| Document | Document Title |
|---|---|
| US08068063B2 |
Dual-band coupling device comprising first and second annular grooves fed by first and second feed conductors
A coupling device is provided. The coupling device has a substrate, a ground element, a first feed conductor and a second feed conductor. The substrate has a first surface and a second surface. The ground element is disposed on the second surface, wherein the ground element has a first annular groove, a second annular groove and a feed slot, the second annular groove surrounds the first annular groove, the feed slot is connected to the first annular groove and the second annular groove. The first feed conductor is disposed on the first surface corresponding to the first annular groove and the second annular groove, wherein the first feed conductor couples the ground element to feed an electric current. The second feed conductor is disposed on the first surface corresponding to the feed slot, wherein the second feed conductor couples the feed slot to feed a magnetic current. |
| US08068060B2 |
Combination of tube assembly and clip for wireless antenna grounding
An antenna tube configured to accommodate a grounding clip and an antenna, the antenna tube having a cylindrical tube having an upper end and an inner end opposite the upper end; a circumferentially extending groove in the cylindrical tube located between the upper end and the inner end; and a tapered lip at the inner end of the cylindrical tube, wherein the grounding clip fits between the circumferentially extending groove and the tapered lip, and at least a portion of the antenna slidably fits into the upper end of the cylindrical tube. |
| US08068059B2 |
Antenna device, electronic device and antenna cover
An antenna device is mounted in a note PC and is used for communication between the note PC and the external of the note PC. The antenna device is provided with an antenna for wireless LAN for transmitting and receiving radio waves, and a cover. The cover is formed of a dielectric material for covering the antenna with a wall and a ceiling, and strengthens the directivity of radio wave communication on the wall side of the antenna device by a double layer structure of the ceiling that is thicker than the wall. |
| US08068053B1 |
Low-profile lens method and apparatus for mechanical steering of aperture antennas
A low-profile lens element for steering a beam is provided. Specifically, the low-profile lens element is mechanically rotatable such that a beam can be steered in any direction within three-dimensional space. The lens element may include a number of discrete portions for differentially delaying adjacent discrete portions of a beam in order to effect beam steering. These discrete portions may vary in width. In addition, multiple lens elements may be provided. |
| US08068049B2 |
Passive detection apparatus
A passive detection device is disclosed comprising a plurality of antennas, receivers, and a digital beamformer, wherein the antennas and receivers are adapted to receive radiation of millimeter wavelengths from a near field region, to process and digitize it. The beamformer is adapted to process the received information and to generate static image information relating to the region. An indication means is provided to indicate the presence of objects of interest. The beamformer is preferentially adapted to generate information simultaneously in a plurality of planes at different distances from the apparatus. The indication means may comprise an array of pixels along the length of the apparatus to display image information, and may use the multi-planar information to construct images of the region comprising data from a plurality of planes. The invention has utility in security scanning applications such as at airports or other locations where security detection equipment is employed. |
| US08068041B2 |
Handheld electronic device and keypad having tactile features
An improved handheld electronic device and keypad include tactile features that help a user to identify certain keys of the keypad. In the present exemplary embodiment, the keypad includes keys in a predetermined region that can be employed during a telephone operation. The keypad additionally includes other keys outside the predetermined region. The keys in the predetermined region include tactile features that enable the user to identify and actuate the keys in the predetermined region during a telephone operation with the user directing minimal visual attention to the handheld electronic device. |
| US08068039B2 |
Flight track display system using data from a plurality of sources
Described is a system and method for displaying flight track data. The system and method include a data feed arrangement to receive target data points from a first data source and a second data source, a data receiving arrangement correlating target data points from the first data source with corresponding target data points received from the second data source, the correlation being based on location and time information in the target data points, a data analyzing arrangement to analyze the target data points and correlated data points and store each target data point and correlating data point in a target flight record, the target flight record corresponding to a target aircraft, a data generation arrangement to generate a flight track for the target aircraft using the data stored in the target flight record, wherein the flight track includes a first portion generated from the first data source and a second portion generated from the correlated target data points and a data distribution arrangement to organize the flight track into a displayable file and distribute the file to users of the system, wherein the displayable file is displayed on a graphical user interface including the flight track information. |
| US08068037B2 |
Advertisement systems and methods for notification systems
Advertisement systems and methods are provided for use in connection with notification services or systems. One such method, among others that are disclosed, can be practiced by performing at least the following steps: (a) monitoring travel data associated with a mobile thing; (b) contacting a party based upon the travel data; (c) providing an advertisement to the party during the contact; and (d) charging a fee for or otherwise monetarily benefiting from providing the advertisement. |
| US08068033B2 |
Method of detecting contamination in industrial process boiler systems
This invention provides a method for detecting contamination of a boiler condensate and/or a boiler feedwater in industrial fermentation processes. The method includes measuring an oxidation-reduction potential at one or more locations in the fermentation process with one or more devices capable of measuring oxidation-reduction potential at operating temperature and pressure. If the measured oxidation-reduction potential is not within an optimum range, an alarm is triggered. |
| US08068031B2 |
RFID devices and methods for overlapped objects
Readability of overlapping radio frequency identification (RFID) devices on overlapping objects, such as RFID labels on stacked garments, is improved by having different antenna configurations for the overlapped RFID devices. Each pair of closest overlapped RFID devices may have different respective antenna configurations. The different respective antenna configurations may be mirror images of one another, or may have the same shape, with a relative rotation between the two. The different antenna configurations may substantially fill an antenna-receiving portion that is located in the same relative location in each of the RFID devices, with the antenna-receiving portion covering most of an area of the RFID devices. Feedpoints of the different antenna configurations, for receiving a strap or interposer for coupling to the antenna configurations, may be in the same relative location. |
| US08068030B2 |
Deactivatable RFID labels and tags and methods of making same
Disclosed are deactivatable RFID labels and tags in individual and web form, and methods of making same. When it is desired to deactivate the label or tag, the tag or label is subjected to tearing. One arrangement involves providing the label or tag with a tear strip by which the RFID transponder in the label or tag is destroyed, and in another arrangement a tag can be torn along a weakening line to destroy the RFID transponder. |
| US08068029B2 |
Systems and methods for indicating a quality of grouped items
Systems and methods for determining a relative quantity of recyclable items with respect to a total number of items are disclosed. In one embodiment of the present invention, a computer-implemented method includes reading an identifier respectively associated with at least some of a total number of items. The computer determines a number of identifiers associated with the recyclable items. The computer also receives the total number of items, and computes the relative quantity of recyclable items by dividing the number of identifiers associated with the recyclable items by the total number of items. |
| US08068026B1 |
Periodic tester to determine readiness of a fire pump system
A periodic tester to determine the readiness of a fire pump system interfaces with a fire pump controller, an electric motor, and a sprinkler system. The fire pump controller has a power on/off sensor which interfaces with an electric motor which starts the fire pump to provide water to the sprinkler system. The power on/off system has a contactor coil as a component. The periodic tester targets two of the main components of fire system failure: the power on/off sensor and the contactor coil. The periodic tester may be retrofitted to existing systems and interface either directly or indirectly with the power on/off sensor to accommodate both systems that have a solenoid valve and those that do not. The periodic tester is designed to attempt to start the system only once during a set cycle. Any failure to start is displayed through audible and visual alarms. |
| US08068025B2 |
Personal alerting device and method
A personal alerting device and method for detecting an approaching sound source includes a sound detector for detecting environmental sounds and for providing an electrical signal to a sound analyzer. The sound signal is analyzed to determine a baseline sound pattern comprising a plurality of distinct sounds corresponding to sounds emitted from a reference sound source. The distinct sounds in the baseline sound pattern may have substantially the same amplitude and time interval. The sound signal is monitored and compared against the baseline sound pattern to determine whether a target sound pattern is present in the sound signal, the target sound pattern corresponding to sounds emitted by the approaching sound source. When it is determined that the target sound is present in the sound signal, one or more of an audible, visual and tactile alert may be emitted to provide warning of the approaching sound source. |
| US08068024B1 |
Location-based alert processing
In some embodiments, techniques for processing an alert may include receiving a message, wherein the message includes a specification of a first location, creating an alert, associating the specification of the first location with the alert, determining a first current location as a second location, wherein determining the second location follows receiving the specification of the first location and precedes determining a third location, determining that the second location does not match the specification of the first location, determining a second current location as the third location, determining that the third location matches the specification of the first location and presenting information relating to the alert. |
| US08068023B2 |
System for maintaining security of evidence throughout chain of custody
An evidence chain of custody system that is application-specific auditable and trackable secure smart mobile containers (SMC) for securely storing evidence items that are collected at crime scenes and search locations pursuant to subpoenas or warrants. Each SMC includes a electronics package that can read RF tags applied to evidence bags or totes placed in the SMC or for oversized items, associated with the event or scene, that are tagged with active RF tags. The electronics package also includes condition sensors and an RF transmitter module to permit remote reporting and monitoring of GPS/RSSI location and condition. The SMC includes an electronic lock that provides access security and an audit trail of all opening, closing, and other events. |
| US08068021B1 |
Room monitor for critical environment rooms
A room monitor having a second display includes a controller, a first display and a second display. The first display is preferably a touch screen monitor, which allows the entry of data into the controller without the need for a keyboard. However, the controller may be programmed through a keyboard. The controller includes a plurality of inputs and outputs for monitoring and/or controlling such room environmental factors as pressure, temperature, humidity and lighting. The inputs are used to read sensors. The outputs are used to actuate control devices. The first display includes a plurality of menus for controlling at least one environmental factor. The second display shows information the condition of a critical environment room. There is at least one message displayed on the second display. A second embodiment of the room monitor includes a controller and the first display. The first display must be a touch screen monitor. |
| US08068020B2 |
Management of resources in emergency and operational situations
Provided is a method for designing, managing and executing response plans. Specific plan and resources are defined and a defined plan is executed either automatically or manually according to pre-determined or “real-time” parameter definitions. An executed plan notifies, by various user-defined means, actively or pre-defined parties in a near simultaneous fashion of security communications, notifications, directives and/or information. One embodiment of the system includes a component that requires a notified party to acknowledge a particular notification event by responding with a personal identification number (PIN) or calling a specified telephone number and entering the PIN. The system enables parties to be organized into groups based upon member profiles. Individual parties can be assigned to sub-groups, enabling specifically designed communications to go to the parties of any particular sub-group. Alternative means of contact can be prioritized and utilized either simultaneously or sequentially until contact with a particular party is achieved. |
| US08068011B1 |
System and method for interactive user-directed interfacing between handheld devices and RFID media
Systems and methods for interactively interfacing handheld devices and RFID media are described. A method for interactively interfacing HHDs and RFID media. The method includes starting an application on a HHD for interfacing with RFID media, the HHD including a RFID reader, receiving user input relating to the storing of commands or messages of RFID media, creating one or more commands or messages based on the received user input, and storing the one or more commands or messages on a RFID media using the RFID reader. |
| US08068009B2 |
Radio frequency identification system and a method of operating same
A tag receives wireless signpost signals that include timing data, determines time information associated with an event as a function of the timing data, and transmits a wireless tag signal that contains the time information. In a another configuration, a signpost transmits wireless signpost signals having a selected transmission range; a reader proximate to the signpost receives wireless tag signals with a reception range that is approximately the same as the selected transmission range; and a tag movable relative to the signpost and reader responds to receipt of a wireless signpost signal by transmitting a wireless tag signal containing a tag code associated with the tag. |
| US08068008B2 |
Emergency responder credentialing system and method
A system for collecting, verifying, and managing identity data, skill data, qualification data, certification data, and licensure data of emergency responders. The system trusted verification of identity, skills, qualifications, certifications, and licensure, and disseminates information specific or related to identity, skills, qualifications, certifications, and licensure at the scene of an emergency. The system includes information collection devices, data storage media, information retrieval devices, and information management devices. The information collected, managed, and disseminated may include identity information, medical information, skills information, qualification information, certification information, licensure information. Data in the system is stored in multiple formats, allowing for the retrieval of trusted information in an environment that is part of a network or devoid of network connectivity. |
| US08068005B2 |
Direct wireless polling of model trains
A method and apparatus for designating a particular model vehicle for a command function without punching in the ID of the model vehicle. A remote control device is positioned near one of the model vehicles. A limited field transmission occurs between the model vehicle and the remote control device. The device may be a train engine transmitting its train ID periodically via an infrared (IR) transmission. The remote near the train automatically receives the IR transmission of the train ID, so that the next press of a command button will automatically go to that train ID without needing to punch in the ID number. |
| US08068004B1 |
Embedded inductor
An embedded inductor and a method for forming an inductor are described. Spaced apart first stripes are formed substantially parallel with respect to one another as part of a first metal layer. First contacts, second contacts, and third contacts in respective combination provide at least portions of posts. Spaced apart second stripes substantially parallel with respect to one another and to the first stripes are formed as part of a second metal layer located between the first metal layer and the second metal layer. The first stripes, the posts, and the second stripes in combination provide turns of a coil. |
| US08068002B2 |
Coupled electromechanical relay and method of operating same
An electromechanical relay employing a movable first permanent magnet and a nearby third electromagnet is disclosed. The movable first magnet is permanently magnetized and has at least a first end. The third electromagnet, when energized, produces a third magnetic field which is primarily perpendicular to the magnetization direction of the first movable magnet and exerts a magnetic torque on the first magnet to force the first magnet to rotate and closes an electrical conduction path at the first end. Changing the direction of the electrical current in the third electromagnet changes the direction of the third magnetic field and thus the direction of the magnetic torque on the first magnet, and causes the first magnet to rotate in an opposite direction and opens the electrical conduction path at the first end. Multiple magnets can be stacked together to form multi-pole-multi-throw relays. Latching and non-latching types of relays can be formed by appropriately using soft and permanent magnets as various components. |
| US08067990B2 |
Atomic oscillator
An atomic oscillator includes: a gas cell in which a gaseous metal atom is sealed; heating units heating the gas cell to a predetermined temperature and being a first heater and a second heater; a light source of exciting light exciting the metal atom in the gas cell; a light detecting unit detecting the exciting light which has passed through the gas cell; a substrate including at least a temperature controlling circuit for the heating units; a first heater wiring coupling the first heater and the substrate; a second heater wiring coupling the second heater and the substrate; and a third heater wiring coupling the first heater and the second heater. In the atomic oscillator, the gas cell includes a cylindrical portion; and windows which respectively seal openings at both ends of the cylindrical portion and constitute an incident surface and an emitting surface on an optical path of the exciting light. The first heater and the second heater are respectively formed on the windows at an incident surface side and an emitting surface side and made of transparent heating materials. |
| US08067989B1 |
Alternate clock apparatus and methods for improving radio performance
An alternate clock apparatus and method configured to reduce noise in selected frequency bands in an electronic device such as a communication device is described. In one embodiment the alternate clock includes a ring oscillator to generate multiple time shifted signals which may then be combined to generate clock signals at alternate frequencies to a primary reference. A resynchronization circuit may be coupled to the ring oscillator to periodically resynchronize the ring oscillator to a reference signal to reduce alternate clock jitter. |
| US08067987B2 |
Millimeter-wave wideband voltage controlled oscillator
A voltage controlled oscillator-phase lock loop (VCO-PLL) system includes a voltage controlled oscillator (VCO) system implementing four-channel architecture, such that two bands support two channels; a phase-locked-loop (PLL) system; and a mixer system. The VCO system further includes a control circuit; a first cross-coupled oscillator system adapted to receive a source voltage; a second cross-coupled oscillator system adapted to receive the source voltage; and a plurality of isolation buffer systems adapted to protect the first and second cross-coupled oscillator systems. |
| US08067985B2 |
Resonant operating mode for a transistor
The PN junctions of a transistor are biased for operation in the active mode but an initial flow of current reverses the bias of the base-emitter junction causing the transistor to conduct a resonant current with a voltage less than the forward junction voltage of said base-emitter. |
| US08067982B2 |
Transconductance amplifier with improved linearity
The invention relates to a transconductance amplifier, intended to supply current variations di when it receives voltage variations dv, with a desired conversion coefficient Gm called transconductance: Gm=di/dv.The amplifier comprises a PMOS transistor (MP1) and an NMOS transistor (MP2) connected by their drains, their gates both being connected to the voltage input receiving dv; the source of the first transistor is connected to a constant current source (IB1) and to a resistor (R) and to the drain of a third MOS transistor (MN3) of the same type as the first; the sources of the second (MN2) and third (MN3) transistors are commoned, the gate of the third transistor being connected to the drains of the first and second; the output is connected to a circuit (MN4) which mirrors the current of the third transistor.The resulting amplifier has good linearity and can be used in a sample and hold device used to sample charges. |
| US08067971B2 |
Providing additional inputs to a latch circuit
A latch circuit for retaining and transmitting an input data value is disclosed, along with a memory, and a method for retaining and transmitting data. The latch circuit includes a primary input for receiving a data value, an output for outputting the data value, a data transmission path including a transmitting device for transmitting the data value from the primary input to the output, a feedback loop for retaining the data value, the feedback loop including the transmitting device and a further device. The further device is configured to turn on in response to assertion of an activating signal and to turn off in response to no assertion of the activating signal. The feedback loop not retaining data when the further device is turned off, and the feedback loop further including a multiplexer, and the multiplexer is configured to connect either the data transmitting device to the further device and form the feedback loop or to connect a secondary input to the further device and form a secondary data transmission path from the secondary input through the further device and the transmitting device to the output. |
| US08067966B2 |
Voltage controlled delay loop and method with injection point control
A voltage controlled delay loop and method are disclosed for clock and data recovery applications. The voltage controlled delay loop generates clock signals having similar frequency and different phases. The voltage controlled delay loop comprises a plurality of delay elements; and an input that selectively injects a reference clock into any one of the plurality of delay elements. The plurality of delay elements are connected in series, such as in a loop. In one exemplary implementation, each delay element has an associated multiplexer that selects one of the reference clock and a signal from a previous delay element. |
| US08067965B2 |
Clock and data recovery circuit with proportional path
A clock and data recovery circuit includes a phase detector, a charge pump, a loop filter, a voltage-controlled oscillator and a frequency divider. The voltage-controlled oscillator includes a current mirror, a control circuit, a current modulation module and a current-controlled oscillator. The current mirror has a current-controlling path and a current-outputting path. The current-controlling path and the current-outputting path are in a proportional relationship. The control circuit is used for adjusting the current flowing through the current-controlling path according to the control voltage. The current modulation module is used for generating a differential current according to the judging signal. The current-controlled oscillator is used for adjusting the phase of the second output clock signal according to the sum of the differential current and the current flowing through the current-outputting path. |
| US08067963B2 |
Sense-amplifier control circuit and controlling method of sense amplifier
A sense amplifier control circuit includes an initial-voltage setting circuit configured to set a control signal to an initial voltage, the control signal controlling a sensing operation of a sense amplifier, and a control-signal-level adjusting circuit configured to first change a voltage level of the control signal from the initial voltage to a voltage level at which the sense amplifier can execute a current sensing, and is configured to second change, after a predetermined time elapses, the voltage level at which the sense amplifier can execute the current sensing to a voltage level at which the sense amplifier can execute a voltage sensing. |
| US08067962B2 |
Semiconductor integrated circuit device
A semiconductor integrated circuit device has a combinational logic circuit including one or plural logic cells connected in series. At least one of the logic cells includes a standard cell which includes a MIS transistor, an input terminal to which an output signal from a previous stage is inputted as an input signal, and an output terminal. A first conductivity-type first MIS transistor which is provided between the output terminal of the standard cell and a first power supply voltage, the first MIS transistor including a control terminal to which a circuit control signal is inputted, and the first MIS transistor supplying the first power supply voltage to the output terminal of the standard cell based on the circuit control signal in order to bring the standard cell into an operation-stopped state. A second conductivity-type second MIS transistor cuts off a leakage current of the MIS transistor in the standard cell. |
| US08067961B2 |
Level conversion circuit for converting voltage amplitude of signal
In a level conversion circuit, two P channel MOS transistors form a current mirror circuit. When an input signal rises from the “L” level to the “H” level, an N channel MOS transistor connected to a drain of one P channel MOS transistor is brought out of conduction to prevent a leak current from flowing through two P channel MOS transistors, which decreases a power consumption. In addition, when the input signal rises from the “L” level to the “H” level, a P channel MOS transistor connected to a drain of the other P channel MOS transistor is brought into conduction to fix a potential of a node of the drain of the other P channel MOS transistor to the “H” level, which prevents the potential of the node from becoming unstable. |
| US08067954B2 |
Fault tolerant integrated circuit architecture
The exemplary embodiments provide a resilient integrated circuit. An exemplary IC comprises a plurality of composite circuit elements, a state machine element (SME), and a plurality of communication elements. Each composite circuit element comprises an element interface and a selected circuit element which may vary by element type, and which may be configurable. The state machine element assigns various functions based on element type, such as assigning a first configuration to a first element type, assigning a second configuration to a second element type, and providing a first data link for the corresponding assignments. In response to detection of a fault or failure, the state machine element re-assigns the first configuration to another composite circuit element and creates a second data link for performance of the same function. The assignment, routing, fault detection, and re-assignment and data re-routing can occur in real time for a wide variety of programs and algorithms, providing for the IC to continue the same functioning despite defects which may arise during operation. |
| US08067948B2 |
Input/output multiplexer bus
An input/output (“I/O”) system includes a plurality of input/output (“I/O”) ports, measurement circuitry, and an I/O multiplexer bus. The measurement circuitry is coupled to measure one or more electrical properties of one or more devices to be externally coupled to one or more of the I/O ports. The I/O multiplexer bus is coupled between the I/O ports and the measurement circuitry. The I/O multiplexer bus is programmable to selectively couple the measurement circuitry to any of the I/O ports. |
| US08067940B2 |
Tubular magnetic resonance surface coil, and method and system for processing signals therefrom
In a method and system for processing radio frequency signals of a tubular surface coil, the N channels of coil output signals are generated based on M channels of radio frequency signals acquired by M coil units in the tubular surface coil, wherein N is an even number greater than 1 and is less than or equal to M, and the N channels of coil output signals can be divided into N/2 pairs, with the two channels of coil output signals in each of the pairs respectively coming from the coil units located at symmetrical positions of the tubular surface coil. The respective modulus values of the two channels of coil output signals in said each pair of coil output signals are multiplied to obtain N/2 products which are then summed, and the square root of the summed result is computed, so as to generate a lateral cross-sectional image according to the computed result of square root. The signal strength in an imaging area and the uniformity of signal to noise ratio are thereby improved. |
| US08067939B2 |
Magnetic resonance gradient coil formed by two different types of conductors
A gradient coil of a magnetic resonance apparatus has a first conductor structure and a second conductor structure connected with one another so that windings of the gradient coil are formed. The first conductor structure is formed exclusively of planar, electrically conductive elements that are insulated from one another. The second conductor structure is formed exclusively of conductive wires insulated from one another. |
| US08067938B2 |
Microcoil NMR detectors
The present invention provides resonance circuits, detection devices incorporating such circuits, and methods for their design, construction, and use. |
| US08067923B2 |
Rechargeable battery assembly having a data and power connector plug
A rechargeable battery assembly comprises a rechargeable battery unit and a data and power connector plug. The battery assembly has a deployed configuration in which the battery assembly has the general form of and functions as a conventional battery format, and a recharge configuration in which the data and power connector plug is made accessible to enable said connector to be connected to a suitable receptacle on a computing or peripheral device for recharging of the battery. |
| US08067918B2 |
Servomotor controller for controlling periodic reciprocation
A servomotor controller capable of properly generating reference positions, by which learning control of angle based method may be applied to the periodically reciprocating motion of an object. The learning controller obtains a first positional deviation of a driven object at every predetermined sampling period of time, and the first positional deviation is converted, by a first converting part, to a second positional deviation associated with each reference position in one periodic reciprocating motion of the driven object. After a first correction amount of an immediately previous reciprocating motion of the driven object, stored in a memory, is added to the second positional deviation, the second positional deviation is stored in the memory as a renewed first correction amount. The first correction amount is converted to a second correction amount associated with the sampling period, by a second converting part. |
| US08067914B2 |
Multizone capacitive anti-pinch system
An anti-pinch assembly is used for a closure panel movable between open and closed positions on a motor vehicle. A controller operably connected to the closure panel controls operation thereof. A position sensor connected to the controller indicates the position of the closure panel between the open and closed positions. A capacitive sensor mounted on the vehicle and connected to the controller provides an output signal to the controller indicative of the presence of a foreign object in the path of the closure panel. The controller varies the function of the capacitive sensor through a plurality of threshold levels as a function of the position of the closure panel as indicated by the position indicator. In a critical zone of travel with the closure panel nearing the closed position, the capacitive sensor can be utilized in either a contact mode or a non-contact mode or a combination of both. |
| US08067913B2 |
Power tool
The controller determines the presence or absence of operation of the trigger switch according to an ON/OFF state of the main contact of the trigger switch and designating the rotation speed of the motor based on a signal outputted from the speed contact. The controller stops the rotation of the motor, after the trigger switch is activated and the main contact is turned ON and the motor is driven according to a signal outputted from the speed contact, when an OFF state of the main contact is detected, only in the case where a signal value outputted from the speed contact is a predetermined value or less. |
| US08067912B2 |
Interface cord and system including an interface cord
An interface cord is operable to connect an external controller to an electrical machine. The interface cord includes a first connector having a first pin configuration, a cable coupled to the first connector, a second connector coupled to the cable and having a second pin configuration different from the first pin configuration, and a circuit board with a programmable electrically coupled in circuit between the first connector and the second connector. |
| US08067904B2 |
Electronic ballast with dimming control from power line sensing
The present invention discloses an electronic ballast with dimming control from power line sensing for a fluorescent lamp, comprising: a control voltage generator, used to generate a control voltage according to a switching count of a power line; an oscillator, used to generate an oscillating signal, wherein the oscillating signal is of a fixed frequency and has a rising voltage portion and a falling voltage portion; and a comparator, used to generate a high side gating signal according to voltage comparison of the oscillating signal and the control voltage. |
| US08067903B2 |
Method and driving unit for driving a gas discharge lamp
Disclosed is a method for driving a gas discharge lamp in at least two operation modes, including the step of applying an alternating voltage to the gas discharge lamp, the alternating voltage having a first polarity during a first time interval and a second polarity opposite to the first polarity during a second time interval. The first time interval and the second time interval are repeated alternately. During a second operation mode, the electrical power being provided to the gas discharge lamp is smaller compared to a first operation mode, and the duration of the first time interval is at least a multiple of the duration of the second time interval. |
| US08067901B2 |
Bi-directional light emitting diode drive circuit in pulsed power parallel resonance
The present invention is characterized by using capacitive, inductive or resistive impedance to constitute the first impedance which is series connected with the second impedance constituted by parallel connecting the capacitive and inductive impedances that appears parallel resonance with the pulsed period to receive pulsed power, thereby to form a divided bidirectional power at the two ends of the first and second impedances, so as toe drive the bidirectional conducting light emitting diode. |
| US08067899B2 |
Circuit arrangement and method for operating at least one first and a second lamp
A circuit arrangement for operating at least one first and second lamp each provided with a first and second coil electrode includes a first and second terminal for the first coil electrode of the first lamp, a first and second terminal for the second coil electrode of the first lamp, a first and second terminal for the first coil electrode of the second lamp, a first and second terminal for the second coil electrode of the second lamp, at least one supply connection for supplying voltage to the respective first coil electrode of the at least one first and second lamp, and at least one preheating device for the respective first coil electrode of the at least one first and second lamp. The second terminal of the first coil electrode of the first lamp is coupled to the second terminal of the first coil electrode of the second lamp while the preheating device encompasses a first preheating inductor and a second preheating inductor. |
| US08067898B2 |
Power supply device for light elements and method for supplying power to light elements
Disclosed is a power supply device for light elements, including a first light element having a first color, a second light element having a second color, and a third light element having a third color. The power supply includes a power supply unit, a controllable switch coupled in series to the third light element in parallel to the second light element. The power supply unit has a first and a second output such that the first light element is coupled to the first output and the second and third light elements are coupled to the second output. The power supply unit provides adjustable output signals at the first and said second output such that the third light element radiates light when the switch is closed. |
| US08067897B2 |
Backlight assembly and method of driving the same
A backlighting assembly for an LCD display is divided into a plurality of selective dimming areas each having a respective plurality of light generating blocks. A plurality of driving units supply power to the light generating blocks. The light generating blocks are grouped into light source groups. Each of the driving units supplies power to at least one light generating block in a first light source group and a second light generating block in a second light source group but not to all the light generating blocks in any one light source group. Light generating blocks connected to a same driving unit may be distributedly arranged to be nonadjacent to one another. Plural driving units are used to fully power a brightly lit one dimming area, thereby reducing the loads on the individual driving units and preventing overheating. |
| US08067892B2 |
Method of forming a corona electrode substantially of chemical vapor deposition silicon carbide and a method of ionizing gas using the same
A method is provided for forming a corona-producing emitter electrode by depositing substantially pure silicon carbide by CVD and forming a corona-producing emitter electrode with the deposited silicon carbide. In addition, a method of forming a corona-producing gas ionizer is provided by providing a corona electrode formed from CVD silicon carbide, electrically coupling the corona electrode to a high voltage power supply, and providing an AC or DC voltage from the high voltage power supply to the corona electrode. Furthermore, a method of ionizing gas in an environment is provided by providing a corona-producing ionizer emitter electrode formed substantially of CVD silicon carbide, electrically coupling the electrode to a high voltage power supply, and providing an AC or DC voltage from the high voltage power supply to the electrode. |
| US08067890B2 |
Organic electroluminescence structure having a height difference between surfaces of a control device and an organic electroluminescence device
An organic electroluminescence structure comprises a first substrate, an organic electroluminescence device, and a control device. Forming either a lifting layer under the control device or a recess under the organic electroluminescence device, or forming both of them, creates a difference between their tops, in order to reduce the dark spots and promote the yield of the end product. The lifting layer preferably has a thickness greater than about 0.5 micro meters and the recess has a depth ranges of about 0.1 micro meters to about 100 micro meters. Alternatively, the height difference between the upper surfaces of the control device and the organic electroluminescence device is controlled to be greater than about 2 micro meters or substantially equal to 2 micro meters. |
| US08067886B2 |
Composite optical destructive electrode for high contrast electroluminescent devices
The present invention in one embodiment introduces a composite optical destructive layer (35) into the electroluminescent device which reduces the reflection of ambient light from the device. The composite optical destructive layer (35) is advantageously made of materials already found in the manufacturing process of the electroluminescent device (70) and also by manufacturing processes inherent in the manufacture of the device. More particularly, the composite optical destructive layer (35) is made from a variant of a parent material used to form one of the electrodes (12) of the electroluminescent device. The variant material differs from the parent material in that the variant material is oxygen deficient. This oxygen deficiency in the variant material causes the variant material to have a change in refractive index from that of the parent material. The composite optical destructive layer (35) that is made from the variant material is then able to absorb incident ambient light as well as reflected ambient light from the electroluminescent device (70). |
| US08067885B2 |
Organic EL device and display
An organic EL device and display are provided. A red light emitting layer, a green light emitting layer, a blue light emitting layer are laminated in this order between an anode and a cathode, and an intermediate layer “a” formed by use of an organic material is provided between the green light emitting layer and the blue light emitting layer. The HOMO-LUMO energy gap in the intermediate layer “a” is greater than the HOMO-LUMO energy gap of a green light emitting material constituting the green light emitting layer. In addition, the intermediate layer “a” has a hole transporting property. In the case of configuring a display by use of the organic EL devices, color filters are provided on the light take-out surface side. This makes it possible to provide an organic EL device with which light emission components for three colors of red, green and blue with a good balance suited to use for a full-color display can be obtained at a high luminance. |
| US08067872B2 |
Permanent magnet rotor having slanted or curved grooves
The invention relates to a permanent magnet rotor for an electric motor, in which the permanent magnets inside the rotor extend parallel to the rotation axis of the rotor, and in the area of the radially outer longitudinal edges of the permanent magnets, grooves that are open to the outside are formed on the outer periphery of the rotor. These groves are each, in a peripheral direction, slanted or curved with regard to the longitudinal edge of the adjacent permanent magnets. The center line of each groove intersects the longitudinal edge of the adjacent permanent magnet at least once. The grooves on the outside of the rotor have, in the peripheral direction, a smaller width than in an area of the groove situated radially further inside, and the cross-sectional shape of the groove is constant over the length of the rotor. The invention also relates to a method for producing a rotor of the aforementioned type. |
| US08067864B2 |
Electric motor sealing configuration
An electric motor for driving an inertia separator is provided, including a stator and a rotor. The stator is arranged in a stator space enclosed by a stator housing. The rotor is arranged in a rotor space concentrically with the stator with regard to an axis of rotation. A ring gap is formed radially between the rotor and the stator such that it separates the stator space from the rotor space. A housing bottom includes a nonmagnetic section extending through the ring gap. An inertia separator includes a second rotor operably connected to the rotor. A separator housing encloses a void containing the second rotor, wherein the housing bottom is arranged on the separator housing on a side facing the electric motor such that the nonmagnetic section of the housing bottom defines an opening in the rotor space that is oriented towards the void. |
| US08067861B2 |
Interface device for host device, interface device for slave device, host device, slave device, communication system and interface voltage switching method
A communication system in which an operating voltage can be selected from a plurality of interface voltages enables an interface voltage to be switched in a stable manner during operation of the system. When the interface voltage is to be switched, a host device (1) and a slave device (2) perform the switching while maintaining the signal level of buses in a stable manner. This structure enables the communication system to switch an interface voltage using a small number of signal lines. |
| US08067856B2 |
Power management system
A power supply system includes at least one power supply module and at least one redundant power supply module. A power supply module may include a charging resistor in parallel with an OR-ing device to keep all filter capacitors charged as long as at least one power supply module remains operational. This may avoid current spikes at turn on and may enable the redundant module to turn on without using soft start. |
| US08067850B2 |
Method for creating a low fluid pressure differential electrical generating system
This invention involves a method of creating a hydroelectric turbine system that is capable of producing electricity while sustaining a majority of the fluid flow or hydraulic pressure within the pipe line or pipe network driving the system. The system's objective is to shave as little pressure as possible from an enclosed pipe system that requires pressure to operate and function properly. More particularly, this invention relates to a hydroelectric turbine generator system wherein the system is specially designed and configured with an unique impeller and fluted turbine housing that enable a generator device to produce a particular amount of electric current and voltage, while yet minimizing flow restriction and pressure loss to the fluid pressure driving the system. |
| US08067849B2 |
Wave energy converter with internal mass on spring oscillator
A wave energy converter (WEC) system includes a shell containing an internal oscillator comprised of a reaction mass suspended from the shell by an elastic spring in parallel with a constant force spring. The constant force spring provides a relatively constant force (Fc) to counterbalance the static weight of the reaction mass and reduce the extension “static” length of the elastic spring while the elastic spring exerts a force (Fes) on the reaction mass that is proportional to the displacement, x, of the elastic spring. A power take-off (PTO) device, located within the shell, coupled between the shell and the internal oscillator converts their relative motion into electrical energy. |
| US08067848B1 |
Bicycle adapter mobile telephone charger
A bicycle-based mobile telephone charging apparatus is herein disclosed comprising a frame-mounted electrical generator utilizing contact with a tire portion in a conventional manner to produce power to be supplied to a voltage regulator and charging circuit located in a frame-mounted pouch near a front of the bicycle. Interconnecting cabling is routed along the bicycle frame between the generator and the pouch. It is envisioned that a specialized cable commonly provided with a cellular phone or other electronic devices, connects the apparatus to a charging jack portion of the mobile telephone. The mobile phone is then placed in the pouch allowing the batteries to be charged while the user rides the bicycle. |
| US08067846B2 |
Automotive wind powered generator
The Wind Powered Generator System is a combination of many common automotive parts. Automotive wind power is a new area and incorporates a roof carrier system that have generators mounted on the crossbar or the roof system. The air velocity or wind turns the fan blade when either vehicle is in motion or not, producing an electrical current. |
| US08067844B2 |
Engine generator set
An engine generator set comprises an internal combustion engine having an output shaft that is coupled to an electrical generator for producing an AC electrical power output. The engine is operable to rotate the shaft at a first rotational speed so that the generator is driven to produce electrical power at a first frequency and a second rotational speed at which the generator is driven to produce electrical power at a second frequency. An exhaust gas turbocharger is operatively connected to the engine and has a compressor with a housing that defines a gas inlet. At least two guide, vane assemblies that are releasably and interchangeably connectable to the inlet to match the compressor performance with the first or second engine speed. The guide vanes of the first guide vane assembly extend in a downstream direction towards the impeller wheel at an angle relative to the inlet that is different to the corresponding angle of the guide vanes second guide vane assembly. |
| US08067843B2 |
Wireless mouse with power generating function
A wireless mouse includes a magnetic ball, a power generating device and a power storage device. The power generating device includes an inductive coil, being dome-shaped and partially covering the magnetic ball and configured for generating inductive voltage following the movement of the magnetic ball, and a converting unit, being configured for converting the inductive voltage to a stabilized DC voltage. The power storage device electrically is coupled to the power generating device and configured for being charged by the converting unit using the stabilized DC voltage and provide power for the wireless mouse. |
| US08067842B2 |
Integrated circuit package, notably for image sensor, and method of positioning
The invention relates to the fabrication of integrated circuits in general, and notably the circuits of image sensors intended to form the electronic core of photographic apparatus or cameras. The chip is first aligned with respect to the package and then the package is aligned with respect to the optical system. The alignment of the chip with respect to the package is done optically. The alignment of the package with respect to the system is done mechanically with respect to the edges of the package. According to the invention, provision is made for optical marks to be provided on the package, these marks each having an edge aligned with a lateral edge of the package, so as to minimize the positioning errors which would be due to inaccurate positioning of the chip with respect to the edges of the package. |
| US08067840B2 |
Power amplifier assembly
The power amplifier module comprises a laminate substrate comprising thermal vias and terminals, as well as a platform device with an interconnection substrate of a semiconductor material. This substrate is provided with electrical interconnects at a first side, and having been mounted on the laminate substrate with an opposite second side. Electrically conducting connections extend from the first to the second side through the substrate. A power amplifier device is attached to the second side of the substrate. One of the electrically conducting connection through the interconnection substrate is a grounding path for the power amplifier, while a thermal path is provided by the semiconductor material. There is an optimum thickness for the interconnection substrate, at which both a proper grounding and a acceptable thermal dissipation is effected. |
| US08067835B2 |
Method and apparatus for manufacturing semiconductor module
Disclosed herewith is a semiconductor module manufacturing apparatus capable of reducing occurrence of warping of the wiring substrate, etc., as well as occurrence of failures of bonding between the wiring substrate and semiconductor chips, etc. without lowering the productivity. The semiconductor module manufacturing apparatus employs a batch reflowing process that heats one, two, or more wiring substrates and at least two or more semiconductor chips or semiconductor devices simultaneously. After the heating process, the semiconductor chips or semiconductor devices are heated and bonded on the wiring substrate. The apparatus includes at least a stage for chucking the wiring substrate fixedly; a heat source for heating the semiconductor chips or semiconductor devices out of contact therewith; and a controller for controlling the heating value of the heat source. |
| US08067834B2 |
Semiconductor component
In various embodiments, semiconductor components and methods to manufacture these components are disclosed. In one embodiment, a method to manufacture a semiconductor component is disclosed. The semiconductor includes a heat sink and a semiconductor die that has a first terminal on a top surface of the semiconductor die, a second terminal on the top surface of the die, and a third terminal on the bottom surface of the die. The method includes attaching a first portion of a leadframe structure to the first terminal of the semiconductor die. The method further includes attaching the second terminal of the semiconductor die to the heat sink after the attaching of the first portion of the leadframe structure to the first terminal of the semiconductor die, wherein the leadframe structure is spaced apart from the heat sink and is electrically isolated from the heat sink. Other embodiments are described and claimed. |
| US08067833B2 |
Low noise high thermal conductivity mixed signal package
An improved microelectronic assembly (100) and packaging method includes a device package for housing a semiconductor die or chip, (105), an array of passive electronic components (305-355) operating in cooperation with the flip chip semiconductor die (105) and housed inside the device package to decouple noise from input signals, and a heat spreader (195) disposed between a top surface of the semiconductor die (105) and a package cover (185). The semiconductor die (105) is configured as a flip chip die and the device package includes a package substrate (110) configured as a ball grid array. The improved microelectronic device (100) reduces parasitic inductance in electrical interconnections between the semiconductor die and an electrical system substrate (115) and reduces signal noise in mixed signal high frequency analog to digital converters operating at clock rates above 1 GHz. |
| US08067827B2 |
Stacked microelectronic device assemblies
An assembly of microelectronic devices and method for forming an assembly of microelectronic devices. In one embodiment, the method includes positioning a first packaged microelectronic device adjacent to a support member having support member circuitry, with the first packaged microelectronic device having a first microelectronic die at least partially encased in a first encapsulant to define a first package configuration. The method can further include electrically connecting the first packaged microelectronic device to a first portion of the support member circuitry and positioning at least proximate to the first packaged microelectronic device a second packaged microelectronic device having a second microelectronic die at least partially encased in a second encapsulant to define a second package configuration different than the first package configuration. The first packaged microelectronic device can be positioned between the support member and the second packaged microelectronic device. The second packaged device can be coupled directly to a second portion of the support member circuitry. Accordingly, the second packaged microelectronic device can be connected directly to the support member without connecting the second packaged device to the first packaged device. |
| US08067825B2 |
Integrated circuit package system with multiple die
An integrated circuit package system includes providing die; forming leads adjacent the die; forming a die paddle adjacent the leads with the die thereover; and forming a cavity for isolating one of the die and a die attach segment of the die paddle. |
| US08067820B2 |
Silocon wafer supporting method, heat treatment jig and heat-treated wafer
Provided is a method applicable to the production of silicon wafers having crystal orientation <100> or <110> and consisting in specifying wafer-supporting positions on the occasion of heat treatment in a vertical heat treatment furnace as well as a heat treatment jig for use in carrying out that method. It becomes possible to suppress the shear stress which contributes to the extension of the slip generated at each wafer-supporting element contact point as an initiation, suppress slip growth and thus markedly improve the yield of heat-treated silicon wafers. The heat-treated wafer obtained by using the supporting method and the heat treatment jig has few slip, in particular has no long and large slip, and is high in quality. |
| US08067818B2 |
Nonplanar device with thinned lower body portion and method of fabrication
A nonplanar semiconductor device having a semiconductor body formed on an insulating layer of a substrate. The semiconductor body has a top surface opposite a bottom surface formed on the insulating layer and a pair of laterally opposite sidewalls wherein the distance between the laterally opposite sidewalls at the top surface is greater than at the bottom surface. A gate dielectric layer is formed on the top surface of the semiconductor body and on the sidewalls of the semiconductor body. A gate electrode is formed on the gate dielectric layer on the top surface and sidewalls of the semiconductor body. A pair of source/drain regions are formed in the semiconductor body on opposite sides of the gate electrode. |
| US08067815B2 |
Aluminum copper oxide based memory devices and methods for manufacture
Memory devices are described along with methods for manufacturing. A memory device as described herein includes a first electrode and a second electrode. The memory device further includes a diode and an anti-fuse metal-oxide memory element comprising aluminum oxide and copper oxide. The diode and the metal-oxide memory element are arranged in electrical series between the first electrode and the second electrode. |
| US08067813B2 |
Integrated MIS photosensitive device using continuous films
An integrated photosensitive device with a metal-insulator-semiconductor (MIS) photodiode constructed with one or more substantially continuous layers of semiconductor material and with a substantially continuous layer of dielectric material. |
| US08067804B2 |
Semiconductor device having an SOI structure, manufacturing method thereof, and memory circuit
The present invention provides a semiconductor device capable of suppressing a body floating effect, and a manufacturing method thereof. A semiconductor device having an SOI structure includes a silicon substrate, a buried insulating layer formed on the silicon substrate, and a semiconductor layer formed on the buried insulating layer. The semiconductor layer has a body region of a first conduction type, a source region of a second conduction type and a drain region of the second conduction type, and a gate electrode is formed on the body region between the source region and the drain region via a gate oxide film. The source region includes an extension layer of the second conduction type, and a silicide layer which makes contact with the extension layer at its side face, and a crystal defect region is formed on a region of a depletion layer generated in a boundary portion between the silicide layer and the body region. |
| US08067797B2 |
Variable threshold trench IGBT with offset emitter contacts
A trench type IGBT as disclosed herein includes a plurality of channel regions having one threshold voltage for the normal operation of the device and a plurality of channel regions having a threshold voltage higher than the threshold voltage for the normal operation of the device. |
| US08067791B2 |
Semiconductor device and method for fabricating the same
A semiconductor device formed by the steps of: forming a dummy electrode 22n and a dummy electrode 22p; forming a metal film 32 on the dummy electrode 22p; conducting a thermal treatment at a first temperature to substitute the dummy electrode 22n with an electrode 34a of a material containing the constituent material of the metal film 32; forming a metal film 36 on the dummy electrode 22n; and conducting a thermal treatment at a second temperature, which is lower than the first temperature and at which an interdiffusion of constituent materials between the electrode 34a and the metal film 36 does not take place, to substitute the second dummy electrode with an electrode 34b of a material containing the constituent material of the metal film 36. |
| US08067786B2 |
Gallium nitride material devices including conductive regions
Semiconductor structures comprising a III-nitride (e.g., gallium nitride) material region and methods associated with such structures are provided. In some embodiments, the structures include an electrically conductive material (e.g., gold) separated from certain other region(s) of the structure (e.g., a silicon substrate) by a barrier material in order to limit, or prevent, undesirable reactions between the electrically conductive material and the other component(s) which can impair device performance. In certain embodiments, the electrically conductive material may be formed in a via. For example, the via can extend from a topside of the device to a backside so that the electrically conductive material connects a topside contact to a backside contact. The structures described herein may form the basis of a number of semiconductor devices including transistors (e.g., FET), Schottky diodes, light-emitting diodes and laser diodes, amongst others. |
| US08067785B2 |
Organic light emitting apparatus and method of producing the same
Provided are an organic light emitting apparatus for use in, for example, a flat device display, and a method of producing the apparatus. The organic light emitting apparatus has sides formed by division at ends of its substrate. Three-dimensional portions are formed on the surface of the substrate along the sides. An inorganic sealing layer is formed to extend toward the three-dimensional portions. |
| US08067782B2 |
LED package and light source device using same
An exemplary LED package includes a dielectric plate, a heat conductor, a first planar electrode and a second planar electrode, a LED chip, and metal wires. The dielectric plate comprises a receiving groove defined therein. The heat conductor is positioned in the dielectric plate opposite to the receiving groove, and the heat conductor comprises a holding portion exposed on bottom of the receiving groove. The first and second planar electrodes are respectively received in the dielectric plate extending to the receiving groove and are spaced from the heat conductor. The first and second electrodes are respectively electrically connected to the LED chip by the metal wires. The LED chip is mounted on the holding portion of the heat conductor. |
| US08067780B2 |
Light emitting device and the manufacture method thereof
This invention provides a light-emitting element and the manufacture method thereof. The light-emitting element is suitable for flip-chip bonding and comprises an electrode having a plurality of micro-bumps for direct bonding to a submount. Bonding within a relatively short distance between the light-emitting device and the submount can be formed so as to improve the heat dissipation efficiency of the light-emitting device. |
| US08067777B2 |
Light emitting diode package assembly
An electrical device containing multiple light emitting diode (LED) dies each having respective first and second connectors suitable to receive current through the LED die. A common base layer of a first electrically conductive material has cavities into which at least one LED die is mounted with its second connector electrically connected by a conductive bonding material to the first conductive material of the base layer. One or more over-layer sections of a second electrically conductive material each are electrically connected by a bond to at least one of the first connector of an LED die. And an insulator electrically separates the first conductive material of the base layer from the second conductive material of over-layer sections. |
| US08067776B2 |
Method of manufacturing semiconductor device and semiconductor device manufactured thereof
Methods of manufacturing a semiconductor device including a semiconductor substrate and a hetero semiconductor region including a semiconductor material having a band gap different from that of the semiconductor substrate and contacting a portion of a first surface of the semiconductor substrate are taught herein, as are the resulting devices. The method comprises depositing a first insulating film on exposed portions of the first surface of the semiconductor substrate and on exposed surfaces of the hetero semiconductor material and forming a second insulating film between the first insulating film and facing surfaces of the semiconductor substrate and the hetero semiconductor region by performing a thermal treatment in an oxidizing atmosphere. |
| US08067774B2 |
Thin film transistor panel and method of manufacturing the same
After forming a signal line including aluminum, an upper layer of an oxide layer including aluminum that covers the signal line is formed in the same chamber and by using the same sputtering target as the signal line, or a buffer layer of an oxide layer including aluminum is formed in a contact hole exposing the signal line during the formation of the contact hole. Accordingly, the contact characteristic between an upper layer including indium tin oxide (“ITO”) or indium zinc oxide (“IZO”) and the signal line may be improved to enhance the adhesion therebetween while not increasing the production cost of the thin film transistor (“TFT”) array panel. |
| US08067771B2 |
Semiconductor device and method for manufacturing the same
A semiconductor device includes a p-type TFT having a first semiconductor layer, and an n-type TFT having a second semiconductor layer. A tilted portion, which is widened toward the insulating substrate side, is formed in at least a part of an outer edge portion of the first semiconductor layer. A tilt angle of a surface of the tilted portion to a surface of an insulating substrate, which is an angle formed inside the first semiconductor layer, is smaller than an angle of a side surface of an outer edge portion of the second semiconductor layer to the surface of the insulating substrate, which is an angle formed inside the second semiconductor layer. |
| US08067766B2 |
Multi-level memory cell
A multi-level memory cell having a bottom electrode, a first dielectric layer, a plurality of memory material layers, a plurality of second dielectric layers, and an upper electrode is provided. The bottom electrode is disposed in a substrate. The first dielectric layer is disposed on the substrate and has an opening exposing the bottom electrode. The memory material layers are stacked on a sidewall of the first dielectric layer exposed by the opening and are electrically connected to the bottom electrode. The second dielectric layers are respectively disposed between every adjacent two memory material layers and are located on the sidewall of the first dielectric layer. The upper electrode is disposed on the memory material layers. A manufacturing method of the multi-level memory cell is further provided. A multi-bit data can be stored in a single memory cell, and both the process complexity and the cost are reduced. |
| US08067765B2 |
Organic light emitting element and organic light emitting device including the same
An organic light emitting element and an organic light emitting device including the same is provided. At least one p-type or n-type overdoping layer is formed between two light emitting members forming a p-n junction in the organic light emitting element. |
| US08067760B2 |
Impulse analysis for flow sensor-based fluid control system
A fluid flow control system using flow rate changes to extract additional information from an in-line flow sensor. The system provides the ability to determine a position of a movable flow sensor element of a flow sensor by illuminating a photosensitive pixel array with a light source to create a first set of pixel intensity values introducing an abrupt change to the fluid driving pressure, illuminating the photosensitive pixel array with a light source to create a second set of pixel intensity values, and calculating the difference between the first and second sets of pixel intensity values as a function of pixel position. |
| US08067759B1 |
Radiation protective vest
A radiation protective vest includes a back panel with flaps at opposite lower sides and a pair of front panels, each panel containing radiation shielding material. Each front panel has an inner straight edge and a flap at a lower outer side. The front and back panels are connected to form the vest. A first strap is attached to one front panel and a second strap is attached to the other front panel. The second strap is threaded in a first sleeve attached to the inside of the back panel and the first strap is threaded in a second sleeve attached to the inside of the back panel. A fastener is provided on the free ends straps. When the vest is worn, the flaps of the front panels press against a user's waist and the back panel flaps overlap the front panels. |
| US08067757B2 |
Extreme ultraviolet light source apparatus and method of adjusting the same
An extreme ultraviolet light source apparatus includes a main body including a supply section to which an extreme ultraviolet radiation seed is supplied, and an emission part configured to emit extreme ultraviolet, an excitation unit provided in the main body and configured to generate a plasma by exciting the extreme ultraviolet radiation seed, an optical condensing unit provided in the main body and configured to converge extreme ultraviolet, which is radiated from the plasma, at the emission part, a trap provided between the excitation unit and the optical condensing unit, a first positioning mechanism connected to the trap and configured to adjust at least one of a position and an angle of the trap, and a measuring unit configured to measure a far field distribution image of the plasma on the basis of the extreme ultraviolet which is emitted from the emission part, thereby to operate the first positioning mechanism. |
| US08067754B2 |
Photoconductive device
A photoconductive device comprising a photoconductive portion for generating carriers by applied excitation light; a resistance portion in contact with the photoconductive portion; a first conductive portion in contact with the resistance portion; and a second conductive portion that is provided so as to have a gap with respect to the first conductive portion and is in contact with the photoconductive portion. |
| US08067745B2 |
X-ray detector and manufacturing method thereof
An X-ray detector includes; a panel having a plurality of photo-detecting pixels generating electrical signals in response to the detection of X-rays, a gate driver providing a gate signal to the plurality of photo-detecting pixels, wherein the photo-detecting pixels output the electrical signals in response to the gate signal, a readout integrated circuit reading out the electrical signal in response to the gate signal, a main board including a controller receiving the electrical signal and converting the electrical signal to an image signal, a film attached to the panel and the main board, the film including a signal line electrically connecting the readout integrated circuit to the panel and main board, wherein the readout integrated circuit is mounted on the film, and a shielding layer covering the film and comprising a conductive material, wherein the shielding layer prevents externally applied electromagnetic signals from passing through the film. |
| US08067742B2 |
Apparatus and method for detection, location, and identification of gamma sources
An apparatus for detecting and determining a source azimuth for gamma radiation includes at least two scintillation crystals at angular offsets and directed toward a common plane of detection, photodetectors adjacent to each of the scintillation crystals for converting the light response of the scintillation crystals into distinct electrical signals, and a digital processing system configured to analyze spectral data from each electrical signal produced for each crystal. The digital processing system monitors a finite number of spectral windows corresponding to a selected set of radioisotopes, and uses one or more of the electrical signals to determine a signal intensity and a likely source azimuth for a detected radioisotope in the plane of detection. Another scintillation crystal directed outside of the common plane of detection may be used for three-dimensional detection. Related methods for detection and location of gamma ray sources are discussed. |
| US08067740B2 |
Image sensor and manufacturing method thereof
An image sensor includes a semiconductor substrate; first pixels laid out above cavities provided within the semiconductor substrate, the first pixels converting thermal energy generated by incident light into an electric signal; supporting parts connected between the first pixels and the semiconductor substrate, the supporting parts supporting the first pixels above the cavities; and second pixels fixedly provided on the semiconductor substrate without via the cavities, wherein a plurality of the first pixels and a plurality of the second pixels are laid out two-dimensionally to form a pixel region, and each of the second pixels is adjacent to the first pixels. |
| US08067739B2 |
Photoconductive element for generation and detection of terahertz wave
A photoconductive element for generating or detecting a terahertz wave comprises a carrier generation layer for generating carriers on light irradiation, a pair of conductive electrodes provided in opposition on one face of the carrier generation layer, each containing a strip line, a pair of conductive antennas placed in opposition with a gap for light irradiation onto the carrier generation layer, each being joined to the electrodes, a pair of conductive adjusting stubs for adjusting a propagation state of the terahertz wave generated or detected by the carriers, wherein each of the adjusting stubs has a length of not longer than the wavelength λ of the terahertz wave generated by the carriers, and is placed at a distance of not more than the wavelength λ from a joint between the antenna and the electrode. |
| US08067738B1 |
Space based calibration transfer spectroradiometer
A Space-based Calibration Transfer Spectroradiometer (SCATS) instrument that establishes a maintainable SI traceable radiometric calibration on-orbit with long-term stability accuracy, such as is required for long term climate monitoring missions, is provided. The SCATS instrument includes sensors that directly measure the highly stable solar irradiance and/or the lunar irradiance, and the Earth radiance through an invariant instrumental optical path. This common path measurement concept eliminates uncertainties associated with the calibration and degradation of intervening solar attenuation elements that represent the current state of the art. The SCATS instrument can be used to calibration of hyperspectral and multi-spectral sensors operating from the ultra-violet to long wave infrared. A suitable selection of detectors and filters enables this wide wavelength application. |
| US08067737B1 |
Photonic detector, imaging system and method employing plasmonic resonance absorption
A photonic detector, a photonic imaging system and a method of photonic detection employ plasmonic resonant absorption to detect an incident electromagnetic signal. The photonic detector and imaging system include a micro/nanoshell (MNS) structure that supports a surface plasmon and a rectifying junction that rectifies an evanescent electric field of the surface plasmon. The surface plasmon is excited by the incident electromagnetic signal at a plasmonic resonant absorption wavelength of the MNS structure. The method of photonic detection includes providing an MNS structure, exciting a surface plasmon on the MNS structure and rectifying an evanescent electric field of the excited surface plasmon to produce a rectified output signal. The rectified output signal provides detection of the incident electromagnetic signal. |
| US08067735B2 |
Shutterless infrared imager algorithm with drift correction
An infrared imaging system having functionality for maintaining image quality in the presence of temperature drift of the system. Such functionality is applied repetitively to maintain image quality of a target scene, yet without continuous actuation of a shutter of the system. The functionality of the imaging system results from implementing an imager algorithm. In use, the imager algorithm functions with a calibration curve created for the imaging system, with the curve comprising a plot of system output versus target scene temperature. |
| US08067732B2 |
Electron beam apparatus
An electron beam emitted from an electron gun (G) forms a reduced image on a sample (S) through a non-dispersion Wien-filter (5-1), an electromagnetic deflector (11-1), a beam separator (12-1), and a tablet lens (17-1) as an objective lens. The beam separator (12-1) is configured such that a distance by which a secondary electron beam passes through the beam separator is approximately three times longer than a distance by which a primary electron beam passes through the beam separator. Therefore, even if a magnetic field in the beam separator is set to deflect the primary electron beam by a small angle equal to or less than approximately 10 degrees, the secondary electron beam can be deflected by approximately 30 degrees, so that the primary and secondary electron beams are sufficiently separated. Also, since the primary electron beam is deflected by a small angle, less aberration occurs in the primary electron beam. Accordingly, since a light path length of a primary electro-optical system, it is possible to reduce the influence of space charge and the occurrence of deflection aberration. |
| US08067731B2 |
Chemical detection method and system
A system and method for detecting an analyte of interest in a sample is provided. The method includes passing a set of ions obtained from the sample through an ion mobility spectrometer to filter out ions that are not ions of interest and to generate an ion mobility spectrum. A mass spectrum of at least some of the ions is generated using a mass spectrometer. The method also includes determining that the analyte of interest is in the sample when peaks of interest are found in one or more of the ion mobility spectrum and the mass spectrum, and the peaks of interest follow a predetermined pattern of peaks associated with the analyte of interest or are confirmed by ion mobility spectrometry. |
| US08067730B2 |
Laser ablation electrospray ionization (LAESI) for atmospheric pressure, In vivo, and imaging mass spectrometry
The field of the invention is atmospheric pressure mass spectrometry (MS), and more specifically a process and apparatus which combine infrared laser ablation (LA) with electrospray ionization (ESI). |
| US08067728B2 |
Method of improving signal-to-noise for quantitation by mass spectrometry
Selectivity of a measurement from a mass spectrometer is improved by selecting an extracted ion current window for the measurement after data acquisition. A plurality of mass spectra are acquired over a period of time. A first extracted ion current window is selected and from the plurality of mass spectra a first intensity as a function of time is calculated for an ion using the first extracted ion current window. A second extracted ion current window is selected and from the plurality of mass spectra a second intensity as a function of time is calculated for the ion using the second extracted ion current window. A first signal-to-noise ratio of the first intensity is compared with a second signal-to-noise ratio of the second intensity. If the second signal-to-noise ratio is greater than the first signal-to-noise ratio, the second intensity as a function of time is used for the measurement. |
| US08067724B2 |
All-optical integrated photonic clock having a delay line for providing gate signal to a gate waveguide
An all-optical integrated photonic clock, systems employing the same, and methods of making and using the same. Illustrative examples are provided based on silicon semiconductor technology that employs rectangular waveguides fabricated on SOI wafers. In some embodiments, the clock can provide an optical timing signal. In some embodiments, the clock can provide a jitter-free electrical signal derived from the clock by use of a high speed photodetector. |
| US08067721B2 |
Projection-type image display apparatus having a planar reflecting element and an aspherical reflecting element with base-side positioning units integrally formed on a base
A projection-type image display apparatus includes a first reflecting optical element and a second reflecting optical element that are retained on a base. A base-side first positioning unit and a base-side second positioning unit are formed integrally with the base. The base-side first positioning unit abuts against the first reflecting optical element to define a position of the first reflecting optical element. The base-side second positioning unit abuts against the second reflecting optical element to define a position of the second reflecting optical element. |
| US08067713B2 |
Laser cutting device with high precision
An exemplary laser cutting device (300) includes a laser source (40), a lens module (51), a sprayer (60), a rotating subassembly (52), and a driving member (55). The lens module is configured for focusing a laser beam emitting from the laser source. The sprayer is rotatably connected to the lens module. The rotating subassembly is connected to the lens module. The rotating subassembly is configured for driving the lens module to rotate, such as to make the laser beam rotate relative to an axis of the laser beam. The driving member is connected to the lens and configured for driving the sprayer to rotate relative to the lens module. |
| US08067702B2 |
Electromagnetic wave shielding material and production process of the same
The production process of an electromagnetic wave shielding material of the present invention comprises screen printing a conductive paste containing conductive particles, binder and solvent in a geometrical pattern on the surface of a transparent porous layer of a transparent resin substrate provided with the transparent porous layer, the porous layer containing as a main component thereof at least one type selected from the group consisting of an oxide ceramic, a non-oxide ceramic and a metal, followed by forming a conductive portion in a geometrical pattern on the surface of the transparent porous layer by heat treatment. An electromagnetic wave shielding material produced according to this production process has high electromagnetic wave shielding effects and superior transparency and visibility. |
| US08067698B2 |
Wiring substrate for use in semiconductor apparatus, method for fabricating the same, and semiconductor apparatus using the same
On a printed-wiring board 1-1, a conductor layer 2 is laminated to both the top surface and the bottom surface of a substrate core 7 so as to pattern the substrate core, and a solder resist 4 is laminated to the substrate core. The solder resist 4 laminated to the top surface of the printed-wiring board 1-1 forms a raised portion 40 in a semiconductor chip mounting area such that the thickness of the raised portion is greater than the thickness of the solder resist 4 laminated to areas other than the semiconductor chip mounting area, so that the surface of the semiconductor chip mounting area is flat. |
| US08067695B2 |
Wiring board and method of manufacturing the same
A wiring board (package) includes: a cavity formed at a position corresponding to a chip mounting area of the outermost insulating layer on one side of both surfaces of the wiring board; a pad exposed from the surface of the insulating layer in the cavity; and a pad exposed from the surface of the insulating layer in a peripheral region of the cavity. A chip is flip-chip bonded to the pads in the cavity of the package, and another package is bonded to the pads in the peripheral region of the cavity, to thereby form a semiconductor device having a package on package (POP) structure. |
| US08067691B2 |
Covers for power distribution line insulators
A cover is provided for acute angled insulator pair arrangement, such as a V-switch. The insulator pair arrangement includes a first insulator and a second insulator, the insulators extending relative to each other at an acute angle from first ends thereof. The cover includes a first cover member and a second cover member. The second cover member is configured to mate with the first cover member to define an enclosure that encloses the first ends of the insulators and a region therebetween. The enclosure extends to a position proximate an end skirt of each of the insulators closest to the first ends thereof without extending over the end skirts. |
| US08067690B2 |
Module receptacle
A module receptacle having a main frame arranged to hold a mountable functioning module in a specified position with respect to a covering frame. The covering frame can be attached by means of at least one fastening element to the main frame. The covering frame is at least large enough to cover the main frame. |
| US08067680B2 |
Garden bean SB4372
A novel garden bean cultivar, designated SB4372, is disclosed. The invention relates to the seeds of garden bean cultivar SB4372, to the plants of garden bean line SB4372 and to methods for producing a garden bean plant by crossing the cultivar SB4372 with itself or another garden bean line. The invention further relates to methods for producing a garden bean plant containing in its genetic material one or more transgenes and to the transgenic plants produced by that method and to methods for producing other garden bean lines derived from the cultivar SB4372. |
| US08067671B2 |
Methods for genetic control of plant pest infestation and compositions thereof
The present invention is directed to controlling plant pest infestation, and particularly plant nematode infestation, by inhibiting one or more biological functions in the plant pest. The invention discloses methods and compositions for use in controlling plant pest infestation by providing one or more different recombinant double stranded RNA molecules in the diet of the pest in order to achieve a reduction in pest infestation through suppression of pest gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, to methods for detecting cells comprising the disclosed sequences, and to methods for detecting the disclosed sequences in biological samples. |
| US08067670B2 |
Plants that produce amylopectin starch with novel properties
The present invention relates to genetically modified plant cells and plants in which the genetic modification leads to a reduction in GBSSI, SSIII and BEI activity in comparison to the activity in corresponding wild type plant cells or wild type plants. Furthermore, the present invention relates to methods for the production of such plant cells and plants. The present invention also relates to the starch produced by the plant cells of the invention or plants of the invention, as well as to methods for the production of this starch and derivatised starch. |
| US08067668B2 |
Method for obtaining the pathogenic resistance in plants
The invention relates to methods for generating or increasing a pathogen resistance in plants by reducing the expression, activity or function of an NADPH oxidase. |
| US08067664B2 |
PRO224 gene disruptions, and methods related thereto
The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO224, PRO9783, PRO1108, PRO34000, PRO240, PRO943, hu A33, PRO230, PRO178, PRO1199, PRO4333, PRO1336, PRO19598, PRO1083, hu TRPM2 or PRO1801 genes. Such in vivo studies and characterizations may provide valuable identification and discovery of therapeutics and/or treatments useful in the prevention, amelioration or correction of diseases or dysfunctions associated with gene disruptions such as neurological disorders; cardiovascular, endothelial or angiogenic disorders; eye abnormalities; immunological disorders; oncological disorders; bone metabolic abnormalities or disorders; lipid metabolic disorders; or developmental abnormalities. |
| US08067659B2 |
Method of removing radioactive materials from a submerged state and/or preparing spent nuclear fuel for dry storage
A system, apparatus and method of processing and/or removing radioactive materials from a body of water that utilizes the buoyancy of the water itself to minimize the load experienced by a crane and/or other lifting equipment. In one aspect, the invention is a method comprising: a) submerging a container having a top, a bottom, and a cavity in a body of water having a surface level, the cavity filling with water; b) positioning radioactive material within the cavity of the submerged container; c) raising the submerged container until the top of the containment apparatus is above the surface level of the body of water while a major portion of the container remains below the surface level of the body of water; and d) removing bulk water from the cavity while the top of the container remains above the surface level of the body of water and a portion of the container remains submerged. The bulk water can be added back into the cavity to add neutron shielding after the container is placed in a staging area and prior to personnel performing the desired operations to the container. As a result, gamma radiation and neutron shielding of the container can be maximized for any crane capacity. |
| US08067657B2 |
Process to obtain N-paraffins from vegetable oil
The process described by this invention involves the hydroconversion of vegetable oils appropriately selected for the production of N-paraffins, through hydrotreatment of a stream of vegetable hydrocarbon oils in and/or natural fats that may be used in a pure state or in a mixture with mineral hydrocarbon oil. This mixture flow is submitted to the process of hydrotreatment, obtaining as a result, a product flow with an elevated content of N-paraffins in the range of C10-C-13. This process provides an alternative to the usual process that uses a mineral hydrocarbon oil load (petroleum kerosene of paraffin base) to produce C10-C13 N-paraffins that are raw materials for the production of detergents (LAB), being, therefore, especially advantageous for use in situations where kerosene is a limiting factor for producing N-paraffins, resulting in a product of good quality with a reasonable gain in the production of N-paraffins. |
| US08067656B2 |
Liquid-liquid separation process via coalescers
A process for separating an ionic liquid from hydrocarbons employs a coalescer material having a stronger affinity for the ionic liquid than the hydrocarbons. The coalescer material can be a high surface area material having a large amount of contact area to which ionic liquid droplets dispersed in the hydrocarbons may adhere. The process includes feeding a mixture comprising ionic liquid droplets dispersed in hydrocarbons to a coalescer comprising the coalescer material. The process further includes a capture step involving adhering at least a portion of the ionic liquid droplets to the coalescer material to provide captured droplets and a coalescing step involving coalescing captured droplets into coalesced droplets. After the capture and coalescence steps, the coalesced droplets are allowed to fall from the coalescer material to separate the ionic liquid from the hydrocarbons and provide a hydrocarbon effluent. |
| US08067655B2 |
Diisobutylene process
This invention is a process for producing diisobutylene from isobutylene. The process comprises first contacting a sulfonic acid resin with a reaction feed comprising isobutylene and tertiary butyl alcohol to produce a product stream comprising diisobutylene, isobutylene, tertiary butyl alcohol, and water. The product stream is distilled to produce a first overhead stream comprising water and isobutylene and a first bottoms stream comprising diisobutylene and tertiary butyl alcohol. Water is separated from the first overhead stream, and the resulting isobutylene-enriched stream is recycled back to the reaction step. The first bottoms stream is distilled to produce a second overhead stream comprising tertiary butyl alcohol and a bottoms product stream comprising diisobutylene. |
| US08067646B2 |
Combined temperature controlled adsorption and heat pump process for fuel ethanol dehydration
Systems and processes for dehydration of a process stream in the production of motor fuel grade ethanol (MFGE) can include temperature controlled adsorption of water in the process stream, and heat pumping of the associated heat of adsorption. The process can include providing a process stream (110) including ethanol and water to a first temperature controlled adsorber (102) where water is removed by adsorption to produce an MFGE product stream (114) and an associated heat of adsorption. A cooling fluid can be provided to the first temperature controlled adsorber (102) to remove heat of adsorption and produce a heated cooling fluid (120). Heat from the heated cooling fluid can be provided to a heat sink. |
| US08067640B2 |
Method for the separation of intermediates which may be used for the preparation of escitalopram
The present invention relates to a novel method for the preparation of diol intermediates having the formula (II) and/or the opposite enantiomer of an acylated diol having the formula (IV) useful for the preparation of escitalopram involving selective enzymatic acylation or deacylation. |
| US08067638B2 |
Amide derivative and insecticide containing the same
The present invention is to provide a compound represented by the general formula (1) exhibiting a high insecticidal effect and an insecticide comprising the compound as an active ingredient. The compound represented by the general formula (1) and an insecticide comprising the compound as an active ingredient, wherein, in the formula, A1, A2, A3 and A4 each represent a carbon atom or the like; R1 and R2 each represent a hydrogen atom or the like; G1 and G2 represent an oxygen atom or the like; Xs each represent a hydrogen atom, a halogen atom or the like; n represents an integer of 0 to 4; Q1 represents a substituted phenyl group, a substituted heterocyclic group or the like; Q2 represents a substituted phenyl group, a substituted heterocyclic group or the like. |
| US08067635B2 |
Method for producing tertiary amides of alkylphenyl carboxylic acids
The invention relates to a method for producing tertiary amides of alkylphenyl carboxylic acids by reacting at least one secondary amine with at least one alkylphenyl carboxylic acid to form an ammonium salt, said ammonium salt being subsequently converted into the tertiary amide by means of microwave radiation. |
| US08067634B2 |
Process for producing allyl acetate
A process for producing allyl acetate is disclosed. The process comprises reacting propylene, acetic acid, and oxygen in the presence of a supported palladium catalyst in an adiabatic reactor. |
| US08067632B2 |
Process to produce prostratin and structural or functional analogs thereof
This invention concerns a process to convert a hydroxyl group (bold in R3C—OH) in a tigliane-type compound to a hydrogen (bold in R3C—H) to obtain deoxytigliane-type compounds or structural or functional analogs thereof. The process has wide application particularly to produce specific biologically active compounds in quantity for use as pharmaceuticals. In particular the process can be used to convert phorbol to a 12-deoxytigliane (prostrating which is a therapeutic lead for the treatment of AIDS. New compositions of matter are also disclosed. |
| US08067631B2 |
Method of rapid methylation of alkene compound and kit for PET tracer preparation using the same
To provide a method of rapid methylation of alkenes, which is applicable to the preparation of a PET tracer and which enables alkenes to be methylated through cross coupling between SP2 (alkenyl) and SP3 (alkyl) carbon atoms rapidly and in a high yield. Methyl iodide and an alkenyltrialkylstannane are subjected to cross coupling in an aprotic polar solvent in the presence of a palladium complex having a valence of 0, a phosphine ligand, a cuprous halide, and a carbonate and/or alkali metal fluoride. |
| US08067627B2 |
Zinc-monocysteine complex and method of using zinc-cysteine complexes
A method of providing zinc to a subject in need of treatment includes administering to the subject an effective amount of a zinc-cysteine complex. The zinc-cysteine complex is preferably a zinc-monocysteine complex. The complexes of zinc-cysteine of the present invention increase the activity of antioxidant enzymes catalase and glutathione peroxidase, and the antioxidant protein metallothionein. The complexes of zinc-cysteine of the present invention protect retinal pigment epithelial cells from increasing hydrogen peroxide concentrations. |
| US08067622B2 |
Method for producing naringenin derivatives from xanthohumol
The present invention relates to an efficient method for producing naringenin derivatives from xanthohumol or derivatives thereof. In particular, the method according to the present invention provides the production of isoxanthohumol, for example also in enantiomer-enriched form, from xanthohumol and subsequent demethylation of isoxanthohumol according to specific procedures obtaining corresponding naringenin derivatives, such as, in particular, 8-prenylnaringenin. |
| US08067619B2 |
Coumarin derivatives as ion channel openers
The present invention is directed to coumarin derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders related to ion channels such as potassium channels. |
| US08067615B2 |
Sulphonylpyrroles
Compounds of a certain formula (I), in which R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in the description, are novel effective HDAC inhibitors. |
| US08067614B2 |
N-substituted (benzoimidazol-2-yl)phenylamines, processes for their preparation, their use as a medicament or diagnostic aid, and a medicament comprising them
This invention is directed to the compound of formula (I), compositions containing said compounds to inhibit the sodium-proton exchanger of subtype 3 (NHE3) which are useful in the prevention or treatment of various disorders in a patient suffering from a disease state, such as, renal disorders including acute or chronic renal failure, disorders of biliary function and for respiratory disorders such as snoring or sleep apnea or for stroke. |
| US08067613B2 |
Benzimidazole poly(ADP ribose)polymerase inhibitors
Compounds which inhibit the activity of poly(ADP-ribose)polymerase (PARP), compositions containing the compounds and methods of treating diseases using them are disclosed. |
| US08067610B2 |
Synthesis of terminal alkenes from internal alkenes and ethylene via olefin metathesis
This invention relates generally to olefin metathesis, and more particularly relates to the synthesis of terminal alkenes from internal alkenes using a cross-metathesis reaction catalyzed by a selected olefin metathesis catalyst. In one embodiment of the invention, for example, a method is provided for synthesizing a terminal olefin, the method comprising contacting an olefinic substrate comprised of at least one internal olefin with ethylene, in the presence of a metathesis catalyst, wherein the catalyst is present in an amount that is less than about 1000 ppm relative to the olefinic substrate, and wherein the metathesis catalyst has the structure of formula (II) wherein the various substituents are as defined herein. The invention has utility, for example, in the fields of catalysis, organic synthesis, and industrial chemistry. |
| US08067607B2 |
Potassium channel inhibitors
The present invention relates to pyridin-3-yl pyridin-3-amine compounds and derivatives thereof having the structure formula (I) useful as potassium channel inhibitors to treat cardiac arrhythmias, and the like. |
| US08067606B2 |
Gyrase inhibitors and uses thereof
The present invention relates to methods of treating, preventing, or lessening the severity of resistant bacterial infections in mammals, utilizing compounds of formula I or formula VII or pharmaceutically salts thereof. The present invention also relates to methods of using compounds of formula I or formula VII in combination with one or more additional antibacterial agents and/or one or more additional therapeutic agents that increase the susceptibility of bacterial organisms to antibiotics. |
| US08067603B2 |
Benzimidazolone and quinazolinone derivatives as agonists on human ORL1 receptors
The invention relates to a group of novel benzimidazolone and quinazolinone derivatives which are agonists on human ORL1 (nociceptin) receptors. The invention also relates to the preparation of these compounds, to pharmaceutical compositions containing a pharmacologically active amount of at least one of these imidazolone and quinazolinone derivatives as an active ingredient, as well as to the use of these pharmaceutical compositions for the treatment of disorders in which ORL1 receptors are involved. The invention relates to compounds of the general formula (1): wherein the symbols have the meanings as given in the description. |
| US08067592B2 |
N-alkyny-2-(substituted aryloxy) alkylthioamine derivatives as fungicides
Fungicidal compounds of the general formula (1), wherein Ar is a group of the formula (A), (B1), (B2) or (C), or Ar is a 5- or 6-linked group of the formula (D1) or (D2); and R1, R2, R3, R4, R5, n, A1, A2, A3, A4, A5, Ka, Kb, L, M, V, W, X, Y and Z have the definitions given in claim 1. |
| US08067591B2 |
Pyrrolopyrazole, potent kinase inhibitors
Pyrrole pyrazole compounds of formula I, compositions including these compounds and methods of their use are provided. Preferred compounds of formula I have activity as protein kinase inhibitors, including as inhibitors of PAK4. |
| US08067585B2 |
Method for producing disulfonyl fluoride compound
The present invention relates to producing a disulfonyl fluoride compound easily and efficiently by utilizing coupling reaction where a compound (2) is obtained by subjecting a compound (1) wherein Y is a fluorine atom to photocoupling reaction, or subjecting a compound (1) wherein Y is a hydroxyl group, —OMa wherein Ma is an alkali metal atom, or —O(Mb)1/2 wherein Mb is an alkaline earth metal atom to electrolytic coupling reaction, and derivatives such as the following compound (7A) are obtained from the compound (2): FSO2-E-CX2—COY (1) FSO2-E-CX2—CX2-E-SO2F (2) wherein E is a single bond, —O—, a C1-20 alkylene group which may contain an etheric oxygen atom, or the like, X is a fluorine atom or the like, and Y is a fluorine atom, a hydroxyl group, or the like. |
| US08067584B2 |
Benzothiazepine derivatives
Compounds of formula: (1) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as ileal bile acid transport (IBAT) inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described. |
| US08067581B2 |
Biomolecules having multiple attachment moieties for binding to a substrate surface
Compounds relating to attachment chemistries for binding biomolecules to a substrate surface are described. These include compounds of the following structure: The biomolecule includes a single nucleic acid, oligonucleotides, polynucleotides, DNAs, RNAs, proteins, peptides, enzymes, antibodies, CNAs (cyclohexyl nucleic acids), p-MeNAs (methyl or methoxy phosphate nucleic acids), peptide nucleic acids (PNAs), and pyranosyl RNAs (p-RNAs). |
| US08067578B2 |
Substrate preparation process
The present invention provides novel processes for the large scale preparation of arrays of polymer sequences wherein each array includes a plurality of different, positionally distinct polymer sequences having known monomer sequences. The methods of the invention combine high throughput process steps with high resolution photolithographic techniques in the manufacture of polymer arrays. |
| US08067576B2 |
siRNA targeting serine/threonine kinase 12 (STK12 or aurora B kinase)
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to STK12. |
| US08067573B2 |
Nucleic acid agents for downregulating H19 and methods of using same
The present invention provides isolated oligonucleotides capable of down-regulating a level of H19 mRNA in cancer cells. Articles of manufacture comprising agents capable of downregulating H19 mRNA in combination with an additional anti-cancer treatment are disclosed as well as methods of treating cancer by administering same. |
| US08067572B2 |
Hybrid interfering RNA
The invention relates to a hybrid interfering RNA molecule comprising a duplex RNA and a single stranded DNA molecule and its use in the ablation of mRNA and in polymerase chain reactions. |
| US08067571B2 |
Antibacterial antisense oligonucleotide and method
A method for enhancing, by at least 10 fold, the antibacterial activity of an antisense oligonucleotide composed of morpholino subunits linked by phosphorus-containing intersubunit linkages. The method includes one or both of: conjugating an arginine-rich carrier to a 3′ or 5′ end of the oligonucleotide and modifying the oligonucleotide to contain 20%-50% intersubunit linkages that are positively charged at physiological pH. Also disclosed is an antisense oligonucleotide having enhanced antibacterial activity by virtue of one or both modifications. |
| US08067569B2 |
Splice-region antisense composition and method
Antisense compositions targeted against an mRNA sequence coding for a selected protein, at a region having its 5′ end from 1 to about 25 base pairs downstream of a normal splice acceptor junction in the preprocessed mRNA, are disclosed. The antisense compound is RNase-inactive, and is a phosphorodiamidate-linked morpholino oligonucleotide containing uncharged phosphorodiamidate linkages interspersed with cationic phosphorodiamidate linkages. Such targeting is effective to inhibit natural mRNA splice processing, produce splice variant mRNAs, and inhibit normal expression of the protein. |
| US08067567B2 |
Modified tert promoter with enhanced tumor-specificity and strength and recombinant vector comprising the same
The present invention relates to a transcriptional regulatory sequence with enhanced tumor-specificity and strength and a recombinant vector comprising the transcriptional regulatory sequence. More particularly, the present invention relates to a transcriptional regulatory sequence comprising a human telomere reverse transcriptase (hTERT) promoter linked to a nucleotide sequence that comprises one or more c-Myc binding sites and/or one or more Sp1 binding sites, and a recombinant vector comprising a certain gene that is operably linked to the above transcriptional regulatory sequence. |
| US08067565B2 |
Dengue serotype 1 attenuated strain
The invention relates to live attenuated VDV1 (VERO-Derived Dengue serotype 1 virus) strains which have been derived from the wild-type dengue-1 strain 16007 by passaging on PDK and sanitization on Vero cells and nucleic acids thereof. The invention further relates to a vaccine composition which comprises a VDV1 strain. |
| US08067562B2 |
Isolated nucleic acid molecule comprising the amino acid sequence of SEQ ID NO:1
The present invention provides novel activin IIB5 receptor polypeptides capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the receptor polypeptides. Compositions and methods for treating muscle-wasting, metabolic and other disorders are also provided. |
| US08067556B2 |
Multi-site mutagenesis
The present invention provides compositions and improved methods for multi-site directed mutagenesis and DNA shuffling. The present compositions and methods provide increased mutation frequency and increased number of transformants which allow one to sequence only a few clones in order to identify the correct mutants and to obtain the desired mutant by screening large number of transformants in a short time. Moreover, the inclusion of FEN-1, PEF and optimized buffer and cycling conditions provided in the present invention should also facilitate random mutagenized library construction and the mutagenesis of large or difficult templates. |
| US08067553B2 |
PEG-urate oxidase conjugates and use thereof
A naturally occurring or recombinant urate oxidase (uricase) covalently coupled to poly(ethylene glycol) or poly(ethylene oxide) (both referred to as PEG), wherein an average of 2 to 10 strands of PEG are conjugated to each uricase subunit and the PEG has an average molecular weight between about 5 kDa and 100 kDa. The resulting PEG-uricase conjugates are substantially non-immunogenic and retain at least 75% of the uricolytic activity of the unmodified enzyme. |
| US08067551B2 |
Combinatorial DNA library for producing modified N-glycans in lower eukaryotes
The present invention relates to eukaryotic host cells having modified oligosaccharides which may be modified further by heterologous expression of a set of glycosyltransferases, sugar transporters and mannosidases to become host-strains for the production of mammalian, e.g., human therapeutic glycoproteins. The invention provides nucleic acid molecules and combinatorial libraries which can be used to successfully target and express mammalian enzymatic activities such as those involved in glycosylation to intracellular compartments in a eukaryotic host cell. The process provides an engineered host cell which can be used to express and target any desirable gene(s) involved in glycosylation. Host cells with modified oligosaccharides are created or selected. N-glycans made in the engineered host cells have a Man5GlcNAc2 core structure which may then be modified further by heterologous expression of one or more enzymes, e.g., glycosyltransferases, sugar transporters and mannosidases, to yield human-like glycoproteins. For the production of therapeutic proteins, this method may be adapted to engineer cell lines in which any desired glycosylation structure may be obtained. |
| US08067550B2 |
Hybridomas producing antibodies against non functional P2X7 receptor
The present invention relates to the production of anti non functional P2X7 receptor monoclonal antibodies from hybridoma cell lines. |
| US08067547B2 |
Stable and soluble antibodies inhibiting TNFα
The present invention relates to particularly stable and soluble scFv antibodies and Fab fragments specific for TNFα, which comprise specific light chain and heavy chain sequences that are optimized for stability, solubility, in vitro and in vivo binding of TNFα, and low immunogenicity. Said antibodies are designed for the diagnosis and/or treatment of TNFα-related disorders. The nucleic acids, vectors and host cells for expression of the recombinant antibodies of the invention, methods for isolating them and the use of said antibodies in medicine are also disclosed. |
| US08067542B1 |
Amino acid sequence variant alfalfa antifungal protein and its use in plant disease control
The present invention relates to an antifungal protein, AlfAFP1, which is a modified form of an antifungal protein isolated from Medicago plants, the modified form exhibiting enhanced anti-fungal activity for controlling fungal pathogenesis in plants. A method for inhibiting fungal colonization of plants is described which includes preparation of nucleotide sequences encoding the modified antifungal protein, preparation of vectors containing the nucleotide coding sequence, and methods for transforming plants with the nucleotide sequences. The polypeptide can be formulated into compositions useful in controlling plant pathogenic fungi. |
| US08067540B2 |
Human ALEX1 proteins
The present invention provides a novel protein containing an armadillo repeat, a gene encoding this protein, and production and use thereof. The present inventors identified a gene named ALEX1 encoding a human-derived novel armadillo repeat-containing protein. It was clarified that ALEX1 interacts with several proteins including insulin-degrading enzyme, presenilin-1, and JNK interacting protein 1. This gene shows significantly decreased expression in cancer cells. The protein ALEX1 and the gene encoding this protein are usable as tools in testing for diseases such as cancer and Alzheimer's disease and developing pharmaceutical agents. |
| US08067538B2 |
Gene related to growth promoting function of acetic acid bacterium, acetic acid bacterium bred using the gene and method for producing vinegar using the acetic acid bacterium
The present invention is to obtain a novel gene that encodes a protein having a function of promoting acetic acid bacterial growth in the presence of a high concentration of acetic acid; to enhance acetic acid bacteria's function of promoting growth and thereby to develop acetic acid bacteria with an improved fermentation ability in the presence of a high concentration of acetic acid; and to provide a method for efficiently producing vinegar that contains a high concentration of acetic acid in a short time using the acetic acid bacterium. A novel gene having a function of improving the function of promoting growth at a practical level was cloned from acetic acid bacteria for practical use, belonging to the genus Gluconacetobacter, by a method comprising exposing acetic acid bacterial lysate to the presence of a high concentration of acetic acid; obtaining a gene of a protein that was not insolubilized but remained soluble; and thereby obtaining a gene having a function of promoting acetic acid bacterial growth in the presence of acetic acid. When cultured in the presence of acetic acid and ethanol, a transformant of acetic acid bacteria transformed with the gene was confirmed to have a significant effect of promoting growth. |
| US08067535B2 |
Identification of gene sequences and proteins involved in vaccinia virus dominant T cell epitopes
The present invention relates to the identification of gene sequences and proteins involved in vaccinia virus dominant T cell epitopes. Three vaccinia virus CD8+ T cell epitopes restricted by the most common human M.C. class I allele, HLA-A0201, were identified. Each of these epitopes is highly conserved in vaccinia and variola viruses. In addition, the induction of the T cell responses following primary vaccination with two of these epitopes is demonstrated by the kinetics of epitope specific CD8+ T cells in 3 HLA-A0201 individuals. Two vaccinia virus CD8+ T cell epitopes restricted by another common human M.C. class I allele, HLA-B7, also were identified. Both epitopes are highly conserved in vaccinia and variola viruses. This information will be useful for the design and analysis of the immunogenicity of experimental vaccinia vaccines, and for basic studies of human T cell memory. |
| US08067530B2 |
Scytovirin domain 1 related polypeptides
A scytovirin domain 1 (SD1) polypeptide, a nucleic acid encoding the polypeptide, and related fusion proteins, conjugates, isolated cells, vectors, and antibodies, as well as a method of inhibiting a viral infection using the same. |
| US08067526B2 |
Method for producing polyoxalkylene derivative
A method for producing a polyoxyalkylene derivative including: step (A) in which a polyoxyalkylene derivative having hydroxyl group(s) is reacted with a phthalimide derivative in the presence of an azo reagent and a phosphine reagent; step (B) in which the phthalimide groups of the compound obtained in step (A) are deprotected using a compound having a primary amino group; and step (C) in which impurities derived from the phthalimide derivative and the deprotection reagent are removed by adsorption or extraction. |
| US08067525B2 |
Film(s) and/or sheet(s) comprising polyester compositions which comprise cyclobutanediol and have a certain combination of inherent viscosity and high glass transition temperature
Described are film(s) and/or sheet(s) comprising polyesters comprising (a) a dicarboxylic acid component having terephthalic acid residues; optionally, aromatic dicarboxylic acid or aliphatic dicarboxylic acid residues; 2,2,4,4-tetramethyl-1,3-cyclobutanediol residues; and 1,4-cyclohexanedimethanol residues. |
| US08067520B2 |
Curable composition
It is an object of the present invention to provide a two-component curable composition whose component A is easy to be handled, and which shows excellent internal curability and good storage stability. This problem is solved using a two-component curable composition, comprising component A comprising 100 parts by weight of an organic polymer containing a reactive silicon group, (B) 0.1-300 parts by weight of an epoxy group-containing compound, and (C) 0.1-20 parts by weight of water, and component B comprising (D) 0.1-20 parts by weight of a curing catalyst, and (E) 0.1-200 parts by weight of an amine compound. |
| US08067518B2 |
Polymers made with metallocene catalysts, for use in rotomolding and injection molding products
Ethylene alpha-olefin copolymers formed by contacting at least one supported metallocene catalyst, ethylene, and an alpha-olefin in a gas phase reactor are disclosed. In some embodiments, the polymer may have: a density of between 0.890 and 0.970 g/cc; a melt index of between 0.7 and 200 dg/min; a melt index ratio of less than 30; an ESCR value of greater than 1000 hours; and a 1% secant modulus of greater than 75,000 psi. In other embodiments, the polymer may have: a density of between 0.930 g/cc and 0.970 g/cc; a melt index of between 10 dg/min and 200 dg/min; a melt index ratio of between 10 and 25; a part weight of greater than 3 g and a part length of greater than 38 cm in a spiral flow test, and; a zero shear viscosity of less than 150 Pa·s. Processes to produce these polymers are also disclosed. |
| US08067514B2 |
Anisotropic conductive film
An anisotropic conductive film is provided which can provide high bonding strength and good conduction reliability when anisotropic conductive bonding is made under the compression bonding conditions of a compression bonding temperature of at most 130° C. for a compression bonding time of at most 3 seconds. The anisotropic conductive film contains a polymerizable acrylic compound, a film-forming rein, conductive particles, and a polymerization initiator. The polymerization initiator contains two types of organic peroxides that do not produce oxygen gas resulting from the decomposition thereof and have different one-minute half-life temperatures. Of the two types of organic peroxides, one organic peroxide that has a higher one-minute half-life temperature produces benzoic acid or a derivative thereof when it decomposes. |
| US08067512B2 |
Monomer/solvent separation and recycle process for propylene containing polymers
Monomer/solvent separation and recycle processes for continuous supercritical, solution and advanced solution polymerization processes for propylene-containing polymers and their blends are provided. The advantageous monomer/solvent separation and recycle process includes heating a polymer-lean recycle stream coming from a gravimetric separator positioned downstream of the reactor to form a heated polymer-lean recycle stream, and subsequently combining the heated polymer-lean recycle stream with the one or more homogenous reactor effluent streams to form a heated reactor effluent mixed stream. The heated reactor effluent mixed stream may then be passed through a pressure let-down valve followed and a gravimetric separator, such as to provide for reduced fouling propensity of the polymer-rich phase and sufficient heating of the polymer-rich phase to be able to pass through the remainder of the processing steps to form a propylene based polymer product without additional heat. |
| US08067507B2 |
Compositions for preventing or reducing aluminosilicate scale in industrial processes
Materials and a method are provided whereby polymers with least 0.5 mole % of the pendant group or end group containing —Si(OR″)3 (where R″ is H, an alkyl group, Na, K, or NH4) are used to control aluminosilicate scaling in an industrial process having an alkaline process stream such as a pulping mill process stream. When materials of the present invention are added to the alkaline process stream, they reduce and even completely prevent formation of aluminosilicate scale on equipment surfaces such as evaporator walls and heating surfaces. The present materials are effective at treatment concentrations that make them economically practical. |
| US08067506B2 |
Water-soluble fluorescent particle comprising entangled fluorescent polymer and amphiphilic molecule
Water-soluble fluorescent particles are formed in a simple process. A mixture comprising a solvent, water, a fluorescent polymer dissolved in the solvent, and an amphiphilic molecule is provided. The fluorescent polymer comprises a hydrophobic segment. The amphiphilic molecule comprises hydrophilic and hydrophobic segments. The solvent is removed from the mixture to allow the fluorescent polymer and the amphiphilic molecule to entangle in the presence of water, thus forming the water-soluble fluorescent particles. In the formed particles, the hydrophilic segments of the amphiphilic molecule are entangled with one another, and the hydrophobic segments of the fluorescent polymer and amphiphilic molecule are entangled with one another. The amphiphilic molecule encapsulates the fluorescent polymer and at least some of the hydrophilic segments are exposed to render the particle soluble in water. |
| US08067499B2 |
Thermoplastic resin composition, a solar cell sealing sheet, and a solar cell
The present invention provides a thermoplastic resin composition that gives a solar cell sealing sheet having, even without being crosslinked, good mechanical strength, solar cell sealability, transparency, and weatherability.The thermoplastic resin composition of the present invention comprises 1 to 95% by weight of a propylene-based polymer (A) and 5 to 99% by weight of a copolymer (B) with at least one •-olefin having 2 to 20 carbon atoms other than propylene, wherein (A) satisfies the following (i) and (ii), and (B) has a melting point below 80° C. or does not show a melting point as measured by a differential scanning calorimeter (DSC). (i) Melting point measured by a differential scanning calorimeter (DSC) method is in the range of 80 to 135° C. (ii) Endotherm attributable to crystal melting is not observed at 140° C. or more in the endothermic curve measured by a differential scanning calorimeter (DSC) method. |
| US08067495B2 |
Thermoplastic elastomer composition and glass panel molding assembly for a vehicle
The present invention relates to a thermoplastic elastomer composition and a glass panel molding assembly for a vehicle. The thermoplastic elastomer composition comprising a polymer component (1) that comprises a styrene-type thermoplastic elastomer and a polyolefin-type polymer {except for the additives in item (5) below}, a non-aromatic-rubber softener (2), a higher fatty acid derivative (4), and at least one type of an additive (5) selected from (5-a) a vinyl polymer graft-olefin polymer, (5-b) a polyorganosiloxane cross-linked powder; and (5-c) a polyorganosiloxane graft-olefin polymer. And the glass panel molding assembly for a vehicle produced from the aforementioned composition. |
| US08067485B2 |
Masterbatch and polymer composition
The present invention relates to a method of preparing a biodegradable polymer composition, said method comprising melt mixing a first biodegradable polyester and a masterbatch, wherein said masterbatch has been formed separately by melt mixing in the presence of a transesterification catalyst a polysaccharide, a second biodegradable polyester and a biodegradable polymer having pendant carboxylic acid groups. |
| US08067481B2 |
Low shrinkage dental material and method
The invention provides a low polymerization shrinkage dental composition and a polymerizable dental material selected from the group consisting of wax-like dental material that undergoes ring open polymerization. The dental composition is useful as restorative material and for making artificial teeth, dentures, restoratives, crowns and bridges of high strength dental polymeric material. |
| US08067477B2 |
Resin composition for electrophotographic toners and electrophotographic toners
An object of the present invention is to provide the resin composition for electro-photographic toner, which the electro-photographic toner to be obtained by it is superior to low temperature fixing properties and a hot offset resistance, and the electro-photographic toner thereof. To be achieved this purpose, multi-branched state polyester structure having a structure representing the following structural formula (1) as a repeating unit, is made into a main skeleton (In the formula, R expresses an aliphatic hydrocarbon group, and n shows the number of repeating units of a branched structure and is an average of 1-5.) *a is a node of the carbon atom of a carbonyl group, *b is a node of an oxygen atom, and *b is bonded to *a in the other repeating unit of the structural formula (1)). In addition, polyester resin (A) having a ratio of 25 to 95% of the weight for alkyl group of the number of carbon atoms 20-80 or alkenyl group of the number of carbon atoms 20-80 to the molecular terminal and aliphatic series crystalline polyester resin (B) is contained. The electro-photographic toner containing the resin composition for electro-photographic toner and this composition is provided. |
| US08067474B2 |
Process for the preparationn of hydrocarbons from oxygenates
A process for the preparation of hydrocarbon products comprising the steps of a) providing a synthesis gas comprising hydrogen, carbon monoxide and carbon dioxide; (b) reacting at least part of the synthesis gas to an oxygenate mixture comprising methanol and dimethyl ether in presence of one or more catalysts which together catalyse a reaction of hydrogen and carbon monoxide to oxygenates at a pressure of at least 3 MPa; (c) withdrawing from step (b) a reaction mixture comprising amounts of methanol, dimethyl ether, carbon dioxide and water together with unreacted synthesis gas and cooling the reaction mixture to obtain a liquid phase with the amounts of methanol, dimethyl ether and water and simultaneously dissolving carbon dioxide in the liquid phase; (d) separating the carbon dioxide containing liquid phase from a remaining gaseous phase comprising hydrogen and carbon monoxide; (e) evaporating and reacting the liquid phase being withdrawn from step (d) in presence of a catalyst being active in the conversion of oxygenates to higher hydrocarbons and a tail gas comprising carbon dioxide; (f) separating tail gas from a liquid phase with the higher hydrocarbons; and wherein pressure employed in step (c) to step (f) is substantially the same as employed in step (b). |
| US08067470B2 |
Linoleic acid preparations for the topical treatment of male and female pattern androgenetic alopecia, age-related alopecia, and keratosis pilaris
A preparation for the topical application of linoleic acid to treat male and female androgenetic alopecia, age-related alopecia, and keratosis pilaris contains between about 0.1% and about 10%, preferably between about 1% and about 5%, and specifically about 2% linoleic acid by volume in its carrier vehicle. This acts to correct the local linoleic acid deficiency that exists in the follicles in these conditions and provides linoleic acid to suppress growth of Propionibacterium acnes with resultant reduction in its porphyrin production which in turn reduces microinflammation and altered keratinization that damages follicles and eliminates functioning follicles in alopecia and causes follicle plugging in keratosis pilaris. |
| US08067469B2 |
System for trapping flying insects with attractant lures
The present application discloses a system for trapping flying insects, a first chemical lure such as lactic acid, a salt of lactic acid, or combinations thereof, and a second chemical lure comprising a source of ammonia. The lures may be employed in particular geometric shapes contained in specifically designed housing to ensure an effective release rate over extended periods of time. |
| US08067468B2 |
L-carnitine and alkanoyl L-carnitine phytates and process for preparing the same
Salts of L-carnitine and alkanoyl L-carnitines with phytic acid of general formula (I), and the process of preparing the same, wherein the mole ratio between the L-carnitine or its alkanoyl derivatives cation and phytic acid anion be within the range of 1:1 to 6:1, wherein: n=1-6; R1 is the phytate anion; R is either hydrogen, a straight alkanoyl group having 2-12 carbon atoms or a branched-chain alkanoyl group having 2-12 carbon atoms. |
| US08067466B2 |
Cycloalkyl-hydroxyl compounds and compositions for cholesterol management
The present invention relates to novel cycloalkyl-hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer's Disease, cancer, cardiovascular disease, diabetic nephropathy, diabetic retinopathy, a disorder of glucose metabolism, dyslipidemia, dyslipoproteinemia, hypertension, impotence, inflammation, insulin resistance, lipid elimination in bile, obesity, oxysterol elimination in bile, pancreatitis, Parkinson's disease, a peroxisome proliferator activated receptor-associated disorder, phospholipid elimination in bile, renal disease, septicemia, Syndrome X, thrombotic disorder. Compounds and methods of the invention can also be used to modulate C reactive protein or enhance bile production in a patient. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents. |
| US08067458B2 |
Alkoxyalkyl-substituted cyclic ketoenols
The invention relates to new alkoxyalkyl-substituted cyclic ketoenols of the formula (I) in which A, B, D, G, W, X and Y have the definitions indicated above, to processes and intermediates for their preparation, and to their use as pesticides and/or microbicides and/or herbicides. The invention further provides selectively herbicidal compositions which comprise alkoxyalkyl-substituted cyclic ketoenols on the one hand and a crop plant tolerance promoter compound on the other. The invention further relates to the boosting of the action of crop protection compositions comprising compounds of the formula (I) through the additions of ammonium salts or phosphonium salts and optionally penetration promoters. |
| US08067451B2 |
Methods and medicaments for administration of ibuprofen
A method for administration of ibuprofen to a subject in need of ibuprofen treatment is provided, in which an oral dosage form comprising a therapeutically effective amount of ibuprofen and a therapeutically effective amount of famotidine is administered three times per day. |
| US08067448B2 |
Selective androgen receptor modulators
This invention provides compounds of formulas I, Ia, Ib, Ic, Id, Ie, and or salts thereof, pharmaceutical compositions comprising a compound of formulas I, Ia, Ib, Ic, Id, Ie, and a pharmaceutically acceptable excipient, methods of modulating the androgen receptor, methods of treating diseases beneficially treated by an androgen receptor modulator (e.g., sarcopenia, prostate cancer, contraception, type 2 diabetes related disorders or diseases, anemia, depression, and renal disease) and processes for making compounds of formulas I, Ia, Ib, Ic, Id, Ie, and intermediates useful in the preparation of same. |
| US08067447B2 |
Modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
Novel non-steroidal compounds are provided which are useful in treating diseases associated with modulation of the glucocorticoid receptor, and/or AP-1, and/or NF-κB activity including inflammatory and immune diseases, obesity and diabetes having the structure of formula (I), its enantiomers, diastereomers, or a pharmaceutically-acceptable salt, or hydrate, thereof, wherein (Ia) is heterocycle or heteroaryl; J, Ja, E, F, G, Ma, M, Q, Za and Z are as defined herein. Also provided are pharmaceutical compositions and methods of treating inflammatory- or immune-associated diseases and obesity and diabetes employing said compounds. |
| US08067439B2 |
Biphenyl compounds useful as muscarinic receptor antagonists
This invention provides compounds of formula I: wherein a, b, c, d, m, n, p, r, R1, R2, R3, R4, R5, R6, R7, and W are as defined in the specification. The compounds of formula I are muscarinic receptor antagonists. The invention also provides pharmaceutical compositions containing such compounds, processes and intermediates for preparing such compounds and methods of using such compounds to treat pulmonary disorders. |
| US08067437B2 |
Beta-2-adrenoreceptor agonists
Compounds of formula in free or salt or solvate form, where Ar is a group of formula Y is carbon or nitrogen and R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n, p, q and r are as defined in the specification, their preparation and their use as pharmaceuticals, particularly for the treatment of obstructive or inflammatory airways diseases. |
| US08067435B2 |
Nitrogen-containing heterocyclic compounds, their preparation and their use as antibacterial drugs
The invention relates to nitrogen-containing heterocyclic compounds of general formula (I) wherein: R1 represents a (CH2)n—NH2 radical, n being equal to 1 or 2; R2 represents a hydrogen atom; R3 and R4 form together a nitrogen-containing heterocycle with aromaticity with 5 apices containing 1, 2 or 3 nitrogen atoms, substituted on this nitrogen atom or one of these nitrogen atoms with a (CH2)m—(C(O))p—R5 group, m being equal to 0, 1, 2 or 3, p being equal to 0 or 1 and R5 representing a hydroxy group, in which case p is equal to 1, or an amino, (C1-C6)alkyl or di-(C1-C6)alkyl amino, a nitrogen-containing heterocycle with aromaticity with 5 or 6 apices containing 1 or 2 nitrogen atoms and if necessary, an oxygen or sulfur atom; it being understood that when the sub-group (C(O))p—R5 forms a carboxy, amino, (C1-C6) alkyl or di-(C1-C6) alkyl amino, group, m is different from 0 or 1; in free form or as zwitterions and salts with pharmaceutically acceptable mineral or organic bases and acids, to their preparation and to their use as antibacterial drugs. |
| US08067430B1 |
Anti-HIV activity of the opioid antagonist naloxone
A method of treating HIV infection by using the novel anti-HIV activity of the opioid antagonist naloxone. |
| US08067428B2 |
Platelet ADP receptor inhibitors
Novel compounds of formulae (I) to (VIII), which more particularly include sulfonylurea derivatives, sulfonylthiourea derivatives, sulfonylguanidine derivatives, sulfonylcyanoguanidine derivatives, thioacylsulfonamide derivatives, and acylsulfonamide derivatives which are effective platelet ADP receptor inhibitors. These derivatives may be used in various pharmaceutical compositions, and are particularly effective for the prevention and/or treatment of cardiovascular diseases, particularly those diseases related to thrombosis. The invention also relates to a method for preventing or treating thrombosis in a mammal comprising the step of administering a therapeutically effective amount of a compound of formulae (I) to (VIII), or a pharmaceutically acceptable salt thereof. |
| US08067426B2 |
6-amino-purin-8-one compounds
Compounds of formula (I): wherein R1 is C1-6alkylamino, C1-6alkoxy, or C3-7cycloalkyloxy; m is an integer having a value of 3 to 6; n is an integer having a value of 0 to 4; and salts thereof are inducers of human interferon. Compounds which induce human interferon may be useful in the treatment of various disorders, for example the treatment of allergic diseases and other inflammatory conditions for example allergic rhinitis and asthma, the treatment of infectious diseases and cancer, and may also be useful as vaccine adjuvants. |
| US08067425B2 |
Neuroprotective bicyclic compounds and methods for their use
Embodiments of this invention provide novel cyclic compounds structurally related to diketopiperazines and methods for their therapeutic use. Such compounds are neuroprotective and have utility as therapeutic agents for treatment of diseases, injuries and other conditions characterized by neuronal degeneration and/or death. Compounds are also useful for manufacture of medicaments useful for treatment of such conditions. |
| US08067424B2 |
Selective inhibitors for cyclin-dependent kinases
This invention provides a class of compounds which are useful for specifically inhibiting cyclin-dependent kinases. This class of compounds finds use in treating diseases resulting from inappropriate activity of cyclin-dependent kinases, including cancer, viral infections (e.g., HIV) neurodegenerative disorders (e.g. Alzheimer's disease), and cardiovascular disorders (e.g. atherosclerosis). Moreover, certain members of this class are particularly useful for inhibiting cyclin-dependent kinase 7 and are especially useful for the treatment of breast cancer. |
| US08067423B2 |
Polymorphs of dasatinib isopropyl alcohol and process for preparation thereof
The invention provides crystalline forms of isopropyl alcohol solvate of dasatinib, methods for their preparation, and pharmaceutical compositions thereof. |
| US08067419B2 |
Piperazines as antimalarial agents
The invention relates to novel piperazine derivatives and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing one or more of those compounds and their use as medicaments for the treatment or prevention of protozoal infections, especially malaria. |
| US08067418B2 |
Tricyclic angiotensin II agonists
There is provided compounds of formula I, wherein the dotted line, X1, X2, X3, A, Y1, Y2, Y3, Y4, Z1, Z2, R2 and R3 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful as selective agonists of the AT2 receptor, and thus, in particular, in the treatment of inter alia gastrointestinal conditions, such as dyspepsia, IBS and MOF, and cardiovascular disorders. |
| US08067416B2 |
Methods and compositions for the treatment of metabolic disorders
The present invention is directed to a novel methods and compositions for the therapeutic intervention in hyperphenylalaninemia. More specifically, the specification describes methods and compositions for treating various types of phenylketonurias using compositions comprising BH4. Combination therapies of BH4 and other therapeutic regimens are contemplated. |
| US08067412B2 |
Macrocyclic compounds useful as inhibitors of kinases and HSP90
Disclosed are macrocyclic compounds of formulae I-V, which are analogs of the pochonin resorcylic acid lactones, and processes for the preparation of the compounds. The compounds disclosed are useful as inhibitors of kinases and Heat Shock Protein 90 (HSP 90). Also disclosed are pharmaceutical compositions comprising an effective kinase-inhibiting amount or an effective HSP90-inhibiting amount of the compounds and methods for the treatment of disorders that are mediated by kinases and HSP90. |
| US08067406B2 |
Preventive/remedy for retinal nerve diseases containing alkyl ether derivatives or salts thereof
An alkyl ether derivative represented by the following general formula [1] or its salt: wherein R1 and R2 represent each a substituent such as hydrogen, halogeno or alkyl; R3 represents alkylamino, amino or hydroxyl; the ring A represents a 5- or 6-membered aromatic heterocycle or a benzene ring; m and n are each an integer of from 1 to 6; and p is an integer of from 1 to 3; shows an effect of protecting retinal nerve cells and, therefore, is useful as a preventive and/or a remedy for retinal nerve diseases such as glaucoma, diabetic retinopathy, retinal artery obstruction, retinal venous obstruction, macular degeneration and retinopathy of prematurity. |
| US08067395B2 |
Inhibitors of tyrosine kinases and uses thereof
Disclosed herein are compounds that inhibit the activity of particular tyrosine kinases. Methods for the preparation of such compounds are disclosed. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the compounds disclosed, alone or in combination with other therapeutic agents, for the treatment of tyrosine kinase-mediated diseases or conditions or tyrosine kinase-dependent diseases or conditions are provided. |
| US08067392B2 |
Compositions and methods for treatment of mitochondrial diseases
Compounds, compositions, and methods are provided for treatment of disorders related to mitochondrial dysfunction. The methods comprise administering to a mammal a composition containing pyrimidien nucleotide precursors in amounts sufficient to treat symptoms resulting from mitochondrial respiratory chain deficiencies. |
| US08067383B2 |
Synthetic genes and genetic constructs comprising same I
The present invention relates generally to synthetic genes for modifying endogenous gene expression in a cell, tissue or organ of a transgenic organism, in particular a transgenic animal or plant. More particularly, the present invention provides novel synthetic genes and genetic constructs which are capable of repressing delaying or otherwise reducing the expression of an endogenous gene or a target gene in an organism when introduced thereto. |
| US08067382B2 |
Anthelmintic composition
The invention relates to a novel formulation having the advantage of including triclabendazole in solution. In addition a further anthelmintic may be included. The formulation is made by mixing the abamectin and benzyl alcohol and mixing this with triclabendazole and butyl dioxitol. The mix is then heated to dissolve the active, and allowed to cool at which stage the solution is diluted to volume with PEG 4000. The present invention overcomes the solubility difficulties of triclabendazole and presents the triclabendazole in a solution. |
| US08067381B1 |
Methods and compositions for increasing the anaerobic working capacity in tissues
Provided are compositions comprising beta-alanylhistidine peptides and/or beta-alanines, and methods for administering these peptides and amino acids. In one aspect, the compositions and methods cause an increase in the blood plasma concentrations of beta-alanine and/or creatine. |
| US08067376B2 |
Pharmaceutical compositions for transdermal delivery
The present invention relates to a pharmaceutical composition for transdermal administration comprising a conjugate of methotrexate and PTD (protein transduction domain). In accordance with the present invention, the methotrexate, which is widely used for the treatment of psoriasis, rheumatoid and inflammation, etc., can be delivered transdermally to a local part of a patient body, in order to minimize the side effect of the methotrexate. |
| US08067372B2 |
Modulation of angiogenesis by A-beta peptide fragments
Provided are Aβ peptide fragments that are useful in inhibiting angiogenesis. Also provided are methods for the treatment of pathological or unwanted angiogenesis and conditions and diseases associated therewith by administering an effective amount of an Aβ fragment. In a particular embodiment, the peptide fragment includes the sequence HHQKLVFF. |
| US08067371B2 |
RAGE G82S-related methods and compositions for treating inflammatory disorders
This invention provides methods, compositions and articles of manufacture for inhibiting the onset of and treating inflammatory disorders such as rheumatoid arthritis. The instant invention is based on the blockade of RAGE G82S function. |
| US08067368B2 |
Vascular endothelial growth factors and methods of their use
Vascular endothelial growth factor alternative splice variants and methods of their use are provided. |
| US08067366B2 |
Facilitation of resuscitation from cardiac arrest by erythropoietin
The present invention relates generally to the use of erythropoietin (EPO) to facilitate resuscitation from cardiac arrest. For a mammalian subject suffering from cardiac arrest, concurrent administration of EPO with resuscitation after the onset of ventricular fibrillation facilitates the resuscitation. Administration of EPO serves to attenuate myocardial abnormalities caused by cardiac arrest and the resuscitation efforts and favor improved resuscitation outcomes. The main effect of EPO that facilitates resuscitation is the preservation of left ventricular myocardial distensibility leading to improve left ventricular preload and the amount of blood ejected by chest compression. This effect enables higher coronary perfusion pressures to be generated resulting in a higher rate of return of spontaneous circulation and higher survival rates. The very same effect enables the return of spontaneous circulation to occur faster reducing the time a human subject is in cardiac arrest. These effects lead to a higher number of cardiac arrest victims to survive and to do so with intact neurological function in most of the survivors. |
| US08067363B2 |
Compositions and methods for promoting lipid mobilization in humans
Methods of using polypeptide compounds based on the structures of insect peptides of the adipokinetic hormone family to mobilize lipids in humans are provided. The described compositions and methods are useful for modulating human body weight, such as inducing weight loss. Screening methods for identifying other compounds effective for modulating lipid mobilization in humans are also provided. |
| US08067361B2 |
Chaperonin 10 immunosuppression
The invention is directed to the use of cpn10 in transplantation and particularly to treatment and/or prevention of graft versus host disease. The invention provides a method of administration of cpn10 to a donor and/or recipient animal or cells, tissues or organs derived from the donor, although in a particularly advantageous form treatment of both the donor and recipient animal. The method may further include the administration to the donor and/or recipient animal at least one other immunosuppressive agent to prevent or alleviate graft versus host disease. |
| US08067359B2 |
Composition for nutritionally improving glucose control and insulin action
Disclosed is a method and composition for nutritionally improving glucose and insulin balance in an individual. The invention further provides a method for treating a comorbidity of diabetes. In one embodiment, the invention provides a nutritional formulation comprising: a protein source; a fat source; and a carbohydrate source, wherein the protein source, the fat source, and the carbohydrate source are in a ratio of about 1:1:1, each comprising about one third of the total calories of the composition. |
| US08067342B2 |
Internal breakers for viscoelastic surfactant fluids
Internal breakers are given that break fluids viscosified with non-polymeric viscosifiers such as viscoelastic surfactants, inside formation pores. The breakers are polyols, for example natural and synthetic sugars, monoalcohols, and mixtures of the two. The sugars may be ketones and aldehydes. The sugars are also breaker aides for oxidizing agents used as breakers. Methods of using the breakers and breaker aides in oilfield treatment fluids are given. |
| US08067327B2 |
Membranes for highly selective separations
The present invention provides modified molecular sieve membranes with improved CO2/CH4 separation selectivity and methods for making such membranes. The molecular sieve membranes are modified by adsorption of a modifying agent, such as ammonia, within and/or on the membrane. |
| US08067326B2 |
Refractory materials
Refractory materials are provided which contain P2O5/R2O3 constituents, where R is Y, Sc, Er, Lu, Yb, Tm, Ho, Dy, Tb, Gd, or a combination thereof, and/or V2O5/R′2O3 constituents where R′ is Y, Sc, one or more rare earth elements, or a combination thereof. In certain embodiments, the refractory materials are xenotime-type materials and/or xenotime-stabilized zircon-type materials. The refractory materials can be used in the manufacture of glass and glass-ceramics. For example, the refractory materials, especially those that contain P2O5/R2O3 constituents, can be used as forming structures (“isopipes”) in the fusion process for making flat sheets of glass such as the glass sheets used as substrates in the manufacture of flat panel displays. |
| US08067323B2 |
Sintered compact
A sintered cubic boron nitride (cBN) compact for use in a tool is obtained by sintering a mixture of (i) cubic boron nitride, (ii) aluminum oxide, (iii) one or more refractory metal compounds, and (iv) aluminum and/or one or more non-oxide aluminum compounds. The sintered bodies may have sufficient strength and toughness to be used as a tool material in solid, i.e. not carbide supported, form, and may be useful in heavy machining of cast irons. |
| US08067322B2 |
Glass composition for lamp, glass part for lamp, and process for producing lamp or glass composition for lamp
A glass composition for lamps includes the following by weight percent: SiO2: 60-75 wt %; CeO2+Ce2O3: 0.01-5.2 wt %; SnO+SnO2: 0.01-5.2 wt %; Al2O3: 0.5-6 wt %; B2O3: 0-5 wt %; Li2O+Na2O+K2O: 13-20 wt %; MgO: 0.5-5 wt %; CaO: 1-10 wt %; SrO: 0-10 wt %; BaO: 0-10 wt %; ZnO: 0-10 wt %; Fe2O3+FeO: 0-0.2 wt %; and TiO2: 0-1 wt %. The glass composition for lamps that contains no lead or antimony achieves high ultraviolet screening capacity, ensuring fewer occurrences of initial coloring and ultraviolet ray caused coloring of glass. |
| US08067321B2 |
Sodium-potassium hexametaphosphate and potassium metaphosphate with a low insolubles content
Potassium-containing polyphosphate glasses having a relatively high amount of potassium and a relatively low level of insoluble material (e.g., less than about 10% by weight), and a method for their production that includes using a boron-containing glass-former additive. More specifically, these polyphosphate glasses may be described according to the formula M(n+2)O(PO3)n, where M is at least K or K+Na and the glasses have a mole % M-as-K that is about 33 to 100. These polyphosphate glasses may be used in reduced sodium foods (e.g., beverages and meat products). |
| US08067316B2 |
Method for manufacturing memory element
A conductive paste including conductive particles each of which has a size of greater than or equal to 0.1 μm and less than or equal to 10 μm, a resin, and a solvent is placed over a first conductor and the solvent is vaporized. In this manner, a second conductor having the conductive particles and a memory layer including the resin between the first conductor and the conductive particles is formed. |
| US08067314B2 |
Gate trim process using either wet etch or dry etch approach to target CD for selected transistors
Disclosed are methods and devices for targeting CD of selected transistors in a semiconductor device. Varying CD is done by forming hard mask lines in a hard mask layer that have varying amounts of spacer material associated therewith. Hard mask lines corresponding to selected transistors are either left covered or uncovered by a resist applied over the hard mask layer. Then, spacer material is selectively removed from the hard mask lines to vary the width of hard mask lines and associated side wall spacers. A gate layer is then etched through the spaces in the hard mask lines to form gate lines having varying widths and targeted CD. |
| US08067312B2 |
Coaxial through chip connection
An integrated circuit chip includes devices formed by doping of a semiconductor on a substrate and at least one post-device formation through-chip via made up of an annulus of insulating material, an annulus of metallization bounding an outer surface of the annulus of insulating material and an annulus of electrically conductive material within the annulus of insulating material, the annulus of metallization and the annulus of electrically conductive material being electrically isolated from each another. |
| US08067310B2 |
Semiconductor device and method for manufacturing of same
A method for manufacturing a semiconductor device, includes: forming a first metal layer on a semiconductor substrate, the semiconductor substrate including a diffusion layer; forming an insulating layer having an opening on the first metal layer; forming a second metal layer on the first metal layer in the opening of the insulating layer; removing the insulating layer; covering an exposed surface of the second metal layer with a third metal layer, the third metal layer including a metal having an ionization tendency lower than that of the second metal layer; and forming an electrode interconnect including the first metal layer, the second metal layer, and the third metal layer by removing the first metal layer using the third metal layer as a mask. |
| US08067309B2 |
Semiconductor device using metal nitride as insulating film and its manufacture method
A first insulating film is formed on a semiconductor substrate. A second insulating film made of insulating metal nitride is formed on the first insulating film. A recess is formed through the second insulating film and reaches a position deeper than an upper surface of the first insulating film. A conductive member is buried in the recess. A semiconductor device is provided whose interlayer insulating film can be worked easily even if it is made to have a low dielectric constant. |
| US08067305B2 |
Electrically conductive structure on a semiconductor substrate formed from printing
Provided are methods for forming an electrically conductive structure of a desired three-dimensional shape on a substantially planar surface of a substrate, e.g., a semiconductor wafer. Typically, the particulate matter is deposited in a layer-by-layer manner and adhered to selected regions on the substrate surface. The particulate matter may be deposited to produce a mold for forming the structure and/or to produce the structure itself. A three-dimensional printer with associated electronic data may be used without the need of a lithographic mask or reticle. |
| US08067303B1 |
Solid state energy conversion device
A solid state energy conversion device and method of making is disclosed for converting energy between electromagnetic and electrical energy. The solid state energy conversion device comprises a wide bandgap semiconductor material having a first doped region. A thermal energy beam is directed onto the first doped region of the wide bandgap semiconductor material in the presence of a doping gas for converting a portion of the first doped region into a second doped region in the wide bandgap semiconductor material. A first and a second Ohmic contact are applied to the first and the second doped regions of the wide bandgap semiconductor material. In one embodiment, the solid state energy conversion device operates as a light emitting device to produce electromagnetic radiation upon the application of electrical power to the first and second Ohmic contacts. In another embodiment, the solid state energy conversion device operates as a photovoltaic device to produce electrical power between the first and second Ohmic contacts upon the application of electromagnetic radiation. |
| US08067301B2 |
Image sensor and method for forming the same
A reliable image sensor and a method for forming the same are provided. The image sensor includes a photo-detective device. At least one transistor is electrically connected to the photo-detective device for outputting charges stored in the photo-detective device. A transistor directly connected to the photo-detective device includes a gate electrode pattern and an ion-implantation interrupting pattern arranged on the gate electrode pattern. Since the ion-implantation interrupting pattern is located on an upper portion of the gate electrode pattern of the transistor in the vicinity of the photo-detective device, a threshold voltage of the gate electrode pattern of the transistor in the vicinity of the photo-detective device is adjusted to a desired value. |
| US08067300B2 |
AlxInyGa1-x-yN mixture crystal substrate, method of growing same and method of producing same
Seeds are implanted in a regular pattern upon an undersubstrate. An AlxInyGa1-x-yN (0≦x≦1, 0≦y≦1, 0 |
| US08067291B2 |
MOS field-effect transistor and manufacturing method thereof
To provide a manufacturing method of a MOS field-effect transistor in which such a structure is adopted that SiGe having a large lattice constant is embedded immediately below a channel and distortion is effectively introduced in a channel Si layer so that mobility of electrons or holes are drastically improved, thereby realizing high-speed operation and low power consumption. A stressor 2 composed of silicon germanium is formed in a portion in an active region that is separated by an insulating film formed on a silicon substrate, a silicon channel layer 1 composed of silicon is formed above the stressor, and a tensile stress layer 10 is formed so as to surround a gate electrode and a sidewall formed on the gate electrode. |
| US08067290B2 |
Bipolar transistor with base-collector-isolation without dielectric
The disclosed invention provides a method for the fabrication of a bipolar transistor having a collector region comprised within a semiconductor body separated from an overlying base region by one or more isolation cavities (e.g., air gaps) filled with low permittivity gas. In particular, a multilayer base-collector dielectric film is deposited over the collector region. A base region is formed onto the multilayer dielectric film and is patterned to form one or more base connection regions. The multilayer dielectric film is selectively etched during a plurality of isotropic etch processes to allow for the formation of one or more isolation region between the base connection regions and the collector region, wherein the one or more isolation regions comprise cavities filled with a gas having a low dielectric constant (e.g., air). The resultant bipolar transistor has a reduced base-collector capacitance, thereby allowing for improved frequency properties (e.g., higher maximum frequency operation). |
| US08067289B2 |
Semiconductor device and manufacturing method thereof
A semiconductor device and a method of manufacturing a semiconductor device. A semiconductor device may include an epitaxial layer over a semiconductor substrate, a first well region over a epitaxial layer, a first isolation layer and/or a third isolation layer at opposite sides of said first well region and/or a second isolation layer over a first well region between first and third isolation layers. A semiconductor device may include a gate over a second isolation layer. A semiconductor device may include a second well region over a first well region between a third isolation layer and a gate, a first ion-implanted region over a second well region between a third isolation layer and a gate, and/or a second ion-implanted region between a first ion-implanted region and a gate. A semiconductor device may include an accumulation channel between a second well region and a gate. |
| US08067288B2 |
Configuration and method of manufacturing the one-time programmable (OTP) memory cells
This invention discloses a method for manufacturing a one-time programmable (OTP) memory includes a first and second MOS transistors connected in parallel and controlled by a common gate formed with a single polysilicon stripe. The method further comprises a step of implanting a drift region in a substrate region below a drain and source of the first and second MOS transistors counter doping a lightly dope drain (LDD) encompassing and surrounding a drain and a source of the first MOS transistor having a different threshold voltage than the second MOS transistor not reached by the drift region. |
| US08067286B2 |
Methods of forming recessed access devices associated with semiconductor constructions
The invention includes methods of forming recessed access devices. A substrate is provided to have recessed access device trenches therein. A pair of the recessed access device trenches are adjacent one another. Electrically conductive material is formed within the recessed access device trenches, and source/drain regions are formed proximate the electrically conductive material. The electrically conductive material and source/drain regions together are incorporated into a pair of adjacent recessed access devices. After the recessed access device trenches are formed within the substrate, an isolation region trench is formed between the adjacent recessed access devices and filled with electrically insulative material to form a trenched isolation region. |
| US08067281B1 |
Method of fabricating complementary metal-oxide-semiconductor (CMOS) Device
A method of fabricating a CMOS device is provided. First, first and second gates, first and second offset spacers and first and second lightly-doped regions are respectively formed in first and second type metal-oxide-semiconductor regions. A mask layer is respectively formed on the first and second gates. Next, an epitaxial layer is formed in the substrate on two sides of the second gate. Next, first and second spacers, first and second doped regions are formed. Next, a portion of the first spacer is removed to expose a portion of a surface of the first lightly-doped region, thereby forming a first slimmed spacer. Next, a coating layer containing silicon is formed to cover the exposed first lightly-doped region, the first and second doped regions. Next, the mask layer is removed. Next, a metal silicide layer is formed on the first and second gates and the silicon layer. |
| US08067280B2 |
High performance CMOS devices and methods for making same
An integrated circuit having high performance CMOS devices with good short channel effects may be made by forming a gate structure over a substrate; forming pocket implant regions and source/drain extensions in the substrate; forming spacers along sides of the gate structure; and thermal annealing the substrate when forming the spacers, the thermal annealing performed at an ultra-low temperature. An integrated circuit having high performance CMOS devices with low parasitic junction capacitance may be made by forming a gate structure over a substrate; forming pocket implant regions and source/drain extensions in the substrate; forming spacers along sides of the gate structure; performing a low dosage source/drain implant; and performing a high dosage source/drain implant. |
| US08067276B2 |
Semiconductor device and manufacturing method thereof
An oxide or nitride semiconductor layer is formed over a substrate. A first conductive layer including a first element and a second element, and a second conductive layer including the second element are formed over the semiconductor layer. The first element is oxidized or nitrogenized near an interface region between the first conductive layer and the oxide or nitride semiconductor layer by heat treatment or laser irradiation. The Gibbs free energy of oxide formation of the first element is lower than those of the second element or any element in the oxide or nitride semiconductor layer. |
| US08067271B2 |
Integrated circuit package system with encapsulation lock
An integrated circuit package system is provided including forming an external interconnect and a tie bar, forming a lead tip and a lead body of the external interconnect, forming a hole in the external interconnect, forming a slot in the tie bar, connecting an integrated circuit die and the external interconnect, and molding the external interconnect and the tie bar with the slot and the hole filled. |
| US08067270B2 |
Method of making a semiconductor chip assembly with a post/base heat spreader and a substrate
A method of making a semiconductor chip assembly includes providing a post and a base, mounting an adhesive on the base including inserting the post through an opening in the adhesive, mounting a substrate on the adhesive including inserting the post into an aperture in the substrate to form a gap in the aperture between the post and the substrate, then flowing the adhesive into and upward in the gap, solidifying the adhesive, then mounting a semiconductor device on a heat spreader that includes the post and the base, electrically connecting the semiconductor device to the substrate and thermally connecting the semiconductor device to the heat spreader. |
| US08067267B2 |
Microelectronic assemblies having very fine pitch stacking
A method of making a stacked microelectronic assembly includes providing a first microelectronic package that includes a first substrate having a first dielectric layer, conductive posts, and conductive traces extending along the surface of the first dielectric layer; providing a second microelectronic package including a second substrate that includes a second dielectric layer; securing a microelectronic element to one of the surfaces of at least one of the first or second substrates; and joining the conductive posts of the first substrate with the fusible masses of the second substrate. The posts may include a plurality of aligned posts which are aligned in a first row extending in a single orthogonal direction along a surface of the first substrate away from a portion of the first substrate that faces a face of the microelectronic element. The aligned posts are disposed beyond one of the edges of the microelectronic element. |
| US08067266B2 |
Methods for the fabrication of microelectronic device substrates by attaching two cores together during fabrication
The present disclosure relates to fabricating substrates for use in microelectronic device packages. In at least one embodiment, two substrate cores may be attached together during build-up layer formation on each substrate core to increase substrate fabrication throughput. The embodiments of the present disclosure may allow the processing of relatively thin substrates. |
| US08067265B2 |
Electric devices and methods of manufaturing the same
A process for manufacturing an electrical device, the process comprising the steps: providing a substrate; bringing a stamp into contact with the substrate whereby areas of the substrate contacted by the stamp have decreased wettability; and depositing a liquid comprising an electrically active material over areas of the substrate located between the areas of decreased wettability. |
| US08067263B2 |
Thermal management and method for large scale processing of CIS and/or CIGS based thin films overlying glass substrates
The thermal management and method for large scale processing of CIS and/or CIGS based thin film overlaying glass substrates. According to an embodiment, the present invention provides a method for fabricating a copper indium diselenide semiconductor film. The method includes providing a plurality of substrates, each of the substrates having a copper and indium composite structure. The method also includes transferring the plurality of substrates into a furnace, each of the plurality of substrates provided in a vertical orientation with respect to a direction of gravity, the plurality of substrates being defined by a number N, where N is greater than 5. The method further includes introducing a gaseous species including a selenide species and a carrier gas into the furnace and transferring thermal energy into the furnace to increase a temperature from a first temperature to a second temperature, the second temperature ranging from about 350° C. to about 450° C. to at least initiate formation of a copper indium diselenide film from the copper and indium composite structure on each of the substrates. |
| US08067262B2 |
Polymeric precursors for CAIGS silver-containing photovoltaics
This invention relates to compounds, polymeric compounds, and compositions used to prepare semiconductor and optoelectronic materials and devices including thin film and band gap materials. This invention provides a range of compounds, polymeric compounds, compositions, materials and methods directed ultimately toward photovoltaic applications, transparent conductive materials, as well as devices and systems for energy conversion, including solar cells. In particular, this invention relates to polymeric precursor compounds and precursor materials for preparing photovoltaic layers. A compound may contain repeating units {MB(ER)(ER)} and {MA(ER)(ER)}, wherein MA is a combination of Cu and Ag, each MB is In or Ga, each E is S, Se, or Te, and each R is independently selected, for each occurrence, from alkyl, aryl, heteroaryl, alkenyl, amido, silyl, and inorganic and organic ligands. |
| US08067257B2 |
Nitride based semiconductor optical device, epitaxial wafer for nitride based semiconductor optical device, and method of fabricating semiconductor light-emitting device
In the nitride based semiconductor optical device LE1, the strained well layers 21 extend along a reference plane SR1 tilting at a tilt angle α from the plane that is orthogonal to a reference axis extending in the direction of the c-axis. The tilt angle α is in the range of greater than 59 degrees to less than 80 degrees or greater than 150 degrees to less than 180 degrees. A gallium nitride based semiconductor layer P is adjacent to a light-emitting layer SP− with a negative piezoelectric field and has a band gap larger than that of a barrier layer. The direction of the piezoelectric field in the well layer W3 is directed in a direction from the n-type layer to the p-type layer, and the piezoelectric field in the gallium nitride based semiconductor layer P is directed in a direction from the p-type layer to the n-type layer. Consequently, the valence band, not the conduction band, has a dip at the interface between the light-emitting layer SP− and the gallium nitride based semiconductor layer P. |
| US08067256B2 |
Method of making microelectronic package using integrated heat spreader stiffener panel and microelectronic package formed according to the method
A method of making a microelectronic package, and a microelectronic package made according to the method. The method includes: bonding and thermally coupling a plurality of IC dies to an IHS panel to yield a die-carrying IHS panel; mounting the die-carrying IHS panel onto a substrate panel including a plurality of package substrates to yield a combination including the die-carrying IHS panel mounted to the substrate panel; and singulating the combination to yield a plurality of microelectronic packages, each of the packages including: an IHS component of the IHS panel, one of the plurality IC dies bonded and thermally coupled to said IHS component and one of the plurality of package substrates, said IHS component and said one of the plurality of IC dies being mounted to said one of the plurality of package substrates to form said each of the packages. |
| US08067248B2 |
Method for diagnosing rheumatoid arthritis via assaying myofibroblast-like synoviocytes for fibroblast activation protein
The invention relates to methods for diagnosing rheumatoid arthritis by assaying for Fibroblast Activation Protein Alpha expression in rheumatoid, myofibroblast like synoviocytes. Therapeutic aspects are also a part of the invention. |
| US08067247B2 |
Use of anti-CD100 antibodies for the treatment of inflammatory disorders affecting the central or peripheral nervous system
The invention relates to the use a BD16 and/or BB18 anti-CD100 antibody or of a chimeric or humanized or human form thereof, or a fragment thereof, for the therapy or diagnosis of a central nervous system disorder, more particularly a myelin disorder or a disease that affects oligodendrocytes, such as multiple sclerosis or HTLV-1 associated myelopathy or peripheral myelinating cells. |
| US08067245B2 |
Automated microscope for blood cell analysis
An apparatus and method of automated blood cell analysis uses technologies from other systems to create a new, robust, improved type of automated microscope, which uses electronic motors and a closed loop control system to minimize ambient factors, such as jarring and temperature changes. Pre-stained blood smear slides are first coated with a thin film of oil and are loaded into a carousel from which they can individually be analyzed. The slides are moved under a low magnification microscope; an optimal area of examination is determined; a focal plane map is calculated for that area, and the positions of white blood cell candidates are computed. The slide is then moved under a high power microscope where a refined focal plane map is computed and the individual white blood cell candidates are imaged. The cells are preclassified and the images are made available for analysis by the technician. Additionally, samples of red blood cells, equivalent to what the technician would do manually, are imaged and presented to the technician for evaluation. The technician may make notes on those cells, both red and white blood cells and archive them. |
| US08067244B2 |
Method and device for investigation of a surface layer
A method and device for investigation of a surface layer of a material. The material without surface layer is exposed for a gas and the penetration of the gas into the material is measured. Then the surface layer is applied to the material. Finally, the material including the surface layer is exposed for the gas and the penetration of the gas into the material through the surface layer is measured. The measurement of the passage of the gas into the material is performed by a method comprising measurement of light absorption by the gas by absorption spectroscopy. |
| US08067243B2 |
Methods and systems for analyzing medication levels in a sample
Methods and systems for assessing patient compliance with opioid drug therapy are provided. A liquid chromatography tandem mass spectrometer (LC/MS/MS) can be used to simultaneously detect a set of measurements including an amount of at least ten opioids (and their metabolites) in a body fluids sample from a patient. The set of at least ten opioids can include at least oxymorphone and fentanyl. The amounts of opioids and their metabolites are analyzed. For example, the ratios of opioids and their respective metabolites can be used to determine which opioids a patient has been administered. A report of patient compliance is generated based on the set of measurements. |
| US08067240B2 |
Methods for the diagnosis and treatment of lung cancer
The present invention provides methods for aiding in the diagnoses of the neoplastic condition of a lung cell and methods of screening for a potential therapeutic agent for the reversal of the neoplastic condition. |
| US08067236B2 |
Optimized human T1R3 nucleic acid molecule
The present invention relates to a screening system for modulators of GPCRs. Further it relates to recombinant vector systems for the heterologous expression of heterodimeric g-protein coupled receptors (GPCRs) in eukaryotic host cells. Preferably the functional expression of engineered GPCRs for the perception of sweet and L-amino acid taste or more preferably the use of these receptors for the identification of functional ligands is also encompassed. |
| US08067231B2 |
Clostridial toxin activity assays
Compositions useful for detecting Clostridial toxin activity comprising a cell that contains an exogenous Clostridial toxin substrate which comprises a fluorescent member, a membrane targeting domain and a Clostridial toxin recognition sequence comprising a cleavage site, where the cleavage site intervenes between the fluorescent member and the membrane targeting domain; and methods useful for determining Clostridial toxin activity using such Clostridial toxin substrates. |
| US08067224B2 |
Presenilin associated membrane protein (PAMP) and uses thereof
Presenilin Associated Membrane Protein (PAMP), and nucleic acids encoding this protein, are provided. PAMP and PAMP nucleic acids provide diagnostic and therapeutic tools for evaluating and treating or preventing neurodegenerative diseases. In a specific embodiment, mutations in PAMP are diagnostic for Alzheimer's Disease or spina bifida. The invention further relates to screening, particularly using high-throughput screens and transgenic animal models, for compounds that modulate the activity of PAMP and presenilins. Such compounds, or gene therapy with PAMP, can be used in treating neurodegenerative diseases, particularly Alzheimer's Disease. In addition, the invention provides PAMP mutants, nucleic acids encoding for PAMP mutants, and transgenic animals expressing PAMP mutants, which in a preferred aspect result in biochemical changes similar to those induced by mutations in βAPP, PS1, or PS2, associated with familial Alzheimer's disease. |
| US08067221B2 |
Von Willebrand factor (vWF)-cleaving protease
This invention is intended to isolate and identify a vWF-specific cleaving protease. The vWF-specific cleaving protease cleaves a bond between residues Tyr 842 and Met 843 of vWF and comprises a polypeptide chain having Leu-Leu-Val-Ala-Val (SEQ ID NO: 1) as a partial sequence, and more preferably comprises a polypeptide chain having the partial N-terminal amino acid sequence of a mature protein, Ala-Ala-Gly-Gly-Ile-Leu-His-Leu-Glu-Leu-Leu-Val-Ala-Val (SEQ ID NO: 2), and having a molecular weight of 105 to 160 kDa in SDS-PAGE under reducing or non-reducing conditions. Isolation and identification of this vWF-specific cleaving protease have led to the possibility of replacement therapy for patients having diseases resulting from a deficiency of the protease, such as thrombotic thrombocytopenic purpura. |
| US08067220B2 |
Alternative crystal form of monoacylglycerol lipase (MGLL)
A number of soluble engineered forms of MGLL that are suitable for high-throughput screening and protein crystallization, as well as a crystallized forms of monoacylglycerol lipase protein (MGLL) and descriptions of the X-ray diffraction patterns are disclosed. The engineered constructs of MGLL permit the expression and purification of protein suitable for crystallography or high-throughput screening and identification of ligands, which can function as active agents to MGLL. The X-ray diffraction patterns allow the three dimensional structure of MGLL to be determined at atomic resolution so that ligand binding sites on MGLL can be identified and the interactions of ligands with MGLL amino acid residues can be modeled. Models prepared using such maps permit the design of ligands which can function as active agents which include, but are not limited to, those that function as inhibitors of MGLL. |
| US08067216B2 |
Method for macerating biological material and apparatus for carrying out said method
In order to ensure consistently good maceration of biological material in an electroporation reactor, it is proposed to monitor the conductivity of the mixture therein and to detect any arcing which occurs therein. The results of such monitoring are used to modify the operating voltage of the electroporation reactor and/or the composition of the mixture located in the reactor channel. |
| US08067215B2 |
Process of producing polymers
A process for preparing a polymer of an ethylenically unsaturated monomer, in which the monomer is obtainable from a biocatalysed reaction or a fermentation process, and wherein the monomer contains cellular material and/or components of a fermentation broth, forming the polymer by polymerizing the ethylenically unsaturated monomer or a monomer mixture comprising the ethylenically unsaturated monomer, wherein there is substantially no removal of the cellular material and/or components of the fermentation broth from the ethylenically unsaturated monomer. |
| US08067210B2 |
Method of producing lysine by culturing a host cell expressing a polynucleotide encoding a feedback resistant aspartokinase from corynebacterium
The invention provides methods to increase the production of an amino acid from Corynebacterium species by way of the amplification of amino acid biosynthetic pathway genes in a host cell chromosome. The invention also provides novel processes for the production of an amino acid by way of the amplification of amino acid biosynthetic pathway genes in a host cell chromosome and/or by increasing promoter strength. In a preferred embodiment, the invention provides processes to increase the production of L-lysine in Corynebacterium glutamicum by way of the amplification of L-lysine biosynthetic pathway genes in a host cell chromosome. The invention also provides novel isolated nucleic acid molecules for L-lysine biosynthetic pathway genes of Corynebacterium glutamicum. |
| US08067206B2 |
Enhanced coamplification of nucleic acids
The present invention relates generally to the field of nucleic acid chemistry. More specifically, it relates to a method for enhancing the performance of coamplification reactions, e.g., multiplex PCR reactions. |
| US08067204B2 |
Long-chain chondroitin sugar chain and method for producing the same and method for promoting synthesis of chondroitin
A method for producing a chondroitin sugar chain comprises reacting a glucuronic acid donor, an N-acetyl galactosamine donor, a sugar receptor and a bacterial cell enzyme which synthesizes chondroitin in the presence of a surfactant. The surfactant is selected from polyoxyethylene octadecyl amine, n-decanoyl-N-methylglucamide, sodium cholate, n-octyl-β-D-thioglucopyranoside, n-nonyl-β-D-thiomaltopyranoside, sucrose monocholate, sucrose monocaprate, and sucrose monolaurate. The chondroitin sugar chain has all the following properties: a weight average molecular weight: 50,000 or more when measured by gel filtration chromatography; it is completely degraded to disaccharides with chondroitinase ABC; and when the sugar chain is decomposed with chondroitinase ABC and the decomposed products are subjected to a disaccharide analysis, substantially all of them correspond to an unsaturated disaccharide unit of chondroitin. |
| US08067203B2 |
Composition for treating porcine progressive atrophic rhinitis and making process thereof
The present invention relates to an animal vaccine directed to progressive atrophic rhinitis (PAR), comprising at least two fragments of recombinant subunit Pasteurella multocida toxins (rsPMT) capable of eliciting the production of antibodies against Pasteurella multocida associated with PAR, and to a method for producing the animal vaccine of the invention, said fragments each having an amino acid sequence that substantially corresponds to the 2-486, 486-986 or 986-1281 amino acid residues of Pasteurella multocida toxin (PMT), respectively. Also disclosed is a multivalent animal vaccine, comprising said fragments as active components against PAR, and at least a pathogenic antigen or epitope thereof associated with other animal disease(s), such as inactivated gE-deleted Pseudorabies virus. |
| US08067201B2 |
Methods for protein refolding
Provided herein are methods for refolding proteins. The methods involve covalently modifying a denatured protein with a nonproteinaceous polymer and then renaturing the modified protein. |
| US08067200B2 |
Fusion proteins
A single chain, polypeptide fusion protein, comprising: a non-cytotoxic protease, or a fragment thereof, which protease or protease fragment is capable of cleaving a protein of the exocytic fusion apparatus of a nociceptive sensory afferent; a Targeting Moiety that is capable of binding to a Binding Site on the nociceptive sensory afferent, which Binding Site is capable of undergoing endocytosis to be incorporated into an endosome within the nociceptive sensory afferent; a protease cleavage site at which site the fusion protein is cleavable by a protease, wherein the protease cleavage site is located between the non-cytotoxic protease or fragment thereof and the Targeting Moiety; and a translocation domain that is capable of translocating the protease or protease fragment from within an endosome, across the endosomal membrane and into the cytosol of the nociceptive sensory afferent. Nucleic acid sequences encoding the polypeptide fusion proteins, methods of preparing same and uses thereof are also described. |
| US08067194B2 |
Hydrolysis process for raw materials from the fishing and slaughterhouse industries and tanks for use therein
The invention relates to a method and hydrolysis tank for enzymatic hydrolysis of raw materials containing collagen and proteins to produce the three layers: a top layer containing fat, a mid-layer comprising water soluble constituents and denatured collagen, and a non-soluble bottom layer comprising bones and non-soluble proteins. These layers are separated and the second layer is further separated by cooling for a time period sufficient to form two layers: a bottom layer containing partially or wholly set collagen, and a liquid top layer containing the remaining water soluble proteins which are removed. The other is heated until it becomes liquid. The hydrolysis tank comprises a turnable stirring mechanism, a device for heat exchange and a reversible screw that is arranged in the bottom of the tank. A clearing sump for separation of collagen, includes an inlet for supply of hydrolysate. |
| US08067192B2 |
Methods for detection of botulinum neurotoxin
Provided herein is a large immuno-sorbent surface area assay (ALISSA) for rapid and sensitive detection of toxin or enzyme activity. This assay is designed to capture a low number of toxin or enzyme molecules and to measure their intrinsic protease activity via conversion of a fluorogenic or luminescent substrate. The ALISSA is significantly faster and more sensitive than methods routinely utilized in the art. This assay is applicable for use for detection of a variety of toxins or enzymes having proteolytic activity, such as botulinum neurotoxin, bacillus anthracis lethal factor, human chitinases, and aspergillus fumigatus proteases. Also provided are methods for constructing and identifying novel luminescent or fluorescent substrates suitable for use with the ALISSA method. |
| US08067188B2 |
Analyte detection
The present invention relates to analyte detection test systems, including test systems for the oral detection of analytes in saliva. The present invention also provides compositions and methods for storing multiple assay tests and compositions and methods for measuring the concentration of analytes in a sample. |
| US08067186B2 |
Monoclonal antibody DS6, tumor-associated antigen CA6, and methods of use thereof
The present application describes a monoclonal antibody selected from the group consisting of monoclonal antibody DS6, monoclonal antibodies that specifically bind to the antigen or epitope bound by monoclonal antibody DS6, and fragments of the foregoing that specifically bind to the antigen or epitope bound by monoclonal antibody DS6. Methods of use of such antibodies and the isolated antigen bound by such antibodies are also described. |
| US08067185B2 |
Methods of quantifying taste of compounds for food or beverages
Methods of quantifying the taste of compounds for food and beverages are provided. These methods comprise contacting the compounds with an isolated heteromeric receptor comprising at least one T1R1 polypeptide and at least one T1R3 polypeptide. |
| US08067181B2 |
MELKS as modifiers of the Rac pathway and methods of use
Human MELK genes are identified as modulators of the RAC pathway, and thus are therapeutic targets for disorders associated with defective RAC function. Methods for identifying modulators of RAC, comprising screening for agents that modulate the activity of MELK are provided. |
| US08067180B2 |
MAPKs as modifiers of the rac, axin, and beta-catenin pathways and methods of use
Human MAPK genes are identified as modulators of the Rac, axin, and beta-catenin pathways, and thus are therapeutic targets for disorders associated with defective Rac, axin, and beta-catenin function. Methods for identifying modulators of Rac, axin, and beta-catenin, comprising screening for agents that modulate the activity of MAPK are provided. |
| US08067179B2 |
Immunoglobulin libraries
Methods and compositions for the screening and isolation of ligand-binding polypeptides, such as antibodies. In some aspects, methods of the invention enable the isolation of intact soluble antibodies comprising a constant domain. Screening methods that employ genetic packages such as bacteria and bacteriophages enable high through-put identification of ligand binding molecules. |
| US08067177B2 |
Amplification methods
Methods are provided for amplification and monitoring of oligonucleotide amplification in which a primer has an overlap with one or more bases of a detection probe. |
| US08067174B1 |
Polymerase chain reaction (PCR) method for amplifying a DNA template
The present invention relates to a DNA polymerase immobilized by covalent bonding. More particularly, the present invention relates to an immobilized DNA polymerase whose activity is maximally preserved by masking the active site of the DNA polymerase and optimizing interaction of the masked molecule to the substrate material. In one embodiment, the average activity of the immobilized DNA polymerase is more than about 10% relative to that of the solution phase DNA polymerase. Further provided by the invention are methods and kits for performing polymerase chain reactions (PCR). |
| US08067170B2 |
Binding method and apparatus for sorting objects
The present invention relates to a method and apparatus of sorting objects including, providing a sample having wanted objects and unwanted objects; coating a surface of a sample holder with an antibody; placing an eluted sample on the sample holder; binding an antigen in the wanted objects with the antibody on the surface of the sample holder to sort the objects into wanted objects and unwanted objects; separating the wanted objects; and performing PCR-based STR analysis on the wanted objects. In one embodiment, holographic optical trapping is used to further sort the wanted objects. In other embodiments, the wanted objects are sperm and the antibody is a human sperm specific antibody, and the PCR is single cell PCR-based STR analysis. In still other embodiments, the binding is direct or indirect, ligands are used to bind to object-specific organomolecules, and protein A or protein G are used to bind the antibody. |
| US08067159B2 |
Methods of detecting amplified product
A microfluidic device comprising a first surface portion and a first sample retaining element, which have differing affinities to a fluid, and a method comprising supplying a sample to such a device. In some embodiments, the differing affinity is a result of plasma, ion embedding, surface charging, chemical, optical, electronic and/or electromagnetic treatment. Also, a microfluidic device comprising at least one microcapillary device having a sample retaining element, at least one surface of which exhibits hydrophobicity, hydrophilicity, electromagnetic force exertion and electrostatic force exertion. Also, a microfluidic device comprising a first element having a hydrophilic pattern comprising at least a first sample retaining element. Also, a method comprising supplying a sample to a channel between a first element and a second element, and inducing in the first element at least one hydrophilic pattern by electrets or by internal or external electrodes to provide a charged surface. |
| US08067153B2 |
Genes and polypeptides relating to prostate cancers
The present application provides novel human gene ELOVL7 whose expression is markedly elevated in prostate cancers. The gene and polypeptide encoded by the gene can be used, for example, in the diagnosis of prostate cancers, as target molecules for developing drugs against the disease, and for attenuating cell growth of prostate cancer. |
| US08067148B2 |
Pattern forming method
A resist film of a positive type containing a photoacid generator is formed on a substrate. Then, pattern exposure is performed by selectively irradiating the resist film with exposure light. Thereafter, first heating is performed on the resist film subjected to the pattern exposure. After the heating, first development is performed on the resist film, thereby forming a first resist pattern. Subsequently, the first resist pattern is exposed to a solution containing a thermal acid generator and containing neither polymer nor a cross-linking agent. After the exposure, second heating is performed on the first resist pattern. Second development is then performed on the first resist pattern, thereby forming a second resist pattern made of the first resist pattern having a reduced size. |
| US08067146B2 |
Method for forming a fine pattern in a semicondutor device
A method for forming a fine pattern a semiconductor device includes the steps of forming a first photoresist pattern over a semiconductor substrate having an underlying layer; coating a pattern hardening coating agent over the first photoresist pattern, thereby forming a pattern hardening film; forming a second photoresist film over the resulting structure; and selectively exposing and developing the second photoresist film, thereby forming a second photoresist pattern to be defined between neighboring first photoresist pattern. |
| US08067142B2 |
Coating, system and method for conditioning prints
Disclosed herein is a xerographic print comprising a substrate having a printed image thereon comprising a low melt temperature toner, and a polyolefin wax coating formed over the printed image having a dry thickness in the range of about 0.5 to about 5 microns. The wax coating substantially prevents toner offset at temperatures up to at least 70° C. A printing system and coating method also are disclosed. The prints, printing system and method are useful for making brochures and books that will be subjected to high temperatures, pressures, and/or humidity levels, such as manuals stored in automobile glove compartments. |
| US08067141B2 |
Electrographic carrier, developer, developing method, image forming apparatus, and process cartridge
A carrier is provided including a core and a resin layer located overlying the core, wherein the carrier has a weight average particle diameter (Dw) of from 22 to 50 μm, a ratio (Dw/Dp) of the weight average particle diameter (Dw) to a number average particle diameter (Dp) of from 1 to 1.30, a shape factor SF-1 of from 100 to 120, and a shape factor SF-2 of from 100 to 120, and wherein the carrier comprises core particles satisfying the following relationship 0.52<(d/D)<1.0 in an amount of from 0 to 10,000 ppm by number: wherein D (μm) represents a diameter of a circle having the same area as that of a projected image of a core particle and d (μm) represents a diameter of a circle having the same area as that of a projected image of a maximum hollow present in the core particle. |
| US08067139B2 |
Resin mixture backing layer containing photoconductor
A photoconductor that includes, for example, a backing layer, a supporting substrate, a photogenerating layer, and a charge transport layer, and where the outermost layer of the backing layer is comprised of a mixture of a glycoluril resin and a polyol resin. |
| US08067137B2 |
Polymer containing charge transport photoconductors
A photoconductor that includes a supporting substrate, a photogenerating layer, and at least one charge transport layer that contains at least one charge transport component, and a polysiloxane/polyetherimide polymer. |
| US08067134B2 |
Method of iterative compensation for non-linear effects in three-dimensional exposure of resist
The field of this disclosure is making three-dimensional topographic structures by means of graduated exposure in a photosensitive material, such as a photoresist, photosensitive polymide, or similar. Such patterns may be written either to be used directly as optical, mechanical, fluidic, etc. components, e.g. diffusors, non-reflecting surfaces, Fresnel lenses and Fresnel prisms, computer-generated holograms, lenslet arrays, etc, or to be used as masters for the fabrication of such components by replication. Replication can be done by molding, pressing, embossing, electroplating, etching, as known in the art. This disclosure includes descriptions of using passive absorbing components in thin resist, using high gamma thick resists with high resolution pattern generators, using multiple focal planes including at least one focal plane in the bottom half of the resist, and iterative simulation of patterning and adjustment of an exposure map. |
| US08067130B2 |
Catalyst-coated membrane with integrated sealing material and membrane-electrode assembly produced therefrom
The invention relates to a catalyst-coated ion-conducting membrane and a membrane-electrode assembly (MEA) for electrochemical devices, in particular for fuel cells. The catalyst-coated, ion-conducting membrane is provided with a sealing material which is applied in the edge region to one side of the membrane and has a thickness which corresponds to at least the total thickness of the catalyst-coated membrane. Owing to their simple, material-conserving construction, the catalyst-coated ion-conducting membranes and the membrane-electrode assemblies produced therefrom can be manufactured inexpensively. They are used in PEM fuel cells, direct methanol fuel cells (DMFCs), electrolyzers and other electrochemical devices. |
| US08067127B2 |
Fuel cell system and control method thereof for detecting a chemical short
A fuel cell system is provided with a fuel cell (20) which generates electricity by a chemical reaction between a fuel gas supplied to an anode side of the fuel cell and an oxidization gas supplied to a cathode side of the fuel cell; estimating means (50) for estimating whether there is a possibility that a chemical short is occurring in the fuel cell when supply of the fuel gas and the oxidization gas to the fuel cell is stopped; and scavenging means (12) for supplying a scavenging gas to the cathode side when it has been estimated that there is a possibility that the chemical short is occurring. |
| US08067126B2 |
Fuel cell, method for operating full cell and fuel cell system
A fuel cell, a method for operating a fuel cell and a fuel cell system, which ensure no dew condensation for a wet reaction gas in the inlet area of gas channels in plates in a fuel cell stack, are provided. Gas channels 2 and heat medium channels are disposed on one surface and the other surface of one plate 1, respectively. Gas channels are disposed on the other plate such that they face the gas channels 2 in the plate 1. A gas inlet header 3 is disposed at the upper part of the gas channel 2 in the plate 1 and a heat medium inlet header is disposed at the upper part of the heat medium channels such that they face the gas inlet header on the other side. Cooling water such as heat medium is supplied from the heat medium supply manifold hole 7 to the heat medium inlet header, thereby warming up the same. The water vapor in the reaction gas (wet fuel gas) is prevented from being condensed in the inlet area of the gas channels 2 by heating up the gas inlet header by the heat conduction. |
| US08067124B2 |
Fuel cell system
A fuel cell system for removing sulfur compounds adsorbed on the surfaces of a catalyst. The fuel cell system includes a fuel cell in which a plurality of unit cells, each having an electrolyte membrane held between electrode catalyst layers, are stacked, and a control device for recovering catalytic activity of the electrode catalyst layers by increasing an amount of water discharged from the electrode catalyst layers to a predetermined amount or more. |
| US08067119B2 |
Non-aqueous electrolyte secondary battery
A non-aqueous electrolyte secondary battery of the present invention includes a positive electrode including an active material absorbing and desorbing lithium ions, a negative electrode including an active material absorbing and desorbing lithium ions, a separator interposed between the positive electrode and the negative electrode, and a non-aqueous electrolyte. The separator includes a material containing a substituent group with electron-withdrawing property. The non-aqueous electrolyte includes a non-aqueous solvent and a solute dissolved therein, and the non-aqueous solvent includes at least one selected from the group consisting of a fluorine-containing aromatic solvent, a fluorine-containing cyclic carbonic acid ester, and a fluorine-containing cyclic carboxylic acid ester.The combination of the foregoing separator and the foregoing non-aqueous electrolyte makes it possible to suppress the deterioration in the rate performance of the battery even when the battery is stored under high voltage and high temperature. |
| US08067117B2 |
Cathode materials for secondary (rechargeable) lithium batteries
The invention relates to materials for use as electrodes in an alkali-ion secondary (rechargeable) battery, particularly a lithium-ion battery. The invention provides transition-metal compounds having the ordered-olivine or the rhombohedral NASICON structure and the polyanion (PO4)3 as at least one constituent for use as electrode material for alkali-ion rechargeable batteries. |
| US08067114B2 |
Electrolyte for lithium secondary battery of improved low-temperature property and secondary battery containing the same
Provided is a lithium secondary battery which uses a lithium manganese metal oxide as a cathode active material and a non-graphitic carbon material as an anode active material, and based on the total weight of the electrolyte, contains 0.1 to 20% by weight of a salt represented by Formula I in a lithium salt-containing non-aqueous electrolyte: R4X+YZn− (I) wherein R, X, Y, Z and n are as defined in the specification. The lithium secondary battery of the present invention can improve low-temperature properties of the battery by increasing the lithium ion-electrode reactivity and decreasing the electrode-interface resistance, via the formation of a charge double layer at the cathode-anode interface upon charging/discharging of the battery at a low temperature, and therefore can be preferably used in medium/large battery systems such as power sources for electric vehicles (EVs) and hybrid electric vehicles (HEVs) requiring operation under severe conditions. |
| US08067109B2 |
Battery holder
A battery holder for a button-type battery (1) includes a holder body having a base wall (100) thereof for receiving the battery, and positive and negative terminals (20, 30) assembled to the holder body. The negative terminal has short and long spring elements (311, 315) defining first and second supporting point (311A, 315B) respectively, such that in an initial released position, the button-type battery is lifted up by the first and second supporting points bearing against the base wall, and in a fully released position, that battery is lifted by the second supporting point against the base wall with the first supporting point leaving away from the base wall. The above spring elements provides two-stage elastic forces, for ease of the user to release the battery from the battery holder. |
| US08067103B2 |
Optical articles with thin hydrophobic layers
Optical articles such as ophthalmic lenses containing a thin hydrophobic surface layer of a fluorinated material adsorbed thereon are disclosed. |
| US08067102B2 |
Absorption type multi-layer film ND filter
In an absorption type multi-layer film ND filter having a thin substrate and provided thereon first and second absorption type multi-layer films which attenuate transmitted light, the first and second absorption type multi-layer films are constituted of multi-layer films each consisting essentially of dielectric layers formed of SiO2, Al2O3 or a mixture of these and metal film layers formed of Ni alone or an Ni alloy; the layers being alternately layered on the substrate; and the first and second absorption type multi-layer films are so formed on one side and the other side, respectively, of the substrate as to have a film structure in which they are symmetrical to each other interposing the substrate between them, and the warpage of the substrate has been controlled at a curvature of radius of 500 mm or more. |
| US08067099B2 |
Phosphorescent material, and organic electroluminescent device and image display apparatus using same
Provided is an organic electroluminescent device which has a high efficiency and high durability. The organic electroluminescent device includes an anode and a cathode; and a layer including an organic compound interposed between the anode and the cathode, in which the layer includes a phosphorescent material including an Ir complex or Pt complex having at least one ligand represented by any one of the following general formulae (1) to (4): |
| US08067088B2 |
Pelletized brominated anionic styrenic polymers and their preparation and use
Despite the frangibility of additive-free granules of brominated anionic styrenic polymer, pellets of unadulterated brominated anionic styrenic polymer are provided having 50 wt % or more bromine content, in which 70 wt % or more of the pellets are retained on a US No. 40 sieve and no more than 30 wt % are retained on a US No. 5 sieve. These pellets contain no binding agent and they do not break apart or revert to small particles and finely divided powder, typically called “fines” when subjected to ordinary handling. More specifically, no more than about 5 wt %, preferably no more than about 3 wt %, and more preferably no more than about 1 wt % of these pellets as formed and packaged are fines or dusts that can pass through a US No. 40 sieve. |
| US08067087B2 |
Heat seal adhesive paper product, method for manufacturing, and laminate product
A heat seal adhesive paper product is provided according to the invention. The heat seal adhesive paper product comprises a paper substrate and a heat activatable adhesive. The heat activatable adhesive comprises a result of applying an aqueous polymer dispersion to the paper substrate to form a coated paper substrate and drying the coated paper substrate. The aqueous polymer dispersion includes a polymer component having a melting temperature (Tm) greater than about 220° F. and a glass transition temperature (Tg) greater than about 50° F. A method for manufacturing a heat seal adhesive paper product is provided and a laminate product containing the heat seal adhesive paper product is provided. |
| US08067083B2 |
Surface ornamental structure of an article and a method for ornamentally working the surface structure of the article
An article surface ornamental structure that is easy to work and able to form a decorative pattern of an optional design and a high-grade feeling produced thanks to the metallic luster and, if necessary, to form a third dimensional decorative pattern. A metal-coated layer is formed by depositing a metal material with metallic luster on a surface of a base material. The metal-coated layer is at least partly provided with a separation part, in which the based material has its surface exposed to create an ornamental pattern thanks to a difference between the outer appearance of the base material and the metallic luster of the remaining metal-coated layer. With the base material and the metal-coated layer exposed, respectively, each of their surfaces is coated with a clear-coating layer made of synthetic resin material having transmittancy in order to protect the surface of the ornamental pattern. |
| US08067082B2 |
White film and backlight using same
A white film including polymer film wherein both the thermal shrinkage rate in the longitudinal direction and that in the transverse direction of the film are not less than −0.2% and not more than 0.5% at 90° C., and a backlight for liquid crystal displays using such a white film. Since the white film hardly suffers from undulation or rise in its end portions, it is most suitable as a reflection film for backlights of liquid crystal displays. Since a backlight for liquid crystal displays using this white film can be used for a long time, it is applicable to liquid crystal displays of various electrical/electronic devices. |
| US08067081B2 |
Screen, projection system, front projection television receiver, and screen manufacturing method
A screen includes: a reflection surface which reflects projection light, wherein a plurality of convexes are disposed on the reflection surface, and each of the convexes contains a spherical surface having a ¼ spherical shape, a curved surface having curvature larger than curvature of the spherical surface and disposed along an end of the spherical surface, and a cover surface having a flat surface shape and disposed at an end of the curved surface. |
| US08067080B2 |
Optical recording medium
Provided is an optical recording medium including, in sequence: a first substrate; a first information recording layer; an intermediate layer; a second information recording layer; and a second substrate having wobble convex portions on its surface, wherein information is recorded on or reproduced from the first information recording layer and second information recording layer by irradiation with a laser beam from a first information recording layer side, wherein the second information recording layer includes, over the second substrate, a light reflective layer, a dye recording layer, and an inorganic protective layer, wherein the inorganic protective layer has a thickness of 3 nm to 40 nm, and wherein the dye recording layer includes a cyanine compound expressed by General Formula (I) and a squarylium compound expressed by General Formula (II): |
| US08067079B2 |
Optical storage medium comprising a mask layer with a super resolution near field structure
The optical storage medium according to the invention uses a mask layer as a super resolution near field structure, which comprises a doped semiconductor material. The semiconductor material is n-doped particularly such that the reflectivity of the semiconductor material is increased, when irradiated with a laser beam. As a semiconductor material advantageously an indium alloy and as a doping material selenium or tellurium can be used. For the manufacturing of a respective optical storage medium a sputtering method for depositing the doped semiconductor material as the mask layer can be used, wherein the dopant is included already in the semiconductor sputtering target. |
| US08067078B1 |
Nacre composites, methods of synthesis, and methods of use
The present invention relates to a novel composite structure with enhanced toughness, which incorporates features mimicked from nacre (mother of pearl). The structure can be used in many industrial and clinical applications, including aeronautics (aircraft skin), the defense industry (armor materials); orthopedics and medical devices (tough, biocompatible coatings on prostheses) and micro-electro-mechanical systems (MEMS; increased reliability for critical components). |
| US08067076B2 |
Duplex capable paper backed transparencies
A paper backed transparency includes a transparency, a paper backing for the transparency and a first adhesive along a leading edge of the paper backed transparency. A second adhesive along a trailing edge of the paper backed transparency is disclosed to limit movement between the transparency and the paper backing during duplexing. |
| US08067075B2 |
Multilayer tube
A multilayer tube including at least three layers including a layer (a) formed of (A) polyamide 11 and/or polyamide 12, a layer (b) formed of (B) a polyamide (semi-aromatic polyamide) including a dicarboxylic acid unit containing a terephthalic acid and/or naphthalenedicarboxylic acid unit in a proportion of 50 mol % or more based on all dicarboxylic acid units, and a diamine unit containing an aliphatic diamine unit having a carbon number of 9 to 13 in a proportion of 60 mol % or more based on all diamine units, and a layer (c) formed of (C) a fluorine-containing polymer having introduced into the molecular chain thereof a functional group having reactivity with a polyamide-based resin, is provided as a multilayer tube excellent in an alcohol gasoline permeation-preventing property, interlayer adhesion, low-temperature impact resistance, heat resistance and chemical resistance. |
| US08067069B2 |
Strontium-substituted apatite coating
An implantable article including a biocompatible substrate and a bioactive strontium-substituted calcium phosphate ceramic apatite coating chemically bonded to at least a portion of the surface of the biocompatible substrate, wherein the strontium-substituted calcium phosphate ceramic apatite coating includes nanopores, nanocrystals and strontium ions, and includes a hexagonal crystal structure of apatite having a molar ratio of strontium ions to calcium ions of about 0.0001 to about 0.5, and the strontium ions inhibit bone resorption in vitro and enhance bone formation in vivo so that the implantable article exhibits enhance fixation and bone ingrowth in and around the implantable article. |
| US08067068B2 |
Liquid crystal compositions
This invention relates to liquid crystal compositions, and polymer networks and articles comprising the compositions. The compositions comprise at least one compound of the group of compounds represented by the structures of each of the following Formulas (IV), (V) and (VI), as defined herein. A process for making the composition is also provided. |
| US08067066B2 |
Tie-coat composition comprising at least two types of functional polysiloxane compounds and a method for using the same for establishing a coating on a substrate
The present invention relates to tie-coat compositions for fouling-release paint systems. The invention provides a method of coating a substrate with a coating composition comprising at least two types of functional polysiloxane compounds selected from epoxy-functional polysiloxanes, amino-functional polysiloxanes, and particular adhesion promoting agents of the polysiloxane type. The present invention also provides a substrate coated with such a composition and a composition particularly useful for said method. The binder phase may also comprise constituents of epoxy paint compositions, e.g. epoxy resins and amine curing agents. The compositions are particularly relevant in combination with diorganopolysiloxane-based fouling-release coatings and anticorrosive epoxy primer coatings. |
| US08067065B2 |
Fibrillar, nanotextured coating and method for its manufacture
A fibrillar, nanotextured coating is deposited on a substrate by contacting the substrate with a reaction mixture comprising a reagent which is hydrolyzable to produced a cross-linked reaction product, and a first solvent which solvates the reagent and the reaction product. The reagent is hydrolyzed so as to provide a cross-linked reaction product which is bonded to the substrate. The substrate is then contacted with a second solvent which is a non-solvent for the reaction product so as to cause nanoscopic phase separation of the reaction product, resulting in the formation of a fibrillar nanotextured coating which is bonded to the substrate. The thus produced coating may be subjected to further chemical modification. The method may be utilized to produce superhydrophobic coatings. Also disclosed are coatings made by the method of the present invention. |
| US08067063B2 |
Stretch composites and methods of making the composite
A stretch composite having one or more elastomeric members disposed on at least one region of an extensible fibrous substrate to provide stretch properties to a targeted region of the substrate. The composite has been incrementally stretched to at least partially break up the structure of the substrate in order to reduce its resistance to stretch. The stretch composites are useful for disposable and durable articles, such as disposable absorbent articles including diapers, pull-on diapers, training pants, incontinence briefs, catamenial garments, baby bibs, and the like, and durable articles like garments including sportswear, outerwear and the like. The present invention also relates to methods of forming such stretch composites. |
| US08067062B2 |
Carbon nano tube electrode formed by directly growing carbon nano tube on surface of carbon paper and supporting platinum-based nano catalyst on carbon nano tube using CVD method and manufacturing method thereof
A platinum-based nano catalyst supported carbon nano tube electrode and a manufacturing method thereof, more particularly to a manufacturing method of a carbon nano tube electrode and a carbon nano tube electrode supported with the platinum-based catalyst by growing the carbon nano tube on the surface of the carbon paper and using a CVD method on the surface of the carbon nano tube. By growing the carbon nano tube directly, the broad surface area and excellent electric conductivity of the carbon nano tube can be utilized maximally, and especially, the nano catalyst particles with minute sizes on the surface of the carbon nano tube by using the CVD method as a supporting method of the platinum-based catalyst on the surface of the carbon nano tube, the amount of the platinum can be minimized and still shows an efficient catalyst effect and by improving the catalyst activity by increasing the distribution, so academic and industrial application in the future is highly expected. |
| US08067061B2 |
Reaction apparatus having multiple adjustable exhaust ports
A reaction apparatus for a semiconductor fabrication apparatus, wherein the reaction apparatus includes at least two adjustable outlet ports for withdrawing reactant gases from the reaction chamber. Adjustment of the flow rate through each of the outlet ports selectively modifies the flow pattern of the reactant gases within the reaction chamber to maintain a desired flow pattern therewithin, such as a substantially uniform flow over the surface of a substrate being processed, and/or minimization of turbulence within the reactor. |
| US08067059B2 |
Hydrophobic composites and particulates and applications thereof
Novel hydrophobic composites, particularly hydrophobic particulates and free-flowing hydrophobic aggregates and methods utilizing same are disclosed. |
| US08067058B2 |
Method for producing battery electrode and apparatus for producing battery electrode
The amount of a paint for forming a porous heat-resistant layer supplied to the outer surface of a gravure roll is adjusted by removing the paint with a blade that is disposed so as to contact the outer surface. A resin blade is used, and the position at which the resin blade contacts the outer surface of the gravure roll is changed as the resin blade wears away. This prevents the amount of the paint for forming the porous heat-resistant layer removed from the outer surface of the gravure roll from changing as the resin blade wears away, so that the excess amount of the paint carried on the outer surface of the gravure roll is removed with good accuracy. An almost constant amount of the paint is thus transferred to an electrode surface from the outer surface of the gravure roll, and a porous heat-resistant layer with an almost uniform thickness is stably formed on an industrial scale. |
| US08067055B2 |
Drug-delivery endovascular stent and method of use
A radially expandable, endovascular stent designed for placement at a site of vascular injury, for inhibiting restenosis at the site, a method of using, and a method of making the stent. The stent includes a radially expandable body formed of one or more metallic filaments where at least one surface of the filaments has a roughened or abraded surface. The stent may include a therapeutic agent on the abraded surface. |
| US08067054B2 |
Stents with ceramic drug reservoir layer and methods of making and using the same
A method of making a drug eluting stent comprises forming a porous stent body surface layer by ion implantation, applying a layer of ceramic particles on the porous layer and compressing the layer of ceramic particles. The layer of ceramic particles can be compressed to successively higher densities. Drugs can be loaded into the layer of ceramic materials at a relatively low density before the layer of ceramic materials is compressed to a higher density to achieve a desired low drug release rate. |
| US08067053B2 |
Method for selective immobilization of macromolecules on self assembled monolayer surfaces
Disclosed is a method for selective chemical binding and immobilization of macromolecules on solid supports in conjunction with self-assembled monolayer (SAM) surfaces. Immobilization involves selective binding of peptides and other macromolecules to SAM surfaces using reactive landing (RL) of mass-selected, gas phase ions. SAM surfaces provide a simple and convenient platform for tailoring chemical properties of a variety of substrates. The invention finds applications in biochemistry ranging from characterization of molecular recognition events at the amino acid level and identification of biologically active motifs in proteins, to development of novel biosensors and substrates for stimulated protein and cell adhesion. |
| US08067051B2 |
Process for milling cocoa shells
A process for preparation of milled cocoa shell including grinding cocoa shell in a single unit operation in a short-duration manner without the need for moving mechanical parts. The milled cocoa shell product obtained from the grinding treatment has reduced heat degradation and avoids equipment maintenance concerns otherwise associated with mechanical milling of the cocoa shells while providing an edible granular product useful for food manufacture such as chocolate food production. |
| US08067040B2 |
Cinnamomi and poria composition and uses thereof
A composition comprising Chinese herbal medicines Ramulus cinnamomi and Poria cocos is provided, wherein the composition is defined by a fingerprint profile obtained from an improved chromatographic method. Various uses of such compositions are also provided. |
| US08067036B2 |
Gnetum extract
Gnetum extract which can be obtained from Gnetum fruit or Gnetum seeds that provide antimicrobial action and antioxidative effect (radical scavenging action) without carrying out special operation. The relevant Gnetum extract has various physiological (pharmacological) actions and can be used as active ingredients of foods , nourishments (nutritional supplements), medicines, cosmetics, etc. In addition, Gnetum extract is obtained by immersing sliced or ground Gnetum fruit or Gnetum seeds in water or water containing organic solvent and aging. |
| US08067034B2 |
Functional food for ameliorating endogenous melatonin secretion rhythm and functional food for ameliorating circadian rhythm
Disclosed are agents for phase-adjusting or enhancing the amplitude of an endogenous melatonin secretion rhythm and for improving a circadian rhythm, as well as functional food containing such an agent, which may prevent or ameliorate various symptoms, such as sleep disorder or prolonged sleep latency. The agent contains whey as the active component. |
| US08067032B2 |
Method for preparing submicron particles of antineoplastic agents
The present invention is concerned with the formation of submicron particles of an antineoplastic agent, particularly paclitaxel, by precipitating the antineoplastic agent in an aqueous medium to form a pre-suspension followed by homogenization. Surfactants with phospholipids conjugated with a water soluble or hydrophilic polymer such as PEG are used as coating for the particles. The particles produced generally have an average particle size of less than about 1000 nm and are not rapidly soluble. |
| US08067031B2 |
Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use
Crosslinkable compositions are provided that readily crosslink in situ to provide crosslinked biomaterials. The composition contains at least two biocompatible, non-immunogenic components having reactive groups thereon, with the functional groups selected so as to enable inter-reaction between the components, i.e., crosslinking. In one embodiment, a first component has nucleophilic groups and a second component has electrophilic groups. Additional components may have nucleophilic or electrophilic groups. Methods for preparing and using the compositions are also provided as are kits for delivery of the compositions. Exemplary uses for the crosslinked compositions include tissue augmentation, biologically active agent delivery, bioadhesion, and prevention of adhesions following surgery or injury. |
| US08067030B2 |
Controlled release composition and method of producing the same
A controlled release composition containing a physiologically active substance in high content, suppressing the initial excess release, and achieving a stable release speed over a long period of time is provided.A controlled release composition comprising (1) a physiologically active substance or salt thereof in an amount of about 14% (w/w) to about 24% (w/w) based on the total composition weight, (2) hydroxynaphthoic acid selected from the group consisting of 3-hydroxy-2-naphthoic acid and 1-hydroxy-2-naphthoic acid or salt thereof, and (3) a lactic acid polymer or salt thereof having a weight-average molecular weight of 15000 to 50000 in which the content of polymers having molecular weights of 5000 or less is about 5% by weight or less, wherein the molar ratio of said hydroxynaphthoic acid or salt thereof to said physiologically active substance or salt thereof is from 3:4 to 4:3. |
| US08067027B2 |
Tissue augmentation material and method
A material and method for augmenting soft tissue. The tissue augmentation material consists essentially of water and a polysaccharide gel former selected from the group consisting of a cellulose polysaccharide, starch, chitin, chitosan, hyaluronic acid, hydrophobe modified polysaccharide, an alginate, a carrageenan, agar, agarose, an intramolecular complex of a polysaccharide, an oligosaccharide and a macrocylic polysaccharide. Glycerin may also be included. The material may be used to augment soft tissue in a variety of areas, including the facial region and vocal folds. |
| US08067025B2 |
Nitric oxide generating medical devices
Medical devices having a catalyst capable of catalyzing the generation of nitric oxide attached to the medical device and methods of treating a vascular condition using the devices are provided. |
| US08067021B2 |
Methods and compositions for delivery of growth factor to fibrous connective tissue
The presently disclosed subject matter relates to a peptide composition for non-covalently localizing fibrous connective tissue-inducing growth factor to a surface of an implant, the composition comprising a peptide having binding affinity for a surface material of an implant coupled to a peptide having binding affinity for a fibrous connective tissue-inducing growth factor. Methods are provided for delivering fibrous connective tissue-inducing growth factor GDF-7 in an amount effective to promote fibrous connective tissue repair and fibrous connective tissue formation. Also provided are methods of applying the peptide composition to an implant by contacting the composition with a surface of the implant; and kits comprising the compositions. |
| US08067020B2 |
Sustained release formulation
A composition comprises a protein, a polyol, and a metal. The protein is stabilized by the polyol and the metal, and is protected from denaturing when in contact with an organic solvent. The polyol may be a hydrocarbon containing two or more hydroxyl groups (—OH) bonded to carbon. The metal may be divalent. |
| US08067016B2 |
Fusion proteins of Mycobacterium tuberculosis
The present invention relates to fusion proteins containing at least two Mycobacterium species antigens. In particular, it relates to nucleic acids encoding fusion proteins that include two or more individual M. tuberculosis antigens, which increase serological sensitivity of sera from individuals infected with tuberculosis, and methods for their use in the diagnosis, treatment, and prevention of tuberculosis infection. |
| US08067014B2 |
Chimeric AAV capsid proteins
Recombinant adeno-associated viral (AAV) capsid proteins are provided. Methods for generating the recombinant adeno-associated viral capsid proteins and a library from which the capsids are selected are also provided. |
| US08067011B2 |
Compositions and methods for treating B-cell malignancies
The present invention provides a targeted multi-layered drug delivery system for the delivery of cytotoxic agents to B-cells. |
| US08067008B2 |
Peptide inhibitors for mediating stress responses
The present invention relates to peptides capable of inhibiting cellular and immune stress responses in a eukaryotic cell. The invention provides compositions and methods for the treatment of human degenerative diseases and inflammation, utilizing these peptides. |
| US08067006B2 |
Polymeric carriers of therapeutic agents and recognition moieties for antibody-based targeting of disease sites
The present invention concerns methods and compositions for delivery of therapeutic agents to target cells, tissues or organisms. In preferred embodiments, the therapeutic agents are delivered in the form of therapeutic-loaded polymers that may comprise many copies of one or more therapeutic agents. In more preferred embodiments, the polymer may be conjugated to a peptide moiety that contains one or more haptens, such as HSG. The agent-polymer-peptide complex may be delivered to target cells by, for example, a pre-targeting technique utilizing bispecific or multispecific antibodies or fragments, having at least one binding arm that recognizes the hapten and at least a second binding arm that binds specifically to a disease or pathogen associated antigen, such as a tumor associated antigen. Methods for synthesizing and using such therapeutic-loaded polymers and their conjugates are provided. |
| US08067002B2 |
Humanized anti-factor D antibodies
The invention relates to humanized anti-human Factor D monoclonal antibodies, their nucleic acid and amino acid sequences, the cells and vectors that harbor these antibodies and their use in the preparation of compositions and medicaments for treatment of diseases and disorders associated with excessive or uncontrolled complement activation. These antibodies are useful for diagnostics, prophylaxis and treatment of disease. |
| US08067001B2 |
Antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof
An antibody of the invention interacts with human DR5 to produce agonistic or antagonistic effects downstream of the receptor including inhibition of cell proliferation and apoptosis. Nucleic acid sequences and amino acid sequences of anti-DR5 antibodies have been elucidated and vectors and cells containing and expressing these sequences have been generated. Methods and uses for the antibodies are detailed including treatment of apoptosis-related disease and treatment of dysregulated cell growth. |
| US08067000B2 |
Cancer treatment with endothelin receptor antagonists
The present invention relates to therapeutic protocols and pharmaceutical compositions designed to treat and prevent cancer. More specifically, the present invention relates to a novel method of treating cancer using antagonists to the endothelin B receptor (ETB) or inactive mimic forms of endothelin-1. The pharmaceutical compositions of the invention are capable of selectively inhibiting the early events associated with the development of cancer. The present invention further relates to screening assays to identify compounds which inhibit ETB activation. |
| US08066999B2 |
PEGylated Aβ fab
A method to treat conditions associated with Aβ peptide activity both prophylactically and therapeutically is described. The method employs humanized antibody fragments that specifically bind human Aβ peptide between amino acid positions 13-28, wherein the antibody fragments are covalently attached to a polyethylene glycol (PEG) molecule. |
| US08066997B2 |
Modulation of activity of neurotrophins
The present invention relates to methods for modulating the activity of one or more neurotrophins, such as neural growth factor (NGF), brain derived neurotrophic factor (BDNF), neurotrophin-3, and neurotrophin-4 (NT-4), in an animal and methods for treatment of a disease or disorder in an individual by modulation of neurotrophin activity. The modulation is carried out by interfering with binding between a neurotrophin and a receptor of the Vps10p-domain receptor family or modulating the expression of a receptor of the Vps10p-domain receptor family. Methods for screening for agents capable of modulating neurotrophin activity and agents selected using these screening methods are also disclosed, as are methods for determining the effect of an agent on one or more neurotrophins in cells. The present invention also pertains to methods for modulating the transport of one or more neurotrophins. |
| US08066996B2 |
Anti-CCR7 receptor antibodies for the treatment of cancer
Antibodies, or antigen-binding fragment thereof, which bind to a CCR7 receptor are capable of selectively killing, impairing migration and/or blocking dissemination of tumor cells expressing a CCR7 receptor. Use of said antibodies for killing or for inducing apoptosis of said tumor is disclosed, thus providing an alternative therapy for treatment of cancer which tumor cells express a CCR7 receptor. |
| US08066993B2 |
Use of ventricular enlargement rate in intravenous immunoglobulin treatment of Alzheimer's disease
The present invention relates to the use of MRI monitoring of ventricular enlargement rate as an objective measure for the purpose of assessing disease progression in patients suffering from Alzheimer's disease and for the purpose of determining therapeutic effectiveness of a treatment regimen for Alzheimer's patients. Methods for treating Alzheimer's Disease and monitoring therapeutic effectiveness are provided. |
| US08066992B2 |
Medicament and a method of treating a pathological syndrome
A medicament based on antibodies contains an activated form of monoclonal, polyclonal, or natural antibodies to interferon in low or ultra-low doses prepared by multiple consecutive dilutions and exposure to external factors, preferably in accordance with homeopathic technology. In order to obtain antibodies, human or heterologous interferon alpha, beta, or gamma, including recombinant interferon, is used; a mixture of various, mostly centimal, homeopathic dilutions being employed. A method of treating a pathologic syndrome, whose formation is affected by interferon, consists in the use of activated forms of antibodies to interferon alpha, beta, or gamma in low or ultra-low doses obtained by multiple consecutive dilutions and exposure to external factors. |
| US08066985B2 |
Reovirus for the treatment of cellular proliferative disorders
Methods for treating proliferative disorders, by administering reovirus to a Ras-mediated proliferative disorder, are disclosed. The reovirus is administered so that it ultimately directly contacts ras-mediated proliferating cells. Proliferative disorders include but are not limited to neoplasms. Human reovirus, non-human mammalian reovirus, and/or avian reovirus can be used. If the reovirus is human reovirus, serotype 1 (e.g., strain Lang), serotype 2 (e.g., strain Jones), serotype 3 (e.g., strain Dearing or strain Abney), as well as other serotypes or strains of reovirus can be used. Combinations of more than one type and/or strain of reovirus can be used, as can reovirus from different species of animal. Either solid neoplasms or hematopoietic neoplasms can be treated. |
| US08066977B2 |
Agent for permanent hair waving containing heterocyclic mercapto compound
Disclosed is an agent for permanent hair waving that can realize permanent hair waving even in the neutral to weakly acidic pH range in which irritation particularly to the skin is not significant. The agent for permanent hair waving includes at least one heterocyclic mercapto compound represented by formula (1): wherein R1 and R2 each independently represent a hydrogen atom or an optionally substituted alkyl group having 1 to 5 carbon atoms; X represents —O—, —S—, —NH—, or —NR3—; R3 represents an alkyl group having 1 to 5 carbon atoms; n is an integer of 0 to 2; and, when n is 2, group SH may be attached to any carbon atom of an alkylene group having 2 carbon atoms. |
| US08066971B2 |
Targeting pulmonary epithelium using ADRP
This invention provides novel compositions and methods for the specific and/or preferential delivery of an effector (e.g. a drug or label) to an epithelial cell (e.g. a pulmonary epithelium). The compositions comprise an adipocyte differentiation-related protein (ADRP) attached to an effector thereby forming a chimeric moiety. The chimeric moiety is preferentially delivered to epithelial cells. |
| US08066968B2 |
X-ray-induced dissociation of H2O and formation of an O2-H2 alloy at high pressure
A novel molecular alloy of O2 and H2 and a method of producing such a molecular alloy are provided. When subjected to high pressure and extensive x-radiation, H2O molecules cleaved, forming O—O and H—H bonds. In the method of the present invention, the O and H framework in ice VII was converted into a molecular alloy of O2 and H2. X-ray diffraction, x-ray Raman scattering, and optical Raman spectroscopy demonstrate that this crystalline solid differs from previously known phases. |
| US08066964B2 |
Thermally exfoliated graphite oxide
A modified graphite oxide material contains a thermally exfoliated graphite oxide with a surface area of from about 300 m2/g to 2600 m2/g, wherein the thermally exfoliated graphite oxide displays no signature of the original graphite and/or graphite oxide, as determined by X-ray diffraction. |
| US08066961B2 |
Kinematic wellplate mounting method
A mechanism for positionally restraining a microplate is disclosed. The mechanism is defined by a base having at least one surface with a receptacle for the insertion of a microplate into the base. Supports and/or positioning structures on a surface of the base have point contacts to restrain movement of the microplate in a stable position for repeatable optical detection measurements. The supports and/or positioning structures permit insertion of the microplate for an initial measurement, removal of the microplate for analytical manipulation, and re-insertion of the microplate to an exact position so as to allow analysis of precise comparative measurements by an optical reader. |
| US08066960B2 |
Method and device for an accelerated oxidation test of fuels or petroleum products, as well as a computer program for controlling such a device, and a corresponding computer readable storage medium
A device and a method for an accelerated oxidation test of fuels or petroleum products, as well as a computer program for controlling such a device, and a corresponding computer readable storage medium, which are applicable, in particular, for the simulation of the aging of fuels or petroleum products. A device for an accelerated oxidation test of fuels or petroleum products is proposed, whereby the device comprises of a pressure vessel (1) to hold specimen (2) of fuels or petroleum products, and the pressure vessel (1) contains at least one device to change the temperature. A corresponding method provides that a specimen (2) of fuel or petroleum product is placed in a pressure vessel (1), the specimen is brought to a predefined temperature above 100° C. by at least one device to change the temperature, which is placed in the pressure vessel (1) and/or in the specimen (2), and the absolute pressure value is monitored so as to determine the oxidation. |
| US08066957B2 |
Easy strip access primary container and methods of manufacturing and utilization thereof
Embodiments of the present invention relate to a test strip container which provides easy access to test strips. The test strip container includes a lower housing, an upper housing, and a retaining member configured to releasably retain the test strips in a nested configuration. The nested configuration of the test strip container provides easy access to test strips by arranging the test strips so that they extend radially outward from the retaining member. The radial arrangement of the test strips operates to separate the test strips so that test strip users may easily select a single test strip from a plurality of test strips. Alternatively, the test strip container includes a lower housing, an upper housing, and a retaining member configured to releasably retain the test strips in a longitudinal configuration. |
| US08066952B2 |
Method for removing soot particles from an exhaust gas, associated collecting element and system
A method for removing soot particles from an exhaust gas of an internal combustion engine, especially of a diesel engine, includes feeding the exhaust gas through a collecting element through which the exhaust gas can pass freely but which is provided with a plurality of deflections and/or zones of swirl and calming or stabilization. At least a proportion of the particles are held or swirled around in the collecting element until there is a sufficient probability of reaction with nitrogen dioxide and a majority of the collected particles have been removed. A collecting element has flow channels through which the exhaust gas can pass freely. However, the flow channels are configured in such a way as to form deflections or zones of swirl and calming or stabilization. A system having the collecting element is also provided. |
| US08066951B2 |
Method for removing soot particles from an exhaust gas, associated collecting element and system
A method for removing soot particles from an exhaust gas of an internal combustion engine, especially of a diesel engine, includes feeding the exhaust gas through a collecting element through which the exhaust gas can pass freely but which is provided with a plurality of deflections and/or zones of swirl and calming or stabilization. At least a proportion of the particles are held or swirled around in the collecting element until there is a sufficient probability of reaction with nitrogen dioxide and a majority of the collected particles have been removed. A collecting element has flow channels through which the exhaust gas can pass freely. However, the flow channels are configured in such a way as to form deflections or zones of swirl and calming or stabilization. A system having the collecting element is also provided. |
| US08066950B2 |
Catalytic converter system and element for diesel engines
An improved exhaust system and catalytic converter element for a diesel engine wherein the improvement comprises: holding means for restricting the movement of catalytic converter elements in an overhead exhaust manifold; an improved catalytic converter element having at least one retaining rod extending through the catalyst substrate and/or having at least one retaining lip projecting into the substrate; a stabilizer projecting from the cover for the element insertion slot for receiving an end portion of the catalytic converter element to restrict the movement of the converter element in the exhaust manifold; perforated flow distribution elements provided upstream of the catalytic converter elements; and/or vertical coupling manifolds which each receive exhaust from a pair of engine cylinders and then deliver the combined exhaust stream to a separate one of the inlet openings in the bottom of the overhead exhaust manifold. |
| US08066947B2 |
Air scrubbing system
An air scrubber for eliminating an associated airborne contaminants and sterilizing air provided to protect against nocosomial infections, environmental allergens, weapons of biological and chemical attacks and operations requiring clean environment. The air scrubber includes a housing containing an alkali solution at pH 14 through which air passes and suspended liquid particles removed; provides are made for use in central air-conditioning systems, stand-alone applications and portable use along with respirators. |
| US08066945B2 |
Detection apparatus for biological materials and methods of making and using the same
Apparatus comprising a surface site comprising a substantially inorganic surface having a chemical composition selected from the group consisting of metals, semiconductors, insulators, and mixtures thereof, the surface positioned within a polypeptide bonding region and having a selective bonding affinity for a polypeptide; a plurality of interlayers between which the surface site is interposed; a distal site end on the surface site and distanced from the interlayers, the surface being provided on the distal site end; the surface site and the interlayers being interposed between first and second supports; first and second conductors provided on the first and second supports and having respective first and second distal conductor ends positioned within the polypeptide bonding region; the conductors being capable of applying an external voltage potential across the polypeptide bonding region. Apparatus, optionally comprising such first and second supports and conductors; and comprising a third conductor in electrical communication with the surface site, the third conductor positioned for electrical communication with a source of an external bias voltage. Techniques for making apparatus. |
| US08066936B2 |
Compliant fill tube assembly, fill tube therefore and method of use
A fill tube assembly is for a casting mold. The fill tube assembly includes a fill tube having a tubular member with a receiving end, a mold-engaging end and an intermediate portion. The mold-engaging end has a tapered flange radially extending therefrom, the remainder of the tubular member has a substantially, uniform cross-section. A clamping assembly is structured to maintain a substantially leakproof seal at the fill tube, casting mold interface while accommodating dimensional variations. The clamping assembly includes a gasket, a load ring, a clamping plate and a pre-load gap between the clamping plate and the casting mold and optionally includes a dimensional compensating ring. When tightened, the clamping plate biases the load ring against the flange thereby distributing a uniform load against the casting mold, compressing the gasket therebetween while narrowing the pre-load gap to accommodate dimensional variations. A method of use is also disclosed. |
| US08066935B2 |
Turbulence inhibiting impact well for submerged shroud or sprue poured castings
An impact well configured to reduce the turbulence in a flowing fluid. The impact well has the shape of a frustum and includes an upper portion, an intermediate portion and a base portion. The base portion includes a domed portion that extends upwards into the intermediate portion. The upper portion, the intermediate portion and the base portion each included stepped areas configured to assist in the alignment of the portions and the assembly of the well. |
| US08066933B2 |
Polymer powder comprising polyamide use thereof in a moulding method and moulded body made from said polymer powder
The present invention relates to a polymer powder which comprises polyamide, and to the use of this powder for shaping processes, and also to moldings produced from this polymer powder. The shaping processes are layer-by-layer processes which use powders, where regions of the respective layer are selectively melted via introduction of electromagnetic energy. The selectivity may—with no intention of restricting the invention thereto—be achieved via masks, application of inhibitors, of absorbers, or of susceptors, or via focusing of the energy introduced. After cooling, the regions then solidified can be removed in the form of moldings from the powder bed. |
| US08066931B2 |
Method and an apparatus for the manufacture of concrete pipes
A method and an apparatus for the manufacture of concrete pipes (2) made of an outer layer and having an inner layer of greater density in surface structure is described. The inner layer is applied by an applicator in a mould (1) having both outer (3) and inner (4) mould parts. The applicator is formed by an inner mould part or core (4) or by an applicator unit in immediate connection with the core (4). The applicator applies the inner layer simultaneously or immediately following vibration of the concrete forming the pipe. The inner layer is applied during movement of the inner mould part or core (4) in its longitudinal direction, the core having one or more supply openings (14) provided along the circumference of the core (4) at the upper end of the core (4) for supplying a further material of greater density to form the inner layer. |
| US08066928B2 |
Method of providing a moisture vapor barrier layer to a core of a golf ball
A method of forming a water vapor barrier layer to a core of a golf ball is provided. The method includes placing the core of the golf ball into a vapor barrier composition, withdrawing the lifting device, and spinning and optionally oscillating the core within the composition for a time sufficient for the composition to form a layer on the core. The present invention also provides an apparatus that can be used to form a water vapor barrier layer. |
| US08066926B2 |
Method of manufacturing reinforced medical tubing
Methods for manufacturing reinforced tubing suitable for medical device applications are disclosed. An inner layer is molded around a core to define an inner surface adjacent to the core and an outer surface opposite the inner surface. The outer surface includes one or more recessed pathways defined therein. A reinforcement member is then formed in each of the one or more recessed pathways of the molded inner layer. An outer layer including an inner surface and an outer surface is subsequently molded over the inner layer and the reinforcement member. The inner surface of the outer layer substantially conforms to the outer surface of the inner layer and the reinforcement member. The core is then removed from within the inner layer to provide a lumen through the inner layer. |
| US08066923B2 |
Poly(trimethylene terephthalate)/poly(alpha-hydroxy acid) biconstituent filaments
This invention relates to poly(trimethylene terephthalate)/poly(alpha-hydroxy acid) biconstituent filaments, methods for making the same and end uses thereof. |
| US08066921B2 |
Simultaneously blow molded container and closure
A method of producing a container and a closure comprises blow molding a body comprising a container portion and a closure portion joined together, and separating the closure portion from the container portion. A container and/or a closure produced according to the method are also disclosed, as well as an intermediate product for producing a container and a closure. |
| US08066920B2 |
Methods for controlling and enhancing the quality of base materials employed for the production of semi-finished ophthalmic lenses
Optical qualities of a production lot of base material used in the fabrication of semi-finished lenses may be accurately determined by employing chipper plate samples produced from the base material in accordance with aspects of the present invention. In various implementations of the present invention, the chipper plates samples may be fabricated by subjecting base material to an extended cycle time and temperature profile using a mold having cavities of different thicknesses. The resulting chipper plates provide an improved indication of the color of semi-finished lenses molded from the production lot as well as an improved indication of resin stabilizer defects that may be utilized during a pelletizing process to control and enhance the quality of a production lot. Furthermore, the chipper plates may be provided by suppliers as samples of a production lot to enable customers to base purchasing decisions on a reliable and accurate measure of optical properties. |
| US08066918B2 |
Apparatus for producing particles, emulsifier holding member, method for producing particles, and method for producing molecular membrane
The invention provides an apparatus for producing molecular membranes or particles, having a) a fluid supplying member configured to store a fluid, b) a plunger unit configured to extrude the fluid from the fluid supplying member, and c) an emulsifier holding member having at least two or more through-holes for holding an emulsifier, the through-holes allowing the fluid extruded from the fluid supplying member to pass therethrough, the emulsifier holding member being attachable to and detachable from the fluid supplying member. |
| US08066911B2 |
Method of improving flowability of adipic acid
A method of improving flowability of adipic acid includes adding to the adipic acid at a relatively low temperature a flowability improving agent, such as an acyclic saturated monobasic acid containing 10 to 22 carbon atoms or an acyclic saturated dibasic acid containing 10 to 14 carbon atoms. |
| US08066905B2 |
Optical element obtained by homeotropically orienting liquid crystal molecule, member for liquid crystal display device using the same, and liquid crystal display device
An object of the present invention is to provide an optical element which can suppress a production cost, has good heat resistance, uniformly maintains the fixed orientation of a liquid crystal polymer in a wide temperature range, shows a low haze with reliability, and can maintain desired birefringence property with reliability. The present invention relates to an optical element formed by forming, on an upper surface of a base material having light transmittance, at least a birefringence layer having a structure obtained by fixing liquid crystal monomers each having a polymerizable group at a terminal thereof in a state where the monomers are homeotropically oriented, and by removing an additive layer formed on the upper surface of the birefringence layer. |
| US08066904B2 |
Controlled generation of nitric oxide
Inhalation of low levels of nitric oxide can rapidly and safely decrease pulmonary hypertension in mammals. Precise delivery of nitric oxide at therapeutic levels of 20 to 100 ppm and inhibition of reaction of nitric oxide with oxygen to form toxic impurities such as nitrogen dioxide can provide effective inhalation therapy for pulmonary hypertension. |
| US08066903B2 |
Method for preparing a cellulose carbamate solution
A method for preparing a cellulose carbamate solution. Dissolving is performed in two steps, first by moistening cellulose carbamate pulp with a dilute alkaline solution and second by admixing a concentrated alkaline solution, as cold as possible, to the pulp under intensive stirring. The technique utilizes the low freezing point of the aqueous NaOH solution at the concentration of 18%, wherein the freezing point is below −20° C., and the intensive stirring function of the dissolve mixer device during the dosage. It is possible to prepare solutions of high quality and having high dry matter content in a mixing time of a few minutes only. |
| US08066899B2 |
Non-ignitable gaseous composition comprising difluoromethane and tetrafluoroethylene
The present disclosure relates to non-ignitable gaseous compositions comprising difluoromethane and tetrafluoroethylene. When the pressure is at least 150 psig, the molar percentage of tetrafluoroethylene in the non-ignitable gaseous composition is no more than 111.6−0.124X. When the pressure is less than 150 psig, the molar percentage of tetrafluoroethylene in the non-ignitable gaseous composition is no more than 102−0.06X. X is the pressure in the unit of psig.The present disclosure also provides processes for making such non-ignitable gaseous compositions.Also disclosed are azeotropic compositions of TFE and HFC-32. |
| US08066892B2 |
Method for manufacturing a perpendicular magnetic write head with a wrap around shield
A method for manufacturing a write pole for a perpendicular magnetic write head. The method employs a damascene process to construct the write pole with a very accurately controlled track width. The method includes depositing a layer of material that can be readily removed by reactive ion etching. This material can be referred to as a RIEable material. A mask is formed over the RIEable material and a reactive ion etching is performed to form a tapered trench in the RIEAble material. A CMP stop layer can the be deposited, and a write pole plated into the trench. A CMP can then be performed to define the trailing edge of the write pole. Another masking, etching and plating step can be performed to form a trailing, wrap-around magnetic shield. |
| US08066882B2 |
Column packing method
A method for packing a media bed in a column (3) from a slurry being a dispersion of said media particles and a liquid, said method comprising the steps of: a) estimating a slurry concentration; b) filling the column (3) with a certain volume of the slurry from a slurry tank (13) connected to the column; c) packing a test media bed from the slurry; d) detecting where the test media bed is consolidated; e) use the information about the consolidated test media bed height for providing to the column an amount of slurry that after further packing will give a user target bed height; f) packing a media bed from the slurry. |
| US08066879B2 |
Method for treating waste water
An apparatus and method for passively generating a current flow in a body of water is disclosed. The passive water circulating apparatus has an aeration plate having a central opening; a plurality of flotation members joined to the aeration plate, the plurality of flotation members being adapted and disposed for maintaining buoyancy of the aeration plate above a water surface; an uplift tube member having a central orifice in fluid communication with the central opening of the aeration plate; a concentrator member disposed at an end of the uplift tube opposite the aeration plate, the concentrator member having a bottom opening in fluid communication with an upper opening, the bottom opening being wider than the upper opening and the upper opening being connected to the uplift tube member; and a plurality of bio-substrates suspended from the concentrator member below the bottom opening, the plurality of bio-substrates providing a substrate for growth of microbes. |
| US08066871B2 |
Filtration system incorporating modular one-piece end caps
A hydraulic filter includes a canister extending along the longitudinal axis. A closed end cap is at one end of the canister for closing one end thereof. A removable filter element is contained within the canister and a modular one-piece input end cap is at an end of the canister. The one-piece input end cap includes a hydraulic input chamber and a hydraulic output chamber which can be positioned in any one of three mutually perpendicular directions. The one-piece input end cap also allows for sensors to be positioned in any one of three mutually perpendicular directions. In addition, the one-piece input end cap can be utilized in base-ported or top-ported configurations while also allowing for side-to-side or side-to-end configurations. |
| US08066870B2 |
Separation of tar from sand
A system for separating hydrocarbons from a solid source including a primary separation tank including a first hydrocarbon removing device to remove hydrocarbons from a slurry of water and solids. Further, the system including a transfer device between the primary separation tank and a secondary separation tank, wherein the transfer device is configured to transfer solids from the slurry to the secondary separation tank. Further still, the system including a second hydrocarbon removal device, a fine particle separation device to remove remaining solids in the secondary separation tank, and a product collection tank to receive hydrocarbons removed from the primary and secondary separation tanks. |
| US08066866B2 |
Methods for measuring physiological fluids
Electrochemical measurement techniques for measuring the concentration of an analyte in a physiological fluid sample are described. More particularly, the present invention relates to techniques for distinguishing a signal caused by an extraneous event from a desired information providing signal such as one indicative of a measurement error. |
| US08066864B2 |
Crosslinked polymers, galvanization baths comprising them and use thereof
The invention relates to polymers which comprise at least partially cross-linked main chains constructed from repeat units of the general formula I and possibly repeat units of the general formula II and also possibly repeat units comprising five- or six-membered aza aromatics or nitrogen-containing heterocycles. Polymers of this type are used as additive in electroplating baths since these enable a better layer thickness distribution of the electroplated layer. |
| US08066863B2 |
Electrodeposition technique and apparatus to form selenium containing layers
A multi step process, which forms a Group VIA material layer, such as a selenium (Se) layer, having a thickness greater than 500 nanometers. The process includes electroplating a Se material layer, which has an amorphous micro-structure and which exhibits high electrical resistivity, on a workpiece and subsequently annealing the Se layer. Annealing process transforms the amorphous structure of the Se layer into a crystalline structure which is conductive. After the annealing, another Se layer can be electroplated onto the annealed Se layer. The electroplating and annealing steps can be repeated until the desired Se layer thickness is reached. |
| US08066859B2 |
Electrochemical carbon monoxide sensor supervision
A sensor supervision system for periodically providing a test to accesses the status of a gas detection sensor, such as a carbon monoxide (CO) sensor, is provided. To access the status of the CO sensor, a processor provides a voltage to the sensor supervision system, such that a voltage is applied to CO sensor, charging the CO sensor. The status of the CO sensor is accessed by determining the change in the voltage charge of the CO sensor between two sampling time points. If the first sample voltage is substantially equal to the second sample voltage, i.e., a substantially constant voltage, the carbon monoxide sensor fails the test. However, if there is an change is the voltage change between the first and second sampled time points, the CO sensor passes the test. |
| US08066857B2 |
Shaped anode and anode-shield connection for vacuum physical vapor deposition
A physical vapor deposition apparatus includes a vacuum chamber with side walls, a cathode, a radio frequency power supply, a substrate support, a shield, and an anode. The cathode is inside the vacuum chamber, and the cathode includes a sputtering target. The radio frequency power supply is configured to apply power to the cathode. The substrate support is inside and electrically isolated from the side walls of the vacuum chamber. The shield is inside and electrically connected to the side walls of the vacuum chamber. The anode is inside and electrically connected to the side walls of the vacuum chamber. The anode includes an annular body and an annular flange projecting inwardly from the annular body, and the annular flange is positioned to define a volume below the target for the generation of plasma. |
| US08066856B2 |
Service module with at least one anode clamp and means for applying a force or a shock on the anode rod
A tending module for a series of electrolysis cells designed for the manufacture of aluminum by igneous electrolysis, each cell including a series of anodes provided with a metal rod designed to fix and electrically connect the anodes to a metal anode frame. The tending module includes a frame to be fixed to a mobile component, and at least one anode handling unit connected to the frame. The module also includes, integral with the anode handling unit, an activator that can exert at least one force or impulse on the anode rod, with a force such that, although the stem is firmly maintained in contact against the anode frame, the contact surfaces are moved in relation to each other by an amount sufficient for electrical contact to be improved. Advantageously, the activator is a jack or an impulse generator integral with the anode clamp. |
| US08066853B2 |
Method of forming inorganic alignment film, inorganic alignment film, substrate for electronic device, liquid crystal panel and electronic apparatus
A method of forming an inorganic alignment film made substantially of an inorganic material on a base substrate is provided comprising a milling process of irradiating ion beams onto the surface of the base substrate, on which the inorganic alignment film is to be formed, from a direction inclined at a predetermined angle θb with respect to a direction vertical to the surface, and a film-forming process of forming the inorganic alignment film on the base substrate onto which the ion beams are irradiated. In the milling process, the predetermined angle θb is preferably 2° or more. In the milling process, an acceleration voltage of the ion beams during the irradiation of the ion beams is preferably 400 to 1400 V. |
| US08066847B2 |
Creping adhesives comprising blends of polyaminoamide epihalolhydrin resins and polyamides
A composition comprising one or more polyaminoaminde epihalohydrin resins and one or more polyamides in a ratio of about 1:99 to about 99:1 based on polymer actives and use of the composition for creping paper webs. |
| US08066845B2 |
Compact wastewater concentrator using waste heat
A compact and portable liquid concentrator includes a gas inlet, a gas exit and a flow corridor connecting the gas inlet and the gas exit, wherein the flow corridor includes a narrowed portion that accelerates the gas through the flow corridor. A liquid inlet injects liquid into the gas stream at a point prior to the narrowed portion so that the gas-liquid mixture is thoroughly mixed within the flow corridor, causing a portion of the liquid to be evaporated. A demister or fluid scrubber downstream of the narrowed portion removes entrained liquid droplets from the gas stream and re-circulates the removed liquid to the liquid inlet through a re-circulating circuit. Fresh liquid to be concentrated is also introduced into the re-circulating circuit at a rate sufficient to offset the amount of liquid evaporated in the flow corridor. |
| US08066841B2 |
Method for manufacturing composite systems made of metal polymer shaped parts
The disclosure relates to a method for manufacturing composite systems comprising metal and polymer shaped parts in the form of stabilizers, bushings, axle bearings, especially in the chassis area, stops, buffers, especially for supporting arms for aggregate bearings, or sleeve bearings, especially torsion-bar shoulder bearings, wherein at least one completely vulcanized or partially vulcanized elastomer shaped part, especially a rubber shaped part, as the polymer shaped part and at least one metal part are first prepared, the metal part and the polymer shaped part are then brought into abutment against one another, at least in parts and finally the metal part or at least one region of the surface on which the metal part and the polymer shaped part abut against one another, is at least temporarily exposed to at least one induction field or at least one inductive heating unit. |
| US08066840B2 |
Finger pattern formation for thin film solar cells
A method of forming metallic connector patterns for solar cells, whereby an embosser having raised features shaped in the form of a metallic connector pattern is used to attach a portion of a metallic foil to a transparent conductive layer formed on a top transparent surface of a solar cell structure. The raised surfaces of the embosser press the metallic foil portion against the transparent conductive layer. Heat and pressure directed to the metallic foil portion attach the metallic foil portion to the underlying transparent conductive layer, and then the rest of the metallic foil, which is not attached to the transparent conductive layer, is removed. |
| US08066838B1 |
Composite tubes and method of manufacturing same
A method of fabricating a composite tubular member includes providing a mandrel having a central longitudinal axis and wrapping a plurality of composite fiber layers around said mandrel wherein the longitudinal axis thereof is oriented at a first angle with respect to the longitudinal axis of said mandrel. The composite tubular member produced does not have any longitudinal seams and is thus considerably stronger and more durable than prior art composite tubes. |
| US08066836B2 |
Prepeg pultrusion
Continuous pultrusion of prepreg material systems is provided. A prepreg material, comprising fibers infiltrated with a partially cured resin, is introduced into a pultrusion die with a barrier layer between surfaces of the prepreg material and facing inner surfaces of the die. The prepreg material and the barrier layers are continuously pulled through the pultrusion die. The barrier layer is removed from each surface of the prepreg material after exiting the die. |
| US08066834B1 |
Burn rate sensitization of solid propellants using a nano-titania additive
Adding nanoparticles as a catalyst to solid propellant fuel to increase and enhance burn rates of the fuel by up to 10 times or more and/or modifying the pressure index. A preferred embodiment uses TiO2 nanoparticles mixed with a solid propellant fuel, where the nanoparticles are approximately 2% or less of total propellant mixture. The high surface to volume ratio of the nanoparticles improve the performance of the solid propellant fuel. |
| US08066830B2 |
Method for producing a shaft for compressors
A method for the production of steels is provided. A heat treatment is carried out, in which the steel is hardened in water twice at different high temperatures, and subsequently subjected to an annealing treatment. It has been shown that the steel 26NiCrMoV14-5 has a high subzero toughness. In one aspect, the steel is usable down to a temperature of at least minus 170° C. |
| US08066829B2 |
Process for manufacturing stamped products, and stamped products prepared from the same
The invention relates to a process for making a hot stamped coated steel sheet product, comprising the steps of pre-coating a steel strip or sheet with aluminium- or aluminium alloy, cutting said pre-coated steel strip or sheet to obtain a pre-coated steel blank, heating the blank in a furnace preheated to a temperature and during a time defined by diagram according to thickness, at a heating rate Vc between 20 and 700° C. comprised between 4 and 12° C./s and at a heating rate Vc′ between 500 and 700° C. comprised between 1.5 and 6° C./s, to obtain a heated blank; then transferring said heated blank to a die, hot stamping the heated blank in the die obtain a hot stamped steel sheet product, cooling at a mean rate Vr between the exit of the heated blank from the furnace, down to 400° C., of at least 30° C./s. |
| US08066828B2 |
Method for efficient heat treatment of steel
A method for heat treatment of steel and a system thereof is provided. First the steel is austenitized at a suitable temperature and then the temperature is rapidly brought down to the austempering temperature. Here the cyclic austempering is carried out between two austempering temperatures by modulating the temperature with controlled heating and cooling and the controlled temperature modulation is obtained by controlling the temperature-time profile in a batch furnace or by controlling the zone temperatures in a continuous furnace. This method of cyclic austempering reduces the austempering time, reduces the energy consumption and emissions, enhances the productivity and reduces the process cost. |
| US08066826B2 |
Rolling-contact shaft with joint claw
A steel-made rolling-contact shaft with a joint claw improved in both the rolling contact fatigue life at the raceway and the static fracture strength (torsional strength) at the claw includes a joint claw at one end, and has a portion of the outer cylindrical surface functioning as a raceway of a needle roller qualified as a rolling element of a needle bearing. The joint claw is subjected to tempering by induction heating. A nitrogen-enriched layer is formed at the surface layer of the rolling-contact shaft with a joint claw. The grain size number of austenite grains in the nitrogen-enriched layer exceeds number 10. The hydrogen content of the rolling-contact shaft with a joint claw is not more than 0.5 ppm. |
| US08066825B2 |
(CoFe)Zr/Nb/Ta/Hf based target material
A (CoFe)Zr/Nb/Ta/Hf based target material is provided which is capable of achieving a high sputtering efficiency and a high sputtering effect by increasing the leakage magnetic flux in the magnetron sputtering, and a method for producing the target material. This target material is made of an Fe—Co based alloy comprising not less than 80 atomic % in total of Fe and Co having an Fe:Co atomic ratio of 80:20 to 0:100, and less than 20 atomic % of one or more selected from the group consisting of Zr, Hf, Nb and Ta. The Fe—Co based alloy comprises a Co—Fe phase being a ferromagnetic phase, and the one or more selected from the group consisting of Zr, Hf, Nb and Ta are incorporated in solid solution form into the Co—Fe phase in a total amount of 0.5 to 2 atomic %. |
| US08066819B2 |
Method of removing organic materials from substrates
Water-free, gaseous sulfur trioxide is used as an agent to remove various organic coatings, films, layers and residues from the surface of a substrate when used in conjunction with certain other physical and chemical treatments applied at the appropriate time during the process. |
| US08066818B2 |
Water-soluble pouch
A detergent multi-compartment pouch having a plurality of water-soluble films forming a plurality of compartments the pouch comprising two side-by-side compartments superposed onto another compartment wherein at least two different compartments contain two different compositions. |
| US08066814B2 |
Crystal-growing furnace having slurry drainage duct structure
A crystal-growing furnace having a slurry drainage duct structure includes a furnace body, a supporting table, a loading frame, a plurality of eaves elements, and a set of eaves gutters. The supporting table includes a table plate and a plurality of supporting posts. The loading frame includes a lower plate and four side plates, where four elongated eaves boards descend from sides of the lower plate. Four eaves gutters, having V-shaped grooves, are connected with one another and disposed beneath the four eaves elements correspondingly. Any high-temperature silicon slurry leaks from a furnace crucible will be guided by the elongated eaves boards into the V-shaped grooves of the eaves gutters to prevent the silicon slurry from flowing along the periphery of the table plate and down to the supporting posts. |
| US08066812B2 |
Durable magnesium oxychloride cement and process therefor
A magnesium oxychloride cement (MOC) composition comprising: caustic calcined magnesia magnesium chloride phosphoric acids or corresponding salts exfoliated vermiculite. |
| US08066809B2 |
Red reactive dyes, their preparation and their use
Reactive dyes of formula wherein R1 and R2 independently of one another are hydrogen or unsubstituted or substituted C1-C4alkyl, D is a radical of a diazo component of the formula X1 and X2 independently of one another are halogen, T is a fiber-reactive radical of the formula (R3)0-2 denotes from 0 to 2 identical or different substituents from the group halogen, C1-C4alkyl, C1-C4alkoxy and sulfo, Z is vinyl or a —CH2—CH2—U radical and U is a group that is removable under alkaline conditions, Q is a —CH(Hal)-CH2-Hal or —C(Hal)=CH2 group, Hal is halogen, n is the number 0, 1 or 2, and m and q are independently of one another the number 0 or 1, are suitable for dyeing cellulosic or amide-group-containing fiber materials. |
| US08066804B2 |
Scrubber
A scrubber for separation of liquid phase and any other constituents from a fluid now that in substance includes a gas. The scrubber is formed as a standing vessel with round cross section, with an outlet for liquid from the bottom and an outlet for gas from the top. The scrubber is distinguished in includes a fluid inlet that either is tangentially oriented relative to the inner wall of the scrubber or equipped with a deflection plate, such that introduced fluid is directed tangentially horizontal or with a small downward slope along the inner wall of the scrubber, into and through a fluid way arranged as a downwards directed spiral within the scrubber, along the inner wall, from a level over or at the inlet to a level at or close to the outlet for liquid, with an opening for gas escape inwards toward the center of the scrubber. The scrubber according to the invention results in very low liquid entrainment. |
| US08066799B2 |
Method of making a crosslinked fiber membrane from a high molecular weight, monoesterified polyimide polymer
The present disclosure relates to a high molecular weight, monoesterified polyimide polymer. Such high molecular weight, monoesterified polyimide polymers are useful in forming crosslinked polymer membranes for the separation of fluid mixtures. According to its broadest aspect, the method of making a crosslinked membrane comprises the following steps: (a) preparing a polyimide polymer comprising carboxylic acid functional groups from a reaction solution comprising monomers and at least one solvent; (b) treating the polyimide polymer with a diol at esterification conditions in the presence of dehydrating conditions to form a monoesterified polyimide polymer; and (c) subjecting the monoesterified fiber to transesterification conditions to form a crosslinked fiber membrane, wherein the dehydrating conditions at least partially remove water produced during step (b). The crosslinked membranes can be used to separate at least one component from a feed stream including more than one component. |
| US08066793B2 |
Bio-processed mineral fertilisers including micro-elements
Dry fertilizers of biologically degraded crushed minerals such as limestone, rock, or rock phosphate together with micro-organisms, including one or more selected supplementary trace elements, are described. Minerals, some sawdust, an inoculum, and nutrients or other protein material, including bound selected micro-elements or trace elements are stored under aerobic conditions for some weeks during thermophilic biological degradation. The resolution fertilizer releases the macro-elements and micro-elements over a long period of time. The microelements are include within a biomass of micro-organism (5-6% carbon in the resulting fertilizer) and are more effective in remedying plan or animal deficiencies than if administered as inorganic salts. Furthermore this fertilizer avoids leaching of mineral including phosphate (phosphorus) and microelements into groundwater, streams, rivers or lakes. |
| US08066788B2 |
Engine generator
An engine generator including an engine, a generator and an air cleaner inside a case is disclosed. A wall section of the case is dented in the internal direction of the case to provide a filter accommodation section with a space for accommodating a filter. The space has an opening that opens toward the exterior of the case. The filter accommodation section has an outside-air intake port. The opening is blocked by an air cleaner cover. |
| US08066784B2 |
Method for the production of membrane/electrode units
The invention relates to a method for production of a membrane/electrode unit, whereby a conducting polymer membrane is compressed with two electrodes until a given compression is achieved. Said method permits an increase in resting voltage of the membrane/electrode unit in use, the amount of damage during production is reduced and a constant thickness within a production run is achieved. |
| US08066782B2 |
Azomethine direct dyes or reduced precursors of azomethine direct dyes obtained from 2-alkylresorcinols, and hair dyeing process using these dyes or precursors
The invention relates to the dyeing of keratin fibres using azomethine direct dyes or precursors of azomethine dyes obtained from 2-alkylresorcinols. The invention relates to a dye composition comprising at least one azomethine direct dye or pre-cursor of an azomethine direct dye, to a process for dyeing keratin fibres, using the said composition, and to their uses in the dyeing of keratin fibres. This composition allows a particularly stable and fast coloration to be obtained. |
| US08066781B2 |
Composition comprising at least one fatty substance and at least one cationic polymer, dyeing or lightening process using it and devices therefor
The present disclosure relates to a composition for dyeing or lightening human keratin fibers, comprising: a cosmetically acceptable medium; at least 25% by weight of at least one fatty substance; at least one cationic polymer; at least one dye chosen from oxidation dyes and direct dyes; at least one basifying agent; and at least one oxidizing agent. The disclosure also relates to a dyeing or lightening process using it. Another subject of the disclosure is multi-compartment devices or kits for obtaining, after mixing together the compositions of the compartments, just before its application, a composition according to the disclosure. |
| US08066780B2 |
Methods for gastric volume control
A gastric balloon includes a scaffold structure, one or more internal inflatable compartments within the scaffold structure, and one or more inflatable bladders formed over the space-filling compartment. The gastric balloon may be deployed transesophageally using a gastroscope and is inflated in situ, preferably using a combination of liquid and gas inflation media. |
| US08066776B2 |
Tibial component
Prosthesis for implantation in the knee having a tibial component for attachment to the tibia. The tibial component has a first, upper surface and a second, lower surface opposite the first surface for attachment to the tibia. The first surface includes a lateral bearing region having a convex form and a medial bearing region having a flat form, arranged such that the respective angles of inclination in sagittal planes of the lateral and medial bearing regions of the component in situ when fitted to the tibia are different. |
| US08066775B2 |
Joint implant
A joint implant, includes a neck and a blade extending along a longitudinal axis and connected to the neck to form a blade plane. A plurality of bores is located in the blade, each of the bores having a central axis, the axes being oriented so that none project at the same angle relative to the blade plane. |
| US08066770B2 |
Sintered coatings for implantable prostheses
The present invention concerns articles having an outer surface that bears at least two layers of metal particles, wherein the at least two layers comprise an outermost layer and an intermediate layer; the outermost layer consisting essentially of aspherical metallic particles having a mean particle size of 50 to 500 microns; and the intermediate layer consisting essentially of substantially spherical metallic particles having a mean particle size of from 50 to 500 microns. In some embodiments, the outer surface has a volume porosity of between about 20% to about 80%. |
| US08066762B2 |
Assembly for manufacturing an implantable polymeric medical device
A polymeric tube is positioned on a polymeric mandrel and then laser cut to form an implantable medical device, such as a stent. The method reduces contamination of the inner surface of the stent, which would be caused if conventional glass or metal mandrels are used, while simultaneously reducing damage to the inner surface of the stent due to the shielding effect of the polymeric mandrel. |
| US08066761B2 |
Stenting method for blood vessels
A method of imposing a shape on an intact blood vessel other than a graft includes inserting a stent in the vessel. The stent includes a supporting portion which internally supports an interior wall of the vessel. The supporting portion includes a hollow tube, the walls of which have openings therein so that the interior wall of the vessel is exposed via the openings to fluid flow along the vessel. A central axis of the hollow tube forms a non-planar three dimensional at least partially helical shape. The hollow tube imposes the three-dimensional at least partially helical shape on the central axis of the vessel, inducing a swirling fluid flow within the stent supported part of the vessel. |
| US08066759B2 |
Resonator for medical device
A resonator device for medical device is provided. The resonator device includes a helical structure and a capacitor structure. The resonator device can be used in conjunction with a medical device, including a stent. |
| US08066757B2 |
Blood flow restoration and thrombus management methods
Systems, methods, and devices for the treatment of acute ischemic stroke that provide immediate blood flow restoration to a vessel occluded by a clot and, after reestablishing blood flow, address the clot itself. Immediate blood flow restoration advantageously can facilitate natural lysis of the clot and also can reduce or obviate the concern for distal embolization due to fragmentation of the clot. Several embodiments of the invention provide for progressive, or modular, treatment based upon the nature of the clot. For example, the progressive treatment can comprise a three-step progressive treatment process that includes immediate restoration of blood flow, in-situ clot management, and/or clot removal depending on the particular circumstances of the treatment. The in-situ clot management can include, for example, lysis and maceration. The progressive, or modular, treatment can be provided by a system or kit of one or more treatment devices. |
| US08066756B2 |
Containment sleeve and deployment device
A deployment device for deploying stents, stent-grafts and other implants into a patient includes a catheter (112) with a containment sheath (116). Held onto the catheter (112) is a stent-graft structure (120). The containment sheath (116) extends over the entirety of the stent graft section (122) so as to constrain it in its entirety on the catheter (112), until the sheath (116) is removed. The containment sheath (116) extends from the distal position (126) of the stent graft section (122) to the tip (114) and then into the central lumen (128) of the catheter (112). It may extend throughout the lumen (128) to the proximal end of the deployment device (10), in other words to the external manipulation section of the delivery device (10). The sheath (116) is withdrawn by pulling towards the external manipulation section of the delivery device. As this is effected, the containment sheath (116) is pulled over the end (114) of the catheter and into the central lumen (128) of the catheter (112). As this occurs the containment sheath (116) is in effect withdrawn into the catheter (112), thereby releasing the stent-graft section (122) gradually. Continued pulling will gradually pull the entirety of the containment sheath (116) into the open end of the catheter (112), thereby releasing the entirety of the stent-graft section (122). |
| US08066755B2 |
System and method of pivoted stent deployment
The invention provides a stent-graft system comprising a graft member and a stent having a connection end interconnected with the graft member and a free end opposed thereto. A belt retaining structure is provided at the stent free end. A belt is releasably retained in the belt retaining structure and is configured to constrain the stent free end independent of the stent connection end. A method of securing at least one end of a stent-graft within a vessel is also provided. |
| US08066748B2 |
Apparatus and method for affixing body structures
An apparatus for affixing a plurality of body structures together in a flexible manner includes a first articulated fastener having substantially rigid proximal and distal portions, longitudinally separated by a first flexible articulating portion. The first articulated fastener has a first thread direction. A second articulated fastener has substantially rigid proximal and distal portions, longitudinally separated by a second flexible articulating portion. The second articulated fastener has a second thread direction opposite the first thread direction. The first and second articulated fasteners are both adapted for insertion into each of the plurality of body structures. A method of affixing a plurality of body structures together in a flexible manner is also provided. |
| US08066747B2 |
Implantation method for a dynamic stabilization and motion preservation spinal implantation system and method
A dynamic stabilization, motion preservation spinal implant system includes an anchor system, a horizontal rod system and a vertical rod system. The systems are modular so that various constructs and configurations can be created and customized to a patient. |
| US08066746B2 |
Variable angle connection assembly
In a preferred embodiment, the present invention provides a connection assembly that can be used to securely connect a spinal implant to a bone anchor. In particular, the present invention preferably provides a variable angle connection assembly that is able to securely connect the spinal implant to the anchors even when there is a variance in the angle and position of the anchors with respect to the spinal implant. Furthermore, in a preferred embodiment, the present invention provides a connection assembly that will not inadvertently lock the components of the connection assembly preventing the relative movement of the components. |
| US08066736B2 |
Dynamic bioabsorbable fastener for use in wound closure
A fastener for insertion into pierced openings of a tissue wound has a body formed of a generally bioabsorbable polymer defining an initial capture area. The body includes a pair of arms, each with an inwardly projecting cleat operably joined at an elbow portion defining an internal elbow angle. The arms are operably joined to a backspan at a shoulder portion defining an internal shoulder angle. A durable tissue retention zone is defined between the cleat and the arm. The elbow portion and the internal elbow angle define an insertion width greater than a width of the pierced openings resulting in the pierced openings stretching over the cleat and being elastically retained within the durable tissue retention zone. The fastener captures wound tissue in the initial capture area and then dynamically reforms in response to lateral stresses without a fracture failure of the fastener until a minimum degradation period. |
| US08066735B2 |
Scar-free wound closer with opposing knife guides
A zipper-type wound closer attachable to the skin around a skin opening and zipped closed to pull the skin opening closed. The wound closer includes two elongated connecting strips whose feet are pre-coated with adhesive and attached to the skin around the skin opening. The edges of the wound are trimmed flush with the interior sides of connecting strips, and the strips are then zipped together by moving a slider along the connecting strips to join the strips together like a familiar zipper. The wound zipper forms a continuous, toothless seam to prevent seepage of fluid through the seam. By holding the freshly trimmed edges of the skin opening together immobile in a clean, firm, closely aligned connection, the wound closer recreates the conditions under which scar-free healing of the skin can occur naturally; useful for repairing wounds and removing existing scars. |
| US08066730B2 |
Medical dilator system or dilator device
A medical dilating system and method are provided that include a dilator device having an elongated shape with an exterior surface, a first end and a second end. The first end of the dilator device includes a tapered tip configured to penetrate and provide an opening in the tissue of a patient, and a plurality of sleeves cooperatively configured to widen the opening in the tissue. The dilator device includes an interior wall that generally defines an open interior volume extending from an opening of the second end of the dilator device to one or more openings in the tapered tip at the first end of the dilator device. Each of the plurality of sleeves has an elongated shape with an exterior surface, a first end, a second end, and an interior wall that generally defines an open interior volume substantially extending from an opening of the first end of the respective sleeve to the second end of the respective sleeve. The plurality of sleeves include at least a first sleeve operable to allow the internal wall of the first sleeve to be substantially positioned around the exterior surface of the dilator device, and a second sleeve operable to allow the internal wall of the second sleeve to be substantially positioned around the exterior surface of the first sleeve. |
| US08066729B2 |
Surgical obturator
An obturator has an elongated shaft with a first shaft portion and a second shaft portion within an obturator housing. The distal end of the first shaft portion creates a first shield and the distal end of the second shaft portion creates a second shield. A blade having a piercing tip and cutting edges is interposed between the first shield and the second shield. In use, once the piercing tip passes the body wall, the first shield moves to cover the piercing tip and protect internal organs from accidental injury while the cutting edges continue to cut the body wall. Once the second shield passes through the body wall, the second shield moves to cover the cutting edges. |
| US08066723B2 |
Connector, applicator and method for mechanically connecting hollow structures, in particular small blood vessels, as well as auxiliary devices
The invention relates to a connector (1), applicator and method for mechanically connecting hollow structures, in particular small blood vessels, in order to make an anastomosis. The connector incorporates various features to create a reliable engagement with the vessel walls to make a good connection thereof. The applicator may comprise knife members to make an arteriotomy and punch a hole in one of the vessel walls, comprises an expansion portion to cause a large expansion with a minimum profile, and comprises anvil members to reliably bring staple-like elements (5) of the connector to the joining position. The invention also includes auxiliary devices such as a punch and deforming instrument. |
| US08066716B2 |
Instruments and techniques for controlled removal of epidermal layers
An instrument and technique for the removal of epidermal layers in a controlled manner utilizing a hand-held instrument with a working end that (i) a vacuum aspiration system, (ii) a source for delivery of a sterile fluids or pharmacological agents to the skin; and (iii) a skin interface surface in the working end that has specially shape structure for abrading surface layers of the patient's epidermis as the working end is moved over the patient's skin while at the same time causing rapid penetration of the fluids into the skin for therapeutic purposes. Movement of the working end across the skin causes abrasion of the surface layers in a path over the patient's skin. The method of the invention may be used in a periodic treatment for the removal of superficial skin layers that enhances the synthesis of dermal collagen aggregates by inducing the body's natural wound healing response. The method of the invention creates more normal dermal architectures in skin with limited depths of skin removal by the series of superficial treatments that may be comparable to the extent of neocollagenesis caused by a deep skin removal treatment (e.g., CO2 laser skin removal). |
| US08066715B2 |
Magnetic stent removal
A medical device and method for its use in the digestive system of a mammalian patient is provided. The medical device includes a stent and a retrieval device. The stent has a magnetic element connected to an end of the stent. The retrieval device includes a magnetic member, and the retrieval device is sized to be ingested by the patient. The magnetic member is capable of being magnetically coupled to the magnetic element of the stent for removal of the stent through the natural forces of the digestive system. |
| US08066712B2 |
Systems for delivering bone fill material
The disclosure relates in certain embodiments to medical devices, systems and methods for use in osteoplasty procedures, such as vertebral compression fractures. One system for delivering a bone fill material to a bone includes an elongated introducer configured for insertion into a bone and having a channel sized to allow a flow of bone fill material therethrough. The introducer has at least one outlet opening in communication with the channel for delivering the bone fill material into the bone. A thermal energy emitter is coupled to the introducer and configured to apply thermal energy to the bone fill material flowing through the introducer. A sensor and a computer controller can be used to measure data about the bone fill material and to control certain aspects of the flow of bone fill material. A hydraulic pressure source may also be operatively coupled to the introducer and configured to apply a force on the bone fill material to provide a pressurized flow of bone fill material through the introducer. In certain embodiments, the system for use in osteoplasty procedures can include a cooling system that can be used to cool the bone fill material. |
| US08066707B2 |
Method for preparing a space in bone to receive an insert
A method is disclosed for preparing a space in bone of a human body to receive an insert at least in part therein. The method is performed with a device having a mid-longitudinal axis and a rotatable abrading element having an abrading surface. The method includes the steps of: activating the device to cause the abrading surface to move; contacting the abrading surface of the abrading element against the bone to remove bone therefrom to form a surface on the bone to create the space; rotating the abrading element about an axis different from the mid-longitudinal axis of the device; removing the abrading surface from the space; and positioning an insert into the space created in the bone. |
| US08066701B2 |
Energy based devices and methods for treatment of patent foramen ovale
Methods and apparatus for treatment of patent foramen ovale (PFO) provide for applying energy to tissues adjacent the PFO with a catheter device to substantially close the PFO acutely. Apparatus generally includes a catheter device having at least one energy transmission member at or near its distal end configured to apply energy to PFO tissues to acutely, substantially close the PFO. Applied energy may be monopolar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating or the like. Some embodiments of a catheter device further include one or more tissue apposition members near the distal end for helping bring PFO tissues together, such as a PFO covering member, a vacuum applying member and/or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions. |
| US08066700B2 |
Cartilage treatment probe
An electrosurgical instrument includes a shaft, a flexible portion, and a head coupled to the shaft through the flexible portion and pivotably coupled to the flexible portion. The head includes a non-conductive surface and an electrically conductive surface. The flexible portion is configured to bias the non-conductive surface and the electrically conductive surface towards a tissue surface, such as cartilage. The non-conductive surface may include a material having a thermal conductivity less than or equal to about 30 W/m*K and/or a volume resistivity greater than or equal to about 1×1014 ohm*cm. The non-conductive surface may include a ceramic such as Macor® ceramic, ZTA ceramic, and/or 99.5% alumina ceramic. |
| US08066690B2 |
Method for delivering medication into an arterial wall for prevention of restenosis
A method for preventing a restenosis within a vessel wall requires a medicament be delivered at predetermined locations into the vessel wall and allowed to subsequently disperse in a predetermined pattern. To deliver the medicament, a catheter with an expanding member is advanced into the vasculature of a patient until the expanding member is located as desired. The expanding member is then expanded to force dispensers into the vessel wall to the proper depth. A medicament is then pumped through the dispensers to create a plurality of equally spaced, localized medicinal deliveries which subsequently disperse to medicate an annulus shaped volume within the vessel wall. |
| US08066684B2 |
Disposable pants
This invention provides disposable pants usable as both pants and a diaper, which ensure excellent stretchability to facilitate raising/lowering when putting them on, and the like. The disposable pants have functions of both pants and a diaper, and a left front abdominal part and a right front abdominal part can be expanded to the left and right by breaking left and right breaking parts. The left front abdominal part and right front abdominal part are provided with adhesive pieces attached/detached to/from an adhesive part of a central front abdominal part. The ratio between a lateral dimension of the front abdominal section in a stretched state and a lateral dimension between positions to which the left and right adhesive pieces are bonded, respectively, is set to fall within a range of 0.05≦X2/X1≦0.55, which ensures stretchability of the front abdominal section. |
| US08066676B2 |
Catheter components formed of polymer with particles or fibers
A guidewire lumen for a catheter includes a tubular member. At least a portion of the tubular member is formed of a compound comprising a polymer and particles or fibers. The particles or fibers can reduce a friction coefficient of the portion of the tubular member while having minimal to no adverse effects with respect to bondability, flexibility, and processability. |
| US08066673B2 |
Cannula stabilization seal
A stabilization seal is used with existing cannulas for forming a gas-tight seal with tissue in a body wall. The stabilization seal includes a cylindrical inflatable elongate tube having a graduated wall-thickness that is thicker in a central region and thinner in a distal-end region. The tube includes a sealing cuff, having an inflation port, for sealing around a cannula. Application of inflation pressure greatly expands the distal-end region while the central region expands slightly. Another embodiment of a stabilization seal includes an inflatable thread that is used with a cannula having a helical channel on its outer surface. An inflatable tube is wound into the channel. A distal end of the tube includes a gas-tight seal and a proximal end of the tube includes an inflation port. In the uninflated condition the nested tube is flush with the channel. Inflating the tube enlarges the cannula assembly. |
| US08066671B2 |
Automated dialysis system including a piston and stepper motor
A peritoneal dialysis system includes a hardware unit including a piston having a contact surface and a stepper motor configured to move the piston; and a disposable unit received by the hardware unit, the disposable unit including a moveable membrane operable with the contact surface of the piston, the piston moveable towards and away from the disposable unit, wherein (i) the piston and the membrane are positioned relative to each other and (ii) the hardware unit is configured to apply a negative pressure to the moveable membrane of the disposable unit so that the negative pressure causes the moveable membrane to contact and conform to a shape of the contact surface and to follow the piston as the piston is moved away from the disposable unit by the stepper motor, and wherein the shape-contacted membrane moves with the piston as the piston is moved into the disposable unit by the stepper motor. |
| US08066669B2 |
Vascular access device housing venting
A Luer access device may include a housing, a septum, and a gas permeable vent in communication with at least a portion of the housing for venting gas from an extravascular system. A method of venting a medical device may include providing a gas permeable vent within a Luer access device as part of an extravascular system and venting gas from the extravascular system through the gas permeable vent of the Luer access device. |
| US08066665B2 |
Device and method employing shape memory alloy
A system for the metering and delivery of small discrete volumes of liquid is comprised of a small or minimal number of inexpensive components. One such component is a movable member, such as a miniature precision reciprocating displacement pump head, which is driven by an actuator that comprises a shape memory alloy material. The operating mechanism of the system is of little or minimal complexity. The system facilitates the precise metering and delivery of the small discrete volumes of liquid. Potential applications for the system include subcutaneous, long-term, automated drug delivery, for example, the delivery of insulin to a person with diabetes. In such an application, the small, simple and inexpensive nature of the invention would allow for its use as both a portable and a disposable system. |
| US08066664B2 |
Tri-directional articulating catheter
A catheter capable of articulating in two and three directions is provided. Articulation at the distal tip of the catheter is facilitated by applying selective tension on a steering wire disposed in a lumen that resides peripheral to a central working lumen. Tension on the steering wire through the peripheral lumen causes the catheter tip to bend while the central working lumen resists compression. |
| US08066659B2 |
Apparatus and method for treating and dispensing a material into tissue
An apparatus for administering a therapeutic is provided. In various embodiments, the apparatus includes a syringe having a barrel and a plunger and having a material treatment module associated therewith. The material treatment module may be an ozone generator that is initiated such that material containing ozone accumulates within the barrel. The material can then be delivered from the barrel into a target site via a needle, thereby delivering therapeutic effects to that target site. |
| US08066658B2 |
Method and composition for removing uremic toxins in dialysis processes
Methods and devices for providing dialysis treatment are provided. The device includes a resin bed including zirconium phosphate, zirconium oxide, and urease. |
| US08066657B2 |
Abdominal binder with improved drainage bulb holding system
An improved abdominal binder is provided. The abdominal binder can include at least one external securing mechanism for holding a drainage bulb. In one embodiment, the securing mechanism can include one or more strips of hook or loop type material. In another embodiment, an improved abdominal binder that can support multiple drainage bulbs externally of the abdominal binder is provided. The improved abdominal binder can further include one or more openings to receive a drainage tube of a bulb held external to the abdominal binder. |
| US08066655B2 |
Protective glove
A protective glove is disclosed that provides a user with protection against radial luxation or subluxation of the user's thumb during activities in which the user's thumb can be subjected to forces that may dislocate the thumb in relation to the hand. In one preferred embodiment, the protective glove is a ski glove that includes a bracing element to prevent injurious movement of a snow skier's thumb when a ski pole used by the skier forcefully reacts to movement of the ski pole as the pole is inserted or dragged within the snow upon which the skier is skiing. In other embodiments, the present invention may also be utilized by as user participating in activities such a skiing, rodeos, football, hockey, polo, baseball, and lacrosse. |
| US08066652B2 |
Massage device with a hoist transmission mechanism
The present invention relates to a massage device. In one embodiment, the massage device includes a massage assembly and a transmission assembly for driving the massage assembly to provide massage effects. The massage assembly includes a pair of massage members. Each massage member has a driving member having a pair of eccentric gears, a massage bracket engaged with the driving member and a plurality of massage heads attached to the massage bracket. The transmission assembly includes a hoist transmission mechanism. |
| US08066649B2 |
Integrated sensor for analyzing biological samples
An integrated lancet and testing striplet for measuring a body analyte level in a health care regimen includes a skin piercing member and an analyte sensor coupled together. |
| US08066648B1 |
Fluid connector and biopsy system including same
A fluid connector is provided for a biopsy system that includes a vacuum assisted biopsy device, a first fluid source and a second fluid source. In an embodiment, the fluid connector includes a body member having a first input port, a second input port and an output port. The first input port includes a first check valve in fluid communication with the first fluid source, the second input port includes a second check valve in fluid communication with the second fluid source and the output port is provided in communication with the vacuum assisted biopsy device. A biopsy system including a fluid connector of the present invention is also provided. |
| US08066647B2 |
Method for detecting and discriminating breathing patterns from respiratory signals
A signal representative of a patient's respiration is split into equal length epochs. A primary feature is extracted from each epoch that acts as a compressed representation of the signal events. Statistics are applied to the primary feature to produce one or more secondary features that represent the entire epoch. Each secondary feature is grouped with one or more other features that are extracted from the entire epoch rather than selected epoch events. This grouping is the epoch pattern. The pattern is manipulated with suitable classifier algorithm to produce a probability for each class within the algorithm, that the signal may be representative of a disease state (Cheyne-Stokes, OSA etc). The epoch is assigned to the class with the highest probability. Also defined are methods of detecting Cheyne-Stokes breathing by analyzing a signal to detect one or regions of hyperpnoea and if the length of a hyperpnoea exceeds a parameter, Cheyne-Stokes is present. |
| US08066645B2 |
Blood pressure bleed valve assembly
A bleed flow valve assembly for venting air from a blood pressure cuff at relatively constant pressure decrease rate irrespective of cuff size includes a multiple chamber bleed valve and a multiple position control valve operatively associated therewith. A first end chamber is connected in pneumatic communication with the cuff and pneumatically sealed from a second central chamber by a first flexible diaphragm. A third end chamber is separated from the central chamber by a second flexible diaphragm. A variable flow area opening through the second diaphragm provides a flow path for controllably venting air from the second chamber to ambient pressure when the control valve is selectively positioned to connect the third chamber in pneumatic communication with ambient pressure. Air is vented from the cuff through the first chamber in regulated response to the pressure differential between the first chamber and the second chamber acting upon the first flexible diaphragm. |
| US08066644B2 |
System, method and device for positioning a target located within soft tissue in a path of an instrument
A system, method and device for positioning a target located within soft tissue in a path of an instrument inserted into the soft tissue includes: a manipulation system including a plurality of force applicators positioned around the soft tissue containing the target; an image acquisition system including an imaging probe for obtaining data for generating an image of the soft tissue containing the target; a detection means for detecting deflection of the target using the data from the imaging probe; and a control means for actuating the plurality of force applicators to apply forces on the soft tissue in response to a detected deflection of the target to move the target back in line with the path of the instrument. In an exemplary embodiment, the soft tissue is a breast, the imaging probe is an ultrasound imaging probe, and the instrument is a biopsy needle. |
| US08066642B1 |
Systems and methods for ultrasound beam forming data control
Disclosed are systems and methods which efficiently control storage of and/or access to data which includes repetitive data or data which is used by different modes, processes, etcetera. Embodiments provide control for storage of and/or access to large amounts of data used in ultrasound system beam forming for image generation using a hierarchy of sequencers for controlling storage of and/or access to data. A frame sequencer may provide control at a frame level while an address sequencer is implemented to provide control at a data access level. |
| US08066641B2 |
Method and system for treating photoaged tissue
A method and system for ultrasound treatment of photoaged tissue are provided. An exemplary method and system are configured for first, ultrasound imaging of the region of interest for localization of the treatment area, second, delivery of ultrasound energy at a depth and pattern to achieve the desired therapeutic effects, and third to monitor the treatment area during and after therapy to assess the results and/or provide feedback. The exemplary treatment method and system can be configured for producing arrays of sub-millimeter and larger zones of thermal ablation to treat the epidermal, superficial dermal, mid-dermal and deep dermal components of photoaged tissue. |
| US08066635B2 |
Speculum
A speculum having a generally U-shaped frame with a pair of arms, each arm having a free end, a pair of cups, each cup coupled with the free end of one of the arms, and a pair of surfaces, each surface coupled with one of the cups and having a portion extending upward at an angle from the frame. |
| US08066634B2 |
Digital otoscope
A digital otoscope for capturing live and still digital images of body tissue and having associated optical characteristics that improve the quality of visual information gathered for medical inspection of both human and veterinary subjects. The digital otoscope includes a tip element having dimensions that are small enough to fit into a small body cavity, such as an ear canal. The tip element and the otoscope enclose an assembly of optical components yielding optical characteristics that provide a substantially wide field of view and a substantially wide range of optimal focus from which to form visual information within a small and confined body cavity. |
| US08066630B2 |
Holding and resting device for medical instruments having essentially cylindrical instrumental bodies
The invention relates to a holding and resting device for medical instruments having essentially cylindrical instrument bodies, in particular endoscopic instruments, with a base body that can be secured for instance to an operating table and an instrument input to be inserted into the base body and in which the instrument body can be secured by clamping. To create a holding and resting device for medical instruments having essentially cylindrical instrument bodies, which is of simple construction and can be activated quickly and safely, it is proposed with the invention that the instrument input includes a ring-shaped tension casing with at least two holder arms as well as a tension nut that works together with the tension casing. |
| US08066628B1 |
Intra-aortic balloon pump and driver
Devices and methods are disclosed for implanting, positioning, removing, replacing and operating intra-aortic balloon pumps. |
| US08066626B2 |
Conductive rubber member
The conductive rubber member of the invention has a conductive elastic layer to which conductivity has been imparted and which serves as an outermost layer, and a surface-treated layer formed through impregnating a surface of the conductive elastic layer with a surface-treatment liquid containing at least an isocyanate component and an organic solvent, wherein the surface-treated layer is formed of an upper portion on the outermost side, and a lower portion beneath the upper portion, the upper portion has a density of the isocyanate component which is greater on the inner side than on the surface side within the upper portion, and the lower portion has a density of the isocyanate component that gradually decreases inwardly. |
| US08066624B1 |
Ergonomic exercise posture chair and method of using same
An exercise chair includes a seat; a base having one or more base supports, the one or more base supports configured to contact a support surface; a seat support supporting the seat, pivotally connected to the base, and biased upward, the seat support including a fulcrum, and wherein downward pressure on the seat by a sitting user causes the fulcrum of the seat support to contact that support surface in addition to one or more of the one or more base supports, forcing the user to maintain a balanced posture on the seat in order to maintain the seat support in a vertical orientation. |
| US08066622B2 |
Complex bench press
Disclosed is a complex bench press which can be switched into a flat bench press, a decline bench press, or an incline bench press to achieve improved space utilization in a narrow space, and which enables users to switch the bench press into the bench press for a specific function in a significantly simple and quick manner to achieve improved convenience of use, and which enables users to always assume a posture appropriate for exercising even when the bench press is switched into the bench press for a specific function, to thereby protect users from injury during exercise. |
| US08066619B2 |
Clutch control system
A clutch control system is interposed between an engine and a piece of driven equipment. The clutch control system includes a clutch assembly with input and output speed sensors for providing signals corresponding to the shaft rotational speeds of the engine and the driven equipment, respectively. A pressure sensor is connected to the clutch assembly and provides an output signal corresponding to clutch pressure. A temperature sensor is also associated with the clutch assembly and provides a temperature signal corresponding to the operating temperature of the clutch assembly. Transducers of various types are also employed to sense operating conditions such as shock loads or the like. Also included is a machine control system connected to the driven equipment and an engine control module connected to the engine, both of which are interconnected through an SAE J1939 CAN to the clutch control unit. These signals are passed to a clutch control unit that employs the signals to assess the operating conditions of the system and accordingly adjust the clutch pressure through a pressure control valve. A vast array of operating data is available from the system and is employed by the clutch control unit to ensure optimum operation, by tailoring the clutch pressure to the engine and driven equipment, thus minimizing clutch slippage and avoiding or instantaneously correcting shock load situations. |
| US08066617B2 |
Method for controlling shifts in an automated step-down transmission
A method of controlling an automated step-down transmission, arranged in a drivetrain between an engine and a drive axle, which includes a multi-stage main transmission and a range group. The main transmission has an intermediate transmission style with a countershaft having a transmission brake and an input shaft connected, via a clutch, to the engine. The main transmission shifts, without being synchronized, and the range group shifts, after synchronization, such that the engaged gear ratio of the main transmission remains engaged during a range shift operation. The range shift is accomplished by firstly reducing drive engine torque; secondly, disengaging the existing gear ratio of the range group; thirdly, remotely synchronizing the target gear ratio in the range group; fourthly, engaging the target gear ratio in the range group; and fifthly, increasing the drive engine torque. |
| US08066616B2 |
Control apparatus for vehicular automatic transmission
A control apparatus for a vehicular automatic transmission, which permits effective reduction of deterioration of vehicle drivability upon operation of a brake operating member, and which is configured to increase a sweeping rate in a sweep control of the torque capacity of a coupling element of an automatic transmission portion 20 to be engaged to perform a shifting action when a regenerative braking command is generated according to the operation of the brake operating member during an inertia phase of the shifting action, so that the coupling element is rapidly engaged for the purpose of generating an engine braking force when the regenerative braking command is generated according to the operation of the brake operating member during the inertia phase of the shifting action. Accordingly, the braking force generated during the shifting action is equal to the braking force generated in the normal state (in the absence of the shifting action). |
| US08066615B2 |
Method and apparatus to detect a mode-gear mismatch during operation of an electro-mechanical transmission
A method for operating the powertrain includes monitoring operator inputs, monitoring a transmission output, and terminating an engine operating mode when a time-rate change in the transmission output exceeds a threshold absent a change in the monitored operator inputs. |
| US08066614B2 |
Continuously variable transmission
A variable speed transmission having a plurality of tilting balls and opposing input and output discs is illustrated and described that provides an infinite number of speed combinations over its transmission ratio range. The use of a planetary gear set allows minimum speeds to be in reverse and the unique geometry of the transmission allows all of the power paths to be coaxial, thereby reducing overall size and complexity of the transmission in comparison to transmissions achieving similar transmission ratio ranges. |
| US08066611B2 |
Electrical tool with a multi-stage gear transmission
An electrical tool includes a multi-stage gear transmission (10) located in the gear transmission housing (6) and having at least two axially displaceable indexing gear (42a, 42b), a shifting device (12) for shifting the gear transmission from one stage to another stage and having a shifting slide (14) linearly displaceable between different shifting positions, and at least two connection elements (32) for connecting the shifting slide (14) with respective indexing gears (42a, 42b), with the shifting slide (14) having a tracing profile (20) having two control tracks (22, 24), and the connection elements each having a first and second tracing sections (30a, 30b) to which the tracing profile (20) applies a shifting force in stages and which are arranged on opposite sides of a pivot axis (SA) of a respective connection element (32). |
| US08066610B2 |
Multi-speed transmission
A transmission is provided having an input member, an output member, four planetary gear sets, a plurality of coupling members and a plurality of torque transmitting devices. Each of the planetary gear sets includes first, second and third members. The torque transmitting devices may include clutches and at least one brake. |
| US08066609B2 |
Electric variable transmission for hybrid electric vehicles with three forward modes, one reverse mode, and five fixed gears
The present disclosure provides a power split transmission with three forward Electric Variable Transmission (EVT) modes, one reverse EVT mode, and five fixed gears for use in hybrid electrical vehicles (HEV). The present disclosure utilizes two electric motors (“E-motors”), an engine, three planetary gear sets, three selectively engageable clutches, and two selectively engageable brakes. The clutches and brakes are engaged in different combinations to engage the different gears and EVT modes. In the five fixed gears, power is transmitted only on the mechanical path for the highest transmission efficiency. In the EVT modes, a part of the power is transmitted electrically. Additionally, the present disclosure includes a front E-motor designed allowing scalable E-motors and a modular transmission design and a center E-motor design. |
| US08066607B2 |
Locking differential having a split-center driver
A locking differential includes a housing with an interior chamber in which a two-piece split-center driver is located. The split-center driver is positioned on opposite sides of a cross-pin assembly. A pair of axially spaced output shafts extend from the interior chamber and are coupled to a pair of side gears. The split-center driver gear and a centered cam member are arranged co-axially about the adjacent ends of the output shafts, and annular clutch members are operable to disconnect an overrunning output shaft. |
| US08066604B2 |
Articulated chain for drive transmission in bicycles
The chain comprises a plurality of external links (2), each defined by a pair of parallel external plates (4, 5) and by two rotation pivots (6) interpositioned between the two external plates (4, 5). The chain also comprises a plurality of internal links (3), each defined by a pair of parallel internal plates (7, 8) and by two bushes (9) interpositioned between the plates and each internal link (3). Each of the rotation pivots (6) is inserted coaxially in a bush (9) and so defines an alternated succession of external links (2) and internal links (3) and defines with the bush (9) a spherical coupling surface. The chain also comprises anti-rotation elements (12) for reducing a possibility of rotation with respect to an alignment direction of each pair of adjacent links (2, 3). |
| US08066597B2 |
Electrically operated derailleur with force overload protection
A derailleur comprises a base member, a movable member; a linkage mechanism including a link member coupled to the base member and to the movable member so that the movable member moves relative to the base member, a motor including a drive member, and a driven member driven by the drive member. The driven member is coupled to the link member so that the link member moves relative to the base member to move the movable member relative to the base member. A clutch is disposed in a power transmission path between the motor and the link member. |
| US08066594B2 |
Baseball bat
Baseball bats described herein may have handle, throat and/or barrel portions that include non-circular cross-sections. |
| US08066591B2 |
Portable retractable surface protection device
An example portable, retractable surface protection device. The example device includes a rotatable support bar, a first support base positioned to a first end of the support bar, a second support base positioned to a second end of the support bar, and a surface cover. A plurality of wheels are positioned to the second support base such that the device is wheelable. The device additionally includes a handle connected to the support bar for wrapping and unwrapping the surface cover onto the support bar. A plurality of removable weights positioned in the surface cover at least partially restrict movement of the surface cover when in a fully or a partially deployed position. |
| US08066587B2 |
Putter head
A putter head includes substantially parallel plural grooves formed on a face thereof, wherein a ratio W/S of a groove width W (mm) and a space width S (mm) between the grooves is from 0.5 to 2.0. |
| US08066585B2 |
Golf club grip
A pre-molded or moldable shaft grip includes a pre-configured or moldable section disposed within a substantially circular outer grip layer. A pre-configured or moldable section substantially conforms to a player's grip, facilitating consistent finger placement. The pre-configured section may comprise the shaft, a separate section, or multiple sections of varying durometer. The moldable section may include a layer of moldable material, or a cavity disposed between the outer grip layer and the shaft containing a moldable substance. Overall grip durometer can be adjusted by varying the pressure within the cavity. |
| US08066584B2 |
Golf club head having a bridge member and a weight positioning system
A golf club head is disclosed that includes a weight integral to a bridge member extending across a cavity back golf club head. The weight modifies a position of a center of gravity of the golf club head. The weight is independently movable in multiple directions to further vary the center of gravity of a golf club head. |
| US08066581B2 |
Putter head
Embodiments of a putter-type golf club head with an increased moment of inertia about the X axis (MOIxx) and an increased moment of inertia about the Z axis (MOIzz) are disclosed. Generally, the MOIzz is increased by designing the putter such that the center of gravity (CG) of the putter head is located at or behind the geometric center of the putter head. Additionally, the mass of the putter head is concentrated at the outer edges of the putter head. To accomplish this, the ratio of the width of the front of the putter head to the width of the rear of the putter head is no greater than 0.55:1. The MOIxx is further increased by locating the CG relatively close to the bottom of the putter head. |
| US08066579B2 |
Pin setter
A pin setter applied to a bowling game machine in which a player rolling a ball toward a plurality of pins arranged in a standing manner on a lane thereby to knock down the plurality of pins. The pin setter that arranges the pins at predetermined positions includes a pin lifter that lifts the pin in a standing state up to the lane, a pin guide that keeps the pin lifted on the lane from falling down, and an evacuation mechanism that evacuates the pin guide from the lane. |
| US08066575B2 |
Constant velocity universal joint and inner member of the same
Automatic installation of a circlip is facilitated even when an axial length (inner race width) of a protrusion of an inner race is reduced. An inner race is installed in a constant velocity universal joint for transmitting torque while allowing angular displacement between itself and an outer race, with a shaft being inserted in a shaft hole formed in an inner bore to be spline-fitted thereto so as to be prevented from coming off by virtue of the circlip. A two-step chamfer having different chamfer angles is provided at a shaft insertion side end portion of the shaft hole. The two-step chamfer includes a first chamfer section situated on a shaft hole opening side and a second chamfer section provided on the side opposite to the shaft hole opening so as to be continuous with the first chamfer section. The chamfer angle α of the first chamfer section is set larger than the chamfer angle β of the second chamfer section. |
| US08066574B2 |
Damper mechanism
A damper mechanism 4 has a clutch plate 21 and a retaining plate 22 disposed aligned in the axial direction, a hub flange 6 disposed relatively rotatably in the axial direction between the plates 21 and 22, and a second coil spring 8 for elastically linking the plates 21 and 22 to the hub flange 6 in the rotational direction. The plates 21 and 22 have a pair of first main body components 28, and a plurality of linking components 31 that are disposed in the rotational direction between first protrusions 49 and second protrusions 57 and that link the pair of first main body components 28. The plurality of linking components 31 is disposed such that adjacent pitches are different. |
| US08066573B2 |
Tubular member having multiple sized splines
A driveshaft assembly includes a tubular slip member having a first spline member having a plurality of splines formed thereon having a first tolerance and a second spline member having a plurality of spline sections. The plurality of spline sections includes a plurality of splines formed thereon having a second tolerance. The second spline member cooperates with the first spline member. A zone is disposed on the second spline member and has a first profile. The zone is disposed adjacent to at least one of the plurality of spline sections of the second spline member, and the first profile defines a clearance relative to the first spline member. |
| US08066571B2 |
System and method for enabling characters to be manifested within a plurality of different virtual spaces
A system and method for providing virtual spaces, where a character associated with a user can be manifested within instances of a plurality of the different virtual spaces. Since a single character can be manifested within instances of different virtual spaces, the character can be transferred by the corresponding user between instances of different virtual spaces and controlled by the user to interact with the different virtual spaces. When the user transfers the character between instances of different virtual spaces (and/or different types of virtual spaces), various aspects of the character may persist between the different virtual spaces (and/or the different types of virtual spaces). This may provide an enhanced continuity to the character between the different virtual spaces. |
| US08066566B2 |
Reconfigurable gaming machine
A gaming machine has at least one video screen, but preferably three. One screen displays a primary game and the other two screens preferably display pay tables, a secondary game, or artwork related to the primary and/or secondary game. The content of the video screens is reconfigurable. The content may be downloaded over a network connecting a plurality of gaming machines to a central computer or the content of several different games may be stored locally within the gaming machine. |
| US08066565B2 |
System, method, and apparatus for the electronic operation, management, sponsorship, advertising, promotion, marketing, and regulation of games of chance on a network
The present invention is directed to a computer network system that allows a user to register for games of chances throughout the country and in accordance with national, state and local laws and ordinances. This system analyses the geographical location and residency information of a user in relation to the geographical access and participation areas permitted, excluded, and restricted for a game of chance as governed by jurisdictional laws, statutes, rules, and regulations. If the user is not located within a permitted area or falls within an excluded or restricted area, the user will not be allowed to access or participate in the game of chance. The ability of the system to limit participation by geographical location is based on user input, data, and variable analysis, and the comparison between the areas where games of chance are permitted, excluded, restricted, and user location and residency, filters data to determine user accessibility to a game of chance, listings, and advertising. The methods and apparatus of this system have applications on the Internet for raffles as well as other conventional games of chance. |
| US08066561B1 |
Methods for playing competitive wagering games
A system, method, and computer readable storage to provide a wagering game that awards bettors who correctly predict which of several parties in competition will be the last to successfully meet the requirements of a predetermined sequence of outcomes. Bettors can also wager on the length of the sequence achieved. |
| US08066556B2 |
Method and system for scalding slaughtered poultry
A method and apparatus (10) for scalding and plucking slaughtered poultry, by way of example chickens, hens, turkeys, ducks or geese, where the poultry is transported via a sluice device through a scalding tunnel (10) are slaughtering, preferably suspended at the feet, where the poultry in the scalding runnel is conveyed successively between rows of nozzles (36) that are adapted to apply scalding agent to the poultry, where a plurality of different scalding agents are applied, where in a first scalding zone hot water is used as scalding agent, where in succeeding scalding zones scalding agents with mutually differing temperatures are applied, where in the said succeeding scalding zones warm humid air is used as scalding agent which is at least blown onto specific sub areas of the poultry. In a simple way optimal plucking may occur subsequently without the poultry subjected to unnecessary heat action, and so that a considerable reduction of the required energy consumption is simultaneously attained. |
| US08066554B2 |
Dust box and electric tool with the dust box
A dust box includes: an attachment portion configured to be attached to a dust-discharging nozzle extending from a housing of an electric tool; and a dust-collecting portion connected to the attachment portion and configured to store dust particles to be discharged from the nozzle. The dust-collecting portion mainly consists of a box which is made of synthetic resin and configured to be detachably connected to the attachment portion, and a paper bag received in the box and configured to store the dust particles to be discharged from the nozzle. |
| US08066552B2 |
Multi-layer polishing pad for low-pressure polishing
A polishing pad has a polishing layer and a backing layer secured to the polishing layer. The polishing layer has a polishing surface, a first thickness, a first compressibility, and a hardness between about 40 to 80 Shore D. The backing layer has a second thickness and has a second compressibility greater than the first compressibility. The first thickness, first compressibility, second thickness and second compressibility are such that the polishing surface deflects more than the thickness non-uniformity of the polishing layer under an applied pressure of 1.5 psi or less. |
| US08066550B2 |
Wafer polishing method and apparatus
A wafer polishing method, in which the outer circumferential edge of a polishing member is first cut by a cutting tool fixed to a table base, thereby forming the polishing member into a completely round shape and also positioning the polishing member in a Y direction at a Y-directional reference position of the table base. Thereafter, a polishing unit is once lifted in the condition where the table base remains still at the reference position. Thereafter, the table base is horizontally moved toward a column in the Y direction to thereby position the polishing member in the Y direction so that only a peripheral portion of the wafer is polished by the polishing member. At this time, the horizontal travel of the table base is preliminarily obtained from the Y-directional positional relation between the cutting tool and the wafer held on a chuck table and from the width of the peripheral portion to be polished. Finally, the polishing unit is lowered to make the lower surface of the polishing member into pressure contact with the peripheral portion of the wafer, thus polishing only the peripheral portion. |
| US08066549B2 |
Method of producing rust inhibitive sheet metal through scale removal with a slurry blasting descaling cell having improved grit flow
A method is provided for removing iron oxide scale from sheet metal and producing a sheet metal surface with rust inhibitive properties. The sheet metal is advanced through the descaling cell and a slurry mixture is propelled against at least one of the top surface and bottom surface of the sheet metal across the sheet metal width as the material is advanced through the descaling cell. The rate of slurry impact against the at least one of the top surface and bottom surface of the sheet metal is controlled in a manner to remove substantially all of the scale from a surface of the sheet metal, and in a manner to create a passivation layer on the descaled surface of the sheet metal. The passivation layer comprises at least one of silicon, aluminum, manganese and chromium and inhibits oxidation of the descaled surface of the processed sheet metal. |
| US08066548B1 |
Multi-axes contouring machine and method of use
A multi-axes contouring machine for contouring a workpiece within a cavity of a main frame by moving a machining part along one or more axes simultaneously to the movement of the workpiece along one or more different axes. In an exemplary embodiment, the machining part simultaneously moves along an X and Y axis, while a workpiece moves along a Z axis. Here, the main frame comprises two adjacent side walls each having an opening cut out. A first carriage is attached to one of the side walls to move in the X direction, and a second carriage is attached to the first carriage to move in the Y direction. The machining part is actuated by the X and Y axes-oriented carriages. On another side wall, a carriage is attached to move in a Z direction, and the workpiece is actuated by the Z axis-oriented carriage. |
| US08066544B2 |
Toy apparatus and environment therefor
A toy apparatus may include a frame and a shell that may extend over and around the frame so that the apparatus takes on the appearance of an animal or thing. The frame may support a power source, a motor, drive and support wheel(s), a controller, one or more sensors and/or switches, and an audio emitting device(s). The sensor(s) and/or switches may include one or more of a photo sensor; a pressure, touch or contact sensor; an audio sensor; or any combination of these or similar sensors or switches that are positioned on the “front” and “top” of the frame. The apparatus may also be positioned in and interact with one or more separate or interconnected environments. These environments may include one or more platforms or enclosures, ramp(s), “exercise” wheel(s) and other light or sound emitting devices. |
| US08066529B2 |
Condenser connector for vehicle
Disclosed herein is a condenser connector for a vehicle, in which a condenser is installed at a position which is nearest or virtually nearest to a noise source, thus effectively eliminating or reducing noise. The condenser connector includes a housing having an insertion part. One end of a terminal is connected to a wire, and the other end thereof is fitted into and secured to one end of the insertion part. A holder is fitted into and secured to the other end of the insertion part. A condenser has a contact terminal which is in contact with the terminal, and is mounted to the holder. |
| US08066522B2 |
Apparatus for preventing electrical shock in devices
A device for preventing electrical shock from a device with electrical interfaces. A shutter or other barrier associated with the device that physically prevents access or contact to one of the electrical interfaces while another electrical interface is in use. |
| US08066520B2 |
Spark plug terminal connection apparatuses and methods
Apparatuses and methods are provided for conductively connecting a voltage source ignition cable to a spark plug terminal. A spark plug boot assembly is provided and can include a body member, a coiled terminal, and a voltage source ignition cable. The coiled terminal can have a first end, a second end, and a middle portion and can include one or more coils that can extend to form an inner area with the coils having a varying inside diameter. The first end can be configured to receive a spark plug terminal. Also, the voltage source ignition cable can be configured to provide an additional electrical contact to the coiled terminal. |
| US08066516B2 |
Coaxial connector
There is provided a coaxial connector having a good radio-frequency characteristic includes a main body having a hole, or opening for allowing a probe to be inserted, a fixed terminal is fixed to the main body, a movable terminal including a fixed portion fixed to the main body and a plate spring portion extending from the fixed portion toward the fixed terminal. The plate spring portion is in contact with the fixed terminal and in contact with the main body at its tips. The plate spring portion can be displaced by the probe in a direction away from the fixed terminal. |
| US08066512B2 |
Method for occlusal position measurement and recording
The occlusal position of a patient is measured by means of light transmission through a layer of a polysiloxane which is not cross-linked. This material forms an exceptionally accurate impression of a patient's bite essentially instantaneously and enables subsequent recording and analysis of the bite in a matter of minutes. |
| US08066509B2 |
Method and device for combusting hydrogen in a premix burner
A device for combusting fuel which contains or consists of hydrogen, is described, with a burner provided with a swirl generator and also a feeder for feeding fuel and a feeder for feeding combustion air into the swirl generator. A first feeder, for feeding liquid fuel along a burner axis, and a second feeder for feeding liquid fuel or gaseous fuel along air inlet slots which are tangentially delimited by the swirl generator, with a transition section connected downstream to the swirl generator, and with a mixer tube connected downstream to the transition section and with a changeable flow cross-sectional transition leads into a combustion chamber are provided. Along the transition section, a third feeder for feeding fuel which contains or consists of hydrogen, and also a fourth feeder for the selective feed of fuel which contains or consists of hydrogen, or of the gaseous fuel are also provided. |
| US08066508B2 |
Adaptive spark ignition and flame sensing signal generation system
A signal generation system for flame ignition and sensing. The ignition signal generation is adaptive for improving flame ignition while eliminating excess energy usage. High voltage signals for flame sensing may also be provided. If more energy or speed is needed for ignition signal generation, then the flame sensing signal generation portion may be disabled to increase the amount of available energy. Adaptation for ignition signal generation may be guided by the results of flame sensing. The flame sensing voltage may be regulated based on the flame current strength. The flame current may be controlled within an optimum range to reduce rod contamination rate and yet provide reliable flame sensing when the rod contamination built up. The adaptation may be algorithmic-based with the facilitation of a microcontroller. The system may provide the high voltage signals from a low voltage power supply, such as that of 24 VAC. |
| US08066505B2 |
Injection-molding nozzle
An injection molding nozzle comprises a material feed pipe subtending a flow duct communicating flow-wise with at least one nozzle tip. Each tip points transversely to axial direction A of the nozzle and is held by a manifold. The manifold is pluggable/insertable into the material feed pipe and includes a neck and a base. A manifold duct system is subtended in the manifold. A main duct extending the flow duct is in the neck and the base comprises a deflection site and at least one manifold duct. The manifold duct runs radially to axial direction A. The nozzle tip is affixed in a seating unit fitted with a central recess. Radial boreholes running transversely to axial direction A fit into the seating unit and receive plugged-in nozzle tips. The central recess receives the base, the nozzle tip being secured by the base to and in the seating unit. |
| US08066503B2 |
Controlled delta pressure bulk resin infusion system
A composite item is fabricated in a device for infusing a layup. The device include a mandrel, vacuum cup and bagging film. The mandrel is to receive the layup. The mandrel includes a reinforcement receiving zone and a resin receiving zone substantially adjacent to the reinforcement receiving zone. The vacuum cup is in cooperative alignment with the resin receiving zone. The bagging film is to generate a gas tight envelope surrounding the reinforcement receiving zone and the resin receiving zone. The vacuum cup is sealed upon the bagging film to generate a chamber above the resin receiving zone. |
| US08066502B2 |
Molding material feeding barrel and molding material feeding system
An exemplary molding material feeding barrel includes a main body, a blocking member, and an electrically conductive member. The main body has a chamber defined therein. The main body has a first inner surface in the chamber. The blocking member protrudes inward from the first inner surface of the main body. The electrically conductive member has a first end exposed at an inside of the main body, and a second end grounded. |
| US08066500B2 |
High pressure, high temperature back-up with a circumferential relief
In one aspect of the present invention, a cartridge assembly for connection to the frame of a high-pressure, high-temperature press comprises a front end comprising a back-up intermediate and coaxial with an anvil and a piston, the anvil comprising a proximal end in contact with the back-up and a distal end that forms part of a pressurized chamber within the frame, the back-up comprising a proximal end comprising a first diameter proximate an interface with a distal end of the piston, and a distal end comprising a second diameter proximate an interface with the proximal end of the anvil, the back-up comprising one or more circumferential reliefs disposed on the first diameter. |
| US08066495B2 |
Turbo vacuum pump and semiconductor manufacturing apparatus having the same
A turbo vacuum pump is suitable for evacuating a corrosive process gas or evacuating a gas containing reaction products. The turbo vacuum pump includes a casing having an intake port, a pump section comprising rotor blades and stator blades housed in the casing, bearings for supporting the rotor blades, a motor for rotating the rotor blades; and a rotating shaft comprising a first rotating shaft to which the rotor blades are attached, and a second rotating shaft to which a motor rotor of the motor is attached. |
| US08066493B2 |
Inflation aspirator with collapsible barrel
An aspirator for inflating an aircraft evacuation slide, emergency raft or other inflatable device includes a flexible, collapsible aspirator barrel that is inflated during operation to form a substantially rigid tube. According to one embodiment, the inflatable support member receives a flow of high pressure air directly from the aspirator injector nozzle assembly. According to another embodiment, the collapsible aspirator barrel receives a flow of high pressure gas directly from the high pressure inflation source. Because the aspirator barrel of the present invention is collapsible, the present invention occupies significantly less space when stored than an equivalent aspirator with a rigid aspirator barrel. |
| US08066491B2 |
Reciprocating pump with electronically monitored air valve having battery and solenoid electronic monitoring
An air operated pump (10) uses a magnet (14) mounted in the valve cup (16) of the air motor (18) and two reed sensors (20) mounted in the valve cover (22) to monitor the speed and position of the valve (16). A solenoid (24) is mounted on the valve cover (22) and can be commanded to extend a plunger (26) into the valve cup (16) to stop valve movement and therefore the pump from running away. Three methods may be used to increase battery life and monitor the solenoid plunger position, two of which use the changing inductance of the solenoid (24) to monitor the solenoid movement. |