最新美国发明专利第2012-07-17期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

Document	Document Title
US08222554B2	Key input apparatus of portable terminal A key input apparatus of a portable terminal, which is pushed or slid in various directions so as to make contact with contact pieces is provided. The key input apparatus includes a switch part having a plurality of contact pieces disposed in a circumference of the switch part, the switch part being mounted in a main body of the portable terminal; and a key part being pushed or slid so as to make contact with the contact pieces, the key part corresponding to the switch part.
US08222553B2	Metal domed contact component and card comprising it The invention relates to a domed contact component controlled by mechanical activation, which comprises an outer static conducting member (10), an inner static conducting member (12) and a resilient metal contact dome (18) which is in constant and static contact with the outer static conducting member (10). The dome (18) has a central contact part and a linking part, the periphery of which is electrically connected and mechanically linked to the outer static conducting member (10). The linking part comprises arms (22) having a portion (26) with elastic properties in the radial direction, and a stud (24) for fastening the outer static conducting member. Application to bank cards provided with keys.
US08222541B2	Avionics chassis An avionics chassis comprises a composite housing, a radio wave shield, and a lightning strike conductive path, wherein the radio wave shield attenuates electromagnetic interference entering and leaving the housing, and the lightning strike conductive path directs the current from a lightning strike away from an interior of the housing.
US08222538B1	Stackable via package and method A stackable via package includes a substrate having an upper surface and a trace on the upper surface, the trace including a terminal. A solder ball is on the terminal. The solder ball has a solder ball diameter A and a solder ball height D. A via aperture is formed in a package body enclosing the solder ball to expose the solder ball. The via aperture includes a via bottom having a via bottom diameter B and a via bottom height C from the upper surface of the substrate, where A
US08222533B2	Low profile photovoltaic (LPPV) box A low profile photovoltaic connection system for placement in space restricted areas. The connection system includes a connection box, diodes, and heat sinks inside of the connection box. The heat sink element is maintained in contact with the diode element such that the heat sink dissipates heat externally of the junction box and the contacts are arranged with a flat surface parallel to the solar panel to reduce vertical elevation of the junction box when mounted to the solar panel.
US08222532B2	Method for manufacturing a wiring board A wiring board includes: an uppermost wiring layer formed on a prescribed number of underlying wiring layers, a portion of the uppermost wiring layer being exposed and used as a pad for connection with a component to be mounted; and an insulation resin layer covering the uppermost wiring layer, wherein the thickness of the portion of the uppermost wiring layer is larger than that of other portions thereof.
US08222526B2	High voltage bushing and flange with interior seal A high voltage bushing and flange with an interior seal. The high voltage bushing includes an outer insulating material. The high voltage bushing includes a flange with an interior seal comprised of at least two flange O-ring channels; at least two O-rings; a sealant channel; and a quantity of sealant filling the sealant channel.
US08222518B2	Photovoltaic roofing panel Disclosed is a photovoltaic roofing panel including at least one photovoltaic collector strip and a substrate configured to be disposed on a roof deck, the at least one photovoltaic collector strip being fixedly associated with the substrate.
US08222515B2	Electrolyte for photoelectric conversion elements, and photoelectric conversion element and dye-sensitized solar cell using the electrolyte An object of the present invention is to provide an electrolyte for photoelectric conversion elements, and a photoelectric conversion element and a dye-sensitized solar cell using the electrolyte, wherein high energy conversion efficiency can be achieved while substantially not including iodine. The electrolyte for a photoelectric conversion element of the present invention includes an ionic liquid (A) and a carbon material (B). The carbon material (B) is a carbon material (B1) displaying a pH, measured by a pH measuring method specified in Japanese Industry Standard (JIS) Z8802, of from 2 to 6 and/or a boron-modified acetylene black (B2). A content of the carbon material (B) is from 10 to 50 parts by mass per 100 parts by mass of the ionic liquid (A).
US08222514B2	Backskin material for solar energy modules A solar energy module includes one or more solar cells, each having a front side for receiving light and an opposite back side. An encapsulant material covers at least the front side of each of the solar cells. The solar energy module also includes a backskin layer formed from a cross-linked mixture of high density polyethylene (HDPE) and acid copolymer bonded to the back side of each of the solar cells.
US08222511B2	Thermoelectric device A thermoelectric device comprises a plurality of semiconductor elements comprising a first set of semiconductor elements and a second set of semiconductor elements, which include dissimilar electrical properties. The semiconductor elements are oriented in a substantially hexagonal array that includes rows in which semiconductor elements of the first and second sets of semiconductor elements alternate. The thermoelectric device also comprises a first set of electrical conductors and a second set of electrical conductors; each of the first set of electrical conductor being electrically coupled to the first end of a semiconductor element of the first set of semiconductor elements and the first end of a semiconductor element of the second set of semiconductor elements, each of the second set of electrical conductors are electrically coupled to the second end of a semiconductor element of the first set of semiconductor elements and the a second end of a semiconductor element of the second set of semiconductor elements such that the plurality of semiconductor elements are electrically coupled to each other in series.
US08222507B1	System and method for capture and rendering of performance on synthetic musical instrument Techniques have been developed for capturing and rendering musical performances on handheld or other portable devices using signal processing techniques suitable given the somewhat limited capabilities of such devices and in ways that facilitate efficient encoding and communication of such captured performances via wireless networks. The developed techniques facilitate the capture, encoding and use of gesture streams for rendering of a musical performance. In some embodiments, a gesture stream encoding facilitates audible rendering of the musical performance locally on the portable device on which the musical performance is captured, typically in real time. In some embodiments, a gesture stream efficiently codes the musical performance for transmission from the portable device on which the musical performance is captured to (or toward) a remote device on which the musical performance is (or can be) rendered. Indeed, is some embodiments, a gesture stream so captured and encoded may be rendered both locally and on remote devices using substantially identical or equivalent instances of a digital synthesis of the musical instrument executing on the local and remote devices.
US08222501B2	Plants and seeds of corn variety CV970480 According to the invention, there is provided seed and plants of the corn variety designated CV970480. The invention thus relates to the plants, seeds and tissue cultures of the variety CV970480, and to methods for producing a corn plant produced by crossing a corn plant of variety CV970480 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV970480 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV970480.
US08222497B1	Maize variety inbred PHV6T A novel maize variety designated PHV6T and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PHV6T with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PHV6T through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PHV6T or a locus conversion of PHV6T with another maize variety.
US08222491B2	Soybean variety A1016190 The invention relates to the soybean variety designated A1016190. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1016190. Also provided by the invention are tissue cultures of the soybean variety A1016190 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1016190 with itself or another soybean variety and plants produced by such methods.
US08222488B2	Enhancing expression of value-added genes by transgenic expression of tombusvirus-based P19 gene mutants A method of enhancing expression of at least one desired gene product in a plant, comprises transgenically introducing a Tombusvirus p19/R43W mutant gene (SEQ. ID NO: 3) into the plant, expressing at least one desired gene product in the plant, wherein expression of said product is susceptible to RNA silencing; and co-expressing the transgenically introduced p19/R43W, to produce an amount of P19/R43W mutant protein (SEQ. ID NO: 4) sufficient to suppress silencing of expression of said desired gene product.
US08222485B2	Generation of plants with improved pathogen resistance The present disclosure is directed to plants that display a modified pathogen resistance phenotype (e.g., increased nematode resistance) due to altered expression of an NMR nucleic acid. The invention is further directed to methods of generating plants with a modified pathogen resistance phenotype.
US08222483B2	Cytokinin oxidase sequences and methods of use Methods and compositions for modulating plant development are provided. Polynucleotide sequences and amino acid sequences encoding cytokinin oxidase polypeptides are provided. The sequences can be used in a variety of methods including modulating root development, modulating floral development, modulating leaf and/or shoot development, modulating seed size and/or weight, modulating tolerance under abiotic stress, and modulating resistance to pathogens. Polynucleotides comprising CKX promoters are also provided. The promoters can be used to regulate expression of a sequence of interest. Transformed plants, plant cells, tissues, and seed are also provided.
US08222482B2	Modulating plant oil levels Methods and materials for modulating (e.g., increasing or decreasing) oil levels in plants are disclosed. For example, nucleic acids encoding oil-modulating polypeptides are disclosed as well as methods for using such nucleic acids to transform plant cells. Also disclosed are plants having increased oil levels and plant products produced from plants having increased oil levels.
US08222479B2	Recombinant organism and protein produced by the recombinant organism The present invention relates to a recombinant organism having any one of nucleic acids (i) to (iv) introduced therein: (i) a nucleic acid having a base sequence of SEQ ID NO: 1; (ii) a nucleic acid encoding a protein having an amino acid sequence of SEQ ID NO: 2; (iii) a nucleic acid encoding a dragline protein and having a sequence identity of 90% or more with the nucleic acid (i); (iv) a nucleic acid which encodes a dragline protein and hybridizes with a complementary chain of the nucleic acid (i) under stringent conditions.
US08222476B2	Absorbent articles with impending leakage sensors In accordance with one embodiment of the present disclosure an absorbent article capable of indicating the presence or absence of urine as well as impending leakage of urine is disclosed. The absorbent article includes a substantially liquid impermeable layer, a liquid permeable layer, and an absorbent core positioned between the substantially liquid impermeable layer and the liquid permeable layer. A plurality of sensors are integrated into the article across the width of the article and positioned such that the sensors are in fluid communication with urine when provided by a wearer of the article. At least one of the sensors comprises a pH indicator. At least one of the sensors is capable of indicating the presence or absence of urine and at least one of the sensors is capable of indicating impending leakage of urine from the article.
US08222473B1	Isomerization of light paraffins A process for isomerizing light paraffins using a catalyst comprising an STI-type zeolite and at least one Group VIII metal. It has been found that the catalyst can selectively convert C6 paraffins into the more favorable higher octane C6 isomer, namely 2,3-dimethylbutane (RON=105), over the less favorable C6 isomer, namely octane 2,2-dimethylbutane (RON=94).
US08222470B2	Process for oligomerizing olefins using a catalyst based on silica-alumina A process for oligomerizing an olefinic hydrocarbon feed is described which consists of bringing said feed into contact with a catalyst comprising a silica-alumina, the silica content of said catalyst being in the range 5% to 95% by weight, said catalyst being prepared using a process comprising at least: a) mixing at least one alumina compound which is partially soluble in an acid medium with either at least one silica compound which is completely soluble in the reaction mixture or a combination formed by at least one silica compound and at least one alumina compound, said silica and alumina compounds being completely soluble in the reaction mixture, in order to form a solid precursor of said catalyst; b) hydrothermal treatment of the solid derived from step a) by calcining in moist air for a period in the range 4 to 7 hours.
US08222467B2	Production of high purity cumene from non-extracted feed and hydrocarbon composition useful therein A non-extracted hydrocarbon composition feed is substantially free of both C4− hydrocarbons and the C7+ aromatic hydrocarbons and contains benzene and benzene coboilers as well as sulfur, nitrogen, olefins and dienes.
US08222466B2	Process for producing a water stream from ethanol production In one embodiment, the invention is to a process for producing a water stream comprising the steps of hydrogenating acetic acid to form a crude ethanol product and separating at least a portion of the crude ethanol product in at least one column of a plurality of columns into a distillate comprising ethanol and a residue comprising the water stream. The water stream preferably is essentially free of organic impurities other than acetic acid and ethanol.
US08222465B2	Catalytic process for continuously generating polyols A catalytic process for generating at least one polyol from a feedstock comprising cellulose is performed in a continuous manner. The process involves, contacting, continuously, hydrogen, water, and a feedstock comprising cellulose, with a catalyst to generate an effluent stream comprising at least one polyol, water, hydrogen, and at least one co-product. The water, hydrogen, and at least one co-product are separated from the effluent stream and recycled to the reaction zone. The polyol is recovered from the effluent stream.
US08222457B2	Coordination compounds of the boron group A coordination compound of an element of the boron group, the production of the compound and methods of using the compound as an additive, stabilizer, catalyst, co-catalyst, activator for catalyst systems, conductivity improver, and electrolyte.
US08222456B2	Facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers and uses thereof The present invention discloses methods of use of facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers, including, but not limited to, pharmaceutical uses of the polymers and oligomers as antimicrobial agents and as antidotes for hemorrhagic complications associated with heparin therapy. The present invention also discloses novel facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers, compositions of the novel polymers and oligomers, including pharmaceutical compositions, and methods of designing and synthesizing the facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers.
US08222455B2	Polycationic viscoelastic compositions Viscoelastic compositions are disclosed herein containing an effective amount of one or more random or structurally defined polycationic quaternary ammonium compounds for controlling the viscoelasticity of the composition. In one aspect, the present technology provides polycationic quaternary ammonium compounds that comprise bis-quaternary compound. The bis-quaternary compounds of the present technology can be symmetric or dissymmetric. In another aspect, the present technology provides viscoelastic well bore treatment fluids comprising water, and at least one polycationic quaternary ammonium compound that comprises a bis-quaternary compound. In another aspect, the present technology provides polycationic carboxylates. Preferred viscoelastic compositions of the present technology maintain viscoelasticity at a temperature greater than about 80° C., preferably greater than about 100° C. or 110° C. when the amount of the one or polycationic quaternary compounds is less than about 10% by weight based on the total weight of the composition.
US08222452B2	Method for producing optically active amines The present invention provides a method for producing chiral amines, comprising asymmetric transfer hydrogenation of imine compounds in the presence of a hydrogen donor compound and an iridium(III) complex having a chiral prolinamide compound as a ligand. The present invention is useful for production of chiral amines in an efficient manner in terms of their optical and chemical yields.
US08222451B2	Histone deacetylase inhibitors and methods of use thereof The invention provides novel classes of HDAC inhibitors. Methods of sensitizing a cancer cell to the cytotoxic effects of radiotherapy are also provided as well as methods for treating cancer and methods for treating neurological diseases. Additionally, the invention further provides pharmaceutical compositions comprising an HDAC inhibitor of the invention, and kits comprising a container containing an HDAC inhibitor of the invention.
US08222448B2	Processes for production of 2-bromo-2,2-difluoroethanol and 2-(alkylcarbonyloxy)-1, 1-difluoroethanesulfonic acid salt Disclosed is a process for producing 2-bromo-2,2-difluoroethanol, which comprises reducing a bromodifluoroacetic acid derivative represented by the formula [1] by using an ate hydride complex as a reducing agent. 2-Bromo-2,2-difluoroethanol thus produced can be used as the starting material to carry out the esterification step, the sulfination step and the oxidation step in this order, thereby producing a 2-alkylcarbonyloxy-1,1-difluoroethanesulfonic acid salt, wherein A represents a substituted or unsubstituted linear, branched or cyclic alkoxy group having 1 to 20 carbon atoms, a substituted or unsubstituted aryloxy group having 6 to 15 carbon atoms, a heteroaryloxy group having 4 to 15 carbon atoms, or a halogen atom.
US08222447B2	Organic compounds Compounds of formula (I), which are 14-O-{[(optionally substituted hydroxy)cyclohexyl)sulfanyl]acetyl}mutilins further substituted at the cyclohexyl group by an acylated amino group, salts and solvates thereof, pharmaceutical compositions comprising such compounds and their use as a pharmaceutical, e.g. for the treatment of diseases mediated by microbes and for the treatment of inflammation where microbes are mediating said inflammation.
US08222442B2	Phosphorylcholine group-containing compound, method of manufacturing a phosphorylcholine group-containing compound, surface-modifying agent, and a method of modifying a surface using a surface-modifying agent A phosphorylcholine group-containing compound that is a structure having a phosphorylcholine group represented by the following formula 1 and an amino group or a group derived from an amino group in an identical compound. (In the formula, m is 2 or more and 6 or less and p is 1 or 2. Each of X1, X2 and X3 is an alkyl group whose carbon number is 1 or more and 6 or less.)
US08222439B2	Process for the production of carboxylic acid esters The invention relates to a process for the production of carboxylic acid esters by esterification of carboxylic acids and/or transesterification of carboxylic acid esters with alcohols in the presence of a liquid metal catalyst, characterized in that the liquid metal catalyst is the alkaline earth metal salt of a carboxylic acid.
US08222436B2	Oxetane compound, active energy ray-curable composition, active energy ray-curable ink composition and inkjet recording method The present invention provides an oxetane compound represented by the following formula (1), and a active energy ray-curable composition including the oxetane compound as a polymerizable monomer. In formula (1), R11 to R15 each independently represents a hydrogen atom or an alkyl group; R21 to R24 each independently represents a hydrogen atom, an alkyl group, an alkoxy group or a halogen atom; R represents an alkyl group including a partial structure selected from an oxirane ring, an oxetane ring or a vinyl ether and having from 3 to 10 carbon atoms, or a vinyl group; and any adjacent groups among R21 to R24 and R may be bonded to each other to form a ring structure
US08222435B2	Dioxolane and dioxane derivatives and a process for their preparation The present invention relates to novel acylmethylene-1,3-dioxolanes and acylmethylene-1,4-dioxanes of the general formula (I) in which R1, R2, R3 and n have the meanings given in the description, and also a novel process for their preparation. Acylmethylene-1,3-dioxolanes and acylmethylene-1,4-dioxanes are important intermediates for the preparation of pyrazoles and anthranilamides, which can be used as insecticides.
US08222433B2	Axially asymmetric phosphorus compound and production method thereof An optically active compound represented by the following formula (5): wherein, in the formula (5), R1 and R2 may be the same or different are an alkyl group optionally having a substituent group selected from the group consisting of an alkoxy group and a halogen atom, a cycloalkyl group optionally having a substituent group selected from the group consisting of an alkoxy group and a halogen atom, an aryl group optionally having a substituent group selected from the group consisting of an alkyl group, an alkoxy group and a halogen atom, an alkoxy group optionally having a substituent group selected from the group consisting of a halogen atom and an aryl group or an aryloxy group optionally having a substituent group selected from the group consisting of an alkyl group, an alkoxy group and a halogen atom; a1 and a2 independently are 0 or 1; and * is axial asymmetry.
US08222431B2	Process for synthesizing phosphonic and phosphinic acid compounds The present invention is directed to an improved process for synthesizing phosphonic and phosphinic acid chymase inhibitor compounds.
US08222426B2	Aromatic compound An aromatic compound of the following formula (1), (2), (5) or (6), wherein, Ar1 and Ar3 represent a tetra-valent aromatic hydrocarbon group or a tetra-valent heterocyclic group, and Ar2, Ar4, Ar5, Ar6 and Ar7 represent a tri-valent aromatic hydrocarbon group or a tri-valent heterocyclic group, A1 represents —Z1—, —Z2-Z3— or —Z4═Z5—, wherein Z1, Z2 and Z3 represent O, S or the like and Z4 and Z5 represent N, B, P or the like, X1, X2, X3, X4, X9, X10, X11, and X12 represent a halogen atom or the like.
US08222423B2	Bifunctional histone deacetylase inhibitors In recognition of the need to develop novel therapeutic agents and efficient methods for the synthesis thereof, the present invention provides novel bifunctional, trifunctional, or multifunctional compounds for inhibiting histone deacetylases, and pharmaceutically acceptable salts and derivatives thereof. The present invention further provides methods for treating disorders regulated by histone deacetylase activity (e.g., proliferative diseases, cancer, inflammatory diseases, protozoal infections, hair loss, etc.) comprising administering a therapeutically effective amount of an inventive compound to a subject in need thereof. The present invention also provides methods for preparing compounds of the invention.
US08222422B2	Crystal of benzimidazole compound Provided is a crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole showing an X-ray powder diffraction pattern having characteristic peaks at interplanar spacings (d) of 10.06±0.2, 8.70±0.2, 6.57±0.2, 5.59±0.2 and 4.00±0.2 Angstroms. The present invention provides a stable antiulcer drug superior in the absorbability.
US08222417B2	Compound having 11β-HSD1 inhibitory activity The present invention provides compounds having excellent 11β-HSD1 inhibitory activity.A compound represented by the following formula (I): [wherein X1 represents an oxygen atom, or the formula —(CR11R12)p—, etc., Y1 represents a hydrogen atom, a hydroxyl group, etc., Z1 represents an oxygen atom or the formula —(NR14)—, R1 represents a hydrogen atom, a halogen atom, a cyano group, a C1-4 alkyl group, a C1-4 alkyl group substituted with 1 to 3 halogen atoms, a C1-4 alkoxy group, a C1-4 alkoxycarbonyl group, a carboxyl group, a carbamoyl group, or an amino group, and m represents an integer of 1 or 2, and R2 represents a hydrogen atom or a C1-4 alkyl group, and n represents an integer of 1 or 2].
US08222414B2	Indole compounds as an inhibitor of cellular necrosis The present invention relates to new indole compounds, pharmaceutically acceptable salts or isomers thereof which are useful for the prevention or treatment of cellular necrosis and necrosis-associated diseases. The present invention also relates to a method and a composition for the prevention or treatment of cellular necrosis and necrosis-associated diseases, comprising said indole compounds as an active ingredient.
US08222412B2	Preparation of aminopyrimidine compounds A 2-(N-methyl-N-methanesulfonylamino)pyrimidine compound of the formula (3): [R is a hydrocarbyl group], is prepared by the steps of: (I) reacting an isobutyrylacetate ester with 4-fluorobenzaldehyde and urea in the presence of a protonic compound and a metal salt; (II) oxidizing the reaction product of the step (I); (III) reacting the oxidation product of the step (II) with an organic sulfonyl halide or an organic sulfonyl anhydride; and (IV) reacting the reaction product of the step (III) with N-methyl-N-methanesulfonamide.
US08222409B2	Nitrogen-containing heterocyclic compound A nitrogen-containing heterocyclic compound is represented by Formula (I): wherein R1 represents a hydrogen atom, a substituted or unsubstituted alkyl group having 1 to 20 carbon atoms, or a substituted or unsubstituted alkoxy group having 1 to 20 carbon atoms; A represents a heterocyclic residue that contains at least one nitrogen atom and forms a six-membered aromatic heterocyclic ring; and n represents an integer of from 1 to 3.
US08222408B2	Process for preparing acyl amide compounds A process for preparing acyl amide compounds is described, in which a recrystallized o-nitrophenoxy carbonyl compound is hydrogenated with hydrogen gas in the presence of a nickel sponge metal catalyst with ring closure to form a benzoxazine, which is then reacted with an acyl halide to give the corresponding acyl amide compound.
US08222406B2	Process for preparing heterocycles Provided is a process for preparing a heterocycle by catalytic reaction of an aromatic dinitrile with an amino alcohol, wherein the process includes: initially charging into a reaction vessel the amino alcohol and a catalyst to produce a reaction mixture; adding the aromatic dinitrile into the reaction mixture, which is maintained at a reaction temperature, wherein no solvent other than the amino alcohol of formula (III) is added to the reaction mixture prior to and/or during the catalytic reaction; and after completion of the catalytic reaction, completely replacing, or substantially completely replacing, unreacted amino alcohol with a nonpolar solvent to obtain the heterocycle, wherein the unreacted amino alcohol is present in an amount of not more than 20 wt. %, preferably 3-10 wt. % or less, based on a total weight of the heterocycle.
US08222403B2	Heteroaromatic phthalonitriles Disclosed are an oligomer and a phthalonitrile monomer having the formulas: M is a metal or H. The value n is an integer greater than or equal to 1 for the oligomer and greater than or equal to 0 for the phthalonitrile monomer. Ar1 and Ar2 are independently selected aromatic- or heterocyclic-containing groups. Ar1, Ar2, or both are heteroaromatic or heterocyclic groups containing a nitrogen, sulfur, or oxygen heteroatom. Also disclosed are thermosets and pyrolyzed materials made from the phthalonitrile monomer.
US08222402B2	Preparation process A process for preparing compounds of the formula (I) in which R1.1, R1.2, R1.3 and R2 are as defined in the description.
US08222397B2	Methods of optimal purification of nucleic acids and kit for use in performing such methods A method and kit which allow the use of a discrete amount of a binding matrix to first purify nucleic acids from a medium under a first set of binding conditions wherein the amount of nucleic acid bound to the binding matrix is essentially independent of the amount of surface area of the definable amount of the binding matrix, followed by a second purification step wherein the nucleic acids are bound to a discrete amount of binding matrix under a second set of binding conditions wherein the amount of nucleic acid bound to the binding matrix is essentially dependent on the amount of surface area of the definable amount of the binding matrix, thus providing a discrete quantity of nucleic acid.
US08222394B2	MicroRNA molecules In Caenorhabditis elegans, lin-4 and let-7 enclode 22- and 21-nucleotide RNAs, respectively, that function as key regulators of developmental timing. Because the appearance of these short RNAs is regulated during development, they are also referred to as “small temporal RNAs” (stRNAs). We show that many more 21- and 22-nt expressed RNAs, termed microRNAs, (miRNAs), exist in invertebrates and vertebrates, and that some of these novel RNAs, similar to let-7 stRAN, are also highly conserved. This suggests that sequence-specific post-transcriptional regulatory mechanisms mediated by small RNAs are more general than previously appreciated.
US08222392B2	Kit for detection of telomerase reverse transcriptase nucleic acids The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for changing the proliferative capacity of cells and organisms, and for identification and screening of compounds and treatments useful for treatment of diseases such as cancers.
US08222390B2	Biomarkers for inflammatory bowel disease and irritable bowel syndrome The present invention provides compositions and their use in diagnosing and/or distinguishing inflammatory bowel disease and irritable bowel syndrome.
US08222388B2	Broadly expressing regulatory regions Regulatory regions suitable for directing expression of a heterologous polynucleotide in plant tissues, e.g., flower and silique tissues, are described, as well as nucleic acid constructs that include these regulatory regions. Also disclosed are transgenic plants that contain such constructs and methods of producing such transgenic plants.
US08222383B2	DNA encoding polypeptide capable of modulating muscle-specific tyrosine kinase activity Disclosed are DNA encoding a polypeptide which can modulate the activity of a muscle-specific tyrosine kinase, and others. The DNA is selected from the following members (a) to (d): (a) DNA comprising a specific nucleotide sequence; (b) DNA comprising a nucleotide sequence capable of hybridizing with a specific nucleotide sequence under stringent conditions; (c) DNA comprising a nucleotide sequence encoding an amino acid sequence having the substitution, deletion and/or addition of one or several amino acid residues in a specific amino acid sequence; and (d) DNA comprising a nucleotide sequence having 90% or higher homology to a specific nucleotide sequence.
US08222378B2	Neurotrophic growth factor, enovin There is disclosed an isolated nucleic acid molecule encoding a human neurotrophic growth factor designated enovin and having the amino acid sequence illustrated in FIG. 1, 21, 23 or 24 or encoding a functional equivalent, derivative or bioprecursor of said growth factor. The growth factor preferably comprises the amino acid sequence from position 27 to 139 of the sequence illustrated in FIG. 1, or a functional equivalent, derivative or bioprecursor thereof. The nucleic acid molecule encoding enovin can be used to transform a host cell, tissue or organism by including it in an appropriate vector. The host cell, tissue or organism and the vector also form part of the invention.
US08222376B2	KIR-binding agents and methods of use thereof The present invention relates to agents and methods that are capable of augmenting NK-mediated killing of target cells by reducing inhibitory KIR signalling without reducing the binding of KIR to HLA-C. As described herein, transduction of negative signaling via KIR, 5 upon binding of KIR to its HLA class I ligand, can involve a ligand-binding induced, conformational reorientation of the KIR molecules allowing interactions to form between adjacent KIRs in specific domains, leading to accelerated clustering. Methods and agents such as mono-clonal antibodies for reducing KIR-mediated inhibition of NK cell cytotoxicity without reducing or blocking HLA-binding by, e.g., reducing or blocking dimerization of KIR, are provided.
US08222372B2	Whey protein hydrolysate The present invention relates to a method of producing a whey protein hydrolysate using a microbial endopeptidase which specifically cleaves on the carboxy terminal side of arginine or lysine. The invention also relates to use of such whey protein hydrolysate in sports drinks or in clinical nutrition.
US08222371B2	vWFA and/or ANT—IG domain containing proteins Proteins (INSP141, INSP142, INSP143, and INSP144) identified as anthrax receptor-like proteins containing von Willebrand factor A (vWFA) and Anthrax receptor extracellular (ANT_IG) domains and the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease are described.
US08222369B2	Process for preparing macrocyclic compounds Disclosed is a process for preparing a macrocyclic compound of the formula (I) wherein a hydroxyl-substituted macrocyclic compound of formula (3) is reacted with a sulfonyl-substituted compound of formula QUIN: The compounds of formula (I) are potent active agents for the treatment of hepatitis C virus (HCV) infection.
US08222368B2	Cosmetic and/or pharmaceutical composition comprising as an active principle at least one peptide and use of this peptide A cosmetic and/or pharmaceutical composition contains, as an active ingredient, at least one peptide from SEQ ID No1 to SEQ ID No8. The use of this peptide as an active ingredient for preparing compositions for inducing, increasing or restoring melanin synthesis in melanocytes of the skin or dermal papilla is also disclosed.
US08222364B2	Composition including a siloxane and a method of forming the same A composition includes a siloxane of the formula: (RMe2SiO1/2)a(MeRSiO2/2)b(RSiO3/2)c(SiO4/2)d wherein a is at least 2, b is from 3 to 20, c is from 0 to 10, d is from 0 to 10, and each R is independently of the formula —CR′2—CR′2—Y—Z or CR′2—CR′2—Z, wherein each R′ is independently a hydrogen atom or a C1 to C10 hydrocarbyl free of aliphatic unsaturation so long as at least one R′ is a hydrogen atom, Y is a divalent organic group, and Z is a polycyclic group containing at least one aromatic ring. A method of making the siloxane includes charging (HMe2SiO1/2)a(MeHSiO2/2)b(HSiO3/2)c(SiO4/2)d, a platinum catalyst, and an alkene of the formula CR′2═CR′—Y—Z or CR′2═CR′—Z into a reactor to form the siloxane. The siloxane is useful as a component in holographic storage media for photopolymer-based holographic data storage applications. The siloxane exhibits excellent compatibility when mixed with a polymerizable component before the polymerizable component is cured. Furthermore, the siloxane exhibits excellent diffusion from polymers of the polymerizable component after partial and complete curing. The siloxane also has a high refractive index while maintaining the excellent compatibility and diffusion properties when mixed with polymerizable component.
US08222358B2	Process for producing propylene copolymers In a process for producing a propylene copolymer, propylene and at least one olefin monomer selected from ethylene and alpha olefins having 4 to 20 carbon atoms are contacted with a catalyst system comprising (a) a catalyst precursor comprising an organometallic compound and (b) an activator comprising a fluoroarylborate anion represented by the formula: Ct+[B(Ar)x(R)n]− where Ct+ is a cation capable of extracting an alkyl group from, or breaking a carbon-metal bond of, the organometallic compound; Ar is a fluorophenyl group; R is a fluoronaphthyl group and each of x and n is 1, 2, or 3, with the proviso that the sum of x+n=4.
US08222350B2	Low gloss polycarbonate compositions A thermoplastic composition comprising in combination a polycarbonate, a polycarbonate-polysiloxane copolymer, an impact modifier composition comprising ABS or BABS, a second impact modifier different from BABS or ABS, an aromatic vinyl copolymer, and optionally a gel-type low gloss additive, wherein the 60° gloss of the thermoplastic composition is measured to be less than or equal to 14 GU on 3 millimeter chips having a textured surface when measured according to ASTM D2457, and wherein a molded sample of the thermoplastic composition has a low temperature notched Izod impact at −40° C. of at least 65 KJ/m2 when measured according to ISO 180/1A is disclosed. The composition has low gloss, high low temperature impact, and a significantly improved balance of properties.
US08222347B2	Polyester-polycarbonate compositions A composition of matter comprising a thermoplastic resin composition derived from (i) a polyester derived from a cycloaliphatic diol, and an aromatic diacid; (ii) a polycarbonate derived from at least from 20 mole percent to 100 mole percent of an aromatic diol derived from structure II wherein R3 and R4 are independently selected from the group consisting of C1-C30 aliphatic, C2-C30 cycloaliphatic and C2-C30 aromatic groups, X is CH2 and m is an integer from 3 to 7, n is an integer from 1 to 4, p is an integer from 1 to 4, and from 0 mole percent to 80 mole percent of a second aromatic dihydroxy compound; and wherein the resin composition is transparent is disclosed. Also disclosed is a process to prepare this composition and articles therefrom.
US08222344B2	Weather resistant thermoplastic resin having excellent low gloss characteristics and method of preparing the same A weather resistant thermoplastic resin having excellent low gloss characteristics according to the present invention comprises a (meth)acrylic acid alkyl ester-based polymer (A) and an aromatic vinyl-cyanide vinyl based copolymer (B), wherein the (meth)acrylic acid alkyl ester-based polymer (A) forms a network-shaped disperse phase, and the aromatic vinyl-cyanide vinyl based copolymer (B) forms a continuous phase. The thermoplastic resin has excellent low gloss characteristics as well as superior weatherability, impact resistance, thermal resistance, delamination characteristics, and the like.
US08222340B2	Crosslinkable syrup copolymers with aminoalkyl (meth)acryloyl solvent monomers A pre-adhesive syrup polymer composition is described comprising an acid-functional (meth)acrylate copolymer and an aminoalkyl (meth)acryloyl solvent monomer, which when polymerized, provides a pressure-sensitive adhesive and pressure-sensitive adhesive articles.
US08222335B2	Fluorescent resin composition and solar battery module using the same This invention provides an organic rare earth metal complex, which emits fluorescence with a wavelength in the range of 550 to 900 nm, particularly a fluorescent resin composition comprising an ethylene-vinyl acetate copolymer containing 0.01 to 10% by mass of an organic rare earth metal complex represented by general formula wherein R represents an aliphatic or aromatic hydrocarbon group; Ln represents a rare earth metal; A represents group —CH═CH—; and n is 0 or 1. There are also provided a solar battery module using the fluorescent resin composition as a sealing material between a front cover and a crystalline silicon cell, and a solar battery with high conversion efficiency.
US08222334B2	Water-based inks for ink-jet printing The present invention relates to a water-based ink for ink-jet printing which not only satisfies a high optical density but also exhibits an excellent high lighter-fastness; a water dispersion used for the water-based ink; and a method for producing a print using the water-based ink. There are provided a water dispersion for ink-jet printing comprising (i) (A-1) polymer particles containing a colorant, (B) polymer particles and (C) the water-insoluble organic compound, or (ii) (A-2) self-dispersible pigment, (B) polymer particles and (C) the water-insoluble organic compound; a water-based ink containing the water dispersion; and a method for producing a print using the water-based ink.
US08222331B2	Injection molded article with poly(arylene ether)-block copolymer composition An injection molded article, such as a washing machine top, exhibiting an improved balance of heat resistance, ductility, and absence of molding-related defects is formed from a poly(arylene ether)-block copolymer composition. The composition includes specific amounts of a poly(arylene ether) having particular molecular weight characteristics, a hydrogenated block copolymer, and an organophosphate ester flame retardant.
US08222330B2	Polycarbonate resin composition having good flame retardancy A polycarbonate resin composition comprises: about 30 to about 99% by weight of a polycarbonate resin (A); and about 1 to about 70% by weight of a rubber modified aromatic vinyl based copolymer resin (B); and about 0.1 to about 40 parts by weight of a phosphorous compound (C) including a phosphate compound (C1) and a phosphonate compound (C2), per 100 parts by weight of a base resin including (A) and (B). The polycarbonate resin composition can have excellent flame retardancy and improved heat resistance by using a combination of at least two different phosphorous compounds.
US08222328B2	Reinforcing sheet for reinforcing toothed belt, and toothed belt and method for production thereof A method of manufacturing of the present invention is a method of manufacturing a toothed belt (10) having a belt part (13) and a tooth part (14) sticking out of the belt part (13). This method of manufacturing includes a first step of forming a reinforcing-sheet (12) including a fiber sheet and a coating film formed on the fiber sheet by drying the fiber sheet on which an aqueous treatment agent containing a first rubber latex and a first vulcanizing agent is applied, and a second step of reinforcing a surface of the tooth part (14) with the reinforcing-sheet (12) by vulcanizing the first rubber and a second rubber at the same time while adhering a rubber composition, which is a material for the tooth part (14), including the second rubber and a second vulcanizing agent to the reinforcing-sheet (12). The aqueous treatment agent contains the vulcanizing agent in the range of 10 parts by weight to 100 parts by weight for 100 parts by weight of the first rubber.
US08222326B2	Water-based ink composition for inkjet recording The invention provides a water-based ink composition for inkjet recording which contains vinyl polymer particles containing a styrene-acrylic acid copolymer in which the total content of the constitutional units derived from styrene monomer, acrylic acid, and methacrylic acid is 45% by mass or more; and at least one of an azo pigment represented by Formula (1), a tautomer thereof, a salt or hydrate thereof; and a water-based liquid medium, and which is excellent in discharge stability after a long-term storage or after aging at high temperatures: wherein, Q represents a heterocyclic group; W represents an alkoxy group, an amino group etc.; X1 and X2 each independently represent a hydrogen atom, an alkyl group etc.; R1 represents a hydrogen atom or a substituent; R2 represents a heterocyclic group; and n represents an integer of 1 to 4.
US08222313B2	Radiation curable ink containing fluorescent nanoparticles Radiation curable compositions, such as UV curable ink compositions, contain a polymeric dispersant, a curable material, that includes a carrier and at least one nanoscale fluorescent pigment particle and an optional non-fluorescent colorant. The fluorescent organic nanoparticle composition includes one or more fluorescent dyes dispersed in a polymeric matrix obtained by modified EA latex process or by emulsion polymerization. In a different embodiment, the nanoscale fluorescent pigment particle composition includes pigment molecules with at least one functional moiety, and a sterically bulky stabilizer compound including at least one functional group, the functional moiety of the pigment associates non-covalently with the functional group of the stabilizer, and the presence of the associated stabilizer limits the extent of particle growth and aggregation, to afford nanoscale-sized pigment particles.
US08222309B2	Elastomer porous material and method of producing the same In the elastomer porous material of the invention, when cells in a first observation region of a first cross section are observed at a certain magnification, cells having an aspect ratio a/b, wherein a represents the maximum diameter of each cell and b represents the length of the minor axis of that cell as measured in a direction orthogonal thereto, of 1.3 or less account for 70% or more of all cells in the first observation region, and, when cells in a second observation region of a second cross section orthogonal to the first cross section are observed at a certain magnification, cells having an aspect ratio a/b, wherein a represents the maximum diameter of each cell and b represents the length of the minor axis of that cell as measured in a direction orthogonal thereto, of 1.3 or less account for 70% or more of all cells in the second observation region.
US08222305B2	Process for producing liquid and gaseous products from gaseous reactants A hydrocarbon synthesis process (10) includes feeding gaseous reactants (18) into a slurry bed (14), allowing the gaseous reactants (18) to react catalytically, thereby to form liquid and gaseous hydrocarbon products, and subjecting a product mixture comprising liquid product and catalyst particles in a filtration stage to filtration, by passing the liquid product through a filtering medium (30) to separate catalyst particles from the liquid product. The gaseous products are withdrawn (23) and cooled to form a multi-phase product which is separated to produce at least a hydrocarbon condensate stream (88) and a tail-gas stream (84). At least a portion of the hydrocarbon condensate stream (88) is treated (96) to remove oxygenated components therefrom, producing a backflush condensate. From time to time, the filtering medium (30) of the filtration stage is backflushed by passing the backflush condensate through the filtering medium (30).
US08222304B2	Process for the treatment of a hydrophobic surface by an aqueous phase The invention relates to process for the treatment of a hydrophobic surface by a liquid film comprising an aqueous phase comprising the coating of said surface by the liquid whose aqueous phase comprises an effective amount of surface properties modifying agent and an active agent.
US08222300B2	Methods of treating parkinson's disease using halogenated volatile compounds The present invention provides methods of using halogenated volatile compounds, e.g., halogenated ether, for treating a neurological disorder, e.g., Parkinson's disease.
US08222298B2	Methods of correcting imbalance between bone resorption and bone formation and kits and compositions therefor Compounds, methods, uses, compositions, kits and packages for the treatment of imbalance between bone resorption and bone formation, based on uses of 4-phenyl-2-propionamidotetralin (4-P-PDOT) and analogs, derivatives, prodrugs, precursors thereof, and salts thereof, are described.
US08222296B2	Conjugates comprising a GABA- or glycine compound, pharmaceutical compositions and combinations thereof and their use in treating CNS disorders Conjugates of a gamma-aminobutyric acid (GABA) compound or a glycine compound and an analgesic drug are disclosed. Further disclosed are pharmaceutical compositions containing these conjugates and uses thereof in the treatment of CNS-associated diseases or disorders, optionally in combination with a psychotropic drug.
US08222295B2	Compositions comprising polyunsaturated fatty acid monoglycerides or derivatives thereof and uses thereof There are provided various compounds and compositions comprising polyunsaturated fatty acid monoglycerides and derivatives thereof. These compounds and compositions can be useful as cancer chemopreventive agents. They can also be useful for enhancing solubility of various active agents and enhancing their bioavailability.
US08222294B2	Combinations of an anti emetic agent and an enkephalinase inhibitor The present invention concerns combinations of an anti-emetic agent and an enkephalinase inhibitor for use in methods for treating diarrhea and/or gastroenteritis.
US08222287B2	Substituted anthra[1,2-D]imidazolediones and pharmaceutical utility thereof A heteroannelated anthraquinone derivative compound is provided. The heteroannelated anthraquinone derivative compound is represented by a formula (I): wherein R1 is a substituent being one selected from a group consisting of i) a first substituent being one selected from a group consisting of a hydryl group, an amino group, a nitro group, a hydroxyl group and a cyan group, ii) a second substituent being one selected from a group consisting of (CH2)nX, a straight (CH2)n alkyl group, a (CH2)n alkoxyl group, a branched (CH2)n alkyl group, a C3˜C12 nephthenic group, and a C3˜C12 cyclic alkoxyl group, wherein 1≦n≦12, and X is a halogen, iii) a third substituent being one selected from a group consisting of a straight C1˜C8 alkyl group with a double-bond, a C1˜C8 alkoxyl group with a double-bond, a branched C1˜C8 alkyl group with a double-bond and a C3˜C8 nephthenic group with a double-bond, and iv) a fourth substituent of a C5˜C12 heterocyclic group.
US08222285B2	1,3-dihydroxy substituted phenylamide glucokinase activators Compounds are provided which are glucokinase activators and thus are useful in treating diabetes and related diseases and have the structure wherein in the ring represents one or two double bonds; R1 is alkyl, aryl, arylalkyl, heteroaryl, or heteroarylalkyl; R2 is alkyl, aryl, arylalkyl, heteroaryl, or heteroarylalkyl; R5 is as defined herein; Z is O, S, S(O), S(O)2, or NR5a; X is S, O, N, NR3, or CR3; Y is NCR4 or NR4; R3, R4, and R5 are as defined herein; R8 is aryl, heteroaryl, —PO(OR9)(OR10), —PO(OR9)R10 or —P(O)(R9)R10 (wherein R9 and R10 are as defined herein)/R6 and R7 are independently H, halogen, or alkyl; m is 0 or 1; and n is 0 to 3, or a pharmaceutically acceptable salt thereof. A method for treating diabetes and related diseases employing the above compounds is also provided.
US08222284B2	Stable formulations of thiadiazole derivative The present invention provides formulation parameters and manufacturing conditions for stable pharmaceutical compositions comprising N-{4-(2,2-dimethyl-propionyl)-(5R)-5-[(2-ethylamino-ethanesulfonylamino)-methyl]-5-phenyl-4,5-dihydro-[1,3,4]thiadiazol-2-yl}-2,2-dimethyl-propionamide that minimize undesirable chiral conversion to the less active S enantiomeric form.
US08222282B2	Sulfonate salts of 2-amino-3-carbethoxyamino-6-(4-fluoro-benzylamino)-pyridine Flupirtine acid addition salts having the following formula (2), wherein R represents a substituted or unsubstituted C1-C12-alkyl or a substituted or unsubstituted C6-C10-aryl group, have been prepared.
US08222280B2	Ether compounds with nitrogen-containing 5-member heterocycle and uses thereof The invention relates to ether compounds with nitrogen-containing 5-member heterocycle, represented by formula (I): The groups are as defined as specification.The compounds of the present invention have broad-spectrum insecticidal activities, and they are very effective to lepidopterous pests, including Ostrinia nubilalis, sugarcane borer, summer fruit tortrix moth, Grapholitha inopinata, Lymantria dispar, Cnaphalocrocis medialis, Pyrausta nubilalis, Heliothis assulta, Grapholitha molesta, Plutella xylostella, Laphygma exigua, Prodenialitura and the like, especially more effective to Plutella xylostella and Laphygma exigua, and can have very good effects at very low doses. And the compounds of present invention have high activities to homopteran pests such as aphid. At the same time, some compounds of present invention have very good fungicidal activities, and can be used for preventing wheat powdery mildew, cucumber downy mildew, vegetable grey mould and the like.
US08222279B2	Small molecule insulin mimetics absent quinones Compounds of Formula I are described along with pharmaceutical formulations thereof, and methods of treating disorders such as diabetes and neurodegenerative diseases with such compounds.
US08222270B2	2×2×2 week treatment regimen for treating actinic keratosis with pharmaceutical compositions formulated with 2.5% imiquimod Pharmaceutical formulations and methods for the topical or transdermal delivery of 1-isobutyl-1H-imidazo[4,5-c]-quinolin-4-amine or 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine, i.e., imiquimod, to treat actinic keratosis with short durations of therapy, than currently prescribed for the commercially available ALDARA 5% imiquimod cream, as now approved by the U.S. Food & Drug Administration (“FDA”), are disclosed and described. More specifically, lower dosage strength imiquimod formulations to deliver an efficacious dose of imiquimod for treating actinic keratosis with an acceptable safety profile and dosing regimens that are short and more convenient for patient use than the dosing regimen currently approved by the U.S. Food & Drug Administration (“FDA”) for ALDARA 5% imiquimod cream to treat actinic keratosis are also disclosed and described.
US08222269B2	Tyrosine kinase inhibitors The present invention relates to 5H-benzo[4,5]cyclohepta[1,2-b]pyridine derivatives of formula (I) that are useful for treating cellular proliferative diseases, for treating disorders associated with MET activity, and for inhibiting the receptor tyrosine kinase MET. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
US08222268B2	Methods for reducing vein irritation The present invention provides compositions for delivering highly water-soluble drugs (such as vinca alkaloids) and methods of using such compositions.
US08222263B2	Inhibitors of hedgehog pathway The present invention is directed to a compound of Formula I or a single isomer thereof; where the compound is optionally as a pharmaceutically acceptable salt, hydrate, solvate or combination thereof, in addition to methods of preparing a Compound of Formula I, and methods of using a Compound of Formula I to treat cancer.
US08222262B2	Indazolyl derivatives useful as potassium channel modulating agents Potassium channel modulating agents of Formula Ia or Ib and enantiomers and mixtures enantiomers and N-oxides thereof, and pharmaceutically acceptable salts thereof, and their use in the preparation of pharmaceutical compositions. Also, pharmaceutical compositions useful for the treatment or alleviation of diseases or disorders associated with the activity of potassium channels, e.g., respiratory diseases, epilepsy, convulsions, vascular spasms, coronary artery spasms, renal disorders, polycystic kidney disease, bladder spasms, urinary incontinence, bladder outflow obstruction, irritable bowel syndrome, gastrointestinal dysfunction, secretory diarrhoea, ischaemia, cerebral ischaemia, ischaemic heart disease, angina pectoris, coronary heart disease, traumatic brain injury, psychosis, schizophrenia, anxiety, depression, dementia, memory and attention deficits, Alzheimer's disease, dysmenorrhea, narcolepsy, Reynaud's disease, intermittent claudication, Sjorgren's syndrome, migraine, arrhythmia, hypertension, absence seizures, myotonic muscle dystrophia, xerostomi, diabetes type II, hyperinsulinemia, premature labor, baldness, cancer, immune suppression, or pain.
US08222259B2	1,2,4-triazolo[4,3-c]pyrimidin-3-one and pyrazolo[4,3-e]-1,2,4-triazolo[4,3-c]pyrimidin-3-one compounds for use as adenosine A2a receptor antagonists Compounds of the Formula I wherein R1 and R2 together with the carbon atoms to which they are bonded optionally form a further heteroaromatic ring of the formula (II) as well as pharmaceutically acceptable salts, solvates, esters and prodrugs thereof are adenosine A2a receptor antagonists and, therefore, are useful in the treatment of central nervous system diseases, in particular Parkinson's disease.
US08222258B2	Stable pharmaceutical composition of freeze-dried tetrodoxin powder This invention relates to a stable pharmaceutical composition of freeze-dried tetrodotoxin powder which contains trace amount of tetrodotoxin, substances which can stabilizes tetrodotoxin, including disaccharide(s) or polyglucose(s) or analogues thereof and solvent(s), and solvents which can help tetrodotoxin dissolve.
US08222257B2	Phosphono-pent-2-en-1-yl nucleosides and analogs Compounds and compositions are provided for treatment, prevention, or amelioration of a variety of medical disorders associated with viral infections and/or cell proliferation. The compounds provided herein are 5-phosphono-pent-2-en-1-yl nucleosides and esters thereof.
US08222254B2	1, 2, 4-triazole derivatives as serotonergic modulators The invention relates to novel 5-hydroxytryptamine (5-HT) receptor modulator compounds of formula (I); wherein A, B, R1-R5, T, W, X, Y, Z and m are defined herein, to pharmaceutical compositions comprising these compounds and to their use in the treatment of conditions associated with 5-HT action.
US08222251B2	Pyridopyridazine compounds, compositions and methods of use The present invention relates generally to compounds represented in Formula I, pharmaceutical compositions comprising them and methods of treating of diseases or disorders such as cancer.
US08222249B2	Isoindoline compounds and methods of their use Provided herein are isoindoline compounds, pharmaceutical compositions comprising one or more of such compounds, and methods of their use for treating, preventing, or managing various diseases.
US08222247B2	Modulators of glucocorticoid receptor, AP-1, and/or NF-kappabeta activity and use thereof Novel non-steroidal compounds are provided which are useful in treating diseases associated with modulation of the glucocorticoid receptor, AP-1, and/or NF-κB activity, including metabolic and inflammatory or immune associated diseases or disorders having the structure of formula I or an enantiomer, diastereomer, tautomer, or a pharmaceutically-acceptable salt, thereof, wherein: A is a 5-, 6-, or 7-membered heterocyclo or heteroaryl, each containing 1, 2, or 3 heteroatoms selected from N, O, and S and substituted with one to four groups, R1, R2, R3, and/or R4; provided that (i) A is not tetrazole or (ii) if A is thienyl or furanyl then Z M is selected from alkyl, cycloalkyl, aryl, heterocyclo, and heteroaryl; Z is selected from alkyl, CF3, OH, cycloalkyl, heterocyclo, aryl, heteroaryl, —C(═O)NR8R9, —C(═O)R8, —C(NCN)NR8R9, —C(═O)OR8, —SO2R8, and —SO2NR8R9. Also provided are pharmaceutical compositions, combinations and methods of treating metabolic and inflammatory or immune associated diseases or disorders using said compounds.
US08222246B2	Substituted isoxazoles The present invention is concerned with novel hydroxy-methyl isoxazole derivatives of formula I wherein R1, R2 and R3 are as described herein, as well as pharmaceutically acceptable salts and esters thereof. The active compounds of the present invention have affinity and selectivity for GABA A α5 receptor. Further the present invention is concerned with the manufacture of the active compounds of formula I, pharmaceutical compositions containing them and their use as pharmaceuticals.
US08222244B2	Staurosporine derivatives as inhibitors of FLT3 receptor tyrosine kinase activity The present invention relates to the use of staurosporines derivatives for the preparation of a drug for the treatment of diseases involving deregulated FLT3 receptor tyrosine kinase activity, especially for the curative and/or prophylactic treatment of leukemias and myelodysplastic syndromes, and to a method of treating diseases involving deregulated FLT3 receptor tyrosine kinase activity.
US08222242B2	Nitric oxide releasing compounds Compositions comprising nitrosyl-cobinamide are provided. Also provided are methods for treating hypertension, which comprise administering therapeutically effective amounts of nitrosyl-cobinamide. Also provided are methods for producing nitrosyl-cobinamide.
US08222235B2	2-methylene-19-nor-(20R)-1α-hydroxy-bishomopregnacalciferol Compounds of formula I are provided where X1 and X2 are independently selected from H or hydroxy protecting groups. Such compounds may be used in preparing pharmaceutical compositions and are useful in treating a variety of biological conditions.
US08222233B2	Modifications of solid 3-sn-phosphoglycerides Methods for hydrolyzing solid ungranulated lysophosphatidylcholine with phospholipase A2 are provided. Also disclosed are methods for making a lipid matrix of lysophosphatidylcholine, monoglyceride and fatty acid, and lipid matrices of particular structure.
US08222232B2	Glucosamine and N-acetylglucosamine compositions and methods of making the same fungal biomass Glucosamine, N-acetylglucosamine and β-glucan compositions suitable for human or animal consumption or use are disclosed. The glucosamine, N-acetylglucosamine and β-glucan compositions are derived from fungal biomass containing chitin. Various methods of producing glucosamine, N-acetylglucosamine and β-glucan compositions are also disclosed.
US08222229B2	Peritoneal dialysis method A peritoneal dialysate containing adenosine triphosphate or a salt thereof, and a peritoneal dialysis method using the dialysate.The peritoneal dialysate is safe and causes less peritoneal injuries even when employed in peritoneal dialysis over a long period of time.
US08222227B2	RNAi-mediated inhibition of histamine receptor H1-related conditions RNA interference is provided for inhibition of histamine receptor H1 mRNA expression, in particular, for treating patients having an HRH1-related condition or at risk of developing an HRH1-related condition such as allergic conjunctivitis, ocular inflammation, dermatitis, rhinitis, asthma, or allergy.
US08222221B2	Modulation of gene expression through endogenous small RNA targeting of gene promoters Gene expression can be selectively regulated by endogenous miRNAs that target promoters of genes. Altering of the activity of these promoter-targeting miRNAs with single-stranded complementary oligonucleotides that bind the miRNA causes modulation of expression of the target gene. Endogenous miRNAs that modulate expression of target genes can be identified by (a) evaluating an endogenous miRNA for complementarity to a target gene promoter; and (b) determining that the complementary miRNA modulates expression of the target gene.
US08222214B2	Vaccine for the prevention of breast cancer relapse The invention features methods to induce and maintain a protective cytotoxic T-lymphocyte response to a peptide of the HER2/neu oncogene, E75, with the effect of inducing and maintaining protective or therapeutic immunity against breast cancer in a patient in clinical remission. The methods comprise administering to the patient an effective amount of a vaccine composition comprising a pharmaceutically acceptable carrier, an adjuvant such as recombinant human GM-CSF, and the E75 peptide at an optimized dose and schedule. The methods further comprise administering an annual or semi-annual booster vaccine dose due to declining E75-specific T cell immunity. The invention also features vaccine compositions for use in the methods.
US08222208B2	Methods for characterizing glycoproteins and generating antibodies for same The invention provides methods for preparing a peptide as an immunogen to generate an antibody specific for the deglycosylated form of a glycopolypeptide by preparing a peptide that includes an N-linked glycosylation site of said glycopolypeptide and identifying a peptide sequence that includes said glycosylated site and preparing said peptide wherein N of said site is converted to D.
US08222206B2	Method of enhancing the mobilization of hematopoietic stem cells using TAT-HOXB4H The present invention relates to a new and nonobvious method of producing the C-terminal histidine tagged TAT-HOXB4 fusion protein (TAT-HOXB4H), providing unexpected benefits of increased yield and stability to allow for in vivo administration of this protein, and pharmaceutical composition comprising an effective ingredient, TAT-HOXB4H, having stimulatory activity on the production of hematopoietic cells. More specifically, recombinant TAT-HOXB4H protein enhances engraftment of bone marrow transplants, hematopoietic reconstruction, bone marrow re-population and number of circulating stem cells, particularly after chemotherapy or irradiation.
US08222205B2	Process for solubilizing glucagon-like peptide 1 compounds Disclosed is a method of preparing a GLP-1 compound that is soluble in aqueous solution at pH 7.4 from a GLP-1 compound that is substantially insoluble in aqueous solution at pH 7.4. The insoluble GLP-1 compound is dissolved in aqueous base or in aqueous acid to form a GLP-1 solution. The GLP-1 solution is then neutralized to a pH at which substantially no amino acid racemization of the GLP-1 compounds occurs, after which the soluble GLP-1 compound is isolated from the neutralized solution.
US08222203B2	Macrocyclic oximyl hepatitis C serine protease inhibitors The present invention relates to compounds of Formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising a compound of the present invention.
US08222201B2	Crystalline form of linaclotide The present invention relates to crystalline forms of linaclotide, as well as to various methods and processes for the preparation and use of the crystalline forms.
US08222200B2	Organic compounds Tertiary non-vinylic carbamates of molecular weight less than 350 are useful as fragrance ingredients. A method of preparation is also described.
US08222198B2	Perfuming nitriles The present invention relates to methods of using certain unsaturated derivatives of 2,6,6-trimethyl-cyclohexane-1-acetonitrile as perfuming ingredients. These compounds are valuable patchouli odorants.
US08222195B2	Azeotropic compositions comprising fluorinated compounds for cleaning applications The present invention relates to compositions comprising fluorinated olefins or fluorinated ketones, and at least one alcohol, halocarbon, hydrofluorocarbon, or fluoroether and combinations thereof. In one embodiment, these compositions are azeotropic or azeotrope-like. In another embodiment, these compositions are useful in cleaning applications as a degreasing agent or defluxing agent for removing oils and/or other residues from a surface.
US08222193B2	Hydrogel particles The present invention relates to hydrogel particles containing bubbles and having a specific gravity of 0.7 to 1.00 and an average particle diameter of 50 to 500 μm, as well as a process for producing the same. The hydrogel particles may also contain hollow inorganic particles.
US08222192B2	Alcohol-based skin cleanser The invention provides a composition for cleansing skin comprising an emulsifiable organic solvent, such as ethanol or isopropyl alcohol, water, sodium benzoate, and a natural essential oil comprising a complex solution of compounds derived from a plant having topical antimicrobial activity. Natural essential oils useful as antimicrobials include tea tree, oregano, patchouli, rosemary, lemongrass, rose geranium, wild lavender, clove, lemon, eucalyptus, palmarosa, sandalwood, ravensara, and thyme. The cleanser may optionally include emollients, fragrances, thixotropic agents, chelating agents, antioxidants, and surfactants, such as glycerin, and propylene glycerol.
US08222191B2	Metal containing hydraulic compositions The present invention relates to a lubricating composition containing an oil of lubricating viscosity, a metal containing antiwear agent and a metal containing dispersant. The invention further provides for a method for lubricating a hydraulic system.
US08222190B2	Nano graphene-modified lubricant A lubricant composition having improved lubricant properties, comprising: (a) a lubricating fluid; and (b) nano graphene platelets (NGPs) dispersed in the fluid, wherein nano graphene platelets have a proportion of 0.001% to 60% by weight based on the total weight of the fluid and the graphene platelets combined. Preferably, the composition comprises at least a single-layer graphene sheet. Preferably, the lubricating fluid contains a petroleum oil or synthetic oil and a dispersant or surfactant. With the addition of a thickener or a desired amount of NGPs, the lubricant becomes a grease composition. Compared with graphite nano particle- or carbon nanotube-modified lubricants, NGP-modified lubricants have much better thermal conductivity, friction-reducing capability, anti-wear performance, and viscosity stability.
US08222185B2	Heat-sensitive transfer sheet and image forming method A heat-sensitive transfer sheet at least having a polyester support, a barrier layer, a heat-sensitive transfer layer containing a dye and a binder, both layers being applied on a surface of the support in this order, and having the heat-sensitive transfer layer including yellow, magenta, and cyan heat-sensitive transfer layers, and the yellow, magenta, and cyan heat-sensitive transfer layers and a protective layer being formed in area order, wherein the barrier layer contains a polyvinylpyrrolidone and cyan heat-sensitive transfer layer contains at least one silicone oil and at least one dye represented by the following formula (C1): wherein Ar represents a substituted or unsubstituted p-phenylene group; R1 represents a substituted or unsubstituted alkyl group; R2 represents a substituted or unsubstituted acylamino group, or a substituted or unsubstituted alkoxycarbonylamino group; R3 and R4 each independently represent a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkenyl group, or a substituted or unsubstituted aryl group.
US08222180B2	Adsorbent composition for removal of refractory sulphur compounds from refinery streams and process thereof The present invention relates to a adsorbent composition for removing refractory sulphur compounds from refinery streams comprising of base component in the range of 10 to 50 wt %, spinel oxide in the range of 20 to 60 wt % as a reactive metal oxide component and bimetallic alloy in the range of 10 to 40 wt % acting as an adsorption enhancer component, wherein the adsorption enhancer component acts in synergy with base component. The invention also relates to a process for the preparation of said composition by mixing in solid state fine particles of base component, spinel oxide and bimetallic alloy, homogenizing the mixture thus obtained with solvent, peptizing the wet solid with dilute mineral acid, extruding the peptized material with extrusion aiding agents, drying the extrudates, further calcining the dried extrudates and reducing the calcined material under hydrogen flow.
US08222166B2	High flux and low fouling filtration media Membranes suitable for microfiltration, ultrafiltration (UF) and nanofiltration (NF) filters are provided. Such membranes may include a nanofibrous scaffold, optionally in combination with a non-woven substrate and/or a coating of a polymer and a functionalized nanofiller. Suitable membranes may also include a coating of a polymer and a functionalized nanofiller on a substrate, which can include a non-woven membrane, a nanofibrous scaffold, or both.
US08222161B2	Substrate processing apparatus and semiconductor devices manufacturing method Substrate processing of a substrate is performed in a processing chamber and the evenness in in-plane film thickness is enhanced. An exhaust unit exhausts the atmosphere in the processing chamber and a processing gas is supplied that is excited by an exciting unit. A rotational drive unit horizontally rotates a support unit that supports a mounting substrate on which the substrate is mounted; and a coolant supply/discharge unit is connected to the lower end of the support unit through a connecting unit. The substrate mounting unit has a coolant circulation path therein. The support unit includes a first coolant flow path for passing coolant through the coolant circulation path. The coolant supply/discharge unit includes a second coolant flow path. The connecting unit connects the first coolant flow path and the second coolant flow path together and is provided outside the processing chamber.
US08222158B2	Electronic device, method of manufacturing the same, display and sensor A method of manufacturing an electronic device includes: preparing a film-attached substrate including a substrate, and an oxide semiconductor film containing In, Ga, and Zn and a metal film containing at least one of W or Mo provided in this order on the substrate; and wet-etching the metal film of the film-attached substrate using an etching liquid of which a main component is hydrogen peroxide under conditions such that an etching selection ratio between the metal film and the oxide semiconductor film (etching rate of the metal film/etching rate of the oxide semiconductor film) is 100 or higher.
US08222157B2	Hybrid RF capacitively and inductively coupled plasma source using multifrequency RF powers and methods of use thereof A device for inductively confining capacitively coupled RF plasma formed in a plasma processing apparatus. The apparatus includes an upper electrode and a lower electrode that is adapted to support a substrate and to generate the plasma between the substrate and the upper electrode. The device includes a dielectric support ring that concentrically surrounds the upper electrode and a plurality of coil units mounted on the dielectric support ring. Each coil unit includes a ferromagnetic core positioned along a radial direction of the dielectric support ring and at least one coil wound around each ferromagnetic core. The coil units generate, upon receiving RF power from an RF power source, electric and magnetic fields that reduce the number of charged particles of the plasma diffusing away from the plasma.
US08222149B2	Method for photoresist pattern removal The present disclosure provides a method for making a semiconductor device. The method includes forming a sacrificial layer on a substrate; forming a patterned resist layer on the sacrificial layer; performing an ion implantation to the substrate; applying a first wet etch solution to remove the patterned photoresist layer; and applying a second wet etch solution to remove the sacrificial layer.
US08222145B2	Method and composition for chemical mechanical planarization of a metal-containing substrate A composition and associated method for chemical mechanical planarization of a metal-containing substrate afford low dishing levels in the polished substrate while simultaneously affording high metal removal rates. Suitable metal-containing substrates include tungsten- and copper-containing substrates. Components in the composition include a silatrane compound, an abrasive, and, optionally, a strong oxidizing agent, such as a per-compound.
US08222144B2	Method for manufacturing semiconductor device, and polishing apparatus An interlayer insulating film is formed on a semiconductor substrate having a semiconductor element formed thereon. At this time, there are protrusions higher than surroundings thereof and non-protruding portions lower than the protrusions on the surface of the interlayer insulating film. First, a first polishing process is carried out on the surface of the interlayer insulating film with use of a first abrasive having non-Prestonian properties produced by mixing abrasive materials including abrasive grains, a polymer additive and water at a predetermined first mixture ratio. Then, after the first abrasive process shifts to an automatically stopping state, a second polishing process is carried out on the surface of the interlayer insulating film with use of a second abrasive having the concentration of polymer additive lower than that of the first abrasive and produced by mixing the abrasive materials at a second mixture ratio different from the first mixture ratio.
US08222143B2	Reworking method for integrated circuit devices A reworking method for integrated circuit devices includes the following: providing a substrate having a first base layer and a first dielectric layer formed thereon, performing a first dry etching process to remove the first dielectric layer, performing a CMP process to remove the first base layer, and sequentially reforming a second base layer and a second dielectric layer on the substrate. When certain layers on the IC device have hailed an inspection or when quality defects are found, the defective layer is removed according to the provided reworking method.
US08222141B2	Method for producing an organometallic layer A method for producing an organometallic layer includes providing a substrate having at least a layer with atoms of an oxidizable metal on its surface. The surface is exposed to a fluid that includes organic molecules having at least two functional groups that contain elements of main group VI such that the atoms of the oxidizable metal form a bond with the organic molecules. By consumption of the atoms of oxidizable metal and of the organic molecules, the organometallic layer is formed on the substrate at locations on the surface of the substrate where the atoms of oxizable are disposed, the atoms of oxizable metal being incorporated into the organometallic layer. A thickness of the organometallic layer is determined by a duration of the exposing, a thickness of the layer including the atoms of the oxidizable metal, and the number of organic molecules in the fluid.
US08222138B2	Method and structure of a thick metal layer using multiple deposition chambers A thick metal layer is formed on a semiconductor integrated circuit in multiple different deposition chambers. A first portion of the metal layer is formed in a first deposition chamber, the first thickness being approximately half the target thickness. The substrate is then removed from the first chamber and transported to a second chamber. The deposition of the same metal layer continues in a second chamber, having the same grain structure and orientation. The second portion of the metal layer is grown to achieve the final thickness. By using two different deposition chambers to form the single metal layer, layers in excess of 25,000 angstroms in thickness can be obtained.
US08222135B2	Increasing reliability of copper-based metallization structures in a microstructure device by using aluminum nitride By forming an aluminum nitride layer by a self-limiting process sequence, the interface characteristics of a copper-based metallization layer may be significantly enhanced while nevertheless maintaining the overall permittivity of the layer stack at a lower level.
US08222132B2	Fabricating high-K/metal gate devices in a gate last process The present disclosure provides a method that includes forming first and second gate structures over first and second regions, respectively, removing a first dummy gate and first dummy dielectric from the first gate structure thereby forming a first trench and removing a second dummy gate and second dummy dielectric from the second gate structure thereby forming a second trench, forming a gate layer to partially fill the first and second trenches, forming a material layer to fill the remainder of the first and second trenches, removing a portion of the material layer such that a remaining portion of the material layer protects a first portion of the gate layer located at a bottom portion of the first and second trenches, removing a second portion of the gate layer, removing the remaining portion of the material layer from the first and second trenches.
US08222131B2	Methods of forming an image sensor Provided is a method of forming an image sensor. The method may include providing a single crystalline semiconductor layer including at least one photodiode onto a support substrate; forming a material layer including dopants on the single crystalline semiconductor layer; and forming a dopant diffusion layer in the single crystalline semiconductor layer by diffusing the dopants of the material layer.
US08222129B2	Method for manufacturing solar cell A method for manufacturing a solar cell according to an exemplary embodiment includes: forming a first doping film on a substrate; patterning the first doping film so as to form a first doping film pattern and so as to expose a portion of the substrate; forming a diffusion prevention film on the first doping film pattern so as to cover the exposed portion of the substrate; etching the diffusion prevention film so as to form spacers on lateral surfaces of the first doping film pattern; forming a second doping film on the first doping film pattern so as to cover the spacer and exposed substrate; forming a first doping region on the substrate surface by diffusing an impurity from the first doping film pattern into the substrate; and forming a second doping region on the substrate surface by diffusing an impurity from the second doping film pattern into the substrate.
US08222128B2	Method for introducing impurities and apparatus for introducing impurities A method for introducing impurities includes a step for forming an amorphous layer at a surface of a semiconductor substrate, and a step for forming a shallow impurity-introducing layer at the semiconductor substrate which has been made amorphous, and an apparatus used therefore. Particularly, the step for forming the amorphous layer is a step for irradiating plasma to the surface of the semiconductor substrate, and the step for forming the shallow impurity-introducing layer is a step for introducing impurities into the surface which has been made amorphous.
US08222127B2	Methods of forming structures having nanotubes extending between opposing electrodes and structures including same A semiconductor structure including nanotubes forming an electrical connection between electrodes is disclosed. The semiconductor structure may include an open volume defined by a lower surface of an electrically insulative material and sidewalls of at least a portion of each of a dielectric material and opposing electrodes. The nanotubes may extend between the opposing electrodes, forming a physical and electrical connection therebetween. The nanotubes may be encapsulated within the open volume in the semiconductor structure. A semiconductor structure including nanotubes forming an electrical connection between source and drain regions is also disclosed. The semiconductor structure may include at least one semiconducting carbon nanotube electrically connected to a source and a drain, a dielectric material disposed over the at least one semiconducting carbon nanotube and a gate dielectric overlying a portion of the dielectric material. Methods of forming the semiconductor structures are also disclosed.
US08222122B2	Method of forming nonvolatile memory device Provided is a method of forming a nonvolatile memory device. The method may include alternatingly stacking n number of dielectric layers and n number of conductive layers on a substrate, forming a non-photosensitive pattern on the alternatingly stacked dielectric layers and conductive layers, etching the i-th conductive layer and i-th dielectric (2≦i≦n, i is a natural number indicating a stacking order of the conductive layers and the dielectric layers) by using the non-photosensitive pattern as an etch mask, laterally etching a sidewall of the non-photosensitive pattern and etching the i-th conductive layer, (i−1)-th conductive layer, i-th dielectric layer and (i−1)-th dielectric layer by using the etched non-photosensitive pattern as an etch mask.
US08222118B2	Wafer backside grinding with stress relief A method of relieving stress in a semiconductor wafer and providing a wafer backside surface finish capable of hiding cosmetic imperfections. Embodiments of the invention include creating a wafer backside surface which can be used for all dies on the semiconductor wafer intended for different product applications and be deposited with backside metallization (BSM) material. The method provides a rough texture on the wafer backside followed by isotropic etching of the wafer backside to recover the wafer strength as well as to preserve the rough texture of the wafer backside. After wafer backside metallization, the rough texture of the wafer backside hides cosmetic imperfections introduced by subsequent processes.
US08222116B2	Method for manufacturing semiconductor device The present invention provides a manufacturing technique of a semiconductor device and a display device using a peeling process, in which a transfer process can be conducted with a good state in which a shape and property of an element before peeling are kept. Further, the present invention provides a manufacturing technique of more highly reliable semiconductor devices and display devices with high yield without complicating the apparatus and the process for manufacturing. According to the present invention, an organic compound layer including a photocatalyst substance is formed over a first substrate having a light-transmitting property, an element layer is formed over the organic compound layer including a photocatalyst substance, the organic compound layer including a photocatalyst substance is irradiated with light which has passed through the first substrate, and the element layer is peeled from the first substrate.
US08222111B1	Simultaneous formation of a top oxide layer in a silicon-oxide-nitride-oxide-silicon (SONOS) transistor and a gate oxide in a metal oxide semiconductor (MOS) A method for semiconductor fabrication. The method includes providing a silicon substrate and forming a tunnel oxide layer over the silicon substrate. Thereafter, a nitride layer is formed over the tunnel oxide layer. The nitride layer and the tunnel oxide layer are etched except where at least one nonvolatile silicon oxide nitride oxide silicon (SONOS) transistor is formed. Additionally, oxide layers are simultaneously formed over the nitride layer corresponding to where at bast one SONOS memory transistor is formed and over the exposed silicon substrate corresponding to where at least one metal oxide semiconductor (MOS) transistor is formed.
US08222110B2	Method for fabricating semiconductor device with vertical transistor having a second active pillar formed over a first active pillar A method for fabricating a semiconductor device includes forming a plurality of first active pillars by etching a substrate using a hard mask layer as an etching barrier, forming a gate conductive layer surrounding sidewalls of the first active pillars and the hard mask layer, forming a word line conductive layer filling gaps defined by the gate conductive layer, forming word lines and vertical gates by simultaneously removing portions of the word line conductive layer and the gate conductive layer on the sidewalls of the hard mask layer, forming an inter-layer dielectric layer filling gaps formed by removing the word line conductive layer and the gate conductive layer, exposing surfaces of the first active pillars by removing the hard mask layer, and growing second active pillars over the first active pillars.
US08222108B2	Method of making a trench MOSFET having improved avalanche capability using three masks process A method of forming trench MOSFET structure having improved avalanche capability is disclosed. In a preferred embodiment according to the present invention, only three masks are needed in the fabricating process, wherein the source region is formed by performing source Ion Implantation through contact open region of a thick contact interlayer for saving source mask. Furthermore, said source region has a doping concentration along channel region lower than along contact trench region, and source junction depth along channel region shallower than along contact trench, and source doping profile along surface of epitaxial layer has Guassian-distribution from trenched source -body contact to channel region.
US08222105B2	Methods of fabricating a memory device A memory device comprising a vertical transistor includes a digit line that is directly coupled to the source regions of each memory cell. Because an electrical plug is not used to form a contact between the digit line and the source regions, a number of fabrication steps may be reduced and the possibility for manufacturing defects may also be reduced. In some embodiments, a memory device may include a vertical transistor having gate regions that are recessed from an upper portion of a silicon substrate. With the gate regions recessed from the silicon substrate, the gate regions are spaced further from the source/drain regions and, accordingly, cross capacitance between the gate regions and the source/drain regions may be reduced.
US08222102B2	Methods of forming field effect transistors, pluralities of field effect transistors, and DRAM circuitry comprising a plurality of individual memory cells A method of forming a field effect transistor includes forming trench isolation material within a semiconductor substrate and on opposing sides of a semiconductor material channel region along a length of the channel region. The trench isolation material is formed to comprise opposing insulative projections extending toward one another partially under the channel region along the channel length and with semiconductor material being received over the projections. The trench isolation material is etched to expose opposing sides of the semiconductor material along the channel length. The exposed opposing sides of the semiconductor material are etched along the channel length to form a channel fin projecting upwardly relative to the projections. A gate is formed over a top and opposing sides of the fin along the channel length. Other methods and structures are disclosed.
US08222101B2	Method of fabricating a MOS transistor having a gate insulation layer with a lateral portion and a vertical portion A MOS transistor suppressing a short channel effect includes a substrate, a first diffusion region and a second diffusion region separated from each other by a channel region in an upper portion of the substrate, a gate insulating layer including a first gate insulating layer disposed on a surface of the substrate in the channel region and a second gate insulating layer having a specified depth from the surface of the substrate to be disposed between the first diffusion region and the channel region, and a gate electrode disposed on the first gate insulating layer.
US08222100B2	CMOS circuit with low-k spacer and stress liner The present disclosure provides a method of forming a plurality of semiconductor devices, wherein low-k dielectric spacers and a stress inducing liner are applied to the semiconductor devices depending upon the pitch that separates the semiconductor devices. In one embodiment, a first plurality of first semiconductor devices and a second plurality of semiconductor devices is provided, in which each of the first semiconductor devices are separated by a first pitch and each of the second semiconductor devices are separated by a second pitch. The first pitch separating the first semiconductor devices is less than the second pitch separating the second semiconductor devices. A low-k dielectric spacer is formed adjacent to gate structures of the first semiconductor devices. A stress inducing liner is formed on the second semiconductor devices.
US08222095B2	Method for fabricating thin film transistor A method for fabricating a thin film transistor is provided. A gate is formed on a substrate. A gate insulating layer is formed on the substrate to cover the gate. A metal oxide material layer is formed on the gate insulating layer. A photoresist layer is formed on the metal oxide material layer, in which a thickness of the photoresist layer above the gate is larger than that of the photoresist layer above two sides adjacent to the gate. A portion of the metal oxide material layer is removed to form a metal oxide active layer by using the photoresist layer as a mask. The photoresist layer above the two sides adjacent to the gate is removed and the remaining photoresist layer covers a portion of the metal oxide active layer. A source and a drain are formed on the metal oxide active layer covered by the photoresist layer.
US08222091B2	Damascene method of making a nonvolatile memory device A method of making a device includes providing a first device level containing first semiconductor rails separated by first insulating features, forming a sacrificial layer over the first device level, patterning the sacrificial layer and the first semiconductor rails in the first device level to form a plurality of second rails extending in a second direction, wherein the plurality of second rails extend at least partially into the first device level and are separated from each other by rail shaped openings which extend at least partially into the first device level, forming second insulating features between the plurality of second rails, removing the sacrificial layer, and forming second semiconductor rails between the second insulating features in a second device level over the first device level. The first semiconductor rails extend in a first direction. The second semiconductor rails extend in the second direction different from the first direction.
US08222089B2	Tape for heat dissipating member, chip on film type semiconductor package including heat dissipating member, and electronic apparatus including the same Disclosed is a chip-on-film (COF) type semiconductor package and a device using the same. The COF type semiconductor package may include an insulation substrate including a top surface and bottom surface, a semiconductor device on the top surface of the insulation substrate, a heat dissipating component on the bottom surface of the insulation substrate, and at least one space between the bottom surface of the insulation substrate and a top surface of the heat dissipating component.
US08222087B2	Seed layer for a heat spreader in a magnetic recording head Magnetic recording heads and associated fabrication methods are disclosed. A heat spreader structure in a magnetic recording head includes a seed layer with a heat spreader layer formed on the seed layer. When the heat spreader layer (e.g., Aluminum Nitride) is grown on the seed layer (e.g., NiTa or Alumina), the heat spreader layer forms a well-oriented crystalline structure that allows for a desired thermal conductivity, such as a thermal conductivity greater than about 55 W/m−K. As a result of using the seed layer, a material such as Aluminum Nitride can be used for a heat spreader layer to effectively dissipate heat in a magnetic recording head.
US08222075B2	Nonvolatile semiconductor memory device using a variable resistance film and method of manufacturing the same A plurality of bit lines s arranged crossing a plurality of first word lines. A first diode is arranged at each cross point of the first word lines and the bit lines. A cathode of the first diode is connected to one of the first word lines. A first variable resistance film configuring the first diode is provided between the anodes of the first diodes and the bit lines, and configures a first memory cell together with each of the first diodes, and further, is used in common to the first diodes.
US08222061B2	Mist fabrication of quantum dot devices An example quantum dot (QD) device comprises a QD layer on a substrate, and may be fabricated by aerosol deposition, for example by mist deposition. An example approach includes providing a liquid precursor including QDs dispersed in a liquid carrier, generating a mist of droplets of the liquid precursor, directing the droplets towards the substrate so as to form a liquid precursor film on the substrate, and removing the liquid carrier from the liquid precursor film to form the quantum dot layer on the substrate. Example devices include multi-color QD-LED (light emitting diode) displays, and other devices.
US08222059B2	Method transparent member, optical device using transparent member and method of manufacturing optical device In a method of manufacturing an optical device, a whole substrate is first prepared which has a plurality of regions corresponding to substrates constituting a plurality of optical devices, respectively. A plurality of chips are then mounted to the plurality of regions, respectively. A whole sealing member having a plurality of sealing members is integrally attached to the whole substrate to form an intermediate body. The intermediate body is divided into the above-described regions. Thus, the optical device having a substrate, a chip as an optical element mounted to the substrate and a sealing member with transparency provided at the substrate for the purpose of sealing the chip is manufactured. This manufacturing method improves the efficiency of manufacturing an optical device.
US08222052B2	Method for growth of dilute-nitride materials using an isotope for enhancing the sensitivity of resonant nuclear reation analysis In certain desirable embodiments, the present invention relates to the use of 15N isotopes into GaAsN, InAsN or GaSbN films for ion beam analysis. A semiconductor-nitride assembly for growing and analyzing crystal growth in a group III-V semiconductor sample that includes: a substrate; a buffer layer deposited on the substrate, a nitrogen gas injector to incorporate enriched nitrogen gas and the nitrogen gas injector includes a concentration of enriched nitrogen gas, a thin film consisting of at least one group III element containing compound where at least one group III element is covalently bonded with the nitrogen in the presence of the same or different group V element of the buffer layer, and a proton beam to analyze the incorporation of the nitrogen gas in the thin film layer is described.
US08222050B2	Manufacturing method for semiconductor integrated device In a chip pick-up process after dicing in an assembly process during manufacture of a semiconductor integrated circuit device it is an important subject to diminish a pick-up defect caused by the reduction in thickness of each chip which is proceeding in quick tempo. Particularly, bending of the chip peripheral portion caused by a peeling operation is very likely to induce cracking and chipping of the chip. In the present invention, to solve these problems, in case of peeling a chip from a dicing tape (adhesive tape) or the like while vacuum-chucking the chip by a chucking collet, the flow rate of a vacuum chucking system in the chucking collet is monitored to check a bent state of the chip before complete separation of the first chip from the adhesive tape.
US08222046B2	Amplification for solid phase immunoassay The present invention is directed to immunoassays for detecting one or more target analytes in a fluid sample wherein the detection reaction occurs on a solid support and involves an amplification system. In particular, the invention is directed to making and using a test device having at least one site for detecting the presence of at least one target analyte, wherein a conjugate comprising dextran-polystreptavidin is immobilized at the test site(s) as a capture reagent for a complex containing the target analyze.
US08222043B2	Method for detecting a leak in flowing electrolyte batteries A leak detection system for a flowing electrolyte battery comprising a containment member associated with at least one of a stack of a flowing electrolyte battery and an electrolyte reservoir of a flowing electrolyte battery and a sensing member for sensing a fluid leak within the containment member.
US08222042B2	Interactive security screening system An interactive security screening system includes a main housing, a contact or palm pad provided on the main housing and a sample sheet positioned upon the contact pad. A sensor is operatively connected to the contact pad to measure pressure applied to the contact pad during a sample collection process. A feedback system, operatively connected to the contact pad and the sensor, provides the subject or screener with at least one of a visual signal and an audio signal to indicate whether requisite pressure was applied to the contact pad. A sample processing system analyzes the sample collection sheet through series, parallel or image processing to determine whether the trace residue sample contains a threat residue. The screening system also employs a spatial recognition system that focuses the sample processing system on particular portions of the sample collection sheet to increase overall system accuracy.
US08222041B2	Oxygen and carbon dioxide sensing A high electron mobility transistor (HEMT) capable of performing as a CO2 or O2 sensor is disclosed, hi one implementation, a polymer solar cell can be connected to the HEMT for use in an infrared detection system. In a second implementation, a selective recognition layer can be provided on a gate region of the HEMT. For carbon dioxide sensing, the selective recognition layer can be, in one example, PEI/starch. For oxygen sensing, the selective recognition layer can be, in one example, indium zinc oxide (IZO). In one application, the HEMTs can be used for the detection of carbon dioxide and oxygen in exhaled breath or blood.
US08222028B2	Plants modified with mini-chromosomes The invention is generally related to methods of generating plants transformed with novel autonomous mini-chromosomes. Mini-chromosomes with novel compositions and structures are used to transform plants cells which are in turn used to generate the plant. Methods for generating the plant include methods for delivering the mini-chromosome into plant cell to transform the cell, methods for selecting the transformed cell, and methods for isolating plants transformed with the mini-chromosome. Plants generated in the present invention contain novel genes introduced into their genome by integration into existing chromosomes.
US08222025B2	Multistory bioreaction system for enhancing photosynthesis The present invention relates to a multistory system for using waste carbon dioxide and waste heat to facilitate cultivation of photosynthetic organisms. In particular, the present invention relates to a multistory system with the incorporation of upconverting and downconverting luminescent materials and other components suitable for enhancing growth of photosynthetic organisms.
US08222022B2	Tri-functionalized cryptophane biosensors This invention relates to biosensors with improved solubility and affinity to a noble element. Specifically, the invention relates to methods and systems for the detection of target entities using the signal observed in a noble element complexed to the biosensor.
US08222021B2	System and process for treating waste gas employing bio-treatment technology A waste gas treatment process using biological treatment technology including filtering waste gas to be treated, and introducing the filtered waste gas into a biological treatment system periodically and switchably from two ends of the system.
US08222020B2	Biologically pure strain of Lactobacillus fermentum, strain Ess-1 A novel strain of Lactobacillus fermentum, denoted strain Ess-1, which has been deposited at Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH and has been assigned accession number DSM17851. Lactobacillus fermentum, strain Ess-1, has shown valuable properties in the inhibition of Candida, and has medical uses, in particular for the treatment and/or prevention of candidasis and urinary tract infections. In addition, pharmaceutical products and articles include the novel bacterial strain.
US08222018B2	Gordonia sihwensis strain and uses thereof Described herein is a strain of Gordonia sihwensis. The Gordonia sihwensis strain described herein may be used to sequester and/or biodegrade hydrocarbons. In particular, the Gordonia sihwensis strain described herein may be used in the remediation of drill cuttings coated with drilling fluid.
US08222017B2	Ketol-acid reductoisomerase using NADH Methods for the evolution of NADPH binding ketol-acid reductoisomerase enzymes to acquire NADH binding functionality are provided. Specific mutant ketol-acid reductoisomerase enzymes isolated from Pseudomonas that have undergone co-factor switching to bind NADH are described.
US08222016B2	Recombinant C-terminal α-amidating enzyme derivative Disclosed are: a recombinant C-terminal α-amidated enzyme derivative which lacks the formation of at least one disulfide bond among five disulfide bonds occurring in a C-terminal α-amidated enzyme derived from Xenopus laevis; DNA encoding the derivative; an expression vector carrying the DNA; a bacterium Escherichia coli transformed with the expression vector; and a method for producing the derivative by using the bacterium Escherichia coli.
US08222014B2	Planar electroporation apparatus and method An electroporation apparatus provides for the electroporation of adherent cells attached to an electrode surface or suspended cells in close proximity to an electrode surface. In one embodiment, the electrodes are transparent to allow cell viewing using a microscope or an automated image analysis machine. The geometry of the electrodes and associated electrically non-conductive structures may provide for well-defined regions of electroporated and non-electroporated adherent cells with a clearly defined interface between these regions, facilitating comparison of electroporated cells and non-electroporated cells, and evaluation of transfer of material from cell to cell via intercellular gap junctions.
US08222013B2	Bacteria and methods of use thereof A novel class of bacteria is described which has improved efficiency in the production of thanol by anaerobic fermentation of substrates containing carbon monoxide.
US08222012B2	Perhydrolase for enzymatic peracid production A process is provided for rapidly producing target concentrations of peroxycarboxylic acids from carboxylic acid esters. More specifically, carboxylic acid esters are reacted with a source of peroxygen, such as hydrogen peroxide, in the presence of an enzyme catalyst comprising an enzyme having identity to an acetyl xylan esterase from Lactococcus lactis having perhydrolysis activity. The polypeptide is an enzyme structurally classified as a member of the carbohydrate esterase family 7 (CE-7). The peroxycarboxylic acids produced by the present process can be used in disinfecting, bleaching, and other laundry care applications. Compositions comprising the reaction components and the peroxycarboxylic acids produced by the process are also provided.
US08222002B2	Human anti-amyloid beta peptide antibody and fragment of said antibody A human anti-amyloid β peptide (hereinafter referred to as “Aβ”) antibody that binds to Aβ to thereby inhibit aggregation of Aβ molecules, and a fragment of said antibody are provided. The antibody and a fragment thereof according to the present invention, comprising a variable region of a human-derived anti-Aβ antibody, strongly reacts with Aβ to thereby inhibit its aggregation and hence may be used as a medicament for the prophylaxis and treatment of Alzheimer dementia.
US08222001B2	Process for the culturing of cells The invention relates to a process for the culturing of cells, preferably E1-immortalized HER cells, more preferably PER.C6 cells in a reactor in suspension in a cell culture medium, wherein the cells produce a biological substance, preferably an antibody, wherein at least one cell culture medium component is fed to the cell culture and wherein the cell culture comprising the cells, the biological substance and cell culture medium is circulated over a separation system and wherein the separation system separates the biological substance from substances having a lower molecular weight than the biological substance and wherein the biological substance is retained in or fed back into the reactor. Preferably part of the substances of lower molecular weight is continuously removed from the cell culture.
US08221998B2	Expression of protein GB1 domain fusion proteins in mammalian cells This present invention relates to the use of the B1 domain of Protein G as an epitope tag for over-expression of proteins in mammalian cells.
US08221995B2	Methods and compositions for diagnosis and/or prognosis in systemic inflammatory response syndromes The present invention relates to methods and compositions for diagnosing SIRS, sepsis, severe sepsis, septic shock, or MODS in a subject, or assigning a prognostic risk for one or more clinical outcomes for a subject suffering from SIRS, sepsis, severe sepsis, septic shock, or MODS, the method comprising performing an immunoassay for CCL23 splice variant.
US08221984B2	Biomarkers for ovarian cancer The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying ovarian cancer status in a patient. In particular, it has been found that the biomarkers set forth in Table 1 are biomarkers for ovarian cancer. The biomarkers can be detected by SELDI mass spectrometry.
US08221981B2	Primers and probes for the amplification and detection of HIV Gag, Rev and Nef polynucleotides The invention relates to improved methods and compositions for the nucleic acid amplification of one or multiple variants (strains) of Human Immunodeficiency Virus (HIV) present in a sample, and preferably in a sample from a pathogen infected individual. In particular, novel primers, methods and kits for the amplification of one or more species of HIV Rev, Gag and Nef nucleic acids are provided. The amplified HIV nucleic acid can be used to identify and/or quantitate HIV variants present in a sample. Nucleic acids produced by the methods of the invention or the proteins encoded thereby can also be used directly as vaccines or to transfect/load antigen presenting cells. The loaded antigen presenting cells can be used as a vaccine for the treatment or prevention of HIV infection.
US08221970B2	Human papilloma virus probes for the diagnosis of cancer In one embodiment, the invention relates to a method of detecting cervical cancer, and other types of cancer, using a combination of at least three genomic clones, or fragments thereof, of high risk Human Papilloma Virus. For example, the invention relates to a composition comprising at least three full length genomic clones, or fragments thereof, of high risk Human Papilloma Viruses.
US08221969B2	Method of producing virus It is intended to provide a safe and efficient method of producing a virus which is free from animal-origin components in the whole process from culturing adhesive cells to producing the virus on an industrial scale by the cell culture. Namely, a method of producing a virus comprising: adhering adhesive cells to a support which has a polypeptide (P) having at least one cell-adhesive minimum amino acid sequence (X) per molecule, and is free from animal-origin components; culturing the adhesive cells in a medium free from animal-origin components; subculturing the cultured adhesive cells using a cell dispersing agent: free from animal-origin components; and then inoculating and proliferating a virus in the cells obtained by culturing the adhesive cells.
US08221967B2	Method for quantification of peptide and protein A determination method quantifies a specific protein or peptide contained in a trace amount with high accuracy and in a simple manner without the need of using any expensive reagent. A protein or peptide of interest can be quantified by LC/MS/MS by using, as an internal standard, a protein or peptide including an amino acid sequence having the reshuffling the binding order of amino acid residues in the amino acid sequence for the protein or peptide of interest.
US08221965B2	Antireflective coating compositions Antireflective coating compositions and related polymers are disclosed.
US08221962B2	Method of manufacturing electronic device A method of manufacturing an electronic device includes forming a photosensitive SOG oxide layer on a multi-layer ceramics substrate having a penetrating electrode, forming an opening by subjecting the photosensitive SOG oxide layer to an exposure treatment and developing treatment so that an upper face of the penetrating electrode is exposed, and forming a passive element on the photosensitive SOG oxide layer, the passive element being connected to the penetrating electrode through the opening.
US08221959B2	Lithographic printing plate precursor and method for preparation of lithographic printing plate A lithographic printing plate precursor comprising: an aluminum support having a hydrophilic surface; and a photosensitive layer comprising a binder polymer having an acid value of 0.3 meq/g or less, wherein the photosensitive layer comprises a pigment dispersed with a pigment dispersant which is free from a —COOH group, a —PO3H2 group and a —OPO3H2 group.
US08221955B2	Methods of producing ink toners and ink compositions including ink toners Methods of making ink toners for use in electrostatic imaging are disclosed.
US08221953B2	Emulsion aggregation process The present disclosure provides emulsion aggregation (EA) toner particles having less pigment on the particle surface and a more uniform pigment distribution. The process of preparing the toner includes specific mixing speeds and use of specific temperatures during the emulsion aggregation process and the addition of a shell to the toner particles.
US08221948B2	Toner compositions and processes Environmentally friendly toner particles are provided which may, in embodiments, include a bio-based amorphous polyester resin, optionally in combination with another amorphous resin and/or a crystalline resin. Toner particles may, in embodiments, have a core-shell configuration, with the shell formed of the bio-based amorphous polyester resin, the amorphous polyester resin, the crystalline polyester resin, or combinations thereof.
US08221941B2	Photomask blank manufacturing method and photomask manufacturing method A thin film made of a material containing a metal and silicon is formed on a light-transmissive substrate. Then, a treatment is performed to modify a main surface of the thin film in advance so that when exposure light having a wavelength of 200 nm or less is accumulatively irradiated on a thin film pattern of a photomask to be produced by patterning the thin film, the transfer characteristic of the thin film pattern does not change more than a predetermined degree. This treatment is performed by carrying out, for example, a heat treatment in an atmosphere containing oxygen at 450° C. to 900° C.
US08221940B2	Method and system for fracturing a pattern using charged particle beam lithography with multiple exposure passes In the field of semiconductor production using charged particle beam lithography, a method and system for fracturing or mask data preparation or proximity effect correction is disclosed, wherein a plurality of exposure passes are used, and where the sum of the base dosage levels for all of the exposure passes does not equal a normal dosage. Methods for manufacturing a reticle and manufacturing an integrated circuit are also disclosed, wherein a plurality of charged particle beam exposure passes are used, and where the sum of the base dosage levels for all of the exposure passes is different than a normal dosage.
US08221938B2	Method of making a stable hydrophilic coating/surface on carbon-based materials for fuel cell applications One exemplary embodiment includes a fuel cell component having comprising a carbon chain, and a material grafted to the coating/surface, wherein the material includes ionic or polar groups. One embodiment includes composite plates which include carbon that can be activated and treated to make their surface hydrophilic.
US08221936B2	Method and apparatus for attachment of fuel cell stack manifold A fuel cell system is provided which includes a mounting system for a manifold having a mounting plate. The fuel cell system also includes a fuel cell stack with a first end and a second end. The first end of the fuel cell stack includes at least one port in communication with the manifold. A clamping system is disposed on the second end of the fuel cell stack and is operable to engage the mounting plate of the manifold to couple the manifold to the fuel cell stack.
US08221932B2	Fuel cell A fuel cell 10 includes an MEA 200, an anode separator 100 and a cathode separator 300. The anode separator 100 forms alternate first and second flow channels 110 and 120. The first flow channel 110 is blocked in the middle. The second flow channel 120 is blocked in the both ends. The anode separator 300 forms alternate first and second flow channels 310 and 320. The first flow channel 310 is blocked in the middle. The second flow channel 320 is blocked in the both ends.
US08221931B2	Solid polymer electrolyte fuel cell stack A fuel gas inlet, a fuel gas outlet, an oxygen-containing gas inlet, an oxygen-containing gas outlet, and other components, which are disposed at upper and lower portions at both ends in the lateral direction, are provided in a first fuel cell stack. A plurality of cooling medium inlets, a plurality of cooling medium outlets, and other components are provided at lower portions on the long side and at upper portions on the long side respectively. A cooling medium flows from the lower portions to the upper portions through cooling medium flow passages to cool the power generation surface smoothly and reliably.
US08221930B2	Bipolar separators with improved fluid distribution A fuel cell separator having a first plate, the first plate including an active surface comprising a reactant flow field and a header fluidly connected thereto, an opposing non-active surface, and a header channel fluidly connected to the header, wherein the header further includes a recess directly fluidly connected to one end of the header channel, wherein the recess comprises a top perimeter and a side wall. In one embodiment, the header channel is formed on the active surface of the plate. In another embodiment, the header channel is formed on the non-active surface of the plate and the side wall of the header further comprises at least one fluid port fluidly connected to the end of the header channel.
US08221926B2	Fuel cell, method for operating fuel cell and fuel cell system A fuel cell, a method for operating a fuel cell and a fuel cell system, which ensure no dew condensation for a wet reaction gas in the inlet area of gas channels in plates in a fuel cell stack. Gas channels and heat medium channels are disposed on one surface and the other surface of one plate, respectively. Gas channels are disposed on the other plate such that they face the gas channels in the plate. A gas inlet header is disposed at the upper part of the gas channel in the plate and a heat medium inlet header is disposed at the upper part of the heat medium channels such that they face the gas inlet header on the other side. Cooling water such as heat medium is supplied from the heat medium supply manifold hole to the heat medium inlet header, thereby warming up the same.
US08221921B2	Non-aqueous electrolyte battery A non-aqueous electrolyte battery has a cathode, an anode, an electrolyte, and a separator. The separator is a microporous resin film of a single layer made of a resin material in which at least one kind of insulating and flame-retarding fiber is dispersed in a polyolefin resin.
US08221920B2	Separator for valve regulated lead-acid battery and valve regulated lead-acid battery A separator for a valve regulated lead-acid battery which comprises a paper sheet where very fine glass fiber is a main component, which has a piercing strength (puncture strength) of 4.5 N/mm or more and a tensile strength of 7.0 N/10 mm2 or more. The paper sheet is made by blending 80 to 90% by weight of glass fiber having 1.5 μm or less average fiber size, 5 to 10% by weight of single-material monofilament-form thermally non-adhesive organic fiber (non-heat-bondable organic fiber) and 5 to 10% by weight of single-material monofilament-form thermally adhesive organic fiber (heat-bondable organic fiber) comprising the same kind of material as in the thermally non-adhesive organic fiber in a wet papermaking process whereupon the fiber materials are bonded each other by thermal fusion of the thermally adhesive organic fiber whereby a coat (film) by melting of the organic fiber is not substantially formed on the surface of the glass fiber.
US08221917B2	Positive active material composition for rechargeable battery, electrode including the same, and rechargeable battery including the same A positive active material composition for a rechargeable battery, a positive electrode including the same, and a rechargeable battery including the same, the positive active material composition including a positive active material and a surface-modified metal oxide.
US08221916B2	Method for manufacturing lithium ion secondary battery A method for manufacturing a lithium ion secondary battery comprises the step of sintering a laminate sandwiched by setters disposed on both sides of the laminate having only interfaces between an electrolyte green sheet and a positive electrode green sheet and/or a negative electrode green sheet. A lithium ion secondary battery manufactured by the method described above is also provided.
US08221915B2	High performance lithium or lithium ion cell Disclosed herein are lithium or lithium-ion batteries that employ an aluminum or aluminum alloy current collector protected by conductive coating in combination with electrolyte containing aluminum corrosion inhibitor and a fluorinated lithium imide or methide electrolyte which exhibit surprisingly long cycle life at high temperature.
US08221907B2	Chrysene derivative and organic electroluminescent device using the same A chrysene derivative shown by the following formula: wherein R1 to R10 and R21 to R25 are independently a hydrogen atom, a substituted or unsubstituted alkyl group having 1 to 10 carbon atoms, a substituted or unsubstituted cycloalkyl group having 3 to 10 ring carbon atoms, a substituted or unsubstituted alkylsilyl group having 3 to 20 carbon atoms, a substituted or unsubstituted arylsilyl group having 8 to 30 carbon atoms, or a substituted or unsubstituted aryl group having 6 to 20 ring carbon atoms, provided that at least one of R21 to R25 is a substituted or unsubstituted fused aromatic ring group having 10 to 20 ring carbon atoms or a substituted or unsubstituted fluorenyl group.
US08221906B2	Electroluminescent polymers for electronic applications The present invention relates to novel polymers comprising a repeating unit(s) of the formula (I) wherein at least one of the substituents R1, R2, R3, R4, R5, R6, and R7 is a group -(Sp)x1-HEI, wherein Sp is a spacer unit, HE1 is a group (HE1I), which increases the hole-injection and/or hole-transport properties of the polymers; or a group (HE1II), which increases the electron-injection and/or electron-transport properties of the polymers, or a group (HE1III), which increases the hole-injection and/or hole-transport properties of the polymers and the electron-injection and/or electron-transport properties of the polymers, x1 is 0, or 1, and their use in electronic devices. The polymers according to the invention have excellent solubility in organic solvents and excellent film-forming properties. In addition, high charge carrier mobilities and high temperature stability of the emission color can be observed, if the polymers according to the invention are used in polymer light emitting diodes (PLEDs).
US08221905B2	Carbazole-containing materials in phosphorescent light emitting diodes Carbazole-containing compounds are provided. In particular, the compounds are oligocarbazole-containing compounds having an unsymmetrical structure. The compounds may be useful in organic light emitting devices, in particular as hosts in the emissive layer of such devices.
US08221898B2	Multi-layered composite part made of steel having optimized paint adhesion A multilayered composite part includes a plurality of steel alloy layers connected to one another, with at least one core layer consisting of a soft, well deformable steel alloy and at least one steel alloy layer of a very high strength steel alloy, arranged on the core layer. A multilayered composite part which is characterized simultaneously by a high strength paired with very good outer skin quality and very good paint adherence, is achieved in that at least one outer steel alloy layer of a soft, well deformable steel alloy is provided on the very high strength steel alloy layer.
US08221897B2	Rolled copper foil A rolled copper foil according to the present invention includes a crystal grain alignment wherein: when normalized intensity of {200}Cu plane diffraction of a copper crystal in results obtained by an X-ray diffraction pole figure measurement with respect to a rolled surface is plotted against at different values of angle α, the normalized intensity being obtained during a β scanning in the pole figure measurement, a ratio of a maximum value A of the normalized intensity with angle α in a range of 40° to 60° to a maximum value B of the normalized intensity with angle α in a range of 80° to 90° is equal to or greater than 4; and when the normalized intensity increases with increasing angle α in a range of 25° to 45°, there is essentially no area in which the normalized intensity increases stepwise.
US08221892B2	Rubber-reinforced resin, anti-static resin composition, molded article and laminate The objective of the present invention is to provide a rubber-reinforced resin which, when formed into a molded article, can prevent contamination or soiling of an article contacted with the molded article or a device on the periphery of the molded article and is excellent in impact resistance and transparency, and an anti-static resin composition which is excellent in impact resistance and anti-static properties. The present rubber-reinforced resin comprises a rubber-reinforced copolymeric resin produced by polymerization of 20 to 95 parts by mass of monomer components comprising methyl methacrylate, an aromatic vinyl compound and a cyanidated vinyl compound in the presence of a rubbery polymer having a predetermined volume-average particle diameter, or comprises a mixture of the rubber-reinforced copolymeric resin and a copolymer of the above-mentioned monomer components. Additionally, the present anti-static resin composition comprises the above-mentioned rubber-reinforced resin and a polymer type anti-static agent, wherein the rubbery polymer is contained in an amount from 5% to 40% by mass. In each of the rubber-reinforced resin and the anti-static resin composition, the total amount of substances detected at a retention time of 10 to 24 minutes is 20,000 μg or less per gram of the sample as determined by pyrolysis GC analysis.
US08221885B2	Thermally conductive polymer compositions having low thermal expansion characteristics An injection moldable, thermally conductive polymer composition that has ultra low CTE properties is provided. The composition is suitable both for substrate applications in high precision electronics assemblies as well as over molding applications in conjunction with ceramic substrates. The composition includes a base polymer matrix material loaded with thermally conductive filler, which imparts thermal conductivity to the polymer matrix while also maintaining or enhancing the dielectric properties of the base polymer. The resultant composition exhibits CTE properties in the range of between 9 ppm/° C. and 2 ppm/° C., exhibits an optical anisotropy of below 1.5, and a thermal conductivity of greater than 2 W/m° K. The composition is suitable for use in over molding applications in conjunction with virtually any suitable electronics substrate material without the introduction of mechanical stresses produced by large CTE differentials.
US08221883B2	Graphite sheet and manufacturing method of the same For a graphite sheet, a peak intensity ratio (P100/002) of a (100) diffraction peak and a (002) diffraction peak by X-ray diffractometry, and a peak intensity ratio (P110/002) of a (110) diffraction peak and a (002) diffraction peak thereby are set at 10 or more. The graphite sheet is manufactured through a step of preparing a polymer liquid which contains a polymer having carbon in its molecular chains and develops optical anisotropy, a step of unidirectionally orienting the molecular chains of the polymer, a step of obtaining a compact from the polymer liquid in the state that the orientation of the molecular chains of the polymer is maintained, and a step of carbonizing and thereafter graphitizing the compact.
US08221882B2	Process and apparatus for producing inorganic spheres A process for producing inorganic spheres, which comprises injecting an aqueous liquid containing an inorganic compound into a laminar flow of an organic liquid which runs at a flow rate of from 0.001 to 2 m/s in a flow path through a porous membrane to form a W/O type emulsion and solidifying the aqueous liquid containing an inorganic compound in the W/O type emulsion.
US08221868B2	Finished product structure formed by in-mold decoration process A finished product structure formed by In-mold decoration process includes an electromagnetic protective material, a bearing layer and a formed plastic material. The electromagnetic protective material includes a metal film, a structure reinforced layer and an electromagnetic isolation layer. The structure reinforced layer is located between the metal film and electromagnetic isolation layer to enhance physical strength of the electromagnetic protective material. The bearing layer includes an adhesive surface laid with an adhesive layer and a bearing surface. The adhesive surface faces the electromagnetic protective material. The electromagnetic protective material and bearing layer are disposed in a mold, and plastic material is injected onto the bearing surface through a plastic material runner to form the formed plastic material. The formed plastic material includes a first surface bonded to the bearing surface and a second surface on another side opposite to the first surface.
US08221866B2	Ionomer and article therewith A carpet cushion has attached thereto or thereon a layer of polymer composition comprising, consisting essentially of, consisting of, or produced from a fatty acid-modified ionomer and optionally blended or coextruded with an ethylene-containing polymer wherein the ionomer comprises, consists essentially of, consists of, or is produced from an ethylene copolymer and a fatty acid.
US08221862B2	Polyphenylene sulfide resin composition, process for producing the same, and molded article A polyphenylene sulfide resin composition including 100 parts by weight of a resin composition that consists of 99 to 60 wt % of a polyphenylene sulfide resin (a), and 1 to 40 wt % of at least one type of noncrystalline resin (b) selected from the group consisting of polyetherimide resin and polyether sulfone resin and 0.1 to 10 parts by weight of a compound (c) containing at least one group selected from epoxy group, amino group and isocyanate group, wherein the non-crystalline resin (b) forms an island phase and the number-average dispersed particle size of the noncrystalline resin (b) is 1,000 nm or less.
US08221861B2	Earguard sealing system II: single-chamber systems Single-chamber coatings are provided. The single-chamber coating includes a first medium, a second medium, and a ridge structure. The first medium covers at least a first portion of the second medium so as to form a chamber. At least one material property of the first medium is different than the second medium. The first medium forms a first wall of the chamber. The first wall is configured to apply a restorative force upon deformation of the chamber. The ridge structure is along a second wall of the chamber and is configured to direct the second medium substantially parallel to a ridge structure plane when the chamber is deformed. The chamber forms at least a portion of a coating. The coating is configured to be attached to an object that is configured to be inserted into an orifice.
US08221858B2	Three-dimensional parts having porous protective structures Three-dimensional parts having porous protective structures built with powder-based additive manufacturing systems, the porous protective structures being configured to protect the three-dimensional parts from damage during de-powdering processes.
US08221856B2	Synthetic grass structure An elastic underlayer for floorings, for instance, floorings for sports facilities such as synthetic-grass coverings, comprises a first laminar structure and a second laminar structure that enclose between them pouches filled with granular elastic material. The structures in question comprise a layer of non-woven fabric coupled with a polyolefin layer. The polyolefin layers enclose between them the pouches, which preferably have a parallelepiped shape with a square base, with sides having a length of 20-60 mm, typically 45 mm, and a height of between 20 and 40 mm, typically 30 mm. The pouches are filled with granular elastic material, such as granules of recycled tires having a size of between 0.5 and 7.0 mm.
US08221853B2	Microwave plasma CVD of NANO structured tin/carbon composites A method for forming a graphitic tin-carbon composite at low temperatures is described. The method involves using microwave radiation to produce a neutral gas plasma in a reactor cell. At least one organo tin precursor material in the reactor cell forms a tin-carbon film on a supporting substrate disposed in the cell under influence of the plasma. The three dimensional carbon matrix material with embedded tin nanoparticles can be used as an electrode in lithium-ion batteries.
US08221852B2	Methods of atomic layer deposition using titanium-based precursors Methods of forming titanium-containing films by atomic layer deposition are provided. The methods comprise delivering at least one precursor to a substrate, wherein the at least one precursor corresponds in structure to Formula I: wherein: R is C1-C6-alkyl; n is zero, 1, 2, 3, 4 or 5; L is C1-C6-alkoxy or amino, wherein the amino is optionally independently substituted 1 or 2 times with C1-C6-alkyl.
US08221851B2	Process and device for treating the coating of thermoplastic resin containers A process and device for drying the coating of containers made of thermoplastic material. The process involves feeding said containers through a furnace divided into two areas: in the first, most of the solvent of the coating is removed by heating the paint with infrared lamps, while the temperature of the containers is controlled through an airflow; in the second, the remaining solvent is removed using said airflow coming from the first area of the furnace.
US08221849B2	Process for producing self-sealing pneumatic tire and apparatus therefor A process in which a self-sealing pneumatic tire consisting of a pneumatic tire after vulcanization molding furnished with a sealant layer being uniform without thickness irregularity and a cover sheet layer therefore is produced without the use of an organic solvent and expensive apparatus; and an apparatus therefore. The process is characterized by sequentially performing the operations of injecting a viscous sealant material onto the internal surface of a pneumatic tire (T) after vulcanization molding; diffusing the sealant material into a sheet form by centrifugal force while rotating the pneumatic tire (T) around the tire axis to thereby form a sealant layer (11); injecting a cover material of uncured rubber material or resin material onto the inside surface of the sealant layer (11); diffusing the cover material into a sheet form by centrifugal force while rotating the pneumatic tire (T) around the tire axis to thereby form a cover sheet layer (12); and irradiating the cover sheet layer (12) with electron beams, infrared rays, ultraviolet rays or ultrasonic waves to thereby harden the same.
US08221845B2	Cellulose resin film and method for producing the same There is provided a method for producing a cellulose resin film, with which the deterioration of the entire film and the occurrence of die lines can be prevented. The method for producing a cellulose resin film, including the steps of: discharging two cellulose resins A and B molten in the respective extruders in the form of an A/B/A three-layer sheet from a die upon a support by co-extrusion; and cooling and solidifying the sheet-shaped molten resin into a film, wherein the resin A, which forms a pair of outer layers of the A/B/A three-layer sheet, has a number average molecular weight smaller than that of the resin B, which forms the inner layer of the A/B/A three-layer sheet, and the resin A has a number average molecular weight of 20,000 or more and 50,000 or less, and the resin B has a number average molecular weight of 30,000 or more and 100,000 or less.
US08221844B2	Wallpaper for use in an automobile and a method for making same An automobile wallpaper, and an exterior surface finishing agent for the door trim, seats, and so on, of automobiles, as well as its manufacturing method. To manufacture such automobile wallpaper, a printing process is performed on the surface of a surface material which is currently being used, in order to render a three-dimensional effect to the surface, so as to achieve various luxurious appearances. The three-dimensional effect of the printing is maintained even during the molding process, and it also possesses excellent properties relative to sound absorbency, due to the three-dimensional effect of the surface.
US08221843B2	Methods and compositions for coating interior components of motor vehicles and interior components of motor vehicles coated using same A coating composition for coating at least one contact surface of a component is disclosed as well as methods of coating the component with the coating composition. The component may be, for example, an interior trim part for interiors of motor vehicles. The contact surface contacts at least one other component and on which relative movement occurs. The coating may be a wear-resistant and/or a low-friction coating. The coating may be formed on the component from a paint composition and a hardener composition. When the coating is dry, the coating may have a dried layer thickness of between about 25 micrometers and about 100 micrometers.
US08221842B2	Metallic laminate and method for preparing the same The present invention provides a metallic laminate and a method for preparing the same. The metallic laminate includes a metal layer, and at least one polyimide resin layer. The polyimide resin layer has a modulus of elasticity of 70 Mpa at 400° C.
US08221833B2	Window with anti-bacterial and/or anti-fungal feature and method of making same Certain example embodiments of this invention relate to a window having anti-fungal/anti-bacterial properties and/or self-cleaning properties, and a method of making the same. In certain example embodiments, a silver based layer is be provided and the layer(s) located thereover (e.g., the zirconium oxide inclusive layer) are designed to permit silver particles to migrate/diffuse to the surface over time to kill bacteria/germs at the surface of the coated article thereby creating an anti-bacterial/anti-fungal effect. In certain example embodiments, silver may also or instead be mixed in with other material as the top layer of the anti-bacterial coating.
US08221832B2	Method of making heat treated coated article having carbon layer and utilizing removable zinc oxide inclusive protective film A method of making a heat treated (HT) coated article to be used in shower door applications, window applications, or any other suitable applications where transparent coated articles are desired. For example, certain embodiments of this invention relate to a method of making a coated article including a step of heat treating a glass substrate coated with at least a layer of or including carbon and an overlying protective film including a zinc oxide inclusive layer. Following and/or during heat treatment (e.g., thermal tempering, or the like) the protective film may be removed. Other embodiments of this invention relate to the pre-HT coated article, or the post-HT coated article.
US08221830B2	Method of manufacturing cellulose electrode for fuel cells, cellulose electrode manufactured thereby, and use of cellulose fibers as fuel cell electrodes Disclosed is a novel cellulose electrode having high performance, which is capable of substituting for carbon paper used as a conventional fuel cell electrode. A method of manufacturing the cellulose electrode includes cutting cellulose fibers to a predetermined length and binding the fibers, or directly weaving the fibers, thus producing a cellulose sheet, directly growing carbon nanotubes on the cellulose sheet, and supporting a platinum nano-catalyst on the surface of the carbon nanotubes using chemical vapor deposition. An electrode including the cellulose fibers and use of cellulose fibers as fuel cell electrodes are also provided. As a novel functional material for fuel cell electrodes, porous cellulose fibers having micropores are used, thereby reducing electrode manufacturing costs and improving electrode performance.
US08221829B2	Preparation of prussian blue coating film for electrochromic device The present invention relates to a method for preparing a Prussian blue coating film for an electrochromic device, more particularly to a method for preparing a Prussian blue coating film for an electrochromic device comprising an electrochromic layer coated on a light transmitting substrate including a coating of a transparent electrode, an ion storage layer coated on another light transmitting substrate including a coating of a transparent electrode and an electrolyte layer formed between the electrochromic layer and the ion storage layer, wherein the ion storage layer is formed with a specific nano-dispersed composition comprising Prussian blue by wet coating, thereby providing comparable or better physical properties, including light transmittance, response time, durability, etc., when compared with the conventional electrochemical techniques, simplifying the manufacturing processes and significantly improving the productivity. With improved economic advantages, the present invention enables the realization of large-sized electrochromic devices.
US08221827B2	Patterning method A patterning method according to an embodiment of the present invention comprises: acquiring information about a surface state of an underlying film formed on a substrate; determining, based on the surface state, whether irregularity/foreign matter is present in each shot region in which a pattern is to be formed; and solidifying a resist agent while a first template, when it is determined that no irregularity/foreign matter is present in the shot region, or a second template that is different from the first template, when it is determined that irregularity/foreign matter is present in the shot region, is brought close to the underlying film on the shot region at a certain distance with the resist agent therebetween.
US08221825B2	Comprehensive method for local application and local repair of thermal barrier coatings A method for the local initial application of a thermal barrier coating layer (3), or for the local repair of coating defects and/or deteriorations of components (1) in the hot gas path of a gas turbine engine, which components are coated with a thermal barrier coating layer, includes at least the following steps: (I) in the case of repair, normally overall inspection of the whole component (1) for the determination of the location of defect/deterioration, as well as of corresponding type of defect/deterioration of each place for a multitude of locations of the component (1); (II) if needed, preparation of the surface in at least one location; (III) local application of a ceramic tissue together with a wet chemical thermal barrier coating layer deposition material for the formation of a patch (5) of ceramic matrix composite; (IV)a intermediate inspection of the patch and/or the surface; (IV)b in the case of a repetitive and/or multi-step repair method, subsequent layer application of a ceramic tissue together with a wet chemical thermal barrier coating layer deposition material for the formation of a patch (5) of ceramic matrix composite at this location; (V) if needed, surface finishing at the at least one location; and (VI) final inspection of the at least one location. Steps (IV)a, (V) and (VI) can be omitted with the provision that at least one of steps (IV)a or (VI) is carried out.
US08221823B2	Method for fabricating material A diamond-like carbon film (DLC film) is formed on the surface of a base material made of an inorganic material, such as ceramics, or the like, or an organic material, such as resin, or the like. The surface of the resultant DLC film is treated with plasma, or the like, so as to be activated. Various monomers having biocompatibility, etc., are graft-polymerized to the activated surface of the DLC film, whereby a polymer layer is formed from the monomers grafted to the surface of the DLC film. Thus, the base material coated with the DLC film modified with a polymer which does not readily separate can be realized.
US08221820B2	Frozen food products, emulsifying systems, and related methods The present invention relates to frozen food products, such as ice creams, having special emulsifying systems. The emulsifying system preferably contains mono esters of propane-1,2-diol and fatty acids, such as 2-PGME, and it may furthermore contain additional emulsifiers such as 1-PGME and/or diglycerides. The frozen food products are characterised by improved organoleptic and sensory properties as well as reduced rate of melting. The invention furthermore relates to the emulsifying systems as such as well as methods of preparing the frozen food product.
US08221819B2	Fatty acid desaturases from primula The invention relates generally to methods and compositions concerning desaturase enzymes that modulate the number and location of double bonds in long chain poly-unsaturated fatty acids (LC-PUFA's). In particular, the invention relates to methods and compositions for improving omega-3 fatty acid profiles in plant products and parts using desaturase enzymes and nucleic acids encoding for such enzymes. In particular embodiments, the desaturase enzymes are Primula Δ6-desaturases. Also provided are improved soybean oil compositions having SDA and a beneficial overall content of omega-3 fatty acids relative to omega-6 fatty acids.
US08221811B2	Liquid flow control and beverage preparation apparatuses, methods and systems Apparatuses, methods and systems for liquid flow control and beverage preparation are disclosed. The apparatuses, methods and systems of the present invention include liquid flow control and beverage preparation capsules, pods, cartridges, pouches, systems, and modules for controlling and directing flow streams of liquid through a beverage preparation process. The apparatuses, methods and systems of the present invention may be used in combination with or included as an integral assembly of any apparatus, method or system for liquid dispension.
US08221807B2	Use of stevensite for mycotoxin adsorption Applicants have amended the original Application, as filed, to include the appropriate arrangement of the specification, with titles for the appropriate sections, as suggested by the Examiner on pages 3 and 4 of the Advisory Action. No new subject matter is introduced by any of these amendments.
US08221806B2	Methods of using pomegranate extracts for causing regression in lesions due to arteriosclerosis in humans Methods of using pomegranate extracts of the present invention for treating patients with atherosclerosis, or increased intima-media thickness of an artery, are provided. The methods comprise the step of administering to the patient a composition comprising a therapeutically effective amount of an extract from pomegranate. The methods of the present invention may also be used to decrease the incidence of stroke or heart attack in a patient.
US08221805B2	Compositions for alleviating inflammation and oxidative stress in a mammal An antioxidant-promoting composition that increases antioxidant defense potential in a subject is disclosed comprising Bacopa monniera extract; milk thistle extract, ashwagandha powder, green tea extract, Gotu kola powder, Ginko biloba leaf extract; Aloe vera powder; turmeric extract; and N-acetyl cysteine. The antioxidant-promoting composition of the invention safely induces cellular antioxidant potential to achieve an overall net decrease in oxidative stress without the undesirable side-effects associated with the individual components of the antioxidant-promoting composition. Also disclosed is a method for reducing the undesirable side-effects of free radicals in a subject by administering to a subject in need of such antioxidants an effective amount of antioxidant-promoting composition of the invention.
US08221804B2	Compositions and methods for enhancing cognitive function The invention encompasses novel compositions containing a methylation modifying compound isolated from botanical raw materials, including a fruit of the genus Coffea, and microbial raw materials, methods of making such compositions, and methods of treating or preventing human disease using such compositions. The methylation modifying compound in botanical extracts of the present invention can dramatically increase the level of methylation of PP2A, thus increasing cognitive function, particularly in persons suffering from or prone to developing Alzheimer's disease.
US08221798B1	Pharmaceutical and method for treatment of chronic rhinosinusitis A method and solution for treating nasal infections efficiently is provided. The method includes providing a first solution comprising 0.1 to 2 wt % sodium chloride and providing a second solution comprising 2 to 8 wt % NaOCl. A first aliquot of the first solution and a second aliquot of the second solution are mixed to provide a therapeutic solution comprising at least 3-600 ppm free chlorine. The therapeutic solution is introduced into a sinus cavity containing an infection.
US08221797B2	Wood preserving composition for treatment of in-service poles, posts, piling, cross-ties and other wooded structures This invention discloses a wood preservative composition for the supplemental or remedial treatment of in-service poles, posts, piling, cross ties and other wooden structures. The wood preservative composition comprises copper 8-hydroxyquinolate (oxine copper) in combination with a boron compound or a fluoride compound.
US08221796B2	Copper-based fungicide/bactericide The present invention discloses an improved copper-based fungicide/bactericide composition. The improved composition offers higher biological activity over typical copper-based products, while requiring significantly less copper in the composition. The present invention also discloses methods of making the improved copper-based fungicide/bactericide composition. The present invention further discloses methods of using the improved copper-based fungicide/bactericide composition.
US08221791B1	Silica-based antibacterial and antifungal nanoformulation A silica-based nanoformulation and method is used to treat citrus canker, inhibit the growth of mold and mildew, and add nutrients to soil used for agricultural purposes. The nanotechnology-enabled copper-loaded, silica nanoformulation (CuSiNP/NG) design is a “revolutionary re-invention” of Cu for safe application because it provides a formulation with maximum abundance of ionic Cu, provides sustained and optimal Cu ion release for long-term disease protection, better adherence to plant surfaces and structural surfaces due to gel-based nanostructure of CuSiNG, thus avoiding multiple spray applications and reducing the amount of Cu used in comparison to existing Cu compounds without compromising antibacterial activity. Thus, the silica-based nanoformulation releases copper in non-toxic quantities to the environment and the silica matrix provides an environmentally safe host material with a flexible design that is optimized to provide specific antifungal and antibacterial remediation using infrequent applications.
US08221790B2	Therapeutic polyesters and polyamides Polymers (i.e. polyesters, polyamides, and polythioesters or a mixture thereof) which degrade hydrolytically into biologically active compounds are provided. Methods of producing these polymers, intermediates useful for preparing these polymers, and methods of using these polymers to deliver biologically active compounds to a host are also provided.
US08221788B2	Pharmaceutical compositions containing rosuvastatin calcium A pharmaceutical composition is disclosed containing amorphous rosuvastatin calcium and at least one of the following stabilizing agents: magnesium hydroxide, calcium acetate, calcium gluconate, calcium glycerophosphate, or aluminum hydroxide, together with at least one pharmaceutically acceptable excipient.
US08221786B2	Pharmaceutical formulations containing an SGLT2 inhibitor Pharmaceutical formulations are provided which are in the form of capsules or tablets for oral use and which include a medicament dapagliflozin or its propylene glycol hydrate and a pharmaceutical acceptable carrier therefor, which formulation is designed for immediate release.
US08221784B2	Transdermal hormone delivery system: compositions and methods A transdermal hormone delivery system (THDS) is disclosed. The THDS is useful for control of fertility and as therapy for a variety of diseases and conditions treatable by robust delivery of progestin and estrogen hormones, particularly the progestin, levonorgestrel. The THDS comprises a backing layer, an adjoining adhesive polymer matrix comprising an effective amount of at least a progestin hormone, delivery of which is enhanced by one or more skin permeation enhancing agents present in pre-determined amounts. The THDS is capable of providing effective daily doses of progestin and estrogen hormones from a small surface area in contact with the skin, e.g., less than 20 square centimeters. Methods of fertility control and various types of hormone replacement therapy utilizing the THDS are also disclosed.
US08221781B2	Osteoinductive bone material Osteogenic bone implant compositions that approximate the chemical composition of natural bone are provided. The organic component of these implant compositions is osteoinductive despite the presence of the inorganic component and, further, is present in an amount sufficient to maximize the regenerative capabilities of the implant without compromising its formability and mechanical strength. The composition may be an osteoinductive powder, including demineralized bone matrix (DBM) particles, a calcium phosphate powder, and, optionally, a biocompatible cohesiveness agent. The powder may be combined with a physiologically-acceptable fluid to produce a formable, osteoinductive paste that self-hardens to form a poorly crystalline apatitic (PCA) calcium phosphate having significant compressive strength. The bone implant materials retain their cohesiveness when introduced at an implant site and are remodeled into bone in vivo. Methods for using these implant materials to repair damaged bone and a method of assaying the content of DBM particles, by weight, in a bone implant material are also provided.
US08221779B2	Compositions and methods for the delivery of poorly water soluble drugs and methods of treatment The present embodiment of the invention is generally directed to compositions comprising suspensions of poorly water-soluble compounds recrystallized in nanoparticulate sizes ranging from 0.1 to 5 μm. In addition, the embodiment of the invention is directed to methods for preparation and administration of these compositions to a patient for prevention and treatment of disease states. In particular, the embodiment of the invention is directed to compositions comprising suspensions of poorly water-soluble compounds, such as antimitotics and antibiotics, in nanoparticulates and methods of prevention and treatment of chronic disease states, such as cancer, by intraperitoneal and intravenous administration of such compositions.
US08221778B2	Drug-containing implants and methods of use thereof The present invention provides implants comprising a therapeutic drug and a polymer containing polylactic acid (PLA) and optionally polyglycolic acid (PGA). The present invention also provides methods of maintaining a therapeutic level of a drug in a subject, releasing a therapeutic drug at a substantially linear rate, and treating schizophrenia and other diseases and disorders, utilizing implants of the present invention.
US08221775B2	Pyrrolin-2-ylamino compounds for combating animal pests The present invention relates to pyrrolin-2-ylamino compounds for combating animal pests. The invention also relates to a method for controlling animal pests by using these compounds, to plant propagation material and to an agricultural composition comprising said compounds. The invention also relates to a method for treating or protecting an animal from infestation or infection by parasites by using said compounds: wherein: A is a radical of the formulae A.1 or A.2: n, m, R1, R2, R3, R4, R5a, R5b, R5c, R5d, R5e, and R5f are defined herein.
US08221771B2	Formulations containing an immune response modifier Pharmaceutical formulations in an aqueous (preferably, sprayable) formulation including an immune response modifier (IRM), such as those chosen from imidazoquinoline amines, tetrahydroimidazoquinoline amines, imidazopyridine amines, 6,7-fused cycloalkylimidazopyridine amines, 1,2-bridged imidazoquinoline amines, imidazonaphthyridine amines, imidazotetrahydronaphthyridine amines, oxazoloquinoline amines, thiazoloquinoline amines, oxazolopyridine amines, thiazolopyridine amines, oxazolonaphthyridine amines, thiazolonaphthyridine amines, and 1H-imidazo dimers fused to pyridine amines, quinoline amines, tetrahydroquinoline amines, naphthyridine amines, or tetrahydronaphthyridine amines, are provided. In one embodiment, the aqueous formulations are advantageous for treatment and/or prevention of allergic rhinitis, viral infections, sinusitis, and asthma.
US08221769B2	Microorganisms for therapy Therapeutic methods and microorganisms therefor are provided. The microorganisms are designed to accumulate in immunoprivileged tissues and cells, such as in tumors and other proliferating tissue and in inflamed tissues, compared to other tissues, cells and organs, so that they exhibit relatively low toxicity to host organisms. The microorganisms also are designed or modified to result in leaky cell membranes of cells in which they accumulate, resulting in production of antibodies reactive against proteins and other cellular products and also permitting exploitation of proferating proliferating tissues, particularly tumors, to produce selected proteins and other products. Vaccines containing the microorganisms are provided. Combinations of the microorganisms and anti-cancer agents and uses thereof for treating cancer also are provided.
US08221768B2	Chimeric flavivirus immunogens comprising the Japanese encephalitis virus (JEV) prM signal sequence The present invention encompasses isolated nucleic acids containing transcriptional units which encode a signal sequence of one flavivirus and an immunogenic flavivirus antigen of a second flavivirus or of a chimeric immunogenic flavivirus antigen comprising sequence from more than one flavivirus. The invention further encompasses a nucleic acid and protein vaccine and the use of the vaccine to immunize a subject against flavivirus infection. The invention also provides antigens encoded by nucleic acids of the invention, antibodies elicited in response to the antigens and use of the antigens and/or antibodies in detecting flavivirus or diagnosing flavivirus infection.
US08221767B2	Antigenicity of infectious pancreatic necrosis virus VP2 sub-viral particles expressed in yeast Infectious pancreatic necrosis virus (IPNV), the etiologic agent of infectious pancreatic necrosis in salmonid fish, causes significant losses to the aquaculture industry. The gene for the viral capsid protein (VP2) was cloned into a yeast expression vector and expressed in Saccharomyces cerevisae. Expression of the capsid gene in yeast resulted in formation of approximately 20 nanometer sub-viral particles composed solely of VP2 protein. Anti-IPNV antibodies were detected in rainbow trout vaccinated either by injection of purified VP2-subviral particles (rVP2-SVP) or by feeding recombinant yeast expressing rVP2-SVP. Challenge of rVP2-SVP immunized trout with a heterologous IPNV strain and subsequent viral load determination showed that both injection and orally vaccinated fish had lower IPNV loads than naive or sham-vaccinated fish. This study demonstrates the ability of rVP2-SVPs to induce a specific immune response and the ability of immunized fish to reduce the viral load after an experimentally induced IPNV infection. The invention is not limited to IPNV, and is applicable to other similar viruses for which SVPs can be made and administered to fish.
US08221764B2	Secreted campylobacter flagella coregulated proteins as immunogens The invention relates to an immunogenic composition composed of secreted polypeptides derived from Campylobacter jejuni non-flagellar proteins that are coordinately expressed with the flagellar regulon. The invention also relates to a method of inducing an immune response to the non-flagellar protein polypeptides.
US08221759B2	Neutralizing monoclonal antibodies to respiratory syncytial virus The present invention relates to the identification and cloning of a novel neutralizing human monoclonal antibody to the Respiratory Syncytial Virus. The invention provides such antibodies, fragments of such antibodies retaining RSV-binding ability, chimeric antibodies retaining RSV-binding ability, and pharmaceutical compositions including such antibodies. The invention further provides for isolated nucleic acids encoding the antibodies of the invention and host cells transformed therewith. Finally, the invention provides for diagnostic and therapeutic methods employing the antibodies and nucleic acids of the invention.
US08221754B2	Antihuman α9 integrin antibody and use of the same The present invention relates to: an antibody, particularly a monoclonal antibody, a chimeric antibody, a humanized antibody and a human antibody, which specifically recognize human α9 integrin; a hybridoma cell which produces the monoclonal antibody; a method for producing the monoclonal antibody; a method for producing the hybridoma cell; a therapeutic agent comprising the anti-human α9 integrin antibody; a diagnostic agent comprising the human α9 integrin antibody; and a method for screening a compound which inhibits the activity of human α9 integrin.
US08221753B2	Endoglin antibodies The present application relates to compositions of humanized and humanized/deimmunized anti-endoglin antibodies and antigen-binding fragments thereof. One aspect relates to antibodies having one or more modifications in at least one amino acid residue of at least one of the framework regions of the variable heavy chain, the variable light chain or both. Another aspect relates to antibodies which bind endoglin and inhibit angiogenesis. Another aspect relates to the deimmunization of humanized antibodies to reduce immunogenicity. Another aspect relates to the use of humanized and humanized/deimmunized antibodies which bind endoglin for the detection, diagnosis or treatment of a disease or condition associated with endoglin, angiogenesis or a combination thereof.
US08221751B2	Tumor-targeting monoclonal antibodies to FZD10 and uses thereof The present invention relates to an antibody or a fragment thereof which is capable of binding to a Frizzled homologue 10 (FZD10) protein, such as a mouse monoclonal antibody, a chimeric antibody and a humanized antibody. Also, the present invention relates to a method for treating and/or preventing FZD10-associated disease; a method for diagnosis or prognosis of FZD10-associated disease; and a method for in vivo imaging of FZD10 in a subject.
US08221749B2	Antibodies directed to angiopoietin-1 and angiopoietin-2 and uses thereof Disclosed are specific binding agents, such as fully human antibodies, that bind to angiopoietin 1 and/or angiopoietin-2. Also disclosed are heavy chain fragments, light chain fragments, and CDRs of the antibodies, as well as methods of making and using the antibodies.
US08221747B2	Stable pancreatic enzyme compositions Compositions of the present invention, comprising at least one digestive enzyme (e.g., pancrelipase) are useful for treating or preventing disorders associated with digestive enzyme deficiencies. The compositions of the present invention can comprise a plurality of coated particles, each of which is comprised of a core coated with an enteric coating comprising at least one enteric polymer and 4-10% of at least one alkalinizing agent, or have moisture contents of about 3% or less, water activities of about 0.6 or less, or exhibit a loss of activity of no more than about 15% after six months of accelerated stability testing.
US08221742B2	Methods of making and using Lactobacillus strains Lactobacillus strains that have a genetic Profile I based on Apa I, Not I, and Xba I digests are provided. Preferably, the strains decrease level of at least one of coliforms and E. coli within the gastrointestinal tract of an animal. A direct-fed microbial that includes the strain is additionally provided. A method of feeding an animal the strain and a method of forming a direct fed microbial that includes the strain is also provided.
US08221738B2	Method for enhanced uptake of viral vectors in the myocardium The present invention relates to improved therapies for the treatment of heart disease, particularly the improved delivery of therapeutic agents to heart tissue by direct infusion into the coronary circulation. A preferred embodiment of the invention is a method of treating or preventing a cardiovascular disease by transfecting cardiac cells of a large mammal, the method comprising, identifying a mammal in need of treatment or prevention of heart disease, supplying NO to the coronary circulation prior to, and/or during the infusion of a therapeutic polynucleotide into a blood vessel of the coronary circulation in vivo, where the therapeutic polynucleotide is infused into the blood vessel over a period of at least about three minutes, where the coronary circulation is not isolated or substantially isolated from the systemic circulation of the mammal; and where the therapeutic polynucleotide transfects cardiac cells of the animal resulting in the treatment or prevention of the heart disease.
US08221737B2	Hepatitis C virus inhibitors The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit RNA-containing virus, particularly the hepatitis C virus (HCV). Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
US08221735B2	Embolic compositions Embolic compositions comprising macromers having a backbone comprising a polymeric backbone comprising units with a 1,2-diol or 1,3-diol structure, such as polyvinyl alcohol, and pendant chains bearing crosslinkable groups and, optionally, other modifiers. When crosslinked, the macromers form hydrogels having many properties advantageous for use as embolic agents to block and fill lumens and spaces. The embolic compositions can be used as liquid embolic agents and crosslinked in situ or as preformed embolic articles, such as microspheres.
US08221734B2	Self-heating shaving compositions Non-pressurized shaving compositions are described that provide a warm/hot sensation during use as the result of an exothermic redox reaction. The compositions are post-foaming via nascent gas release in situ due to the generation of carbon dioxide. The carbon dioxide induced foam is maintained for several minutes after the compositions are dispensed, whereby the compositions are capable of providing both a warm sensation and sustained lather, a balance which heretofore has been a significant challenge.
US08221732B2	Continuous moisturization compositions An aqueous hair moisturizing composition is provided. The composition includes a cationic component, an oil containing about 70 percent or greater unsaturated fatty acids with chain length of C18 or greater, a phytosterol and a cellulosic polymer. Also provided is a method of imparting extended moisturization to the hair including the steps of applying to the hair in need of extended moisturization a composition including a cationic component, an oil containing about 70 percent or greater unsaturated fatty acids with chain length of C18 or greater, a phytosterol and a cellulosic polymer, and retaining the composition in contact with the hair for a time sufficient to impart extended moisturization to the hair.
US08221724B2	Mild oral care compositions Oral compositions comprising fused silica, wherein the composition is essentially free of sodium lauryl sulfate.
US08221722B2	Antibacterial oral care compositions with fused silica An oral care composition comprising a fused silica abrasive and an active.
US08221720B2	Purification methods The invention relates to novel processes for the purification of radiolabelled tracers, using a solid-support bound scavenger group. The general concept being illustrated by the scheme:
US08221714B2	Method for the preparation of titanium nitride powder Nano-sized titanium nitride powder can be prepared by a simple process comprising subjecting mixed powder of titanium trichloride and lithium nitride to high-energy ball milling using a plurality of balls in an airtight reactor vessel under an inert gas atmosphere to form composite powder, and recovering the titanium nitride powder therefrom.
US08221713B2	Method for making metal titanate A method for making a mono-dispersed metal titanate includes the steps of: (a) mixing titanate ester, metal salt, and rare earth metal salt in a molar ratio of 1:1:x in a reaction medium comprised of ethanol and water to form a solution, wherein x is in the range from 0 to 0.1; (b) heating the solution, under an alkaline condition to form a white sediment; (c) filtering out liquid part of the solution to obtain the white sediment, (d) washing the white sediment, and (e) drying the white sediment to obtain mono-dispersed metal titanate.
US08221712B2	Absorption medium for the selective removal of hydrogen sulfide from fluid streams An absorption medium for the removal of acid gases from a fluid stream comprises an aqueous solution a) of at least one amine and b) at least one phosphonic acid, wherein the molar ratio of b) to a) is in the range from 0.0005 to 1.0. The phosphonic acid is, e.g., 1-hydroxyethane-1,1-diphosphonic acid. The absorption medium exhibits a reduced regeneration energy requirement compared with absorption media based on amines or amine/promoter combinations, without significantly decreasing the absorption capacity of the solution for acid gases.
US08221709B2	Hardwood lignosulfonates for separating gangue materials from metallic sulfide ores Disclosed are compositions and methods for separating gangue material from metallic sulfide ores. The compositions typically include a lignosolfonate and do not include a cyanide salt. Suitable lignosulfonates may include lignosulfonates, for example hardwood lignosulfonate having a weight average molecular weight of about 3 kDa to about 12 kDa and having a relatively low sulfur content and a relatively low sulfonate content.
US08221704B2	Microfluidic device and microfluidic system with the same Provided is a microfluidic device and microfluidic system with the device. The microfluidic device includes a substrate; a channel formed in the substrate and in which a fluid can move; a valve controlling flow of a fluid flowing along the channel and including a phase transition material which can be melted by energy such as electromagnetic wave energy; and a lens disposed on the substrate and adjusting an irradiating region of the valve, onto which the energy is applied.
US08221703B2	Device for collecting sample Disclosed herein is a device for collecting a sample, which is intended to dispense a received sample onto a measurement strip. The device includes a main body and a pair of receiving pieces. The receiving pieces protrude from a first end of the main body in such a way as to be spaced apart from each other while facing each other, and receive the sample by capillary force acting on a space which is defined between the receiving pieces and which is open on right, left and bottom sides. The device allows the received sample to be easily transferred to a reaction zone of a measurement strip, and enables the sample to be completely absorbed by the reaction zone because of capillary force in a receiving area when the device comes into contact with the reaction zone of the strip.
US08221700B2	Structures for controlling light interaction with microfluidic devices Systems and methods for improved measurement of absorbance/transmission through fluidic systems are described. Specifically, in one set of embodiments, optical elements are fabricated on one side of a transparent fluidic device opposite a series of fluidic channels. The optical elements may guide incident light passing through the device such that most of the light is dispersed away from specific areas of the device, such as intervening portions between the fluidic channels. By decreasing the amount of light incident upon these intervening portions, the amount of noise in the detection signal can be decreased when using certain optical detection systems. In some embodiments, the optical elements comprise triangular grooves formed on or in a surface of the device. The draft angle of the triangular grooves may be chosen such that incident light normal to the surface of the device is redirected at an angle dependent upon the indices of refraction of the external medium (e.g., air) and the device material. Advantageously, certain optical elements described herein may be fabricated along with the fluidic channels of the device in one step, thereby reducing the costs of fabrication. Furthermore, in some cases the optical elements do not require alignment with a detector and, therefore, facilitate assembly and/or use by an end user.
US08221699B2	Sample applicators for analytical assays A liquid applicator for applying a liquid sample to a liquid receiving surface is disclosed. The liquid applicator comprises a bibulous line to hold a first predetermined volume of liquid for application to a liquid receiving surface. A second predetermined volume less than or equal to the first predetermined volume is applied to the liquid receiving surface in a substantially uniform and consistent pattern. Systems and methods for using embodiments of the liquid applicators are also disclosed.
US08221696B2	Detergent dispensing device A detergent dispensing device for an automatic washing machine has a cartridge, a selecting mechanism, an operating mechanism, and a thermal element. The cartridge includes a plurality of chambers to accommodate a detergent composition. The selecting mechanism selectively exposes each chamber to wash liquor allowing the detergent, in use, to be washed out of the chamber. The operating mechanism is movable from a first position to a second position for loading mechanical energy into the device which provides a restoring force for the operating mechanism. The thermal element retains the operating means in the second position and is arranged to move when subjected to an elevated temperature prevailing in an interior of the washing machine during a wash cycle, thereby the thermal element moves or releases the operating mechanism. The operating mechanism is arranged to advance the selecting mechanism to an adjacent chamber as the cartridge remains stationary.
US08221688B2	Exhaust gas purification device for internal combustion engine An exhaust gas purification device for an internal combustion engine is provided in an exhaust passage of the internal combustion engine. The exhaust gas purification device includes an HC trapping converter comprising a carrier; an HC adsorbing layer, supported on the carrier and adapted to adsorb unburned fuel; and a ternary catalyst layer, supported on a surface of the HC adsorbing layer and adapted to oxidize and remove the unburned fuel. The HC adsorbing layer includes particulate HC adsorbents each of which has a follow space and which are stacked. The ternary catalyst layer covers the HC absorbing layer such that a thickness of the ternary catalyst layer increases from an upstream side to a downstream side of the converter in the direction of exhaust gas flow.
US08221687B2	System and method for the removal of greenhouse gases A system and a method are provided for removing greenhouse gases, particulates and pollutants from the atmosphere utilizing a greenhouse gas collection apparatus. An atmospheric mixture is collected and progressively treated in first, second and third tube furnaces and a scrubber to produce an effluent for treatment in a chemical processing plant. The first tube furnace oxidizes hydrocarbons, the second tube furnace oxidizes any remaining nitrous and nitric oxides, and the third tube furnace oxidizes sulfur dioxide. The scrubber precipitates carbon dioxide as calcium carbonate. A vacuum pump draws the atmospheric mixture through tube furnaces and the scrubber.
US08221685B2	Small volume in vitro sensor and methods of making A sensor utilizing a non-leachable or diffusible redox mediator is described. The sensor includes a sample chamber to hold a sample in electrolytic contact with a working electrode, and in at least some instances, the sensor also contains a non-leachable or a diffusible second electron transfer agent. The sensor and/or the methods used produce a sensor signal in response to the analyte that can be distinguished from a background signal caused by the mediator. The invention can be used to determine the concentration of a biomolecule, such as glucose or lactate, in a biological fluid, such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. An enzyme capable of catalyzing the electrooxidation or electroreduction of the biomolecule is typically provided as a second electron transfer agent.
US08221682B2	System for incubating the contents of a reaction receptacle An automated analyzer for performing multiple diagnostic assays includes multiple modules in which aspects of the assay are performed on fluid samples contained in reaction receptacles. The analyzer includes stations for automatically preparing a sample, pre-heating the sample, incubating the sample, performing an analyte isolation procedure, and ascertaining the presence of a target analyte. A receptacle transporting system moves reaction receptacles from one station to the next. A method for performing an assay includes an automated process for isolating and amplifying a target analyte. The process is performed by moving each of a plurality of reaction receptacles containing a solid support material and a fluid sample between stations for pre-heating and incubating the contents of the reaction receptacle and for separating the target analyte bound to the solid support from the fluid sample. An amplification reagent is added to the analyte after the separation step and before incubation.
US08221678B2	System and process for removing or treating harmful biological and organic substances within an enclosure A system and process is provided for removing or treating harmful biologic and organic substances within an enclosure, such as a container, building or vehicle. Air within the enclosure is heated to a predetermined temperature to kill organisms and cause harmful substances in the structure to migrate into the ambient air. Boric acid in combination with the heat may be used to kill mold and similar undesirable organisms. Temperature and pressure levels are monitored. The heated air carrying the harmful substances is passed through a filter to remove the harmful substances, and the heated air is re-circulated to enhance efficiency. The system effectively kills insects, molds, viruses and bacteria and reduces the levels of allergens and volatile organic compounds in the structure.
US08221671B2	Imager and method for consistent repeatable alignment in a solid imaging apparatus A solid imaging apparatus is provided that includes a replaceable cartridge containing a source of build material and an extendable and retractable flexible transport film for transporting the build material layer-by-layer from the cartridge to the surface of a build in an image plane. An operator using the device needs merely to remove a spent cartridge and replace it with a fresh cartridge to continue solid imaging virtually uninterrupted. The apparatus also includes the capability of withdrawing and inserting an imager without the operator having to perform a separate alignment step. A brush attached to the transport film and forming part of the cartridge provides for intra-layer removal of excess uncured build material. If desired, the apparatus can produce a fully reacted build. A high intensity UV source cures the build between layers. An injection molded build pad is designed to hold a build in an inverted position for improving the build. The invention also provides for tilting the build elevator to reduce air entrainment and for releasing the build from the image plane.
US08221670B2	Mold motion control system for an injection molding machine A method for injection molding comprises pre-positioning a clamp piston within a cylinder housing to a datum position axially intermediate a clamping position and an unclamped position, the clamp piston affixed to a tie bar, the clamp piston and cylinder housing cooperating to provide a clamp chamber and an unclamp chamber in a clamp cylinder housing on axially opposite sides of the clamp piston for urging the clamp piston towards the clamping and unclamped positions, respectively, when pressurized. Pre-positioning the clamp piston can include leaving a positioning gap between portions of a mold before releasably locking a tie bar to one of the moving or stationary platens, and then advancing the moving platen to substantially close the positioning gap after the releasable locking has been completed. Pre-positioning the clamp piston can include moving a stop member to an advanced position in the cylinder housing, and urging the clamp piston to bear against the stop member before the releasable locking step has been completed.
US08221669B2	Method for building three-dimensional models in extrusion-based digital manufacturing systems using ribbon filaments A consumable material for use in an extrusion-based digital manufacturing system, the consumable material comprising a length and a cross-sectional profile of at least a portion of the length that is axially asymmetric. The cross-sectional profile is configured to provide a response time with a non-cylindrical liquefier of the extrusion-based digital manufacturing system that is faster than a response time achievable with a cylindrical filament in a cylindrical liquefier for a same thermally limited, maximum volumetric flow rate.
US08221668B2	Process for forming plastic, apparatuses for forming plastic, and articles made therefrom Process and apparatus for forming plastics by heating an open mold and contacting the open mold with plastic particulate material to form a melted skin on the mold, and resulting articles made therefrom. Single skin molded articles may be multi-layered with or without paint on the surface. Multiple skin molded articles may be made by complementary male and female molds, brought together after the skins are made on the individual male and female molds, and may include sandwiched layers of plastic filler or expandable foam filled centers, with or without various inserts or reinforcements. Multi-layer composite articles are made with inserts and/or reinforcements that may be embedded in and surrounded by expandable foam plastic, if used as a middle layer. Resulting articles include a pick-up truck bed box, an industrial tabletop, a series of modular housing panels, an airplane cockpit door, and material handling pallets, among others.
US08221666B2	Composite structure and method for producing a composite structure A method for producing a composite structure and a composite structure obtained by the method is described. The method comprises the following steps: a) providing a mold comprising a rigid mold part and a flexible vacuum bag, b) placing a fiber insertion in the mold part, the fiber insertion including a plurality of fiber layers and, when placed in the mold part, having an upper surface and a lower surface as well as a first side and a second side, the fiber insertion including a first zone at the first side and a second zone at the second side, the first zone and the second zone being separated by an intermediate zone, c) placing an upper distribution medium above the intermediate zone of the fiber insertion, the distribution medium comprising a resin distribution network for distributing resin along the upper distribution medium, d) placing a number of resin inlet channels above the upper distribution medium for supplying liquid resin to the resin distribution network, e) placing a first vacuum outlet at least partially overlapping the first zone of the fiber insertion and a second outlet at least partially overlapping the second zone of the fiber insertion, f) placing the vacuum bag on top of the mold part, thus sealing the vacuum bag against the mold part to define a mold cavity, g) evacuating the mold cavity, h) connecting a source of uncured fluid resin to the resin inlet channels so as to feed uncured resin to the resin distribution network in order to fill the mold cavity and to impregnate at least the fiber insertion and the upper distribution medium with uncured resin, and i) allowing the resin to cure in order to form the composite structure.
US08221650B2	AL2O3-SiO2-based oxide phosphor An oxide phosphor that is highly durable and produces visible light when excited by exposure to near-ultraviolet excitation light, comprising an oxide having the composition represented by the formula (Al2O3)x.(SiO2)1-x, where 0
US08221647B2	Oxygen-absorbing composition An oxygen-absorbing composition for use as a component of a plastic packaging material that includes in relatively sufficient proportions iron, acidifier, and electrolyte.
US08221639B2	Surface treatment methods for implants made of titanium or titanium alloy A method of producing a generally uniformly roughened surface on Ti 6/4 alloy or titanium for contact with living bone comprises exposing the Ti 6/4 alloy or titanium in an aqueous solution of citric acid and hydrofluoric acid for a suitable time period to remove the native oxide from the Ti 6/4 alloy or titanium so as to expose the Ti 6/4 or titanium metal surface and create the desired surface topography.
US08221630B2	Process for dewatering a hydraulic fluid The present invention provides a method and a device for dewatering a hydraulic fluid of a hydraulic system, in particular in the aerospace sector, comprising a container which has a sorbent, a feed which supplies the hydraulic fluid from the hydraulic system to the container for the hydraulic fluid to be passed through the sorbent such that it can be dewatered in a dewatering mode of the device, and a return which returns the dewatered hydraulic fluid from the container to the hydraulic system in the dewatering mode of the device. The hydraulic fluid can be dewatered continuously and very efficiently by the method and the device according to the invention.
US08221627B2	Nitrification and denitrification of digested biosolids Processes and apparatus are provided for the nitrification and denitrification of digested biosolids. The rate of nitrification/denitrification is controlled by sensing the amount of oxygen or another parameter in the digested biosolids and adjusting the amount of oxygen supplied to the biosolids, such as through automated adjustment of an aeration device. To promote nitrification, the amount of oxygen available in the digested biosolids is increased. To promote denitrification, the amount of oxygen available in the digested biosolids is decreased. The processes and apparatus are well suited for reducing the concentration of ammonium in biosolids or off-gas resulting from aerobic thermophilic digestion of wastewater sludges. The processes and apparatus are well suited for reducing the dosage of chemicals required for dewatering operations of biosolids.
US08221626B2	Renewable energy microgeneration system A renewable energy microgeneration system is disclosed. The system includes a portable processing container with a mixing tank for mixing waste with a liquid, a macerating pump in fluid communication with the mixing tank that is configured to macerate the waste into smaller pieces, a plurality of small holding tanks in fluid communication with the mixing tank that are configured to perform at least one of a pasteurization thermophilic anaerobic digestion on the waste, a large holding tank in fluid communication with the plurality of small holding tanks that is configured to perform mesophilic anaerobic digestion on the waste after at least one of a pasteurization thermophilic anaerobic digestion is performed on the waste, and a de-watering unit in fluid communication with the large holding tank that is configured to dry what remains of the waste after mesophilic anaerobic digestion is performed on the waste; a controller for automating the flow of the waste between the mixing tank, the plurality of small holding tanks, the large holding tank, and the de-watering unit such that a user does not need to complete any tasks for performing mesophilic anaerobic digestion after the waste is loaded into the mixing tank; and a portable gas storage container comprising a gas storage tank that is configured to store biogas generated by the mesophilic anaerobic digestion, wherein the portable processing container and the portable gas storage container are configured to be transported to a site and placed in fluid communication with each other so the gas storage tank can store biogas generated by mesophilic anaerobic digestion in the processing container at the site.
US08221625B2	Process for producing polyolefin resin composition and filter device for use in this process The filter device 10 according to the present invention is a device for filtering a polyolefin resin composition containing a polyolefin ingredient, wherein the device comprises a main body 10a having a flow passage 10b, a sintered metal filter 13 having a filtration accuracy of 1 to 100 μm, a wire netting 14a having a line diameter of 0.01 to 0.25 mm and abutting the sintered metal filter 13 on one side thereof, and a supporting member 15 having a thickness of 10 to 100 mm and having a plurality of openings 15d with an aperture ratio of 30 to 60%; and the sintered metal filter 13, wherein the wire netting 14a and the supporting member 15 are disposed in this order from the upstream to the downstream of the flow passage 10b; and the sintered metal filter 13 is fixed to the main body 10a through the seal member 18.
US08221624B2	Floating oil recovery suppressor and viscosity elevator A system for separating liquids of different densities employs a collector shell (17) made up of smooth lines and curvatures. A fairing creates and controls the flow of the liquids (for example water and oil) by gathering, capturing and isolating one liquid beneath the surface of the other liquid (24). The trapped and water pressurized oil is extracted and transferred to a storage container (21). One embodiment, the collector shell (17) is a simple design yet complex in achieving a workable shape that can accomplish all of the above using a small number of moving parts all of which, with the possible exception of the collector shell (17) and the elevator screw (12) are off the shelf items. The collector shell (17) inherently suppresses turbulence. The accumulation of oil captured in the collector bowl (17d) remains in a state of semi-suspension in both rough and normal surface conditions. The only movement of the oil is in a vertical direction when the elevator screw (12) is in motion.
US08221622B2	Polymer composite, water-treatment method using the same and manufacturing method of the same A polymer composite is provided for a water treatment. The polymer composite with excellent workability is capable of adsorbing impurities in water, being rapidly separated from the water using magnetic forces. The polymer composite includes secondary aggregates. The secondary aggregates are formed of clumped particles, the particles being magnetic particles covered with a polymer. The polymer composite has porous structures suitable for adsorbing underwater impurities.
US08221619B2	One piece combination anti-drain back and relief valve A fluid filter and an end cap of the fluid filter are described. The filter may be a spin on oil filter, which includes a combination dual valve element defining an integral anti-drain back valve and an integral relief valve, a retainer assembly for maintaining the combination dual valve element in position in the end cap, relative to the filter. The combination dual valve element includes an ADB sealing lip forming an anti-drain back valve portion, and an RV sealing lip forming a relief valve portion.
US08221615B2	Gasoline sulfur reduction catalyst for fluid catalytic cracking process The invention is a composition that is suitable for reducing sulfur species from products produced by petroleum refining processes, especially gasoline products produced by fluidized catalytic cracking (FCC) processes. The composition comprises zeolite, yttrium, and at least one element selected from the group consisting of zinc, magnesium and manganese, wherein the yttrium and element are present as cations. The yttrium and zinc are preferably present as cations that have been exchanged onto the zeolite. The zeolite is preferably a zeolite Y.
US08221611B2	Device suitable for electrochemically processing an object as well as a method for manufacturing such a device, a method for electrochemically processing an object, using such a device, as well as an object formed by using such a method A device which is suitable for electrochemically processing an object comprises at least an electrolyte-containing chamber, means for supporting the object to be processed in the chamber, a counter electrode disposed in the chamber as well as means for applying an electrical potential difference between the object to be processed and the counter electrode. The device furthermore comprises at least one holder and at least one rod-shaped coelectrode supported by the holder, which rod-shaped coelectrode extends towards the object and which in use has a polarity opposite that of the counter electrode.
US08221609B2	Process for producing rare metal and production system thereof According to one embodiment, a process for producing rare metals includes the steps of: electrolyzing an electrolytic solution to extract a Re oxide at a cathode; recovering the Re oxide, and electrolyzing the Re oxide in a molten salt electrolyte to extract metallic Re; recovering a Nd containing residue solution; treating the Nd containing residue solution to produce Nd oxide; electrolyzing the Nd oxide in a molten salt electrolyte to extract metallic Nd; recovering a Dy containing residue solution; treating the Dy containing residue solution to produce Dy oxide; and electrolyzing the Dy oxide in a molten salt electrolyte to extract metallic Dy.
US08221608B2	Proximity processing using controlled batch volume with an integrated proximity head Methods for plating substrates are herein defined. One method includes providing a plating assembly having a plating source in a plating fluid and a plating facilitator in the plating fluid, and defining a plating meniscus between the plating source and the plating facilitator. The plating meniscus being contained in a path of the plating assembly. The method further includes traversing a substrate through the path of the plating assembly. The substrate being charged so that plating ions are attracted to a surface of the substrate when the plating meniscus is present on the surface of the substrate, wherein the substrate traversing through the path of the plating assembly enables plating across the surface of the substrate. And, inducing a uniform charge in the path where the plating meniscus is formed, such that charge from the plating source is substantially uniformly directed toward the plating facilitator as the substrate that is charged moves through the path of the plating assembly.
US08221601B2	Maintainable substrate carrier for electroplating One embodiment relates to a substrate carrier for use in electroplating a plurality of substrates. The carrier includes a non-conductive carrier body on which the substrates are placed and conductive lines embedded within the carrier body. A plurality of conductive clip attachment parts are attached in a permanent manner to the conductive lines embedded within the carrier body. A plurality of contact clips are attached in a removable manner to the clip attachment parts. The contact clips hold the substrates in place and conductively connecting the substrates with the conductive lines. Other embodiments, aspects and features are also disclosed.
US08221600B2	Sealed substrate carrier for electroplating One embodiment relates to a substrate carrier for use in electroplating a plurality of substrates. The substrate carrier includes a non-conductive carrier body on which the substrates are held, and conductive lines are embedded within the carrier body. A conductive bus bar is embedded into a top side of the carrier body and is conductively coupled to the conductive lines. A thermoplastic overmold covers a portion of the bus bar, and there is a plastic-to-plastic bond between the thermoplastic overmold and the non-conductive carrier body. Other embodiments, aspects and features are also disclosed.
US08221598B2	System for plating A system for plating according to one embodiment includes a plating cell containing plating solution; an anode in contact with the plating solution; a cathode in contact with the plating solution; and a hydrogen electrode in contact with the plating solution.
US08221596B2	High impedance system for generating electric fields Disclosed is a system and method for generating time variant and invariant electric fields (E-fields) for various applications. Generating the E-field utilizes high impedance dielectric materials having a collection of three imperative material properties: high permittivity (∈), high volume resistivity (ρ) and high maximum allowable E-field stress (φ) and physical geometries that take advantage of the manner in which E-fields are divided or distributed in series capacitance networks. The generated E-field can act upon a subject material, including a gas, liquid or solid, wherein the material is stationary or in motion. The method allows an E-field of given intensity to be set up in the subject material with a significantly lower applied voltage Φa, or conversely, a significantly higher E-field intensity with a given applied voltage Φa. The method forestalls electric conduction current through the subject material, thus significantly reducing electric conduction current, energy consumption, ohmic heating, and preempting electrochemical reactions at the electrode/fluid interfaces. Acoustic energy may also be applied.
US08221591B2	Coking drum support system A delayed coking unit with a coking drum having an upper cylindrical portion and a lower frusto-conical portion is supported by means of a support structure surrounding the cone frustum of the lower portion of the drum; the support structure comprises a cone support member having a concave frusto-conical support surface mating with the outer convex cone frustum of the lower portion of the drum so that the drum sits in the cone support element. The support structure further has a weight supporting member or members attached to the cone support member intermediate its upper and lower peripheries which acts or act to transfer the weight of the drum (and contents) downwards to a suitable sub-structure such as a concrete slab. In a preferred embodiment, the drum may also be stayed against lateral forces by means of guide members at the upper portion of the drum.
US08221590B2	Headbox for a machine for producing a fibrous web The invention relates to a headbox for a machine for producing a fibrous web, especially a paper or cardboard web, from at least one fiber suspension, comprising a feed device feeding the at least one fiber suspension, a perforated distribution pipe plate arranged immediately downstream thereof and having a plurality of channels arranged in lines and columns, an intermediate channel arranged downstream thereof, extending over the width of the headbox and having a plurality of means for dosing a fluid in partial fluid streams to the at least one fiber suspension in a preferably adjustable/controlled manner, the means being spaced apart from each other in the width direction of the headbox and the individual means comprising a plurality of dosing channels having respective dosing channel openings on the outlet side and a dosing channel length, arriving at different levels and being connected to a common supply channel. The headbox according to the invention is characterized in that the dosing channel length of the dosing channel is 1.5 times longer than the dosing channel opening of the dosing channel on the outlet side and in that the distance of the dosing channel opening of the dosing channel on the outlet side to the turbulence generator ranges from 0 to 50 mm.
US08221589B2	Method, a blade holder and a doctor apparatus for detaching a web threading tail from a moving surface in a fiber web machine In a method for detaching a web threading tail from a moving surface in a fiber web machine, the web threading tail (12) is detached from a moving surface (23) by means of air that flows from a blow-off blow channel (19) included in a blade holder (14). A trailing blow (26) is directed to the web threading tail (12) using air that flows from a trailing blow channel (17) included in the blade holder (14). The blade holder (14) includes a flow surface (32), and the trailing blow (26) is blown to the same direction with or in a small angle relative to the flow surface (32). The invention also relates to a corresponding blade holder and a doctor apparatus for detaching a web threading tail from a moving surface in a fiber web machine.
US08221584B2	Method and apparatus for removing sheets of fibres from banana plants for the production of paper products A method and apparatus for producing sheets from the pseudostems of banana plants in the family Musaceae, each pseudostem having a longitudinal axis. The method includes the steps of feeding a pseudostem (14) into a workstation, supporting (62, 34) the pseudostem for rotation thereof about its longitudinal axis within the workstation, and contacting the rotating pseudostem along substantially its entire length with a fiber-separating device (38), whereby a continuous sheet of fiber (60) is removed from the pseudostem by the fiber-separating device during rotation. Raw paper may also be made by laminating two or more of these sheets together such that the direction of the generally parallel fibers in at least two adjacent sheets is not aligned and then curing the sheets to form raw paper.
US08221583B2	System for peeling semiconductor chips from tape A semiconductor system for peeling semiconductor chips from tape, comprising: providing an outer housing having an aperture on a top thereof; providing a magnet with a needle base extension; providing needles magnetically held to the magnet; applying a vacuum through the aperture to hold an adhesive material to the outer housing; and extending the needles through the aperture in the outer housing.
US08221582B2	Clamped monolithic showerhead electrode An electrode assembly for a plasma reaction chamber used in semiconductor substrate processing. The assembly includes an upper showerhead electrode which is mechanically attached to a backing plate by a series of spaced apart cam locks. A guard ring surrounds the backing plate and is movable to positions at which openings in the guard ring align with openings in the backing plate so that the cam locks can be rotated with a tool to release locking pins extending from the upper face of the electrode.
US08221578B2	Methods of manufacturing paint roller covers from a tubular fabric sleeve A method of manufacturing paint roller covers is disclosed in which the paint roller covers are manufactured from a seamless, tubular fabric sleeve having a backing made at least in part from a material having a lower melting point than material used for the pile of the seamless, tubular fabric sleeve. The seamless, tubular fabric sleeve is placed onto a cylindrical member, and heat is applied to cause the material having the lower melting point in the backing be activated to cause the backing of the seamless, tubular fabric sleeve to remain in a cylindrical configuration. The activated tubular knitted pile fabric may be finished into paint roller covers by combing and shearing the pile fabric to a desired length, beveling the edges of the paint roller covers, and vacuuming stray fibers from the paint roller covers.
US08221577B2	Fabricating thermoset plates exhibiting uniform thickness A method of manufacturing a flexographic plate having a uniform thickness comprises providing a thermoset layer having at least one uneven side; providing a thermoplastic layer having a first and a second side; attaching the first side of the thermoplastic layer to the uneven side of the thermoset layer thereby forming a flexographic plate; and calendering the flexographic plate via a series of heated pairs of rollers thereby creating a flexographic plate with a uniform thickness.
US08221575B2	Automatic tape laying apparatus and method A method for manufacturing a contoured composite article. A separation distance of dividing elements of a dividing unit configured to divide a tape comprising fiber is adjusted. The tape is fed through the dividing unit to divide the tape into a plurality of inter-connected or separate, substantially longitudinal strips. The tape is laid onto a surface with an automatic tape laying apparatus.
US08221574B2	Top coating for indoor and outdoor temporary removable graphics and system and method for making, applying and removing such graphics A composition for a removable top coating for protecting the exposed face of a temporary removable graphic is provided. A remover for the transferred graphic image is provided that completely dissolves the temporary removable graphic, but does not affect the commonly encountered substrates such as concrete, brick, wooden floors, asphalt surfaces, terrazzo and motor vehicle body surfaces, marine and aeronautical craft surfaces. A method for making, applying and removing the temporary removable graphic is provided.
US08221572B2	Manufacturing method for absorptive article A manufacturing method for an absorptive article according to the present invention includes: placing a continuum of the elastic members 4A and 5A in a desired layout, on at least one surface of a web 7A being transported continuously, while swinging the continuum of the elastic members 4A and 5A in a direction crossing a moving direction of the web 7A; feeding the web 7A on which the continuum of the elastic members 4A and 5A are placed, between a first roll 8, which is rotating in the moving direction, and a second roll 9; and pressing the continuum of the elastic members 4A and 5A, and the web 7A between the first roll 8 and the second roll 9. A recess 20 is formed in a predetermined pattern on at least an outer peripheral surface of the first roll 8, and the continuum of the elastic members 4A and 5A, and the web 7A are pressed between the first roll 8 and the second roll 9 while the continuum of the elastic members 4A and 5A placed in an area 3A corresponding to the crotch portion on one surface of the web 7A faces the recess 20 formed on the outer peripheral surface of the first roll 8.
US08221567B2	Filter media and system and method of manufacturing the same Filter media and a method for manufacturing filter media is disclosed. The filter media includes a corrugated porous filter media layer including a top surface and a bottom surface, wherein the corrugated porous filter media layer includes one or more peaks separated by valleys, a second porous filter media layer including a top surface and a bottom surface, the valleys of the corrugated porous filter media proximate the second porous filter media layer, and an ultrasonically weldable material disposed between one or more of the valleys of the corrugated porous filter media layer and the top surface of the second porous filter media layer.
US08221565B2	Combustion inhibitor coating for gas generants Methods of making and resultant compositions thereof, which include a gas generant having a coating including an inorganic combustion inhibitor. Such coated gas generants are useful in pyrotechnic compositions and ignition materials, and may be employed, for example, in inflatable restraint systems. The ratio of coated and uncoated gas generant bodies within an airbag inflator may be tailored to provide S-curve inflation performance. Spray application of aqueous mixture including the combustion inhibitor onto the gas generant body provides a rapid way to achieve a thin but robust coating.
US08221564B2	Method for manufacturing high strength steel strips with superior formability and excellent coatability A method for manufacturing a steel sheet used for structural members, elements, etc. of automobiles including a front side member, pillar, and the like, and more particularly, a method for manufacturing a steel sheet having a high strength and formability as well as hot-dip galvanizing properties is disclosed. In the method, after an aluminum killed steel slab, which comprises, by weight %: C: 0.05% to 0.25%; Si: 0.1% to 1.5%; S: 0.02% or less; N: 0.01% or less; Al: 0.02% to 2.0%; Mn: 1.0% to 2.5%; P: 0.001% to 0.1%; Sb: 0.005% to 0.10%; the balance of Fe and other unavoidable impurities, is subjected to a homogenization treatment at a temperature range of 1050° C. to 1300° C., the aluminum killed steel slab is subjected to a hot rolling under a finishing hot rolling temperature of 850° C. to 950° C. and a coiling temperature of 400° C. to 700° C., followed by a cold rolling under a cold rolling reduction ration of 30% to 80%, and annealing the cold rolled steel sheet.
US08221563B2	Method of making a diesel-engine crankshaft The invention relates to a method for producing a crankshaft, in special for diesel engines, wherein a crankshaft blank is produced from austempered ductile cast iron, the casting blank is subjected to heat treatment matched to the austempered ductile cast iron whereby the blank acquires high strength and hardness. According to the invention, surfaces which form bearing surfaces for connecting rods and shaft bearings are undersized before the ADI heat treatment. Following the heat treatment a coating is applied to the bearing surfaces, the layer thickness being matched to the undersize and dimensional deviations as a result of the heat treatment. The coated bearing surfaces are finally finish-machined to the finished size without the need of machining the bearing surfaces of the casting blank after the heat treatment.
US08221562B2	Compact strip or thin slab processing of boron/titanium steels A method for casting medium carbon, B/Ti steel product using compact strip processing or thin slab casting. The method can include providing a steel composition including boron and titanium and casting the steel composition into a slab having a thickness between about 25 and 150 mm. The slab can have a cast composition including about 0.23 to 0.30 wt. % carbon, about 0.0010 to 0.0050 wt. % boron, about 0.010 to 0.050 wt. % titanium, about 1.15 to 1.50 wt. % manganese, less than 0.35 wt. % silicon and a Ti/N ratio greater than 2.9. The amount of each element is provided based upon the total weight of the steel composition. The steel slab can be free from cracks and significant defects. Furthermore, the steel slab can be used for electric resistance welded (ERW) products.
US08221561B2	Amorphous alloys having zirconium and methods thereof An amorphous alloy having the general formula of: (ZrxAlyCuzNi1-x-y-z)100-a-bSCaYb, wherein x, y, and z are atomic percents, and a and b are atom molar ratios, in which: about 0.45≦x≦about 0.60; about 0.08≦y≦about 0.12; about 0.25≦z≦about 0.35; 0
US08221560B2	Lead free solder alloy Disclosed herein are a lead-free solder alloy and a manufacturing method thereof. More specifically, disclosed are: a lead-free solder alloy, which comprises 0.8-1.2 wt % silver (Ag), 0.8-1.2 wt % copper (Cu), 0.01-1.0 wt % palladium (Pd), 0.001-0.1 wt % tellurium (Te), and a balance of tin (Sn), and thus has a melting point similar to those of prior lead-free solder alloys, excellent wettability, very low segregation ratio, and excellent weldability with a welding base metal, such that it improves temperature cycle performance and drop impact resistance simultaneously, when it is applied to electronic devices and printed circuit boards; a manufacturing method of the above alloy; and electronic devices and printed circuit boards which include the same.
US08221557B2	Systems and methods for exposing semiconductor workpieces to vapors for through-hole cleaning and/or other processes Systems and methods for exposing semiconductor workpieces to vapors for through-hole cleaning and/or other processes are disclosed. A representative method includes exposing a semiconductor workpiece to a vapor, with the semiconductor workpiece having an opening extending from a first surface of the workpiece through the workpiece to a second surface facing opposite from the first surface. The opening can include a contaminant, and the method can further include drawing the vapor and the contaminant through at least a portion of the opening and away from the second surface of the semiconductor workpiece.
US08221556B2	Copper alloy plumbing hardware, such as valves and tube couplings, and the treatment method for reducing elution of lead This invention relates to a plumbing device made of a copper alloy containing nickel salt, that includes a valve and a tube coupling having at least a liquid-contacting part washed with a cleaning fluid incorporating therein nitric acid and hydrochloric acid as an inhibitor under conditions of a temperature and a duration permitting effective removal of nickel salt, thereby performing nickel salt-removing treatment and causing the hydrochloric acid to form a coating film on the surface of the liquid-contacting part thereby effectively precluding elution of nickel salt from the surface of the liquid-contacting part in the presence of the coating film, wherein the nitric acid has a concentration c in a range of 0.5 wt %
US08221553B2	Method for producing organic light-emitting device A method for producing an organic light-emitting device is provided for an organic light-emitting device having a substrate provided with external connection terminals, organic light-emitting elements provided on the substrate, and a protective film that covers the organic light-emitting elements. The method includes, sequentially, providing a protective film removal layer on the external connection terminals, forming the protective film on the substrate, dividing the substrate on which the protective film has been formed, and cleaning the substrate with water, an aqueous solution, or a solvent. The protective film removal layer and the protective film are removed from the external connection terminals as a result of cleaning the substrate.
US08221552B2	Cleaning of bonded silicon electrodes Methods of cleaning plasma processing chamber components include contacting surfaces of the components with a cleaning solution, while avoiding damage of other surfaces or areas of the components by the cleaning solution. An exemplary plasma processing chamber component to be cleaning is an elastomer bonded electrode assembly having a silicon member with a plasma-exposed silicon surface, a backing member, and an elastomer bonding material between the silicon surface and the backing member.
US08221551B2	Apparatus for producing a reflector Provided is a deposition apparatus that has a metal evaporation source for depositing a reflective layer, a pigment evaporation source for depositing a coloring layer, and a plasma polymerization source (electrode) for depositing a protective layer disposed inside a single vacuum processing room. By carrying out a step of depositing the reflective layer, a step of depositing the coloring layer, and a step of depositing the protective layer in the common vacuum processing room, processes can be simplified and an operation time can be reduced.
US08221547B2	Nitride semiconductor substrate and method for forming the same An initial substrate structure for forming a nitride semiconductor substrate is provided. The initial substrate structure includes a substrate, a patterned epitaxial layer, and a mask layer. The patterned epitaxial layer is located on the substrate and is formed by a plurality of pillars. The mask layer is located over the substrate and covers a part of the patterned epitaxial layer. The mask layer includes a plurality of sticks and there is a space between the sticks. The space exposes a portion of an upper surface of the patterned epitaxial layer.
US08221543B2	Solidification and hardening accelerator for hydraulic binders and process for its preparation The present invention relates to a fluoride-free solidification and hardening accelerator for hydraulic binders, comprising sulfate, aluminum and organic acid, the molar ratio of aluminum to sulfate being less than 0.83.
US08221539B2	Dry pigment preparations comprising anionic additives The invention relates to pigment preparations containing (i) at least one organic and/or inorganic pigment, and (ii) a dispersant of formula (I) or (II), or mixtures of dispersants of formulae (I) and (II), wherein A is C2-C4 alkylene and B is a C2-C4 alkylene different from A, D is propylene, and Q is SO3, CH2—COO, PO3M or QM.
US08221532B2	Nanoporous articles and methods of making same An adsorbent having porosity expanded by contact with a first agent effecting such expansion and a pressurized second agent effecting transport of the first agent into the porosity, wherein the adsorbent subsequent to removal of the first and second agents retains expanded porosity. The adsorbent can be made by an associated method in which materials such as water, ethers, alcohols, organic solvent media, or inorganic solvent media can be utilized as the first agent for swelling of the porosity, and helium, argon, krypton, xenon, neon, or other inert gases can be employed as the pressurized second agent for transport of both agents into the porosity of the adsorbent, subsequent to which the agents can be removed to yield an adsorbent of increased capacity for sorbable fluids, e.g., organometallic compounds, hydrides, halides and acid gases. Also described is a nanoporous carbon composite having porosity that is at least partially filled with material imparting to the composite an enhanced character with respect to characteristics selected from the group consisting of hardness, wear-resistance and toughness, as compared with the nanoporous carbon alone.
US08221528B2	Methods for applying microchannels to separate gases using liquid absorbents, especially ionic liquid (IL) absorbents Methods of using microchannel separation systems including absorbents to improve thermal efficiency and reduce parasitic power loss. Energy is typically added to desorb a solute and then energy or heat is removed to absorb a solute using a working solution. The working solution or absorbent may comprise an ionic liquid, or other fluids that demonstrate a difference in affinity between a solute and other gases in a solution.
US08221525B2	Oxygen enrichment using small-pore silicoaluminophosphate membranes A method of oxygen enrichment in which a gaseous mixture containing O2 molecules and N2 molecules is provided to a feed side of a SAPO molecular sieve, oxygen enrichment membrane having pore sizes suitable for discriminating between O2 molecules and N2 molecules, resulting in selective transport of the O2 molecules through the membrane to a permeate side of the membrane. Also disclosed is a method for producing the membrane.
US08221523B2	Apparatus for the uninterruptible filtering of gas The invention is an apparatus and method for filtering a volume of gas. In one embodiment, the invention is a filtering apparatus having a hollow vessel with inlets and outlets, channels in communication with the inlets and outlets, a form of filter media, and an uninterruptible flow controlling device for regulating the circulation of gas within the apparatus. In another embodiment, the invention is a method incorporating an uninterruptible filtering apparatus to remove evaporated liquid from a volume of gas by passing the gas over a filter media contained within a hollow vessel.
US08221522B2	Filter with memory, communication and pressure sensor The present invention describes a system and method for accurately measuring the pressure within a filter housing. A pressure sensor and a communications device are coupled so as to be able to measure and transmit the pressure within the filter housing while in use. This system can comprise a single component, integrating both the communication device and the pressure sensor. Alternatively, the system can comprise separate sensor and transmitter components, in communication with one another. In yet another embodiment, a storage element can be added to the system, thereby allowing the device to store a set of pressure values. The use of this device is beneficial to many applications. For example, the ability to read pressure values in situ allows integrity tests to be performed without additional equipment. In addition, integrity testing for individual filters within multi-filter configurations is possible.
US08221514B2	Ecologically clean method and apparatus for water harvesting from air The invention provides an ecologically clean method and apparatus for water harvesting from air. The method is based on changing of thermodynamic state properties of air wind getting a rotation and passing through convergent-divergent nozzles. The apparatus is a water condensation engine exposed to humid wind. The constructive solution has no moving solid parts, and the incoming wind is an inherent moving component of the engine. It comprises a cascade of sequentially arranged horn-tubes and a set of stationary wing-like details. Those horn-tubes transform the wind into a fast and cooled out-flowing air flux coming-and-hitting upon the set of wing-like details, where the air portions are accelerated and eddying. The inner static pressure and temperature decrease in the air portions. The decrease in static pressure and temperature triggers off condensation of water-vapors into water-aerosols.
US08221513B2	Low oxygen carrier fluid with heating value for feed to transport gasification Systems and processes for producing synthesis gas. A carbonaceous feedstock can be combined with one or more low-oxygen carrier fluids having a high heating value. The feedstock and carrier fluid, in the presence of one or more oxidants, can be gasified to provide a synthesis gas. In one or more embodiments, at least a portion of the synthesis gas can be recycled for use as the carrier fluid.
US08221512B2	Hydrogen generator and fuel cell system Provided is a hydrogen generator capable of suppressing degradation in capability of a hydrogen generator which is caused by crush of particulate reforming catalyst and of suppressing decrease in reforming efficiency due to decrease in heat transfer efficiency of a catalyzing portion which is caused by the crush of the particulate reforming catalyst. A hydrogen generator comprises a catalyzing portion 50 having particulate reforming catalyst P, and a combusting portion 5 for heating the catalyzing portion 50, the hydrogen generator being configured to generate a reformed gas containing hydrogen while flowing a material gas containing steam in a direction in which the catalyzing portion 50 extends. The catalyzing portion 50 includes a separating member 40. The separating member 40 is disposed on a separating cross-section which is a cross-section of the catalyzing portion 50 in a direction perpendicular to the direction in which the catalyzing portion 50 extends. A plurality of air holes 40D having a shape to inhibit passage of the particulate reforming catalyst P are provided on the separating member 40. An opening having a shape to permit passage of the particulate reforming catalyst P is provided on the separating cross-section.
US08221509B2	Battery and method for producing the same Sheet-shaped mixture layers are placed on both sides of a current collector to form an electrode (positive electrode) with a layered structure. The electrode with a layered structure and a counter electrode (negative electrode) thereof are wound via a separator, while a positional shift in a winding direction is caused between the current collector and the sheet-shaped mixture layers of the electrode with the layered structure, whereby a winding body is formed. The winding body is placed in a battery case (outer can) to constitute a battery. Particularly, in the electrode with a layered structure, by forming the current collector of a plain-woven wire net, a metal foil, expanded metal, a lath, or punching metal, a battery with satisfactory productivity suitable for an intermediate load can be provided at a low cost.
US08221507B2	Removing the silicone coating from coated fabrics and airbags The invention relates to a process for removing silicones present on fibers, yarns or textile sheet materials (substrates) wherein an aqueous preparation is allowed to act on the substrates, and then the thus treated substrates are rinsed to remove the residual silicone, characterized in that said preparation contains from 0.5 to 10% by weight of surface-active quaternary ammonium compounds and from 0.5 to 5% by weight of alkali hydroxide, respectively based on the aqueous preparation. The process is suitable, in particular, for the recovery and recycling of fibrous material and silicones from airbags or coated fabric scraps from the ready-making of airbags.
US08221506B2	Prosthetic walking foot The prosthetic foot (1) consists of three or four laminas, a lower lamina (1a) defining the under-heel and the foot front, a rear lamina (1b) defining the heel and functioning as the Achilles tendon and as the soleus muscle, two upper laminas (1c and 1d) defining the front part of the foot and performing the function of the front tibial muscle, and a connector (2) in proximity to the ankle to serve as a coupling for a tube (3).
US08221504B2	Coating an implant for increased bone in-growth A method of preparing an implant for bone in-growth comprising: providing a metal implant body, the metal implant body having a metal load bearing layer on an outer surface, the metal load bearing layer having a plurality of pores therein, the pores configured to promote bone in-growth into the load bearing layer; providing calcium sulfate hemi-hydrate; providing a diluent; mixing the calcium sulfate hemi-hydrate and the diluent to form a calcium sulfate paste; applying the calcium sulfate paste to the load bearing layer such that the calcium paste substantially impregnates at least a portion of the pores and forms an excess layer of the calcium sulfate paste on an outer surface of the load bearing layer; and wiping the calcium sulfate paste to remove the excess layer and thereby expose the outer surface of the load bearing layer while leaving the calcium sulfate paste impregnated in the pores.
US08221499B2	Infection-blocking dental implant An infection-blocking dental implant in which a threaded portion which contacts bone is roughened except for up to three threads which may be exposed by bone recession after implantation, which have a smooth surface. Preferably, the implant is of titanium or titanium alloy and the threaded portion is roughened by a two-step acid treatment.
US08221492B2	Artificial valve prosthesis with improved flow dynamics An expandable venous valve having a support structure that configured to enlarge the area adjacent to the valve structure such that the flow patterns of retrograde flow are modified in a way that facilitates the flushing of the pockets at the base of the valve area to prevent stagnation of bodily fluid, which in the venous system, can lead to thrombus formation. The enlarged pocket areas can be created by forming an artificial sinus adjacent the valve structure in an unsupported section of vessel wall between two support frame section or the support frame can comprise an expanded-diameter intermediate or proximal section that forms an artificial sinus adjacent the valve structure. In another group of embodiments, the attachment pathway between opposing leaflets and the support frame and/or vessel wall comprises a proximal portion that places the leaflets in extended contact with one another and a distal portion forms a large angle with respect to the adjacent walls such that a large pocket is created at the base of the leaflets. In one embodiment, the attachment pathway extends distally along a pair of substantially parallel longitudinal attachment struts to create an extended leaflet contact area, then angles circumferentially and distally from the former along distal attachment struts to define the bottom edge of the leaflets.
US08221491B1	Tissue supporting devices A new multiple component stent arrangement which allows for initial self-expansion and subsequent deformation to a final enlarged size.
US08221490B2	Helical stent design An expandable tubular reinforcing member used for body lumens such as blood vessels, the reinforcing member being formed of a continuous elongated helical element comprised of spaced undulating portions forming end loop portions and including a plurality of curvilinear connector elements extending between and interconnecting at least some of the adjacent undulating portions of the helical element over its length.
US08221489B2	Device and method for treating a body lumen A device and method for treating a body conduit/lumen having an undesired reduced diameter include delivering an expandable stent in a contracted configuration to a target location. The stent has small cells that form an open tight mesh providing the effective capture of small particles such as thrombi. Preferably, the tight mesh is combined with structure that permits creation of large side openings to accommodate lumen branches.
US08221488B2	Intraluminal stent graft A method of making a tubular intraluminal graft in the form of a tubular diametrically adjustable stent having a tubular covering of porous expanded polytetrafluoroethylene which is less than 0.10 mm thick. The covering may be on the exterior surface of the stent, or on the interior surface of the stent, or both. The covering may be affixed to the stent by an adhesive which is preferably fluorinated ethylene propylene.
US08221484B2	Multi-membrane balloon and method for manufacturing a multi-membrane balloon A multi-membrane balloon (10) for a catheter having an at least double membrane sleeve (20, 40) comprising at least one fillable and emptiable expansion space (46) between a proximal end (12) and a distal end (14), wherein a stiff supporting element (60) surrounds the at least double membrane sleeve (20, 40) and the outer membrane sleeve (20) surrounds one or more inner membrane sleeves (40). The supporting element (60) at least partially takes hold with the outer membrane sleeve (20).
US08221482B2	Flared ostial endoprosthesis and delivery system An intraluminal endoprosthesis having a conically shaped first end and a tubular shaped balloon-expandable stent for a main body is disclosed. The conically shaped first end may form a flare to the main body and is particularly well suited for in ostium use. The first end is preferably self-expanding and the main body is preferably balloon-expandable. Also disclosed is a delivery device for delivering intraluminal ostial endoprosthetic devices, especially those disclosed herein, to a site for deployment. The delivery device may comprise an over-the-wire system or may comprise a rapid-exchange shuttle system. The self-expanding portion of the endoprosthesis is encapsulated in a sheath or other restraining apparatus on the delivery device. The balloon-expandable stent portion of the endoprosthesis is crimped onto a balloon delivery device. The delivery system and endoprosthesis of the present invention allow the endoprosthesis to be partially expanded and relocated if it is determined that it is not located in the proper location. To aid in positioning, the delivery device may comprise marker bands.
US08221479B2	Orthopedic screw insert An insert for receiving a bone screw includes an elongate sleeve having opposed proximal and distal ends and a wall defined by an outer peripheral surface configured for engaging bone and an inner peripheral surface configured for receiving a bone screw extended therethrough. At least one elongate slot is formed in the wall of the sleeve for promoting flexure of the insert. A tool for affixing an orthopedic screw insert within bone tissue includes a socket portion configured and adapted to engage a proximal section of an outer peripheral surface of an orthopedic screw insert. A driver extends distally from the socket portion. The driver is configured and adapted to engage a section of an inner peripheral surface of the orthopedic screw insert distal from the socket portion.
US08221477B2	Implants for creating connections to tissue parts, in particular to skeletal parts, as well as device and method for implantation thereof Implants (7) for forming a positive connection with human or animal parts include a material, such as thermoplastics and thixotropic materials, that can be liquefied by means of mechanical energy. The implants (7) are brought into contact with the tissue part, are subjected to the action of ultrasonic energy while being pressed against the tissue part. The liquefiable material liquefies and is pressed into openings or surface asperities of the tissue part so that, once solidified, the implant is positively joined thereto. The implantation involves the use of an implantation device that includes a generator (2), an oscillating element, and a resonator (6). The generator (2) causes the oscillating element to mechanically oscillate, and the element transmits the oscillations to the resonator (6). The resonator (6) is used to press the implant (7) against the tissue part to transmit oscillations to the implant (7).
US08221474B2	Spinal derotation instruments and methods A method for assembling a system for correcting alignment of a spinal column of a patient is provided. The method includes the steps of engaging first and second implants to a first vertebra; engaging a distal portion of respective first and second implant holders to respective ones of the first and second implants, the first and second implant holders each extending from said distal portion along a longitudinal axis to a proximal end outside the patient; engaging a transverse bridge between and to proximal ends of each of the first and second implant holders; and engaging a derotation handle to the transverse bridge at a location between the first and second implant holders and in a generally parallel orientation to a sagittal plane of the spinal column so that the transverse derotation handle extends transversely to the sagital plane.
US08221471B2	Pedicle screw fixation system A locking mechanism for locking a rod in a screw and rod fixation assembly includes a cap having a sidewall and a locking element extending from at least a portion of the sidewall. Locking mechanism cooperates with a receiver component for a spinal fixation rod to lock the rod in the receiver without requiring application of torque. A method of locking a spinal fixation member in a receiver of a screw fixation assembly includes the steps of placing the spinal fixation member into a channel of a receiver, axially advancing a locking cap into the receiver toward the spinal fixation member without application of any torque, and securing the locking cap in a locked position above the spinal fixation member without application of any torque.
US08221470B2	Spinal fixation system A fastener assembly for a spinal fixation system that is particularly useful in treatment of pediatric and small-statured patients includes a fastener, an attachment member, and a locking member. The fastener has a lower portion for contacting a bone and an upper portion integral with the lower portion. The upper portion has two open channels. Each channel is configured and dimensioned to receive a portion of a longitudinal or connecting member along its circumference. The attachment member is positionable on the fastener and at least partially covers the channel that receives the longitudinal or connecting member. The locking member is operatively associated with the upper portion of the fastener and secures the attachment member and the longitudinal or connecting member to the fastener.
US08221469B2	Pedicle screw with a closure device for securing a rod for stabilization of the vertebral column A pedicle screw with a closure device for securing a rod for stabilization of the vertebral column comprises a screw-in part with a head part, a U-shaped recess in the head part., in which recess the rod is held by the closure device. The closure device comprises a yoke-shaped locking element, which has a collar with a projection on each of the two opposite end regions. One groove is provided on each of the two arms in such a way that the locking element is rotatably placed on the arms. The projections are inserted in the grooves to achieve locking position. A tension screw is screwed into the locking element and rotatably connected to a tension element inserted between the arms, and, in the locked state of the locking element, is able to be tensioned, by means of the tension screw, against the rod inserted in the recess.
US08221467B2	Dynamic spinal stabilization device and systems A dynamic spine stabilization element of a spine stabilization assembly includes first and second spinal rod segments that are coupled to one another via a connector. The connector allows movement of a spinal rod segment with respect to the coupling device and/or with respect to another spinal rod segment. This provides limited angulation (e.g. bending) between spinal rod segments allowing for limited movement of the vertebra connected by the present dynamic stabilization element. The connector may allow pivoting motion of the rod segments relative to the coupling device and relative to the other rod segment such as pivoting motion of one rod segment in a first plane and pivoting motion of the other rod segment in a second plane that is perpendicular to the first plane. The connector may also be bendable or flexible. In this form, the connector allows limited flexing, bending or angulation as between the associated spinal rod segments during use. Moreover, ends of the spinal rod segments may be configured to prevent or limit rotation of the spinal rod segments. The configured ends may cooperate with the coupling device to achieve the limitation on rotational movement.
US08221465B2	Multi-chamber expandable interspinous process spacer An expandable interspinous process spacer is disclosed that includes at least two chambers, one disposed within the other. Each of the at least two chambers can receive an injectable biocompatible material, which advantageously may have different material properties such as hardness. Further, the expandable interspinous process spacer can be changed from a deflated configuration to an inflated configuration. In the inflated configuration, the expandable interspinous process spacer can engage and support a superior spinous process and an inferior spinous process.
US08221459B2	Pedicle screw connector apparatus and method A low-profile rod connector is disclosed that includes two substantially conical surfaces that allows two rods to be secured together. The device is easily manipulated and occupies very little space. The connector allows for the rods to be oriented at a number of different positions prior to securing the rods in a final orientation. Medical implants utilizing the present invention include surgical implants for spine stabilization. One particular application comprises securing the shaft of a pedicle screw to a spinal rod. In such application, since the connector is relatively small, displacement and disruption to nearby tissue is minimized. The connector also has application to external fixation systems which are conducted exterior of the skin surface, as well as other mechanical devices.
US08221457B2	Progressive approach osteosynthesis device and preassembly method The present invention relates to an osteosynthesis device, particularly for spinal support or correction, enabling easier and compact implantation, that can be particularly used in the case of implantation via the anterior approach, and a preassembly method for such a device. Said device comprises implants screwed into two vertebrae and one plate characterized in that the plate is joined to at least one implant by attachment structure able to hold said plate without preventing the implant from rotating on its screwing axis, or without preventing a specified clearance of the plate with respect to the implant. In this way, said attachment structure make it possible to continue screwing the implant, or adjust the position of the plate after the plate has been on the implant.
US08221454B2	Apparatus for performing meniscus repair An apparatus and method of repairing a tear in body tissue includes inserting a needle containing a retaining head from a first insertion position on a first outer surface of the body tissue, through the tear and to a second outer surface of the body tissue. The retaining head is ejected from the insertion needle and grasps the second outer surface in an engaged position. An anchor coupled to the retaining head by a flexible member is advanced from a second insertion position on the first outer surface of the body tissue to a position at least through a portion of the tear. The flexible member extends a distance along the first outer surface of the body tissue from the first insertion position to the second insertion position.
US08221451B2	Inflatable device for enteric fistula treatment Disclosed herein is an implantable fistula closure device. The device may include an expandable longitudinally segmented body including a proximal end and a distal end. The segmented body may further include a plurality of porous bodies and a connecting member operably joining together the plurality of porous bodies. The plurality of porous bodies includes a first porous body with a proximal end and a distal end and a second porous body with a proximal end and a distal end, and the connecting member operably connects the proximal end of the first porous body with the distal end of the second porous body.
US08221449B2	Surgical instrument with removable shaft apparatus and method A surgical instrument includes a shaft having a proximal end and a distal end with an operating device disposed at the distal end. A cable assembly is carried by the shaft and extends proximally to a terminus. A handle assembly coupled to the cable assembly concludes a first handle and a second handle. The first handle includes portions configured to receive the terminus and the proximal end of the shaft while portions of the second handle are configured to receive the terminus of the cable assembly. The proximal end of the shaft and the terminus are simultaneously rotatable to cover the proximal end of the shaft to the portions of the first handle and to couple the terminus to the portions of the second handle. The handle assembly can be made sterilizable with a minimum of non-bearing surfaces, while the shaft assembly can be made disposable and interchangeable with various operating devices. An associated method includes the step of releasably locking the shaft assembly to the handle assembly.
US08221443B2	Submucosal endoscopy with mucosal flap methods and kits Kits and methods for submucosal endoscopic access into body cavities such as the peritoneal cavity and the posterior mediastinum through a submucosal endoscopic procedure in which an opening is formed through the muscularis propria within a bleb. The procedure may result in a mucosal flap formed by separated mucosal tissue within the bleb and the mucosal flap may be advantageously used to assist in closure of the opening.
US08221441B2	Rotary-actuated medical puncturing device The medical puncturing device includes an actuator, a shield, and a skin puncturing assembly. The actuator and shield are movable relative to one another. The skin-puncturing assembly includes a carrier and a skin-puncturing element. A distal end of the skin puncturing element is adapted for puncturing the skin of a patient. The carrier is movable from a retracted position wherein the distal end of the skin-puncturing element is disposed within the shield to a puncturing position wherein the distal end of the skin-puncturing element is exposed to puncture the skin of a patient. The carrier is maintained in the retracted position by interference engagement between the carrier and shield. A drive spring is provided to move the carrier from the retracted to puncturing positions. A retraction spring is provided to return the carrier to a position wherein the shield encompasses the skin puncturing element.
US08221437B2	Device for applying liquid skincare products in combination with vacuum and abrasion A liquid delivery wand includes a centrally located fluid storage chamber. An absorbent pad is located within the working end of the wand for applying the treatment liquid to the skin while a vacuum is applied to the skin through an abrasive coated treatment tip. Coaxial, cylindrical tubes with flow channels between tube surfaces control the flow rate, the pressure drop being established by the close fit and length of adjacent surfaces of the coaxial components. The flow rate of the liquid is adjustable by simply rotating the interfitting components. The chamber that holds the liquid is sealed from the atmosphere at the distal and proximal end. When the wand is connected to vacuum and the distal end contacts the skin, the vacuum applies a negative pressure to the fluids within a fluid chamber. A small portion of liquid is thus transferred to wet the filter pad.
US08221435B2	Device comprising a pin support member and insulation means for fixation to a patients skull during neurological diagnosis, and a method for assembling said device The present invention relates to a device for fixation to a patient during neurological diagnosis, therapy or surgery, in particular during MRI diagnosis. The device comprises at least one fixation pin being made of a non-magnetic, electrically conductive material for fixation to a patient, and at least one pin support member for supporting said fixation pin. An insulation means is arranged so as to restrict the electrical coupling between said pin support member and fixation pin. Said insulation means is sleeve shaped and arranged to at least partly surround said fixation pin. The invention also relates to an insulation means, a pin support member and to a method for assembling a fixation device.
US08221432B2	Method and apparatus for implanting a modular femoral hip An insertion system for implanting a prosthetic component includes a handle, a shaft, and a guide rod. The handle includes an impaction portion. The shaft extends from and is fixed to the handle. The guide rod is removably coupled to the shaft and includes a proximal end adapted to be rotationally fixed within the impaction portion and a distal end adapted to attach to the prosthetic component.
US08221430B2	System and method for manufacturing arthroplasty jigs Disclosed herein is a method of computer generating a three-dimensional surface model of an arthroplasty target region of a bone forming a joint. The method may include: generating two-dimensional images of at least a portion of the bone; generating an open-loop contour line along the arthroplasty target region in at least some of the two-dimensional images; and generating the three-dimensional model of the arthroplasty target region from the open-loop contour lines.
US08221425B2	Percutaneous discectomy and endplate preparation tool Surgical instruments and surgical methods associated therewith are described. The surgical instruments described herein can be used for scraping or for other purposes such as measuring distances between two points in hard to reach locales.
US08221421B2	Sternum fixation device A sternum fixation device for securing parts of a sternum includes first and second removably associated plates. The first plate has an upper surface and a sternum-contacting surface, and at least one hole passing through both of these surfaces for receiving a fastener head. The second plate has at least one attachment member for fixation to the sternum. A release member holds the first and second plates together, and is movably associated with at least one of the first and second plates such that it may be moved to allow separation of the two parts of the sternum.
US08221417B2	Disposable electro-surgical cover elements and electro-surgical instrument Electro-surgical instrument and attachments for converting a mechanical surgical instrument into an electro-surgical instrument are disclosed for applying electrical current to tissue, such as a blood vessel, to seal or cauterize the tissue. A cover element is slidable over a distal end of a component of a mechanical surgical instrument, such as a forceps. Each cover element defines a single pocket or cavity and a single aperture or opening at one end thereof for receiving and surrounding the distal end of the component and an electrically conductive element attached to an outer surface of the cover element. RF energy can be applied to tissue through the electrically conductive elements. After the procedure, the cover elements can be slidably removed from the forceps member and are disposable.
US08221412B2	Medical needles and electrodes with improved bending stiffness A device for penetrating tissue includes an elongated element having a distal end, a proximal end, a body extending between the distal and the proximal ends, and a lumen located within at least a portion of the body, wherein the lumen has a cross-sectional shape that is a polygon. A device for penetrating tissue includes an elongated element having a distal end, a proximal end, and a body extending between the distal and the proximal ends, at least a portion of the body having a cross-sectional profile that is a polygon, wherein the elongated element is a cannula.
US08221405B2	Patent foramen ovale closure device and methods for determining RF dose for patent foramen ovale closure A medical system and device for use in delivering RF energy to a tissue opening and a method for determining an RF dose is disclosed. In one embodiment, the medical device includes an electrode or anchor and one or more devices, such as an impedance electrode, RF electrode and/or thermocouple. The electrode or anchor can be deployed from a delivery shaft inside the left atrium, for example, of a heart and substantially conform to the tissue proximate the tissue opening. Tissue characteristics, such as temperature and/or impedance, can be measured, before, during and after application of RF energy to the tissue, by one or more devices to determine an RF dose. After energy is applied to the tissue between the left and right electrodes, the left electrode can be removed from the left atrium by being received back into the delivery shaft and the delivery shaft thereafter removed from the opening.
US08221404B2	Electrosurgical ablation apparatus and method The present invention relates to the field of electrosurgery, and more particularly to a system that produces a focused plasma for tissue ablation. The system includes a probe and a remote source of a conductive liquid media for providing a flow through the probe that functions as an electrode. A pressurized flow of the liquid media passes through a first larger diameter flow channel in the probe to then increases in velocity as it passes through a smaller diameter flow restriction channel in a working end surface. The flow restriction of the liquid electrode through the flow restriction channel when coupled with high frequency voltage causes instantaneous ignition of a plasma within media flow media within the flow restriction channel. The working end surface thus carries a plasma that when proximate to tissue will cause a controlled, focused ablation.
US08221402B2	Method for guiding a medical device A device and method for ablating tissue is disclosed comprising the steps of acquiring an anatomical image of a patient, correlating the image to the patient, guiding an ablating member within the patient while tracking the position of the ablating member in the patient, positioning the ablating member in a desired position to ablate tissue, emitting ablating energy from the ablating member to form an ablated tissue area and removing the ablating member from the patient.
US08221398B2	Remote-controlled actuator A remote-controlled actuator includes a spindle guide section of an elongated shape, a distal end member fitted to a distal end of the spindle guide section for alteration in attitude and rotatably supporting a tool, and a drive unit housing having a base end of the spindle guide section connected therewith. A rotary shaft for transmitting rotation of a tool rotation drive source within the drive unit housing to the tool and an attitude altering member for altering the attitude of the distal end member by the drive of an attitude altering drive source within the drive unit housing are accommodated within the spindle guide section. A cutting force estimator is provided for estimating the magnitude of at least one component force of a principle force, a radial force and a feed force in a cutting force which the tool applies to a work to be processed.
US08221395B2	Method and apparatus for automatically modifying delivery profile of drug delivery system The present invention relates to an implantable drug delivery device which includes a fluid drug reservoir, a catheter, a controllable fluid transfer device, e.g., a pump or valve, and a drug delivery control means. The control means in accordance with the invention is configured to initially clear a first, or old, drug from the device based on the content of the Current Profile data containing a first, or old, delivery profile. After the old drug is cleared, then the control means automatically modifies the Current Profile data to match a second, or new, delivery profile for controlling delivery of a second, or new, drug.
US08221391B2	Needleless medical connector A valve for selectively permitting a fluid flow between first and second medical implements is disclosed. The valve has a housing with an interface suitable for receiving a connector portion of a first medical device such as a catheter, and a seal made of a flexible material. The seal has a first end in fluid communication with the interface, a second end suitable for receiving the second medical device, and at least one slit in fluid communication with the first end and the second end. The slit defines a restricted fluid flow path and a relatively small interior volume when in an undisturbed state, defines an expanded fluid flow path and a larger interior volume upon the introduction of the second medical instrument into the slit, and retracts to define a restricted flow path and a small interior volume upon the withdrawal of the second medical device from the seal.
US08221389B2	Low profile adaptor for use with a medical catheter An adaptor for use with a medical catheter comprises a housing having a first tubular channel with a first longitudinal axis, a dial having a second tubular channel with a second longitudinal axis, and an adaptor fitting removably connected to the second tubular channel. The dial is rotatable between an open position and a closed position when the adaptor fitting is connected thereto. In the open position the first tubular channel is fluidly connected to the second tubular channel, and in the closed position the first tubular channel is not fluidly connected to the second tubular channel. The dial may be configured such that it is not rotatable between the open position and the closed position when the adaptor fitting is not connected thereto. The housing may comprise an upper housing member, an intermediate housing member, and a lower housing member.
US08221388B2	Biased clamping assemblies A medical clamping assembly includes a housing defining a chamber and a deflecting member operable to slide relative to the housing between a first position and a second position. A conduit is also provided within the housing and is adapted for fluid coupling to a medical device. The medical clamping assembly also includes a biasing element disposed within the housing adjacent to the conduit. The deflecting member is movable relative to the housing between the first position corresponding to an open state of the conduit and the second position corresponding to a closed state of the conduit whereby the biasing element compresses the conduit to substantially close a lumen of the conduit.
US08221380B2	Method for manufacturing a three dimensionally shaped article comprising hip/thigh panels and a hoop from a plus-shaped blank, and such an article The present invention relates to a method for the high production speed manufacturing of articles comprising a closed or hoop structure, such as garments like pants, or absorbent articles like diapers, having a waist- and leg hoops.
US08221373B2	Breast pad and method for producing the same A breast-milk pad can be produced relatively easily, such that it reduces an uncomfortable sensation to the skin surface of a user, and has excellent shape retention properties. A method for producing the breast-milk pad is also disclosed. The breast-milk pad can include a material that is made up by stacking: a back sheet that prevents permeation of liquid; a top sheet that contacts the body; and an absorber that is disposed between the back sheet and the top sheet. The top sheet and the back sheet are bonded to each other in an outer peripheral portion. Cutout portions obtained by cutting the absorber can be formed in positions facing each other at the outer peripheral portion such that cutout width of each of the cutout portions gradually narrows down inwardly. The top sheet and the back sheet can be bonded to each other on the inner side between the cutout portions, and the breast-milk pad can further include bonding portions for bonding inner surfaces of the top sheet together, which are superposed at each of the cutout portions, in a state in which the product is folded up along a folding line connecting the cutout portions facing each other so that the top sheet forms the inner surfaces.
US08221369B2	Fluid voiding apparatus An extra-labia urine voiding apparatus including a container sized and shaped to externally cover a vulval region of a female anatomy. The container has an open side and defines a reservoir that is adapted for receiving urine. The container also includes a surface disposed at a top of the container adapted to face and generally surround a periphery of the vulval region. The voiding apparatus also includes a conduit in fluid communication with the reservoir of the container and adapted for draining urine from the reservoir.
US08221367B2	Disposable urine control device A disposable urine control device for females during urination when in a crouched position. The control device is provided preferably folded flat and preferably packaged in a stack, each including an elongated flexible folded panel formed of disposable material and having side margins preferably narrowing toward a central portion from enlarged end portions thereof. A perimeter sealing bead extends upwardly from, and substantially continuously around the panel perimeter to provide stiffness and sealing against the labia majora of a female to contain urine within the perimeter sealing bead during urination. A flexible elongated conduit is connected at one end thereof in alignment with a urine drainage aperture formed into a central portion of the panel. When the panel and conduit are unfolded for use from a substantially flat folded orientation of the panel and a folded orientation of the conduit, urine is directed through the conduit into a toilet bowl. An inner sealing bead and urine impermeable layers may also be provided.
US08221365B2	Disinfectant delivery system, and method of providing alcohol-free disinfection A disinfectant delivery system and method of providing alcohol-free disinfection to a body to be disinfected, as well as a method of infection reduction by preparation of a patient before an invasive procedure. A blended cloth comprising first fibers and second fibers is provided with the first fibers generally being greater in quantity by weight than the second fibers. A disinfectant solution impregnates the blended cloth, with the disinfectant solution having chlorhexidine gluconate as an active ingredient and having no alcohol. In the method according to the invention, at least one impregnated blended cloth is used to disinfect at least a portion of a body. A plurality of blended cloths can be provided for disinfecting discrete portions of the body. When an invasive procedure is to be performed on a patient, a further method according to the invention of infection reduction comprises using a CHG-impregnated cloth to disinfect at least a portion of the patient at least one day prior to the invasive procedure proximate the location of the invasive procedure.
US08221364B2	Trocar obturator A trocar obturator includes a shaft having a proximal end and a distal end. The shaft also includes an outer surface. A tip member is secured to the distal end of the shaft, the tip member including a first end and a second end, as well as an outer surface. A keyed coupling structure links the tip member to the shaft, wherein the shaft adjacent the tip member tapers to a surface diameter substantially coextensive with the outer surface of the tip member and the tip member adjacent the shaft tapers to a surface diameter substantially coextensive with the outer surface of the shaft.
US08221363B2	Luer activated device with valve element under tension A luer activated device includes an inlet adapted to receive a male luer, an outlet associable with a fluid flow system, and a fluid flow path therebetween. The flow path is defined by an elastomeric flow controller extending between the inlet and outlet and maintained in a tensioned state. When a male luer is inserted into the inlet, some of the tension in the flow controller is relieved, allowing the flow path to deform and change in volume. The flow path is adapted such that the change in volume results in no net fluid displacement or minimal positive fluid displacement when the male luer is inserted into the inlet. Other aspects include tensioned flow controllers having a plurality of sealing layers for the inlet and methods of manufacturing valves having a tensioned fluid flow controller.
US08221359B2	Injection device with cap A drug delivery device capable of working in at least two different modes which includes a dose injection mode and a set-up mode. The drug delivery device automatically changes from the dose injection mode to the set-up mode and vice versa in accordance with the detection of the cover by a cover detection switch. In the dose injection mode doses can be set and injected; in the set-up mode various parameters assisting the use of the drug delivery device can be set. This setting is preferably done by selecting the parameters from a menu, also in this mode historical data stored in the device can be viewed.
US08221358B2	Devices and methods for delivering drug depots to a site beneath the skin Devices and methods are provided for delivering a drug depot at or near the spinal column of a patient. In various embodiments, the drug depot comprises a drug cartridge containing drug pellets for delivery at or near the spinal column of a patient.
US08221354B2	Infusion device with positive pressure elastic bladder reservoir Implantable drug infusion devices, systems and methods for delivering therapeutic substance to a subject that include a bulkhead and an attached reservoir formed by an elastic bladder are disclosed. When filled with therapeutic substance, the elastic bladder is elastically expanded such that the therapeutic substance is held at a pressure above ambient pressure. As the therapeutic substance is removed from the reservoir, the bladder collapses and may conform to the shape of the bulkhead surface over which it is located.
US08221353B2	Intravitreal injection device and system An intravitreal injection system for administering a pharmacological agent formulation to an intravitreal compartment of an eye, comprising (i) an injection member coupled to, or comprising, an internal formulation chamber that is adapted to receive and contain the pharmacological agent formulation therein, (ii) a needle having a first end that is in communication with a formulation chamber and a second injection end, and (iii) a movable platform for positioning the system on the eye, guiding the needle, and limiting the penetration depth of the needle into the eye.
US08221352B2	Disposable safety needle system and safety enclosure means Techniques disclosed herein include a disposable safety needle assembly and safety enclosure for internally shielding a used or contaminated needle. The needle assembly has a needle cannula slidably disposed within a safety enclosure. The safety enclosure includes an internally disposed flexible safety member. The flexible safety member has face portion transversely situated and having a safety feature disposed to the needle and that slides thereon. Retracting the needle within the safety enclosure to a point wherein the sharp tip of the needle is beyond the needle protection section of the flexible member causes the protection section to travel transversely to the direction of motion of the needle. As a result, the safety feature receives the sharp tip of the needle and prevents the needle from exiting the enclosure, thereby maintaining the needle safely after use.
US08221348B2	Embolic protection device and methods of use An evacuation sheath assembly and method of reducing or removing a blockage within a vessel without permitting embolization of particulate matter is provided. The evacuation sheath assembly includes a first elongate tubular member, having proximal and distal ends and a main lumen configured to be placed in fluid communication with a blood vessel. An expandable member is provided on a distal portion of the tubular member and is configured to form a seal with the blood vessel. The evacuation assembly further includes a second elongate tubular member having proximal and distal ends and an inflation lumen configured to be placed in fluid communication with the expandable member and a gas inflator. The gas inflator includes a high pressure gas source and a mechanism for regulating the pressure of the gas delivered by the gas inflator. The gas inflator is configured to be placed in fluid communication with the proximal end of the inflation lumen in order to provide a regulated pressure gas source for inflating the expandable member. A method of treatment of a blood vessel using the evacuation sheath assembly includes advancing the evacuation sheath assembly into the blood vessel through a guide catheter. The expandable member is inflated to provide form a seal between the blood vessel and the guide catheter and a vacuum is applied to the main lumen of the first elongate tubular member to cause retrograde blood flow and carry fluid into the main lumen of the evacuation sheath assembly.
US08221345B2	Insulin pump based expert system An apparatus comprising a pump configured to deliver insulin, an input configured to receive blood glucose data, a user interface, and a controller communicatively coupled to the pump, the input, and the user interface. The controller includes a blood glucose data module to compare the blood glucose data to a target blood glucose level for an insulin pump user. The controller is configured to present a question related to the blood glucose level via the user interface when the blood glucose level is different than the target blood glucose level, receive a response to the question via the user interface, and present a recommended user action based at least in part on the response. Other devices, systems, and methods are disclosed.
US08221343B2	Vibrational catheter devices and methods for making same A vibrational catheter for disrupting obstructions in lumens such as blood vessels includes an elongate flexible catheter body having a proximal end, a distal end and at least one lumen extending longitudinally therethrough, a vibrational transmission member extending longitudinally through the lumen of the catheter body and having a proximal end and a distal end, and a transition connector attached to the proximal end of the vibrational transmission member for coupling the transmission member with a vibrational energy source. The transition connector includes a bore into which the proximal end of the vibrational transmission member extends. The proximal end of the vibrational transmission member is attached within the bore of the transition connector with variable attachment forces such that the transition connector exerts a lowest amount of attachment force on an attached distal-most portion of the vibrational transmission member housed within the bore.
US08221336B2	Blood sensor and blood examining instrument including same A blood sensor comprises a substrate, a spacer attached to the top of the substrate, a cover attached to the top of the spacer. A blood reservoir defined by a substrate hole formed in the substrate. A part of a spacer hole in the spacer and connected to the substrate hole, and a cover hole formed in the cover is connected to the spacer hole. A supply passage is defined by another part of the spacer hole that communicates with the blood reservoir portion, and detection electrodes are formed in the supply passage. The cover projects from the supply passage toward the inside of the blood reservoir portion farther than the substrate and the spacer.
US08221331B2	Apparatus for fetal scalp blood sampling The invention relates to an apparatus for fetal scalp blood sampling, having a shaft, a blade that is mounted removably in the distal end of the shaft and that can be slid by means of a positioning mechanism between a starting position mounted in the shaft and a working position extending beyond the distal end of the shaft, and also having a blood sampling device mounted on the distal end of the shaft. To create an apparatus for fetal scalp blood sampling that is easy to operate and also ensures a high degree of operating safety, it is proposed with the invention that the blade can be fixed by the positioning mechanism in the respective end position.
US08221328B2	Visual indicating device for bad breath The invention provides a breath testing device which includes a visual indicating agent which changes color in the presence of an odor associated with bad breath, such as sulfur and ammonia odors. An example of the visual indicating agent is 4,4′-bis(dimethylamino)-benzhydrol (Michler's hydrol or BDMB) and related dyes having a similar chemical structure. The indicating agent is applied to a substrate which is then inserted into a tube or straw, or which covers one end of a straw. When a user with bad breath blows into the tube or straw, the indicating agent will change color. The breath testing devices provide a quick and affordable means for a user to test their breath, and they may be packaged in discreet, pocket-sized dispensers which can be carried in a pocket or purse.
US08221326B2	Detection of oximetry sensor sites based on waveform characteristics In accordance with an embodiment of the present technique, there is provided methods and systems for detecting the location of a sensor and determining calibration algorithms and/or coefficients for calculation of physiological parameters based on the detected location. An exemplary embodiment includes receiving a signal corresponding to absorption of at least one wavelength of light by a patient's tissue, generating a plethysmographic waveform from the signal, determining an identifying characteristic of the plethysmographic waveform, and determining a location of the sensor based on a comparison of the identifying characteristic with at least one defined criterion.
US08221323B2	Using acoustic energy to compute a lung edema fluid status indication Systems and methods for monitoring lung edema fluid status, such as monitoring the presence or absence of pulmonary edema, in a subject using information about responsive acoustic energy echoes from a lung are described. The system comprises, among other things, an implantable device including an acoustic transducer configured to emit acoustic energy to a lung and to receive one or more responsive acoustic energy echoes from a lung. In an example, the implantable device includes a cardiac function management device having an acoustic window in a body thereof. In another example, the implantable device includes one or more subcutaneous leads. An implantable or external processor circuit is configured to receive information about the acoustic energy echoes to compute and provide a lung edema fluid status indication; such information may include an increased number or special pattern of acoustic energy echoes received or a decreased time between successively received echoes.
US08221322B2	Systems and methods to improve clarity in ultrasound images Systems, methods, and devices for image clarity of ultrasound-based images are described wherein motion sections are compensated with the still sections of the region of interest. Velocity map analysis of regions-of-interest is determined to compensate for instrument motion from motions attributable to structures within the region of interest. Methods include image processing algorithms applied to collected echogenic data sets and the dispensers that use apply air-expunged sonic coupling mediums.
US08221315B2	Cardiac valve procedure methods and devices The present invention discloses devices and methods for performing intravascular procedures with out cardiac bypass. The devices include various embodiments of temporary filter devices, temporary valves, and prosthetic valves.The temporary filter devices have one or more cannulae which provide access for surgical tools for effecting repair of the cardiac valves. A cannula may have filters of various configurations encircling the distal region of the cannula, which prevent embolitic material from entering the coronary arteries and aorta.The temporary valve devices may also have one or more cannulae which guide the insertion of the valve into the aorta. The valve devices expand in the aorta to occupy the entire flow path of the vessel. In one embodiment, the temporary valve is a disc of flexible, porous, material that acts to filter blood passing therethrough. A set of valve leaflets extend peripherally from the disc. These leaflets can alternately collapse to prevent blood flow through the valve and extend to permit flow.The prosthetic valves include valve fixation devices which secure the prosthetic valve to the wall of the vessel. In one embodiment, the prosthetic valves have at least one substantially rigid strut, at least two expandable fixation rings located about the circumference of the base of the apex of the valve, and one or more commissures and leaflets. The prosthetic valves are introduced into the vascular system a compressed state, advanced to the site of implantation, expanded and secured to the vessel wall.
US08221314B2	Capsule type endoscope for sending data in human body communication system A capsule type endoscope which is introduced into a subject to acquire subject internal information and transmits the acquired subject internal information to the outside through the subject has a plurality of electrodes arranged on an outer peripheral surface thereof. An electrode selecting section selects two electrodes with a small transmission power loss from the plurality of electrodes as transmitting electrodes that are utilized to transmit the subject internal information. A transmitting section uses the two transmitting electrodes selected by the electrode selecting section to transmit the subject internal information to the outside of the subject.
US08221312B2	Endoscope An air/water channel is split into smaller-diameter branch channels before the air/water channel enters a bending portion so as to create a space within a joint ring constituting the bending portion. A forceps channel having the largest outer diameter among internal components of the joint rings is disposed at the center of the joint rings. In addition to the branch channels, optical fibers as a light guide, a signal line, and the like are arranged around the forceps channel within the joint rings. By eliminating the created space, a diameter of the joint rings is reduced and thus a diameter of an insertion section is reduced.
US08221311B2	Face tip assembly for an endoscope A face tip assembly for an endoscope for viewing a visually obscured portion of a body cavity and for surgically treating a portion of a body cavity with an operating tool may include at least one operating tool port located in an outer wall surface of the face tip assembly, and the outer wall surface may generally lie in a plane which is disposed at an acute angle with respect to the longitudinal axis of the face tip housing. This outer wall surface may have a generally U-shaped configuration. At least one optical image channel port may be located in another outer wall surface of the face tip housing, and this outer wall surface faces toward the distal end of the face tip housing. The outer wall surface in which the tool port is located extends from the outer wall surface in which the at least one optical image channel port is located, toward the distal end of the face tip housing.
US08221309B2	Endoscope processor An endoscope processor comprising a touch-panel input unit, a mechanical switch unit, and a controller, is provided. The endoscope processor controls an endoscope system. The touch-panel input unit comprises a touch-panel monitor. A command to carry out a function of the endoscope system is input via a command-input display displayed on the touch-panel monitor. The mechanical switch unit is manipulated to carry out at least one function among a light-switching function, a pump-switching function, and a white-balance-start switching function. The controller carries out a function corresponding to the command input via the touch-panel input unit or the mechanical switch unit.
US08221308B2	Endoscope apparatus with advancement/retreat detection means A direction of movement, an insertion amount and an insertion force amount at a time when an insertion section of an endoscope is inserted in a large intestine, which is an object of an inspection, are detected by detection unit. The direction of movement, the insertion amount and the insertion force amount of the insertion section are displayed on a display device which is separably disposed. Thereby, a high-precision insertion operation can simply and easily be realized, and a handling operability is improved.
US08221307B2	Electronic endoscope An electronic endoscope (2) of the type including: a distal end (14) including an illumination element and an electronic image acquisition member; a probe (12), one of the ends of which is connected to the distal end; and control elements (10) connected to the other end of the probe, characterized in that the probe includes a plastically malleable portion (20) suitable for preserving, under the effect of its own weight when the endoscope is in use, the shape which has been conferred on it by an operator, the malleable portion carrying the distal end of the endoscope.
US08221304B2	Operation microscope There is disclosed an operation microscope in which an observing and displaying system of an operating instrument are selected, and an endoscope image for observing a dead angle of the microscope and a navigation image are selectively displayed in a microscope observation field, so that a tomographic image, three-dimensionally constructed image, and the like can be selectively displayed in a display screen in accordance with a treatment position displayed in a monitor or an observation position of the operation microscope.
US08221303B2	Intra-ventricular cardiac assist device and related method of use A system and method for cardiac assist of a heart. The system comprises a catheter on which is mounted an inflatable balloon configured for inflation inside a ventricle. The system preferably includes a fluid pump and a processor configured to activate the pump to inflate the intra-ventricular balloon in the ventricle during a predetermined first phase of the cardiac cycle and to deflate the balloon during a predetermined second phase of the cardiac cycle. The predetermined first phase may be the end of the slow ejection phase corresponding to the ascending part of the T wave, and the predetermined second phase may begin at the peak of systolic augmentation resulting from inflation of the balloon which corresponds to the descending part of the T-wave. The method of the invention includes delivering the balloon to a ventricle of the heart and transiently inflating the balloon to achieve a predetermined intra-ventricular systolic pressure.
US08221301B2	Centrifuge having an angle adjuster and centrifuging method Provided are a centrifuge that rotates about a rotation axis to separate a material and a method of centrifugal separation. The container is coupled to the centrifuge to freely pivot upward and downward on a pivoting axis vertical to a rotation plane. The container has an opening at an upper end thereof and holds a material inside. An angle adjuster raises the central axis of the container beyond a perpendicular angle with the rotation axis while the centrifuge is rotating in order to arrange the opening of the container downward with respect to the rotation plane and point an end of the container opposite to the opening of the container upward with respect to the rotation plane, and allow a portion of layers formed during centrifugal separating to flow down through the opening.
US08221298B2	Apparatus and method for folding film edges Pre-stretched films may be used to increase the rate at which loads can be wrapped and to minimize the exertion required when using traditional handheld film. However, the edges of pre-stretched films are easily damaged, which may result in tearing or failure of the film during use. The present disclosure describes devices, systems, and methods for folding the edges of the film, resulting in a film that is less susceptible to damage and easier to use.
US08221297B2	Storage system for tool holders A tool storage system stores tool holders for use in machine tools. The tool holders hold tools such as milling cutters, taps, drills, reamers, chamfering or deburring tools or the like. The tool holders may have standard taper-shanks. A receptacle is provided for each tool holder. The receptacles are arranged on a generally vertical array and hold the tool holders generally horizontally. The tool holders may be retained by engagement of a pull stud in the receptacle. The generally vertical array arrangement permits storing a large number of tools in a small footprint. In embodiments, a computer system provides functions for managing the tools and/or jobs in which the tools are used.
US08221294B2	Trampoline system A fence surrounds a trampoline and extends above the rebounding surface, reducing the risk of injury. Shock absorption is aided by a support system of independent poles. Variable placement net fasteners also are detailed.
US08221291B1	Athletic equipment including a health and/or impact sensor Athletic equipment is provided including sensors to monitor the effectiveness and health of the athlete. Contact sensors identify stresses or impacts in real time, and interactively, during the training or competition. Concurrently, a health sensor, obtaining and transmitting indicia corresponding to the physical condition of the athlete (such as heart rate, blood pressure, etc.) can be communicated simultaneously and synchronously with the monitored stress or impact date for use in optimizing athlete performance or monitoring athlete physiology. Such data can be transmitted to a remote location as well. In either case, such information can provide a system for optimizing athlete performance, rather merely tracking historical information. Real time analysis and physiological-performance correlations can be achieved, thereby minimizing the need, or extend of an iterative training regime.
US08221289B2	Engagement/disengagement of transmission with auxiliary gearbox Embodiments which selectively engage a motor with auxiliary equipment and a final drive assembly of the motor vehicle are disclosed. A transmission of such a motor vehicle may include a transmission input shaft to receive power from the motor, a transmission output shaft, and clutches and associated gears that define power delivered by the transmission output shaft based upon power received by the transmission input shaft. An auxiliary gearbox may include a transmission input gear associated with the transmission output shaft, an equipment output gear to power the auxiliary equipment, and a drive output gear to power the final drive assembly. The motor vehicle may further include a transmission control module to engage the transmission input gear with the equipment output gear by transitioning among locking the transmission output shaft, disengaging the clutches to reduce torque on the transmission output shaft, and placing the transmission in an unlocked neutral state.
US08221288B2	Electro-hydraulic control system diagnostics Various embodiments of methods, apparatus and systems that diagnose and/or detect faults of an electro-hydraulic control system for a transmission are presented. Some embodiments, adjust a main line pressure of the electro-hydraulic control system and detect faults based upon changes in a pressure switch resulting from such adjustments of the main line pressure. The pressure switch may be incorporated into a control main valve or a clutch trim valve of the electro-hydraulic control system.
US08221287B2	Vehicle and controller thereof A vehicle comprises a driving state detecting device configured to detect a driving state, a command signal output device configured to output a detected command signal indicating an engine driving power change command, an opening degree signal output device configured to output a detected opening degree signal, a valve drive device configured to drive a throttle valve; and a controller which is configured to set a target opening degree of the throttle valve based on the detected command signal and to control the valve drive device to cause an opening degree to match the target opening degree. The controller is configured to set, according to the driving state, the target opening degree to a smaller value than when the command signal and the opening degree signal are normal, when at least one of the command signal and the opening degree signal is abnormal.
US08221286B2	Method for controlling a friction-type continuously variable transmission and a transmission equipped with means for carrying out the method A method for controlling a normal force exerted in a frictional contact of a friction type continuously variable transmission with a rotatable input shaft and a rotatable output shaft, includes the steps of: generating a first parameter signal that is representative of changes in one of, or a ratio or difference between both of, a rotational speed of the input shaft and a rotational speed of the output shaft, generating a second parameter signal that is representative of changes in the normal force in the frictional contact of the transmission, generating a third parameter signal that is representative of and is preferably proportional to the multiplication of the first and second parameter signals, and: controlling the normal force in the frictional contact in dependence on a characteristic of the third parameter signal.
US08221284B2	Automotive drive apparatus An engine, an electric motor-generator, an oil pump, an air conditioner, and a first power transmitting means that performs power transmission among a crank shaft of the engine, a rotating shaft of the electric motor-generator, and rotating shafts of the oil pump and the air conditioner are included. The first power transmitting means has: a crank pulley; a first electric motor-generator pulley; an oil pump pulley; an air conditioner pulley; a first belt that is wound around these pulleys; and a first one-way clutch that is interposed between the rotating shaft and the first electric motor-generator pulley so as to transmit a rotational driving force from the crank shaft to the rotating shaft without transmitting a rotational driving force from the rotating shaft to the crank shaft, and the electric motor-generator is motor driven while the engine is being driven.
US08221276B1	Hydraulic motor apparatus A hydraulic motor assembly having a motor, gear reduction set and axle disposed in a housing is disclosed. A brake assembly may be mounted externally to the axle housing portion of the assembly to provide braking for the output axle. The housing may be formed of separate components, including the axle housing portion, an external surface of a ring gear and a hydraulic motor port block.
US08221273B2	Apparatus, system and method for archery equipment An apparatus is configured for inclusion in an arrow, where the apparatus includes a device configured to provide feedback to a user concerning the arrow shot from a bow, and a processor coupled to the device, the processor configured to control an operation of the device at least during a flight of the arrow.
US08221272B2	Method and apparatus for a golf mat A golf mat is disclosed comprising a body portion or ground sheet; and a means for holding the body portion in a position which is elevated a first distance above a ground surface. The means for holding the body portion may be connected to the body portion substantially perpendicular to the body portion. The body portion and the means for holding the body portion may be configured so that when the body portion is placed so that it is substantially parallel to the ground surface and elevated above the ground surface, and the means for holding the body portion is in contact with the ground surface, the majority of the body portion is not in contact with the ground surface so that there is a cavity beneath the body portion in which natural grass from the ground surface can grow without being restrained at least to a height of the first distance. The body portion of the golf mat may include a plurality of openings, wherein natural grass from the ground surface can grow through the plurality of openings of the body portion.
US08221271B1	Stance and rotational swing trainer A stance and rotational swing training device is provided. The device comprises a base with a front foot stop adjustably attached to a top surface of the base for receiving a user's front foot. The user's back foot is received by a rotatable foot pedal rotatably attached to the top surface of the base. The rotatable foot pedal comprises a circular base with a peripheral toe stop that prevents the user's toes from sliding off the foot pedal. An angled riser is rigidly affixed to the top surface of the base adjacent to the foot pedal. The riser guides the heel end of the user's back foot and forces the heel to rise as the user swings a sporting implement, such as a baseball bat or golf club.
US08221270B1	Combination sporting practice assemblies A combination sporting practice assembly includes a stem, a first structure, a second structure, and a basketball hoop. The stem extends between first and second ends. The first and second structures are releasably engaged with the first and second ends of the stem, respectively. The basketball hoop is releasably engaged with at least one of the stem, the first structure, and the second structure. The combination sporting practice assembly is selectively reconfigurable between different configurations.
US08221269B2	Personal golfing assistant and method and system for graphically displaying golf related information and for collection, processing and distribution of golf related data A personal golfing assistant system is comprised of software running on a PDA attached directly or remotely to a GPS receiver that enables the user to survey and/or electronically capture geophysical golf data. A handheld device connected to or integrated with a GPS receiver can instead be used. Software allows a golfer to use a handheld PDA/GPS unit during the course of play to mark a ball location automatically and/or determine the distance to golf course targets and/or objects, and to analyze golf related data and generate statistics. The system can send a set of parameters tailored for a specific course to a real time tunable GPS to adjust for optimal performance and can adjust measurements to compensate for environmental condition changes. The system provides an improved graphical method for measuring and displaying distances between a golfer and a golf course object, for displaying multiple measured distances along a line of sight between a golfer and a golf object or target, and for orienting a target or object on a display to coincide with a user's line of sight. There is also provided a method for collecting and uploading golf course geographic information services (GIS) data to an internet accessible server, processing the uploaded data, distributing data upon an authorized user request, and downloading the requested data to an electronic device.
US08221263B2	Golf clubs and golf club heads having fluid-filled bladders and/or interior chambers Golf club heads include: (a) a club head body having a ball striking face and defining a rear cavity; (b) a fluid-filled bladder in the cavity; and (c) a retaining member holding the fluid-filled bladder in the cavity. Other club heads include: (a) a club head body having a ball striking face and defining a rear cavity; and (b) an insert member in the rear cavity, wherein the insert member interior includes one or more chambers facing the rear surface of the ball striking face. The chamber(s) may cover at least 30% of a total surface area of the interior surface of the insert member and/or at least 30% of a total interior major surface area of the rear cavity. Golf clubs including these club heads and methods of making such golf clubs and golf club heads also are described.
US08221261B2	Golf club head having a multi-material face A golf club with a multi-material face is disclosed herein. More specifically, the golf club head in accordance with the present invention has a striking face that forms a pocket, wherein the pocket is filled with a secondary material having a lower density to improve the performance of the golf club head. The multi-material face disclosed in accordance with the present invention may generally have a characteristic time slope of greater than about 5 and less than about 50, wherein the characteristic time slope is determined based on the various data points collected according to the United States Golf Association's (USGA's) Characteristic Time (CT) test.
US08221258B2	Wood-type golf club head with adjustable sole contour A wood-type golf club head with an adjustable keel zone member is disclosed herein. The golf club head includes a body and an adjustable keel zone member. The body has a front portion, a crown portion and a sole portion. The body also having a heel end, a toe end and an aft end. The sole portion has only a single keel point. The adjustable keel zone member is disposed within a keel zone of the sole and located preferentially with respect to the center of gravity. The keel zone member is capable of adjusting the face angle of the wood-type golf club head.
US08221257B2	Golf free swing measurement and analysis system The presented invention relates to a method for determining the effectiveness of a golfer's swing without the requirement of the club head making contact with a golf ball. More specifically, the present invention relates to a measurement and analysis system comprising a first module that attaches to the club head and captures measurement data and relative position data during the entire swing, further first module wirelessly communicates bi-directionally with a second module that is further connected to a user interface device and computational engine where feedback results are calculated and conveyed to the golfer. The system provides comprehensive feedback for swing characterization including detailed swing timing metrics, dynamic club head orientation and motion metrics and dynamics shaft action metrics all referenced to the spatial domain.
US08221252B2	Bowling ball with indicia and method therefor A bowling ball with an indicia is provided. A method for manufacturing such a bowling ball is also provided. The indicia may be preformed and attached to the core of the bowling ball before the outer layer of the bowling ball is created.
US08221247B2	Transmission device having overload protection subassembly A transmission device includes a first transmission mechanism comprising a first rotatable member and a first transmission member fixed to the first rotatable member for rotating together with the first rotatable member; and a second transmission mechanism comprising a second rotatable member and a second transmission member fixed to the second rotatable member for rotating together with the second rotatable member. The second transmission member received in the first transmission member, and the second transmission member being magnetically connected with the first transmission member. When a load applied to the first transmission mechanism is less than a predetermined value of the first transmission mechanism, the first transmission member rotates together with the second transmission member by a magnetic force generated therebetween, which in turn makes the first transmission mechanism rotates with the second transmission mechanism together.
US08221246B2	Entertainment chair An entertainment chair includes a base, a bottom surface positioned on a lower portion of the base and a seating surface positioned opposite the bottom surface. The entertainment chair further includes a support surface formed or removeably attachable with respect to the bottom surface and permitting 360 degrees of rotation of the base relative to a floor surface. The entertainment chair further includes an internal control for translating movement of a user to an entertainment system and may further include a means for operably connecting the entertainment chair to an entertainment medium for receiving a signal produced by the entertainment medium.
US08221245B2	Method and apparatus for planning and customizing a gaming experience The invention includes a system and method for planning and customizing a gaming vacation. Initially, a central controller receives preference and configuration data from a user at a user terminal. A preparation code is then determined and associated with the configuration data. The configuration data and the associated preparation code are transmitted from the central controller to a casino server. The central controller provides feedback regarding the user's requests. The feedback may include, for example, marketing offers for the user and/or configuring a gaming device according to the configuration data associated with a preparation code received from a user at the gaming device.
US08221244B2	Table with sensors and smart card holder for automated gaming system and gaming cards Methods and systems are disclosed for intelligent tracking and/or play and/or management of card gaming use an intelligent card distribution or holding device with detectors for determining the value and unique identity of individual cards and for recording card play. Playing cards are equipped with a read/write data storage connected to a transponder and/or incorporated into electromagnetic writable particles or smart particles (smart dust). A system of the invention records various game play events on the playing cards themselves during game play and optionally also in a database on the system. In specific embodiments, the principal scanning and writing elements and electronic and optical interfaces are embodied into a hand-held card holder (HHCH). The system can scan playing cards, scan gaming chips, indicate a player's win/loss/draw, increase or decrease player betting positions, and compute awards to players based on their playing activity.
US08221242B2	Products and processes for providing a video game incorporating venture capital funding In an embodiment, products and processes permit a player to obtain funding for developing game environments. Funding sources include taxes, fees, licenses, bond issuance, loans, investors, commercial paper, convertible debt, bills, notes, debt issuance, promissory notes, venture capital, the issuance of private shares, transforming the game environment into a public company through an initial public offering, or through a follow on offering such as the issuance of common stock, preferred stock, and treasury stock.
US08221236B2	Game process control method, information storage medium, and game device Each note is detected from input sound in units of detection time at specific time intervals. Whether or not the player's input sound coincides with a reference melody set for an egg OB selected for causing a character to be created is determined based on the detected notes, and the character set for the egg OB is created when the input sound has been determined to coincide with the reference melody. Whether or not the input sound coincides with the reference melody is determined based on (1) the distribution of the notes included in the input sound with respect to the passage of time, or (2) the total count of each note included in the input sound.
US08221233B2	Computer program product An object of the present invention is to propose image processing technology whereby even a player with a low skill level can enjoy a shooting game with more, excitement. To achieve this object. according to the present invention; if a player outputs a slow regeneration request signal when processing transits to the status where an enemy-character is about to fire a bullet, the enemy-character and the bullet fired by the enemy-character are regenerated slowly. By this, the player can aim at the bullet with extra time.
US08221231B2	Server based meter model softcount and audit processing for gaming machines Systems and methods for metering accounting activities on gaming machines are disclosed. Remote metering can be had for a gaming machine having a master gaming controller, an external cabinet housing a display device and one or more acceptors, dedicated meters, and communication paths between the master gaming controller and display device, and between meters and acceptors. Dedicated meters are located outside and remote from the external cabinet, and are adapted to track continuously at least one item of accounting information associated with the gaming machine. Such meters can be recognized by a gaming regulator as the official meters for the gaming machine, and can be located at a central location in close proximity to other dedicated meters associated with other gaming machines. Such meters can be individual discrete physical devices secured along dedicated communication lines, or can be electronic meters residing on a single server.
US08221230B2	Video gaming device and method of wagering on a virtual football game This invention is a computerized football game comprising steps to establishing and displaying a game clock, receiving the player's selection information representing a kickoff reception request, calculating a current field position according to the set of kickoff return results, (a) receiving the player's selection information representing an offensive play request from the set of predefined plays, (b) updating the current field position according to the deep zone set of play advancement information if the current position is in the deep zone or according to the mid zone set of play advancement information if the current position is in the mid zone or according to the near zone set of play advancement information is the current position is in the near zone and the goal line has not been reached or until a touchdown is achieved or the game clock expires or a first down is not achieved after four tries.
US08221219B1	Gaming machine displaying one wagered-on game symbol and method of play A wagering base game controlled by a processor in a gaming machine playing only one game symbol for game play in a display in response to a wager. The processor transforms the wagered-on only one game symbol to reveal only one random game result in the display. The revealed game result corresponds to a random one of a number of different game results for the wagered-on only one game symbol. The processor provides a credit in the wagering game when the revealed game result for the wagered-on only one game symbol provides an award other than a null award.
US08221216B2	Method of gaming, a gaming system, and a game controller A method of gaming including: selecting in each game round a plurality of symbols for display to a player in a set of display positions arranged in a plurality of rows and columns, subsets of the display positions corresponding to respective ones of a plurality of reels, each reel comprising a plurality symbols; controlling the correspondence of display positions to reels so that at least one game round is a diagonal spin game round in which at least one of the reels is arranged to spin diagonally such that it corresponds to display positions in a plurality of neighboring columns; determining an outcome for each game round based on the selected symbols.
US08221211B2	Gaming machine and method A gaming machine of the present invention has: a roulette unit 3 for executing a roulette game; an image display device 10 for executing a slot game in parallel with the roulette game; an operating section displayed on the image display device 10, the operating section being capable of making BET operation while predicting a result of a game executed at least one of the roulette unit and the image display device; and a controller for controlling gaming operations in the roulette game and the slot game and controlling payout processing of a gaming value responsive to a payment. This controller performs control so that a result of the slot game is established by applying the result of the roulette game to the slot game.
US08221207B2	Gaming machine with selection state repetition between stages A gaming environment, in which a payout corresponding to a selection item selected by a player is provided, is described. Especially a gaming environment, in which in the second stage screen, when a symbol of “STRAWBERRY” is displayed on the position of the treasure boxes 101 which is in an open state, the game is proceeded to the final stage form the second stage based on that the player touches the next stage button 103B though the touch panel 11, the open and close states of each treasure box 101 on the final stage screen becomes the same as those on the second stage screen, is described.
US08221203B1	Knives for rotary chopper assembly of a combine harvester A rotor chopper assembly including a chopper rotor having a mounting lug. A knife blade includes a body having an opening arrangement configured to receive a retention device securing the body to a member that is rotatably connected to the mounting lug of the chopper rotor. During unobstructed operation of the rotor chopper assembly, the body is centrifugally urged radially outward from the mounting lug. In response to the body striking an obstruction during operation of the rotor chopper assembly, the body is urged into rotational movement until the retention device abuts a stop formed in the mounting lug. An angle subtended between axes defining unobstructed operation and stop abutment is different for at least two openings of the arrangement of openings formed in the body.
US08221201B2	Window with a ventilation device A ventilation device for ventilation of a building having a double-window construction with an air space. The device communicates with the open air space and has four throttles. The first and the second throttles can selectively cut off the passage of air from the air space into a first and a second chamber, respectively, of the device. The third throttle can selectively cut off the passage of air from the first chamber and into the building. The fourth throttle can selectively cut off the passage of air between the open air space and the first and the second chamber. Temperature-sensitive actuators can activate the throttles, selectively adjusting air flow.
US08221192B2	Magnetic-recording-disk test-head and method of manufacturing a magnetic-recording disk using the magnetic-recording-disk test-head A magnetic-recording-disk test-head. The magnetic-recording-disk test-head includes a slider, a test pad and a slider-surface-shape control mechanism. The slider includes a leading edge and a trailing edge. The test pad is disposed at a trailing-edge side of the slider and is configured to remove and to detect asperities on a magnetic-recording disk. The slider-surface-shape control mechanism is configured to change a shape of an air-bearing surface of the slider and is disposed at a leading-edge side of the slider.
US08221191B2	CMP apparatus and method of polishing wafer using CMP A CMP apparatus is provided with a polishing pad, a film thickness sensor for measuring a thickness of a film being polished on a wafer via the polishing pad, a polishing pad thickness measuring unit for measuring the thickness of the polishing pad, a dresser for dressing the polishing pad, and a polishing control unit for switching polishing conditions in response to a fact that an output value from the film thickness sensor has exceeded a threshold value. The polishing control unit has a memory unit for storing a threshold value corresponding to the thickness of the polishing pad after dressing when the polishing pad is dressed.
US08221187B2	Molded non-woven fabrics and methods of molding Methods of molding a non-woven fabric are provided. The methods include selecting a non-woven fabric having a web of fibers having a uniform fiber orientation in all directions, compressing the non-woven fabric between a top mold and a bottom mold, and maintaining the non-woven fabric between the top and bottom molds for a predetermined dwell time to define a molded depth and a molded diameter in the non-woven fabric.
US08221186B2	Garment Certain embodiments of the disclosure relate to a garment comprising: a brassiere comprising a right portion comprising a right support cup and at least one right portion fastener, and a left portion adjacent the right portion and comprising a left support cup and at least one left portion fastener, the left and right support cups being securable to the body of a wearer; and a camisole panel, the camisole panel sized to extend at least between the right support cup and the left support cup and comprising at least one right panel fastener and at least one left panel fastener, the at least one right panel fastener releasably fastenable to the at least one right portion fastener, and the at least one left panel fastener releasably fastenable to the at least one left portion fastener to releasably fasten the camisole panel to the brassiere.
US08221183B2	Universal disc-shaped connectors The present invention provides a versatile construction kit that can be used to easily form models of virtually any conceivable person, place or thing including a variety of vehicles, buildings, people, animals, weapons, machinery, caricatures, objects and the like. The construction kit comprises plural disc-shaped connectors that are connectable by way of a tongue-and-recessed retainer mechanism and optionally also by way of interconnectable notches by which they can be perpendicularly and detachably interconnected and/or optionally by way of a tongue-in-slot mechanism. The universal connectors are so versatile they can form virtually any geometric, regular, irregular, asymmetric, or symmetric configuration.
US08221181B2	Electron multipliers and microchannel plates An electron multiplier can be fabricated by depositing an electron emissive material on a reticulated substrate, and forming the reticulated substrate into the electron multiplier.
US08221177B2	Organic EL panel including an element substrate dehydrated in a shorter time and method for manufacturing the same An organic EL panel is produced with high productivity by a method in which a first protective film (planarizing layer) can be dehydrated in a shorter time without increasing the number of steps up to the step of forming a second protective film (separation film). The second protective film has regions at which the first protective film is exposed between first electrodes.
US08221174B2	Amphibious vehicle An amphibious vehicle achieves a stable ride, maneuverability, and high speed. The vehicle includes a hull having a “V” center portion with outboard sponsons. The sponsons reside between the front wheel wells and the rear wheels wells for improving lift and transition to planing. Shallow tunnels begin in rear portions of the front wheel wells and taper into the sponsons to release water trapped in the wheel wells. Inward facing turning edges also reside between the front and rear wheel wells and improve in-water handling. Wheels are retractable by pneumatic cylinders in parallel with air shock absorbers and suspension cutout in the hull allow the suspension to lower through the hull. Flaps reside under suspension members and rise to cover the suspension cutouts when the wheels are retractable when the wheels are raised to reduce drag. A Morse cable couple a rack and pinion unit to a jet drive.
US08221173B2	Water jet propulsion watercraft A water jet propulsion watercraft includes an engine, an exhaust channel, and an engine control unit. The engine includes a combustion chamber arranged to combust fuel therein, an exhaust port arranged to discharge exhaust gas after the combustion of the fuel in the combustion chamber, an exhaust valve arranged to open and close the exhaust port, an intake port arranged to pass air and the fuel into the combustion chamber, and an intake valve arranged to open and close the intake port. The exhaust channel is connected to the exhaust port of the engine and provides a channel through which the exhaust gas, discharged from the exhaust port, flows. The engine control unit is arranged to control the engine such that at least one location in a path leading from the exhaust channel to the intake port is blocked when the engine is stopped.
US08221169B2	Fanning module, fanning strip, and cable management panel A cable management fanning module includes an elongated base extending in a linear direction defining a longitudinal axis, and having a first end and an opposite second end. A plurality of cable retainers extend from the base, wherein each cable retainer includes a finger extending from the base to a distal end. The first and second ends of the base define an interlocking arrangement having reciprocal shapes, wherein the fanning module is mateable with additional fanning modules on one or both of the first and second ends having a reciprocal shape so as to form a fanning strip.
US08221168B2	Plug connector for a star quad cable A plug connector for a cable having at least two signal conductors, in particular a star quad cable, having a signal conductor part and an insulating part which holds the signal conductor part. The signal conductor part has a spring lug, electrically and mechanically connected to a signal conductor, wherein the insulating part has an axial hole and a spring lug passes through each of said axial holes, wherein the holes are arranged to hold the spring lugs at a physical distance from one another. The spring lugs project beyond the insulating part at the plugging-side end and are bent over in such a way that the respective bent-over portions of the spring lugs run from the plugging-side end in the direction of the cable-side end on an outer face of the insulating part and can be resiliently elastically deformed in the radial direction.
US08221166B2	Phantom power saver power tap An apparatus, system and method are disclosed for eliminating phantom power wastage utilizing a power tap. An insulation casing creates a receiving space for a printed circuit board which mounts male blades, female receptacles, phantom power indication and a mechanical electrical switching capability is disclosed. The conductive male blades and female receptacles create a cross pattern for a two pronged power tap that allows miniaturization of the power tap so as to allow full access to adjacent electrical outlets. Switching states include normally open which permits zero power flow and normally closed which permits power indication and allows power to flow from conductive male blades to conductive female receiving receptacles.
US08221165B2	Connector assembly with an integrated fuse A connector assembly includes a housing, an input conductor, and an output conductor. The housing is configured to mate with a mating connector. The input conductor is held in the housing and extends between a receiving end and a coupling end. The receiving end is configured to receive electric current from a power source. The coupling end is configured to join with a fuse inside the housing. The output conductor is held in the housing and extends between a transmission end and a joining end. The joining end is configured to couple with the fuse inside the housing. The transmission end is configured to convey the electric current to a first electric load. The input conductor and the output conductor are electrically coupled with one another via the fuse to provide a fused conductive pathway within the connector assembly over which the electric current passes from the power source to the first electric load.
US08221164B1	Modular cable clamp with high impedance surface A cable terminating and grounding apparatus and method may comprise a backshell including a cable terminating and grounding adapter shield which may comprise a cable receiving and positioning portion comprising a plurality of individual cable passages around the outer rim of the receiving and positioning portion; and, a gathering portion adjacent the receiving and positioning portion comprising a plurality of individual cable receiving slots around an outer periphery of the gathering portion, each slot having a side wall receiving a cable shield enclosing one or more wires comprising the cable. A gathering mechanism may engage each of the cable shields oppositely from the respective slot side wall and force the respective shield into engagement with the respective slot side wall. There may be a cable passage in a center portion of the receiving and positioning portion and the gathering portion. A locking portion of the adapter shield may engage a connector.
US08221157B2	Connector assemblies with integrated wiring diagrams and methods of using the same Disclosed are connector assemblies having an integrated wiring diagram or being in conjunction with a tool having an integrated wiring diagram, and methods of using such connector assemblies or tools. The connector assemblies include wire entry ports for insertion of respective wires depicted on the wiring diagram. The connector assemblies have at least one housing having a wiring diagram on the at least one housing, on a receptacle that holds the at least one housing or on a tool that temporarily holds the at least one housing.
US08221156B2	RJ-45 connector A connector includes a main body, a cable extending from a rear end of the main body, and a light guide post assembly with two spaced light guide posts formed on a top and fixed to the cable adjacent to the main body. A resilient latch is formed on a top of the main body. A back-end of each light guide post extends upward to form a protrusion capable of transmitting light to a top of the light guide post.
US08221155B2	Splice restraint and mating indicator The present invention relates to a splice restraint for use with sleeves that attach to joints. The splice restraint includes a first securing member constructed and arranged to be received in a groove of a first sleeve that is installable on a first leg of a joint, a second securing member constructed and arranged to be received in a groove of a second sleeve that is installable on a second leg of the joint, and a strap connecting the first securing member to the second securing member. The strap having a length determined by the distance between the groove on the first sleeve and the groove on the second sleeve when the first and second sleeves are properly installed on the joint. The splice restraint provides a visual indication that the sleeves are properly installed on the joint, as well ensures that sleeves will not be displaced after the lineman leaves the site.
US08221147B2	Electrical connector An electrical connector including a housing provided thereon with an opening through which a flexible printed circuit board (an FPC) is inserted into the housing, a plurality of conductive contacts arranged on the housing, a conductive shell mounted on the housing for covering partially the same and provided with a holding member, and a movable lever, wherein the holding member comprises an arm portion extending from the conductive shell to the inside thereof, an engaging projection provided at an end of the arm portion for engaging with an engaging edged portion provided on the FPC inserted in the housing so as to hold the FPC, a pressure receiving portion extending from the engaging projection for receiving pressure from the movable lever and an indicating portion extending from the pressure receiving portion to take up selectively first and second positions for indicating a state of the holding member, and the indication portion taking up at least one of the first and second positions is able to be visually checked from the outside of the conductive shell.
US08221137B2	Mini display port structure A mini display port structure is provided for receiving a connector insert. The mini display port structure includes a circuit board unit and a receptacle unit. The circuit board unit has a base board, wherein an opening is formed on one side of the base board. A portion of the receptacle unit is accommodated in the opening of the circuit board unit and is connected to the base board. Accordingly, the circuit board unit is elevated at a certain position within the height of receptacle unit, and thus the height of the receptacle unit can include the height of the circuit board unit at the same time, thereby shrinking the height of the mini display port structure after the circuit board unit is assembled for making a compact mini display port.
US08221136B2	Electrical connector with two connector bodies mounted on opposite surfaces of a PCB An electrical connector assembly includes a PCB and a first and a second connector body. The first connector body includes a first housing defining a first coupled face and a mounting face perpendicular to the first coupled face, and first contacts including first contacting portions exposing to the first coupled face and soldering portions exposing to the mounting face and fitly connect on a first surface of the PCB. The second connector body is assembled to the first connector body and includes a second housing including a mating portion with a lengthwise mating slot and a second coupled face confronting with the first coupled face and second contacts including mating portions extending in the lengthwise mating slot and second contacting portions exposing to the second coupled surface and pressing against the first contacting portions. The second housing defines mounting portions seating on a second surface of the PCB.
US08221135B2	Socket connector having resilient positioning member securing IC package therein A socket connector includes a socket body and a plurality of contact terminals received in the socket body. The socket body includes an upper surface, a plurality of sidewalls extending upwardly from the upper surface. The upper surface and the sidewalls jointly define a cavity for receiving an IC package therein. At least one of the sidewalls is provided with a resilient arm having two ends connected to the sidewall and a close-loop slot behind the resilient arm. The resilient arm is provided with a positioning member extending toward the cavity.
US08221134B2	Solderless connector assembly A connector assembly is provided for communicating electrical signals between a pin connector having a plurality of connector pins and a remote location. The assembly comprises a connector defining a connector top surface and a plurality of pins extending therethrough, the pins each defining a pin contact surface extending above the connector top surface less than 0.1 inches. A collar is engaged about the connector body, the collar having an upper surface substantially coplanar with the connector top surface. A flexible cable has a plurality of electrical connectors extending therethrough, the cable defining a plurality of cable contact pads being in electrical communication with the flexible cable conductors. A retaining member is engageable to the collar for urging the flexible cable contact pads into electrical communication with the pin contact surfaces.
US08221131B1	Sequentially connectable electrical outlet system having male and female electrical outlets rotatably connected A sequentially connectable electrical outlet system, having a unisex plug assembly having first male and female swivel assemblies, and first male and female lock assemblies. A male outlet assembly has a second male swivel assembly and a second male lock assembly. The unisex plug assembly and the male outlet assembly are rotatably connected. A female outlet assembly has a second female swivel assembly and a second female lock assembly. The unisex plug assembly and the female outlet assembly are rotatably connected. At least two unisex outlet assemblies each comprise third male and female swivel assemblies, and third male and female lock assemblies. The at least two unisex outlet assemblies rotatably connected to the unisex plug assembly. A reel assembly defines a cavity to receive the unisex plug assembly, the male and female outlet assemblies, and the at least two unisex outlet assemblies.
US08221129B2	Wearable wound simulant A wearable wound simulant including a skin replica having the appearance of a particular region of the human body, examples including but not limited to a leg, arm, torso, or stomach, and a wound disposed along the skin replica is described. The skin replica includes a plurality of bendable layers arranged to replicate the visual and tactile properties of human tissues and at least one tear resistant layer comprised of a fabric material disposed between two bendable layers. The tear resistant layers are less stretchable than the bendable layers so as to prevent the bendable layers from stretching beyond their failure threshold. Design elements of the present invention facilitate the visual, tactile, and functional aspects of a battlefield wound so as to allow for the diagnosis of injuries associated therewith. Furthermore, the present invention allows for the insertion of a needle or the like, the probing and/or packing of wounds, the compression of vascular simulants to stop or limit blood loss, and the replacement of dislodged organs.
US08221127B1	Subliminal or near-subliminal conditioning using diffuse visual stimuli A method comprises: repeatedly presenting to a subject a training stimulus; presenting to the subject a diffuse, non-imaged visual stimulus along with the training stimulus; and presenting the diffuse, non-imaged visual stimulus to the subject without the training stimulus. The training stimulus elicits from the subject a selected physiological, psychological, emotional, or mechanical response. The diffuse, non-imaged visual stimulus is presented without the training stimulus so as to elicit the selected response. The diffuse, non-imaged visual stimulus is presented via a visual display and comprises a selected spatial pattern or arrangement of deviation of a selected parameter of the visual display from a reference level of that parameter. The diffuse, non-imaged visual stimulus is arranged so as to be perceived by the subject only at a subliminal or near-subliminal level. A video display and electronic processor can be arranged to present the training stimulus and the diffuse, non-imaged visual stimulus.
US08221125B2	Electronic presentation of world time zones An electronically generated simultaneous display of the local time within multiple time zones in the world is adjusted to accommodate local time arising from Daylight Saving Time. A preferred modified south polar projection of the Earth which schematically depicts the Northern Hemisphere is divided into geographical time zones. Each geographic time zone is associated with a time marker that points to an adjacent time scale. Either the geographical time zones or the time markers are adjusted in order to correctly display the ongoing time changes resulting from the continuous observation of Daylight Saving Time in time zones of the world. As further features, a user may adjust the display to present a hypothetical time and the corresponding times experienced in different time zones around the world. A user may have a specific time zone highlighted by invoking data, such as a city name, a telephone area code or an address book contact reference, which is associated with specific time zone. Conversely, highlighting a time zone may invoke a list of data associated with that time zone, e.g. city names, countries.
US08221122B2	System and method for aircraft mission modeling An expert system and method for aircraft mission modeling using a matrix application, a preferred embodiment of which is incorporated into Mission Modeler software used in conjunction with Satellite Toolkit (STK) software. More generally, the invention is an expert system that draws on an extensive set of basic building blocks that represent standard aircraft maneuvers and concepts, and assembles those building blocks into complex and realistic sequences that represent aircraft motion with very high fidelity. One benefit of this invention is that it provides a simple system and method for users with no piloting experience to generate highly realistic flight paths.
US08221115B2	Fuel combustion A system includes a first source containing a liquid fuel, a second source containing a gaseous fuel, and a combustion burner connected to the first and second sources and selectively in fluid communication with the liquid fuel and the gaseous fuel to receive the fuels. The burner is capable of switching between combustion of the liquid fuel and combustion of the gaseous fuel without modification to the burner or the system.
US08221114B2	Mold for fabricating an optical fiber connector A mold for fabricating an optical fiber connector is provided. The mold includes a mold body, a core pin and a positioning block. The mold body defines a molding chamber, and the molding chamber has a lens forming portion for forming a lens. The core pin is configured for insertion into the molding chamber and forming an optical fiber insertion hole. The core pin includes a first portion and a second portion thinner than the first portion. The positioning block is configured for being arranged in the molding chamber. The positioning block includes an engaging hole for engagingly receiving the second portion.
US08221112B2	Method for retaining a vascular stent on a catheter A method of securely mounting a stent on a balloon of a catheter. The method generally includes crimping a stent on a balloon of a catheter at least one time, and positioning the balloon with the stent thereon within a polished bore of a mold formed at least in part of a metallic material. The balloon is pressurized and heated within the mold, or within a sheath, in two stages as the stent is restrained from radially expanding. The method may include crimping the stent onto the balloon one or two times during processing. The method increases retention of the stent on the balloon catheter following sterilization.
US08221111B2	Mold, method of forming the same, and method of producing polycrystalline silicon substrate using the mold Disclosed is a mold wherein one bottom surface member (2) and four lateral surface members (3) are assembled. The sides of each lateral surface member (3) are respectively provided with a projection (5) and a recess (6) for combining the lateral surface members together, and the projection (5) of one lateral surface member (3) is engaged with the recess (6) of the adjacent lateral surface member (3). By using the one bottom surface member (2) and four lateral surface members (3), a mold can be assembled or disassembled without using screw or bolts. Consequently, the assembly or disassembly work of the mold is dramatically simplified, thereby improving work efficiency significantly.
US08221110B2	Device for expanding a tubular elastic body A device for expanding a tubular elastic body, the device comprises a rigid tube to be introduced into at least a part of the elastic body and keep the elastic body in an expanded state, and an expansion means adapted to expand the elastic body and arranged to be introduced into a first end of the rigid tube. The expansion means is adapted to be movable inside the rigid tube and when the expansion means is fully introduced in the rigid tube, the expansion means protrudes at a second end of the rigid tube and thereby forms a transition between the rigid tube and the expansion element. One end of the expansion means is provided with a radially resilient expansion element with a width decreasing in the introduction direction of the expansion means into the first end of the rigid tube.
US08221108B2	Punch A punch (10, 110) for forming a tablet is described. The punch includes a cam surface (24, 124) which in use contacts a compression surface (62). The cam surface includes a substantially planar flat portion (14, 114), the flat portion having a non-circular shape when viewed along a direction (20) normal to the plane of the flat portion.
US08221107B2	Electrically driven mold clamping unit on an injection molding machine The invention relates to a mold clamping unit on a plastic injection molding machine, the unit having a clamping mechanism for opening and closing an injection mold, the mechanism having a servo motor as the drive motor (21). The drive motor drives at least one spindle drive (10) which has a spindle nut (12) and spindle which work together on a bearing position (14). A cooling system with cooling channels (25) is provided for removing heat from the clamping mechanism. A more efficient cooling of the spindle drive is achieved in that the cooling channels (25) penetrate the bearing position (14) of the spindle drive (10) and/or one of the cooling plates (23) assigned to the bearing position.
US08221104B2	Screw compressor having a slide valve with hot gas bypass port A compressor includes a slide valve (24) having a passage that can be in fluid communication with a discharge plenum (22) and a suction plenum (20). The slide valve (24) position may be axially adjusted to control an amount of refrigerant that is compressed between a male rotor (14) and a female rotor (12) in the compressor based upon a system control scheme that determines capacity demand. The passage (28) is in fluid communication with the discharge plenum (22) and the suction plenum (20) when the slide valve is in a fully unloaded position or a partially unloaded position. A compressor housing blocks an opening to the passage when the slide valve (24) is in a fully loaded position. The location of the opening (36) in the slide valve determines what point in axial travel of the slide valve that fluid bypass begins.
US08221099B2	Windshield washer pump with breather hole cover A fluid pump assembly is disclosed for performing in a damp environment. A pump member is provided that drives a quantity of fluid. A pump housing encloses the pump member and includes a breather hole for circulating cooling air around the pump member during operation. A cover is provided that substantially covers the breather hole and defines a tortuous path that enables air to circulate through the breather hole while preventing entry of water thereto.
US08221097B2	Actuator with grooved piston for a fluid infusion device An apparatus for delivering a fluid includes a housing, an inlet in the housing for receiving the fluid, and an outlet in the housing for discharging the fluid. A piston channel is provided within the housing through which the fluid flows from the inlet to the outlet. An actuator is positioned within the housing and is moveable between a retracted position and a forward position, the actuator defining a piston chamber for storing fluid received through the inlet when the actuator is in the retracted position and for driving the fluid stored in the piston chamber toward the outlet when the actuator transitions from the retracted position to the forward position. The actuator includes an armature and a piston coupled to the armature and moveable within the piston channel. The piston is provided with a groove in an outer surface for conducting fluid from the inlet to the outlet.
US08221096B2	Compressor arrangement with stator welded to a housing A compressor has stator of a motor is installed in a closed container, on two planes normal to the center axis 1a of the container. On each of the planes, the stator is welded to the container at three welding points. This mounting arrangement on two planes with three welding points on each plane minimizes the amount of movement of the stator in the direction of the center axis.
US08221095B2	Method and apparatus for protection of compressor modules against influx of contaminated gas A method for protection of compressor modules against undesirable influx of contaminated gas, comprising a pressure housing (3) which by means of one of more sealing elements (4) is generally divided into a first compartment (8) equipped with a compressor (2) and a second compartment (7) equipped with a gas-filled motor (1), the compressor and the motor being drivably connected to each other by at least one shaft (9), is distinguished by protecting the second compartment (7) with motor (1) against direct influx of contaminated gas from the first compartment (8) with compressor (2) by means of compressed gas that is supplied from a withdrawal point (13) at the first or intermediate stage of the compressor, or from the compressor outlet (16), and by introducing the compressed gas directly into the seal (4) or in between two or more seals so as to flow through the at least one seal (4) back to the first compartment (8). The invention also relates to an apparatus for use in connection with the method.
US08221082B2	Reinforced impeller and method An impeller is provided having a first plate, a second plate, a plurality of blades being positioned between and connected to the first and second plates, and at least one brace member having first and second planes positioned between and connected to two blades such that the brace extends generally perpendicular from the first blade and extends from the second blade at an angle.
US08221081B2	Turbomachine having an unducted fan provided with air guide means A turbomachine having two unducted external fans mounted to contrarotate about a common axis, the fans constituting respectively an upstream fan and a downstream fan, is disclosed. At least some of the blades of the upstream fan carry an air guide device on their radially outer end portions, the air guide device being outwardly oriented on going from upstream to downstream and serving to deflect the vortices that are formed in the vicinity of the blade tips of the upstream fan radially to outside the blades of the downstream fan.
US08221080B2	Method for improving the flow conditions on the propeller or fan of an aircraft engine and accordingly designed hub cone At a propeller (1) or a fan (2) of an aircraft engine, part of the inflowing air—at the air stagnation point forming at the tip (8a) of the hub cone (8)—is conducted into an interior of a hub cone via air inlet openings (9) and, via air outlet openings (10) in an area with minimum static pressure at the downstream end of the hub cone, on a circumference of the latter and at a velocity essentially corresponding to the velocity of the air inflow, is injected into a thick boundary layer on the hub cone, essentially in the direction of flow, thereby accelerating the boundary layer to the velocity of the air inflow. This enables the inflow of air also to the root areas (4a, 6a) of the fan blades/propeller blades (4, 6), to be effected at an aerodynamically favorable, less steep inflow angle.
US08221078B2	Methods and system for providing power and signals in a turbine Power and signals may be transmitted from a root portion of an extendable rotor blade to a moving tip portion using a slide block and a slide channel. The slide block is configured to fit within the slide channel and includes a conductive element that comes into contact with a conductive element of the slide channel. The tip portion may be attached to the slide block such that as the slide block moves along the slide channel, the tip portion is extended or retracted accordingly. The conductive elements may be fixed within each of the slide block and slide channel so that when the tip portion is retracted or extended, the conductive elements do not move.
US08221076B2	Method of controlling the pitch velocity of a wind turbine blade and control system therefore A method of controlling at least one wind turbine blade during the stopping process of the rotor in a wind turbine system is disclosed. The method optimizes the control velocity of the process in response to one or more feedback values of the system and/or one or more feedback values from the surroundings of the system by altering the angular pitch velocity from 10°/sec during the initial stage of the stopping process to 5°/sec at the final stage of the stopping process. A control system and a wind turbine as well as use hereof are also disclosed.
US08221074B2	Fan ring shroud assembly A shroud assembly for an engine cooling fan positioned between an engine and a radiator includes a ring shroud, a radiator shroud, and a flexible boot. The ring shroud is mounted adjacent to the fan and includes a locking feature. The radiator shroud, which is mounted to the rear of the radiator, has a first end with a first aperture for receiving air flowing rearwardly through the radiator, and a second end with a second aperture for discharging air received by the first aperture. A first end of the flexible boot engages the locking feature of the ring shroud to secure the flexible boot to the ring shroud. A second end of the flexible boot contacts the radiator shroud so that the boot provides fluid communication between the ring shroud and the radiator shroud.
US08221070B2	Centrifugal impeller with controlled force balance An impeller for a centrifugal pump that includes a disk-shaped shroud having a central axis, a front surface, a rear surface, and a circular perimeter, and a hub at the center of the shroud, the hub having an axial bore. The impeller further includes a first set of vanes on the front surface of the shroud, the first set of vanes extending radially inward from the perimeter towards the hub, a second set of vanes on the rear surface of the shroud, the second set of vanes extending radially inward from the perimeter towards the hub, a balancing area on the rear surface of the shroud, the balancing area extending radially outward from the hub, and a number of openings in the shroud, the number of openings configured to allow a fluid to pass from one side of the shroud to the other.
US08221068B2	Hydraulic machine member with an abrasion-resistant reinforced edge and a hydraulic machine using this member This hydraulic machine member has at least one flow of water passing through it, and comprises at least one wetted surface extending between two edges of the member, at least one of the edges of the member and part of the adjacent wetted surface being reinforced and formed by at least one removable solid element made from material having a high resistance to abrasion.
US08221067B2	Compact multiphase pump Rotodynamic machine for compressing a multiphase fluid comprising at least one gas phase and one liquid phase.The machine comprises at least one mobile wheel 6 rotating around an axis A-A′, mounted in a housing 1, and at least one fixed wheel 7 secured to housing 1. Mobile wheel 6 comprises a hub fitted with at least two blades 20 so as to form at least two channels delimited by hub 8, housing 1 and two of said blades 20. The channels have a centrifugal part.The length of one of the channels defined as the ratio of the volume of a channel to the maximum orthoradial area of said channel, measured in a plane perpendicular to the axis of rotation, ranges between 10 cm and 20 cm, and the ratio of the area of the largest orthoradial channel cross-section to the area of the smallest orthoradial channel cross-section is less than or equal to 3.

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