| Document | Document Title |
|---|---|
| US08310259B2 |
Silicon carrier space transformer and temporary chip attach burn-in vehicle for high density connections
A silicon carrier space transformer assembly includes one or more silicon structures, which provide space transformer scaling to permit interconnection for fine pitch input/output interconnections with a semiconductor die or wafer, and fine pitch test probe tips connected to the one or more silicon structures. |
| US08310254B2 |
Probe pin
There is provided a material having an excellent conductivity and oxidation resistance as well as a sufficient hardness for probe pins. The present invention provides a probe pin material including Au, Ag, Pd and Cu, wherein the concentration of Au is 40 to 55% by weight, the concentration of Ag is 15 to 30% by weight and the total concentration of Pd and Cu is 15 to 40% by weight. This material can further include 0.6 to 5% by weight of any one element from among Ni, Zn and Co. Furthermore, this alloy can be precipitation-hardened by being heated at 300 to 500° C., enabling provision of a material having a higher hardness. |
| US08310253B1 |
Hybrid probe card
A hybrid probe card and methods are provided. A plurality of uniform sized probe pins are provided in a probe card for performing wafer probe testing. The probe card also includes at least one enlarged probe pin having a current carrying capacity that is at least 25% greater than the current carrying capacity of the uniform sized probe pins. The enlarged probe pins are provided, e.g., to prevent damage to the probe pins caused by large current flow. Methods for identifying the probe pin locations where the enlarged probe pins should be deployed are described. |
| US08310247B2 |
Method of determining contact position in electronic apparatus
A method of determining a contact position in an electronic apparatus including capacitance sensing circuits that output capacitance measuring signals and light sensing circuits that output light measuring signals includes acquiring the capacitance measuring signals by sequentially scanning the capacitance sensing circuits, determining whether a target object is in contact with a contact surface based on the acquired capacitance measuring signals, acquiring the light measuring signals by sequentially scanning the light sensing circuits after the target object is determined to be in contact with the contact surface, and determining a position of the contact surface, with which the target object is in contact, based on the acquired light measuring signals. The acquiring of the capacitance measuring signals and the determining of whether the target object is in contact with the contact surface are repeated until the target object is determined to be in contact with the contact surface. |
| US08310246B2 |
Continuity testing apparatus and continuity testing method including open/short detection circuit
A continuity testing apparatus includes open/short detection circuits provided for to-be-tested terminals, respectively and configured to determine the presence or absence of at least any one of an open-circuit failure and a short-circuit failure in to-be-tested terminals. Then, the continuity testing apparatus generates detected results of the open/short detection circuits based on the condition of continuity of the to-be-tested terminals having connections to the open/short detection circuits and the detected results from the open/short detection circuits in the preceding stages, and outputs the generated detected results to the open/short detection circuits in the succeeding stages. Further, the continuity testing apparatus determines the condition of continuity based on the output from the open/short detection circuit in the last stage. |
| US08310245B2 |
Modelling a power production network for distributing the load
The modelling arrangement of the configuration situation of the electric power transmission network according to the invention comprises a modelling element (7) designed to be installed in each generator of the electric power transmission network. The modelling element (7) is arranged to measure the state of the said switches until an open switch is detected and to detect the corresponding generator on the basis of the closed switch and thus to model the power transmission network comprising the detected generators and the area of the power transmission network belonging to the same electric network via closed switches. |
| US08310227B2 |
Electronic measuring wheel
An electronic measuring wheel has a casing, a distance wheel and an operating shaft. The casing has a power supply, a seven-segment display and a sensor. The seven-segment display is mounted in the casing and is electrically connected to the power supply. The sensor is mounted on the seven-segment display in the casing and is electrically connected to the power supply and the seven-segment display. The distance wheel is rotatably connected to the casing and has a distance wheel axle and an induction ring. The distance wheel axle has an inner end mounted in the casing. The induction ring is mounted around the inner end of the distance wheel axle near the sensor. The operating shaft is connected to the casing. |
| US08310226B2 |
Diagnosing device of signal status in measurement and control by measuring means and control means
This aims to provide a diagnosing device for detecting the measurements of an electric current, a voltage and a resistance by a temperature/moisture or pressure sensor or a signal state in control means, precisely with a simple circuit constitution, for diagnosing the soundness of a circuit while simplifying a power source circuit, to suppress the cost more than the conventional circuit having no diagnosing function, and for diagnosing the signal status in the measurement or control by a measuring means or a control means. An alternating voltage generating means containing a pulse-wave voltage and an alternating current is connected with the primary side of a transformer, and a driven member such as the measuring means for any of varying electric current, voltage and resistance is connected with the secondary side. The change in the primary-side current, which is caused with the electric power fed through an insulating transformer by the action of the driven member connected with the secondary side, is measured so that the signal status in the measuring or control means is diagnosed according to the measurement result. |
| US08310223B2 |
Electrical probe and associated method
An electrical probe and associated method are provided to establish electrical contact with a wire. The electrical probe includes an elongate member extending between opposed first and second ends, and first and second needles connected to the elongate member and extending beyond the first end of the elongate member. The electrical probe also includes first and second conductors electrically connected to the first and second needles, respectively, and extending along the elongate member. The electrical probe also includes a bumper stop connected to the elongate member proximate the first end of the tube. Further, the electrical probe includes a movable engagement member extending lengthwise along the elongate member. The moveable engagement member includes a hook that extends beyond the first end of the elongate member and beyond the first and second needles. The hook may include a terminal portion configured to contact the bumper stop. |
| US08310219B2 |
DC-DC converter with a PWM mode and a continuously on mode
A DC-DC converter including, an inductor; and a driving switching element for performing switching to a flow path to flow an electric current through the inductor; wherein the DC-DC converter drives the driving switching element by PWM control using a PWM control pulse to convert a direct-current input voltage supplied from a direct-current power source and to output a direct-current voltage having a piece of electric potential different from that of the direct-current input voltage, and wherein the DC-DC converter drives the driving switching element by the PWM control under a first condition, and the DC-DC converter makes the driving switching element be in an on-state continuously while the output direct-current voltage is lower than a desired level under a second condition. |
| US08310218B2 |
Time-multiplexed-capacitor DC/DC converter with multiple outputs
A multiple output DC-to-DC voltage converter using a new time-multiplexed-capacitor converter algorithm and related circuit topologies is herein disclosed. One embodiment of this invention includes a flying capacitor, a first output node, a second output node, and a switching network. The switching network configured to provide the following modes of circuit operation: 1) a first mode where the positive electrode of the flying capacitor is connected to an input voltage and the negative electrode of the flying capacitor is connected to ground; 2) a second mode where the negative electrode of the flying capacitor is connected to the input voltage and the positive electrode of the flying capacitor is connected to the first output node; and 3) a third mode where the positive electrode of the flying capacitor is connected to ground and the negative electrode of the flying capacitor is connected to the second output node. |
| US08310213B2 |
Electrical component fault detection
A motive unit, such as a generator, is disclosed. The motive unit has a fault transmitter to provide a status indication of a component of the motive unit. Failure of a component, such as a diode on the rotor of a generator, can be accordingly communicated. |
| US08310208B2 |
Charging algorithm for lithium batteries
A method of developing an optimum a lithium battery charging algorithm is conducted by providing a salt dissolved in solvent permitting lithium ions to leave a cathode in large format battery cells. Charge and discharge are then measured under different C-rate conditions. Using the cathode material phase transformations to ascertain a differential curve, peaks in the differential curve are observed with all data plotted against dV/dt and V, where V represents voltage and t represents time. Areas in voltage ranges are then observed where the rate of increase is higher than in other areas. By varying the charging current, an optimum charging voltage can be ascertained and maintained. |
| US08310206B2 |
Monitoring battery cell voltage
An apparatus includes battery gauge circuitry implemented on an integrated circuit. The battery gauge circuitry includes a plurality of switches that individually open in response to a voltage reduction on a battery cell associated with a respective one of the switches. The battery gauge circuitry also includes a logic device that determines if at least one of the switches is open. The battery gauge circuitry also includes a register that stores data that indicates if at least one switch is open. The battery gauge circuitry also includes a controller that initiates halting power delivery to a load if at least one of the switches is open. The controller also identifies the open switch. |
| US08310202B2 |
Off-resonance frequency operation for power transfer in a loosely coupled air core transformer
A power transmission system includes a loosely coupled air core transformer having a resonance frequency determined by a product of inductance and capacitance of a primary circuit including a primary coil. A secondary circuit is configured to have a substantially same product of inductance and capacitance. A back EMF generating device (e.g., a battery), which generates a back EMF with power transfer, is attached to the secondary circuit. Once the load power of the back EMF generating device exceeds a certain threshold level, which depends on the system parameters, the power transfer can be achieved at higher transfer efficiency if performed at an operating frequency less than the resonance frequency, which can be from 50% to 95% of the resonance frequency. |
| US08310197B2 |
Control device for electric motor drive device
A control device that includes an AC voltage command determination section that determines an AC voltage command value, which is a command value of the AC voltage supplied from the DC/AC conversion section to the AC electric motor, on the basis of a target torque of the AC electric motor and a rotational speed of the AC electric motor; and a system voltage command determination section that determines a system voltage command value, which is a command value of the system voltage generated by the voltage conversion section, on the basis of the AC voltage command value and the system voltage. |
| US08310196B2 |
Method and apparatus for failsafe monitoring an electromotive drive
A method and an apparatus for the failsafe monitoring of an electromotive drive without additional sensors, including a drive having a three-phase control of an electric motor, detection of the current and voltage profiles of each of the three phases, as they are forwarded to the motor by drive electronics, determination of the load speed while using the detected current and voltage values, where the determination of the load speed takes place by calculating an observer model with reference to the detected current, to the detected voltage, to the frequency preset by the control and to the characteristic data of the motor and generation of a failsafe switch signal for the motor when the calculated load speed does not correspond to a preset desired speed within the framework of preset tolerances. The load torque can also be determined and monitored with reference to the observer model. |
| US08310194B2 |
Load drive device and control system of the same
A load drive device for driving an inductive load by PWM controlling a switching element includes synchronization control unit, a synchronization signal input terminal, and a synchronization signal output terminal. The synchronization control unit outputs the PWM signal to the switching element. The synchronization control unit receives a synchronization signal through the input terminal from an exterior. The synchronization control unit outputs the synchronization signal through the output terminal to an exterior. When the synchronization control unit does not receive the synchronization signal, the synchronization control unit outputs the synchronization signal such that a first switching period of the PWM signal is prevented from overlapping with a second switching period of a PWM signal of an external device. When the synchronization control unit receives the synchronization signal, the synchronization control unit generates the PWM signal based on the synchronization signal. |
| US08310186B2 |
Apparatus for carrying out improved control of rotary machine
In an apparatus, a predicting unit predicts, based on a target value of a drive mode of a power converter at a next timing, a first value of a controlled variable. The drive mode is indicative of a switching-state of each of a plurality of switching elements. The target value of the drive mode of the power converter at the next timing is temporarily set at a present timing prior to the next timing. A driving unit drives the plurality of switching elements based on the target value of the drive mode at the next timing while limiting a number of switching-state changes in the plurality of switching elements from the present timing to the next timing as long as the deviation between the predicted first value of the controlled variable at the further next timing and a command value therefor is within a threshold range. |
| US08310184B2 |
PWM control circuit and PWN control method
The PWM control circuit includes a polarity determination unit, a full wave rectification unit, an adjustment unit that generates an adjusted waveform signal by adjusting waveform of the full wave rectification signal, and a carrier signal generating unit that generates a fixed frequency carrier signal. The PWM control circuit further includes a comparator that generates an original PWM signal by comparing the adjusted waveform signal and the carrier signal, and a PWM waveform shaping unit that generates a first PWM signal for the positive polarity section and a second PWM signal for the negative polarity section, by shaping the original PWM signal according to the polarity signal. |
| US08310181B2 |
Motor drive system using potential at neutral point
According to input parameters, a controller carries out: generation of a voltage command value for each of d- and q-axes; conversion of the voltage command value for each of the d- and q-axes into a voltage command value for each of the multiphase windings; and control of a multiphase inverter based on the voltage command value for each of the multiphase windings. The controller adds, to the voltage command value for the q-axis, a first compensation voltage value for compensating torque ripples to thereby output a compensated voltage command value for the q-axis. The first compensation voltage value contains m-th harmonic components in the AC motor and varies depending on the rotational angle of the rotor, the m corresponding to the number of phase of the multiphase windings. The controller uses, as the voltage command value for the q-axis, the compensated voltage command value for the q-axis. |
| US08310179B2 |
Patient-lifting-device controls
Systems, methods and apparatus are provided through which in some multisensory implementations, a patient-lifting-device is controlled by voice recognition using a background noise filter, keyboard text input, synaptic control and/or a tongue tactile input commands. In some implementations, the command is rejected or accepted in reference to an analysis of the command, the analysis including an analysis of the authority of operator, competency and/or the state of mind of the operator. |
| US08310171B2 |
Line voltage dimmable constant current LED driver
A programmable LED constant current driver circuit for driving LEDs at constant current and dimming the LEDs using standard, off-the-shelf dimmers is provided. The current driver circuit of the present disclosure includes a temperature compensation feature which controls the on time for the LEDs based on a measured temperature of the current driver and associated circuits. In another embodiment, the current driver circuit is designed to receive a 24 VAC input and drive one or more LEDs in a transformer-based system dimming system. |
| US08310167B2 |
Arrangement for controlling light emitting diodes
In a circuit arrangement for controlling light emitting diodes (LEDs), which are combined in an indicating table, including a voltage supply, at least one driver which is connected to the voltage supply and has current outputs by way of which current can be supplied to the LEDs as well as at least one control input via which the current being supplied to the LEDs is controllable, a control element is provided by which the number of the LEDs to which current has to be supplied at the same time can be determined and a signal indicative of the number determined can be supplied to the control input of the driver for assisting in controlling the power supply to the LEDs. |
| US08310166B2 |
Lighting device and lighting fixture using the same
A lighting device receives an output of a power supply phase detector and performs a lighting control of a lighting load by a trigger signal to be output from a load controller to a switching element (a load drive unit) at an arbitrary conduction angle. The load controller includes a determination unit that turns on the switching element at a phase of a conduction angle of a commercial power supply in which any lighting load (an incandescent lamp, a bulb-type fluorescent lamp, and an LED lamp) can be turned on during a predetermined period after turning on a power supply, so as to determine a type of the lighting load during the period. The load controller switches to a predetermined operation mode depending on a type of the lighting load determined by the determination unit. |
| US08310163B2 |
Microcontroller-based lighting control system and method for lighting control
A lighting control system employs a microcontroller to generate time-delay pulses that are synchronized with the AC power. The time-delay pulses control conduction period of a semi-conductor switching device for transmitting AC power to a lighting load. This lighting control system enables the lighting load performing two-level or multi-level illumination in a simple and power saving manner. While the conventional circuits use cumbersome passive resistor-capacitor scheme to generate required timing control, this lighting control system uses simple scheme based on a built-in oscillator in the microcontroller. This scheme provides high flexibility and accuracy to implement delay-time triggering. The system and method in the present invention may simultaneously be applicable to lighting loads of different impedance types, especially to incandescent lamp, fluorescent lamp, and AC light emitting diode. |
| US08310160B1 |
Anti-arcing circuit for current-fed parallel resonant inverter
An arc protection circuit is provided for a current-fed, parallel-resonant inverter ballast, the circuit having a lamp signal sensing circuit coupled across one or more lamps and designed to detect a signal through the lamps, a shutdown circuit coupled to the sensing circuit and operable to disable the ballast in response to a disturbance such as an arc in the detected signal, at least a portion of the shutdown circuit defining a first time delay from detection of the disturbance in the signal during which the ballast operates normally, and after which the ballast may be disabled in response to the disturbance; and an automatic restart circuit coupled to the shutdown circuit and operable to enable restarting of the ballast, at least a portion of the restart circuit defining a second time delay during which the ballast remains disabled, after which the ballast may be restarted. |
| US08310157B2 |
Lamp having metal conductor bonded to ceramic leg member
A lamp includes a discharge vessel comprising a body portion defining a discharge space and leg members extending therefrom. Electrode assemblies include conductors carried by bores of the respective leg members. At least one of the conductors is bonded directly to the respective leg member within the bore, without the need for a sealing material, to form an airtight seal. Electrodes are electrically connected to the conductors and extend into the discharge vessel. An ionizable fill is sealed within the vessel. |
| US08310145B2 |
Light emitting device including first and second red phosphors and a green phosphor
A light emitting device according to one embodiment includes a light emitting element that emits light having a wavelength of 380 nm to 470 nm; a CASN first red phosphor that is disposed on the light emitting element; a sialon second red phosphor that is disposed on the light emitting element; and a sialon green phosphor that is disposed on the light emitting element. |
| US08310143B2 |
Lighting device and lighting method
A lighting device comprising at least one solid state light emitter and at least one lumiphor. If each solid state light emitter is illuminated and each lumiphor is excited, a mixture of light emitted has x, y color coordinates within an area defined by the coordinates 0.32, 0.40; 0.36, 0,48; 0.43, 0.45; 0.42, 0.42; and 0.36, 0.38. The lumiphor(s) comprises phosphor particles, in the range of from 3 to 7 micrometers (or 5-15, 10-20, or 15-25 micrometers), or having a mean particle size of 5, 10, 15, 20 micrometers. Also, a lighting device comprising at least one emitter and at least one lumiphor in which the lumiphor comprises phosphor particles having sizes as mentioned above, where the lighting device has an efficacy of at least 60 (or 70, or 80) lumens per watt. |
| US08310139B2 |
LED lamps using recycled metal containers as heat sinks
The core of this invention is that using recycled metal cans (after pretreatment processes) as a good heat sink, the lamp cups, of the LED lamps to adhere to the lamp bases, circuit boards with LED and lamp cups through advanced technology, there by producing a variety of LED lamps. And finally, this invention achieves a complete metal construction of LED lamps which not only improves the thermal performance of LED lamps but also develops a low-carbon, environmentally friendly and economical way of metal containers recycling consequently makes this LED lamps suitable to be widely used for the purpose of illumination or decoration. |
| US08310134B2 |
Composition for energy generator, storage, and strain sensor and methods of use thereof
Compositions and devices for harvesting electrical energy from mechanical and thermal energy, storing such produced energy, and sensing strain based on low cost materials and processes. In embodiments, the compositions are flexible and include a flexible polymer embedded and coated with a nanostructured piezoelectric material. |
| US08310122B2 |
Core plate stack assembly for permanent magnet rotor or rotating machines
A rotating machine has a stator and a permanent magnet rotor that is more easily made, lower cost, and lighter by virtue of a plurality of permanent magnet assemblies mounted on a rotor body. Each magnet assembly includes two facing core plate stacks supporting a permanent magnet between them. Each core plate stack is made from a plurality of core plates of substantially identical size and shape and with on or more holes in substantially the same location to form respective bores in the stack. A tie rod is formed in each bore and retains the plates in a stack via bevels in the holes of the end plates. Preferably, the tie rods also apply compressive force as a result of placing the stacked plates in an injection mold, injecting plastic into the mold to fill each bore with plastic, and allowing the plastic to cure. As the plastic cures, it shrinks so that the tie rods pull the end plates together. To enhance the pressure, the stacked plates can be compressed before and during the injection process. |
| US08310121B2 |
Electronic circuit-integrated motor drive and semiconductor module
A motor case is formed in a tubular shape. A semiconductor module includes a semiconductor chip of switching elements, a resin part and a coil terminal. The resin part embeds the semiconductor chip therein. The coil terminal is protruded from the resin part and directly connected to a coil. A connection part between the coil terminal and the coil is arranged at a position, which is between a top wall surface and a bottom wall surface of the resin part facing each other in the axial direction of a motor. |
| US08310119B2 |
Electric motor
A shaft is adapted to be inserted through a circuit apparatus without a need for disassembling a shaft side sensor device from an end part of the shaft to place the shaft side sensor device in an opposed relationship to a circuit board side sensor device at a location adjacent to the circuit board side sensor device. The shaft side sensor device forms a sensor apparatus in cooperation with the circuit board side sensor device to sense a rotational angle of the rotor. |
| US08310115B2 |
High power-density, high efficiency, non-permanent magnet electric machine
A system and method of manufacturing an electric machine comprising a rotor and a stator, wherein the stator comprises a fractional-slot concentrated winding having two sets of terminals, wherein a first set of terminals configures the fractional-slot concentrated winding to have a first pole-number (P1), and wherein a second set of terminals configures the fractional-slot concentrated winding to have a second pole number (P2) different from the first pole-number (P1). |
| US08310114B2 |
Power generating device
A power generating device includes a carrier module, a stator module, a rotor module and a power generating module. The stator module is assembled to the carrier module, and has a first circuit board and a plurality of driving coils. The rotor module is located in an electromagnetic field, and has a multipolar magnetic rotor and a rotating axle. A magnetic field of the multipolar magnetic rotor interacts with the electromagnetic field to make the rotor module rotating relative to the stator module, and make the multipolar magnetic rotor producing a varying magnetic field. The power generating module is located in the varying magnetic field, and has a second circuit board and a plurality of induction coils. The induction coils induct the varying magnetic field to output an induction circuit to the second circuit board. |
| US08310113B2 |
Multiple armature linear motor/alternator having magnetic spring with no fringe fields and increased power output
An electromagnetic, reciprocating linear motor or alternator having at least two armatures that are adjacent along an axis of reciprocation. The armatures have gaps that are linearly aligned along a gap path parallel to the axis. Field magnets reciprocate within the gap path. The field magnets include a main field magnet associated with each armature, each main field magnet having a magnetic polarization in the same direction across the gap path. A secondary magnet provides a centering spring force and is interposed between the main magnets. The secondary magnet extends in an axial direction from within a gap of one armature core to within an adjacent gap of an adjacent armature core. The secondary magnet is magnetically polarized in a direction opposite the polarization of the main magnets. |
| US08310110B2 |
Power switch circuit
A power switch circuit includes first and second power switches, first to fourth inverters, first and second diodes. An input of the first inverter is connected to a first positive terminal of the first power switch. An input of the second inverter is connected to an output of the first inverter. A cathode of the first diode is connected to an output of the second inverter. An anode of the first diode is connected to a power-on terminal of a motherboard. An input of the third inverter is connected to a second positive terminal of the second power switch. An input of the fourth inverter is connected to an output of the third inverter. A cathode of the second diode is connected to an output of the fourth inverter. An anode of the second diode is connected to the power-on terminal. |
| US08310107B2 |
Power transmission control device, power transmitting device, non-contact power transmission system, and secondary coil positioning method
A power transmission control device used for a non-contact power transmission system includes a power-transmitting-side control circuit that controls power transmission to a power receiving device, and a harmonic detection circuit that detects a harmonic signal of a drive frequency of a primary coil. A resonant circuit (leakage inductance and resonant capacitor) that resonates with the harmonic of the drive frequency of the primary coil L1 is formed in the power receiving device so that harmonic resonance occurs. The harmonic detection circuit detects the harmonic resonance peak of the drive frequency of the primary coil. |
| US08310099B2 |
Energy supply in which a plurality of components disposed along a transmission route each transform a voltage
An energy supply is provided along a route with at least one distribution station, wherein a first voltage is applied at the input and a second voltage at the output. The second voltage is lower or higher than the first voltage. A plurality of components are arranged along the route. A component, which is supplied with the second voltage, includes a power supply unit for transforming the second voltage into a third voltage. |
| US08310095B2 |
Power compensator and method for providing a black start with that compensator
A power compensator for an electric power transmission line. The power compensator includes a voltage source converter, a capacitor and an energy storage device. The energy storage device includes a high voltage battery having a short circuit failure mode, a first main switch and second main switch for disconnecting the battery from the capacitor, and a control unit for operating the first and second switch. |
| US08310093B1 |
Multiply-connected power processing
Various power processing systems are described that employ a multiply-connected velocity inhibiting circuit. At least one active circuit is employed to synthesize at least one passive lumped element in the multiply-connected velocity inhibiting circuit. |
| US08310084B2 |
Device and method for controlling a power shunt circuit, hybrid vehicle having same
A device for controlling a power shunt circuit of a hybrid vehicle, including inverters, including DC sides linked to a DC voltage storage unit and AC sides intended to be linked to polyphase electrical machines. The polyphase electrical machines are able to operate in engine/engine or generator/generator modes. A control unit controls chopping switches of the second inverter in a way that is temporally offset relative to chopping switches of the first inverter in such a case, the control unit of the inverters controlling their chopping switches by pulse width vector modulation. |
| US08310083B2 |
Apparatus and system for power conversion
An apparatus includes a DC-link, a voltage converter, a bus voltage controller, and a supervisory controller. The voltage converter is configured to convert a first DC voltage into a second DC voltage based on a command signal and based on an adjustment signal and to supply the second DC voltage to the DC-link. The bus voltage controller is configured to iterate calculation of the adjustment signal to communicate each iterated calculation of the adjustment signal to the voltage converter. The supervisory controller is configured to iterate calculation of the command signal and to communicate each iterated calculation of the command signal to the voltage converter and to the bus voltage controller. A frequency of the bus voltage controller to communicate each iterated calculation of the adjustment signal is higher than a frequency of the supervisory controller to communicate each iterated calculation of the command signal. |
| US08310077B2 |
Tidal electricity generating apparatus
A turbine adapted to be constrained within a flow of fluid includes a stator adapted to be constrained within a flow of fluid, and a rotor defining an aperture and having rotor blades protruding from a peripheral region of the rotor into the aperture. The rotor is adapted to be rotatably mounted to the stator such that movement of fluid through the aperture causes rotation of the rotor relative to the stator. Electricity is generated as a result of rotation of the rotor relative to the stator. |
| US08310075B2 |
Shadow control of wind turbines
A rotor of a wind turbine may cast an intermittent shadow onto an object in the vicinity of the turbine. A shadow-control system stops the wind turbine, based on a shadow-related shut-down condition. The condition is based on a result of a comparison between a direct-light intensity and an indirect-light intensity being beyond a direct-to-indirect light threshold. A set of light sensors measures the direct- and indirect-light intensities. A sensor measures the direct light intensity when irradiated by the sun, and the indirect-light intensity when not irradiated by the sun. The set of light sensors to provide the measured direct- and indirect-light intensities for the comparison consists of two sensors, an eastward-oriented sensor and a westward-oriented sensor. |
| US08310069B2 |
Semiconductor package having marking layer
The symbolization of a semiconductor device (100) is incorporated in a thin sheet (130) attached to the top of the device, facing outwardly with its bare surface. The material of the sheet (about 1 to 10 μm thick) includes regions of a first optical reflectivity and a first color, and regions (133) of a second optical reflectivity and a second color, which differ from, and contrast with, the first reflectivity and color. Preferred choices for the sheet material include the compound o-cresol novolac epoxy and the compound bisphenol-A, more preferably with the chemical imidazole added to the film material. A preferred embodiment of the invention is a packaged device with a semiconductor chip a (101) connected to a substrate (102); the connection is achieved by bonding wires (111) forming an arch with a top 111a. The chip, the wire arches, and the substrate are embedded in an encapsulation material (120), which borders on the attached top sheet so that the arch tops touch the border (131). |
| US08310067B2 |
Ball grid array package enhanced with a thermal and electrical connector
A package is provided. The package includes a substrate having first and second surfaces, a stiffener coupled to the first surface of the substrate, and a thermal connector coupled to the second surface of the substrate that is configured to be coupled to a printed circuit board. |
| US08310066B2 |
Semiconductor apparatus
A semiconductor apparatus capable of detecting a crack generated in a semiconductor chip while the design freedom, the layout freedom of a wiring, the layout efficiency of LSI, and the layout efficiency of a package substrate are improved. The semiconductor apparatus according to the invention includes a semiconductor chip having a multilayered wiring structure; plural electrode pads being formed on a top surface along the outer periphery of the semiconductor chip; and a wiring being coupled to a first electrode pad and a second electrode pad selected from the plural electrode pads and formed along the entire outer periphery of the semiconductor chip in plan view. The wiring includes a first wiring and a second wiring that are formed on different layers, and the first wiring and the second wiring are connected in series by a connection plug. |
| US08310064B2 |
Semiconductor devices including voltage switchable materials for over-voltage protection
Semiconductor devices are provided that employ voltage switchable materials for over-voltage protection. In various implementations, the voltage switchable materials are substituted for conventional die attach adhesives, underfill layers, and encapsulants. While the voltage switchable material normally functions as a dielectric material, during an over-voltage event the voltage switchable material becomes electrically conductive and can conduct electricity to ground. Accordingly, the voltage switchable material is in contact with a path to ground such as a grounded trace on a substrate, or a grounded solder ball in a flip-chip package. |
| US08310060B1 |
Lead frame land grid array
A package includes a first plated area, a second plated area, a die attached to the first plated area, and a bond coupling the die to the second plated area. The package further includes a molding encapsulating the die, the bond, and the top surfaces of the first and second plated areas, such that the bottom surfaces of the first and second plated areas are exposed exterior to the package. Additional embodiments include a method of making the package. |
| US08310056B2 |
Semiconductor device
In a semiconductor device, a lower multi-layered interconnect structure, an intermediate via-level insulating interlayer, and an upper multi-layered interconnect structure are stacked in this order in a region overlapped with a bonding pad in a plan view; upper interconnects and vias of the upper multi-layered interconnect structure are formed so as to be connected to the bonding pad in the pad placement region; the intermediate via-level insulating interlayer has no electro-conductive material layer, which connect the interconnects or vias in the upper multi-layered interconnect structure with interconnects or vias in the lower multi-layered interconnect structure, formed therein; and the ratio of area occupied by the vias in the via-level insulating interlayers contained in the lower multi-layered interconnect structure is smaller than the ratio of area occupied by the vias in the via-level insulating interlayers contained in the upper multi-layered interconnect structure. |
| US08310055B2 |
Semiconductor devices having narrow conductive line patterns and related methods of forming such semiconductor devices
Semiconductor devices and methods of forming semiconductor devices are provided in which a plurality of patterns are simultaneously formed to have different widths and the pattern densities of some regions are increased using double patterning. The semiconductor device includes a plurality of conductive lines each including a first line portion and a second line portion, where the first line portion extends on a substrate in a first direction, the second line portion extends from one end of the first line portion in a second direction, and the first direction is different from the second direction; a plurality of contact pads each of which is connected with a respective conductive line of the plurality of conductive lines via the second line portion of the corresponding conductive line; and a plurality of dummy conductive lines each including a first dummy portion extending from a respective contact pad of the plurality of contact pads, in parallel with the corresponding second line portion in the second direction. |
| US08310054B2 |
Semiconductor device manufacturing method and target substrate processing system
A semiconductor device manufacturing method includes removing copper deposits, by use of an organic acid gas and an oxidizing gas, from a surface of a second interlayer insulation film having a groove formed therein and reaching a copper-containing electric connector member. The second interlayer insulation film is disposed on a first interlayer insulation film provided with the electric connector member. The method then includes reducing a surface of the electric connector member exposed at a bottom of the groove of the second interlayer insulation film; forming a barrier layer on the second interlayer insulation film; and forming a copper-containing conductive film to fill the groove of the second interlayer insulation film. |
| US08310053B2 |
Method of manufacturing a device with a cavity
A micro-device with a cavity, the micro-device including a substrate. A method of forming the micro-device includes the steps of: A) providing the substrate having a surface and comprising a sacrificial oxide region at the surface; B) covering the sacrificial oxide region with a porous layer being permeable to a vapor HF etchant; and C) selectively etching the sacrificial oxide region through the porous layer using the vapor HF etchant to obtain the cavity. This method may be used in the manufacture of various micro-devices with a cavity , i.e. MEMS devices, and in particular in the encapsulation part thereof, and semiconductor devices, and in particular the BEOL-part thereof. |
| US08310050B2 |
Electronic device package and fabrication method thereof
A chip package is disclosed. The package includes a carrier substrate, at least two semiconductor chips, a fill material layer, a protective layer, and a plurality of conductive bumps. The carrier substrate includes a grounding region. The semiconductor chips are disposed overlying the grounding region of the carrier substrate. Each semiconductor chip includes at least one signal pad and includes at least one grounding pad electrically connected to the grounding region. The fill material layer is formed overlying the carrier substrate and covers the semiconductor chips. The protective layer covers the fill material layer. The plurality of conductive bumps is disposed overlying the protective layer and is electrically connected to the semiconductor chips. A fabrication method of the chip package is also disclosed. |
| US08310048B2 |
Microelectronic devices
Microelectronic devices and methods for manufacturing microelectronic devices are disclosed herein. An embodiment of one such method includes forming a plurality of through holes in a substrate with the through holes arranged in arrays, and attaching a plurality of singulated microelectronic dies to the substrate with an active side of the individual dies facing toward the substrate and with a plurality of terminals on the active side of the individual dies aligned with corresponding holes in the substrate. The singulated dies are attached to the substrate after forming the holes in the substrate. |
| US08310046B2 |
Wafer stacked package waving bertical heat emission path and method of fabricating the same
A wafer stacked semiconductor package (WSP) having a vertical heat emission path and a method of fabricating the same are provided. The WSP comprises a substrate on which semiconductor chips are mounted; a plurality of semiconductor chips stacked vertically on the substrate; a cooling through-hole formed vertically in the plurality of semiconductor chips, and sealed; micro holes formed on the circumference of the cooling through-hole; and coolant filling the inside of the cooling through-hole. Accordingly, the WSP reduces a temperature difference between the semiconductor chips and quickly dissipates the heat generated by the stacked semiconductor chips. |
| US08310044B2 |
Semiconductor device and method of manufacturing the same
The heat-release properties of semiconductor device are to be improved and the reliability thereof is to be improved.The semiconductor device has a wiring substrate, a heat-releasing plate having a convex part inserted into a through-hole of the wiring substrate, a semiconductor chip mounted over the convex part of the heat-releasing plate, and a bonding wire coupling an electrode pad of the semiconductor chip with a bonding lead of the wiring substrate, and further has a sealing portion covering a portion of an upper surface of the wiring substrate, a sealing portion covering a portion of a lower surface of the wiring substrate including the semiconductor chip and the bonding wire, and a solder ball placed over a lower surface of the wiring substrate. In manufacturing the semiconductor device, the heat-releasing plate is positioned at the upper surface side of the wiring substrate such that the convex part is positioned in the through-hole, and a groove in the main surface of the convex part is forcibly widened to swage the convex part and to be fixed to the wiring substrate. |
| US08310041B2 |
Stacked semiconductor package and stacking method thereof
A stacked semiconductor package technique applicable to semiconductor chips having pins short enough that the semiconductor chips cannot be directly bonded together is provided. A printed circuit board (PCB) is inserted into a space between pins of an upper semiconductor chip and the exterior of bodies of stacked semiconductor chips. The PCB includes a plurality of conductive patterns at locations corresponding to the respective pins. The respective conductive patterns and the corresponding respective pins of the upper and lower semiconductor chips are bonded together. The PCB includes a plurality of recess patterns on one side, the recess patterns having the same pitch as the pins of the semiconductor chips. The PCB is disposed across the pins of the lower semiconductor chip, and thereby easily arranged with the stacked semiconductor chips. |
| US08310030B2 |
III-nitride crystal substrate and III-nitride semiconductor device
Affords methods of manufacturing bulk III-nitride crystals whereby at least the surface dislocation density is low globally. The present III-nitride crystal manufacturing method includes: a step of preparing an undersubstrate (1) containing a III-nitride seed crystal, the III-nitride seed crystal having a matrix (1s), and inversion domains (1t) in which the polarity in the <0001> directions is inverted with respect to the matrix (1s); and a step of growing a III-nitride crystal (10) onto the matrix (1s) and inversion domains (it) of the undersubstrate (1) by a liquid-phase technique; and is characterized in that a first region (10s), being where the growth rate of III-nitride crystal (10) growing onto the matrix (1s) is greater, covers second regions (10t), being where the growth rate of III-nitride crystal (10) growing onto the inversion domains (1t) is lesser. |
| US08310029B2 |
Group III nitride semiconductor free-standing substrate and method of manufacturing the same, group III nitride semiconductor device and method of manufacturing the same
A group III nitride semiconductor free-standing substrate includes an as-grown surface, more than half of a region of the as-grown surface including a single crystal plane. The single crystal plane includes an off-angle inclined in an m-axis or a-axis direction from a C-plane with a group III polarity, or in a c-axis or a-axis direction from an M-plane. |
| US08310028B2 |
Semiconductor device with crystal defect and manufacturing method thereof
A semiconductor device includes a semiconductor substrate that is made of either of silicon carbide (SiC) and gallium nitride (GaN), and has a defect region containing a crystal defect; a first insulating film that coats the defect region and is arranged on the semiconductor substrate; and a conductor film that electrically connects to a principal surface of the semiconductor substrate, the principal surface being exposed to a region that is not coated with the first insulating film. |
| US08310023B2 |
Light emitting diode package and fabrication method thereof
The present invention provides an LED package and the fabrication method thereof. The present invention provides an LED package including a submount silicon substrate and insulating film and electrode patterns formed on the submount silicon substrate. The LED package also includes a spacer having a through hole, formed on the electrode patterns. The LED package further includes an LED received in the through hole, flip-chip bonded to the electrode patterns, and an optical element attached to the upper surface of the spacer. |
| US08310022B2 |
Photoconductive materials and devices with internal photoconductive gain
The invention provides a new class of photoconductive materials and devices, and methods for obtaining high internal photoconductive gain. The devices include a semiconductor or material with an electronic band gap provided in a confined geometry and which exhibits multi-exciton generation (MEG) when illuminated with photons with energies above the threshold for MEG. Due to carrier-carrier Coulombic interactions, multi-excitons within the confined material efficiently recombine via Auger recombination, in which a carrier from one exciton is excited to a higher energy level relative to the band edge. Carriers excited by Auger recombination are subsequently trapped by trap states that capture carriers excited high above the band edge more efficiently than carriers near the band edge. Carriers trapped by the trap states allow for the collection and recirculation of untrapped carriers of opposite charge when used as a photoconductive device, producing high internal photoconductive gain. |
| US08310019B2 |
Magnetic memory device
A magnetic memory device includes a magnetic tunnel junction (MTJ) structure and an electrode embedded in a dielectric structure. The MTJ structure includes a free layer. The electrode is formed of silicon-germanium and is electrically connected to the MTJ. The electrode heats the free layer to reduce the coercive force of the free layer to reduce a critical current density. |
| US08310018B2 |
Ferromagnetic semiconductor, method for the production thereof, components incorporating the same, and corresponding uses of said semiconductor
The inventive ferromagnetic semiconductor comprises at least one magnetic element selected from the group consisting of Mn, Fe, Co, Ni and Cr, and has a Curie temperature which is equal to or higher than 350 K, and advantageously 400 K or higher. The semiconductor has a matrix which is depleted in magnetic element(s) and contains a discontinuous phase which is formed from columns, enriched with magnetic elements, and is ferromagnetic up to said Curie temperature, in such a way as to generate a lateral modulation of the composition of the semiconductor in the plane of the thin layer. Also disclosed is a method for the production of the semiconductor, a diode-type electronic component for the injection or collection of spins into or from another semiconductor respectively, or an electronic component which is sensitive to a magnetic field, and uses of the semiconductor relating to such a component. |
| US08310015B2 |
Sensor platform using a horizontally oriented nanotube element
Sensor platforms and methods of making them are described, and include platforms having horizontally oriented sensor elements comprising nanotubes or other nanostructures, such as nanowires. Under certain embodiments, a sensor element has an affinity for an analyte. Under certain embodiments, such a sensor element comprises one or more pristine nanotubes, and, under certain embodiments, it comprises derivatized or functionalized nanotubes. Under certain embodiments, a sensor is made by providing a support structure; providing a collection of nanotubes on the structure; defining a pattern within the nanotube collection; removing part of the collection so that a patterned collection remains to form a sensor element; and providing circuitry to electrically sense the sensor's electrical characterization. Under certain embodiments, the sensor element comprises pre-derivatized or pre-functionalized nanotubes. Under certain embodiments, sensor material is derivatized or functionalized after provision on the structure or after patterning. Under certain embodiments, a large-scale array includes multiple sensors. |
| US08310014B2 |
Field effect transistors, methods of fabricating a carbon-insulating layer using molecular beam epitaxy and methods of fabricating a field effect transistor
Field effect transistors, methods of fabricating a carbon insulating layer using molecular beam epitaxy and methods of fabricating a field effect transistor using the same are provided, the methods of fabricating the carbon insulating layer include maintaining a substrate disposed in a molecular beam epitaxy chamber at a temperature in a range of about 300° C. to about 500° C. and maintaining the chamber in vacuum of 10−11 Torr or less prior to performing an epitaxy process, and supplying a carbon source to the chamber to form a carbon insulating layer on the substrate. The carbon insulating layer is formed of diamond-like carbon and tetrahedral amorphous carbon. |
| US08310012B2 |
Semiconductor device having metal gate and manufacturing method thereof
A semiconductor device includes a semiconductor substrate, a gate dielectric layer formed on the semiconductor substrate, and at least a first conductive-type metal gate formed on the gate dielectric layer. The first conductive-type metal gate includes a filling metal layer and a U-type metal layer formed between the filling metal layer and the gate dielectric layer. A topmost portion of the U-type metal layer is lower than the filling metal layer. |
| US08310004B2 |
Semiconductor device and process for producing the same
A trench gate transistor whose gate changes depth intermittently in the gate width direction, has a first offset region and a second offset region formed below the source and drain, respectively. The first offset region and the second offset region are shallower where they contact the device isolation film than is the device isolation film in those areas. The first and second offset regions nevertheless extend below the bottom of the trench. |
| US08310003B2 |
Solid-state imaging device with vertical gate electrode and method of manufacturing the same
A charge accumulation region of a first conductivity type is buried in a semiconductor substrate. A charge transfer destination diffusion layer of the first conductivity type is formed on a surface of the semiconductor substrate. A transfer gate electrode is formed on the charge accumulation region, and charge is transferred from the charge accumulation region to the charge transfer destination diffusion layer. |
| US08310002B2 |
Semiconductor device and method of forming the same
A semiconductor device includes a semiconductor substrate, a first diffusion region, a gate insulating film, a gate electrode, a second diffusion region and a contact plug. The semiconductor substrate includes a base and at least a pillar. The first diffusion region is disposed in the base. The gate insulating film covers a side surface of the pillar. The gate electrode is separated from the pillar by the gate insulating film. The second diffusion region is disposed in an upper portion of the pillar. The contact plug is connected to the second diffusion region. The contact plug is connected to the entirety of the top surface of the pillar. |
| US08309996B2 |
CMOS image sensors
Complementary metal-oxide semiconductor (CMOS) image sensors (CIS) and methods of manufacturing the same are provided, the sensors include an epitaxial layer on a substrate in which a first, second, third and fourth region are defined. A photodiode may be formed at an upper portion of the epitaxial layer in the first region. A plurality of gate structures may be formed on the epitaxial layer in the second, third and fourth regions. A first blocking layer may be formed on the gate structures and the epitaxial layer in the first and second regions. A first impurity layer may be formed at an upper portion of the epitaxial layer adjacent to the gate structures in the second region, and a second impurity layer at upper portions of the epitaxial layer adjacent to the gate structures in the third and fourth regions. A color filter layer may be formed over the photodiode. A microlens may be formed on the color filter layer. |
| US08309990B2 |
Integrated devices on a common compound semiconductor III-V wafer
A III-V compound semiconductor structure comprises epitaxial structures that include an integrated pair of different types of active devices. The semiconductor structure includes a semi-insulating substrate of a compound semiconductor III-V material and a first compound semiconductor III-V epitaxial structure disposed on the substrate. A concentration profile of dopant material in the semiconductor structure decreases substantially smoothly across an interface between the substrate and the first epitaxial structure in a direction from the first epitaxial structure toward the substrate, and continues to decrease substantially smoothly from the interface with increasing depth into the substrate despite the presence of silicon or oxygen contaminant at the interface. The interface is substantially free of a second contaminant that was present, during formation of the first epitaxial structure, in a chamber in which the first epitaxial structure was formed. |
| US08309989B2 |
Tunneling field-effect transistor with low leakage current
Illustrative embodiments of a vertical tunneling field effect transistor are disclosed which may comprise a semiconductor body including a source region doped with a first dopant type and a pocket region doped with a second dopant type, where the pocket region is formed above the source region. The transistor may also comprise an insulated gate formed above the source and pocket regions, the insulated gate being configured to generate electron tunneling between the source and pocket regions if a voltage is applied to the insulated gate. The transistor may further comprise a lateral tunneling barrier formed to substantially prevent electron tunneling between the source region and a drain region of the semiconductor body, where the drain region is doped with the second dopant type. |
| US08309986B2 |
Tri-gate field-effect transistors formed by aspect ratio trapping
Semiconductor structures include a trench formed proximate a substrate including a first semiconductor material. A crystalline material including a second semiconductor material lattice mismatched to the first semiconductor material is formed in the trench. Process embodiments include removing a portion of the dielectric layer to expose a side portion of the crystalline material and defining a gate thereover. Defects are reduced by using an aspect ratio trapping approach. |
| US08309985B2 |
Light emitting device
A light emitting device is provided with: a pair of an anode and a cathode that are opposed to each other; and a phosphor layer, composed of a plurality of phosphor particles, that is sandwiched between the paired anode and cathode, from direction that is perpendicular to main surfaces of the anode and the cathode, and in this structure, each phosphor particle is a nitride semiconductor phosphor particle having a wurtzite crystal structure that contains an n-type nitride semiconductor portion and a p-type nitride semiconductor portion, with the n-type nitride semiconductor portion being made in contact with the cathode and the p-type nitride semiconductor portion being made in contact with the anode, and the n-type nitride semiconductor portion and the p-type nitride semiconductor portion have the common c-axe in the respective crystal structures thereof made in parallel with each other, with the n-type nitride semiconductor portion and the p-type nitride semiconductor portion being made in contact with each other on a plane in parallel with the c-axe. |
| US08309982B2 |
Group-III nitride semiconductor light-emitting device, method for manufacturing the same, and lamp
Provided is a group-III nitride semiconductor light-emitting device which has a high level of crystallinity and superior internal quantum efficiency and which is capable of enabling acquisition of high level light emission output, and a manufacturing method thereof, and a lamp. An AlN seed layer composed of a group-III nitride based compound is laminated on a substrate 11, and on this AlN seed layer, there are sequentially laminated each layer of an n-type semiconductor layer, a light-emitting layer, and a p-type semiconductor layer respectively composed of a group-III nitride semiconductor, wherein the full width at half-maximum of the X-ray rocking curve of the (0002) plane of the p-type semiconductor layer 16 is 60 arcsec or less, and the full width at half-maximum of the X-ray rocking curve of the (10-10) plane is 250 arcsec or less. |
| US08309979B2 |
Electrically isolated vertical light emitting diode structure
A light emitting device is provided having high luminous output while maintaining high wall plug efficiency, wherein the high thermal and electrical conductivity paths of the device are separated during the semiconductor wafer and die level manufacturing step. The device includes an electrical conducting mirror layer, which reflects at least 60% of generated light incident on it, and an isolation layer having electrical insulating properties and thermal conducting properties. A first electrode, which is not in contact with the main semiconductor layers of the device, is located on the mirror layer. A light emitting module, system and projection system incorporating the light emitting device are also described, as is a method of manufacture of the device. |
| US08309978B2 |
LED module and LED lamp having the LED module
An LED module includes a first dielectric layer, and a first patterned conductive layer having first, second, and third die-bonding pads. Each die-bonding pad includes a pad body having a die-bonding area, and an extension extended from the pad body. The extension of the first die-bonding pad extends in proximity to the die-bonding area of the second die-bonding pad. The extension of the second die-bonding pad extends in proximity to the die-bonding area of the third die-bonding pad. A second dielectric layer disposed on the first patterned conductive layer includes three dielectric members corresponding respectively to the die-bonding pads of the first patterned conductive layer. Each dielectric member includes a chip-receiving hole exposing the die-bonding area of a respective die-bonding pad for attachment of an LED chip thereto, and a wire-passage hole spaced apart from the chip-receiving hole to expose partially the first patterned conductive layer for bonding a wire. |
| US08309976B2 |
Light emitting device and manufacturing method thereof
A light emission device manufactured by a method of forming a curved surface having a radius of curvature to the upper end of an insulator 19, exposing a portion of the first electrode 18c to form an inclined surface in accordance with the curved surface, and applying etching so as to expose the first electrode 18b in a region to form a light emission region, in which emitted light from the layer containing the organic compound 20 is reflected on the inclined surface of the first electrode 18c to increase the total take-out amount of light in the direction of an arrow shown in FIG. 1A and, further, forming a light absorbing multi-layered film 24 comprising light absorbing multi-layered film on the first electrode 18c other than the region to form the light emission region, thereby obtaining a light emission device of a structure increasing the amount of light emission taken out in one direction in a light emission element, while not all the light formed in the layer containing the organic compound are taken out from the cathode as a transparent electrode toward TFT but the light was emitted also, for example, in the lateral direction (direction parallel with the plane of the substrate). |
| US08309975B2 |
Semiconductor light emitting element and semiconductor light emitting device using the same
In a semiconductor light emitting device, in which a light emitting layer is formed on one surface of a conductive substrate, and an n-type electrode and a p-type electrode are formed on the same side as the light emitting layer, there has been the problem that, if larger electric power is applied, heat is generated near the n-side electrode to reduce luminous efficiency. The n-side electrode has a predetermined length at a corner portion or along an edge of the substrate to disperse a current flowing from the n-side electrode into the substrate, thereby avoiding heat generation near the n-side electrode. In this type of semiconductor light emitting element, the existence of the n-side electrode reduces a light emitting area. Therefore, the length of the n-side electrode preferably ranges from 20% to 50% of the entire peripheral length of the substrate. |
| US08309974B2 |
Light emitting diode package
To provide a light emitting diode package of which the height of protrusion of a thermal via is decreased without decreasing the flexural strength of an insulating substrate.A light emitting diode package comprising a light emitting diode element mounted on a substrate, wherein the substrate is obtained by firing a glass ceramic composition containing a powder of glass containing, as represented by mole percentage, from 57 to 65% of SiO2, from 13 to 18% of B2O3, from 9 to 23% of CaO, from 3 to 8% of Al2O3 and from 0.5 to 6% of at least one of K2O and Na2O in total, and a ceramic filler. |
| US08309971B2 |
Light emitting diode having electrode pads
Exemplary embodiments of the present invention relate to a including a substrate, a first conductive type semiconductor layer arranged on the substrate, a second conductive type semiconductor layer arranged on the first conductive type semiconductor layer, an active layer disposed between the first conductive type semiconductor layer and the second conductive type semiconductor layer, a first electrode pad electrically connected to the first conductive type semiconductor layer, a second electrode pad arranged on the second conductive type semiconductor layer, an insulation layer disposed between the second conductive type semiconductor layer and the second electrode pad, and at least one upper extension electrically connected to the second electrode pad, the at least one upper extension being electrically connected to the second conductive type semiconductor layer. |
| US08309970B2 |
Vertical structure LED device and method of manufacturing the same
A method of manufacturing a vertical structure light emitting diode device, the method including: sequentially forming a first conductivity type III-V group compound semiconductor layer, an active layer, and a second conductivity type III-V group compound semiconductor layer on a substrate for growth; bonding a conductive substrate to the second conductivity type III-V group compound semiconductor layer; removing the substrate for growth from the first conductivity type III-V group compound semiconductor layer; and forming an electrode on an exposed portion of the first conductive III-V group compound semiconductor layer due to the removing the substrate for growth, wherein the bonding a conductive substrate comprises partially heating a metal bonding layer by applying microwaves to a bonding interface while bringing the metal bonding layer into contact with the bonding interface. |
| US08309967B2 |
Diamond LED devices and associated methods
LED devices incorporating diamond materials and methods for making such devices are provided. One such method may include forming epitaxially a substantially single crystal SiC layer on a substantially single crystal Si wafer, forming epitaxially a substantially single crystal diamond layer on the SiC layer, doping the diamond layer to form a conductive diamond layer, removing the Si wafer to expose the SiC layer opposite to the conductive diamond layer, forming epitaxially a plurality of semiconductor layers on the SiC layer such that at least one of the semiconductive layers contacts the SiC layer, and coupling an n-type electrode to at least one of the semiconductor layers such that the plurality of semiconductor layers is functionally located between the conductive diamond layer and the n-type electrode. |
| US08309966B2 |
Gate driver on array of a display
A gate driver on array of a display includes a substrate having a peripheral region, and a gate driver on array structure formed in the peripheral region. The gate driver on array structure includes a pull-down transistor, and the pull-down transistor has a gate electrode, an insulating layer, a semiconductor island, a source electrode, and a drain electrode. The semiconductor island extends out of both edges of the gate electrode, and extends out of an edge of the source electrode and an edge of the drain electrode. |
| US08309965B2 |
Display device and manufacturing method thereof
Provided is a display device including a thin-film transistor and a capacitor element, the thin-film transistor includes: a first insulating film (IN1) which is formed to cover an area where a gate electrode (GT) is formed; a second insulating film (IN2) which is formed on the first insulating film, the second insulating film having an opening (OP) formed in the area in plan view; a semiconductor layer (SCLt) which is formed on the second insulating film to cross the opening, the semiconductor layer including high concentration areas (CN); a third insulating film (IN3) which is formed on the semiconductor layer to expose apart of each of the high concentration areas; and a pair of electrodes (DT, ST) each having electrical connection to the part; and the capacitor element includes a dielectric film which is formed of the same layer and the same material as the third insulating film. |
| US08309959B2 |
Display device having opening portion with different widths
A display device which surely allows the black-spot-forming correction at the time of forming an opening portion in a portion of a scanning signal line where a scanning signal line and a video signal line intersects each other and forming a semiconductor layer and a conductor layer by a resist flow method is provided. A scanning signal line which forms an opening portion in a portion thereof which intersects a video signal line, an insulation film, a semiconductor layer which covers a region which spreads larger than a conductor layer, and the conductor layer are sequentially stacked. The conductor layer includes the video signal line, a drain electrode and a source electrode of a thin film transistor, and a connecting line which connects the video signal line and the drain electrode. The connecting line is branched from the video signal line over the opening portion, and the opening portions is formed in a projecting manner toward both edges of the scanning signal line such that a width of the opening portion in the direction which intersects the connecting line is set larger than a width of the semiconductor layer. |
| US08309957B2 |
Replacement of scribeline padframe with saw-friendly design
An integrated circuit substrate containing an electrical probe pad structure over, and on both sides of, a dicing kerf lane. The electrical probe pad structure includes metal crack arresting strips adjacent to the dicing kerf lane. A metal density between the crack arresting strips is less than 70 percent. An electrical probe pad structure containing metal crack arresting strips, with a metal density between the crack arresting strips less than 70 percent. A process of forming an integrated circuit by forming an electrical probe pad structure over a dicing kerf lane adjacent to the integrated circuit, such that the electrical probe pad structure has metal crack arresting strips adjacent to the dicing kerf lane, and performing a dicing operation through the electrical probe pad structure. |
| US08309953B2 |
Transistor structures and methods of fabrication thereof
An electronic device is presented, such as a thin film transistor. The device comprises a patterned electrically-conductive layer associated with an active element of the electronic device. The electrically-conductive layer has a pattern defining an array of spaced-apart electrically conductive regions. This technique allows for increasing an electric current through the device. |
| US08309952B2 |
Thin film transistor and method for manufacturing the same
One embodiment of the present invention is a thin film transistor, including: an insulating substrate; a gate electrode and a gate insulator being formed on the insulating substrate, in this order; a source electrode and a drain electrode formed on the gate insulator, surface preparation of the source electrode and the drain electrode being performed with a compound having a functional group with an electron-withdrawing property; and a semiconductor film formed on the gate insulator, the film being formed between the source electrode and the drain electrode. |
| US08309948B2 |
Nitride semiconductor device
In the nitride semiconductor device of the present invention, an active layer 12 is sandwiched between a p-type nitride semiconductor layer 11 and an n-type nitride semiconductor layer 13. The active layer 12 has, at least, a barrier layer 2a having an n-type impurity; a well layer 1a made of a nitride semiconductor that includes In; and a barrier layer 2c that has a p-type impurity, or that has been grown without being doped. An appropriate injection of carriers into the active layer 12 becomes possible by arranging the barrier layer 2c nearest to the p-type layer side. |
| US08309945B2 |
Programmable metallization memory cell with planarized silver electrode
Programmable metallization memory cells having a planarized silver electrode and methods of forming the same are disclosed. The programmable metallization memory cells include a first metal contact and a second metal contact, an ion conductor solid electrolyte material is between the first metal contact and the second metal contact, and either a silver alloy doping electrode separates the ion conductor solid electrolyte material from the first metal contact or the second metal contact, or a silver doping electrode separates the ion conductor solid electrolyte material from the first metal contact. The silver electrode includes a silver layer and a metal seed layer separating the silver layer from the first metal contact. |
| US08309942B2 |
Self-powered environmental sensor with wake-up circuitry
A self-powered sensor (e.g., 100, 180, 220, 400) can wake-up systems requiring a trigger signal to wake-up circuits or systems in power-sleep mode, conserving the battery power for emergency computations and communications. In a humidity sensor embodiment 100, radioisotope generated voltage biases are employed to power sensor capacitors to realize self-powered sensors. A first self-powered capacitor biasing architecture 160 is based on changes in the leakage resistance of the polymer capacitor 110, and a second self-powered capacitor biasing architecture 140 uses changes in the capacitance of the polymer capacitor. Another sensor embodiment uses changes in the capacitance or leakage resistance of the sensor capacitor to modulate conductance of a MOSFET 114, realizing an easily readable electronic output signal. A temperature sensor embodiment 180 and a MEMS cantilever structure based fissile material proximity sensor embodiment 400 are also disclosed. |
| US08309940B2 |
Lighting design of high quality biomedical devices
The invention relates to a plurality of light sources to power a variety of applications including microarray readers, microplate scanners, microfluidic analyzers, sensors, sequencers, Q-PCR and a host of other bioanalytical tools that drive today's commercial, academic and clinical biotech labs. |
| US08309938B2 |
Ion beam incident angle detection assembly and method
In an ion implanter, a detector assembly is employed to monitor the ion beam current and incidence angle at the location of the work piece or wafer. The detector assembly includes a plurality of pairs of current sensors and a blocker panel. The blocker panel is disposed a distance away from the sensors to allow certain of the beamlets that comprise the ion beam to reach the sensors. Each sensor in a pair of sensors measures the beam current incident thereon and the incident angle is calculated using these measurements. In this manner, beam current and incidence angle variations may be measured at the work piece site and be accommodated for, thereby avoiding undesirable beam current profiles. |
| US08309937B2 |
Grid providing beamlet steering
A grid assembly coupled to a discharge chamber of an ion beam source is configured for steering ion beamlets emitted from the discharge chamber at circularly asymmetrically determined steering angles. The grid assembly includes at least first and a second grid with a substantially circular pattern of holes, wherein each grid comprises holes positioned adjacent to one another. A plurality of the holes of the second grid is positioned with offsets relative to corresponding holes in the first grid. Due to the offsets in the holes in the second grid, ions passing through the offset holes are electrostatically attracted towards the closest circumferential portion of the downstream offset holes. Thus, the trajectories of ions passing through the offset holes are altered. The beamlet is steered by predetermined asymmetric angles. The predetermined steering angles are dependent upon the hole offsets, voltage applied to the grids, and the distance between the grids. |
| US08309934B2 |
High radiation environment tunnel monitoring system and method
In accordance with the principles of the present invention utilizing a first radiation monitoring module, radiation information associated with the first radiation monitoring module within a tunnel is wirelessly transmitted to a second radiation monitoring module. The second radiation monitoring module is able to receive radiation information from the first radiation monitoring module for relay of the received radiation information to a central monitoring system. The radiation monitoring modules of the present invention allow long term monitoring of a tunnel's radiation levels with maintenance simply requiring replacement of a non-operational tunnel monitoring module by a robot. |
| US08309930B2 |
Method of local electro-magnetic field enhancement of terahertz (THz) radiation in sub- wavelength regions and improved coupling of radiation to materials through the use of the discontinuity edge effect
A method and apparatus for enhanced THz radiation coupling to molecules, includes the steps of depositing a test material near the discontinuity edges of a slotted member, and enhancing the THz radiation by transmitting THz radiation through the slots. The molecules of the test material are illuminated by the enhanced THz radiation that has been transmitted through the slots, thereby producing an increased coupling of EM radiation in the THz spectral range to said material. The molecules can be bio-molecules, explosive materials, or species of organisms. The slotted member can be a semiconductor film, a metallic film, in particular InSb, or layers thereof. THz detectors sense near field THz radiation that has been transmitted through said slots and the test material. |
| US08309929B2 |
Tunable photonic cavities for in-situ spectroscopic trace gas detection
Compact tunable optical cavities are provided for in-situ NIR spectroscopy. MEMS-tunable VCSEL platforms represents a solid foundation for a new class of compact, sensitive and fiber compatible sensors for fieldable, real-time, multiplexed gas detection systems. Detection limits for gases with NIR cross-sections such as O2, CH4, COx and NOx have been predicted to approximately span from 10ths to 10s of parts per million. Exemplary oxygen detection design and a process for 760 nm continuously tunable VCSELS is provided. This technology enables in-situ self-calibrating platforms with adaptive monitoring by exploiting Photonic FPGAs. |
| US08309925B2 |
Resonant cavity integrated into a waveguide for terahertz sensing
A method comprising polarizing and coupling an electromagnetic beam to a first-order transverse electric (TE1) mode with respect to a parallel plate waveguide (PPWG) integrated resonator comprising two plates and a cavity, sending the electromagnetic beam into the PPWG integrated resonator to excite the cavity by the TE1 mode and cause a resonance response, and obtaining wave amplitude data that comprises a resonant frequency, and obtaining the refractive index of fluids filling the cavity via the shift in resonant frequency. |
| US08309922B2 |
Semiconductor inspection method and device that consider the effects of electron beams
Disclosed is a device capable of probing with minimal effect from electron beams. Rough probing is made possible using a lower magnification than the magnification usually viewed. When target contact of semiconductor is detected, measurement position is set in the center of picture usually to move probe without moving stage. With the miniaturization, contact can be confirmed only at high magnification, although probe can be confirmed at low magnification on the contrary but it is necessary to display it in real time. Static image obtained at high magnification once is combined with image obtained at low magnification in real time from target contact required for probing and characteristic of probe to be displayed, so that probing at low magnification can be realized to reduce the effects of electron beams and obtain accurate electrical characteristics. |
| US08309920B2 |
Sample milling/observing apparatus and method of observing sample
When a sample is cut to update an observed section, an electron beam is focused on the observed section. An apparatus of the invention includes an ion gun 102 which irradiates an ion beam onto a sample 200 to form an observed section 202, an electron gun 104 which irradiates an electron beam EB onto the observed section 202 formed by the ion gun 102, a focal point adjusting unit 106 which adjusts a relationship between the observed section 202 and a focal point of the electron beam EB, and a focal point control unit 108 which controls the focal point adjusting unit 106 on the basis of an amount of cut of the sample 200 obtained by irradiation of the ion beam IB obtained by the ion gun 102. |
| US08309916B2 |
Ion transfer tube having single or multiple elongate bore segments and mass spectrometer system
An ion transfer tube for a mass spectrometer comprises a tube member having an inlet end and an outlet end; and at least one bore extending through the tube member from the inlet end to the outlet end, the at least one bore having a non-circular cross section. A method of forming an ion transfer tube comprises the steps of providing a tube member having a length and an internal bore, the internal bore having a wall of circular cross section; and etching or eroding portions of the tube member adjacent to the wall so as to form an enlarged bore having a non-circular cross section. |
| US08309915B2 |
Mass spectrometer using an accelerating traveling wave
A mass spectrogram employs a set of controllable electrodes to produce a time varying axially inhomogenous electric field and enhance separation of charged particles by exposing the charged particles to different electric field strengths based on their spatial positions. The fields may be tailored to provide a traveling wave that expands portions of a spectrographic plot of the particles and/or to provide focusing or other effects. |
| US08309914B2 |
Method of operating a linear ion trap to provide low pressure short time high amplitude excitation with pulsed pressure
Methods for fragmenting ions in an ion trap are described. These methods involve a) selecting parent ions for fragmentation; b) retaining the parent ions within the ion trap for a retention time interval, the ion trap having an operating pressure of less than about 1×10−4 Torr; c) providing a RF trapping voltage to the ion trap to provide a Mathieu stability parameter q at an excitement level during an excitement time interval within the retention time interval; d) providing a resonant excitation voltage to the ion trap during the excitement time interval to excite and fragment the parent ions; e) providing a non-steady-state pressure increase of at least 10% of the operating pressure within the ion trap by delivering a neutral gas into the ion trap for at least a portion of the retention time interval to raise the pressure in the ion trap to a varying first elevated-pressure in the range between about 6×10−5 Torr to about 5×10−4 Torr for a first elevated-pressure duration; and f) within the retention time interval and after the excitement time interval, terminating the resonant excitation voltage and changing the RF trapping voltage applied to the ion trap to reduce the Mathieu stability parameter q to a hold level less than the excitement level to retain fragments of the parent ions within the ion trap. The excitation time interval and the first elevated-pressure duration substantially overlap in time. |
| US08309911B2 |
Methods and apparatus for filling an ion detector cell
In a mass spectrometer, a dual stage axial extraction field is applied to transport ions from an accumulator to a detector cell. Ions of a same mass may be transported to the detector cell or a point axially preceding the detector cell at the same time. This may be done by selecting the relative strengths of a first axial electric field applied to the accumulator and a second axial electric field applied to a shutter located at an exit end of the accumulator. This may also be done by selecting relative axial lengths of the accumulator, shutter, and an ion guide located at an exit end of the shutter. A dual stage decelerating field may also be applied to slow ions down prior to and after entering the detector cell. |
| US08309910B2 |
Phantom for spectral CT image system calibration
A phantom includes a housing enclosing an interior volume and having a plurality of passages formed therein, wherein each passage is fluidly isolated from the interior volume. First and second inserts are included and configured to be positioned in a first passage of the plurality of passages and include materials having a known material density. The material is selected from iodine, hydroxyapatite (HAP), tricalcium phosphate (TCP), body fat, fatty plaque, sodium chloride (NaCl), gold (Au), and iron (Fe). The material of the inserts can be different materials or the same material at different densities. |
| US08309909B2 |
AtomChip device
An AtomChip device and a method for trapping, manipulating and measuring atoms in ultra high vacuum chamber, and for increasing the lifetime of the trapped atoms, the AtomChip device including at least one conductive element, made of metal, wherein at least part of the metal is a dilute alloy metal, and wherein the at least one conductive element has a low working temperature. |
| US08309906B2 |
Absolute optical encoder with long range intensity modulation on scale
An encoder configuration comprises a dual-modulation scale track pattern that provides a first intensity modulation component for producing periodic signals, and a second intensity modulation component for producing a long-range absolute signal. The dual-modulation scale track pattern increases the range-to-resolution ratio of the encoder without the use of additional scale tracks that would increase the width of the encoder components. The long-range signal may be encoded in the dual-modulation scale track pattern either by varying certain dimensions of pattern elements included in the scale track or by superimposing a layer including an optical density variation along on the track on pattern elements of similar areas. In either case, the net offset and/or amplitude levels of the associated signals are modified along the scale track. These modified offset and/or amplitude levels provide the basis for the long-range absolute signal. |
| US08309904B2 |
Safety system for safeguarding a moving, guided motion element having switchable object detection devices
A safety system for safeguarding a moving, guided motion element against unwanted collisions with an object located on a motion path in the direction of motion of the motion element. The safety system includes an object-detection device for detecting an object in an area of the motion element. The object-detection device can be blocked with respect to object detection by a motion of the motion element, and has an electronic unit with which the motion of the motion element can be controlled and which is configured to assign a blocked state to the object-detection device when the motion element approaches in the blocked state an object or motion element will not trigger a safety mode and when a shut-off signal coming from the motion element is detected, at least part of the object-detection device is transferred into the blocked state. |
| US08309889B2 |
Electrical circuit
An indicating lamp is provided on the exterior of a vent port to indicate failure of a heater within the vent port. An electrical circuit is provided to energize the indicating lamp in response to failure of one or the other of a pair of heaters within the vent port. |
| US08309887B2 |
Arc-welding torch, wear detection system for power supply portion of contact tip, and wear detection method for contact tip
A welding torch includes: a contact tip having, on a distal-end inner circumferential surface thereof, a power supply portion that contacts a fed welding wire to supply current; and a wire guide that is provided having a predetermined clearance within the contact tip and guides the fed welding wire, and wherein the arc-welding torch is configured such that axes of the contact tip and the wire guide are relatively changed so as to cause the welding wire fed while guided by the wire guide to contact the power supply portion of the contact tip. The power supply portion of the contact tip is formed to have an axial length with which a welding current can be maintained at least a predetermined lower limit current despite a shift of a power supply point in accordance with wear of the power supply portion, more specifically, formed to have a length of 1 to 4 mm. |
| US08309884B2 |
Laser irradiation apparatus
The present invention is to provide a laser irradiation apparatus for forming a laser beam which has a shape required for the annealing and which has homogeneous energy distribution, by providing a slit at an image-formation position of a diffractive optical element, wherein the slit has a slit opening whose length is changeable.The laser irradiation apparatus comprises a laser oscillator, a diffractive optical element, and a slit, wherein the slit has a slit opening whose length in a major-axis direction thereof is changeable, wherein a laser beam is delivered obliquely to a substrate, and wherein the laser beam is a continuous wave solid-state, gas, or metal laser, or a pulsed laser with a repetition frequency of 10 MHz or more. |
| US08309874B2 |
Gas heater
A method and apparatus for heating or cooling a fluid. An inlet conduit coupled to a plurality of distribution nozzles in fluid communication with a channel at the periphery of the apparatus. An insert and a sleeve cooperatively define a thin gap, in fluid communication with the channel, through which the fluid flows. Thermal inserts near the thin gap generate heat flux into or out of the fluid, which exits through an outlet conduit. |
| US08309870B2 |
Leveled touchsurface with planar translational responsiveness to vertical travel
Described herein are techniques related to a leveled touchsurface with planar translational responsiveness to vertical travel. Examples of a touchsurface include a key of a keyboard, touchpad of a laptop, or a touchscreen of a smartphone or tablet computer. With the techniques described herein, the touchsurface is constrained to remain in a level orientation during planar translational movement between depressed and unpressed positions along a diagonal line with respect to a vertical axis. Also, with the techniques described herein, a planar-translation-effecting mechanism imparts a planar translation to the touchsurface while it travels vertically (e.g., downward) as the user presses the touchsurface. This Abstract is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. |
| US08309868B2 |
Miniature switch connector
The invention relates to a Switch connector for mounting on a printed circuit board, adapted to receive a mating connector in an insertion direction along an insertion axis. The switch connector comprises a shield, a contact element, and a contact spring having at least one fixed leg, at least one elastically deflectable switching leg, and at least one spring bend, the fixed leg and the switching leg extending from the spring bend in a common direction and passing the insertion axis. The switching leg is adapted to be moved by insertion of the mating connector from a rest position, at which the switching leg exerts a spring force onto the contact element, to a switching position, at which the switching leg is spaced apart from the contact element, at least one spring force flux that in the rest position is generated by the switching leg and guided in a closed loop to the fixed leg. To increase the reliability of the switching function, the shield is arranged in the closed loop of the spring force flux. |
| US08309866B2 |
Weight checking apparatus having measuring and processing portions
Apparatus for changing a position of device for measuring a weight of an object. The apparatus includes a conveyor portion, a measuring portion which also conveys the object and measures a weight of the object, and a pair of rails which extend along a conveying direction of the object and onto which the conveying and measuring portions are movably attached. |
| US08309864B2 |
Device mounting board and manufacturing method therefor, and semiconductor module
A device mounting board includes: an insulating resin layer; a wiring layer disposed on one main surface of the insulating resin layer; and a bump electrode connected electrically to the wiring layer and protruding on a side of the insulating resin layer from the wiring layer. A side surface of the bump electrode is curved inwardly toward the center axis of the bump electrode as viewed in a cross section including the center axis of the bump electrode, and the radius of curvature of the side surface changes continuously from a wiring layer end to a head end of the bump electrode. |
| US08309863B2 |
Printed wiring board
A printed wiring board includes ground layers stacked via insulator(s), a first through hole, second through holes and signal wirings, each signal wiring extending from the first through hole through the clearance between predetermined ones of the ground layers, and disposed between predetermined second through holes of the second through holes. Each of first clearances in the ground layers neighboring a layer in which the signal wiring is disposed has an outline such that a distance between the first through hole and outline of the first clearance is minimum of the signal wiring. Each of second clearances in the ground layers not adjacent to the signal wiring has an outline formed outside a circle connecting each center of second through holes centering the first signal through hole, such that the outline of second clearance does not contact with the second through holes. |
| US08309860B2 |
Electronic component built-in substrate and method of manufacturing the same
A method of manufacturing an electronic component built-in substrate, includes the steps of mounting a chip-like electronic component having a connection pad and a metal protection layer formed on a whole of one surface to cover the connection pad, on a wiring substrate to direct the connection pad upward; embedding the electronic component with the insulating layer; processing the insulating layer in a thickness direction to leave the insulating layer in a side of the electronic component and to expose the metal protection layer of the electronic component; and forming an upper wiring layer having an in-chip wiring part which is connected to the connection pad and contacts an upper surface of the electronic component and is constructed by an underlying metal pattern layer formed by patterning the metal protection layer and a conductive pattern layer formed thereon, and an extended wiring part which is connected to the in-chip wiring part to extend onto the insulating layer and is formed by an identical layer as the conductive pattern layer. |
| US08309857B2 |
Pattern electrode manufacturing method and pattern electrode
Disclosed is a method of manufacturing a pattern electrode which excels in electroconductivity, transparency and etching property and a pattern electrode, the method comprising a step of applying a metal particle containing solution onto a substrate to form a conductive layer, a step of pattern printing a metal particle removing solution on a portion of the conductive layer, which is to be removed, and a step of washing the resulting printed material, whereby the portion of the conductive layer on which the metal particle removing solution has been printed is removed to form a non-conductive portion. |
| US08309855B2 |
Flexible printed circuit board
A flexible printed circuit board that can be used for mounting a light emitting diode. The flexible printed circuit board includes a lower insulator, an upper insulator, and a conductive pattern disposed between the upper and lower insulators. A white film is attached to the top of the upper insulator. Alternatively, the upper insulator is formed of a white insulation material. The flexible printed circuit board has a planar surface and can be properly assembled to other components. |
| US08309853B2 |
Flexible printed wiring board
A flexible printed wiring board includes a substrate, conductor wirings, a coverlay film, a jumper wiring, and through holes. The conductor wirings are disposed on a first surface of the substrate. The coverlay film covers at least part of the conductor wirings. The jumper wiring electrically connects the conductor wirings to each other. The through holes are formed in the substrate and respectively open to the surfaces of the conductor wirings. The jumper wiring is composed of a hardened material of a conductive paste and is formed so that a second surface of the substrate is continuous with respective surfaces of the conductor wirings to which the through holes open. |
| US08309851B2 |
Insulated wire and manufacturing method of the same
An insulated wire includes a conductor, and an insulating layer of a porous member formed on the conductor by using a water-in-oil type emulsion (W/O emulsion) including a thermosetting liquid solventless varnish as the oil and water drops of water-soluble polymer contained in the thermosetting liquid solventless varnish as the water. The insulating layer of the porous member is formed by that the water-in-oil type emulsion is coated so as to form a thin film as a coated film, the thermosetting liquid solventless varnish as the oil is polymerized and cured after the formation of the thin film, and the water drops as the water is dried and removed after the curing of the thermosetting liquid solventless varnish. |
| US08309850B2 |
Modular cover for cable connectors and accessories
A cable connector cover for use with modular cable protectors includes a bottom recess for housing cables and cable connectors. The cable protector cover also has a number of openings to provide access into the bottom recess. These openings are adjacent to the connectors and are aligned with the channels of the cable protectors to allow cables to run from the cable protectors into the recess. The upper portion of the cable connector cover can extend upward to a sufficient height to provide a visual indicator to passersby. |
| US08309844B2 |
Thick film pastes for fire through applications in solar cells
Formulations and methods of making solar cell contacts and cells therewith are disclosed. The invention provides a photovoltaic cell comprising a front contact, a back contact, and a rear contact. The back contact comprises, prior to firing, a passivating layer onto which is applied a paste, comprising aluminum, a glass component, wherein the aluminum paste comprises, aluminum, another optional metal, a glass component, and a vehicle. The back contact comprises, prior to firing, a passivating layer onto which is applied an aluminum paste, wherein the aluminum paste comprises aluminum, a glass component, and a vehicle. |
| US08309842B2 |
Method and device of diamond like carbon multi-layer doping growth
A method of a:DLC multi-layer doping growth comprising the steps of: forming a plurality of a:DLC layers in one process, thereby creating a plurality of successively connected PIN junctions, starting from a first junction and ending in a last junction, respective PIN junctions having p-type, n-type, and intrinsic layers; varying the sp3/sp2 ratio of at least the respective p-type and n-type layers and doping with at least silver to enhance electron mobility in respective PIN junctions; and connecting the plurality of a:DLC layers between electrodes at the first side and the second side to create a device having optimized spectral response to being oriented to a light source. |
| US08309840B2 |
Solar panel overlay and solar panel overlay assembly
A solar panel overlay for mounting on an underlying roof deck comprises a substrate and at least one row of photovoltaic cells on the substrate. The photovoltaic cells define a solar collecting surface having an appearance mimicking that of the underlying roof deck. A solar panel overlay assembly comprising a plurality of interconnect solar panel overlays is also provided. |
| US08309837B2 |
Tone generation control apparatus
A tone generation apparatus detects a position of a mouthpiece section having been pressed by a human player holding the mouthpiece section in his or her mouth. The tone generation apparatus identifies a tone pitch on the basis of the detected position and human player's operation on a piston control. Also, the tone generation apparatus detects a pressure of breath blown by the human player into the mouthpiece section and generates a tone signal of a wind instrument having the identified tone pitch, and audibly reproduces the tone signal after amplifying the tone signal in accordance with a tone volume level corresponding to the detected pressure of breath. |
| US08309830B2 |
Wheat variety MSU line E0028
A wheat variety designated MSU Line E0028, the plants and seeds of MSU Line E0028, methods for producing a wheat plant produced by crossing the variety E0028 with another wheat plant, and hybrid wheat seeds and plants produced by crossing the variety E0028 with another wheat line or plant, and the creation of variants by mutagenesis or transformation of variety E0028. The present technology also relates to methods for producing other wheat varieties or breeding lines derived from MSU Line E0028 and to wheat varieties or breeding lines produced by those methods. |
| US08309829B2 |
Plants and seeds of hybrid corn variety CH363245
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH363245. The invention thus relates to the plants, seeds and tissue cultures of the variety CH363245, and to methods for producing a corn plant produced by crossing a corn plant of variety CH363245 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH363245. |
| US08309821B2 |
Plants and seeds of hybrid corn variety CH746304
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH746304. The invention thus relates to the plants, seeds and tissue cultures of the variety CH746304, and to methods for producing a corn plant produced by crossing a corn plant of variety CH746304 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH746304. |
| US08309819B1 |
Maize variety PHRDC
A novel maize variety designated PHRDC and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PHRDC with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PHRDC through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PHRDC or a trait conversion of PHRDC with another maize variety. Inbred maize varieties derived from maize variety PHRDC, methods for producing other inbred maize varieties derived from maize variety PHRDC and the inbred maize varieties and their parts derived by the use of those methods. |
| US08309818B2 |
Insect resistant cotton plants and methods for identifying same
The invention provides specific transgenic cotton plants, plant material and seeds, characterized in that these products harbor a specific transformation event at a specific location in the cotton genome. Tools are also provided which allow rapid and unequivocal identification of the event in biological samples. |
| US08309816B1 |
Soybean variety XBP38008
A novel soybean variety, designated XBP38008 is provided. Also provided are the seeds of soybean variety XBP38008, cells from soybean variety XBP38008, plants of soybean XBP38008, and plant parts of soybean variety XBP38008. Methods provided include producing a soybean plant by crossing soybean variety XBP38008 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XBP38008, methods for producing other soybean varieties or plant parts derived from soybean variety XBP38008, and methods of characterizing soybean variety XBP38008. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XBP38008 are further provided. |
| US08309813B2 |
Soybean variety A1024212
The invention relates to the soybean variety designated A1024212. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1024212. Also provided by the invention are tissue cultures of the soybean variety A1024212 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1024212 with itself or another soybean variety and plants produced by such methods. |
| US08309807B1 |
Soybean variety XB33B10
A novel soybean variety, designated XB33B10 is provided. Also provided are the seeds of soybean variety XB33B10, cells from soybean variety XB33B10, plants of soybean XB33B10, and plant parts of soybean variety XB33B10. Methods provided include producing a soybean plant by crossing soybean variety XB33B10 with another soybean plant, methods for introgressing a transgenic, mutant trait, and/or native trait into soybean variety XB33B10, methods for producing other soybean varieties or plant parts derived from soybean variety XB33B10. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB33B10 are further provided. |
| US08309805B1 |
Soybean variety XBP40005
A novel soybean variety, designated XBP40005 is provided. Also provided are the seeds of soybean variety XBP40005, cells from soybean variety XBP40005, plants of soybean XBP40005, and plant parts of soybean variety XBP40005. Methods provided include producing a soybean plant by crossing soybean variety XBP40005 with another soybean plant, methods for introgressing a transgenic, mutant trait, and/or native trait into soybean variety XBP40005, methods for producing other soybean varieties or plant parts derived from soybean variety XBP40005. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XBP40005 are further provided. |
| US08309797B2 |
Lettuce named ICE 15454
A novel lettuce cultivar, designated ICE 15454, is disclosed. The invention relates to the seeds of lettuce cultivar ICE 15454, to the plants of lettuce line ICE 15454 and to methods for producing a lettuce plant by crossing the cultivar ICE 15454 with itself or another lettuce line. The invention further relates to methods for producing a lettuce plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other lettuce lines derived from the cultivar ICE 15454. |
| US08309784B2 |
Method for confining a substance by vitrification
The present invention relates to a process for the manufacture of a glass frit for the containment by vitrification of a material comprising at least one oxidizable or reducible chemical species, and also to a process for the containment of said material by vitrification. The process for the manufacture of the glass frit comprises a step of incorporating into a raw glass frit at least one redox couple, the nature and the amount of which make it possible to maintain said at least one chemical species in its oxidized or reduced state. The containment process comprises mixing and hot melting the resulting glass frit and the material to be contained. The present invention makes it possible to optimize the containment of pollutants such as radionucleides, metals and metalloids. The material may be nuclear waste or a material derived from the incineration of household refuse. |
| US08309781B2 |
Process for the production of light olefins from ethanol in the presence of a macroporous catalyst that comes in the form of balls
A process for the production of C3-C6 light olefins from ethanol is described, and said process comprises at least the passage of a feedstock that contains ethanol into at least one reaction unit that is provided with at least one catalyst that comes in the form of spherical balls with a diameter of between 1 and 3 mm, each of said spherical balls comprising at least one zeolite and at least one alumina-based substrate and having a pore distribution such that the macropore volume that is measured by mercury porosimetry is between 0.10 and 0.20 ml/g and the mesopore volume that is measured by mercury porosimetry is between 0.25 and 0.35 ml/g. |
| US08309775B2 |
Method of preparing iodinated aromatic compounds
The present invention relates to a method of preparing iodinated aromatic compounds, and more preferably a method of preparing iodinated aromatic compounds comprising a step of iodinating a react ant including an aromatic compound, a di-iodo aromatic compound or water, and iodine (I2) in the presence of a zeolite catalyst and oxygen. The method of the present invention has an advantage that by iodination of a reactant including the aromatic compound, and the di˜ iodo aromatic compound or water in the presence of the zeolite catalyst and oxygen, the temperature of the iodinating reactor can be controlled reliably and constantly, thereby resulting in improved productivity per unit weight of catalyst and inhibition of a side reaction in accordance with suppression of producing impurities. In addition, the productivity of the iodinated aromatic compound, preferably the di-iodo aromatic compound, more preferably a p-di-iodo aromatic compound can be improved, and thus can be widely used in the preparation of a di-iodo aromatic compound such as a p-di-iodo aromatic compound. |
| US08309772B2 |
Tunable catalyst gas phase hydrogenation of carboxylic acids
A process for selective formation of ethanol from acetic acid includes contacting a feed stream containing acetic acid and hydrogen at an elevated temperature with catalyst comprising platinum and tin on a high surface area silica promoted with calcium metasilicate. Selectivities to ethanol of over 85% are achieved at 280° C. with catalyst life in the hundreds of hours. |
| US08309771B2 |
Two-stage, gas phase process for the manufacture of alkylene glycol
A two-stage, gas phase process for manufacturing alkylene glycol (e.g., ethylene glycol) from an alkene (e.g., ethylene), oxygen and water, the process comprising the steps of: (A) Contacting under gas phase, oxidation conditions gaseous alkene and oxygen over a heterogeneous oxidation catalyst to produce a gaseous oxidation product comprising alkylene oxide, water and unreacted alkene; (B) Contacting under gas phase, hydrolysis conditions the gaseous oxidation product of (A) with added water over a heterogeneous hydrolysis catalyst to produce a gaseous alkylene glycol and unreacted alkene; and (C) Recycling the unreacted alkene of (B) to (A). The hydrolysis catalyst is selected from the group consisting of hydrotalcites, metal-loaded zeolites, phosphates, and metal-loaded ion-exchanged molecular sieves. The process improves over the conventional two-stage process by the elimination of steps and equipment to recover and refine alkylene oxide, the use of less water in the hydrolysis reaction, and the elimination of the entire evaporation train used in the recovery of alkylene glycol. |
| US08309765B2 |
Process for manufacture of high purity D-(−)-N,N-diethyl-2-(α-naphthoxy) propionamide
According to one aspect of the present invention there is provided a substantially high purity D-(−)-N,N-diethyl-2-(α-naphthoxy)propionamide and a process for the manufacture of substantially higher purity D-(−)-N,N-diethyl-2-(α-naphthoxy)propionamide having chemical purity near about or above 95%, and chiral purity near about or more than 97%. According to another aspect of the invention is to provide an agrochemical compositions containing highly pure optically active D-(−)-N,N-diethyl-2-(α-naphthoxy)propionamide. |
| US08309764B2 |
Colchicine solid-state forms; methods of making; and methods of use thereof
Disclosed are new colchicine solid-state forms, methods of preparing the solid-state forms, as well as formulations prepared therefrom and uses thereof. |
| US08309760B2 |
Process for purification of aryl carboxylic acids
Disclosed herein is a process for purifying aryl carboxylic acids, in particular terephthalic acid, wherein the impure acid is dissolved or dispersed in an ionic liquid and a non-solvent is added to precipitate the purified acid. The present disclosure further relates to compositions comprising terephthalic acid and one or more ionic liquids. |
| US08309758B2 |
Allyl acetate purification
A process for purifying allyl acetate is disclosed. An acetoxylation mixture is distilled at elevated pressure to remove propylene and generate a first bottoms mixture comprising allyl acetate, acetic acid, acrolein, allyl diacetate, and 3-acetoxypropionaldehyde. The first bottoms mixture is flash vaporized, and the resulting vapor is contacted with a solid acidic catalyst under conditions effective to decompose allyl diacetate and 3-acetoxypropionaldehyde. The flashed product, which comprises allyl acetate, acetic acid, and acrolein, is then distilled to remove acrolein and generate a second bottoms mixture comprising allyl acetate and acetic acid. The second bottoms mixture can be used to manufacture allyl alcohol. |
| US08309753B2 |
Method for producing optically active cyanohydrin compound
A method of producing an optically active cyanohydrin compound represented by formula (3), which includes reacting an aldehyde compound represented by formula (2) with hydrogen cyanide in the presence of a silyl compound and an asymmetric complex which is obtained by reacting an optically active pyridine compound represented by formula (1) with an aluminum halide, and wherein Q1, Q2, R1 and R2 are defined in the specification. |
| US08309750B2 |
Process for the preparation of a diaryl carbonate
The invention relates to a process for the preparation of a diaryl carbonate, which comprises: (i) contacting an aromatic non-hydroxy compound with a carboxylic acid of formula HOC(═O)R1 (I), wherein R1 is a hydrocarbyl group, and with an oxygen containing gas in the presence of a catalyst, resulting in water and an aromatic carboxylic acid ester of formula R2OC(═O)R1 (II), wherein R2 is an aryl group originating from the aromatic non-hydroxy compound; and (ii) contacting the aromatic carboxylic acid ester of formula (II) from step (i) with a dialkyl carbonate of formula R3OC(═O)OR4 (III), wherein R3 and R4 are the same or different and are alkyl groups, in the presence of a catalyst, resulting in a diaryl carbonate of formula R2OC(═O)OR2 (IV) and an alkyl carboxylic acid ester of formula R5OC(═O)R1 (V), wherein R5 is R3 or R4. |
| US08309748B2 |
Half-metallocene compounds and catalyst compositions
The present invention provides polymerization catalyst compositions employing half-metallocene compounds with a heteroatom-containing ligand bound to the transition metal. Methods for making these hybrid metallocene compounds and for using such compounds in catalyst compositions for the polymerization of olefins also are provided. |
| US08309743B2 |
Compound comprising triarylamine moieties and a condensed ring moiety, and the production method thereof
The present invention provides a compound having absorbing and luminescence wavelengths at relatively longer wavelength side of the visible area, and having thermal stability, which acts as a dye and/or a luminescence material and has practical utility therefor, and a production method thereof. The above subject of the present invention can be solved by a compound represented by general formula I: R1—X—R2, wherein R1 and R2 each independently represents, for example, an N,N-diaryl-4-aminophenyl group, and X is one condensed ring group selected from the group consisting of following formulae X-1 to X-3: |
| US08309739B2 |
Chemical compounds
The use of a compound of formula I wherein X is (i), (ii) or (iii) Y is O, S(O)m, NR3, CR5R6, CR5R6—CR7R8, O—CR7R8, S(O)m—CR7R8, NR3—CR7R8, CR5R6—O, CR5R6—S(O)m, CR5R6—NR3, SO2—NR3, NR3—SO2, NR3—O or O—NR3; m is 0, 1, or 2; the ring (T) is a 5- or 6-membered aromatic or heteroaromatic ring; R1 to R10 are specified organic groups and n and is 0, 1, 2, 3 or 4; or salts or N-oxides thereof or compositions containing them in controlling insects, acarines, nematodes or molluscs. Novel compounds are also provided. |
| US08309734B2 |
Substituted pyridines as GPBAR1 agonists
This invention relates to novel phenyl amide or pyridyl amide derivatives of the formula wherein A1, A2, B1, B2 and R1 to R11 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are GPBAR1 agonists and can be used as medicaments for the treatment of diseases such as type II diabetes. |
| US08309728B2 |
Naphthalenetetracarboxylic acid derivatives and their use as semiconductors
The present invention relates to naphthalenetetracarboxylic acid derivates, to a process for their preparation and to their use, especially as an n-type semiconductor. |
| US08309718B2 |
4-pyrazolyl-N-arylpyrimidin-2-amines and 4-pyrazolyl-N-heteroarylpyrimidin-2-amines as janus kinase inhibitors
The present invention provides substituted bicyclic heteroaryl compounds, including, for example, 4-pyrazolyl-N-arylpyrimidin-2-amines and 4-pyrazolyl-N-heteroarylpyrimidin-2-amines that modulate the activity of kinases and are useful in the treatment of diseases related to activity of kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases. |
| US08309716B2 |
Pyrrolo[2,3-d]pyrimidine derivatives: their intermediates and synthesis
This invention relates to methods and intermediates useful for the synthesis of pyrrolo[2,3-d]pyrimidine compounds. Specifically novel synthetic methods and intermediates for the synthesis of 3-{(3R,4R)-4-methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amino}-piperidin-1-yl)-3-oxo-propionitrile and its corresponding citrate salt are disclosed. |
| US08309713B2 |
Process for the preparation of 6-α,9-α-difluoro-17-α-((2-furanylcarbonyl)oxy)-11-β-hydroxy-16-α-methy1-3-oxo-androsta-1,4-diene-17-β- -carbothioic acid S-fluoromethyl
A novel process for preparing a compound of formula (I) which comprises converting a compound of formula (II) to a compound of formula (I) via a compound of formula (III), or a salt thereof, without isolating any intermediates. |
| US08309712B2 |
Industrial process for the preparation of 17-hydroxy-6beta,7beta;15beta, 16beta-bismethylene-3-oxo-17alpha-pregn-4-ene-21-carboxylic acid y-lactone and key intermediates for this process
The invention relates to an industrial process for the preparation of 17-hydroxy-6β,7β;15β,16β-bismethylene-3-oxo-17α-pregn-4-ene-21-carboxylic acid γ-lactone of formula (I), and to the key-intermediates for this process. |
| US08309711B2 |
Filtration of corn starch followed by washing and collection of the resultant corn starch cake
The method of forming a filter cake from a slurry comprising the steps of feeding the slurry into a filter housing, wherein the filter housing includes a plurality of vertical filter elements; pressing the slurry into the filter housing against the filter elements resulting in i) a filtrate passing through the filter elements and exiting out an exhaust port of the filter housing; ii) forming a solid cake on the filter elements; feeding a wash liquid into the filter housing while draining out the slurry by opening the slurry drain valve; closing the slurry drain valve and then continually feeding wash liquid through the cake and into the filter tube of the filter housing; stopping the feed of wash liquid; introducing a gas into the filter housing and draining out the wash liquid by opening a bottom drain valve; stopping the gas flow and opening a drain to exit most of the gas and remaining wash liquid; opening the bottom cake discharge valve; and back pulsing by a gas to break and to release the filter cake from the filter elements of the filter housing. |
| US08309709B2 |
Method of preparing a separation matrix
The present invention relates to a method of preparing an insoluble separation matrix, which method comprises salt-treatment of a polysaccharide gel followed by cross-linking of the polysaccharide polymers. In one embodiment, the method comprises providing an aqueous solution of a gelatable native polysaccharide; lowering the temperature of the polysaccharide solution to a value below its gelling point; salt-treatment by adding at least one salt to the resulting polysaccharide; and cross-linking the salt-treated polysaccharide. The polysaccharide may be prepared e.g. into particles, membranes or monoliths. |
| US08309708B2 |
Crystalline sulphated cellulose II and its production from sulphuric acid hydrolysis of cellulose
A method for producing crystalline sulphated cellulose II materials with relatively low degree of polymerization from spent liquors of sulphuric acid (H2SO4) hydrolysis of cellulose has been discovered. The method involves: 1) separating the spent liquors from the hydrolysed, acid-insoluble, cellulose I materials by dilution from, for example, a 64% H2SO4 hydrolysis medium to a residual sulphuric acid concentration of 10-50% with 0-40% H2SO4, followed by settling (or centrifuging) and decanting; 2) adding the diluted spent liquors to water or heating the diluted spent liquors at 30-80° C. for ≦48 h; and 3) recovering the recrystallized sulphated cellulose II materials with relatively low degree of polymerization either by filtration and washing or by washing and freeze drying. The method can be used to concurrently produce both crystalline, sulphated cellulose I and the crystalline, sulphated cellulose II materials. |
| US08309707B2 |
RNA synthesis-phosphoramidites for synthetic RNA in the reverse direction, and application in convenient introduction of ligands, chromophores and modifications of synthetic RNA at the 3′-end
Novel technology for RNA synthesis in the reverse direction, involving a new class of products, 3′-DMT-5’-CE ribonucleoside phosphoramidites and 3′-DMT-5’-succinyl ribonucleoside solid supports, with per step coupling efficiency surpassing 99% in the RNA synthesis. This leads to high purity RNA. Examples of a large number of 20-21 mers and a few examples of long chain oligonucleotides are demonstrated. The data indicates dramatic improvement in coupling efficiency per step during oligonucleotide synthesis using the reverse RNA monomers (5′→′ direction) as compared to 3′-CE ribonucleoside phosphoramidites used in the conventional method of RNA synthesis (3′→5′ direction). The new process requires shorter coupling cycle time, approx. 4 minutes as compared to approx. 10 minutes using conventional RNA synthesis method (3′→5′ direction). Furthermore, almost complete absence of M+1 impurities in the reverse RNA synthesis methodology were observed, even when the last phosphoramidite was a macromolecule. The process resulted in very high purity 3′-modified oligonucleotides after HPLC purification. As a result of high purity of synthesized RNA and clean introduction of various 3′-end modified RNA requiring long chain ligands, chromophores, fluorophores and quenchers, this method of RNA synthesis is expected to be a very useful method of choice for therapeutic grade RNA. The novel phosphoramidites of this invention, Rev-A-n-bz, Rev-C-n-bz, Rev-C-n-ac, Rev-G-n-ac and Rev-rU show HPLC purity greater than 98% and 31P NMR purity greater than 99.5%. |
| US08309706B2 |
Methods of synthesizing oligonucleotides using carbonate protecting groups and alpha-effect nucleophile deprotection
The invention provides methods for synthesizing oligonucleotides using nucleoside monomers having carbonate protected hydroxyl groups that are deprotected with α-effect nucleophiles. The α-effect nucleophile irreversibly cleave the carbonate protecting groups while simultaneously oxidizing the internucleotide phosphite triester linkage to a phosphodiester linkage. The procedure may be carried out in aqueous solution at neutral to mildly basic pH. The method eliminates the need for separate deprotection and oxidation steps, and, since the use of acid to remove protecting groups is unnecessary, acid-induced depurination is avoided. Fluorescent or other readily detectable carbonate protecting groups can be used, enabling monitoring of individual reaction steps during oligonucleotide synthesis. The invention is particularly useful in the highly parallel, microscale synthesis of oligonucleotides. |
| US08309701B2 |
Variants of human taste receptor genes
Identified herein are different forms of bitter receptor genes that occur in different humans. These alleles are generated by numerous coding single nucleotide polymorphisms (cSNP's) that occur within the members of the T2R gene family. Some SNP's cause amino acid substitutions, while others introduce chain termination codons, rendering the allele non-functional. Differences in these genes are believed to have a large effect on those individuals' sense of bitter taste, such that these individuals perceive the taste of bitter substances differently than the rest of the population. The ability to assay this allelic information is useful in the development of flavorings and flavor enhancers, as it can be used to define large groups and populations who perceive bitter tastes differently. This in turn allows the taste preferences of these groups to be addressed at the molecular level for the first time. |
| US08309699B2 |
Methods for determining the presence or absence of elite event RF-BN1 in Brassica plant material
This invention relates to transgenic winter oilseed rape (WOSR) plants, plant material and seeds, harboring a specific transformation event. It pertains to winter oilseed rape plants, more particularly to a pair of winter oilseed rape plants, which is particularly suited for the production of hybrid seed. More specifically, one plant is characterized by being male-sterile, due to the presence in its genome of a male sterility gene, while the other is characterized by carrying a fertility-restorer gene, capable of preventing the activity of the male-sterility gene. The invention further provides a method for producing hybrid seed, a process for producing a transgenic WOSR plant oil or plant, and a method to identify a transgenic plant, cell or tissue. A kit for identifying the transgenic plants comparing the elite event of the present invention is also described. The WOSR plants of the invention combine the ability to form hybrid seeds with optimal overall agronomic performance, genetic stability and adaptability to different generic backgrounds. |
| US08309698B2 |
Expression vector suitable for expression of a coding sequence for gene therapy
Provided is an expression vector for gene therapy having a novel combination of transcriptional regulatory elements, including a promoter, an enhancer, an intron, an untranslated region (UTR) and a locus control region (LCR). The expression vector enables sustained expression of a liver tissue-specific gene, and thus, can be effectively used for treating thrombosis, hemophilia, liver cancer, etc. |
| US08309695B2 |
Marking reagents bearing diazo and nitro functions, methods for the synthesis of such reagents and methods for detecting biological molecules
The present invention relates to a labeling reagent of formula: in which: R1 represents at least one detectable label, L and A are each a linker arm, n is an integer equal to 1, and u is an integer between 0 and 2. The present invention also describes a method of synthesizing said markers and also applications for the labeling of biological molecules, more particularly nucleic acids, with a labeling reagent bearing diazo and nitro functions. The invention is particularly suitable for use in the diagnostics field. |
| US8309694B2 |
RECOVERY OF LIGNIN AND WATER SOLUBLE SUGARS FROM PLANT MATERIALS
In one aspect, a process for treating woody plant material is provided, the process involving contacting the plant material with a continuous flow of an aqueous ethanol solution at elevated temperature and pressure under conditions that promote extraction of ethanol-soluble lignin from the plant material and retention of hemicellulose sugars, xylose and cellulose in the treated plant material solids. In another aspect, a process for extracting hemicellulose sugars from lignin-depleted plant material solids is provided, the process involving contacting lignin-depleted plant material with water at elevated temperature and pressure under conditions that promote extraction of hemicellulose sugars from the plant material; and recovering hemicellulose sugars from the liquid mixture. |
| US08309691B2 |
Chlamydomonas intraflagellar transport 88 (IFT-88)
The invention relates to various intraflagellar transport (IFT) polypeptides and the nucleic acids that encode them. The new IFT particle polypeptides and nucleic acids can be used in a variety of diagnostic, screening, and therapeutic methods. |
| US08309683B2 |
Thermal crystallization of a molten polyester polymer in a fluid
A process for crystallizing a polyester polymer by introducing a molten polyester polymer, such as a polyethylene terephthalate polymer, into a liquid medium at a liquid medium temperature greater than the Tg of the polyester polymer, such as at a temperature ranging from 100° C. to 190° C., and allowing the molten polyester polymer to reside in the liquid medium for a time sufficient to crystallize the polymer under a pressure equal to or greater than the vapor pressure of the liquid medium. A process flow, underwater cutting process, crystallization in a pipe, and a separator are also described. |
| US08309676B2 |
Formaldehyde free binders
New polyols; oligomers, and polymers made from the polyols; and binders made from the new polyols, oligomers, or polymers that can be used in binders, where the binders typically include one or more polyols, and a polyfunctional acid or a polyfunctional nitrile. |
| US08309675B2 |
Highly acetalized, coarse-grained polyvinyl acetoacetals
The invention relates to highly acetalized, coarse-grained polyvinyl acetals with a degree of acetalization of >80 mol % and an average grain size of ≧100 μm obtainable by acetalization of partially or fully hydrolyzed polyvinyl esters with a degree of hydrolysis of ≧70 mol % with acetaldehyde, characterized by the fact that the acetalization is started at a temperature T1 of 0° C.≦T1≦+20° C. and is then continued at a temperature T2 of >+40° C., wherein the temperature T2 is held for a time period of 0.05 to 4 hours and the acetalization is performed in a closed reactor. |
| US08309674B2 |
Cardanol based dimers and uses therefor
Cardanol based dimers are provided. The cardanol dimers are formed by hydrosylylation with silanes. Cardanol based dimers may be further reacted to form epoxy curing agents and epoxies which can be used as anti-fouling coatings on ship hulls and marine structures. The cardanol dimers may also be used to produce friction particles or phenolic resins. Methods of synthesizing the cardanol based dimers, the epoxy curing agents and the epoxies are also provided. |
| US08309673B2 |
Polyether siloxane-containing alkoxylation products by direct alkoxylation of organomodified α,ω-dihydroxysiloxanes over double metal cyanide (DMC) catalysts, and also process for producing them
Novel silicone polyethers by alkoxylating polymerization of epoxide monomers with (poly)organosiloxanes starting from an α,ω-dihydroxysiloxane as starter by means of DMC catalysis and process for preparing them. |
| US08309672B2 |
Soluble conjugated polymers
Methods, compositions and articles of manufacture involving soluble conjugated polymers are provided. The conjugated polymers have a sufficient density of polar substituents to render them soluble in a polar medium, for example water and/or methanol. The conjugated polymer may desirably comprise monomers which alter its conductivity properties. In some embodiments, the inventors have provided cationic conjugated polymers (CCPs) comprising both solubilizing groups and conductive groups, resulting in conductive conjugated polymers soluble in polar media. The different solubility properties of these polymers allow their deposition in solution in multilayer formats with other conjugated polymers. Also provided are articles of manufacture comprising multiple layers of conjugated polymers having differing solubility characteristics. Embodiments of the invention are described further herein. |
| US08309667B2 |
Water-soluble copolymer having alkyl-modified carboxyl groups
A water-soluble copolymer having alkyl-modified carboxyl groups which is able to produce a neutralized viscous liquid in which although its viscosity is very low when no electrolyte exists, the viscosity greatly increases when electrolytes are added, which has a high viscosity and a high transmittance and which has moist textures without stickiness even in the presence of a relatively high concentration of electrolytes, and a thickening agent comprising the same. |
| US08309661B2 |
Block coordination copolymers
The present invention provides compositions of crystalline coordination copolymers wherein multiple organic molecules are assembled to produce porous framework materials with layered or core-shell structures. These materials are synthesized by sequential growth techniques such as the seed growth technique. In addition, the invention provides a simple procedure for controlling functionality. |
| US08309659B2 |
Filled polyolefin compositions
Filled polyolefin compositions comprising: A) from 20% to 80% by weight of a polypropylene component; B) from 20% to 80% by weight of a filler; wherein the percentages of A) and B) are referred to the sum of A) and B), and A) is selected from the following compositions: a) a polypropylene composition containing from 20% to 80% by weight of a polypropylene fraction AI) having a Melt Flow Rate value of 500 g/10 min. or more, and from 20% to 80% by weight of a polypropylene fraction AII) having a Melt Flow Rate value of from 0.1 to 30 g/10 min., the said percentages of AI) and AII) being referred to the sum of AI) and AII); or b) a polypropylene composition containing from 15% to 72% by weight of a polypropylene fraction AI) having a Melt Flow Rate value of 500 g/10 min. or more, from 15% to 70% by weight of a polypropylene fraction AII) having a Melt Flow Rate value of from 0.1 to 30 g/10 min. and from 0.5% to 15% by weight of a compatibilizer Q), the said percentages of AI), AII) and Q) being referred to the sum of AI), AII) and Q). |
| US08309658B2 |
Adhesive composition, circuit connecting material, connecting structure for circuit member, and semiconductor device
The adhesive composition of the invention comprises a thermoplastic resin, a radical polymerizing compound, a radical polymerization initiator and a radical polymerization regulator. According to the present invention it is possible to provide an adhesive composition, a circuit connecting material, a connection structure for a circuit member and a semiconductor device whereby curing treatment can be carried out with sufficient speed at low temperature, curing treatment can be carried out with a wide process margin, and adequately stable adhesive strength can be obtained. |
| US08309654B2 |
Method of producing particle-shape water-absorbing resin material
A method of producing a particle-shape water-absorbing resin material is realized. With this method, it is possible to prevent deterioration of properties of the particle-shape water-absorbing resin material, and reduces damages onto surfaces thereof. This method is arranged such that (a) water-absorbing resin particles are surface-treated by using a crossing agent so that surfaces of the particles are cross-linked, (b) an additive for giving a function to the particles is added to the particles, (c) and a step of mixing the particles and the additive is carried out in a step of performing particle-size regulating treatment for the particles which includes agglomerated particles. |
| US08309653B2 |
Ambient cure water-based coatings for writable-erasable surfaces
Water-based coatings having writable-erasable surfaces are provided. The coatings have many desirable attributes. For example, the coatings cure under ambient conditions, have low or no VOC emissions during and upon curing, and have reduced tendency to form ghost images, even after prolonged normal use. |
| US08309648B2 |
Silicone free defoamer for solvent based coatings
This disclosure relates to a silicone free defoamer for solvent based coatings, especially clear wood coatings preferably based on a graft copolymer of poly alkyl vinyl ether. The coating composition comprises a resin binder component and a defoamer formulation. |
| US08309646B2 |
Use of highly-branched polymers for producing polymer dispersions with improved freeze/thaw stability
The present invention relates to a method of producing polymer dispersions having improved freeze-thaw stability, by adding a highly branched polymer to said dispersions, and also to the use of highly branched polymers for this purpose. |
| US08309644B1 |
Methods of treating carbon fibers, fiber-reinforced resins, and methods of making the fiber-reinforced resins
A method of treating carbon fibers includes introducing a functional group to a carbon fiber surface, and reacting the functional group with a silane to incorporate a silanol moiety to the carbon fiber surface. The functional group is chosen from amine groups, carboxyl groups, hydroxyl groups, and/or carbonyl groups. Also disclosed herein are a fiber-reinforced resin and a method of making the same. |
| US08309643B2 |
Polyamide moulding compound and use thereof
The present invention relates to polyamide moulding compounds which have very low distortion with good mechanical properties. This is achieved by a combination of transparent polyamide with fibrous reinforcing materials and also particulate fillers. The moulding compounds according to the invention are used for the production of any moulded articles, semi-finished products or finished products. |
| US08309641B2 |
Curable fluoroelastomer compositions
Disclosed herein is a curable composition comprising a curable fluoroelastomer, a curative and an acid acceptor selected from the group consisting of a hydrous bismuth oxide nitrate compound and bismuth oxide. Cured articles made therefrom are resistant to volume swell in acids, coolant and in biofuel. |
| US08309637B2 |
Polyimide polyphenylsulfone blends with improved flame resistance
The present disclosure relates to a composition with improved flame resistance, to articles made from the composition, and to methods that include processing the composition. The composition can include from 15 to 85 percent by weight of a polyetherimide (PEI), from 15 to 85 percent by weight of a polyphenylsulfone (PPSU), a polyetherimide-siloxane copolymer in an amount up to 12 percent by weight, and from 0 to 0.30 percent by weight of a stabilizer. |
| US08309634B2 |
Polyvinylidene chloride compositions and their use in monofilament structures
The present invention includes a monofilament obtainable by extruding a composition comprising: (a) at least one vinylidene chloride polymer/methyl acrylate interpolymer having at most about 6 weight percent methyl acrylate mer units in the polymer; and (b) at least about three weight percent total plasticizer, of which about 0.5 weight percent based on total composition weight is an epoxy plasticizer or combination thereof through a die such that monofilament is formed. Optionally, and preferably in extruders wherein the composition of (a) and (b) exhibits less uniformity in extrusion than is desired, at least one methacrylic polymer is also added. The invention also includes a process of extruding a composition of at least (a) and (b) to form a monofilament. |
| US08309632B2 |
Liquid crystalline epoxy nanocomposite material and application thereof
The invention provides an epoxy nanocomposite material for dental therapy, which can be applied to direct or indirect clinical restoration, dental core-post system, and dental brace etc. The epoxy nanocomposite filling material provided by the invention can be polymerized with various curing agents to form the polymer with low shrinkage. |
| US08309626B2 |
Microbiocidal coatings
There is provided a coating composition comprising (a) one or more microbicide, (b) one or more soluble polymer comprising acrylamide as polymerized units, wherein said polymer has is non-anionic, and (c) solvent, wherein said polymer is dissolved in said solvent. Also provided is a method of coating a substrate with such a coating, and also provided is the resulting coated substrate. |
| US08309608B2 |
Use of eNOS transcription enhancers in the cell therapy of ischemic heart diseases
The present invention relates to the use of compounds which enhance the transcription of endothelial nitric oxide synthase (eNOS) for treating stem and progenitor cells in the cell therapy of patients with ischemic heart diseases such as coronary heart disease or ischemic cardiomyopathy. Treatment of such cells which are isolated from bone marrow, for example, with an eNOS transcription enhancer prior to their administration improves their functional activity and ameliorates neovascularization of the heart and cardiac regeneration. |
| US08309605B2 |
Enhanced bimatoprost ophthalmic solution
A composition comprising from 0.005% to 0.02% bimatoprost by weight and from 100 ppm to 250 ppm benzalkonium chloride, wherein said composition is an aqueous liquid which is formulated for ophthalmic administration is disclosed herein.A method which is useful in treating glaucoma or ocular hypertension related thereto is also disclosed herein. |
| US08309603B2 |
SARMs and method of use thereof
This invention is directed to a feed composition and method of affecting the carcass composition by increasing the lean mass, reducing the fat mass, and/or reducing the percent fat mass comprising SARM compounds. |
| US08309599B2 |
Synthesis of FR901464 and analogs with antitumor activity
The present invention provides novel analogs of FR901464, as well as an improved methodology for preparing FR901464 and its analogs. These compounds display an anti-cancer activity and are candidates for therapies against a number of disease states associated with dysfunctional RNA splicing. |
| US08309597B2 |
1,1′-diadamantyl carboxylic acids, medicaments containing such compounds and their use
The present invention relates to compounds defined by formula (I) wherein the group R is defined as in claim 1, possessing valuable pharmacological activity. Particularly the compounds are inhibitors of 11β-hydroxysteroid dehydrogenase (HSD) 1 and thus are suitable for treatment and prevention of diseases which can be influenced by inhibition of this enzyme, such as metabolic diseases. |
| US08309590B2 |
Triazol compounds for treating biofilm formation
The present invention relates to the use of a Compound of formula I preferably 4-[3,5-bis(2-hydroxyphenyl)-[1,2,4]triazol-1-yl]benzoic acid or a pharmaceutically acceptable salt thereof for the preparation of a medicament for use in the treatment of biofilm formation, e.g. of P. aeruginosa, e.g. in cystic fibrosis patients. |
| US08309589B2 |
Fluorine-containing organosulfur compound and pesticidal composition comprising the same
There is provided a fluorine-containing organosulfur compound having an excellent controlling effect on arthropod pests represented by the formula (I): wherein m represents 0 or 1; n represents 0, 1 or 2; A represents an optionally substituted 5-membered aromatic heterocyclic group; R1 and R3 are independently represent an optionally substituted C1-C4 chain hydrocarbon group, —C(═G)R5, cyano, halogen or hydrogen; R2 and R4 independently represent an optionally substituted C1-C4 chain hydrocarbon group, halogen or hydrogen; Q represents a C1-C5 haloalkyl group containing at least one fluorine, or fluorine; G represents oxygen or sulfur; and R5 represents optionally substituted C1-C4 alkyl, hydroxyl, optionally substituted C1-C4 alkoxy, optionally substituted C3-C6 alkenyloxy, optionally substituted C3-C6 alkynyloxy, amino, optionally substituted C1-C4 alkylamino, optionally substituted di(C1-C4 alkyl)amino, C2-C5 cyclic amino or hydrogen. |
| US08309587B2 |
Piperidine and piperazine phenyl sulphonamides as modulators of ion channels
The present invention relates to piperidine and piperazine phenyl sulfonamides useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders, including for example the treatment of pain. |
| US08309581B2 |
Benzimidazole derivatives
The present invention relates to compounds of formula (I), as well as pharmaceutically acceptable salts thereof can be used in the form of pharmaceutical compositions, wherein A, B, R1, R2, R3, R4, R5, n, m and p have the significance defined herein. |
| US08309578B2 |
Bicyclic pyrazole and isoxazole derivatives as antitumor and antineurodegenerative agents
Bicyclic pyrazole and isoxazole derivatives of formula (I) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful in therapy in the treatment of diseases mediated by HSP90 protein, like cancer and neurodegenerative disorders. |
| US08309577B2 |
Quinuclidine compounds as α-7 nicotinic acetylcholine receptor ligands
The disclosure provides compounds of formula I, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic α7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders. |
| US08309575B2 |
Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
The invention provides novel quinolinone-carboxamide 5-HT4 receptor agonist compounds of Formula (I). The invention also provides pharmaceutical compositions comprising such compounds, the use such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds. Wherein; R1 is hydrogen, halo, hydroxy, C1-4 alkyl, or C1-4 alkoxy; R2 is C3-4 alkyl, or C3-6cycloalkyl; R3 is hydrogen or C1-3 alkyl: R4 is S(O)2R6 or C(O)R7; R5 is hydrogen, C1-3alkyl, C2-3 alkyl substituted with —OH or C1-3 alkoxy, or —CH2-pyrydyl; R6 is C1-3 alkyl; or R5 and R6 taken together from C3-4 alkylenyl; and R7 is hydrogen, C1-3alkyl, or pyrydyl; or pharmaceutically-acceptable salt or solvate or stereoisomer thereof. |
| US08309574B2 |
Nuclear transfer promoter for Rac protein and method of screening the same
A nuclear transfer promoter for Rac protein comprising an isoprenoid synthesis inhibitor and/or a geranylgeranyl transferase inhibitor such as an HMG-CoA synthase inhibitor, an HMG-CoA reductase inhibitor, an AMPK activator or a farnesyl pyrophosphoric acid synthase preparation; utilization thereof; a method therefor; a blood vessel remedy comprising the nuclear transfer promoter for Rac protein as the active ingredient; and a method of screening a blood vessel remedy which comprises assaying the ability of Rac protein to transfer into nucleus. |
| US08309569B2 |
Methods for treating diarrhea-associated irritable bowel syndrome
The present invention provides methods of treating diarrhea-associated irritable bowel syndrome (IBS-D) following rifaximin administration. |
| US08309567B2 |
Spiroindoline derivatives having insecticidal properties
An insecticidal compound of formula (I), wherein Y is a single bond, C═O, C═S or S(O)m where m is 0, 1 or 2; R1, R2, R3, R4, R8 A1, A2, A3, A4, B1, B2, B3 and B4 are specified organic groups or salts or N-oxides thereof; compositions containing them and their using in controlling insects, acarines, nematodes or molluscs. |
| US08309566B2 |
Pyrimidine-2-amine compounds and their use as inhibitors of JAK kinases
This invention is directed to compounds of formula (I): where n, m, Y, R1, R2, R3, R4 and R5 are disclosed herein, as isolated stereoisomers or mixtures thereof, or as pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising the compounds of formula (I); and methods of using the compounds and the pharmaceutical compositions in treating diseases or conditions associated with JAK2 activity. |
| US08309565B2 |
Phosphonate compounds
The present invention relates to phosphonate compounds, compositions containing them, processes for obtaining them, and their use for treating a variety of medical disorders, e.g., osteoporosis and other disorders of bone metabolism, cancer, viral infections, and the like. |
| US08309563B2 |
Quinazoline derivatives useful as anti-tumor medicament
he present invention has disclosed a compound of formula I and a pharmaceutically acceptable salt or a solvate thereof, wherein the substituents are as defined in the description. The invention has also disclosed a method for preparing the compound of formula I, the pharmaceutical compositions comprising the same and their uses in the preparation of an anti-tumor medicament. |
| US08309560B2 |
Methods and compositions for ameliorating the undesirable effects of chemotherapy
In one aspect, the present invention provides chemoprotectant compositions that each comprise at least two of the chemoprotectants disclosed herein. The chemoprotectant compositions of the invention are useful, for example, for ameliorating at least one adverse effect of chemotherapy. In another aspect, the present invention provides methods of ameliorating at least one adverse effect of chemotherapy, the methods each comprising the step of administering to a subject undergoing chemotherapy an amount of a chemoprotectant composition that is effective to ameliorate at least one adverse effect of the chemotherapy. |
| US08309556B2 |
Use of compounds derived from pyrimidinetrione as acetyl cholinesterase inhibitors, compositions containing said derivatives, and the uses thereof
The invention relates to the use of compounds derived from pyrimidinetrione of general formula (I) as acetyl cholinesterase (AChE) inhibitors. The invention also relates to the use of said compounds as insecticides, and to compositions containing the same. |
| US08309555B2 |
Compositions and methods for inducing cell dedifferentiation
The present invention provides 2,6-disubstituted purine compounds, compositions and methods for dedifferentiating lineage committed mammalian cells into stem cells. The present invention also provides methods of inducing dedifferentiation of lineage committed mammalian cells into stem cells, which can be further differentiated into various lineage committed cells. Methods of identifying additional 2,6-disubstituted purine compounds useful for inducing dedifferentiation of lineage committed cells into stem cells are also provided. |
| US08309551B2 |
Pyrazolopyridine, indazole, imidazopyridine, imidazopyrimidine, pyrazolopyrazine and pyrazolopyridine derivatives as stimulators of guanylate cyclase for cardiovascular disorders
The present application relates to novel azabicyclic compounds, processes for their preparation, their use alone or in combinations for the treatment and/or prevention of diseases, and their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular disorders. |
| US08309549B2 |
Compositions for modulating a kinase cascade and methods of use thereof
The invention relates to compositions comprising 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide and its mesylate and dihydrochloride salts. The invention provides an efficient process for the synthesis of 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide and its mesylate and dihydrochloride salts and methods for modulating one or more components of a kinase cascade using the compositions of the invention. The present invention also provides a novel polymorph of the mesylate salt of 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-N-benzylacetamide (Form A), characterized by a unique X-ray diffraction pattern and Differential Scanning Calorimetry profile, as well as a unique crystalline structure. |
| US08309547B2 |
Processes for the preparation of rivaroxaban and intermediates thereof
Provided are process for the preparation of (R)- and/or (S)-Rivaroxaban, and compounds which are intermediate compounds used in the processes for the preparation of (R)- and/or (S)-Rivaroxaban. |
| US08309545B2 |
Benzofuran potassium channel blockers and uses thereof
The present invention relates to compounds useful in the modulation of potassium channel activity in cells, in particular the activity of Kv1.3 channels found in T cells. The invention also relates to the use of these compounds in the treatment or prevention of autoimmune and inflammatory diseases, including multiple sclerosis, pharmaceutical compositions containing these compounds and methods for their preparation. |
| US08309542B2 |
Substituted pyrrolidine amides, the production thereof, and the use thereof as medications
The object of the present invention is novel substituted pyrrolidine amides of the general formula (I) in which D, L. E, G, J, M, L1, L2, R4, and R5 are defined as in the specification, the tautomers, enantiomers, diastereomers, mixtures, and salts thereof, particularly physiologically tolerated salts with inorganic or organic acids or bases having valuable properties. |
| US08309538B2 |
Capsaicinoid decontamination compositions and methods of use
A method for cleansing and treating skin exposed to a capsaicin or derivative thereof so as to inhibit capsaicin reactivation includes: providing a subject having exposure to capsaicin, oleoresin capsicum, or other capsaicinoid derivative; cleansing capsaicin, oleoresin capsicum, or other capsaicinoid derivative from skin of the subject with a cleansing composition having: a carrier; a surfactant and/or detergent; a chelating agent; and salicylic acid, acetylsalicylic acid, or ibuprofen; and treating the skin of the subject with a therapeutic composition so as to inhibit reactivation of effects of capsaicin, oleoresin capsicum, or other capsaicinoid derivative exposure, the therapeutic composition having: a carrier; aloe; a thickening agent; and salicylic acid, acetylsalicylic acid, or ibuprofen. |
| US08309532B2 |
Therapeutic uses of inhibitors of RTP801
The present invention provides novel molecules, compositions, methods and uses for treating microvascular disorders, eye diseases and respiratory conditions based upon inhibition of the RTP801 gene and/or protein. |
| US08309530B2 |
Compositions and methods for modulating ghrelin-mediated conditions
In certain aspects, the preproghrelin gene, but not the ghrelin receptor (GHS-R1a) is required for normal integration of thermoregulation and sleep in mice. Particular aspects provide methods for modulation of thermoregulation and other ghrelin-mediated conditions (e.g., reduction of appetite or food intake, reduction of body weight or treatment of obesity, reduction of body temperature or induction of hypothermia, etc.), comprising administration of an inhibitor of ghrelin expression, and including, e.g., siRNA inhibition for treatment of obesity and for modulation of thermoregulation (e.g., induction of hypothermia in surgical settings benefiting from same). Additionally provided are methods for reducing body temperature or induction of hypothermia, comprising administration to a mammalian subject in need thereof an amount of an anti-obestatin antibody agent sufficient to reduce body temperature or induce hypothermia. Further methods comprise administration of a ghrelin peptide antagonist. |
| US08309526B2 |
Nitrated lipids and methods of making and using thereof
Described herein are nitrated lipids and methods of making and using the nitrated lipids. |
| US08309524B2 |
Chimeric RGMa polypeptides
This invention features methods and compositions useful for treating and diseases caused by a dysregulation of the BMP/GDF branch of the TGF-β signaling pathway. Also disclosed are methods for identifying compounds useful for such therapy. |
| US08309523B2 |
Inhibitors of MALT1 proteolytic activity and uses thereof
The present invention relates to inhibitors of MALT1 proteolytic and/or autoproteolytic activity. More specifically, it relates to compounds such as, but not limited to peptide derivates such as Z-LSSR-CHO (see SEQ ID NO:1), Z-LSSR-CMK (see SEQ ID NO:1), Z-GASR-CHO (see SEQ ID NO:2), and Z-GASR-CMK (see SEQ ID NO:2), and small compounds such as 5-{[5-(3-chloro-4-methylphenyl)-2-furyl]methylene}-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione and variants thereof, and the use of those compounds for the preparation of a medicament. The invention relates further to a method to screen for inhibitors of the MALT1 proteolytic and/or autoproteolytic activity. |
| US08309514B2 |
Peptide nucleic acid based guanidinium compounds
Disclosed herein are transmembrane transporter compounds containing guanidinium groups to enhance transport across biomembranes. Therapeutic and other biologically active moieties may be attached to the compounds. The transmembrane transporter compounds may include peptide nucleic acid monomer units. |
| US08309504B2 |
Light duty liquid cleaning compositions and methods of manufacture and use thereof
The invention encompasses liquid cleaning compositions, for example, dish washing liquids, and methods of their manufacture and use, which possess enhanced cleaning ability. The cleaning compositions of the invention include acidic light duty liquid cleaning compositions with low toxicity and antibacterial efficacy on surfaces, for example, hard surfaces. |
| US08309503B2 |
Release agent for composite panel
The present invention is directed to a pMDI release agent that is simple to manufacture and use, provides release between the board and the metal surfaces, allows for production of OSB at high temperature, without causing excessive press buildup and improves the board physical properties and shortens press time. The release agent composition for use with a pMDI adhesive comprises a mixture of: (a) a sodium salt of a fatty acid having at least 8 carbon atoms, and (b) a sodium salt of a phosphate ester having 8-12 carbon atoms. |
| US08309502B2 |
Compositions and methods for removing organic substances
Compositions and methods useful for the removal of organic substances from substrates, for example, electronic device substrates such as microelectronic wafers or flat panel displays, are provided. A method is presented which applies a minimum volume of the composition as a coating to the inorganic substrate whereby sufficient heat is added and immediately rinsed with water to achieve complete removal. These compositions and methods are particularly suitable for removing and completely dissolving photoresists of the positive and negative varieties as well as thermoset polymers from electronic devices. |
| US08309501B2 |
Ethylene-based copolymers, lubricating oil compositions containing the same, and methods for making them
Provided are ethylene-based copolymers, methods of preparing the same, lubricating oil compositions including the same, methods for preparing such lubricating oil compositions, and end uses for such ethylene-based copolymers and lubricating oil compositions. The ethylene-based copolymers may include less than about 80 wt. % of units derived from ethylene and one or more alpha-olefin comonomers having 3 to 20 carbon atoms. The ethylene-based copolymers have a melting peak (Tm), as measured by DSC, of 80° C. or less, and a polydispersity index of about 2.8 or less. In some embodiments, the ethylene-based copolymers have an intramolecular composition distribution of about 50 wt. % or less and/or an intermolecular composition distribution of about 50 wt. % or less. |
| US08309495B2 |
Method for the production of a superconducting electrical conductor, and a superconducting conductor
A method is specified for production of a superconducting electrical conductor which has a ceramic material as the superconducting material. A metal ribbon is formed around a multiplicity of flat strips of a mount which is coated with the superconducting ceramic material, running longitudinally to form a tube having a slot which runs in the longitudinal direction, and whose edges which rest on one another on the slot are welded to one another The tube which is closed by the welding process is then reduced to a diameter which corresponds approximately to the envelopes of all the strips which are located in the tube. |
| US08309494B2 |
Iron-based superconducting substance
The invention provides an iron-based superconducting substance capable of bringing about superconductivity without using any toxic elements. The iron-based superconducting substance includes a composition wherein an FeTe alloy is doped with sulfur in such a way as to satisfy the following formula 1. Fe(Te1-xSx)y where 0 |
| US08309489B2 |
Thermally stable nanoparticles on supports
An inverse micelle-based method for forming nanoparticles on supports includes dissolving a polymeric material in a solvent to provide a micelle solution. A nanoparticle source is dissolved in the micelle solution. A plurality of micelles having a nanoparticle in their core and an outer polymeric coating layer are formed in the micelle solution. The micelles are applied to a support. The polymeric coating layer is then removed from the micelles to expose the nanoparticles. A supported catalyst includes a nanocrystalline powder, thin film, or single crystal support. Metal nanoparticles having a median size from 0.5 nm to 25 nm, a size distribution having a standard deviation ≦0.1 of their median size are on or embedded in the support. The plurality of metal nanoparticles are dispersed and in a periodic arrangement. The metal nanoparticles maintain their periodic arrangement and size distribution following heat treatments of at least 1,000° C. |
| US08309488B2 |
Exhaust gas purifying catalyst
An exhaust gas purifying catalyst includes a catalyst substrate and a catalyst coating layer containing a noble metal and a refractory inorganic oxide. The catalyst coating layer includes an upstream portion located upstream and a downstream portion located downstream in a flow direction of an exhaust gas. The upstream portion has a layered structure including an upstream portion inside layer containing a cerium-zirconium composite oxide in which a relative proportion of CeO2 is 50 to 95 wt %, as the refractory inorganic oxide and an upstream portion outside layer containing a cerium-zirconium composite oxide in which a relative proportion of ZrO2 is 50 to 95 wt %, as the refractory inorganic oxide. The upstream portion outside layer and the downstream portion contain Rh as the noble metal, and an amount of Rh contained in the upstream portion outside layer is larger than an amount of Rh contained in the downstream portion. |
| US08309487B2 |
Exhaust gas purifying catalyst and method for producing the same
An exhaust gas purifying catalyst (1) is composed of: a noble metal (2); a first compound (3); and a second compound (4). The noble metal (2) is supported on the first compound (3). The exhaust gas purifying catalyst (1) includes units having a structure in which the first compound (3) supporting the noble metal (2) is surrounded by the second compound (4), and the first compound (3) supporting the noble metal (2) is isolated from one another by the second compound (4). The noble metal (2) is one or more selected from [Pt, Pd and Rh], the first compound (3) contains Ti as a main component, and the second compound (4) contains, as a main component, one or more selected from [Al and Si]. |
| US08309486B2 |
Composite solid acid catalyst, preparing process and application in the alkylation
The present invention provides a composite solid acid catalyst consisting of from 50%-80% by weight of a porous inorganic support, from 15% to 48% by weight of a heteropoly compound loaded thereon, and from 2% to 6% by weight of an inorganic acid. The present invention further provides a process for preparing said composite solid acid catalyst and a process for conducting an alkylation reaction by using such catalyst. The composite solid acid catalyst of the present invention has the acid sites type of Brönsted acid and has an acid sites density of not less than 1.4×10−3 mol H+/g. Moreover, said composite solid acid catalyst has the homogeneous acid strength distribution, and is a solid acid catalyst having excellent performances. |
| US08309476B2 |
Water-dilutable concentrates for the coating of various substrates
The present invention relates to concentrated inorganic/organic sols that are readily diluted with water to form coating agents for textile materials. Further, the use of the aqueous formulations, especially for the washproof coating of a textile material. |
| US08309469B2 |
Method of fabricating semiconductor device
A method of fabricating a semiconductor device includes forming core material patterns comprising first films separated from another above a substrate; modifying surfaces of core material patterns so a second film is formed, selectively etchable, with first films internally remaining, the second film not covering a base layer of core material patterns between core material patterns; covering an upper surface and sides of the second film and forming a third film on the substrate; etching back the third film to expose an upper surface of the second film and the base layer of core material patterns between the patterns, causing the third film to selectively remain; removing the second film more rapidly than the first and third films; and patterning the base layer with the first and third films remaining on the base layer serving as a mask after the second film has been removed, forming a base layer pattern. |
| US08309468B1 |
Chemical mechanical polishing composition and method for polishing germanium-antimony-tellurium alloys
A method for chemical mechanical polishing of a substrate comprising a germanium-antimony-tellurium chalcogenide phase change alloy (GST) using a chemical mechanical polishing composition consisting essentially of, as initial components: water; an abrasive; a material selected from ethylene diamine tetra acetic acid and salts thereof; and an oxidizing agent; wherein the chemical mechanical polishing composition facilitates a high GST removal rate with low defectivity. |
| US08309466B2 |
Polishing pad
A polishing pad has an excellent polishing rate and is superior in longevity without generating center slow. A method of manufacturing a semiconductor device with the polishing pad is also provided. The polishing pad has a polishing layer consisting of a polyurethane foam having fine cells, wherein a high-molecular-weight polyol component that is a starting component of the polyurethane foam contains a hydrophobic high-molecular-weight polyol A having a number-average molecular weight of 550 to 800 and a hydrophobic high-molecular-weight polyol B having a number-average molecular weight of 950 to 1300 in an A/B ratio of from 10/90 to 50/50 by weight. |
| US08309463B2 |
Method for forming fine pattern in semiconductor device
A method for forming a contact hole of a semiconductor device according to the present invention forms a contact hole which is defined as a new contact hole region (a second contact hole region), between spacers as well as a contact hole defined within the spacer (a first contact hole region) by a spacer patterning technology (SPT). The present invention with this method can help to form a fine contact hole as a double patterning is used, even with one mask. |
| US08309456B2 |
Method and system for metal barrier and seed integration
A method for making an electrode in a semiconductor device. The method includes forming a trench in a first layer. The first layer is associated with a top surface, and the trench is associated with a bottom surface and a side surface. Additionally, the method includes depositing a diffusion barrier layer on at least the bottom surface, the side surface, and a part of the top surface, removing the diffusion barrier layer from at least a part of the bottom surface, depositing a seed layer on at least the part of the bottom surface and the diffusion barrier layer, and depositing an electrode layer on the seed layer. |
| US08309453B2 |
Multilevel interconnects structure with shielding function and fabricating method thereof
A method of fabricating multilevel interconnects includes providing a substrate having a pixel array area and a logical circuit area, forming a first dielectric layer on the substrate, performing a first metallizing process on the first dielectric layer to form a first patterned metal layer and a second patterned metal layer above the pixel array area and the logical circuit area respectively, forming a second dielectric layer on the first patterned metal layer, the second patterned metal layer, and the first dielectric layer, performing a second metallizing process on the second dielectric layer to form a third patterned metal layer and a fourth patterned metal layer above the pixel array area and the logical circuit area respectively, wherein patterns of the fourth and the second patterned metal layer interlace to completely cover the logical circuit area, and depositing a dielectric layer on the third and the fourth patterned metal layer. |
| US08309452B2 |
Method of forming an inductor on a semiconductor wafer
A semiconductor device has a substrate with an inductor formed on its surface. First and second contact pads are formed on the substrate. A passivation layer is formed over the substrate and first and second contact pads. A protective layer is formed over the passivation layer. The protective layer is removed over the first contact pad, but not from the second contact pad. A conductive layer is formed over the first contact pad. The conductive layer is coiled on the surface of the substrate to produce inductive properties. The formation of the conductive layer involves use of a wet etchant. The second contact pad is protected from the wet etchant by the protective layer. The protective layer is removed from the second contact pad after forming the conductive layer over the first contact pad. An external connection is formed on the second contact pad. |
| US08309451B2 |
Semiconductor device and method of providing common voltage bus and wire bondable redistribution
A semiconductor wafer contains a plurality of semiconductor die. The wafer has contact pads formed over its surface. A passivation layer is formed over the wafer. A stress buffer layer is formed over the passivation layer. The stress buffer layer is patterned to expose the contact pads. A metal layer is deposited over the stress buffer layer. The metal layer is a common voltage bus for the semiconductor device in electrical contact with the contact pads. An adhesion layer, barrier layer, and seed layer is formed over the wafer in electrical contact with the contact pads. The metal layer is mounted to the seed layer. Solder bumps or other interconnect structures are formed over the metal layer. A second passivation layer is formed over the metal layer. In an alternate embodiment, a wirebondable layer can be deposited over the metal layer and wirebonds connected to the metal layer. |
| US08309442B2 |
Semiconductor stacking layer and fabricating method thereof
A fabricating method of a semiconductor stacking layer includes following steps. First, an amorphous silicon (α-Si) layer is formed on a substrate. Surface treatment is then performed on a surface of the α-Si layer. After that, a doped microcrystalline silicon (μc-Si) layer is formed on the treated surface of the α-Si layer, wherein interface defects existing between the α-Si layer and the doped μc-Si layer occupy an area in a cross-sectional region having a width of 1.5 micrometers and a thickness of 40 nanometers, and a ratio of the occupied area in the cross-sectional region is equal to or less than 10%. The method of fabricating the semiconductor stacking layer can be applied to a fabrication process of a semiconductor device to effectively reduce the interface defects of the semiconductor stacking layer. |
| US08309441B2 |
Process for eliminating delamination between amorphous silicon layers
One embodiment is a method of forming a circuit structure. The method comprises forming a first amorphous layer over a substrate; forming a first glue layer over and adjoining the first amorphous layer; forming a second amorphous layer over and adjoining the first glue layer; and forming a plurality of posts separated from each other by removing a first portion of the first amorphous layer and a first portion of the second amorphous layer. At least some of the plurality of posts each comprises a second portion of the first amorphous layer, a first portion of the first glue layer, and a second portion of the second amorphous layer. |
| US08309440B2 |
Method and apparatus for cleaning a substrate surface
Embodiments described herein provide methods for processing a substrate. One embodiment comprises positioning a substrate in a processing region of a processing chamber, exposing a surface of the substrate disposed in the processing chamber to an oxygen containing gas to form a first oxygen containing layer on the surface, removing at least a portion of the first oxygen containing layer to expose at least a portion of the surface of the substrate, and exposing the surface of the substrate to an oxygen containing gas to form a second oxygen containing layer on the surface. |
| US08309434B2 |
Method for manufacturing semiconductor device including semiconductor elements with electrode formed thereon
A semiconductor device includes: a semiconductor element having first and second surfaces, wherein the semiconductor element includes at least one electrode, which is disposed on one of the first and second surfaces; and first and second metallic layers, wherein the first metallic layer is disposed on the first surface of the semiconductor element, and wherein the second metallic layer is disposed on the second surface of the semiconductor element. The one electrode is electrically coupled with one of the first and second metallic layers, which is disposed on the one of the first and second surfaces. The one electrode is coupled with an external circuit through the one of the first and second metallic layers. |
| US08309431B2 |
Method for self-supported transfer of a fine layer by pulsation after implantation or co-implantation
A method for self-supported transfer of a fine layer, in which at least one species of ions is implanted in a source-substrate at a specified depth in relation to the surface of the source-substrate. A stiffener is applied in intimate contact with the source-substrate and the source-substrate undergoes a heat treatment at a specified temperature during a specified period of time in order to create an embrittled buried area substantially at the specified depth without causing a thin layer, defined between the surface and the embrittled buried layer in relation to the remainder of the source-substrate, to become thermally detached. A controlled localized energy pulse is applied to the source-substrate in order to cause the self-supported detachment of the thin layer. |
| US08309429B2 |
Method for manufacturing semiconductor substrate and semiconductor device
A plurality of single crystal semiconductor substrates are arranged and then the plurality of single crystal semiconductor substrates which have been arranged are overlapped with a base substrate, so that the base substrate and the plurality of single crystal semiconductor substrates are bonded to each other. Then, each of the plurality of single crystal semiconductor substrates is separated to form a plurality of single crystal semiconductor layers over the base substrate. Next, in order to reduce crystal defects in the plurality of single crystal semiconductor layers, the plurality of single crystal semiconductor layers are irradiated with a laser beam. The plurality of single crystal semiconductor layers are thinned by being etched before or after irradiation with a laser beam. |
| US08309426B2 |
Methods for manufacturing multilayer wafers with trench structures
The present invention provides methods for the manufacture of a trench structure in a multilayer wafer that comprises a substrate, an oxide layer on the substrate and a semiconductor layer on the oxide layer. These methods include the steps of forming a trench through the semiconductor layer and the oxide layer and extending into the substrate, and of performing an anneal treatment of the formed trench such that at the inner surface of the trench some material of the semiconductor layer flows at least over a portion of the part of the oxide layer exposed at the inner surface of the trench. Substrates manufactured according to this invention are advantageous for fabricating various semiconductor devices, e.g., MOSFETs, trench capacitors, and the like. |
| US08309424B2 |
Methods of forming electrically insulative materials, methods of forming low k dielectric regions, and methods of forming semiconductor constructions
Some embodiments include methods of forming low k dielectric regions between electrically conductive lines. A construction may be formed to have a plurality of spaced apart electrically conductive lines, and to have sacrificial material between the electrically conductive lines. The sacrificial material may be removed. Subsequently, electrically insulative material may be deposited over and between the lines. The deposition of the insulative material may occur under conditions in which bread-loafing of the insulative material creates bridges of the insulative material across gas-filled gaps between the lines. The gas-filled gaps may be considered to correspond to low k dielectric regions between the electrically conductive lines. In some embodiments the sacrificial material may be carbon. In some embodiments, the deposited insulative material may be a low k dielectric material, and in other embodiments the deposited insulative material may not be a low k dielectric material. |
| US08309422B2 |
Low clamp voltage ESD method
In one embodiment, an ESD device is configured to include a zener diode and a P-N diode and to have a conductor that provides a current path between the zener diode and the P-N diode. |
| US08309421B2 |
Dual-bulb lamphead control methodology
The present invention generally relates to methods of controlling UV lamp output to increase irradiance uniformity. The methods generally include determining a baseline irradiance within a chamber, determining the relative irradiance on a substrate corresponding to a first lamp and a second lamp, and determining correction or compensation factors based on the relative irradiances and the baseline irradiance. The lamps are then adjusted via closed loop control using the correction or compensation factors to individually adjust the lamps to the desired output. The lamps may optionally be adjusted to equal irradiances prior to adjusting the lamps to the desired output. The closed loop control ensures process uniformity from substrate to substrate. The irradiance measurement and the correction or compensation factors allow for adjustment of lamp set points due to chamber component degradation, chamber component replacement, or chamber cleaning. |
| US08309420B1 |
Fabrication of semiconductor architecture having field-effect transistors especially suitable for analog applications
A semiconductor structure is provided with (i) an empty well having relatively little well dopant near the top of the well and (ii) a filled well having considerably more well dopant near the top of the well. Each well is defined by a corresponding body-material region (108 or 308) of a selected conductivity type. The regions respectively meet overlying zones (104 and 304) of the opposite conductivity type. The concentration of the well dopant reaches a maximum in each body-material region no more than 10 times deeper below the upper semiconductor surface than the overlying zone's depth, decreases by at least a factor of 10 in moving from the empty-well maximum-concentration location through the overlying zone to the upper semiconductor surface, and increases, or decreases by less than a factor of 10, in moving from the filled-well maximum-concentration location through the other zone to the upper semiconductor surface. |
| US08309419B2 |
CMOS integration with metal gate and doped high-K oxides
A method and apparatus are described for fabricating single metal gate electrodes (35, 36) over a high-k gate dielectric layer (31, 32) that is separately doped in the PMOS and NMOS device areas (96, 97) by forming first capping oxide layer (23) with a first dopant species on a high-k gate dielectric layer (22) in at least the NMOS device area and also forming second capping oxide layer (27) with a second dopant species on a high-k gate dielectric layer (22) in at least the PMOS device area, where the first and second dopant species are diffused into the gate dielectric layer (22) to form a first fixed charge layer (31) in the PMOS device area of the high-k gate dielectric area and a second fixed charge layer (32) in the NMOS device area of the high-k gate dielectric area. |
| US08309418B2 |
Field effect transistor device with shaped conduction channel
A field effect transistor device includes a substrate, a silicon germanium (SiGe) layer disposed on the substrate, gate dielectric layer lining a surface of a cavity defined by the substrate and the silicon germanium layer, a metallic gate material on the gate dielectric layer, the metallic gate material filling the cavity, a source region, and a drain region. |
| US08309417B2 |
Vertical-type semiconductor devices and methods of manufacturing the same
In a vertical-type memory device and a method of manufacturing the vertical-type memory device, the vertical memory device includes an insulation layer pattern of a linear shape provided on a substrate, pillar-shaped single-crystalline semiconductor patterns provided on both sidewalls of the insulation layer pattern and transistors provided on a sidewall of each of the single-crystalline semiconductor patterns. The transistors are arranged in a vertical direction of the single-crystalline semiconductor pattern, and thus the memory device may be highly integrated. |
| US08309412B2 |
Method for forming semiconductor device with buried gate structure
A method for forming a semiconductor device includes: etching a hard mask layer and a conductive layer formed on a semiconductor substrate, a lower structure being formed on the semiconductor substrate; forming a sacrificial insulating layer at upper parts of the etched hard mask layer and the etched conductive layer of a peripheral circuit region; forming an isolation insulating layer at an upper part of an isolation insulating layer of a cell region; forming spacers at sidewalls of the etched hard mask layer, the etched conductive layer, and the isolation insulating layer of the cell region, respectively; forming storage electrode contact plugs at both sides of each of the spacers, respectively; and removing the sacrificial insulating layer to expose the semiconductor substrate of the peripheral circuit region, and etching the lower structure to expose the semiconductor substrate of the peripheral circuit region. |
| US08309411B2 |
Semiconductor device and method of fabricating the same
A method of fabricating a semiconductor device includes forming an interlayer dielectric on a substrate, the interlayer dielectric including first and second openings respectively disposed in first and second regions formed separately in the substrate; forming a first conductive layer filling the first and second openings; etching the first conductive layer such that a bottom surface of the first opening is exposed and a portion of the first conductive layer in the second opening remains; and forming a second conductive layer filling the first opening and a portion of the second opening. |
| US08309409B2 |
Method for fabricating trench gate to prevent on voltage parasetic influences
A semiconductor-device fabrication method includes forming a second semiconductor region of a second conductivity on a surface layer of a first semiconductor region of a first conductivity, the second semiconductor region having an impurity concentration higher than the first semiconductor region; forming a trench penetrating the second semiconductor region, to the first semiconductor region; embedding a first electrode inside the trench via an insulating film, at a height lower than a surface of the second semiconductor region; forming an interlayer insulating film inside the trench, covering the first electrode; leaving the interlayer insulating film on only a surface of the first electrode; removing the second semiconductor region such that the surface thereof is positioned lower than an interface between the first electrode and the interlayer insulating film; and forming a second electrode contacting the second semiconductor region and adjacent to the first electrode via the insulating film in the trench. |
| US08309408B2 |
Particle quantifying systems and methods using acoustic radiation pressure
A method for fractionating particles includes flowing a fluid having particles therein along a first channel, applying acoustic radiation pressure to the fluid, focusing the particles within the fluid into a single file line, moving the particles in a flow rate, applying acoustic radiation pressure to the fluid for a second time, focusing the particles based on size and acoustic contrast, producing at least two fluid fractions of the particles, and collecting at least one of the fractions. |
| US08309407B2 |
Electronic devices including carbon-based films having sidewall liners, and methods of forming such devices
Methods in accordance with aspects of this invention form microelectronic structures in accordance with other aspects of this invention, such as non-volatile memories, that include (1) a layerstack having a pattern including sidewalls, the layerstack comprising a resistivity-switchable layer disposed above and in contact with a bottom electrode, and a top electrode disposed above and in contact with the resistivity-switchable layer; and (2) a dielectric sidewall liner in contact with the sidewalls of the layerstack; wherein the resistivity-switchable layer includes a carbon-based material, and the dielectric sidewall liner includes an oxygen-poor dielectric material. Numerous additional aspects are provided. |
| US08309403B2 |
Method for encapsulating electronic components on a wafer
A method for encapsulating electronic components, including the steps of: forming, in a first surface of a semiconductor wafer, electronic components; forming, on the first surface, an interconnection stack including conductive tracks and vias separated by an insulating material; forming first and second bonding pads on the interconnection stack; thinning down the wafer, except at least on its contour; filling the thinned-down region with a first resin layer; arranging at least one first chip on the first bonding pads and forming solder bumps on the second bonding pads; depositing a second resin layer covering the first chips and partially covering the solder bumps; bonding an adhesive strip on the first resin layer; and scribing the structure into individual chips. |
| US08309402B2 |
Method of fabricating oxide material layer with openings attached to device layers
A manufacturing method of a semiconductor structure includes providing a substrate having an upper surface and a bottom surface. First openings are formed in the substrate. An oxidization process is performed to oxidize the substrate having the first openings therein to form an oxide-containing material layer, and the oxide-containing material layer has second openings therein. A conductive material is filled into the second openings to form conductive plugs. A first device layer is formed a first surface of the oxide-containing material layer, and is partially or fully electrically connected to the conductive plugs. A second device layer is formed on a second surface of the oxide-containing material layer, and is partially or fully electrically connected to the conductive plugs. |
| US08309398B2 |
Electronic device wafer level scale packages and fabrication methods thereof
Electronic device wafer level scale packages and fabrication methods thereof. A semiconductor wafer with a plurality of electronic devices formed thereon is provided. The semiconductor wafer is bonded with a supporting substrate. The back of the semiconductor substrate is thinned. A first trench is formed by etching the semiconductor exposing an inter-layered dielectric layer. An insulating layer is conformably deposited on the back of the semiconductor substrate. The insulating layer on the bottom of the first trench is removed to create a second trench. The insulating layer and the ILD layer are sequentially removed exposing part of a pair of contact pads. A conductive layer is conformably formed on the back of the semiconductor. After the conductive layer is patterned, the conductive layer and the contact pads construct an S-shaped connection. Next, an exterior connection and terminal contact pads are subsequently formed. |
| US08309395B2 |
Method of fabricating a high-temperature compatible power semiconductor module
The invention relates to a method for fabricating a high-temperature compatible power semiconductor module in which a power semiconductor chip is bonded by means of a diffusion solder layer to a substrate and said substrate is bonded by means of silver sintered layer to a base plate, after which a bonding element is bonded to the top chip metallization. To prevent oxidation of the predefined bond area when producing the diffusion solder layer and the sintered silver layer 4′ an anti-oxidation layer is applied to the top chip metallization at least in the region of the predefined bond area. |
| US08309393B2 |
Method of producing a single-crystal thin film of an organic semiconductor compound
A method of producing a single-crystal thin film of an organic semiconductor compound, which contains the steps of: applying an organic solvent which has a dielectric constant of 4.5 or greater and in which an organic semiconductor compound is soluble, on a substrate, to form a liquid film of the organic solvent on the substrate; supplying the organic semiconductor compound into the liquid film of the organic solvent, to dissolve therein; and crystallizing the organic semiconductor compound in the organic solvent. |
| US08309391B2 |
Method for manufacturing an array-type nanotube layer of a thin-film solar cell
A method for manufacturing an array-type nanotube layer for a thin-film solar cell comprises the steps of: preparing an isotropic Si-substrate; sputtering a metal Ti layer onto the isotropic Si-substrate; heat-treating the Ti-coated Si-substrate in a vacuum heat-treatment environment; annealing the Ti-coated Si-substrate in an annealing heat-treatment environment to produce an intermediate-phase metal Ti layer; anodizing the intermediate-phase metal Ti layer so as to transform the intermediate-phase metal Ti layer into an array-type nanotube layer for the solar cell; and finally applying a reverse voltage to separate the array-type nanotube layer from the isotropic Si-substrate. |
| US08309388B2 |
MEMS package having formed metal lid
A hermetic MEMS device (100) comprising a carrier (110) having a surface (111) including a device (101) and an attachment stripe (122), the stripe spaced from the device and surrounding the device; a metallic foil (102) having a central bulge portion (103) and a peripheral rim portion (104) meeting the stripe, the bulge cross section parallel to the carrier monotonically decreasing from the rim (104) towards the bulge apex (105); and the foil positioned over the carrier surface so that the bulge arches over the device and the rim forms a seal with the stripe. |
| US08309380B2 |
Photodiode array, method for manufacturing photodiode array, epitaxial wafer, and method for manufacturing epitaxial wafer
Provided are a photodiode array and its manufacturing method, which maintain the crystalline quality of an absorption layer formed on a group III-V semiconductor substrate to obtain excellent characteristics, and which improve the crystallinity at the surface of a window layer; an epitaxial wafer used for manufacturing the photodiode array; and a method for manufacturing the epitaxial wafer. A method for manufacturing a photodiode array 1 having a plurality of absorption regions 21, includes the steps of: growing an absorption layer 7 on an n-type InP substrate 3; growing an InP window layer on the absorption layer 7; and diffusing a p-type impurity in regions, in the window layer 11, corresponding to the plurality of absorption regions 21. The window layer 11 is grown by MOVPE using only metal-organic sources, at a growth temperature equal to or lower than that of the absorption layer 7. |
| US08309379B2 |
Flexible substrate and method for fabricating flexible display device having the same
A method for fabricating a flexible display device including the steps of preparing a glass substrate, forming a flexible substrate on the glass substrate, the flexible substrate being formed by forming a semiconductor layer on the glass substrate, forming a first flexible layer on the semiconductor layer, forming an adhesive layer on the first flexible layer, and forming a second flexible layer on the adhesive layer, forming a thin film array on the flexible substrate, forming a display device on the thin film array, and separating the glass substrate from the semiconductor layer of the flexible substrate. |
| US08309378B2 |
Method of fabricating a light emitting diode chip having phosphor coating layer
A method of fabricating light emitting diode chips having a phosphor coating layer comprises providing a substrate having a plurality of light emitting diodes formed thereon; forming a conductive bump on at least one of the plurality of light emitting diodes; forming a phosphor coating layer over the substrate and the light emitting diodes; cutting the phosphor coating layer by a point cutter to remove an upper portion of the phosphor coating layer, so as to reduce a thickness of the phosphor coating layer and expose the conductive bump; and forming a plurality of individual light emitting diode chips having the phosphor coating layer by separating the plurality of light emitting diodes. |
| US08309377B2 |
Fabrication of reflective layer on semiconductor light emitting devices
Fabrication of Reflective Layer on Semiconductor Light emitting diodes A method for fabrication of a reflective layer on a semiconductor light emitting diode, the semiconductor light emitting diode having a wafer with multiple epitaxial layers on a substrate; the method comprising applying a first ohmic contact layer on a front surface of the multiple epitaxial layers, the first ohmic contact layer being of a reflective material to also act as a reflective layer. |
| US08309376B2 |
Process and materials for making contained layers and devices made with same
There is provided a process for forming a contained second layer over a first layer. The process comprises forming the first layer having a first surface energy and then treating the first layer with a photocurable surface-active composition which is a fluorinated ester or fluorinated imide of an α,β-unsaturated polyacid; exposing the photocurable surface-active composition patternwise with radiation resulting in exposed areas and unexposed areas; developing the photocurable surface-active composition to remove the unexposed areas resulting in a first layer having untreated portions in the unexposed areas and treated portions in the exposed areas, where the treated portions have a second surface energy that is lower than the first surface energy; and forming the second layer on the untreated portions of the first layer. There is also provided an organic electronic device made by the process. |
| US08309375B2 |
Light emitting device and display
A method for manufacturing a light emitting device comprises: preparing a light emitting component having an active layer of a semiconductor, the active layer comprising a gallium nitride based semiconductor containing indium and being capable of emitting a blue color light; preparing a phosphor capable of absorbing a part of the blue color light emitted from the light emitting component and emitting a yellow color light, wherein selection of the phosphor is controlled based on an emission wavelength of the light emitting component; and combining the light emitting component and the phosphor so that the blue color light from the light emitting component and the yellow color light from the phosphor are mixed to make a white color light. |
| US08309373B2 |
Method of manufacturing semiconductor device
A method of manufacturing a semiconductor device includes: forming a first pad and a second pad over a substrate; forming a first insulating film over the second pad without forming the first insulating film over the first pad; forming a metal film over the first pad and the second pad; forming an electrode over the first pad with the metal film interposed therebetween; selectively removing the metal film over the second pad; and removing the first insulating film over the second pad. |
| US08309371B1 |
System and method for creating a flat wavefront using a photonic crystal
A system and method include forming an optical cavity by positioning a photonic crystal a predetermined distance from a substrate, and creating, within the cavity, a standing wave having a substantially flat wavefront. The standing wave may be created by applying an input wave to a first surface of the photonic crystal. The predetermined distance may be such that a peak intensity of the standing wave is proximate to or a calculated distance from the substrate surface. The peak intensity may vary in relation to the substrate surface. The method may include tuning the peak intensity location within the cavity by shifting the wavelength of the input wave or altering the characteristics of the photonic crystal by an external field. A second photonic crystal may be used on the other side of the substrate to replace the reflecting properties of the substrate, allowing for further smoothing of the wavefront. |
| US08309367B2 |
Microwave microfluidics
The present invention concerns a novel means by which liquids can be moved or mixed. Microwaves strike and heat materials that are highly susceptible to microwave heating. The susceptible materials are on, within, or near materials that melt or change shape in response to temperature increases. Upon microwave irradiation, these materials change shape (e.g., shrink or melt), causing the movement of liquids. The invention is important in many microfluidics applications, especially in biomedical analysis, where it is valuable to be able to move small volumes of liquids (e.g., on a microarray chip). |
| US08309366B2 |
Methods and devices to enhance sensitivity and evaluate sample adequacy and reagent reactivity in rapid lateral flow immunoassays
Methods and devices for rapid lateral flow immunoassays to detect specific antibodies within a liquid sample while also validating the adequacy of the liquid sample for the presence of immunoglobulin and the integrity and immunoreactivity of the test reagents that detect the antibodies of interest, without requiring instrumentation. The methods and devices provide for delivery of a diluted liquid sample to a single location that simultaneously directs the liquid flow along two or more separate flow paths, one that serves as a positive control to confirm that all critical reagents of the test are immunoreactive, and that the sample being tested is adequate, and the other to detect specific antibodies if present. |
| US08309363B2 |
Apparatus and method for evaluating a hydrocarbon to determine the propensity for coke formation
An apparatus (10) for evaluating a liquid hydrocarbon to determine the propensity for coke formation comprising an injector (12), a supply of air (14) arranged to supply air to the injector (12) and a supply of liquid hydrocarbon (16) arranged to supply liquid hydrocarbon to the injector (12). The injector (12) is arranged to atomise the liquid hydrocarbon and to supply the air and atomised liquid hydrocarbon into a chamber (18) and the chamber (18) is arranged to supply atomised liquid hydrocarbon and air to a test pipe (20) and a heater (22) is arranged to heat the test pipe (20). The test pipe (20) is pivotably mounted on a frame (28) such that the orientation of the test pipe (20) relative to the frame (28) is variable. The apparatus (10) is able to simulate conditions within a vent pipe of a lubricant system of an aero gas turbine engine. |
| US08309359B2 |
Isobaric tags for analyte detection and quantification
Isobaric reagents for labeling analytes are provided. The isobaric reagents have facile design and synthesis that allows for differential labeling of an unlimited number of analyte samples. |
| US08309357B2 |
Analyte-testing device
A device adapted to determine an analyte concentration of a fluid sample using a test sensor. The device comprises a display adapted to display information to a user. The device further comprises at least one user-interface mechanism adapted to allow the user to interact with the device. The device further comprises a body portion including at least one opening formed therein, the at least one opening being of sufficient size to receive the test sensor. The device further comprises a memory adapted to store a plurality of stored analyte concentrations. The device further comprises a processing feature adapted to inhibit the stored analyte concentrations from being displayed on the display. |
| US08309347B2 |
Cell expansion system and methods of use
Cell expansion systems and methods of use are provided. The cell expansion systems generally include a hollow fiber cell growth chamber, and first and second circulation loops (intracapillary loops and extracapillary loops) associated with the interior of the hollow fibers and exterior of the hollow fibers, respectively. Detachable flow circuits and methods of expanding cells are also provided. |
| US08309346B2 |
Apparatus for the non-invasive measurement of tissue function and metabolism by determination of steady-state fluorescence anisotropy
A non-invasive measurement of biological tissue reveals information about the function of that tissue. Polarized light is directed onto the tissue, stimulating the emission of fluorescence, due to one or more endogenous fluorophors in the tissue. Fluorescence anisotropy is then calculated. Such measurements of fluorescence anisotropy are then used to assess the functional status of the tissue, and to identify the existence and severity of disease states. Such assessment can be made by comparing a fluorescence anisotropy profile with a known profile of a control. |
| US08309344B2 |
Automatic system of isolating and incubating circulating tumor cells
The present invention is applied in fields like biological medicine and tissue engineering. A fluid control system in a cell isolation and culture system is used to automatically process sample preparation, circulating tumor cell (CTC) isolation, plate changing and cell culturing. By using the present invention, time and labor are saved; moreover, the present invention has a small size and is easily carried. |
| US08309341B2 |
2-mercaptocyclopentanecarboxylic acid compounds, a process for their preparation and pharmaceutical compositions containing them
Compounds of formula (I): wherein: R1 represents a hydrogen atom or a group of formula COR4, or R1 represents a group of formula (A): R2 represents a group of formula NR5R6, or R2 represents a nitrogen-containing heterocyclic group, an aryl group or a heteroaryl group, R3 represents a hydrogen atom or an alkyl group, m represents an integer between 1 and 6 inclusive, n represents 0, 1 or 2, their optical isomers, and also addition salts thereof with a pharmaceutically acceptable acid. Medicinal products containing the same which are useful in treating and/or preventing thrombotic events. |
| US08309336B2 |
Family 8 enzymes with xylanolytic activity
The present invention describes a method to improve the properties of a dough and/or a baked product by adding a bread or dough-improving agent containing a enzyme with xylanolytic activity belonging to glycoside hydrolases family 8. Preferred enzymes are the psychrophilic xylanase from Pseudoalteromonas haloplanktis and the mesophilic xylanase Y from Bacillus halodurans C-125. |
| US08309335B2 |
Selective 5′ ligation tagging of RNA
The present invention provides novel compositions, kits and methods employing RNA 5′ polyphosphatases, RNA 5′ monophosphatases, capping enzymes, decapping enzymes, nucleic acid pyrophosphatases and RNA ligases, as well as other enzymes, for selective 5′ ligation tagging of desired classes of RNA molecules that differ with respect to particular chemical moieties on their 5′ ends. The 5′ tagged RNA molecules can be used for synthesis of tagged first-stand cDNA, double-stranded cDNA, and sense or antisense RNA for a variety of uses. |
| US08309334B2 |
Method for producing highly impact-resistant granules
The present invention provides highly impact-resistant, water-soluble or water dispersible, low-dust granules comprising an active ingredient and methods for obtaining the same. |
| US08309332B2 |
GRG23 and GRG51 polypeptides having herbicide resistance activity
Compositions and methods for conferring herbicide resistance or tolerance to bacteria, plants, plant cells, tissues and seeds are provided. Compositions include polynucleotides encoding herbicide resistance or tolerance polypeptides, vectors comprising those polynucleotides, and host cells comprising the vectors. The nucleotide sequences of the invention can be used in DNA constructs or expression cassettes for transformation and expression in organisms, including microorganisms and plants. Compositions also comprise transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated polynucleotides encoding glyphosate resistance or tolerance polypeptides are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated polynucleotides comprising nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO:2, 4, or 6, or the nucleotide sequence set forth in SEQ ID NO:1, 3, or 5. The present invention additionally provides a method to measure enzyme kinetic activity using fluorogenic substrates. |
| US08309331B2 |
Systems and methods for altering rates of enzymatic processes
The various embodiments of the present invention relate generally to compositions, systems, and methods for altering rates of catalysis. More particularly, the various embodiments of the present invention are directed toward compositions, systems, and methods for enzymatic hydrolysis of polysaccharides, such as cellulose and starch. An aspect of the present invention comprises a method for altering the rate of conversion of a substrate into a product comprising: providing a substrate in a carrier; mixing a reactant and a co-factor with the carrier to form a substantially homogeneous mixture of the reactant, the co-factor, and the substrate in the carrier; and reacting the reactant with the substrate in the presence of the co- factor to convert at least a portion of the substrate into the product, wherein the reaction rate of the reactant with the substrate in the presence of the co-factor is different than the reaction rate of the reactant with the substrate in the absence of the co-factor. |
| US08309322B2 |
Diterpene modulator of macrophage phagosomal maturation
Novel uses for diterpene modulators of macrophage phagosomal maturation are provided. The diterpene isotuberculosinol is used as an immune modulator, assay for pharmaceutical compositions and an isolated Mycobacterium tuberculosis labdane-related diterpenoid virulence factor. A method of treating Mycobacterium tuberculosis infectivity is further provided. |
| US08309321B2 |
Screening method for identifying protease secretion-deficient mutants of microorganisms
A method for identifying a protease secretion deficient strain of a microorganism involves producing a mutant of the microorganism, followed by adding the mutant to gel-filled wells of a microtitration plate, incubating the mutant in the gel-filled wells under conditions call sing the mutant to secrete proteins, separating the mutant from the gel, and measuring activity of a secretion protease of the microorganism in the gel, wherein either (i) the gel is a substrate for the secretion protease or (ii) the gel contains a substrate for the secretion protease. |
| US08309318B2 |
Detection of antigen specific immunocomplexes
The present invention relates to methods and devices for detecting biological entities and components associated with hypersensitivity reactions in patients with allergies, cancer or autoimmune disease. Specifically, the assays of the invention are capable of qualitatively and/or quantitatively detecting allergen specific immunocomplexes by assaying for immobilized C3b in a biological sample produced as a result of exposure to food. |
| US08309310B2 |
Generic kinase/phosphatase assay with single readout
The present invention relates to a generic method for detecting a kinase or phosphatase activity. The method comprises the following steps: incubating a kinase or phosphatase activity sample with a kinase or phosphatase substrate molecule comprising either a fluorophore having a detectable readout or molecule with an aromatic group which serves as a quencher of the fluorophore, incubating the mixture of step a) with a detection entity comprising either a fluorophore or a molecule with an aromatic group and a binding partner, wherein the substrate molecule and the detection entity are capable of binding to the binding partner and the binding of the substrate molecule and the detection entity to the binding partner lead to an altered readout of the fluorophore, and measuring the readout of the fluorophore in the mixture of step b), wherein an altered readout of the fluorophore compared to a blank is indicative for the presence of a kinase or phosphatase activity in the sample. |
| US08309305B2 |
Method for discriminating between nucleotide sequences of nucleic acids
The present invention describes methods for discriminating between nucleotide sequences of first and second nucleic acids, including: providing a reaction solution, including a deoxynucleotide triphosphate, a DNA polymerase with strand displacement ability, a template nucleic acid fragment, a primer, and a mask oligo; incubating the reaction solution, obtaining a polymerase reaction, and producing an amplification product; detecting the amplification product to discriminate between the nucleotide sequences, wherein the primer is complementary to the first nucleic acid, the mask oligo hybridizes to the nucleotide sequence portion of the first and second nucleic acid, wherein the mask oligo is more complementary to the second nucleic acid than to the first nucleic acid, and wherein the mask oligo is not an origin of an elongation reaction with the polymerase, and a primer portion and a mask oligo portion hybridize to the same regions on the first and second nucleic acid. |
| US08309304B2 |
Label-free optical sensing and characterization of biomolecules by d8 or d10 metal complexes
The present invention provides a composition for detecting and/or characterizing a multiple-charged biomolecule comprising a charged d8 or d10 metal complex, wherein the metal complex electrostatically binds to the multiple-charged biomolecule to induce aggregation and self-assembly of the metal complex through metal-metal interactions, π . . . π interactions, or a combination of both interactions. The present invention further provides assay methods and kits for label-free optical detection and/or characterization of biomolecules carrying multiple charges, e.g., single-stranded nucleic acids, using a composition comprising a charged d8 or d10 metal complex. |
| US08309301B2 |
Sequences diagnostic for shrimp pathogens
Primers have been isolated that are diagnostic for the detection of the white spot syndrome virus (WSSV). The primers are based on a new portion of the WSSV genome and may be used in primer directed amplification or nucleic acid hybridization assay methods. |
| US08309300B2 |
Cysteine engineered antibodies and conjugates
Antibodies are engineered by replacing one or more amino acids of a parent antibody with non cross-linked, highly reactive cysteine amino acids. Antibody fragments may also be engineered with one or more cysteine amino acids to form cysteine engineered antibody fragments (ThioFab). Methods of design, preparation, screening, and selection of the cysteine engineered antibodies are provided. Cysteine engineered antibodies (Ab), optionally with an albumin-binding peptide (ABP) sequence, are conjugated with one or more drug moieties (D) through a linker (L) to form cysteine engineered antibody-drug conjugates having Formula I: Ab-(L-D)p I where p is 1 to 4. Diagnostic and therapeutic uses for cysteine engineered antibody drug compounds and compositions are disclosed. |
| US08309299B2 |
Combination therapy and method for assessing resistance to treatment
The present invention relates to a method for determining a subject's resistance to treatment with 2,2-dimethyl-N-((S)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-N′-(2,2,3,3,3-pentafluoro-propyl)-malonamide by measuring the levels a biomarker or biomarkers present in a biological sample obtained from the subject, the biomarker being IL6 and/or IL8. The present invention also relates to a combination therapy for a patient suffering from a proliferative disorder comprising administering to the patient 2,2-Dimethyl-N-((S)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-N′-(2,2,3,3,3-pentafluoro-propyl)-malonamide and an anti-IL6 and/or an anti-IL8 agent. |
| US08309298B2 |
Method for detecting protein
A method for detecting an analyte in a sample is described herein. The method comprises: preparing a complex immobilized solid phase comprising a solid phase and a complex on the solid phase; the complex comprising an analyte and a signal emitting substance; treating the complex immobilized solid phase with a blocking agent; and detecting the analyte based on a signal emitted from the signal emitting substance of the complex immobilized solid phase. |
| US08309294B2 |
Lithographic printing plate precursor and plate making method
A lithographic printing plate precursor includes: an aluminum support; an intermediate layer; and an image-recording layer, in this order, wherein at least one of the intermediate layer and the image-recording layer contains a compound having an amino group and a functional group capable of interacting with the aluminum support in a molecule. |
| US08309290B2 |
Toner and method of manufacturing the same
A toner including toner particles comprising a binder resin, a coloring agent and a wax. The toner particles are prepared by agglomerating and/or fusing at least two kinds of resin particulates and particles of the coloring agent dispersed in an aqueous medium. A first resin particulate among the at least two kinds of resin particulates contains a resin having a polyester skeleton and the wax. At least 50% by weight of the binder resin is polyester resins. |
| US08309286B2 |
Electrophotographic photoreceptor, process cartridge, and image forming apparatus
The invention provides an electrophotographic photoreceptor having at least a conductive substrate and a photosensitive layer formed on the conductive substrate wherein the outermost surface layer of the photoreceptor is composed of a cured material containing at least one compound represented by the formula (I) and a surfactant that contains, in the molecule thereof, at least one structure selected from (A) a structure that is obtained by polymerizing an acrylic monomer having a fluorine atom, (B) a structure having a carbon-carbon double bond and a fluorine atom, (C) an alkyleneoxide structure, and (D) a structure having a carbon-carbon triple bond and a hydroxy group. In formula (I), Q is an organic group having a valency of n and having hole transportability, R is a hydrogen atom or an alkyl group, L is a divalent organic group, n is 1 or more, and j is 0 or 1. |
| US08309285B2 |
Protective overcoat layer and photoreceptor including same
Disclosed is an electrophotographic imaging member that includes a substrate; a charge generating layer; a charge transport layer; and a protective overcoat layer having a polyol binder; a hole transport material; an acid catalyst; a leveling agent; and no melamine formaldehyde curing agent or cross-linking additive. Also disclosed is a process for forming a photoreceptor that includes providing a substrate; applying to it a charge generating layer, charge transport layer; and protective over coating layer having a polyol binder; a hole transport material; an acid catalyst; a leveling agent; and no melamine formaldehyde curing agent or cross-linking additive. Additionally provided is a method of forming an image with the disclosed electrophotographic imaging member. |
| US08309276B2 |
Process for preparing of a catalyst solution for fuel cell and a membrane electrode assembly using the same
The present invention discloses a process for preparing catalyst solution for a membrane-electrode assembly in a fuel cell, which comprises the steps of a) mixing a catalyst solution (Solution A) wherein catalyst particles are dispersed in water and an ion conductive resin solution (Solution B) wherein an ion conductive resin is dissolved in water, low boiling point organic solvent or a mixture thereof, to form a dispersion; b) mixing the dispersion obtained from step a) with functional additive dissolved in high boiling point solvent or a mixture of low boiling point solvent arid water (Solution C) to prepare catalyst ink dispersion; and c) aging the catalyst ink dispersion obtained from step b). |
| US08309273B2 |
Polymer electrolyte fuel cell and fuel cell stack including the same
A polymer electrolyte fuel cell includes: a membrane-electrode assembly (10) having a polymer electrolyte membrane (1) and a pair of electrodes (4, 8) sandwiching a portion of the polymer electrolyte membrane (1) which portion is located inwardly of a peripheral portion of the polymer electrolyte membrane (1); an electrically-conductive first separator (30) disposed to contact the membrane-electrode assembly (10) and formed such that a groove-like first reactant gas channel (37) is formed on one main surface thereof so as to bend; and an electrically-conductive second separator (20) disposed to contact the membrane-electrode assembly (10) and formed such that a groove-like second reactant gas channel (27) is formed on one main surface thereof so as to bend, wherein the first reactant gas channel (27) is formed such that a width of a portion of the first reactant gas channel (27) which portion is formed at least a portion (hereinafter referred to as an uppermost stream portion 8C of the first separator 30) located between a portion where the first reactant gas channel (27) extending from an upstream end thereof first contacts the electrode 8 and a portion where the second reactant gas channel (27) extending from an upstream end thereof first contacts the electrode 4 is smaller than a width of a portion of the first reactant gas channel (27) which portion is formed at a portion other than the uppermost stream portion 8C of the first separator 30. |
| US08309272B2 |
Solid oxide cell
A solid oxide cell is provided which, after short-time activation, can generate electricity at a high power density over a prolonged period. This cell can be constituted so as to eliminate the necessity of carrier gas introduction during power generation and, hence, can more easily realize a size reduction in power generation systems. The solid oxide cell at least has an anode having an anode material, a cathode having a cathode material, and an electrolyte disposed between the anode and the cathode and including an ionically conductive solid oxide, wherein the anode material includes a composite metal oxide or a cermet, solid carbon is deposited on the anode material during activation and at least the following reaction schemes (1) and (2) are utilized at the anode during power generation to generate electricity. CO2+C→2CO (1) CO+O2−→CO2+2e− (2) |
| US08309269B2 |
Fuel cell, membrane-electrode assembly, and membrane-catalyst layer assembly
A fuel cell of the present invention includes a membrane-electrode assembly (10), an anode separator (20), and a cathode separator (30). The membrane-electrode assembly (10) includes: a polymer electrolyte membrane (1); a first anode catalyst layer (2A) and an anode gas diffusion layer (4) sequentially stacked on one of main surfaces of the polymer electrolyte membrane (1); a second anode catalyst layer (2B) disposed between the polymer electrolyte membrane (1) and the first anode catalyst layer (2A); and a cathode catalyst layer (3) and a cathode gas diffusion layer (5) sequentially stacked on the other main surface of the polymer electrolyte membrane (1). The second anode catalyst layer (2B) contains a catalyst which adsorbs a sulfur compound. |
| US08309268B2 |
Sealing of a membrane electrode assembly
A sealed and/or reinforced membrane electrode assembly is disclosed. Encapsulation films, each comprising a backing layer and an adhesive layer, are positioned on the edges of at least one face of each gas diffusion substrate such that the adhesive layers impregnate into each gas diffusion substrate. Methods of forming sealed and/or reinforced membrane electrode assemblies are also disclosed. |
| US08309265B2 |
Electrolyte membrane for fuel cells, its production and fuel cell using the same
The present invention provides an electrolyte membrane for a fuel cell that has a minute projection cluster on one side or both sides of a polymer electrolyte membrane. Further, the present invention provides a production method of an electrolyte membrane for a fuel cell, wherein a mold comprising convex portions having a fixed planar pattern is pressed on one side or both sides of a polymer electrolyte membrane, then while concave portions of the polymer electrolyte membrane formed in the concave portions are being stretched, the mold is removed from the polymer electrolyte membrane for forming a minute projection cluster. |
| US08309258B2 |
Method for filling with electrode active material and method for producing all-solid-state cell
A solid electrolyte structure containing a porous solid electrolyte is prepared. At least the porous solid electrolyte of the solid electrolyte structure is immersed in a first sol solution containing at least a precursor of an electrode active material as a solute. Then, the first sol solution, in which the porous solid electrolyte is immersed, is heated. A solvent of the first sol solution is evaporated by the heating, whereby a pore of the porous solid electrolyte is filled with a high concentration (a large amount) of the electrode active material precursor. |
| US08309257B2 |
Method for producing solid electrolyte structure with porous portion and dense portion
A first fine particle-containing solution is deposited on an appropriate substrate, and dried to form a first fine particle aggregate layer. Polymer particles are deposited on the first fine particle aggregate layer, and are supplied with a second fine particle-containing solution such that the polymer particles are immersed in the second fine particle-containing solution. The second fine particle-containing solution is dried to form a second fine particle aggregate layer containing a large number of the polymer particles embedded. A first structure precursor is completed at this stage. Then, the first structure precursor is separated from the substrate, and thermally treated. Thus, the production of a first solid electrolyte structure, which has a porous solid electrolyte portion and a dense solid electrolyte portion integrated, is completed. |
| US08309256B2 |
Microporous film and method for producing the same
Provided is a microporous film formed of a thermoplastic resin composition comprising 100 parts by mass of (a) a polyolefin resin and from 5 to 90 parts by mass of (b) a polyphenylene ether resin; the microporous film having a sea-island structure with the polyolefin resin as a sea portion and with the polyphenylene ether resin as an island portion and having a air permeability of from 10 sec/100 cc to 5000 sec/100 cc. The microporous film does not break easily even at high temperatures and has good heat resistance. |
| US08309255B2 |
Electrochemical cell including electrolyte containing bis(oxalate)borate salt
An electrochemical cell includes a cathode with an aluminum current collector, a positive lead including aluminum, steel, or titanium coupled to the cathode current collector, an anode, and an electrolyte including up to 0.15M of a bis(oxalate) borate salt and an additional lithium salt. |
| US08309253B2 |
Titanium oxide, method for manufacturing the same, and lithium secondary battery using the same as active material
The present invention relates to a novel compound characterized by having a one-dimensional tunnel structure and being represented by the chemical formula H2Ti12O25, a method for manufacturing the same, and a lithium secondary battery containing, as a constituent thereof, an electrode produced by using the novel titanium oxide as an active material, and expected to demonstrate superior charge/discharge cycle characteristics over a long period of time as well as high capacity. |
| US08309251B2 |
Battery with electrode arrangement in relation to the holder
A battery includes a battery cell and a battery housing. The battery cell includes arcuate portions wherein an outer circumference of the battery cell is formed at least in part to be arcuate. The battery housing includes angular portions respectively opposing the arcuate portions and for storing the battery cell therein. Support walls having substantially the same curvatures as the arcuate portions and supporting the arcuate portions are formed along an insertion direction of the battery cell. |
| US08309248B2 |
Battery cell carrier assembly having a battery cell carrier for holding a battery cell therein
A battery cell carrier assembly having a battery cell carrier for holding a battery cell is provided. The battery cell carrier includes a trapping member for holding the battery cell. The battery cell carrier has at least one aperture extending therethrough for allowing air to flow therethrough to contact the first side of the battery cell for cooling the battery cell. The battery cell carrier further includes a panel member configured to be coupled to the trapping member for holding the battery cell therebetween. The panel member has at least one aperture extending therethrough for allowing air to flow therethrough to contact the battery cell for cooling the battery cell. |
| US08309247B2 |
Method for compressing individual cells in battery module
A battery module has a plurality of prismatic batteries (2) stacked in a thickness direction. Two plates (3, 4) are provided between each of the batteries (2), and each of the batteries (2) is compressed by shifting the two plates (3, 4) in directions away from each other. A pair of frame members (10, 20) having opposing surfaces (11, 21) extending along the stacking direction of the batteries (2) are disposed face to face so as to sandwich the batteries (2) in a direction perpendicular to the stacking direction of the batteries. Wedge-shaped spacers (12, 22) inserted between the two plates (3, 4) are provided respectively on the opposing surfaces. By narrowing the gap between the pair of frame members (10, 20), the spacers (12, 22) are allowed to advance inwardly between the two plates (3, 4) so that the two plates are shifted in directions away from each other, whereby the batteries are compressed. |
| US08309239B2 |
Perpendicular magnetic recording medium and method of manufacturing the same
A vertical magnetic recording disc (100) includes a base (10), a magnetic recording layer (22), and a medium protection layer (26). The magnetic recording layer (22) is a ferromagnetic layer having a granular structure where a granular portion is formed. The medium protection layer (26) contains nitrogen (N) atoms and carbon (C) atoms with a number ratio (N/C) in a range from 0.050 to 0.150. In a Raman spectrum obtained by exciting the medium protection layer (26) by argon ion laser light of wavelength 514.5 nm, from which a fluorescence is removed, the peak ratio Dh/Gh is in a range from 0.70 to 0.95, when a D peak Dh appearing in the vicinity of 1350 cm−1 is separated from G peak Gh appearing in the vicinity of 1520 cm−1 by the Gauss function. |
| US08309232B2 |
Running-in coating for gas turbines and method for production thereof
A running-in coating for gas turbines and a method for production of a running-in coating are provided. The running-in coating serves to seal a radial gap between a housing (11) of the gas turbine and the rotating blades (10) themselves, whereby the running-in coating (13) is applied to the housing. The running-in coating is made from a CoNiCrAIY-hBN material. The CoNiCrAIY-hBN material can be applied by thermal spraying, in particular plasma spraying. |
| US08309231B2 |
Acoustical tile
The present invention relates to an acoustical tile that includes a core and a surface treatment. The surface treatment comprises a formaldehyde-free latex binder, the binder including at least one formaldehyde-free biocide. The present invention also provides a process of manufacturing an acoustical tile. |
| US08309227B2 |
Carbon fibrous aggregator, method for manufacturing thereof, and composite material including thereof
Carbon fibrous aggregator obtained by a chemical vapor phase growing method, which comprises plural granular parts, and plural carbon fibers which are mutually independently extended outwardly from their respective granular parts so that each granular part is associated with two or more of carbon fibers, wherein the carbon fibers show a three dimensional expansion in all; and which show a three dimensional network structure of the carbon fibers at least in a part by a state that at least a part of the plural carbon fibers extended from one granular part is linked with another granular part; wherein mean length of carbon fibers which link two granular parts together is of 3.0-20.0 μm, and wherein a coefficient of variation, CV, ((standard deviation/mean value)×100) which is obtained on a determination of outer diameter distribution of the carbon fibers which constitute the aggregator of carbon fiber is not more than 30%. |
| US08309226B2 |
Electrically conductive transparent coatings comprising organized assemblies of carbon and non-carbon compounds
This invention is directed to an article comprising a transparent substrate and an electrically conductive transparent coating deposited on the transparent substrate. This invention is also directed to methods for preparing the electrically conductive transparent coating and depositing the coating on the transparent substrate. This invention is further directed to devices containing such articles. The electrically conductive transparent coating comprises carbon nanotubes filled, coated, or both filled and coated by a non-carbon material. |
| US08309225B2 |
Thermally conductive structural composite material and method
A heat dissipative composite material including a carbon fiber lay-up having a resin pyrolized to form a graphitic carbon laminate structure. A structural resin fills voids in the graphitic carbon laminate structure and provides strength to the graphitic carbon laminate structure. |
| US08309223B2 |
Polyimide based purge media and methods relating thereto
A method is disclosed for the manufacture of a powdered polyimide extrudate for use as a purge media. The method includes feeding a polyimide film material into an extruder having a first zone that provides heating and a subsequent second zone that provides endothermic shearing. In one embodiment, the resulting purge media comprises a sheared polyimide powder having an average particle size in a range of about 5 to 100 microns (or any sub-range thereof). The purge media can comprises up to 35 weight percent other additives. |
| US08309221B2 |
Reinforced foam panel
A reinforced panel comprises at least two strength-providing strands and an insulating filler wherein the filler is situated around the strands such that a combination of the strands and the filler form a cohesive structure. Additionally, a ratio of the strength-providing strands to the filler is such that the panel is strong and rigid and is capable of providing insulation. |
| US08309220B2 |
Coating for wood board and wood board
The invention relates to a coating for a wood board. In accordance with the invention, the coating is formed of at least three layers, which are the first (1) layer formed of a film containing polyolefin and a coupling agent which is reactive with —OH groups of the wood for forming self-adhesive properties, second (2) layer selected from the group signaling layer and decorative layer and third (3) layer formed of a film containing polyolefin and the coupling agent which is re-active with —OH groups of the wood for forming self-adhesive properties, and the second layer is arranged between the first and third layers, and the layers are joined together by means of the coupling agent. Further, the invention relates to a wood board (4) which has been coated by said coating. |
| US08309218B2 |
Lamination apparatus and methods
Components for the manufacture of polymer electrolyte membrane fuel cells are provided, as well as apparatus and automatable methods for their manufacture by rotary die cutting and by lamination of various layers to form membrane electrode assemblies. A method and apparatus for performing the method are provided comprising die-cutting webs of catalyst decal materials or electrode materials to make first and second workpieces at first and second rotary die stations; holding the die-cut workpieces by action of sub-ambient air pressure to an endless perforated belt of first and second vacuum conveyors, typically before they are fully cut from the first and second webs; transporting first and second workpieces to opposing sides of a membrane in a laminating station; concurrently feeding the first and second workpieces into the laminating nip adjacent to the membrane, and laminating the first and second workpieces to the membrane. |
| US08309216B2 |
Substrate having an electron donating surface with metal particles comprising palladium on said surface
The invention relates to a substrate with an electron donating surface, having metal particles on its surface, the metal particles including palladium and at least one metal selected from gold, ruthenium, rhodium, osmium, iridium, and platinum, wherein the amount of the metal particles is from about 0.001 to about 8 μg/cm2. A method of manufacturing the substrate including the steps a) depositing metal particles from a suspension of metal particles onto the substrate, b) rising and c) drying. |
| US08309213B2 |
Fire resistant flexible ceramic resin blend and composite products formed therefrom
A high-temperature heat resistant elastic composite comprising a porous high molecular-weight silicon polymer and a reinforcing material wherein the silicon polymer comprises a silicon resin, silica and boron oxide catalyzed by the boron oxide to form a reaction mass that is polymerized in acetone and to which the silica and boron nitride are added and wherein pores of silicone polymer are filled with a densification resin blend. |
| US08309211B2 |
Breathable non-asphaltic roofing underlayment
A non-asphaltic roofing underlayment that is breathable, water resistant and skid-resistant is disclosed. The non-asphaltic roofing underlayment includes a woven or non-woven substrate in which at least one surface thereof includes a breathable thermoplastic film disposed thereon. The breathable thermoplastic film imparts water-resistant to the substrate as well as maintains the breathability of the substrate. |
| US08309205B2 |
Single crystal diamond elements having convex surfaces and methods of its fabrication
A single crystal diamond element having a convex surface is disclosed, the convex surface including a spherical segment for which the maximum peak to valley deviation from a perfect spherical surface is less than about 5 μm. Alternatively or in addition, the RMS deviation from a perfect spherical surface may be less than about 500 nm, or the RMS roughness less than about 30 nm. A single crystal diamond element with a radius of curvature less than about 20 mm is also disclosed. In one aspect a single crystal diamond element having a conical half-angle greater than about 10° is described. The invention also provides a method for forming a rotationally symmetrical surface on a single crystal diamond element, comprising rotating the element about a first axis, applying a laser beam to the element in a direction perpendicular to the first axis, and translating the laser beam in two dimensions in a plane perpendicular to the direction of the beam. If the two-dimensional path follows the arc of a circle a spherical surface may be formed. The invention also provides improving a spherical surface on a single crystal diamond element by pressing a rapidly rotating cup onto a slowly rotating element. The element may be a lens, in particular a solid immersion lens. |
| US08309203B2 |
Water-soluble substrate with resistance to dissolution prior to being immersed in water
A water-soluble substrate, and more particularly a water-soluble substrate that is resistant to dissolution, and methods of making the same are disclosed. The water-soluble substrate has a first and second surface. Water-insoluble particles are applied to and partially embedded in at least one of said first and second surfaces, thereby forming protruberances on said first and/or second surface. The protruberances have an average height of from 10 nanometer to 100 micrometer, and the average distance between adjacent peaks of said protruberances is from 10 nanometer to 200 micrometer. Articles, such as pouches, made from the water-soluble substrate, are also disclosed herein. |
| US08309201B2 |
Symmetric, spatular attachments for enhanced adhesion of micro- and nano-fibers
A fabricated nano-structure includes a substrate, a supporting stalk, a node, and at least two spatular plate portions. The supporting stalk has a first end opposite a second end. The first end of the supporting stalk is connected to the substrate. The supporting stalk has a diameter range of about 50 nanometers to about 2 microns. A node is disposed at the second end of the supporting stalk. At least two spatular plate portions are connected to the node. The at least two spatular plate portions have planar geometries and are radially distributed about the node. The at least two spatular plate portions has a ratio of a maximum plate thickness to a maximum plate length of at most about 1:20. The maximum plate length is measured along a line from a boundary of the spatular plate portion to a centroid of the node. The maximum plate length is at least about 100 nanometers. The at least two spatular plate portion adhere to a contact surface using intermolecular forces when the spatular plate portions are in contact with the contact surface. |
| US08309193B2 |
Fluid transfer multi-layer tube based on a polyamide and an ethyl vinyl alcohol or polyvinyl alcohol
The present invention relates to a symmetrical multi-layer tube based on polyamide and ethyl vinyl alcohol (EVOH) or polyvinyl alcohol (PVOH) for transferring fluids. As examples of tubes for transferring fluids, mention may be made of fuel (gasoline, diesel fuel) pipes, in particular for carrying fuel from the tank to the engine of motor vehicles. Other examples of fluid transfer include, but are not limited to, the fluids used in fuel cells, CO2 systems for cooling, hydraulic systems, cooling circuits and air-conditioning circuits, and medium-pressure power transfer. |
| US08309189B2 |
Multilayered liquid container
A multilayered liquid container having a discharge port welded under specified conditions to a sealant, which is constituted of a resin comprising a cycloolefin resin as a main component. The discharge port is composed of: an innermost layer constituted of a resin comprising a cycloolefin as a main component; and a surface layer whose main part is constituted of a resin comprising a specific type of polyethylene as a main component. According to the present invention, there can be provided a multilayered liquid container, which can prevent an effective component of a content fluid from being adsorbed onto or penetrating through not only the container body, but also the resin constituting the discharge port, and enables high temperature sterilization treatment, coupled with the discharge port having high welded strength and drop strength. |
| US08309178B2 |
Corrosion resistant coating for steel
Provided are methods and initial structures for fabricating corrosion resistant steels that incorporate an aluminum rich corrosion resistant surface layer. The initial structures utilize layering and/or patterning for reducing the effective diffusion length Deff to a value well below the total thickness of the aluminum alloy protective layer X1 by providing vertical and/or lateral laminated structures that provide ready sources of Fe atoms during subsequent heat treatment processes. |
| US08309176B2 |
Manufacturing method of three-dimensional structure
A method for manufacturing a three-dimensional structure includes forming a first structure having a relief pattern on a substrate, forming a sacrifice layer on the first structure such that the sacrifice layer can be filled in a concave part of the first structure and the sacrifice layer can cover a surface of a convex part of the first structure on a side opposite to the substrate, forming a second structure having a relief pattern on the sacrifice layer, and a fourth step of removing the sacrifice layer from between the first structure and the second structure, and thereby bringing the second structure into contact with the surface of the first structure. |
| US08309174B2 |
Heteroleptic iridium precursors to be used for the deposition of iridium-containing films
The present invention provides a process for the deposition of a iridium containing film on a substrate, the process comprising the steps of providing at least one substrate in a reactor; introducing into the reactor at least one iridium containing precursor having the formula: XIrYA, wherein A is equal to 1 or 2 and i) when A is 1, X is a dienyl ligand and Y is a diene ligand; ii) when A is 2, a) X is a dienyl ligand and Y is selected from CO and an ethylene ligand, b) X is a ligand selected from H, alkyl, alkylamides, alkoxides, alkylsilyls, alkylsilylamides, alkylamino, and fluoroalkyl and each Y is a diene ligand, and c) X is a dienyl ligand and Y is a diene ligand; reacting the at least one iridium containing precursor in the reactor at a temperature equal to or greater than 100° C.; and depositing an iridium containing film formed from the reaction of the at least one iridium containing precursor onto the at least one substrate. |
| US08309173B2 |
System for controlling the sublimation of reactants
An apparatus and method improves heating of a solid precursor inside a sublimation vessel. In one embodiment, inert, thermally conductive elements are interspersed among units of solid precursor. For example the thermally conductive elements can comprise a powder, beads, rods, fibers, etc. In one arrangement, microwave energy can directly heat the thermally conductive elements. |
| US08309170B2 |
Multilayer nanocrystal structure and method for producing the same
Disclosed herein is a multilayer nanocrystal structure comprising a nanocrystal alloy core comprising two or more nanocrystals and including an alloy interlayer formed at an interface between the two or more nanocrystals, and one or more layers of nanocrystal shells formed sequentially on the surface of the nanocrystal alloy core, wherein the nanocrystal shells each have different band gaps. The multilayer nanocrystal structure can be applied to various electronic devices owing to its advantages of high luminescence efficiency, superior optical stability, and superior chemical stability. |
| US08309165B2 |
Color filter by copper and silver film and method for making same
The present invention discloses a color filter by copper and silver film, comprising: a lower copper layer; a lower silver layer formed on the lower copper layer; a medium formed on the lower silver layer; an upper copper layer formed on the medium; and an upper silver layer formed on the upper copper layer. |
| US08309162B2 |
Implant surface with increased hydrophilicity
A method of increasing the hydrophilicity of an implant to be implanted into living bone. The method comprises the act of depositing non-toxic salt residuals on the surface of the implant by exposing the surface to a solution including the non-toxic salts. The method further comprises the act of drying the implant. |
| US08309160B2 |
Method for modifying the flavor profile of a plant protein preparation
A method for modifying the flavor profile of a plant protein preparation, especially a protein preparation from a leguminous plant. The protein preparation is brought into contact with water-soluble carbohydrates in an aqueous solution before being added to a food product, the contact advantageously influencing the flavor profile of protein preparations from leguminous plant, so that the preparations can be used in foodstuffs without essentially changing the flavor thereof. |
| US08309157B2 |
Meat-containing, strip-shaped food product and method of making same
A flexible, strip-shaped food product is made by comminuting substantially frozen meat and heating the comminuted meat to at least partially denature the meat proteins and cooling the cooked meat. About 4% by weight to about 45% by weight of wheat flour is admixed with the cooked meat, along with other ingredients, to form a dough. Use of the wheat flour unexpectedly increases tensile strength of the dough and products baked from the dough, and maintains flexibility of the strip-shaped food products over an extended period of time. Cooking of the meat in the presence of salt unexpectedly increases water activity of the pieces, resulting in a product that has a skin and a moist middle, while maintaining tensile strength. The dough is rotary-molded into strip-shaped pieces. The rotary mold may have angled die cups. The strip-shaped dough pieces are then baked and dried. |
| US08309155B2 |
Vegetable and/or fruit drink composition
Provided is a drink containing vegetable juice and excellent in ease of drinking. A vegetable drink composition contains from 0.1 to 1.2 wt. % of (A) solids derived from vegetables and/or fruits, (B) an acidic polysaccharide water-soluble dietary fiber, and (C) water. |
| US08309154B2 |
Aerated food product with surface-active inorganic fibers
There is provided a surface-active material that comprises fibers which have been modified so as to impart surface-active properties onto said fibres and giving it a contact angle between 60° and 120°, wherein the fibres have an aspect ratio of more than 10 to 1,000. The surface-active material can be used for foam and emulsion formation and stabilization, coatings, encapsulation and drug delivery. It can for example be used in the following industries: foods, home and personal care, oilfield, agriculture, textile, construction, emulsion polymerization, leather, plastic, pulp, paper and pharma. |
| US08309153B2 |
Production of whole grain shredded products
Shredded whole grain products, such as ready-to-eat cereals, and sweet and savory snacks, such as whole grain shredded corn chips are continuously produced by pelletizing agglomerates of cooked, tempered, whole cereal grain particles. Cooked whole grains, such as corn and other non-gluten or low-gluten containing grains have a tendency to become hard and rubbery after cooking during the cooling and tempering process. The pelletization results in the production of whole grain pellets having a soft, pliable texture, which are shreddable into continuous net-like sheets on a mass production basis. The pelletizing may be at a pressure of about 200 psig to about 600 psig, preferably from about 400 psig to about 500 psig. The pelletizing temperature may be controlled to provide a pellet temperature of about 80° F. to about 135° F., preferably from about 90° F. to about 110° F., upon exiting the pelletizer. |
| US08309142B1 |
Formulations and methods for preventing eyebrow hair loss
Compositions comprising from about 0.5 to about 40 percent by weight of black cohosh extract, from about 0.5 to about 20 percent by weight of nonionic surfactant, and from about to 40 about 99 percent by weight of hydroxylated solvent are effective in reducing and preventing eyebrow hair loss in patients undergoing chemotherapy. |
| US08309141B2 |
Herbal composition PHY906 and its use in chemotherapy
This invention provides herbal compositions useful for increasing the therapeutic index of chemotherapeutic compounds. This invention also provides methods useful for improving the quality of life of an individual undergoing chemotherapy. Furthermore, this invention improves the treatment of disease by increasing the therapeutic index of chemotherapy drugs by administering the herbal composition PHY906 to a mammal undergoing such chemotherapy. |
| US08309139B2 |
Microemulsions with adsorbed macromolecules and microparticles
Microparticles with adsorbent surfaces, methods of making such microparticles, and uses thereof, are disclosed. The microparticles comprise a polymer, such as a poly(α-hydroxy acid), a polyhydroxy butyric acid, a polycaprolactone, a polyorthoester, a polyanhydride, and the like, and are formed using cationic, anionic, or nonionic detergents. The surface of the microparticles efficiently adsorb biologically active macromolecules, such as DNA, polypeptides, antigens, and adjuvants. Also provided are compositions of an oil droplet emulsion having a metabolizable oil and an emulsifying agent. Immunogenic compositions having an immunostimulating amount of an antigenic substance, and an immunostimulating amount of an adjuvant composition are also provided. Methods of stimulating an immune response, methods of immunizing a host animal against a viral, bacterial, or parasitic infection, and methods of increasing a Th1 immune response in a host animal by administering to the animal an immunogenic composition of the microparticles, and/or microemulsions of the invention, are also provided. |
| US08309136B2 |
In vitro methods for evaluating the in vivo effectiveness of dosage forms of microparticulate or nanoparticulate active agent compositions
Disclosed are in vitro methods for evaluating the in vivo redispersibility of dosage forms of poorly water-soluble active agents. The methods utilize media representative of in vivo human physiological conditions. |
| US08309134B2 |
Modified calcium phosphate nanoparticle formation
The present disclosure relates to non-aggregating nanoparticles and their associated methods of preparation. The nanoparticles may have a surface and a size range of 1 nm to 999 nm, along with a zeta potential of −50 to 50 millivolts. A polycation and/or polyanion may be disposed on the nanoparticle surface. In addition, an active ingredient may be encapsulated within the nanoparticles or associated with the polycation or polyanion on the nanoparticle surface. |
| US08309130B2 |
Adsorbent for oral administration
An adsorbent for oral administration, characterized by comprising a spherical activated carbon, wherein a diameter is 0.01 to 1 mm, a specific surface area determined by Langmuir's adsorption equation is 1000 m2/g or more, and a diffraction intensity ratio, an R value, determined by an equation (1): R=(I15−I35)/(I24−I35) (1) wherein I15 is a diffraction intensity when a diffraction angle (2θ) of an X-ray diffractometry is 15°, I35 is a diffraction intensity when a diffraction angle (2θ) of an X-ray diffractometry is 35°, and I24 is a diffraction intensity when a diffraction angle (2θ) of an X-ray diffractometry is 24°, is 1.4 or more; and an adsorbent for an oral administration, characterized by comprising a surface-modified spherical activated carbon, wherein a diameter is 0.01 to 1 mm, a specific surface area determined by Langmuir's adsorption equation is 1000 m2/g or more, a total amount of acidic groups is 0.40 to 1.00 meq/g, a total amount of basic groups is 0.40 to 1.10 meq/g, and a diffraction intensity ratio, an R value, determined by equation (1) is 1.4 or more. The adsorbents for oral administration exhibit a useful selective adsorbability, that is, a less adsorbability of useful substances in a body, and a greater adsorbability of toxic substances. |
| US08309126B2 |
Dispersible bosentan tablet
The invention relates to dispersible tablets comprising the compound 4-tert-butyl-N-[6-(2-hydroxy-ethoxy)-5-(2-methoxy-phenoxy)-2-(pyrimidin-2-yl)-pyrimidin-4-yl]-benzenesulfonamide. |
| US08309125B2 |
Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative
A pharmaceutical dosage form comprising a controlled release component comprising an antihyperglycemic drug in combination with a second component comprising a thiazolidinedione derivative is herein disclosed and described. |
| US08309124B2 |
Delayed release tablet with defined core geometry
A tablet comprising a core containing an active agent, and a coating, the core being disposed within the coating such that the coating has a thickness about a longitudinal axis (X-Y) of about 4.85 to 4.95 mm. The position of the core within the coating dictating that the active agent is released rapidly after a lag time during which time no active agent is released. |
| US08309119B2 |
Drug containing adhesive preparation
The present invention aims at providing an adhesive preparation wherein a drug is sufficiently dissolved in an adhesive layer and is not easily separated from the adhesive layer even during preservation of the adhesive preparation.The present invention provides an adhesive preparation having an adhesive layer on at least one surface of a support, wherein the adhesive layer comprises a first synthetic rubber having a viscosity average molecular weight of 1,600,000-6,500,000, a drug, an organic liquid component and a tackifier. The present invention further provides the aforementioned adhesive preparation, wherein the organic liquid component is contained in the adhesive layer in a proportion of 20 wt % or above relative to the total weight of the adhesive layer. |
| US08309118B2 |
Film forming compositions containing sucralose
Water soluble, gelatin-free dip coatings for substrates comprising a hydrocolloid, such as carrageenan, and sucralose. |
| US08309116B2 |
Personal care and cosmetics compositions comprising biologically-based mono and di esters
Personal care compositions comprising esters of 1,3-propanediol and acceptable carriers are provided. The esters can have at least 3% biobased carbon, and the compositions can further comprise 1,3-propanediol that is biologically-derived. Also provided are processes for producing personal care compositions comprising esters of 1,3-propanediol and acceptable carriers. The processes comprise providing biologically produced 1,3-propanediol, contacting the 1,3-propanediol with organic acids, which produces the esters, recovering the esters, and incorporating the esters into personal care formulations. Also provided are processes of making a personal care composition comprising providing an ester of 1,3 propanediol and mixing the ester with an acceptable carrier to form a personal care composition. |
| US08309115B2 |
Matrix, cell implantation and method for their production and use
The invention relates to porous matrices based on a biologically compatible polymer or polymer mixture, to a cell implantation that is established on said matrices and to additional cell implantation based on cell mixtures of hepatocytes and islets of Langerhans. The invention also relates to a method for producing porous matrices, to matrices obtained according to said method and to a special method for obtaining cells for the inoculation of an implantable matrix. |
| US08309113B2 |
Porous coating loaded with a liquid or a solid substance
The present invention relates to a process for manufacturing a porous coating with structures in the micro or nano-size domain characterized by the following steps:—providing a support having a surface,—depositing on the surface one mono-layer of temporary particles,—depositing a coating on the temporary particles in such a way that the thickness of the coating is less than the particle diameter,—eliminating the temporary particles and thereby obtaining a porous coating, the pores of the coating corresponding to the spaces previously occupied by the temporary particles and at least a part of the pores communicating with the external environment,—applying a coating fixation step, characterized by the fact that it furthermore comprise a filling step where the pores are at least partially filled with a liquid or solid substance. The invention also concerns a coating and an object which can be obtained with this process. |
| US08309103B2 |
Association of fluconazole-tinidazole for the treatment of vaginal infections, its composition, preparation process and usage
The present invention refers to a treatment for mixed infectious diseases in the human reproductive system, wherein an association of compounds containing fluconazole and either tinidazole or secnidazole is used, the same being associated in doses lower to those commonly used therapeutically. The combination has proven to be highly efficacious and shown a good degree of tolerance. |
| US08309100B2 |
Nucleic acids and polypeptides specific of the Neisseria genus pathogenic strains
The invention concerns nucleic acids coding for polypeptides specific of the Neisseria genus pathogenic strains, the corresponding polypeptides, and their diagnostic and therapeutic applications. |
| US08309099B2 |
DNA transfection system for the generation of negative strand RNA virus
The present invention is based on the development of a dual promoter system (preferably a RNA pol I-pol II system) for the efficient intracellular synthesis of viral RNA. The resultant minimal plasmid-based system may be used to synthesize any RNA virus, preferably viruses with a negative single stranded RNA genome. The viral product of the system is produced when the plasmids of the system are introduced into a suitable host cell. One application of the system is production of attenuated, reassortant influenza viruses for use as antigens in vaccines. The reassortant viruses generated by cotransfection of plasmids may comprise genes encoding the surface glycoproteins hemagglutinin and neuraminidase from an influenza virus currently infecting the population and the internal genes from an attenuated influenza virus. An advantageous property of the present invention is its versatility; the system may be quickly and easily adapted to synthesize an attenuated version of any RNA virus. Attenuated or inactivated RNA viruses produced by the present invention may be administered to a patient in need of vaccination by any of several routes including intranasally or intramuscularly. |
| US08309098B2 |
Recombinant modified vaccinia ankara (MVA) virus containing heterologous DNA inserts encoding human immunodeficiency virus (HIV) antigens inserted into one or more intergenic regions (IGRs)
The invention relates to novel insertion sites useful for the integration of HIV DNA sequences into the MVA genome, and to the resulting recombinant MVA derivatives. |
| US08309097B2 |
C-type lectin binding molecules, identification and uses thereof
C-type lectins are involved in the binding of many different types of carbohydrates. Considering their diversity in kind and expression of different types of cells, the influence of such binding is very diverse and dependent among others on the type of cell, the environment of the cell and the type of carbohydrate bound. In the present invention new carbohydrate specificities of C-type lectins are disclosed. Interference with this binding property has uses in the prevention of pathogen binding and also in influencing signaling pathways in the C-type lectin containing cell, particularly in Toll like receptor expressing cells such as dendritic cells. Also provided is the use of the carbohydrate specificity to enhance antigen presentation by antigen presenting cells and to manipulate migration of C-type lectin containing cells and the interaction of C-type lectin expressing cells with cellular ligands on neighboring cells. |
| US08309096B2 |
Fusion protein
Fusion proteins comprising an antigen derived from NY-ESO-1 linked to an antigen derived from LAGE-1, which may further comprise carriers, fusion partners, or the like, are provided. Methods for preparing, formulating, and using such fusion proteins are also provided. Such proteins are useful a vaccine components for inducing an immune response against a range of cancer-antigen-bearing cells. |
| US08309095B2 |
Parathyroid hormone receptor activation and stem and progenitor cell expansion
The invention relates to methods for manipulating hematopoietic stem or progenitor cells, mesenchymal stem cells, epithelial stem cells, neural stem cells and related products through activation of the PTH/PTHrP receptor in neighboring cells. |
| US08309092B2 |
Wise binding agents and epitopes
The present invention relates to binding agents for WISE, and includes for their manufacture and use. |
| US08309088B2 |
Method of treating osteoarthritis with an antibody to NGF
Methods are disclosed for treating osteoarthritis in a human subject in need thereof, comprising administering to the subject a therapeutically effective amount of an anti-human NGF antibody, or antigen-binding fragment thereof, wherein at least one symptom associated with osteoarthritis is prevented, ameliorated or improved. |
| US08309085B2 |
Engineered anti-IL-23R antibodies
Antibodies to human IL-23R are provided, as well as uses thereof, e.g. in treatment of inflammatory, autoimmune, and proliferative disorders. |
| US08309082B2 |
Anti-activin A antibodies and uses thereof
The disclosure provides compositions and methods relating to or derived from anti-activin A binding proteins, including antibodies. In particular embodiments, the disclosure provides fully human, humanized, and chimeric anti-activin A antibodies that bind human activin A, activin A-binding fragments and derivatives of such antibodies, and activin A-binding polypeptides comprising such fragments. Other embodiments provide nucleic acids encoding such antibodies, antibody fragments and derivatives and polypeptides, cells comprising such polynucleotides, methods of making such antibodies, antibody fragments and derivatives and polypeptides, and methods of using such antibodies, antibody fragments and derivatives and polypeptides, including methods of treating or diagnosing subjects having activin A-related disorders or conditions including cachexia related to gonadal cancer, other cancers, rheumatoid arthritis, and other diseases. |
| US08309077B2 |
Stabilized bacteriophage formulations
Stabilized bacteriophage compositions, and methods for preparing stabilized bacteriophage compositions are provided. The method for producing an antibacterial composition involves adsorbing an aqueous solution of one or more bacteriophages, or one or more phage components, onto a matrix to produce a composition, and drying the composition to produce the antibacterial composition. An antibacterial composition comprising one or more strain of bacteriophage, or one or more phage component, adsorbed onto a matrix is also provided. The antibacterial composition, or the antibacterial composition embedded in a solid support, may be used within a cream, lotion or gel, be admixed with a pharmaceutical carrier and administered topically, orally, nasally, used as a powdered inhalant, or the antibacterial composition or encapsulated antibacterial composition, may be added to a feed for animal, aquatic or avian uses. |
| US08309070B2 |
Use of umbilical cord blood stem cells to treat ischemic event
The invention relates generally to methods for isolation and culture of umbilical cord blood stem cells, cells isolated by the methods, and therapeutic uses for those cells. |
| US08309064B2 |
Skin care compositions comprising phenoxyalkyl amines
Skin care compositions comprising certain phenoxyalkylamines, which are particularly beneficial for skin lightening and achieving evenness of color, especially for face and underarm skin. |
| US08309061B2 |
Formulations and methods for treating rhinosinusitis
The invention involves methods and formulations for treating or preventing rhinosinusitis, including but not limited to, bacterial-induced, viral-induced and/or fungus-induced rhinosinusitis in mammals, and/or rhinosinusitis not induced by an infective agent, such as bacteria, fungus or virus. In one embodiment, the formulation of the present invention comprises an anti-inflammatory agent (e.g. fluticasone propionate) having a specific particle size distribution profile. The formulation may also comprise an antifungal agent, antibiotic or antiviral agent. |
| US08309057B2 |
Methods for elevating neurotrophic agents
Methods and systems are described that release one or both of a neurotrophin and an inhibitor of the degradation of the neurotrophin within or in the vicinity of a highly innervated tissue. In some embodiments, the method includes regulating the release of the neurotrophin and the inhibitor of degradation over time. In some embodiments, the method includes monitoring the concentration of the neurotrophin over time. The system may include a device or multiple devices for the release of the neurotrophin and the inhibitor as well as a controller. In some embodiments the system may include a sensor device and/or an imaging device capable of detecting the concentration of the neurotrophin over time. The release of the neurotrophin and inhibitor of degradation may be part of a controlled release system and regulated over time. |
| US08309055B2 |
PET radiotracers
The invention relates to novel 18F-labelled compounds which may be suitable for use as Positron Emission Tomography (PET) radiotracers, and to processes for preparation of such. The 18F-labelled compounds of the invention comprise a [18F]fluoroalkenyl group. |
| US08309047B2 |
Method and system for removal of carbon dioxide from a process gas
Disclosed is a method of removing carbon dioxide from a process gas, the method comprising: contacting an ammoniated solution with the process gas in an absorption arrangement 101, the ammoniated solution capturing at least a part of the carbon dioxide of the process gas, wherein the molar ratio, R, of ammonia to carbon dioxide in the ammoniated solution is controlled such that substantially no precipitation of solids occurs within the absorption arrangement 101; allowing ammoniated solution including captured carbon dioxide to exit the absorption arrangement 101; cooling the ammoniated solution that has exited the absorption arrangement, wherein at least a part of the captured carbon dioxide is precipitated as solid salt; separating at least a part of the precipitated salt from the ammoniated solution; heating the ammoniated solution from which the at least a part of the precipitated salt has been separated, such that substantially no solids are present in the heated ammoniated solution; and allowing the heated ammoniated solution to re-enter the absorption arrangement 101. Disclosed is also a system for removal of carbon dioxide from a process gas. |
| US08309044B2 |
Exhaust gas treatment system including a thermoelectric generator
An after-treatment device for an automotive engine includes a substrate having a thermoelectric generation element disposed in an interior volume thereof. The substrate has a first end, a second end, and an outermost lateral dimension that defines an interior volume, and is configured to flow engine exhaust gas from the first end to the second end such that the flowing exhaust gas is in thermal contact with the thermoelectric generation element. |
| US08309038B2 |
Device with which a histological section generated on a blade of a microtome can be applied to a slide
A device for applying a histological section to a slide is described. The histological section is generated by a cutting action performed by a blade of a microtome. The device comprises a positioning device having a component that is rotatably mounted to a bearing and has a receptacle for receiving and holding the slide, wherein the positioning device is designed such that the slide received in the receptacle can be rotated about an axis of rotation of the rotatably mounted component. |
| US08309036B2 |
Method for separating viscous materials suspended from a pipette
A structure for holding sample-containing receptacles includes a cover with holes formed therein through which the receptacles can be accessed with a substance transfer mechanism, such as a robotic pipettor. When the transfer mechanism is inserted into and then withdrawn from a receptacle, a string of viscous material may be suspended from the mechanism. A viscous string removal element adjacent each opening engages the string of viscous material and dislodges the string from the mechanism when the mechanism moves in a prescribed path with respect to the removal element. A sample rack configured to hold receptacles and to be inserted into the structure below the cover includes a sample rack having receptacle-receiving pockets, each with a resilient element and a positioning feature for holding receptacles of varying sizes in a predetermined position within the receptacle receiving pocket, and a cover including features for preventing a receptacle from being pulled out of its receptacle-receiving pocket when the transfer mechanism is withdrawn from the receptacle. |
| US08309032B2 |
Catalytic converter apparatus
A catalytic converter apparatus for use in an exhaust system of an internal combustion engine includes a housing having a gas inlet and a gas outlet, and at least one catalytic substrate element disposed in the housing. The at least one substrate element is divided into a plurality of zones or sections, the zones at least partially separated from one another to inhibit heat flow. The zones can be at least partially separated with walls. The walls can include insulating material for reducing the mobility of heat radially outwardly. Each of the zones defines a generally separate flow passage connecting the inlet and outlet in fluid communication. The apparatus can heat more rapidly from a cold start compared with conventional catalytic converters. |
| US08309022B2 |
Reduced temperature sterilization of stents
Methods and systems for reduced temperature radiation sterilization of stents are disclosed. |
| US08309021B2 |
Corrosion management systems for controlling, eliminating and/or managing corrosion
The present invention generally relates to corrosion management systems designed to deliver corrosion protection and/or the management of corrosion to a top portion of an enclosure (e.g., storage tanks, cisterns, containers, etc.). In one embodiment, the present invention relates to corrosion management systems designed to deliver corrosion protection and/or the management of corrosion to a top portion, or roof portion, of an enclosure where such a system includes one or more dispensers designed to deliver at least one corrosion inhibitor to a system designed to protect a top portion of an enclosure (e.g., storage tanks, cisterns, containers, etc.). |
| US08309020B2 |
Semiconductor-based detection and decontamination system
A system and method for identifying and making quantitative determinations of different deposits on a portion thereof, determining that the deposit is a contaminant and decontaminating at least the portion of the system is disclosed. The system comprises a controller, a sensing portion and a decontamination portion. The controller contains information about at least one noncontaminant. The sensing portion communicates with at least the controller and the portion of the system and is adapted to detect the deposit. The decontaminating portion communicates with at least the controller and is adapted to decontaminate the portion of the system. |
| US08309019B2 |
Powder metal forging and method and apparatus of manufacture
A method of forming a powder metal forging, including the steps of: forming a preform including a sintered powder metal composition; inserting the preform in a die set having a bottom die and a top die, the die set defining a forge form therewithin, the die set being in a closed position wherein the top die is contacting the bottom die; and compressing the preform in the forge form using an upper punch and a lower punch, the compressing step resulting in a formed part. The closed die set minimizes or eliminates flash in the formed part, particularly in the contoured surfaces, which allows the forging to be through hardened by direct quenching after the forging operation, without the need to remove hardened flash from these surfaces. |
| US08309008B2 |
Separation in an imprint lithography process
Systems, methods, and processes for separating a template from a substrate retained on an air cavity chuck during an imprint lithography process. Generally, vacuum level provided by air cavity chuck may be controlled during conforming of polymerizable material between the template and the substrate and during separation of the template and the substrate. |
| US08309004B2 |
Method for producing a composite part
The subject of the invention is a method for fabricating a composite laminate part, consisting in coating a steel sheet of which the thickness is less than 0.65 mm, with an adhesive polymer film of which the thickness is at least 0.1 mm, in order to form a composite laminate steel sheet, and then forming this composite laminate sheet by drawing in order to obtain said composite part. |
| US08309001B2 |
Method of de-aerating a high-viscosity paste charge
A highly-filled paste, and a method and device of de-aerating and injecting the paste, the paste including: (a) a solid filler; (b) an organic binder, and (c) a residual gas, wherein the paste contains at least 80 volume-% of the solid filler and has a viscosity exceeding 100 kilopascal·seconds, wherein the filler, binder, and residual gas are intimately mixed so as to form a substantially homogeneous paste, and wherein a composition of the solid filler, binder, and residual gas is selected such that the homogeneous paste has: an average density greater than 98.5% of a Theoretical Maximum Density (TMD). |
| US08309000B2 |
Method for manufacturing microlens and method for manufacturing solid-state image sensor
A method for manufacturing a microlens includes forming a microlens by pressing a microlens mold having a reverse shape of a microlens formed therein on a microlens-forming film formed on a substrate to transfer the reverse shape of the microlens to the microlens-forming film. The microlens mold is formed by irradiating an inorganic resist film which is formed on a mold substrate with exposure light by relative two-dimensional scanning, and etching an exposed region of the inorganic resist film to form the reverse shape of the microlens. The irradiation intensity of the exposure light is adjusted to correspond to the depth of the reverse shape of the microlens from the surface of the inorganic resist film on the basis of profile data of the reverse shape of the microlens. |
| US08308998B2 |
Polarizing film, coating liquid, and image display
The polarizing film of the present invention contains the azo compound represented by the following general formula (I). In the general formula (I), Q represents a substituted or unsubstituted aryl group, X represents a cationic group, a nitro group, a cyano group, or a hydroxyl group, and M represents a counter ion. |
| US08308996B2 |
Chromene compound
A photochromic chromene compound which develops a color of a neutral tint, has high color optical density, a high fading speed and high durability, and has an indeno(2,1-f)naphtho(1,2-b)pyran structure represented by the following formula as the basic skeleton, wherein a sulfur-containing substituent selected from thiol group, alkylthio group, alkoxyalkylthio group, haloalkylthio group, cycloalkylthio group, arylthio group and heteroarylthio group is bonded to the 6-position and/or 7-position carbon atom(s). |
| US08308981B2 |
Phosphor and manufacturing method for the same, and light source
A phosphor, which is given by a general composition formula expressed by MmAaDdOoNn:Z, (wherein element M is at least one kind of element having bivalent valency, element A is at least one kind of element having tervalent valency selected from the group consisting of Al, Ga, In, Tl, Y, Sc, P, As, Sb, and Bi, element D is Si and/or Ge, O is oxygen, N is nitrogen, and element Z is at least one kind of element selected from rare earth elements or transitional metal elements, satisfying m>0, a>0, b>0 o≧0, and n=2/3 m+a+4/3b−2/3o), where a content of the element Fe is smaller than 200 ppm. |
| US08308978B2 |
Polymer matrix electroluminescent materials and devices
Photoluminescent and electroluminescent compositions are provided which comprise a matrix comprising aromatic repeat units and a luminescent metal ion or luminescent metal ion complex. Methods for producing such compositions, and the electroluminescent devices formed therefrom, are disclosed. |
| US08308972B2 |
Additive for polishing composition
The invention relates to an additive for polishing composition, which can ensure stable polishing properties. The additive for polishing composition contains one or more amine compounds and an alcohol. The one or more amine compounds contain a quaternary ammonium salt. When the one or more amine compounds are contained in high concentration, the occurrence of precipitation of the amine compound can be prevented by including the alcohol. |
| US08308971B1 |
Materials for battery electrolytes and methods for use
Described herein are materials for use in electrolytes that provide a number of desirable characteristics when implemented within batteries, such as high stability during battery cycling up to high temperatures high voltages, high discharge capacity, high coulombic efficiency, and excellent retention of discharge capacity and coulombic efficiency over several cycles of charging and discharging. In some embodiments, a high voltage electrolyte includes a base electrolyte and a set of additive compounds, which impart these desirable performance characteristics. |
| US08308968B2 |
Monolithic high aspect ratio nano-size scanning probe microscope (SPM) tip formed by nanowire growth
A scanning probe where the micromachined pyramid tip is extended by the growth of an epitaxial nanowire from the top portion of the tip is disclosed. A metallic particle, such as gold, may terminate the nanowire to realize an apertureless near-field optical microscope probe. |
| US08308967B2 |
Wet etched insulator and electronic circuit component
The present invention relates to an insulator as an insulating layer in a laminate which can inhibit dusting at the time of use, more particularly an electronic circuit component to which the insulator has been applied, particularly a wireless suspension. The insulator comprises a laminate of one or more insulation unit layers etchable by a wet process, the insulator having been subjected to plasma treatment after wet etching. The insulator exists mainly as an insulating layer in a laminate having a layer construction of first inorganic material layer-insulating layer-second inorganic material layer or a layer construction of inorganic material layer-insulating layer, and at least a part of the inorganic material layer has been removed to expose the insulating layer. |
| US08308964B2 |
Planarization method for media
A planarization process may planarize a media disk that has data trenches between data features and larger servo trenches between servo features. A filler material layer is deposited on the media disk and provides step coverage of the trenches. The filler material has data recesses over the data trenches and servo recesses over the servo trenches that must be removed to produce a planar media surface. A first planarization process is used to remove the data recesses and a second planarization process is used to remove the servo recesses. |
| US08308963B2 |
Etchant for etching metal wiring layers and method for forming thin film transistor by using the same
The present invention discloses an etchant for etching at least two different metal layers, the etchant comprising hydrogen peroxide (H2O2) and one of carboxylic acid, carboxylate salt, and acetyl group (CH3CO—). The present invention also discloses a method of fabricating a metal wiring on a substrate, the method comprising forming a first metal layer on a substrate, forming a second metal layer on the first metal layer, and simultaneously etching the first metal layer and the second metal layer with an etchant comprising hydrogen peroxide (H2O2) and one of carboxylic acid, carboxylate salt, and acetyl group (CH3CO—). |
| US08308961B2 |
Method of producing a mold for imprint lithography, and mold
In order to prevent occurrence of a residual film distribution dependent upon a pattern density of a mold, in producing the mold to be used for imprint lithography, by etching using a mask, use is made of a first mask M1 for forming a desired pattern to be formed on a surface of the mold, and a second mask M2 for partially covering the first mask such that the area covering openings of the first mask is made larger as an opening ratio of the pattern formed on the first mold surface is higher, thereby to make a volume of a recess of the mold in a given area; in which, after the mold is etched by the first mask, etching is further conducted by covering partially the first mask with the second mask without removing the first mask; or alternatively, the etching is conducted with the first mask and the second mask overlapped from the beginning, thereby to use the second mask as a mask for delaying the etching, for conduct the etching. |
| US08308959B2 |
Material separator
A material separator removes material such as sand from a fluid utilizing an inclined housing having a fluid flow inlet in a lower portion of the housing. Higher density material descends by gravity to a lower wall of the inclined housing and continues to travel down the lower wall portion to a lower section of the housing where it is removed. The remaining fluid which may contain a liquid and a gas is removed from the housing via an outlet at the upper portion of the housing. |
| US08308954B2 |
Methods for recovering a polar solvent from a fluid stream contaminated with at least one polar impurity
A method of removing a polar solvent from a fluid volume contaminated with at least one polar impurity, such as a free fatty acid, is provided. The method comprises providing a fluid volume that includes at least one polar impurity dissolved in at least one solvent. The fluid volume is contacted with an expanding gas to remove the at least one solvent. The expanding gas may be dissolved into the at least one solvent in the fluid volume to form a gas-expanded solvent. The immiscibility of the polar impurities in the gas-expanded solvent enables separation of the polar impurities from the gas-expanded solvent. After separation of the polar impurities, at least one of the temperature and pressure may be reduced to separate the solvent from the expanding gas such that the clean solvent may be reused. |
| US08308952B2 |
Ion chromatography system using catalytic gas elimination
A liquid chromatographic system is provided including catalytically combining hydrogen and oxygen gases in the chromatography eluent stream in a catalytic gas elimination chamber, to form water and thereby reduce the gas content in the eluent stream. Also, a liquid ion chromatographic system in which the effluent from the detector is recycled to a membrane suppressor and then is mixed with a source of eluent for recycle to the chromatographic column. |
| US08308950B2 |
Methods of dewatering algae for diesel blend stock production
Methods for selective extraction and fractionation of algal lipids and algal products are disclosed. A method of selective removal of products from an algal biomass provides for single and multistep extraction processes which enable efficient separation of algal components. Among these components are neutral lipids synthesized by algae, which are extracted by the methods disclosed herein for the production of renewable fuels. |
| US08308948B2 |
Methods of selective extraction and fractionation of algal products
Methods for selective extraction and fractionation of algal lipids and algal products are disclosed. A method of selective removal of products from an algal biomass provides for single and multistep extraction processes which enable efficient separation of algal components. Among these components are neutral lipids synthesized by algae, which are extracted by the methods disclosed herein for the production of renewable fuels. |
| US08308944B2 |
System and method for treating wastewater via phototactic heterotrophic microorganism growth
A wastewater treatment method includes the steps of supplying a wastewater influent having nutrients for a population of phototactic heterotrophic microorganisms to an aerated bioreactor. At least a portion of the nutrients is converted into the phototactic heterotrophic microorganism population. The wastewater influent and the phototactic heterotrophic microorganism population together form a bioreactor effluent that is transferred to a light clarifier. The bioreactor effluent is concentrated in the light clarifier to form a low-solids effluent and a high-solids effluent. The concentration is performed by inducing the population of phototactic heterotrophic microorganisms to phototactically self concentrate through exposure to a light having at least one of an intensity and a wavelength sufficient to cause the phototactic heterotrophic microorganism population to migrate away from a source of the light. The high-solids effluent is then dewatered to form a concentrated biomass paste. The low-solids effluent is further processed to form a treated water stream. |
| US08308940B2 |
Chromatography devices and methods
Provided are chromatography devices having a stationary phase that includes patchy particles having at least two different surface chemistries, such as Janus particles. Also provided are methods of separating at least one analyte out of a sample, where the method includes adding a sample having at least one analyte to a chromatography device that includes a stationary phase that includes a plurality of patchy particles. Further provided are methods that include packing a chromatography column with a plurality patchy particles having at least two different surface chemistries. Additional embodiments are disclosed. |
| US08308939B2 |
Efficient arrangement of membrane bioreactors
Flat-sheet membrane filter assemblies require open space around equipment to form a viable path for an internal recycle or roll pattern. Creating a dedicated roll pattern for individual filter assemblies is space intensive and imposes process constraints on tank dimensions. A hollow wall or series of pipes forms a recycle wall designed to consolidate roll patterns and reduces space requirements. The recycle wall is designed such that the structural components also serve as a mixed liquor distribution system for the necessary roll pattern. Fixed vertically oriented conduit and sectional channel pieces allow for easy access and removal of membrane filter assemblies installed side by side. Feeding mixed liquor, air and or influent to the bottom of filter assemblies via submerged conduit improves process efficiency when coupled with return channels spaced not more than 10 feet away and above assemblies. The system is particularly advantageous for flat-sheet membrane filter units used in SMBR applications but is adaptable to other technologies including tubular and hollow-fiber membrane filter assemblies. |
| US08308936B2 |
Heat pump-type hot-water supply device
A heat pump type hot water supply device is provided with a heat source side heat pump unit having a heat radiating heat exchanger that condenses refrigerant to radiate heat from the refrigerant. The hot water supply device is provided with a water tank that stores water, a water supply pipe that supplies water to the water tank from the outside, a water circulation pipe that is extended in a bypassing manner and circulates the water in the water tank from a bottom section to an upper section, a heat absorbing heat exchanger that is arranged on the water circulation pipe and connected to the heat radiating heat exchanger of the heat source side heat pump unit so as to absorb heat, and a hot water supply unit that comprises a hot water supply pipe that supplies warm water in the upper section of the water tank to the outside. |
| US08308932B2 |
Method of recovering valuable metals from IZO scrap
Provided are a method of recovering valuable metals from IZO scrap, wherein indium and zinc are recovered as hydroxides by using an IZO scrap as both an anode and a cathode, and performing electrolysis while periodically reversing polarity; and a method of recovering valuable metals from IZO scrap, wherein the hydroxides of indium and zinc obtained by the electrolysis are roasted and indium and zinc are recovered as oxides. Specifically, provided is a method which enables the efficient recovery of indium and zinc from IZO scrap such as a spent indium-zinc oxide (IZO) sputtering target and IZO mill ends arising during the manufacture of such a sputtering target. |
| US08308930B2 |
Manufacturing carbon nanotube ropes
Techniques for manufacturing carbon nanotube (CNT) ropes are provided. In some embodiments, a CNT rope manufacturing method optionally includes preparing a metal tip, preparing a CNT colloid solution, immersing the metal tip into the CNT colloid solution; and withdrawing the metal tip from the CNT colloid solution. |
| US08308929B2 |
Microfluidic systems and methods for screening plating and etching bath compositions
Methods and systems for screening for the effect of bath composition on the performance of electroplating, electroless-plating, electrochemical-etching, electropolishing, and chemical-etching processes are provided. The methods and systems use microfluidic channels that allow for etching or plating studies on an electrode exposed to a multitude of bath compositions at different positions on its surface. After deposition or etching, the electrode surface can be quickly and easily detached from the device for analysis of deposited or etched film properties. |
| US08308928B2 |
Thrombosis filter with cover layer
A method is provided for applying a cover layer (9) to a net structure (4) to be used for medical purposes, in particular a thrombosis filter. The net structure (4) is applied to a planar substrate (1) that covers openings (5) of the net structure on one side, wherein the openings (5) across the uncovered side are filled with a sacrificial material (7), in particular copper. The net structure (4) is lifted from the substrate (1). A cover layer (9) is deposited on the surface previously covered by the substrate, and the sacrificial material (7) is removed. |
| US08308927B2 |
Electrofluidic textiles and cleaning implements using such electrofluidic textiles
The invention relates to textiles, reservoirs, or films which may be switchably rendered hydrophilic or hydrophobic for liquid wicking, repelling, moving, holding, absorbing, drying, wetting, dispensing, and other means of electrically manipulation of liquids. |
| US08308925B2 |
Gas sensor, control device thereof and method of measuring NOx concentration
A gas sensor for measuring NOx concentration in measurement gas based on sensor output depending on an amount of the detected oxygen includes an oxygen concentration control part for controlling oxygen concentration in the measurement gas. The oxygen concentration control part allows a control of oxygen concentration in the measurement gas to set at a designated value even after being mounted on an automobile, so that dependency of the sensor output with respect to oxygen concentration can be quantitatively detected. The sensor output for detecting NOx concentration is corrected by estimating an amount of a change accompanying the sensitivity degradation of the sensor output with respect to NOx concentration on the basis of a difference between oxygen output characteristics of the sensor output of an actually-used sensor and oxygen output characteristics of a sensor in the initial state, and correcting the sensor output in accordance with the amount of the change. |
| US08308920B2 |
Double contact bar insulator assembly for electrowinning of a metal
In various embodiments, the present invention provides an electrolytic cell contact bar having a first pole and a pair of second poles. The second poles are opposite in charge to the first pole and each of the pair of second poles are adjacent to and parallel to the first pole. In various embodiments, the contact bar may include an electrode holder capable of holding at least one electrode. |
| US08308916B2 |
Method for simultaneously coating a plurality of workpieces
This invention relates to a fixture for use in a physical vapor deposition coating operation which comprises a support structure 14 comprising a circular base member 10, a circular top member 11 opposite the circular base member 10, and a plurality of structural members 12 joining said top member 11 to said base member 10; a plurality of panel members 13 aligned in a vertical direction around the outer periphery of said support structure 14 forming a cylinder structure; said panel members 13 including a plurality of apertures for holding workpieces 19 and 35 to which a coating is to be applied; and said apertures positioned on said panel members 13 so that said workpieces 19 and 35 are aligned in a staggered vertical direction. This invention also relates to a method for simultaneously coating a plurality of workpieces 19 and 35, such as gas turbine compressor blades and vanes, with erosion resistant coatings using the fixture of this invention. |
| US08308914B2 |
Electrolytic ozone cell anode spring board fixture structure
An electrolytic ozone cell anode spring fastening board structure includes a solid polymer electrolyte membrane (1), an anode electrocatalyst layer (2), a diffusion layer (3), frame body and support parts (5). A diffusion layer counterpiece (4) has one side attached to the diffusion layer (3), the other side of the diffusion layer counterpiece (4) equipped with a centered elevated step, which contacts the center of the convex side of a spherical spring board (6). In addition, the solid polymer electrolyte membrane (1), frame body and support parts (5), diffusion layer (3), diffusion layer counterpiece (4) and spring board (6) are held together by mechanical fastening means. It prevents a decrease in ozone generation rate in electrolytic ozone cell that can occur from the metal board deformation and thinning of the anode electrocatalyst layer. This will enable the cell to maintain stable fasten strength and good contact of the metal board and anode catalyst in long term operation, achieving stable electrolytic ozone generation rate and cell performance. |
| US08308911B2 |
System and method for atmospheric carbon sequestration
This invention relates to systems and methods for converting biomass into highly inert carbon. Specifically, some embodiments densify the carbon into anthracite-style carbon aggregations and store it in geologically stable underground deposits. The use of certain embodiments yield a net effect of removing atmospheric carbon via the process of photosynthesis and converting it into hard coal, which can be stored in underground beds that mimic existing coal deposits which are known to be stable for thousands of years. |
| US08308910B2 |
Method for manufacturing press felt with seam, press felt, and base fabric
A method for manufacturing a press felt with a seam, to a press felt, and a base fabric of a press felt. The base fabric is a one-base structure with machine direction yarns forming seam loops and further machine direction yarns running in the web-side surface layer. The machine direction yarns weave with cross yarns. The yarn ratio of the surface layer machine direction yarns to the intermediate layer and further the bottom layer machine direction yarns is at least 2:1:1. In addition, the surface layer machine direction yarns have a long run and their cross-sectional area is smaller than the yarns forming the seam loops. |
| US08308908B2 |
Blade, structural components of a blade, and method for manufacturing a blade and the structural components of a blade
A blade, in which at least the composite base structure of the blade is manufactured in a pultrusion process by pulling fibers through at least an impregnation stage and a curing stage, the base structure is equipped with at least one wear area and the said blade is detached from a blade blank formed of a base structure and a wear area. The wear area of the blade is formed of an edge-structure part protruding outside the edge of the base structure. |
| US08308904B2 |
Printable product and a method for manufacturing a printable product
A printable product including a substrate including fibers. The substrate has a first side and a second side. At least one of the first side and the second side of the substrate includes a surface layer that does not substantially contain inorganic particles and forms an outermost surface layer of the substrate, which surface layer includes hemicellulose. A method for manufacturing a printable product and to a surface treating agent for treating a substrate including fibers. |
| US08308903B2 |
Process for the production of paper
The present invention relates to a process for producing paper which comprises: (i) providing an aqueous suspension comprising cellulosic fibers, (ii) adding to the suspension after all points of high shear: a first polymer being a cationic polymer having a charge density above 2.5 meq/g; a second polymer; and a third polymer being an organic or inorganic anionic polymer; and (iii) dewatering the obtained suspension to form paper. |
| US08308901B2 |
Enhanced fiber additive; and use
The disclosure provides a process of modifying a seed based fiber (SBF) to form an enhanced fiber additive (EFA). The process includes an acid treatment step and optionally at least one fiber modification step. Preferred EFA products and uses are described. |
| US08308900B2 |
Methods to control lipophilic extractives in acacia wood pulp and fiber
Methods to control lipophilic extractives in Acacia pulp and fibers are described. One method involves contacting the pulp or fibers with a composition containing at least one enzyme, such as at least one esterase or lipase or both, for a sufficient time and in a sufficient amount to control the lipophilic extractives present in the pulp or fibers. |
| US08308897B2 |
Plasma processing apparatus and plasma processing method
A plasma processing apparatus for processing an object to be processed using a plasma. The apparatus includes a processing chamber defining a processing cavity for containing an object to be processed and a process gas therein, a microwave radiating antenna having a microwave radiating surface for radiating a microwave in order to excite a plasma in the processing cavity, and a dielectric body provided so as to be opposed to the microwave radiating surface, in which the distance D between the microwave radiating surface and a surface of the dielectric body facing away from the microwave radiating surface, which is represented with the wavelength of the microwave being a distance unit, is determined to be in the range satisfying the inequality 0.7×n/4≦D≦1.3×n/4 (n being a natural number). |
| US08308893B2 |
Nano-oxide process for bonding copper/copper alloy and resin
A method of increasing adhesion between a copper or copper alloy layer and a polymeric resin. The method includes the steps of a) applying a pre-dip composition to the copper layer; b) applying a nano-oxide composition to the treated copper layer, c) applying a post-dip composition to the nano-oxide treated surface, and d) bonding a resin to the treated copper surface. The nano-oxide composition comprises (i) a chlorite; (ii) a caustic; (iii) a phosphate salt; (iv) an organic nitro compound; and (v) a thio compound. The post-dip composition is an alkaline solution that comprises (i) a phosphate salt; (ii) a source of molybdenum ions; and (iii) a thiazole. The process of the invention is useful for improving the bond between copper and a resin, including high Tg resins, halogen-free resins, and high speed/lost resins. |
| US08308892B2 |
Di-cinnamyl compounds and methods for use thereof
The invention generally relates to di-cinnamyl compounds useful in a variety of adhesive applications. More specifically, the invention provides chain-extended bismaleimides and methods for generating them by reaction with di-cinnamyl compounds, including particular di-cinnamyl compounds disclosed herein. Invention di-cinnamyl compounds can also be used as co-monomers in a Diels-Alder type cure, and can act as a co-monomer in a thermoset composition with a maleimide monomer. |
| US08308887B2 |
Via hole forming method using electrophotographic printing method
A via hole forming method and a multilayered board manufacturing method improve manufacturing yield by reducing the required processes. The via hole forming method includes a first step of forming a toner image by attaching toner particles, containing a conductive material and having a protruding portion, onto the surface of a first photosensitive member so that the protruding portion is directed to the outside; and a second step of opposing the surface of the first photosensitive member to one principal surface of a green sheet containing an insulating material and transferring the toner image to the one principal surface of the green sheet so that the protruding portions of the toner particles protrude into the green sheet so as to reach the other principal surface of the green sheet and the toner particles are buried in the green sheet. The via holes are formed using an electrophotographic printing method. |
| US08308880B2 |
Sign support
A sign support includes a mounting bracket and a sign holder. The mounting bracket selectively engages an associated fixture. The sign holder has a mounting bracket engaging member and a sign holding member that engages and holds a sign. An adhesive fastens the mounting bracket engaging member to the mounting bracket. The adhesive is an upstream adhesive such that the user receives the mounting bracket already bonded to the sign holder. |
| US08308878B2 |
Magnesium-based alloy wire and method of its manufacture
Magnesium-based alloy wire excelling in strength and toughness, its method of manufacture, and springs in which the magnesium-based alloy wire is utilized are made available. The magnesium-based alloy wire contains, in mass %, 0.1 to 12.0% Al, and 0.1 to 1.0% Mn, and is provided with the following constitution. Diameter d that is 0.1 mm or more and 10.0 mm or less; length L that is 1000 d or more; tensile strength that is 250 MPa or more; necking-down rate that is 15% or more; and elongation that is 6% or more. Such wire is produced by draw-forming it at a working temperature of 50° C. or more, and by heating it to a temperature of 100° C. or more and 300° C. or less after the drawing process has been performed. |
| US08308871B2 |
Thermal cleaning gas production and supply system
Methods and apparatus for cleaning undesired substances from a surface in a semiconductor processing chamber. An cleaning gas mixture is formed onsite and stored in a buffer tank for a time, prior to its introduction into a semiconductor processing chamber, to remove an undesired substance from a surface in the chamber. The undesired substance is removed without the generation of a plasma in the chamber, and at a temperature of less than 300° C. |
| US08308869B2 |
Automated heat exchanger tube cleaning assembly and system
An automated heat exchanger tube cleaning assembly and system are provided. The present system can automatically (without ongoing human intervention) survey the tube sheet of a heat exchanger in three-dimensions, convert and record the survey results as a digital file in three-dimensions, and then, according to sequential parameters input via custom software, automatically coordinate via computer one or more cleaning devices to effect the cleaning of each desired tube of the heat exchanger. |
| US08308868B2 |
Artificial field litter pick-up device
A device for cleaning an artificial “infill turf” field includes a rotating brush assembly and a basket for receiving waste and infill material. The basket has a bottom with openings that allow infill material to be returned to the field, and a vibrator to promote separation of infill from waste. The device may include wheels connected to the brush assembly in a manner effective to rotate the brush when one or both of the wheels rotate, and a magnet for picking magnetic waste material from the field. The device may include an actuator for adjusting the height of the brushes, and a tow bar that allows the device to be positioned in an “active” orientation to sweep a field, or an “uplifted” orientation to transport the device across curbs or rough terrain. Multiple brushes and/or baskets may be provided. |
| US08308864B2 |
Single-crystal manufacturing method
The present invention is a single-crystal manufacturing method based on the Czochralski method, comprising at least the steps of: producing a melt by heating and melting a crystalline raw material in a crucible with a heater; maturing the melt by keeping the melt at a high temperature; growing a single crystal after dipping a seed crystal into the matured melt, wherein the heater and the crucible are relatively moved up and down in the step of maturing. As a result, there is provided a single-crystal manufacturing method that enables the generation of dislocation to be effectively suppressed and a high quality single crystal to be manufactured at good yield, particularly in case of pulling the single crystal having a large diameter, in manufacture of the single crystal. |
| US08308861B2 |
Phase change material compositions
A phase change material (PCM) composition comprises a blend of at least one fatty acid ester and at least one ethylene copolymer, wherein the ethylene copolymer comprises at least 28% of an at least one polar comonomer by weight, based on the weight of the ethylene copolymer. A film or sheet comprises or is produced from the PCM composition and the film or sheet can be a single layer or multilayer structure. |
| US08308860B2 |
Laser-markable compositions
A laser-markable composition comprises a marking component and an organic compound, wherein the organic compound absorbs laser radiation at 780 to 2000 nm and thereby causes the marking component to change color, and wherein the organic compound has an absorptivity ratio, A r, of at least 1.25, wherein the absorptivity ratio is defined as formula (I): wherein: Ap780-2000 nm is an absorbance peak in the wavelength region of 780 to 2000 nm; and Aave600-700 nm is the average absorbance in the wavelength region of 400 to 700 nm. A y = A p 780 - 2000 nm A ave 400 - 700 nm ( I ) |
| US08308855B2 |
Filter element and filter unit
By providing a thin-type deodorizing filtering medium which can be mini-pleats-processed, a washing-regenerable filtering medium in which the deodorizing filtering medium and a dust collecting filtering medium are integrated and, further, a low pressure drop/dust collecting deodorizing filter unit which can be subjected to large air volume treatment are provided. A non-crimped single fiber having a specified Young's modulus and a specified fineness is used to prepare a nonwoven fabric sheet having high stiffness, and a gas adsorbing substance is adhered and fixed thereto. |
| US08308852B2 |
Gas adsorbing device, vacuum heat insulator making use of gas adsorbing device and process for producing vacuum heat insulator
A jacket material into which a gas adsorbing device and core material are inserted is decompressed in a vacuum chamber, the opening is sealed, and then the jacket material is exposed to the atmosphere. In the atmospheric pressure, a pressure of about 1 atm which is equivalent to the pressure difference between the inside and outside is applied to the jacket material of the heat insulator. The jacket material is made of a plastic laminated film and is deformed by pressure. A protruding portion is plunged into a container to drill through holes, and a gas adsorbent in the container communicates with the inside of the jacket material. Thus, both during holding and in applying to the vacuum heat insulator, the gas adsorbent can be applied to the vacuum heat insulator without degradation, and the high degree of vacuum can be kept for a long time. |
| US08308851B2 |
Removal of contaminants from water and gas by filtration
The invention relates to compositions and methods for separating oil and other contaminants (particularly oleophilic compounds) from water, gas and other carriers. The invention is useful for separating oil, including emulsified oil, from water and other oleophilic compounds from bilgewater and other wastewater. The compositions comprise a hydrocarbon resin and a drying oil, which may be combined in an organic solvent. For example, hydrocarbon resin and tung oil are optionally combined into a naphtha solvent. The invention is also useful for removing a variety of contaminants from an air stream, such as exhaust from internal combustion engines, burners, and other sources. |
| US08308849B2 |
Ultra cleaning of combustion gas including the removal of CO2
Ultra cleaning of combustion gas to near zero concentration of residual contaminants followed by the capture of CO2 is provided. The high removal efficiency of residual contaminants is accomplished by direct contact cooling and scrubbing of the gas with cold water. The temperature of the combustion gas is reduced to 0-20 degrees Celsius to achieve maximum condensation and gas cleaning effect. The CO2 is captured from the cooled and clean flue gas in a CO2 absorber utilizing an ammoniated solution or slurry in the NH3—CO2—H2O system. The absorber operates at 0-20 degrees Celsius. Regeneration is accomplished by elevating the pressure and temperature of the CO2-rich solution from the absorber. The CO2 vapor pressure is high and a pressurized CO2 stream, with low concentration of NH3 and water vapor is generated. The high pressure CO2 stream is cooled and washed to recover the ammonia and moisture from the gas. |
| US08308847B2 |
Filter for removing a sulfur-containing-gas and method for removing a sulfur-containing-gas using the same
Provided is a filter for removing a sulfur-containing-gas (1), which removes the sulfur-containing-gas by being brought into contact with the sulfur-containing-gas in a gas flow path, the filter including a former filter (11) disposed on an upstream side of the gas flow path, and a latter filter (12) disposed on a downstream side of the gas flow path, wherein the former filter (11) includes a first material for removing a sulfur-containing-gas, the first material including a porous support, and iodine which is supported on the porous support, and is produced by catalytic pyrolysis of ammonium iodide at a thermal decomposition ratio of 80% or more by use of the porous support as a catalyst, and the latter filter (12) includes a second material for removing a sulfur-containing-gas, the second material including an activated carbon fiber, and an alkali component which is supported on the activated carbon fiber. |
| US08308845B2 |
System and method for processing high purity materials
Systems and methods for processing high purity materials are disclosed. A unit operation processes a material stream, an operational parameter of the unit operation is monitored, and a standby unit is charged with pressurized gas to achieve system pressure. The material stream is diverted to the standby unit in response to the operational parameter of the unit operation registering a threshold value. Flow exiting the standby unit is first vented via an outlet, and then directed toward a point of use after the pressurized gas has been purged. The unit operation may then be serviced and subsequently brought back online. A second unit operation may process a second material stream simultaneously, and the second material stream may be periodically diverted to the standby unit in like manner, thus reducing line pressure variation. The disclosed method may be performed manually or implemented automatically through use of a controller. |
| US08308843B2 |
Method and device using pyrolysis for recycling used printed circuit board
A method and a device using pyrolysis for recycling used printed circuit board in which water (moisture) is introduced in the pyrolysis process and a fully sealed low pressure environment is established to ensure that no combustion happens in the pyrolysis process to enhance the safety of the process; pyrolysis gases generated in the process are concentrated and purified to provide useful fuels or chemical materials; therefore, the present invention can reduce process cost, improve recycling efficiency and provide processing device with high safety, thereby enhancing industry usability. |
| US08308839B2 |
Kimberlite based plant nutrient and preparation thereof
The present invention relates to provides novel fertilizer products from Kimberlite having utility as nutrients to supply silica, magnesium, trace elements with or without organic substances, and also having scope to design products with various combinations with other fertilizers and/or plant based nutrients with or without nano structure. |
| US08308823B2 |
Colouring composition
The present invention is related to an aqueous oxidative coloring composition for keratin fibers especially human hair. The inventors of the present invention have surprisingly found out that a composition comprising at least one oxidative dye precursor and optionally at least one coupling agent and at least one dipeptide colors hair excellently homogeneously especially hair with various level of damages and improves hair shine, combability and manageability and especially hair colored with such composition has less flyaways. |
| US08308819B2 |
Method for detecting the removal of a processing unit from a printed circuit board
Various methods for detecting the removal of a processing unit, such as a microprocessor or a microcontroller, form a printed circuit board in a secure printing system, such as a postage metering system are provided. The methods utilize one or more of a real time clock provided internal to the processing unit, a CMOS device provided on the printed circuit board external to the processing unit, and CMOS memory internal to the processing unit to detect the removal of the processing unit and therefore an attack. |
| US08308812B2 |
Prosthetic joint assembly and joint member therefor
A prosthetic joint member includes: a generally concave cup with an outer surface that is bone-implantable, the cup including a first indexing feature; a concave insert disposed inside the cup, the insert comprising a rigid material and including a concave interior defining a nominal surface, the interior including a cantilevered flange defined by an undercut in the insert, the flange defining a wear-resistant first contact surface which protrudes inward relative to the nominal surface, the insert including a second indexing feature. The first and second indexing features engage each other so as to retain the insert in a fixed angular orientation relative to the cup. |
| US08308810B2 |
Multiple bearing acetabular prosthesis
An acetabular prosthesis assembly can include an acetabular cup and a first liner. The acetabular cup can have an outer surface, an inner surface and an upper rim extending between the outer surface and the inner surface. The acetabular cup can have a cup connection portion including a groove formed on an upper face of the upper rim. The first liner can have an outer cup engaging surface and a liner connection portion that extends from a flange of the first liner. The liner connection portion can have a finger that is received by the groove formed on the upper face of the acetabular cup that selectively couples the liner connection portion with the cup connection portion in an assembled position. |
| US08308809B2 |
Method of implanting an implant including bone abrasion
An implant assembly having an articulating surface and an axial cavity arranged to receive an end of a bone, the axial cavity being generally circular in cross section in a plane normal to the axis of the implant, and including a spacing element detachable from the implant. At least a portion of the interior surface of the cavity is roughened and is arranged to abrade bone when the end of the bone is received in the cavity. The spacing element is arranged to prevent the implant from fully seating on the end of the bone such that the implant and the end of the bone are in a predetermined spaced apart arrangement. |
| US08308806B2 |
Orthopaedic stem with protrusion and associated surgical procedure
A first articulating member for use with a second articulating member to form a prosthesis for use in joint arthroplasty for a joint formed between adjacent first and second bones in which a bone fragment having an exterior surface has separated from the first bone is provided. The first articulating member includes an articulating portion having an articulation surface for articulation with the second articulating member and an attaching portion connected to the articulating portion for attachment to the first bone. The first articulating member also includes a fragment portion connected to at least one of the articulating portion and the insertion portion. The fragment portion includes a surface for contact with the external periphery of the bone fragment. |
| US08308805B2 |
Methods of delivering an implant to an intervertebral space
According to some embodiments, a method for promoting spinal fusion using a spinal implant comprises providing a spinal implant, wherein the spinal implant comprises an anterior wall, a posterior wall and two lateral walls configured to extend between the anterior wall and the posterior wall. In some embodiments, the spinal implant further comprises at least one internal chamber generally positioned between the anterior wall, the posterior wall and the two lateral walls, wherein the internal chamber being is adapted to receive at least one graft and/or other fill material. |
| US08308802B2 |
Expandable vertebral prosthesis
The present invention relates to an expandable prosthetic implant device for engagement between vertebrae generally comprising an inner member, outer member, and gear member positioned coaxial with respect to each other such that the inner and outer members are moveable relative to each other along an axis. The gear member is axially fixed to the outer member and freely rotatable with respect to the outer member and the gear member threadedly engages a threaded portion of the inner member to translate inner member along the axis. The implant is configured to engage the vertebrae in a predetermined alignment and the gear member includes gear teeth exposed to the exterior and configured to be accessible by a tool member at a plurality of angular positions around the perimeter of the implant device. |
| US08308792B2 |
Device for loading self-expanding stents
A device upon which a self-expanding stent may be crimped is utilized to safely load the self-expanding stent directly into a transfer tube or a delivery tube. The device comprises a compliant member, an expandable member, an expansion member and a retrieval member. |
| US08308791B2 |
Stent graft introducer
A stent graft introducer has a pusher, a nose cone, a region between the pusher and the nose cone for a stent graft, a sleeve extending over the pusher and proximally to the nose cone to cover the stent graft when retained in the region. An indwelling auxiliary catheter with a pre-curved proximal end is fitted into the introducer. The nose cone has an elongate groove and the auxiliary catheter has its proximal end in the elongate groove. In a partially retracted position of the sleeve the curved proximal end of the indwelling auxiliary catheter is exposed and uncovered by the sleeve and in an advanced position of the sleeve the curved proximal end of the indwelling auxiliary catheter is straightened, extends along the length of the groove in the nose cone and is covered by the sleeve. |
| US08308787B2 |
Rapid cooling of body and/or brain by irrigating with a cooling liquid
Methods and devices are disclosed for providing therapeutic hypothermia using irrigation of the aerodigestive tract with cooled liquids. The disclosed method provides much more rapid therapeutic cooling to lower temperatures than could previously be achieved, thereby improving clinical outcomes. Novel cooling liquids and cooling devices are disclosed for carrying out the method. An external turbulent flow of cooling liquid may also be applied to the exterior of the head to further promote heat exchange. Multiple embodiments of devices are disclosed for performing rapid induction and maintenance of therapeutic hypothermia either in a hospital setting or in the field so that hypothermic treatment can be quickly instituted before significant tissue damage occurs. Methods are also disclosed for targeting brain cooling by irrigating the upper airway/aerodigestive tract, and more generalized cooling by irrigating the esophagus and/or stomach. |
| US08308786B2 |
Methods and devices for non-invasive cerebral and systemic cooling via the nasal cavity
A method for cerebral and systemic cooling by circulating a cold liquid through a nasal catheter looped through the patient's nasal cavities and around the nasal septum. The nasal catheter is inserted into the patient's first nostril, advanced through the nasal cavity, around the nasal septum and out of the patient's second nostril. A cold fluid having a temperature between about −20° C. and about 37° C. is flowed though a lumen in the nasal catheter to cool the nasal cavity. The nasal catheter may have one or more flexible balloons mounted on the catheter such that when the catheter is looped around the nasal septum, the balloon(s) are positioned in a portion of the patient's first and second nasal cavities. When a cold liquid is circulated through the catheter lumen, the flexible balloons expand to a contact the inner walls of the nasal cavities and provide direct cooling of the nasal cavities. |
| US08308784B2 |
Low level light therapy for enhancement of neurologic function of a patient affected by Parkinson's disease
A method of treating a patient having neurologic function affected by Parkinson's disease is provided. The method includes providing a patient having neurologic function affected by Parkinson's disease. The method further includes delivering electromagnetic radiation noninvasively through the scalp and the skull of the patient to at least one portion of the brain of the patient. The light energy has a wavelength in the visible to near-infrared wavelength range, and the wavelength, power density, and amount of the light energy delivered to the at least one portion of the brain are sufficient to reduce the severity of symptoms of Parkinson's disease in the patient. |
| US08308782B2 |
Bone anchors with longitudinal connecting member engaging inserts and closures for fixation and optional angulation
Polyaxial bone anchors include a retainer for holding a shank within a receiver, the retainer being in at least two discrete pieces and cooperating with a variety of inserts, some of which independently lock the polyaxial mechanism. Polyaxial and mono-axial bone anchor assemblies include pivot and/or pressure inserts or pads that cooperate with longitudinal connecting members to provide a desired degree of continued control of angulation of the longitudinal connecting member in the sagittal plane or to hold the connecting member in place. Pressure pads for deformable rods may also be made from a deformable plastic material. |
| US08308780B2 |
Method for soft tissue attachment
An apparatus and method for fixing a selected graft relative to a selected anatomical portion. An anchor may be provided that may be interconnected with a selected graft portion that is operable to pass through a selected bore and then moved into an operable position to engage a selected portion of the bore to substantially eliminate the possibility of the graft moving in an unselected direction through the bore. |
| US08308772B2 |
Vertebral osteosynthesis equipment
Vertebral osteosynthesis equipment includes bony anchoring members, such as pedicular screws or hooks, at least one of which includes a proximal threaded stud for receiving a nut and a base portion for anchoring to a vertebra; linking rods, intended to be connected to these anchoring members and attached to the vertebrae by these anchoring members, parts for connecting these linking rods to the anchoring members, and extension pieces for engaging on the proximal stud(s) of the anchoring member(s) for running down connecting parts on this or these proximal stud(s) until they rest on the proximal zone(s) of the base portion(s) of the anchoring members. The proximal stud of at least one anchoring member and the extension piece intended to be used with this anchoring member include positioning elements for positioning the extension piece on the free end of the proximal stud, concentrically thereto. |
| US08308770B2 |
Dynamic stabilization system
The present invention relates to a dynamic stabilization system (DSS) having at least one rod having a ring formed therein (“the spring”) and a pair of pedicle screws adapted for fixation to separate vertebrae. |
| US08308767B2 |
Interlaminar stabilization system
A spinal stabilization system includes vertebral engagement members and an intermediate structure. The vertebral engagement members are configured to be disposed between a first vertebra and a second vertebra. The vertebral engagement members generally include seating surfaces for accommodating at least a portion of a laminar region of adjacent vertebra and are adjustable between an operable and inoperable configuration. The intermediate structure extends between the vertebral engagement members. The structural cooperation of the vertebral engagement members and the intermediate structure is such that the engagement members distract the adjacent vertebrae. |
| US08308765B2 |
Apparatus and methods for positioning and securing anchors
Apparatus and methods for positioning and securing anchors are adapted to be delivered and implanted into or upon tissue, particularly tissue within the gastrointestinal system of a patient. The anchor is adapted to slide uni-directionally over suture such that a tissue plication may be cinched between anchors. A locking mechanism either within the anchor itself of positioned proximally of the anchor may allow for the uni-directional translation while enabling the anchor to be locked onto the suture if the anchor is pulled, pushed, or otherwise urged in the opposite direction along the suture. This unidirectional anchor locking mechanism facilitates the cinching of the tissue plication between the anchors and it may be utilized in one or several anchors in cinching a tissue fold. |
| US08308764B2 |
Hyper-elastic needle
A method of arranging a surgical needle in an applicator. The needle is made of a hyper-elastic alloy which, after treatment, has two distinct states and includes a crimping zone for securing a suture to the needle, a free end having a tapered point which includes an inclined heel portion arranged on an inside portion of a curved profile. The method includes forcing the needle into a roughly elongated position when the needle is housed in an internal bore of the applicator. When the needle is not housed in an internal bore of the applicator, the needle adopts a curved profile as a result of superelasticity or hyper-elasticity of the needle. |
| US08308759B2 |
Single disc intraluminal fixation patent foramen ovale closure device
A device and method for deploying a mechanical closure device for closing a passageway in a body, for example a patent foramen ovale (PFO) in a heart. The single disc mechanical closure device is comprise of a distal and proximal anchor constrained by a closure line to facilitate mechanical closure by bringing the distal and proximal anchors into close proximity along the closure line. |
| US08308757B2 |
Hydraulically actuated robotic medical instrument
A hydraulically actuated medical instrument includes an elongated shaft having proximal and distal ends, a hydraulically actuated end effector at the distal end of the shaft and a fluid flow path extending through the shaft to the end effector. The end effector may be directly manually operated by way of a handle located at the proximal end of the shaft or remotely, for example, via robotic controller. Articulation joints may be provided along the shaft, between the shaft and end effector or handle, or elsewhere. The hydraulic actuation of the present invention permits multiple axis instrument articulation, miniaturization and simplified instrument fabrication. |
| US08308755B2 |
Elliptical retractor
A retractor for use in laparoscopic procedures includes an upper retractor ring, a lower retractor ring, and a retractor sheath extending between the upper retractor ring and the lower retractor ring to form a tubular passageway through which instruments or a medical practitioner's hands may pass during a medical procedure. The retractor sheath includes an elliptical passageway extending between lower retractor ring and the upper retractor ring. |
| US08308754B2 |
Embolic protection device
The embolic protection device (10) has an expandable tubular structure supporting a filter mesh material (12). The embolic protection device is compressed to a small diameter for insertion into a patient's aorta, then expanded within the aorta with the filter mesh material positioned to allow blood to enter sidebranch vessels connected to the aorta and to prevent embolic material from entering the sidebranch vessels. The filter mesh material may be configured with waves or undulations (26) for increased surface area and/or with two layers of mesh material to provide additional protection against embolization and to prevent inadvertent occlusion of the sidebranch vessels. |
| US08308752B2 |
Barrel occlusion device
An occlusion device for occluding a body vessel including a first hub having a tubular wall defining a lumen having a longitudinal axis and a second hub disposed distally along the longitudinal axis. A plurality of arcuate members extend between the first hub and the second hub. The arcuate members extend radially away from the longitudinal axis in an open configuration and extend substantially along the longitudinal axis in a closed configuration. A biocompatible material is disposed within a volume defined by the arcuate members to form an occlusive barrier when deployed within the body vessel. |
| US08308746B2 |
Method and apparatus for tissue morcellation
The invention relates to a tissue morcellator for minimally invasive surgery. The morcellator has a metallic cutting ring mounted on a visually transparent hollow cylinder, which in combination with a visually transparent outer morcellator tube enables a surgeon to visualize the inside of the morcellator shaft for detection of loose tissue fragments in the device. A tenaculum used with the morcellation device has a spacer for preventing contact with the blade. The cutting tube can oscillate, rather than rotate, along the longitudinal axis of the cutting tube. The morcellator utilizes an extendable tissue guide on the outer tube of the morcellator shaft for preventing the tissue from rotating along the longitudinal axis of the morcellator tube. This allows the tissue to be continuously rotated into the morcellator device for continuous peel. The tissue guide can also be fully retracted to allow for coring of the bulk tissue. |
| US08308743B2 |
Clipping device
The present invention provides a clipping device having a coil sheath inserted into an insertion tube in a back/forth movable way to allow it to be inserted into a body cavity, an operation wire inserted into the coil sheath in a back/forth movable way, and a clip directly connected to a distal end of the operation wire to allow it to clip a living tissue. |
| US08308738B2 |
Manually articulating devices
Methods and devices are provided for controlling movement of a working end of a surgical device, and in particular for performing various surgical procedures using an instrument having an end effector that can be articulated relative to an elongate shaft of the device. In certain embodiments, the end effector can also optionally rotate relative to the elongate shaft of the device, and/or the shaft can rotate relative to a handle of the device. |
| US08308732B2 |
Parallel drill guide
A parallel drill guide and system which maintains contact on the bone at various angles. The parallel drill guide comprises a fixed sleeve and a parallel, axially slidable, sleeve for guiding the insertion of two parallel wires or pins into bone at any angle while maintaining contact between the bone and the guide. The drill guide is also provided with a locking mechanism that locks the slidable sleeve into position at any lateral distance relative to the fixed sleeve, using a novel off-axis locking device. |
| US08308730B2 |
Method of and apparatus for determining the mechanical axis of a femur
The invention relates to a device for determining the mechanical leg axis of a femur. Said device is provided with a shaft (3) that comprises, on one of its ends, a securing device (5) that is connected to the shaft and that can be blocked at various angles, in order to obtain a fastening that can be blocked in an angle stable manner and that fastens the shaft (3) to the knee joint of a femur, and comprises a gripping element (10) on its other end. A force-torque measuring device (14) is arranged between the gripping element (10) and the shaft (3), said device enabling the longitudinal and/or transversal force components of force (Fz) exerted via the shaft (3) upon the knee joint to be measured by means of the gripping element (10) and/or torque produced thereby. The invention also relates to a method for determining the mechanical leg axis of a femur by means of the above mentioned device. The shaft (3) is fixed in its position by blocking at various angles, in particular an articulated connection when the measured transversal force components or torque produced thereby is minimized, in particular, is zero. |
| US08308728B2 |
Percutaneous vertebral stabilization system
The present invention relates to a system for percutaneously installing a vertebral stabilization system. A first anchor is positionable within a body of a patient through a first percutaneous opening and a second anchor is positionable within a body of a patient through a second percutaneous opening. A stabilization member is positionable within the body of a patient through the first percutaneous opening to engage and connect the first and second anchors. |
| US08308727B2 |
Flexible tooling for use in maxillary sinus elevation procedures and method of using the same
Tooling and methodologies for separation and dissection of the subantral membrane from the floor of the maxillary sinus, and for packing bone and bone substitutes under the subantral membrane. The tooling and associated methodology employ a handle and one or more support structures extending therefrom. A thin member extends from the distal end of the support structure(s). The thin member has a first peripheral region disposed opposite a second peripheral region. The first peripheral region is joined to or integrally formed with the distal end of the support structure(s). The second peripheral region defines a thin blade-like section for dissecting the subantral membrane from the floor of the maxillary sinus. In the preferred embodiment, the blade-like section is angled downward away from the distal support structure, which aids in positioning the blade-like section on the floor of the maxillary sinus. |
| US08308715B2 |
Cannula stabilizer
An apparatus and method for stabilizing a cannula to a vascular structure. The stabilizer includes a ring that circumferentially surrounds the cannula. Three or more struts extend distally from the ring and are outwardly-deflected by a first angle relative to a first axis that is parallel to a lengthwise central axis of the cannula. Each strut includes a contact pad that radially extends from the strut and is distally-deflected by a second angle relative to a second axis that is orthogonal to the first axis. Three or more arms extend proximally from the ring and each arm opposes one of the struts. The arms are inwardly-deflected by a third angle relative to the first axis. The stabilizer is configured to move relative to the cannula until the contact pads engage the vascular structure, causing the arms to engage and resist further movement of the stabilizer relative to the cannula. |
| US08308714B2 |
Control circuit and method for negative pressure wound treatment apparatus
A negative pressure wound therapy apparatus can include a wound dressing, a fluid collection container, a vacuum pump comprising a pump motor, and tubing. Additionally, the apparatus can include a pressure sensor that measures a pressure in the tubing. One or more tubes can channel a fluid between the wound dressing, the fluid collection canister, and the pump. In addition, first and second control circuits can be provided for controlling the pump motor without using a processor. The first control circuit can generate a difference signal between a desired pressure input and a pressure sensor input, and can further generate a motor control signal responsive to the difference signal. Moreover, a second control circuit can provide an override signal based at least in part on the difference signal and at least one reference signal. The override signal beneficially overrides the motor control signal to prevent the pump motor from stalling. |
| US08308711B2 |
Catheter shaft with a lubricious surface
A catheter which has an elongated shaft having a layer of an ultra high molecular weight polyolefin, such as a melt-extruded ultra high molecular weight polyethylene (UHMWPE). The UHMWPE, forming at least in part a surface of the shaft, facilitates sliding a blood/contrast coated device along the shaft surface, and preferably substantially prevents or inhibits agglomerations of blood and contrast from adhering to the surface of the shaft in a patient's body lumen. In a presently preferred embodiment, the layer has a lubricious coating, such that the coated surface of the UHMWPE layer significantly decreases the force produced by the blood/contrast coated device sliding along the coated surface. |
| US08308709B2 |
Endoluminal delivery of anesthesia
Described herein are methods and devices for selectively applying fluids (particularly anesthetics) to a target tissue from within a blood vessel while minimizing the amount of fluid applied to non-target tissue. The injection catheters described herein may include an elongate body, a directional injector, and one or more holdfasts for securing the catheter before extending the injector. The methods of selectively applying anesthetic to a target structure generally include the steps of inserting an injection catheter into a body vessel, positioning the injection catheter within the body vessel near the target structure, anchoring the injection catheter before extending a directional injector from the injection catheter, and applying anesthetic from the injection catheter to the target structure. |
| US08308706B2 |
Disposable diaper
In a disposable diaper, a ventral-side outer sheet and a back-side outer sheet are separated at a crotch portion, the back-side outer sheet has a main unit section that corresponds to joined sections in an up-down direction and a back-side extension section that extends below the back-side main unit section, the ventral-side outer sheet is composed of only a ventral-side main unit section that corresponds to the joined sections in the up-down direction, the back-side extension section has a central portion in the width direction overlapping the absorber and hip cover portions extending on both sides of the central portion in the back-side main unit section. |
| US08308703B2 |
Systems and methods for improved connection to wound dressings in conjunction with reduced pressure wound treatment systems
A system for applying reduced pressure to tissue includes a multi-lumen reduced pressure delivery tube having a proximate end, a distal end, a primary lumen extending through the conduit from the proximate end to the distal end, and an ancillary lumen extending through the conduit from the proximate end to the distal end. A vacuum pump is coupled to the proximate end of the primary lumen, and a reduced pressure adapter is coupled to the distal end of the reduced pressure delivery tube. The adapter includes channels to direct liquid away from the ancillary lumens and into the primary lumen. |
| US08308699B2 |
Layered non-fouling, antimicrobial antithrombogenic coatings
Substrates, optionally coated with an undercoating, having grafted thereto one or more non-fouling materials are described herein. The non-fouling, polymeric material can be grafted to a variety of functionalized substrate materials, particularly polymeric substrates and/or polymeric undercoatings immobilized on a substrate. The compositions described herein are highly resistant protein absorption, particularly in complex media and retain a high degree of non-fouling activity over long periods of time. The compositions described herein may also demonstrate antimicrobial and/or anti-thrombogenic activity. The non-fouling material can be grafted to a functionalized substrate, or optionally from an undercoating on the substrate, preferably without significantly affecting the mechanical and/or physical properties of the substrate material. |
| US08308698B2 |
Fluid driven medical injectors
Some injectors of the invention may include a fluid drive responsive to pressure of a working fluid (e.g., liquid, pneumatic, or both) to impart a sequence of forces to drive a delivery device (e.g., a syringe) to deliver a medical fluid (e.g., a contrast agent, a radiopharmaceutical, a drug, or a combination thereof). Some injectors may include a multimedia tube configured to pass a working fluid (e.g., air) and a light signal (e.g., infrared). Some injectors may include a peristaltic drive responsive to pressure of a working fluid. |
| US08308696B2 |
Needle sheathing device with flexible end-piece for syringe
The invention relates to a safe support device for a syringe, said support comprising a support sheath for the body of a syringe, and safety means which comprise an inner sheath suitable for sliding relative to said support sheath between a waiting retracted position, in which said inner sheath is substantially retracted inside said support sheath, and an active protection position, in which said inner sheath projects from said support sheath. The inner sheath has a free end portion formed by a flexible end-piece. The invention also relates to an assembly comprising such a safe support device and a syringe having a body, a piston and a needle disposed at one end of said body. |
| US08308689B2 |
Drive ram for medical injectors
A drive ram (26) for use with a medical fluid injector may include a central, longitudinal reference axis (24). First and second gripper members (92) may be pivotally interconnected with a plunger engaging end (266) of the drive ram. Each of the first and second gripper members may be pivotable about a common pivot axis (95) that intersects the reference axis. Each of the gripper members may further include a first end (102) that is remote from the common pivot axis. In some embodiments, the first and second gripper members may be pivotable between a first position and a second position. In the first position, the first ends of the gripper members may be spaced apart by a first distance, while in the second position, they may be spaced apart by a second distance that is greater than the first distance. |
| US08308688B2 |
Large-volume bolus patient controlled drug administration device
A patient controlled liquid drug administration device is provided that enables either or both of a continuous flow of a liquid drug, as well as successive, large-volume boluses thereof, to be self-administered to and by a patient while avoiding bolus refill during bolus delivery or after bolus delivery but before an intake stroke of the pump occurs. The device includes an elongated housing having an axial cavity extending through it with a reciprocating pump mounted at a bottom end thereof. The pump defines a closed internal reservoir and includes a first wall, or seat, that is fixed in the cavity, and a second, flexible wall that is axially movable in the cavity in relation to the fixed wall between reservoir-full and reservoir-empty positions. The pump includes an inlet port that is connectable to a source of a pressurized liquid drug by an inlet conduit, and an outlet port subcutaneously connectable to the patient by an outlet conduit, both conduits extending out the bottom end of the housing. An outlet clamp is mounted in the cavity to move between a closed position constricting the outlet conduit of the pump, thereby preventing the flow of the liquid drug through the outlet conduit, and an open position. An inlet clamp is mounted in the cavity to move between a closed position constricting the inlet conduit and thereby preventing the flow of liquid through it, and an open position disengaged from the inlet conduit, thereby allowing the flow of liquid through it. |
| US08308687B2 |
Injection set and injection assistance device
The present invention relates to an injection assistance device (1) for an injection device (3) comprising one body (2), one needle (7), and one piston plunger (26), characterized in that it comprises: a hollow sleeve (4) receiving the body (2), coupling arrangement (10) for moving the piston plunger (26) from an end-of-insertion position to an end of injection position the coupling arrangement being maintained in a passive state until the end-of-insertion position, spacer arrangement (8) to maintain the piston plunger (26) and the body (2) in an initial position, disengaging arrangement (22, 14, 15, 16) linked with the spacer arrangement (8), the spacer arrangement (8) and/or disengaging arrangement (22, 14, 15, 16; 25, 31) being arranged in order not to free the distal displacement of the piston plunger (26) before the one of the body (2). |
| US08308686B2 |
MEMS device and method for delivery of therapeutic agents
Embodiments of an implantable device for delivering a therapeutic agent to a patient include a reservoir configured to contain a liquid comprising the therapeutic agent, and a cannula in fluid communication with the reservoir. The cannula is shaped to facilitate insertion thereof into a patient's eyeball. |
| US08308685B2 |
Fluid collection device with captured retractable needle
A fluid transfer device includes a tube holder, a fluid container, a double ended needle with forward sharpened tip, and rearward sharpened tip. Fluid is withdrawn or injected into a patient from the tip, and into fluid contained. |
| US08308680B1 |
Selective alarms for an infusion device
An infusion system to administer a fluid includes an infusion pump with a pump processor, a pump memory to store a plurality of configurable alarms and a pump radio to enable bi-directional communication. The infusion system further includes a controller that has a controller processor, a controller memory, a controller radio to transmit and receive communication from the pump radio. The controller further has a graphical user interface shown on a display along with controls to manipulate the graphical user interface. Furthermore, the bi-directional communication between the infusion pump and the controller establish an infusion pump relative proximity between the infusion pump and the controller such that when the infusion pump relative proximity exceeds a pump threshold distance at least one of the plurality of configurable alarm conditions of the infusion pump is modified. |