constructions allows the present ultraviolet radiation lamp to be operated at optimal efficiency without the need to use additional components to add heat to and/or remove heat from the mercury-containing material. |
US08318004B2 |
Hydrocarbon treatment method and apparatus
A method and apparatus for producing a treated hydrocarbon containing stream for use as a feed to a hydrogen plant having a steam methane reformer in which an untreated hydrocarbon containing stream is introduced into two reaction stages connected in series to hydrogenate olefins and to convert organic sulfur species to hydrogen sulfide. The second of the two stages can also be operated in a pre-reforming mode to generate additional hydrogen through introduction of the oxygen and steam into such stage. A sulfur tolerant catalyst is used in both stages to promote hydrogenation and oxidation reactions. Sulfur is removed between stages by adsorption of the hydrogen sulfide to prevent deactivation of the catalyst in the second of the stages that would otherwise occur during operation of the second reaction stage in a pre-reforming mode of operation. |
US08318003B2 |
Process for catalytic conversion of Fischer-Tropsch derived olefins to distillates
The invention provides a low aromatic producing process for catalytical conversion of Fisher-Tropsch derived olefins to distillates (COD), which process includes the step of contacting Fisher-Tropsch derived olefins with a zeolite type catalyst at pressures of more than 50 barg. |
US08318000B2 |
Method of producing a crude product
A method of producing a crude product from a hydrocarbon feed is provided. A hydrocarbon feed is contacted with a catalyst containing a Col. 6-10 metal or compound thereof to produce the crude product, where the catalyst has a pore size distribution with a median pore diameter ranging from 105 Å to 150 Å, with 60% of the total number of pores in the pore size distribution having a pore diameter within 60 Å of the median pore diameter, with at least 50% of its pore volume in pores having a pore diameter of at most 600 Å, and between 5% and 25% of its pore volume in pores having a pore diameter between 1000 Å and 5000 Å. |
US08317993B2 |
Plating method and apparatus
A plating apparatus has a steam treatment chamber configured to perform a steam treatment using steam on a surface of a substrate, and a plating chamber configured to plate the surface of the substrate subjected to the steam treatment. The plating apparatus also has an acid treatment chamber configured to bring the surface of the substrate subjected to the steam treatment into contact with an acid liquid. The plating apparatus includes a frame housing the steam treatment chamber, the acid treatment chamber, and the plating chamber. |
US08317990B2 |
Droplet actuator loading and target concentration
A droplet actuator and method of providing a droplet comprising an target substance on the droplet actuator, and including discrete flow and continuous flow functionality. Discrete flow function is controlled by electrodes arranged for conducting droplet operations on a substrate surface. The continuous flow function includes a fluid path arranged for flowing a fluid therethrough. The discrete flow and continuous flow functions may be by a barrier, including a second fluid path through the barrier. The continuous flow function may include a capture surface comprising a component having an affinity for the target substance. Methods of the invention may include flowing a fluid comprising the target substance through the fluid path; capturing the target substance on the capture surface; and forming a droplet in the discrete flow region via the second fluid path and the electrodes comprising the captured target substance. |
US08317989B2 |
Electrochemical sensor
An electrochemical sensor is provided that includes a housing having an outer wall, an axial bore circumscribed by the outer wall, and a barrier wall that aids in defining a reference cavity. The housing further including a plurality of cross members in spaced relation to one another disposed between the axial bore and the outer wall, each cross member defining an aperture. A junction plug is disposed at the distal end of the housing. The junction plug comprises a porous material that enables ionic flow through the junction plug. The sensor enables ionic communication between the target fluid and the reference electrode within the reference cavity through the apertures of the plurality of cross members. In this manner, the sensor provides generally a long, tortuous flow path, or salt bridge, between the target fluid and the reference electrode, resulting in a high resistance factor for the sensor. |
US08317987B2 |
Non-permeable substrate carrier for electroplating
One embodiment relates to a substrate carrier for use in electroplating a plurality of substrates. The substrate carrier comprises a non-conductive carrier body on which the substrates are to be held. Electrically-conductive lines are embedded within the carrier body, and a plurality of contact clips are coupled to the electrically-conductive lines embedded within the carrier body. The contact clips hold the substrates in place and electrically couple the substrates to the electrically-conductive lines. The non-conductive carrier body is continuous so as to be impermeable to flow of electroplating solution through the non-conductive carrier body. Other embodiments, aspects and features are also disclosed. |
US08317983B1 |
Laser ablation for the synthesis of carbon nanotubes
Single walled carbon nanotubes are produced in a novel apparatus by the laser-induced ablation of moving carbon target. The laser used is of high average power and ultra-fast pulsing. According to various preferred embodiments, the laser produces and output above about 50 watts/cm2 at a repetition rate above about 15 MHz and exhibits a pulse duration below about 10 picoseconds. The carbon, carbon/catalyst target and the laser beam are moved relative to one another and a focused flow of “side pumped”, preheated inert gas is introduced near the point of ablation to minimize or eliminate interference by the ablated plume by removal of the plume and introduction of new target area for incidence with the laser beam. When the target is moved relative to the laser beam, rotational or translational movement may be imparted thereto, but rotation of the target is preferred. |
US08317980B2 |
Reactor for converting waste materials into fuel, a feeding system for feeding waste materials into the reactor, and methods for converting waste materials into fuel
A reactor having a shaft protruding through one end, a fuel output tube protruding through a second end, shovels housed inside, and a discharge tube, is provided. A first end of the discharge tube is inside of the reactor and the second end protrudes out of the fuel output tube. A helix thruster can be inside the discharge tube and have a driver shaft with a first gear inside of the reactor. The reactor can also include a residue collector and a fork. The fork can be disposed on a driven shaft including a second gear, which engages the first gear of the helix thruster. A system for feeding materials into the reactor is also disclosed as well as methods of converting waste plastic or rubber into fuel using the reactor. |
US08317978B1 |
Nitriding of carbon nanotubes
A method of fabricating a non-brittle, carbon nanopaper from single wall, multiwall, and combination thereof, from carbon nanotubes, using a vacuum deposition, high temperature annealing, and polystyrene polymer rinse process; which nanopaper can be nitrided by either a plasma-enhanced chemical vapor deposition (PECVD) process, or an by an electrochemical method, to obtain a useful chemically functionalized substrate, a substrate containing metastable N4, N8, and longer chain polymeric nitrogen clusters. Such nitrided carbon nanopaper can be used to enhance the ballistic performance of gun propellants, while reducing gun barrel wear and erosion thereof. |
US08317977B2 |
Methods of forming a reinforced parchmented nonwoven product
This specification is generally related to reinforced, parchmented paper, composite, reinforced parchmented paper and methods of manufacture thereof. The reinforced, parchmented paper may be used to form a sausage casing. |
US08317972B2 |
Method and apparatus for optical fiber coating removal
A method for removing a protective coating material from a portion of an optical fiber including a glass optical fiber having an outer surface surrounded by said protective coating material, said method comprising the steps of: (i) providing a fiber collection and support device having: (a) a coarse conical fiber collector having an input port and (b) a fine fiber centering collector including a fiber tube having an output port, said input port is larger then said output port; (ii) providing the fiber threaded through the course conical collector into the fiber collection tube of the fine fiber centering collector; (iii) contacting the fiber, as it exits from the output port of the fiber collection tube of the fiber collection and support device, with a stream of hot gas; and (iv) directing a stream of a hot gas onto the protective coating material that is to be removed. |
US08317966B2 |
Apparatus for substantially uniform fluid flow rates relative to a proximity head in processing of a wafer surface by a meniscus
Conditioning fluid flow into a proximity head is provided for fluid delivery to a wafer surface. An upper plenum connected to a plurality of down flow bores is supplied by a main bore. The down flow bores provide fluid into the upper plenum, and a resistor bore is connected to the upper plenum. The resistor bore receives a resistor having a shape so as to limit flow of the fluid through the resistor bore. A lower plenum connected to the resistor bore is configured to receive fluid from the resistor bore as limited by the resistor for flow to a plurality of outlet ports extending between the lower plenum and surfaces of the head surface. Fluid flowing through the upper plenum, the resistor bore with the resistor and the lower plenum is substantially conditioned to define a substantially uniform fluid outflow from the plurality of outlet ports, across the width of the proximity head. |
US08317964B2 |
Method of manufacturing a vehicle
A method of manufacturing a vehicle. A set of vehicle body structure components is assembled with interlocking mating features. |
US08317958B2 |
Method for producing single- or multi-layered fiber preforms by the TFP process
A method for producing single- or multi-layered fiber preforms by the TFP process with fiber strands, aligned substantially to be oriented with the flux of force, laid on a backing layer and attached by fixing threads, to form a fiber preform with a desired material thickness and without a backing layer. A release layer is applied at least in certain regions to the backing layer and, after completion of the TFP process, the fiber preform is introduced into a fixing device, in which at least some of the fixing threads are melted. Subsequently the backing layer, separated from the fiber preform by the release layer, is detached from the fiber preform. The fiber preforms have a virtually optimum fiber structure without flaws along with a desired material thickness and are predestined for the production of composite components for load-bearing components that must withstand high mechanical loads. |
US08317953B2 |
Family of metastable intermolecular composites utilizing energetic liquid oxidizers with nanoparticle fuels in sol-gel polymer network
A new process for forming MICs as well as three exemplary categories of MIC formulations is disclosed. MICs disclosed herein include a first exemplary category for which combustion can be initiated and sustained by either a heat (flame) source or electrical power, a second exemplary category of formulations that can be ignited and that sustain combustion at low pressures only with electrical power and a third exemplary category of formulations that can be ignited and extinguished at low pressures only with electrical power. The new process of MIC formulation provides energetic liquid oxidizers in place of traditional solvents, thus eliminating the need for solvent extraction. The energetic liquid oxidizer serves as a medium in which to suspend and grow the 3D nanostructure formed by the cross linked polymer (PVA). As a consequence, the 3D nanostructure entraps the liquid oxidizer, preventing it from evaporating and thereby eliminating the need for solvent extraction, preserves the 3D nanostructure shape. Further, the liquid oxidizer matrix produces provides a mechanism through which ignition and combustion may be controlled. The material combustion rate may be adjusted/throttled through adjustments in the amount electrical power supply and may even be extinguished by complete removal of the electrical power supply. Repeated on/off ignition/extinguishment is possible through repeated application and removal of electrical current. |
US08317946B2 |
Seamless steel pipe and method for manufacturing the same
A seamless steel pipe of a low-alloy steel consisting, by mass %, of C: 0.10 to 0.20%, Si: 0.05 to 1.0%, Mn: 0.05 to 1.2%, Ni: 0.02 to 1.5%, Cr: 0.50 to 1.50%, Mo: 0.50 to 1.50%, Nb: 0.002 to 0.10%, Al: 0.005 to 0.10%, and either or both of Ti: 0.003 to 0.050% and V: 0.01 to 0.20%, the balance being Fe and impurities, the impurities containing 0.025% or less of P, 0.005% or less of S, 0.007% or less of N, and less than 0.0003% of B, wherein the tensile strength is 950 MPa or more and the yield strength is 850 MPa or more, and the Charpy absorbed energy at −40° C. is 60 J or more. This seamless steel pipe may further contain one or more of Cu: 0.02 to 1.0%, Ca: 0.0005 to 0.0050%, and Mg: 0.0005 to 0.0050%. The present invention also provides a method for manufacturing the above-described seamless steel pipe. |
US08317940B2 |
Erosion resistant cermet linings for oil and gas exploration, refining and petrochemical processing applications
The present invention is directed to a method for protecting metal surfaces in oil & gas exploration and production, refinery and petrochemical process applications subject to solid particulate erosion at temperatures of up to 1000° C. The method includes the step of providing the metal surfaces in such applications with a hot erosion resistant cermet lining or insert, wherein the cermet lining or insert includes a) about 30 to about 95 vol % of a ceramic phase, and b) a metal binder phase, wherein the cermet lining or insert has a HEAT erosion resistance index of at least 5.0 and a K1C fracture toughness of at least 7.0 MPa-m1/2. The metal surfaces may also be provided with a hot erosion resistant cermet coating having a HEAT erosion resistance index of at least 5.0. |
US08317936B2 |
Steam dish washer
A dish washer which includes a steam generator. The dish washer, for example, may comprise a tub to provide a room for dishes for washing, a sump to hold water for supplying to the tub for the washing; a steam generator to generate steam, a first tube (or a steam tube) to provide a passage for the steam from the steam generator to the tub, and a valve to release the steam or water from the steam generator according to a pressure. |
US08317935B2 |
Dishwasher apparatus including sound absorbing device
A dishwasher apparatus includes a cover member and a sound absorbing device. The sound absorbing device comprises a sound absorbing element attached to the cover member and a motor guard attached to the sound absorbing element. A portion of the motor guard is positioned between a portion of the motor and a portion of the sound absorbing element. |
US08317933B2 |
Automatic coin-operated or electronic card-operated washing machine and dryer for helmets
An automatic coin—or electronic card—operated washing machine and dryer for helmets, which operates as an automatic and autonomous vending service machine and combines the quick and effective washing of a helmet with the protection of its parts and units and comprises a body (1), where the washing chamber (2) is located. The washing chamber (2), where all cleaning operations of the helmet take place, is supplied with a waterproof gate (17) which is connected thereto. The washing chamber (2) is connected to the brush and spraying mechanism, the wring mechanism (11) and the drying mechanism. The invented washing machine is connected to the water supply through a pipe (4), a water discharge pipe (3) the operation thereof is electronically controlled by an operation control system (14) which is connected to a main server (via a modem). |
US08317929B2 |
Lithographic apparatus comprising an electrical discharge generator and method for cleaning an element of a lithographic apparatus
A method for cleaning elements of a lithographic apparatus, for example optical elements such as a collector mirror, includes providing a gas containing nitrogen; generating nitrogen radicals from at least part of the gas, thereby forming a radical containing gas; and providing at least part of the radical containing gas to the one or more elements of the apparatus. A lithographic apparatus includes a source and an optical element, and an electrical discharge generator arranged to generate a radio frequency discharge. |
US08317928B1 |
Lignin production from lignocellulosic biomass
Methods are disclosed for providing lignin product of a small particle size for improving burning efficiency and for avoiding typical equipment fouling problems while maximizing energy recovery. |
US08317927B2 |
Systems and methods for sealing in site-isolated reactors
Substrate processing systems and methods are described for site-isolated processing of substrates. The processing systems include numerous site-isolated reactors (SIRs). The processing systems include a reactor block having a cell array that includes numerous SIRs. A sleeve is coupled to an interior of each of the SIRs. The sleeve includes a compliance device configured to dynamically control a vertical position of the sleeve in the SIR. A sealing system is configured to provide a seal between a region of a substrate and the interior of each of the SIRs. The processing system can include numerous modules that comprise one or more site-isolated reactors (SIRs) configured for one or more of molecular self-assembly and combinatorial processing of substrates. |
US08317924B2 |
Gas treatment apparatus, gas treatment method, and storage medium
Disclosed is a gas treatment apparatus which can reduce the useless liquid quantity without using an expensive device, such as the evaporator or the mass flowmeter. The control mechanism performs control for exhausting the raw material storage container to make the raw material storage container have a predetermined vacuum pressure, stopping exhaustion to make the raw material storage container be in a sealed state, making the inside of the raw material storage container have the treatment gas atmosphere formed by gasifying the liquid raw material by the vacuum pressure within the raw material storage container, exhausting the chamber to make the chamber have a predetermined vacuum pressure in a state where the target substrate is received in the chamber, stopping the exhaustion to make the inside of the chamber be in a sealed state, opening the opening/closing valve to introduce the treatment gas from the raw material storage container to the chamber, and closing the opening/closing valve when the inside pressure of the chamber reaches a treatment pressure that is higher than the vacuum pressure and lower than a vapor pressure of the liquid raw material to make the chamber have the treatment gas atmosphere of the treatment pressure. |
US08317922B2 |
Gas injection unit and thin film deposition apparatus having the same
A gas injection unit and a thin film deposition apparatus having the gas injection unit are provided. Since a variety of different kinds of organic materials can be sequentially vaporized and injected by a single injection unit, a variety of different kinds of thin films can be deposited in a single chamber. Furthermore, the gas injection structure of the injector unit can be easily controlled. Therefore, even when the process conditions such as the size of the substrate, the process temperature of the chamber, and the like are altered, it becomes possible to actively response to the altered process conditions by simply replacing some parts without replacing the whole injector unit. |
US08317920B2 |
Directional solidification furnace for reducing melt contamination and reducing wafer contamination
A directional solidification furnace includes a crucible for holding molten silicon and a lid covering the crucible and forming an enclosure over the molten silicon. The crucible also includes an inlet in the lid for introducing inert gas above the molten silicon to inhibit contamination of the molten silicon. |
US08317919B2 |
System for continuous growing of monocrystalline silicon
An improved system based on the Czochralski process for continuous growth of a single crystal ingot comprises a low aspect ratio, large diameter, and substantially flat crucible, including an optional weir surrounding the crystal. The low aspect ratio crucible substantially eliminates convection currents and reduces oxygen content in a finished single crystal silicon ingot. A separate level controlled silicon pre-melting chamber provides a continuous source of molten silicon to the growth crucible advantageously eliminating the need for vertical travel and a crucible raising system during the crystal pulling process. A plurality of heaters beneath the crucible establish corresponding thermal zones across the melt. Thermal output of the heaters is individually controlled for providing an optimal thermal distribution across the melt and at the crystal/melt interface for improved crystal growth. Multiple crystal pulling chambers are provided for continuous processing and high throughput. |
US08317916B1 |
Set retardant for hydraulic cement compositions
A zinc-oxide based set retardant additive and admixture for use in Portland cement or other hydraulic cement mixtures. The admixture may comprise silica fume, vitreous calcium aluminosilicate, magnesium aluminum silicate hydrate, a cellulose ether derivative, or their equivalents. The zinc-oxide based set retardant may be interground or pre-blended, pre-packaged, or added on the jobsite, as an admixture, additive, or addition. The zinc-based set retardant may be subsequently added or mixed into a ready mix or wet mixture of portland cement or other hydraulic cement, sand and/or aggregate, with or without fillers, and water, with or without other pozzolans or polymers. |
US08317910B2 |
Immersion platinum plating solution
A platinum plating solution for immersion plating a continuous film of platinum on a metal structure. The immersion platinum plating solution is free of a reducing agent. The plating process does not require electricity (e.g., electrical current) and does not require electrodes (e.g., anode and/or cathode). The solution includes a platinum source and a complexing agent including Oxalic Acid. The solution enables immersion plating of platinum onto a metal surface, a metal substrate, or a structure of which at least a portion is a metal. The resulting platinum plating comprises a continuous thin film layer of platinum having a thickness not exceeding 300 Å. The solution can be used for plating articles including but not limited to jewelry, medical devices, electronic structures, microelectronics structures, MEMS structures, nano-sized or smaller structures, structures used for chemical and/or catalytic reactions (e.g., catalytic converters), and irregularly shaped metal surfaces. |
US08317907B2 |
Water vapor transfer assembly
A water vapor transfer assembly for a fuel cell system includes at least one water vapor transfer device. The water vapor transfer device permits a transfer of water from a wet stream to a dry stream. The water vapor transfer device is disposed between a pair of end plates. The end plates each have a plurality of outwardly extending ribs. The water vapor transfer device and the end plates are disposed within a housing having a pair of wet stream apertures and a pair of dry stream apertures formed therein. The housing further includes a plurality of channels formed adjacent the dry stream apertures. The channels are in fluid communication with the wet stream apertures. The outwardly extending ribs of the end plates cooperate with the channels to define a tortuous bypass flow path between the wet stream apertures of the housing. |
US08317903B2 |
Treatment of contaminated gases
A contaminant is removed from a gas in a method in which the gas is contacted with a solvent for the contaminant, and the resultant solution is contacted with intercalated graphite onto which the contaminant is adsorbed. The solvent will normally comprise water, and may itself be a contaminated liquid. In a preferred method the solvent is in a reservoir with particulate intercalated graphite; the contaminated gas is delivered to the base of the reservoir; and the gas rises in the solvent mobilizing the intercalated graphite in the reservoir. |
US08317897B2 |
Method for supersonically injecting oxygen into a furnace
The invention relates to a method and device for supersonically injecting oxygen into a furnace, in particular a cupola furnace, in which the total oxygen required for the furnace operation is injected with the aid of two distinct circuits, i.e., the first circuit comprising at least one supersonic oxygen injecting nozzle and a second circuit which comprises additionally oxygen injecting means and is connected to the first circuit by pressure-sensitive means, such as a discharging device (or upstream pressure adjuster), in such a way that a stable pressure is obtained in the first circuit upon the attainment of the maximum flowrate thereof, wherein the first circuit can consists of several supersonic nozzle groups. |
US08317890B2 |
Filter assembly; components therefor; and, methods
Air filter assemblies and components therefor are described. The air filter assembly typically includes an air filter cartridge. Air filter cartridges including a media pack comprising at least a first stack of single facer strips are described. In examples described, at least a portion of the first stack of single facer strips is arcuate. Air filter assemblies are characterized that are configured, for example, to advantageously use such air filter cartridges. Example air filter assemblies are described that include pulse jet air cleaning systems. |
US08317889B2 |
Installation structure for dustproof net
Disclosed is an installation structure for a dustproof net to be arranged in a machine, which has an engine, a cooling fan for producing cooling air to cool the engine, plural heat exchangers arranged on an upstream side of the cooling fan, and a compartment with the engine, cooling fan and plural heat exchangers accommodated therein, such that the dustproof net is arranged at a position on a side upstream of the heat exchanger located most upstream among the plural heat exchanger relative to a flow of air drawn in by the cooling fan and in isolation from the most upstream heat exchanger to remove dust contained in the air drawn in by the cooling fan. The dustproof net is provided with a support structure for supporting the dustproof net on members that form the compartment. |
US08317887B2 |
Mixture to add odour to an odourless combustible gas
Mixture to be employed specifically as an agent for adding an odour to a gaseous combustible fuel such as natural gas, consisting of: at least one alkyl acrylate (I) of which the alkyl radicals contain from one to 12 carbon atoms; at least on compound of formula (II) in a quantity sufficient to inhibit the polymerization of the alkyl acrylate or acrylates(I) in the presence and/or absence of oxygen. |
US08317885B2 |
Apparatus for gasifying fuel with a dripper edge and heat shield
The invention provides an apparatus for gasifying a fuel to form synthesis gas wherein also a slag is formed. The apparatus comprises: a pressure shell; a slag bath; a gasifier wall; a free-fall trajectory for slag; and a heat shield. The gasifier wall is arranged inside the pressure shell defining a gasification chamber. It comprises a converging wall part that is provided with a slag discharge opening, located above the quench fluid in the slag bath. The heat shield is arranged above the slag bath between the free-fall trajectory and the pressure shell. The heat shield has a wall structure for allowing passage of a cooling fluid, the wall structure comprising an upper wall part and a lower wall part. The lower wall part of the heat shield is essentially refractory free. |
US08317883B1 |
Production of stable pyrolysis bio-oil from mustard family seeds, mustard family seed presscake, and defatted mustard family seed presscake
Bio-oil from a feedstock selected from mustard family seeds, mustard family seed presscake, mustard family seed defatted presscake, and mixtures thereof. The bio-oil is produced by a method involving (1) pyrolyzing the feedstock to produce bio-oil, bio-char and non-condensable gases, (2) removing the bio-char from the bio-oil, (3) condensing the bio-oil, and (4) precipitating the bio-oil. |
US08317882B2 |
Method of manufacturing a planar electrode with large surface area
A method for fabricating a pair of large surface area planar electrodes. The method includes forming a first template above a first substrate, the first template having a first plurality of pores, coating the first plurality of pores of the first template with a first layer of conducting material to form a first electrode, placing the first plurality of pores of the first electrode in proximity to a second electrode, thereby forming a gap between the first plurality of pores and the second electrode, and filling the gap with an electrolyte material. |
US08317881B2 |
Composition and method for levelling hair colour
The present invention relates to a composition and a method of levelling hair color especially lighter colored hair or including lightened streaks or bleached streaks or bleached as a whole and after certain period of time contrast—difference in color—between the re-growth and formerly lightened parts is clearly visible. The first objective of the present invention is an aqueous composition for levelling hair color comprising at least one fatty acid salt, preferably an in-situ formed ammonium salt, and one or more amphoteric surfactants at a total concentration between 5 and 30% by weight, calculated to total of the composition, and has a pH between 5 and 12. Further the use of the composition for levelling hair color and the method of levelling hair color are disclosed. |
US08317880B2 |
Composition and method for levelling hair colour
The present invention relates to a composition and a method of levelling hair color, especially lighter colored hair or including lightened streaks or bleached streaks or bleached as a whole and after certain period of time contrast—difference in color—between the re-growth and formerly lightened parts is clearly visible. The first objective of the present invention is an aqueous composition for levelling hair color comprising at least one fatty acid salt, preferably an in-situ formed ammonium salt, and one or more anionic surfactants at a total concentration between 5 and 30% by weight, calculated to total of the composition, and has a pH between 5 and 12. Furthermore, use of the composition for levelling hair color and a method of levelling hair color are disclosed. |
US08317879B2 |
Reduced smoking textile care detergents
The present invention provides compositions and methods to reduce smoking and/or haze during a heated laundry process. The compositions include a smoke reducing surfactant package and a detersive surfactant containing an amount of free alcohol. The smoke reducing surfactant package includes an anionic surfactant, an amphoteric surfactant or mixtures thereof. The surfactants are selected such that the amount of smoke or haze produced is reduced and or eliminated when garments contacted with the compositions containing the surfactants are heated to at least about 250° F. Methods of using the compositions are also provided. |
US08317876B2 |
Artificial foot
The invention relates to an artificial foot with a connecting part for a lower leg part, a forefoot part which is pivotably connected to the connecting part by means of an upper coupling element and a lower coupling element in such a way that an angular position of the connecting part controls an angular position of the forefoot part, one of the coupling elements extending into a heel area of the foot. |
US08317874B2 |
Orthopedic fluid damper and method
The invention relates to an orthopaedic aid, in particular to a prosthesis (58) or orthosis comprising an orthopaedic fluid damper (10) with a displacement chamber (14) formed in a housing (12), with a piston (16) mounted in the displacement chamber (14), with a fluid reservoir for a fluid (20), with a return flow conduit (22) connecting the displacement chamber (14) to the fluid reservoir, with a valve (24) that can adopt an open position and a closed position, in which it at least partially closes the return flow conduit (22), and with a joint (72) that has a first branch (60) and a second branch (66), wherein the first branch (60) is connected to the housing (12) and the second branch (66) is connected to the piston (16). A device (84) is also provided for detecting a joint force (FB) acting on the joint, which device (84) is designed to bring the valve (24) to the closed position when the joint force (FB) exceeds a predefined threshold value. The invention also relates to a method for control of the aid and a fluid damper (10) fitted therein. |
US08317871B2 |
Modular humeral head resurfacing system
A two piece humeral component for use in joint arthroplasty which is adapted to be implanted into a joint and engaged by a socket component of the joint. The joint component includes a body having a first articulating surface and a second medial surface opposite the first articulating surface. The first articulating surface is adapted to be engaged by the socket and the second medial surface is adapted to be secured to mounting portion. The mounting portion has a first surface and a second medial surface. The first surface is adapted to be fixably engaged to the second mounting portion of the humeral component. The second medial surface is adapted to be secured to the humerus. A peg which has a first end adapted to engage a cavity found in the humerus is disposed on the mounting portion's second medial surface. |
US08317864B2 |
Systems and methods for posterior dynamic stabilization of the spine
Devices, systems and methods for dynamically stabilizing the spine are provided. The devices include an expandable spacer or member having an unexpanded configuration and an expanded configuration, wherein the expandable member in an expanded configuration has a size, volume and/or shape configured for positioning between the spinous processes of adjacent vertebrae in order to distract the vertebrae relative to each other. The systems include one or more expandable members and a mechanical actuation means for expanding the expandable member. The methods involve the implantation of one or more devices or expandable spacers. |
US08317863B2 |
Flexible tibial sheath
A radially expandable sheath is provided having a substantially closed distal end with at least two sidewalls extending proximally therefrom and defining a central lumen. Each sidewall can have a substantially concave outer surface adapted to seat a graft member, and each side wall is at least partially separated by a longitudinally oriented slot that extends from a proximal end along a substantial length of each sidewall. The slot preferably terminates at a position just proximal to the distal end. The device can also include a sheath expander that is adapted to be disposed in the central lumen of the radially expandable sheath and that is configured to flex the sidewalls to radially expand the sheath so as to fix a graft member within a bone tunnel. |
US08317862B2 |
Method for replacing a ligament in a knee
A method of providing a replacement anterior cruciate ligament (ACL) provides a tibial tunnel and at least one femoral tunnel for receiving the replacement ligament, the femoral and tibial tunnels not being colinear but rather in an orientation that more closely mimics the natural ACL. The femoral tunnel is formed through the anterior medial portal. A cross pinning guide having a femoral rod for insertion into the femoral tunnel, a spaced apart arc shaped track and a guide block having one or more bores aligned with the femoral rod whereby an instrument inserted through one of the bores creates a pilot hole for the cross pin which intersects the femoral tunnel and an appropriate angle thereof which avoids ligaments and other sensitive tissue can be selected by adjusting the guide block along the track. |
US08317861B2 |
Antimicrobial indwelling voice prosthesis
A voice prosthesis comprising a tubular body portion, a valve and a valve seat disposed within the body portion. The valve seat is further comprised of a medical grade elastomer containing a dispersion of an antimicrobial agent. This valve seat extends the life of the prosthesis by retarding the growth of microorganisms. The body portion of the prosthesis may also contain an antimicrobial agent at a concentration that is non-toxic to the tissue it contacts. |
US08317859B2 |
Devices and methods for controlling expandable prostheses during deployment
Prosthesis delivery devices and methods are provided that enable precise control of prosthesis position during deployment. The catheter for delivering a prosthesis to a treatment site in a body lumen typically carries one or more self-expanding tubular prostheses within a sheath. A radially expandable control member is positionable within the prostheses and has an expanded shape which engages an inner surface of the prostheses to urge the prostheses outwardly against the sheath. The radially expandable control member therefore controls axial position of the prostheses during deployment. Thus one or more prostheses may be deployed at a treatment site precisely. When multiple prostheses are deployed, excessive spacing or overlap between adjacent prostheses is minimized. The prostheses of the present invention are often deployed in stenotic lesions in peripheral arteries as well as coronary arteries and other body lumens. |
US08317856B2 |
Multi-component expandable supportive bifurcated endoluminal grafts and methods for using same
A multiple-component expandable endoluminal system for treating a lesion at a bifurcation including a self expandable tubular root member having a side-looking engagement aperture, a self expandable tubular trunk member comprising a substantially blood impervious polymeric liner secured therealong; both having a radially compressed state adapted for percutaneous intraluminal delivery and a radially expanded state adapted for endoluminal support. |
US08317853B2 |
Prosthetic valve with external support frame
Prosthetic valves, methods of making medical devices, and methods of treatment are provided. The prosthetic valves of the invention have a valve portion moveable between first and second positions, and a spacing member that has a thickness and protects a portion of the valve portion from contact with a wall of a vessel in which the prosthetic valve is implanted, and/or another structural component of the prosthetic valve, such as a support frame. |
US08317852B2 |
Stent having helical elements
An expandable stent comprised of a plurality of helical segments is disclosed. In one embodiment, the stent is generally cylindrical in shape having a cylindrical axis, and comprises a first and second set of helical segments. The helical segments in the first set are substantially parallel and have a first pitch forming a first helical angle with respect to the cylindrical axis. The helical segments in the second set are also generally parallel to each other and form a second pitch that differs from the first pitch, thereby forming a second helical angle with respect to the cylindrical axis. In an alternative embodiment, the stent comprises one set of helical segments and a plurality of circumferential elements that are joined together by the helical segments to form a plurality of cylindrical elements which are joined together to form a stent body. The stent may also have endzones. |
US08317851B2 |
Longitudinally flexible stent
An intravascular stent especially suited for implanting in curved arterial portions. The stent retains longitudinal flexibility after expansion. The stent is formed of intertwined meander patterns forming triangular cells. The triangular cells are adapted to provide radial support, and also to provide longitudinal flexibility after expansion. The triangular cells provide increased coverage of a vessel wall. The stent can have different portions adapted to optimize radial support or to optimize longitudinal flexibility. The stent can be adapted to prevent flaring of portions of the stent during insertion. |