Document Document Title
US08067879B2 Piezoelectric device
A piezoelectric device includes a piezoelectric substrate, a conductive pattern which is provided on one main surface of the piezoelectric substrate and which includes an IDT electrode, a supporting layer which is arranged on the one main surface of the piezoelectric substrate so as to surround the periphery of an IDT-forming region in which the IDT electrode is provided and which has a thickness greater than that of the IDT electrode, and a cover layer which is arranged on the supporting layer and which covers the IDT-forming region. The supporting layer includes removed sections provided at a plurality of positions at least in a region close to the IDT-forming region, the removed sections being obtained by partially removing a portion of the supporting layer to be bonded to the one main surface of the piezoelectric substrate.
US08067877B2 Anti-EMI ultrasonic transducer
An anti-EMI ultrasonic transducer has a conductive casing, a piezoelectric ceramic board having an opening, a conductive shelter, a first and second wires and an encapsulation. A first electrode face of the piezoelectric ceramic board faces to the opening and a second electrode face is mounted inside the conductive casing. The conductive shelter is mounted inside the conductive casing or covered to the opening, so the piezoelectric ceramic board is encapsulated in the conductive shelter and the conductive casing. Since the second signal wire is connected to the conductive shelter mounted inside the conductive casing, the conductive shelter and the conductive casing and the second electrode face of the piezoelectric ceramic board are commonly electronically connected to a voltage signal transmitted by the second signal wire. Therefore, the conductive shelter and the conductive casing are constituted to an EMI shelter for the piezoelectric ceramic board to resist external EMI signal.
US08067874B2 Motor apparatus including Lundell motor having Lundell-type rotor
A Lundell motor apparatus controls a field current passed to a rotor field coil and an armature stator coil current to generate a required torque. When the field current is If, the armature current is Ia, a d-axis inductance is Ld, a q-axis inductance is Lq, a q-axis current as a q-axis component of the armature current is Iq, a d-axis current as a d-axis component of the armature current is Id, a field torque is Tf, a field flux is φf, a reluctance torque is Tr, and a combined torque of the field torque and the reluctance torque is ΣT, the d-axis current Id is passed to the stator coil within a phase angle range where the combined torque ΣT becomes larger than the field torque Tf to generate reluctance torque Tr which is equal to (Ld−Lq)Id·Iq in addition to the field torque Tf.
US08067871B2 Permanent magnet rotating electric machine and electric car using the same
A permanent magnet rotating electric machine comprises a stator having stator windings wound round a stator iron core and a permanent magnet rotor having a plurality of inserted permanent magnets in which the polarity is alternately arranged in the peripheral direction in the rotor iron core. The rotor iron core of the permanent magnets is composed of magnetic pole pieces, auxiliary magnetic poles, and a stator yoke, and furthermore has concavities formed on the air gap face of the magnetic pole pieces of the rotor iron core of the permanent magnets, gently tilting from the central part of the magnetic poles to the end thereof. In a permanent magnet rotating electric machine, effects of iron loss are reduced, and an electric car using highly efficient permanent magnet rotating electric machine are realized.
US08067869B2 Hollow actuator
A hollow actuator includes a motor section, a reduction gear section, a brake section, a rotation position detecting section, and a shaft having a hollow shape and transmitting rotation, wherein the motor section and the brake section are disposed in a same chamber.
US08067868B2 Stator structure of outer rotor multipolar generator
In a stator structure 1 of an outer rotor generator, a pressing portion 33 provided on a first portion 31 of a connecting terminal 30 is configured to protrude inward in the radial direction of an annular coupler 20 when the connecting terminal 30 is attached to the coupler 20. The coupler 20 is formed with a circular cylindrical guide protrusion 23, and an outlet of a stator winding 5 having wound on a salient pole 10b is configured to be guided by the guide protrusion 23, bent inward in the radial direction and reach the pressing portion 33. After fusing processing, the first portion 31 on which the pressing portion 33 is provided is bent at a right angle toward a side opposed to a side with which the stator winding 5 is connected, and then a distal end thereof is locked at a lock portion 26.
US08067867B2 Motor with neutral bus ring connecting multiple motor coils
A stator includes multiple motor coils. The motor coils include multiple U-phase coils, multiple V-phase coils and multiple W-phase coils which are arranged in a circumferential direction of a motor. A neutral bus ring connects the motor coils together. The neutral bus ring is divided into multiple bus ring members. Each bus ring member connects together any one of the U-phase coils, any one of the V-phase coils and any one of the W-phase coils.
US08067866B2 Central electricity distribution member for rotary electric machine
A central electricity distribution member for a rotary electric machine, comprising connecting bus bars of respective phases for connecting, among coils of respective phases wound around a stator of the rotary electric machine, the coils of the same phases; a connecting bus bar for a neutral point for connecting the coils of the same phases wound around the stator of the rotary electric machine; a circular holding groove capable of receiving the respective connecting bus bars as the respective connection bus bars are insulated from one another; a bus bar insulating portion formed using insulating material; a bus bar-side positioning portion provided on each of the connecting bus bars; and an insulation-side positioning portion provided on the bus bar insulating portion, for performing positioning between the respective connecting bus bars and the bus bar insulating portion in cooperation with the bus bar-side positioning portion.
US08067854B2 Output circuit
A buffer driving capability control device is provided which can suppress occurrence of radiated noise due to a load driven by large driving power in the case where loads differing in driving power are connected to one terminal. The device includes an output buffer which can switch between the driving capability for driving a load requiring large driving power and the driving capability for driving a load requiring small driving power, and also includes a control period for driving the load requiring the large driving power and a control period for driving the load requiring the small driving power, and during the respective control periods, switches the driving capability of the output buffer to the ones suitable for the corresponding loads.
US08067853B2 Power supply system
The power supply system includes a generator, a transformer circuit, and a battery. The generator generates electric power of a first voltage. The transformer circuit boosts the electric power of the first voltage to a second voltage. The battery is connected, via the transformer circuit, to the generator and stores electric power of the second voltage obtained by the boosting by the transformer circuit. At least one of actuators is connected on the generator side of the transformer circuit, so as to be supplied with the electric power of the first voltage.
US08067852B2 Fluid driven electric power generation system
A tubular housing includes at least one fixed helical vane formed onto the inner surfaces of the tubular housing in a spiral and adapted to direct fluid into a spiraled flow and focus fluid onto a fan blade assembly associated with an alternator system and located within the tubular housing before a system exhaust. A generator cone can be mounted near the center and front of the fan blade assembly facing fluid passing through the tubular housing. As fluid passes over the generator cone it experiences compression between the generator cone and housing resulting in increased pressure and velocity of the fluid, thereby increasing rotational speed of the generator blades and generator as the compressed, spiraled fluid passes through the blades and exits the tubular housing. The system can be used for fixed or mobile applications in water, wind and manually induced air flow.
US08067851B2 Differential pressure generator
An electrical generator (10) powered by fluid pressure in a flow line includes a turbine housing (23) and control valve (11). The turbine housing houses a rotor (29) and a plurality of turbine blades (33) which are rotated by fluid passing from the flow line through the turbine housing. A bearing (22) within the turbine housing guides rotation of the rotor, and supports a plurality of magnets (28). Cap member (23) is sealed to the turbine housing, and a stator (40) external of the cap member generates electricity in response to a plurality of rotating magnets.
US08067845B2 Method for the operation of a wind energy plant at sudden voltage changes in the grid
A method for the operation of a wind energy plant with a rotor, which transfers a driving moment to a generator via a drive train, wherein the generator provides a pre-settable generator moment acting opposite to the driving moment and is connectable to a grid, characterised in that after a sudden voltage change in the grid, the generator moment is controlled depending from the phase position of a torsional vibration of the drive train.
US08067841B2 Semiconductor devices having a resin with warpage compensated surfaces
A semiconductor device including: a die pad, a die on the die pad, and resin encapsulating the die and forming an isolation thickness over the die pad, the resin including a mounting aperture and a major surface configured for mounting to an external device, the major surface having a non warpage compensation portion adjacent the die and a warpage compensation portion in a relatively thermally inactive zone with an approximate discontinuity and/or abrupt change in gradient between the non warpage compensation portion and the warpage compensation portion.
US08067830B2 Dual or multiple row package
A dual or multiple row package (300) is provided which comprises a first plurality of terminals (303, 304, 305) and a second plurality of terminals (306, 307), which first and second plurality of terminals are exposed outside the encapsulation at a first side of the package. The terminals of the first plurality of terminals (303, 304, 305) are arranged in a first row (301), wherein a distance between each pair of adjacent terminals in the first row (301) is greater or equal than a first threshold value. Furthermore, the terminals of the second plurality of terminals (306, 307) are arranged in a second row (302), wherein a distance between each pair of adjacent terminals in the second row (302) is greater or equal than a second threshold and a distance between the first row (301) and the second row (302) is smaller than at least the first threshold value.
US08067828B2 System for solder ball inner stacking module connection
An integrated circuit package-in-package system including: providing a substrate; mounting a structure over the substrate; supporting an inner stacking module cantilevered over the substrate by an electrical interconnect connected to the substrate, the electrical interconnect forming a gap between the inner stacking module and the structure controlled by the size of the electrical interconnect; and encapsulating the structure and inner stacking module with an encapsulation.
US08067824B2 Integrated circuit module package and assembly method thereof
An integrated circuit module package includes a lead frame having a recessed area. A semiconductor die containing active electrical components is attached to the recessed area of the lead frame. An integrated passive device containing passive electrical components is vertically stacked with, and electrically coupled to, the semiconductor die. An optional heat sink is attached to the integrated passive device. The integrated passive device is connected to the lead frame by conductors to electrically couple the integrated passive device and the semiconductor die to circuitry external to the integrated circuit module package. A cap is then attached to the heat sink or the integrated passive device to protect the semiconductor die and the integrated passive device. The integrated circuit module package dissipates heat from the semiconductor die through the lead frame, and dissipates heat from the integrated passive device through the cap and optional heat sink.
US08067823B2 Chip scale package having flip chip interconnect on die paddle
A flip chip lead frame package includes a die and a lead frame having a die paddle and leads, and has interconnection between the active site of the die and the die paddle. Also, methods for making the package are disclosed.
US08067822B2 Integrated circuit package for semiconductor devices with improved electric resistance and inductance
A semiconductor integrated circuit package having a leadframe (108) that includes a leadframe pad (103a) disposed under a die (100) and a bonding metal area (101a) that is disposed over at least two adjacent sides of the die. The increase in the bonding metal area (101a) increases the number of interconnections between the metal area (101a) and the die (100) to reduce the electric resistance and inductance. Furthermore, the surface area of the external terminals radiating from the package's plastic body (106) is increased if not maximized so that heat can be dissipated quicker and external terminal resistances reduced. The integrated circuit is applicable for MOSFET devices and the bonding metal area (101a) is used for the source terminal (101). The bonding metal area may have a “L” shape, a “C” shape, a “J” shape, an “I” shape or any combination thereof.
US08067819B2 Semiconductor wafer including semiconductor chips divided by scribe line and process-monitor electrode pads formed on scribe line
The present invention discloses a semiconductor wafer having a scribe line dividing the semiconductor wafer into a matrix of plural semiconductor chips. The semiconductor wafer includes a polysilicon layer, a poly-metal interlayer insulation film formed on the polysilicon layer, and a first metal wiring layer formed on the poly-metal interlayer insulation film. The semiconductor wafer includes a process-monitor electrode pad formed on a dicing area of the scribe line. The process-monitor electrode pad has a width greater than the width of the dicing area. The process-monitor electrode pad includes a contact hole formed in the poly-metal insulation film for connecting the first metal wiring layer to the polysilicon layer.
US08067816B2 Techniques for placement of active and passive devices within a chip
A semiconductor die includes a semiconductive substrate layer with first and second sides, a metal layer adjacent the second side of the semiconductive substrate layer, one or more active devices in an active layer on the first side of the semiconductive substrate layer; and a passive device in the metal layer in electrical communication with the active layer. The passive device can electrically couple to the active layer with through silicon vias (TSVs).
US08067811B2 MEMS device, MEMS device module and acoustic transducer
A MEMS device includes a first insulating film formed on a semiconductor substrate, a vibrating film formed on the first insulating film, and a fixed film above the vibrating film with an air gap being interposed therebetween. The semiconductor substrate has a region containing N-type majority carriers. A concentration of N-type majority carriers in a portion of the semiconductor substrate where the semiconductor substrate contacts the first insulating film, is higher than a concentration of N-type majority carriers in the other portion of the semiconductor substrate.
US08067809B2 Semiconductor storage device including a gate insulating film with a favorable nitrogen concentration profile and method for manufacturing the same
A semiconductor storage device with excellent electrical characteristics (write/erase characteristics) by favorable nitrogen concentration profile of a gate insulating film, and a method for manufacturing the semiconductor device. The semiconductor device fabricating method operates by transferring charges through a gate insulating film formed between a semiconductor substrate and a gate electrode, including introducing an oxynitriding species previously diluted by plasma excitation gas into a plasma processing apparatus, generating an oxynitriding species by a plasma, and forming an oxynitride film on the semiconductor substrate as the gate insulating film. The oxynitriding species contains NO gas at a ratio of 0.00001 to 0.01% to the total volume of gas introduced into the plasma processing apparatus.
US08067808B2 Apparatus of memory array using FinFETs
A memory cell includes a FinFET select device and a memory element. In some embodiments a memory cell has a contact element coupled between a surface of the fin and the memory element.
US08067807B2 Semiconductor integrated circuit device
In an LCD driver IC, a high-breakdown-voltage MISFET is mounted together with a typical low-breakdown-voltage MISFET. Because the high-breakdown-voltage MISFET has a gate oxide film thicker than that of the typical MISFET, the electrode of the high-breakdown-voltage MISFET is inevitably high in level. Accordingly, the depth of a gate contact is shallow so that process compatibility with the typical portion is necessary. In the present invention, in, e.g., the channel width direction of the high-breakdown-voltage MISFET, the boundary of a thick-film gate oxide region is located inwardly of the end of a gate electrode. At the gate electrode portion thus lowered in level, a gate contact is disposed so that the boundary of the thick film is located inwardly of the end of the gate electrode and between the gate contact and a channel end.
US08067806B2 Gate structures of CMOS device and method for manufacturing the same
Gate structures of CMOS device and the method for manufacturing the same are provided. A substrate having an NMOS region, a PMOS region, and a work function modulation layer disposed on the NMOS region and the PMOS region is provided. A nitrogen doping process is performed to dope nitrogen into a portion of the work function modulation layer disposed on the PMOS region so as to form an N-rich work function modulation layer disposed on the PMOS region. A nonmetallic conductive layer is formed blanketly covering the work function modulation layer and the N-rich work function modulation layer. A portion of the nonmetallic conductive layer, the work function modulation layer, and the N-rich work function modulation layer is removed to form a first gate in the NMOS region and a second gate in the PMOS region.
US08067805B2 Ultra shallow junction formation by epitaxial interface limited diffusion
A method of forming a field effect transistor creates shallower and sharper junctions, while maximizing dopant activation in processes that are consistent with current manufacturing techniques. More specifically, the invention increases the oxygen content of the top surface of a silicon substrate. The top surface of the silicon substrate is preferably cleaned before increasing the oxygen content of the top surface of the silicon substrate. The oxygen content of the top surface of the silicon substrate is higher than other portions of the silicon substrate, but below an amount that would prevent epitaxial growth. This allows the invention to epitaxially grow a silicon layer on the top surface of the silicon substrate. Further, the increased oxygen content substantially limits dopants within the epitaxial silicon layer from moving into the silicon substrate.
US08067803B2 Memory devices, transistor devices and related methods
A memory device and method of making the memory device. The memory device comprises a storage transistor at a surface of a substrate. The storage transistor comprises a body portion between first and second source/drain regions, wherein the source/drain regions are regions of a first conductivity type. The storage transistor also comprises a gate structure that wraps at least partially around the body portion in at least two spatial planes. A bit line is connected to the first source/drain region and a word line is connected to the gate structure.
US08067802B2 Flexible device and method of manufacturing the same
The rollable device of the invention comprises a substrate of an insulating material (12) with apertures (15) extending from a first to a second side. On the first side switching elements (13) are present, as well as interconnect lines and the like, covered by a coating of organic material (3). On the second side a functional layer is present. Examples of such functional layers include capacitors, antennas and particularly electro-optical layers. Thus, with a rollable display that may include an antenna and a driver circuit is obtained.
US08067801B2 Semiconductor device and method of manufacturing the same
A semiconductor device is provided, which comprises a first transistor and a second transistor formed in a semiconductor layer. The first transistor includes a first source region and a first drain region sandwiching a first gate electrode with the first source region. The second transistor includes an LDD region and a drift region sandwiching the second gate electrode with the LDD region, and a second drain region adjacent to the drift region to sandwich the second gate electrode with the second source region. The first gate electrode has a first sidewall formed on sides thereof and the second gate electrode has a second sidewall formed on sides thereof. The width of the former along the first insulator differs from the width of the latter along the second insulator.
US08067799B2 Semiconductor device having recess channel structure and method for manufacturing the same
A semiconductor device having a recess channel structure includes a semiconductor substrate having a recess formed in a gate forming area in an active area; an insulation layer formed in the semiconductor substrate so as to define the active area and formed so as to apply a tensile stress in a channel width direction; a stressor formed in a surface of the insulation layer and formed so as to apply a compressive stress in a channel height direction; a gate formed over the recess in the active area; and source/drain areas formed in a surface of the active area at both side of the gate.
US08067796B2 Semiconductor component with cell structure and method for producing the same
A semiconductor component comprises a semiconductor body comprising a first component electrode arranged on one of the surfaces of the semiconductor body, a second component electrode arranged on one of the surfaces of the semiconductor body, and a component control electrode arranged on one of the surfaces of the semiconductor body. In this case, active semiconductor element cells are arranged in a first active cell array of the semiconductor body, the semiconductor element cells comprising a first cell electrode, a second cell electrode and a cell control electrode and also a drift path between the cell electrodes. At least the component control electrode is arranged on a partial region of the semiconductor body and a second active cell array is additionally situated in the partial region of the semiconductor body below the component control electrode.
US08067795B2 Single poly EEPROM without separate control gate nor erase regions
A single-poly EEPROM memory device comprises source and drain regions in a semiconductor body, a floating gate overlying a portion of the source and drain regions, which defines a source-to-floating gate capacitance and a drain-to-floating gate capacitance, wherein the source-to-floating gate capacitance is substantially greater than the drain-to-floating gate capacitance. The source-to-floating gate capacitance is, for example, at least about three times greater than the drain-to-floating gate capacitance to enable the memory device to be electrically programmed or erased by applying a potential between a source electrode and a drain electrode without using a control gate. A current path between the source and drain electrodes generally defines current carrying portions of the source and drain regions, and a non-current carrying portion of the source region residing outside the current carrying portion, wherein substantially more of the floating gate overlies the non-current carrying portion than the current carrying portions.
US08067792B2 Memory device with memory cell including MuGFET and FIN capacitor
One embodiment of the present invention relates to a memory cell. The memory cell includes a multi-gate field effect transistor associated with a first region of a semiconductor fin. The memory cell also includes a fin capacitor coupled to a drain of the multi-gate field effect transistor and associated with a second region of the semiconductor fin, where the fin capacitor has an approximately degenerate doping concentration in the second region. Other devices and methods are also disclosed.
US08067790B2 Semiconductor device with less power supply noise
A semiconductor device includes a first power supply line; a second power supply line; a first cell arrangement area in which a first cell is arranged; and a switch area in which a switching transistor and a decoupling capacitance are arranged. The first cell is provided in a first well of a first conductive type, the switching transistor is provided in a second well of the first conductive type, and the decoupling capacitance is provided in a separation area of a second conductive type to separate the first well and the second well from each other. The switching transistor connects the first power supply line and the second power supply line in response to a control signal, the first cell operates with power supplied from the second power supply line, and the decoupling capacitance is connected with the first power supply line.
US08067788B2 Semiconductor device
A semiconductor device includes a substrate common to a first field effect transistor and a second field effect transistor, a channel layer of a first conductivity type formed on the substrate and common to the first and second field effect transistors, a an upper compound semiconductor layer formed on the channel layer and common to the first and second field effect transistors, a compound semiconductor region of a second conductivity type formed in the same layer as the upper compound semiconductor layer, a gate electrode of the first field effect transistor in ohmic contact with the compound semiconductor region, and a gate electrode of the second field effect transistor in Schottky contact with the upper compound semiconductor layer.
US08067787B2 Semiconductor electronic device
A semiconductor electronic device comprises a substrate; a buffer layer formed on the substrate, the buffer layer including not less than two layers of composite layer in which a first semiconductor layer formed of a nitride-based compound semiconductor layer having a lattice constant smaller than a lattice constant of the substrate and a thermal expansion coefficient larger than a thermal expansion coefficient of the substrate and a second semiconductor layer formed of a nitride-based compound semiconductor having a lattice constant smaller than a lattice constant of the first semiconductor layer and a thermal expansion coefficient larger than a thermal expansion coefficient of the substrate are alternately laminated; an intermediate layer provided between the substrate and the buffer layer, the intermediate layer being formed of a nitride-based compound semiconductor having a lattice constant smaller than a lattice constant of the first semiconductor layer and a thermal expansion coefficient larger than a thermal expansion coefficient of the substrate; and a semiconductor active layer formed on the buffer layer, the semiconductor active layer being formed of a nitride-based compound semiconductor, wherein: thicknesses of the first semiconductor layers in the buffer layer are non-uniform thereamong, and at least one of the first semiconductor layer has a thickness greater than a critical thickness, the critical thickness being a thickness above which a direction of warp caused by the first semiconductor layer to the substrate is inverted.
US08067784B2 Semiconductor chip assembly with post/base heat spreader and substrate
A semiconductor chip assembly includes a semiconductor device, a heat spreader, a substrate and an adhesive. The semiconductor device is electrically connected to the substrate and thermally connected to the heat spreader. The heat spreader includes a post and a base. The post extends upwardly from the base into an opening in the adhesive and an aperture in the substrate, and the base extends laterally from the post. The adhesive extends between the post and the substrate and between the base and the substrate. The assembly provides signal routing between a pad and a terminal.
US08067781B2 Light emitting structure and securing device thereof
The light emitting structure disclosed includes a light emitting device, a metal frame, and a repressing fastener. The light emitting device has a plurality of first coupling terminals, and the metal frame has a plurality of second coupling portions. The light emitting device is disposed in the metal frame, and the first coupling terminals touch the second coupling portions to electrically connect the light emitting device and the metal frame. The repressing fastener is disposed on the light emitting device and fastened to the metal frame to secure the light emitting device in the metal frame. An LED securing device is also disclosed.
US08067779B2 Light emitting device with a recess lead portion
A light emitting device includes: a light emitting element; a first lead including a recess in one end portion, the recess including a first bottom surface with the light emitting element bonded thereto, at least one of a through hole and a notch, and a light shielding portion capable of suppressing leakage of emitted light from the light emitting element from the one of the through hole and the notch; a second lead opposed to the first lead; and a molded body filling the one of the through hole and the notch, covering the light emitting element, embedding at least part of the first lead and at least part of the second lead, and made of a translucent resin.
US08067770B2 Thin film transistor and flat panel display device including the same
A thin film transistor includes a channel layer including an amorphous 12CaO.7Al2O3 (C12A7) and a flat panel display device including the same. According to the present invention, the amorphous channel layer can be formed at a low temperature using C12A7. The thin film transistor including the amorphous channel layer has excellent electron mobility.
US08067768B2 Thin-film transistor display panel including an oxide active layer and a nitrogen oxide passivation layer, and method of fabricating the same
Provided is a thin-film transistor (TFT) display panel having improved electrical and reliability properties and a method of fabricating the TFT display panel. The TFT display panel includes gate wiring formed on a substrate; an oxide active layer pattern formed on the gate wiring; data wiring formed on the oxide active layer pattern to cross the gate wiring; a passivation layer formed on the oxide active layer pattern and the data wiring and made of nitrogen oxide; and a pixel electrode disposed on the passivation layer.
US08067767B2 Display substrate having vertical thin film transistor having a channel including an oxide semiconductor pattern
A display substrate according to the present invention comprises a gate line formed on a substrate, a data line, a thin film transistor connected to the gate line and the data line respectively and pixel electrode connected to the thin film transistor, wherein a channel of the thin film transistor is formed in a direction perpendicular to the substrate and, a layer where the channel is formed includes an oxide semiconductor pattern. ON current of thin film transistor of the display substrate can be increased without loss of aperture ratio.
US08067762B2 Resistance random access memory structure for enhanced retention
A bistable resistance random access memory is described for enhancing the data retention in a resistance random access memory member. A dielectric member, e.g. the bottom dielectric member, underlies the resistance random access memory member which improves the SET/RESET window in the retention of information. The deposition of the bottom dielectric member is carried out by a plasma-enhanced chemical vapor deposition or by high-density-plasma chemical vapor deposition. One suitable material for constructing the bottom dielectric member is a silicon oxide. The bistable resistance random access memory includes a bottom dielectric member disposed between a resistance random access member and a bottom electrode or bottom contact plug. Additional layers including a bit line, a top contact plug, and a top electrode disposed over the top surface of the resistance random access memory member. Sides of the top electrode and the resistance random access memory member are substantially aligned with each other.
US08067761B2 Self-aligned memory cells and method for forming
The invention provides a memory cell based on variable resistance material memory element that includes an access device having a pillar structure that may also include a protective sidewall layer. The pillar access device selects and isolates the memory cell from other memory array cells and is adapted to both self-align any memory element formed thereon, and to deliver suitable programming current to the memory element. The pillar structure is formed from one or more access device layers stacked above a wordline and below the memory element. Optional resistive layers may be selectively formed within the pillar structure to minimize resistance in the access device layer and the memory element. The pillar access device may be a diode, transistor, Ovonic threshold switch or other device capable of regulating current flow to an overlying programmable memory material.
US08067756B2 Extreme ultraviolet light source apparatus
In an extreme ultraviolet light source apparatus generating an extreme ultraviolet light from a plasma generated by irradiating a target, which is a droplet D of molten Sn, with a laser light, and controlling the flow direction of ion generated at the generation of the extreme ultraviolet light by a magnetic field or an electric field, an ion collection cylinder 20 is arranged for collecting the ion, and ion collision surfaces Sa and Sb of the ion collection cylinder 20 are provided with or coated with Si, which is a metal whose sputtering rate with respect to the ion is less than one atom/ion.
US08067752B2 Semiconductor testing method and semiconductor tester
A semiconductor testing method capable of quickly counting semiconductor cells in which a seemingly horizontal or vertical line is drawn with a mouse, and raster rotation is performed in alignment with the closer axis. After that, the stage is horizontally moved, pattern matching is performed on an image on a position where the image should be disposed, and an angle is adjusted. The stage is moved evenly along the X-axis and the Y-axis, achieving a movement to a destination like a straight line. In synchronization with the smooth movement of the stage, a cell is surrounded in a rectangular frame by a ruler, and the number of cells is displayed with a numeric value.
US08067751B2 System and method for high resolution field shaping
A system and method are provided for a high resolution radiation treatment system which provide for projecting a field of radiation energy at targeted patient tissue. The system uses a multi-leaf collimator, which is positioned such that a significant clearance is provided between the multi-leaf collimator and the isocenter plane where the targeted tissue is located. The leaves of the multi-leaf collimator are designed to provide for high step resolution in the projected radiation energy shape. Additionally, an embodiment of the system and method herein can provide for a high step resolution in the projected radiation energy shape, and for a dose calculation matrix which has matrix units which coincide with the high step resolution in the projected radiation shape.
US08067749B2 Cleanable helical modules
The invention relates to cleanable spiral modules and a method for production thereof.
US08067748B2 Charged particle beam acceleration and extraction method and apparatus used in conjunction with a charged particle cancer therapy system
The invention comprises a charged particle beam acceleration and optional extraction method and apparatus used in conjunction with charged particle beam radiation therapy of cancerous tumors. Novel design features of a synchrotron are described. Particularly, turning magnets, edge focusing magnets, concentrating magnetic field magnets, and extraction elements are described that minimize the overall size of the synchrotron, provide a tightly controlled proton beam, directly reduce the size of required magnetic fields, directly reduces required operating power, and allow continual acceleration of protons in a synchrotron even during a process of extracting protons from the synchrotron.
US08067744B2 Method and apparatus of detecting ionizing radiation
A method of detecting ionizing radiation is provided. The method includes detecting ionizing radiation using a detector assembly having a pixelated semiconductor substrate, each pixel including a central region and a region of variable response, each pixel further including at least one anode, the detector assembly including a grid electrode coupled to a first surface of the semiconductor substrate such that the grid electrode circumscribes the central region of at least one pixel anode, the detector assembly further including a cathode coupled to a second surface of the semiconductor substrate, the method comprising, measuring a first signal between the at least one pixel anode and the cathode wherein the anode is electrically biased with respect to the cathode, measuring a second signal between the grid electrode and the cathode wherein the grid electrode is electrically biased with respect to the cathode, combining the magnitude of the first signal and the magnitude of the second signal to obtain a total signal from the semiconductor substrate, and outputting the total signal.
US08067743B2 Imaging apparatus and radiation imaging apparatus
Pixels including a photoelectric conversion element 1, a signal transfer TFT (thin film transistor) 2 electrically connected to the photoelectric conversion element, and a reset TFT 3 electrically connected to the photoelectric conversion element and for applying a bias to the photoelectric conversion element are two-dimensionally disposed on the insulating substrate, and the photoelectric conversion element 1, signal transfer TFT 2, and reset TFT 3 are electrically connected through a common contact hole 9. A source or drain electrode of the signal transfer TFT 2 and the source or drain electrode of the reset TFT 3 are formed from a common electroconductive layer.
US08067741B2 Focused pinhole gamma detection device
The invention provides a gamma detection device, a collimator for use therein, and use of such a collimator or device in imaging an object. The invention is directed to pinhole imaging with high energy photons, such as 511 keV photons. In order to achieve sufficiently low pinhole knife edge penetration, the collimator uses a plurality of focused clusters of pinholes, each with a smaller opening angle, and arranged such that all the combined fields of view of the individual pinholes in all clusters provide a large central field of view with still compact dimensions of the detection device. This is made possible since the field of view of a single cluster is divided up into a number of individual fields of view.
US08067733B2 Scanning electron microscope having a monochromator
A scanning electron microscope having a monochromator that can automatically adjust an electron beam entering the monochromator and operating conditions of the monochromator. The scanning electron microscope having a monochromator is equipped with, between an electron source and the monochromator, a first focusing lens for adjusting focusing of the electron beam entering the monochromator and a first astigmatism correcting lens for correcting astigmatism of the electron beam entering the monochromator. The microscope further includes a means of obtaining an image of an electron-beam adjustment sample disposed where the electron beam in the monochromator is focused, and based on the obtained image, driving the first focusing lens and the first astigmatism correcting lens so that the focusing and astigmatism of the electron beam entering the monochromator are adjusted.
US08067729B2 Mass analysis data analyzing apparatus and program thereof
In a mass analysis data analyzing apparatus, centroid data is used as mass spectrum data to be analyzed. First, peaks on the centroid data are specified in order of intensity as a standard peak for identifying an isotopic cluster. The isotopic cluster is detected by comparing an emerging pattern of peaks near the standard peak and an emerging pattern of peaks of an expected isotopic cluster in the case where each valence is assumed. The valence of the determined isotopic cluster is set as the valence of the peaks belonging to the isotopic cluster, and the peak at the forefront of cluster is selected as a monoisotopic peak. With such a mass analysis data analyzing apparatus, it is possible to determine the valence of each peak and identify the monoisotopic peak in a mass spectrum.
US08067725B2 Device and method for displaying image
A deviation of an optic axis of a laser projector is detected, and the deviation is corrected. Laser projector's CPU executes: commanding a laser beam source of one color, out of laser beam sources of three colors, to emit a laser beam; shutting off the laser when sensing that the laser beam is received in a light-receiving region; applying a laser of a color to be detected as to the presence or absence of a deviation of the axis until its reception in the light-receiving region is sensed; keeping time starting when light reception in the light-receiving region is sensed and ending when light reception in a light-receiving region adjacent thereto is sensed; calculating a relative time difference of each of the colors with respect to a reference color; and correcting a light emission timing of the laser beam source of each of the color, based on the calculated time.
US08067723B2 Optical filter
An optical filter includes a light-shielding conductive layer provided with a plurality of apertures on a substrate surface that selectively transmits light of a first wavelength, and a dielectric layer in contact with the conductive layer. A size of the apertures is a size equal to or less than the first wavelength, and a ratio of a surface area of the conductive layer to a surface area of the substrate surface is within a range of equal to or greater than 36% and equal to or less than 74%. A transmissivity of the first wavelength is increased by surface plasmons induced in the apertures by light falling on the conductive layer.
US08067722B2 Method and system for inspecting bottles
The present invention relates to a method for inspecting packagings for a liquid product, such as drinks, including: setting a packaging into rotation, irradiating the packaging during the rotation with a radiation of a predetermined wavelength, making at least one series of at least two recordings of at least a part of the content of the packaging during the rotation, with an image recording device suitable for making recordings at the predetermined wavelength.
US08067719B2 Apparatus and method for capturing and displaying images of the undercarriage of vehicles including one or more scene cameras
A portable undercarriage vehicle inspection system (UVIS) (100) uses an under vehicle imaging (UVI) module (110) to capture an image of the undercarriage of a vehicle. The UVIS also includes multiple scene cameras (120) that capture the associated vehicle scene images. The scene cameras are easy to view and manipulate. The undercarriage image and the associated vehicle scene images are provided to a power and communications unit (PCU) (140) through a network (130) such as Ethernet. These images may be stored in a database repository connected to the network. A notebook computer will serve as an operator workstation (150, 152, 154) for display of real-time, as well as historical, vehicular records. An operator viewing the images can enter additional information related to the images, such as comments and remarks, and archive all of the information for future reference and comparisons.
US08067717B2 Cooking facilitator
A cooking facilitator which is preferably portable and well suited for use as both a timer and cooking process facilitator having particular usefulness with cooking objects which have a characteristic associated with establishing a cooking time such as the weight of a turkey in the case of deep frying a turkey or the thickness of a steak in deep frying the same. A gas flow timer for shutting off an overheated or unattended cooking system is also featured.
US08067716B1 Cooking apparatus
A cooking apparatus includes an outer pot that has a bottom wall and a peripheral wall that is attached to and extends upwardly from the bottom wall. A heating assembly is attached to the outer pot and is adapted for selectively heating the outer pot. An actuator is operationally coupled to the heating assembly for selectively turning the heating assembly on or off. The actuator includes a timer for turning off the heating assembly after a selectable amount of time has expired. An inner pot has a lower wall and a perimeter wall that is attached to and extends upwardly from the lower wall. The inner pot has a size adapted for being removably positionable in the outer pot. The perimeter wall has a plurality of apertures extending therethrough.
US08067714B2 Squeezing detection control method for consumable electrode arc welding
A squeezing detection control method is provided for consumable electrode arc welding. The method includes a step of detecting a droplet squeezing phenomenon by checking that a change in a voltage or resistance between the consumable electrode and base material reaches a squeezing detection reference value, and a step of executing output control for rapidly decreasing a welding current passing through a short-circuited load when the squeezing phenomenon is detected, so that arc re-striking occurs in a state of low current. The squeezing detection reference value is set to a first value during the electrode positive polarity, and set to a second value during the electrode negative polarity. The second value is different from the absolute value of the first value, and each of the first and second values is set such that the resultant welding state is satisfactory.
US08067710B2 Tensioned touch panel and method of making same
A tensioned touch panel includes a support structure having a substrate with a generally planer conductive surface disposed thereon and an insulating spacer generally about the periphery of the substrate. A pretensioned conductive member overlies the support structure. The spacer separates the conductive membrane and the conductive surface thereby to define an air gap therebetween. A conductive membrane is secured to the support structure under sufficient tension to inhibit slack from developing in the conductive membrane as a result of changes in environmental conditions. A method of assembling a tensioned touch panel is also provided.
US08067707B2 Self-calibrating sensor device
A self-calibrating sensor includes a housing, an input lever coupled to the housing and configured to contact a device to be sensed, and an actuating element configured to automatically reposition an output device to a calibrated position. The sensor also includes a cam ring that is configured to move the output device to the calibrated position based on an input received from the actuating element and a lock ring coupled to the input lever. In one exemplary embodiment, the output device is an electrical contact assembly that is slidably engaged with the cam ring. During operation, the cam ring is configured to reposition the electrical contact assembly based on the input received from actuating element.
US08067701B2 I/O connectors with extendable faraday cage
An apparatus providing one or more I/O connections to a computer. The apparatus includes a Faraday cage generally about a flex cable, or other computing element, that may translate when the I/O ports to the computer are utilized. The embodiment maintains the Faraday cage for the flex cable or element as the I/O port housing opens or closes.
US08067699B2 Semiconductor element, method of manufacturing semiconductor element, multi-layer printed circuit board, and method of manufacturing multi-layer printed circuit board
An intermediate layer 38 is provided on a die pad 22 of an IC chip 20 and integrated into a multilayer printed circuit board 10. Due to this, it is possible to electrically connect the IC chip 20 to the multilayer printed circuit board 10 without using lead members and a sealing resin. Also, by providing the intermediate layer 38 made of copper on an aluminum pad 24, it is possible to prevent a resin residue on the pad 24 and to improve connection characteristics between the die pad 24 and a via hole 60 and reliability.
US08067693B2 Bus for high definition multimedia interface
A bus for the high definition multimedia interface (HDMI) is disclosed. The bus comprises a plurality of transmission lines and two clad layers. The conductive lines comprise a plurality of mutually twisted conductor lines arranged in a flat shape. The clad layers are disposed on two opposite surfaces of the twisted conductor lines sandwiching the transmission lines in-between. Since the transmission line sets are arranged in a juxtaposed structure, the bus can be easily bent for routing and coupling to reduce the installation space, streamline the manufacturing process, and reduce the overall manufacturing cost. Furthermore, a continuous extended shield can be used to penetrate or surround a cord set comprised of a group of transmission. Furthermore, the transmission lines may be covered to shield the cord set to protect the signal from external electromagnetic wave interference between the cord sets during the high frequency transmission.
US08067692B2 Cusion grip twist-on wire connector
A twist-on wire connector having a finger friendly cushion cover that covers not only the normal hand gripping region but at least part or all of the normal non-hand gripping region of the twist-on wire connector so that regardless of the way the twist-on wire connector is grasped the user fingers engage the cushion cover to inhibit finger and hand injury and fatigue from repeated securement of twist-on wire connectors as well as twist-on wire connector with enhanced gripping.
US08067689B2 EDM wire
An EDM wire having an outer coating of gamma phase brass with an overlayer of continuous unalloyed zinc or ductile epsilon phase brass entrapping the gamma phase and a process for manufacturing the EDM wire is provided. A second process for synthesizing a ductile epsilon phase brass coating on the aforementioned and other substrates is also provided. The first process includes coating a copper bearing metallic core with zinc. The zinc coating is then converted to gamma phase brass via a diffusion anneal and subsequently re-coated with zinc prior to being cold drawn to its finish diameter.
US08067688B2 Interconnects for solar cell devices
A solar cell assembly comprising a plurality of elongated solar cells, each respective solar cell comprising (i) a core configured as a first electrode, (ii) a semiconductor junction circumferentially disposed on the core, (iii) a transparent conductive oxide (TCO) layer disposed on the semiconductor junction, and (iv) an elongated counter-electrode disposed lengthwise on a first side of the respective solar cell and extending outward from the TCO layer. On a second side of each cell, approximately opposite the counter-electrode, is a notch or other disruption extending through the semiconductor junction and the transparent oxide layer, thereby exposing the core of the solar cell. The solar cell assembly may further comprise conductive internal reflectors configured between a first and second elongated solar cell in the plurality of solar cells such that a portion of the solar light reflected from the respective internal reflector is reflected onto the solar cells.
US08067687B2 High-efficiency, monolithic, multi-bandgap, tandem photovoltaic energy converters
A monolithic, multi-bandgap, tandem solar photovoltaic converter has at least one, and preferably at least two, subcells grown lattice-matched on a substrate with a bandgap in medium to high energy portions of the solar spectrum and at least one subcell grown lattice-mismatched to the substrate with a bandgap in the low energy portion of the solar spectrum, for example, about 1 eV.
US08067686B2 Thermoelectric material and thermoelectric element
Disclosed is a thermoelectric material which is represented by the following composition formula (1) or (2) and comprises as a major phase an MgAgAs type crystal structure: (Tia1Zrb1Hfc1)xNiySn100-x-y  composition formula (1); (Lnd(Tia2Zrb2Hfc2)1-d)xNiySn100-x-y  composition formula (2); (wherein a1, b1, c1, x and y satisfy the conditions of: 0
US08067685B2 Stringed instrument utilizing sympathetic vibrations
Embodiments of the present invention relate to a musical instrument having a plurality of strings, wherein a global fundamental tone produces a sympathetic resonance in one or more of the plurality of strings. In accordance with one embodiment of the present invention, a stringed musical instrument comprises a plurality of strings, and a vibration inducing device configured to create a global fundamental tone upon demand by a user, wherein at least a first string of the plurality of strings controllably produces a sympathetic resonance in response to the global fundamental tone.
US08067683B2 Method and apparatus for electronically sustaining a note from a musical instrument
A sensed signal corresponding to a note played on a musical instrument is electronically sustained by electronically combining the sensed signal with a synthesized signal whenever a sustain control switch is activated. The set of characteristics of the synthesized signal are, initially, substantially the same as the set of characteristics of the sensed signal, but may be varied over time.
US08067677B2 Soybean cultivar 8029288
A soybean cultivar designated 8029288 is disclosed. The invention relates to the seeds of soybean cultivar 8029288, to the plants of soybean 8029288, to plant parts of soybean cultivar 8029288, and to methods for producing a soybean plant produced by crossing soybean cultivar 8029288 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars, or breeding cultivars, and plant parts derived from soybean variety 8029288, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar 8029288, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing the cultivar 8029288 with another soybean cultivar.
US08067675B1 Soybean variety XB32E09
According to the invention, there is provided a novel soybean variety designated XB32E09. This invention thus relates to the seeds of soybean variety XB32E09, to the plants of soybean XB32E09 to plant parts of soybean variety XB32E09 and to methods for producing a soybean plant produced by crossing plants of the soybean variety XB32E09 with another soybean plant, using XB32E09 as either the male or the female parent.
US08067674B2 Desaturase genes, enzymes encoded thereby, and uses thereof
Disclosed are isolated polynucleotides encoding an omega-3 desaturase and a delta-12 desaturase, the enzymes encoded by the isolated polynucleotides, vectors containing the isolated polynucleotides, transgenic hosts that contain the isolated polynucleotides that express the enzymes encoded thereby, methods for producing the desaturase enzymes, and method of using the enzymes to make polyunsaturated fatty acids. The isolated polynucleotides are derived from a fungus, Saprolegnia diclina (ATCC 56851). In particular, omega-3-desaturase may be utilized, for example, in the conversion of arachidonic acid (AA) to eicosapentaenoic acid (EPA). Delta-12 desaturase may be used, for example, in the conversion of oleic acid (OA) to linoleic (LA). EPA or polyunsaturated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
US08067669B2 Method for inducing resistance to fungal infection in transgenic plants using plant defense peptides
A method for the identification of peptides having an affinity for the surface of fungi is provided as is a method for the identification of peptides capable of affecting the development of a fungus. Also provided are compositions comprising peptides identified using the method of the present invention. In addition, isolated polynucleotides, vectors, expression cassettes and transformed cells capable of expressing peptides identified by the method of the present invention are provided. Such polynucleotides, vectors, expression cassettes may be introduced into and confer upon plants the capability to resist fungal infection.
US08067667B2 Dominant gene suppression transgenes and methods of using same
Pairs of plants are provided in which complementing constructs result in suppression of a parental phenotype in the progeny. Methods to generate and maintain such plants and methods of use of such plants, are provided, including use of parental plants to produce sterile plants for hybrid seed production. Also provided are methods for maintaining a homozygous recessive condition and for repressing transmission of transgenes.
US08067663B2 Absorbent sanitary article for absorbing body fluid
Disclosed is an absorbent sanitary article for absorbing body fluids which comprises a matrix containing metallic silver, wherein the silver is present bound to a fiber 24 exclusively on the surface thereof.
US08067654B2 Transition metal catalysts
Transition metal catalysts comprise (a) a source of a Group 3 to 10 transition metal, (b) a ligand having the formula: R1R2X—Y—XR3R4 wherein X is phosphorus, arsenic or antimony, Y is a bridging group having the formula: Z-(A)-D-Rm wherein Z is the moiety linking the X groups, A is a linear or cyclic hydrocarbyl, substituted hydrocarbyl, heterohydrocarbyl or substituted heterohydrocarbyl linking group wherein the number of atoms directly linking Z to D is 1, 2 or 3, D is N, P, As, O, S or Se, R is hydrogen, alkyl, hydrocarbyl, substituted hydrocarbyl, heteroalkyl, heterohydrocarbyl or substituted heterohydrocarbyl, and m is 1 or 2, R1, R2, R3, and R4 are the same or different and represent hydrocarbyl or functionalized hydrocarbyl moieties with the proviso that if D is nitrogen, R is not a cyclic ether, and optionally an activator. The transition metal catalysts are suitable for the selective trimerisation or tetramerisation of olefins in particular ethylene.
US08067652B2 Processes for controlling the viscosity of polyalphaolefins
The invention relates to a process for forming a polyalphaolefin, the process comprising the step of polymerizing at least one C8-C12 monomer, preferably a decene such as 1-decene, in the presence of an aluminoxane, an activator and a metallocene to form the polyalphaolefin, wherein the molar ratio of the aluminoxane to the metallocene is less than 250:1. The invention also relates to a process for forming a polyalphaolefin having a desired kinematic viscosity from at least one monomer in the presence of an aluminoxane, an organoboron compound and a metallocene. The process comprises the steps of, inter alia, providing a correlation between (i) the molar ratio of the aluminoxane to at least one of the organoboron compound and the metallocene, and (ii) the kinematic viscosity of the polyalphaolefin to form polyalphaolefins having predictable viscosities.
US08067650B2 Process for the production of HFO trans-1234ze from HFC-245fa
This invention relates a process for the manufacture of the HFO trans-1,3,3,3-tetrafluoropropene (HFO trans-1234ze). More particularly, the invention pertains to a process for the manufacture of the HFO trans-1234ze by first dehydrofluorinating 1,1,1,3,3-pentafluoropropane to thereby produce a mixture of cis-1,3,3,3-tetrafluoropropene, trans-1,3,3,3-tetrafluoropropene and hydrogen fluoride. Then optionally recovering hydrogen fluoride and then recovering trans-1,3,3,3-tetrafluoropropene.
US08067649B2 Method for producing fluorinated organic compounds
Disclosed is a process for producing tetrafluoropropene comprising: (a) catalytically fluorinating at least one tetrafluoropropene in a first reactor to produce HCFO-1233xf; (b) reacting said HCFO-1233xf with hydrogen fluoride in a second reactor to produce HCFC-244bb; (c) recycling at least a portion of said HCFC-244bb back to said first reactor as recycled HCFC-244bb; and (d) catalytically dehydrochlorinating said recycled HCFC-244bb in said first reactor to produce HFO-1234yf.
US08067648B2 Method for synthesizing radioactive ligand having 18F-labeled fluorobenzene ring
A phenyl tin compound is synthesized by using a derivative having various functional groups and a bromo- or iodo-benzene ring as a labeling material of a radioactive ligand. On the other hand, a novel hydroxytosyl iodobenzene compound having an electron-donating group is obtained by oxidizing iodobenzene having one or more electron-donating groups and reacting it with tosylic acid. Then, a diphenyliodonium salt which is a labeling precursor is synthesized by reacting the resulting compound with various phenyl tin compounds. Finally, a 18F-labeled ligand having various functional groups and a [18F] fluorobenzene ring is synthesized by reacting the resulting diphenyliodonium salt with [18F]F−.
US08067644B2 Process for conducting an organic reaction in ionic liquids
The present disclosure describes processes for producing cyclohexenes using Lewis acidic ionic liquids comprising the steps of providing to a reactor an α,β-unsaturated carbonyl dienophile, providing to the reactor a 1,3-diene, providing a Lewis acidic ionic liquid to the reactor; and reacting the α,β-unsaturated carbonyl dienophile with 1,3-diene to form a substituted cyclohexene product. The α,β-unsaturated carbonyl dienophile can be mesityl oxide, the 1,3-diene can be piperylene; and the Lewis acidic ionic liquid can be AlCl3:[C2mim]Cl; AlCl3:[C8mim]Cl; or mixtures thereof.
US08067641B2 Synthesis of triethylenetetramines
Methods and intermediates for synthesizing triethylenetetramine and salts thereof, as well as novel triethylenetetramine salts and their crystal structure, and triethylenetetramine salts of high purity.
US08067637B2 Contrast agents
The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds. More specifically the iodine containing compounds are chemical compounds containing a hydrophilic aliphatic central moiety allowing for the arrangement of three iodinated phenyl groups bound thereto. The invention also relates to the use of such diagnostic compositions as contrast agents in diagnostic imaging and in particular in X-ray imaging and to contrast media containing such compounds.
US08067636B2 Dihydrazide compounds, preparation and uses thereof
Disclosed are dihydrazide compounds having formula (I) or (II), wherein R1-R4 are alkylene, substituted alkylene, aryl or polyether radical. The preparation and uses for producing medical hydrogel and medicine controlled releasing carrier of said dihydrazide compounds are provided.
US08067630B1 T-butyl cascade polymers
A method for forming cascade polymers specifically utilizing the amine monomer of the formula The monomer is made by initially reacting nitromethane and CH2═CHCO2—TBu by nucleophilic addition to form the triester nitrotrialkanoate of the formula and then reducing the nitrosubstituent to afford the said amine monomer.
US08067629B2 Dispersant antifoulant for acrylonitrile
A styrene sulfonate polymer which is highly effective at preventing fouling of equipment used in the manufacturing process of acrylonitrile. The styrene sulfonate polymer is particularly effective when introduced into the quench column, the recovery stage and the wastewater processing section of the acrylonitrile manufacturing process.
US08067628B2 Water-soluble binuclear nitrosyl iron complexes with natural aliphatic thiolyls possessing cytotoxic, apoptotic and no-donor activity
The present invention relates to water-soluble binuclear cationic nitrosyl iron complexes with natural aliphatic thiolyls of general formula [Fe2(SR)2(NO)4]SO4, wherein R is sulfur-containing aliphatic ligands of natural origin, preferably, cystamine or penicillamine, to a method for the preparation thereof, to use thereof as an anticancer agent, to an apoptosis inducer, to a pharmaceutical composition comprising said complexes in an effective amount, and to a kit useful for the treatment of cancer diseases.
US08067626B2 Processes for polymeric precursors for CAIGS silver-containing photovoltaics
This invention relates to processes for compounds, polymeric compounds, and compositions used to prepare semiconductor and optoelectronic materials and devices including thin film and band gap materials. This invention provides a range of compounds, polymeric compounds, compositions, materials and methods directed ultimately toward photovoltaic applications, transparent conductive materials, as well as devices and systems for energy conversion, including solar cells. In particular, this invention relates to polymeric precursor compounds and precursor materials for preparing photovoltaic layers. A compound may contain repeating units {MB(ER)(ER)} and {MA(ER)(ER)}, wherein MA is a combination of Cu and Ag, each MB is In or Ga, each E is S, Se, or Te, and each R is independently selected, for each occurrence, from alkyl, aryl, heteroaryl, alkenyl, amido, silyl, and inorganic and organic ligands.
US08067625B2 Fluorosurfactants
The present invention relates to fatty acid esters of polyols or sulfonated fatty acid esters or sulfonated fatty acid amides containing at least one group Y, where Y stands for CF3—(CH2)a—O—, SF5—, CF3—(CH2)a—S—, CF3CF2S—, [CF3—(CH2)a]2N— or [CF3—(CH2)a]NH—, where a stands for an integer selected from the range from 0 to 5, or formula (I), where Rf stands for CF3—(CH2)r—, CF3—(CH2)r—O—, CF3—(CH2)r—S—, CF3CF2—S—, SF5—(CH2)t— or [CF3—(CH2)r]2N—, [CF3—(CH2)r]NH— or (CF3)2N—(CH2)r—, B stands for a single bond, O, NH, NR, CH2, C(O)—O, C(O), S, CH2—O, O—C(O), N—C(O), C(O)—N, O—C(O)—N, N—C(O)—N, O—SO2 or SO2—O, R stands for alkyl having 1 to 4 C atoms, b stands for 0 or 1 and c stands for 0 or 1, q stands for 0 or 1, where at least one radical from b and q stands for 1, and r stands for 0, 1, 2, 3, 4 or 5, to processes for the preparation of these compounds, and to uses of these surface-active compounds.
US08067620B2 Dispiro 1,2,4-trioxolane antimalarials
A means and method for treating malaria, schistosomiasis, and cancer using a spiro or dispiro 1,2,4-trioxolane is described. The preferred 1,2,4-trioxolanes include a spiroadamantane group on one side of the trioxolane group, and a spirocyclohexyl on the other side of the trioxolane group. In comparison to artemisinin semisynthetic derivatives, the compounds of this invention are structurally simple, easy to synthesize, non-toxic, and potent against malarial parasites. The compounds of the invention unexpectedly provide a single-dose cure for malaria, as well as prophylactic activity against the same. The compounds are also active against schistosomiasis and cancer.
US08067617B2 Indolinone derivatives and process for their manufacture
The present invention relates to specific indolinone derivatives, namely the compounds of formula, in which R1 represents an hydrogen atom or a group, and R2 and R3 each represent an hydrogen atom or R2 and R3 taken together represent a group, with the proviso that when R1 represents an hydrogen atom R2 and R3 taken together represent a group, and to a process for their manufacture.
US08067612B2 Method for producing bisbenzoxazoles
The invention relates to a method for producing bisbenzoxazoles that are interconnected by means of a system of conjugated double bonds, according to which o-aminophenols are reacted with dicarboxylic acids, the carboxyl groups of which are interconnected via a double bond or a system of conjugated double bonds, to form an ammonium salt, said ammonium salt being converted in the presence of dehydrogenating catalysts and solvents with a low dielectric loss into benzoxazol by means of microwave radiation.
US08067609B2 Methods for oligomerizing olefins with chromium pyridine thioether catalysts
The present invention provides a method of producing oligomers of olefins, comprising reacting olefins with a chromium based catalyst under oligomerization conditions. The catalyst can be the product of the combination of a chromium compound and a pyridyl thioether compound. In particular embodiments, the catalyst compound can be used to trimerize or tetramerize ethylene to 1-hexene, 1-octene, or mixtures of 1-hexene and 1-octene.
US08067605B2 Process for production of piperidine derivatives
Processes are disclosed for preparing piperidine derivative compounds of the formulae I, II or III: The processes involve reacting a compound of formula Ia, IIa or IIIa with isobutyrate or an isobutyrate equivalent.
US08067602B2 Asymmetric cyanine fluorescent dyes, compositions and their use in staining biological samples
Asymmetric cyanine fluorescent dyes are represented by general formula I. These kinds of dyes may be used as a staining agent for nucleic acids, with the spectra at 600-900 nm in the near-infrared region and without interference from background fluorescence. These kinds of dyes may be useful with small-type red semiconductor lasers as the light source (such as 633 nm). Compositions comprising these dyes and methods for staining biological samples using these dyes or compositions are also provided.
US08067600B2 Histone deacetylase inhibitors and methods of use thereof
One aspect of the invention relates to HDAC inhibitors. Methods of sensitizing a cancer cell to the cytotoxic effects of radiotherapy are also provided. The invention also provides methods for treating cancer and methods for treating neurological diseases. Additionally, the invention further provides pharmaceutical compositions comprising an HDAC inhibitor of the invention, and kits comprising a container containing an HDAC inhibitor of the invention.
US08067599B2 Imidazo [4,5-B] pyridine and pyrrolo [2,3-B] pyridine protein kinase inhibitors
Objects of the present invention are the compounds of formula I their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
US08067597B2 Synthetic route to 14-hydroxyl opiates through 1-halo-thebaine or analogs
Novel methods of synthesis of known and novel 14-hydroxyl opiates through 1-halothebaine and derivatives are described.
US08067595B2 Process for producing tricyclic ketone
In order to efficiently supply CPT, which is a starting compound of irinotecan hydrochloride and a variety of camptothecin derivatives, by a practical total synthesis, the invention provides a means of efficiently preparing a tricyclic ketone that corresponds to a CDE ring moiety of a camptothecin (CPT) skeleton.
US08067590B2 Pyridone derivates with MCH antagonistic activity and medicaments comprising these compounds
The present invention relates to compounds of general formula I wherein the groups and radicals B, k, L, U, V, W, X, Y, Z, R1, R2, have the meanings given in claim 1. Moreover the invention relates to pharmaceutical compositions containing at least one compound according to the invention. By virtue of their MCH-receptor antagonistic activity the pharmaceutical compositions according to the invention are suitable for the treatment of metabolic disorders and/or eating disorders, particularly obesity, bulimia, anorexia, hyperphagia and diabetes.
US08067588B2 Insecticidal (1,3,5)-triazinyl phenyl hydrazones
(1,3,5)-Triazinyl phenyl hydrazones are effective at controlling insects.
US08067586B2 Fused heteroaryl derivatives
The present invention provides a pharmaceutical composition which is useful as a phosphatidylinositol 3 kinase (PI3K) inhibitor and an antitumor agent, and it provides a novel bicyclic or tricyclic fused heteroaryl derivative or a salt thereof which possesses an excellent PI3K inhibiting activity and cancer cell growth inhibiting activity.
US08067583B2 Method for synthesizing furanosteroids
The present invention is a method for synthesizing furanosteroids. The method involves intramolecular Diels-Alder/retro-Diels-Alder reaction and tautomerization of a functionalized alkyne oxazole to produce a furo[2,3-b]phenol derivative which is elaborated by intermolecular and intramolecular condensations to generate ring-A of the furanosteroid. Furanosteroids and pharmaceutical compositions containing the same are also provided.
US08067582B2 Fused heterocyclic compounds useful as modulators of nuclear hormone receptor function
Disclosed are fused heterocyclic compounds of Formula (I) or pharmaceutically-acceptable salts or stereoisomers thereof. Also disclosed are methods of using such compounds in the treatment of at least one androgen receptor-associated condition, such as, for example, cancer, and pharmaceutical compositions comprising such compounds.
US08067580B2 Isolation of DNA, RNA and protein from a single sample
The invention provides a method for the separation and purification of two or three cellular components selected from genomic DNA, RNA and proteins from a single biological sample. The method comprises generating an aqueous solution containing the cellular components by lysing cells with a lysis solution; contacting the aqueous solution with an ion exchanger for genomic DNA and RNA to bind to the ion exchanger; collecting the flow-through which contains unbound proteins; eluting RNA from the ion exchanger; and eluting DNA from the ion exchanger. For the purification of any two of the cellular components, one of the components is not collected. The invention also provides reagent kits for carrying out the methods.
US08067579B2 Nucleic acid extraction method
The present invention relates to a method for isolating nucleic acids from a nucleic acid containing sample, and a kit for carrying out said method. More specifically, it relates to a novel method for extracting nucleic acids from a nucleic acid containing sample, using an anion exchange solid support, and allowing this solid phase with the nucleic acid bound thereto to react with a compound which is also capable of binding to said anion exchange solid support and which optionally provides additional charges at the surface of the anion exchange solid material, thereby preferably changing the surface charge density of the solid support and then releasing the nucleic acid from the solid support, eliminating the need for high salt and/or high pH elution buffers.
US08067577B2 Methods and compositions for the treatment of intestinal conditions
Methods and compositions for the treatment of intestinal disorders, such as IBD and Crohn's disease, are disclosed. Preferred compositions include siNA. Also disclosed is a method of specifically targeting siNA to treat intestinal disorders by intrarectal administration of siNA compounds.
US08067575B2 RNA interference mediated inhibition of cyclin D1 gene expression using short interfering nucleic acid (siNA)
This invention relates to compounds, compositions, and methods useful for modulating cyclin (e.g., cyclin D1) and/or cyclin dependent kinase (CDK) gene expression using short interfering nucleic acid (siNA) molecules. This invention also relates to compounds, compositions, and methods useful for modulating the expression and activity of other genes involved in pathways of cyclin (e.g., cyclin D1) and/or cyclin dependent kinase (CDK) gene expression and/or activity by RNA interference (RNAi) using small nucleic acid molecules. In particular, the instant invention features small nucleic acid molecules, such as short interfering nucleic acid (siNA), short interfering RNA (siRNA), double-stranded RNA (dsRNA), micro-RNA (miRNA), and short hairpin RNA (shRNA) molecules and methods used to modulate the expression of cyclin (e.g., cyclin D1) and/or cyclin dependent kinase (CDK) genes.
US08067574B2 Nucleic acid agents for downregulating H19, and methods of using same
Isolated oligonucleotides capable of down-regulating H19 mRNA in cancer cells are disclosed, as well as pharmaceutical compositions that include the oligonucleotides and methods of treatment of cancer using them. Methods of treating cancer comprising administering agents capable of downregulating H19 mRNA in combination with an additional anti-cancer treatment are further disclosed.
US08067570B2 Therapeutic uses of inhibitors of RTP801
The present invention provides novel molecules, compositions, methods and uses for treating microvascular disorders, eye diseases respiratory conditions and hearing disorders based upon inhibition of the RTP801 gene and/or protein.
US08067568B2 Method for diagnosing spinal muscular atrophy
A method for diagnosing spinal muscular atrophy is provided. The method includes providing a biological sample of a subject containing a nucleotide of SMN gene, amplifying SMN exons 1, 2a, 2b, 3, 4, 5, 6, 7, and 8 by a universal multiplex PCR using the nucleotide as a template and the primers to obtain fragments of the SMN exons 1, 2a, 2b, 3, 4, 5, 6, 7, and 8, labeling the fragments of the SMN exons 1, 2a, 2b, 3, 4, 5, 6, 7, and 8 by a fluorescent primer to obtain fluorescence-labeled exon fragments, and analyzing the fluorescence-labeled exon fragments by a capillary electrophoresis. If the SMN1/SMN2 ratios in exon 7 and 8 are different, it indicates that the subject is susceptible to spinal muscular atrophy. Additionally, if the peak of certain exon fragment appears crossed, it indicates an intragenic mutation in the exon.
US08067566B2 Dengue serotype 2 attenuated strain
The invention relates to live attenuated VDV2 (VERO-Derived Vaccine Dengue serotype 2) strains which have been derived from the wild-type dengue-2 strain 16681 by passaging on PDK and Vero cells and nucleic acids thereof. The invention further relates to a vaccine composition which comprises a VDV2 strain.
US08067564B2 Methods of obtaining a specific binding member that binds eotaxin
Specific binding members directed to eotaxin-1, in particular human antibodies and antibody fragments against human eotaxin-1 and especially those which neutralize eotaxin-1 activity. The antibodies VH and/or VL domain of the scFv fragment herein termed CAT-212 and of the IgG4 antibody herein termed CAT 213. One or more complementary determining regions (CDRs) of the CAT-212/-213 VH and/or VL domains, especially VH CRD3 in other antibody framework regions. Compositions containing specific binding members, and their use in methods of inhibiting or neutralizing eotaxin, including methods of treatment of the human or animal body by therapy.
US08067563B2 Tumor suppressor gene, p471NG3
The invention provides isolated nucleic acid and amino acid sequences of novel human tumor suppressors, antibodies to such tumor suppressors, methods of detecting such nucleic acids and proteins, methods of screening for modulators of tumor suppressors, and methods of diagnosing and treating tumors with such nucleic acids and proteins.
US08067560B2 SRSV detection kit
This invention relates to an SRSV detection kit comprising all antibodies against SRSV-related virus constituting peptides selected from the following peptide groups (a) to (k), respectively: (a) a peptide having an amino acid sequence represented by SEQ ID NO: 1, and the like, (b) a peptide having an amino acid sequence represented by SEQ ID NO: 2, and the like, (c) a peptide having an amino acid sequence represented by SEQ ID NO: 3, and the like, (d) a peptide having an amino acid sequence represented by SEQ ID NO: 4, and the like, (e) a peptide having an amino acid sequence represented by SEQ ID NO: 5, and the like, (f) a peptide having an amino acid sequence represented by SEQ ID NO: 6, and the like, (g) a peptide having an amino acid sequence represented by SEQ ID NO: 7, and the like, (h) a peptide having an amino acid sequence represented by SEQ ID NO: 8, and the like, (i) a peptide having an amino acid sequence represented by SEQ ID NO: 9, and the like, (j) a peptide having an amino acid sequence represented by SEQ ID NO: 10, and the like, and (k) a peptide having an amino acid sequence represented by SEQ ID NO: 11, and the like.Use of the kit makes it possible to detect most SRSV-related viruses and further to distinguish their serotypes and genogroups, easily and surely.
US08067559B2 Yeast-based vaccines as immunotherapy
Compositions and methods for treating and/or preventing a variety of diseases and conditions that are amenable to immunotherapy and, in one particular embodiment, compositions and methods for treating and/or preventing cancer in an animal are described. Specifically improvements related to the use of a yeast-based vaccine comprising a yeast vehicle and an antigen that is selected to elicit an antigen-specific cellular and humoral immune response in an animal, for use in prophylactic and/or therapeutic vaccination and the prevention and/or treatment of a variety of diseases and conditions are disclosed.
US08067557B2 OCL-2A3 compositions and uses thereof
This invention relates to osteoclast-specific genes and proteins. Specifically, the invention relates to OCL-2A3 or Atp6v0d2, the gene encoding it and uses thereof in methods and treatment of bone disorders.
US08067554B2 Ion exchange chromatography of GLP-1, analogs and derivatives thereof
The present invention relates to an ion exchange chromatography process for purifying GLP-1 or an analog or a derivative thereof from a mixture containing said GLP-1 and related impurities, and to an industrial method including such ion exchange chromatography process.
US08067549B2 Humanized antibodies and compositions for binding sphingosine-1-phosphate
The present invention relates to anti-S1P agents, particularly humanized monoclonal antibodies (and antigen binding fragments thereof) specifically reactive with S1P, compositions containing such antibodies (or fragments), and the use of such antibodies (or fragments), for example, to treat diseases and conditions associated with aberrant levels of S1P.
US08067548B2 Fusion proteins having mutated immunoglobulin hinge region
A fusion protein having a non-immunoglobulin polypeptide having a cysteine residue proximal to the C terminal thereof, and an immunoglobulin component with a mutated hinge region is provided. The mutation comprises a point mutated site corresponding in position to the position in a native hinge region of the cysteine residue located nearest the cysteine residue of the non-Ig component. The distance from the cysteine residue of the non-immunoglobulin polypeptide and any remaining cysteine residues of the mutated hinge region is sufficient to prevent the formation of a disulphide bond therebetween.
US08067546B2 Humanized anti-CD70 binding agents and uses thereof
Disclosed are CD70 binding agents, such as humanized anti-CD70 antibodies and fragments and derivatives, that exert a cytotoxic, cytostatic or immunomodulatory on CD70 expressing cells, as well as pharmaceutical compositions and kits comprising the antibody, fragment or derivative. Also disclosed are methods for the treatment of CD70-expressing cancers and immunological disorders, comprising administering to a subject the CD70 binding agents or pharmaceutical compositions.
US08067545B2 Isolated antibodies against biologically active leptin-related peptides
The present invention relates to methods and compositions containing novel leptin peptides, preferably for the modulation of body mass (i.e., weight), more specifically for novel diagnostic and therapeutic applications in homeostasis of body weight and adipose tissue mass.
US08067543B2 Factor VIII polymer conjugates
The invention is a proteinaceous construct comprising a Factor VIII molecule which is conjugated to a water-soluble polymer via carbohydrate moieties of Factor VIII, and methods of preparing same.
US08067541B2 Highly thermostable fluorescent proteins
Thermostable fluorescent proteins (TSFPs), methods for generating these and other stability-enhanced proteins, polynucleotides encoding such proteins, and assays and method for using the TSFPs and TSFP-encoding nucleic acid molecules are provided. The TSFPs of the invention show extremely enhanced levels of stability and thermotolerance. In one case, for example, a TSFP of the invention is so stable it can be heated to 99° C. for short periods of time without denaturing, and retains 85% of its fluorescence when heated to 80° C. for several minutes. The invention also provides a method for generating stability-enhanced variants of a protein, including but not limited to fluorescent proteins.
US08067539B2 T1R taste receptors and genes encoding same
Newly identified mammalian taste-cell-specific G protein-coupled receptors, and the genes and cDNA encoding said receptors are described. Specifically, T1R G protein-coupled receptors active in taste signaling, and the genes and cDNA encoding the same, are described, along with methods for isolating such genes and for isolating and expressing such receptors. Methods for representing taste perception of a particular taste stimulus in a mammal are also described, as are methods for generating novel molecules or combinations of molecules that elicit a predetermined taste perception in a mammal, and methods for simulating one or more tastes. Further, methods for stimulating or blocking taste perception in a mammal are also disclosed.
US08067537B2 Composition and method for treatment of stomatitis
A composition and a method effective in preventing or treating stomatitis are presented. The composition contains glutathione or a pharmaceutically acceptable salt thereof and/or orotic acid or a derivative thereof or a pharmaceutically acceptable salt thereof is provided.
US08067529B2 Immunogenic T-helper epitopes from human tumour antigens and immunotherapeutic methods using said epitopes
The present invention relates to immunotherapeutic methods, and molecules and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer, in particular renal cancer. The present invention furthermore relates to tumour-associated T-helper cell peptide epitopes, alone or in combination with other tumour-associated peptides, that serve as active pharmaceutical ingredients of vaccine compositions which stimulate anti-tumour immune responses. In particular, the present invention relates to 338 novel peptide sequences derived from HLA class II molecules of human tumour cell lines which can be used in vaccine compositions for eliciting anti-tumour immune responses.
US08067527B2 Polyamic acid and polyimide
A polyamic acid comprising at least 10 mol % repeating units represented by the formula [1] or [2]; and a polyimide represented by the formula [3] or [4] which is obtained from the polyamic acid. A polyimide film having high heat resistance and satisfactory in light-transmitting properties and tensile strength is obtained from the polyamic acid. (In the formulae, R1 and R2 each independently represents hydrogen or C1-10 alkyl; R3 and R4 each independently represents hydrogen, halogeno, C1-10alkyl, or phenyl or the R3 and R4 on adjoining carbon atoms are bonded to each other to form C3-8 cycloalkyl or phenyl; R5 represents a divalent organic group; and n is an integer of 2 or larger.)
US08067524B2 Use of hydrophobically modified polyaminamides with polyethylene glycol esters in paper products
The present invention uses hydrophobically modified polyaminamide with standard wet strength agent to produce a softer and more absorbent paper material. The hydrophobically modified polyaminamide is substantive to cellulosic fibers, thus is able to carry polyethylene glycol esters or ethers, a non-substantive material to cellulosic fiber as stable complexes, into the paper product.
US08067522B2 Low viscosity, alkoxysilane-functional prepolymers and a process for their preparation
The present invention relates to a process for preparing alkoxysilane-functional prepolymers by reacting A) 1.0 equivalent of a polyol component have a number average molecular weight of 3000 g/mol to 20,000 g/mol and containing one or more polyoxyalkylene polyols or polyoxyalkylene polyol prepolymers with B) 1.05 to 1.50 equivalent of an isocyanate- and alkoxysilane-functional compound of formula I) wherein X, Y, and Z independently of one another are linear or branched C1-C8 alkyl or C1-C8 alkoxy radicals, wherein at least one of the radicals is a C1-C8 alkoxy group and R is an organic radical having a functionality of at least two, and subsequently further reacting the remaining free NCO groups by allophanatization or by reaction with C) an isocyanate-reactive component. The present invention also relates to the alkoxysilane-functional prepolymers obtained by the process of the invention.
US08067515B2 Method of producing an acrylic acid-based polymer
Disclosed is a method for producing a polymer through living polymerization, comprising forming an oligomer having a polymerization active end, which is an oligomer higher than an average 1.0-mer and lower than an average 4.0-mer or an average 4.0-mer, and polymerizing using the oligomer having a polymerization active end as an initiating species, wherein the acrylic acid-based polymer comprising a repeating unit derived from a poly(α-lower alkyl)acrylate, and a repeating unit derived from an (α-lower alkyl)acrylic ester represented by formula (I) wherein R1 represents a hydrogen atom or a lower alkyl group, and R2 represents an organic group having a polar group in an arm portion.
US08067513B2 Styrenated phenol ethoxylates in emulsion polymerization
The present invention relates to the use of Styrenated Phenol Ethoxylates as surfactants in emulsion polymerization. The present invention further relates to the use of both anionic and nonionic Styrenated Phenol Ethoxylates in emulsion polymerization. Latexes with small average particle and narrow particle size distributions are obtained. Prepared latexes also have low coagulum levels and exhibit excellent mechanical and chemical stability.
US08067511B2 Ethylene copolymer and a method of preparing the same
Provided are ethylene copolymers and a process for preparing the same. More specifically, provided are ethylene copolymers exhibiting excellent processibility and physical properties due to its multimodal molecular weight distribution index, through a multi-stage process by using reactors connected in series or in parallel in the presence of catalyst composition containing transition metal catalyst, and a process for preparing the same.
US08067509B2 Reactor systems and processes for using the same
A process for the polymerization of olefin's, including: introducing an olefin and a polymerization catalyst into a polymerization reactor to form a polyolefin, the polymerization reactor including: a fluidized bed region having a top and a bottom; and a motive bed region; wherein a first end of the motive bed region is fluidly connected to the top of the fluidized bed region; and wherein a second end of the motive bed region is fluidly connected to the bottom of the fluidized bed region; and wherein a diameter of the fluidized bed region is greater than a diameter of the motive bed region; circulating at least a portion of the olefin, the catalyst, and the polyolefin through the fluidized bed region and the motive bed region; maintaining a dense-phase fluidized bed within the fluidized bed region; recovering polyolefin from the fluidized bed region, is provided. A reactor system directed to the process is also provided.
US08067508B2 Compositions consisting of partially silyl-terminated polymers
This disclosure relates to a curable composition comprising at least one polymer A with at least one reactive silyl group and at least one polymer B with at least one reactive silyl group, the number of reactive silyl groups in the polymer A being greater or equal to the number of silyl groups in polymer B and the reactive silyl groups being capable of cross-linking to form siloxane bonds. The disclosure also relates to preparations containing a composition of this type and to the use of said compositions.
US08067505B2 Method of preparing carboxylic acid functionalized polymers
Methods for preparing water soluble, non-peptidic polymers carrying carboxyl functional groups, particularly carboxylic acid functionalized poly(ethylene glycol) (PEG) polymers are disclosed, as are the products of these methods. In general, an ester reagent R(C═0)OR′, wherein R′ is a tertiary group and R comprises a functional group X, is reacted with a water soluble, non-peptidic polymer POLY-Y, where Y is a functional group which reacts with X to form a covalent bond, to form a tertiary ester of the polymer, which is then treated with a strong base in aqueous solution, to form a carboxylate salt of the polymer. Typically, this carboxylate salt is then treated with an inorganic acid in aqueous solution, to convert the carboxylate salt to a carboxylic acid, thereby forming a carboxylic acid functionalized polymer.
US08067500B2 Curable composition, bonding method and assembly
A curable composition and an adhesive which exhibit a temporarily fixing effect very quickly and which are completely cured quickly at room temperature, and a bonding method using such a composition. The curable composition including a component (A)], which is a polymerizable acrylic liquid composition, a component (B), which is cumene hydroperoxide, a component (C), which is a reducing agent containing vanadium or copper, or a reducing agent comprising ethylene thiourea, and a component (D), which is a basic compound having a primary, secondary, or tertiary amine structure.
US08067497B2 Flame-retardant for engineering thermoplastic applications
This invention provides a flame retardant for polymeric compositions which is a mixture consisting of high molecular weight brominated epoxides modified with tribromophenol, having a low content of organic solvents. The invention further relates to a method for the preparation of the retardant, and to its use in flame retarded engineering thermoplastics having good chemical, thermal, and mechanical properties.
US08067496B2 Curable silicone impression materials with high tear strength and low consistency
The invention relates to curable silicone compositions which contain silane based crosslinkers and a mixture of different organopolysiloxanes. The compositions are particularly suitable as curable impression materials in dental applications.
US08067494B2 Magnesium hydroxide-based flame retardant compositions made via in-situ hydration of polymer compounds comprising magnesium oxide
Magnesium oxide (MgO) compounded into a polymer can subsequently be hydrated in-situ within the polymer to form magnesium hydroxide. In the case of silane-based or peroxide-based crosslinkable resins, the MgO hydration and polymer crosslinking can be done in a single process step, or in sequential steps. In the case of non-crosslinkable compounds, hydration can be carried out after compounding (no crosslinking step). In all cases, steam CV, sauna, or hot water bath are options for hydration. This approach enables preparation of polymer compounds that are flame retarded with metal hydrates yet free of the traditional limitations posed by shelf instability, extrusion scorch, undesired dehydration, and processing temperature limitations posed by metal hydrates.
US08067489B2 Polymer blend nanocomposites using nanocompatibilizer and method of manufacture thereof
The invention for the nanocompatibilizer composed of a nanoclay and a compatibilizer prepared through a melt blending process is disclosed. The enhanced mechanical properties stemming from the increased compatibility for metallocene polyethylene/starch blends are attained with the addition of the nanocompatibilizer, in comparison with neat compatibilizer, which signified the role of nanocompatibilizer in the derived nanocomposites.
US08067488B2 Cellulose solutions comprising tetraalkylammonium alkylphosphate and products produced therefrom
This invention relates a cellulose solution comprising cellulose and at least one tetraalkylammonium alkylphosphate and processes to produce the cellulose solution. Another aspect of this invention relates to shaped articles prepared from a cellulose solution comprising cellulose and at least one tetraalkylammonium alkylphosphate. Another embodiment of this invention relates to compositions comprising derivatives of cellulose prepared from a cellulose solution comprising at least one tetraalkylammonium alkylphosphate. Another embodiment of this invention relates to compositions comprising regioselectively substituted cellulose esters prepared from a cellulose solution comprising cellulose and at least one tetraalkylammonium alkylphosphate. In another embodiment of the invention, the cellulose esters of the present invention are used as protective and compensation films for liquid crystalline displays.
US08067487B2 Method of making and use of a heavy duty pavement structure
The present invention is directed to a heavy duty pavement structure comprising an open-graded asphalt layer fortified with a non-segregating grout mixture. The heavy duty pavement structure is made through the steps including forming an open-graded asphalt layer and then fortifying the layer with a non-segregating grout mixture that includes a predetermined amount of portland cement, sand and cement binder system.
US08067478B1 Process for preparing polymer reinforced silica aerogels
Process for preparing polymer-reinforced silica aerogels which comprises a one-pot reaction of at least one alkoxy silane in the presence of effective amounts of a polymer precursor to obtain a silica reaction product, the reaction product is gelled and subsequently subjected to conditions that promotes polymerization of the precursor and then supercritically dried to obtain the polymer-reinforced monolithic silica aerogels.
US08067476B2 Foamed thermoplastic polyurethanes
Process for the preparation of foamed thermoplastic polyurethanes characterised in that the foaming of the thermoplastic polyurethane is carried out in the presence of thermally expandable microspheres.
US08067472B2 Methods of treating Hodgkin's and non-Hodgkin's lymphoma
The present invention provides methods of selectively inducing terminal differentiation, cell growth arrest and/or apoptosis of neoplastic cells, and/or inhibiting histone deacetylase (HDAC) by administration of pharmaceutical compositions comprising potent HDAC inhibitors. The oral bioavailability of the active compounds in the pharmaceutical compositions of the present invention is surprisingly high. Moreover, the pharmaceutical compositions unexpectedly give rise to high, therapeutically effective blood levels of the active compounds over an extended period of time. The present invention further provides a safe, daily dosing regimen of these pharmaceutical compositions, which is easy to follow, and which results in a therapeutically effective amount of the HDAC inhibitors in vivo.
US08067463B2 Protease inhibitor precursor synthesis
The present invention provides a compound having the structure (I) and processes for the production thereof and the intermediates used in such process.
US08067462B2 Processes of making sesquiterpenoid tashironin, its analogs and their uses
A compound having the structure of the formula (genus of compound 1 excluding Tashironin or Debenzoyltashironin) and methods of the same.
US08067461B2 3-acyl coumarins, thiochromones and quinolones and therapeutic uses thereof
Compounds of Formula I: wherein R1, R2, M, Q and n are as defined herein, are useful as antiproliferative agents including, for example, as anticancer agents.
US08067460B2 5-phenoxyalkoxypsoralens and methods for selective inhibition of the voltage gated Kv1.3 potassium channel
Compositions of matter comprising 5-phenoxyalkoxypsoralen compounds and their method of synthesis and use. The compounds are useable to treat diseases or disorders in human or animal subjects, including autoimmune diseases. The compounds inhibit potassium channels, including the Kv1.3 channel and at least some of the therapeutic effects of such compounds may be due at least in part to potassium channel inhibition. In some embodiments, the compounds are more selective for certain potassium channels (e.g., Kv1.3 channels) than other potassium channels (e.g., Kv1.5 channels).
US08067457B2 Compounds useful as antagonists of CCR2
The present invention provides compounds of general formula I: or a pharmaceutically acceptable salt thereof, wherein X, n, Y, and R1 are defined generally and in subsets herein. Compounds of the invention are inhibitors of CCR2 and accordingly are useful for the treatment of a variety of inflammatory, allergic, and autoimmune diseases, disorders, or conditions.
US08067456B2 Tetrahydrocarbazole derivatives having improved biological action and improved solubility as ligands of G-protein coupled receptors (GPCPs)
The present invention provides novel tetrahydrocarbazole derivatives which have improved properties and which can be employed as inhibitors of GPCRs. This results in the possibility of using the novel compounds to treat pathological conditions whose severity depends on the pathobiochemical effect of GPCRs. The compounds of the invention act in particular via an antagonistic inhibition of the LHRH receptor. The invention further provides medicaments which comprise one or more of the novel compounds as active ingredient. The medicaments are suitable in particular to be employed in an oral dosage form for a mammal, in particular a human.
US08067455B2 Amino acid derived prodrugs of propofol, compositions, uses and crystalline forms thereof
The present invention provides a prodrug of propofol and crystalline forms thereof, methods of making the propofol prodrug and crystalline forms thereof, pharmaceutical compositions of the propofol prodrug and crystalline forms thereof, methods of using the propofol prodrug and crystalline forms thereof and pharmaceutical compositions thereof to treat diseases or disorders such as headache pain, post-chemotherapy or post-operative surgery nausea and vomiting, neurodegenerative disorders, and mood disorders.
US08067454B2 Thio-substituted Anthra [1, 2-d] imidazole- 6, 11-dione derivatives, preparation method and application thereof
A series of novel thio-substituted anthra[1,2-d]imidazole-6,11-dione derivatives, and the preparation method and application of said derivatives, said application having a pharmaceutical composition containing said derivatives with therapeutically effective amount for treating cancer, and said application involves effects of said derivatives for inhibiting telomerase activity, inhibiting the growth of cancer cell, treating cancer and the like.
US08067445B2 N,N-disubstituted aminoalkylbiphenyl antagonists of prostaglandin D2 receptors
Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions and medicaments that include the compounds described herein that are antagonists of PGD2 receptors. Also described herein are methods of using such antagonists of PGD2 receptors, alone and in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.
US08067443B2 Arylvinylazacycloalkane compounds and methods of preparation and use thereof
Novel vinylazacycloalkane compounds of Formula (I) are disclosed. The compounds are ligands of various nAChRs. The compounds and their pharmaceutically acceptable salts can be used to prepare pharmaceutical compositions and/or medicaments intended to prevent or treat disorders associated with dysfunction of nAChRs, especially within the central nervous system or the gastrointestinal system. Examples of types of disorders that can be treated include neurodegenerative disorders, including central nervous system disorders such as Alzheimer's disease, cognitive disorders, motor disorders such as Parkinson's disease, drug addiction, behavioral disorders and inflammatory disorders within the gastrointestinal system. The compounds can also serve as analgesics in the treatment of acute, chronic or recurrent pain.
US08067442B2 Heterocyclic antiviral compounds
Compounds having the formula I wherein R1, R2a, R2b, R2c, R3, Y and p are as defined herein and C2-C3 is a single or double bond are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.
US08067440B2 Phosphonium salts derivatives and uses thereof
There are provided compounds of formulas (VA), (VIA), (VIIA) (IXA), (XIA), (XIIA), (XIIIA), and (XIVA): wherein A, Z, R2, X−, and L2 represent various different possibilities. Methods for using such compounds are also provided.
US08067438B2 Hepatitis C inhibitor compounds
Compounds of formula (I): wherein B, X, R3, L0, L1, L2, R2, R1 and RC are defined herein. The compounds are useful as inhibitors of HCV NS3 protease for the treatment of hepatitis C viral infection.
US08067432B2 Liposomal, ring-opened camptothecins with prolonged, site-specific delivery of active drug to solid tumors
A method for preparing a stable dispersion of a camptothecin, camptothecin prodrug, or analog thereof for administration to a patient in need thereof includes preparing a solution of the camptothecin, wherein the solution has a pH which places substantially an entirety of that camptothecin in a carboxylate form. The camptothecin may be a neutral camptothecin. The solution is next loaded into a liposome including at least one lipid, which may be a phospholipid. An intraliposomal pH is maintained which preserves substantially an entirety of the camptothecin in the carboxylate form. The liposomal dispersion is administered to an individual in need thereof, whereby the liposomes accumulate at and permeate into tumor tissue and an active, lactone form camptothecin is released in situ at the tumor site. Compositions formulated in accordance with the described method for treatment of a cancer in an animal in need thereof are provided also.
US08067431B2 Chemically modified small molecules
Methods of modifying the rate of systemic absorption of a drug administered to a subject by a pulmonary route, the method comprising covalently conjugating a hydrophilic polymer to a drug, wherein the drug has a half-life of elimination from the lung of less than about 180 minutes, to form a drug-polymer conjugate, wherein the drug-polymer conjugate has a net hydrophilic character and a weight average molecular weight of from about 50 to about 20,000 Daltons, and wherein the half-life of elimination from the lung of the drug-polymer conjugate is at least about 1.5-fold greater than the half-life of elimination from the lung of the drug, wherein the half-life of elimination from the lung is measured by bronchoalveolar lavage followed by assaying residual lung material.
US08067413B2 9-substituted-8-oxo-adenine compounds as toll-like receptor (TLR7 ) modulators
The present invention provides compounds of formula (I) wherein R1, Y1, X1, L and R2 are as defined in the specification, and pharmaceutically acceptable salts thereof, as well as processes for their preparation, pharmaceutical compositions containing them and their use in therapy.
US08067408B2 Dual pharmacophores—PDE4-muscarinic antagonistics
The present invention is directed to novel compounds of Formula (I), pharmaceutical compositions and their use in therapy, for example as inhibitors of phosphodiesterase type IV (PDE4) and as antagonists of muscarinic acetylcholine receptors (mAChRs), in the treatment of/and or prophylaxis of respiratory diseases, including antiinflammatory and/or allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma, rhinitis (e.g. allergic rhinitis), atopic dermatitis or psoriasis.
US08067407B2 Substituted dihydropyrazolones and their use
The present application relates to novel substituted dihydropyrazolone derivatives, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and haematological diseases and kidney diseases, and for promoting wound healing.
US08067404B2 Phthalocyanine derivatives, process for their preparation, pharmaceutical compositions containing them and their use
Phthalocyanine derivatives are described having photosensitizing characteristics and high solubility in water, useful for photodynamic treatment of bacterial infections, in particular infections generated by Gram-negative bacteria.
US08067399B2 Method and apparatus for transdermal or transmucosal application of testosterone
Methods, formulations, and devices for providing transdermal or transmucosal delivery of active agents to subjects in need thereof. The formulations and methods treat symptoms of hormonal disorders including hypogonadism, female sexual desire disorder, female menopausal disorder, and adrenal insufficiency.
US08067396B2 Amino alcohol compounds or phosphonic acid derivatives thereof
A compound having a formula II(a): wherein R1 and R2 are hydrogen lower alkyl, lower aliphatic acyl, or lower alkoxycarbonyl; R4 is C1-C4 alkyl; n is 2 or 3; X is a formula ═N-D, wherein D is hydrogen, C1-C6 alkyl or phenyl; Y is ethylene, ethynylene, —CO—CH2—, —CH(OH)—CH2— or phenylene; Z is C1-C6 alkylene; R5 is C3-C10 cycloalkyl or C6-C10 aryl; R6 and R7 are hydrogen, lower alkyl, halogeno lower alkyl, lower alkoxy or lower alkylthio; and R10 and R11 are hydrogen or lower alkyl.
US08067390B2 Therapeutic targeting of interleukins using siRNA in neutral liposomes
The present invention relates to the fields of molecular biology and drug delivery. In certain embodiments, the present invention provides compositions that include an siRNA targeted to an interleukin and a neutral lipid, and methods of treating a human subject with cancer involving administering to the subject a pharmaceutically effective amount of an interleukin-8 antagonist or a composition as set forth herein.
US08067389B2 Silencing of TGFβ type II receptor expression by siRNA
The present application is directed to siRNA-based silencing of the type II receptor of TGFβ. siRNAs that target this receptor abrogate the receptor protein and transcript, TGFβ-mediated processes such as fibronectin assembly and cell migration also are inhibited and the molecules of the invention are efficacious in reducing the inflammatory response and matrix deposition. These findings show that siRNAs can be successfully delivered both in vitro and in vivo to regulate the TGFβ type II receptor level and modulate wound response. Methods and compositions exploiting the findings of the present invention have a wide-ranging application, extending from treatment of disorders of the eye to other organs and tissues throughout the body.
US08067386B2 Modulation of eIF4E-BP2 expression
Compounds, compositions and methods are provided for modulating the expression of eIF4E-BP2. The compositions comprise oligonucleotides, targeted to nucleic acid encoding eIF4E-BP2. Methods of using these compounds for modulation of eIF4E-BP2 expression and for diagnosis and treatment of diseases and conditions associated with expression of eIF4E-BP2 are provided.
US08067385B2 Antiviral oligonucleotides targeting HBV
Random sequence oligonucleotides that have antiviral activity are described, along with their use as antiviral agents. In many cases, the oligonucleotides are greater than 40 nucleotides in length. Also described are methods for the prophylaxis or treatment of a viral infection in a human or animal, and a method for the prophylaxis treatment of cancer caused by oncoviruses in a human or animal. The methods typically involve administering to a human or animal in need of such treatment, a pharmacologically acceptable, therapeutically effective amount of at least oligonucleotide that does not act by a sequence complementary mode of action.
US08067380B2 Glutathione-based delivery system
A delivery system is provided. The delivery system includes a carrier or an active compound and a glutathione or a glutathione derivative grafted thereon. The invention also provides a compound including a moiety comprising a vitamin E derivative or a phospholipid derivative, a polyethylene glycol (PEG) or a polyethylene glycol derivative bonded thereto, and a glutathione (GSH) or a glutathione derivative bonded to the polyethylene glycol or the polyethylene glycol derivative.
US08067379B2 Sulfur compounds as inhibitors of hepatitis C virus NS3 serine protease
The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
US08067378B2 Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells
The embodiments include methods of treating conditions requiring removal or destruction of cellular elements, such as benign or malignant tumors in humans, using compounds based on small peptides. The method includes, but is not limited to, administering the compounds intramuscularly, orally, intravenously, intrathecally, intratumorally, intranasally, topically, transdermally, etc., either alone or conjugated to a carrier.
US08067375B2 Treatment of demyelinating disorders with soluble lymphotoxin-β-receptor
Methods of treating a demyelinating disorder using inhibitors of the lymphotoxin pathway.
US08067373B2 Therapeutic fibrin-derived peptides and uses thereof
The invention relates to peptides having the general formula (I), or a salt or amide thereof, wherein R1 and R2 are either the same or different, wherein R1 and R2 are each selected from the group consisting of hydrogen and a saturated or unsaturated hydrocarbon residue, said residue having from 1 to 10 carbon atoms, wherein Z1 is selected from the group consisting of histidine and proline, wherein Z2 is selected from the group consisting of an arginine and a peptide comprising an initial arginine and having from 2 to 30 amino acids. The invention also relates to methods using the peptides of the present invention in the treatment of inflammation.
US08067370B2 Pain-sensitive therapeutic wound dressing
Disclosed is a wound dressing comprising a therapeutic agent and a matrix comprising polymers joined by cross-linkages, wherein the cross-linkages comprise oligopeptidic sequences which are cleavable by a kallikrein associated with wound fluid such that the rate of release of the therapeutic agent increases in the presence of elevated kallikrein levels.
US08067369B2 Protection of the retina against laser injury by NAP and related peptides
This invention relates to the use of ADNF polypeptides in the treatment of laser-induced retinal damage and related conditions.
US08067367B2 Methods of increasing platelet and hematopoietic stem cell production
A method of increasing hematopoietic stem cell production is disclosed. The method includes administering a TPO mimetic compound to a subject. Pharmaceutical compositions including a TPO mimetic compound and a pharmaceutically acceptable carrier are also disclosed.
US08067364B2 Deer antler extract for promoting angiogenesis
An isolated extract of deer velvet which contains components which have molecular weights that are substantially are less than or equal to 10 kDa and which have a proliferative effect on endothelial cells and/or promote angiogenesis.
US08067362B2 Insulin derivatives
The present invention relates to insulin derivatives having a side chain attached either to the -amino group of the N-terminal amino acid residue of the B chain or to the amino group of a Lys residue present in the B chain of the parent insulin via an amide bond which side chain comprises at least one aromatic group; at least one free carboxylic acid group or a group which is negatively charged at neutral pH, a fatty acid moiety with 4 to 22 carbon atoms in the carbon chain; and possible linkers which link the individual components in the side chain together via amide bonds.
US08067357B2 Annexin derivatives suitable for pretargeting in therapy and diagnosis
The present invention provides methods and compositions for the treatment and diagnosis of diseases such as neoplastic diseases, neurodegenerative diseases, cardiovascular diseases, autoimmune diseases, and inflammatory diseases. The methods are based on the concept of pretargeting and include the administration of complexes comprising a recognizable compound A coupled to annexins, and the administration of complexes comprising of pharmaceutical or diagnostic compounds coupled to a compound B recognizing and binding to compound A to subjects. The compositions include annexins, annexin variants, that are not internalized by the target cells, derivatives thereof, and complexes thereof.
US08067356B2 High fibre high calorie liquid or powdered nutritional composition
The present invention relates to a nutritional composition which is liquid and shelf-stable or powdered and reconstitutable. The composition has a fiber content of more than 2.5 g/fibber per 100 ml of the composition. Furthermore, it has an energy content of 1.3-1.8 kcal/ml. The composition is useful to improve and maintain gut comfort, restoring a well-balanced gut flora, especially in an elderly patient prone to malnutrition. The invention further relates to a process for preparing the nutritional composition.
US08067352B2 Aqueous cleaning composition for semiconductor copper processing
The invention relates to an aqueous cleaning composition for use in a cleaning process during or after a chemical mechanical planarization for a copper integrated circuit processing, comprising 0.05 to 20 wt % of a nitrogen-containing heterocyclic organic base, 0.05 to 50 wt % of an alcohol amine, 0.01-10 wt % of a quaternary ammonium hydroxide, and water. When used during or after the planarization process, the inventive cleaning composition of the invention can effectively remove residual contaminants from the surfaces of the wafers and simultaneously maintain a good surface roughness of the wafers.
US08067350B2 Color changing cleansing composition
A cleansing composition is disclosed that changes color during use. The cleansing composition contains a plurality of thermochromic dyes that cause a color change to occur at a threshold temperature and continue to cause a color change over a temperature range. The range of temperatures corresponds to approximately the amount of time sufficient to properly wash or scrub using the product.
US08067348B2 Marine engine lubrication
A trunk piston marine engine lubricating oil composition for a medium-speed compression-ignited marine engine comprises, in a major amount, an oil of lubricating viscosity containing 50 mass % or more of a Group II basestock, and, in respective minor amounts, (A) an overbased metal hydrocarbyl-substituted hydroxybenzoate detergent having a basicity index of 5.5 or greater, and (B) an overbased metal hydrocarbyl-substituted hydroxybenzoate detergent having a basicity index in the range of 2.1 to 5.4. The ratio of the mass of metal in detergent (A) to the mass of metal in detergent (B) is 1 or less. The trunk piston marine engine lubricating oil composition has a TBN (using ASTM D2896) of 20 to 60.
US08067345B2 Refrigerator oil composition
A refrigerator oil composition includes: a synthetic base oil; and a partial hydrocarbyl ether of an aliphatic polyhydric alcohol condensate, in which the aliphatic polyhydric alcohol condensate includes a condensate of 4 to 20 molecules of a hindered glycol and/or an aliphatic polyhydric alcohol having 3 to 6 hydroxyl groups. The refrigerator oil composition is preferably used in a compression refrigerator that uses a hydrofluorocarbon, a natural refrigerant such as a hydrocarbon, carbon dioxide, or ammonia, a mixed refrigerant of fluoroiodomethane and propene, an unsaturated fluorinated hydrocarbon, a fluorinated ether, a fluorinated alcohol, a fluorinated ketone, or a mixture thereof as a refrigerant, has a low coefficient of friction, and is excellent in energy-saving property.
US08067340B2 Methods for discretized processing and process sequence integration of regions of a substrate
The present invention provides methods and systems for discretized, combinatorial processing of regions of a substrate such as for the discovery, implementation, optimization, and qualification of new materials, processes, and process sequence integration schemes used in integrated circuit fabrication. A substrate having an array of differentially processed regions thereon is processed by delivering materials to or modifying regions of the substrate.
US08067339B2 Surface display of whole antibodies in eukaryotes
Methods for display of recombinant whole immunoglobulins or immunoglobulin libraries on the surface of eukaryote host cells, including yeast and filamentous fungi, are described. The methods are useful for screening libraries of recombinant immunoglobulins in eukaryote host cells to identify immunoglobulins that are specific for an antigen of interest.
US08067338B2 Trichloro silyl alkyl isocyanate molecule and surface modified mineral substrate
A compound having formula (I): X—E—Si−Cl3  (I) wherein:X represents an isocyanate function;E represents a straight, branched or cyclic alkyl chain comprising from 4 to 30 carbon atoms, and optionally contains a bridge function of —O—, —S—, —NH— or aryl;and X and SiCl3 are separated by a chain of at least 4 carbon atoms.
US08067336B2 Cardboard cylinder for a heat-sensitive transfer image-receiving sheet, rolled heat-sensitive transfer image-receiving sheet to form a roll shape, and image-forming method
A cardboard cylinder for winding a heat-sensitive transfer image-receiving sheet having a receptive layer on one surface of a support around the cardboard cylinder, wherein an innermost surface of the cardboard cylinder is composed of a layer containing a polyolefin resin having a number average molecular weight of 12,000 or more in a proportion of at least 80% by mass based on the layer.
US08067333B2 Catalysts
A process for producing a supported cobalt-based Fischer-Tropsch synthesis catalyst includes, in a first activation stage, treating a particulate catalyst precursor with a reducing gas, at a heating rate, HR1, until the precursor has reached a temperature, T1, where 80° C.≦T1≦180° C., to obtain a partially treated precursor. In a second activation stage, the partially treated precursor is treated with a reducing gas, at an average heating rate, HR2, with x step increments, where 0HR2 until the partially reduced precursor reaches a temperature, T2. The partially reduced precursor is maintained at T2 for a time, t2, where t2 is from 0 to 20 hours, to obtain an activated catalyst.
US08067332B2 Methanation catalyst, and carbon monoxide removing system, fuel processor, and fuel cell including the same
A methanation catalyst, a carbon monoxide removing system, a fuel processor, and a fuel cell including the same, and more particularly a non-supported methanation catalyst including the catalytically active non-precious metal particles and the metal oxide particles, and a carbon monoxide removing system, a fuel processor, and a fuel cell including the same. The methanation catalyst has high selectivity for the methanation of carbon monoxide instead of the methanation of carbon dioxide and the reverse water gas shift reaction of carbon dioxide, which are side reactions of the methanation of carbon monoxide, maintains high concentration of generated hydrogen as small amounts of hydrogen and carbon dioxide are consumed, and effectively removes carbon monoxide at low operating temperatures of 200° C. or less.
US08067331B2 Bulk catalyst comprising nickel tungsten metal oxidic particles
The invention relates to a nickel tungsten bulk catalyst, to a process for the manufacture of said catalyst and to the use of said catalyst for the hydrotreatment, in particular the hydrodesulphurisation and hydrodenitrogenation of hydrocarbon feedstock. The catalyst comprises nickel tungsten metal oxidic particles obtainable by a process comprising forming a slurry of a first solid metal compound comprising Group VNI metal nickel and a second solid metal compound comprising Group VIB metal tungsten in a protic liquid, reacting the first and second solid metal compounds at elevated temperature whereby the first and second solid metal compounds remain at least partly in the solid state during the entire reaction to form the nickel tungsten oxidic bulk catalyst.
US08067329B2 Boron-based catalysts
Boron based catalysts and processes for preparing the catalysts are provided. The catalysts are suitable for the alkoxylation of alcohols using alkylene epoxides.
US08067328B2 Polymerisation and oligomerisation catalysts
A polymerization catalyst composition comprising (1) a transition metal compound of Formula (A), Z being 5-membered heterocyclic containing at least one carbon, at least one nitrogen and at least one of nitrogen, sulphur and oxygen, the others being nitrogen or carbon; M is a Group 3 to 11 metal or a lanthamide metal; E1 and E2 are divalent groups of aliphatic, alicyclic, aromatic or alkyl substituted aromatic hydrocarbon, or heterocyclic; D1 and D2 are donor atoms or groups; X is an anionic group, L is a neutral donor group; n=m=zero or 1; y and z are zero or integer such that X and L satisfy valency/oxidation state of M, (2) a catalyst-activating support which is a solid particulate substance, insoluble in hydrocarbons, comprising at least magnesium and aluminum atoms and hydrocarbyloxy groups containing 1 to 20 carbon atoms, the molar ration of Mg/Al being in the range 1.0 to 300 and the molar ratio of hydrocarbyloxy groups to aluminum atoms being in the range 0.5 to 2.0, and optionally, (3) an additional activator selected from aluminum alkyl and boron compounds.
US08067325B2 Semiconductor ceramic composition
It is intended to provide a semiconductor ceramic composition containing no Pb, which is capable of shifting the Curie temperate to a positive direction as well as of controlling room temperature resistivity and having an excellent jump characteristic. Since the semiconductor ceramic composition in which a portion of Ba of BaTiO3 is substituted by Bi—Na has a crystal in which a central part and an outer shell part of a crystal grain are different from each other in composition, the composition is capable of improving control of room temperature resistivity and a jump characteristic, and therefore it is optimum as a material for a PTC thermistor, a PTC heater, a PTC switch, a temperature detector, and the like.
US08067324B2 Low dielectric loss ceramic ferroelectric composite material
The ceramic ferroelectric composite material ensures the achievement of the technical result, consisting in a decrease in the level of the dielectric losses in the radio and microwave frequencies for the materials with the dielectric constant from 152 to 796 together with an increase in the tunability of the dielectric constant by the electric field. The ceramic ferroelectric composite material is produced from the composition including BaTiO3 and SrTiO3, which additionally includes the magnesium-containing mixture of magnesium orthotitanate Mg2TiO4 and magnesia MgO, with the following content of components, mass%: BaTiO3 - 27.0 - 48.8; SrTiO3 - 25.0 - 39.5; magnesium-containing mixture of Mg2TiO4 and MgO - the remainder, where the components in the magnesium-containing mixture have the following content, mass%: Mg2TiO4 - 6.2 - 92.4: MgO - the remainder.
US08067320B2 Spunbonded nonwoven fabric
There is provided by the present invention a spunbonded nonwoven fabric which is formed from fibers comprising a propylene-based polymer and has MFR of 65 to 150 g/10 min and a fineness of 0.01 to 1.5 deniers, wherein the basis weight is in the range of 5 to 40 g/m2 and the embossed area ratio is in the range of 6.5 to 25%.
US08067317B2 Stab resistant and anti-ballistic material and method of making the same
The invention relates to a fabric having both stab resistant and anti-ballistic properties. The fabric is made of yarn of a weight greater than about 500 dtex, and the fabric has a minimum shrinkage factor of at least about 1% achieved through a densification treatment. The invention further relates to a method of producing a such a fabric having the steps of agitating a fabric made of a yarn of a weight greater than about 500 dtex, substantially removing a spin finish from the fabric before, during or after the agitating step, and drying the fabric.
US08067315B2 Microstructure device including a compressively stressed low-k material layer
A nitrogen-containing silicon carbide material may be deposited on the basis of a single frequency or mixed frequency deposition recipe with a high internal compressive stress level up to 1.6 GPa or higher. Thus, this dielectric material may be advantageously used in the contact level of sophisticated integrated circuits, thereby providing high strain levels while not unduly contributing to signal propagation delay.
US08067311B2 Mask and method for fabricating semiconductor device using the same
A mask for forming a metal line and a via contact, and a method for fabricating a semiconductor device using the same, minimizes misalignment. The mask includes a first mask region having a dark tone for light shading, a second mask region having a half tone, being disposed within the first mask region to form the metal line, and a third mask region having a clear tone, being disposed within the second mask region to form the via contact.
US08067308B2 Semiconductor device and method of forming an interconnect structure with TSV using encapsulant for structural support
A semiconductor device has a conductive via formed through in a first side of the substrate. A first interconnect structure is formed over the first side of the substrate. A semiconductor die or component is mounted to the first interconnect structure. An encapsulant is deposited over the first interconnect structure and semiconductor die or component. A portion of a second side of the substrate is removed to reduce its thickness and expose the TSV. A second interconnect structure is formed over the second side of the substrate. The encapsulant provides structural support while removing the portion of the second side of the substrate. The second interconnect structure is electrically connected to the conductive via. The second interconnect structure can include a redistribution layer to extend the conductivity of the conductive via. The semiconductor device is mounted to a printed circuit board through the second interconnect structure.
US08067304B2 Method for forming a patterned thick metallization atop a power semiconductor chip
A method is disclosed for forming a patterned thick metallization atop a semiconductor chip wafer. The method includes fabricating a nearly complete semiconductor chip wafer ready for metallization; depositing a bottom metal layer of sub-thickness TK1 together with its built-in alignment mark using a hot metal process; depositing a top metal layer of sub-thickness TK2 using a cold metal process thus forming a stacked thick metallization of total thickness TK=TK1+TK2; then, use the built-in alignment mark as reference, patterning the stacked thick metallization. A patterned thick metallization is thus formed with the advantages of better metal step coverage owing to the superior step coverage nature of the hot metal process as compared to the cold metal process; and lower alignment error rate owing to the lower alignment signal noise nature of the cold metal process as compared to the hot metal process.
US08067302B2 Defect-free junction formation using laser melt annealing of octadecaborane self-amorphizing implants
A method and apparatus for implanting a semiconductor substrate with boron clusters. A substrate is implanted with octadecaborane by plasma immersion or ion beam implantation. The substrate surface is then melted, resolidified, and annealed to completely dissociate and activate the boron clusters.
US08067299B2 Nanoelectronic structure and method of producing such
The present invention relates to semiconductor devices comprising semiconductor nanoelements. In particular the invention relates to devices having a volume element having a larger diameter than the nanoelement arranged in epitaxial connection to the nanoelement. The volume element is being doped in order to provide a high charge carrier injection into the nanoelement and a low access resistance in an electrical connection. The nanoelement may be upstanding from a semiconductor substrate. A concentric layer of low resistivity material forms on the volume element forms a contact.
US08067297B2 Process for deposition of semiconductor films
Chemical vapor deposition processes utilize higher order silanes and germanium precursors as chemical precursors. The processes have high deposition rates yet produce more uniform films, both compositionally and in thickness, than films prepared using conventional chemical precursors. In preferred embodiments, trisilane is employed to deposit SiGe-containing films that are useful in the semiconductor industry in various applications such as transistor gate electrodes.
US08067293B2 Power semiconductor device and method of manufacturing the same
A semiconductor device and a method of manufacturing the same. The method includes preparing a semiconductor substrate having high-voltage and low-voltage device regions, forming a field insulating layer in the high-voltage device region, forming a first gate oxide layer on the semiconductor substrate, exposing the semiconductor substrate in the low-voltage device region by etching part of the first gate oxide layer and also etching part of the field insulating layer to form a stepped field insulating layer, forming a second gate oxide layer on the first gate oxide layer in the high-voltage device region and on the exposed semiconductor substrate in the low-voltage device region, and forming a gate over the stepped field insulating layer and part of the second gate oxide layer in the high-voltage device region adjoining the field insulating layer.
US08067292B2 Isolation structure, non-volatile memory having the same, and method of fabricating the same
A method of forming an isolation structure, comprising: (a) providing a base having a recess; (b) forming a stop layer on the base and in the recess; (c) forming a dielectric material on the stop layer so as to allow the rest of the recess to be filled with the dielectric material; (d) removing the dielectric material over the base by performing a chemical mechanical polishing (CMP) process until a part of the stop layer is exposed so as to form a dielectric layer in the recess; and (e) removing a part of the stop layer, wherein the another part of the stop layer and the dielectric layer filled in the recess constitute the isolation structure.
US08067285B2 Methods of forming a conductive layer structure and methods of manufacturing a recessed channel transistor including the same
In a method of forming a conductive layer structure and a method of manufacturing a recess channel transistor, a first insulating layer and a first conductive layer are sequentially formed on a substrate having a first region a second region and the substrate is exposed in a recess-forming area in the first region. A recess is formed in the recess-forming-area by etching the exposed region of the substrate. A second insulating layer is conformally formed on a sidewall and a bottom of the recess. A second conductive layer pattern is formed on the second insulating layer to fill up a portion of the recess. A spacer is formed on the second conductive layer pattern and on the second insulating layer on the sidewall of the recess. A third conductive layer pattern is formed on the second conductive layer pattern and the spacer to fill up the recess.
US08067282B2 Method for selective formation of trench
A method for selective formation of trenches is disclosed. First, a substrate is provided. The substrate includes a first semiconductor element and a second semiconductor element. The first semiconductor element has a dopant. Second, a wet etching procedure is carried out to selectively form a pair of trenches in the substrate around the second semiconductor element, a first source/drain ion implantation is selectively carried out on the first semiconductor element, or a second source/drain ion implantation is selectively carried out on the second semiconductor element.
US08067279B2 Application of different isolation schemes for logic and embedded memory
The present invention facilitates semiconductor device fabrication by providing mechanisms for utilizing different isolation schemes within embedded memory and other logic portions of a device. The isolation mechanism of the embedded memory portion is improved relative to other portions of the device by increasing dopant concentrations or reducing the depth of the dopant profiles within well regions of the embedded memory array. As a result, smaller isolation spacing can be employed thereby permitting a more compact array. The isolation mechanism of the logic portion is relatively less than that of the embedded memory portion, which permits greater operational speed for the logic.
US08067278B2 Semiconductor device and method for manufacturing the same
A semiconductor device includes at least one thin film transistor including a semiconductor layer that has a crystalline region including a channel region, a source region and a drain region, a gate insulating film disposed at least on the channel region, the source region and the drain region of the semiconductor layer, and a gate electrode arranged so as to oppose the channel region via the gate insulating film. At least a portion of the semiconductor layer includes a catalyst element capable of promoting crystallization, and the semiconductor layer further includes a gettering region that includes the catalyst element at a higher concentration than in the channel region or the source region and the drain region. The thickness of the gate insulating film on the gettering region is smaller than that on the source region and the drain region, or the gate insulating film is not disposed on the gettering region.
US08067277B2 Active matrix device with photo sensor
An active matrix pixel device is provided, for example an electroluminescent display device, the device comprising circuitry supported by a substrate and including a polysilicon TFT (10) and an amorphous silicon thin film PIN diode (12). Polysilicon islands are formed before an amorphous silicon layer is deposited for the PIN diode. This avoids the exposure of the amorphous silicon to high temperature processing. The TFT comprises doped source/drain regions (16a,17a), one of which (17a) may also provide the n-type or p-type doped region for the diode. Advantageously, the requirement to provide a separate doped region for the photodiode is removed, thereby saving processing costs. A second TFT (10b) having a doped source/drain region (16b,17b) of the opposite conductivity type may provide the other doped region (16b) for the diode, wherein the intrinsic region (25) is disposed laterally between the two TFTs, overlying each of the respective polysilicon islands.
US08067274B2 Method of forming wiring on a plurality of semiconductor devices from a single metal plate, and a semiconductor construction assembly formed by the method
In this manufacturing method of a semiconductor device, a metal plate having a plurality of projection electrodes in each of a plurality of semiconductor device formation areas is prepared. Next, the projection electrodes of each of the semiconductor formation areas are aligned corresponding to external connection electrodes of each semiconductor construction, and each semiconductor construction is separately arranged on the projection electrodes in the semiconductor device formation areas. Next, an insulating layer formation sheet is arranged on the metal plate, and the metal plate and the insulating layer formation sheet are joined by heat pressing. Then, the metal plate is patterned and a plurality of upper layer wirings that connect to the projection electrodes is formed.
US08067268B2 Stacked integrated circuit package system and method for manufacturing thereof
A method for manufacturing of a stacked integrated circuit package system includes: providing a base integrated circuit package having a base encapsulation with a cavity therein and a base interposer exposed by the cavity; mounting an intermediate integrated circuit package over the base interposer; and mounting a top integrated circuit package over the intermediate integrated circuit package.
US08067264B2 Polythiophenes and devices thereof
An electronic device containing a polythiophene wherein R represents a side chain, m represents the number of R substituents; A is a divalent linkage; x, y and z represent, respectively, the number of Rm substituted thienylenes, unsubstituted thienylenes, and divalent linkages A, respectively, in the monomer segment subject to z being 0 or 1, and n represents the number of repeating monomer segments in the polymer or the degree of polymerization.
US08067260B1 Fabricating sub-lithographic contacts
A small critical dimension element, such as a heater for an ovonic unified memory, may be formed within a pore by using successive sidewall spacers. The use of at least two successive spacers enables the limitations imposed by lithography and the limitations imposed by bread loafing be overcome to provide reduced critical dimension elements.
US08067255B2 Nitride semiconductor light emitting device, method of manufacturing nitride semiconductor light emitting device, and nitride semiconductor transistor device
Provided are a nitride semiconductor light emitting device including a coat film formed at a light emitting portion and including an aluminum nitride crystal or an aluminum oxynitride crystal, and a method of manufacturing the nitride semiconductor light emitting device. Also provided is a nitride semiconductor transistor device including a nitride semiconductor layer and a gate insulating film which is in contact with the nitride semiconductor layer and includes an aluminium nitride crystal or an aluminum oxynitride crystal.
US08067254B2 Common optical element for an array of phosphor converted light emitting devices
A device is provided with an array of a plurality of phosphor converted light emitting devices (LEDs) that produce broad spectrum light. The phosphor converted LEDs may produce light with different correlated color temperature (CCT) and are covered with an optical element that assists in mixing the light from the LEDs to produce a desired correlated color temperature. The optical element may be bonded to the phosphor converted light emitting devices. The optical element may be a dome mounted over the phosphor converted light emitting devices and filled with an encapsulant.
US08067253B2 Electrical device and method of manufacturing electrical devices using film embossing techniques to embed integrated circuits into film
An electrical device and method of making same is provided wherein a chip or other electrical component is embedded in a substrate. The substrate may be a thermoplastic material capable of deforming around the chip and at least partially encasing the chip when heat and/or pressure is applied to the substrate. Electromagnetic radiation such a near infrared radiation can be used to heat the substrate. The substrate may include a compressible layer that can be compressed and/or crushed to form a recess into which the chip can be inserted. Once embedded, the chip or electrical component is secured by the substrate and may be coupled to another electrical component. A method of making an RFID transponder is also provided wherein an RFID chip is embedded in a substrate using heat and/or pressure, an antenna structure is applied to the substrate, and the RFID chip and antenna structure are coupled together.
US08067252B2 Method for determining low-noise power spectral density for characterizing line edge roughness in semiconductor wafer processing
According to one exemplary embodiment, a method for determining a power spectral density of an edge of at least one patterned feature situated over a semiconductor wafer includes measuring the edge of the at least one patterned feature at a number of points on the edge. The method further includes determining an autoregressive estimation of the edge of the at least one patterned feature using measured data corresponding to a number of points on the edge. The method further includes determining a power spectral density of the edge using autoregressive coefficients from the autoregressive estimation. The method further includes utilizing the power spectral density to characterize line edge roughness of the at least one patterned feature in a frequency domain.
US08067237B2 Scaffolds for cell transplantation
A device that includes a scaffold composition and a bioactive composition with the bioactive composition being incorporated into or coated onto the scaffold composition such that the scaffold composition and/or a bioactive composition controls egress of a resident cell or progeny thereof. The devices mediate active recruitment, modification, and release of host cells from the material.
US08067234B2 Adipose stromal stem cells for tissue and vascular modification
Methods are provided for isolating adipose derived stromal cells from an animal by extracting adipose tissue from the patient, dissecting the tissue, dissociating the tissue into a cell suspension, removing the adipocytes, exposing the cell suspension to red cell lysis buffer, and isolating adipose derived stromal cells.
US08067230B2 Prostatic stem cells, isolation and uses
Prostatic stem cells have been isolated. Benign prostatic hyperplasia and other proliferative diseases of the prostate may arise in prostatic stem cells. The prostatic stem cells are used as a research tool for studying cancer and other proliferative diseases of the prostate, and for developing diagnostics and therapeutics for proliferative diseases of the prostate. Antibodies to the antigens expressed by prostatic stem cells can be used as therapeutics or diagnostics or can be used to deliver therapeutic or diagnostic agents directly to the prostatic stem cells.
US08067217B2 Method for preserving reduced coenzyme Q10
The present invention has its object to provide a method for stably preserving a capsule containing reduced coenzyme Q10, which is useful as foods, functional nutritive foods, specific health foods, nutritional supplements, nutrients, animal drugs, drinks, feeds, cosmetics, medicines, remedies, preventive drugs, etc. The present invention relates to a method for preserving reduced coenzyme Q10 which comprises producing or obtaining a capsule containing reduced coenzyme Q10, and controlling environment surrounding the capsule to a relative humidity of not less than 0% but not more than 60%. According to this method, reduced coenzyme Q10 can be preserved stably, without requiring huge cost and labor, or special equipment.
US08067212B2 Bacillus pumilus strain for high yield of tetramethylpyrazine
This invention provides a high-yield bacterial strain for producing tetramethylpyrazine named Bacillus pumilus RX3-17. The strain has been deposited in China Center for Type Culture Collection on Apr. 19, 2006. The deposit number is CCTCC M 206043. The bacterial strain, isolated from soil, is rod-shaped, 1.5 μm to 3.0 μm in length and 0.6 μm to 0.7 μm in diameter. The colony color of the strain is milky-white. The strain has typical physiological and biochemical characteristics of Bacillus pumilus. The 16s rDNA sequence of this strain shares a similarity of 99% with other Bacillus pumilus strains. This invention belongs to the domain of biotechnology. The strain can be applied to the production of tetramethylpyrazine with glucose as the substrate, solving the bottleneck of low yield in bacterial tetramethylpyrazine fermentation.
US08067211B2 Method for production of L-glutamine
A polypeptide comprising an amino acid sequence in which one or more amino acids are deleted, substituted or added in the amino acid sequence of a glutamine synthetase 2 derived from a microorganism belonging to a coryneform bacterium, wherein the coryneform bacterium producing the polypeptide has L-glutamine productivity, a DNA encoding the polypeptide, a recombinant DNA comprising the DNA, a microorganism comprising the DNA or the recombinant DNA, and a process for producing L-glutamine using the microorganism are provided.
US08067209B2 Method of screening for the presence of a genetic defect associated with deep venous thrombosis
The present invention relates to a method for screening an individual for the presence in his/her genome of a genetic marker that is indicative of an increased risk of deep venous thrombosis, wherein the genetic marker is haplotype 2 of the fibrinogen γ gene (FGG-H2) as given in FIG. 5A. The genetic marker comprises a set of one, two, three or four mutations in the nucleic acid material encoding fibrinogen γ, the mutations being selected from the group consisting of 129A/T (rs2066854), 7874G/A (rs20668β1), 9615′C/T (rs2066864) and 10034C/T (rs2066865).
US08067208B2 Probes and methods for hepatitis C virus typing using multidimensional probe analysis
This invention provides compositions and methods for HCV typing, e.g., genotyping and/or subtyping. The compositions and methods of the invention can be used to assign an HCV isolate to one of at least five HCV types (for example, selected from types 1, 2, 3, 4, 5 or 6), or to one of at least five subtypes (for example, subtypes 1a/b/c, 2a/c, 2b, 3a, 4a, 5a or 6a). These methods integrate the hybridization data from a plurality of HCV typing probes in a multidimensional analysis to make an HCV type assignment for an HCV in an experimental sample. The invention also provides related compositions, including, for example, the HCV typing probes and HCV typing diagnostic kits.
US08067207B2 Species-specific, genus-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial and fungal pathogens and associated antibiotic resistance genes from clinical specimens for diagnosis in microbiology laboratories
Embodiments disclosed herein relate to methods and compositions for species-specific detection of bacterial and fungal nucleic acids and nucleic acids of antibiotic resistance genes.
US08067202B2 Bacterial superantigen vaccines
The present invention relates to genetically attenuated superantigen toxin vaccines altered such that superantigen attributes are absent, however the superantigen is effectively recognized and an appropriate immune response is produced. The attenuated superantigen toxins are shown to protect animals against challenge with wild type toxin. Methods of producing and using the altered superantigen toxins are described.
US08067197B2 Soluble recombinant αvβ3 adhesion receptor
The invention relates to a novel purified recombinant αVβ3 adhesion receptor which shows an unimpaired ligand binding activity, and a process for preparing said soluble non-membrane bound receptor in excellent yields by recombinant techniques using a baculovirus-insect cell expression system. The so-synthesized soluble receptor may be used very easily as screening tool for new therapeutic compounds which may inhibit the natural αVβ3 adhesion receptor. Such therapeutic compounds which can be discovered very easily, fast and without health risk by means of the soluble receptors according to the invention may be, for example, RGD peptides or non-peptidic compounds mimicking the natural ligand epitopes. The invention relates, furthermore, to a corresponding process for preparing recombinant full-length αVβ3 adhesion receptor in excellent yields, additionally using detergents to dissolve the membrane bound receptor from the surface of the host cell.
US08067196B2 6-O sulfated polysaccharides and methods of preparation thereof
Disclosed are methods of 6-O-sulfating glucosaminyl N-acetylglucosamine residues (GlcNAc) in a polysaccharide preparation and methods of converting anticoagulant-inactive heparan sulfate to anticoagulant-active heparan sulfate and substantially pure polysaccharide preparations may by such methods. Also disclosed is a mutant CHO cell which hyper-produces anticoagulant-active heparan sulfate. Methods for elucidating the sequence of activity of enzymes in a biosynthetic pathway are provided.
US08067193B2 Production of a fermentation product
A process of separating suspended solids from a fermentation liquor by subjecting the liquor to a solids-liquid separation stage, wherein the fermentation liquor is produced in a fermentation process for the production of a fermentation product, in which the liquor has been subjected to a temperature of at least 50° C., wherein the solids-liquid separation stage is assisted by a treatment system, characterised in that the treatment system comprises an anionic polymer selected from natural polymers and modified natural polymers having a high anionic charge such that the equivalent weight is below 300, and synthetic polymers formed from at least 50% by weight anionic monomer units.
US08067189B2 Methods for determining sensitivity to vascular endothelial growth factor receptor-2 modulators by measuring the level of collagen type IV
VEGFR-2 biomarkers useful in a method for identifying and monitoring a mammal that will respond therapeutically to a method of treating cancer comprising administering an VEGFR-2 modulator, wherein the method comprises (a) exposing the mammal to the VEGFR-2 modulator and (b) measuring in the mammal the level of the at least one biomarker, wherein a difference in the level of the at least one biomarker measured in (b) compared to the level of the biomarker in a mammal that has not been exposed to the VEGFR-2 modulator indicates that the mammal will respond therapeutically to the method of treating cancer and (c) wherein the level of the biomarker in a mammal after exposure to a VEGFR-2 modulator indicates that the mammal has responded therapeutically to the method of treating cancer.
US08067184B2 Optoelectronic detection system
The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the invention provides methods of detecting a nucleic acid sequence in a sample. Also described is an emittor cell comprising an Fc receptor and an emittor molecule for the detection of a target particle in a sample wherein the target particle to be detected is bound by one or more antibodies. Also provided is an optoelectronic sensor device for detecting a target particle in a plurality of samples.
US08067182B2 Method of weak partitioning chromatography
This invention relates to methods of using weak partitioning chromatography for the purification of a product from a load fluid containing one or more impurities. Further, the invention relates to methods of weak partitioning chromatography defined by operating conditions which cause a medium to bind least 1 mg of product per mL of medium, or alternatively, defined by a partition coefficient of at least 0.1.
US08067176B2 Microchemistry reaction method
A chemical reaction is conducted in a fluid of a droplet inside a reaction receptacle or on a surface of a reaction substrate. Fluctuations of a magnetic field are applied to the droplet including an aqueous solution having magnetic body particles with a hydrophilic surface, and a physical force is transmitted to the surrounding aqueous solution through the magnetic body particles. The droplet is thus moved by the physical force to conduct an operation necessary for a chemical reaction.
US08067175B2 Methods and compositions for detecting a drug resistant EGFR mutant
Polymerase chain reaction primers and methods directed to detecting the EGFR mutant C→T at the position corresponding to base 2369 of EGFR cDNA. The invention provides a PCR primer that hybridizes under suitable PCR conditions to a polynucleotide sequence 5′ in each respective strand to a mutation of an EGFR gene that encodes a substitution of threonine by methionine at position 790 of the EGFR polypeptide. The invention also provides a PCR primer hybridizes to a sequence that includes a mutant T at the position corresponding to base 2369 of EGFR cDNA but not to a second EGFR polynucleotide containing a wild type C. The invention provides several methods and kits for detecting a mutant epidermal growth factor receptor (EGFR) gene in a sample comprising probing the sample with a means for selectively detecting a nucleotide sequence comprising a mutant T at the position corresponding to base 2369 of EGFR cDNA, and identifying that the base at said position is T. These methods and kits are also useful to predict resistance to the therapeutic effects of gefitinib or erlotinib in a subject suffering from or suspected of having a cancer.
US08067171B2 Methods and compositions for improved fertilization and embryonic survial
Single nucleotide polymorphic site at position 11646 of the bovine FGF2 gene is associated with improved fertilization rate and/or improved embryo survival rate, as well as improved milk production. Also disclosed are nucleic acid molecules, kits, methods of genotyping and marker assisted bovine breeding methods.
US08067168B2 Gene methylation in cancer diagnosis
The present invention provides DNA biomarker sequences that are differentially methylated in samples from normal individuals and individuals with cancer. The invention further provides methods of identifying differentially methylated DNA biomarker sequences and their use in detecting and diagnosing cancer.
US08067166B2 Chromosome 1p36 polymorphisms and low bone mineral density
The invention provides methods and compositions for diagnosing risk of low BMD and risk of osteoporosis based on the detection of SNP identity for human chromosome 1p36 polymorphisms designated in the NCBI SNP database (dbSNP) as rs2794328, rs446529, rs397559 and rs1802353.
US08067163B2 Determination of the biological function of a target gene in a cell
Disclosed herein is a method to determine the biological function(s) of a target gene in a cell, the steps of which involve separately culturing a first population and a second population of the cell under same culturing conditions, the first population of the cell differing from the second population of the cell in that the first population of the cell has accepted the introduction of a methylated polynucleotide; comparing the first population and the second population of the cell to determine which biological difference(s) is/are present therebetween; and determining which biological function(s) the target gene is associated with based on the determined biological difference(s) between the first population and the second population of the cell.
US08067162B2 Primer, primer set, and nucleic acid amplification method and mutation detection method using the same
The present invention provides a primer that effectively can detect, for example, the double helix structure of a nucleic acid. The primer is a labeled nucleic acid containing at least one structure represented by the following formula (16), where B is an atomic group having a nucleobase skeleton, E is an atomic group having a deoxyribose skeleton, a ribose skeleton, or a structure derived from either one of them, or an atomic group having a peptide structure or a peptoid structure, and Z11 and Z12 are each an atomic group that exhibits fluorescence and are identical to or different from each other.
US08067160B2 Genetic markers of schizophrenia
The invention includes method of determining if a subject has a genetic predisposition to clinically diagnosed schizophrenia (SZ), schizotypal personality disorder (SPD), and/or schizoaffective disorder (SD).
US08067151B2 Cold storage of pegylated platelets at about or below 0° C.
A method for storing and using platelets and an associated platelet structure. At least one modified platelet is formed. Each modified platelet includes a platelet and at least one polymerated chemical. Each polymerated chemical includes a polymer covalently bonded directly to the platelet or includes the polymer and a linker molecule such that the linker molecule is covalently bonded to the platelet and the polymer is covalently attached to the linker molecule. The polymer of each polymerated chemical of each modified platelet is polyethylene glycol (PEG) or a PEG derivative. Forming each modified platelet does not include modifying the platelet membrane of each platelet with a glycan-modifying agent. The at least one modified platelet is stored in a temperature range below 0° C. After being stored, the at least one modified platelet may be introduced into a subject to treat a condition related to a reduced platelet function.
US08067144B2 Polyesters for toner for electrophotography
The present invention relates to a polyester having an excellent hydrolysis resistance even when used in a process for producing a toner for electrophotography which includes a step of forming a raw material into particles in an aqueous medium, and a toner for electrophotography which contains the polyester and is excellent in storage stability and fixing property. There are provided a polyester for a toner for electrophotography which is used in a process for producing a toner including a step of forming a raw material component into particles in an aqueous medium or a solution, and produced by polycondensing an alcohol component with a carboxylic acid component containing at least one compound selected from the group consisting of an alkyl succinic acid and an alkenyl succinic acid, as well as a toner for electrophotography which contains the polyester.
US08067143B2 Functional particle and manufacturing method thereof
A functional particle is manufactured by a method including an aggregating step, a depressurizing step, and a cooling step. In the aggregating step, the functional particle is obtained by flowing a mixed slurry containing a core particle and a shell particle through a coiled pipeline while heating the mixed slurry to a glass transition temperature or higher of the core particle, to deposit the shell particles on the surface of the core particle. In the depressurizing step, the grain size of the functional particle is controlled and the coarse particle is pulverized to make the grain size of the functional particles uniform. In the cooling step, re-aggregation of the functional particles with unified grain size is prevented.
US08067138B2 Pyrrole containing photoconductors
A photoconductor that includes, for example, a supporting substrate, a photogenerating layer, and a charge transport layer, and wherein at least one of the charge transport layer and the photogenerating layer contains a pyrrole.
US08067132B2 Photomask and exposure method
To provide a photomask capable of preventing a foreign matter generation in using the photomask, and an exposure method using this photomask. The photomask includes a transparent substrate 2; a transfer pattern 4 formed in a main region 3 of a center portion of the transparent substrate 2; a light-shading band region 5 provided adjacent to the main region 3 in the outer peripheral region of the main region 3; and a pellicle 6 formed by adhering a pellicle film 6a to a pellicle frame 6b by an adhesive 8a, wherein this pellicle 6 is adhered onto a light-shading region 7 consisting of a light-shading film formed in the outer peripheral region of the main region 3, through an adhesive 8b.
US08067129B2 Electrolyte supported cell designed for longer life and higher power
A solid oxide fuel cell (SOFC) includes a cathode electrode, an anode electrode, and a solid oxide electrolyte located between the anode electrode and the cathode electrode. The cathode electrode is a porous ceramic layer infiltrated with a cathode catalyst material, and the anode electrode is a porous ceramic layer infiltrated with an anode catalyst material, and the electrolyte is a ceramic layer having a lower porosity than the anode and the cathode electrodes. A ceramic reinforcing region may be located adjacent to the riser opening in the electrolyte.
US08067128B2 Sealing structure of fuel cell and method for manufacturing the same
A sealing structure for a fuel cell and a method for manufacturing the same, in this structure, a first gas separator, a first gas diffusion layer and a first catalyst on the one side, a proton exchange membrane, a second catalyst, a second gas diffusion layer and a second gas separator on the other side, are in turn stacked, wherein an area of the second gas diffusion layer is smaller than an area of the proton exchange membrane. The area of the proton exchange membrane is not larger than an area of the first gas diffusion layer, and the area of the first gas diffusion layer is smaller than an area of the first gas separator, therefore, the shape of the front edges of these elements are step-shaped. The area obverse to the step shape is filled with cured sealing material.
US08067123B2 Fuel cell system and shutdown method of the same
At shutdown of a fuel cell system, a system-shutdown controller is configured to cause a current extraction device to extract current from a fuel cell in a state where a supply of a fuel gas through a fuel supply system is continued and a supply of an oxidant gas through an oxidant supply system is stopped, and the system-shutdown controller is configured to airtightly close fresh-air control valves after increasing pressure of the fuel gas in a fuel electrode to not less than atmospheric pressure and not less than pressure of the oxidant gas in an oxidant electrode.
US08067122B2 Fuel cell system
A fuel cell system is provided, the system comprising: a fuel cell (1) configured to generate electric power by use of a fuel gas; a reformer (2) configured to generate the fuel gas by reforming a raw material; a combustion burner (2a) configured to supply heat for reforming; a raw material feeder (10) configured to control the feed rate of combustion fuel to the combustion burner; a combustion fan (2b) configured to supply air to the combustion burner; a fuel gas passage (R1, R4); an off gas passage (R3, R5); a bypass passage (R2); a switching valve (8); and a controller (101), wherein the inside of the fuel cell is filled with the raw material before the fuel gas is supplied, and wherein the controller controls the raw material feeder so as to reduce the feed rate of the combustion fuel to the combustion burner when controlling the switching valve so as to shut off the bypass passage to supply the fuel gas generated in the reformer to the fuel cell. This fuel cell system is environmentally-friendly and capable of suppressing the emission of carbon monoxide at the start of a power generating operation to mitigate the adverse effect upon the ecosystem.
US08067113B2 Polymer battery module packaging sheet and a method of manufacturing the same
A polymer battery module packaging sheet includes, as essential components, a base layer (61), an aluminum layer (62), chemical conversion coatings (64a, 64b) coating the opposite surfaces of the aluminum layer (62), and an innermost layer (63). The chemical conversion coatings (64a, 64b) are formed by processing the opposite surfaces of the aluminum layer (62) by a phosphate treatment method. The base layer (61) and the innermost layer (63) are bonded to the chemical conversion coatings (64a, 64b) of the aluminum layer (62) with adhesive layers (65a, 65b), respectively.
US08067111B2 Battery module having battery cell assembly with heat exchanger
A battery module having a battery cell assembly with a heat exchanger is provided. The assembly includes a first battery cell having a first side and a second side, and a second battery cell having a first side and a second side. The first side of the second battery cell contacts the second side of the first battery cell. The assembly further includes a heat exchanger. A first side of the heat exchanger contacts the second side of the second battery cell. The battery cell assembly further includes a third battery cell having a first side and a second side. The first side of the third battery cell contacts a second side of the heat exchanger. The heat exchanger removes heat energy from the first, second, and third battery cells to maintain the first, second, and third battery cells at substantially a desired temperature.
US08067110B2 Organic vapor sorbent protective device with thin-film indicator
A sorbent media protective device includes an enclosure having a gas inlet, gas outlet and a thin-film multilayer indicator. The thin-film multilayer indicator is proximate sorbent media that can sorb a vapor of interest flowing from the gas inlet towards the gas outlet. The indicator includes a porous detection layer whose optical thickness changes in the presence of the vapor, located between a semireflective layer and a reflective layer permeable to the vapor. With equilibration at the applied vapor concentration between at least a portion of the media and the vapor, the vapor can pass through the reflective layer into the detection layer and change the detection layer optical thickness sufficiently to cause a visibly discernible change in the indicator appearance if viewed through the semireflective layer.
US08067108B1 Hybrid battery for use over extended temperature range
A hybrid battery comprising at least two nonaqueous electrochemical systems is described. The first cell comprises an anode of an alkaline earth metal or alloy thereof, and the second cell comprises an anode of an alkali metal or alloy thereof. The first cell is preferably an alkaline earth metal/oxyhalide cell, more preferably a calcium/oxyhalide cell or cells. The second cell is preferably an alkali metal alloy/oxyhalide cell, more preferably a lithium alloy/oxyhalide cell or cells. Such a cell combination is particularly useful for power a down-hole well tool. The down-hole tool is powered by the first cell during a surface test and as the tool descends into the well until all of the calcium is discharged. Then, the second cell powers the down-hole tool for the remainder of the down-hole procedure.
US08067101B2 Capacitor electrode and method of manufacturing the same
This invention relates to a capacitor electrode which includes porous layers made of a fiber and/or a whisker containing crystal tungsten oxides. The tungsten oxide fiber and/or whisker contain W18O49 as a main ingredient. The tungsten oxide fiber and/or whisker are made on a substrate. When manufacturing the capacitor electrode the substrate or its precursor is heated in vacuo or in an inactive containing a minute amount of oxygen, thereby completing the fiber and/or whisker.
US08067098B2 Sulfidation-resistant coating system
A coating system and process for protecting component surfaces exposed to sulfur-containing environments at elevated temperatures. The coating system includes a sulfidation-resistant overlay coating that is predominantly niobium or molybdenum.
US08067097B2 Woven laminate as lining for sound absorption of inlet and outlet sound absorbers and method of production of an acoustic insulation unit
A woven laminate for sound absorption that includes a first woven layer, a second woven layer, and a third woven layer. The first woven layer has a coarse structure. The second woven layer has a fine structure. The third woven layer has a medium structure. Each of the first, second, and third woven layers are composed of metallic wires that are woven to each other or interlaced as a fleece. At least one of the first, the second, and the third woven layers are superimposed in order to form the woven laminate. The woven layers are placed in the layer order fine-coarse-medium. The woven layers are welded together at least partially.
US08067096B2 Electrode material for electrolytic capacitor
There is provided an electrode material for electrolytic capacitor that attains an unprecedentedly high capacitance. The electrode material for electrolytic capacitor comprises a layer of valve metal particles furnished on the surface thereof with an oxide film, the layer having a porosity of 20 to 60% and a specific surface area of 30×103 to 400×103 cm2/cm3, wherein the valve metal particles are mixed together, with the particle diameters exhibiting a given distribution at least within the range of 0.005 to 0.1 μm, and form a base material surface, and wherein the valve metal consists of aluminum, and wherein the composition ratio of Al/O of the layer of valve metal particles furnished on the surface thereof with the oxide film is within the range of 2.0 to 5.5. The electrode material thus realizes high capacitance.
US08067094B2 Films including thermoplastic silicone block copolymers
A composite film includes a first film and a second film contiguous to the first film. The first film includes a light transmissive material. In one embodiment, the second film includes a polydiorganosiloxane polyamide block copolymer. In another embodiment, the second film includes a polydiorganosiloxane polyoxamide block copolymer.
US08067091B2 Dimensionally stable, leak-free graphite substrate
A method for preparing resin-impregnated graphite articles, including providing a sheet of compressed particles of exfoliated graphite having two major surfaces; impregnating the sheet with a first resin system to form a resin-impregnated sheet; surface treating the resin-impregnated sheet to form at least one structure on at least one of the major surfaces of the sheet to form a surface treated sheet; and treating the sheet with a second resin system.
US08067089B2 Cationic microcapsule particles
The present invention teaches a cationically charged or neutral microcapsule particle comprising an oil soluble or dispersible core material and a wall material at least partially surrounding the core material, the microcapsule wall material comprising the reaction product of a first composition in the presence of a second composition comprising an emulsifier which is cationic or nonionic, the first composition comprising a reaction product of i) an oil soluble or dispersible amine with ii) a multifunctional acrylate or methacrylate monomer or oligomer, an oil soluble acid and an initiator. The cationic or nonionic emulsifier comprises a water soluble or water dispersible material and optionally a water phase initiator. The first composition initiator and the water phase initiator is an energy-activated initiator. The reaction product of the first composition and second composition results in the formation of a population of microcapsules having a microcapsule wall of low permeance to the core material and having a zeta potential of −5 millivolts or greater. The resulting microcapsules have adherence to anionic surfaces.
US08067086B2 Matrix and layer system comprising non-stoichiometric particles
Protective layers, according to the prior art, achieve their protective function b depletion of a defined element that forms a protective oxide layer or that is exhausted as a sacrificial material. Once said material is exhausted, the protective function cannot be maintained. The invention is characterized by using particles (1) that contain a sustained-release depot of the exhaustible material. For this purpose, the material is present in a superstoichiometric form.
US08067084B2 Electromagnetic-wave shielding and light transmitting plate, manufacturing method thereof, and display panel
An electromagnetic-wave shielding and light transmitting plate 1 comprising an antireflection film 3, an electromagnetic-wave shielding film 10, a transparent substrate 2, and a near-infrared ray blocking film 5, wherein they are laminated and united by using intermediate adhesive layers 4A, 4B and a pressure-sensitive adhesive 4C, and the peripheries thereof are covered by a conductive sticky tape 7. The electromagnetic-wave shielding film 10 has a conductive foil 11 formed by pattern etching on a substrate film 13, is processed to have antireflection function by forming a light absorbing layer 12 on the conductive foil 11, and is subjected to a matting process to form small irregularities by roughening the surface of the light absorbing layer 12. A display panel is manufactured by bonding this electromagnetic-wave shielding film 10 to the front surface of a plasma display panel body. Accordingly, an electromagnetic-wave shielding and light transmitting plate and a display panel can be obtained which not only have excellent electromagnetic-wave shielding function but also provide high antireflection effect and have high level of transparency and high level of visibility, thereby providing distinct images.
US08067077B2 Webs and methods of making same
There are disclosed methods of making RFID transponder webs and intermediate webs such as RFID strap webs and antenna webs, as well as such webs per se.
US08067074B2 Article comprising light absorbent composition to mask visual haze and related methods
A transparent article includes a continuous polyester matrix having at least one incompatible filler dispersed therein. The incompatible filler provides domains in the polyester matrix, each domain having a particular dimension, thus providing a range of dimensions for the domains in the article. To create haze, the dimensions are within the range of from about 380 nm to about 720 nm. Once the range of dimensions is determined, a light absorbent composition can be found which absorbs light at a range of wavelengths that at least substantially covers the range of dimensions of the domains. In doing so, it has been found that the haze of the article can be substantially masked. Method for producing the article and for masking the haze are also provided.
US08067073B2 Thermoplastic medical device
An medical device such as a guidewire or a catheter having a flexible elongate component which comprises a thermoplastic rigid rod polymer, which component may comprise a bundle of threads, a sleeve, a coil, a co-extrusion, a strut, or other suitable component.
US08067072B2 Self opening bag stack and method of making same
A plurality of stacked polyethylene film bags comprising about 40-48 wt. % high density, high molecular weight polyethylene, 12-20 wt. % high density, medium molecular weight polyethylene, 20-30 wt. % linear low density polyethylene, 0-8 wt. % color concentrate, are releasably adhered together in substantial registration. Each of the bags includes front and rear polyethylene film walls and each of the front and rear walls have first and second side edges, a top edge and a bottom edge. The front and rear walls are integrally joined at their first and second side edges and secured together at their bottom edges. An open mouth portion is defined adjacent the top edges of the bag. At least an upper portion of the outer surface of the front and rear walls of each of the bags has been corona treated. T-shirt style bags using the above formulation are also described.
US08067067B2 Clean, dense yttrium oxide coating protecting semiconductor processing apparatus
Disclosed herein is a method for applying plasma-resistant coatings for use in semiconductor processing apparatus. The coatings are applied over a substrate which typically comprises an aluminum alloy of the 2000 series or the 5000 through 7000 series. The coating typically comprises an oxide or a fluoride of Y, Sc, La, Ce, Eu, Dy, or the like, or yttrium-aluminum-garnet (YAG). The coating may further comprise about 20 volume % or less of Al2O3. The coatings are typically applied to a surface of an aluminum alloy substrate or an anodized aluminum alloy substrate using a technique selected from the group consisting of thermal/flame spraying, plasma spraying, sputtering, and chemical vapor deposition (CVD). To provide the desired corrosion resistance, it is necessary to place the coating in compression. This is accomplished by controlling deposition conditions during application of the coating.
US08067064B2 Removable two-part glaze and textured paint system for decorative finishing
A process for making a faux finish with a two-part reactive system of materials includes providing a base material liquid of Poly Vinyl Acetate resin and water mixed with a dry powder functional filler and adding an activator liquid to the base material liquid. The activating liquid is a mixture of water and muriate of potash or boric acid product.
US08067060B2 Method for depositing a polymer layer on a surface of a support comprising at least a recessed zone
A polymer layer is deposited on a surface of a support, said surface comprising a flat main part and at least one recessed zone with respect to the flat main part. The polymer layer is achieved by at least the following successive steps: deposition of a predetermined quantity of a liquid mixture comprising at least a polymer or at least a precursor of said polymer on the flat main part of the surface of the support, introducing at least a part of the liquid mixture into the recessed zone by moving a cylinder placed on the flat main part of the surface, deposition of an additional quantity of liquid mixture on the flat main part of the surface, and rotation of the support along an axis perpendicular to the plane of the surface.
US08067056B2 Method for producing tamper-proof identification elements
The invention relates to a method for producing tamper-proof identification elements, and to tamper-proof identification elements produced according to said method and consisting respectively of at least one layer (2) reflecting electromagnetic waves (3), a spacer layer, and a layer consisting of metallic clusters (4). According to said method, a partial or all-over layer reflecting electromagnetic waves is applied to a carrier substrate (1), followed by at least one partial and/or all-over polymer layer having a defined thickness (3), and a layer consisting of metallic clusters which is produced by means of a method using vacuum technology or from systems based on solvents is then applied to said spacer layer(s).
US08067048B2 Method and apparatus for cooking low fat French fries
The present invention provides an apparatus and method for cooking French fries without cooking oil. The apparatus relies on high pressure inert gas at high temperature as the cooking medium. The inert gas acts both as a heat transfer medium to cook the potatoes, and as a protective atmosphere to prevent charring and oxidation of the potatoes.
US08067047B2 Method and devices for forming articles
The present invention is predicated upon methods and devices for forming numerous articles for various applications including nutritional applications, medicinal applications, or other useful applications for plants, animals or otherwise. In one aspect, the present invention provides methods and devices for forming high quality pellets using alginates as a retention agent for the ingredients. This may be achieved through the creation or modification of pre-existing forming devices, wherein an alginate applicator is provided for applying the alginate to the ingredients, before, during or after formation of the articles, or combinations thereof, to retain the ingredients of the articles together.
US08067046B2 Oral pouch product including soluble dietary fibers
Provided is an oral pouch product including a pouch having a plurality of pores. At least one portion of soluble dietary fibers is contained in the pores of the pouch and/or coated thereon. The oral pouch product is filled with a botanical material. The oral pouch product is placed in the mouth to release the soluble dietary fibers directly into the user's mouth.
US08067045B2 Nutritional formulations and associated methods
Nutritional formulations and methods for imparting positive health benefits to a subject are disclosed and described. In particular, methods and nutritional formulations for providing increased absorption of antioxidants are taught. In some aspects, the nutritional formulation can include Gac fruit extract in combination with at least one other antioxidant. Such nutritional formulations can in some respects produce enhanced or synergistic results with respect to the amount of antioxidants absorbed by a subject.
US08067043B2 Herbal composition for treatment of hyperlipidemia and the inhibition of myocardial infarction
A pharmaceutical or medicinal herbal composition and method of making the composition comprised of a mixture of the following herbal ingredients: Glycine max, Plumbago zeylanica, Terminalia arjuna, Trigonella-foenum-graceum, Coleus forskohlii, Commiphora mukul, Camellia sinensis, and Azadirachta indica.
US08067042B1 Megestrol acetate products, method of manufacture, and method of use
Disclosed herein is a method of using megestrol acetate. In one embodiment, the method comprises informing a user that megestrol acetate is metabolized by a cytochrome p450 isozyme. In another embodiment, the method comprises obtaining megestrol acetate from a container associated with published material providing information is metabolized by a cytochrome p450 isozyme. Also disclosed are articles of manufacture comprising a container containing a dosage form of megestrol acetate, wherein the container is associated with published material informing that megestrol acetate is metabolized by a cytochrome p450 isozyme, a method of treatment, and a method of manufacturing a megestrol acetate product.
US08067038B2 Ophthalmic composition for soft contact lens comprising terpenoid
Disclosed is an ophthalmic composition for a soft contact lens, which is characterized in that the adsorption of a terpenoid contained in the composition onto a soft contact lens is reduced. The ophthalmic composition comprises a combination of Component (A) 0.005 to 0.01 wt % of a terpenoid and Component (B) alginic acid and/or a salt thereof.
US08067037B2 Trehalose-containing topical drying composition and method of using same
A topical drying composition is providing containing trehalose as the effective moisture (sweat) removing ingredient. The composition may be used in aqueous form or preferably as a cream and in addition to trehalose it contains several ingredients such as sorbitan monolaurate, polysorbitan, a moisturizer, a thickener, a softener, an antibacterial agent and a pH adjusting component to adjust the pH of the composition between about 5.5 to about 7.5. Sterilized water is used as the carrier for the composition.The topical composition can be applied to the area which is vulnerable to sweating after vigorous exercise in order to moisturize sweating on the skin.
US08067033B2 Stable compositions of famotidine and ibuprofen
Stable pharmaceutical compositions of famotidine and ibuprofen in a single unit dosage form are disclosed herein. The compositions comprise a famotidine core having a reduced or minimal surface area surrounded by a layer of ibuprofen. In some embodiments, the ibuprofen is in direct physical contact with the famotidine.
US08067029B2 Rapidly disintegrating gelatinous coated tablets
The present invention relates to an improved gelatinous coated dosage form having two end regions coated with gelatinous materials and an exposed circumferential band. Openings are provided in at least the exposed band to reveal the core material. The invention also relates to methods for manufacturing such gelatinous coated dosage forms.
US08067026B2 Drug release regions for medical devices, which include polycyclic-structure-containing polymers
According to an aspect of the present invention, implantable or insertable medical devices are provided, which contain polymeric release regions that control the release of one or more therapeutic agents. The polymeric release regions, in turn, contain one or more polymers that contain one or more rigid, nonplanar polycyclic molecular structures. The therapeutic agent is disposed beneath or within the polymeric release region.
US08067023B2 Implantable medical devices incorporating plasma polymerized film layers and charged amino acids
An implantable medical device, such as a stent, is disclosed comprising an amino acid or a polypeptide bonded to a plasma polymerized film layer formed on the device. A method of manufacturing the same is also disclosed.
US08067022B2 Therapeutic inhibitor of vascular smooth muscle cells
Methods are provided for inhibiting stenosis following vascular trauma or disease in a mammalian host, comprising administering to the host a therapeutically effective dosage of a therapeutic conjugate containing a vascular smooth muscle binding protein that associates in a specific manner with a cell surface of the vascular smooth muscle cell, coupled to a therapeutic agent dosage form that inhibits a cellular activity of the muscle cell. Methods are also provided for the direct and/or targeted delivery of therapeutic agents to vascular smooth muscle cells that cause a dilation and fixation of the vascular lumen by inhibiting smooth muscle cell contraction, thereby constituting a biological stent. Also discussed are mechanisms for in vivo vascular smooth muscle cell proliferation modulation, agents that impact those mechanisms and protocols for the use of those agents.
US08067015B2 Methods and compositions for the treatment and prevention of Staphylococcus and other bacterial infections
The invention features methods and compositions for treatment or prevention of infection by, or disease caused by infection with, certain species of bacteria, including in particular bacteria in which a RAP-type and/or TRAP-type molecule plays a role in pathogenesis. This includes Staphylococcus species.
US08067013B2 Multivalent avian influenza vaccines
A vaccine composition and method which is effective in preventing or ameliorating Avian Influenza Virus infection is set forth herein. The vaccine contains at least two inactivated strains of avian influenza virus, wherein the combined haemoagglutinin (HA) total is at least about 200 HA/dose of the vaccine composition, and wherein each of the strains presents at least about 128 HA/dose, and further wherein one of the strains has the same HA subtype as that of a challenge virus, and wherein at least one of the strains has a different NA subtype than the challenge virus.
US08067012B2 Treatment of melanoma using HSV mutant
Use as an anti-cancer agent of a mutant herpes simplex virus wherein the mutant virus comprises a modification in the γ34.5 gene in the long repeat region (RL) such that the γ34.5 gene is a non-functional, manufacture of medicaments and methods of testing cancer in mammals employing HSV mutant.
US08067010B2 Immunological herpes simplex virus antigens and methods for use thereof
The invention provides HSV antigens that are useful for the prevention and treatment of HSV infection. Disclosed herein are antigens and/or their constituent epitopes confirmed to be recognized by T-cells derived from herpetic lesions or from uterine cervix. T-cells having specificity for antigens of the invention have demonstrated cytotoxic activity against cells loaded with virally-encoded peptide epitopes, and in many cases, against cells infected with HSV. The identification of immunogenic antigens responsible for T-cell specificity provides improved anti-viral therapeutic and prophylactic strategies. Compositions containing antigens or polynucleotides encoding antigens of the invention provide effectively targeted vaccines for prevention and treatment of HSV infection.
US08067009B1 Metalloproteinase oligopeptides and their therapeutic use
The invention discloses identification and therapeutic use of matrix metalloproteinase oligopeptides and peptidomimetics. The oligopeptides are used for making antibodies. The antibodies are used for diagnostic and treatment purposes of various diseases. In particular, the diseases may involve the mechanism of degradation of extracellular matrix by MMP's during cell proliferation cycle. Suppression of MMP activity seems to arrest tumor growth during cancer progression. MMP oligopeptides were used as vaccines to treat mice having murine melanoma B16FO induced tumor. There was a significant drop in tumor weight and size for the group of mice that were immunized with MMP oligopeptide.
US08067007B2 Compositions and methods for identifying and targeting cancer cells of alimentary canal origin
Screening and diagnostic reagents, kits and methods for primary and/or metastatic stomach or esophageal cancer are disclosed. Compositions for and methods of imaging and treating primary and/or metastatic stomach or esophageal cancer are disclosed. Vaccines compositions and methods of for treating and preventing primary and/or metastatic stomach or esophageal cancer are disclosed.
US08067005B1 Divalent antibody fragments
Divalent antibody fragments are described, each of which has one or more interchain bridges containing a synthetic or naturally occurring polymer selected from a polyalkylene, polyakenylene, polyoxyalkylene or polysaccharide. Each bridge may be the residue of a homo- or heterobifunctional cross-linking reagent and serves to link two heavy chains in each antibody fragment via the sulphur atoms of cysteine residues present in the chains. Each fragment may be attached to one or more effector or reporter molecules, and is of use in therapy or diagnostics where it has markedly improved binding and/or pharmacokinetic properties when compared to other antibody fragments which have the same number and type of polymer molecules but in which the polymer molecules are randomly attached.
US08067003B2 Methods of treating conditions using anti-IL-6 antibodies
Anti-IL-6 antibodies are used to treat IL-6 related conditions, such as rheumatoid arthritis, osteoarthritis, osteolysis, aseptic loosening of orthopedic implants, systemic lupus erythematosus, cutaneous lupus erythematosus, lupus nephritis, type 2 diabetes mellitus, chronic obstructive pulmonary disease, and renal cell carcinoma.
US08066998B2 Antibodies for norovirus
Norovirus antigen peptides are described having an amino acid sequence selected from the group consisting of SEQ ID NOS: 1-16, or fragments thereof. Such peptides can be used in the preparation of antiviral therapies such as vaccines, methods of preparing antibodies to the antigen peptides, methods of using the peptides or the corresponding antibodies for detection of norovirus, and compositions of the peptides, DNA and/or antibodies. A kit for the detection of norovirus is also provided.
US08066994B2 Proteins comprising an IgG2 domain
Disclosed are methods and compositions for efficiently expressing antibody fusion proteins. Antibody fusion proteins of the invention include a hybrid antibody moiety containing sequences from more than one type of antibody and/or mutant antibody sequences. Hybrid antibody fusion proteins of the invention may be produced at high levels and may combine functional properties characteristic of different antibody types in addition to functional properties of a non-antibody moiety.
US08066989B2 Method of treating tumor growth and metastasis by using trifunctional antibodies to reduce the risk for GvHD in allogeneic antitumor cell therapy
The present invention refers to a method of treating tumor growth and metastasis in a mammal, the treating comprising administering allogeneic effector cells together with trifunctional bispecific or trispecific antibodies or a combination thereof having the following properties: a) binding to a T cell b) binding to at least one antigen on a tumor cell c) binding via their Fc portion in the case of trifunctional bispecific antibodies or via third specificity in the case of trispecific antibodies to Fc receptor positive cells; the antibodies redirecting the allogenic cells away from host tissues in order to substantially reduce or avoid a graft versus host disease.
US08066986B2 Formulations including digestive enzymes and polysorbate surfactants that enhance the colonization of administered probiotics microoganisms
Disclosed are formulations for enhancing the in vivo colonization of probiotic microorganisms that include digestive enzymes and probiotic microorganisms, and polysorbate surfactants. The enzymes include lactogenic enzyme formulations that promote growth of Lactobacillus probiotics, bifidogenic enzyme formulations that promote growth of Bifidobacterium probiotics and combination formulations that benefit both types of probiotics. It has been discovered that certain polysorbate surfactants, including polysorbate-60 and polysorbate-80, further promote probiotic microorganism growth, when used with the enzyme formulations. The formulations are preferably compounded as dry powders, to avoid water reaction with the enzymes in blended formulations. Such formulations can be contained in capsules, tablets, packets or bottles and administered orally, either sequentially or in one combined formulation.
US08066984B2 Modified vaccinia virus strains for use in diagnostic and therapeutic methods
Modified viruses and methods for preparing the modified viruses are provided. Vaccines that contain the viruses are provided. The viruses can be used in methods of treatment of diseases, such as proliferative and inflammatory disorders, including cancer, and as anti-tumor and/or antiangiogenic agents. The viruses also can be used in diagnostic methods.
US08066980B2 Osteogenic synthetic peptides, pharmaceutical compositions comprising the same, and medium containing the same
Disclosed herein is an osteogenic synthetic peptide, derived from bone morphogenetic protein-7, consisting of a sequence of 15 amino acid residues. Provided are also a pharmaceutical composition and a medium composition comprising the same. Having remarkable activity related to promoting osteoblast differentiation, the osteogenic synthetic peptide is very useful in the treatment of osteoporosis, bone defects and/or osteoarthritis.
US08066978B2 Biopolymer and gene complex
Disclosed herein is a biopolymer/gene complex for the aerosol delivery of a gene. The biopolymer/gene complex comprises a polyethyleneimine (PEI) having a substitution of glucose for at least a portion of the primary amino groups of the polyethyleneimine, and the content of the polyethyleneimine is 2-4 times the content of the gene. Also, disclosed is a lung cancer therapeutic agent comprising a biopolymer/gene complex including a polyethyleneimine (PEI) having a substitution of glucose for 30-40 mol % of the primary amino groups of the polyethyleneimine, and a gene encoding PTEN, in which the content of the polyethyleneimine is 2-4 times the content of the gene.
US08066975B2 Foaming composition for washing and treating hair and/or scalp based on an active principle
The invention concerns a foaming composition for washing and treating hair and/or scalp essentially characterized in that it contains in an aqueous medium: at least an active principle selected among corticoids and retinoids; at least an anionic surfactant; at least an amphoteric surfactant; and a pro-penetrating agent.
US08066974B2 Contrast agents
The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds. More specifically the iodine containing compounds are chemical compounds containing an aliphatic central moiety containing urea or urethane functions allowing for the arrangement of three iodinated phenyl groups bound thereto. The invention also relates to the use of such diagnostic compositions as contrast agents in diagnostic imaging and in particular in X-ray imaging and to contrast media containing such compounds.
US08066972B2 Altering memory by affecting staufen function
The present invention provides methods for screening a pharmaceutical agent for its ability to modulate long term memory formation, performance of a hippocampal-dependent cognitive task or STAUFEN function. The present invention also provides methods for modulating long term memory formation or performance of a hippocampal-dependent cognitive task by modulating staufen-dependent protein expression. The present invention further provides methods for treating a defect in long term memory formation associated with a defect in STAUFEN and methods for treating a defect in performance of a hippocampal-dependent cognitive task associated with a defect in STAUFEN.
US08066970B2 Contrast agents
The present invention relates to a class of compounds and to diagnostic compositions containing such compounds where the compounds are iodine containing compounds. More specifically the iodine containing compounds are chemical compounds containing an aliphatic central moiety containing hydroxyl groups allowing for the arrangement of three iodinated phenyl groups bound thereto.The invention also relates to methods employing such diagnostic compositions as contrast agents in diagnostic imaging and in particular in X-ray imaging and to contrast media containing such compounds.
US08066969B2 Preparation method of magnetic and metal oxide nanoparticles
This invention relates, in general, to a method of producing magnetic oxide nanoparticles or metal oxide nanoparticles and, more particularly, to a method of producing magnetic or metal oxide nanoparticles, which comprises (1) adding a magnetic or metal precursor to a surfactant or a solvent containing the surfactant to produce a mixed solution, (2) heating the mixed solution to 50-6001 C to decompose the magnetic or metal precursor by heating so as to form the magnetic or metal oxide nanoparticles, and (3) separating the magnetic or metal oxide nanoparticles. Since the method is achieved through a simple process without using an oxidizing agent or a reducing agent, it is possible to simply mass-produce uniform magnetic or metal oxide nanoparticles having desired sizes compared to the conventional method.
US08066967B2 System and method for the manipulation, classification sorting, purification, placement, and alignment of nano fibers using electrostatic forces and electrographic techniques
A system and method for the manipulation of nanofibers using electrostatic forces. The nanofibers may be provided in a liquid medium, and the nanofibers may be nano-scale (i.e. measured in nanometers). The process is sensitive to the charge properties of the nanofibers (charge could be inherent to material or the charge can be induced into the material through electrochemical means), and therefore may be used to sort or classify particles. The nanofibers may also be aligned according to electrical fields, and thus anisotropic effect exploited. Devices produced may be conductors, semiconductors, active electronic devices, electron emitters, and the like. The nanofibers may be modified after deposition, for example to remove charge-influencing coatings to further enhance their performance, to enhance their adhesion to polymers for use as composite materials or result in the adhesion of the material at the proper location on a variety of different surfaces.
US08066966B2 Filmy graphite and process for producing the same
A process for producing a filmy graphite includes the steps of forming a polyimide film having a birefringence of 0.12 or more and heat-treating the polyimide film at 2,400° C. or higher.
US08066963B2 Removal of particulates from the exhaust gas of internal combustion engines operated with a predominantly stoichiometric air/fuel mixture
The exhaust gas of internal combustion engines operated with a predominantly stoichiometric air/fuel mixture contains, as well as the gaseous hydrocarbon (HC), carbon monoxide (CO) and nitrogen oxide (NOx) pollutants, also ultrafine particulates. There is disclosed a catalytically active particulate filter, an exhaust gas cleaning system and a process for cleaning the exhaust gases of predominantly stoichiometrically operated internal combustion engines, as well as the gaseous CO, HC and NOx pollutants, also for removing particulates from the exhaust gas. The particulate filter comprises a filter body and a catalytically active coating consisting of two layers. Both layers contain alumina. The first layer contains palladium. The second layer contains rhodium. The latter is disposed above the first layer.
US08066962B2 Environment holding apparatus and environment control type analyzer
An environment holding apparatus includes: a first chamber that has an opening and holds a sample; a moving stage that is two-dimensionally moved with the first chamber being mounted thereon; and a first plane that includes an introduction port having a function of introducing gas adjusted to predetermined conditions into the first chamber from a pipe, and that is provided so as to cover the opening of the first chamber. The first plane is provided so as to be kept stationary regardless of a movement of the moving stage and the opening of the first chamber is two-dimensionally moved along the first plane by the movement of the moving stage.
US08066959B2 Automatic analyzer
An automatic analyzer capable of performing analysis in terms of a number of analysis items with high reliability through a simple operation. The automatic analyzer comprises a probe adapted to be moved on a circular arc path and capable of sucking or discharging a sample or reagent, a plurality of sample containers disposed at different positions on the path of the probe and containing different analyte samples, and a rotor capable of carrying a plurality of reagent cartridges. Each of the reagent cartridges comprises a photometric cuvette that is empty when not in use, and a reagent cuvette in which a reagent used for a particular analysis item is hermetically sealed. A two-dimensional code with information regarding the analyte type and analysis conditions, for example, is affixed to the reagent cartridge. The two-dimensional code information is read by a reading unit. Based on the information read from the reagent cartridge, a control unit identifies the sample container in which a analyte sample required by a particular reagent cartridge is contained, and causes the probe to be moved to that sample container. The sample in the sample container is sucked and then discharged into the photometric cuvette of the reagent cartridge. The control unit also causes the probe to suck the reagent in the reagent cuvette of the reagent cartridge and then causes the reagent to be discharged into the photometric cuvette.
US08066956B2 Delivery of an odor control agent through the use of a presaturated wipe
A wiping product is disclosed containing an odor control agent. In one embodiment, the wipe may comprise a pre-moistened wipe containing a wiping solution. The wiping solution can contain the odor control agent. The odor control agent may comprise inorganic oxide particles, quinone compounds, or activated carbon particles. The odor control agent can be present in the wipe and can be configured to transfer to an opposing surface. In one embodiment, the pre-moistened wipe can be used during diaper changing to reduce malodors given off by the diaper after being discarded.
US08066954B2 Plug flow reactor and polymers prepared therewith
A plug flow reactor having an inner shell 27 surrounded by outer shell 21 and having at least one annular flow passage 35 therebetween can be used to prepare compositions, including polymers. The plug flow reactor also includes inlet port 36, an outlet port 37 and a plurality of exchanger tubes 26 wherein the exchanger tubes are in fluid communication to the at least one annular flow passage. Polystyrene and high impact polystyrene can be prepared using the reactor.
US08066949B2 Scrubber for fluid coker unit
Fouling in the scrubber section of a fluid coker unit is reduced by providing perforated baffles to improve the uniformity of the gas flow profile in the scrubber by reducing the gas velocity of the cyclone outlet gases in the scrubber section of the unit. These baffles are located with the objective of reducing the rotational component of the gas flow in the scrubber created by the alignment of the gas outlets of the cyclones. The baffles are preferably located in the shed section of the scrubber and comprise upstanding perforated plates located at the periphery of the scrubber section to disrupt high velocity gas jets in the region of the interior wall of the scrubber.
US08066948B2 Reactor for the continuous and simultaneous production of different polyester products having adjustable variable viscosity, the progress of the process being regulated via the hydraulic drive system
A device for degassing a flowable, viscous and pasty product includes a reactor having a product inlet and a product discharge outlet. A plurality of rotors each defining a reaction zone are located side-by-side in the reactor and a separate driving system mounted outside of the reactor for rotating each rotor with each driving system being an hydraulic system.
US08066942B2 Integrated device for heating and oxygenating blood in an extracorporeal circuit
An integrated device for heating and oxygenating blood in an extracorporeal blood circuit, comprising a shell-and-tube heat exchanger module provided with a coupling to a blood supply line and with two couplings respectively for the intake and discharge of the water designed to exchange heat with the blood; ports are also provided for the passage of the blood toward an oxygenator module of the hollow-fiber type which is located at the peripheral region of the heat exchanger and is provided with a coupling to a blood discharge line; the device further comprises means adapted to direct the flow of blood along a turbulence-free path and with optimum distribution within the two modules.
US08066941B2 Apparatus and method for purifying water in a storage tank
A pressurized water tank having a head space includes a pump for recirculating the water through a nozzle disposed in the head space. The out flowing stream of water will entrain air and cause mixing of air entrained water with the remaining water in the tank. To enhance air entrainment and convey the air entrained water to a location well below the water level, the stream of water is injected into a vertical venturi tube. The entrained air will have an oxidizing effect upon organic matter and also cause circulation of the water within the tank. To enhance oxidation of organic and inorganic matter, a UV lamp may be located in the head space to convert oxygen molecules in the air into ozone molecules. Such ozone molecules would be entrained in the stream of water flowing out of the nozzle and into the tube and have a strong oxidizing effect upon organic and inorganic matter. UV radiation from the UV lamp will also have a virucidal and germicidal effect upon microorganisms on the surface of the water and in water to some depth below the water surface.
US08066940B2 Apparatus and method for removing arsenic and inorganic compositions from water
Simultaneous application of ozone and ultraviolet light (UV185 and UV254) in water to be purified will create hydroxyl radicals, which combination will cause conversion of AS (III) that may be present to As (V), oxidation of inorganic matter such as manganese, sulfur, phosphorus and organic matter and provide virucidal and germicidal effects to purify the water.
US08066934B2 Process of confection of polyamide compounds with natural fibers and compounds of polyamides with natural fibers
The present invention relates to a process of production of polyamide compounds with natural fibers and polyamide compounds with natural fibers, establishes the fact of using natural fiber to obtain a compound with mechanical properties close to the one obtained with inorganic loads by means of continuous process with extrusion and molding by injection process; the processes presented allows the obtainment, by means of injection, of finished products with precise dimensional and complex features; the fact that the compound with natural Curauá fiber presenting suitable mechanical properties combined to a lesser density than the compound with inorganic load is interesting to the automotive industry as vehicles manufactured with lighter parts consume less fuel.
US08066932B2 Process of fabricating nanofibers by reactive electrospinning
Apparatus and methods for fabricating nanofibers by reactive electrospinning are described. An electrospinning process is coupled with an in-line reactor where chemical or photochemical reactions take place. This invention expands the application of the electrospinning and allows the production of nanofibers of crosslinked polymers and other new materials, such as gel nanofibers of ceramic precursors.
US08066930B2 Forming a layer on a substrate
The present invention is directed to a method of forming an imprinting layer on a substrate including high resolution features, and transferring the features into a solidified region of the substrate. Desired thickness of the residual layer may be minimized in addition to visco-elastic behavior of the material.
US08066925B2 Moulding process and product
In a moulding process for producing automobile parts, the female part (1) of a two part mould is sprayed with a metal such as stainless steel, tin, nickel-tin, copper or zinc. A thermal expansion compensation layer (3) is laid on the sprayed mould surface (1) and a layer of a resin impregnated fibrous material is applied thereto. The resultant assembly is cured and then removed from the female part of the mould or removed from the mould and then cured. The metal surface (2) of the composite part may be subject to further treatment such as polishing, coating and painting, or a combination of these. “Windows” may be produced by leaving areas of the mould part unsprayed with metal. In this way panels for lights, aerials or proximity sensors may be integrally formed.
US08066917B2 Photochromic curable composition
Disclosed is a photochromic curable composition comprising [A] not less than 0.1 part and less than 5 parts by mass of a specific radically polymerizable monomer having an epoxy group, [B] 1.0 to 15 parts by mass of a specific polyfunctional radically polymerizable monomer, [C] 1.0 to 30.0 parts by mass of a specific di(meth)acrylate monomer, [D] more than 50.0 parts and not more than 97.9 parts by mass of a (meth)acrylate monomer except the components [A] to [C] and/or a thio(meth)acrylate monomer, and [E] 0.001 to 10 parts by mass of a photochromic compound based on 100 parts by mass of the total of the polymerizable monomers.
US08066916B2 Synthesis of crystalline nanometric LiFeMPO4
The present invention relates to lithium secondary batteries and more specifically to positive electrode materials operating at potentials greater than 2.8 V vs. Li+/Li in non-aqueous electrochemical cells. In particular, the invention relates to crystalline nanometric olivine-type LiFe1-xMxPO4 powder with M is Co and/or Mn, and 0
US08066915B2 Composite carbonate and method for producing the same
The present invention provides a method for producing a nickel atom-, manganese atom- and cobalt atom-containing composite carbonate that is high in specific surface area and large in tap density, and useful as a raw material for producing a lithium nickel manganese cobalt composite oxide to be used in a positive electrode active material for use in a lithium secondary battery. The composite carbonate includes nickel atoms, manganese atoms and cobalt atoms, and has an average particle size of 5 μm or more and less than 20 μm, a BET specific surface area of 40 to 80 m2/g and a tap density of 1.7 g/ml or more.
US08066913B2 Li-Ni composite oxide particles for non-aqueous electrolyte secondary cell, process for producing the same, and non-aqueous electrolyte secondary cell
The present invention relates to Li—Ni composite oxide particles for a non-aqueous electrolyte secondary cell which have a large charge/discharge capacity, an excellent packing density and excellent storage performance. The Li—Ni composite oxide particles for a non-aqueous electrolyte secondary cell which have a composition represented by the formula: LixNi1-y-zCoyAlz02 in which 0.9
US08066912B2 Conductive pattern forming ink, conductive pattern, and wiring substrate
A conductive pattern forming ink for forming a conductive pattern on a substrate by a droplet discharge method, includes: metal particles; an aqueous dispersion medium in which the metal particles are dispersed; sugar alcohol derived from a disaccharide; and a polyglycerol compound having a polyglycerol skeleton. H shown in the following formula (I) is 0.10 to 0.80. H = OH ⁡ ( A ) Mw ⁡ ( A ) ⁢ X ⁡ ( A ) + OH ⁡ ( B ) Mw ⁡ ( B ) ⁢ X ⁡ ( B ) Formula ⁢ ⁢ ( I ) OH(A) represents an average number of hydroxyl groups in one molecule of the polyglycerol compound, Mw(A) represents a weight-average molecular weight of the polyglycerol compound, X(A) represents a content of the polyglycerol compound in the conductive pattern forming ink in weight percent; and OH(B) represents an average number of hydroxyl groups in one molecule of the sugar alcohol derived from a disaccharide, Mw(B) represents a weight-average molecular weight of the sugar alcohol derived from a disaccharide, and X(B) represents a content of the sugar alcohol derived from a disaccharide in the conductive pattern forming ink in weight percent.
US08066910B2 Phosphor and manufacturing method for the same, and light source
To provide a phosphor having an emission characteristic such that a peak wavelength of light emission is in a range from 580 to 680 nm, and having a high emission intensity, and having a flat excitation band with high efficiency for excitation light in a broad wavelength range from ultraviolet to visible light (wavelength range from 250 nm to 550 nm). For example, Ca3N2(2N), AlN(3N), Si3N4(3N), Eu2O3(3N) are prepared, and after weighing and mixing a predetermined amount of each raw material, raw materials are fired at 1500° C. for 6 hours, thus obtaining the phosphor including a product phase expressed by a composition formula CaAlSiN3:Eu and having an X-ray diffraction pattern satisfying a predetermined pattern.
US08066907B2 Liquid crystalline polyester resin composition, molded article and holder for optical pickup lenses
A liquid crystalline polyester resin composition is provided, by which a molded article with an enhanced specific modulus can be produced. The liquid crystalline polyester resin composition comprises mica fillers in an amount of 15 to 30 parts by mass and carbon fibers with specific volume resistance of 108 Ωcm or more in an amount of 5 to 20 parts by mass with respect to 100 parts by mass of the liquid crystalline polyester.
US08066901B1 Azeotrope-like compositions of trans-1,1,1,4,4,4-hexafluoro-2-butene and water
Provided are azeotropic and azeotrope-like compositions of trans-1,1,1,4,4,4-hexafluoro-2-butene (HFO-1336mzz(E)) and water. Such azeotropic and azeotrope-like compositions are useful in isolating HFO-1336mzz(E) from impurities during production. Azeotropes of the instant invention are similarly useful in final compositions, such as blowing agent, propellants, refrigerants, diluents for gaseous sterilization and the like.
US08066898B2 Surface treatment solution for the fine surface processing of a glass substrate containing multiple ingredients
A surface treatment solution for finely processing a glass substrate containing multiple ingredients is used for the construction of liquid crystal-based or organic electroluminescence-based flat panel display devices without invoking crystal precipitation and/or increasing surface roughness. An etching solution of the invention contains, in addition to hydrofluoric acid (HF) and ammonium fluoride (NH4F), at least one acid whose dissociation constant is larger than that of HF. The concentration of the acid in the solution can advantageously be adjusted to maximize the etching rate.
US08066896B2 Apparatus for etching wafer by single-wafer process and single wafer type method for etching wafer
An apparatus for etching a wafer by a single-wafer process comprises a fluid supplying device which feeds an etching fluid on a wafer, and a wafer-chuck for horizontally holding the wafer. The wafer-chuck is equipped with a gas injection device for injecting a gas to the wafer, a first fluid-aspirating device, and a second fluid-aspirating device. The etching fluid supplied on the wafer is spread by a rotation of the wafer. The etching fluid is scattered by a centrifugal force, or flows down over an edge portion of the wafer and is blown-off by the gas injected from the gas injection unit, and is aspirated by the first fluid-aspirating device or the second fluid-aspirating device.
US08066895B2 Method to control uniformity using tri-zone showerhead
Embodiments of the present invention provide apparatus and method for processing a substrate with increased uniformity. One embodiment of the present invention provides an apparatus for processing a substrate. The apparatus comprises a chamber body defining a processing volume, a substrate support disposed in the processing volume, a showerhead disposed in the processing volume opposite to the substrate support, and a plasma generation assembly configured to ignite a plasma from the processing gases in the processing gas in the processing volume. The showerhead is configured to provide one or more processing gases to the processing volume. The showerhead has two or more distribution zones each independently controllable.
US08066891B2 Wet etchable laminated body, insulation film, and electronic circuit part using the laminated body and the film
The present invention provides a laminate comprising an insulating layer having suppressed dusting properties, an insulating film comprising the insulating layer, and an electronic circuit component comprising a pattern of the insulating layer. The laminate has a layer construction of first inorganic material layer-insulating layer-second inorganic material layer or a layer construction of inorganic material layer-insulating layer. The insulating layer comprises a laminate of two or more wet etchable insulating unit layers. At the interface between the inorganic material layer and the insulating layer, surface irregularities of the inorganic material layer have been transferred onto the surface of the insulating layer. The average height of the surface irregularities transferred onto the insulating layer is less than the thickness of the outermost insulating unit layer in the insulating layer.
US08066889B2 Method for filtering cooking oil used in frying process
A method for filtering particulate material from cooking oil used in a frying process at a filtration temperature within the range of 250° F. to 400° F. includes providing a filter comprising a non-woven panel of directionally or randomly oriented fibers of synthetic material, and exposing the filter to the cooking oil at the filtration temperature while drawing the cooking oil therethrough.
US08066885B2 Process for the removal of impurities from carbonate minerals
A process for the beneficiation of carbonate mineral substrates by magnetic separation is defined herein wherein a phosphorus or nitrogen containing organic compound or reagent and a plurality of magnetic particles are intermixed with a carbonate containing mineral substrate, a magnetic field is applied to the mixture and a value mineral is thereby separated from a non-value mineral.
US08066883B2 Removing aluminum from solution using chelating compounds and immobilized tethered chelators
Methods are described for removing aluminum from a solution using novel di- and tripodal compounds as chelators.
US08066881B2 Method of obtaining a natural hydroxytyrosol-rich concentrate from olive tree residues and subproducts using clean technologies
A process of obtaining a natural, bioactive concentrate, rich on hydroxytyrosol, from olive tree residues and subproducts using clean technologies is presented. These technologies comprise supercritical fluid extraction, nanofiltration and reverse osmosis which are used individually or in an integrated mode. The natural extract comprises hydroxytyrosol at a minimum concentration of 15% (mass fraction) and a maximum concentration of 98% (mass fraction). The hydroxytyrosol-rich concentrate exhibits anti-oxidant, anti-microbial, anti-inflammatory and anti-carcinogenic activities, which are superior to the activities observed for isolated hydroxytyrosol in equivalent concentration. The hydroxytyrosol-rich concentrate can be prepared in the form of solid particles, as an aqueous solution, in an emulsion or as lipidic based nanoparticles. Industrial application includes the food, pharmaceutical and cosmetics industries.
US08066880B2 Apparatus for denitrifying wastewater
Disclosed is an apparatus for denitrifying a solution that includes a denitrification tank configured to receive a portion of the solution for a period of time. Controlling an amount, duration and frequency of introduction of polyethylene glycol into the solution promotes indigenous heterotrophic bacteria depleting dissolved oxygen in the solution and obtaining oxygen from nitrate in the solution.
US08066878B2 Anaerobic purification device
The invention relates to an anaerobic purification device for purification of influent. The device has a reactor tank, an inlet for introducing influent into the tank, a water collecting device for collecting purified water, a gas collecting system for collecting gas from the fluid contained in the reactor, a gas-liquid separation device, a riser for passing liquid into the separation device by gas lifting action caused by gas collected in the gas collecting system, and a downer for returning liquid and sludge from the separation device into the lower tank section. According to the invention this device is characterized in that it is arranged to define, in the downer at the level of the liquid surface, a head pressure of, at least, approximately 1.4 m water column (approximately 0.14 bar). The invention also relates to a method for anaerobic purification device for purification of influent.
US08066877B2 Apparatus for magnetic field and magnetic gradient enhanced filtration
This invention relates to various apparatus for carrying out cake-filtration solid-liquid separation processes in which the solid-liquid mixture is subjected to a homogeneous magnetic field, a magnetic field gradient or both and cake-filtration.
US08066876B2 Apparatus and methods for packing chromatography columns
A chromatographic apparatus may include a hydraulic lifting mechanism axially movable from a lowered position to a raised position such that a column and flange of the apparatus are axially movable with the hydraulic lifting mechanism. In a packing system, a mobile column module may be moved into engagement with a packing station by engaging a flange of the column module with a fixture of the packing station. After packing a column of the column module, the column module may be removed from the packing station with a piston head locked in the column to maintain packing pressure. The packing station may be utilized to unpack the column. A hydraulic lifting mechanism may be operated to lower one or more portions of the column module such that the one or more portions may be separately removed from the packing system.
US08066875B2 Flash chromatography cartridge
A low pressure liquid chromatographic cartridge is provided having a tubular polymer container adapted to receive a chromatographic packing material. The container has an outlet port located at a downstream end of the container and container threads formed on an upstream end of the container. A polymer cap having cap threads located on the cap threadingly engage the container threads. An inlet port is located on an upstream end of the cap. A flange depends from the cap and mates with the lip of the container to form a fluid tight seal between the polymer cap and container suitable for use in low pressure liquid chromatography. A locking tab on a skirt of the cap engages a recess on the container when the seal engages the cap and container to lock the cap in position relative to the container. Alternatively, continuous screw threads on the cap and container may hold the parts together.
US08066874B2 Apparatus for treating a flow of an aqueous solution containing arsenic
An apparatus for treating an aqueous solution containing arsenic. The apparatus comprises a container that includes a housing, an inlet located at a first end of the housing and an outlet located at a second end opposite the first end. An outer wall extends between the first and second ends and enclosing a fluid flow path between the inlet and the outlet and an arsenic fixing agent is disposed in the fluid flow path. The arsenic fixing agent can include an insoluble rare earth-containing compound, more specifically, a compound comprising one or more of cerium, lanthanum, or praseodymium. The inlet and the outlet are adapted to be closed during transport and storage. The container is adapted to be sealed for long term disposal after exposure to an aqueous solution containing arsenic.
US08066869B2 Process for deep desulphurization of cracking gasolines with a small loss of octane number
The invention relates to a treatment process of a sulphur-containing hydrocarbon fraction, comprising the following steps: a) a hydrodesulphurization step of said hydrocarbon fraction to produce a sulphur-depleted effluent, consisting of passing the hydrocarbon fraction mixed with hydrogen over at least one hydrodesulphurization catalyst. b) a step of separation of the partially desulphurized hydrocarbon fraction from the hydrogen introduced in excess, as well as the H2S formed in step a). c) a step of collecting both mercaptans and thiophenic compounds, consisting of placing the partially desulphurized hydrocarbon fraction originating in step b) in contact with an adsorbent comprising at least one element chosen from the group constituted by the elements of groups VIII, IB, IIB and IVA, the adsorbent being used in reduced form in the absence of hydrogen at a temperature above 40° C., the metal content in the reduced form of the adsorbent being above 25% by weight.
US08066862B2 Manufacturing method of wiring board
A manufacturing method of a wiring board includes a sticking layer forming step; a resist film forming step of forming a resist film on an upper surface of the sticking layer, the resist film having an opening exposing the upper surface of the sticking layer; a metal layer forming step of forming a metal layer, so as to cover an upper surface of the resist film and cover a side surface of the resist film and the upper surface of the sticking layer forming the opening for forming the wiring; a plating film forming step of filling with a plating film the opening for forming the wiring; a metal layer and plating film removing step; a resist film removing step; and a sticking layer removing step of removing the sticking layer of an unnecessary part not covered with the metal layer, after the resist film removing step.
US08066860B2 Arrangement of ion exchange material within an electrodeionization apparatus
An electrodeionization apparatus is provided comprising an ion-concentrating compartment partially bounded by an anion permeable membrane and also partially bounded by a cation permeable membrane, and a first ion exchange material domain disposed within the ion-concentrating compartment, wherein the first ion exchange material domain is contiguous with at least a portion of an ion-concentrating compartment side surface of one of the anion permeable membrane and the cation permeable membrane, and is spaced apart from the other one of the one of the anion permeable membrane and the cation permeable membrane. In the case where the one of the anion permeable membrane and the cation permeable membrane, having the at least a portion of an ion-concentrating compartment side surface with which the first ion exchange material domain is contiguous, is an anion permeable membrane, the first ion exchange material domain is an anion exchange material predominant domain. In the case where the one of the anion permeable membrane and the cation permeable membrane, having the at least a portion of an ion-concentrating compartment side surface with which the first ion exchange material domain is contiguous, is a cation permeable membrane, the first ion exchange material domain is a cation exchange material predominant domain.
US08066858B2 Analyte sensor with insertion monitor, and methods
A sensor, and methods of making, for determining the concentration of an analyte, such as glucose or lactate, in a biological fluid such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. The sensor includes a working electrode and a counter electrode, and can include an insertion monitoring trace to determine correct positioning of the sensor in a connector.
US08066855B2 Material and device properties modification by electrochemical charge injection in the absence of contacting electrolyte for either local spatial or final states
In some embodiments, the present invention is directed to processes for the combination of injecting charge in a material electrochemically via non-faradaic (double-layer) charging, and retaining this charge and associated desirable properties changes when the electrolyte is removed. The present invention is also directed to compositions and applications using material property changes that are induced electrochemically by double-layer charging and retained during subsequent electrolyte removal. In some embodiments, the present invention provides reversible processes for electrochemically injecting charge into material that is not in direct contact with an electrolyte. Additionally, in some embodiments, the present invention is directed to devices and other material applications that use properties changes resulting from reversible electrochemical charge injection in the absence of an electrolyte.
US08066851B2 In-line treatment of hydrocarbon fluids with ozone
A system for treating recovered fluids in-line that includes a thermal reactor for separating contaminated drill cuttings into drill cuttings and contaminants by applying heat to the contaminated drill cuttings so as to vaporize contaminants from the contaminated drill cuttings; a first condenser in fluid connection with the thermal reactor for condensing the vaporized contaminants; a separator in fluid connection with the first condenser for separating the condensed vapors into an oleaginous liquid and an aqueous liquid, wherein at least a portion of one of the aqueous liquid and oleaginous liquid is fed back into the first condenser via a feedback line; and an ozone generator operatively coupled to the feedback line, wherein at least the portion of the fed back liquid is ozonated by the ozone generator and fed into the condenser is disclosed.
US08066850B2 Apparatus to produce coated paper, cardboard or other fibrous webs with at least one thermo-sensitive layer and a method to operate an apparatus of this type
The invention relates to an apparatus to produce coated paper, cardboard or other fibrous webs with at least one thermo-sensitive layer as a functional layer through the application of at least one liquid or paste-like thermo-sensitive coating medium onto a carrier web by way of a unit which forms a functional layer, the units each include at least one applicator device and one drying section following the applicator device. The two units are capable of being installed in series and each form at least one functional layer on the carrier web, whereby in the merging area between the two functional layer forming units a web turning device is located, creating a first web path and a device to bypass the web turning device, thus creating a second web path for the carrier web between the two functional layer forming units. The invention further relates to a method to operate an apparatus of this type.
US08066849B2 Absorbent sheet prepared with papermaking fiber and synthetic fiber exhibiting improved wet strength
A wet-laid absorbent sheet includes a mixture of pulp-derived papermaking fibers and synthetic polymer fibers, a strength agent selected from carboxymethylcellulose and anionic starch as well as an epihalohydrin/amine functional wet strength resin. Also included is an anionic olefin copolymer resin effective to increase the wet/dry tensile ratio of the sheet.
US08066844B2 Compact wastewater concentrator using waste heat
A compact and portable liquid concentrator includes a gas inlet, a gas exit and a flow corridor connecting the gas inlet and the gas exit, wherein the flow corridor includes a narrowed portion that accelerates the gas through the flow corridor. A liquid inlet injects liquid into the gas stream at a point prior to the narrowed portion so that the gas-liquid mixture is thoroughly mixed within the flow corridor, causing a portion of the liquid to be evaporated. A demister or fluid scrubber downstream of the narrowed portion removes entrained liquid droplets from the gas stream and re-circulates the removed liquid to the liquid inlet through a re-circulating circuit. Fresh liquid to be concentrated is also introduced into the re-circulating circuit at a rate sufficient to offset the amount of liquid evaporated in the flow corridor.
US08066842B2 Method and apparatus for manufacturing a composite material
A method of manufacturing a composite material, the method comprising: providing a first layer (14) of CNTs reinforcement elements (13) with liquid matrix material in interstitial gaps between the reinforcement elements; dipping a second layer of reinforcement elements into the liquid matrix material in the interstitial gaps such that the reinforcement elements in the second layer become partially embedded in the first layer of reinforcement elements and partially protrude from the first layer of reinforcement elements, impregnating the protruding parts of the reinforcement elements in the second layer with liquid matrix material; and curing the liquid matrix material.
US08066839B2 Adhesive articles with improved air egress and methods of making the same
Methods of making adhesive articles providing air egress by supplying a route for the air to flow out from under the construction are described. One method includes providing a release liner comprising a moldable layer having a release surface and a back surface; applying a first pattern of a first non-adhesive material to a first portion of the release surface; applying a second pattern of a second non-adhesive material to a second portion of the release surface, wherein the second pattern partially overlaps the first pattern; embedding at least one of the first or second non-adhesive materials into the moldable layer; and transferring an adhesive layer having a front and back surface and end edges onto the release liner, wherein the front surface of the adhesive layer is adhered to the release surface of the release liner.
US08066835B2 Method and apparatus for the production of mitered corner joints by vibration welding
A method and an apparatus are described for the production of a mitered corner joint between parts of a frame, by vibration welding. During the welding procedure, in each case two parts of a frame are displaced by oscillatory heads into mutually perpendicular straight-line translatorial oscillations, the phases of which have been matched to one another in such a way that mitered areas of the two parts of the frame oscillate perpendicularly with respect to a stationary mitered plane and through the same, while the mitered area is retained under a prescribed welding pressure in the system. The method and the apparatus can be used for the simultaneous production of the four corner joints of a frame, in particular of a frame of the moveable or fixed part of windows or of doors. For this, at least four, and preferably eight, oscillatory heads, which displace the parts of the frame into the translatorial oscillations, are synchronized in such a way that their frequencies and amplitudes are the same.
US08066832B2 Delay compositions and detonation delay device utilizing same
A delay composition for a detonator or delay device. The composition comprising a mixture of silicon and barium sulfate, and an amount of red lead in the range of about 3 to 15%, and preferably 6 to 12%, by weight of the mixture. The invention also relates to a delay element comprising a rigid metal tube containing the delay composition, and a delay device incorporating the delay element.
US08066822B2 Dish washing machine having a steam generator and an over-pressure prevention feature
Dish washing machine including a steam generator. The dish washing machine also includes a tub that defines a dish washing space therein. A water supply supplies water to the steam generator, and a steam flow conduit guides steam, generated by the steam generator, to the dish washing space. An over-pressure prevention conduit having one end connected to the water supply conduit and the other end connected to either the steam flow conduit or the tub. The over-pressure prevention conduit prevents water in the steam generator from flowing backward into the water conduit and/or the public water supply when a reverse water pressure condition occurs.
US08066821B2 System for limiting pressure in a fine filter chamber for a dishwasher
A dishwasher includes wash chamber, a wash system for supplying washing fluid to wash arms to clean articles arranged in the wash chamber, and a washing fluid manifold having an inlet portion, an outlet portion and a passage interconnecting the inlet and outlet portions. A filter chamber is fluidly connected to the washing fluid manifold for removing food soil from the washing fluid. A venturi is provided in the passage for establishing a low pressure region. A sampling port for feeding the filter chamber is located in the low pressure region. In addition, a bleed port is provide near an inlet of the filter chamber. In this manner, washing fluid enters the filter chamber at low pressure to increase the efficiency of a filtering process, while washing fluid enters the wash arms at a high velocity to efficiently perform a washing operation.
US08066817B2 Method and apparatus for reducing deposits in fluid conduits
Methods and apparatus for reducing deposits from a petroleum flow line are disclosed. An embodiment of an apparatus for removing deposits from a petroleum flow line may include a pipe capable of being attached to a petroleum flow line. The pipe may have a pipe axis that defines a direction for fluid flow in the petroleum flow line. The apparatus may also include a first and a second field winding circumferentially disposed around the pipe, and an electric wave generator adapted to electrically communicate an electric wave to the first field winding and the second field winding. In response to the electric wave, the first field winding is adapted to produce a first magnetic field having a first magnetic axis and the second field winding is adapted to produce a second magnetic field having a second magnetic axis. The first magnetic axis may be noncollinear with respect to the second magnetic axis, and at least the first magnetic axis may be noncollinear with respect to the pipe axis.
US08066810B2 Lamellar zirconium phosphate
The present invention provides a crystalline layered zirconium phosphate, which is an ion exchanger particle excellent in heat resistance and chemical resistance, and utilizable as an impurity ion trapping agent for electronic materials, a raw material for antibacterials, a deodorant, a discoloration inhibitor, a rust preventive and the like, and which is also excellent in various processabilities.As a result of exhaustive studies to solve the problems, the present inventor has found a novel layered zirconium phosphate represented by the general formula (1) shown below: Zr1-xHfxHa(PO4)b.nH2O  (1) wherein a and b are positive numbers satisfying 3b−a=4; b is a number satisfying 2
US08066808B2 Ink set for ink-jet recording
An ink set for ink-jet recording includes a plurality of color inks, wherein the following formulae (a) to (d) are satisfied. Light OD reduction rate (X %)=[(A−B)/A]×100  (a) Ozone OD reduction rate (Y %)=[(C−D)/C]×100  (b) Total OD reduction rate (Z %)=X+Y
US08066807B2 Fire-resistant and insulating additives for building materials, their methods of production and uses thereof
Flame-retarding additives that may also have insulating properties are disclosed that include at least one carbonate salt, and at least one additional salt, active ingredient or combination thereof. In addition, methods of forming flame-retarding additives are disclosed that include providing at least one carbonate salt, providing at least one additional salt, active ingredient or combination thereof; and combining the at least one carbonate salt along with the at least one additional salt, active ingredient or combination thereof to form the flame-retarding additive. Flame-retarding additives disclosed may also comprise at least one filler material, including sand or white sand. These additives may also be included in paints and a number of processed building materials.
US08066805B2 Metal inks, methods of making the same, and methods for printing and/or forming metal films
Printable metal formulations, methods of making the formulations, and methods of coating or printing thin films from metal ink precursors are disclosed. The metal formulation generally includes one or more Group 4, 5, 6, 7, 8, 9, 10, 11, or 12 metal salts or metal complexes, one or more solvents adapted to facilitate coating and/or printing of the formulation, and one or more optional additives that form (only) gaseous or volatile byproducts upon reduction of the metal salt or metal complex to an elemental metal and/or alloy thereof. The formulation may be made by combining the metal salt(s) or metal complex(es) and the solvent(s), and dissolving the metal salt(s) or metal complex(es) in the solvent(s) to form the formulation. Thin films may be made by coating or printing the metal formulation on a substrate; removing the solvents to form a metal-containing precursor film; and reducing the metal-containing precursor film.
US08066803B2 Vacuum cleaner filter bag
The invention relates to vacuum cleaner filter bag with a bag wall made of a filter material, wherein the bag wall and/or the interior of the vacuum cleaner filter bag comprise fibres containing a biopolymer and having an antibacterial effect and/or a powder produced from a biopolymer and having an antibacterial effect.
US08066801B2 Sweep air system for membrane air dryer
A membrane dryer includes a shell having an inner tube and an outer tube and a bundle of hollow fibers supported in the shell. A dryer air inlet into the hollow fibers and a sweep air outlet from the inner tube are at a first end of the shell. A dryer air outlet into the hollow fibers and a sweep air inlet from the inner tube are at a second end of the shell. The inner tube has a first set of circumferential openings into the sweep air space adjacent the first end of the shell and a second set of circumferential openings into the sweep air space adjacent the first end of the shell; and a second plug is in the inner tube between the first and second set of openings.
US08066798B2 Method for selecting a gas filtering structure
A method for selecting a filtering structure for a gas laden with particulates, said structure comprising a filtering part formed from a porous ceramic material and comprising at least one, and preferably a plurality, of porous walls, said method being characterized in that, starting from a first image of the surface of the wall, a processing operation is carried out on said first image comprising a morphological erosion by a structuring element in such a manner as to obtain a second characteristic image of the regularity and of the uniformity of the microstructure of said wall.Silicon carbide filtering structure obtained by application of said method.
US08066792B2 Apparatus, system, and method for insulating an exhaust aftertreatment component
According to one representative embodiment, an exhaust aftertreatment component that includes a housing that defines an interior cavity through which exhaust gas is flowable. The housing includes an inner body, an outer body, and a space defined between the inner and outer bodies. The component also includes an insulation pack that is positioned within the space. The insulation pack includes insulation media encapsulated by a flexible fabric. The insulation pack further includes an at least partially rigid member that has a rigidity greater than a rigidity of the insulation media and flexible fabric.
US08066790B2 Fluid filter cartridge and housing
A filter housing and filter cartridge engagement structure comprising a housing having at least one ramp adapted to engage lugs of the at least one filter cartridge.
US08066789B2 Continuous fine ash depressurization system
A system for depressurizing and cooling a high pressure, high temperature fine solid particles stream having entrained gas therein. In one aspect, the system has an apparatus for cooling the high pressure, high temperature fine solid particles stream having entrained gas therein and a pressure letdown device for depressurization by separating the cooled fine solid particles from a portion of the fine solid particles stream having entrained gas therein, resulting in a lower temperature, lower pressure outlet of solid particles for disposal or handling by downstream equipment.
US08066786B2 Coated abrasive disc and method of making the same
A coated abrasive disc has a backing comprising a synthetic woven fabric having a first major surface with a presize disposed thereon and a second major surface opposite the first major surface and having a backsize disposed thereon. The presize comprises a reaction product of a curable presize precursor comprising: at least one epoxy resin prepared by reaction of epichlorohydrin with at least one of bisphenol A or bisphenol F, polyfunctional (meth)acrylate, novolac resin, imidazole epoxy cure catalyst, dicyandiamide, and a photoinitiator. A glass woven fabric permeated with an at least partially crosslinked saturant is secured to the second major surface by a thermoplastic laminating adhesive disposed between the second major surface of the synthetic woven fabric and the glass woven fabric. A method of making the same is also disclosed.
US08066785B2 Process for recycling waste materials
The present invention provides a process which utilizes biodiesel and other high boiling esters containing short alkyl groups to produce liquid fuels from waste material. The waste material is added to a solvent having a predetermined cycle starting solvent volume. An energy source is introduced into the solvent for a predetermined time at a predetermined temperature and pressure to form a non-grindable product. The energy source is removed and the product is cooled to a predetermined temperature to produce the fuel. The invention also encompasses the fuel formed by the process described.
US08066783B2 Solid electrolytic capacitor and manufacturing method therefor
A solid electrolytic capacitor of the present invention includes an anode element made of a sintered body of a valve-action metal; a dielectric coating, a solid electrolyte layer, and a cathode lead layer, sequentially formed on a surface of the anode element; and an anode lead member made of a conductive metal projecting from the anode element, the anode lead member having a base end thereof embedded in the anode element, the base end being formed such that a cross section thereof perpendicular to a direction extending inwardly of the anode element has a contour with four rounded rectangular corners.
US08066779B2 Modular hip joint implant
A modular hip joint implant and associated method. The modular hip implant includes a femoral stem having a proximal surface defining a dovetail groove having first and second female wings, and a neck component having a distal surface defining a semi-dovetail projection engaging the dovetail groove. The projection includes a single male wing mating with the first femoral wing.
US08066777B2 Method and apparatus for wrist arthroplasty
A wrist prosthesis system to replace at least a portion of a bone of a wrist of a patient. The system includes a carpal implant to replace at least a portion of a carpal bone of a carpal complex of the patient. The carpal implant includes a base and an augment that replaces at least a portion of the carpal bone. The augment is removably coupled to the base.
US08066774B2 Artificial disc implants and associated methods and instrumentation
An artificial disc implant and associate methods and instrumentation are provided for the artificial disc implant that includes opposite vertebral endplate members and a spacer member between the vertebral endplate members. An anchoring member extends from at least one of the vertebral endplate members toward an adjacent vertebral endplate when the implant is positioned between vertebrae. The anchoring member can be received in an anchor seat formed in the adjacent vertebral endplate without requiring the artificial disc implant to be impacted into the space between vertebrae to engage the anchoring member in the seat.
US08066773B2 Artificial intervertebral disc
An artificial intervertebral disc for at least partially replacing a diseased or damaged intervertebral disc. The artificial disc includes a concave-convex articulating surface. The artificial disc can be used in the cervical region of the spine, where a concave-convex articulating surface is advantageous for improved anatomical fit and region appropriate kinematics. The artificial disc of the present invention also includes an anchor for attachment to bone.
US08066772B2 Multiple facet joint replacement
A prosthesis for the replacement of multiple diseased or traumatized spinal facets comprises a portion that replaces at least a bony portion of the facets to be replaced and where the prosthesis attaches to the vertebra in a manner that does not require attachment to, or abutment against, the lamina. Multiple configurations of the prosthesis provide for replacement of the two inferior facets, the two superior facets, a superior and inferior facet, or all four facets. A method of installing the prosthesis is provided that is comprised of the steps of resecting at least a portion of the facets that carry the diseased or traumatized spinal facets and attaching the prosthesis in a manner that does not require attachment or abutment against the lamina.
US08066771B2 Facet arthroplasty devices and methods
A spinal prosthesis system having a caudal prosthesis provided with a pair of pedicle anchors for coupling to an inferior vertebral body, the caudal prosthesis including an artificial caudal facet joint structure comprising a pair of caudal bearing surfaces. A cephalad prosthesis is provided with a second pair of pedicle anchors for coupling to a superior vertebral body. The cephalad prosthesis includes an artificial cephalad facet joint structure having a pair of cephalad bearing surfaces. An artificial facet joint is formed between the adjoining vertebral bodies by articulation of the artificial caudal facet joint structure with the artificial cephalad facet joint structure.
US08066769B2 Intraocular lens system
The present invention discloses a multi-component intraocular lens implanted in an optical system of a human eye, including one or more foldable removable components, each component being foldable. One component acts as a base lens, including a flange with a slot. Another component acts is an optical assembly that may include a top lens joined to or integrated with a mid lens. The top lens, the mid lens or the optical assembly may include at least one projection that engages the slot of the base lens. The top and mid lenses are manufactured from a material having adhesive properties, wherein the top and mid lenses adhere to each other free of any material or substance being present therebetween.
US08066768B2 Intraocular lens system
A multi-component intraocular lens implanted in an optical system of a human eye includes one or more removable components, each component being foldable. One component acts as a base lens, including a flange with an aperture. Another component acts as a mid lens, including a tab which engages the aperture. A third component acts as a top lens, which engages the mid lens. Because the lens components are foldable, they may be inserted into the eye using an incision smaller than the diameter of the unfolded lens. The removable components may be used to correct various medical conditions of the eye, as well as to improve and enhance vision, and for cosmetic purposes.
US08066767B2 Intraocular lens
The invention concerns an intraocular lens with negative spherical aberration and a method of determining the refractive power of intraocular lenses. In the environment of immersion medium the intraocular lens refracts an incoming wave with an elliptically oblongly curved wave front into an outgoing wave with a substantially spherical wave front.
US08066766B2 Methods and devices for termination
Devices and methods used in termination of a tissue tightening procedure are described. Termination includes the cinching of a tether to tighten the tissue, locking the tether to maintain tension, and cutting excess tether. In procedures involving anchors secured to the tissue, the tether is coupled to the anchors and the tissue is tightened via tension applied to the anchors by cinching the tether. In general, the devices and methods can be used in minimally invasive surgical procedures, and can be applied through small incisions or intravascularly. A method for tightening tissue by fixedly coupling a first anchor to a tether and slidably coupling a second anchor to the tether, securing both anchors to the tissue, applying tension to the tether intravascularly, fixedly coupling the tether to the second anchor, and cutting the tether is described. The tissue to be tightened can comprise heart tissue, in particular heart valve annulus tissue. Various devices and methods for locking the tether in place and cutting excess tether are described.
US08066758B2 Vascular graft with kink resistance after clamping
A self-sealing vascular graft with kink resistance is described. The vascular graft includes a substrate that can be a PTFE, having a self-sealing region that may include several layers of material. The central section of the vascular graft may be constructed differently from surrounding self-sealing regions, in order to provide kink resistance following the clamping of the graft. Also described is a graft with a flared cuff attached to one or both ends, the attachment or transition region including reinforcement beading.
US08066754B2 Rolling membrane with hydraulic recapture means for self expanding stent
A medical device comprising a catheter having a retractable outer sheath and a rolling membrane. The catheter includes a catheter inner shaft about which a stent in a reduced diameter configuration may be disposed. A stent retaining region of the sheath is disposed about the stent to retain the stent in the reduced diameter state prior to delivery. The rolling membrane is engaged to a portion of the outer sheath at an engagement region. The rolling membrane is positioned between the catheter inner shaft and the outer sheath and prior to retraction of the sheath the rolling membrane is disposed about at least a proximal section of the stent and is rollingly retracted therefrom when the sheath is retracted to deliver the stent. The device also recaptures a stent by pressurizing a intra-catheter space, which results in the longitudinal movement of the outer sheath in a distal direction to recover and retain the stent.
US08066753B2 Specialized catheter and method for placement in a bifurcated vessel
A specialized catheter is used in a method to place a stent assembly in a bifurcated vessel in an animal body, such as a human. Primary and secondary guidewires are inserted from a location external of the body through the primary vessel, the secondary guidewire being further inserted into a secondary vessel beyond a bifurcation area. The guidewires are inserted into a primary stent and catheter assembly such that the assembly can move along the guidewires to the bifurcation area where the primary stent is expanded. While retaining the secondary guidewire in the vessels, the primary catheter assembly and primary guidewire are removed, the secondary guidewire passing through specialized openings in the primary catheter. Then the secondary stent, mounted on a catheter, is passed through the primary vessel guided by the secondary guidewire, and into the secondary vessel. There, the secondary stent is expanded to form the bifurcated stent assembly in an efficient manner.
US08066752B2 Methods and apparatus for adjusting body core temperature
A method and apparatus for adjusting body core temperature are provided. The apparatus comprises an appendage chamber that is adapted to be disassembled from a heat exchange element. In one aspect, the appendage chamber is disposable. The appendage chamber provides a negative pressure environment for a patient's appendage placed therein. An appendage is heated and exposed to a negative pressure environment within the apparatus to efficiently raise or maintain the body core temperature of the patient.
US08066745B2 Capless multiaxial screw and spinal fixation assembly and method
A spinal fixation assembly and capless multi-axial screw system and method are shown. The assembly comprises a receiver having a rotary lock which in one embodiment includes a plurality of channels which urge and lock the elongated member to the screw using a bayonet type connection.
US08066742B2 Intervertebral prosthetic device for spinal stabilization and method of implanting same
An intervertebral prosthetic device for spinal stabilization and a method of using same according to which a body member is implanted between two adjacent vertebrae so that a spinous processes of a vertebrae extends into a notch formed in the body member. A groove is also formed in the body member that engages one of the vertebrae.
US08066741B2 Prosthesis for the replacement of a posterior element of a vertebra
A prosthetic replacement for a posterior element of a vertebra comprising portions that replace the natural lamina and the four natural facets. The prosthetic replacement may also include portions that replace one or more of the natural spinous process and the two natural transverse processes. If desired, the prosthesis replacement may also replace the natural pedicles. A method for replacing a posterior element of a vertebra is also provided.
US08066739B2 Tool system for dynamic spinal implants
A tool set for implanting bone screws in a human spine, followed by the implantation of a longitudinal connecting member into the bone screws includes a pair of independently mountable and manipulatable elongate guide tools that form a unitary tool guide when desired. Each guide tool includes attachment structure for independent operable connection of the guide tool to an arm of the bone screw. The bone screw/guide tool attachment includes an undercut and/or recess so as to resist separation of the guide tool member from an attached bone screw. A removable stabilizer cooperating with the pair of guide tools places such tools in a set spaced relation to one another when desired. Further tools include a cooperating bone screw driver with an attached stabilizer, a closure starter/reduction tool, a closure driver and a counter torque tool.
US08066738B2 Pacifier
A pacifier includes an inner substrate layer and an outer substrate layer comolded over the inner substrate layer. The outer substrate layer forms a nipple and a handle. The inner substrate layer has a first portion covered by the outer substrate layer and a portion uncovered by the outer substrate layer forming a shield portion.
US08066734B2 Implant for the closing of defect openings in the body of a human or animal and a system for the placement of such an implant
To bring about an improvement in comparison with known implants, in particular with regard to economical mass production, an implant for the closing of defect openings in the body of a human or animal is proposed, with a load-bearing structure which, in a first operating state (primary form), has a great ratio of length to transverse extent along an axis and, at least in a further operating state (secondary form), has a much smaller ratio of length to transverse extent along the axis, the load-bearing structure being capable of being reversibly transformed from the secondary form into the primary form by exertion of a force against elastic material forces, the secondary form assuming approximately the form of a double disc with a proximal disc element and a distal disc element for receiving the surroundings of the defect opening between the disc elements, and the load-bearing structure being formed essentially in one piece without joining connections, and a placement system, in particular for such an implant, is proposed, with a stretching element and at least one, preferably two, holding wires, the stretching element serving for interacting with a distal end of an implant and the holding wire or wires serving for interacting with a proximal end of an implant, the implant being capable of being transformed from a primary form into a secondary form and vice versa by relative movement of the holding wires in relation to the stretching element.
US08066733B2 Inverting occlusion devices, methods, and systems
Described are devices, methods and systems useful for achieving occlusion of vascular vessels. Percutaneous procedures can be used to occlude and obliterate the greater saphenous vein, for example in the treatment of varicose vein condition caused by venous reflux. Certain embodiments encompass the percutaneous delivery of an occlusion device inverted within a cannula, its deployment and filling, so as to occlude or obliterate a portion of a vascular vessel.
US08066732B2 Inverting occlusion devices, methods, and systems
Described are devices, methods and systems useful for achieving occlusion of vascular vessels. Percutaneous procedures can be used to occlude and obliterate the greater saphenous vein, for example in the treatment of varicose vein condition caused by venous reflux. Certain embodiments encompass the percutaneous delivery of an occlusion device inverted within a cannula, its deployment and filling, so as to occlude or obliterate a portion of a vascular vessel.
US08066728B2 Disposable or single-use lancet device and method
Single-use lancet device includes a body. A movable skin engaging member is at least partially disposed inside the body and includes a lancet opening through which a lancet needle extends. A holding member can move at least between a retracted position and an extended position. The skin engaging member is structured and arranged to retract into the body. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way.
US08066726B2 Serpentine cutting blade for cutting balloon
A system for treatment of a vessel lesion comprises an expandable balloon and at least one cutting blade engaged to an exterior surface of the balloon. At least a portion of the cutting blade has a substantially serpentine configuration defined by a plurality of interconnected peaks and troughs wherein each trough is in closer proximity to the balloon than each peak.
US08066722B2 Clip applier
A clip applier includes a body 21, an insertion tube 22 extending from the body 21 and inserted in a channel of an endoscope and a clamp mechanism 24 disposed at a distal end of the insertion tube 22. The clamp mechanism 24 has a support member 28 fixed at the distal end of the insertion tube 22 and a pair of clamp members 30 rotatably supported by the support member 28. The clamp members 30 are connected to a distal end of a wire 25 via a pair of links 35. The clamp members 30 respectively include gripping portions 32 protruding form the support member 28. A clip 50 is received in receiving grooves 32a of the gripping portions 32. When the wire 25 is pulled by operating an operation member disposed on the body 21, the clamp members 30 are rotated against an elastic force of a hinge portion 51 of the clip 50, thereby causing a pair of clip portions 53 of the clip 50 to be opened.
US08066719B2 Apparatus and methods for forming gastrointestinal tissue approximations
Apparatus and methods are provided for forming a gastrointestinal tissue fold by engaging tissue at a first tissue contact point, moving the first tissue contact point from a position initially distal to a second tissue contact point to a position proximal of the second contact point to form a tissue fold, and extending an anchor assembly through the tissue fold near the second tissue contact point.
US08066717B2 Device and method for harvesting and implanting follicular units
Device and method for harvesting and implanting hair follicular units is provided. A combined harvesting and implanting tool or tool assembly provides a harvesting cannula portion detachably coupled to an implanting cannula portion. The harvesting and implanting cannula portions may be coupled by a connector that could be designed to allow for multiple uses of the tool assembly, or alternatively may be designed for single use and rendered non-functional when the implanting cannula portion of the tool is separated from the harvesting cannula portion of the tool.
US08066711B2 Internal bone fixation system with integrated mixer
Systems and methods for repairing a weakened or fractured bone are disclosed herein. A system for repairing a fractured bone includes a delivery catheter having an elongated shaft with a proximal end, a distal end, and a longitudinal axis therebetween, wherein the delivery catheter has an inner void for passage of bone cement components and an inner lumen for passage of a mixing element; an internal bone fixation device releasably engaging the distal end of the delivery catheter, wherein the internal bone fixation device moves from a first compact state to a second expanded state when the bone cement components are delivered to the internal bone fixation device and mixed within the internal bone fixation device; and a spinning mechanism engaged to a rotatable shaft, wherein the spinning mechanism is inserted into the internal bone fixation device.
US08066710B2 Distractor for posterior interbody fusion
A method and instrumentation for spinal interbody fusion is disclosed. The instruments and methods are particularly adapted for interbody fusion from a posterior approach to the spine. One instrument is a retractor having a lockable pivotally mounted handle. Another instrument is a template for straddling the dura. A modular distractor is also provided and preferably includes a tapered shaft with a visualization window disposed therein. Yet another instrument is a depth gauge to verify bone opening depth and dimension, preferably including a radiopaque portion. A method contemplates the use of these instruments to prepare a disc space to receive an implant.
US08066709B2 Distractor with opening
An apparatus and method for placing adjacent vertebrae at a fixed distance and angular relationship relative to each other, fixing said vertebrae in said position by use of a milling block engaging each of said adjacent vertebrae and then using a milling means, the depth, length and excursion of which from side to side are controlled by said apparatus to machine out a defined thickness of bone and a space of defined length, height, width and shape in preparation for receiving an interbody spinal implant or graft of known size and configuration are disclosed.
US08066704B2 Suction ablator
An improved electrode for electrosurgery comprises at least one orifice in the active surface of the electrode connected to a lumen in the probe of larger cross-sectional area than the area of the orifice(s), the lumen being connected to a vacuum, such that a venturi is formed extending from the one or more orifices in the active surface of the electrode to the lumen, whereby flow of fluid, ablated tissue, and other debris in the vicinity of the surgical site is accelerated through the orifice(s), reducing clogging, whereby any particle passing through the orifice(s) is unlikely to become clogged downstream, and whereby the edges of the orifice(s) are ablative, tending to reduce any particles caught at the orifice(s) to a size small enough to pass therethrough.
US08066699B2 Ultrasound ablation catheter and method for its use
Catheters and methods for epicardial ablation are provided. A suitable catheter comprises an elongated catheter body and an ultrasound transducer mounted at or near the distal end of the catheter body. The transducer has a front surface and an opposing back surface, wherein the transducer is positioned to transmit ultrasound energy toward tissue facing the front surface but not toward tissue facing the back surface. A sensor is mounted within the catheter near the ultrasound transducer for sensing a location and an orientation of the ultrasound transducer within a patient. A suitable method involves introducing the distal end of the catheter introducing into the pericardium of a patient. The transducer's front surface is positioned so that it generally faces tissue to be ablated, and the tissue is ablated with ultrasound energy generated by the transducer.
US08066698B2 Cryosurgery device
A cryosurgery device includes an aerosol container holding a liquid refrigerant and having a valve and a stem extending out therefrom; an actuator seated on the stem and including an outlet tube for receiving released refrigerant from the container; a hub mounted on the container and including slots therein; and a base having a central opening for receiving the hub, the base including aligning projections that enter the slots in the hub to engage and apply pressure to the actuator to cause the actuator to depress the stem and release refrigerant into the base. The container may further contain an applicator tube mounted to the hub in fluid communication with the outlet tube with a porous tip mounted to a distal end of the applicator tube for receiving the refrigerant and, being chilled thereby, applied to a skin lesion to be treated.
US08066688B2 Liquid drug medical device
The present invention relates to liquid drug medical devices for enabling the administration of liquid drugs, and also a needle shield removal device for safely removing needle shields.
US08066687B2 Side seam for disposable garment
The present invention relates to a disposable absorbent article comprising a chassis defining a front waist region, a rear waist region, and a crotch region disposed between the front waist region and rear waist region. The article includes front and back ear panels that are joined at opposing side seams. The side seam can include an initiation region, which can be bonded or unbonded, and a propagation region. The initiation region and the propagation region have a resistance to user-applied opening forces. The resistance at the initiation region is less than that of the propagation region. The seam can further include additional regions. The article can include a tab member that can be engaged by the user to facilitate opening of the seam.
US08066685B2 Stretchable absorbent article having lateral and longitudinal stretch properties
Absorbent articles with carefully controlled stretch properties are disclosed. In particular, the articles exhibit stretch not only in the lateral direction but also in the longitudinal direction. Specifically, the articles have a biaxial stretch ratio, which refers to a ratio of stretch along the hip circumference of the article to the amount of stretch in the longitudinal direction, that is from about 1.0 to about 2.5, and particularly from about 1.1 to about 1.5. Absorbent articles made in accordance with the present invention are capable of accommodating a relatively large size range of wearers. The articles also exhibit improved fit and prevent sagging or drooping of the crotch region, even after the crotch region has been wetted.
US08066683B2 Disposable diaper
A disposable diaper is provided, including an absorber, a top sheet, a back sheet, and a skin contact sheet (SCS) disposed above the top sheet. The skin contact sheet is formed with a stool passing opening and a urine passing opening at a portion corresponding to a crotch part, and includes an SCS central region formed by extending a strip-shaped inter-opening region, which is sandwiched by the two openings and extends in the width direction, by half the length between the openings in the anterior direction and in the posterior direction; an SCS ventral region located at the ventral side from the SCS central region; and an SCS dorsal region located at the dorsal side from the SCS central region. A least the SCS central region has the stretching force in the width direction, and an inter-opening central region sandwiched by the two openings includes a non-stretchable region.
US08066682B2 Eye drops container
An eye drops container including a container body filled with a drug solution along with a pressurized gas and including a valve mechanism discharging a fixed amount of drug solution; a nozzle member coupled with a stem for open operation of the valve mechanism and including a drug solution drop nozzle; an operating member including an operating piece and attached to the container body; a guide member contained in the operating member and guiding the nozzle member in the axial direction; and a ball contained in the guide member. The nozzle member includes an outer flange for suspending a skirt on the lower surface thereof; the guide member includes a ring-like bottom groove into which the forward end of the skirt enters; and the ball falls into the bottom groove in an upright state to block the open operation of the valve mechanism, and falls onto the outer flange in an inverted state to permit the open operation of the valve mechanism.
US08066681B1 Intracranial pressure monitor and drainage catheter assembly
A monitor-driven intracranial catheter assembly including dual lumen catheter for monitoring intracranial pressure via a pressure sensor located in one lumen while simultaneously draining cerebrospinal fluid through another lumen. A third lumen can also be provided with a side port for receiving a stylet. The stylet is used as a stiffening agent to aid in advancing the catheter into the patient's brain. The pressure sensor is preferably a spectral modulation sensor that communicates with a photodetector apparatus by means of a single optical fiber, thus minimizing the diameter of the catheter. The photodetector is self-correcting for signal errors caused by temperature change, changes in intensity of the input light, and transmission losses within the optical apparatus. Moreover, the photodetector operates off the output voltage of the standard hospital monitor by “scaling” the signal from the monitor to provide a pressure measurement signal that emulates the output of a piezoresistive strain gauge sensor or Wheatstone bridge. Therefore, the entire catheter assembly is designed to be used with any of the common types of hospital monitors. The pressure monitoring catheter assembly can be used in any situation requiring very sensitive pressure measurements and can be zeroed and calibrated in situ.
US08066678B2 Safety needle with collapsible sheath
The needle of a syringe, wire guide, biopsy needle, Huber needle and the like is drawn into a protective cap and sheath arrangement after use for disposal purposes. The cap is tethered to a housing in which the needle is mounted by the sheath. The sheath is made of a film material that has a high tensile strength and a low percent of elongation, such as polyester. The sheath is initially mounted about the needle in a collapsed accordion-like condition between the cap and housing. When the cap is moved along the needle, the sheath is played out over the needle. The cap houses a spring clip to snap over the bore through which the needle is retracted to prevent re-emergence of the needle. The flexible nature of the sheath allows the sheath to pass about the two legs of the Huber needle.
US08066677B2 Rapid exchange catheter with tear resistant guidewire shaft
A rapid exchange-type catheter for aspiration of embolic debris from a blood vessel includes an elongate aspiration tube and a relatively short guidewire tube mounted beside a distalmost portion of the aspiration tube. A proximal portion of the guidewire tube defines a strain relief segment. In one embodiment, the strain relief segment is formed detached from the aspiration tube. In another embodiment, the strain relief segment is minimally attached to the aspiration tube and becomes detached from the aspiration tube when a sufficient transverse force is applied to urge the guidewire tube away from the aspiration tube.
US08066675B2 One piece low drag septum
A one-piece low drag septum is provided for preventing escape of fluid from an introducer needle during removal of such a needle from a catheter and introducer needle assembly. The septum generally includes a distal portion, a proximal portion, a cavity portion, and a longitudinal axis. The distal portion acts as a primary seal to prevent escape of blood from the catheter into the assembly and is generally positioned furthest away from the user of the apparatus and nearest the patient. The cavity portion reduces friction placed on the introducer needle. The proximal portion of the septum acts as a secondary seal to prevent escape of material from the cavity, seals the cavity, and wipes the needle as it is being withdrawn from the catheter assembly.
US08066674B2 Catheter introducer system
A catheter introducer system is provided with a catheter sheath having a valve providing for a friction fit around a catheter. The friction fit is selectively adjustable to vary between a first configuration for longitudinal movement of the catheter through the valve and a second configuration for holding the catheter longitudinally in place. The valve may include a chuck to grip the catheter radially. The chuck may include an annular base and an opposed annular clamp, and a washer disposed between the base and the clamp. At least one of the base and the clamp may include a beveled surface that forces the washer radially inwardly as the base and the clamp are drawn together. The system also includes one or more dilators layered within the sheath. One or more of the dilators may include a preformed arcuate portion configured to access a targeted branched vessel. The layered dilators and sheaths are typically softer and more hydrophilic proceeding from the innermost dilator out to the sheath. The dilator may be reinforced by a wire embedded in the body of the dilator. The distal tip of the sheath may be stiffened by a ring affixed adjacent the distal end. The sheath may include in the innermost dilator a trocar formed of a flexible, hollow outer wire and an inner stiff needle, which can extend beyond the wire for piercing and be withdrawn to relax the wire for advancement of the dilator.
US08066668B2 Passive reuse prevention syringe that uses a flange lock
A syringe assembly includes a syringe barrel having an inside surface defining a chamber, an open proximal end, a distal end, and an outlet; a plunger assembly disposed at least partially within the syringe barrel, including an elongate plunger rod having a locking flange formed thereon; and a plunger head having a distal sealing surface, the plunger rod being engageable with the plunger head such that the plunger rod is adapted to move the plunger head within the chamber of the syringe barrel through an injection cycle; and a flange lock disposed at the open proximal end of the barrel. The flange lock is integral with the open proximal end of the syringe barrel. During the injection cycle, the flange lock engages the locking flange of the plunger rod so as to prevent removal of the plunger rod from the syringe barrel.
US08066663B2 Slide valves equipped in a syringe and thus equipped syringe
There are provided an intermediate slide valve as well as a plunger slide valve equipped in a syringe in direct contact with injection liquids and a syringe equipped with such slide valves, the injection liquids nor valves being not affected with each other.The intermediate slide valve 10 equipped in the syringe 10 comprises an approximately cylindrical first elastic body 13 and an approximately cylindrical second elastic body 14 which is jointed with one bottom surface 13c of the first elastic body 13, the other bottom surface 13a of the first elastic body 13 and a side surface portion continued therefrom being laminated with a synthetic resin film 15 and the other bottom surface 14a of the second elastic body 14 and a side surface portion continued therefrom be laminated with a synthetic resin film 16.
US08066661B2 Viscous formulations and their use in needle-free injection
Formulations are described that are viscous and will benefit from needle-free delivery at high driving pressures. Conventional delivery of these viscous formulations by hypodermic syringes is inconvenient as well as painful. Formulations include those which have a viscosity of about 5 cS or more at about 20° C. and which can have 0.5 ml or more administered by a needle-free injector in about 0.1 second±0.02 seconds.
US08066654B2 Adjustable extension compression posterior spinal orthosis and method
A spinal orthosis and method of applying extension and compression forces onto a user spine includes a lumbo-sacral compression unit conforming to a portion of a user's torso and exerting an encircling compressive force to provide a hydraulic lift. A posterior spinal frame member is secured by the lumbo-sacral compression unit to be cantilevered upward along the user's spine. A pair of adjustable shoulder strap assemblies are connected to an upper portion of the posterior spinal frame member and adjacent a lower portion of the posterior spinal frame member to enable a user to adjustably apply a thoracic force with adjustable controlled buckles and straps positioned on the user's chest.
US08066653B2 Scoliosis brace having angle adjustment unit
Disclosed is a scoliosis brace having an angle adjustment unit and a plurality of support units connected to one another so that the relative position can be changed to support different parts of a human body. The body is pressurized according to the relative position of respective support units so that the spinal column is corrected precisely.
US08066650B2 Strain monitoring system and apparatus
A system for monitoring strain as an indicator of biological conditions, such as spinal fusion, glucose levels, spinal loading, and heart rate. The system includes an inter-digitated capacitor sensor, and RF transmitter, and an associated antenna, all of which are microminiature or microscopic in size and can be implanted in a biological host such as a human or animal. An inductively coupled power supply is also employed to avoid the need for implantation of chemical batteries. Power is provided to the sensor and transmitter, and data is transmitted from the sensor, when an external receiving device, such as a handheld RF ID type receiver, is placed proximate the location of the implanted sensor, transmitter and inductively coupled power supply. The implanted sensor, transmitter and inductively coupled power supply can be left in place permanently or removed when desired.
US08066646B2 Large diameter plethysmograph
A plethysmograph is described that includes a reference chamber having a top wall, a bottom wall, a barrier wall spaced beneath the bottom wall, a continuous side wall having a lower edge, and a first continuous flange with a lower edge below the bottom wall and above the barrier wall; a test chamber having a bottom wall, a continuous side wall with an upper edge, and a second continuous flange extending upwardly from the upper edge, the interior face of one of the flanges including an annular groove with an O-ring in the groove, and the interior face of the other flange being tapered from vertical by up to about 1°; and a manifold having airflow openings in communication with the reference and test chamber and a common exterior airflow opening through a passageway, and a sampling port in communication with the passageway.
US08066639B2 Glucose measuring device for use in personal area network
A glucose measuring system includes a glucose meter that incorporates wireless communication capabilities. The meter can advantageously be a low cost meter by eliminating expensive components, such as the display. The user nevertheless is able to retrieve and view his or her glucose values by referring to displays within the glucose measuring local area network. Feedback via these displays can advantageously be used by the diabetic to create a higher level of confidence and safety.
US08066637B2 Method and apparatus for facilitating physiological coherence and autonomic balance
Method and apparatus for determining the state of entrainment between biological systems which exhibit oscillatory behavior such as heart rhythms, respiration, blood pressure waves and low frequency brain waves based on a determination of heart rate variability (HRV) and an evaluation of the power spectrum thereof. Entrainment reflects a harmonious balance between the two branches of the autonomic nervous system within the body. This internal state of heightened physiological efficiency enhances health and promotes optimal performance. According to one embodiment a method is used to determine the entrainment level based on an entrainment parameter related to HRV. The method first determines the power distribution spectrum (PSD) and then calculates an entrainment parameter (EP), which is a measure of the power distribution in the HRV spectrum. High EP values occur when this power is concentrated within a relatively narrow range of frequencies, and lower values when the power is distributed over a broader range of frequencies. In one embodiment, an apparatus is provided for monitoring the heart beat and presenting this information via a personal computer, handheld device, or other processing means.
US08066632B2 Teleoperated endoscopic capsule equipped with active locomotion system
A teleoperated endoscopic capsule for diagnostic and therapeutic purposes inside an animal body cavity, comprising a body (1) with a plurality of locomotion modules (5) placed on its surface, suitable for moving said body in the body cavity. The capsule also comprises an energy source inside said body and a microcontroller in the body (1) for actuating the locomotion modules (5) on the basis of commands teletransmitted by an operator. A video camera is then provided for capturing images controlled by said microcontroller and a transceiver system for receiving the commands teletransmitted by the operator and for transmitting the images gained through the video camera.
US08066631B2 Flexible endoscope with longitudinal axial channels
The invention relates to an endoscope having a bendable guide element, by means of which a tool can be securely guided and simultaneously steered outward into a broad operating area at the head of the endoscope.
US08066629B2 Apparatus for adjustment and sensing of gastric band pressure
An apparatus is operable to communicate fluid. An exemplary apparatus comprises a housing and a fluid reservoir within the housing. An actuator is operationally engaged with the fluid reservoir. The actuator is operable to effect communication of fluid from or into the fluid reservoir. A sensor is in fluid communication with the fluid reservoir. The sensor is operable to sense a physical parameter of fluid that is in communication with the fluid reservoir as the fluid is communicated from or into the fluid reservoir. An indicator is in communication with the sensor. The indicator is operable to display the physical parameter sensed by the sensor. The apparatus may be used to inject fluid into or withdraw fluid from an implanted gastric band system or for a variety of other uses. Fluid pressure may be adjusted and sensed, and resulting data may be displayed, by a single, integrated instrument.
US08066627B2 Delivery system and method for interstitial radiation therapy using strands constructed with extruded strand housings
A delivery system and method for interstitial radiation therapy comprising substantially axially stiff and longitudinally flexible elongated members made of material which is bioabsorbable in living tissue and a plurality of radioactive seeds dispersed in a predetermined array within the elongate member. The radioactive seeds can be dispersed within assembled half-shells made of the same material. The housing for the radiation seeds can also be manufactured from extruded material. A system for manufacturing the interstitial radiation therapy seed strands that automatically makes the seed strands at the patient's bedside. The delivery system and method further customize the member based on a prescription.
US08066625B2 Exercise aid
An exercise aid useful in allowing human subjects with amputations or other infirmities to use standard exercise equipment is described. In one embodiment, the exercise aid has a harness that securely encircles a shoulder of the subject and has a transverse wing that extends towards the other shoulder of the subject. The exercise aid has a sleeve, preferably adjustable, that fits securely around the upper arm and other shoulder of the subject and has an extension directed toward the transverse wing of the harness. The harness and sleeve may be detachably connected by a fastener. Exercise facilitating features, such as rings, are integrated into the sleeve of the exercise device for attachment to standard exercise equipment thus allowing human subjects with amputations or other infirmities the ability to engage in a full range of exercise options in order to prevent, or reverse, muscular atrophy associated with amputation.
US08066620B2 Method of clutch actuation for hybrid transmissions
A method of actuating a clutch includes commanding a shift, monitoring slip speed, beginning synchronization, filling to a pre-fill volume, and holding at the pre-fill volume. After slip speed reaches a trigger point, the clutch is filled to a first predicted touch point volume, which is greater than the pre-fill volume. The pre-fill volume is approximately 80 to 90 percent of the first predicted touch point volume. The method may determine slip speed derivative, and set the trigger point based thereupon. The method may monitor actual touch point volume and calculate a flow model, which is used to determine when the pre-fill volume has been reached. Filling the clutch to the pre-fill volume may begin simultaneously with commanding the shift. Pressure is generated by an auxiliary pump, which receives power from sources other than an internal combustion engine.
US08066608B2 Automatic transmission
An automatic transmission includes a case; a speed change mechanism; a torque converter having a lock-up clutch axially arranged and freely slidably toward and away from the input shaft; a thrust bearing interposed between the flange unit and the side face of the sleeve unit on the input shaft side; a ball bearing that includes an outer race, a side face of which contacts the first step portion toward the input shaft side, and a propeller shaft connecting member capable of connecting with a propeller shaft, spline-engaging with the outer periphery of the output shaft, and contacting a side face of an inner race of the ball bearing upon being pressed axially toward the input shaft side by the propeller shaft.
US08066602B2 Tension-reducing random sprocket
A sprocket is provided having a plurality of teeth around its circumference. Adjacent teeth are separated by roots each having a root radius defined as the distance between the center of the sprocket and a point along the root closest to the sprocket center in a radial direction. In one aspect of the invention, the sprocket comprises at least two different root radii arranged in a pattern effective to redistribute tensions imparted to a chain by the sprocket at one or more predetermined sprocket orders.
US08066595B2 Hydraulic control system for vehicular power transmitting mechanism
A hydraulic control system for a vehicular drive system including a hydraulically operated belt-and-pulley type continuously variable transmission and a hydraulically operated frictional coupling device engaged for running of a vehicle, the hydraulic control system including: a first solenoid valve for regulating a belt-tensioning hydraulic pressure for tensioning a belt of the transmission, a second solenoid valve for regulating a transient coupling hydraulic pressure to be applied to the frictional coupling device in the process of an engaging action, a line-pressure regulating valve for regulating a line pressure used for hydraulically operated devices of the mechanism, and a hydraulic-circuit switching device operable to apply a control pressure of the second solenoid-operated valve to the line-pressure regulating valve after the frictional coupling device has been placed in a fully engaged state, and to apply a first control pressure of the first solenoid-operated valve to the line-pressure regulating valve while the frictional coupling device is in the process of the engaging action.
US08066589B2 Batting practice tee
An improved multi-adjustable batting practice tee featuring a base assembly with an improved tube assembly thereby enhancing tube movement and overall batting tee stability is disclosed. The base assembly is configured to have standard dimensions for a “HOME PLATE” in accordance with the rules of Major League baseball. The base assembly includes a continuous channel positioned across the entire horizontal plane of the base assembly that includes an inner-locking guide rail system for enhanced batting tee stability.
US08066588B2 High performance golf ball having a reduced-distance
A golf ball including a core and a cover layer, wherein the golf ball has a weight of about 1.39 oz to about 1.62 oz, and at a Reynolds number of about 207,000 and a non-dimensional spin ratio of about 0.095, the golf ball has a lift-to-weight ratio of greater than about 1.7 and a drag-to-weight ratio of greater than about 2.7.
US08066586B2 Grooves of golf club heads and methods to manufacture grooves of golf club heads
Embodiments of grooves of golf club heads and methods to manufacture grooves of golf club heads are generally described herein. Other embodiments may be described and claimed.
US08066583B2 Golf club shaft with high balance point and golf club including same
A golf club shaft having a weight distribution such that the balance point percentage is less than or equal to 44.50%. The weight distribution of the shaft allows for an increase in length and/or club head weight of a golf club while having a reduced impact on the swing weight.
US08066582B1 System and device for golf putting practice
A system and device for golf putting practice, in which the device includes a first leg, a slider element attached to the first leg for grasping a shaft, and a shorter second leg pivotable to the first leg. The second leg is released and squeezed against the first to expose an opening in the slider element to receive the shaft therein, the second leg then released to pivot outward, causing the slider element to move down relative to the upper end of the first leg, closing down on the opening and seating the shaft. A second support device is installed in spaced relation on the shaft to achieve the level horizontal position of the shaft as a guide for a golfer practicing putting strokes with a golf putter.
US08066572B1 System for transmitting real-time game information for a game to a remote device
One or more systems for transmitting real-time game information for a game to a remote device are provided. The system can include at least one remote terminal unit adapted to be communicated with a controller associated with a game information display device. The remote terminal unit can communicate with a network in communication with each remote terminal unit and with a game server. The game server can include a game server processor. The game server processor can be in communication with each remote terminal unit. A game server data storage can be in communication with the game server processor.
US08066569B2 Mirror/display assembly
An integrated mirror/display assembly includes a flip down display integrated with a rearview mirror. The mirror may be mounted to the display and the mirror/display is movable on a pivot between a retracted non-viewing position during normal vehicle operation and an extended viewing position when the vehicle is not in an operating mode.
US08066568B2 System and method for providing feedback on game players and enhancing social matchmaking
A service that receives feedback from players in a game playing service. The service provides an aggregation of the feedback so that a reputation score can be determined by various players in the system. The service takes into account direct feedback from other players about positive and negative experiences with a particular player and expectations about appropriate conduct and type of game being played before a player joins the game session.
US08066567B2 Joystick with control dampening and detent using electrorheologic cylinder
A control system including MR or ER fluid is used to control actuation. The control system is configured to engage or disengage operably coupled elements. A joystick control system for a vehicle includes a controller configured to control engagement of operably coupled elements.
US08066564B2 Gaming system and method having wager allocation
A gaming system which displays a plurality of reels. Each reel is associated with a display area which displays a symbol. A wager is allocated to each one of the display areas. An award is determined based, at least in part, on such allocation.
US08066563B1 Method for enhancing winning outcomes in a reel spinning game
Various embodiments are directed to a reel spinning game having one or more shared award-modifier reels that enhance any winning outcome in a reel spinning game.
US08066558B2 Demand control ventilation sensor failure
Demand ventilation protocols can address the issue of sensor failure while still providing desirable levels of energy conservation. An occupancy indicator such as a sensor can be monitored. If the sensor reading is determined to be incorrect, unexpected or otherwise erroneous, the ventilation system can provide an amount of fresh air sufficient for adequate ventilation without over-ventilating the building.
US08066557B2 Game field dressing tool
The game field dressing tool provides a one-piece tool utilized to dress both small and large game in the field. The tool is fabricated from a suitable rugged metal, such as stainless steel. The tool comprises an elongate handle and a head. The head incorporates a plurality of surface areas adapted to perform different field dressing tasks. A threaded hole is provided in the handle to permit the tool to be converted to a hatchet.
US08066553B2 Wafer clamping device for a double side grinder
A hydrostatic pad for use in holding a semiconductor wafer during grinding of the wafer by grinding wheels. The pad includes hydrostatic pockets formed in a face of the body directly opposed to the wafer. The pockets are adapted for receiving fluid through the body and into the pockets to provide a barrier between the body face and the workpiece while still applying pressure to hold the workpiece during grinding. The hydrostatic pads allow the wafer to rotate relative to the pads about their common axis. The pockets are oriented to reduce hydrostatic bending moments that are produced in the wafer when the grinding wheels shift or tilt relative to the hydrostatic pads, helping prevent nanotopology degradation of surfaces of the wafer commonly caused by shift and tilt of the grinding wheels.
US08066547B1 Bridge row tool
A lapping row tool comprising a plurality of bending nodes having a space between adjacent ones of said nodes and each of which has an end surface to manipulate a row of magnetic heads during lapping. A bridge extends along the end surfaces of the bending nodes and across the space between the adjacent bending nodes. The bridge provides a surface for holding the row of magnetic heads that prevents the flexing of the row into the space between the bending nodes during lapping while allowing the bending nodes to manipulate the row during lapping.
US08066546B2 Brassiere
A brassiere is provided with a front piece forming the breast cups and with two side pieces extending around the upper body of an individual, the first ends of which are fastened to the front piece and the second ends of which can be connected in the back area of the wearer. Each side pieces has a support piece forming an outline of the side pieces with an upper edge and a lower edge. On the outside of the side pieces an outer textile blank is provided, which is connected with the supporting element in the area of the upper edge and the lower edge. The outer textile blank is folded over twice with its edge, over the upper edge and the lower edge, wherein the first fold, travels directly along the upper or lower edge and the second fold travels between the support piece and the first fold.
US08066545B2 Toy vehicle track play set
A vehicle track play set includes a base, a plate coupled to and extending upwardly from the base, and first and second tracks extending along the plate toward the base. The first track includes a first curved portion extending outwardly from a first surface of the plate and a second curved portion extending outwardly from an opposite second surface of the plate. The first track extends through a first opening in the plate between the first and second curved portions. The second track includes a third curved portion extending outwardly from the second surface and a fourth curved portion extending outwardly from the first surface. The second track extends through a second opening in the plate between the third and fourth curved portions.
US08066540B2 Collapsible flotation device having back support
A collapsible flotation device is provided that uses a coilable spring coupled to a panel to collapse the device when the spring is coiled, and to expand the device when the spring is uncoiled configuration. The spring can be contained within a sleeve along the outer portion of the panel. A support member that traverses the panel is provided. An inflatable bladder disposed about a part of the outer portion of the panel and coupled to the support member buoyantly supports a body weight of a user. The combination of the inflatable bladder and the support member provide support for a user in a seated position on the panel. Many configurations are disclosed, including a multi-user collapsible flotation device, multiple connected single-user flotation devices, and so forth. A back support member and a headrest, both of which can be inflatable, provide additional support for a user to maintain a seated position on the panel. A foot support member is provided for the comfort of the user.
US08066539B2 Marine propulsion system
A marine propulsion system includes a transmission mechanism arranged to transmit a driving force generated by an engine to propellers with a speed thereof changed to a low speed reduction ratio and a high speed reduction ratio; a control lever section operated by a user in controlling drive of the engine; and a control portion and an ECU controlling a shift between reduction ratios of the transmission mechanism based on operation of the control lever section by the user. The control portion and the ECU control a shift between reduction ratios of the transmission mechanism based on a transmission control map providing a reference for a shift between reduction ratios of the transmission mechanism taking into consideration an engine speed of the engine and a lever opening of the control lever section. This arrangement provides a marine propulsion system in which both acceleration performance and maximum speed can approach levels that a user desires.
US08066536B2 Spring connector
A spring connector includes a barrel, a plunger and a spring. The barrel includes a longitudinal space formed therein, an opening formed at a top thereof, a bottom plate formed at a bottom thereof and a narrow portion formed from a middle portion and to the bottom thereof. The plunger includes a contact portion protruding from the opening, a sliding portion received in the longitudinal space, and a limit recess formed in the lower sliding portion. A top end of the spring is received in and limited by the limit recess, and a bottom end and a middle portion is limited by the narrower portion to restrict the spring being compressed along a longitudinal direction thereof. The spring is also prevented from deviating from the longitudinal direction thereof.
US08066530B2 Portable assembly having a subscriber identification module
The assembly has a subscriber identification module comprising a housing with a recess disposed in the housing. An electrical connector portion is secured to the housing. The connector portion comprises a dielectric body and connector terminals. A subscriber identification module is housed in the housing, where the subscriber identification module has device terminals. A conductor or flexible substrate electrically connects the connector terminals to the device terminals. A protective filler overlies the subscriber identification module and at least part of the conductor or the flexible substrate.
US08066528B1 Card connector
A card connector includes an insulating housing which defines a first inserting groove and two soldering openings opened behind the first inserting groove with top ends thereof communicating with the first inserting groove. A plurality of first signal terminals is disposed in the base portion and each has a contacting portion exposed in the first inserting groove and a soldering tail projecting in the soldering opening. A main shell enclosing the insulating housing has a base plate covered on the first inserting groove, and a monitoring gap opened in a rear of the base plate and facing the soldering openings. An auxiliary shell, enclosing the soldering openings after the soldering tails are soldered to a printed circuit board, has a top shielding plate mated with the monitoring gap to cover tops of the soldering openings, and a rear shielding plate covering rears of the soldering openings.
US08066526B2 Jumper connector
A method and apparatus for jumping a pin connections in an electrical device are provided. The electrical device can be a vehicle having a data link connector that once mated with the apparatus, such a jumping connector that will jump at least two pin connections in the data link connector. The jumping connector can also have dip switches that be in the active or inactive state. In the active state, the dip switch will cause a connection to one of the pin connectors on the electrical device while the inactive state, the dip switch will not cause a connection to one of the pin connectors on the electrical device.
US08066514B2 Automated processing of training data
Embodiments of a method and system for developing a training program for a trainee are provided. In one embodiment, in a training system, the method may include profiling the trainee by processing at least one of physiological data, psychological data and training program data associated with the trainee; designing a training program for the trainee in accordance with the profile of the trainee; receiving training activity data communicated in association with the trainee performing at least one training activity; and, automatically modifying at least a portion of the training program in the training system in accordance with at least the communicated training activity data.
US08066511B2 Asymmetrical dental implant
A dental implant is provided for supporting a dental prosthesis. The implant can include a body having an outer surface, an apical end, and a coronal portion. The dental implant can include at least one thread located on at least a portion of the outer surface of the body. The dental implant can include a collar having a top surface that defines two peaks and two valleys, where the one valley is more coronal than the second valley.
US08066510B2 Dental agent applicator
A dental agent applicator has a barrel, a sealing plug, a delivery head and a plunger. The barrel has a proximal end, a distal end and a chamber defined through the barrel. The sealing plug is mounted in the chamber and hermetically obstructs the chamber. The delivery head is movably mounted on the distal end of the barrel and has a hub and a nozzle tip. The hub is mounted movably in the distal end and selectively moves the sealing plug to make the chamber communicate with the delivery head. The nozzle tip is mounted on the hub. The plunger is mounted slidably in the proximal end of the barrel. The delivery head is mounted permanently on the barrel. Using the dental agent applicator without having to replace any sealing cap with the delivery head is simple and convenient.
US08066507B2 Horizontal injection molding machine
A rotary plate is rotatably supported with respect to a stationary base using an R-guide, and the weight of the rotary plate and a mold mounted to the rotary plate is also supported by the R-guide in addition to a bearing. Therefore, a moment and a vertical downward load acting on the bearing of the rotary plate can be reduced. A block of the R-guide is fixed with respect to the rotary plate side through a disc spring. Therefore, while the rotary plate is rotating, the elastic force of the disc spring causes the rotary plate to separate from the stationary base by a space, which reduces the rotational resistance of the rotary plate. During mold clamping, respective pressure-receiving surfaces of the rotary plate and the stationary base contact each other against the elastic force of the disc spring, which enables reliable transfer of a mold clamping load to the stationary base.
US08066496B2 Reciprocated pump system for use in oil wells
A reciprocated pump positioned at the lower end of a string of tubing in a bore hole that provides a passageway for moving formation fluid to the earth's surface, including a pump barrel supported in communication with the tubing and a standing valve at the lower end thereof providing a first passageway through which formation fluid flows into the pump barrel, the pump barrel having an intermediate vent port providing a second entry passageway, and a tubular plunger reciprocated within the barrel and having an upper and a lower portion with a plurality of non-metallic seal rings separated by metallic spacers received on the plunger upper portion and configured to support a column of formation fluid within the tubing to substantially isolate the portion of the barrel below the non-metallic seal rings from the tubing pressure to thereby allow formation fluid to move into the pump barrel.
US08066492B2 Drive device for the oil pump of a motor vehicle transmission
A drive device (2) for the oil pump (6) of a motor vehicle automatic transmission, in which the oil pump (6) on the one hand can be coupled to the drive motor by way of an overrunning clutch (34) and on the other hand is drivingly connected to an auxiliary electric motor (22), which is powered by the on-board power supply of the motor vehicle. The electric motor (22) is arranged outside of the pump housing (8) and is drivingly connected to a driven pump impeller wheel (ring gear 10) that is arranged in the pump housing via a non-rotatable connection.
US08066488B2 Highly slenderness rotor
The present invention relates to a rotor for gas or steam turbines having a disk (1), an outer cover (2) and a plurality of blades (3). The disk (1) defines the portion of less diameter of the rotor and has an inner surface configured to be coupled on a shaft (100) of the turbine or connected to an axially adjacent disk (1′, 1″); an outer surface configured for housing a plurality of blades (3). The outer cover (2) defines the portion of greater diameter of the rotor. The blades (3) have a root (31) configured to be coupled on the disk (1) and a tip (32) opposite to the outer cover (2). Between these blades there is a plurality of blades (3) welded together at the tip (32) to form groups of blades (3a) and individual blades (3b) intercalated between groups of blades (3a).
US08066487B2 Fan shaft seat structure
A fan shaft seat structure including a shaft bushing and a heat dissipation member. The shaft bushing has an open end, a closed end and a, connection section. A receiving space is defined between the open end and the closed end. The connection section extends from the closed end in a direction reverse to the receiving space. The heat dissipation member has a first face and a second face. The first face is flush with a first end of the connection section in contact with the closed end of the shaft bushing. The second face is flush with a second end of the connection section. The shaft bushing is integrally connected with the heat dissipation member to increase heat dissipation area and save working time and manufacturing cost as well as achieve better heat dissipation effect.
US08066486B2 Method and apparatus for vibration-based automatic condition monitoring of a wind turbine
Method and apparatus for vibration-based automatic condition monitoring of a wind turbine, comprising the steps of: determining a set of vibration measurement values of the wind turbine; calculating a frequency spectrum of the set of vibration measurement values; calculating a cepstrum of the frequency spectrum; selecting at least one quefrency in the cepstrum, and detecting an alarm condition based upon an amplitude of the cepstrum at the selected quefrency, and a wind turbine therefor.
US08066484B1 Film cooling hole for a turbine airfoil
A film cooling hole for a turbine airfoil. the first embodiment is a film cooling hole aligned with the stream-wise direction of the hot gas flow over the hole and includes a metering section followed by a diffuser section. The diffuser section includes a left side wall and a right side wall both having a curvature facing outward and at about the same radius of curvature. The diffuser section also includes a top side wall and a bottom side wall which both have a curvature in the stream-wise direction, and in which the radius of curvature of the top side wall is greater than the radius of curvature of the bottom side wall. A second embodiment is a film cooling hole offset from the stream-wise direction of flow and includes the four walls with a curvature, but in which the left side wall has a greater radius of curvature than the right side wall due to the stream-wise offset of the hole.
US08066482B2 Shaped cooling holes for reduced stress
A gas turbine engine component having shaped cooling holes that further enhances the cooling of a desired region while reducing stress levels in and around the cooling holes is disclosed. The cooling holes are generally elliptically-shaped and diffuse from a cooling fluid supply side to a discharge side and are oriented on the turbine component to reduce stress concentrations while directing the cooling fluid to a desired surface or location. The elliptical cooling holes have openings in the surface that have high points that are concentric and planar.
US08066477B2 Staged centrifugal pump apparatus for pumping a viscous fluid
A pump apparatus comprising a series of stacked impellers rotating about a common axis, for pumping a viscous fluid mixture upwardly from an underground location. The pump apparatus comprises a generally cylindrical housing having an intake at or near its suction end. A plurality of impellers are mounted in the housing to rotate about a shaft, which each induce flow of the mixture toward the discharge end of the pump. Each impeller has a series of radially outwardly extending vanes, one or more of such vanes having a radially-extending horizontal slot and arranged to generate an upwardly moving column of fluid. Without being limited to the theory of operation, the horizontal slot in the vanes assists in creating laminar flow and reducing turbulent flow.
US08066475B2 Labyrinth compression seal and turbine incorporating the same
A uniquely configured rotating seal tooth is used in conjunction with commonly used labyrinth-type seals that provide a seal between a rotating component and a stationary component. The uniquely configured rotating seal tooth produces a compression mechanism to counter leakage flow through the labyrinth of seal teeth, thereby lessening the pressure gradient that drives leakage and reversing the direction of some of the leakage flow.
US08066471B2 Annular flow duct for a turbomachine through which a main flow can flow in the axial direction
Disclosed is an annular flow duct for a turbomachine, the flow duct arranged concentrically about a machine axis running in the axial direction and defined by a boundary wall of circular cross section for directing a main flow, wherein the boundary wall has a plurality of return flow passages distributed over its circumference and through which in each case a partial flow is detached from the main flow at a bleed position and returned to the main flow at a feed position situated upstream of the bleed position, and having aerofoils, arranged radically in the flow duct, of a blade ring, the aerofoil tips of which lie opposite the boundary wall, with a gap formed in each case, wherein the aerofoils are movable in a predetermined rotation direction along the circumference of the boundary wall. Furthermore, a compressor which is insensitive to pumping and flow separations, as viewed in rotation direction, the bleed position of each return flow passage lies upstream of the corresponding feed position.
US08066455B2 Connection system for two tool parts
A connection system which produces an aligned connection between first and second tool parts includes a spigot projecting from the first tool part, and a spigot-receiving recess formed in the second tool part. The spigot and the recess have correspondingly shaped, non-circular cross-sections. The spigot is not oversized relative to the recess, and may be smaller than the recess, so that the spigot can be inserted into the recess without the recess being expanded or the recess being compressed.
US08066449B2 Method for dry isolation of a water passage of a dam
A needle-beam cofferdam, needles and associated method for dry isolation of a water passage of a dam, the method comprising providing a support beam which spans between piers of the water passage, providing at least one hollow metal needle having a major axis, and positioning the hollow needle with the major axis substantially vertically oriented, the hollow needle engaging with a sill of the dam and engaging with the support beam. A plurality of vertically positioned needles may thereby isolate the water passage. The method also includes positioning of hollow needles with the major axis in a substantially horizontal orientation.
US08066448B2 Dust suppression agent
A composition for dust suppression including an acrylic polymer, a polyvinyl acetate polymer, glycerin, and water is herein disclosed.
US08066447B2 Wood mat and apparatus and method for assembling same
A wood mat has a first layer of timbers extending parallel to one another in a longitudinal direction and a second layer timbers spanning across the first timbers parallel to one another and transversely to the first timbers such that each second timber intersects a plurality of the first timbers at respective intersecting locations of the mat; and a plurality of pressed fasteners mounted at selected intersecting locations through drilled holes formed by either a rivet fastener or a press fit fastener having opposed ends compressively joining the timbers therebetween.
US08066445B2 Apparatus for adjusting length of tension tie for cable network antenna
An apparatus for adjusting the length of a tension tie mounted on a deployable antenna based on a cable network structure includes a cable retainer provided with a retaining hole, a cable being connected to the cable retainer; a retaining case coupled to the outer periphery of the cable retainer and provided with a plurality of retaining holes; and a retainer positioned inside the cable retainer and configured to extend through the retaining hole of the cable retainer and through one of the retaining holes of the retaining case so that the cable retainer and the retaining case are prevented from moving in the longitudinal direction.
US08066444B2 Disposable wipe with substance-filled blisters
A device including a base layer; a wipe layer attached to the base layer to define an interior space between the wipe and base layers; a plurality of blisters positioned within the interior space, each blister having a blister volume, wherein the sum of the blister volumes is a total blister volume; and an indication disposed on the wipe layer or the base layer corresponding to a single blister or a group of blisters indicating the ratio of the blister volume of that single blister or the sum of the blister volumes of that group of blisters to the total blister volume is disclosed.
US08066441B2 Adjustable connecting mechanism for camera device
An adjustable connecting mechanism for a camera device includes a frame, a tubular fixing member and a locking screw The frame forms a mounting portion; the mounting portion defines a through hole. The fixing member defines a first engaging portion and a second engaging portion spaced a predetermined distance from the first engaging portion along an axis of the fixing member. The locking screw is able to pass through the through hole and selectively engage in the first engaging portion or the second engaging portion, to adjust a height of the fixing member relative to the frame.
US08066436B2 Male contact for optical fiber
The invention relates to a male contact for an optical fiber (1), that comprises an outer body (2) of an elastically deformable material, a cylindrical guide (6) having a front portion (5) attached in the rear portion (4) of the outer body (2) and a rear portion (7) protruding from the rear portion (4) of the outer body (2). A cable adapter (65) extends through the cylindrical guide (6). An elongated floating ferrule (18) extends through the front portion (3) of the outer body (2). The ferrule (18) is connected to a ferrule holder (13) movably mounted in said outer body (2). It comprises abutment means (19) bearing on the first shoulders (11) of the outer body (2), and a helical spring (21) provided between the front portion (5) of the cylindrical guide (6) and the abutment means (19) of the ferrule holder (13). The cable adapter (65) is mounted so as to float within the cylindrical guide (6).
US08066431B2 Cable temperature monitor
An apparatus that allows for the testing of multiple wraps of cable in environments of varying temperature, pressure, and in different fluids in a single apparatus, and can be tested against the varying loads the cable may encounter is disclosed. In the illustrative embodiment of the present invention, the multiple wraps of cable are simulated by layering electrically-insulated portions of the cable on top of one another inside an environmentally controlled container. This container has two parts: a thermally-insulated container and a pressure container.
US08066427B2 Stirring and mixing apparatus
A cooking apparatus includes a spatula assembly and a cooking container comprising an upper access opening and an inner, cooking surface having a spherical surface portion. The spatula assembly includes a spatula driver and a curved spatula pivotally mounted to the cooking container for moving along the cooking surface and about a pivot axis between first and second positions. The pivot axis passes through the center point of the spherical surface portion. The spatula assembly may be constructed so that at least one of the first and second positions is above the pivot axis. The curved spatula may also include a spatula body having an outer surface and a barrier member extending radially inwardly from the outer surface, the outer surface contacting the cooking surface of the cooking container.
US08066426B2 Mixing device configured to blend food
A mixing device, configured to blend food, including a housing, having a motor, and a jar removably mounted to the housing for containing food. The housing includes a base, a central body and a pair of side bodies that attach to the sides of the central body in an assembled configuration of the housing. Further, the housing includes a top removably mounted to the base to clamp the side bodies and the central body between the top and the base when the housing is in the assembled configuration.
US08066425B2 Homogenisation valve
The invention relates to an improved homogenisation valve, and more particularly, but not exclusively, to a homogenisation valve for use in homogenising emulsion explosives. The homogenisation device comprises a body having a flow passage therethrough, opposing first and second homogenisation members located in the flow passage; the homogenisation members having opposing homogenisation surfaces that form a flow restriction of the flow passage therebetween. At least one of the homogenisation surfaces has a flow resistance being suitable to cause at least part of the flow passing through the flow restriction to be diverged in a non-linear path across the homogenisation surface.
US08066424B2 Mixing device
The invention relates to a mixing device which is arranged in a flow channel and a mixing method for mixing a fluid flowing through the flow channel in a main direction of flow. The mixing device has a plurality of mixer disks which generate leading edge eddies in a fluid flowing through the flow channel in a main direction of flow. The mixer disks are arranged in mixer disk rows in row axes running essentially across the main direction of flow. The mixer disk rows are arranged side by side in the main direction of flow in a common flow channel section where the mixer disks of neighboring mixer disk rows are alternately angled in a positive angle of attack and in a negative angle of attack with respect to the main direction of flow.According to this process, the fluid flowing through the flow channel is mixed thoroughly by a leading edge eddy system, whereby in the mixing method presented here at least two contra-rotating leading edge eddy systems are generated in a common flow channel section.
US08066423B2 High speed and direct driven rotating equipment for polyolefin manufacturing
An apparatus and method for melting polymer is provided. In at least one embodiment, the apparatus includes a housing, two or more rotatable members at least partially contained within the housing, where each rotatable member having a shaft coupled thereto. The apparatus also includes a motor having a drive shaft directly coupled to the shaft of the rotatable members such that the rotatable members rotate at a speed of the motor drive shaft. The rotatable members are preferably non-intermeshing and counter-rotating.
US08066422B2 Material moisture content adjustment method
When making moisture content adjustment by adding liquid such as water to a raw material such as pulverulent material including bentonite, uniform mixing of the liquid such as water with the raw material is given with relatively simple facilities, moisture content adjustment of a large quantity of raw materials is attainable, and besides, a material having satisfactory performances such as impermeability is obtainable through uniform moisture content adjustment. Within a mixing tank (1) configured with a normal powder mixer kept at low temperatures, pulverulent bentonite (A) and fine granular ice (B) are stirred and mixed. Stirring and mixing of the fellow pulverulent materials are adapted to uniformly mix the pulverulent bentonite (A) and the fine granular ice (B), enabling uniformly moisture content-adjusted bentonite to be obtained. A liquid-nitrogen gas bomb (21), for instance, is connected to the mixing tank (1), causing the inside of the mixing tank to be kept at low temperatures with nitrogen gas supplied from the bomb, before putting the prepared fine granular ice (B) through an inlet port (20).
US08066421B2 Method of adding STMP to a gypsum slurry
The disclosure relates to a method for effectively and efficiently adding sodium trimetaphosphate to a gypsum slurry. In one exemplary embodiment, the sodium trimetaphosphate is added at the same time as foam is added to the gypsum slurry through the foam waterline. In another exemplary embodiment, the sodium trimetaphosphate is added at the same time as additional water is added to the gypsum slurry through the gauging waterline. The sodium trimetaphosphate can be added to either or both waterlines in its dry form or in a diluted solution.
US08066411B1 LED lighting tube with rotational end caps
An LED lighting tube having a first segment, a second segment, and a rotating connector between the segments. Each segment has an elongated cylindrical housing, an aperture in the sidewall of the cylindrical housing, a reflector centered within the aperture, a circuit board within the cylindrical housing, and a rotatable electrical coupling connected to an outer end of the cylindrical housing. The circuit board has an LED that aligns with the aperture. The rotatable electrical coupling has a limiter insert that provides a rotative stop, a collet that at least partially surrounds the limiter insert and is rotatable about the limiter insert, and an interface connector secured to the limiter insert and in electrical communication with the circuit board. The rotatable electrical coupling permits the LED lighting tube to connect to a light fixture while also permitting the cylindrical housing to rotate relative to the light fixture. The rotation of the collet about the limiter insert is limited by the rotative stop.
US08066410B2 Light fixture with multiple LEDs and synthetic jet thermal management system
A light source (101) is provided which comprises (a) a housing element (107); (b) a heat sink (109); (c) a first flow channel element (111) which, alone or in combination with said housing element, creates (i) a first set of flow paths (221) for the flow of fluid in a first direction through the light source, and (ii) a second set of flow paths (223) for the flow of fluid in a second direction through the light source; (d) a set of synthetic jet actuators (143, 145) having at least one member and being in fluidic communication with said first set of flow paths; and (e) a set of LEDs (113) containing at least one member and being in thermal contact with said heat sink.
US08066408B2 Incoupling structure for lighting applications
Light incoupling structures for lighting applications, such as lightguides. The incoupling structures include an optically substantially transparent medium for transporting light emitted by a light source and an optical element including at least one hole in the medium for coupling light together with optional further optical elements. A lighting element includes a light source with related integrated optics.
US08066407B2 Electronic luminaire based on light emitting diodes
An electronic luminaire based on light emitting diodes, for illumination with a low electric power consumption at indoor spaces for offices or wide spaces, which use false soffit systems on their ceilings, in order to adapt their lighting. It is based on a closed module that is manufactured with hot galvanized stamped laminated steel or with injection molding plastic, and comprehends four sections: A), B), C) and D), where A) corresponds to a casing which houses B) and C) overlapped sections, and these are finally assembled to D) section, together with an electronic power source; the B) section is an electrical harness, the C) section is a plurality of LED bars, and D) section corresponds to the reflecting screen, that counts with a plurality of individual reflecting elements of concave, elliptical or parabolic type.
US08066404B2 LED lamp
An LED lamp includes a plurality of LED light units juxtaposed together and a connecting member engaging with the LED light units. Each LED light unit includes a heat sink and an LED module engaged on the heat sink. The heat sink defines a groove group at each lateral portion thereof. The connecting member includes a plurality of inserts received in grooves of the groove groups of the heat sinks of neighboring LED light units and clasping the neighboring LED light units together thereby to secure the LED light units into the LED lamp.