Document Document Title
US08253032B2 Printed circuit board strip and panel
A printed circuit board strip and a printed circuit board panel are disclosed. In accordance with an embodiment of the present invention, the printed circuit board strip includes an unit area, a plating lead-in wire, which is for plating the unit area, and a mold gate, which is disposed on an outer side of the unit area. Here, the plating lead-in wire and the mold gate are electrically connected to each other through a lead line having a shape that is bent plural times. This can significantly save the production cost by preventing an excessive plated layer from being formed in an unnecessary area.
US08253029B2 Filter circuit element and electronic circuit device
A plurality of vias is disposed side by side on a multilayer board. A first via which is one of the vias disposed at one outer portion is electrically connected to a first outgoing line provided on the multilayer board. A second via at the other outer portion is electrically connected to a second outgoing line provided on the multilayer board. A plurality of the vias is connected to a first fixed potential layer (a ground layer, for example) of the multilayer board. At least one second fixed potential layer is provided, with a plurality of the vias through a clearance and having the same potential as that of the first fixed potential layer, as an inner layer of the multilayer board between the first and second outgoing lines and the fixed potential layer. Therefore, a BPF whose rate of occupied area is low is formed on the multilayer board without additional production processes.
US08253026B2 Printed circuit board
A printed circuit board is provided with at least one via hole, in which a heat dissipating element is arranged, wherein at least one radiant source is arranged on the heat dissipating element. The lighting device is provided with at least one such printed circuit board.
US08253023B2 Communication cable with variable lay length
Communication cables are provided in which a core lay length of the cable varies along the cable length. The cable may be provided with different segments that have different core lay lengths. It is desirable for neighboring core lay lengths in a cable to differ by a factor of two, to enable a reduction in power-sum alien near-end crosstalk (PSANEXT) when two cables are installed alongside one another. Segments of the cable having different core lay lengths may be spaced periodically along the length of the cable, and the periodicity of the spacing may be altered by a jitter distance. The introduction of jitter into the periodicity of the spacing of the segments increases the likelihood that a beneficial placement of core lay lengths will occur when two or more cables are installed alongside one another.
US08253022B2 Device and method for mechanically bonding and grounding painted cable trays
A suspension tray is provided that is adapted to hold a plurality of cables and/or wires that includes a device for electrically bonding and grounding the tray. The tray includes a series of spokes forming a wire mesh support on which the cables and/or wires are placed. The device (which serves to electrically bond and ground the tray) includes a plurality of conductive elements affixed to the wire mesh support. Each conductive element may include two side portions and a middle portion. The two side portions are preferably sealed with a paint composition and the middle portion includes a conductive surface that is capable of electrically bonding and grounding the tray.
US08253018B2 System and method for loop detector installation
A pre-fabricated ferromagnetic loop having a footprint characterized by a continuous wire shaped according to a predetermined planar pattern. In some embodiments, the predetermined planar pattern can be multiple contiguous polygons within a larger footprint used for establishing a sensor for the detection of moving vehicles. The footprint may include one of a triangle, a square, a rectangle, a rhombus, a parallelogram, an ellipse, or a circle, and/or other shapes or configurations. Similarly, each of the multiple contiguous polygons may include one of a triangle, a square, a rectangle, a rhombus, a parallelogram, and/or other shapes or configurations. A loop sensor housing is arranged to enclose a continuous loop sensor wire configured in the predetermined planar pattern. The prefabricated loop sensor is inserted in a groove web pre-cut in a receiving medium to match the predetermined planar pattern.
US08253007B1 Potentiometer control for musical instruments
A potentiometer control for use as a volume or tone control for a musical instrument, such as a guitar, that includes a switch which switches out the resistive element when the control is set to its most clockwise position so as to not load the instrument pickup when desired and so permit maximum volume to be achieved.
US08253005B2 Selecting device, selecting method, and information recording medium
A music information memory unit stores music information including identification information on each piece of music and pace information thereof. A process control unit selects out a predetermined number of pieces of music information each of whose identification information is to be presented from the music information memory unit. A notification image generating unit generates a notification image in which an object is moved in a scrolling manner based on the pace information of each piece of the selected music information. An image display control unit synthesizes the identification information of each piece of the selected music information with each of the generated notification images, and displays the synthesized image.
US08253003B2 Hinged drumstick
A percussion instrument is disclosed that may include a body having a longitudinal axis extending from a butt end to a striking end thereof and at least one hole extending along a transverse axis through the thickness of the body; a grasping mechanism having a first grip plate at a first end thereof and a second grip plate at a second end thereof, and a shaft extending through the hole in the body; and a compliance mechanism disposed between the first and second grip plates, enabling the first and second grip plates to be brought closer together in response to a compressive force applied to the grasping mechanism.
US08253001B1 Structure of drum with multiple uses
A structure of drum with multiple uses allows of being switched among multiple uses. The drum includes a shell which receives therein a slidable base board that carries thereon a multi-layered stack of cushioning pads and a detection sound collection board. The base board has opposite sides that are supported by slidable rod seats coupled to adjustable threaded rod, so that through rotation and adjustment of the threaded rods, upward movement of the base board is achieved to have the cushioning pad in contact engagement with a drum skin that reduces the sound generated by the drum so that the drum may serve as a practicing drum. Alternatively, the sound collection board is electrically connected to the electronic speaker, so that through controlled realized with a detection circuit board, an electronic drum is formed. For regular performance, the base board is separated from the skin to provide a regular drum.
US08252992B1 Inbred maize variety PH17RM
A novel maize variety designated PH17RM and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH17RM with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH17RM through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH17RM or a locus conversion of PH17RM with another maize variety.
US08252991B1 Inbred maize variety PH17R8
A novel maize variety designated PH17R8 and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH17R8 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH17R8 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH17R8 or a locus conversion of PH17R8 with another maize variety.
US08252986B1 Soybean cultivar 00174033
A soybean cultivar designated 00174033 is disclosed. The invention relates to the seeds of soybean cultivar 00174033, to the plants of soybean cultivar 00174033, to the plant parts of soybean cultivar 00174033, and to methods for producing progeny of soybean cultivar 00174033. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 00174033. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 00174033, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 00174033 with another soybean cultivar.
US08252984B1 Soybean variety RJS01001
According to the invention, there is provided a novel soybean variety designated RJS01001. This invention thus relates to the seeds of soybean variety RJS01001, to the plants of soybean RJS01001 to plant parts of soybean variety RJS01001 and to methods for producing a soybean plant produced by crossing plants of the soybean variety RJS01001 with another soybean plant, using RJS01001 as either the male or the female parent.
US08252980B2 GRG23 EPSP synthases: compositions and methods of use
Compositions and methods for conferring herbicide resistance or tolerance to bacteria, plants, plant cells, tissues and seeds are provided. Compositions include polynucleotides encoding herbicide resistance or tolerance polypeptides, vectors comprising those polynucleotides, and host cells comprising the vectors. The nucleotide sequences of the invention can be used in DNA constructs or expression cassettes for transformation and expression in organisms, including microorganisms and plants. Compositions also include transformed bacteria, plants, plant cells, tissues, and seeds. In particular, isolated polynucleotides encoding glyphosate resistance or tolerance polypeptides are provided. Additionally, amino acid sequences corresponding to the polynucleotides are encompassed. In particular, the present invention provides for isolated polynucleotides containing nucleotide sequences encoding the amino acid sequence shown in SEQ ID NO: 31, or the nucleotide sequence set forth in SEQ ID NO: 30.
US08252979B2 Manipulation of ammonium transporters (AMTS) to improve nitrogen use efficiency in higher plants
The present invention provides polynucleotides and related polypeptides of the protein AMT. The invention provides genomic sequence for the AMT gene. AMT is responsible for controlling nitrogen utilization efficiency in plants.
US08252976B2 Sugarcane plants with an increased storage carbohydrate content
The present invention relates to a method for increasing the storage carbohydrate content of sugarcane plants.
US08252973B2 Metabolic engineering of lipid metabolism by improving fatty acid binding and transport
CHI like fatty acid binding proteins and genes, recombinant cells and organisms, methods of metabolic pathway engineering to improve lipid production in cells, Crystal structures of CHI like fatty acid binding proteins, methods of engineering CHI like fatty acid binding proteins and systems thereof are provided.
US08252971B2 Systems and methods for protecting incisions
The present invention provides systems and methods for protecting wounds, such as surgical incisions. In one embodiment, a dressing for protecting a wound includes: a support cushion configured to surround the wound, the support cushion having sidewalls defining a major axis and a minor axis, the support cushion including at least two perforations that traverse the sidewalls at offset locations; a reservoir configured to be suspended over and in engagement with the support cushion; and a cover configured to be positioned over the reservoir. The at least two perforations may define first and second interlocking J-shaped portions. The support cushion may include a wicking portion configured to surround the wound and a hydrophobic portion configured to surround the hydrophobic portion. The wicking portion may be configured to transfer fluid from the wound to the reservoir. Methods of applying the dressing, and kits including the dressing, also are provided.
US08252970B2 Method and apparatus for hemostasis
Devices and methods are disclosed for achieving hemostasis in traumatized patients. Such haemostatic packing devices and methods are especially useful in the emergency, trauma surgery or military setting. In such cases, the patient may have received trauma to abdominal viscera, the thoracic cavity or the periphery. The devices utilize fluid impermeable outer surfaces and distributed pressure to achieve tamponade and hemostasis, primarily by exertion of pressure. The devices are flexible, bendable, and conformable in their wet or dry state so that they exert distributed pressure on the wound. Peripheral haemostatic packing devices include optional adhesive structures to attach one packing device to another. The hemostatic packing devices may be placed and removed by open surgery or laparoscopic access without generating excessive re-bleeding. The devices can be inserted into a wound and filled with fluid, gel, or particulates through an axially elongate tube to generate pressure to tamponade the wound.
US08252968B2 Process for producing a low volatility gasoline blending component and a middle distillate using an ionic liquid
A process for producing a low volatility gasoline blending component and a middle distillate, comprising alkylating a hydrocarbon stream comprising at least one olefin having from 2 to 4 carbon atoms and at least one paraffin having from 4 to 6 carbon atoms with an ionic liquid catalyst and an unsupported halide containing additive, and separating the alkylate into at least the low volatility gasoline blending component and the middle distillate, wherein the middle distillate is a fuel suitable for use as a jet fuel or jet fuel blending component. Also, a process for producing a gasoline blending component and a middle distillate, comprising adjusting a level of a halide containing additive provided to an ionic liquid alkylation reactor to shift selectivity towards heavier products, and recovering a low volatility gasoline blending component and the middle distillate. Also, processes comprising alkylating isobutane with butene over specific chloroaluminate ionic liquids.
US08252965B2 Method for separating halocarbons
The invention provides a method for separating halocarbons. In particular, a method for separating 2-chloro-1,1,1,2-tetrafluoropropane (HCFC-244bb) from 2-chloro-3,3,3-trifluoropropene (HCFO-1233xf) based on differences in melting points of these compounds. More particularly the invention pertains to a method for separating HCFC-244bb from HCFO-1233xf which are useful as intermediates in the production of 2,3,3,3-tetrafluoropropene (HFO-1234yf).
US08252964B2 Process for the purification of 2,3,3,3-tetrafluoro-1-propene (HFO-1234yf)
The subject of the invention is a process for the purification of 2,3,3,3-tetrafluoro-1-propene (HFO-1234yf). More particularly, it relates to a purification process in which 2,3,3,3-tetrafluoro-1-propene, comprising impurities based on halogen compounds, is brought into contact with an adsorbent, preferably molecular sieves and advantageously molecular sieves having a pore opening with an average diameter between 5 and 11 Å, preferably between 5 and 9 Å.
US08252962B2 Method for producing 1,2-propandiol by hydrogenating glycerine in a two-step reactor cascade
The present invention relates to a process for preparing 1,2-propanediol, in which a glycerol-containing stream, especially a stream obtained on the industrial scale in the production of biodiesel, is subjected to a hydrogenation in a two-stage reactor cascade.
US08252961B2 Method of producing lower alcohols from glycerol
This invention relates generally to a process for value-added processing of fats and oils to yield glycerol and glycerol derivatives. More particularly, the process converts glycerol to acetol and then acetol to propylene glycol to produce a propylene glycol with ultra-low amounts of ethylene glycol. The propylene glycol thus produced may be used as an antifreeze, deicing compound, or anti-icing compound.
US08252960B2 Process for manufacturing acrolein or acrylic acid from glycerin
The subject of the present invention is a process for preparing acrolein by dehydration of glycerin, characterized in that the dehydration is carried out in the presence of a catalyst comprising mainly a compound in which protons in a heteropolyacid are exchanged at least partially with at least one cation selected from elements belonging to Group 1 to Group 16 of the Periodic Table of Elements. The process according to the invention permits to obtain acrolein at higher yield.
US08252959B2 Preparation of α-hydroxy and α-amino ketones
A process for the preparation of an 1,1-disubstituted oxirane is disclosed, wherein an organic sulphide is reacted in a polar solvent with an educt containing a leaving group attached to a primary or secondary carbon atom, and/or the sulfonium salt formed in this way is reacted with a ketone in presence of a base and a polar solvent. Oxiranes of the type obtained may be further converted into the corresponding α-hydroxyketone or α-aminoketone, either in one step by subjecting to aerobic oxidation in the presence of a transition metal catalyst, or in two steps by hydrolyzation in the presence of an aqueous acid to the corresponding dialcohol and subsequent selective oxidation. Further described are some novel epoxide intermediates. The α-hydroxyketones and α-aminoketones thus obtainable are useful inter alga as photoinitiators.
US08252958B2 Use of guanabenz and its derivatives for making drugs for treating cystic fibrosis and diseases related to a protein addressing deficiency in the cells
The invention concerns the use of guanabenz and its derivatives for making drugs for treating cystic fibrosis and diseases related to a protein addressing deficiency in the cells, said derivatives corresponding to formula (I), wherein: R═H or C1 and the phenyl group comprises two substituents, or a pharmaceutically acceptable salt of said derivatives.
US08252954B2 Processes for the preparation of calixarene derivatives
A method for the preparation of calix[n]arene derivatives, in particular phosphonated calix[n]arenes. The present invention also relates to nano-structures of phosphonated calix[n]arenes.
US08252951B2 Process for the synthesis of (methoxy-1-naphthyl) acetonitrile and application in the synthesis of agomelatine
Process for the industrial synthesis of the compound of formula (I) Application of such process in the synthesis of agomelatine.
US08252948B2 Fat composition
The present invention relates to fat composition, more specifically relates to 60% to 99.9% by weight of diglyceride containing 0.1 to 89.9% by weight of conjugated linoleic acid; 0.001% to 0.2% by weight of banaba extracts fermented by microorganism such as Bacillus sp. or Aspergillus sp.; and the balance being monoglyceride, triglyceride or a mixture thereof.The fat composition of the present invention comprises fermented banaba extracts as an antioxidant, and the fat composition excels in oxidation stability and keeping stability, therefore the fat composition of the present invention may be widely used as cooking oil.
US08252946B2 Crystalline forms of tigecycline hydrochloride
The present invention relates to crystalline forms A and B of Tigecycline hydrochloride and to methods for the preparation of the same. Furthermore the present invention relates to the use of crystalline forms A and B of Tigecycline hydrochloride as intermediates for the formulation of an anti-infective medicament. Moreover the present invention relates to pharmaceutical compositions comprising crystalline form A of Tigecycline hydrochloride in an effective amount and to the use of crystalline form A of Tigecycline hydrochloride as anti-infective medicament.
US08252942B2 Substituted imidazoline compounds
The invention relates to compositions comprising substituted imidazoline compounds including prodrugs, and salts thereof. In some embodiments, the invention relates to the use of these compositions as therapeutic agents, preferably for the treatment of arthritis or cancer. In further embodiments, The invention relates to the pharmaceutical compositions with effective amounts of substituted imidazoline compounds disclosed herein that function as agonist or antagonists of the genetic expression or interactions with transcription factor NF-κB.
US08252940B2 5-substituted-2-imino-thiazolidinone compounds and their use as inhibitors of bacterial infection
A method for inhibiting Gram-negative bacterial pathogenesis, a method of screening for compounds that inhibit type III secretion in Gram-negative bacteria, and compounds that inhibit type III secretion in Gram-negative bacteria.
US08252936B2 Insecticidal compounds
Novel heteroaromatic compounds of formula (I): wherein A1, A2, A3, R1, R2, G1, G2, Q1 and Q2 are as defined in claim 1; or salts or N-oxides thereof. Furthermore, the present invention relates to processes for preparing compounds of formula (I), to insecticidal, acaricidal, molluscicidal and nematicidal compositions comprising them and to methods of using them to combat and control insect, acarine, mollusc and nematode pests.
US08252932B2 Modified carbocyanine dyes and their conjugates
Chemically reactive carbocyanine dyes incorporating an indolium ring moiety that is substituted at the 3-position by a reactive group or by a conjugated substance, and their uses, are described. Conjugation through this position results in spectral properties that are uniformly superior to those of conjugates of spectrally similar dyes wherein attachment is at a different position. The invention includes derivative compounds having one or more benzo nitrogens.
US08252931B2 Thiazolo[5,4-B]pyridine glucokinase activators
The present invention provides compounds of the formula which are activators of glucokinase activity and, thus, may be employed as therapeutic agents for the treatment of glucokinase mediated conditions. Accordingly, the compounds of formula (I) may be employed for the prevention and the treatment of impaired glucose tolerance, type 2 diabetes and obesity.
US08252930B2 Azaindole derivatives with a combination of partial nicotinic acetyl-choline receptor agonism and dopamine reuptake inhibition
Azaindole derivatives of formula (I): wherein the symbols have the meanings given in the specification, are described. These compounds have a combination of partial nicotinic acetylcholine receptor agonism and dopamine reuptake inhibition. The invention also relates to pharmaceutical compositions containing these compounds, to methods for preparing them, methods for preparing novel intermediates useful for their synthesis, methods for preparing compositions, and uses of such compounds and compositions, for example, their use in administering them to patients to achieve a therapeutic effect in disorders in which nicotinic receptors and/or dopamine transporters are involved, or that can be treated via manipulation of those receptors.
US08252929B2 8-carboxamido-2,6-methano-3-benzazocines
8-Substituted-2,6-methano-3-benzazocines of general structure I in which A is —CH2—OH, —CH2NH2, —NHSO2CH3, and Y is O, S or NOH are useful as analgesics, anti-diarrheal agents, anticonvulsants, antitussives and anti-addiction medications. 8-Carboxamides, thiocarboxamides, hydroxyamidines and formamides are preferred.
US08252926B2 Process for the preparation of imatinib base
Provided is an environmentally-friendly process for preparing imatinib base in high yield, without the use of an organic solvent.
US08252922B2 Method for crystallizing sucralose
The present application discloses a method for crystallizing sucralose, which uses an alcohol solvent or a mixed solvent of alcohol and other solvent(s) in the crystallization of sucralose.
US08252921B2 Method for the controlled oxidation of polysaccharides
The invention relates to a method for the controlled oxidation of oligo- and/or polysaccharides containing free —CH2OH primary hydroxyl groups, using an oxidizing agent. The invention is characterized in that the oxidation reaction is performed in a densified fluid which is inert in relation to the oxidizing agents employed. The invention is suitable for use, for example, in the food, paint, paper, textile, agricultural and pharmaceutical industries, in the medical, biomedical or paramedical fields, in the surgical field, in the cosmetic industry and as agents for the complexing or sequestering of metal ions, heavy metals and radioactive elements in the nuclear industry.
US08252920B2 Inosine derivatives and production methods therefor
The present invention provides a method for producing an inosine derivative represented by the following general formula (1) including the steps of subjecting an inosine derivative of general formula (3) to dithiocarbonylation and carrying out radical reduction of the obtained compound. According to the present invention there can be produced compounds useful as anti-AIDS drugs on industrial scale. wherein R1 may be the same or different and are each benzyl group, benzhydryl group or trityl group, each of which may have a substituent in general formulas (1) and (3).
US08252919B2 2′-hydroxy-protected ribonucleoside derivative and production method thereof
The present invention relates to a method for producing a 2′-hydroxy-protected nucleoside derivative by reacting a ribonucleoside with an acylating or a carbamoylating reagent in the presence of a metal complex consisting of a copper compound and an optically active ligand. By the method according to the present invention, a 2′-hydroxy-protected ribonucleoside derivative, which is an important intermediate for producing an oligonucleoside, can be easily produced with good regioselectivity from a nucleoside derivative of which 2′,3′-hydroxy groups are not protected.
US08252918B2 RNAi probes targeting cancer-related proteins
RNAi sequences that are useful as therapeutics in the treatment of cancers of various types, including prostate cancer, sarcomas such as osteosarcoma, renal cell carcinoma, breast cancer, bladder cancer, lung cancer, colon cancer, ovarian cancer, anaplastic large cell lymphoma and melanoma; and Alzheimer's disease. These sequences target clusterin, IGFBP-5, IGFBP-2, both IGFBP-2 and -5 simultaneously, Mitf, and B-raf. The invention further provides for the use of these RNAi sequences in the treatment of cancers of various types, including prostate cancer, sarcomas such as osteosarcoma, renal cell carcinoma, breast cancer, bladder cancer, lung cancer, colon cancer, ovarian cancer, anaplastic large cell lymphoma and melanoma; and Alzheimer's disease, and a method of treating such conditions through the administration of the RNA molecules with RNAi activity to an individual, including a human individual in need of such treatment.
US08252915B2 Human transferase family members and uses thereof
The invention provides isolated nucleic acids molecules, designated 33877, 47179, 26886, 46743, 27417, 32252, and 53320 nucleic acid molecules, which encode novel human transferase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 33877, 47179, 26886, 46743, 27417, 32252, or 53320 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 33877, 47179, 26886, 46743, 27417, 32252, or 53320 gene has been introduced or disrupted. The invention still further provides isolated 33877, 47179, 26886, 46743, 27417, 32252, or 53320 proteins, fusion proteins, antigenic peptides and anti-33877, 47179, 26886, 46743, 27417, 32252, or 53320 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
US08252914B2 Chimeric NK receptor and methods for treating cancer
The present invention relates to chimeric immune receptor molecules for reducing or eliminating tumors. The chimeric receptors are composed a C-type lectin-like natural killer cell receptor, or a protein associated therewith, fused to an immune signaling receptor containing an immunoreceptor tyrosine-based activation motif. Methods for using the chimeric receptors are further provided.
US08252909B2 Synthetic C-glycolipid and its use for treating cancer, infectious diseases, and autoimmune diseases
The invention is directed to compounds of formula (I) wherein X is O or NH; R′ is a hydrocarbon chain; R3 and R4 are hydrogen, OH or a monosaccharide; R5 is hydrogen or a monosaccharide; Q′ is optionally present and may be a C1-10 hydrocarbon; X′ is optionally present and may be O, S or NR8; and Q3 may be a hydrocarbon or hydrogen. The invention is also directed to the use of the compounds for treating cancer, infectious diseases and autoimmune diseases. The invention is also directed to syntheses of the compounds of formula (I).
US08252896B2 Process for making bivalirudin
The present invention relates to the efficient commercial synthesis of Bivalirudin.
US08252894B2 Poly-N-acetyl glucosamine (PNAG/dPNAG)-binding peptides and methods of use thereof
The present invention relates to peptides, particularly human monoclonal antibodies, that bind specifically to poly-N-acetyl glucosamine (PNAG), such as Staphylococcal PNAG, in acetylated, partially acetylated and/or fully deacetylated form. The invention further provides methods for using these peptides in the diagnosis, prophylaxis and therapy of infections by bacteria that express PNAG such as but not limited to Staphylococci and E. coli. Some antibodies of the invention enhance opsonophagocytic killing and in vivo protection against bacteria that express PNAG such as but not limited to Staphylococci and E. coli. Compositions of these peptides, including pharmaceutical compositions, are also provided, as are functionally equivalent variants of such peptides.
US08252892B2 Process for obtaining an elastomer in solid phase starting from its polymer solution
A process for obtaining an elastomer in solid phase from its polymer solution which comprises: (a) optionally pre-concentrating the polymer solution coming from the production system by a flash process; (b) subjecting the polymer solution to a concentrating stripping operation by water vapor in a mixing device comprising internal moveable mixing parts which transfer minimal mechanical energy to the solution in the form of friction heat; and (c) subjecting the concentrated polymer phase coming from (b) to devolatilization by mechanical energy and/or vapor flow to remove residual solvent.
US08252890B2 Benzoxazine-based monomer, polymer thereof, electrode for fuel cell including the same, electrolyte membrane for fuel cell including the same, and fuel cell using the same
A benzoxazine-based monomer, a polymer thereof, an electrode for a fuel cell including the same, an electrolyte membrane for a fuel cell including the same, and a fuel cell using the same. The aromatic ring may contain up to 2 nitrogens within the ring. Single ring and fused ring substituents are attached to the pendent nitrogen. The ring substituents may be heterocyclic.
US08252888B2 Process for continuous preparation of high molecular weight polyesters by esterification of dicarboxylic acids and/or transesterification of dicarboxylic acids with diols and/or mixtures thereof and an apparatus therefor
The present invention relates to a method for the continuous production of high-molecular polyesters by esterification of dicarboxylic acids and/or transesterification of dicarboxylic acid esters with diols and/or mixtures thereof in the presence of catalysts with formation of a prepolymer in a tower reactor and polycondensation thereof to form a high-molecular polyester in a polycondensation reactor, a prepolymer with >40 to 70 repeat units (DP) being produced in the tower reactor and this prepolymer being polycondensed in only one further reactor to form a polyester with >150 to 205 DP.
US08252881B2 Initiator integrated poly(dimethylsiloxane) and methods for making the same and its application
Disclosed herein is an initiator integrated polydimethylsiloxane (iPDMS). The iPDMS is a polydimethylsiloxane undergoing a hydrosilylation reaction. The initiator 10-undecenyl 2-bromo-2-methyl propionate is integrated on the surface of iPDMS by covalent bond. At % is 0.01-1% confirmed by X-ray photoelectron spectroscopy. Disclosed herein is a method for making an initiator integrated polydimethylsiloxane. Prepolymer A, cross-linker B and vinyl-terminated initiator C were mixed below a ratio of 10:1:4-0.01 for 6-24 hours, then the elastomer was formed. And, disclosed herein is functional surface modification of initiator integrated polydimethylsiloxane and its applications for biocompatibility, organic solvent compatibility and heat-sensitive materials.
US08252878B2 Polymer
A novel class of polymers obtainable by copolymerising a monomer mixture comprising (i) hydrophilic monomer of general formula (I) Y—B—X; (ii) styrene or a substituted styrene, a monomer or mixture of monomers which when polymerized form a polymer with a Tg lower than the Tg of a homopolymer of monomer (I) and lower than the Tg of a homopolymer of monomer (ii); and a monomer having a crosslinkable group is described. The invention also relates to a method for producing such polymers, implants coated with the polymers and methods for forming the same.
US08252875B2 Process for the preparation of unsymmetric bis(imino) compounds
Process for the preparation of monoimine compounds, wherein a dicarbonyl compound is reacted in an aliphatic, non-aromatic solvent with aniline. Monoimine compounds having electron-withdrawing substituents in the ortho position and unsymmetric bis(imino) compounds and unsymmetric iron complexes prepared therefrom and the use thereof in the polymerization of olefins.
US08252874B2 Ligands and catalyst systems for the oligomerization of olefinic monomers
The present invention relates to ligands and catalyst systems and a process for the simultaneous trimerization and tetramerization of olefinic monomers using said ligands, the ligands having the general formula (I): (R1)2P—P(R1)m(R2)n═N(R3)  (I) wherein R3 is selected from hydrogen, a hydrocarbyl group, a substituted hydrocarbyl group, a heterohydrocarbyl group, a substituted heterohydrocarbyl group, a silyl group or derivative thereof; the R1 groups are independently selected from an optionally substituted aromatic group bearing a polar substituent on at least one of the ortho-positions; and the R2 groups are independently selected from hydrocarbyl, substituted hydrocarbyl, heterohydrocarbyl and substituted heterohydrocarbyl groups with the proviso that when the group is aromatic it does not contain a polar substituent at any of the ortho-positions; with the proviso that m is 0 or 1, n is 1 or 2 and the total of m+n is 2.
US08252872B2 Polymer material containing chains bearing imidazolidone functions
The invention concerns a polymer material consisting of macromolecular chains bound by hydrogen bonds, wherein: the macromolecular chains consist of a polymer skeleton whereon is fixed by at least one covalent bond a modifying agent, the modifying agent comprising, assembled in a common molecule, one or more associative groups capable of being bound by hydrogen bonds and one or more reactive groups capable of forming covalent bonds with the polymer skeleton, at least one of the associative groups of the modifying agent is an imidazolidone heterocycle, the macromolecular chains bear on average, 1 to 10 imidazolidone groups per chain. The average number of imidazolidone groups to be introduced into the macromolecular chains depends both on the average mass of said chains and the final properties desired for the material.
US08252870B2 Cure system of halogenated elastomer compositions, a curable halogenated elastomer composition, and a method for curing halogenated elastomer compositions
The instant invention is a cure system for halogenated elastomer compositions, a curable halogenated elastomer composition, and a method for curing a halogenated elastomer composition. The cure system for halogenated elastomer compositions includes a polymercapto crosslinking agent, an inorganic base, and a combination of at least two or more of (a) a nitrogen containing chelating agent; (b) a first accelerator; or (c) a second accelerator. The curable halogenated elastomer composition includes a chlorinated elastomer, and a cure system including a polymercapto crosslinking agent, an inorganic base, and a combination of at least two or more of (a) a nitrogen containing chelating agent; (b) a first accelerator; or (c) a second accelerator. Furthermore, the method for curing a halogenated elastomer composition includes the following steps: (1) providing a chlorinated elastomer composition; (2) providing a cure system composition including a polymercapto crosslinking agent, an inorganic base, and a combination of at least two or more of (a) a nitrogen containing chelating agent; (b) a first accelerator; or (c) a second accelerator; (3) uniformly blending the cure system into the chlorinated elastomer composition; (4) thereby forming a curable chlorinated elastomer composition; (5) subjecting the curable chlorinated elastomer composition to heat or heat and pressure; and (6) thereby curing the curable chlorinated elastomer composition.
US08252869B2 Process for production of crosslinked poly(meth) acrylic acid nitroxide compounds
The present invention relates to a crosslinked poly(meth)acrylic acid nitroxide compound resulting from crosslinking of a poly(meth)acrylic acid nitroxide compound, and an object of the present invention is to provide a method of inexpensively and easily producing a crosslinked poly(meth)acrylic acid nitroxide compound having a high radical concentration.The present invention is a method of producing a crosslinked poly(meth)acrylic acid nitroxide compound including a repeating unit represented by the general formula (2): (in the formula, R represents a hydrogen atom or a methyl group), comprising a nitroxidation step carried out in a state that a crosslinked poly(meth)acrylic acid imino compound resulting from crosslinking of a poly(meth)acrylic acid imino compound including a repeating unit represented by the general formula (1): (in the formula, R represents the same group as that represented by R in said general formula (2)) is dispersed in water.
US08252868B2 Thermoplastic polymer composition and molded product
A thermoplastic polymer composition capable of exhibiting excellent impact resistance, durability and destaticizing property containing (A) 50 to 95% by mass of an aliphatic polyester-based resin and (B) 5 to 50% by mass of a block copolymer of (B1) a hard segment block with at least one of a polyamide, polyester, polyolefin or polyurethane, and (B2) a soft segment block having an ether bond.
US08252862B2 Silane coupling agents for filled rubbers
The invention describes a composition comprising a) a naturally occurring or synthetic rubber susceptible to oxidative, thermal, dynamic, light-induced and/or ozone-induced degradation, b) a white reinforcing filler, and c) as coupling agent, at least one compound of the formula I wherein the general symbols are as defined in claim 1, or an oligomeric hydrolysis product of the compound of the formula I.
US08252858B2 Low smoke density poly(arylene ether) compositions, methods, and articles
Thermoplastic compositions and methods of making the compositions are disclosed. The thermoplastic compositions include poly(arylene ether), a poly(alkenyl aromatic), an organophosphate ester flame retardant, a functionalized polysiloxane, and an organic acid. The thermoplastic compositions produce surprisingly low smoke density when burned, and they are useful for the fabrication of articles for the transportation and building and construction industries.
US08252855B2 Liquid color concentrate
A liquid color concentrate is disclosed, having a liquid acrylic-based polymer carrier; colorant; and optionally other functional additives. The colorant can be one or more pigments, one or more dyes, or combinations thereof. The liquid polymer is compatible with a variety of plastic resins, especially optically clear plastic resins, such as polycarbonate, polymethyl methacrylate, and styrene-acrylonitrile.
US08252854B2 Sulfonated or phosphonated latex polymers for ink-jet printing
The present invention is drawn to a latex particulate having a plurality of polymerized monomers and a dispersing agent incorporated therein. The dispersing agent can have the structure X—CH2(R)—SO3M, X—CH2(R)—PO3M2, or mixtures thereof, wherein X is SH, Cl or Br; R is independently C1 to C19 alkyl; and M is independently Li, Na, or K. The dispersing agent can comprise from about 0.1 wt % to about 20 wt % of the latex particulate.
US08252835B2 Compounds and methods for treating estrogen receptor-related diseases
Provided herein in certain embodiments are compounds, pharmaceutical compositions and methods for modulating the functions of estrogen receptor alpha 36, for preventing and/or treating diseases related to estrogen receptor alpha 36, for preventing and/or treating respiratory diseases such as asthma, for inducing cell death and/or inhibiting cell proliferation and for preventing and/or treating diseases involving abnormal cell proliferation such as cancers.
US08252833B2 Benzo (f) isoindol-2-ylphenyl acetic acid derivatives as EP4 receptor agonists
A compound of formula (I) or a pharmaceutically acceptable derivative thereof, wherein, R1 R2 R3, R4, R5, R6, X and Y are as defined in the specification; a process for preparing such compounds; a pharmaceutical composition comprising such compounds; and the use of such compounds in medicine.
US08252831B2 Imidazole-2-benzamide compounds useful for the treatment of osteoarthritis
The present invention provides compounds of the formula below or pharmaceutical salts thereof, wherein R1, R2 and R3 are as described herein; methods of treating osteoarthritis using the compounds; and a process for preparing the compounds.
US08252829B2 Aminopyrrolidinone derivatives and uses thereof
The present invention provides compounds of formula I: or a pharmaceutically acceptable salt thereof, wherein each of Ring A, Ring B, T, R2, R2′, and RA is as defined and described herein and methods for treating subjects or patients with a disease, disorder, or condition.
US08252826B2 Cyclopentyl- and cycloheptylpyrazoles
This invention relates to novel cyclopentyl- and cycloheptylpyrazole derivatives of the formula I wherein A and R1 to R4 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. The invention relates also to compositions including these compounds and methods of using the compounds.
US08252824B2 Substituted N-phenyl-bipyrrolidine carboxamides and therapeutic use thereof
The present invention discloses and claims a series of substituted N-phenyl-bipyrrolidine carboxamides of formula (I). wherein R, R1, R2, R3 and R4 are as described herein. More specifically, the compounds of this invention are modulators of H3 receptors and are, therefore, useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of diseases modulated by H3 receptors including diseases associated with the central nervous system. Additionally, this invention also discloses methods of preparation of substituted N-phenyl-bipyrrolidine carboxamides and intermediates therefor.
US08252820B2 1-orthofluorophenyl substituted 1,2,5-thiazolidinedione derivatives as PTP-as inhibitors
Compounds of the formula are inhibitors of protein tyrosine phosphatases (PTPases) and, thus, may be employed for the treatment of conditions mediated by PTPase activity. The compounds of the present invention may also be employed as inhibitors of other enzymes characterized with a phosphotyrosine binding region such as the SH2 domain. Accordingly, the compounds of formula (I) may be employed for prevention and/or treatment of insulin resistance associated with obesity, glucose intolerance, diabetes mellitus, hypertension and ischemic diseases of the large and small blood vessels, conditions that accompany type-2 diabetes, including hyperlipidemia, hypertriglyceridemia, atherosclerosis, vascular restenosis, irritable bowel syndrome, pancreatitis, adipose cell tumors and carcinomas such as liposarcoma, dyslipidemia, and other disorders where insulin resistance is indicated. In addition, the compounds of the present invention may be employed to treat and/or prevent cancer, osteoporosis, neurodegenerative and infectious diseases, and diseases involving inflammation and the immune system.
US08252818B2 Nicotinamide derivatives useful as P38 inhibitors
Compounds of formula (I): are inhibitors of p38 kinase and are useful in the treatment of conditions or disease states mediated by p38 kinase activity or mediated by cytokines produced by the activity of p38.
US08252816B2 Vanilloid receptor ligand compounds, pharmaceutical compositions containing them, a method of producing them and the use thereof to treat pain and various other conditions
Compounds corresponding to formula I: which act as vanilloid receptor ligands, pharmaceutical composition s containing such compounds, a method for producing the compounds, and the use of such compounds to treat pain and various other conditions.
US08252814B2 Agents and crystals for improving excretory potency of urinary bladder
Agents for improving potency of the urinary bladder which comprise an amine compound of non-carbamate-type having an acetylcholinesterase-inhibiting action. Particularly, crystals of a tricyclic, condensed, heterocyclic derivative are provided, which possess an excellent action to inhibit acetylcholinesterase and an action to improve the excretory potency of the urinary bladder. As an example, crystals of 8-[3-[1-[(3-fluorophenyl)-methyl]-4-piperidinyl]-1-oxopropyl]-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one or a salt thereof and pharmaceutical compositions containing them are disclosed.
US08252813B2 Salt and crystalline forms thereof of a drug
A crystalline form of a drug, ways to make it, compositions containing it and methods of treatment of diseases and inhibition of adverse physiological events using it are disclosed.
US08252812B2 Indazole inhibitors of the WNT signal pathway and therapeutic uses thereof
Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases due to mutations in Wnt signaling components. Also provided are methods for treating Wnt-related disease states.
US08252810B2 Bicycloamine derivatives
Compounds represented by formula (I) and pharmaceutically acceptable salts thereof have excellent sodium channel inhibitory action and are useful as therapeutic agents and analgesics for various kinds of neuralgia, neuropathy, epilepsy, insomnia, premature ejaculation and the like. wherein Q represents ethylene, etc., R1, R2 and R3 represent hydrogen, etc., X1 represents C1-6 alkylene, etc., X2 represents C1-6 alkylene, etc., A1 represents a 5- to 6-membered heterocyclic group, etc., and A2 represents C6-14 aryl, etc.
US08252808B2 Process and compounds for the production of (+)opiates
The invention generally provides processes and intermediate compounds useful for the production of (+)-opiates. Non-limiting examples of (+) opiates that may be derived from one or more compounds of the invention include (+)-noroxymorphone, (+)-naltrexone, (+)-naloxone, (+)-N-cyclopropylmethylnorhydrocodone, (+)-N-cycloproylmethylnorhydromorphone, (+)-N-allylnorhydrocodone, (+)-N-allylnorhydromorphone, (+)-noroxycodone, (+)-naltrexol, (+)-naloxol, and (+)-3-O-methyl-naltrexone.
US08252807B2 Methods of inhibiting the interaction between S100 and the receptor for advanced glycation end-products
A method of inhibiting an interaction between a S100 protein and the receptor for advanced glycation end-products is provided comprising administering to a subject a therapeutically effective amount of cromolyn, C5, or salt, hydrate, or solvate thereof. In some embodiments, the S100 protein is S100P. In some embodiments, the S100 protein is S100P. In addition, the present invention provides a method of treating a cancer comprising administering to a mammal a therapeutically effective amount of cromolyn, C5, or salt, hydrate, or solvate thereof. Additional methods are also provided.
US08252806B2 Potassium channel modulating agents and their medical use
This invention relates to novel potassium channel modulating agents, and their use in the preparation of pharmaceutical compositions.Moreover the invention is directed to pharmaceutical compositions useful for the treatment or alleviation of diseases or disorders associated with the activity of potassium channels, in particular respiratory diseases, epilepsy, convulsions, vascular spasms, coronary artery spasms, renal disorders, polycystic kidney disease, bladder spasms, urinary incontinence, bladder outflow obstruction, irritable bowel syndrome, gastrointestinal dysfunction, secretory diarrhoea, ischaemia, cerebral ischaemia, ischaemic heart disease, angina pectoris, coronary heart disease, traumatic brain injury, psychosis, schizophrenia, anxiety, depression, dementia, memory and attention deficits, Alzheimer's disease, dysmenorrhea, narcolepsy, Reynaud's disease, intermittent claudication, Sjorgren's syndrome, migraine, arrhythmia, hypertension, absence seizures, myotonic muscle dystrophia, xerostomi, diabetes type II, hyperinsulinemia, premature labour, baldness, cancer, immune suppression or pain.
US08252804B2 Selective proton coupled folate transporter and folate receptor, and GARFTase inhibitor compounds and methods of using the same
Fused cyclic pyrimidine compounds, including tautomers thereof, and pharmaceutically acceptable salts, prodrugs, solvates and hydrates thereof, are disclosed having the general Formula I: These compounds are useful in methods for treating cancer, selectively targeting cancerous cells via the proton coupled folate transporter, folate receptor alpha, and/or folate receptor beta pathways, inhibiting GARFTase in cancerous cells, and selectively targeting activated macrophages in a patient having an autoimmune disease, such as rheumatoid arthritis.
US08252803B2 Piperidine derivatives
Compounds of formula I: I selectively inhibit production of Ab(1-42) and hence find use in treatment of Alzheimer's disease and other conditions associated with deposition of A(b) in the brain.
US08252796B2 1-butyl-2-hydroxyaralkyl piperazine derivatives and the uses as anti-depression medicine thereof
The invention discloses 1-butyl-2-hydroxyl aralkyl piperazine derivatives and their use as antidepressants. The derivatives of the present invention have triple inhibition effect on the reuptake of 5-HT, NA and DA, and can be administrated to the patients in need thereof in form of composition by route of oral administration, injection and the like. Compared with clinically currently used dual targets antidepressants (such as venlafaxine), said derivatives may have stronger antidepression effect, broader indications, faster onset and lower neurotoxicity and side reaction; and said derivatives have stronger antidepression activity, lower toxicity, higher bioavailability, longer half life and better druggablity, compared with aryl alkanol piperazine derivatives and optical isomers thereof disclosed in prior art. The 1-butyl-2-hydroxyl aralkyl piperazine derivative is the free alkali or its salt of a compound of formula below:
US08252794B2 Composition for regenerative treatment of cartilage disease
A composition for regenerative treatment of cartilage disease, which comprises a PDE4 inhibitor as an active ingredient, specifically a composition comprising a PDE4 inhibitor and a biocompatible and biodegradable polymer is provided, which composition, when formulated into a form suited to administer locally to affected cartilage region, such as microsphere preparation, can provide a pharmaceutical composition showing an excellent effect in regenerative treatment of cartilage.
US08252791B2 Purine compounds as cannabinoid receptor blockers
The present invention relates to purine-based cannabinoid receptor blockers and pharmaceutical compositions thereof and methods of using the same for treating obesity, diabetes, dyslipidemias, cardiovascular disorders, inflammatory disorders, hepatic disorders, and a combination thereof.
US08252784B2 Photoactivable nitrogen bases
Base-polymerizable or base-crosslinkable compositions comprising select bicyclic amines with benzylic substitution undergo photochemically induced, base-catalysed reactions upon photochemical conversion of the benzylically substituted amine to an amidine derivative.
US08252783B2 Quinolone carboxylic acids, derivatives thereof, and methods of making and using same
A process of preparing a quinolone carboxylic acid or its derivatives having Formula I, Ia, Ib, or IV, as shown herein, comprises using a starting quinolone that already has one or more desired substituents at one or more particular positions on the quinolone ring and preserving the orientation of such substituents throughout the synthesis. The present process comprises fewer steps than prior-art processes. The present process also can include a simple separation of a desired enantiomer of the quinolone carboxylic acid or its derivatives from the enantiomeric mixture. Pharmaceutical compositions comprising fluoroquinolones prepared by the present process can be used effectively against a variety of microbial pathogens.
US08252782B2 Monocarbams
The invention relates to compounds of formula (I): wherein R1, R2, R3, R4, R5, and R6 as defined herein. The invention also relates to pharmaceutical compositions and methods of treating bacterial infections using compounds of formula (I).
US08252781B2 1,2-diazetidin-3-one derivatives and drugs containing same
[Object]It is to provide a novel compound useful for preventing and/or treating diseases that involves 11β-hydroxysteroid dehydrogenase 1 (in particular diabetes, insulin resistance, diabetes complication, obesity, dyslipidemia, hypertension, fatty liver, or metabolic syndrome).[Means to Solve the Object]A 1,2-diazetidin-3-one derivative represented by the following general formula (1) or salt thereof, or their solvate.
US08252780B2 Organometallic complexes as therapeutic agents
This invention comprises salophene-based metallic complexes. Included are metal-chelating analogues, and method of their preparation and use. These analogues have therapeutic activity including anticancer activity.
US08252772B2 Hyperthermic technologies and therapeutic uses thereof
The present invention provides nanoscale and microscale compositions useful for a variety of purposes, including the diagnosis and treatment of diseases. In one embodiment, the present invention provides a disease treatment system comprising a thermal induction agent and a radiation source, wherein the thermal induction agent comprises at least one carbon nanotube, at least one carbon microtube, or a mixture thereof.
US08252770B2 Compositions comprising glycosaminoglycans of low viscosity and use of said composition in therapy of chronic cystitis
The present invention concerns an aqueous pharmaceutical composition for bladder instillation, cystitis therapy, or interstitial cystitis therapy, the aqueous composition containing water, hyaluronic acid or a salt thereof and/or chondroitin sulphate or a salt thereof, and a pharmaceutically acceptable bivalent metal ion, wherein the bivalent metal ion is chosen from calcium and magnesium, and wherein the bivalent ion lowers the viscosity of the composition.
US08252765B2 Treatment of cancer by inhibition of IGFBPs and clusterin
Agents that reduce the amount of IGFBP-2 and/or IGFBP-5 and that are known to be useful in the treatment of cancer result in increased expression of the protein clusterin. Since clusterin can provide protection against apoptosis, this secondary effect detracts from the efficacy of the therapeutic agent. In overcoming this, the present invention provides a combination of therapeutic agents that is useful in the treatment of cancer. The combination includes an agent that reduces the amount of IGFBP-2 and/or IGFBP-5 and that stimulates expression of clusterin as a secondary effect, and an oligonucleotide that is effective to reduce the amount of clusterin in cancer cells. In some embodiments of the invention, the agent that reduces IGFBP-2 and/or IGFBP-5 is a bispecific antisense species. The oligonucleotide may be an antisense oligonucleotide or an RNAi oligonucleotide.
US08252763B2 RNAi therapeutic for treatment of hepatitis C infection
Small interfering RNAs (siRNAs) or small hairpin RNA (shRNAs) and compositions comprising same are provided that specifically target human cyclophilin A (CyPA) to effectively inhibit Hepatitis C(HCV) infection in a cell. Such siRNA and shRNAs may have a length of from about 19 to about 29 contiguous nucleotides corresponding to a specific region of human cyclophilin A (CyPA) cDNA of from about nucleotide 155 to about nucleotide 183 having particular potency against CyPA and HCV. Such siRNA and shRNAs may be formulated as naked compositions or as pharmaceutical compositions. DNA polynucleotides, plasmids, and viral or non-viral vectors are also provided that encode siRNA or shRNA molecules, which may be delivered directly to cells or in combination with known delivery agents, such as lipids, polymers, encapsulated lipid particles, such as liposomes. Methods for treating, managing inhibiting, preventing, etc., HCV infection using such siRNA and shRNAs and compositions comprising same are also provided.
US08252761B2 Method of increasing murine ES cell differentiation with PCL2
A method of suppressing undesirable cell proliferation, such as tumor growth, is provided comprising the step of increasing the level of PCL2 in target cells.
US08252760B2 Compositions and methods for diagnosing and treating melanoma
Described herein are compositions and methods for the diagnosis, prognosis, prevention and treatment of melanoma or melanoma associated symptoms. The compositions are microRNA molecules associated with melanoma, as well as various nucleic acid molecules relating thereto or derived therefrom.
US08252759B2 Methods and compositions for the treatment of eye disorders with increased intraocular pressure
The present invention relates to methods and compositions that decrease intraocular pressure (IOP) of the eye. The compositions of the invention comprise short interfering nucleic acid molecules (siNA) including, but not limited to, siRNA that decrease expression of genes associated with production or drainage of intraocular fluid. The compositions of the invention can be used in the preparation of a medicament for the treatment of an eye conditions displaying increased IOP such as glaucoma, infection, inflammation, uveitis, and diabetic retinopathy. The methods of the invention comprise the administration to a patient in need thereof an effective amount of one or more siNAs of the invention.
US08252755B2 Duplex oligonucleotide complexes and methods for gene silencing by RNA interference
Provided herein are duplex oligonucleotide complexes which can be administered to a cell, tissue or organism to silence a target gene without the aid of a transfection reagent(s). The duplex oligonucleotide complexes of the disclosure include a conjugate moiety that facilitates delivery to a cell, tissue or organism.
US08252754B2 Neuronal pain pathway
The present invention relates to the discovery of a novel molecular pathway involved in long-term hyperexcitability of sensory neurons, which, in higher animals, is associated with persistent pain. It is based on the discovery that, following injury to an axon of a neuron, an increase in nitric oxide synthase activity results in increased nitric oxide production, which, in turn, activates guanylyl cyclase, thereby increasing levels of cGMP. Increased cGMP results in activation of protein kinase G (“PKG”), which then is retrogradely transported along the axon to the neuron cell body, where it phosphorylates MAPKerk.
US08252747B2 Tissue adhesive sealant
A tissue adhesive sealant includes a cross-linkable protein in a solution that when combined with a cross-linking agent solution including an aldehyde and amino acid containing species reactive with the aldehyde cross-links to form a seal. The sealant is well suited for bonding tissue alone or in combination with a patch. The ratio between the aldehyde and the amino acid containing species is between 20:1 and 1:1 on an aldehyde moiety:amino acid or peptide subunit molar basis. Particularly strong seals are formed when the protein and cross-linking agent are present in a molar ratio of between 15:1 and 1:1.
US08252746B2 Anti-angiogenic agents and methods of their use
The present invention relates to the use of sFRP-4 and functional variants thereof as anti-angiogenic agents. It relates to methods of treatment and screening methods using sFRP-4 and functional variants thereof. Further, it relates to compositions, and in particular pharmaceutical composition, including sFRP-4 and functional variants thereof which may be used in the various methods provided herein.
US08252745B2 Methods for treatment of headaches by administration of oxytocin
The present invention relates to methods for the treatment of headache and headache disorders. The methods comprise administration of an oxytocin peptide for the treatment of primary and secondary headaches or trigeminal neuralgia.
US08252743B2 Modified erythropoietin polypeptides and uses thereof for treatment
Modified erythropoietin (EPO) polypeptides and other modified therapeutic polypeptides are provided. The EPO polypeptides and other therapeutic polypeptides are modified to exhibit physical properties and activities that differ from the unmodified EPO polypeptides and other unmodified therapeutic polypeptides, respectively. Nucleic acid molecules encoding these polypeptides also are provided. Also provided are methods of treatment and diagnosis using the polypeptides.
US08252742B2 Methods for enhancing the quality of life of a senior animal
Methods for enhancing the quality of life of a senior or super senior animal by feeding the animal a composition comprising at least one omega-3 polyunsaturated fatty acid and various combinations of amino acids, minerals, and antioxidants in amounts effective to enhance alertness, improve vitality, protect cartilage, maintain muscle mass, enhance digestibility, and improve skin and pelage quality. Changes in expression of genes associated with several biological pathways induced in an animal by feeding it said composition are consistent with an enhanced quality of life.
US08252736B2 Cleaning composition
An alkaline cleaning composition for use in aqueous medium comprising nanoparticles or a nanoparticles precursor and a polymeric nanoparticle stabilizer.
US08252728B2 Drilling fluids comprising hydroxylated polymers
Drilling fluids comprising polymers containing hydroxylated structural units are useful as accretion inhibiting agents, and/or as fluid rheology controlling agents, and/or as filtrate reducing agents, and/or as lubricating agents.
US08252726B2 Method for changing magnetisation of a superconductor
This invention relates to methods and apparatus for magnetizing a superconductor, in particular to flux pumps, and to new types magnetized superconductor. A method of changing the magnetisation of a superconductor, the method comprising automatically controlling a magnetic field to generate a wave of changing magnetic flux travelling over a surface of said superconductor.
US08252722B2 Controlling plant pathogens and pests with applied or induced auxins
The present invention is directed to methods for inhibiting the growth of disease organisms, particularly fungi and bacteria, on plant tissues. The present invention is also directed to methods for inhibiting the infestation of plants by insects and larva, particularly sucking and chewing insects. These methods are achieved by applying an auxin or a plant growth regulator (PGR) which will effect the level of auxin in the plant tissue to the seeds or tubers of the plant prior to planting or to the roots, foliage, flowers or fruit of the plant after planting.
US08252721B2 Herbicidal compositions
A description follows of compositions with a herbicidal activity containing the compound having formula (I), mixed with one or more known herbicidal products, possibly stabilized by the addition of at least one inorganic or organic base, and the relative use for the control of weeds in agricultural crops.
US08252718B2 Nutritive media for use in manufactured seeds
In one aspect, an improved nutritive media is provided that comprises from 10 g/L to 100 g/L of an adsorbent material, from 350 mg/L to 450 mg/L of NH4NO3, from 2000 mg/L to 3000 mg/L of KH2PO4, from 5 mg/L to 25 mg/L of FeSO4, from 600 mg/L to 1500 mg/L of MgSO4; and at least one component selected from the group consisting of: from 150 mg/L to 300 mg/L of Myo-inositol, from 1.5 mg/L to 3.0 mg/L of Thiamine-HCl, from 0.30 mg/L to 0.80 mg/L of Pyridoxine-HCl, from 1.5 mg/L to 3.0 mg/L of Nicotinic acid, from 0.15 mg/L to 0.30 mg/L of Riboflavin, from 0.75 mg/L to 2.0 mg/L of Ca-pantothenate, from 0.01 mg/L to 0.03 mg/L of Biotin and from 0.15 mg/L to 0.30 mg/L of Folic Acid. In another aspect, a manufactured seed is provided comprising the improved nutritive media.
US08252717B2 Dual-sided two-ply direct thermal image element
A dual-sided two-ply direct thermal image element is provided. In one embodiment, the dual-sided two-ply direct thermal image element comprises a first substrate having a first side and a second side, and a second substrate having a first side and a second side, wherein both the first substrate and the second substrate include a thermally sensitive coating on at least a first side thereof, and wherein the second side of the first substrate is releasably attached to the second side of the second substrate.
US08252716B2 Process for making porous activated carbon
A two-cycle thermal process for making porous activated carbon materials involves a first step of heating a mixture of a carbon precursor/chemical additive in a first heating cycle at a first temperature to cause gas liberation and volumetric expansion of the mixture, and heating the carbon material produced in the first step in a second heating cycle at a second temperature to carbonize and activate the carbon precursor. During the second cycle, essentially no gas liberation or volumetric expansion is observed.
US08252712B2 Polymer dispersant addition to fuel cell electrode inks for improved manufacturability
An ink composition for forming a fuel cell electrode includes a catalyst composition, a polymeric binder, a polymeric dispersant, and a solvent. The polymeric dispersant includes a perfluorocyclobutyl-containing polymer.
US08252711B1 Self supporting structurally engineered non-platinum electrocatalyst for oxygen reduction in fuel cells
A highly dispersed, unsupported, electrocatalyst made of pyrolyzed porphyries and a method for synthesizing the same. The disclosed synthesis procedure allows for optimization of pore size and therefore transport properties. Compounds suitable for use include transition metal N4-chelates such as, but not necessarily limited to, N4-chelates containing different metal centers including Co, Fe, Mn, Ni, Ru, Cu, etc., and other N4-chelates such as porphyrin, phthalocyanies, and structures based on their pyro products.
US08252708B2 Crystallization-free glass frit compositions and frits made therefrom for microreactor devices
A borosilicate glass composition suitable for manufacturing microreactor glass frits includes 12-22 mol % B2O3=12-22; 68-80 mol % SiO2; 3-8 mol % Al2O3, 1-8 mol % Li2O, and one of 0.5±0.1 mol % ZrO2 and 1.1±0.5 mol % F. After sintering a glass frit having the borosilicate glass composition, the glass frit has a surface crystalline layer of 30 μm or less or is amorphous throughout.
US08252705B2 Turf reinforcement erosion control mat
A bi-layer, woven geotextile fabric has interwoven first and second layers. The first layer is over and under woven through the second layer in a pre-determined pattern so that the first layer has portions which face a first side of the second layer and portions which face a second side of the second layer. Monofilaments in the warp direction of the first layer have a pre-determined differential heat shrinkage characteristic that is greater than the monofilaments in the warp direction of the second layer. Closed cells defined by the pattern of the over and under weave are disposed on the first and second sides of the second layer. Shrinkage of the monofilaments in the warp direction of the first layer provide for a separation of a portion of the second layer from the first layer at the cells.
US08252704B2 Additives to prevent degradation of cyclic alkene derivatives
This disclosure relates to compositions that include (a) at least one substituted or unsubstituted cyclic alkene, and (b) an antioxidant composition including at least one compound of Formula (I): R1 through R4 in Formula (I) are described in the specification.
US08252701B2 Method of manufacturing semiconductor device, method of processing substrate, and substrate processing apparatus
Provided is a method of manufacturing a semiconductor device. The method includes: (a) forming an oxide film having a predetermined thickness on a substrate by alternately repeating: (a-1) forming a layer containing a predetermined element on the substrate by supplying a source gas containing the predetermined element into a process vessel accommodating the substrate and exhausting the source gas from the process vessel; and (a-2) changing the layer containing the predetermined element into an oxide layer by supplying an oxygen-containing gas and an hydrogen-containing gas into the process vessel, wherein inside of the process vessel is under a heated atmosphere having a pressure lower than an atmospheric pressure; and exhausting the oxygen-containing gas and the hydrogen-containing gas from the process vessel; and (b) modifying the oxide film formed on the substrate by supplying the oxygen-containing gas and the hydrogen-containing gas into the process vessel, wherein the inside of the process vessel is under the heated atmosphere having the pressure lower than the atmospheric pressure, and exhausting the oxygen-containing gas and the hydrogen-containing gas from the process vessel.
US08252697B2 Zinc-tin oxide thin-film transistors
Methods of forming transparent zinc-tin oxide structures are described. Devices that include transparent zinc-tin oxide structures as at least one of a channel layer in a transistor or a transparent film disposed over an electrical device that is at a substrate.
US08252696B2 Selective etching of silicon nitride
Methods for etching dielectric layers comprising silicon and nitrogen are provided herein. In some embodiments, such methods may include providing a substrate having a dielectric layer comprising silicon and nitrogen disposed thereon, forming reactive species from a process gas comprising hydrogen (H2) and nitrogen trifluoride (NF3) using a remote plasma; and etching the dielectric layer using the reactive species. In some embodiments, an oxide layer is disposed adjacent to the dielectric layer. In some embodiments, the flow rate ratio of the process gas can be adjusted such that an etch selectivity of the dielectric layer to at least one of the oxide layer or the substrate is between about 0.8 to about 4.
US08252695B2 Method for manufacturing a micro-electromechanical structure
Disclosed herein is a method for manufacturing a micro-electromechanical structure. The method includes the following steps. A circuitry layer having a release feature is formed on an upper surface of a first substrate. A passive layer is formed on the circuitry layer without covering the release feature. The release feature is removed to expose the first substrate by a wet etching process. A portion of the exposed first substrate is anisotropically etched. A second substrate is disposed above the circuitry layer. A cavity is formed in the lower surface of the first substrate. The cavity is filled with a polymeric material. A portion of the first substrate under the microstructure is removed to release the micro-electromechanical structure.
US08252691B2 Method of forming semiconductor patterns
Semiconductor patterns are formed by performing trimming simultaneously with the process of depositing the spacer oxide. Alternatively, a first part of the trimming is performed in-situ, immediately before the spacer oxide deposition process in the same chamber in which the spacer oxide deposition is performed whereas a second part of the trimming is performed simultaneously with the process of depositing the spacer oxide. Thus, semiconductor patterns are formed reducing PR footing during PR trimming with direct plasma exposure.
US08252689B2 Chemical-mechanical planarization method and method for fabricating metal gate in gate-last process
The present invention provides a chemical-mechanical planarization method. The chemical-mechanical planarization method includes: providing a substrate including a gate and source/drain regions on the sides of the gate, the gate and the source/drain regions being overlay by an insulating layer, and the insulating layer including a protruding part above the gate and a recessed part above a surface of the substrate between gates; selectively doping the insulating layer such that only the protruding part is doped; and performing CMP on the substrate after doping, to remove the protruding part and planarize the surface of the substrate. By selectively doping the insulating layer, the method makes only the protruding part of the insulating layer doped, enhancing the corrosive attacks on the material of the protruding part by the slurry in the CMP, and increasing the removal rate of the material of the protruding part by the CMP.
US08252687B2 Barrier slurry for low-k dielectrics
The invention provides a chemical-mechanical polishing composition for polishing a substrate. The polishing composition comprises silica, a compound selected from the group consisting of an amine-substituted silane, a tetraalkylammonium salt, a tetraalkylphosphonium salt, and an imidazolium salt, a carboxylic acid having seven or more carbon atoms, an oxidizing agent that oxidizes a metal, and water. The invention further provides a method of chemically-mechanically polishing a substrate with the aforementioned polishing composition.
US08252684B1 Method of forming a trench by a silicon-containing mask
A method of forming a trench by a silicon-containing mask is provided in the present invention. The method includes providing a substrate covered with a silicon-containing mask. Then, anti-etch dopants are implanted into the silicon-containing mask to transform the silicon-containing mask into an etching resist mask. Later, the substrate and the etching resist mask are patterned to form at least one trench. Next, a silicon-containing layer is formed to fill into the trench. Finally, the silicon-containing layer is etched by taking the etching resist mask as a mask.
US08252673B2 Spin-on formulation and method for stripping an ion implanted photoresist
A spin-on formulation that is useful in stripping an ion implanted photoresist is provided that includes an aqueous solution of a water soluble polymer containing at least one acidic functional group, and at least one lanthanide metal-containing oxidant. The spin-on formulation is applied to an ion implanted photoresist and baked to form a modified photoresist. The modified photoresist is soluble in aqueous, acid or organic solvents. As such one of the aforementioned solvents can be used to completely strip the ion implanted photoresist as well as any photoresist residue that may be present. A rinse step can follow the stripping of the modified photoresist.
US08252669B2 Method for manufacturing microcrystalline semiconductor film by plasma CVD apparatus
An object of one embodiment of the present invention is to provide a technique for manufacturing a dense crystalline semiconductor film (e.g., a microcrystalline semiconductor film) without a cavity between crystal grains. A plasma region is formed between a first electrode and a second electrode by supplying high-frequency power of 60 MHz or less to the first electrode under a condition where a pressure of a reactive gas in a reaction chamber of a plasma CVD apparatus is set to 450 Pa to 13332 Pa, and a distance between the first electrode and the second electrode of the plasma CVD apparatus is set to 1 mm to 20 mm; crystalline deposition precursors are formed in a gas phase including the plasma region; a crystal nucleus of 5 nm to 15 nm is formed by depositing the deposition precursors; and a microcrystalline semiconductor film is formed by growing a crystal from the crystal nucleus.
US08252667B2 Laser processing method for semiconductor wafer
A laser processing method for a semiconductor wafer including a groove forming step of applying a pulsed laser beam having an absorption wavelength to the semiconductor wafer along a division line formed on the semiconductor wafer to thereby form a laser processed groove along the division lines on the semiconductor wafer, wherein the pulse width of the pulsed laser beam to be applied in the groove forming step is set to 2 ns or less, and the peak energy density is set in the range of 5 to 200 GW/cm2.
US08252663B2 Method of transferring a thin layer onto a target substrate having a coefficient of thermal expansion different from that of the thin layer
A method of transferring a thin layer from a source substrate having a surface layer of a first material along a free surface thereof to a target substrate having at least one surface layer of a second material along a free surface thereof, where the first material differs from the second material, includes forming within the surface layer of the source substrate a weakened zone delimiting a thin layer with respect to the free surface, and assembling the free surface of the source substrate to the free surface of the target substrate in a stack of alternating layers comprising the first and second materials, so that there are, on either side of an interface formed by bringing the free surfaces into intimate contact. The cumulative thicknesses of the layers of the first material are substantially equal to the cumulative thickness of the layers of the second material, the layers having thicknesses at least equal to 50 microns and at least 1000 times the depth at which the weakened zone is formed. The thin layer is detached by applying at least partially thermal energy to fracture the weakened zone.
US08252656B2 Zener triggered ESD protection
Electrostatic discharge (ESD) protection clamps (61, 95) for I/O terminals (22, 23) of integrated circuit (IC) cores (24) comprise a bipolar transistor (25) with an integrated Zener diode (30) coupled between the base (28) and collector (27) of the transistor (25). Prior art variations (311, 312, 313, 314) in clamp voltage in different parts of the same IC chip or wafer caused by prior art deep implant geometric mask shadowing are avoided by using shallow implants (781, 782) and forming the base (28, 68) coupled anode (301, 75) and collector (27, 70, 64) coupled cathode (302, 72) of the Zener (30) using opposed edges (713, 714) of a single relatively thin mask (71, 71″). The anode (301, 75) and cathode (302, 72) are self-aligned and the width (691) of the Zener space charge region (69) therebetween is defined by the opposed edges (713, 714) substantially independent of location and orientation of the ESD clamps (61, 95) on the die or wafer. Because the mask (71, 71″) is relatively thin and the anode (301, 75) and cathode (302, 72) implants (781, 782) relatively shallow, mask shadowing is negligible and prior art clamp voltage variations (311, 312, 313, 314) are avoided.
US08252654B2 Method for manufacturing memory cell
In a method for manufacturing a memory cell, a substrate is provided. A doped region with a first conductive type is formed in the substrate near a surface of the substrate. A portion of the substrate is removed to define a plurality of fin structures in the substrate. A plurality of isolation structures is formed among the fin structures. A surface of the isolation structures is lower than a surface of the fin structures. A gate structure is formed over the substrate and straddles the fin structure. The gate structure includes a gate straddling the fin structure and a charge storage structure located between the fin structure and the gate. A source/drain region is formed with a second conductive type in the fin structure exposed by the gate structure, and the first conductive type is different from the second conductive type.
US08252651B2 Method of manufacturing semiconductor device
A semiconductor device having a FIN type transistor including a FIN-shape semiconductor portion improved for reliability by suppressing scattering of the characteristics of the FIN-shape transistor by decreasing a difference between impurity concentration at an upper surface and impurity concentration on a lateral side of the FIN-shape semiconductor portion, in which a pad insulating film at a thickness of about 2 to 5 nm is formed to the upper surface of the FIN-shape semiconductor portion, cluster ions are implanted to one lateral side of the FIN-shape semiconductor portion from an oblique direction at a first implantation angle θ1 and then cluster ions are implanted to another lateral side of the FIN-shape semiconductor portion from an oblique direction at a second implantation angle θ2 in symmetrical with the first implantation angle θ1 and, subsequently, the cluster ions implanted to the FIN-shape semiconductor portion 10 are activated to form a diffusion region that forms a portion of a source region and a drain region.
US08252648B2 Power MOSFET device with self-aligned integrated Schottky and its manufacturing method
A power MOSFET device and manufacturing method thereof, includes the steps of selectively depositing a first conductive material in the middle region at the bottom of a contact trench and contacting with light-doped N-type epitaxial layer to form a Schottky junction and depositing a second conductive material at the side wall and bottom corner of the contact trench and contacting with P-type heavy-doped body region to form an ohmic junction. The first and second conductive materials can respectively optimize the performance of the ohmic contact and the Schottky contact without compromise. Meanwhile, the corner of the contact trench is surrounded by P-type heavy-doped region thereby effectively reducing the leakage currents accumulated at the corner of the contact trench.
US08252647B2 Fabrication of trench DMOS device having thick bottom shielding oxide
Semiconductor device fabrication method and devices are disclosed. A device may be fabricated by forming in a semiconductor layer; filling the trench with an insulating material; removing selected portions of the insulating material leaving a portion of the insulating material in a bottom portion of the trench; forming one or more spacers on one or more sidewalls of a remaining portion of the trench; anisotropically etching the insulating material in the bottom portion of the trench using the spacers as a mask to form a trench in the insulator; removing the spacers; and filling the trench in the insulator with a conductive material. Alternatively, an oxide-nitride-oxide (ONO) structure may be formed on a sidewall and at a bottom of the trench and one or more conductive structures may be formed in a portion of the trench not occupied by the ONO structure.
US08252643B2 Semiconductor device and manufacturing method thereof
A semiconductor device which is formed in a self-aligned manner without causing a problem of misalignment in forming a control gate electrode and in which a leak between the control gate electrode and a floating gate electrode is not generated, and a manufacturing method of the semiconductor device are provided. A semiconductor device includes a semiconductor film, a first gate insulating film over the semiconductor film, a floating gate electrode over the first gate insulating film, a second gate insulating film which covers the floating gate electrode, and a control gate electrode over the second gate insulating film. The control gate electrode is formed so as to cover the floating gate electrode with the second gate insulating film interposed therebetween, the control gate electrode is provided with a sidewall, and the sidewall is formed on a stepped portion of the control gate electrode, generated due to the floating gate electrode.
US08252641B2 Memory embedded logic semiconductor device having memory region and logic circuit region
In a method of manufacturing a semiconductor device, first contact holes reaching diffusion regions of a cell transistor, bit line contact holes reaching diffusion regions of the cell transistor, and interconnect grooves communicating with the bit line contact holes are buried in a first insulating film. In addition, first contact plugs and bit line contacts are respectively formed by burying conductive materials in the first contact holes, the bit line contact holes and the interconnect grooves, and the first contact plugs are electrically connected to a capacitor formed in a third insulating film through an opening formed in a second insulating film.
US08252637B2 Semiconductor device and method of fabricating the same
The purpose of the present invention is to provide a reliable semiconductor device comprising TFTs having a large area integrated circuit with low wiring resistance. One of the features of the present invention is that an LDD region including a region which overlaps with a gate electrode and a region which does not overlap with the gate electrode is provided in one TFT. Another feature of the present invention is that gate electrode comprises a first conductive layer and a second conductive layer and portion of the gate wiring has a clad structure comprising the first conductive layer and the second conductive layer with a low resistance layer interposed therebetween.
US08252635B2 Electronic system modules and method of fabrication
A trace routing method for a multi-layer interconnection circuit includes the steps of providing stacked contacts with trace stubs at input/output pads of said interconnection circuit, and limiting contacts between conductive layers to two-level contacts in routing areas where maximum routing density is desired.
US08252629B2 Method for making a stackable package
The present invention relates to a method for making a stackable package. The method includes the following steps: (a) providing a first carrier; (b) disposing at least one chip on the first carrier; (c) forming a molding compound so as to encapsulate the chip; (d) removing the first carrier; (e) forming a first redistribution layer and at least one first bump; (f) providing a second carrier; (g) disposing on the second carrier; (h) removing part of the chip and part of the molding compound; (i) forming a second redistribution layer; and (j) removing the second carrier. Therefore, the second redistribution layer enables the stackable package to have more flexibility to be utilized.
US08252625B2 Organic thin film transistor substrate and method of manufacturing the same
The present invention provides an organic thin film transistor substrate and a method of manufacturing the same capable of uniformly forming the thickness of a gate insulating layer and a protective layer and preventing overflow of an organic semiconductive layer.The organic thin film transistor according to the present invention comprises a gate line formed on a substrate; a data line which intersects the gate line with an organic gate insulating layer interposed therebetween to define a pixel area; a thin film transistor connected with the gate line and the data line and which includes an organic semiconductive layer; a pixel electrode connected with the thin film transistor and formed in the pixel area; an organic protective layer formed parallel with the gate line to cover the organic semiconductive layer and its peripheral area; a first border insulating layer stepwise formed so that the organic gate insulating layer and the protective layer are filled, and a second border insulating layer formed on the source electrode and the drain electrode of the thin film transistor so that the organic semiconductive layer is filled.
US08252621B2 Method for forming copper indium gallium chalcogenide layer with optimized gallium content at its surface
A method of forming a Group IBIIIAVIA solar cell absorber, which includes a top surface region of less than or equal to 300 nm depth. The Ga/(Ga+In) molar ratio within the top surface region is in the range of 0.1-0.3. The Group IBIIIAVIA solar cell absorber is formed by reacting the layers of a multilayer material structure which includes a metallic film including at least Cu and In formed on a base, a separator layer including Se is formed on the metallic film, a metallic source layer substantially including Ga formed on the separator layer, and a cap layer substantially including Se formed on the source layer.
US08252619B2 Treatment of thin film layers photovoltaic module manufacture
Systems and processes for treatment of a cadmium telluride thin film photovoltaic device are generally provided. The systems can include a treatment system and a conveyor system. The treatment system includes a preheating section, a treatment chamber, and an anneal oven that are integrally interconnected within the treatment system. The conveyor system is operably disposed within the treatment system and configured for transporting substrates in a serial arrangement into and through the preheat section, into and through the treatment chamber, and into and through the anneal oven at a controlled speed. The treatment chamber is configured for applying a material to a thin film on a surface of the substrate and the anneal oven is configured to heat the substrate to an annealing temperature as the substrates are continuously conveyed by the conveyor system through the treatment chamber.
US08252618B2 Methods of manufacturing cadmium telluride thin film photovoltaic devices
Methods for manufacturing a cadmium telluride based thin film photovoltaic device are generally disclosed. A resistive transparent layer can be sputtered on a transparent conductive oxide layer from a metal alloy target in a sputtering atmosphere of argon and oxygen that includes argon from about 5% to about 40%. A cadmium sulfide layer can then be formed on the resistive transparent layer. A cadmium telluride layer can be formed on the cadmium sulfide layer; and a back contact layer can be formed on the cadmium telluride layer. The sputtering can be accomplished within a sputtering chamber.
US08252617B2 Continuous large area imaging and display arrays using readout arrays fabricated in silicon-on-glass substrates
A vertically-integrated image sensor is proposed with the performance characteristics of single crystal silicon but with the area coverage and cost of arrays fabricated on glass. The image sensor can include a backplane array having readout elements implemented in silicon-on-glass, a frontplane array of photosensitive elements vertically integrated above the backplane, and an interconnect layer disposed between the backplane array and the image sensing array. Since large area silicon-on-glass backplanes are formed by tiling thin single-crystal silicon layers cleaved from a thick silicon wafer side-by-side on large area glass gaps between the tiled silicon backplane would normally result in gaps in the image captured by the array. Therefore, embodiments further propose that the pixel pitch in both horizontal and vertical directions of the frontplane be larger than the pixel pitch of the backplane, with the pixel pitch difference being sufficient that the frontplane bridges the gap between backplane tiles.
US08252616B2 Package structure of photodiode and forming method thereof
A package structure of photodiode and a forming method of the same are provided. The method includes providing a heat-dissipation plate; placing a circuit board on the heat-dissipation plate, the circuit board having an opening exposing a top surface of the heat-dissipation plate and a first contact pad located on a peripheral area of the opening; placing a carrier with a metal cladding surface into the opening, the carrier connecting the top surface of the heat-dissipation plate; placing a photodiode chip on the carrier wherein the bottom area of the photodiode chip is less than the metal cladding surface such that a portion of the metal cladding surface is exposed; and electrically connecting the exposed metal cladding surface to the first contact pad.
US08252615B2 Integrated circuit package system employing mold flash prevention technology
An integrated circuit package system that includes: providing a support structure including an integrated circuit and an electrical contact adjacent thereto; providing a first mold having a first cavity with a projection and a recess for collecting flash; engaging the first mold on the support structure with the first cavity over at least a portion of the integrated circuit and the projection and the recess between the at least a portion of the integrated circuit and the electrical contact; and injecting encapsulation material into the first cavity.
US08252612B2 Organic EL display device and manufacturing method thereof
An object of the invention is to provide an organic EL display device manufacturing method that allows the reliability of the organic EL display device having undergone a defect repair process to be improved. A method for manufacturing an organic EL display device, the method including an organic EL element substrate formation step of forming at least one organic EL element on an organic EL element substrate, the organic EL element including an organic EL film, an anode electrode and a reflection electrode that form a first conductive film provided below the organic EL film, and a cathode electrode that forms a second conductive film provided above the organic EL film, a resin sealing step of providing a thermoplastic sealing resin to cover the upper side of the organic EL element, a defect detection step of detecting a defect in the organic EL element, and a defect elimination step of eliminating the defect detected in the defect detection step by irradiating the defect with a laser beam.
US08252610B2 Method of manufacturing light emitting diode
A method for making a light emitting diode is provided, which includes first providing a light emitting diode chip. The light emitting diode chip includes a substrate and a p-type semiconductor layer, an active layer and an n-type semiconductor layer sequentially formed on the substrate. And then sections with different resistance are formed in the n-type semiconductor layer by implanting ions into the n-type semiconductor layer in an ion implanter. Finally, an electrode pad is deposited on the n-type semiconductor layer. The electrical resistances of the sections increase following an increase of a distance from the electrode pad to the sections.
US08252609B2 Curvature reduction for semiconductor wafers
A method for reducing curvature of a wafer having a semiconductor surface. One or more process steps are identified at which wafers exhibit the largest curvature, and/or wafer curvature that may reduce die yield. A crystal damaging process converts at least a portion of the semiconductor surface into at least one amorphous surface region After or contemporaneously with the crystal damaging, the amorphous surface region is recrystallized by recrystallization annealing that anneals the wafer for a time ≦5 seconds at a temperature sufficient for recrystallization of the amorphous surface region. A subsequent photolithography step is facilitated due to the reduction in average wafer curvature provided by the recrystallization.
US08252608B1 Measurement of a sample using multiple models
A sample with at least a first structure and a second structure is measured and a first model and a second model of the sample are generated. The first model models the first structure as an independent variable and models the second structure. The second model of the sample models the second structure as an independent variable. The measurement, the first model and the second model together to determine at least one desired parameter of the sample. For example, the first structure may be on a first layer and the second structure may be on a second layer that is under the first layer, and the processing of the sample may at least partially remove the first layer, wherein the second model models the first layer as having a thickness of zero.
US08252605B2 Method and composition for stabilizing liquid reagents
The invention relates to methods and compositions for removing a dissociated species from a fluid medium solution during and after it has detached from a solid-phase immersed in said medium, thereby allowing the concentration of free species to remain close to zero, and for improving the signal to noise ratio in assays. This is achieved by employing a substrate, such as a scavenging solid-phase, having an attached binding partner or partners (“scavenger”) for the specifically binding species and which is present during storage. This substrate may also contain regions for binding signal generating components attached to the solid-phase. This substrate binds any free species bleeding off the solid phase, increasing the reliability and sensitivity of assays. A subset of the substrates in the invention additionally forms cross-linked networks of solid-phase particles that further increase the sensitivity of assays.
US08252602B2 System for explosives detection
The system and method for explosives detection may be used for detecting the presence of explosive elements. A testing device may have a case with a cover. A sample holder may be disposed in the case for receipt of a sample element and may have a sample retainer. The sample element may have a swipe pad attached to a backing element a heater may be disposed in the sample holder wherein the heater may be below the swipe pad adjacent the backing element when the sample element may be positioned in the sample holder. The heater may be in communication with an electric power source. The case may have a plurality of cavities formed therein for receipt of a plurality of fluid containers. The plurality of fluid containers may have at least a first reagent fluid and a second reagent fluid.
US08252595B2 Metal abstraction peptide (MAP) tag and associated methods
Compositions comprising a tripeptide having the sequence XC1C2; wherein X is any amino acid such that XC1C2 is capable of binding a metal in a square planar orientation or square pyramidal orientation or both; and wherein C1 and C2 are the same or different; and wherein C1 and C2 individually are chosen from a cysteine and a cysteine-like nonnatural amino acid, as well as metal-XC1C2 complexes and methods for forming such complexes.
US08252594B2 Chemical markers
A composition containing a petroleum hydrocarbon, a biodiesel fuel or an ethanol fuel, and an organic marker compound.
US08252585B2 Neural progenitor cell populations
This invention provides populations of neural progenitor cells, differentiated neurons, glial cells, and astrocytes. The populations are obtained by culturing stem cell populations (such as embryonic stem cells) in a cocktail of growth conditions that initiates differentiation, and establishes the neural progenitor population. The progenitors can be further differentiated in culture into a variety of different neural phenotypes, including dopaminergic neurons. The differentiated cell populations or the neural progenitors can be generated in large quantities for use in drug screening and the treatment of neurological disorders.
US08252581B2 Apparatus for high throughput chemical reactions
Apparatus, systems, chips, and methods of performing a large number of simultaneous chemical reactions are provided herein. The chips of the invention comprise addressable units that can be addressed according to the temperature of the reaction to be run. The subject apparatus, systems, and chips are particularly suited for performing polymerase chain reactions on thousands of nucleic acid sequences, up to and including sequences of an entire genome of an organism of interest.
US08252578B2 Juvenile hemochromatosis gene (HFE2A) cleavage products and uses thereof
Isolated fragments of the HFE2A protein able to bind and modulate HFE2A and other proteins, such as hepcidin, involved in the iron metabolism pathway are disclosed, such fragments being of molecular weight of approximately 7 kDa to 43 kDa. Also disclosed are corresponding isolated polynucleotides encoding the fragments of the HFE2A protein. The invention includes derivatives and analogs of the polypeptide fragments of HFE2A, along with compositions of these, that are functionally active, i.e. capable of interacting with the HFE2A, as well as methods of production of the HFE2A cleavage products, derivatives and analogs, e.g. by recombinant means. Methods for identifying modulators of HFE2A, comprising contacting a test compound with HFE2A and determining a change in HFE2A activity due to the compound, are provided. Also taught are methods of diagnosing an animal afflicted with or at risk of developing a disease of iron metabolism comprising determining a change in the level, amount or activity of a fragment of an HFE2A obtained in a sample from said animal relative to the level, amount or activity of a fragment of an HFE2A obtained in a control sample from an unaffected animal, wherein a change identifies said individual as being affect by or at risk of developing a disease of iron metabolism. Methods for treating and/or preventing a disorder in animals comprising administering to an animal afflicted therewith, or at risk of developing said disorder, a therapeutically effective amount of an HFE2A modulator are provided.
US08252576B2 Use of prokaryote viruses to remediate bio-fouling
This invention provides a process for control in oil and gas wells and related facilities of prokaryote caused souring, fouling and corrosion by reduction of problematic prokaryotes with naturally occurring lysing organisms, particularly sulfate-reducing prokaryotes by proliferating suitable virulent lysing organisms under conditions in which problematic prokaryotes thrive, including in a gas production wellbore. The process provides in situ proliferation of virulent lysing organism in a wellbore by providing both virulent lysing organisms and their host prokaryotes to selectively grow an effective control amount and concentrations of lysing organisms in a well formation.
US08252573B2 Alpha-amylase variant with altered properties
The present invention relates to variants (mutants) of parent Termamyl-like alpha-amylases, which variant has alpha-amylase activity and exhibits altered properties relative to the parent alpha-amylase.
US08252571B2 Preparation of solvent-borne polymeric bioactive coatings
Processes for preparation of a protein-polymer composite material are provided according to embodiments of the present invention which include providing an admixture of a polymer resin, a surfactant and a non-aqueous organic solvent. An aqueous solution containing bioactive proteins and substantially free of surfactant is mixed with the admixture. The emulsion is mixed with a crosslinker to produce a curable composition. The curable composition is cured, thereby producing the protein-polymer composite material.
US08252570B2 Bone delivery device
Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to subjects.
US08252569B2 Microfluidic device and method for concentration and lysis of cells or viruses
A microfluidic device for the concentration and lysis of cells or viruses and a method of concentrating and lysing cells or viruses using the microfluidic device include: magnetic beads, a reaction chamber in which the magnetic beads are accommodated and a laser source. The reaction chamber includes a plurality of electrodes which cross each other and are separated by a dielectric to generate an electric field and a vibrating part agitating the magnetic beads in the chamber. The laser source radiates a laser onto the magnetic beads in the reaction chamber.
US08252566B2 Ethanol production from citrus waste through limonene reduction
The present invention relates to processes for producing ethanol from citrus waste wherein the level of fermentation-inhibiting compounds found in citrus waste or the complex polysaccharide or sugars derived therefrom is reduced using a pre-fermentation treatment step to lower the level of fermentation-inhibiting compounds to the fermentation feedstock.
US08252565B2 Method for production of microbial fermentation product
The present invention relates to a method for production of a diol form represented by the formula (2), which includes filtering a culture fluid obtained by microbial conversion using a compound represented by the following formula (1a) and/or formula (1b) as a substrate, using a filter having an aperture size of 10 to 100 μm; washing the residue on the filter with water or a solvent having an SP value outside the range of 8.3 to 20 (cal/cm3)1/2; subsequently dissolving the obtained cake in a solvent having an SP value of 8.3 to 20 (cal/cm3)1/2; and then filtering or centrifuging the solution.According to the present invention, 1-(2-hydroxyethyl)-2,5,5,8a-tetramethyldecahydronaphthalen-2-ol, which is useful as an intermediate for the production of 3a,6,6,9a-tetramethyldodecahydronaphtho[2,1-b]furan, can be efficiently produced at high purity.
US08252560B2 Process for producing useful substance with immobilized enzyme
The present invention relates to a process for producing a fatty acid, which includes feeding a liquid mixture formed of two liquid phases that flow in a co-current manner into a fixed bed-type reaction column packed with immobilized lipase, and performing a hydrolysis reaction when the two liquid phases are in contact with the immobilized lipase in the fixed-bed reaction column; wherein the fixed-bed reaction column comprises partition plates so as to comprise a plurality of tube- shaped structures, wherein each tube-shaped structure has a cross -section which is rectangular, circular, oval, or polygonal in shape with at least a part being unclosed and the cross-section has a representative length of 100 mm or less.
US08252558B2 Methods for amplifying and detecting nucleic acid sequences
The present invention, in different aspects and embodiments, provides nucleic acid amplification and detection methods that are both sensitive and fast. In various aspects there are disclosed amplification methods employing different combinations of primers to which can achieve exponential amplification and strand displacement, such as to generate a more than two fold increase of the amount of a target nucleic acid sequence during repeated cycles, while additionally permitting the production of single stranded products. Also provided are detection systems and kits.
US08252557B2 Peptide-containing culture medium for culturing animal cell
Disclosed is a culture medium for culturing an animal cell, which is characterized by containing a peptide comprising, as a constituent unit, an amino acid residue selected from the amino acid group consisting of serine, tyrosine and cysteine. The culture medium is suitable for the high level production of a protein by an animal cell.
US08252554B2 Halohydrin dehalogenases and related polynucleotides
The present invention relates to novel halohydrin dehalogenase polypeptides and the polynucleotides that encode them. These polypeptides are useful in the production of 4-substituted-3-butyric acid derivatives and vicinal cyano, hydroxyl substituted carboxylic acid esters. The invention also provides related vectors, host cells and methods.
US08252553B2 Specific binding sites in collagen for integrins and use thereof
The present invention identified a high affinity binding sequence in collagen type III for the collagen-binding integrin I domains. Provided herein are the methods used to characterize the sequence, the peptides comprising this novel sequence and the use of the peptides in enabling cell adhesion. Also provided herein are methods to identify specific integrin inhibitors, sequences of these inhibitors and their use in inhibiting pathophysiological conditions that may arise due to integrin-collagen interaction.
US08252549B2 Multi-purpose substrates useful for cell culture and methods for making
Described herein are multi-purpose substrates composed of (1) a base coated with a calcium phosphate coating and (2) a fluorophore-labeled collagen adsorbed on the calcium phosphate coating. The multi-purpose substrates are useful in culturing and studying the activity of a variety of cells. The multi-purpose substrates described herein can be used for both solution- and image-based analysis of cultured cells. New methods for producing and using such coated substrates are also disclosed.
US08252545B2 Peptides of a melanoma antigen and their use in diagnostic, prophylactic, and therapeutic methods
Immunogenic peptides of a melanoma antigen recognized by T cells, designated gp100, bioassays using the peptides to diagnose, assess or prognose a mammal afflicted with cancer, more specifically melanoma or metastatic melanoma, and use of the proteins and peptides as immunogens to inhibit, prevent or treat melanoma.
US08252542B2 Serpin B 13 as a marker for squamous cell carcinoma of the lung
Disclosed is a method aiding in the assessment of squamous cell carcinoma (SCC). It involves the use of the protein serpin B13 as a marker of SCC. Furthermore, the disclosure relates to a method for assessing lung cancer in a tissue sample derived from a patient having non-small cell lung carcinoma (NSCLC) and for differentiating SCC from adenocarcinoma or large cell carcinoma of the lung.
US08252540B2 Drug delivery system toward demyelinating lesion and biochemical marker of demyelinating lesion
It is intended to provide a drug delivery system toward a demyelinating lesion. It is also intended to provide a biochemical marker of a demyelinating lesion. A delivery system for a prophylactic and/or therapeutic agent for a demyelinating disease characterized in that a substance capable of specifically recognizing Contactin is conjugated to an active ingredient of a prophylactic and/or therapeutic agent for a demyelinating disease is provided. Also provided is a method of evaluating and/or differentiating a demyelinating disease, including measuring the expression of Contactin in a body fluid.
US08252538B2 MicroRNA expression signature for predicting survival and metastases in hepatocellular carcinoma
Provided herein are methods and compositions for the diagnosis, prognosis and treatment of Hepatocellular carcinoma (HCC). Also provided are methods of identifying anti-HCC agents.
US08252537B2 Identification of a DNA variant associated with adult type hypolactasia
The present invention relates to a nucleic acid molecule comprising a 5′ portion of an intestinal lactase-phlorizine hydrolase (LPH) gene contributing to or indicative of the adult-type hypolactasia. The present invention further relates to methods for testing for the presence of or predisposition to adult-type hypolactasia that are based on the analysis of an SNP contained in the above recited nucleic acid molecule. Additionally, the present invention relates to diagnostic composition and kit useful in the detection of the presence of or predisposition to adult-type hypolactasia.
US08252536B2 Integrated nucleic acid analysis
The present invention relates to an integrated method of nucleic acid analysis, and more particularly to a simplified sample pre-treatment, which renders the method more easily automated, where the sample is provided on or applied onto a solid matrix and the subsequent amplification and detection steps are performed in one single, sealed reaction vial without removing the matrix.
US08252535B2 RNA interference tags
The invention relates to a method for inhibiting the expression of a target gene in a eukaryotic cell. The method includes the following steps: a) providing at least one eukaryotic cell, the cell being capable of RNA interference, b) transfecting the eukaryotic cell with a composition that includes a genetic construct that includes an siRNA tag, and a target gene that forms a transcription unit together with the siRNA tag, and c) introducing at least one siRNA that is complementary to the siRNA tag of the transfected genetic construct to inhibit the expression of the target gene.
US08252532B2 Regulators of the non-genomic action of progesterone and methods of use
A progesterone regulator capable of modulating the non-genomic action of progesterone and methods of using the progesterone regulator are described. The progesterone regulator is useful for attenuating progesterone's inhibition of apoptosis and for the treatment of patients having a progesterone-responsive tissue disease such as endometriosis or cancer, particularly ovarian cancer, as well as for diagnosis, prognosis, and/or staging of ovarian cancers.
US08252524B2 Method of screening pharmaceutical compositions that promote nuclear transfer of Cdc42 protein
A nuclear transfer promoter for Cdc42 protein comprising an isoprenoid synthesis inhibitor and/or a geranylgeranyl transferase inhibitor such as an HMG-CoA synthase inhibitor, an HMG-CoA reductase inhibitor, an AMPK activator or a farnesyl pyrophosphoric acid synthase preparation; utilization thereof; a method therefor; a blood vessel remedy comprising the nuclear transfer promoter for Cdc42 protein as the active ingredient; and a method of screening a blood vessel remedy which comprises assaying the ability of Cdc42 protein to transfer into nucleus.
US08252522B2 Species detection methods and systems
The disclosure provides methods, systems and kits for cellular and subcellular identification in a rapid, throughput manner.
US08252520B2 Methods and compounds for inhibiting Hec1 activity for the treatment of proliferative diseases
The present invention provides methods and compounds for inhibiting HEC1 activity for the treatment of diseases involving cell hyperproliferation, e.g. cancer. The present invention also provides methods of identifying compounds for inhibiting HEC1 activity.
US08252518B2 Chemically amplified positive resist composition and resist patterning process
There is disclosed a chemically amplified positive resist composition to form a chemically amplified resist film to be used in a lithography, wherein the chemically amplified positive resist composition comprises at least, (A) a base resin, insoluble or poorly soluble in an alkaline solution, having a repeating unit whose phenolic ydroxyl group is protected by a tertiary alkyl group, while soluble in an alkaline solution when the tertiary alkyl group is removed; (B) an acid generator; (C) a basic component; and (D) an organic solvent, and a solid component concentration is controlled so that the chemically amplified resist film having the film thickness of 10 to 100 nm is obtained by a spin coating method. There can be provided, in a lithography, a chemically amplified positive resist composition giving a high resolution with a suppressed LER deterioration caused by film-thinning at the time of forming a chemically amplified resist film with the film thickness of 10 to 100 nm, and a resist patterning process using the same.
US08252508B2 Positive photosensitive composition and method of forming resist pattern
A positive photosensitive composition comprises: (A) 5 to 20 parts by weight of the total amount of at least one compound that generates an acid upon irradiation with an actinic ray; and (B) 100 parts by weight of the total amount of at least one fluorine atom-containing resin having a group that increases a solubility of the resin in an alkaline developer by the action of an acid.
US08252504B2 Polymer, resist composition, and patterning process
A polymer obtained through copolymerization of a monomer having a hexafluoroalcohol pendant whose hydroxyl moiety has been protected and a monomer having an acid labile group is useful as an additive to a photoresist composition for immersion lithography. When processed by immersion lithography, the resist composition exhibits good water repellency and water slip and produces few development defects.
US08252502B2 Method for producing toner and resulting toner
A method for producing a toner is provided that comprises a kneading step, a milling step, a pre-externally adding step, in which at least a part of an external additive is externally added to the powder to prepare a mixture, a classifying step, a recycle step, and a post-externally adding step, wherein the internally added amount X of the external additive in the toner is regulated within a range of 0.2 part by mass to 3.0 parts by mass based on 100 parts by mass of the toner base.
US08252498B2 Toner for printing method and method for electrophoretic printing process
Amphiphilic toner which has both hydrophilic groups and lipophilic groups in the molecule, use thereof for an electrophoretic printing process, and method for an electrophoretic printing process using it. The toner is first dispersed in a non-polar carrier liquid, the toner-containing carrier liquid being transported from a charge image carrier by means of a transfer roller to a point of transfer and from there transferred to a substrate. A polar liquid is added before transfer of the toner to the substrate.
US08252496B2 Developing agent and method for producing the same
A method for producing a developing agent including preparing a dispersion liquid containing first fine particles containing a binder resin and second fine particles containing a color developable compound, a color coupler, and a color eraser, and aggregating the first and second fine particles in the dispersion liquid to form aggregated particles.
US08252495B2 Electrophotographic toner and manufacturing method thereof
The electrophotographic toner of the present invention comprises toner particles and inorganic fine powder externally added to the toner particles. The toner particles comprise a core particle containing at least a resin, a coloring agent and wax, a first shell layer that is formed on the surface of the core particle to prevent inorganic fine powder from being buried, and a second shell layer that is formed on the surface of the first shell layer to retain inorganic fine powder. This makes it possible to inhibit inorganic fine powder that is an external additive from being buried in a toner and prevent deterioration of developing performance, reduction in transfer efficiency, blocking of a developer and toner aggregation.
US08252492B2 Toner for electrostatic development, image forming apparatus, and image forming method
An embodiment of toner for electrostatic development may include toner base particles, and resin fine particles. Further, some embodiments may include external additives, such as hydrophobic silica. In some embodiments, the resin fine particles may include a polymer having an isobornyl group-containing acrylate monomer.
US08252491B2 Method of forming a marker, substrate having a marker and device manufacturing method
A marker, for example an alignment marker or an overlay marker is formed in two steps. First, a pattern of two chemically distinct feature types having a pitch comparable to product features is formed. This pattern is then masked by resist in the form of the desired marker, which has a larger pitch than the pattern. Finally, one of the two feature types is selectively etched in the open areas. The result is a marker with a large pitch suitable to be read with long wavelength radiation but the edges of the features are defined in an exposure step having a pitch comparable to the product features.
US08252490B2 Color filter and solid state imaging device having a colored pattern formed from a curable composition
A color filter or solid state imaging device comprising a colored pattern formed from a curable composition which includes (A) a pigment, (B) a compound having a defined cyclic urea structure and having an acid group or a basic group, (C) a dispersant, (D) a solvent, (E) a radical polymerizable compound, and (F) a photopolymerization initiator. The pigment may be a pigment having a urea structure or an imide structure. The pigment may also be a pigment having a barbituric skeleton.
US08252489B2 Mask-shift-aware RC extraction for double patterning design
A method includes providing a layout of an integrated circuit design, and generating a plurality of double patterning decompositions from the layout, with each of the plurality of double patterning decompositions including patterns separated to a first mask and a second mask of a double patterning mask set. A maximum shift between the first and the second masks is determined, wherein the maximum shift is a maximum expected mask shift in a manufacturing process for implementing the layout on a wafer. For each of the plurality of double patterning decompositions, a worst-case performance value is simulated using mask shifts within a range defined by the maximum shift. The step of simulating the worst-case performance includes calculating capacitance values corresponding to mask shifts, and the capacitance values are calculated using a high-order equation or a piecewise equation.
US08252484B2 Separator for fuel cell having electrically conducting flow path part
A high-performance separator for a fuel cell is provided that includes an electrically conducting flow path part and an integrated insulating outer circumferential part surrounding the flow path part. The flow path part includes an electrically conducting resin composition including a carbonaceous material (A) and a thermoplastic resin composition (B) at a mass ratio (A)/(B) of 1 to 20 with the total mass of (A) and (B) accounting for 80 to 100 mass % in the composition. The flow path part has a corrugated shape having a recess and a projection on each of front and back surfaces thereof, where the recess constitutes a groove for a flow path, and a thickness of 0.05 to 0.5 mm and a maximum thickness/minimum thickness ratio of 1 to 3. The insulating outer circumferential part includes an insulating thermoplastic resin composition having a volume resistivity of 1010 Ωcm or more.
US08252482B2 Solid polymer fuel cell
A fuel cell includes a power generation portion. The power generation portion at least has a fuel electrode, an oxygen electrode, a solid polymer electrolyte membrane interposed therebetween, and a first opening member including an opening on the fuel electrode side. The fuel cell includes a fuel storage portion storing fuel and including a second opening member that includes an opening. The fuel cell includes a container portion provided on the power generation portion containing the fuel storage portion. The container portion is designed to contain the fuel storage portion such that the fuel storage portion is attachable to and detachable from the power generation portion, while the opening of the first opening member and the opening of the second opening member are positioned so as to be communicable with each other.
US08252481B2 Fuel cell system and solid polymer electrolyte film
According to the invention, a fuel cell system features a fuel cell (14) having a solid polymer electrolyte membrane (4), and an antioxidant residing in or contacting the solid polymer electrolyte membrane (4), for inactivating active oxygen.
US08252479B2 Solid oxide fuel cell
The solid oxide fuel cell of the present invention has a substrate (1); an electrolyte (3) that is disposed on one surface of the substrate (1); and at least one electrode element E having an anode (5) and a cathode (7) disposed on the same surface of the electrolyte (3) with a predetermined space therebetween.
US08252477B2 Direct-flame fuel cell
A direct-flame fuel cell according to the invention has a cell in which a solid electrolyte 1 is sandwiched between an anode 2 and a cathode 3. The anode 2 contains one or more kinds of alkaline metal compounds or alkaline earth metal compounds which are effective in suppressing soot generation due to exposure to a flame. Where the anode 2 includes two or more layers 2a and 2b, the one or more kinds of alkaline metal compounds or alkaline earth metal compounds are contained in the outermost layer 2b.
US08252473B2 Fuel cell-equipped vehicle and control method for fuel cell-equipped vehicle
A vehicle equipped with a fuel cell recognizes an external characteristic of a following mobile unit. Corresponding to the recognized characteristic, the vehicle controls the permission, the amount and the prohibition of discharge of the water produced along with electricity generation of the fuel cell.
US08252470B2 Fuel cell system
A temperature sensor detects the temperature of a coolant circulating in a coolant supply system of a fuel cell. A control unit monitors the temperature detected by the temperature sensor. When the temperature of the coolant is higher than a target temperature, the control section switches a rotary valve to a radiator-side flow path so that a radiator cools the coolant, and when the temperature of the coolant is lower than the target temperature, the control section switches the rotary valve to a bypass-side flow path to raise the temperature of the coolant through FC generation so that the temperature detected by the temperature sensor is equal to the target temperature. During the process above, in a low temperature environment, the target temperature is raised to a temperature that is higher than a target temperature during a normal operation, while a heater heats the coolant. Through the above processing, the temperature inside the fuel cell can be prevented from decreasing excessively even in the low temperature environment.
US08252463B2 Modified current collector of lithium ion battery, method for making the same, and lithium ion battery using the same
A modified current collector includes a metal plate and a protective film disposed on a surface of the metal plate. A composition of the protective film is at least one of AlxMyPO4 and AlxMy(PO3)3. M represents at least one chemical element selected from the group consisting of Cr, Zn, Mg, Zr, Mo, V, Nb, and Ta. A valence of M is represented by k, wherein 0
US08252461B2 Lithium-sulfur battery and cathode therefore
An improved cathode suitable for lithium-sulfur batteries, a battery including the cathode, and a battery including a separator containing inorganic fillers are disclosed. The cathode includes sulfur and a metal oxide and optionally includes an additional polymeric material. The metal oxide reduces dissolution of sulfur at the cathode and reduces sulfur-containing deposits on the battery anode, thereby providing a battery with relatively high energy density and good partial discharge performance. The separator also reduces unwanted diffusion of sulfur species.
US08252458B2 Electrolyte-absoring, non-permeable sealing materials
An engineered thermoplastic sealing member for LiFeS2 and other nonaqueous cells is disclosed. The optimal material displays a propensity to absorb at least 10 weight percent of an ether-based electrolyte while, at the same time, displaying a vapor transmission rate of less than 500((g×mil)/(100 in2×days).
US08252457B2 Battery cell and power supply
A battery (2) includes an insulating member (40) fitted into a hole (26) in a case (20), and electrode terminals (60, 70), each being passed through the insulating member (40) and extended out of the case (20). The insulating member (40) includes: a first insulating portion (42) that isolates each of the electrode terminals (60, 70) from the inner surface of the hole (26) and closes the interface between each of the electrode terminals (60, 70) and the inner surface; and a second insulating portion (48) formed along the surface of each of the terminals (60, 70) at the outer end portion of the insulating member (40).
US08252455B2 Battery pack, vehicle equipped with the battery pack, and device equipped with the battery pack
A secondary battery includes a cylindrical battery case, a positive and negative electrode body group, a top plate and a battery lid connected to first and second electrode bodies of the electrode body group respectively. The secondary battery further includes a current collector placed on an end of the electrode body group on the top plate side and connected to the first electrode body of the electrode body group and a spacer placed between the top plate and the current collector. The top plate is partly formed with a thin portion. The spacer is formed with through holes in positions corresponding to the thin portion. The portion of the current collector corresponding to the thin portion is in contact with the thin portion through the through hole. The thin portion is deformed when the internal pressure of the battery case rises, thereby breaking electric connection between the top plate and the current collector.
US08252442B2 Battery cover latching assembly
A battery cover latching assembly, detachably securing a battery cover to a housing, includes a button, battery cover, elastic member arranged between the button and the housing, and a resisting member resisting the battery cover away from the housing. The button includes a locking portion. The battery cover includes a corresponding locking member. The locking portion is slidably received in the housing to clamp or release the locking member.
US08252441B2 Spacers for fixing battery cells within a battery package casing and associated systems and methods
A battery support system for supporting at least one battery cell disposed within a battery package is described herein. In one embodiment, the battery support system includes a spacer element having a frame member configured to be proximate to an end of the battery cell. The frame member has first projections extending away from the frame member in a first direction. The first projections are configured to engage a portion of the side surface of the battery cell. In a particular embodiment, the frame member further has second projections extending away from the frame member in a second direction generally opposite the first direction. The second projections are configured or positioned to provide a stand-off between the end of the battery cell and an interior surface of the battery package in which the battery support system is disposed.
US08252440B2 Sealed battery
The present invention provides a sealed battery 10 including an electrode body 14 formed by winding a positive electrode plate 11, a negative electrode plate 12 and a separator 13 interposed therebetween so as to have a hollow portion 14a at the center, a tube-shaped center pin 20a inserted in the hollow portion 14a, a battery outer can 17 containing the electrode body 14, an external terminal 19 also serving as a safety valve 18 evacuating gas when a gas pressure in the battery outer can 17 exceeds a predetermined value. A slit 24a is formed on a peripheral surface of the center pin 20a, and a cutout part 22a is formed on at least an end of the center pin 20a at the external terminal 19 side.
US08252435B2 Cutting tool, process for producing the same, and method of cutting
[PROBLEMS] To provide a cutting tool consisting of a hard material improved in the adherence between a substratum of cemented carbide having hard phases bound by a binder metal and a TiN layer superimposed on a surface of the substratum, and provide a process for producing the same. [MEANS FOR SOLVING PROBLEMS] There is provided a cutting tool consisting of a hard material, characterized in that the hard material has a substratum containing hard phases and a binder metal and a TiN layer superimposed on a surface of the substratum, and that the substratum has β-phases consisting of at least one solid solution of carbide, nitride or carbonitride containing W and at least one member selected from among Ti, Ta, Nb and Zr, and that at least some of the β-phases lie at a surface of the substratum, and that the TiN layer has crystals with the same orientation relationship as that of β-phase crystals just above the β-phases of the substratum surface.
US08252432B2 Composition for charge-transporting film and ion compound, charge-transporting film and organic electroluminescent device using same, and method for manufacturing organic electroluminescent device and method for producing charge-transporting film
A composition for preparing a charge-transport film is provided. The composition comprises, at least: a charge-transporting compound having an ionization potential of between 4.5 and 5.5 ev; and an ionic compound selected from the group consisting of the compounds of formulae (1)-(3), wherein R11, R21 and R31 are each independently an organic group bound to A1-A3, via a carbon atom; R12, R22, R23 and R32-R34 are each independently an arbitrary group. Two or more neighboring groups of R11-R34 may combine to form a ring. A1-A3 are each an element of the third and subsequent periods in the periodic table. A1 is an element of group 17 of the long form periodic table; A2 is an element of group 16 and A3 is an element of group 15. Z1n1−-Z3n3− are counter anions and n1-n3 are an ionic valency of the counter anion.
US08252430B2 Heat-resistant member
A heat-resistant member is provided that includes a Ni-base superalloy substrate coated with at least one substance. The substrate and the substance are formed of materials that are substantially in a state of thermodynamic equilibrium, or in a state similar to a state of thermodynamic equilibrium, so that interdiffusion is suppressed. The heat-resistant member therefore inhibits interdiffusion of elements at the substrate/coating interface even at elevated temperatures of 1,100° C. and higher.
US08252427B2 Bonding wood composites with resin solids-fortified phenol-formaldehyde resin
The invention comprises an aqueous phenol-formaldehyde resole resin liquid fortified with powdered (e.g., spray dried) phenol-formaldehyde resole resin, preparing wood composites, particularly oriented strand board (OSB), waferboard, particleboard, medium density fiber board, and hardboard, using the solids-fortified liquid resin, and related wood composites bonded with the solids-fortified resin.
US08252423B2 Laminate and use thereof
There is provided a resin laminate having a layer construction of a first inorganic material layer/insulating layer/second inorganic material layer or a layer construction of an inorganic material layer/insulating layer, wherein the insulating layer has a multi-layer structure of two or more resin layers of a core insulating layer and an adhesive insulating layer. In this case, the resin laminate has the adhesive insulating layer which can realize optimal etching, is suitable for etching by a wet process, and has excellent adhesion. At least one of the layers constituting the insulating layer is formed of a polyimide resin which comprises repeating units represented by formula (1) and has a glass transition point of 150 to 360° C. and is dissolvable in a basic solution at a rate of more than 3 μm/min, preferably more than 5 μm/min, and most preferably more than 8 μm/min.
US08252422B2 Hybrid silicon wafer and method of producing the same
Provided is a hybrid silicon wafer made of a wafer comprised primarily of two or more types of concentric single-crystal silicon or polycrystalline silicon prepared by mutually integrating one in a molten state and another in a solid state, and having specific resistances that differ by two orders of magnitude or more. Additionally provided is a method of manufacturing a hybrid silicon wafer, wherein high specific resistance silicon or an ingot comprised primarily of silicon is disposed at a central portion or a decentered position in a crucible, a nugget or powdered silicon having a specific resistance that is lower by two orders of magnitude or more than the ingot is filled in a void part around the ingot in the crucible, the nugget or powdered silicon is selectively melted and integrated with the ingot to form a complex, and a wafer shape is cut out therefrom. The provided hybrid silicon wafer comprises the functions of both a polycrystalline silicon wafer and a single-crystal wafer, or two or more polycrystalline silicon wafers having different functions.
US08252421B2 Gas barrier film
The present invention relates to a gas barrier film where a polyurethane type resin layer and an inorganic layer are disposed in this order from a polyester type resin film side on at least one surface of a polyester type resin film, wherein the polyurethane type resin constituting said polyurethane type resin layer is a resin containing a skeleton represented by the following formula (1) and/or the following formula (2).
US08252420B2 Polyamideimide polybenzimidazole containing intermediate transfer members
An intermediate transfer member that includes a mixture of a polyamideimide, a polybenzimidazole, and an optional conductive filler.
US08252418B2 Drug delivery system and method of manufacturing thereof
In one embodiment, a drug delivery system and method provide a member including a combination of a drug substance and a polymer or other material, and an encapsulating layer formed in an outer surface of the member by gas cluster ion beam irradiation of the outer surface of the member, which encapsulating layer is adapted to determine one or more characteristics of the drug delivery system.
US08252416B2 Nanocrystal-metal oxide complex comprising at least two different surfactants and method for preparing the same
Disclosed herein is a nanocrystal-metal oxide complex. The nanocrystal of the nanocrystal-metal oxide complex is substituted with two or more different types of surfactants which are miscible with a metal oxide precursor and enable maintenance of luminescent and electrical properties of the nanocrystal. The nanocrystal-metal oxide complex exhibits superior optical and chemical stability and secures high luminescent efficiency of the nanocrystal. Accordingly, when the nanocrystal-metal oxide complex is used as a luminescent material of an electroluminescent device, it can improve luminescent efficiency and reliability of products. Further disclosed herein is a method for preparing the nanocrystal-metal oxide complex.
US08252414B2 Polymer particles with additives encapsulated in microvoids
Porous particles comprising a polymer binder and at least one additive distinct from any pore stabilizing compound present in the particle, wherein: the polymer binder comprises a solid compositionally continuous phase having an external particle surface; discrete pores are dispersed within the solid compositionally continuous phase, forming internal pore surfaces; and the at least one additive is present primarily in the discrete pores. The additive may further preferably not be present in the solid compositionally continuous phase, and be substantially absent from the external particle surface. A toner set for forming a color electrophotographic image comprising a plurality of different colored toners, where at least one of the different colored toners comprise such porous particles comprising additives, and in a particular embodiment wherein at least two different colored toners each comprise different pigments present primarily in the internal pores. A process of making such porous particles.
US08252410B2 Ceramic cover wafers of aluminum nitride or beryllium oxide
Embodiments of the invention provide a method and apparatus for protecting a susceptor during a cleaning operation by loading a ceramic cover substrate containing either aluminum nitride or beryllium oxide onto the susceptor before introducing the cleaning agent into the chamber. In one embodiment, an aluminum nitride ceramic cover substrate is provided which includes an aluminum nitride ceramic wafer having a thermal conductivity of greater than 160 W/m-K, a circular-shaped geometry having a diameter within a range from about 11 inches to about 13 inches, a thickness within a range from about 0.030 inches to about 0.060 inches, and a flatness of about 0.010 inches or less. The thermal conductivity may be about 180 W/m-K, about 190 W/m-K, or greater. The thickness may be within a range from about 0.035 inches to about 0.050 inches, and the flatness may be about 0.008 inches, about 0.006 inches, or less.
US08252409B2 Durable printed composite materials and associated methods
A durable printed composite material can include a printable layer having an image reverse printed thereon. The printable layer can be a transparent or translucent material. A metallic layer can be adhered to the image side of the printable layer using an adhesive layer. The layers are formed such that at least a portion of the metallic layer is visible through the printable layer. A method of forming a durable printed composite material can include reverse printing an image on a printable layer to form a printed surface. A metallic layer can then be adhered to the printed surface of the printable layer. Heat and pressure can be applied to the metallic layer to produce a durable printed composite material. The metallic layer can be at least partially visible through the printable layer. The durable printed composite material provides a medium which has an image having a reflective metallic background useful in a variety of applications.
US08252406B2 Carrier foil
In order to produce a carrier foil for printed circuit boards, which is particularly suitable for high component densities, it is proposed that said carrier foil be produced from a polymer material comprising a thermoplastically processable, substantially fully fluorinated plastics material.
US08252402B2 Optically detectable adhesive tape with reduced gloss properties
An adhesive tape for flying splice of flat web material which has been wound to form rolls, the adhesive tape having at least one carrier layer and a layer of adhesive, at least part of that surface of the carrier layer that faces that layer of adhesive being optically detectable, or optically detectable means being provided between the carrier layer and the layer of adhesive, and the layer of adhesive being designed such that the optical detection can be made through the layer of adhesive. The adhesive tape is modified such that its gloss value, i.e. the ratio of directed fraction and diffusely reflected fraction of the light stream incident on the surface, on the external surface of the layer of adhesive is reduced by at least 20% relative to an unmodified adhesive tape of otherwise identical construction.
US08252392B2 Recording medium
The invention provides a recording medium comprising a substrate and an ink receiving layer that is provided on the substrate and contains alumina hydrate and a binder. A surface of the ink receiving layer is covered with a partial coating formed by a plurality of coatings containing a cationic polyurethane. The plurality of coatings have an average major diameter of 0.03 μm or more and less than 1.00 μm. The partial coating provides a coverage of 10% or more and less than 70% with respect to the surface of the ink receiving layer.
US08252391B2 Card
An article such as a greeting card (10) comprising a sheet (11) defining a first portion (16) and a second portion (18) connected together. The first portion (16) is adapted for erection into a three-dimensional form and the second portion (18) is adapted for location adjacent the three-dimensional form. The first and second portions (16, 18) are foldably connected together, whereby the second portion (18) can be folded into the location adjacent the three-dimensional form and secured at that location. The first portion (16) has two opposed edges (26, 28) adapted to be drawn together to create the three-dimensional form. The greeting card (10) can be delivered in a collapsed condition to an intended recipient in ways similar to conventional cards and can be readily assembled into a three-dimensional form to create interest and facilitate display.
US08252389B2 Mesogenic dimers
The invention relates to novel mesogenic dimeric compounds which are especially suitable for use in birefringent films with negative optical dispersion, to novel liquid crystal (LC) formulations and polymer films comprising them, and to the use of the dimers, formulations and films in optical, electrooptical, electronic, semiconducting or luminescent components or devices.
US08252386B2 Method for forming UV-patternable conductive polymer film
According to a method for forming a UV patternable conductive polymer film, vapor-phase polymerization (VPP) may be employed to synthesize a conductive polymer, and a UV-curable polymer resin may be used as a binder to form a conductive polymer film, the method including coating a mixed solution of a binder and an oxidant on a transparent substrate, synthesizing a conductive polymer by vapor-phase polymerization (VPP) on the coating to form a conductive polymer film and patterning the conductive polymer film with UV light. The conductive polymer film may be patterned in a relatively simple manner while maintaining increased conductivity, improved transparency and improved flexibility. Therefore, the conductive polymer film may be used as a material for transparent electrodes of a variety of display devices, e.g., LCD and PDP devices, and electronic devices, e.g., ELs and TFTs.
US08252385B2 Spin-printing of electronic and display components
Processes for printing conductors, insulators, dielectrics, phosphors, emitters, and other elements containing elongated functional particles aligned along the axis of a spun fiber or film that can be for electronics and display applications are provided. Also provided are viscoelastic compositions used in the processes, and devices made therefrom.
US08252384B2 Method for feeding particles of a coating material into a thermal spraying process
In a method particles in a thermal spraying process are entrained by a carrier gas stream and deposited on a component to be coated. The particles are dispersed in a liquid or solid additive before being introduced into a supply line which issues into the thermal spraying apparatus, the additive, after leaving the supply line, being transferred into the gaseous state in the carrier gas stream. A liquid additive evaporates or a solid additive is sublimated, whereby the particles in the carrier gas stream are separated. The dispersal of the particles in the additive simplifies an exact metering and prevents the particles from forming lumps, so that improved layers can be deposited by virtue of an improved homogeneity of the carrier gas stream. As the additive has been transferred into the gaseous state, it is not deposited in the layer.
US08252383B2 Method and apparatus for ejecting liquefied material
A method for ejecting liquid crystal from a droplet ejection head onto a mother glass substrate is disclosed. The ejecting method includes: substantially equalizing the temperature in the proximity of the droplet ejection head when the droplet ejection head is held in a standby state at a standby position with the temperature in the proximity of the droplet ejection head at the time when the droplet ejection head ejects the liquid crystal onto the mother glass substrate; and moving the droplet ejection head from the standby position to a position at which the mother glass substrate is located, thereby performing ejection of the liquid crystal onto the mother glass substrate.
US08252382B2 Aluminum wheel having high gloss
The present invention relates to an aluminum wheel having high gloss and a method for manufacturing the same, and the method for manufacturing an aluminum wheel having high gloss includes the steps of: (i) coating a primary coating powder paints for increasing a flatness of an aluminum wheel having a rough surface and improving an adhesive force to a silver mirror coating surface, (ii) forming of silver coating layer forming a mirror surface having a high gloss and high reflectivity on the powder paints coated surface using a silver coating solution, and (iii) forming at least one transparent top coating for protecting the silver mirror surface and increasing an abrasion resistance and a saltwater resistance after the step (ii). In accordance with the present in an aluminum wheel having high gloss and high reflectivity can be manufactured in a simple processes and relative inexpensive cost.
US08252381B1 Molecular coating on metal surfaces
A coated metal surface is disclosed, with a chemically-bonded film of long-chain organic groups. Such coating may be hydrophobic, and therefore repel the presence of water. This allows the surface to resist corrosion and surface oxidation, without diminishing the desired metallic characteristics of the surface. Further disclosed are methods for applying and coating on various substrates. Such coating may be advantageously applied to protect metals from corrosive environments such as air, water, chemicals, and bodily fluids.
US08252376B2 Method for restoring the microstructure of a textured article and for refurbishing a gas turbine blade or vane
During a solution heat treatment grain recrystallization may occur of a textured article, especially at the surface rim.The present invention provides a method for restoring the microstructure of a textured article, which comprises coating the surface of the article with a high temperature stable surface coating or by a controlled development of an oxide scale and subsequently performing a solution heat treatment, thereby maintaining said thermally stable surface coating.
US08252367B2 Methods and apparatus to fabricate soft magnetic film with preferred uniaxial anisotropy for perpendicular recording
Soft magnetic film fabricated with preferred uniaxial anisotropy for perpendicular recording. One type of cathode design has a field direction that is parallel to the direction of the Hex of the second SUL with a magnetically-pinned first SUL. In addition, SUL structures having low AP exchange energy also are disclosed. The SUL structure combines the cathode field direction of the SUL2 with the pinned SUL1. The SUL1 is magnetically pinned to the pinning layer and the pinning direction is parallel to the direction of the cathode field applied during deposition of the SUL1. High Hc ferro-magnetic materials may be deposited onto a heated substrate that is magnetized along the radial direction by the cathode field. The pinning field may be higher than the cathode field, indicating that the cathode field during deposition of the SUL2 cannot disturb the magnetic state of the SUL1 pinned to pinning layer.
US08252366B2 Method for making toughened electrode-supported ceramic fuel cells
A solid oxide electrochemical device having a laminar composite electrode with improved electrochemical and mechanical performance, the laminar composite electrode comprising a porous support electrode layer, a thin and patterned structure layer, and a thin and dense electrolyte layer and methods for making.
US08252364B2 Metal pattern forming method, metal pattern obtained by the same, printed wiring board, conductive film forming method, and conductive film obtained by the same
The present invention provides a method of forming a metal pattern and a metal pattern obtained by the method. The method includes the steps of (I) forming on a substrate a polymer layer in which a polymer having a functional group that interacts with an electroless plating catalyst or a precursor thereof is chemically bonded directly to the substrate in a pattern form, (II) adding the electroless plating catalyst or precursor thereof to the polymer layer, and (III) forming a metal layer in the pattern form by electroless plating. The present invention also provides a method of forming a conductive film, including the steps of (A) forming on a substrate a polymerization initiating layer in which a polymer having, on a side chain thereof, a crosslinking group and a functional group having polymerization initiating capability is immobilized by a crosslinking reaction on the surface of the base material, (B) generating a graft polymer by chemically bonding a polymer having a functional group that interacts with an electroless plating catalyst or a precursor thereof directly onto the entire surface of the polymerization initiating layer, (C) adding the electroless plating catalyst or precursor thereof to the graft polymer, and (D) forming a metal layer by electroless plating.
US08252363B2 Method of thinning a block transferred to a substrate
The invention relates to a method of thinning a block transferred to a substrate. According to the invention, the method includes depositing a stop layer at least onto the substrate and in a way adjacent to and contiguous with the transferred block. The stop layer is made out of material of greater resistance or hardness than the material of the transferred block and of smaller thickness than that of the transferred block. The method further includes actuating the thinning of the transferred block. The thinning time is pre-programmed as a function of a predetermined speed of thinning the transferred block, the thinning time being selected so that the thinning also attacks the stop layer.
US08252359B2 Method for the preparation of refreshing drink and use thereof
The present invention discloses a nutritious, tasty and affordable drink made from the sap of Kappaphycus alvarezii seaweed which is readily cultivable. The drink resembles coconut water in appearance and taste and is rich in potassium. It also contains an adequate proportion of the daily requirement of iodine besides many other useful minerals such as magnesium, calcium, sodium, zinc, phosphorous and iron while having low concentrations of toxic elements such as lead and chromium. The process of refining sap, which enables the seaweed drink to be palatable and widely acceptable, besides bestowing adequate shelf life, is also described. The process of preparation is integrated with preparation of carrageenan and plant nutrient thereby making optimum use of the seaweed and minimizing waste.
US08252357B2 Cup shaped baked confectionary and manufacturing method thereof
A cup shaped baked confectionary has light texture, uniform thickness and easy to release from the die. The cup shaped baked confectionary may be produced by mounting a dough of a cup shaped baked confectionary having desired contour shape on a top of a metallic three-dimensional baking die having desired shape of outer peripheral surface, in a condition extending horizontally with placing outer periphery thereof outside of the three dimensional baking die and heating the dough for softening the dough of the cup shaped baked confectionary to contact on the outer peripheral surface of the three-dimensional baking die and baking.
US08252356B2 Flavor composition or fragrance composition
The present invention relates to a flavor composition or fragrance composition which can satisfy diversified requirements for flavored products, as well as to a flavor-improving agent which can improve the quality and release of aroma of a beverage or food. More particularly, the present invention relates to a flavor composition or fragrance composition which comprises an optically active S-alkyl 2-methylbutanethioate as an active ingredient, a flavor- or fragrance-added product, a flavor-improving agent which comprises an optically active S-alkyl 2-methylbutanethioate as an active ingredient, and a beverage or food having an improved flavor. The optically active S-alkyl 2-methylbutanethioate includes S-alkyl(R)-2-methylbutanethioate and S-alkyl(S)-2-methylbutanethioate.
US08252354B2 Manufacture of seed derivative compositions
A method is used to separate fractions from a seed. This can be done by: a) Physically breaking down the Chia seed into smaller particles; b) Adding a liquid carrier to the broken Chia seed to form a Chia liquid carrier blend; c) Optionally providing further processing of the Chia liquid carrier blend to further reduce the particle size of the Chia particles d) Optionally centrifuging the Chia liquid carrier blend; e) Optionally forming at least three discernible layers of materials within the centrifuged Chia liquid carrier blend; f) Optionally separating the composition of at least one layer from remaining layers; and g) Optionally combining the separated layers together into a desired combination/ratios h) Drying the separated layers or combined layers into a flowable powder.
US08252353B2 Custom food product preparation apparatus
Custom food product methods and apparatus are provided that allow customers to participate in the preparation of food products as a part of the dining experience. A method of preparing a custom food product under the direction of a customer includes placing a customer-selected substrate on a scale of custom food product preparation table, placing customer-selected ingredients on the substrate in customer-selected amounts and customer-selected areas, and calculating and displaying the cost of the custom food product to the customer as the customer-selected ingredients are placed on the substrate. Each ingredient is assigned a cost per unit of weight and, as the ingredients are utilized, the cost of the food product is calculated and displayed via a display associated with the table. A customer may be provided with a record of the ingredients of the custom food product and may include an image and/or name of the custom food product.
US08252350B1 Ethanol recovery from fermentation broth
A method of separating an aqueous ethanol mixture from an active ethanol fermentation broth. The method comprising the steps of (a) supplying a selected fraction of the fermentation broth to a first reverse osmosis membrane separation stage to generate a dilute aqueous ethanol permeate and a reduced ethanol content fermentation broth retentate; (b) recycling the reduced ethanol retentate to the active fermentation broth; (c) supplying the aqueous ethanol permeate to a second membrane separation stage to generate a concentrated aqueous ethanol retentate and a dilute aqueous ethanol permeate; and (d) recycling the dilute aqueous ethanol permeate of step (c) to the active ethanol fermentation broth. An additional step of processing the concentrated aqueous ethanol retentate to remove water optionally follows.
US08252348B2 Cosmetic preparation comprising hyaluronic acid
The present invention relates to cosmetic preparations with an active substance combination of hyaluronic acid and saponins.
US08252347B1 Stabilizing and antioxidant composition containing saw palmetto berry component and method of use
A stabilizing and antioxidant composition is prepared from the residue obtained from the saw palmetto berry. The residue from the saw palmetto berry exhibits antioxidant properties that can be used to stabilize various compositions such as food or edible compositions and cosmetics. The saw palmetto residue is also delivered topically or orally to a patient to administer an effective amount of an antioxidant to a patient.
US08252346B2 Natural extract for the control of botrytis cinerea at pre- and post-harvest
Obtaining, producing and using metabolites having anti-botrytis cinerea properties from a natural extract of a native Chilean plant. An in vitro cultivated quillay extract (Quillaza saponaria Mol.), which allows improving the antifungal activity as the result of the enrichment of some secondary metabolites not found in the in vivo plants. Also provided are an in vivo cultivation method, an extraction method, a biocide formulation, and their applications and uses.
US08252343B2 Use of WF10 for treating allergic asthma, allergic rhinitis and atopic dermatitis
The present invention provides a method of inhibiting at least one of allergic asthma, allergic rhinitis and atopic. The present invention further provides a method for the reduction, prevention or treatment of allergy like symptoms in a subject.
US08252342B2 Method for producing complex of metallic nanoparticle and inorganic clay and ethanolamine promoter
A method for producing a complex of metallic nanoparticles and inorganic clay and an organic promoter, wherein the organic promoter is ethanolamine, for example, monoethanolamine (MEA), diethanolamine (DEA) or triethanolamine (TEA). The metallic nanoparticles produced by this method can be stably and uniformly dispersed without adding other reducing agent or dispersant.
US08252338B2 Synthetic LDL as targeted drug delivery vehicle
The present invention provides a synthetic LDL nanoparticle comprising a lipid moiety and a synthetic chimeric peptide so as to be capable of binding the LDL receptor. The synthetic LDL nanoparticle of the present invention is capable of incorporating and targeting therapeutics to cells expressing the LDL receptor for diseases associated with the expression of the LDL receptor such as central nervous system diseases. The invention further provides methods of using such synthetic LDL nanoparticles.
US08252337B2 Charged mesoporous silica nanoparticle-based drug delivery system for controlled release and enhanced bioavailability
A charged mesoporous silica nanoparticle (MSN)-based drug delivery system for controlled release and enhanced bioavailability is disclosed. The system comprises a positively charged MSN, which has a silica matrix and an array of pores and/or nanochannels in the matrix. The entire substance of the matrix, all the surfaces and the pores and/or nanochannels comprise a plurality of silanol (Si—OH) and quaternary ammonium functional groups. The bioavailability of a negatively charged bioactive compound can be increased by loading it into the pores and/or nanochannels. The silanol (Si—OH) functional groups on the surfaces lining the walls of the pores and/or nanochannels are free to deprotonate in a fluid having pH above the pI of the positively charged MSN and lead to a sustained release of the negatively charged drug from the pores and/or nanochannels, and thereby enhance the bioavailability of the drug.
US08252329B2 Bioadhesive drug formulations for oral transmucosal delivery
Bioadhesive drug formulations that adhere to an oral mucosal membrane of a subject are provided together with single dose applicators and devices for delivering the drug formulations to the oral mucosa, and methods for using the same.
US08252328B2 Bioadhesive drug formulations for oral transmucosal delivery
Formulations for controlled delivery of oral transmucosal medications are provided. The formulations are characterized as hydrogel-forming or eroding-types which are bioadhesive and provide for controlled and sustained release of the medication such that enhanced bioavailability and efficacy is provided.
US08252324B2 Drug delivery nanocarriers targeted by landscape phage
A targeted drug delivery nanocarrier and a method of forming the same is disclosed herein. The targeted drug delivery nanocarrier includes a plurality of amphipathic molecules forming a carrier particle having a plurality of drug molecules contained therein. A targeted landscape phage protein assembly is complexed to the carrier particle preferably using the unique method disclosed herein. The targeted landscape phage protein assembly displays a binding peptide that is selected to specifically and selectively bind to a target site. The method for forming targeted drug delivery nanocarriers includes the steps of obtaining a plurality of bacteriophage displaying a binding peptide for a desired target site, treating the bacteriophage with a denaturing agent, mixing the treated bacteriophage with a plurality of carrier particles and purifying the mixture to obtain a plurality of targeted drug delivery nanocarriers.
US08252322B2 Delivery system with increased bioavailability
The present invention is directed to a dry composition which allows delivery of active agents with good bioavailability. These compositions are prepared by emulsifying the active agent using liposome technology known in the art and then encapsulating with a modified starch. The modified starch is prepared by enzymatic hydrolysis of starch after the preparation of a starch derivative containing a hydrophobic group or both a hydrophobic and a hydrophilic group. The resultant composition is a dry powder with excellent bioavailability. Further, the composition has good load levels and stability.
US08252319B2 Transdermal delivery system for sufentanil
Transdermal delivery systems for administering sufentanil through the skin are provided. The systems contain a sufficient amount of sufentanil to induce and maintain a constant state of analgesia when applied to a subject. The systems are characterized as having one or more features including a high degree of dosage form rate control over flux of sufentanil from the system, a high net flux of sufentanil from the system through the skin, lack of a permeation enhancer, an adhesive member demonstrating superior shear time, a low coefficient of variation in the net flux of sufentanil from the system, a high delivery efficiency, and a substantially constant steady state net flux of sufentanil from the system. Methods of using the transdermal delivery systems to administer a sufficient amount of sufentanil to induce and maintain analgesia for extended periods when applied to a subject are also provided.
US08252317B2 Metal alginate hydrogel and articles thereof
The present invention provides novel metal alginates prepared from non-cross-linked alginate monomers such as sodium alginate and an aqueous solution of a group 4, 5, or 6 metal oxyhalide. The novel group 4, 5, and 6 metal alginates are useful in the preparation of cell culture supports, exhibit useful X-ray contrast properties, and exhibit unanticipated stability to standard autoclave conditions relative to known metal alginates such as calcium alginate. In general, the novel metal alginates provided by the present invention offer features and properties not observed in known metal alginates such as calcium or barium alginates.
US08252316B2 Method of topically applying glycopyrrolate solution using absorbent pad to reduce sweating
This invention relates to a convenient and safe product and method of applying glycopyrrolate topically in order to reduce excessive sweating in localized areas for those who suffer from this condition. This invention also relates to combining oral and topical delivery of glycopyrrolate to reduce excessive sweating and minimize side effects. This invention also relates to a convenient and safe product and method of applying glycopyrrolate topically to areas of compensatory sweating after endoscopic thoracic sympathectomy.
US08252313B2 Methods for dietary management of cats with hyperthyroidism
Dietary compositions and methods for restoring normal thyroid function in a feline having hyperthyroidism to a more nearly normal state are disclosed. The compositions and methods restrict the amount of iodine intake in the feline.
US08252310B2 Manufacture process
The present invention relates to a new iron containing phosphate adsorbent and its use e.g. for treating hyperphosphataemia.
US08252307B2 Method for treating and/or preventing retinal diseases with sustained release corticosteroids
The present invention relates to a method for administering a corticosteroid to a posterior segment of an eye. In the method, a sustained release device is implanted to deliver the corticosteroid to the eye. The aqueous corticosteroid concentration remains less than vitreous corticosteroid concentration during release of the corticosteroid from the device.
US08252306B2 Process for preparing a semi-solid delivery vehicle comprising granisetron
A semi-solid delivery vehicle contains a polyorthoester and an excipient, and a semi-solid pharmaceutical composition contains an active agent and the delivery vehicle. The pharmaceutical composition may be a topical, syringable, or injectable formulation; and is suitable for local delivery of the active agent. Methods of treatment are also disclosed.
US08252300B2 Copolymers and their use in personal care compositions
The present invention relates to a copolymer derived from the polymerization of a) at least one cationic monomer of formula (I), where in R1 is hydrogen or methyl, R2 is hydrogen or C1-C4alkyl, R3, R4 and R5 are independently from each other hydrogen or C1-C4alkyl, n is a integer from 1-5, and Y is a counterion, and b) at least one monomer of formula (II) wherein R6 signifies hydrogen or methyl, and R7, R8 and R9 signify independently from each other hydrogen or C1-C4alkyl, with the proviso that at least one of the substituents R6, R7, R8 and R9 and C1-4alkyl and c) optionally at least one cross-linking agent, which contains at least two ethylenically unsaturated moieties, as well as to their use in personal care product and to the personal care products.
US08252297B2 Cosmetic and dermatologic oxygen carrier system
The invention relates to an oxygen carrier system which is suitable for applying gaseous oxygen to the skin in cosmetic and dermatological forms of application. Said system comprises 0.1 to 10 percent by weight of a liquid perfluorinated or partially fluorinated hydrocarbon or hydrocarbon mixture, 10 to 85 percent by weight of a liquid silicone polymer or silicone polymer mixture, and 5 to 25 percent by weight of an oil base or water base, all percentages being in relation to the total weight of the carrier system. Major moieties of the inventive system can be introduced without stability problems especially into silicone oil-containing formulations.
US08252294B2 Methods of screening for compounds that inhibit the biosynthesis of GPI in malaria parasites
The present inventors succeeded in isolating GWT1 (PfGWT1), which is one of the enzymes involved in GPI biosynthesis in the malaria parasite P. falciparum. In addition, the inventors revealed that degenerate mutant DNAs, with a lower AT content than the DNA encoding the PfGWT1 protein, can complement the phenotype of GWT1-deficient yeast. Based on the findings, the present invention provides the GWT1 protein of malaria parasites and the use of the protein in methods of screening for antimalarial drugs. The present invention also provides degenerate mutant DNAs encoding proteins involved in GPI biosynthesis, and which have a lower AT content than the original DNAs. The present invention also provides methods of screening for antimalarial drugs which use the degenerate mutant DNAs.
US08252290B2 Herbal composition for treatment of insomnia and other related disorders and a method of preparing the same
An herbal composition comprises an extract of Radix Rehmanniae, and an extract of Poria, Ganoderma Lucidum, Semen Ziziphi Spinosae, Semen Platycladi, Radix Rehmanniae Praeparata, Radix Angelicae Sinensis, Radix Et Rhizoma Salviae Miltiorrhizae, Rhizoma Chuanxiong, Rhizoma Atractylodis Macrocephalae, Fructus Gardeniae, Cortex Moutan, Radix Bupleuri, Radix Paeoniae Alba, Rhizoma Cyperi, Pericarpium Citri Reticulatae, Fructus Aurantii, Radix Glycyrrhizae, and Os Draconis. The herbal composition is prepared by separately extracting Radix Rehmanniae, and the remaining herbs. The composition is suitable for treatment of insomnia and other related disorders.
US08252286B2 Antagonists of IL-6 to prevent or treat thrombosis
The present invention is directed to therapeutic methods using IL-6 antagonists such as antibodies and fragments thereof having binding specificity for IL-6 to prevent or treat thrombosis in diseases associated with abnormal blood coagulation or fibrinolysis. In preferred embodiments these patients will comprise those exhibiting elevated D-dimer or other coagulation cascade related proteins and optionally will further exhibit elevated C reactive protein prior to treatment. The subject therapies also may include the administration of other actives such as chemotherapeutics, anti-coagulants, statins, et al.
US08252283B2 Method for treating vascular disorders
The invention relates to a method for identifying substances with antiapoptotic activity, where i) cells which express both CD47 and the integrin αvβ3 are cultured, ii) the cells are caused to produce an apoptosis-inducing substance, and/or a substance or substances which induces/induce apoptosis is/are added, iii) the test substance is added, and iv) the apoptosis rate is measured, and to the substances which can be identified with the method.
US08252275B2 Conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates
The present invention provides conjugates having a degradable linkage and polymeric reagents useful in preparing such conjugates. The conjugates as well as the polymeric reagents used to form the conjugates include at least one of each the following: an aromatic moiety comprising an ionizable hydrogen atom, a spacer moiety, and a water-soluble polymer. Methods of making polymeric reagents and conjugates, as well as methods for administering conjugates and compositions, are also provided.
US08252272B2 Hair cosmetic composition
Provided is a hair cosmetic composition containing (A) an amidoamine (1) or an etheramine (2), or a salt thereof, (B) a branched fatty acid (3) or a salt thereof, (C) a silicone, and water: in the formula (1), R1 represents an aliphatic C11-23 hydrocarbon group, R2 represents H or a C1-4 alkyl group, and m stands for a number from 2 to 4; in the formula (2), R3 represents a C6-24 alkyl or alkenyl group, and R4 and R5 each represents a C1-6 alkyl group or a group —(AO)nH, in which A represents a C2-4 alkylene group and n stands for a number from 1 to 6; and in the formula (3), R6 represents a methyl or ethyl group, and p stands for a number from 3 to 36.
US08252271B2 Hair styling compositions containing a silicone elastomer and a non-aqueous polar solvent
A process for styling a keratinous material involving providing a composition containing at least one silicone elastomer, at least one non-aqueous polar solvent, optionally, at least one styling polymer, optionally, at least one emulsifying agent; and a cosmetically acceptable co-solvent, other than the non-aqueous polar solvent; and applying said composition onto the keratinous material.
US08252267B2 DKKL-1 splice product modulators for cancer diagnosis and therapy
The present invention relates to novel sequences for use in detection, diagnosis and treatment of diseases, including cancer. The invention provides novel splice products of human DKKL-1 gene. The present invention provides methods of using polynucleotides having the novel splice products of the human DKKL-1 sequences, their corresponding gene products and modulators of the DKKL-1 splice products for the detection, diagnosis, prevention and/or treatment of associated cancers.
US08252263B2 Device and method for growing diamond in a liquid phase
A method of growing a diamond mass in a liquid growth medium. The liquid growth medium can include a carbon source, a diamond growth catalyst such as a diamond catalyst metal-rare earth element alloy or nanocatalyst, and a dissociated hydrogen of a hydrogen source. The carbon source provides carbon atoms for growing diamond and can include a diamond seed material for diamond growth. The molten liquid phase provides a diamond growth catalyst which allows the carbon to form diamond at the temperature and low pressure conditions discussed. Furthermore, the dissociated hydrogen acts as a concentrator for assembling carbon atoms at a relatively high concentration which mimicks, in some respects, diamond growth under more conventional high pressure processes without the high pressure.
US08252261B2 Process for the preparation of finely divided precipitated silica
The present invention provides a process for the preparation of finely divided precipitated silica. Finely divided precipitated silica is prepared by neutralization of alkali silicate solution, under continuous stirring, at 60° to 90° C. in presence of alkali metal salt as coagulating agent, in various neutralization steps during which neutralization is interrupted for specific time. Further acidic silica sol, is added until 60 to 80% of total alkali is neutralized. The reaction mixture is then aged at least for 3 minute under continuous agitation, followed by circulation through centrifugal pump at an appropriate rate.
US08252260B2 Rare-earth halide single crystals
The invention relates to a method of preparing a polycrystalline block of a halide of formula AeLnfX(3f+e) in which Ln represents one or more rare earths, X represents one or more halogen atoms selected from the group consisting of Cl, Br and I, and A represents one or more alkali metals selected from the group consisting of K, Li, Na, Rb and Cs, e, which may be zero, being less than or equal to 3f, and f being greater than or equal to 1, having a low water and oxyhalide content, in which the method comprises heating a mixture of, on the one hand, at least one compound having at least one Ln—X bond and, on the other hand, a sufficient amount of NH4X in order to obtain the oxyhalide content, resulting in a molten mass comprising the rare-earth halide, the heating being followed by cooling, and the heating, after having reached 300° C., never going below 200° C. before the molten mass has been obtained. The blocks thus produced allow very pure single crystals having remarkable scintillation properties to be grown.
US08252254B2 Process for reduced alkali consumption in the recovery of silver
The present invention is directed to a precious metal recovery process in which basic ferric sulphates and/or jarosites are controlled by hot curing of the autoclave discharge slurry followed by decomposition of argentojarosite using strong acid consumers.
US08252252B2 Processes for the recovery of ruthenium from materials containing ruthenium or ruthenium oxides or from ruthenium-containing noble metal ore concentrates
Processes for the recovery of ruthenium from materials containing ruthenium or ruthenium oxides or from ruthenium-containing noble metal ore concentrates, with the steps of A. the introduction of the material into a highly alkaline alkali hydroxide melt in the presence of nitrate as oxidizing agent with the formation of an oxidized melt residue with water-soluble ruthenate (RuO4)2−, B. the dissolution of the oxidized melt residue obtained in water, C. the addition of a reducing agent, D. the precipitation of the metals formed, can also be used for separating off selenium. Optionally, ruthenium is separated off by distillation, instead of precipitation, following step B, with the steps of 5C the treatment of the ruthenate-containing solution with an oxidizing agent, 5D distilling off of the RuO4 obtained, 5E taking up of the RuO4 from step 5D in hydrochloric acid. By way of further subsequent purification steps, processes for the recovery of ruthenium targets are obtained.
US08252245B2 Partial boiling in mini and micro-channels
The invention provides methods, apparatus and systems in which there is partial boiling of a liquid in a mini-channel or microchannel. The partial boiling removes heat from an exothermic process.
US08252244B2 Method and apparatus of treating waste
A waste treatment system processes waste upon the application of energy. The system includes a vessel that has an open space that receives waste feedstock. At least two plasma electrodes are mounted to the vessel. An electrode movement control system may position the plasma electrodes to facilitate a pryolysis process to treat the waste feedstock.
US08252240B2 Multiple loop reactor for olefin polymerization
The present invention provides a multiple loop reactor suitable for polymerizing olefins comprising at least two interconnected loop reactors, whereby said connection essentially consists of one or more transfer lines suitable for transferring polymer slurry from a reactor to another reactor and whereby said transfer line extends substantially horizontally. The invention further relates to a process for producing olefin polymers in a multiple loop reactor according to the invention. The invention also relates to the use of a transfer line for transferring polymer slurry from a reactor to another reactor in a multiple loop reactor comprising at least two interconnected loop reactors, whereby said transfer line extends substantially horizontally.
US08252238B2 Air purification system and method for cleaning air
Air purification systems comprising a plurality of disks, and methods for their use, are provided. Each of the plurality of disks comprises a metal substrate, an undercoat layer disposed on the metal substrate, a photosensitive layer disposed on the undercoat layer, and a charge transfer layer disposed on the photosensitive layer.
US08252234B2 Apparatus for producing a pharmaceutical product
An apparatus is provided for producing pharmaceutical and pharmaceutical-like product. The apparatus provides real-time monitoring of the pharmaceutical product and can provide real-time control. The apparatus monitors the dosage both before and after it has been added to a carrier substrate. The apparatus can provide monitoring of each pharmaceutical product that is processed.
US08252233B2 Automatic analyzer and sample-processing system
A sample-processing system that improves total system processing efficiency, and reduces a sample-processing time, by establishing a functionally independent relationship between a rack conveyance block with rack supply, conveyance, and recovery functions, and a processing block with sample preprocessing, analysis, and other functions. A buffer unit with random accessibility to multiple racks standing by for processing is combined with each of multiple processing units to form a pair, and the system is constructed to load and unload racks into and from the buffer unit through the rack conveyance block so that one unprocessed rack is loaded into the buffer unit and then upon completion of process steps up to automatic retesting, unloaded from the buffer unit. Functional dependence between any processing unit and a conveyance unit is thus eliminated.
US08252229B2 Method and system for sterilizing an analyte sensor
In one aspect, there is provided assembling an analyte sensor with an analyte sensor insertion device, packaging the assembled analyte sensor and sensor insertion device in a substantially airtight seal, and irradiating the packaged assembled analyte sensor and sensor insertion device at a predetermined dose using one or more electron beam accelerators.
US08252228B1 Methods for sterilizing carriers for treatment of a kidney
A kit is described including at least one container including a predetermined quantity of sterilized biodegradable carriers in a powder form having a treatment agent disposed therein. The kit further includes a delivery device for delivering the predetermined quantity of sterilized biodegradable carriers with the treatment agent disposed therein to a treatment site. In other embodiments, methods are described for producing the sterilized treatment agent loaded biodegradable carriers and delivering the sterilized carriers to a treatment site.
US08252225B2 Methods of forming erosion-resistant composites, methods of using the same, and earth-boring tools utilizing the same in internal passageways
A multi-layer precursor material for use in forming hardfacing on a tool including hard particles, metal particles and a polymer. Methods of forming a multi-layer precursor film. Methods of using a precursor material to form hardfacing on a tool, including brazing a precursor material onto a surface of the tool. Intermediate structures for use in forming earth-boring tools including a precursor material covering an internal surface of a body of the tools. Methods of forming earth-boring tools include forming a body having a fluid passageway extending therethrough and covering a surface of the body with a hardfacing material. The surface of the body may be located in a region susceptible to erosion when fluid is caused to flow through the fluid passageway.
US08252224B2 Methods of assembling multi-layered drink-containers
Multi-layered drink-containers including an inner liquid-container and an outer shell in an at least partially overlapping, telescopic relation relative to the inner-liquid-container and methods of assembling the same. In some examples of multi-layered drink-containers, the inner liquid-container includes a lower portion having an outer cross-sectional area, an orthogonal projection of which at least partially overlaps an orthogonal projection of an inner cross-sectional area of an upper portion of the outer shell. Some examples of methods of assembling multi-layered drink-containers include reducing a resiliently deformable restrictive-portion of an inner liquid-container, positioning an outer shell in an at least partially overlapping, telescopic relation relative to the inner liquid-container, and returning the resiliently deformable restrictive-portion to a neutral, un-deformed and un-reduced state. In some methods, the reducing includes applying a vacuum to the internal volume of the inner liquid-container.
US08252221B2 Compacting techniques for forming lightweight concrete building blocks
A lightweight concrete mixture (e.g., comprising cement and polystyrene foam) is introduced into a compactable mold having a mold cavity defined by plural wall structures including at least two compacting wall structures. After introducing the lightweight concrete mixture into the compactable mold, the compacting wall structures are moved such that the lightweight concrete mixture is compacted in the mold cavity. The respective positions of the plural compacting wall structures can be maintained during curing of the lightweight concrete mixture such that the lightweight concrete mixture is held under compression during curing. A compactable mold may also include one or more tubes for forming tube-shaped cavities within a building block formed in the mold. Tubes can form intersecting cavities within the building block. Tubes can remain stationary while the compacting walls are moved, even when the tubes are attached to a compacting wall.
US08252218B2 Porous film manufacturing method and successive biaxial stretching apparatus for manufacturing porous film
Provided is a method for manufacturing a high-quality porous film. Here, while the porous film is being manufactured through forming micropores by stretching, a raw film is prevented from slipping on the surfaces of the respective rolls as much as possible even though the raw film includes oil or liquid paraffin as a solvent. The method is for manufacturing a porous film through forming micropores by successive biaxial stretching. A tensile force applied to the raw film F transferring from the longitudinal stretching machine (10) to the transverse stretching machine (50) is set not less than a stretching force necessary for the longitudinal stretching, and thus the raw film is prevented from slipping on a contact surface between the raw film and each roll of the longitudinal stretching machine (10).
US08252213B2 Denture flask mould press and method of use
In preparing dentures, hardened mould material surrounds the denture. This mould material is adhered inside a denture flask with a housing having two separably matable portions. To remove the hardened mould material from the flask, the flask is mounted in a mould press having a shaft, with one of the portions is restrained against movement along an axis of travel of the shaft. A portion of the mould material at an end of the restrained flask portion is available for contact with the shaft along the axis of travel. A capped end of the shaft is forcefully advanced against the adhered mould material therein, thereby breaking the adhesion. After this is done, the denture flask is dismounted from the mould press and the hardened mould material is removed from the first flask portion. If necessary, the process is repeated with the other housing portion.
US08252210B2 Method and device for explosion forming
With the invention, a method and a device for explosive forming of work pieces, in which at least one work piece is arranged in at least one die and there deformed by means of an explosive to be ignited, is to be improved, in that an ignition mechanism that is technically easy to handle is produced with the shortest possible setup times, which permits the most precise possible ignition of the explosive with time-repeatable accuracy. This task is solved by a method and device, in which at least one work piece is arranged in at least one die and deformed there by means of an explosive being ignited, in which the explosive is ignited by means of at least one energy beam.
US08252207B2 Ink for inkjet recording, ink set for inkjet recording, ink media set for inkjet recording, ink cartridge, inkjet recording method, and inkjet recording apparatus
To provide an ink for inkjet recording containing water, water-soluble organic solvent, water-dispersible resin, fluorochemical surfactant or derivative thereof, and coloring agent containing pigment, wherein the ink has a surface tension of 20-35 mN/m and viscosity of 5 mPa·s or more at 25° C., total amount of the water-dispersible resin and the coloring agent in the ink is 5-40% by mass, and mass ratio A/B of the water-dispersible resin A to the coloring agent B is 0.5-4, wherein the ink is applied for a recording medium for inkjet recording containing a support containing cellulose pulp, and one or more barrier layers disposed on at least one face of the support, and wherein the barrier layer contains 30% by mass or more of inorganic pigment having refractive index of 1.5 or more, excluding aluminum hydrate, and 10% by mass or less of an inorganic pigment having a refractive index of less than 1.5.
US08252206B2 Amorphous film of composite oxide, crystalline film of composite oxide, method of producing said films and sintered compact of composite oxide
Provided is an amorphous film comprised substantially of indium, tin, magnesium and oxygen, and containing tin at a ratio of 5 to 15% based on an atomicity ratio of Sn/(In+Sn+Mg) and magnesium at a ratio of 0.1 to 2.0% based on an atomicity ratio of Mg/(In+Sn+Mg) with remnant being indium and oxygen, and having a film resistivity of 0.4 mΩcm or less as a result of crystallizing the film by annealing the film at a temperature of 260° C. or lower. An amorphous ITO thin film for use as a display electrode and the like in flat panel displays is obtained by way of sputter deposition without heating the substrate and without the need of adding water during the deposition. This amorphous ITO film has the property of being crystallized by annealing at 260° C. or lower, which is not such a high temperature, and having low resistivity after crystallization. Also provided are a method of producing the film and a sintered compact for producing the film.
US08252203B2 Luminescent material
A luminescent material is disclosed. The luminescent material may include a first compound having a host lattice comprising first ions and oxygen. A first portion of the first ions may be substituted by copper ions. In one embodiment, the host lattice may include silicon, the copper ions may be divalent copper ions and the first compound may have an Olivine crystal structure, β-K0.2SO4 crystal structure, a trigonal Glaserite (K3Na(SO4)2) or monoclinic Merwinite crystal structure, a tetragonal Ackermanite crystal structure, a tetragonal crystal structure or an orthorhombic crystal structure. In another embodiment, the copper ions do not act as luminescent ions upon excitation with the ultraviolet or visible light.
US08252202B2 Nematic liquid crystal composition and bistable nematic liquid crystal display
A nematic liquid crystal composition of the present invention includes at least 20% by weight of one, or two or more compounds selected from compound group A; and 5 to 50% by weight of one, or two or more compounds selected from compound group B, wherein the relative proportions of the above-mentioned compounds used in the nematic liquid crystal composition is determined to simultaneously obtain the specific physical characteristics for the composition, and an anchoring breaking voltage Uλ/4 is less than or equal to 25 V when the product (Δn·d) of the refractive index anisotropy (Δn) at 20° C. and the thickness (d) is 140 nm and the liquid crystal composition is confined between two substrates for a bistable nematic liquid crystal display in which at least one of the substrates have a weak zenithal anchoring force.
US08252200B2 Coated calcium hypochlorite composition
The present invention is directed to a water treatment composition, comprising: calcium hypochlorite coated with a coating comprising at least one hydrated or anhydrous salt. The present invention is also directed to a water treatment composition, comprising: (a) an inner core layer comprising calcium hypochlorite; (b) one or more interlayers of selected salts positioned on top of said inner core layer, and (c) one or more outer layers of selected salts positioned on top of said interlayer(s).
US08252198B2 Hydrofluoroolefin compositions
The present invention relates to compositions containing hydrofluoroolefins and to the uses thereof as heat transfer fluids, blowing agents, solvents and aerosols. More particularly, the invention relates to compositions having from 5 to 65% by weight, preferably from 5 to 15% by weight, of 2,3,3,3-tetrafluoropropene, 5 to 70% by weight, preferably 40 to 60% by weight, of HFC-134a and 25 to 42% by weight of HFC-32.
US08252196B2 Method for preparing nanotubes of piezoelectric material and nanotubes of piezoelectric material obtained thereby
A method for preparing nanotubes by providing nanorods of a piezoelectric material having an asymmetric crystal structure and by further providing hydroxide ions to the nanorods to etch inner parts of the nanorods to form the nanotubes.
US08252195B2 Methods and compositions for acid treatment of a metal surface
The invention relates to compositions and methods that are useful in etching a metal surface. In particular, the invention relates to novel acid compositions and methods of using such compositions in etching a metal surface, preferably an aluminum surface prior to anodizing to dissolve impurities, imperfections, scale, and oxide. The compositions are effective in maintaining their etching capacity and in removing smut produced by the etching of a surface as well as in general cleaning.
US08252194B2 Methods of removing silicon oxide
A method of removing at least a portion of a silicon oxide material is disclosed. The silicon oxide is removed by exposing a semiconductor structure comprising a substrate and the silicon oxide to an ammonium fluoride chemical treatment and a subsequent plasma treatment, both of which may be effected in the same vacuum chamber of a processing apparatus. The ammonium fluoride chemical treatment converts the silicon oxide to a solid reaction product in a self-limiting reaction, the solid reaction product then being volatilized by the plasma treatment. The plasma treatment includes a plasma having an ion bombardment energy of less than or equal to approximately 20 eV. An ammonium fluoride chemical treatment including an alkylated ammonia derivative and hydrogen fluoride is also disclosed.
US08252189B2 Nano structure fabrication
A method for manufacturing a nano structure includes forming a stamp having a line pattern on a surface thereof, positioning the stamp upon a substrate, forming at least one protruded portion in the substrate substantially corresponding to the line pattern of the stamp, forming a protective coating layer on at least a portion of the at least one protruded portion, and removing a portion of the substrate by etching at least another portion of the at least one protruded portion not covered with the protective coating layer.
US08252184B2 Method, equipment and specific drawer for membrane separation utilizing concentration polarization
The present invention relates to a membrane separation method and a relevant equipment, in particular to a method and an equipment for membrane separation utilizing concentration polarization during membrane filtration process, especially, to a concentration process and equipment and a drawer special for drawing a concentration polarization layer. The direct removal of the concentration polarization layer from membrane surface not only decreases the adverse influence of concentration polarization on membrane separation but also obtains concentrated retention components, thereby significantly improving the ability to maintain membrane flux, solving the twinborn problems concerning concentration polarization and membrane fouling during the membrane separation process, and achieving a high-efficiency concentration for retention components. The method and equipment of the present invention can be widely applied in various membrane techniques, in particular in a membrane separation process for concentrating biomacromolecule and organic micromolecule products such as sugars, organic acids and polypeptides etc.
US08252180B2 Tank
A tank for water-carrying appliances is proposed, in particular domestic appliances or appliances for the treatment of foods and/or beverages, such as beverage vending machines, in particular coffee vending machines, drinking water dispensers, cooking and baking appliances, steam appliances, in particular steam irons, steam cleaners, high-pressure cleaners, air purifiers and conditioners or the like, a suction connection on the tank for the intake of water from the tank, with means for generating a vacuum, and a filter connection for connecting a filter cartridge inside the tank being provided, while it is ensured that only one permitted filter type is used. A tank according to the invention is characterized by mechanical coding structures at the filter connection element in order to exclude the use of a filter cartridge which does not correspond to the tank.
US08252179B2 Solid-liquid separator
A liquid cyclone is configured for inflowing raw water containing impurities as targets of collection to be forced to swirl inside to spin down impurities contained in raw water, an inflow pipe is connected with an upper portion of the liquid cyclone to supply the liquid cyclone with raw water, and configured for supplied raw water to be forced to swirl inside the liquid cyclone, a connecting portion is connected with a lower portion of the liquid cyclone, and configured with a discharge port to discharge spun down impurities from the liquid cyclone, an impurity collector is connected to the liquid cyclone with the connecting portion in between, and configured to collect impurities discharged from the liquid cyclone, an obstacle is disposed in or near the discharge port, , and configured to prevent impurities collected in the impurity collector from backing up into the liquid cyclone, and an outflow pipe is connected with a top portion of the liquid cyclone, and configured for raw water having got rid of impurities to outflow as treated water from the liquid cyclone, whereby impurities separated from raw water is prevented from being re-mixed in raw water, allowing for an enhanced separation performance.
US08252178B2 Magnetic treatment of fluids
Magnetic treatment units are comprised of a body (21) having a central aperture, and having a pair of recesses (28) on opposite sides of the central aperture for inserting and retaining magnets (22) when covered by sleeve (23). The magnets (22) are flat magnets that have their poles on their flat sides, and are inserted into the recesses (28) such that the north pole of one magnet faces the south pole of the other magnet in the opposite recess. The invention also provides for a magnetic treatment assembly (10) for insertion into a pipe (11) or open channel comprising baffle plate (14) having a plurality of apertures (18) of which some have magnetic treatment units (15) attached to them such that the magnetic treatment units (15) are regularly spaced about baffle plate, and orientated so that north and south poles of magnets (22) in adjacent magnetic treatment units (15) are aligned.
US08252174B2 Vehicle-integrated water harvesting system
A vehicle-integrated water harvesting system is provided that enables water-vapor or condensation in a vehicle to be captured, and made available onboard the vehicle for drinking or other uses. The system includes a water emitting component and may include a purification system operatively connected to the water emitting component. The purification system at least partially purifies the water and then sends the purified water to a storage reservoir or directly to a dispenser or outlet.
US08252173B2 Water filter cartridge system having a combined blending valve system in the candle and adjusting device in the head
The present invention relates to a water filter, having a filter head and an interchangeable filter cartridge, with a blend-adjusting element which is located on the filter cartridge. The water filter is distinguished in that during the operation of installing the interchangeable filter cartridge in the filter head, the blend-adjusting element is positioned together with the filter cartridge on the filter head via adjustable or fixed drivers. In a further embodiment, the water filter is distinguished in that an adjusting device comprises an untreated-water distribution element arranged in or on the filter head and a partial-flow channel guiding element which is complementary with respect thereto and is arranged in or on the filter cartridge.
US08252171B2 Water purification, enhancement, and dispensing appliance
A water purifying and enhancement system of a modular construction designed as a built-in appliance located under the countertop or as a free-standing (stand alone) unit. The water appliance has a water inlet for obtaining water from a supply source, scale reduction device, booster or re-pressurization pump, pre-filtration, U.V. sterilization, R.O. filtration, de-ionization (CDI or mechanical), mineral injection system (for adding desired minerals into the purified water), water diagnostic and monitoring cells, post filtration, proprietary water enhancement reactor consisting of specially engineered and blended ores of ceramic components, and/or an electrolytic ionization chamber, and/or a magnetic chamber, a water outlet for delivery of the highly purified enhanced water product, and a outlet to grey water drain for reject water. Control and monitoring instrumentation implemented into the front panel of the water appliance will continuously provide monitoring of water quality, filter life, filter maintenance, system failure indicators, and other pertinent diagnostic data.
US08252159B2 Microfluidic device for controlled movement of liquid
The invention concerns a microfluidic device for the controlled movement of liquid. The controlled-movement device according to the invention comprises a microchannel (10) filled with a first liquid (F1) and a fluid (F2) forming a first interface (I1) with the first liquid (F1), or forming a first interface (I1) with the first liquid (F1) and a second interface (I1) with a second liquid (F3) situated downstream of said fluid (F2), and means of moving the first liquid (F1) by electrowetting. A control system is provided for controlling the movement of the first liquid (F1) according to the position of an interface (I1, 13) of the fluid (F2).
US08252158B2 Oxygen sensors
An electrochemical oxygen sensor includes a micro-porous plastic membrane supported on a sealing disk and located between a gas inflow port and the sensor's electrolyte. The membrane and disk minimize thermal shock effects due to using the sensor at a first location, at a first temperature, and then moving it to a second location at a different temperature.
US08252153B2 Patterned-media perpendicular magnetic recording disk with servo regions having magnetized servo pillars and oppositely-magnetized servo trenches
A patterned perpendicular magnetic recording disk has a pre-patterned disk substrate with pillars and trenches arranged in data regions and servo regions. In the data regions, the height of the data pillars is equal to or greater than the spacing between the data pillars, while in the servo regions the height of the servo pillars is less than the spacing between the servo pillars. A magnetic recording material with perpendicular magnetic anisotropy is deposited over the entire disk substrate, which results in magnetic material on the tops of the data pillars and servo pillars and in the servo trenches. The material in the data trenches is either nonmagnetic or discontinuous. After the application of a high DC magnetic field in one perpendicular direction and a low DC magnetic field in the opposite direction, the resulting disk has patterned servo sectors with servo pillars all magnetized in the same perpendicular direction and servo trenches magnetized in the opposite perpendicular direction.
US08252150B1 Extractive distillation process for recovering butadiene from C4 hydrocarbon mixtures
High purity 1,3 butadiene is recovered from a C4 fraction containing butadienes, butenes, butanes, and acetylenes that is generated from a steam cracker by extractive distillation operating with no reflux or greatly reduced reflux conditions. This no reflux (or minimum reflux) technique is generally applicable to any butadiene recovery process in which at least one extractive distillation column (EDC) is used to separate 1,3 butadiene from other C4 components in the mixture. For an ED process with two EDCs, significant reductions in total energy requirements in the both EDCs can be achieved by appropriate reductions in the reflux in each column. The performances of both EDCs are unaffected even when operating at no reflux.
US08252142B2 Use of a surface-reacted calcium carbonate in tissue paper, process to prepare a tissue paper product of improved softness, and resulting improved softness tissue paper products
The present invention relates to the use of a surface-reacted natural calcium carbonate as filler in tissue paper products, to a process to prepare tissue paper products, and to a tissue paper product featuring an improved softness, wherein said surface-reacted natural calcium carbonate is the reaction product of a natural calcium carbonate with an acid and carbon dioxide, which is formed in situ by the acid treatment and/or supplied externally.
US08252138B2 Thermosensitive multiple recording sheet and method for producing the same
The present invention provides a thermosensitive multiple recording sheet characterized in that a second base material having light transmission properties is attached to the side of a first thermosensitive recording layer of a first thermosensitive recording sheet comprising a first base material and the first thermosensitive recording layer formed on one surface of the first base material, through a temporary adhesive layer, the second base material is composed of an information disclosing portion and an information non-disclosing portion, a shielding layer is formed at the position corresponding to the information non-disclosing portion on the second base material, and an ultraviolet curable resin layer are formed as an outermost layer of the sheet.
US08252137B2 Building panel having plant-imitating structural core
A building or structural panel has a core and outer skins. The core is formed from a stack of layers of building stock such as plywood. Multiple layers of building stock are connected, such as by adhesive at spaced intervals along the lengths thereof to form a stack. The stack is cut into a plurality of strips. Each strip is expanded to form the core. The core comprises a matrix of supporting elongate members and voids or openings. Skins are connected to each side of the core, such as with adhesive, to form the panel. The panel may be cut to size. Anchors or other mounts may be connected to panel.
US08252131B2 Reworking ceramic structures
A method for reworking a ceramic structure. A number of holes are formed in a portion of the ceramic structure in which a rework of the ceramic structure is desired. The ceramic structure has a plurality of layers in the portion in which the rework is desired. A ceramic bonding material is introduced into the number of holes formed in the portion of the ceramic structure. The ceramic bonding material is cured in the portion of the ceramic structure.
US08252124B2 Powder magnetic core and method for manufacturing the same
The present invention provides a powder magnetic core low in the loss and high in the saturation magnetic flux density and a method for manufacturing the same. More specifically, the present invention provides a powder magnetic core that comprises a soft magnetic metal powder having an average particle size (D50) of 0.5 to 5 μm, a half width of diffraction peak in a <110> direction of α-Fe as measured by X-ray powder diffraction of 0.2 to 5.0°, and an Fe content of 97.0% by mass or more, the core having an oxygen content of 2.0% by mass or more.
US08252121B2 Drain system for a warewasher
A warewasher for washing wares includes a chamber for receiving wares. The chamber has an associated liquid delivery system for spraying liquid onto wares within the chamber. A tank collects the sprayed liquid. A liquid recirculation system moves liquid from the tank back to the liquid delivery system. A drain system is located within the tank. The drain system includes a well, a liquid recirculation system inlet within the well and a drain opening within the well. A drain control assembly includes a drain stopper member and a strainer connected with the drain stopper member. When the drain stopper member is positioned to block flow through the drain opening, the strainer is positioned to block passage of tableware into the well. The strainer is mounted for sliding movement along a length of the drain stopper member enabling, when the drain stopper member is raised slightly to permit flow out of the drain opening, the strainer to remain in position to block passage of tableware into the well.
US08252120B2 Washing apparatus, a method of purifying a wash material and use of the washing apparatus
The invention relates to a washing apparatus, including a First Region (1) to which a wash material (4) is supplied, a Second Region (2), in which the wash material (4) is washed, and a Third Region (3), in which the wash material (4) is melted and a flow resistance (6), which is provided between the Second Region (2) and the Third Region (3), a purification apparatus, a synthesis device, a method for purifying a wash material, and the use of a washing apparatus or a purification apparatus for purifying and then using the target product obtained by the purification.
US08252119B2 Microelectronic substrate cleaning systems with polyelectrolyte and associated methods
Several embodiments of cleaning systems using polyelectrolyte and various associated methods for cleaning microelectronic substrates are disclosed herein. One embodiment is directed to a system that has a substrate support for holding the microelectronic substrate, a dispenser positioned above the substrate support and facing a surface of the microelectronic substrate, a reservoir in fluid communication with the dispenser via a conduit, and a washing solution contained in the reservoir. The washing solution includes a polyelectrolyte.
US08252117B2 Automatic feed system and related process for introducing source material to a thin film vapor deposition system
A feed system and related process are configured to continuously feed measured doses of source material to a vapor deposition apparatus wherein the source material is sublimated and deposited as a thin film on a substrate. The system includes a bulk material hopper, and an upper dose cup disposed to receive source material from the hopper. A lower dose cup is disposed in a vacuum lock chamber to receive a measured dose of source material from the upper dose cup. A transfer mechanism is disposed below the vacuum lock chamber to receive the measured dose of source material from the lower dose cup and to transfer the source material to a downstream deposition head while isolating the deposition conditions and sublimated source material within the deposition head.
US08252112B2 High speed thin film deposition via pre-selected intermediate
A method and apparatus for the unusually high rate deposition of thin film materials on a stationary or continuous substrate. The method includes delivery of a pre-selected precursor intermediate to a deposition chamber and formation of a thin film material from the intermediate. The intermediate is formed outside of the deposition chamber and includes a metastable species such as a free radical. The intermediate is pre-selected to include a metastable species conducive to the formation of a thin film material having a low defect concentration. By forming a low defect concentration material, deposition rate is decoupled from material quality and heretofore unprecedented deposition rates are achieved. In one embodiment, the pre-selected precursor intermediate is SiH3. The method further includes combining the pre-selected precursor intermediate with a carrier gas, preferably in a deactivated state, where the carrier gas directs the transport of the pre-selected precursor intermediate to a substrate for deposition of the thin film material.
US08252110B2 Lightweight plasterboard and plaster slurry composition used for its manufacture
A plaster slurry composition includes plaster, water and starch, the starch having a Brookfield viscosity of less than 60 cps at a temperature below 60° C. and a Brookfield viscosity greater than 10,000 cps at a temperature of 70° C.
US08252108B2 Light-weight composition and mix for masonry, mortar and stucco
An application for a pre-mixed mortar, stucco or masonry composition includes a approximately 75% sand and 25% of a light-weight cement mix comprising a cement (either Portland cement or hydraulic cement), fly ash, sodium tall oil, sodium stearate, sodium C14-16 Alpha Olefin, linear alkyl benzene; and silicon dioxide.
US08252107B2 System and method for treating tailings from bitumen extraction
A system and method for treating tailings from a bitumen froth treatment process such as TSRU tailings. The tailings are dewatered and then combusted to convert kaolin in the tailings into metakaolin. Calcined fines and heavy minerals may be recovered from the combustion products, namely from the flue gas and bottom ash.
US08252106B2 Modifier for concrete and cement formulations and methods of preparing the same
Disclosed are wax emulsion modifiers for concrete and cement formulations and methods for preparing same. The modifiers are applicable to pervious concrete, used in residential areas, parking lots and parks to more effectively manage storm waters and improve environmental practices. This invention also relates to conventional Portland cement concrete mix designs with little to no sand, which provide improved workability, low hydration rates without sacrificing strength while achieving high levels of porosity for water transmission.
US08252103B2 Water-based ink for ink-jet recording, ink cartridge, and ink-jet recording apparatus
The present invention provides a water-based ink for ink-jet recording containing a coloring agent and water. The coloring agent contains a dye represented by the following general formula (1). The ink further includes a substance having a structure in which a carbon atom and a nitrogen atom are covalently bound.
US08252102B2 Water-based black ink for ink-jet recording, ink cartridge, and ink-jet recording apparatus
The present invention provides a water-based black ink for ink-jet recording, containing a coloring agent and water. The coloring agent contains a yellow dye, a magenta dye, and a cyan dye. The yellow dye contains a dye (Y) represented by the following general formula (1). The magenta dye contains a dye (M) represented by the following general formula (2). The cyan dye contains a phthalocyanine dye (C). The dye (Y), the dye (M), and the phthalocyanine dye (C) are blended so as to satisfy the following conditions (a) and (b). (a) Y:M (weight ratio)=about 2:3 to about 3:2 (b) (Y+M):C (weight ratio)=about 2:1 to about 2:3
US08252101B1 Method and composition for polishing surfaces
The invention is a method and composition for polishing a wet surface. The invention is a water based composition for polishing wet surfaces and a method of applying the water based composition to polish wet surfaces. The method does not include a dry to haze or buffing step in order to achieve a lasting high gloss shine on the polished surface.
US08252100B2 Air filtration device
An air purifier has a housing with an inlet for receiving air and an outlet for exhausting air. The housing provides an air flow path for the flow of air in a downstream direction, from the inlet towards the outlet. Particulate pre-filtration is located within the housing downstream from the air inlet. VOC pre-filtration is located within the housing downstream from the particulate pre-filtration. UV filtration is located within the housing downstream from the VOC pre-filtration. VOC post-filtration is located within the housing downstream from the UV filtration. Final particulate filtration is located within the housing downstream from the VOC post-filtration.
US08252095B2 Filter media for active field polarized media air cleaner
Filter media for an active field polarized media air cleaner includes two layers of dielectric material with a higher resistance air permeable screen sandwiched between the lower resistivity electric layers. The filter media may further include a mixed fiber filter layer having fibers from different sides of the triboelectric scale. The filter media may further include a layer of relatively higher density dielectric material followed by a layer of relatively lower density dielectric material.
US08252094B2 Gas exchange membrane in particular for use in an artificial lung and method for the production of a gas exchange membrane of this type
A gas exchange membrane is for use in an artificial lung. The membrane consists of a foamed, closed-cell material, in particular of silicone rubber. The membrane is produced by extruding a basic material which contains a foaming agent. The extrudate is then foamed. The result is a gas exchange membrane which has an increased gas exchange performance compared to known material due to the high permeability of the surface.
US08252090B2 Process and apparatus for providing an inert gas to a large volume atmosphere
A system and method is presented for reducing a concentration of ambient air used in a feed stream to form an inerting gas in a pressure swing adsorption system. The method includes introducing ambient air into a pressure swing adsorption system to form an inerting gas, introducing the inerting gas to a large volume of atmosphere, thereby inerting at least a portion of the large volume of atmosphere to form an inerted atmosphere, and removing a portion of the inerted atmosphere and introducing the portion of inerted atmosphere to the pressure swing adsorption system to form the inerting gas, thereby reducing an amount of ambient air utilized to form the inerting gas in the pressure swing adsorption system.
US08252089B2 Method and device for drying a gas flow rich in carbon dioxide
The present invention relates to a method and device for compressing and drying a gas flow rich in carbon dioxide, for example containing more than 50 mol % of carbon dioxide.
US08252086B2 Extraction of metals from sulphide minerals
Nickel entrained in the sulphide mineral pyrrhotite is engineered to dissolve in leaching acid in a two step procedure. First, a slurry of the mineral and the acid is activated by oxidation. This is done in a time T1 by electrolysis; or alternatively chemically, by adding e.g an oxidizing acid to the mineral. After activation, the slurry is then kept under anoxic conditions for a time T2. During T2, the sulphide starts to dissolve much more rapidly, and the rapid breakdown of the sulphide enables the nickel to dissolve and thus to be leached out of the mineral. The dissolved nickel is extracted from the leaching acid e.g by electro-winning.
US08252080B2 Liquid absorbing filter assembly and system using same
A filter assembly for use in sidestream gas sampling assembly. The filter assembly of the present invention includes a hydrophilic. The filter further includes a Hydrophobic member positioned downstream of the hydrophilic liner. The hydrophobic disk acts as a second line of defense against moisture reaching the sensing mechanism member that is constructed from a porous material and is situated such that gas entering the filter assembly passes through at least a portion the hydrophilic member. In a further embodiment, the filter includes a hydrophobic member positioned downstream of the hydrophilic member. The hydrophobic member acts as a second line of defense against moisture reaching the sensing mechanism in the gas sampling assembly.
US08252074B2 Method of operating a fixed bed dry bottom gasifier
Method of operating a fixed bed dry bottom gasifier includes feeding coarse particulate coal with an average particle size of at least 1 mm and an ash fusion temperature increasing agent into a gasification chamber of the gasifier to form a coal bed, feeding a gasification agent into the gasification chamber, and gasifying the coarse particulate coal in the gasification chamber to produce synthesis gas as well as ash. The ash is collected in an ash bed below the coal, and the synthesis gas and the ash are removed from the gasification chamber.
US08252067B2 Quick-release computer access cover
A latch and latch handle recessed into the computer cover is provided, with the latch handle preferably presently a cam surface internally that interacts with a compatible cam surface associated with a lock bar. Preferably, a key lock is functionally integrated with the latch in such a way that when the key lock is unlocked the latch handle and latch are free to displace and to then urge the retention bar to disengage detents or hooks from slots or receptacles, by way of releasing the cover from a chassis or body of the desktop or workstation. Accordingly, in essentially one efficient movement via engaging the latch handle, a user will be able to quickly remove the cover.
US08252064B2 Fiber-reinforced composite absorbable endoureteral stent
Absorbable/disintegratable endourological stents, specifically endoureteral stents, and applicators for their introduction into the biological site, are formed from fiber-reinforced elastomeric films configured to prevent their migration from the application site.
US08252057B2 Surgical access device
A surgical access device comprises a conduit comprising a proximal portion and a distal portion. An inflatable member at least partially surrounds a portion of the conduit and is positioned proximate to the distal portion of the conduit. In various embodiments, a protective sleeve can at least partially surround a portion of the conduit and is movable between at least a first position and a second position. In at least one embodiment, the protective sleeve is configured to at least partially cover the inflatable member when in the first position and is configured to expose the inflatable member when in the second position.
US08252056B2 Biocompatible osteogenic band for repair of spinal disorders
Methods of repairing a joint formed by at least two bone sections are provided wherein a biocompatible osteogenic band fabricated from an osteogenic biological material such as bone, tendon, ligament and collagen is affixed to two or more bone sections.
US08252055B2 Synthetic loadbearing collagen-mineral composites useful for spinal implants, and methods of manufacture
Described are intervertebral spinal implants that include a biocompatible load bearing composite comprised of a particulate mineral material and collagen and having a wet compressive strength of at least about 200 N/cm2. The composite provides a load bearing body sized and shaped for insertion between adjacent vertebrae in a patient. The load bearing body has upper and lower surfaces configured to frictionally engage the adjacent vertebra. Also described are related methods of making and using the spinal implants, and other bone implants comprising the strong composites made available in the present invention.
US08252054B2 Expandable support device and method of use
An expandable support device and methods of using the same are disclosed herein. The expandable support device can expand longitudinally. The expandable support device can be deployed in a bone, such as a vertebra, for example to repair a compression fraction or replacement of removed tissue, such as a vertebra or vertebral body. The expandable support device can be deployed into or in place of all or part of an intervertebral disc.
US08252051B2 Method of implanting a prosthetic valve in a mitral valve with pulmonary vein anchoring
A method of implanting a prosthetic mitral valve assembly is disclosed. The prosthetic mitral valve assembly includes a stent and valve combination. The prosthetic mitral valve assembly is provided with an anchoring portion adapted to be positioned in the left atrium. In one embodiment, the anchoring portion includes at least one anchoring arm sized for placement in a pulmonary vein. The stent is radially expandable so that it can expand into position against the walls of the left atrium and accommodate a wide range of anatomies. Contact between the stent and the native tissue in the left atrium reduces paravalvular leakage and prevents migration of the stent once in place.
US08252049B2 Method for therapy of heart valves with a robot-based X-ray device
A method or workflow for heart valve replacement, or more precisely emplacement of a prosthetic heart valve, using minimally invasive procedures includes imaging of the patient's heart during the procedure using a multi-access articulated x-ray imaging robot that allows a radiation detector carried by the robot to be moved in arbitrary paths around a patient in order to generate multiple projection exposures of the relevant region of the patient during the procedure. The imaging system is used to generate two dimensional image data during movement of the catheter and prosthetic heart valve into place and to generate three dimensional image data of the prosthetic heart valve within the patient's heart. The two dimensional image data and the three dimensional image data are registered and superimposed for use in positioning of the prosthetic heart valve. Additional imaging may be performed once the prosthetic heart valve is in position.
US08252046B2 Drug-delivery endovascular stent and method for treating restenosis
An intravascular stent and method for inhibiting restenosis, following vascular injury, is disclosed. The stent has an expandable, linked-filament body and a drug-release coating formed on the stent-body filaments, for contacting the vessel injury site when the stent is placed in-situ in an expanded condition. The coating releases, for a period of at least 4 weeks, a restenosis-inhibiting amount of the macrocyclic triene immunosuppressive compound everolimus. The stent, when used to treat a vascular injury, gives good protection against clinical restenosis, even when the extent of vascular injury involves vessel overstretching by more than 30% diameter. Also disclosed is a stent having a drug-release coating composed of (i) 10 and 60 weight percent poly-dl-lactide polymer substrate and (ii) 40-90 weight percent of an anti-restenosis compound, and a polymer undercoat having a thickness of between 1-5 microns.
US08252045B2 Drug delivery from electroactive molecularly imprinted polymer
A device delivers a chemical or biological agent, the device comprises an imprint molecule (IM) to be delivered by the device; an electroactive molecularly imprinted polymer (EMIP) imprinted with the imprint molecule, the EMIP having a plurality of binding sites capable of binding the imprint; and an electric potential producing member (EPM), the EPM being capable of producing an electric potential between the EPM and the EMIP; whereby when the EMIP has a predetermined density of imprint molecule bound at the binding sites, and whereby when a sufficient potential is produced between the EPM and the EMIP, the imprint molecule is released from the binding site and thereby delivered by the device.
US08252043B2 Removable covering for implantable frame projections
The disclosure relates to medical devices for implantation in a body vessel, and methods of using and making the same. A medical device can include a frame with one or more projections each having at least one edge extending from the surface of the frame, and a biocompatible, water-soluble removable material coated over at least a portion of the at least one edge. The projections can be barbs positioned to engage the interior wall of a body vessel or to attach a material, such as a valve leaflet or graft, to the frame. The removable material can be dissolved within a body vessel upon implantation, thereby exposing the at least one edge. Methods of making an implantable medical device and methods of treating a subject are also disclosed.
US08252040B2 Aneurysm treatment device and method of use
The present application discloses an apparatus for treating vascular aneurysms and includes a radially expandable substantially cylindrical structure formed from a plurality of support members and defining a plurality of openings, and at least one reactive material strand selectively integrated into the substantially cylindrical structure. The reactive material is configured to assume a non-reacted state and a reacted state. The reactive material in the reacted state is configured to restrict a flow of blood to an aneurysm.
US08252039B2 Aortic root dissection treatment
A stent is provided for external application to an artery in which an aneurysm has occurred or is about to occur to provide support thereto, the stent being of bespoke character by virtue of its creation to conform morphologically to the actual contour of the artery captured using for example MRI, CAD and RP.
US08252036B2 Sealable endovascular implants and methods for their use
The present invention is directed towards sealable and repositionable endovascular implant grafts, and methods for their use for the treatment of aortic aneurysms and other structural vascular defects. Sealable, repositionable endograft systems for placement in a blood vessel are disclosed, in which endograft implants with circumferential sealable collars and variable sealing devices upon deployment achieve a desired controllable seal between the collar and the vessel's inner wall. Embodiments of endovascular implants according to the present invention may further be provided with retractable retention tines or other retention devices allowing an implant to be repositioned before final deployment. An endograft system according to the present invention further comprises a delivery catheter to allow placement through a peripheral arteriotomy site, and of sufficient length to allow advancement into the thoracic or abdominal aorta.
US08252035B2 Device delivery system with two stage withdrawal
A medical device delivery system provides for a two-stage withdrawal of a deflated balloon portion of a catheter and the remains of a ruptured sheath. The deflated balloon portion is withdrawn from within an expanded medical device a predetermined distance before the remains of the ruptured sheath begins being removed from between the expanded device and a vessel wall. Initiating removal of the deflated balloon portion before the sheath reduces a total amount of drag that is exerted against a self-expanding medical device that has been deployed in a vessel.
US08252033B2 Phototherapy apparatus for skin treatment
A wearable hands-free apparatus for providing phototherapy treatment to a number of skin related conditions includes a head unit (e.g., a headset, headphones, headband, or helmet unit) with earphones to allow the user to listen to an audio program during a treatment. The head unit supports a light emitting canopy band that is fitted with an array of light generating sources, such as light emitting diodes (LEDs), laser diodes, or infrared lights, that emit light within a particular wavelength range correlating with the treatment of one or more specific skin-related conditions. The light emitting canopy band is specifically designed for providing complete, uniform and consistent light coverage to a user's face.
US08252032B2 Bone plate with complex, adjacent holes joined by a relief-space
A bone plate is described which is adapted for use in situ to fix a spatial relationship of at least two bone parts. The bone plate has at least one pair of the bone screw apertures that are adjoined by a relief-space contiguous with the open space of the screw apertures themselves. An adjoined aperture pair forms a complex aperture and has a center-to-center distance of the apertures along an axis running through the centers of the apertures. The center-to-center distance is equal to or greater than the sum of the radii of the heads of the individual bone screw used with the aperture pair. At least one of the screw apertures has a screw head seat having at least one relief notch set into a surface of the screw head seat. The relief notch provides desirable advantages that are not similarly accomplished in their absence.
US08252031B2 Molding device for an expandable interspinous process implant
A molding device is disclosed and can include a first mold component and a second mold component substantially opposite the first mold component. The first mold component and the second mold component can fit around a superior spinous process and an inferior spinous process.
US08252026B2 Spinal implant for facet joint
An apparatus (10) and method are provided for supporting an adjacent pair of vertebra (14, 16) relative to each other by anchoring a support frame (30) to the superior spinous process (24) and the inferior spinous process (28) of two adjacent vertebra (14, 16); and anchoring the support frame (30) to either the superior facets (34) or inferior facets (32) of the two adjacent vertebrae (14, 16).
US08252023B2 Pacifier
Improved pacifiers are provided. Certain embodiments better accommodate the anatomy of the human oral cavity and throat, and can provide for improved airway patency, healthy jaw development, correct swallowing, and/or satisfy a user's inclination to suck and nibble. Certain embodiments include an upper ridge groove configured to receive a user's upper anterior ridge, and a lower ridge groove configured to receive the user's lower anterior ridge. The ridge grooves can be substantially vertically aligned, can span a user's anterior ridges, and can maintain vertical spacing between the user's anterior ridges. Certain embodiments include an anterior flange and a posterior flange, the upper ridge groove configured to receive the upper anterior ridge between the posterior flange and anterior flange, and the lower ridge groove configured to receive the lower anterior ridge between the posterior flange and anterior flange. Certain embodiments include a nipple projecting substantially vertically from the posterior flange.
US08252022B2 Metal vascular aperture closure device
A closure device to be inserted at least partially through a blood vessel wall aperture in a blood vessel wall. The closure device includes at least two parts, an internal part and an external part. The internal part is adapted to be extended at least partially through the blood vessel wall aperture and into the lumen to at least partially block the blood vessel wall aperture. Each of the internal part and the external part consists essentially of a metal that biodegrades within a living being in a period of time that permits biological repair of the blood vessel wall in and around the blood vessel aperture.
US08252019B2 Filter retrieval catheter system, and methods
A filter retrieval system for retrieving a previously implanted medical filter, and methods of using the retrieval system, are disclosed. The filter retrieval system has a flexible shaft, a retrieval element, and a handle with an actuator. The flexible shaft may be catheter-based, and has a proximal and a distal end, and has an opening near its distal end. The handle is affixed to the shaft near the proximal end of the shaft, and the actuator is adapted to manipulate the retrieval element. When an operator manipulates the actuator, the retrieval element is adapted to protrude slightly from the shaft opening. As the actuator is operated, the retrieval element can grasp or hook or otherwise engage a portion of the filter, and then pull the filter in through the opening into a passage or lumen of the catheter shaft. The retrieval system is capable of retrieving a filter in into a proximal and distal space defined by the flexible shaft, though only one space at a time.
US08252017B2 Invertible filter for embolic protection
A medical device including a guiding member and a filter portion is disclosed. The guiding member includes a lumen configured to slidably engage the filter portion. The filter portion forms a tubular geometry that extends distally from the guiding member. The filter portion is configured to evert to form a proximally facing concave geometry for capturing emboli. Further, the filter portion includes filter openings that are sized to allow blood cells to pass therethrough while preventing the passage of emboli.
US08252016B2 System and method for providing embolic protection
An apparatus for offering embolic protection is provided that includes a sponge operable to be positioned in an area of a patient who is to undergo a cardiovascular procedure. The sponge is operable to collect debris present in or proximate to the area and to allow a portion of blood flow or no blood flow associated with the area to continue while the debris is collected.
US08252012B2 Ultrasonic surgical instrument with modulator
A surgical instrument includes a transducer configured to produce vibrations along a longitudinal axis at a predetermined frequency. An end effector is adapted to couple to the transducer and extends along the longitudinal axis. The end effector includes a body having a proximal end and a distal end. The distal end is movable relative to the longitudinal axis by the vibrations produced by the transducer. A drive module is coupled to the transducer to generate a modulated drive signal. The distal end of the end effector is movable in response to the vibrations produced by the transducer in response to the modulated drive signal.
US08252010B1 Thrombectomy removal method
A method for removing a clot using and inserting a catheter balloon assembly, having proximal and distal ends including a catheter carrying a remotely inflatable occlusion balloon and another catheter carrying a mechanical device for moving a clot, into patient on one side of clot; a balloon-collared sheath, having a collar sheath with proximal and distal ends, the collar sheath having an open interior, and sealing valve for sealing the interior of the collar sheath, and inflatable collar balloon, disposed on the exterior distal end of said collar sheath, inserted on other side of clot; a suction module, having a suction sheath having proximal and distal ends, the suction sheath having an open interior, and sized to be inserted in a vein, attachable to a suction device. The balloons are inflated and the mechanical device is positioned near the clot, toward the balloon collared sheath towards the suction device.
US08252008B2 Articulating suturing device and method
Devices, systems, and methods for suturing of body lumens allow the suturing of vascular puncture sites located at the distal end of a percutaneous tissue tract. An elongated articulated foot of the device can be inserted through the penetration and actuated so that the foot extends along the lumenal axis. The foot can carry suturing attachment cuffs with one end of the cuff adapted to receive a needle, while the other end receives suture. A portion of the foot and/or lumen of the shaft can receive a portion of the suture and can include friction reducing structure that aid with movement of the sutured during removal of the cuffs from within the penetration.
US08252007B2 Suturing device, system, and method
Improved medical suturing devices, systems, and methods may hold a suture needle at a fixed location relative to a handle of the device, allowing the surgeon to grasp and manipulate the handle of the suturing device to insert the needle through tissues in a manner analogous to use of a standard needle gripper. Cycling the handle from a closed position to an open position and back to the closed position may alternate the device between gripping the needle with a first clamp (for example, along a proximal portion of the needle) to gripping the needle with a second clamp (for example, along a distal portion of the needle) and optionally back to gripping with the first clamp, with the needle often staying at a substantially fixed location relative to the suturing device body. Related single-clamp needle grasping devices can be bent plastically by a surgeon, and/or have bodies that are grasped by a hand while a portion of the hand actuates a handle.
US08252000B2 Femoral condyle cutting and shaping device
A femoral condyle cutting and shaping device includes a first bone shaping and cutting tool and at least one assistant shaft which are mounted in a sliding gearbox; at least one driven shaft mounted in a sliding gearbox; a first connecting member and a second connecting member, with one end of the first connecting member joining with one end of the second connecting member so as to form a hinge fitting; at least one other bone shaping and cutting tool mounted on the relevant driven shaft; an adjusting mechanism, which is connected with one driven shaft to change the relative position between the first bone shaping and cutting tool and the at least one other bone shaping and cutting tool. A bone shaping and cutting tool is also disclosed, which has flat or helical structure.
US08251998B2 Chondral defect repair
A tissue repair device. The tissue repair device includes a tubular shaft having a longitudinal bore for delivering biological material to a soft tissue defect, and an awl having a distal end configured for microfracturing bone underlying the defect. The tubular shaft and the awl are movable relative to one another such that the awl is at least partially positioned within the longitudinal bore of the tubular shaft.
US08251996B2 Insulating sheath for electrosurgical forceps
An electrosurgical forceps includes a shaft having a pair of jaw members at a distal end movable about a pivot from a first position disposed in spaced relation relative to one another to a second position wherein the jaw members are closer to one another for grasping tissue. One or both of the jaw members are adapted to connect to a source of electrical energy such that the jaw members are capable of conducting electrical energy to tissue held therebetween. An insulative sheath is fitted for removal atop at least a portion of an exterior surface of one or both jaw members, about the pivot and the distal end of the shaft. The insulative sheath houses a silicone lube configured to facilitate insertion of the forceps through a cannula after removal of the insulative sheath.
US08251995B2 Articulating ionizable gas coagulator
A method for coagulating tissue is disclosed. The method includes the steps of providing an electrosurgical apparatus including: an elongated flexible tube having a proximal end and a distal end and defining a longitudinal axis and at least one electrode mounted proximate to the tube for ionizing pressurized ionizable gas. The method also includes the steps of moving the distal end of the tube from a first position wherein the distal end is disposed in a generally parallel fashion relative to the tissue to a second position wherein the distal end directs pressurized ionizable gas flowing through the tube at an angle α with respect to the longitudinal axis and igniting the pressurized ionized gas through the at least one electrode.
US08251994B2 Vessel sealer and divider with blade deployment alarm
An electrosurgical forceps includes a selectively advanceable knife and a knife deployment alarm configured to emit a signal under predetermined conditions. An alarm is configured to emit a signal when the cutting blade moves relative to the blade channel. A series of resistances are arranged so that a shorting of each resistor is indicative of a predetermined operating condition triggering the alarm to emit a signal. Pressure sensors, optical measurement devices, and electrical contacts are envisioned for determining blade or trigger actuation or translation.
US08251990B2 Apparatus and method of performing radiofrequency cauterization and tissue removal
An apparatus for cauterizing and severing tissue from a patient's body is provided. The apparatus includes a sheath and a cauterization device. The sheath is adapted for insertion into the body. The sheath has a tubular cross-section and includes longitudinally spaced proximal and distal ends. The cauterization device includes a main body portion and a plurality of electrodes for contacting and cauterizing the tissue. Each electrode has longitudinally spaced proximal and distal ends and extends longitudinally through the sheath. The distal end of each electrode is adapted to selectively protrude from the distal end of the sheath to contact and cauterize the tissue. At least one of the plurality of electrodes includes at least one cutting edge formed adjacent the distal end for severing cauterized tissue from the body upon rotation of the main body portion.
US08251986B2 Method of destroying tissue cells by eletroporation
An apparatus and method for performing non-invasive treatment of the human face and body by electroporation in lieu of cosmetic surgery is provided. The apparatus comprises a high voltage pulse generator and an applicator having two or more electrodes in close mechanical and electrical contact with the patient's skin for applying the pulses to the patient's skin. The applicator may consist of two pieces with one electrode having a sharp tip and another having a flat surface. High voltage pulses delivered to the electrodes create at the tip of the sharp electrode an electric field high enough to cause death of relatively large subcutaneous fat cells by electroporation. Moving the electrode tip along the skin creates a line of necrotic subcutaneous fat cells, which later are metabolized by the body. Multiple applications of the electrode along predetermined lines on the face or neck create shrinkage of the skin and the subcutaneous fat volume underlying the treated area.
US08251983B2 Laser tissue fusion of septal membranes
A laser tissue fusion device is optimized for particular surgical applications to join tissue layers. The device has two opposed arms that engage and disengage to clamp and release layers of tissue therebetween. The distal end of the first arm is disposed opposite the distal end of the second arm. A laser energy source generates therapeutic laser energy is either integrated within the device is a separate unit. An energy pathway transmits the laser energy to the distal end of the first arm to deliver the laser energy to tissue layers clamped between the distal ends of the arms. An actuator decreases the separation distance between the distal ends of the arms to clamp the tissue layers and activates the laser energy source upon engagement. The laser energy source delivers a burst of energy at a predetermined wavelength for a predetermined period of time sufficient to spot weld the tissue.
US08251979B2 Orientation independent canister for a negative pressure wound therapy device
A portable negative pressure wound therapy system includes a dressing assembly for positioning over a wound to apply a negative pressure to the wound and a canister assembly. The canister assembly includes a control unit having a vacuum source and a controller and a collection canister in communication with the dressing assembly operable to receive fluid from the wound. The collection canister has a filter assembly having a filter and a passageway between the filter and a wall of the collection canister. The collection canister also includes a canister interface having a suction port, an inlet port, and a channel. The vacuum source draws air through the suction port from the channel which draws air from the passageway connected to the channel, the air in the passageway is drawn from the collection canister through the filter, and the air in the collection canister is drawn through the inlet port.
US08251978B2 Catheter with associated extension lumen
An intra-luminal device for the extraction of occlusive or partially occlusive material is disclosed. The device includes a novel catheter extension which minimizes cavitation of extracted fluids and also allows the better navigation of tortuous lumens or vasculature.
US08251976B2 Medical device incorporating a polymer blend
A catheter including a catheter shaft formed from a polymer blend and/or a braid. The polymer blend may include polyoxymethylene added in the dispersion phase to a polymer blend. The catheter braid can be formed from at least two continuous wires that are woven together. The catheter braid can include a proximal braid section and a distal braid section. Each of the continuous wires has a proximal diameter corresponding to the proximal braid section and a distal diameter corresponding to the distal braid section. The distal diameter of each wire can be less than the proximal diameter of that wire. A catheter braid so formed can be included in a catheter.
US08251975B2 Catheter and tunneling device therefor
A catheter for introduction and removal of fluids from a body and tunneling device therefor, the catheter has a body having a first conduit for removing fluid from the body and a second conduit for delivering fluid to the body wherein at least a part of each of the conduits is integrally formed within a first end of the body of the catheter and extends along side one another. The first conduit extends beyond the second conduit and forms a terminal point of the first end and defines a first opening thereat and the second conduit extends to a point short of the terminal point defining a second opening. A bumper portion is adjacent the second opening extending toward the terminal point. Another part of each the first and the second conduits are disjoined and form part of a second Y-shaped end. The tunneling device has a channel to removably receive the catheter.
US08251973B2 Medical devices and methods for assisting in sub-scab access
Device and methods for separating a scab from a vascular access site are disclosed. The devices include providing a scab separation device having a point for initial separation of a portion of a scab from a patient's flesh, and a series of inclined surfaces leading from the point to lift and separate the scab from the access site. The scab separation device is provided with a cover so that the device is maintained as sterile. In a preferred embodiment, the scab separation device is provided as a set or assembly with a needle or needle set and, in a more preferred embodiment, the scab separation device cover is also used as a cover for a needle to maintain sterility both of an operative end of the separation device and of the needle.
US08251967B2 Absorbing disposable incontinence diaper
A diaper having a main part comprising a front area, a rear area and a crotch area therebetween, wherein the main part comprises an absorbent core, and with rear side sections joined on both sides to the rear area and front side sections joined on both sides to the front area which extend in the transverse direction past lateral front and rear longitudinal edges of the main part, connect the front area and the rear area, wherein, at least on the side facing the crotch area, the front and rear side sections; are designed in such a fashion that they extend at an inclination with respect to the longitudinal direction or are curved for forming leg opening areas, and the front and rear side sections of the front area and rear area differ from each other with respect to at least one primary property.
US08251966B2 Absorptive article
Provided is an absorptive article having absorption elements capable of following the body of a user. This absorptive article (1) comprises a generally rectangular base absorption element (2), a top absorption element (3) disposed on one surface of the base absorption element (2) at substantially lateral center of the base absorption element (2) and along the longitudinal direction of the base absorption element (2), and a fixing part (4) for fixing the base absorption element (2) to the top absorption element (3) so that at least one end of the top absorption element (3) in the longitudinal direction thereof is made to be a free end (31). A temporary locking part (5) for restricting the movement of the top absorption element (3) is provided on the top absorption element (3) near a free end part (32) thereof at least before application of the absorptive article to the body of the user.
US08251964B1 Sanitary device and method
The present invention provides a sanitary device having a significant capacity (e.g. 30 c.c.) in an plastic pouch (or envelope) gently attached to the end of the male member by releasable pressure sensitive adhesive across an opening which receives the male member. The pressure sensitive adhesive provides close connection to the skin, provides a fluid closure around the male member, and permits closure with opposing adhesive surfaces of the sanitary device not used to surround the circumference of the inserted male member. A further feature provides flaps, tabs or margins at the sanitary device opening which are foldable over the adhesive to selectably cover some portion or all of the adhesive as may be desired by the wearer.
US08251963B2 Flexible needle
An endoscopic instrument comprises a first flexible insertion member sized for insertion through a body lumen to a target site and a needle coupled to the insertion member for penetration of tissue, the needle including a plurality of flexibility enhancing grooves formed therein along at least a first portion of the length of the needle.
US08251960B2 Valves, valved fluid transfer devices and ambulatory infusion devices including the same
Valves, valved fluid transfer devices and ambulatory infusion devices including the same. The valves includes a valve element and a valve seat, and one of the valve seat and the valve element includes a main portion and a seal portion that is less tacky than the main portion.
US08251959B2 Leaf spring valve and cone membrane valve
A delivery device and a method for administering a fluid from a fluid reservoir, wherein an unintended free flow of the fluid from the reservoir to a recipient is reliably prevented, are disclosed. The delivery device has a tank for the fluid; a fluid delivery device which delivers the fluid from the tank; a valve body providing an input hole and an output hole; and an infusion set in order to guide the fluid from the tank to a distal end of the delivery device. The delivery device further provides a shutter assembly which is or can be mounted to the valve body and prevents the fluid from flowing inside the infusion set when the fluid exhibits a pressure which is lower than a predefined pressure.
US08251952B2 Airless intravenous bag
The present disclosure provides for an airless intravenous (IV) bag which contains a specialized device, referred to herein as the airless intravasculature infusion device (AIVID). The AIVID allows one to view the amount of fluid in the IV bag but substantially decreases or completely prohibits the risk of an inadvertent air infusion into a patient.
US08251949B2 Balloon catheter with radiopaque marker
A catheter for delivering a stent includes an outer tube having a proximal end, a distal end and a wall defining a lumen; an inner tube disposed within the outer tube and defining a lumen for a guidewire, wherein a portion of a length of the inner tube is wrapped around with a spiral-shaped wire; a balloon sealingly connected to the inner tube and the outer tube adjacent the distal ends thereof, the balloon defining an interior volume and having an exterior surface; and a marker made from a wire of a highly radiopaque and ductile material, wherein the wire is wrapped in a plurality of at least partially overlapping layers such that the marker is flexible along the length of the catheter.
US08251948B2 Multi-function catheter and use thereof
A catheter for delivering an agent to an area of treatment is presented. The catheter includes a catheter body, a balloon assembly coupled to the catheter body, a first lumen, and a second lumen. The balloon assembly has spaced-apart balloons that define an area between the balloons. The first lumen extends along the catheter body to pass an inflation material to the balloons to control an inflation level of the balloons. The second lumen extends along the catheter body and having an outlet in the area between the balloons. There may be a third lumen for bypassing a biological fluid such as blood while the catheter is being used. The method of using this catheter is also presented. The method entails simultaneously inflating the balloons to isolate a treatment area and adding an agent to the treatment area through one of the lumens.
US08251945B2 Endoscopic suction device
A device for suctioning material out of an instrument channel during an endoscopic procedure. The device includes a biopsy valve having a first end, a second end, and an outer circumferential surface. The biopsy valve defines an internal passage leading from the first end to the second end, wherein the first end is adapted for connection to an endoscope instrument channel inlet port. Tubing connects the biopsy valve second end to a suction source connector disposed remote from the biopsy valve. A flow controller is fixed to the tubing and disposed between the biopsy valve second end and the suction source connector. The device may include an irrigation port and an instrument entry port.
US08251944B2 Surgical system having a cassette with an acoustic coupling
A surgical cassette have a rigid fluid channel formed into a rigid plastic component or housing. The housing serves as a substrate for an elastomeric acoustic coupling that can be formed on the housing outside of the fluid channel by an over molding process. Such a construction method eliminates the need for adhesives to attach the elastomeric acoustic coupling to the housing and ensures the removal of any air from between the elastomeric acoustic coupling and the housing.
US08251942B1 System and method for removing blood containing contrast dye
The system for removing blood containing contrast dye includes an inner catheter having a fixed proximal end and a distal free end, and an outer catheter coaxially disposed around a portion of the inner catheter, defining an inner channel and an annular outer channel. The fixed end of the inner catheter is coincident with the proximal end of the outer catheter, and the distal end of the inner catheter extends outward from the outer catheter. An annular suction orifice is defined between the distal end of the outer catheter and the inner catheter. First and second balloons are mounted adjacent the distal ends of the outer and inner catheters. The distal free end of the inner catheter extends beyond the second balloon. In use, the first and second balloons are inflated in the coronary sinus and blood containing contrast dye is then removed from between the first and second balloons.
US08251939B2 Cervical traction/stretch device and method for its use
A cervical traction/stretch system includes a traction/stretch mechanism for applying tension between a body's head and shoulders, the traction/stretch mechanism including a bellows; a pump operatively coupled with the traction/stretch mechanism for alternately inflating and deflating the bellows; and an at least semi-automatic controller operatively coupled with the pump for at least semi-automatically controlling the pump by activating and deactivating the same in such manner as to alternately and repeatably inflate and deflate the bellows to prescribed pressure levels over prescribed pressure intervals.
US08251938B1 Providing relative translation without rotation
A device may include a first plate and a second plate, and a linkage system that attaches the first plate and the second plate to one another such that the plates are capable of translating relative to each other, and the plates are incapable of rotating relative to each other.
US08251935B2 Ankle orthosis
The present invention provides an orthosis for stretching tissue around a joint of a patient between first and second relatively pivotable body portions. The orthosis includes a first member affixable to the first body portion and including a first extension member defining an arcuate channel therein. A second member affixable to the second body portion is also included and has a second extension member having an arcuate shape extending there from. The second extension member is operatively connected to the first extension member and travels through and within the arcuate channel, along the arcuate path, when the second arm member is moved from a first position to a second position relative to the first member.
US08251933B2 Compression-garment band method
A therapeutic compression garment is disclosed. The compression garment may include a first band wrapping around a first portion of a limb. The first band may deliver to the first portion a first level of therapeutic compression. The compression garment may further include a second band connected to the first band and positioned adjacent thereto. The second band may wrap around a second portion of the limb. The width of the second band may be greater than the width of the first band. Accordingly, when the first and second bands are applied with equal tension, the level of therapeutic compression provided by the second band may be less than the level of therapeutic compression provided by the first band.
US08251929B2 Integrated ultrasound therapy transducer assembly
The present invention is to provide an integrated ultrasound therapy transducer. It includes a piezoelectric transducer to generate therapy ultrasound, a support to support the piezoelectric transducer, a power amplifying module to drive the piezoelectric transducer. Wherein both the power amplifying module and the piezoelectric transducer are installed within the enclosure of the therapy transducer. The advantages of the integrated ultrasound therapy transducer assembly of the present invention include minimizing ultrasound therapy equipment and to decrease its volume and weight; reducing the electromagnetic interference and radiation greatly; and realizing the consistent performances of the ultrasound therapy equipments in mass productions and making the ultrasound therapy equipments have interchangeability.
US08251928B2 Method for carrying out a functional analysis of an artificial extremity
A method for carrying out a functional analysis on a person equipped with an artificial extremity having adjustable settings. The method includes the steps of providing a sensor assembly configured as a replacement for a part of the artificial extremity and installing the sensor assembly in place of the part. Forces, accelerations and/or torques are then measured with the sensor assembly during use of the artificial extremity by the person and the settings of the artificial extremity are optimized based on these measurements. The sensor assembly is removed and the replaced part is installed back into the artificial extremity, while retaining the optimized settings. In one embodiment, the artificial extremity is a leg prosthesis having an artificial knee joint with a rotational adaptor mounted above it. The sensor assembly then replaces the rotational adaptor.
US08251927B2 System and procedure for the analysis of the swallowing process in humans
Computer-implemented system (1) for the analysis of the swallowing process in humans, which comprises an exposure unit (2) of the individual's head and neck area to external stimuli (3); a data capture unit (4) of data from the response to external stimuli; a data digitization unit (5); a digitized data processing unit (6); a memory unit (7); a processed data display unit (8), with the digitization unit (5), the memory unit (7) and the data display unit (8) being controlled by a computer program, wherein the external stimuli (3) consist of electromagnetic radiation; and where the data from the response to the external stimuli (3) consist of a continuous data sequence, which can be temporally and/or spatially analyzed and parametrized. The invention also relates to a computer-implemented procedure for the analysis and quantification of the swallowing process in humans.
US08251921B2 Method and apparatus for body fluid sampling and analyte sensing
A method of controlling a penetrating member is provided. The method comprises providing a lancing device comprising a penetrating member driver having a position sensor and a processor that can determine the relative position and velocity of the penetrating member based on measuring relative position of the penetrating member with respect to time; providing a predetermined velocity control trajectory based on a model of the driver and a model of tissue to be contacted. In some embodiments, a feedforward control to maintain penetrating member velocity along said trajectory.
US08251920B2 Swing lance with integrated sensor
An apparatus for lancing skin and collecting a liquid sample. The apparatus having a housing with an outer periphery and a rotatable arm having a lance to puncture the skin. A sample collection area is attached to the arm. The arm of the apparatus rotates from a first position to a second position. As the arm rotates, the lance extends beyond the housing allowing the lance to contact the user's skin and create a lance site. As the arm continues to move to the second position, the lance is brought out of contact with the user's skin and back within the housing while the collection area is brought into position. When the arm is located in the second position, the collection area is in substantially the same location as the lance site on the user's skin.
US08251912B2 Method of assessing blood volume using photoelectric plethysmography
A method and system for assessing blood volume within a subject includes generating a cardiovascular waveform representing physiological characteristics of a subject and determining blood volume of the subject by analyzing the cardiovascular waveform. The step of analyzing includes generating a first trace of the per heart-beat maximums of the cardiovascular waveform, which is representative of the systolic pressure upon the cardiovascular signal, generating a second trace of the per heart-beat minimums of the cardiovascular waveform, which is representative of the diastolic pressure upon the cardiovascular signal, and comparing the respective first trace and the second trace to generate an estimate of relative blood volume within the subject. In accordance with an alternate method of analyzing harmonic analysis is applied to the cardiovascular waveform, extracting a frequency signal created by ventilation and applying the extracted frequency signal in determining blood volume of the subject.
US08251909B2 Acoustic imaging probe incorporating photoacoustic excitation
Embodiments of the present invention provide for a photoacoustic imaging probe for use in a photoacoustic imaging system, said probe comprising a cohesive composite acoustic lens incorporating aspheric geometry and exhibiting low or practically no measurable dispersion of acoustic waves constructed of at least one material with a low acoustic impedance and attenuation and a relatively low acoustic velocity and at least one other material with a low acoustic impedance and attenuation and a relatively high acoustic velocity is immersed in preferably a low acoustic velocity and low acoustic impedance fluid. The lens may be designed as a single cohesive composite telecentric lens, an acoustic zoom lens, or a catadioptric lens. The lens focuses acoustic waves on an acoustic imager which detects the image. The lens may be considered to be essentially monochromatic.
US08251908B2 Motion compensated image-guided focused ultrasound therapy system
An image-guide therapy system comprises a thermal treatment device (e.g., an ultrasound transducer) configured for transmitting a therapeutic energy beam, and The system further comprises an imaging device (e.g., a magnetic resonant imaging (MRI) device) configured for acquiring images of the target tissue mass and the thermal treatment device. The system further comprises a controller configured for controlling thermal dose properties of the thermal treatment device to focus the energy beam on a target tissue mass located in an internal body region of a patient, and a processor configured for tracking respective positions of the thermal treatment device and the target tissue mass in a common coordinate system based on the acquired images. The system may optionally comprise a display configured for displaying the acquired images.
US08251907B2 System and method for determining a treatment dose for a patient
In certain embodiments, a method of maintaining health of a patient uses an analyte detection system. The analyte detection system is coupled to the patient such that a bodily fluid of the patient is accessible to the analyte detection system. The method includes automatically initiating and conducting a measurement of an analyte in the bodily fluid using the analyte detection system. The method further includes determining a treatment dose for the patient based on the measurement using the analyte detection system.
US08251906B2 Signal processing for continuous analyte sensor
Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.
US08251903B2 Noninvasive physiological analysis using excitation-sensor modules and related devices and methods
Methods and apparatus for qualifying and quantifying excitation-dependent physiological information extracted from wearable sensors in the midst of interference from unwanted sources are provided. An organism is interrogated with at least one excitation energy, energy response signals from two or more distinct physiological regions are sensed, and these signals are processed to generate an extracted signal. The extracted signal is compared with a physiological model to qualify and/or quantify a physiological property. Additionally, important physiological information can be qualified and quantified by comparing the excitation wavelength-dependent response, measured via wearable sensors, with a physiological model.
US08251901B2 Retractor for minimally invasive surgery
A surgical retractor comprises an elongate member having a coupling region disposed at one end thereof. The retractor is adapted to engage a base of a head of a pedicle screw. The coupling region of the elongate member has a filament-receiving hole adapted to receive a filament which captures the head of the pedicle screw. During surgery, a physician may retract muscle and soft tissue by simply pressing the elongate member against such tissue.
US08251900B2 Surgical access devices and methods providing seal movement in predefined paths
Various methods and devices are provided for allowing multiple surgical instruments to be inserted into sealing elements of a single surgical access device. The sealing elements can be movable along predefined pathways within the device to allow surgical instruments inserted through the sealing elements to be moved laterally, rotationally, angularly, and vertically relative to a central longitudinal axis of the device for ease of manipulation within a patient's body while maintaining insufflation.
US08251890B2 Endoscope insertion shape analysis system and biological observation system
An endoscope insertion shape analysis system of the present invention includes an insertion state acquisition unit that acquires coordinate values of a plurality of locations in an insertion portion of an endoscope inserted in an examinee, an insertion shape detection unit that detects at least some insertion shapes of the insertion portion inserted in the examinee based on the coordinate values at the plurality of locations, a coordinate plane setting unit that sets a plurality of coordinate planes according to the coordinate values and the insertion shapes at the plurality of predetermined locations, an insertion shape projecting unit that projects the insertion shapes onto the plurality of coordinate planes and an insertion shape judging unit that judges whether or not a predetermined shape exists in the insertion shapes projected onto the plurality of coordinate planes.
US08251888B2 Artificial gastric valve
An apparatus and method are disclosed for treating overweight and obese patients by applying a restrictive Artificial Gastric Valve (AGV) on part of the stomach. The apparatus includes a mechanism to control the opening of the AGV automatically on demand, dynamically and progressively. The controlled opening of the AGV inside the stomach controls and regulates the flow of food.
US08251886B2 Dual-pulsation bi-ventricular assist device
A ventricular assist device is disclosed which comprises a sac for wrapping around a portion of a heart, the sac having one or more inflatable chambers for compressing the heart when the chambers being inflated and a blood outlet made to an aorta, the blood outlet being the sole opening in the human blood path in the vicinity of heart, wherein during a systolic phase the inflatable chambers inflate while blood flows out of the aorta through the blood outlet, and during a diastolic phase the inflatable chambers deflate while blood flows into the aorta through the blood outlet.
US08251881B2 Method for making a seamless plastic motion discomfort receptacle
A plastic motion sickness receptacle is disclosed having a seamless perimeter defined by a tubular member folded at a first closed end, and an open end including means for closing the receptacle after use. The plastic tubular member comprises integrally formed walls that terminate in a base at said closed end with the edges of the walls cooperating to form a fluid-tight relationship. An outer surface of the receptacle may include indicia printed thereon including instructions for using the bag upon the occurrence of motion sickness.
US08251873B2 Method for activating a clutch
A method for actuating a continuously variable clutch such that the torque to be transmitted by the clutch is continuously adjusted either electromechanically via an electromotive drive, hydraulically via a pressure actuator, or electromagnetically via an electromagnetic actuator. The torque transmitted by the clutch is adjusted by utilizing a position-dependent clutch torque specification.
US08251868B2 Travel operation structure for work vehicle
A travel operation structure of a work vehicle, comprising a pair of left and right side brake pedals disposed on either the left or right of a steering wheel; a hydro static transmission for changing the speed of travel; and a stop operation pedal disposed on the other of the left and right of the steering wheel; wherein the corresponding left or right side brake is applied when one of the pair of left and right side brake pedals is depressed, and when both the left and right side brake pedals are depressed, both the left and right side brakes operate, and travel is stopped; and when the stop operation pedal is depressed, operating oil of the continuously variable speed change device is directed into an oil tank, and the continuously variable speed change device is switched to a neutral stop position for blocking transmission of power to the travel device.
US08251866B2 Method for starting the combustion engine during a load shift in parallel hybrid vehicles
A method for starting the internal combustion engine, in parallel hybrid vehicles, in which the internal combustion engine is started, during a shift under load in purely electric driving operation, by the electric machine.
US08251864B2 Control device for hybrid vehicle drive apparatus
A control device for hybrid vehicle drive apparatus which executes an internal-combustion-engine rotation control for rotating an engine output shaft under a circumstance where a consecutive travel distance LM involved in a motor drive running mode exceeds a given consecutive travel distance determining value L1. The rotation of the engine output shaft results in an effect of accelerating the lubrication of an engine. Once the engine output shaft is rotated, no component parts of the engine actually take the completely same attitudes at time before and after such rotation. This avoids the component parts of the engine from continuously remaining contact with each other in the same attitudes when encountered with running vibrations during the motor drive running mode, minimizing adverse affect on durability of the engine due to the running vibrations occurring in the motor drive running mode.
US08251863B2 Continuously variable transmission with multiple outputs
A transmission or actuator offering multiple rotational outputs proportionate in speed to that of a common rotational input, each output according to its own ratio. The ratios are continuously variable between positive and negative values, including zero, and may be varied by electromechanical actuators under computer control. The transmission relates the output speeds one to another under computer control, and thus makes possible the establishment of virtual surfaces and other haptic effects in a multidimensional workspace to which the transmission outputs are kinematically linked. An example of such a workspace is that of a robotic or prosthetic hand.
US08251862B2 Planetary carrier pinion pin retainer plate
A shaft retainer for a planet gear carrier of a planetary gear assembly both retains the pinion shafts within the carrier and maintains their angular orientation to achieve improved oil flow to the pinion bearings. Each of the pinion shafts includes an opening and an axial passageway that communicates with a radial passageway at the middle of the shaft. At the end of the pinion shaft opposite the axial passageway opening is a flat extending across the shaft. The flat is normal to the axis of the radial passageway. The pinion shafts are slip fit into suitable bores in the planetary gear carrier and support a needle bearing and planet or pinion gear. At one end of the carrier, the flats are engaged by a circular retainer so that the radial passageways of each of the pinion shafts are oriented radially outwardly. The circular retainer may either be a flat circular plate or have an L-shaped cross-section. The circular retainer may be affixed to the planetary gear carrier by a snap ring or a plurality of fasteners. At the end of the carrier having the axial shaft passageway openings, a lube dam directs a flow of lubricating oil from a source such as a hollow drive shaft to the open axial ends of the pinion shafts.
US08251861B2 Planetary wheel end with piloted sun gear shaft
A planetary wheel end assembly includes an axle shaft having an inboard end and an outboard end, a planetary gear assembly receiving driving input from the axle shaft, and a rotational support element that pilots the outboard end of the axle shaft. The planetary gear assembly includes a sun gear that is fixed for rotation with the axle shaft, a plurality of planet gears that are in meshing engagement with the sun gear, a non-rotating ring gear that is in meshing engagement with the planet gears, and a planetary spider that supports the plurality of planet gears. The planetary spider provides driving output to rotate a wheel component. The rotational support element is positioned radially between the outboard end of the axle shaft and planetary spider to allow relative rotation between the planetary spider and the outboard end of the axle shaft.
US08251860B2 Planetary gear set
A planetary gear set includes: a sun gear, a plurality of planetary gears externally meshed with the sun gear, and a carrier that interconnects the plurality of planetary gears such that the plurality of planetary gears revolve around a exterior circumference of the sun gear, and an arrangement of the plurality of planetary gears is rotationally non-symmetrical.
US08251854B2 Transmission apparatus
A transmission apparatus for transmitting power from a motor for driving an airport ground support tractor includes a torque converter for transmitting torque from the motor. A planetary gear train is structured such that in a first mode of operation, when an input shaft is rotated in a first rotational direction, a casing is rotated in the first rotational direction. However, in a second mode of operation, rotation of the casing relative to a housing is inhibited so that a support rotates in a second rotational direction. The arrangement is such that a driven end of a main shaft is secured to the support so that the support selectively drives the main shaft in the first rotational direction and the second rotational direction. An electro-hydraulic actuator selectively moves a synchro device between a first and second dispositions thereof for establishing a first and second gear ratios.
US08251852B2 Arrangement with at least one hydraulically bidirectional actuatable switching element
An arrangement with at least one shifting element (2) arranged within a housing (1) of a transmission which can be hydraulically acted upon with a pressure medium from a pressure medium supply for the purpose of being coupled to and decoupled from at least one component of the transmission. The pressure medium supply to the shifting element (2) is additionally used for the continuous supply of at least one of lubricant and coolant to at least one other structural element arranged within the housing (1) of the transmission.
US08251851B2 Remote oil pumping system for an automatic transmission
An auxiliary oil pumping system for an automatic transmission includes an auxiliary oil pump, the auxiliary oil pump being separate from an internal oil pump of the transmission but connected to an oil circuit of the automatic transmission to circulate oil in the system. An oil pump motor is connected to the auxiliary oil pump and selectively connectable to a power source for driving the auxiliary oil pump when a vehicle engine is off and the internal oil pump is not operating.
US08251848B2 Power split dual input shaft transmission for vehicle
A vehicle transmission includes at least two driving shafts to which power is transmitted from a power source, a driven shaft to which power is transmitted from the driving shafts, drive transmission mechanisms disposed between the driving shafts and the driven shaft, and a switching mechanism that selectively enables power transmission via the drive transmission mechanisms. The driving shafts are disposed concentrically and fitted rotatably relative to each other. The driving shafts are parallel to the driven shaft. A first drive unit is disposed coaxially with the driving shafts. A second drive unit is disposed coaxially with the driven shaft. The first and second drive units are interconnected so as to send and receive powers changed in energy form to and from each other. The transmission thus constructed is excellent in power transmission efficiency, quietness, vehicle mountability, etc., and can realize continuously variable speed change.
US08251844B2 Goalkeeper stick with angled shaft
A goalkeeper's hockey stick with an angled shaft is disclosed. The goalkeeper stick is comprised of a shaft, paddle and blade. The shaft connects to the paddle which connects to the blade. The portion of the shaft where it connects to the paddle is angled to the top portion of the paddle to provide a grip portion of the shaft where the goalkeeper's gloved hand can grip the stick in a way that the paddle and shaft can lay flat on the playing surface with no gap when the goalkeeper is in a defensive stance.
US08251843B1 Warning mat for pitching mound
A portable pitching mound having a base with a lower peripheral edge that is flush to the ground and an arcuate cross section to form a shell. A warning mat is attached to at least a portion of the base. Attached to the base and covering the warning mat is a layer of frictional material.
US08251840B2 Low lift golf ball
A golf ball formed from a single piece of material, the ball having an outer surface and a plurality of dimples formed on the outer surface, the outer surface being divided into plural areas, a first group of areas containing a plurality of first dimples and a second group of areas containing a plurality of second dimples, each area of the second group abutting one or more areas of the first group, the first and second groups of areas and dimple shapes and dimensions being configured such that the golf ball is spherically symmetrical as defined by the United States Golf Association (USGA) Symmetry Rules and such that the first and second groups of areas produce different aerodynamic effects, the first dimples being of different dimensions from the second dimples.
US08251836B2 Putter head with maximal moment of inertia
A putter head has a front that strikes a golf ball during putting, a length a, a width b, a weight W, and a moment of inertia I. The width extends along a horizontal width axis perpendicularly intersecting the front of the putter head. The length extends along a horizontal length axis perpendicularly intersecting the horizontal axis. The dimensions are, for example, a≦7 inches, b≦a, and I/Wa2>0.30.
US08251832B2 Method and system of positionable covers for water amusement parks
A water transportation system and method are described, generally related to water amusement attractions and rides. Further, the disclosure generally relates to water-powered rides and to a system and method in which participants may be actively involved in a water attraction. This transportation system may include a plurality of covers forming a covering system over at least a portion of the water transportation and/or amusement system. In some embodiments, at least one of the covers may be positionable. In addition, the water transportation system may include conveyor belt systems and water locks configured to convey participants from a first source of water to a second source of water which may or may not be at a different elevation.
US08251823B2 Video game processing apparatus, a method and a computer program product for processing a video game
Game information delivered from other video game processing apparatus different from a player's own video game processing apparatus is received via radio communication. Conditional read data and unconditional read data are stored in an information storage as the game information received by the information receiver. The conditional read data cannot be read when a specific condition is met, while the unconditional read data can be read unconditionally. It is determined whether or not the specific condition is met during progress of the video game. When the game information indicates the unconditional read data, the unconditional read data are set to readable in the case where the unconditional read data are stored in the information storage. On the other hand, when the game information indicates the conditional read data, the conditional read data are set to readable in the case where it is determined that the specific condition is met.
US08251816B2 Gaming system having controllable dynamic signage
A gaming system comprises a first gaming device displaying a first primary wagering game in response to receipt of a first wager from a first player and a second gaming device displaying a second primary wagering game in response to receipt of a second wager from a second player. The system further comprises a community display having a plurality of display regions thereon, and at least one controller operative to (i) detect activation of a first supplemental feature by the first player, (ii) detect activation of a second supplemental feature by the second player, (iii) determine in which of the plurality of display regions to display the first and second supplemental features in accordance with at least a first rule set, and (iv) display the first and second supplemental features on the community display.
US08251814B2 Gaming machine having light emitting device
A gaming machine includes a cabinet, an emission control unit, an exterior member, a conductive sheet, a ground unit, and a controller which runs a game. The emission control unit provided to the cabinet includes a light emitting portion and causes the light emitting portion to light. The exterior member is placed to a position surrounding the emission control unit and transmits light emitted by the light emitting portion to outside. The conductive sheet is provided to a position interposing between the exterior member and the emission control unit. The ground unit grounds the conductive sheet.
US08251809B2 Contactless card reading in a gaming machine
A gaming machine may be activated by an individual player for subsequent play by displaying to the gaming machine, without physical contact with the gaming machine, a card carried by the player. The card carries indicia which may include suitable electronic memory, to be sensed by apparatus associated with the gaming machine, to cause the wireless transfer of individualized data concerning the player from the card to the gaming machine or to a computer network that is associated with the gaming machine. The data is evaluated against a stored database, which database may include identification of the card holder. The data is then evaluated against the stored database, and the gaming machine is activated for subsequent play upon favorable evaluation of the data.
US08251804B2 Gaming system having progressive jackpots flexibly linked with common progressive pool
A linked progressive wagering system, comprises a first progressive wagering subsystem comprising X jackpots, each of the X jackpots displayed on a first meter. The system further comprises a second progressive wagering subsystem having Y jackpots, each of the Y jackpots displayed on a second meter. The system further comprises at least one wager input device, a progressive pool, and at least one controller. The at least one controller is operative to (i) receive a signal from the at least one wager input device of receipt of a first wager on the first progressive wagering subsystem, (ii) generate an increment, the increment comprising a portion of the first wager, (iii) transfer the increment into the progressive pool, (iv) add a first increase equal to the increment to the X jackpots, and (v) add a second increase equal to the increment to the Y jackpots.
US08251799B2 Gaming machine and method having a perceived skill component
Disclosed are a gaming machine and method including a perceived skill component comprising a skill-based award and a supplemental award that, when summed, are equal in value to a predetermined award.
US08251792B2 Peripheral device control system for wagering game systems
Methods and systems for assigning addresses to peripheral devices in wagering game machines are described herein. In one embodiment, a method includes transmitting a first request in a wagering game machine, wherein the first request is addressed to a configuration address, and wherein the wagering game machine is configured to present wagering games upon which monetary value can be wagered. The method can also include detecting a first response to the first request, the first response originating from a first of a plurality of peripheral devices of the wagering game machine. The method can also include assigning a first address to the first of the plurality of peripheral devices and notifying the first of the peripheral devices about the first address.
US08251791B2 Gaming system having multiple gaming machines which provide bonus awards
A gaming system including a central server linked to a plurality of gaming machines, gaming tables, hand held gaming devices and/or community gaming displays. The central server monitors wagers placed on any games played. Based at least in part on the wagers placed, the central server determines when one or more bonus events will occur and which players to provide any bonus awards.
US08251787B2 Separating unit for a combine harvester
A separating unit for a combine harvester and operating in accordance with a principle of axial flow, has a housing having at least one separating grate provided with openings, a rotatably supported separating rotor located in the housing, a cover having a closed jacket surface including, on a side facing the separating rotor, a plurality of guide elements disposed next to one another coaxially to a longitudinal axis of the separating rotor and extending in sections in a radial direction of the cover, and at least one ramp-shaped crop flow deflecting element extending axially parallel to the longitudinal axis of the separating rotor and arranged on the side of the jacket surface facing the separating rotor.
US08251781B2 Sander
A clamp device for a sander includes: a clamp body slidable on a plate between a clamping position and an unclamping position at which positions a clamp strip contacts with or is away from a side surface of the plate; a support shaft provided on the plate close to the clamp body; an operating member having a first and second ends and rotatably connected to the support shaft, the first end being a connecting end connected to the clamp body, and the second end being an operating end extending above the clamp body, so that the operating member is elastically deformable in an expanding and contracting directions between the connecting end and the operating end; and an engagement member provided on the plate opposite to the support shaft and engageable with the operating end of the operating member while an intermediate portion of the operating member is being compressed.
US08251779B2 Grinding device with cleaning assembly
An exemplary grinding device includes a fixed barrel, a rotatable barrel, a grinding plate, an actuator and a cleaning assembly. The fixed barrel defines a chamber and includes a number of inner sidewall substantially parallel to a central axis, each of which defines a holding groove for holding a workpiece. The rotatable barrel is received in the chamber and includes an outer side substantially parallel to the central axis and defines an installation groove. The grinding plate is installed in each of the installation grooves. The actuator is configured for driving the rotatable barrel to rotate and simultaneously move up and down in the first chamber, such that the grinding plates contact the workpieces and grind the workpieces. The cleaning assembly is situated under the fixed barrel for cleaning the workpieces.
US08251775B2 Mechanism and method for detecting the motion of a shaft
A shaft motion detection mechanism capable of detecting the displacement of a rotating body in a direction along a rotational axis and the rotation of the rotating body is disclosed. In one embodiment, the invention is a conditioner head capable of detecting the displacement of a polishing disk in a direction along a rotational axis and the rotation of the polishing disk. A shaft rotates around a rotational axis and a cylindrical shaft is attached to the shaft so that the shaft can be displaced along the rotational axis. A first plurality of projections are formed on the surface of the shaft so as to be aligned in a circumferential direction. A second projection is formed around the entire circumference on the surface of the shaft. Proximity sensors arranged around the rotational axis sense the first and second projections to detect displacement and rotation of the rotating body.
US08251773B2 Control system for a fluid/abrasive jet cutting arrangement
A control system for a high pressure cutting arrangement is disclosed. The cutting arrangement comprises a liquid stream and a slurry stream, the slurry comprising abrasive particles suspended in a fluid. The liquid stream and the slurry stream are both supplied under pressure of about 300 MPa to a cutting tool, with at least a portion of the supplied pressure being converted to kinetic energy in the cutting tool to produce a combined liquid and abrasive stream at high velocity. The cutting tool includes a combining chamber into which both the liquid and slurry streams are introduced, the pressure in an entry region of the combining chamber being determined by the pressure of the liquid stream. The control system acts to actuate or prevent flow of slurry in the slurry stream by activation or de-activation of an energizing means up-stream of the chamber. Pressure in the slurry stream is substantially equal to the pressure in the entry region of the combining chamber whether or not slurry is flowing.
US08251772B2 Method for forming a brassiere cup
A method for forming a brassiere cup includes the steps of: forming an inner cup member and an outer cup member of the brassiere cup, respectively; spraying or coating the predetermined joining surfaces of the inner and outer cup members with a glue; heating a film and, while the film is softened, attaching it to the glue-sprayed or glue-coated surfaces of the inner and outer cup members by vacuum suction; and assembling and sealing the inner and outer cup members and filling a filler in between the inner and outer cup members. The filler in the brassiere cup thus formed can comply with the breast shape of each user to achieve optimal shaping and supporting effects.
US08251769B2 Simulated eye assembly for use in toy
A simulated eye assembly is provided. The simulated eye includes a motor, a first ball, and a first slider-crank transmission mechanism. The transmission mechanism comprises a slider connected to the motor, and a first crankshaft connected to the first ball. The slider is driven by the motor to cause the first crankshaft to rotate, which further causes the first ball to rotate.
US08251763B1 Life jacket beacon
The beacon for increasing the visibility of a person floating in water. The beacon includes a flotation core constructed of a buoyant material, an outer cover and an attachment mechanism. The attachment mechanism allows the beacon to be attached to a user, user's clothing or life jacket worn by the user. The beacon floats in an essentially vertical position when the bottom end of the beacon is submerged in water.
US08251758B2 Electrical contact
An electrical contact having a conductor connecting portion and a contact portion at each end, respectively, includes contact leaves arranged side by side and connected together at common edges thereof via a resilient connecting portion; engaging grooves formed on the contact leaves, respectively, and extending toward the conductor connecting portion from a front end thereof; and a pair of beveled contact surfaces respectively formed on side edges of a pair of opposed inner surfaces of each engaging groove. The pair of beveled contact surfaces come into surface contact with a corresponding pair of beveled contact surfaces of the mating electrical contact when the engaging grooves of the electrical contact are engaged with corresponding engaging grooves of the mating electrical contact upon the electrical contact being connected to the mating electrical contact.
US08251750B2 Adapter apparatus
An adapter apparatus for connecting two connectors of the same type includes a receiving rack used to fasten two connectors, and a connection board attached to the receiving rack. A number of first gold fingers and a number of second gold fingers are formed on opposite ends of the connection board, to be electrically connected to the connectors, respectively.
US08251747B2 Electrical connector with improved grounding means
An electrical connector (100) includes an insulative housing (1) having a receiving cavity (10) including a first receiving cavity (12) and a second receiving cavity (13) communicating with the first receiving cavity; a set of first contacts (41) protruding into the first receiving cavity; a set of second contacts (42) exposed to the second receiving cavity; a metal shell (5) enclosing the insulative housing; and a grounding means (6) attached to the metal shell and oblique to a front face (112) of the insulative housing for abutting against a metal panel and having an opening. The opening includes a lower opening (601) with a pair of chamfers (603) on top thereof and an upper opening (602) communicating with the lower opening in a vertical direction and being essentially narrower than the lower opening (601).
US08251746B2 Shielded electrical connector
An electrical connector includes a shielding cage, an insulative housing disposed within the shielding cage, at least two rows of terminals secured in the insulative housing and a metal sheet embedded in the insulative housing and disposed between the rows of terminals. An insulative housing defines a mating face and a mounting face perpendicular to the mating face. The metal sheet extends from the mating face to the mounting face and comprises at least one tail extending beyond the mounting face.
US08251740B2 HDMI plug and cable assembly
A high-definition multimedia interface (HDMI) plug on an HDMI cable assembly includes an indicator light that is illuminated only when both ends of the cable are plugged into a video source and a video sink. Embodiments include an HDMI plug that comprises a connector body having a mating end configured for insertion into a mating HDMI receptacle and containing electrical pins configured according to HDMI specifications, the pins including a +5V Power pin, a Ground pin, and a Hot Plug Detect pin. The HDMI plug further comprises an indicator circuit that includes a light-emitting diode and a transistor switch in series with the light emitting-diode, wherein the light-emitting diode and transistor switch are coupled to the +5V Power pin, Ground pin, and Hot Plug Detect pin so that the light-emitting diode is activated only when both the +5V Power pin and Hot Plug Detect pin are energized.
US08251739B2 Method and apparatus for aligning and securing a cable strain relief
The present disclosure relates to a strain relief. In various embodiments, the strain relief includes a strain relief body and at least one alignment feature. The strain relief body is configured to provide support for connection of a cable and/or a wire lead of the cable to a frame. The alignment feature is configured to facilitate alignment of the strain relief relative to the frame. In various embodiments, provided are methods of manufacturing a sensor with a strain relief. The methods may include forming the strain relief about a cable and/or wire leads, wherein the strain relief comprises at least one alignment feature, aligning the alignment feature of the strain relief to a complementary alignment feature of a frame, engaging the complementary alignment feature of the frame with the alignment feature of the strain relief, and electrically coupling the cable and/or wire leads to a circuit.
US08251737B2 Terminal block for a cable connector
Terminal block for a cable connector including insulation displacement contact slots at both sides wherein at least a part of the insulation displacement contact slots at one side of the terminal block are paired either by a corresponding insulation displacement contact slot or by a punch support at the opposite side of the terminal block. The punch supports can be provided with a cylindrical curvature with a radius corresponding to the radius of a cable to be punched.
US08251735B2 Electrical connector assembly with high-density configuration
An electrical connector assembly (100), comprises: a housing (1) having a receiving room (11) therein communicated with an exterior along a longitudinal direction, and the housing comprising a first shield part (15) and second shield part (16) assembled with each other; two paralleled printed circuit boards (21, 22) received into the receiving room and positioned in the housing; a metallic holder (8) binding the first and second shield parts; and a latch mechanism assembled to an exterior surface of the housing and having a portion shielded by the metallic holder.
US08251734B2 Locking device for power feeding plug
A locking device that locks a power feeding plug to a power receiving connector, one of the power feeding plug and the power receiving connector including a hook, the other one of the power feeding plug and the power receiving connector including a catch, the locking device including a lock bar that is moved between a first lock position, at which it holds the hook on the catch and a first unlock position, at which it permits the hook to move away from the catch. A wire is moved between a second lock position, at which it is engaged with the lock bar and restricts movement of the lock bar to the first unlock position, and a second unlock position, at which it is disengaged from the lock bar and permits movement of the lock bar to the first unlock position. A motor is arranged at a position separated from the power receiving connector. A cam transmits the driving force of the motor to the wire.
US08251731B2 Electrical connection system and method for implantable medical devices
A multiple contact connector interfaces between an implanted medical device and an implanted cable or lead. A connector connects between multiple implanted leads, each of which has multiple independent conductors. The connection system is a planar array of male connector pins on one portion, and a matching array of female connector receptacles on a second portion. Alignment via alignment features and pressing together the portions allows pins to engage with the receptacles providing a secure electrical connection. Sealing features on the connector apparatus seal out external fluids and isolate fluid present in the connector apparatus prior to mating, which electrically isolates each pin and its corresponding receptacle from other pin and receptacle pairs. Latching features retains the relative position of the pins, receptacle, and the positioning of the fluid seals, and is reversible for removal of the connector.
US08251729B2 Universal frame for testing semiconductor device
A universal frame for connecting a semiconductor device to a test device, the universal frame including a connector for establishing a connection between the semiconductor device and the test device; a head part fixing a position of the connector; a body part fixing a position of the head part, the body part being configured to accommodate the semiconductor device; and a guide unit within the body part, the guide unit being configured to receive the semiconductor device at an end of the body part opposite to an end of the body part fixing the position of head part, and being configured to accommodate the semiconductor device
US08251725B2 Cylindrical electrical connector with floating insert
An electrical connector comprising: a conductive housing that contains within an interior of the housing a conductive inner barrel; a low insertion force connector positioned within the inner barrel and having a bore concentrically aligned with a bore of the inner barrel, the housing further comprising: one or more conductive springs disposed circumferentially about the inner barrel and in contact engagement with an interior recessed surface of the inner barrel and the interior of the housing so as to be in electrical contact therewith, wherein the bore of the inner barrel is adapted to receive a conductive pin, the inner barrel being movable both axially and radially via said spring in response to insertion of the conductive pin through the bore and into the low insertion force connector to accommodate off axis orientation of the conductive pin into the connector.
US08251722B2 Electrical connector and one pair of switch terminals thereof
An electrical connector includes a base, terminals each being disposed on the base and having a contact, and one pair of switch terminals, disposed on the base, including first and second terminals each having a fixing portion, a pin portion and an extension. The base has a connection slot for accommodating an electronic element. The first and second terminals have the fixing portions, each fixed to the base and having a plateless section. The extensions respectively have corresponding connection points. The extension of the first terminal has a pushing portion. The electronic element is inserted into the slot to push the pushing portion to make the extension of the first terminal be elastically moved to touch the switch terminals. Plate surfaces of the fixing portions are arranged in parallel or on the same plane and fixed to the base, and do not overlap with each other.
US08251720B2 Push-push card connector
A card connector for connecting an electronic card, comprises an insulative housing and an ejector. The insulative housing defines a receiving space extending backwardly along a front to back direction for receiving the electronic card. The ejector comprises a slider, a spring sandwiched between the slider and a rear end of the insulative housing and a pole for controlling movement of the slider. The slider includes a first protrusion and a second protrusion, the card connector has a first guiding groove engaging with the first protrusion and a second guiding groove engaging with the second protrusion, the slider defines a locking portion extending inwardly into the receiving space, the first guiding groove provides an escaping groove for the first protrusion thereby the slider can move along a insertion direction of the electronic card steadily.
US08251718B2 Power device with a movable connector plug
A power device includes a substrate portion and a connector plug. The substrate portion defines a recess portion and a pair of receiving grooves, and includes at least one contact terminal. The connector plug includes a main body and a pair of conducting strips protruding outwardly from the main body. The main body defines at least one receiving slot. The pair of conducting strips are received in the receiving grooves correspondingly and the contact terminals slide into the corresponding receiving slots to accommodate the connector plug in the substrate portion. The main body and the recess portion are in a square shape respectively, so that the connector plug is capable of turning for 90 degrees relative to the substrate portion to be mounted on the substrate portion.
US08251713B2 Contact terminal having insulative cap
An electrical connector includes an insulative housing and a plurality of contacts received in the housing. Each contact has a base portion, a resilient arm and a contacting portion located at one end of the resilient arm. The contacting portion has a free end attached with an insulative member so as to prevent short circuit with an adjacent contact.
US08251709B2 Electrical connector with improved cable fixation
An electrical connector includes a housing including a mating portion located in the front portion thereof, a plurality of contacts received in the housing and each including a tail extending out of the rear wall of the housing, a cover assembled on the housing, and a plurality of cables. The mating portion of the housing defines a mating direction and a rear wall. The cables each includes an inner conductor electrically connected to the tail of the contact, an inner insulation layer, an shielding braids and an outer insulation layer. The rear wall includes a plurality of ribs every two of which form a receiving slot therebetween and a plurality of protrusions every two of which form a fastening slot therebetween. The ribs and the protrusions respectively extend in two rows along a horizontal direction perpendicular to the mating direction and form a groove therebetween. The outer insulation layers of the cables are fastened in the receiving slots and the inner insulation layers are fastened in the fastening slots.
US08251706B2 Data cable with suction cup and electronic device using the same
An electronic device includes a main body and a data cable. The main body includes a number of exposed first conductive members. The data cable includes a first data port and a second data port. The first data port is capable of being connected to an external electronic device. The second data port includes a suction cup and a plurality of second conductive members mounted within the suction cup and electrically connected to the first data port. Each second conductive member corresponds to one first conductive member. When the first data port is electrically connected to the external electronic device, and the suction cup is adhered to the main body to cause each of the second conductive members to contact the corresponding first conductive member, the electronic device is capable of sharing data with the external electronic device.
US08251697B2 Reduced-friction buccal tube and method of use
An orthodontic appliance includes features for reducing friction between an interior of an archwire slot portion of the appliance and an archwire to be placed within the archwire slot. Other embodiments include a rounded exterior occlusal surface. Embodiments further include one or more receptacles for receiving an installation tool.
US08251694B2 Method for in-furnace reduction flue gas acidity
A method for of reducing the acidity and lowering the acid dewpoint of flue gas, the method steps including partially combusting the fuel in a first stage to create a reducing environment; maintaining the reducing environment for a sufficient time period such that reducible acids are reduced to achieve a desirable acidity concentration in the flue gas; and combusting the remainder of the fuel and combustion intermediates in a second stage with oxidizing environment; thereby decreasing the acidity and lowering the acid dewpoint of the flue gas by reducing the acid concentration of the gas.
US08251692B2 Sprue bushing for use in an injection mold
A sprue bushing includes a head, and a main body. The main body is connected to an end of the head. The main body defines at least one lateral channel. The at least one lateral channel extends through a sidewall of the main body. The sprue bushing defines a sprue and at least two longitudinal channels. The sprue extends through the head and the main body along a center axis of the sprue bushing. The at least two longitudinal channels extend through the head into the main body. One of the at least one lateral channel communicates with two of the at least two longitudinal channels.
US08251689B2 Ultraviolet light-emitting diode device
An ultraviolet (UV) light-emitting diode (LED) device for curing fluids such as inks, coatings, and adhesives, for example. In one embodiment, LEDs are positioned on faces defined by an inverted recess in a base portion. The LEDs are configured such that the light beams emitted from the LEDs converge at a single area or point to provide a single, focused area or point of amplified power from the LEDs. An optical culmination device may be used to further intensify the power output from the LEDs. The optical culmination device provides enhanced power output from the UV LED device which makes the curing process more efficient than previous curing systems.
US08251688B2 Apparatus for a mold vacuum system and method of forming a sheet utilizing the system
A method and an apparatus to form a sheet of polymeric material have first and second mold halves which clamp together on a polymeric sheet. A vacuum mechanism draws the sheet into an interior space. The vacuum mechanism has a plurality of controllable vacuum ports positioned about the interior space to direct the vacuum at specific portions of the sheet. Also, the sensing mechanism determines the draw depth of the sheet.
US08251680B2 Fan motor attaching structure
A fan case and a fan unit realize a fan motor attaching structure in which a fan motor is fixed without a tightening part while the number of functional parts is decreased. The fan case is formed in a box shape having an opening formed by a bottom face, side faces, a front face, and a rear face, and the opening is substantially similar to an outer shape of at least the two fan motors. The front face includes a handle, and the rear face has an opening to expose a connection surface of a connector electrically connected to the fan motor. The side face includes a first latch and a second latch, which are provided so as to be projected toward the opposite side face. A ventilating hole and a bent portion are provided in the bottom face.
US08251674B1 Brushless cooling fan
A fan assembly with impeller and shroud for application in a vehicle cooling system. The fan is powered by an external rotor brushless direct current (BLDC) motor having an electronic controller positioned away from the BLDC on an outer shroud wall with a plurality of ducts drawing an airflow from a static lower pressure created by the impeller, the airflow streaming over a heat sink disposed on the controller, exiting through a shroud. The static lower pressure air is pulled by a centrifugal fan and skewed magnets inside the motor through a plurality of ducts in a shroud hub, cooling the BLDC, maintaining low resistance for high efficiency. The BLDC is integrated into the assembly, having a stator fixed in the shroud hub and a rotor directly fused to the impeller, the shroud and impeller forming the BLDC motor without a housing, allowing the motor to easily dissipate heat.
US08251673B2 Displacement control valve of a variable displacement compressor
A displacement control valve of a variable displacement compressor opens and closes a communication passage extending between a portion of the compressor on which discharge pressure acts and a crank chamber of the compressor. The displacement of the compressor is controlled, such that discharge chamber pressure does not act on the valve body in the opening and closing direction, and pressures acting on the opposite ends of the valve body are maintained at the same level.
US08251670B2 Device and method for protecting aircraft component from collision with flying objects
A device for protecting an aircraft component from collision with a flying object, the device having: a main member rotating about an axis and subject to collision with a flying object; and diverting means connected angularly to the main member, also subject to collision with the flying object, and designed, in the event of collision of the main member with the flying object, to reduce the axial momentum of the flying object and divert the flying object radially with respect to the axis.
US08251667B2 Low stress circumferential dovetail attachment for rotor blades
A retaining system is provided for circumferential entry rotor dovetails inserted into dovetail slot in a rotor. A plurality of rotor blade dovetails are circumferentially slidable into and along the dovetail slot, with each rotor blade dovetail having a neck and a pair of oppositely oriented lobes. A plurality of rail segments are circumferentially slid into channels in the dovetail slot between the dovetail lobes and the respective disk hoops. The rail segments define a first pressure face that engages against an outward pressure face of the dovetail lobes, and a second pressure face that engages against an inward pressure face of the respective disk hoop component.
US08251666B2 Blade and fan having the same
A blade of a hybrid type fan includes: a blade body 21 made of a synthetic resin; and a metallic insert 22 that is insert molded simultaneously with the blade body 21 and mounted to a mounting arm of a spider. At a corner on an outer side of a radial direction and a forward side of a rotary direction of the insert 22, a bulging portion 26 is provided to bulge toward the outer side of the radial direction and the forward side of the rotary direction. A bulging region 27 of the bulging portion 26 that the most prominently bulges toward the outer side of the radial direction is located to be forward in the rotary direction relative to a mounting center C of the insert 22 and the mounting arm along the radial direction.
US08251665B2 Turbine blade and gas turbine equipped with a turbine blade
A turbine blade is presented including a vane that runs along a blade axis and a platform region, which is located at the root of the vane and has a platform that extends transversally to the blade axis. An improved cooling of a platform region and the transition region is provided from a turbine blade to a platform of a turbine blade. The platform includes a first platform wall that does not support the vane and a second platform wall that supports the vane. At the root of the vane and over the course of the transition region from the turbine blade to the platform, the first platform wall is aerodynamically curved and the course of the second platform wall has a receding shoulder in relation to the first platform wall, as a continuation of the vane.
US08251664B2 Fan blade for a gas-turbine engine
A fan blade for a gas-turbine engine which comprises a supporting structure (2) in fiber-composite material is enclosed by a sheet-metal enveloping structure (4) only in an area of the airfoil (3) such that the loads and stresses acting on the blade root (11), as well as the risk of delamination caused by the high bending load in the transition area between airfoil and blade root, are minimized.
US08251656B2 Actuation system for a wind turbine blade flap
Actuation system for a wind turbine blade flap.A method of actuating a flap (9) in a wind turbine rotor blade (1) is provided wherein a fluid is used for reversibly expanding an actuating element (16, 17, 19) acting a movable part (13) of the flap by varying the fluid pressure in the actuating element (16, 17, 19). Further, a wind turbine rotor with a rotor blade (1) comprising a flap (9) and a flap actuating system, where the flap comprises a fixed part (12) that is fixed to the rotor blade (1) and a movable part (13) that is movable relative to the fixed part (12), is disclosed, in which the flap actuating system comprises an actuating element (16, 17, 19) with a reversible changeable volume located between the movable part (13) of the flap and the fixed part (12) of the flap, a fluid within the actuating element (16, 17, 19) the pressure of which is settable and a pressure setting device which is designed to press fluid into or release fluid from the element (16, 17, 19) as to change its volume.
US08251655B2 Fan and frame with sensor-supporting structure thereof
A fan and a frame with a sensor-supporting structure are disclosed. The fan includes a frame with an inlet, a connecting portion disposed on the frame, a stator, and a rotor having blades and disposed in the frame. The frame includes a main body and a sensor-supporting structure. The sensor-supporting structure extending from the main body toward the inlet is utilized to support a sensor.
US08251649B2 Blade row of axial flow type compressor
In a blade row of an axial flow type compressor in which a rotor blade row and a stator blade row are alternately arranged in an axial direction, the stator blade row 10 is formed by plural main stator blades 12 and plural sub-stator blades 14. Each main stator blade 12 is formed by a basic blade portion 12a which has the same shape as that of each sub-stator blade and a forward blade portion 12b which extends to the upstream side of the basic blade portion. The basic blade portion 12a are located at the same position in an axial direction. The forward blade portion 12b forms a forward stator blade row which has a circumferential interval larger than that of the basic stator blade row in the vicinity of at least a radial inner end.
US08251648B2 Casing treatment for axial compressors in a hub area
A fluid flow machine includes a flow path formed by a casing 1 and a rotating shaft 2, in which rows of blades 3 are provided, with at least one annular groove-type recess 4 being arranged in a blade 3 tip area in an annulus duct wall of the shaft 2. A cross-section and the position of the recess 4 are defined as follows: the axial arrangement is selected such that a partial length A of the recess 4 extends by max. 30 percent of the chord length of a blade 3 from the blade 3 leading edge against the direction of flow, and up to max. 50 percent of the chord length of the blade 3 from the blade 3 leading edge in the direction of flow.
US08251645B2 Fan with concealed oscillating mechanism
A fan with concealed oscillating mechanism includes a main housing, a first driving motor, a second driving motor and a curved link gear all located inside the main housing, and a set of blades located outside the main housing and connected to a rotating shaft of the first driving motor. The first driving motor has a connecting rod rotatably received in a receiving tube provided in the main housing. The second driving motor is located behind and connected to the first driving motor, and has a rotating shaft being perpendicular to that of the first driving motor. The curved link gear is connected at an end to the second rotating shaft and at another end to the main housing, such that when the second driving motor operates, the first driving motor is brought to oscillate while the set of blades stably rotates to thereby change the direction of produced airflow.
US08251642B2 Centrifugal fan
A centrifugal fan includes a top cover plate, a bottom plate, a sidewall and an impeller. The sidewall is defined with an air outlet. The impeller includes a hub and a plurality of blades extending radially outwardly from the hub. An air passage channel is defined between outmost free ends of the blades and an inner surface of the sidewall. A tongue is provided near the air outlet and protrudes inwardly and laterally from the inner surface of the sidewall towards the outmost free ends of the blades. The tongue has an outer surface facing the outmost free ends of the blades. A plurality of grooves is defined in the outer surface along a lengthwise direction of the tongue.
US08251636B2 Lid closing method for closed container and lid opening/closing system for closed container
Provided is a method of detecting whether or not a lid is fixed to a pod appropriately when performing an operation of closing an opening of the pod by the lid in an FIMS system. Determination is made whether or not a door is present at a predetermined position when the lid is attached to the pod and whether or not the pod is displaced from a position of opening/closing the lid, and determination is made again, after the lid engages with the pod, whether or not the door is present at the predetermined position and whether or not the pod is displaced from the position of opening/closing the lid. When it is confirmed in both the determinations that the door is present at the predetermined position and the pod is not displaced, determination that fixation of the lid is appropriate is made.
US08251635B2 Apparatus and method for supplying articles to processing tool
An article supply apparatus includes a container storage rack for storing containers, and an article storage rack for storing articles taken out of the container. The article supply apparatus includes a transfer apparatus for transporting the articles between the container of the container storage rack and the article storage rack. The article supply apparatus includes a transportation apparatus for transporting the container between the transfer apparatus and the container storage rack, and a supply apparatus for taking required articles out of the article storage rack, and supplying the articles to a processing tool and supply the articles from the processing tool to the article storage rack.
US08251630B2 Bag handling assembly for a grain bag unloading apparatus
A grain bag handling assembly for a grain bag unloading apparatus having an auger assembly with an input end which is inserted into a mouth of an elongated grain bag and a remote output end. The grain bag handling assembly includes a rotatably mounted spool onto which the grain bag is rolled. The spool has a changeable diameter. A drive motor is provided for rotating the spool.
US08251629B2 Medication dispensing apparatus
A medication dispenser provides automation to the steps of locating and acquiring medications to be administered to a patient. The medication dispenser includes an enclosure providing a secure environment for storing medications in multiple sized medication-storage bins. The medication storage bins are hung in storage racks located within the enclosure. A robot system is also provided within the enclosure for moving bins between the storage racks and a medication dispensing area. The medication dispensing area includes doors configured to open to define an opening for passing a selected bin through the enclosure. In some embodiments, the doors provide a variable-sized opening and, in some instances, the opening matches the size of a bin containing medications selected for dispensing.
US08251624B2 Inflatable dunnage bag with protected inflator valve
A dunnage bag is fabricated of thermoplastic sheet material joined together to form an air cushion including being joined to form an inflation panel edge seam. An inflation opening to the air cushion is defined between two layers of thermoplastic sheet material adjacent a terminus of the panel edge seam. Two layers of the thermoplastic sheet material extend from the inflation panel edge seam and inflation opening, and the two layers are joined together by an inflation panel seam pattern to form an inflation panel. The inflation panel seam pattern further defines an inflation area communicating with the inflation opening and with an inflation valve sealed to the inflation panel in the inflation area, for supplying inflation air from the inflation valve through the inflation panel and into the air cushion. The inflation area is preferably an elongated sinuous tube. This configuration protects the inflation valve and contributes to the integrity of the dunnage bag. The thermoplastic sheet material is substantially transparent, so that cargo inspections may be made without removing the dunnage bags.
US08251619B2 Hole machining method for circuit board
A hole machining method includes drilling two holes are drilled at opposite ends of a drilling area as a start point and an end point. The number of holes between the start point and the end point is determined. A dividing point and a number of holes L are determined according to determined equations. Holes are drilled in the dividing point, and between the start point and the dividing point according to the determined equations.
US08251618B2 Cutting insert, cutting tool, and cutting method using cutting tool
A cutting insert includes upper, a lower, and side surfaces a corner cutting edge and a first cutting edge; a rake surface; and a protruding portion. The protruding portion is located inner side on the upper surface with respect to the rake face and comprises a first surface, a second surface, and a third surface located between the first surface and the second surface. The rake face includes a first rake face and a second rake face. An angle between an intersection line of the third surface and the second rake face and the first side is 90 degree or less as viewed from the upper surface.
US08251614B2 Electrical power system for a subsea system
An electrical power system for stationary or movable subsea loads (7) provides one common feeder for multiple electric motors which can be individually controlled. Operational flexibility and operational safety for operation in varying water depths is provided by encapsulating electrical functional element (6) of a subsea power system with a subsea electrical distribution system (5) individually or in-groups. Electrical functional element (6) and their semi-conductor elements are arranged within at least one fluidized internal pressure casing (13). An external pressure casing (12) is provided for the subsea electrical distribution system (5) and/or other components of the subsea system. A high frequency power transmission to the subsea pressurized distribution system (5) with pressurized semi-conductor components reduces weight and size of subsea transformers (4b) and cables (9) employed in subsea systems (10).
US08251612B2 Tidal responsive barrier
A tidal barrier is provided that may be selectively deployed in response to tidal changes. The tidal barrier includes a net having a tensile membrane with an upper edge and a lower edge. The lower edge has a plurality of anchor points for affixing the lower edge to a seabed below a body of water. The tidal barrier further includes a bladder affixed to the upper edge and having a valve for selectively inflating and deflating the bladder. The bladder has a sufficient volume to cause the upper edge of the membrane to rise to a surface of the body of water when the volume is inflated with a gas. A pump is disposed in proximity to the tensile membrane and is in fluid communication with the valve of the bladder. The pump has a controller for selectively prompting the pump to inflate and deflate the bladder with the gas.
US08251610B2 Apparatus for the creation of outer surfaces for structures
The present invention provides an apparatus for creating an outer surface effect of a structure wherein at least one wall of the structure defines a support surface, the apparatus comprising means defining a covering surface which overlies the support surface but is movable therefrom, so that a quantity of material to create the outer surface effect can be positioned between the support surface and the covering surface, and wherein the covering surface is in the form of a panel.
US08251607B2 System and apparatus of fluid storage using paver blocks
Systems and methods for a porous pavement system are described. The porous pavement system includes paver blocks designed to facilitate water seepage between the paver blocks and to permit water storage within the blocks. The paver blocks may be cabled together to create paving units that facilitate installation and maintenance of the pavement system. The porous pavement system provides improved management of stormwater, reducing runoff and facilitating infiltration of stormwater into the subgrade below the paving system.
US08251606B2 Fastener and assembly utilizing the same
A fastener is disclosed. The fastener includes a housing, wherein the housing forms a housing cavity, wherein the housing cavity includes at least one recess; a cage at least partially disposed in said housing cavity, wherein an outer surface of the cage is spaced apart from an inner surface of the housing that forms the housing cavity, wherein the cage defines a cage cavity, and a plurality of passages aligned with said at least one recess; a plurality of retaining members at least partially retained within said plurality of passages; and a plunger at least partially disposed in said cage cavity, wherein said plunger is at least partially movable within said cage cavity between a first position to cause said one or more retaining members to be displaced radially outwardly thereby mechanically coupling said housing to said cage, and a second position to allow said one or more retaining members to be displaced radially inwardly thereby allowing said housing to be uncoupled from said cage.
US08251605B2 Ball and socket joint
A ball and socket joint, especially for the wheel suspension of a motor vehicle, with a ball pivot (1), which is equipped with a first spheroidal bearing surface (3) mounted pivotably and rotatably in a housing (2). A roller bearing (5) is present between the first spheroidal bearing surface (3) and another spheroidal bearing surface (4), which is mounted in the housing (2) and is connected to the ball pivot (1). The roller bearing (5) is a roller bearing transmitting radial and axial forces.
US08251604B2 Device for securing a spoke to the rim of a spoked wheel
A device (1) for securing to the rim (11) of a spoked wheel a stud (2) connected to a spoke, includes:—a screw (3) adapted to be inserted in a through hole, made in the rim (11), which has a seat (4) adapted to receive the head (5) of the screw (3);—a body (6), adapted to be secured to the rim (11) the screw (3), which has at last a threaded hole (7) adapted to receive the threaded shank of the screw (3) and a seat (8) adapted to receive a rounded head (9) of the stud (2), which is connected in an articulated manner to the body (6);—a sealing ring (10) inserted between the rim (11) and the body (6). The head (5) of the screw (3) and the corresponding seat (4) present in the rim (11) preferably have a countersunk shape.
US08251594B2 Pluggable electronic unit with transmission power adjustment capability
The present relates to pluggable electronic unit with transmission power adjustment capability such as for example small form-factor pluggable transceivers. The pluggable electronic unit with transmission power adjustment capability may comprise a power adjustment unit. By verifying the transmitted power is sufficient or could be reduced, it is possible to regulate transmission power of a transceiver autonomously within the pluggable electronic unit itself.
US08251591B2 Optical interconnection assemblies and systems for high-speed data-rate optical transport systems
Fiber optic assemblies and systems for high-speed data-rate optical transport systems are disclosed that allow for optically interconnecting active assemblies to a trunk cable in a polarization-preserving manner. The fiber optic assembly includes at least first and second multifiber connectors each having respective pluralities of first and second ports that define respective pluralities of at least first and second groups of at least two ports each. The first and second multifiber connectors are capable of being disposed so that the at least first and second groups of ports are located on respective termination sides of each ferrule. The fiber optic assembly also has a plurality of optical fibers that connect the first and second ports according to a pairings method that maintains polarity between transmit and receive ports of respective active assemblies. At least one of the first and second groups are optically connected without flipping the fibers, and at least one of the first and second groups are optically connected by flipping the fibers.
US08251590B2 Anti-rotation bearing assembly and bearing
A bearing component and bearing assembly are disclosed. The bearing component includes structure for providing a hard rotation stop, in one embodiment, the anti-rotation structure includes a slot formed in at least one bearing component having a surface for supporting a bearing shell. The slot has a longitudinal axis at an oblique angle to a plane perpendicular to the surface for supporting the bearing shell. In other embodiments, a groove extends radially outward from a surface of at least one component for supporting a bearing shell to a side of the component. The groove has a depth that increases as a function of distance in a direction parallel with a center axis of the component.
US08251584B2 Anatomical imaging system with centipede belt drive
An anatomical imaging system comprising: a CT machine; and a transport mechanism mounted to the base of the CT machine, wherein the transport mechanism comprises a fine movement mechanism for moving the CT machine precisely, relative to the patient, during scanning.
US08251583B2 Removable radiation sensor for dental imaging systems
A removable radiation sensor for connecting to a panoramic dental radiation imaging system. The sensor includes a radiation sensor unit mounted in a housing. Connector bearings are positioned within the housing so as to engage with a pair of connector pins provided as part of the upright support of the imaging system. A lock pin within the housing is selectively slidable between Locked and Unlocked, and biased toward Locked. The lock includes a locking pin with a groove, and when the groove is aligned with the respective connector pin, the lock is unlocked, and that connector pin is slidable axially within the bearings. When the groove is not aligned with the connector pin, the lock is locked, the locking pin engaging with a groove formed for that purpose in the connector pin. The sensor has a field-replaceable electrical connector, to reduce maintenance cost.
US08251581B2 Magnetic element temperature sensors
The temperature sensors (26,64,96) preferably include a plurality of individual, magnetically susceptible temperature sensor elements (28-34,66,92), as well as optional magnetic field-responsive data elements (38,40,20) adapted for attachment to object (44) or to a substrate (82) in turn attached to object (44). The temperature sensor elements (28-34,66,92) preferably have magnetic bodies (22,70) exhibiting a re-magnetization response under the influence of an applied alternating magnetic field, which is different below and above a set point temperature, normally the Curie temperature of the magnetic body (22) or an adjacent sheath (74,94). The temperature sensors (26,64,96) are used in conjunction with a detector (46) operable to generate a magnetic field of magnitude sufficient to cause re-magnetization responses of the temperature sensor elements (28-34,66,92) and optional data elements (38,40,20), to detect such responses, and to use the detected responses to determine the temperature of object (44) by means of a decoding algorithm. The temperature sensors (26,64,96) can be used in closed-loop heating systems (98) capable of controlling the heating of an object (114).