Document Document Title
US07817063B2 Method and system for remotely monitoring and controlling field devices with a street lamp elevated mesh network
An elevated mesh network supported and operably coupled to street lamps can be used to remotely monitor and control field devices. The packet transceiver modules of the mesh network can also be coupled to sensors that monitor operation of a street lamp as well as environmental conditions. The elevated mesh network supported by street lamps can use RF links to couple with one or more remote field devices that also have packet transceiver modules. The elevated mesh network can also include a communications gateway that couples the elevated mesh network to an asynchronous communications system. The communications gateway is a store and forward system that can periodically connect to the asynchronous communications system in order to upload compressed data derived from the remote field devices. The asynchronous communications system can connect the elevated mesh network to a back-end computer system that may monitor, diagnose, and control the remote field devices.
US07817060B2 Electrical control system
An electrical control system includes one or more master nodes that are adapted to control and monitor the operation of one or more slave nodes. The master nodes and the slave nodes are operably coupled by one or more communication interfaces, such as radio frequency, Internet Protocol, power line, or other conventional communication interfaces. A hand-held radio frequency controller includes a controller that is operably coupled to an radio frequency transceiver. The controller includes an operating system and application programs, including a device engine, a scenes engine, an events engine, a system engine, and an away engine. The device engine, scenes engine, events engine, system engine and away engine permit a user of the hand-held radio frequency controller to customize the operation of at least some of the aspects of the master and slave nodes.
US07817058B2 Server signaler
A server signaler includes a lamp and a housing containing a battery and a switch. The server signaler may be attached to an advertising support or placed directly on a table top or other surface. Actuation of the switch illuminates the lamp to alert the server that service is required. Another server signaler according to applicant's invention includes an elongated base and telescoping portions to extend the lamp upwardly above the elongated base. Another server signaler provides a card-receiving channel containing switch contacts which are closed by insertion of a card into the channel.
US07817049B2 Combined scattered-light and extinction-based fire detector
A fire detector has at least two sensor units for monitoring a confined space for the occurrence of a fire. A first fire parameter is monitored according to the scattered light method, using a first sensor unit located at or in the vicinity of the ceiling. At least one second sensor unit of the fire detector, which emits at least two highly focused light beams towards the floor of the confined space, monitors a second fire parameter according to the extinction method.
US07817046B2 Method and apparatus for cataloging and poling movement in an environment for purposes of tracking and/or containment of infectious diseases
A system and method for containing and restricting spread of infectious diseases within hospitals, clinics and other medical facilities by cataloguing and delimiting movement of patients, medical staff, employees, visitors, contractors and other personnel attending or on-site. The system also provides for tracking and cataloguing contaminated medical apparatus, medicine trolleys, food trolleys, medical gas stations, laundry baskets and other mobile or movable medical equipment or facility equipment to prevent spread of the infectious disease or viral entities. According to another aspect, the system includes a poling or supervisory network for auditing the presence or absence of patients, medical staff and other personnel; and medical apparatus, movable equipment or other facility equipment.
US07817043B2 Radio frequency tag
The present invention provides an RF tag which does not have an integrated circuit such as a silicon chip, can retain a plurality of information, can rewrite or add the information, and is inexpensive. The RF tag includes an RF resonance circuit which has at least two capacitors connected in series or parallel and at least one coil antenna formed on a substrate, wherein at least one of the capacitors is an anti-fuse which irreversibly short-circuits when a voltage higher than a threshold voltage is applied to the anti-fuse, and the surface of an electrode constituting the capacitor has a mean roughness of 1 μm or less.
US07817040B2 RFID transducer alignment system
A radio frequency identification (RFID) system having the capacity to detect conditions of alignment, wherein the system may be used with hand-held, fixed-in-place, stationary, and permanently mounted apparatus. The system includes an RF interrogator configured for use with dental x-ray, medical imaging, film, and digital radiography apparatus, and may include a multiplicity of RF transponders or interrogators. An RF interrogator, an RF transponder, and an x-ray sensitive imaging device, and its holder are configured to be critically aligned to a dental x-ray machine head apparatus, rendering repeat imaging unnecessary. The x-ray emitter may be further configured to automatically obtain a desired x-ray image or configured so that the device cannot activate and provide a radiograph until alignment with the transponder and associated x-ray sensitive imaging device has occurred.
US07817037B2 Electronic component with ID tags
The invention relates to an electronic component that can be operated by means of an alternating voltage. Said component includes at least one input, at least one output and a pair of electronic sub-components with an identical function. The input(s) of the electronic component is/are coupled to a respective input of the electronic sub-components with an identical function and the output(s) of the electronic component is/are coupled to a respective output of said electronic sub-components. In addition, the electronic component is configured in such a way that at least one output only one output signal of the first sub-component of the pair of functionally identical electronic components can be picked up during a first half-wave of an alternating voltage, whereas only one output signal of the second sub-component of the pair of functionally identical electronic can be picked up during the second half-wave of the alternating voltage.
US07817036B2 Cabled and cableless interface method for connecting units within a rack
A system and method for automatically determining a physical location of one or more units in a rack, including: using one or more physical cables between rack units; cascading a first signal through the one or more units located in the rack, the first signal being encoded with a unit number and a physical parameter; and creating a rack ID by utilizing hardware parameters, the hardware parameters being determined by: detecting a second signal that exists from a bottom unit, the bottom unit located at the bottom of the rack; and using a third signal to send data between the one or more units in the rack by manipulating void spaces within the rack, the third signal being either cabled or an optical signal.
US07817034B2 Inventory monitor for an article dispenser
A monitoring system for developing information data, for use in association with an opening that provides access for removal by a customer of articles stored in an article storage area. In one embodiment, the monitoring system includes a beam forming device adapted to be arranged about the perimeter of the opening so as to form at least one radiation beam that spans the opening. The radiation beam has a position with respect to the opening that is sufficient to detect manual removal by the customer of one or more of the articles from inside the article storage area, by the article and hand of the customer causing a temporary blockage of at least a portion of the radiation beam as the article and hand of the customer pass through the opening. A processing circuit coupled to the beam forming device senses the blockage of the radiation beam, and in response to the sensing, develops the information data.
US07817033B2 Vehicle locating method and system using a mobile device
A system to transmit a location of a vehicle, including: a transmission system including, a first system unit configured to determine a current location using radio signals, a first memory unit storing a database that includes a list of one or more mobile devices, a processor configured to select one of the mobile devices from the database, and a first transmission unit configured to transmit the current location to the selected one of the mobile devices in response to an engine of the vehicle being shut off.
US07817029B1 Method for remote pre-verification of alarm signals and remote alarm system control
A method of alarm data communication involves protecting a premise with an alarm sensor, sensing an exception, text messaging a responsible user's text-messaging device a text message indicative of such exception and, in the absence of an effective cancel instruction, propagating a signal to a central alarm monitoring station indicative of such exception or otherwise expediting dispatch of authorities to the premise in response to such exception. Another aspect of this method involves that, notwithstanding the absence of an effective cancel instruction, there instead might be the issuance of an effective verify instruction, which propagates to the central alarm monitoring station as indicative of not only the exception but also that such exception is verified.
US07817027B2 Method and system for integrated media and vehicle seat belt monitoring
The present invention is, in one embodiment, directed to a system and method to encourage seat belt use among all passengers in a vehicle. The system and method use media driver and entertainment devices to reward seat belt usage in all seating positions.
US07817025B2 Apparatus for detecting vehicle wheel positions based on reception intensities of triggering signals outputted simultaneously
In a vehicle's wheel position detecting apparatus, a first triggering device, attached to the vehicle's body, outputs a triggering signal including information indicating that the triggering signal is for front wheels. A second trigging device, attached to the body, outputs a triggering signal including information indicating that the triggering signal is for rear wheels. The first and second triggering devices output the triggering signals simultaneously. A transceiver is attached to each of the front and rear four wheels. Each transceiver receives the triggering signal, calculates a reception intensity of the triggering signal, stores both the reception intensity data and the information into a frame, and transmits the frame. A receiver, attached to the body, receives the frame and processes the received frame to read out both the data and the information and use the read-out data and information to detect the positions of the wheels.
US07817024B2 Vehicle tire warning system
An air pressure sensor (2) for a vehicle tire warning system includes a tubular housing (21) defining a chamber (218), an air pressure actuating device seated in the chamber and being moveable back and forth in the chamber in response to air pressure change in the vehicle tire, and a switch device to electrically connect a high air pressure warning circuit or a low air pressure warning circuit under the drive of the air pressure actuating device. The chamber of the tubular housing is communicated to the atmosphere via a connecting pipe (29).
US07817022B2 Vision enhancement device for use in vehicle
A vision enhancement device for use in a vehicle that improves the frontward vision of an operator during operation. The device has two dividing lines set apart from each other on an instrument panel. These dividing lines show as false image lines on an inside surface of a front window, and divide the inside surface of the front window into a plurality of areas in a vertical direction. A second area formed between these two false image lines forms an appropriate visual field range when the operator looks forward while operating the vehicle. First light emitting means comprising light emitting diodes are disposed at both ends of each of the two dividing lines. The light emitted by these light emitting diodes is directed onto the front window as a false image in accordance with changes in the vehicle state and the environment around the vehicle.
US07817015B1 Floating threshold for data detection in a RFID tag
A radio frequency identification (RFID) tag is provided with a capability to adaptively initiate a floating RF threshold from the level of a raw RF signal detected during a communication session with a designated RFID reader, and to compare that threshold with the level of a baseband signal derived from the RF signal so as to reject RF interference including noise from other sources during the communication session. Preferably, the threshold is derived from the peak level of the detected RF signal on commencement of each communication from the reader during the session.
US07817009B2 LED apparatus with temperature control function
An LED apparatus with temperature self-regulating, over-temperature protection, and over-current protection function comprises an LED chip, a heat dissipation plate, a heat conductive layer and a temperature control device. The heat dissipation and the heat conductive layer disposed thereon carry the LED chip and dissipate the heat generated from the LED chip that is connected to an electric power source for luminance. The temperature control device exhibiting PTC behavior is electrically connected between the LED chip and the electric power source in series, and the distance between the LED chip and the temperature control device is less than 3 cm. The heat conductive layer can consist of polymeric dielectric material and has a heat conduction coefficient larger than 1.0 W/mK at 25° C.
US07817008B2 Magnetic element
A magnetic element includes a pair of coil sets. Each of the coil sets includes a first coil having a plurality of first metallic lines, a second coil having a plurality of second metallic lines, and at least one conductive column electrically connected between the first coil and the second coil. The magnetic element further includes a package body for enclosing the pair of coil sets therein.
US07817005B2 Correlated magnetic container and method for using the correlated magnetic container
A correlated magnetic container and method are described herein that use correlated magnets to enable a container having at least two sections to be assembled, disassembled or releasably secured to an external object. Some examples of the two sections of the container that can be assembled and disassembled utilizing the correlated magnets include a wall panel, top panel, side panel, bottom panel, door panel, a handle, a tool, a belt, a frame member or locking member.
US07817004B2 Correlated magnetic prosthetic device and method for using the correlated magnetic prosthetic device
A prosthetic device is described herein that incorporates correlated magnets which enable an artificial prosthesis (e.g., artificial limb) to be easily and effectively attached to and removed from an interface that is secured to a residual limb on a person. In addition, a method is described herein for enabling a person to attach and remove an artificial prosthesis to and from an interface that is secured to a residual limb on the person.
US07817000B2 Selectively configurable relay
A relay, in particular for radio-frequency applications, has at least one first contact electrically connected with a first conductor trace, the first contact in a contact position can be selectively electrically connected by a mechanical actuator with at least two second contacts electrically connected with at least one second conductor trace. The relay has a spatially fixed first circuit board with the first contact and the first conductor trace and a second circuit board with the second contacts and the second conductor trace that can be moved against the first circuit board into various contact positions by the mechanical actuator.
US07816993B2 Temperature compensated crystal oscillator
The present invention relates to an integrated circuit for a temperature compensated crystal oscillator having an external crystal. The integrated circuit comprises a temperature compensation having one fixed or at least two selectable 3rd and/or 4th and/or 5th and/or higher order temperature compensation functions for at least one specific type of external crystal. The temperature compensation can be calibrated at one temperature, in other words without use of temperature variation, by means of an external voltage or current source overdriving a respective temperature-dependent voltage or current supplied from an internal temperature sensor to the temperature compensation.
US07816992B2 Offset voltage correction circuit and class D amplifier
An offset voltage correction circuit for a differential amplifier comprising NMOS transistors serving as a pair of differential transistors, and PMOS transistors serving as a pair of load transistors connected between outputs of the pair of differential transistors and a power source. The offset voltage correction circuit is equipped with a voltage generator for generating, between a source of any one of the pair of load transistors and the power source, a constant voltage for correcting an offset voltage of the differential amplifier.
US07816991B2 Signal splitter
A controllable-gain circuit (TI, Rt, TS1, . . . , TS4) provides a first and a second pair of complementary gain-controlled signals (Ip1, Ip3; Ip2, Ip4) in response to an input signal (RFI). In each pair, one gain-controlled signal (Ip1, Ip2) is the input signal amplified with a gain G comprised in a range between a minimum gain Gmin and a maximum gain Gmax. The other gain-controlled signal (Ip3, Ip4) is the input signal amplified with complementary gain Gmax-G. A fixed-gain output circuit (Rfg, Nfg) makes a weighed sum (Ip1*Rfg+Ip3*Rfg) of one and the other gain-controlled signal in the first pair of complementary gain-controlled signals. The respective weighing factors for one and the other gain-controlled signal are substantially similar (Rfg). A controllable-gain output circuit (Rlg, Rhg, Nlg, Nhg) makes a weighed sum (Ip2*Rlg+Ip4*(Rlg+Rhg)) of one and the other gaincontrolled signal in the second pair of complementary gain-controlled signals. The respective weighing factors for one and the other gain-controlled signal are substantially different (Rlg, Rlg+Rhg).
US07816990B2 Variable gain amplification circuit
A variable gain amplification circuit comprises a signal generator that has an output terminal and is able to vary an output amplitude; a variable capacitor connected between the output terminal and an AC grounded terminal; and a control circuit for controlling the output amplitude of the signal generator, and a capacitance of the variable capacitor. Therefore, unnecessary signals can be attenuated even when the gain is low, and degradation in distortion characteristics in the latter block can be suppressed.
US07816987B2 Driver circuit and driver IC
A driver circuit comprises: differential amplification stages connected in series, and at least two cross-point adjuster circuits respectively connected to at least two differential amplification stages of the differential amplification stages. The cross-point adjuster circuits control at least one of the positive-phase and negative-phase DC levels of a corresponding differential amplification stage and adjust the cross point of the output signals of the corresponding differential amplification stage.
US07816986B2 Output stage circuit
A PWM signal drives a pair of output transistors connected in series between a supply line and ground so that a push-pull current is output toward a speaker via a coil from a point connecting both output transistors. A current limiting resistor has one end connected to the supply line and between the other end and ground is provided a control transistor. Furthermore, a comparator compares the supply line voltage and a reference voltage and turns on the control transistor when the supply line voltage is higher than the reference voltage in the comparison result thereof.
US07816982B2 Switching audio power amplifier with de-noise function
The invention provides a switching audio power amplifier with de-noise function, including a first comparator, a second comparator, a logic control unit, a de-noise circuit, and a bridge circuit. The first comparator and the second comparator respectively generate the first PWM signal and the second PWM signal, and then the logic control unit performs logic operation to generate a third PWM signal and a fourth PWM signal. If the pulse width of the third PWM signal (or the fourth PWM signal) is lower than a threshold, the de-noise circuit increases the pulse width of the third PWM signal or the fourth PWM signal and outputs the fifth PWM signal and the sixth PWM signal to drive the bridge circuit. Next, the bridge circuit conducts a driving current alternately flowing to and from a load according to the firth PWM signal and the sixth PWM signal.
US07816981B2 Signal generating apparatus and class-D amplifying apparatus
A signal generating apparatus includes: a data generator which generates a data series in which first, second, third and fourth data are arranged at a sampling period; a first signal generator which generates a first pulse-width modulation signal in which a pulse is arranged in a pulse period longer than the sampling period, time points of front and rear edges of the pulse being set in response to the first and second data; and a second signal generator which generates a second pulse-width modulation signal in which a pulse is arranged between the adjacent pulses of the first pulse-width modulation signal, time points of front and rear edges of the pulse of the second pulse-width modulation signal been set in response to the third and fourth data, respectively.
US07816977B2 Core voltage generator
Core voltage generator including a comparison unit configured to compare a reference voltage with a feedback core voltage to output a difference between the reference voltage and the feedback core voltage, an amplification unit configured to output a core voltage by amplifying an external power supply voltage according to an output signal of the comparison unit and a mute unit configured to maintain a voltage level of an output terminal of the amplification unit at a ground voltage level when the output of the core voltage is interrupted.
US07816976B2 Power supply circuit using insulated-gate field-effect transistors
A power supply circuit is disclosed. The power supply circuit is provided with a reference voltage generation circuit to receive a voltage from a higher voltage supply so as to generate a reference voltage. The reference voltage from the reference voltage generation circuit is outputted to a power supply voltage generation circuit. The power supply voltage generation circuit boosts the reference voltage to generate a boosted power supply voltage. The boosted power supply voltage is inputted to a bandgap reference circuit. The bandgap reference circuit generates a reference voltage by using the boosted power supply voltage.
US07816973B2 Devices and methods for reducing effects of device mismatch in temperature sensor circuits
A temperature sensor having one or more mirror circuits output temperature dependent output signals is disclosed in one embodiment. The temperature sensor includes a sampling circuit coupled to receive a clock signal that samples the output signals for a duration of a predetermined number of clock cycles. The temperature sensor additionally includes a phase control circuit that receives the clock signal and generates a control signal that enables subsequent sampling operations. Each subsequent sampling operation has a duration of the predetermined number of clock cycles. The control signal from the phase control circuit further enables input and output terminals of respective circuit components in the mirror circuits to be switched for each subsequent sampling operation.
US07816972B2 Multiplexer circuit
Disclosed herein is a multiplexer circuit. The multiplexer circuit includes a first differential output unit, a second differential output unit, and a selection unit. The first differential output unit receives NRZ input signals (D1 and D1) and a clock signal (CLK), and generates differential RZ-mode outputs (R1 and R1). The second differential output unit receives NRZ input signals (D2 and D2) and an inverted clock signal ( CLK), and generates differential RZ-mode outputs (R2 and R2). The selection unit receives the RZ-mode output signals (R1, R1, R2, and R2) generated at the first differential output unit and the second differential output unit, and generates NRZ mode outputs in each half cycle of the clock signal (CLK).
US07816971B2 Switch circuit having adjustable linearity of differential mode resistances
A switch circuit includes a pair of metal oxide semiconductor (MOS) switches and an adjusting unit. Each of the MOS switches has an input terminal and an output terminal. The MOS switches receive a pair of differential input voltages at the input terminals thereof, and output a pair of differential output voltages at the output terminals thereof when the MOS switches conduct. The adjusting unit changes a difference between common mode levels of the input terminals and the output terminals of the MOS switches so as to adjust linearity of differential mode resistances of the MOS switches.
US07816970B2 Low voltage mixer with improved gain and linearity
A frequency mixing apparatus with improved voltage gain and linearity is provided. The frequency mixing apparatus includes a transconductor, a separator, and a switching unit. A voltage gain of the transconductor is controllable, and the transconductor converts a Radio Frequency (RF) signal into a current signal under control of a self bias. The separator transfers the current signal to the switching unit. The switching unit outputs a signal having a frequency corresponding to one of a sum and a difference of a frequency of the RF signal and a frequency of a Local Oscillation (LO) signal by performing a switching operation according to the LO signal.
US07816969B2 Level shifter circuit
A level shifter circuit is disclosed. The circuit receives a digital input signal characterized by a logical high state having a first high voltage level and generates an output node for driving a digital output signal characterized by a logical high state having a second high voltage level. The output signal logical state mirrors the input signal logical state. The circuit includes a short circuit current reduction mechanism for charging a first internal node of level shifter circuit following a first transition of the input signal logical state. The circuit further includes a performance enhancement mechanism for discharging the first internal node of the level shifter circuit following a second transition of the input signal logical state. The performance enhancement mechanism may comprise a transistor driven by the input signal and connected between the first internal node and ground. The current limiting mechanism may comprise a transistor having a source/drain terminal connected to the first internal node.
US07816965B2 Cooperation circuit
The present invention discloses a cooperation circuit, comprising: a first control module, capable of generating a first control signal and a second control signal, the pulse width of the first control signal being determined by the pulse width of the second control signal; and a second control module, coupled to the first control module to receive the first control signal and the second control signal and generate a third control signal according to the first control signal and the second control signal; wherein, according to the first control signal and the second control signal, the second control module enables the third control signal and the second control signal to exhibit the same frequency and the same duty cycle with a phase delay.
US07816963B1 Phase interpolator with adaptive delay adjustment
The phase interpolator includes two adjustable delays 30 and 31, phase comparator 32 which detects a phase difference between a signal delayed by the adjustable delay 30 and a signal delayed by the adjustable delay 31, an integrator 33 which integrates the outputs of the phase comparator 32 and multipliers 34-1 and 34-2 which set a control voltage for the adjustable delays 30 and 31. The feedback loop comprising phase comparator 32 and integrator 33 controls a delay amount of the adjustable delay 30 thereby securing a phase relation between {ACK1, ACK2} and ICK to achieve a stable ICK phase.
US07816962B2 Delay locked loop with improved jitter and clock delay compensating method thereof
A delay locked loop can remove a jitter component that inevitably occurs due to feedback latency in the conventional DLL. That is, the present invention has benefit of removing the jitter component by controlling the delay lines based on the predicted data. The delay locked loop includes a pattern detecting unit for generating and storing a noise pattern by detecting inputted noise data, a pre-delay control unit for determining a delay amount depending on the output of the pattern detecting unit, and a pre-delay line for delaying an internal clock depending on the delay amount that is determined by the pre-delay control means.
US07816959B1 Clock circuit for reducing long term jitter
A clock circuit generates a reference clock signal based on a resonant frequency of a crystal, generates thermometer-coded signals based on the reference clock signal, and generates a pulse train based on the thermometer-coded signals. The pulse train has a frequency that is a multiple of the frequency of the reference clock signal. Additionally, the clock circuit includes a phase-lock loop for generating an output clock signal based on the pulse train and aligning a phase of the output clock signal with pulses in the pulse train. In various embodiments, the frequency of the reference clock signal is the same as the resonant frequency of the crystal and the frequency of the output clock signal is a multiple of the resonant frequency of the crystal. Moreover, reference clock signal and the output clock signal each have a long-term jitter based on the precision of the resonant frequency of the crystal.
US07816955B2 Ramp generator and circuit pattern inspection apparatus using the same ramp generator
The present invention provides a ramp generator capable of appropriately setting a rise starting point of an output voltage of a ramp waveform and an output voltage at the time of stable output. A current adjustment unit including a differential pair of transistors and an amplifier constitute a feedback circuit. By controlling the charging/discharging of an integration capacitor by ON/OFF of a discharge current source connected to a common emitter terminal of the current adjustment unit, an output of the ramp waveform outputted from an output terminal disposed at the connection end of the integration capacitor is controlled.
US07816954B2 Circuit configuration of a frequency divider
A frequency divider including at least one frequency divider cell having an adjustable circuit configuration which may be selected adaptively according to properties of an oscillator signal to be frequency-divided in the frequency divider. Accordingly, the circuit configuration of the frequency divider may be changed on the fly during the operation.
US07816952B2 Clock signal switching device, clock signal switching method, data bus switching device, and data bus switching method
A clock signal switching device includes: a plurality of signal synchronization generation means for generating mask signals and synchronized switching signals; a plurality of clock signal mask means for generating masked clock signals; a synchronized switching signal selection means for selecting one from among the synchronized switching signals; and a masked clock signal selection means for selecting one from among the masked clock signals.
US07816951B1 Locally boosted top plate sampling for a sampling capacitor
An analog sampling network (100) includes a sampling capacitor being coupled between a bottom plate sampling switch and a top plate sampling switch implemented as NMOS transistors. The top plate sampling switch has source/drain terminals coupled respectively to the sampling capacitor and a first reference voltage. The analog sampling network includes a top plate boosting circuit (150) providing a boosted gate voltage to a gate terminal of the top plate sampling switch during a sampling phase, the boosted gate voltage being the sum of a first voltage and a second voltage. The first voltage is approximately equal to the first reference voltage and tracks process, temperature, power supply voltage and biasing condition variations. The second voltage is a maximum operating voltage from the gate to drain/source terminal for a fabrication process used to fabricate the second MOS transistor.
US07816949B2 Signal transmission circuit and signal transmission system using the same
A signal transmission circuit includes first and second power source wirings, and a plurality of differential circuits connected in series between the first and second power source wirings. A signal transmission system includes a plurality of pairs of signal wirings, an output circuit supplying a differential signal to each of the pairs of signal wirings, and an input circuit receiving the differential signals via the pairs of signal wirings, wherein the output circuit includes first and second power source wirings, and a plurality of differential output circuits connected in series between the first and second power source wirings, and the input circuit includes a plurality of differential input circuits respectively corresponding to the differential output circuits.
US07816945B2 3D chip-stack with fuse-type through silicon via
Programmable fuse-type through silicon vias (TSVs) in silicon chips are provided with non-programmable TSVs in the same chip. The programmable fuse-type TSVs may employ a region within the TSV structure having sidewall spacers that restrict the cross-sectional conductive path of the TSV adjacent a chip surface contact pad. Application of sufficient current by programming circuitry causes electromigration of metal to create a void in the contact pad and, thus, an open circuit. Programming may be carried out by complementary circuitry on two adjacent chips in a multi-story chip stack.
US07816944B2 Variable width writing to a memory of an IC
Some embodiments of the invention provide a configurable integrated circuit (“IC”). This IC includes several configurable circuits for receiving configuration data and configurably performing a set of operations based on the configuration data. It also includes several hybrid circuits. Each particular hybrid circuit can interchangeably perform as either a logic circuit or an interconnect circuit in the configurable IC.
US07816942B2 USB 2.0 HS voltage-mode transmitter with tuned termination resistance
A high-speed universal serial bus (USB) transceiver includes a voltage-mode architecture for generating a USB signal. The voltage mode architecture reduces power consumption by reducing the current requirements for high-speed USB communications. The USB transceiver can include a reference voltage generator, a resistive element, and a switching element for completing and breaking a circuit including the reference voltage generator, the resistive element, and a data pin of a USB port to generate half of the differential USB signal (e.g., the D+ signal). A similar circuit can be used to generate the other half of the differential USB signal (i.e., the D− signal). The resistive element can be a set of parallel resistors in the transceiver, with the set of parallel resistors being specifically selected from a larger population of resistors to provide the specified resistance (45Ω±10%) in the USB transceiver.
US07816936B2 Apparatus for controlling substrate voltage of semiconductor device
A semiconductor integrated circuit apparatus includes an internal circuit having a MIS transistors on a semiconductor substrate and a substrate voltage control block that supplies a substrate voltage to the internal circuit and controls threshold voltages for the MIS transistors of the internal circuit. The apparatus also includes a leakage current detection MIS transistor and a leakage current detection circuit. The substrate voltage control block generates a substrate voltage based on comparison results of the comparator and applies the generated substrate voltage to the substrate of the leakage current detection MIS transistor and the substrate of the MIS transistors of the internal circuit. The substrate voltage control block includes a switch arranged between first and second input terminals of a comparator and a drain of the leakage current detection MIS transistor and a reference potential terminal, as well as an input data corrector that carries out substrate voltage adjustment.
US07816933B2 Semi-generic in-circuit test fixture
A semi-generic test fixture for testing printed circuit boards (PCBs) and/or for testing printed circuit boards assemblies (PCBAs) is presented. The semi-generic test fixture implements a combination of generic and customized parts for tester-to-fixture interface instead of a static dedicated in-circuit test (ICT) fixture which is able to interconnect only one kind of unit under test (UUT) to an ICT tester test-head. The semi-generic ICT fixture (SGICTF) is able to interconnect an ICT test-head with a variety of UUT types with a minimum of adaptation. Accordingly, the SGICTF generally comprises two generic PCB connected to the tester and two customized PCB connected to the generic PCB and adapted to interface the particular UUT via testing probes.
US07816930B2 High temperature range electrical circuit testing
An electrical circuit testing assembly that includes a mechanical reference that is relatively stationary as compared to a circuit under test. A probe support assembly is coupled to the mechanical reference and includes probes for contacting interconnect pads on the circuit under test. Optionally, the probe support structure is attached to the mechanical reference via a column that is thermally resistive. Also optionally, a testing circuitry support structure (e.g., a printed circuit board) is not rigidly attached to the mechanical reference or to the probe support structure, thereby permitting the testing circuitry support structure to float with respect to the probe support structure.
US07816929B2 Socket and electronic appliances using socket
The present invention is made with the aim of suppressing heat generation and thus reducing voltage drop, regarding a socket comprising probes to be connected to an electronic device such as an IC package. This is achieved by the socket 6 comprising heatsink components (heatsink plates 74, 76, 201, and 202) disposed adjacent to probes 32, 34, 36 so that the heatsink components move heat of the probes to a heatsink area 84. The socket 6 includes an air layer AL encompassing at least heat-generating portions 104 and 106 in the probes. The heat-generating portions are extended to the side of the socket 6 and heatsink fins (heatsink slit 86) are formed at its end portion. The socket 6 comprises a first probe 32 to be connected with pressure between an electrode (electrode pad 26) of signal system in the electronic device (IC package 4) and an electrode (electrode pad 44) of a signal extraction board 38 corresponding to the signal system; and second probes 34 and 36 to be connected with pressure between electrodes (electrode pads 28 and 30) of power system in the electronic device and an electric conductor (conductive plates 40 and 42) corresponding to the power system.
US07816928B2 Determination of equivalent series resistance
A determination of an equivalent series resistance (ESR) effect for high frequency filtering performance of a filtered feed-through assembly is described. A low frequency signal is introduced to a filtered feed-through assembly. ESR limit of the filtered feed-through is determined based on the low frequency signal.
US07816927B2 Method and system for real time identification of voltage stability via identification of weakest lines and buses contributing to power system collapse
A method of identifying voltage instability in a power system via identification of a weakest line and bus that contribute to the collapse of the system is provided. The method includes periodically calculating an extended line stability index for the transmission lines monitored in the power system; and using the extended line stability index to determine the distance of an operation state in the power system from a collapse point of the system caused by voltage instability.
US07816926B2 High frequency circuit analyser
An analyzer for measuring the response of an electronic device (DUT 206) to an RF input signal from a signal generator (240a) is described. An active load pull circuit (201) is connected to the DUT 206, which receives an output signal from the DUT 206 and then feeds a modified signal back to the DUT 206. The signal is modified by a signal processing circuit (237) in view of input signals x, y to control the magnitude gain and phase change effected by the feedback circuit (237). Thus, positive feedback loops are avoided and better control of the analyzer is permitted. A network analyzer, or other signal measuring device (242), logs the waveforms (from which s-parameters derived) observed at ports of the DUT 206, thereby allowing the behavior of the DUT 206 under various load conditions to be analyzed.
US07816922B2 Magnetization of target well casing string tubulars for enhanced passive ranging
A method for magnetizing a wellbore tubular is disclosed. The method includes magnetizing a wellbore tubular at three or more discrete locations on the tubular. In exemplary embodiments the magnetized wellbore tubular includes at least one pair of opposing magnetic poles located between longitudinally opposed ends of the tubular. Wellbore tubulars magnetized in accordance with this invention may be coupled to one another to provide a magnetic profile about a section of a casing string. Passive ranging measurements of the magnetic field about the casing string may be utilized to survey and guide drilling of a twin well. Such an approach advantageously obviates the need for simultaneous access to both wells.
US07816920B2 Metal detector
An exemplary metal detector includes a detecting circuit, a SCM, a converting circuit, and a cymometer. The SCM cooperates with the detecting circuit to generate a current signal with a specific frequency, the converting circuit transforms the current signal received from the SCM to a voltage signal, and the cymometer displays a value of a frequency of the current signal according to the voltage signal. When the detecting circuit detects a metal nearby, the value of the frequency of the current signal displayed on the cymometer changes.
US07816917B2 Permeability measurement apparatus
A permeability measurement apparatus includes a magnetic field generation means applying an alternating magnetic field having a predetermined frequency to a magnetic substance to be measured; a probe needle placed in proximity or in contact to a microscopic area of the magnetic substance to be measured to which the alternating magnetic field is applied; a resonator including a coil wound on the probe needle, and generating a magnetic field having a resonant frequency higher than the frequency of the alternating magnetic field applied on the microscopic area having the probe needle in proximity or in contact thereto, and having an inductance of the coil varied as permeability in the microscopic area varies; and a measurement means measuring the permeability of the microscopic area of the magnetic substance to be measured based on the variation of the resonant frequency of the resonator according to the variation of the coil inductance.
US07816916B2 Magnetic resonance imaging method using a parallel imaging technique combined with a zoomed acquisition technique
In a magnetic resonance imaging method and apparatus, magnetic resonance data are acquired (an examination subject) using a zoomed method, and reconstruction of the image of the examination subject is undertaken using a parallel imaging reconstruction method.
US07816908B2 Display device and liquid crystal television
The present invention discloses enabling readily determining which circuit, among a plurality of circuits including an optical source lighting circuit and a power supply circuit, has a failure and repairing the circuits easily in a short period. A liquid crystal television 100 comprising a power supply circuit 24 that produces and outputs various power supply voltages from an inputted commercial AC power supply, a microcomputer 22 that outputs a control signal to a plurality of circuits, respectively, including at least the power supply circuit 24 and an inverter circuit 26 that is driven by a power supply voltage output by the power supply circuit 24 to controls turning on and off of each circuit, is provided with an input terminal 53 for providing a power supply voltage from the outside of the liquid crystal television 100, and an inspection auxiliary circuit 50 connected to the power supply circuit 24 and inverter circuit 26, generating a constant voltage that starts the power supply circuit 24 and inverter circuit 26 when a power supply voltage is provided from the input terminal 53 and outputs the constant voltage as a control signal.
US07816906B2 Method for determining anisotropy of 1-D conductor or semiconductor synthesis
A method is provided for determining the anisotropy of alignment of a random array of 1-D conductive elements (e.g., carbon nanotube or silicon nanowire) formed on a substrate. A pattern of a plurality of electrodes are arranged on the substrate containing the 1-D conductive elements and a plurality of electrical property measurements are performed in a plurality of different directions between the plurality of electrodes. The plurality of measurements are combined together to generate a total measurement sum of electrical property measurements between the various electrodes. The measured electrical property is determined between a selected pair of the plurality of electrodes along a selected direction extending between the selected pair of electrodes. The anisotropy of alignment of the 1-D conductive elements on the substrate along the selected direction is determined based on a ratio of the measured electrical property between the selected pair of electrodes versus the total measurement sum.
US07816904B2 Modulation signature trigger
A trigger generator and trigger method are provided for determining whether or not a signal under test matches a modulation signature. The modulation signature may be provided as a magnitude signature, a phase signature or both. When the magnitude values, phase values, or both of a signal under test are the same as their respective modulation signature, an error computation will be close to zero. If this value is within a threshold value, a trigger signal or other indication of a match is produced.
US07816901B2 PWM modulator for scalable converters
A PWM modulator for generating a PWM control signal for operating transistor switches of a phase of a multi-phase converter including a plurality of ramp generators, each ramp generator receiving a dedicated clock input signal corresponding to a phase of the multi-phase converter and providing a ramp signal starting when the dedicated clock signal is received by the ramp generator, one of the plurality of ramp generators being dedicated to provide the PWM control signal; a plurality of comparators, each comparator associated with a respective ramp generator for terminating the ramp signal when a predefined inequality exists between an error amplifier output of a feedback loop of the multi-phase converter and an output of the associated ramp generator; a plurality of current generator circuits, each current generator circuit associated with a respective ramp generator for providing current to the dedicated ramp generator to control the slope of the ramp signal of the dedicated ramp generator, the dedicated ramp generator controlling its associated comparator to provide the PWM control signal; and a plurality of current generator control circuits for controlling the operation of the plurality of current generator circuits.
US07816899B2 Power conversion device
In a power conversion device having high side and low side switches connected to a coil, a direction of a coil current is determined during a dead time period where the respective switches turn off at the same time to make the increase/decrease ratio of the coil current correspond to a command value. Based on a direction detection signal and a PWM signal of a PWM signal generation unit, an operation mode of a power converter circuit is determined, and a ratio correction value and an offset value of the PWM signal is set with respect to a control period of the PWM signal. As a result, a change in the operation mode of the power converter circuit is detected to allow the increase/decrease ratio of the coil current to correspond to a command switching ratio.
US07816896B2 Circuits and methods for controlling a converter
Circuits and methods for controlling a converter are disclosed. A first switch within the converter can be turned off, and a second switch within the converter alternately can be turned on and off in response to a switch control signal while the first switch is turned off. By turning the second switch alternately on and off, energy stored in the converter can be recovered to a power source of the converter.
US07816895B2 Power supplying device
A power supplying device includes: an output transformer including first and second output coils for generating first intermediate voltages from an input voltage; a voltage adjusting transformer including primary and secondary coils; a first rectifying-and-filtering circuit connected to the first output coil for generating a first output voltage from the first intermediate voltage obtained from the first output coil; the primary coil being connected in parallel to the first output coil, the secondary coil being connected in series to the second output coil and being coupled to the primary coil for generating a second intermediate voltage from the first intermediate voltage obtained from the first output coil; and a second rectifying-and-filtering circuit connected to the secondary coil for generating a second output voltage from a combined voltage combining the second intermediate voltage obtained from the secondary coil with the first intermediate voltage obtained from the second output coil.
US07816892B2 Battery charger for preventing charging currents from overshooting during mode transition and method thereof
A battery charger for charging a battery through controlling a charging regulation circuit is provided. The battery charger includes a constant voltage mode controller, a current sensing unit, and a reference voltage generator. The constant voltage mode controller is for comparing a battery voltage of the battery with a first reference voltage to generate a regulation signal, and utilizing the regulation signal to control the charging regulation circuit to regulate a charging current applied to the battery. The current sensing unit is for monitoring the charging current to generate an error signal. The reference voltage generator is for setting the first reference voltage according to the error signal. By adding a voltage generator to the battery charger, the overshoot charging current will be reduced and the mode transition will become smooth.
US07816890B2 Semiconductor unit for protecting secondary battery, battery pack having the semiconductor unit built-in and electronic apparatus using it
A semiconductor unit for protecting a secondary battery has a current detecting terminal converting a charging current to a negative voltage with respect to a negative electrode potential (ground potential) of the secondary battery when the secondary battery is charged, converting the charging current to a positive voltage with respect to the negative electrode potential (ground potential) of the secondary battery when the secondary battery is discharged, and detecting the charging/discharging current; and a test signal generating circuit generating a first test signal when the voltage of the current detecting terminal lowers to a first negative voltage which does not occur in a normal operation state of the semiconductor unit, and generating a second test signal when the voltage of the current detecting terminal lowers to a second negative voltage lower than the first negative voltage.
US07816889B2 Method of charging rechargeable battery and protection circuit for rechargeable battery
A method for charging a rechargeable battery, and a protection circuit for the rechargeable battery. The protection circuit perceives whether the battery is charged or not by sensing the voltage of the bare cell, changes the direct voltage applied between a gate electrode and a source electrode of a charging field effect transistor, which is connected in series between one terminal of the bare cell and one terminal of a charger, and controls the amount of the current flowing from the source electrode of the charging field effect transistor to a drain electrode at a low level, thereby maintaining a low charging rate of the battery.
US07816888B2 Battery pack lockable with a cordless power tool
A battery pack with a device for locking said battery pack to a cordless power tool has a guide configured to guide the battery pack in a predetermined movement direction as it moves between a locking position in which it is locked to the cordless power tool and a removal position in which it is removed from the cordless power tool, the guide has a break in at least one location between the locking position and removal position, and at said location a force acting on the battery pack moves the battery pack into a safety position offset from the guide, in which the battery pack is prevented from moving further along the guide into the removal position.
US07816887B2 Battery charger for portable equipment
The present invention relates to a battery charger for charging multiple types of portable equipments, comprising a charging pin housing including a plurality of charging spring pins having a predetermined distance therebetween; a moving motor for detecting an insertion of a battery and sliding the charging pin housing inward and outward; and a charge controller for suspending an operation of the moving motor when a contact of a charging terminal of the inserted battery to two or more charging spring pins of the plurality of the charging spring pins are detected during the sliding of the charging pin housing, and for quick-charging the battery through the two or more charging spring pins connected to a charging circuit. In accordance with the present invention, a discharged battery of a portable equipment may be charged easily regardless of a difference between sizes, polarities and positions of terminals of the battery of different portable equipments including mobile phones.
US07816882B2 Method of protecting an electronic device driven by DC motor and circuit for detecting positioning signals thereof
A method for protecting an electronic apparatus driven by a DC motor and a detection circuit for detecting positioning signals thereof. The electronic device includes an optical encoder, a code strip, and a DC motor. While moves along the code strip, the optical encoder outputs a first positioning signal and a second positioning signal for the control of the DC motor. The method includes the steps described below. First, states of the first and second positioning signals are detected. If the states of the first and second positioning signals are normal, the DC motor is controlled according to the first and second positioning signals. If the first positioning signal or the second positioning signal is abnormal, a preventive method is performed.
US07816877B2 Brake-controllable brushless motor
A brake-controllable brushless motor has a rotor and a stator having polyphase coils; a polar position detector whereby electric power is supplied to the coil selected by its phase in response to the polar positions of the rotor detected by the polar position detector; a driver division for controlling the electric supply to the coils; a motor pulse identifier for recognizing motor pulse signals fed from the polar position detector; and a delayed pulse generator for producing phase-delayed pulse signals in response to the pulse signals fed from the motor pulse identifier, thereby ensuring that when the brushless motor is braked, the phase delay of the delayed pulse signals is progressively and continuously enlarged, and that the coils receive a controlled electric supply from the driver division in response to the delayed pulse signals.
US07816876B2 Motor control device and motor drive system
Let an axis parallel to a magnetic flux produced by a permanent magnet provided on a rotor of a motor be called a d-axis, let an axis leading the d-axis by an electrical angle of 90 degrees be called a q-axis, and let control axes corresponding to the d-axis and the q-axis be called a γ-axis and a δ-axis, respectively. Then, a motor control device performs vector control of the motor with the γ-axis and the δ-axis made different from the d-axis and the q-axis, respectively, and with a motor current passing through the motor broken down into a γ-axis current on the γ-axis and a δ-axis current on the δ-axis. The motor control device has an estimator that estimates, as an estimated magnetic flux, a flux linkage of an armature winding of the motor, or estimates, as an estimated induction voltage, an induction voltage generated by the flux linkage and the rotation of the motor; and a specified current value deriving portion that derives, by using the estimated magnetic flux or the estimated induction voltage, a specified γ-axis current value to be followed by the γ-axis current.
US07816875B2 High torque gearless actuation at low speeds for swing gate, roll-up gate, slide gate, and vehicular barrier operators
The invention is a system for gearless operation of a movable barrier utilizing Lorentz forces, and in particular, a movable barrier operator retrofitted with a gearless motor capable of high torque at very low speeds. Eliminating a gear system in accordance with the present invention lowers maintenance requirements, increases efficiency, and streamlines operation of any movable barrier. By utilizing a motor which produces high-torque at low a speeds a system in accordance with the present invention does away with the need for complicated gears and pulley systems in order to achieve control of movable barriers. The present invention allows manufacturers, distributors and consumers to implement movable barrier systems with much more versatility and efficiency.
US07816870B2 Fast ferroelectric phase shift controller for accelerator cavities
A method and systems for fast ferroelectric tuning of RF power used in a particle accelerating system. By adjusting the voltages fed to the ferroelectric phase shift controller, the amplitude and phase of the RF power wave are altered, thus changing the coupling of the power generating circuit and the superconducting cavity. By altering this coupling rapidly, maximum power transfer efficiency can be achieved, which is important given the large amounts of power shunted through the particle accelerating system. In one embodiment, the ferroelectric tuner is optimally made of a magic-T waveguide circuit element and two phase shifters, although other implementations of the system may be utilized.
US07816868B2 Plasma display panel with magnesium oxide film having an oxygen deficiency
A variation with the passage of time of a response speed is reduced. In a plasma display panel having a magnesium oxide film formed on a dielectric layer covering electrodes for gas discharge, the magnesium oxide film has an oxygen deficiency amount within a range of 3.0×1017 to 1.0×1020 per cubic centimeter, preferably within a range of 3.0×1017 to 1.0×1018 per cubic centimeter. The magnesium oxide film has a crystal orientation of (220) plane orientation.
US07816866B2 Photocathode comprising a plurality of openings on an electron emission layer
A semiconductor photocathode 1 includes: a transparent substrate 11; a first electrode 13, formed on the transparent substrate 11 and enabling passage of light that has been transmitted through the transparent substrate 11; a window layer 14, formed on the first electrode 13 and formed of a semiconductor material with a thickness of no less than 10 nm and no more than 200 nm; a light absorbing layer 15, formed on the window layer 14, formed of a semiconductor material that is lattice matched to the window layer 14, is narrower in energy band gap than the window layer 14, and in which photoelectrons are excited in response to the incidence of light; an electron emission layer 16, formed on the light absorbing layer 15, formed of a semiconductor material that is lattice matched to the light absorbing layer 15, and emitting the photoelectrons excited in the light absorbing layer 15 to the exterior from a surface; and a second electrode 18, formed on the electron emission layer.
US07816864B2 Double-shielded electroluminescent panel
A double-shielded electroluminescent panel includes an electroluminescent device, an upper electrical shield and a lower electrical shield. The upper electrical shield is a transparent conductive material, and is overlaid on the illuminating surface of the electroluminescent device. The lower electrical shield is an electrical conductive material, and is mounted on the non-illuminating surface of the electroluminescent device. The upper electrical shield and lower electrical shield are together connected to the ground line of a power source. Therefore, the occurrence of electromagnetic interference and an electric shock is avoided.
US07816853B2 Laser stimulated cathode
A cathode has an emission layer that thermionically emits electrons upon exposure with a laser beam. The material of the emission layer has a product of density (ρ), measured in kg m 3 , heat capacity (Cp), measured in J kg ⁢ ⁢ K and heat conductivity (λ), measured in W mK that is, at room temperature, maximally 500,000 J 2 m 4 ⁢ K 2 ⁢ s . Such a cathode has an improved thermionic emission of electrons.
US07816852B2 Electron emission display device with anode terminal
An electron emission display includes first and second substrates facing each other to form a vacuum envelope, an electron emission unit formed on the first substrate, and a light emission unit formed on the second substrate. The light emission unit includes an anode electrode formed on the second substrate and electrically connected to at least one anode terminal to receive an anode voltage from the anode terminal, and the anode terminal is arranged on a side of the first substrate external to the vacuum envelope and in parallel to the first substrate.
US07816843B2 Light signaling device
Luminous signalling device (1) includes one or more light tubes (8) and focusing elements (2, 3, 4, 5, 6, 7) for focusing a light beam, these elements being capable of focusing a light beam coming from the light tube(s), the elements for focusing a light beam comprising several cylindrical lenses (2, 3, 4, 5, 6, 7), each cylindrical lens having a longitudinal axis lying parallel to a straight section (9, 10, 11) of the light tube. The straight sections (9, 10, 11) are oriented in several directions around a predetermined azimuthal axis (A), the number and the orientation of the straight sections being chosen so that the light beams coming from the straight sections and focused by the cylindrical lenses (2, 3, 4, 5, 6, 7) are directed in all azimuthal directions about the azimuthal axis.
US07816840B2 Spindle and flexible hinge used in ultrasonic machine
A spindle used in an ultrasonic machine for transmitting vibration to a working tool of the ultrasonic machine is disclosed. The spindle includes a main body, a rotor disposed in the main body, an elastic clamping unit disposed in the rotor, a vibrating unit having one end thereof connected to the inner wall of the rotor while the other end connected to the elastic clamping unit, and a pre-pressure unit penetrating the rotor and one end thereof connected to the elastic clamping unit to provide the elastic clamping unit with rigidity against the rotor, thereby making the elastic clamping unit provide pre-pressure to the vibrating unit which further provides the elastic clamping unit with vibration against the rotor. The present invention further provides a flexible hinge for the spindle.
US07816837B2 Surface acoustic wave sensor
A surface acoustic wave sensor for detecting a target substance by measuring the change in frequency due to the mass applied to a reaction membrane placed on a surface acoustic wave element having high sensitivity due to the improvement of the surface acoustic wave element structure. The surface acoustic wave sensor includes an SH-type surface acoustic wave and a rotated Y-cut LiTaO3 substrate having Euler angles (0°, 120° to 140°, 0°±5°); electrodes principally containing Au, for exciting a surface acoustic wave, the electrodes being arranged on the LiTaO3 substrate; and a reaction membrane bound to a target substance or a binding substance bound to the target substance covering the electrodes arranged on the LiTaO3 substrate. The interdigital transducers have a normalized thickness of about 3.0% to about 5.0%, the normalized thickness being determined by normalizing the thickness of the interdigital transducers by the wavelength of the surface acoustic wave.
US07816829B2 Dual motor
A dual motor has a shaft and a first motor connected to the shaft. The first motor is a standard electrical motor receiving voltage steps. The first motor provides a rotational force to the shaft when the voltage is applied. A second motor is also connected to the shaft, and the second motor is a permanent magnet motor comprising a flexible member connected to the shaft at a flexible member inside end. The permanent magnet motor also has an inside magnet mounted to a flexible member outside end, and the inside magnet moves relative to the shaft. The permanent magnet motor also has an outside housing. An outside magnet is mounted to the outside housing, and stepped voltage application flexes the flexible member. Optionally, stepped voltage application flexes the flexible member so that the outside magnet rotates relative to the inside magnet.
US07816828B2 Synchronous machine
A magnet wheel and a stator winding which are necessary for an excitation device are included in a synchronous machine. Energy is transferred to the magnet wheel through inductivity, preferably, energy to a super-conductive coil, by the excitation device. Protection against the magnetic field produced by the current in the winding head is provided in the form of a specific system which is used to reduce the corruptions of the interfering fields of stator and rotor winding.
US07816827B2 Brushless motor
A brushless motor is provided with: a tubular stator case; a stator core; a rotor rotatably supported via a bearing inside the stator core; a bracket which closes an opening at one end of the stator case; a coil bobbin around which a coil is wound is mounted on an inner peripheral surface of the stator core; a lead wire which feeds power to the coil; and a wiring substrate which relays a connection between one end of the lead wire and the coil, wherein: a drawn-out hole is formed on the bracket at the position corresponding to the connection point of said one end of the lead wire and the wiring substrate such that the other end of the lead wire is drawn outward; and a harness guide is provided on a peripheral edge of the drawn-out hole such that the drawn lead wire is bent and fixed.
US07816824B2 Electric motor with permanent magnet excitation and rotor cooling
The invention relates to an electric motor (1) with permanent magnet excitation, comprising a stator (2), a rotor (8), comprising a hollow shaft (13) on which the permanent magnets (9) are positioned. The hollow shaft (13) is sealed tight against an output shaft (7) at least at the end faces thereof and a suitable coolant is provided in the enclosed cavity (14) which, during operation of the electric motor, evaporates from the relatively hot hollow shaft in the region of the permanent magnets (9) and condenses in the region of the relatively cold output shaft (7) such as to introduce a radial and axial heat transport.
US07816821B2 Method for judging a status of varnish impregnation
A varnish impregnation state determination method for determining a varnish impregnation state of a core assembly that is formed by disposing a coil inside a slot of a motor core and impregnating the coil and an interior of the slot with a varnish, including applying an alternating current voltage between the motor core and the coil to determine tan δ that serves as a dielectric dissipation factor; and determining that the varnish impregnation state of the core assembly is normal when a value of the tan δ is equal to or smaller than a predetermined non-defective article reference value.
US07816818B2 Stove knob timer device
A stove knob timer device for use with a stove prompts a user to monitor a cooking event through a series of increasingly aggressive audible prompts. The timer device includes a main housing for engaging a stove operational shaft and which, when rotated to activate a respective stove burner, actuates a timer. After a predetermined time, a speaker is activated to emit an audible alarm to prompt a user to monitor the stove and to require a reset button to be pressed. If the reset button is not pressed in a predetermined time, the speaker is actuated to emit a more aggressive alarm so as to more urgently or even awaken a user. If the timer is reset, the original predetermined time is restarted. The timer device may include programming to adjust between timer modes and have structures enabling universal fit on various stove configurations.
US07816812B2 Electronic device, and system for DC voltage conversion
An electronic device includes: a first input terminal to which a first DC supply voltage of a fuel cell system having a controllable supply voltage is provided; a second input terminal to which a second DC supply voltage of a rechargeable secondary battery is provided; a DC voltage conversion circuit which receives the first and second DC supply voltages from the first and second input terminals, and supplies a current of a desired voltage to a load; a charging circuit which receives the first DC supply voltage from the first input terminal, and supplies a DC supply voltage for charging to the second input terminal; and a control circuit which determines a desired value of the first DC supply voltage in accordance with a value of the second DC supply voltage of the secondary battery, and provides the determined desired value to the fuel cell system.
US07816811B2 Portable power source to provide power to an electronic device via an interface
A portable power source is configured for use with an electronic device. The portable power source cooperates and communicates with the electronic device via a peripheral bus to which the electronic device is attachable. The portable power source includes circuitry to process a power request signal from the electronic device to determine whether a device connected to a bus interface of the portable power source is requesting power from the portable power source.
US07816805B2 Power supply system with multiphase motor and multiphase inverter
In a power supply system, a controller is electrically connected with a plurality of switching elements of a multiphase inverter. The controller switches the plurality of switching elements on and off during a multiphase motor being activated. This converts a voltage of a first power storage device into a multiphase AC voltage so as to supply the multiphase AC voltage to the multiphase motor. This also boosts a voltage of a second power storage device to charge the first power storage device by the boosted voltage via multiphase windings of the motor. The controller switches the plurality of switching elements on and off during the multiphase motor being inactivated to thereby boost the voltage of the second power storage device to charge the first power storage device by the boosted voltage.
US07816799B2 Method and device for energy generation
A method and device for using magnetostriction to generate electricity from fluid motion. The device includes a first structural component, an outer housing, and a strain structure. The outer housing substantially circumscribes the first structural component and at least partially defines an annular space between the first structural component and the outer housing. The strain structure is coupled within the annular space between the first structural component and the outer housing. The strain structure experiences a change in physical strain imposed by a bearing in response to a relative movement between the bearing and the strain structure. The strain structure includes a magnetostrictive material to generate a magnetic field in response to the change in the physical strain.
US07816796B2 Hand-held power tool and method for operating a heating device of a hand-held power tool
A hand-held power tool has a drive motor driving a tool and a generator. One or more heating devices having one or more heating elements are provided. The generator supplies the one or more heating devices with energy. A control device controls a power supplied to the one or more heating elements as a function of at least one operating parameter of the drive motor.
US07816791B2 Bonding pad for contacting a device
A bonding pad on a substrate has a first metal structure establishing an electrical connection between a device and a bonding area, and a second metal structure arranged at the bonding area. The first metal structure extends, within the bonding area, at least over part of the bonding area between the substrate and the second metal structure, so as to contact the second metal structure, the second metal structure being harder than the first metal structure.
US07816786B2 Semiconductor unit, and power conversion system and on-vehicle electrical system using the same
A semiconductor device includes a semiconductor chip and leads electrically connected to the electrodes of the semiconductor chip. A hollow radiator base houses the semiconductor device which is molded with high-thermal-conductivity resin having an electrical insulating property. The radiator base has a cooling-medium channel therein or radiating fins on the outside. Alternatively, the radiator base is housed in a second radiator base.
US07816784B2 Power quad flat no-lead semiconductor die packages with isolated heat sink for high-voltage, high-power applications, systems using the same, and methods of making the same
Disclosed are PQFN semiconductor die packages for high-voltage, high-power applications, systems using the packages, and methods of making the packages. An exemplary package comprises a leadframe, a semiconductor die disposed on the leadframe, and a heat sink member disposed on the semiconductor die and the leadframe and integrated into the molding material of the package. The heat sink member has an electrically insulating substrate with a high breakdown voltage, and one or more conductive layers disposed on a first surface of the substrate that electrically interconnect the semiconductor to one or more leads of the leadframe.
US07816783B2 Resin wiring substrate, and semiconductor device and laminated semiconductor device using the same
On a surface of a resin base material (11), a first resin coating film (19) having a larger thickness and a larger area than a second resin coating film (20) formed on the other surface of the resin base material (11) is continuously formed. The second resin coating film (20) is formed so as to be separated into a plurality of portions.
US07816776B2 Stacked semiconductor device and method of forming serial path thereof
A stacked semiconductor device and a method of forming a serial path of the stacked semiconductor device are provided. The stacked semiconductor device includes a plurality of chips each having a first internal circuit for receiving an input signal, performing a designated operation and outputting an output signal. Each of the chips includes a serial bump disposed at the same position on one surface of each of the chips, receiving the input signal and transferring the input signal to the first internal circuit, and a serial through-silicon via (TSV) disposed at a position symmetrical to the serial bump with respect to a center of the chip to penetrate the chip, and receiving and transferring the output signal. Here, the chips are alternately rotated and stacked, so that the serial TSV and the serial bumps of adjacent chips contact each other. According to the stacked semiconductor device and method, a plurality of chips having the same pattern are rotated about the center of the chips and stacked, so that a parallel path and a serial path can be formed.
US07816772B2 Methods and apparatus for multi-stage molding of integrated circuit package
Methods and apparatus for providing an integrated circuit using a multi-stage molding process to protect wirebonds. In one embodiment, a method includes attaching a die to a leadframe having a lead finger, attaching a wirebond between the die and the leadfinger, applying a first mold material over at least a portion of the wirebond and the die and the leadfinger to form an assembly, waiting for the first mold material to at least partially cure, and applying a second mold material over the assembly.
US07816770B2 Device and method for hermetically sealing a cavity in an electronic component
To hermetically seal a cavity in a microelectronic component, a cap located in a sealing device is positioned above the orifice opening into the cavity. The cap plastically deforms to seal the cavity. The sealing device includes a cavity permitting the cavity of the microelectronic component to be filled. The sealing device slides along the component so as to be positioned opposite either the filling cavity, or the cap.
US07816767B2 Negative differential resistance diode and SRAM utilizing such device
A negative differential resistance (NDR) diode and a memory cell incorporating that NDR diode are provided. The NDR diode comprises a p-type germanium region in contact with an n-type germanium region and forming a germanium pn junction diode. A first gate electrode overlies the p-type germanium region, is electrically coupled to the n-type germanium region, and is configured for coupling to a first electrical potential. A second gate electrode overlies the n-type germanium region and is configured for coupling to a second electrical potential. A third electrode is electrically coupled to the p-type germanium region and may be coupled to the second gate electrode. A small SRAM cell uses two such NDR diodes with a single pass transistor.
US07816766B2 Semiconductor device with compressive and tensile stresses
A semiconductor device includes a gate electrode formed on a silicon substrate in correspondence to a channel region via a gate insulation film, and source and drain regions of p-type formed in the silicon substrate at respective outer sides of sidewall insulation films on the gate electrode, a pair of SiGe mixed crystal regions formed in the silicon substrate at respective outer sides of the sidewall insulation films epitaxially to the silicon substrate so as to be enclosed respectively by the source and drain regions, each of the SiGe mixed crystal regions being grown to a level above a level of a gate insulation film interface between the gate insulation film and the silicon substrate, wherein there is provided a compressive stress film at respective top surfaces of the SiGe mixed crystal regions.
US07816762B2 On-chip decoupling capacitor structures
The present disclosure provides on-chip decoupling capacitor structures having trench capacitors integrated with planar capacitors to provide an improved overall capacitance density. In some embodiments, the structure includes at least one deep trench capacitor, at least one planar capacitor, and a metal layer interconnecting said deep trench and planar capacitors. In other embodiments, the structure includes at least one deep trench capacitor and a metal layer in electrical communication with the at least one deep trench capacitor. The at least one deep trench capacitor has a shallow trench isolation region, a doped region, an inner electrode, and a dielectric between the doped region and the inner electrode. The dielectric has an upper edge that terminates at a lower surface of the shallow trench isolation region.
US07816757B2 Semiconductor device including a digital semiconductor element and an analog semiconductor element in a common semiconductor device
High density mounting and power source sharing are achieved by a digital semiconductor element and an analog semiconductor element provided in a common semiconductor device. A power layer for analog operation is connected to one end of an EBG (Electromagnetic Band Gap) layer, a power layer for digital operation is connected to the other end of the EBG layer, ground terminals for the respective elements are connected to a common ground layer, and a ground layer for separating the power layer for analog operation and the EBG layer from each other is disposed between the power layer for analog operation and the EBG layer. Thereby, high density mounting is achieved along with reducing interference of the power source to an analog chip.
US07816751B2 Optical sensor
An optical sensor includes a silicon-rich dielectric photosensitive device and a read-out device. The silicon-rich dielectric photosensitive device includes a first electrode, a second electrode, and a photosensitive silicon-rich dielectric layer disposed therebetween. The photosensitive silicon-rich dielectric layer includes a plurality of nanocrystalline silicon crystals therein. The read-out device is electrically connected to the first electrode of the silicon-rich dielectric photosensitive device for reading out opto-electronic signals transmitted from the photo-sensitive silicon-rich dielectric layer.
US07816749B2 Photoelectric conversion device and method of producing the same, and method of producing line image sensor IC
A plurality of line image sensor ICs 110 are formed to be arranged in X, Y directions with gaps therebetween on a semiconductor substrate 101. The gaps between the line image sensor ICs 110 become scribe lines 102X, 102Y. A pattern of dummy interconnects 120 is formed in a region where a short side 110S of an arbitrary line image sensor IC 110 is opposed to a short side 110S of another line image sensor IC 110 adjacent to the arbitrary line image sensor IC 110 in the X direction in a region where the scribe line 102Y is formed. When a material gas is generated by plasma CVD, the material gas is uniformly deposited not only on the line image sensor ICs 110, but also on the dummy interconnects 120. Consequently, a protective film with a uniform thickness can be formed on the line image sensor ICs 110.
US07816748B2 Semiconductor device and method for manufacturing same
The absorption of moisture from a wall surface of an apertured part formed in an interlayer insulating film in accordance with a light-receiving part of a light detector is minimized and deterioration of wiring in the interlayer insulating film is prevented. A position that corresponds to a light-receiving part 52 of a wiring-structure layer 90 obtained by layering an Al layer and an interlayer insulating film composed of SOG or another material is etched, and an apertured part 120 is formed. A silicon nitride film 130 is then deposited on a side-wall surface and bottom surface of the apertured part 120 via CVD. The silicon nitride layer 130 prevents moisture from infiltrating the wiring-structure layer 90.
US07816746B2 Spin-tunnel transistor and magnetic reproducing head
A spin-tunnel transistor having a tunnel barrier layer formed of an antiferromagnetic material which is exchange coupled with a first or second ferromagnetic metal layer of a base B formed adjoining to the antiferromagnetic material, so as to fix magnetization of the adjoining ferromagnetic layer. The base B includes a nonmagnetic metal layer which is formed between the first and second ferromagnetic metal layers and decouple magnetization coupling between the first and second ferromagnetic metal layers. The base B is formed between a collector and an emitter to form tri-terminal device. Those spin-tunnel transistor may be used as a sensor of a magnetic reproducing head used in a hard disk drive.
US07816744B2 Gate electrodes of HVMOS devices having non-uniform doping concentrations
A semiconductor structure includes a semiconductor substrate; a first high-voltage well (HVW) region of a first conductivity type overlying the semiconductor substrate; a second well region of a second conductivity type opposite the first conductivity type overlying the semiconductor substrate and laterally adjoining the first well region; a gate dielectric extending from over the first well region to over the second well region; a drain region in the second well region; a source region on an opposite side of the gate dielectric than the drain region; and a gate electrode on the gate dielectric. The gate electrode includes a first portion directly over the second well region, and a second portion directly over the first well region. The first portion has a first impurity concentration lower than a second impurity concentration of the second portion.
US07816740B2 Memory cell layout structure with outer bitline
An integrated circuit (IC) includes a memory cell having source/drain regions for defining source/drains of a first pull-up or pull-down (PU/PD) transistor for a first storage node, a second PU/PD transistor for a second storage node, and driver, cell pass, and buffer pass transistors. The memory cell includes a first gate electrode region for the first PU/PD and driver transistors, a second gate electrode region for the cell pass and buffer pass transistors, and a third gate electrode region for the second PU/PD transistor. The third gate electrode region and the cell pass transistor are coupled to the first storage node and the first gate electrode region is coupled to the second storage node. The buffer pass and driver transistors are coupled to a source/drain path of the cell pass transistor and the buffer pass transistor is coupled between a bitline (BL) node and the driver transistor.
US07816732B2 Integrated trench MOSFET and Schottky rectifier with trench contact structure
A trench MOSFET in parallel with trench Schottky barrier rectifier is formed on a single substrate. The present invention solves the constrains brought by planar contact of Schottky, for example, the large area occupied by planar structure. As the size of present device is getting smaller and smaller, the trench Schottky structure of this invention is able to be shrink and, at the same time, to achieve low specific on-resistance. By applying a double epitaxial layer in trench Schottky barrier rectifier, the device performance is enhanced for lower Vf and lower reverse leakage current Ir is achieved.
US07816730B2 Semiconductor device and method for fabricating the same
A semiconductor device comprises a fin-type active region defined by a semiconductor substrate having a device isolation structure, a recess formed over the fin-type active region, and a gate electrode including a silicon germanium (Si1-xGex) layer for fill the recess (where 0
US07816729B2 Trenched MOSFET device with trenched contacts
A trenched semiconductor power device that includes a trenched gate disposed in an extended continuous trench surrounding a plurality of transistor cells in an active cell area and extending as trench-gate fingers to intersect with a trenched gate under the gate metal runner at a termination area. At least one of the trench-gate fingers intersects with the trenched gate under the gate metal runner near the termination area having trench intersection regions vulnerable to have a polysilicon void and seam developed therein. At least a gate contact trench opened through an insulation layer covering the semiconductor power device wherein the gate contact trench penetrating from the insulation layer and extending into the gate polysilicon and the gate contact trench is opened in an area away from the trench intersection regions and also away from a center portion of said the trenched gate underneath said gate runner metal where a polysilicon void or a seam is likely formed thus avoid the formation of the vulnerable spots.
US07816717B2 Semiconductor memory device
A semiconductor memory device, comprising: a semiconductor substrate; a memory cell section comprising a memory transistor provided on the semiconductor substrate, the memory transistor including a first gate electrode provided on the semiconductor substrate with a gate insulating film interposed therebetween, and a source and drain provided at both sides of the first gate electrode on the semiconductor substrate, and a ferroelectric capacitor provided above the memory transistor, the ferroelectric capacitor including a first electrode film connected to any one of a source and drain of the memory transistor, a second electrode film connected to the other one of the drain and source of the memory transistor, and a ferroelectric film provided between the first electrode film and the second electrode film, the memory cell section having the memory transistor and the ferroelectric capacitor connected in parallel to each other; and a select transistor section, comprising a select transistor provided at an end of the memory cell section, the select transistor including a second gate electrode provided on the semiconductor substrate with the gate insulating film interposed therebetween, and a source and drain provided at both sides of the second gate electrode on the semiconductor substrate, and a third electrode film connected to the source and drain of the select transistor and connected to a bit line via a bit line contact.
US07816707B2 Field-effect transistor with nitride semiconductor and method for fabricating the same
An AlN buffer layer, an undoped GaN layer, an undoped AlGaN layer, a p-type GaN layer and a heavily doped p-type GaN layer are formed in this order. A gate electrode forms an Ohmic contact with the heavily doped p-type GaN layer. A source electrode and a drain electrode are provided on the undoped AlGaN layer. A pn junction is formed in a gate region by a two dimensional electron gas generated at an interface between the undoped AlGaN layer and the undoped GaN layer and the p-type GaN layer, so that a gate voltage can be increased.
US07816706B2 Power semiconductor device
The power semiconductor device with a four-layer npnp structure can be turned-off via a gate electrode. The first base layer comprises a cathode base region adjacent to the cathode region and a gate base region adjacent to the gate electrode, but disposed at a distance from the cathode region. The gate base region has the same nominal doping density as the cathode base region in at least one first depth, the first depth being given as a perpendicular distance from the side of the cathode region, which is opposite the cathode metallization. The gate base region has a higher doping density than the cathode base region and/or the gate base region has a greater depth than the cathode base region in order to modulate the field in blocking state and to defocus generated holes from the cathode when driven into dynamic avalanche.
US07816705B2 Method of fabricating vertical structure LEDs
A method of fabricating semiconductor devices, such as GaN LEDs, on insulating substrates, such as sapphire. Semiconductor layers are produced on the insulating substrate using normal semiconductor processing techniques. Trenches that define the boundaries of the individual devices are then formed through the semiconductor layers and into the insulating substrate, beneficially by using inductive coupled plasma reactive ion etching. The trenches are then filled with an easily removed layer. A metal support structure is then formed on the semiconductor layers (such as by plating or by deposition) and the insulating substrate is removed. Electrical contacts, a passivation layer, and metallic pads are then added to the individual devices, and the individual devices are then diced out.
US07816694B2 Light emitting semiconductor device
A light emitting semiconductor device is provided, wherein the light emitting semiconductor device comprises a substrate, a plurality of flip chips, a heat conductive board and an insulating board. These flip chips are electrically connected on the substrate. The heat conductive board has a protruding portion used to support the substrate. The insulating board has a plurality of connecting pads and an opening, wherein the protruding portion is sheathed in the opening, so as to expose the substrate. The exposed substrate is then electrically connected to the connecting pads.
US07816690B2 Light-emitting device
A light-emitting device includes a light-emitting element 12 and a wiring substrate 11 having a substrate body 17 having a protruding portion 25 at a position where the light-emitting device 12 is disposed and wiring patterns 21 and 22 disposed on the substrate body 17 and electrically connected to the light-emitting element 12.
US07816688B2 Semiconductor device and production method therefor
An upper part of a SIC substrate 1 is oxidized at a temperature of 800 to 1400° C., inclusive, in an oxygen atmosphere at 1.4×102 Pa or less, thereby forming a first insulating film 2 which is a thermal oxide film of 20 nm or less in thickness. Thereafter, annealing is performed, and then a first cap layer 3, which is a nitride film of about 5 nm in thickness, is formed thereon by CVD. A second insulating film 4, which is an oxide film of about 130 nm in thickness, is deposited thereon by CVD. A second cap layer 5, which is a nitride film of about 10 nm in thickness, is formed thereon. In this manner, a gate insulating film 6 made of the first insulating film 2 through the second cap layer 5 is formed, thus obtaining a low-loss highly-reliable semiconductor device.
US07816685B2 Integrated circuit device and method for manufacturing integrated circuit device
An object of the present invention is to provide a structure of a thin film circuit portion and a method for manufacturing a thin film circuit portion by which an electrode for connecting to an external portion can be easily formed under a thin film circuit. A stacked body including a first insulating film, a thin film circuit formed over one surface of the first insulating film, a second insulating film formed over the thin film circuit, an electrode formed over the second insulating film, and a resin film formed over the electrode, is formed. A conductive film is formed adjacent to the other surface of the first insulating film of the stacked body to be overlapped with the electrode. The conductive film is irradiated with a laser.
US07816684B2 Light emitting display device and method of fabricating the same
A light emitting display device includes a light emitting diode and a thin film transistor on a substrate, the light emitting diode and thin film transistor being electrically coupled to each other, and a photo diode on the substrate, the photo diode including an intrinsic region and a P-type doping region coupled to each other.
US07816683B2 Array substrate and display apparatus having the same
In an array substrate and a display apparatus, a gate line receives a gate pulse during a present 1H period and a data line receives a pixel voltage having a polarity inverted at every frame. When a thin film transistor is turned on in response to the gate pulse during the present 1H period, a pixel electrode receives the pixel voltage through the thin film transistor during the present 1H period. A pre-charging part pre-charges the pixel electrode to a common voltage that is a reference voltage of the pixel voltage in response to a previous gate pulse during a previous 1H period.
US07816680B2 Oxide semiconductors and thin film transistors comprising the same
Provided are oxide semiconductors and thin film transistors of the same. An oxide semiconductor includes Zn, In and Hf. The amount of Hf is in the range of about 2-16 at %, inclusive, based on the total amount of Zn, In, and Hf. A thin film transistor includes a gate and a gate insulating layer arranged on the gate. A channel corresponding to the gate is formed on the gate insulating layer. The channel includes an oxide semiconductor. The semiconductor oxide includes Zn, In and Hf. The amount of Hf is in the range of about 2-16 at %, inclusive, based on the total amount of Zn, In, and Hf. A source and a drain contact respective sides of the channel.
US07816671B2 Organic thin film transistor comprising phosphate-based self-assembled monolayer and method of manufacturing the same
Disclosed is an organic thin film transistor including a phosphate-based self-assembled monolayer and a method of manufacturing the same. Example embodiments relate to an organic thin film transistor, which may include a single bond type phosphate-based self-assembled monolayer without intermolecular cross-linking, between source/drain electrodes and an organic semiconductor layer, thus exhibiting improved electrical properties, e.g., increased charge mobility, and to a method of manufacturing the organic thin film transistor.
US07816655B1 Reflective electron patterning device and method of using same
One embodiment disclosed relates to a reflective electron patterning device. The device includes a pattern on a surface. There is an electron reflective portion of the pattern and an electron non-reflective portion of the pattern. Another embodiment disclosed relates to a method of reflecting a pattern of electrons. An electron beam is generated to be incident upon a surface. The pattern is formed on the surface. The incident electrons are reflected from a reflective portion of the pattern are prevented from being reflected from a non-reflective portion of the pattern.
US07816654B2 Single wavelength stimulated emission depletion microscopy
In apparatus for superresolution microscopy or microlithography, wherein a spot in the specimen to be examined or in the microlithographic medium is raised to an excited state by a first pulse of light, and a second pulse of light reduces the excitation in the peripheral parts of the spot to increase the resolution of the instrument, a method whereby the wavelength of the second pulse in the specimen or medium is the same as the wavelength of the first pulse, thereby allowing the cost and complexity of the apparatus to be lowered.
US07816648B2 Electron interferometer or electron microscope
In an electron beam interference system using an electron biprism, which is capable of independently controlling each of the interference fringe spacing s and the interference width W, both of which are important parameters for an interferometer and for an interferogram acquired by the interferometer, an optical system used in a two-stage electron biprism interferometer is adopted. The optical system uses two stages of electron biprisms in an optical axis direction to give the flexibility to the relative magnification relative to a specimen image and that relative to an image of a filament electrode of the electron biprism. In addition, as a two-stage configuration in which two objective lenses (51, 52) are combined, independently controlling the focal length of each objective lens makes it possible to set the relative magnification relative to a specimen image and that relative to an image of the filament electrode of the electron biprism at arbitrary values.
US07816646B1 Laser desorption ion source
Atmospheric pressure, intermediate pressure and vacuum laser desorption ionization methods and ion sources are configured to increase ionization efficiency and the efficiency of transmitting ions to a mass to charge analyzer or ion mobility analyzer. An electric field is applied in the region of a sample target to accumulate ions generated from a local ion source on a solid or liquid phase sample prior to applying a laser desorption pulse. The electric field is changed just prior to or during the desorption laser pulse to promote the desorption of charged species and improve the ionization efficiency of desorbed sample species. After a delay, the electric field may be further changed to optimize focusing and transmission of ions into a mass spectrometer or ion mobility analyzer. Charged species may also be added to the region of the laser desorbed sample plume to promote ion-molecule reactions between the added ions and desorbed neutral sample species, increasing desorbed sample ionization efficiency and/or creating desired product ion species. The cycling of electric field changes is repeated in a timed sequence with one or more desorption laser pulse occurring per electric field change cycle. Embodiments of the invention comprise atmospheric pressure, intermediate pressure and vacuum pressure laser desorption ionization source methods and devices for increasing the analytical flexibility and improving the sensitivity of mass spectrometric analysis.
US07816644B2 Photoactivated collision induced dissociation (PACID) (apparatus and method)
The invention provides a system apparatus and methods for fragmenting various molecules. In particular, the invention may be employed for fragmenting biomolecules like peptides to determine sequence information. The invention provides a mass spectrometry system for photo-activated collision induced dissociation. The mass spectrometry system or device includes an ion source for producing ions, a photon source adjacent to the ion source for photo-activating ions produced by the ion source, an electrical element adjacent to the photon source for creating an electric field for accelerating ions produced by the ion source and photo-activated by the photon source; wherein ions are produced by the ion source, photo-activated by the photon source and accelerated into a surface to cause dissociation of the activated ions; and a detector downstream from the ion source for detecting the collision induced and dissociated ions.
US07816643B2 Neutral atom trapping device
A neutral atom trapping device with a multipole-magnetic field-generating electrode is provided with a main current electrode through which main current flows, and a pair of sub-current electrodes through which sub-current flows, and which is located in parallel to and both sides of said main current electrode; a neutral atom trapping device with an S-shaped multipole-magnetic field-generating electrode.
US07816639B2 Machine for inspecting glass containers at an inspection station using an addition of a plurality of illuminations of reflected light
A machine for inspecting glass containers which are being rotated at an inspection station. A light source illuminates a selected area on a rotating glass container while the container rotates through a selected angle and a camera is triggered to capture an image while the bottle rotates through that angle. A plurality of sequential images are recorded and a critical addition is made to be inspected.
US07816635B2 Air vehicle wing pivot
A stowable wing structure incorporates a wing having a span equal to a fuselage length and movable from a stowed position longitudinally aligned with the fuselage to a deployed position perpendicular to the fuselage. A pivot offset laterally from a centerline of the fuselage and aft from a symmetry point on the centerline with a corresponding offset forward toward the leading edge from a chord centerpoint on the wing allows rotation of the wing from the stowed position to the deployed position with the rotation resulting in an aft position of the chord center point relative to the fuselage symmetry point.
US07816634B1 Barbeque assembly
A cooking utensil has a first member connected to a second member in a generally transverse configuration. The first member has a first end and a second end. The first end of the first member has a turner element used for turning food products. The second member has a first end and a second end. The first end of the second member has a fork element thereon. The second end of the second member has a brush assembly thereon used for applying sauces and condiments to food products. A cooperative structure is associated with the first member and the second member to connect the members in the generally transverse configuration.
US07816633B2 Method and apparatus for microwave assisted high throughput high pressure chemical synthesis
A method and associated instrument are disclosed for increasing the sequential rate at which a series of microwave assisted chemical reactions that potentially generate high pressure can be carried out. The method includes the steps of opening a pressure-resistant valve on a microwave-transparent pressure-resistant vessel to define a unpressurized pathway through the valve into the vessel, inserting a tube through the pathway in the valve and into the vessel, transferring at least one composition into the vessel through the tube, removing the tube from the vessel and from the pathway in the valve, closing the valve to seal the vessel against pressure release, and exposing the vessel and its contents to microwave radiation. The instrument includes a source of microwave radiation, a cavity in microwave communication with the source, an attenuator that forms at least a portion of the cavity, a pressure-resistant microwave-transparent reaction vessel having portions in the cavity and portions in the attenuator, a pressure-resistant valve on the mouth of the vessel, a reciprocating tube for passing through the valve and into the vessel when the valve is open, and means for mechanically inserting and retracting the tube through the valve and into the vessel when the vessel is in the cavity and the attenuator.
US07816632B2 Inductively heated clothing
Induction heatable clothing items such as footwear (22) and apparel (160) are provided which include a clothing body having an induction heatable element (36, 108, 112, 114, 116) and preferably having heat retentive material containing phase change material, wherein the element (36, 108, 112, 114, 116) is operable to be heated when subjected to an alternating magnetic field. The clothing items (22, 160) are heated using induction heaters (26, 84). In preferred forms, wireless temperature sensing is used to control heating of the items (22, 160). To this end, the heating elements (36, 108, 112, 114, 116) may be provided with RFID tag/temperature sensor assemblies (58, 60, 110), and the induction heaters (26, 84) are equipped with correlated RFID reader/writer devices (80). Alternately, microwire temperature sensors (120) may be used with the induction heaters (26, 84) having microwire detectors. In other embodiments, temperature monitoring is achieved using impedance detection feedback control.
US07816631B2 Inverter with a housing having a cooling unit
The inverter housing (1) has a cooling unit (2) for cooling the electronic and/or electric components (4, 5, 5a) of the inverter. The housing (1) of the inverter comprises at least two chambers, the two chambers (7, 8) being separated by a wall (6) for receiving the electronic and/or electric components (4, 5, 5a), the components (5) comprise cooling bodies (4) located on the one side of the wall in the one chamber (7) with the cooling bodies (4) being located on the other side of the wall (6) in the other chamber (5) and the electric or electronic component to be cooled have a high protection grade, the component (5a) being located in the other chamber (8), preferably on the wall side of the wall (6) of the other chamber (8), the other chamber (8) comprising the cooling unit (2).
US07816627B2 Attachment system for attaching an electric cable to a glass pane to provide electricity thereto
An attachment system for attaching an electric cable to a window pane. The system includes a generally elongated plate having a width approximately equal to a thickness of said pane, the plate being provided with a plurality of holes. A socket is fastened to the plate and is shaped and sized to receive a portion of the electric cable within it, the socket being in communication with an opening provided in the plate in order to permit electrical conductors to pass through the plate. The electric cable is fastened to the plate and the plate is fastened to an edge of the pane, in order to resist a 35 lb traction.
US07816624B2 Device for stripping outer covering of cable
A device (100) for stripping an outer covering (141) of a cable (140) includes a base (110) having a shaft (111) coupled thereto, a laser generator (130) configured for emitting a laser beam and a rotating arm (120). The shaft defines a central axis configured for coaxial alignment with the cable. The laser generator is arranged at rest relative to the rotating arm. The rotating arm includes at least one light directing member configured for directing the laser beam emitted from the laser generator to impinge upon a circumference of the outer covering of the cable. The rotating arm is rotatable relative to the central axis associated with the shaft in a manner such that the circumference of the outer covering of the cable can be impinged upon by the laser beam thus stripping the outer covering of the cable.
US07816617B2 Configurable intelligent conveyor system and method
A method includes deducting selected ones of a plurality of products from a first sorting and/or sequencing system to a conveying system, and determining data including at least one of: a predicted position of each of the selected ones of the plurality of products within the conveying system, and speed and direction of conveyors of the conveying system. The method also includes controlling movement of the selected ones of the plurality of products through the conveying system by controlling speed and direction of the conveyors based upon the determined data, and inducting the selected ones of the plurality of products onto a second sorting and/or sequencing system.
US07816614B2 Switch using elastic sheet
A sheet switch includes an elastic sheet (4) and a circuit board (5). The elastic sheet has a first sheet (10) having a metal sheet (11) plated on an upper surface thereof, a bending portion (12) bent toward the circuit board from a lateral extension thereof and a tail portion (121) extending backwardly from the bending portion for connecting with the circuit board. The elastic sheet further has a plurality of moveable contacts (20) attached to a lower surface of the first sheet, wherein the bending portion of the first sheet having a conductive component (14) affixed thereon.
US07816613B2 Arrangement for weighing transport vehicle load
A method for weighing a payload of a transport vehicle, a transport vehicle and a bogie structure. Vertical loads exerted on wheel suspension of the transport vehicle are measured with sensors and the measurement data is conveyed to a calculating unit of weighing. Further, on a side surface of a horizontal arm belonging to the bogie structure there is arranged a sensor for measuring the vertical load exerted on the horizontal arm.
US07816612B2 Rotary measuring device
A rotary measuring device includes a measuring unit, a centrifugal force error calculation block, and a weight value calculation block. The measuring unit includes a measuring plate and a load cell. The load cell has a fixed end and a free end on which the measuring plate is disposed. The centrifugal force error calculation block calculates, on the basis of a first measured value outputted from the load cell in a state where the measuring unit is rotating, an angular displacement θ with respect to a horizontal plane of the load cell in the vicinity of the free end. The weight value calculation block calculates a weight value of the object on the basis of the angular displacement value and a second measured value outputted from the load cell in a state where the measuring plate is receiving the load resulting from the object.
US07816611B2 Circuit board
After disposing metallic foils on either surface of a prepreg sheet of low compressibility having conducting holes filled with conductive paste, the prepreg sheet is compressed in a state of being kept at a relatively low temperature, and after that, the temperature is raised under pressure to melt and harden the resin in the prepreg sheet, and thereby, the connecting resistance is stabilized, and a high-quality circuit board can be obtained.
US07816610B2 Layout circuit
The layout circuit comprises a first 3×2 grid array and a second 3×2 grid array. The first 3×2 grid array comprises first, second and third signal contact points and the first and second fixed potential contact points are coupled to a first fixed potential. The first and second fixed potential contact points are arranged diagonally into the first 2×2 array and the first and second signal contact points are also arranged diagonally into the first 2×2 array. The second 3×2 grid array comprises fourth, fifth and sixth signal contact points and the third and fourth fixed potential contact points are coupled to the first fixed potential. The third and fourth fixed potential contact points are arranged diagonally into the second 2×2 array and the fourth and fifth signal contact points are also arranged diagonally into the second 2×2 array.
US07816602B2 Fiber distribution hub with outside accessible grounding terminals
The present disclosure relates to a telecommunications distribution hub having a cabinet that defines a primary compartment. The cabinet also includes one or more main doors for accessing the primary compartment. Telecommunications equipment is mounted within the primary compartment. The distribution hub further includes a secondary compartment that can be accessed from an exterior of the cabinet without accessing the primary compartment. A grounding interface is accessible from within the secondary compartment.
US07816601B2 Device and method for converting thermal energy into electrical energy
A device and method for using a field-responsive material that changes temperature when subjected to a respective field in combination with a thermal to electrical energy converter to accomplish the generation of electrical energy. The field-responsive material, such as an electrocaloric or magnetocaloric material, changes temperature when subjected to a change in a respective electric or magnetic field. The changing field applied to the field-responsive material causes a temperature change in the field-responsive material to heat or cool the field-responsive material. A thermal to electrical energy converter is in thermal contact with the field-responsive material, such that temperature changes in the field-responsive material in turn changes the temperature of the thermal to electrical energy converter, which the converter then converts into electrical energy. In this manner, the application of an appropriate electric or magnetic field can be utilized to generate thermal energy changes that can be converted into electrical energy.
US07816598B2 Electronic keyboard musical instrument having key actuators
An electronic keyboard musical instrument comprises a keyboard assembly including juxtaposed keys and juxtaposed swing weight mechanisms, each of the keys correspondingly linked with each of the swing weight mechanisms. Actuating members are provided corresponding to the respective swing weight mechanisms each of which in turn actuates each corresponding key. The actuating members are arranged in the vicinity of the fulcrum of the swing weight mechanisms and disposed in two rows as a front row and a rear row and extending downward through the key bed. The heights of the actuating members are made small. An actuator cover has a rearward descending slant wall so that the knees of the player will not be obstructed in depressing the pedals.
US07816597B2 Drum pad and manufacturing method thereof
A drum pad has a knitted material that is strechable and has a top surface to be beaten by a stick and a rear surface opposite to the top surface, a resin member that is strechable and thinner than the knitted material and that is capable of being thermally fused and bonded to the knitted material, and a rubber. The drum pad is formed of a first layer portion, a second layer portion, and a body portion. The first layer portion is formed in a region of the knitted material including the top surface thereof but not including the rear surface. The body portion is formed of the rubber. The second layer portion is formed in a remaining region of the knitted material other than the first layer portion and formed between the body portion and the first layer portion.
US07816596B2 Cajon with freely vibrating corners
A cajón includes a housing with sides forming at least one strike plate. One or several corners of a strike plate protrude beyond a recess of the housing for producing additional sound effects, such as rim-shots and rim-clicks.
US07816593B2 Musical instrument sound maximizer
Embodiments of the present invention are directed to deriving a useful life value of a vibrating member in a musical instrument by analyzing a spectral response to sound produced by the vibrating member.
US07816592B2 Stringed instrument string action adjustment
A stringed musical instrument comprises: a headstock with tuners; a neck having a fingerboard, and a neck extension; a body having a top, a back, a longitudinal recess in the back for receipt of the neck extension and a bridge with a saddle secured to the body; and, one or more strings stretched from the headstock over the neck and fingerboard and over a portion of the top of the body to contact points on the bridge saddle. The instrument is further provided with a pivotal mount for mounting the neck to the body and a string action adjustment member for moving the neck lower extended end within the body longitudinal recess and thereby the position of the neck relative to the body, whereby the height of the strings are adjusted relative to the neck and its fingerboard.
US07816591B1 Plants and seeds of hybrid corn variety CH339402
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH339402. The invention thus relates to the plants, seeds and tissue cultures of the variety CH339402, and to methods for producing a corn plant produced by crossing a corn plant of variety CH339402 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH339402.
US07816590B1 Plants and seeds of corn variety CV338423
According to the invention, there is provided seed and plants of the corn variety designated CV338423. The invention thus relates to the plants, seeds and tissue cultures of the variety CV338423, and to methods for producing a corn plant produced by crossing a corn plant of variety CV338423 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV338423 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV338423.
US07816581B2 Recombinant DNA constructs and methods for controlling gene expression
The present invention provides molecular constructs and methods for use thereof, including constructs including heterologous miRNA recognition sites, constructs for gene suppression including a gene suppression element embedded within an intron flanked on one or on both sides by non-protein-coding sequence, constructs containing engineered miRNA or miRNA precursors, and constructs for suppression of production of mature microRNA in a cell. Also provided are transgenic plant cells, plants, and seeds containing such constructs, and methods for their use. The invention further provides transgenic plant cells, plants, and seeds containing recombinant DNA for the ligand-controlled expression of a target sequence, which may be endogenous or exogenous. Also disclosed are novel miRNAs and miRNA precursors from crop plants including maize and soy.
US07816578B2 Transgenic transchromosomal rodents for making human antibodies
The present invention provides novel transgenic nonhuman mammals capable of producing human sequence antibodies, as well as methods of producing and using these antibodies.
US07816575B2 Removal of catalyst fines from a reaction system
This invention provides a process for limiting the loss of catalyst particles through olefin product streams and regenerator flue gas streams exiting the reaction system. In particular, this invention provides for removing catalyst particles from the reactor using a water stream and from the regenerator using a two step separation process. The two step process involves the use of a catalyst fine separation unit.
US07816574B2 Alkylaromatic production process
The present disclosure provides a process for selectively producing a desired monoalkylated aromatic compound comprising the step of contacting in a reaction zone an alkylatable aromatic compound with an alkylating agent in the presence of catalyst comprising a porous crystalline material under at least partial liquid phase conditions, said catalyst manufactured from extrudate to comprise catalytic particulate material of from about 125 microns to about 790 microns in size, having an Effectiveness Factor increased from about 25% to about 750% from that of the original extrudate, and having an external surface area to volume ratio of greater than about 79 cm−1.
US07816573B2 Molecular sieve composition
The invention relates to a process for converting hydrocarbons with a catalyst comprising a crystalline molecular sieve composition which is obtainable by crystallizing a pre-formed extrudate mixture in a reactor and, during crystallization, removing excess alkali metal hydroxide from the pre-formed extrudate. The pre-formed extrudate mixture comprises at least one source of ions of tetravalent element Y, at least one source of alkali metal hydroxide, water, optionally at least one seed crystal, and optionally at least one source of ions of trivalent element X. The reaction mixture has the following mole composition: Y:X2=10 to infinity; OH−:Y=0.001 to 2; and M+:Y=0.001 to 2; wherein M is an alkali metal. The amount of water in the mixture is at least sufficient to permit extrusion of said reaction mixture.
US07816569B2 Process for the preparation of chloromethane using recycled hydrogen chloride
The invention relates to a process for the preparation of chloromethane from methanol and hydrogen chloride contaminated with Si compounds, the Si compounds being methylchlorosilanes, methoxymethylsilanes and hydrolysis and condensation products thereof, in which some of the Si compounds are removed by condensation from the chloromethane formed and remaining Si compounds are washed out with methanol, the methanol thus obtained and containing Si compounds being used for the further preparation of chloromethane with hydrogen chloride.
US07816568B2 Direct catalytic conversion of cellulose materials to ethanol
Catalytic reactions conducted during acid digestion of cellulose materials, including paper, a wide range of grasses including prairie grass, switch grass, pine wood sawdust, bagasse dried after sugar cane processing, cotton, waste cellulose products and starch materials, are taught for direct conversion to ethanol. The cellulose material is thoroughly wet in concentrated sulfuric acid in the presence of transition metal complexes possessing a degree of symmetry. Ethanol formed during the reaction can be removed by distillation affording a continuous process.
US07816567B2 Method of producing lower alcohols from glycerol
A reactive-separation process converts glycerin into lower alcohols, having boiling points less than 200° C., at high yields. Conversion of natural glycerin to propylene glycol through an acetol intermediate is achieved at temperatures from 150° to 250° C. at a pressure ranging from 1 and 25 bar. The preferred applications of the propylene glycol are as an antifreeze, deicing compound, or anti-icing compound. The preferred catalyst for this process in a copper-chromium powder.
US07816563B1 Method for preparing hypocrellin
Improved methods of preparing hypocrellin B from 4,9-dihydroxy-3,10-perylenequinones are described.
US07816558B2 Triarylcarboxylic acid derivative
Provided is a triarylcarboxylic acid derivative, or an isomer, a prodrug, a hydrate, a solvate, a polymorph, or a pharmaceutically acceptable salt thereof, represented by the following general formula (I): wherein A is an optionally substituted aryl or heteroaryl, and B is an optionally substituted monocyclic heteroaryl; and a pharmaceutical composition comprising the same and a pharmaceutically acceptable carrier. The triarylcarboxylic acid derivative (I) exhibits potent xanthine oxidase inhibiting action and is therefore useful as a therapeutic agent for preventing or treating hyperuricemia, gout, inflammatory bowel disease, diabetic nephropathy and diabetic retinopathy.
US07816550B2 Processes for the production of organometallic compounds
This invention relates to processes for the production of organometallic compounds represented by the formula M(L)3 wherein M is a Group VIII metal, e.g., ruthenium, and L is the same or different and represents a substituted or unsubstituted amidinato group or a substituted or unsubstituted amidinato-like group, which process comprises (i) reacting a substituted or unsubstituted metal source compound, e.g., ruthenium (II) compound, with a substituted or unsubstituted amidinate or amidinate-like compound in the presence of a solvent and under reaction conditions sufficient to produce a reaction mixture comprising said organometallic compound, e.g., ruthenium (III) compound, and (ii) separating said organometallic compound from said reaction mixture. The organometallic compounds are useful in semiconductor applications as chemical vapor or atomic layer deposition precursors for film depositions.
US07816549B2 Metal-containing compound, its production method, metal-containing thin film, and its formation method
A compound which has thermal stability and moderate vaporizability and is satisfactory as a material for the CVD or ALD method; a process for producing the compound; a thin film formed from the compound as a raw material; and a method of forming the thin film. A compound represented by the general formula (1) is produced by reacting a compound represented by the general formula (2) with a compound represented by the general formula (3). The compound produced is used as a raw material to form a metal-containing thin film. [Chemical formula 1] (1) [Chemical formula 2] (2) [Chemical formula 3] Mp(NR4R5)q(3) (In the formulae, M represents a Group 4 element, aluminum, gallium, etc.; n is 2 or 3 according to cases; R1 and R3 each represents C1-6 alkyl, etc.; R2 represents C1-6 alkyl, etc.; R4 and R5 each represents C1-4 alkyl, etc.; X represents hydrogen, lithium, or sodium; p is 1 or 2 according to cases; and q is 4 or 6 according to cases).
US07816543B2 Leptomycin derivatives
Leptomycin derivatives having a moiety, such as a sulfide or a disulfide, that can conjugate to a cell binding reagent such as an antibody are disclosed. The therapeutic use of such leptomycin derivative conjugates is also described; such conjugates have therapeutic use because they can deliver cytotoxic leptomycin derivatives to a specific cell population in a targeted fashion.
US07816542B2 Compounds and compositions as TPO mimetics
The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated TPO activity, particularly diseases or disorders that involve thrombocytopenia.
US07816533B2 Asymmetric imine hydrogenation processes
A process for the catalytic hydrogenation or asymmetric hydrogenation of imines of Formula (I) to the corresponding amines of Formula (II) is provided in which R1 is aryl; R2 is aryl, cyclic, alkyl, alkenyl or alkynyl; and R3 is alkyl. The catalytic system includes a ruthenium complex containing (1) a diamine and (2) a diphosphine or two monodentate phosphines ligands. Such process also relates to the asymmetric hydrogenation of prochiral imines to the chiral amines using chiral ruthenium complexes bearing chiral diphosphines or chiral monodentate phosphines and chiral diamines.
US07816531B2 Metal complexes
The invention relates to novel metal complexes. Said compounds can be used as functional materials in a series of different types of applications that can be attributed in the broadest sense to the electronics industry The inventive compounds are defined by formula (1).
US07816524B2 Methods of preparing quinolone analogs
Compounds having formula 1 are produced by contacting a compound having formula(6A) with a compound having formula (7), or tautomers thereof, in the presence of a non-nucleophilic base, wherein V, A, Z, L, L1,W, X, B′, R and N are as defined herein.
US07816523B2 Potentiators of glutamate receptors
This application relates to a substituted hydroxyphenyl ketone compound of formula I, or a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof and its use in treating migraine. This application also relates to processes for preparing a compound of formula I, and intermediate compounds useful therein.
US07816522B2 Triazolone derivatives
A Compound represented by the following general formula (1), salts thereof or hydrates of the foregoing is a novel compound useful for treatment and/or prevention of diseases associated with thrombus formation, and which is safer with suitable physicochemical stability. [wherein R1a, R1b, R1c and R1d each independently represent hydrogen, etc.; R2 represents optionally substituted phenyl, etc.; R3 represents optionally substituted C6-10 aryl, etc.; and Z1 and Z2 each independently represent hydrogen]
US07816521B2 1,2,4-benzotriazine-1,4-dioxides
The compound 3-ethyl-6-[3-(4-morpholinyl)propoxy]-1,2,4-benzotriazine 1,4-dioxide and pharmacologically acceptable salts thereof. A method of treating cancer in a subject is also described in which 3-ethyl-6-[3-(4-morpholinyl)propoxy]-1,2,4-benzotriazine 1,4-dioxide or a pharmacologically acceptable salt thereof is administered to tumor cells in a hypoxic environment. Also described is a method of radiosensitising in a subject tumor cells of solid tumors in hypoxic conditions by administering to the subject a pharmaceutical composition containing 3-ethyl-6-[3-(4-morpholinyl)propoxy]-1,2,4-benzotriazine 1,4-dioxide or a pharmacologically acceptable salt thereof in an amount sufficient to produce radiosensitivity in the tumor cells, and subjecting the tumor cells to radiation. A pharmaceutical composition is additionally provided containing a therapeutically effective amount of 3-ethyl-6-[3-(4-morpholinyl)propoxy]-1,2,4-benzotriazine 1,4-dioxide or a pharmacologically acceptable salt thereof and a pharmaceutically acceptable excipient, adjuvant, carrier, buffer or stabiliser.
US07816518B2 Porphyrin derivatives and their use in photon activation therapy
The present invention relates to the use of a compound of formula (I) in the manufacture of a pharmaceuticals composition for cell death by photo activation therapy and the use of the compounds in the prevention and/or treatment of cancer.
US07816516B2 Conjugates of hydroxyalkyl starch and an active agent
The invention relates to compounds, comprising a conjugate of hydroxyalkyl starch (HAS) and an active agent, whereby the hydroxyalkyl starch is either directly covalently bonded to the active agent, or by means of a linker. The invention further relates to methods for the production of a covalent HAS-active agent conjugate, whereby HAS and an active agent are reacted in a reaction medium, characterised in that the reaction medium is water or a mixture of water and an organic solvent, comprising at least 10 wt. % water.
US07816514B2 Glucosamine and method of making glucosamine from microbial biomass
Glucosamine suitable for human or animal consumption is disclosed. The glucosamine is derived from fungal biomass containing chitin. Various methods of producing glucosamine by acid hydrolysis of fermented fungal biomass are also disclosed.
US07816504B2 PUFA polyketide synthase systems and uses thereof
The invention generally relates to polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems isolated from or derived from non-bacterial organisms, to homologues thereof, to isolated nucleic acid molecules and recombinant nucleic acid molecules encoding biologically active domains of such a PUFA PKS system, to genetically modified organisms comprising PUFA PKS systems, to methods of making and using such systems for the production of bioactive molecules of interest, and to novel methods for identifying new bacterial and non-bacterial microorganisms having such a PUFA PKS system.
US07816500B2 Antibody SACK-1 that binds CD44 glycoforms
Methods and compositions for modifying glycans (e.g., glycans expressed on the surface of live cells or cell particles) are provided herein.
US07816496B2 MN gene and protein
A new gene—MN—and proteins/polypeptides encoded therefrom are disclosed. Recombinant nucleic acid molecules for expressing MN proteins/polypeptides and recombinant proteins are provided. Expression of the MN gene is disclosed as being associated with tumorigenicity, and the invention concerns methods and compositions for detecting and/or quantitating MN antigen and/or MN-specific antibodies in vertebrate samples that are diagnostic/prognostic for neoplastic and pre-neoplastic disease. Test kits embodying the immunoassays of this invention are provided. MN-specific antibodies are disclosed that can be used diagnostically/prognostically, therapeutically, for imaging, and/or for affinity purification of MN proteins/polypeptides. Also provided are nucleic acid probes for the MN gene as well as test kits comprising said probes. The invention also concerns vaccines comprising MN proteins/polypeptides which are effective to immunize a vertebrate against neoplastic diseases associated with the expression of MN proteins. The invention still further concerns antisense nucleic acid sequences that can be used to inhibit MN gene expression, and polymerase chain reaction (PCR) assays to detect genetic rearrangements.
US07816495B2 Processes for the preparation of fibrinogen
The present invention relates to processes for the purification of fibrinogen, and to readily solubilised fibrinogen preparations.
US07816493B2 Soluble form of carbonic anhydrase IX (S-CA IX), assays to detect s-CA IX, CA IX'S coexpression with HER-2/NEU/C-ERBB-2, and CA IX-specific monoclonal antibodies to non-immunodominant epitopes
Disclosed herein is the discovery of a soluble MN/CA IX (s-CA IX) found in body fluids, such as, urine and serum. Soluble CA IX comprises the extracellular domain of CA IX or portions thereof. The predominant s-CA IX species is the extracellular domain comprising a proteoglycan-like (PG) domain and carbonic anhydrase (CA) domain, and having a molecular weight of about 50/54 kilodaltons. Diagnostic/prognostic methods for precancer/cancer that detect or detect and quantitate s-CA IX in body fluids, are described. Also disclosed is the coexpression of CA IX and HER-2 that provides potentially synergistic diagnostic/prognostic and therapeutic strategies for precancer/cancer. Further disclosed are new MN/CA IX-specific antibodies generated from MN/CA IX-deficient mice, useful diagnostically/prognostically and therapeutically for cancer/precancer. Preferred are new antibodies, specific for non-immunodominant epitopes of MN/CA IX, useful to detect soluble CA IX (s-CA IX) in body fluids, preferably in combination with antibodies specific to immunodominant epitopes of MN/CA IX.
US07816492B2 Human G protein-coupled receptors
The invention disclosed in this patent document relates to transmembrane receptors, more particularly to endogenous, human orphan G protein-coupled receptors.
US07816491B2 Ordered biological nanostructures formed from chaperonin polypeptides
The following application relates to nanotemplates, nanostructures, nanoarrays and nanodevices formed from wild-type and mutated chaperonin polypeptides, methods of producing such compositions, methods of using such compositions and particular chaperonin polypeptides that can be utilized in producing such compositions.
US07816489B2 Methods for making intermediates and oxytocin analogues
More efficient and/or economical methods for synthesizing heptapeptide alcohol analogs of oxytocin are provided along with novel intermediates which are useful in synthesizing such oxytocin analogs. Efficient and economical methods for synthesizing intermediates useful in synthesizing these oxytocin analogs are also provided.
US07816488B2 Method to estimate pent values
The PENT value for a resin may be estimated within ±10% by determining the % of heat flow to melt a fraction of a polymer above or below a set point and comparing it to a graph or algorithm of PENT values related to the % of heat flow to melt entire sample for a number of resins made using the same catalyst system. In a similar manner one may estimate the process conditions to prepare a polymer having a target PENT value based on the conditions used to prepare the samples for the graph or algorithms. The invention provides a simple procedure that may be used at a manufacturing site to estimate PENT values.
US07816485B2 Catalyzed preparation of (meth)acrylates of N-hydroxyalkylated amides
Process for catalytically preparing (meth)acrylates of N-hydroxyalkylated amides and use thereof.
US07816482B1 Epoxy-crosslinked sulfonated poly (phenylene) copolymer proton exchange membranes
An epoxy-crosslinked sulfonated poly(phenylene) copolymer composition used as proton exchange membranes, methods of making the same, and their use as proton exchange membranes (PEM) in hydrogen fuel cells, direct methanol fuel cell, in electrode casting solutions and electrodes, and in sulfur dioxide electrolyzers. These improved membranes are tougher, have higher temperature capability, and lower SO2 crossover rates.
US07816481B2 Polyether polyamine agents and mixtures thereof
Provided herein are polyamine precursors useful in the manufacture of epoxy resins. Use of a polyamine precursor according to the invention provides an epoxy resin formulation having an increased working time over prior art amines used for curing epoxies. Increased working times translate to the ability to manufacture composites which could not be made using conventional epoxy curing agents, such as composite blades for wind-driven turbines. Such polyamines are also useful in polyurea formulations for lengthening reaction time, thus allowing more flow of applied polyurea coatings prior to gellation.
US07816472B2 Polydiacetylene polymer compositions and methods of manufacture
Polyurethane-based polymer compositions that include diacetylene segments are provided.
US07816471B2 Process for producing photoresist polymeric compounds
Process for producing photoresist polymeric compound having repeated units corresponding to at least one monomer selected from monomer (a) having lactone skeleton, monomer (b) having group which becomes soluble in alkali by elimination with acid, and monomer (c) having alicyclic skeleton having hydroxyl group. Process includes (A) polymerizing mixture of monomers containing at least one monomer selected from the above monomers (a), (b), and (c), and (B) extracting polymer formed in the polymerization by using organic solvent and water to partition the formed polymer into organic solvent layer and metal component impurity into aqueous layer, or passing polymer solution, which contains polymer having repeated units corresponding to at least one of the above monomers (a), (b), and (c) and metal content of which is 1000 ppb by weight or less relative to the polymer through filter comprising porous polyolefin membrane having cation-exchange group. The photoresist polymeric compounds have a metallic impurity content that is extremely low.
US07816469B2 Process for producing polymer nanodispersions
This disclosure is generally directed to a batch process of producing semi-conductive polymer nanodispersions in which a composition comprising a liquid and a polymer is at least partially dissolved in the liquid, resulting in dissolved polymer molecules in the composition, wherein the dissolution occurs in a dissolution vessel. The solubility of the dissolved polymer molecules in the composition is then increased to increase the concentration of dissolved polymer in the composition to a range from about 0.1% to about 30% based on a total weight of the polymer and the liquid, wherein increasing the solubility of the dissolved polymer in the composition occurs in a dissolution vessel. The dissolved polymer in the composition is then diluted with a diluent, wherein the dissolution of the dissolved polymer in the composition occurs by addition of the composition to the diluent in a precipitation vessel.
US07816464B2 Polymer particle dispersion, cosmetic composition comprising it and cosmetic process using it
The present disclosure relates to a cosmetic composition comprising, in a cosmetically acceptable medium, at least one dispersion of polymer particles in a liquid silicone medium, the polymer being a copolymer comprising at least one first block that is soluble and at least one second block that is insoluble in the silicone medium.Another aspect of the present disclosure relates to a dispersion of polymer particles in a liquid silicone medium, and also to a cosmetic process for making up, cleansing, protecting against the sun, shaping, dyeing or caring for keratin materials, such as the body or facial skin, the nails, the hair and/or the eyelashes, and for use with the present composition.
US07816463B2 Glue for packaging light emitting diode and use thereof
A glue for packaging a light emitting diode (LED) is described and includes a first set of compositions and a second set of compositions mixed based on a predetermined weight ratio. The first set of compositions is poly(dimethyl siloxane), and the second set of compositions includes a copolymer of dimethyl siloxane, methyl hydrogen siloxane, and vinyl siloxane. The copolymer in the second set of compositions has a weight percentage from about 94% to 99%, dimethyl siloxane in the copolymer has a weight percentage from about 84% to 90%, methyl hydrogen siloxane in the copolymer has a weight percentage from about 4% to 9%, and vinyl siloxane in the copolymer has a weight percentage from about 2% to 7%. A use of the glue for packaging a LED is also described.
US07816462B2 Method for laminating using special cross-linked carbodiimide groups
A process for adhesively bonding a substrate, using an adhesive comprising a polymer binder and a crosslinker compound I comprising carbodiimide groups, wherein the compound comprising carbodiimide groups is obtainable by reacting a) carbodiimides of 1,3-bis(1-methyl-1-isocyanatoethyl)benzene, 1,4-bis(1-methyl-1-isocyanatoethyl)benzene or a mixture thereof with b) polyalkylene oxides having at least two isocyanate-reactive groups, preferably at least two hydroxyl groups, and c) if appropriate, further compounds reactive with a) or b).
US07816461B2 Block copolymers of polycarpolactone and poly (propylene funarate)
Poly(propylene fumarate) is copolymerized with poly(caprolactone) diol to produce a block copolymer of poly(propylene fumarate) and poly(caprolactone). The biocompatible and bioresorbable block copolymer of poly(propylene fumarate) and poly(caprolactone) is useful in the fabrication of injectable and in-situ hardening scaffolds for tissue and/or skeletal reconstruction. The block copolymer can be crosslinked by redox or photo-initiation, with or without an additional crosslinker. Thus, the copolymer is both self-crosslinkable (without the use of any crosslinkers) and photocrosslinkable (in the presence of photons such as UV light).
US07816456B2 Semicrystalline propylene polymer composition for producing biaxially stretched polypropylene films
The present invention relates to a semicrystalline propylene polymer composition prepared by polymerizing propylene, ethylene and/or C4-C18-1-alkenes, where at least 50 mol % of the monomer units present stem from the polymerization of propylene and at least 20% by weight of the propylene polymer composition is the result of a polymerization using metallocene catalysts, with a melting point TM of from 65 to 170° C., where the semicrystalline propylene polymer composition can be broken down into from 65 to 85% by weight of a principal component A, from 10 to 35% by weight of an ancillary component B and from 0 to 25% by weight of an ancillary component C.
US07816453B2 Adhesive compositions for bonding and filling large assemblies
Adhesive composition for bonding and filling large assemblies, including a mixture of about 5 percent to about 75 percent by weight of a thermoplastic polymer, about 0.5 percent to about 35 percent by weight of a polyester resin or vinyl ester resin, and about 20 percent to about 80 percent by weight of an alkyl acrylate or methacrylate monomer.
US07816450B2 Transparent thermoplastic blend of a cycloolefin copolymer and a thermoplastic polyurethane
A blend of a cycloolefin copolymer and a thermoplastic urethane having similar indices of refraction is transparent. The cycloolefin copolymer is derived from norbornene and other monomers such that it has a processing range compatible with the thermoplastic urethane. The urethane component preferably has a polyether intermediate. A thermoplastic urethane compatibilizing agent is utilized desirably having a hydrocarbon intermediate portion. The compositions can be made to have desirable electrical dissipative properties for static control applications.
US07816449B2 Coating composition for adhesion to olefinic substrates
The present invention is an adhesion promoter, a coating composition containing the adhesion promoter and a method for preparing the adhesion promoter and coating. The adhesion promoter of the present invention is an olefin based polymer prepared by reacting a hydroxy functional olefin polymer with a compound reactive with hydroxy functionality to provide functionality on the olefin polymer that is inert to reaction with a principal resin or crosslinking resin in a coating composition.
US07816447B2 Reactor systems and polymerization processes using multi-zone circulating reactors
The invention relates to the production of polymers using polymerization processes and reactor systems including a plurality of multi-zone circulating reactors. In particular, the invention relates to the production of impact copolymers using reactor systems including a plurality of multi-zone circulating reactors.
US07816446B2 Interpenetrated rubber particles and compositions including the same
Modified scrap rubber particles, a method for forming the modified rubber particles and compositions including the modified rubber particles. The rubber particles are impregnated with at least one polymerizable monomer and polymerized to impregnate the rubber particles with a polymer. The impregnated polymer provides the modified rubber particles with improved properties which increase the potential uses for recycled scrap rubber. The modified rubber particles are useful in surface coatings, such as latex paint or powder coatings and can be used as a soil substitute.
US07816445B2 Production method for hydrophilic polymer
The subject invention provides a hydrophilic polymer (water-absorbing resin) which is superior in performance and productivity. According to the production method of the present invention, a hydrophilichigh-molecular-weight compound is dispersed in an aqueous solution containing a hydrophilic monomer. The dispersed hydrophilic high-molecular-weight compound is dissolved by heat of neutralization (heat of hydration) and/or heat of polymerization generated in the process of producing a hydrophilic polymer.
US07816440B2 Flame retardant, flame-retardant resin composition and molded body
A flame retardant includes magnesium-hydroxide particles that contain at least one transitional metal compound. The at least one transitional metal compound is at least one compound selected from a group consisting of copper compound, cobalt compound, nickel compound, zinc compound and titanium compound. The at least one transitional metal compound is contained in the magnesium-hydroxide particles with the content of 100 to 1000 mass ppm in terms of metals. In addition, the total content of the copper compound, the cobalt compound and the nickel compound is 1000 mass ppm in terms of metals or less while the total content of the zinc compound and the titanium compound is 1000 mass ppm or less.
US07816439B2 Structures incorporating polymer-inorganic particle blends
Polymer-inorganic particle blends are incorporated into structures generally involving interfaces with additional materials that can be used advantageously for forming desirable devices. In some embodiments, the structures are optical structures, and the interfaces are optical interfaces. The different materials at the interface can have differences in index-of-refraction to yield desired optical properties at the interface. In some embodiments, structures are formed with periodic variations in index-of-refraction. In particular, photonic crystals can be formed. Suitable methods can be used to form the desired structures.
US07816438B2 Flame-retardant polyamide composition
To provide a polyamide resin composition which inhibits generation of a gas, formation of decomposition products and discoloration of molded articles even under high molding temperature conditions, is excellent in incombustibility and toughness, and heat resistance in a reflow soldering step being required for surface mounting. The present invention provides a flame-retardant polyamide composition comprising 20 to 80% by mass of polyamide (A), 5 to 40% by mass of a flame retardant (B), 0.01 to 0.45% by mass of an antimony compound (C) and 0.5 to 10% by mass of a salt of zinc or calcium (D).
US07816436B2 Carbon black with large primary particle size as reheat additive for polyester and polypropylene resins
Reheat characteristics of polyethylene and polypropylene resins, including reheating time and resin color, are improved by adding to the resin carbon black with a primary particle size in the range of 200 to 500 nm as an infrared absorber. Thermal carbon blacks having this primary particle size are preferred over Furnace carbon blacks. Injection stretch-blow molded bottles and other thermoformed products are made from resins with carbon black infrared absorber.
US07816433B2 Polyacetal resin composition and article thereof
A polyacetal resin composition comprising (A) 100 parts by mass of polyacetal resin generating formaldehyde in an amount of not more than 100 ppm when heated at a temperature of 200° C. for 50 minutes under the nitrogen atmosphere and (B) 0.01 to 5 parts by mass of a hydrazide compound can provide an article which is remarkably reduced in an emission amount of formaldehyde even though molded either at a higher temperature or under molding conditions wherein the resin temperature rises partially. Therefore, the polyacetal resin composition can be molded according to various molding methods and under a wide range of molding conditions. The article molded from the resin composition has succeeded in reducing the emission amount of formaldehyde, measured according to VDA275 method, to not more than 1 mg/kg, the level never achieved before, and therefore is usable for various applications where a reduced VOC is required.
US07816431B2 Composite compositions
Disclosed are composite compositions well suited for forming shaped articles which comprise thermoplastic polymer, cellulose, a coupling agent comprising anhydride moities, and a lubricant comprising an alkyl ester of carboxylic acid. Preferably the lubricant is substantially free of zinc stearate.
US07816425B2 Ink composition
A surfactant selected from an acrylate-modified polydimethylsiloxane or a polyether-modified polydimethylsiloxane is used, together with at least a colorant and a UV-curable organic diluent, in a non-aqueous UV-curable ink composition suitable for ink jet printing. The use of this type of surfactant prevents the ink composition from causing the loss of more than 5% of the nozzles in an ink jet print head and enables the composition to provide a hole to area ratio of no more than 0.05. The present ink compositions have particular application in the printing of packaging for foodstuffs.
US07816418B2 Universal primer
A radiation-curable composition comprising a radiation-curable compounds a free acid and a halogenated polyolefin is disclosed. The compositions are useful in the repair of damaged motor vehicle body parts.
US07816408B2 Calcium receptor active compounds
A novel calcium receptor active compound having the formula is provided: Ar1—[CR1R2]p—X—[CR3R4]q—[CR5R6]—NR7—[CR8R9]—Ar2 wherein: Ar1 is selected from the group consisting of aryl, heteroaryl, bis(arylmethyl)amino, bis(heteroarylmethyl)amino and arylmethyl(heteroarylmethyl)amino; X is selected from the group consisting of oxygen, sulfur, sulfinyl, sulfonyl, carbonyl and amino; R1, R2, R3, R4, R5, R6, R7, R8 and R9 are, for example, hydrogen or alkyl; Ar2 is selected from the group consisting of aryl and heteroaryl; p is an integer of from 0 to 6, inclusive; and, q is an integer of from 0 to 14, inclusive.
US07816404B2 Methods for the preparation and use of ferric pyrophosphate citrate chelate compositions
A highly water soluble ferric pyrophosphate citrate chelate useful for treating iron deficiency contains 2% or less phosphate by weight. These chelate compositions are easily milled and/or processed into dosage forms using conventional techniques, and are expected to exhibit advantageous biocompatibility as compared to conventional soluble ferric pyrophosphates, ferric salts, ferric polysaccharide complexes and ferrous salts.
US07816402B2 Compositions and methods for the treatment of skin
An ascorbic acid-based composition and related method for the treatment of aging, photo-damaged or inflamed skin is disclosed. The composition includes water and ascorbic acid, at least a portion of which has generally been pretreated by being dissolved under relatively high temperature and concentration conditions. The composition typically includes at least about 5.0% (w/v) ascorbic acid formulated to have a pH above 3.5. 10 to 50% of the ascorbic acid is pretreated ascorbic acid. The composition may also include a non-toxic zinc salt, a tyrosine compound, and/or pharmaceutically acceptable carrier. The composition may include an anti-inflammatory compound, such as aminosugar and/or sulfur-containing anti-inflammatory compound. Embodiments containing an aminosugar such as glucosamine are further useful for treating rosacea and other inflammatory skin ailments. The composition may be administered in a variety of forms suitable for topical application on skin.
US07816401B2 Process for total synthesis of pladienolide B and pladienolide D
A process for producing a compound represented by Formula (11): wherein P1, P7, P8, P9 and R1 are the same as defined herein, characterized by including reacting a compound represented by Formula (12): with a compound represented by Formula (13): in the presence of a catalyst.
US07816396B1 Method for increasing the bioavailability of glycopyrrolate
The invention relates to a method of treating sialorrhea in a human patient, which comprises orally administering glycopyrrolate in a liquid solution to the human patient under fasted conditions.
US07816394B2 Methods of transdermally administering an indole serotonin receptor agonist and transdermal compositions for use in the same
Methods of transdermally delivering a therapeutic amount of an indole serotonin receptor agonist to an individual in need thereof, e.g., to provide a therapeutic level of an indole serotonin receptor agonist to an individual in need thereof, are provided. Also provided are transdermal formulations of indole serotonin receptor agonists that find use in practicing the subject methods.
US07816393B2 Isoindoline compounds and methods of their use
Novel isoindoline compounds are disclosed. Methods of treating, preventing and/or managing cancer, diseases and disorders associated with, or characterized by, undesired angiogenesis, and diseases and disorders mediated by PDE 4, using the compounds are also disclosed.
US07816391B2 Chemical compounds
A compound of formula (I): and pharmaceutically-acceptable salts thereof wherein the variable groups are defined within; their use in the inhibition of 11βHSD1, processes for making them and pharmaceutical compositions comprising them are also described.
US07816385B2 Dimeric dicarboxylic acid derivatives, their preparation and use
A novel class of dicarboxylic acid derivatives, the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in the treatment and/or prevention of conditions mediated by Peroxisome Proliferator -Activated Receptors (PPAR).
US07816382B2 Linear urea mimics antagonists of P2Y1 receptor useful in the treatment of thrombotic condition
The present invention provides novel urea mimics and analogues of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, B, W, and R6 are as defined herein. These compounds are selective inhibitors of the human P2Y1 receptor which can be used as medicaments.
US07816379B2 Oxazolidinone derivatives
The present invention relates to novel derivatives of oxazolidinone, a method thereof and pharmaceutical compositions comprising the derivatives for use in an antibiotic. The oxazolidinone derivatives of the present invention show inhibitory activity against a broad spectrum of bacteria and lower toxicity. The prodrugs, prepared by reacting the compound having hydroxyl group with amino acid or phosphate, have an excellent efficiency on solubility thereof against water. Further, the derivatives of the present invention may exert potent antibacterial activity versus various human and animal pathogens, including Gram-positive bacteria such as Staphylococi, Enterococci and Streptococi, anaerobic microorganisms such as Bacteroides and Clostridia, and acid-resistant microorganisms such as Mycobacterium tuberculosis and Mycobacterium avium. Accordingly, the compositions comprising the oxazolidinone are used in an antibiotic.
US07816377B2 Tubulysin analogues
The invention relates to tubulysin derivatives of general formula (II), said derivatives having a cytostatic effect.
US07816375B2 Ligands for monoamine receptors and transporters, and methods of use thereof
One aspect of the present invention relates to heterocyclic compounds. A second aspect of the present invention relates to the use of the heterocyclic compounds as ligands for various mammalian cellular receptors, including dopamine, serotonin, or norepinephrine transporters. The compounds of the present invention will find use in the treatment of numerous ailments, conditions and diseases which afflict mammals, including but not limited to addiction, anxiety, depression, sexual dysfunction, hypertension, migraine, Alzheimer's disease, obesity, emesis, psychosis, schizophrenia, Parkinson's disease, inflammatory pain, neuropathic pain, Lesche-Nyhane disease, Wilson's disease, and Tourette's syndrome. An additional aspect of the present invention relates to the synthesis of combinatorial libraries of the heterocyclic compounds, and the screening of those libraries for biological activity, e.g., in assays based on dopamine transporters.
US07816373B2 Method for improving adsorption of a drug from ethylene oxide derivative
The present invention relates to a method for improving adsorption on the gastrointestinal mucous layers of one or more selected from polyethylene glycol, polyethylene oxide, and polyoxyethylene polypropylene copolymer wherein the average number of repeating oxyethylene units of one ethylene oxide chain length is 17 or greater. It is possible to enhance pharmacological effects by using the present invention with drugs that have anti-H. pylori activity.
US07816371B2 Bicycloheteroaryl compounds as P2X7 modulators and uses thereof
Bicycloheteroaryl compounds are disclosed that have a formula represented by the following: The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, traumatic injury, and others.
US07816369B2 Mediators of hedgehog signaling pathways, compositions and uses related thereto
The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function comprising contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize smoothened or hedgehog activity.
US07816368B2 Pyridoindolone derivatives substituted in the 3-position by a heterocyclic group, their preparation and their application in therapeutics
The present disclosure relates to pyridoindolone derivatives of general formula (I): in which R1 to R5 are as defined in the specification, to processes for preparing said derivatives, and to methods of use thereof.
US07816366B2 Compositions and methods for treating and preventing dermatoses
The invention encompasses protectant agents including uracil or a metabolite thereof that effectively prevent and/or treat the cutaneous toxicities and dermatological side-effects associated with chemotherapeutic agents. Additionally, and surprisingly compositions including uracil or a metabolite thereof are effective for treating or preventing various dermatoses.
US07816359B2 N-phenyl-2-pyrimidine-amine derivatives
The present invention relates to novel amides and a process for preparing these amides.
US07816358B2 Pharmaceutical formulations comprising N,N′-disubstituted piperazine compounds
Pharmaceutical formulations comprising N,N′disubstituted piperazine compounds and related methods of treatment using these formulations.
US07816355B1 Processes for the preparation of rivaroxaban and intermediates thereof
This invention provides a process for the preparation of S-Rivaroxaban and/or R-Rivaroxaban comprising reacting, in the presence of a first base, a compound of Formula 9: with a compound of Formula 8:
US07816352B2 Apoptosis inhibitors
The present invention provides compounds that act as selective agents to protect against unintentional cell death or tissue damage and can relieve side effects of cancer treatment such as, for example, oral mucositis, hair loss, diarrhea due to damage to the gastrointestinal epithelium, and myelosuppression. In addition, these compounds can be used to prevent premature cell death when the cell death is caused by signals from damaged cells, for example, signals generated as the result of a traumatic incident or an ischemic episode.
US07816349B2 Substituted pyrrolidinones as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1
The present invention discloses novel compounds of Formula I: (I) possessing 11β-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula I, as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, cognitive disorders, and other conditions associated with 11β-HSD type 1 activity.
US07816347B2 Pharmaceutical compositions comprising NEP-inhibitors, inhibitors of the endogenous endothelin producing system and HMG CoA reductase inhibitors
A combination therapy is disclosed for treating or inhibiting cardiovascular or metabolic diseases or conditions through a combination of at least one inhibitor of neutral endopeptidase (=NEP), at least one inhibitor of the endogenous endothelin producing system and at least one HMG CoA reductase inhibitor. Pharmaceutical compositions are also described comprising NEP inhibitors, inhibitors of the endogenous endothelin producing system and HMG CoA reductase inhibitors and the use of these pharmaceutical composition in the prophylaxis or treatment of cardiovascular and/or metabolic disorders or diseases in mammals (including humans).
US07816346B2 Analogs of ansamycin and pharmaceutical compositions thereof
Analogs of geldanamycin (an ansamycin), pharmaceutical formulations comprising such analogs, and methods of use (e.g., treating tumors).
US07816343B2 Wood preservative composition
A wood preservative composition comprising a mixture of a fungicide which is a combination of a boric acid ester, which is soluble in an organic solvent and has a sterically hindered di-alcohol or tri-alcohol group, such as trihexylene glycol biborate, an organo-iodine compound, a triazole, and a synthetic pyrethroid insecticide, said fungicide and the insecticide being present in a sufficient amount that wood treated with the wood treatment material contains fungicide and insecticide in an amount of about 1 ppm to 5000 ppm, based on the weight of the wood after treatment.
US07816341B2 Homogeneous, thermoreversible gel containing reduced viscosity carrageenan and products made therefrom
The present invention is directed to a homogeneous, thermoreversible gel comprising carrageenan wherein the carrageenan has a viscosity of less than 10 cP at 75° C. when measured in a 0.10 molar aqueous sodium chloride solution containing 1.5% by weight of the carrageenan based on the weight of all components in the solution, and optionally at least one of a plasticizer, a second film former, a bulking agent, and a pH controlling agent, wherein the gel has a solids content of at least 40%. The present invention is also directed to processes for the preparation thereof, as well as to variety of products containing the gel including edible products, soft capsules, hard capsules and solid forms encapsulating powders, tablets, caplets, etc.
US07816340B2 Oral immunostimulation of fish from (1-4) linked β-D-mannuronic acid
An oral, immunostimulating material for mammals, birds, fish, and reptiles comprising an immunostimulating amount of an alginate having a M content of at least 40% and an acceptable carriers.
US07816337B2 Reversible attachment of a membrane active polymer to a polynucleotide
Described is a process for delivering a biologically active compound to a cell by reversibly linking the compound to a membrane active polymer. In particular, polymer-polynucleotide conjugates are described. Methods for reversibly modifying the polymers to decrease cellular toxicity and improve efficacy are provided.
US07816328B2 Substituted fused heterocyclic C-glycosides
This invention relates to substituted fused heterocyclic C-glycosides, compositions containing them, and methods of using them, for example, for the treatment or prophylaxis of diabetes and Syndrome X.
US07816325B2 Secondary binding site of dipeptidyl peptidase IV (DP IV)
The present application relates to the secondary binding site of dipeptidyl peptidase IV, its relationship amongst substrates and to the modulation of substrate specificity of dipeptidyl peptidase IV (DP IV, synonym: DPP IV, CD26, EC 3.4.14.5). The application relates further to compounds that bind to the secondary binding site of DP IV and their use to modulate the substrate specificity of DP IV; methods of treatment of various DP IV mediated disorders; and screening methods for the identification of secondary binding sites on DP IV and DP IV-like enzymes.
US07816324B2 Composition and method for the treatment of diseases affected by a peptide receptor
The present invention includes peptidomimetic compound compositions and methods of making and using peptidomimetic compounds to modulate the activity of a peptide receptor for the treatment of one or more of hyperglycemia, insulin resistance, hyperinsulinemia, obesity, hyperlipidemia, hyperlipoproteinemia or other symptoms that relate to the function of the targeted receptor. The peptidomimetic includes an oligo-benzamide compound having at least three optionally substituted benzamides.
US07816321B2 Thymosin β4 derivatives and use thereof
The present invention relates to thymosin β4 (Tβ4) derivatives, Gly-Tβ4 and Ala-Tβ4. The present invention further relates to a pharmaceutical composition comprising the said Tβ4 derivatives. The present invention also relates to the use of said Tβ4 derivatives in manufacture of a medicament for treatment of skin lesion, heart injury, corneal lesion and/or coronary heart disease. The present invention further relates to a method of treatment for skin lesion, heart injury, corneal lesion and/or coronary heart disease by using the said Tβ4 derivatives.
US07816319B2 Methods and products for manipulating uncoupling protein expression
The invention is based in part on the discovery that uncoupling proteins (UCPs) are expressed in the plasma membrane of rapidly dividing cells but not of growth arrested, chemotherapy resistant cells. It has also been found according to the invention that UCP is expressed in the lysosomal membrane under certain metabolic conditions. Thus the invention is methods, products, screening assays and kits relating to the manipulation of UCP expression within cellular and intracellular membranes.
US07816316B2 Sustained release drug carrier
The present invention aims to provide completely biodegradable and biocompatible sustained-release carriers for proteins or peptides, which allow encapsulation of the proteins or peptides at high encapsulation rates without inhibiting their biological activity. The present invention provides a method for preparing a sustained-release carrier, wherein in a solution in the presence of a protein or a peptide, a hyaluronic acid derivative having an unsaturated bond(s) or a mercapto group(s) introduced into hyaluronic acid is chemically crosslinked with a mercapto group-containing compound or an unsaturated bond-containing compound, respectively, to give a hydrogel. The method of the present invention enables efficient encapsulation of proteins or peptides while retaining their biological activity.
US07816315B2 Method of isolating a nucleic acid using a material containing an amino group and a carboxyl group and positively charged at a first pH and a solid material for nucleic acid isolation used for the method
Provided are a method of isolating a nucleic acid from a sample and a solid material for isolating the nucleic acid which can be used for the above method. The method includes contacting the sample with a bifunctional material containing an amino group and a carboxyl group at a first pH to bind the nucleic acid to the bifunctional material, the bifunctional material being positively charged at the first pH; and releasing the nucleic acid at a second pH which is higher than the first pH.
US07816314B2 Automatic dishwashing compositions and methods for use with electrochemical cells and/or electrolytic devices
The present invention relates to automatic dishwashing detergent compositions and methods of using compositions comprising halogenated salts, phosphate and/or silicate in conjunction with electrolyzed water in automatic dishwashing appliances comprising an electrochemical cell and/or electrolytic device for treating tableware to improve cleaning, sanitizing and stain removal by controlling hardness, corrosion and dispersancy.
US07816313B2 Photoresist residue remover composition and semiconductor circuit element production process employing the same
A photoresist residue remover composition is provided that removes a photoresist residue formed by a resist ashing treatment after dry etching in a step of forming, on a substrate surface, wiring of any metal of aluminum, copper, tungsten, and an alloy having any of these metals as a main component, the composition including one or two or more types of inorganic acid and one or two or more types of inorganic fluorine compound. There is also provided a process for producing a semiconductor circuit element wherein, in a step of forming wiring of any metal of aluminum, copper, tungsten, and an alloy having any of these metals as a main component, the photoresist residue remover composition is used for removing a photoresist residue formed by a resist ashing treatment after dry etching.
US07816312B2 Composition for photoresist stripping solution and process of photoresist stripping
The present invention provides a composition for photoresist stripping solution which shows a superior stripping property of photoresists and damaged photoresist layers remained after dry etching in the fabrication process of semiconductor circuit devices, without attacking new wiring materials and interlayer insulating film materials, as well as a process of stripping of photoresists and damaged photoresist layers. The composition for photoresist stripping solution which contains at least one of acetylene alcohol compounds and organic sulfonic acid compounds, and at least one of polyvalent alcohols and their derivatives is used.
US07816307B2 Powder mixture suitable for sintering to form a self-lubricating solid material
The invention relates to a novel self-lubricating solid material; to a method of preparing such a material from a powder mixture; to said powder mixture; and to mechanical parts made of said novel material. Said powder mixture comprises a powder of a metal alloy that is a precursor for the matrix of said material, particles of a first solid lubricant such as CeF3 that are for insertion in said matrix without reacting with said metal alloy, and particles of a second solid lubricant such as WS2 or MoS2 for reacting with a component of said metal alloy during sintering of the powder to form a lubricating phase. Said material can be used for fabricating a bushing that is to receive a root of a variable-pitch vane of an airplane turbojet compressor.
US07816306B2 Lubricant composition for hot forming
The present invention provides a lubricant composition for hot forming which makes it possible to provide lubricity at 80° C. or more without being peeled or washed by the roll cooling water, and which is easily washed under 40° C. without having water resistance. The lubricant composition for hot forming of the present invention comprises: a solid lubricant from 10 to 40% by mass; water-dispersible synthetic resin from 5 to 20% by mass; inorganic acid amine salt from 0.5 to 5% by mass; and water from 45 to 80% by mass.
US07816304B2 Mass labels
Provided herein are sets of mass labels. Each mass label in a set includes: 1) a mass marker moiety; 2) a mass normalisation moiety; and 3) a cleavable linker connecting the mass marker moiety to the mass normalisation moiety. Each mass marker moiety is characterized as having a mass different from that of all other mass marker moieties in the set as determined by mass spectrometry. Further, each mass normalization moiety ensures that each mass label in the set has substantially the same mass as determined by mass spectrometry.
US07816301B2 Aqueous-liquid-absorbing agent and its production process
The present invention provides an aqueous-liquid-absorbing agent which comprises water-absorbent resin particles as essential components and is suitable for uses in sanitary materials. The aqueous-liquid-absorbing agent according to the present invention is an aqueous-liquid-absorbing agent comprising water-absorbent resin particles as essential components, wherein the water-absorbent resin particles are obtained by a process including the step of polymerizing a water-soluble ethylenically unsaturated monomer having a carboxyl group, and have a crosslinked structure in their inside, the aqueous-liquid-absorbing agent exhibiting a water absorption capacity (CRC) of 5 to 25 g/g and a saline flow conductivity (SFC) of not less than 1216 cm3·s·10−7/g.
US07816300B2 Catalyst for purifying exhaust gas
The present invention provides an exhaust gas purification catalyst comprising a base material, and a two or more layered catalyst coating layer, formed on the base material, wherein the two or more layers have upper and lower layers, and wherein the upper layer contains a large amount of noble metal per liter of the base material more than that of the lower layer, and the lower layer contains a large amount of an oxygen storage/release material per liter of the base material more than that of the upper layer. This exhaust gas purification catalyst has more excellent H2S purifying performance than conventional catalysts while maintaining purifying performance against NOx and the other exhaust gas components.
US07816299B2 Hydrotreating catalyst system suitable for use in hydrotreating hydrocarbonaceous feedstreams
A stacked bed catalyst system comprising at least one first catalyst selected from conventional hydrotreating catalyst having an average pore diameter of greater than about 10 nm and at least one second catalyst comprising a bulk metal hydrotreating catalyst comprised of at least one Group VIII non-noble metal and at least one Group VIB metal and optionally a binder material.
US07816296B2 Hindered polyalicyclic alkyl catalysts and their use in a gas-phase polymerization reactor
Embodiments of the present invention include a method of polymerizing olefins comprising contacting olefins with a catalyst composition made by the process of combining a hindered polyalicyclic alkyl catalyst precursor with a particulate inorganic oxide for a deposition time greater than 2 hours to form a catalyst composition. Embodiments of the present invention also include catalyst compositions comprising a hindered polyalicyclic alkyl catalyst precursor made by the process of combining the hindered polyalicyclic alkyl catalyst precursor with a particulate inorganic oxide for a deposition time greater than 2 hours to form the catalyst composition. In one embodiment, the hindered polyalicyclic alkyl catalyst precursor is formed by first combining an acid, a compound having the formula RX, and a metal oxide selected from the group consisting of Group 3 to Group 10 oxide compounds to produce a catalyst precursor; characterized in that R is selected from the group consisting of hindered polyalicyclic alkyls, and substituted derivatives thereof, and X is selected from the group consisting of any suitable leaving group.
US07816288B2 Fabrics for therapeutic skin care bedding
A fabric for bedding which includes a woven fabric having warp yarns and filling yarns woven to provide a smooth fabric surface. One of the warp or filling yarns being at least 40% by weight of the fabric of continuous filament nylon, and the other of the warp or filling yarns being from about 0% to 60% by weight of the fabric of continuous filament polyester or nylon having non-round filament cross sections. An antimicrobial substance is topically applied or inherently available in the fabric.
US07816285B2 Patterned application of activated carbon ink
An odor control substrate that is applied with an activated carbon ink is provided. The activated carbon ink is applied in a pattern that covers from about 25% to about 95% of the surface area of the substrate. Although not covering the entire surface, the present inventors have discovered that the activated carbon ink is still capable of providing good odor reduction qualities to the substrate. To further enhance the aesthetic appeal of the odor control substrate to a consumer, one or more colored inks may also be applied the substrate in a pattern that may or may not overlap with the activated carbon ink pattern. The colored ink(s) may contrast well with the activated carbon ink to provide an overall design that is more aesthetically than otherwise would be provided by a uniform coating of activated carbon ink.
US07816283B2 Method of depositing a higher permittivity dielectric film
A method of depositing a high permittivity dielectric film on a doped silicon or silicon compound layer of a wafer. The method includes a first step of nitriding a specific element (A) such as hafnium Hf to form a nitride film (AxNy) on the silicon layer, wherein the specific element (A) and nitrogen (N) in the nitride film (AxNy) have a predetermined fraction relationship between x and y; a second step of oxidizing the nitride film in a oxygen atmosphere to form the dielectric film (AON).
US07816281B2 Method for manufacturing a semiconductor device
A method for manufacturing a semiconductor device includes the steps of forming a silicon oxide film on a silicon substrate, and forming a silicon nitride film on the silicon oxide film. The step of forming the silicon nitride film includes the steps of growing a first silicon layer having a thickness larger than a thickness of a monoatomic silicon layer, nitriding the first silicon layer to form a first silicon nitride layer, growing a second silicon layer on the first silicon layer on the first silicon nitride layer, and nitriding the second silicon oxide layer to form a second silicon nitride layer.
US07816277B2 Method for forming deposit, droplet ejection apparatus, electro-optic device, and liquid crystal display
A deposit forming method including ejecting droplets of a deposit forming material onto a substrate, thereby forming a deposit by the droplets on the substrate, is provided. The droplets are ejected along a direction inclined at a predetermined angle in a predetermined direction with respect to a normal line of the substrate and at a predetermined pitch in the predetermined direction. The predetermined angle is set in correspondence with the diameter of each of the droplets and the predetermined pitch in such a manner that the dimension of a dot formed by each droplet on the substrate in the predetermined direction becomes greater than or equal to the predetermined pitch.
US07816273B2 Technique for removing resist material after high dose implantation in a semiconductor device
Resist masks exposed to high-dose implantation processes may be efficiently removed on the basis of a combination of a plasma-based etch process and a wet chemical etch recipe, wherein both etch steps may include a highly selective etch chemistry in order to minimize substrate material loss and thus dopant loss in sophisticated semiconductor devices. The first plasma-based etch step may provide under-etched areas of the resist mask, which may then be efficiently removed on the basis of the wet chemical etch process.
US07816270B2 Method of forming minute patterns in semiconductor device using double patterning
A method of forming minute patterns in a semiconductor device, and more particularly, a method of forming minute patterns in a semiconductor device having an even number of insert patterns between basic patterns by double patterning including insert patterns between a first basic pattern and a second basic pattern which are transversely separated from each other on a semiconductor substrate, wherein a first insert pattern and a second insert pattern are alternately repeated to form the insert patterns, the method includes the operation of performing a partial etching toward the second insert pattern adjacent to the second basic pattern, or the operation of forming a shielding layer pattern, thereby forming the even number of insert patterns.
US07816269B2 Plasma deposition apparatus and method for making polycrystalline silicon
A plasma deposition apparatus for making polycrystalline silicon including a chamber for depositing said polycrystalline silicon, the chamber having an exhaust system for recovering un-deposited gases; a support located within the deposition chamber for holding a target substrate having a deposition surface, the deposition surface defining a deposition zone; at least one induction coupled plasma torch located within the deposition chamber and spaced apart from the support, the at least one induction coupled plasma torch producing a plasma flame that is substantially perpendicular to the deposition surface, the plasma flame defining a reaction zone for reacting at least one precursor gas source to produce the polycrystalline silicon for depositing a layer of the polycrystalline silicon the deposition surface.
US07816268B2 Semiconductor device and manufacturing method of semiconductor device
To provide a semiconductor device having a structure in which a barrier metal film containing nitrogen is formed in a connection surface between a copper alloy wiring and a via, in which the electric resistance between the copper alloy wiring and the via can be prevented from rising, and the electric resistance can be prevented from varying. A semiconductor device according to the present invention comprises a first copper alloy wiring, a via and a first barrier metal film. The first copper alloy wiring is formed in an interlayer insulation film and contains a predetermined additive element in a main component Cu. The via is formed in an interlayer insulation film and electrically connected to the upper surface of the first copper alloy wiring. The first barrier metal film is formed so as to be in contact with the first copper alloy wiring in the connection part between the first copper alloy wiring and the via and contains nitrogen. The predetermined additive element reacts with nitrogen to form a high-resistance part. In addition, the concentration of the predetermined additive element is not more than 0.04 wt %.
US07816266B2 Copper diffusion barrier
The invention concerns a method of forming a copper portion surrounded by an insulating material in an integrated circuit structure, the insulating material being a first oxide, the method having steps including forming a composite material over a region of the insulating material where the copper portion is to be formed, the composite material having first and second materials, annealing such that the second material reacts with the insulating material to form a second oxide that provides a diffusion barrier to copper; and depositing a copper layer over the composite material by electrochemical deposition to form the copper portion.
US07816263B2 Method for manufacturing thin film transistor
Disclosed is a method for manufacturing a thin film transistor having high resolution and high pattern accuracy with high production efficiency. Particularly disclosed is a method for manufacturing a thin film transistor wherein there is prevented deterioration of semiconductor properties in a plating step for electrode formation. This method is characterized in that a source electrode or a drain electrode is formed by such a process wherein a protective film is formed on an organic semiconductor layer, then a plating catalyst pattern is formed thereon by supplying a liquid containing a plating catalyst, and then a plating agent is brought into contact with the pattern.
US07816262B2 Method and algorithm for random half pitched interconnect layout with constant spacing
An embodiment of a system and method produces a random half pitched interconnect layout. A first normal-pitch mask and a second normal-pitch mask are created from a metallization layout having random metal shapes. The lines and spaces of the first mask are printed at normal pitch and then the lines are shrunk to half pitch on mask material. First spacers are used to generate a half pitch dimension along the outside of the lines of the first mask. The mask material outside of the first spacer pattern is partially removed. The spacers are removed and the process is repeated with the second mask. The mask material remains at the locations of first set of spacers and/or the second set of spacers to create a half pitch interconnect mask with constant spaces.In an embodiment, the half pitch interconnect mask is used to create a metallization interconnect layer with area of constant spacing and area of metallization. In an embodiment, an insulating dielectric is left unetched in the areas of constant spacing, and a conductor is deposited inside the etched out areas.
US07816258B2 Method for manufacturing electro-optic device substrate with titanium silicide regions formed within
An electro-optic device substrate includes a base and a TFT element having a source region and a drain region disposed on the base. The TFT element includes a silicon layer in the source region or the drain region, and the silicon layer at least partially includes a silicided portion. The electro-optic device substrate also includes a metal wire connected to the silicided portion of the silicon layer.
US07816256B2 Process for improving the reliability of interconnect structures and resulting structure
An interconnect structure of an integrated circuit having improved reliability and a method for forming the same are provided. The method includes providing a substrate, forming a dielectric layer overlying the substrate, performing a first shrinking process, wherein the dielectric layer shrinks and has a first shrinkage rate, forming a conductive feature in the dielectric layer after the step of performing the first shrinking process, and performing a second shrinking process after the step of forming the conductive feature, wherein the dielectric layer substantially shrinks and has a second shrinkage rate.
US07816255B2 Methods of forming a semiconductor device including a diffusion barrier film
Methods of forming a semiconductor device that includes a diffusion barrier film are provided. The diffusion barrier film includes a metal nitride formed by using a MOCVD process and partially treated with a plasma treatment. Thus, a specific resistance of the diffusion barrier film can be decreased, and the diffusion barrier film may have distinguished barrier characteristics.
US07816254B2 Film forming method, fabrication process of semiconductor device, computer-readable recording medium and sputtering apparatus
A film-forming method for forming a metal film on a substrate by a sputtering process includes the steps of depressurizing a processing space, in which deposition of the metal film is caused by the sputtering process, applying a DC bias voltage between the substrate and a target disposed in the processing space so as to face the substrate, and igniting plasma by introducing secondary electrons to the processing space from a secondary electron source.
US07816253B2 Surface treatment of inter-layer dielectric
When an interconnect structure is built on porous ultra low k (ULK) material, the bottom of the trench and/or via is usually damaged by a following metallization process which may be suitable for dense higher dielectric materials. Embodiment of the present invention may provide a method of forming an interconnect structure on an inter-layer dielectric (ILD) material. The method includes steps of treating an exposed area of said ILD material to create a densified area, and metallizing said densified area.
US07816251B2 Formation of circuitry with modification of feature height
A connection component for mounting a chip or other microelectronic element is formed from a starting unit including posts projecting from a dielectric element by crushing or otherwise reducing the height of at least some of the posts.
US07816246B2 Methods of making semiconductor fuses
Fuses for integrated circuits and semiconductor devices and methods for using the same. The semiconductor fuse contains two conductive layers, an overlying and underlying refractory metal nitride layer, on an insulating substrate. The semiconductor fuse may be fabricated during manufacture of a local interconnect structure including the same materials. The fuse, which may be used to program redundant circuitry, may be blown by electrical current rather than laser beams, thus allowing the fuse width to be smaller than prior art fuses blown by laser beams. The fuse may also be blown by less electrical current than the current required to blow conventional polysilicon fuses having similar dimensions.
US07816243B2 Semiconductor device and method of fabricating the same
A semiconductor device and a method of fabricating the same are described. A substrate having a PMOS area and an NMOS area is provided. A high-k layer is formed on the substrate. A first cap layer is formed on the high-k layer in the PMOS area, and a second cap layer is formed on the high-k layer in the NMOS area, wherein the first cap layer is different from the second cap layer. A metal layer and a polysilicon layer are sequentially formed on the first and second cap layers. The polysilicon layer, the metal layer, the first cap layer, the second cap layer and the high-k layer are patterned to form first and second gate structures respectively in the PMOS and NMOS areas. First source/drain regions are formed in the substrate beside the first gate structure. Second source/drain regions are formed in the substrate beside the second gate structure.
US07816228B2 Method of manufacturing a semiconductor device
In a method of manufacturing a semiconductor device including a planar type transistor and a fin type transistor, a substrate having a first region and a second region is partially to form an isolation trench defining an isolation region and an active region. An insulation layer liner is formed on sidewalls of the isolation trench in the first region and the second region. An isolation layer fills an inner portion of the isolation trench. The insulation layer liner is partially removed to expose an upper surface of the substrate in the gate region of the first region, and an upper surface and sidewalls of the substrate in the gate region of the second region. A gate oxide layer and a gate electrode are formed on the exposed substrate.
US07816227B2 Tapered through-silicon via structure
An integrated circuit structure includes a substrate; a through-silicon via (TSV) in the substrate, the TSV being tapered; a hard mask region extending from a top surface of the substrate into the substrate, wherein the hard mask encircles a top portion of the TSV; dielectric layers over the substrate; and a metal post extending from a top surface of the dielectric layers to the TSV, wherein the metal post comprises same materials as the TSV.
US07816224B2 Method for fabricating an ultra thin silicon on insulator
In one embodiment, the invention is a method for fabricating an ultra thin silicon on insulator. One embodiment of a method for fabricating an ultra thin silicon on insulator includes providing a silicon layer, saturating the silicon layer with at least one reactant gas at a first temperature, the first temperature being low enough to substantially prevent the occurrence of any reactions involving the reactant gas, and raising the first temperature to a second temperature, the second temperature being approximately a dissociation temperature of the reactant gas.
US07816211B2 Method of making a semiconductor device having high voltage transistors, non-volatile memory transistors, and logic transistors
A semiconductor device is made on a semiconductor substrate. A first insulating layer is formed on the semiconductor substrate for use as a gate dielectric for a high voltage transistor in a first region of the semiconductor substrate. After the first insulating layer is formed, a second insulating layer is formed on the semiconductor substrate for use as a gate dielectric for a non-volatile memory transistor in a second region of the substrate. After the second insulating layer is formed, a third insulating layer is formed on the semiconductor substrate for use as a gate dielectric for a logic transistor in a third region of the substrate.
US07816209B2 Method for fabricating semiconductor device
A method for fabricating a semiconductor device includes forming an insulation layer over a substrate including a pattern for forming a multi-plane channel, forming a columnar polysilicon layer over the insulation layer and filling in the pattern, and performing a thermal treatment process.
US07816207B2 Semiconductor device having electrode and manufacturing method thereof
A manufacturing method of a semiconductor device includes a first electrode formation step of forming a control gate electrode above a surface of a semiconductor substrate with a control gate insulating film interposed between the control gate electrode and the semiconductor substrate, a step of forming a storage node insulating film on the surface of the semiconductor substrate, and a second electrode formation step of forming a memory gate electrode on a surface of the storage node insulating film. The second electrode formation step includes a step of forming a memory gate electrode layer on the surface of the storage node insulating film, a step of forming an auxiliary film, having an etching rate slower than that of the memory gate electrode layer, on a surface of the memory gate electrode layer, and a step of performing anisotropic etching on the memory gate electrode layer and the auxiliary film.
US07816205B2 Method of forming non-volatile memory having charge trap layer with compositional gradient
A flash memory device and method of forming a flash memory device are provided. The flash memory device includes a silicon nitride layer having a compositional gradient in which the ratio of silicon to nitrogen varies through the thickness of the layer. The silicon nitride layer having a compositional gradient of silicon and nitrogen provides an increase in charge holding capacity and charge retention time of the unit cell of a non-volatile memory device.
US07816204B2 Semiconductor device comprising capacitor and method of fabricating the same
A semiconductor device, having a memory cell region and a peripheral circuit region, includes an insulating film, having an upper surface, formed on a major surface of a semiconductor substrate to extend from the memory cell region to the peripheral circuit region. A capacitor lower electrode assembly is formed in the memory cell region to upwardly extend to substantially the same height as the upper surface of the insulating film on the major surface of the semiconductor substrate. Additionally, the lower electrode assembly includes first and second lower electrodes that are adjacent through the insulating film. A capacitor upper electrode is formed on the capacitor lower electrode through a dielectric film, to extend onto the upper surface of the insulating film. The capacitor lower electrode includes a capacitor lower electrode part having a top surface and a bottom surface. A semiconductor device organized as just described, permits implementation having a high density of integration while ensuring the capacitor exhibits high reliability and a constant capacitance.
US07816203B1 Method for fabricating a semiconductor device
A method is provided for fabricating a semiconductor device having a gate electrode overlying a gate insulator. The method, in accordance with one embodiment, comprises depositing a layer of spin on glass overlying the gate electrode, the layer of spin on glass comprising a substantially UV opaque material. The layer of spin on glass is heated to a temperature less than about 450° C., and all subsequent process steps in the fabrication of the device are limited to temperatures less than about 450° C.
US07816202B2 Method for fabricating capacitor in semiconductor device
A method for fabricating a capacitor includes providing a substrate having a capacitor region is employed, forming a first Ru1−xOx layer over the substrate, forming a Ru layer for a lower electrode over the first Ru1−xOx layer and deoxidizing the first Ru1−xOx layer, forming a dielectric layer over the Ru layer for a lower electrode, and forming a conductive layer for an upper electrode over the dielectric layer, wherein the first Ru1−xOx layer contains oxygen in an amount less than an oxygen amount of a RuO2 layer.
US07816194B2 Method of manufacturing thin film transistor
A method of manufacturing thin film transistor is provided, in which the method of manufacturing includes a new etching process of island semiconductor. The new etching process of island semiconductor is controlled by a flow rate of etching gas and a regulation of etching power. When etching the island semiconductor, a part of gate insulation layer exposed out of the island semiconductor is etched at the same time. Consequently, the thickness of gate insulation layer over the storage capacitance electrode is reduced, the distance between the pixel electrode and the storage capacitance electrode is decreased, and the storage capacitance of pixel is increased. Finally, the width of storage capacitance electrode is reduced appropriately and the aperture ratio of product is increased.
US07816187B2 Method for fabricating semiconductor package free of substrate
A semiconductor package and a fabrication method thereof are provided in which a dielectric material layer formed with a plurality of openings is used and a solder material is applied into each of the openings. A first copper layer and a second copper layer are in turn deposited over the dielectric material layer and solder materials, and the first and second copper layers are patterned to form a plurality of conductive traces each of which has a terminal coated with a metal layer. A chip is mounted on the conductive traces and electrically connected to the terminals by bonding wires, with the dielectric material layer and solder materials being exposed to the outside. This package structure can flexibly arrange the conductive traces and effectively shorten the bonding wires, thereby improve trace routability and quality of electrical connection for the semiconductor package.
US07816186B2 Method for making QFN package with power and ground rings
A method to manufacture a package that encases at least one integrated circuit device and the package so manufactured. The method includes the steps of (1) providing a leadframe having a die pad, leads, at least one ring circumscribing the die pad and disposed between the die pad and the leads, a plurality of tie bars projecting outwardly from the at least one ring, and at least one connecting bar electrically interconnecting and mechanically supporting the die pad to the ring; (2) affixing the at least one integrated circuit device to a first side of the die pad and electrically interconnecting the at least one integrated circuit device to the leads and to the at least one ring; (3) encapsulating the at least one integrated circuit device, the first side of the die pad and a first side of the ring in a molding resin while retaining an opposing second side of the ring external to said molding resin; and (4) severing the at least one connecting bar to electrically isolate the die pad from the ring.
US07816185B2 Method of manufacturing a semiconductor device
A semiconductor device manufacturing method comprising the steps of providing a matrix substrate having a main surface with plural device areas formed thereon, fixing plural semiconductor chips to the plural device areas respectively, then sealing the plural semiconductor chips all together with resin to form a block sealing member, dividing the block sealing member and the matrix substrate for each of the device areas by dicing, thereafter rubbing a surface of each of the diced sealing member portions with a brush, then storing semiconductor devices formed by the dicing once into pockets respectively of a tray, and conveying the semiconductor devices each individually from the tray. Since the substrate dividing work after block molding is performed by dicing while vacuum-chucking the surface of the block sealing member, the substrate division can be done without imposing any stress on an external terminal mounting surface of the matrix substrate.
US07816184B2 Micromachine device processing method
A micromachine device processing method for dividing a functional wafer, which has micromachine devices formed in a plurality of regions demarcated by streets formed in a lattice pattern on a face of the functional wafer, along the streets into the individual micromachine devices, each micromachine device having a moving portion and an electrode, comprising: a cap wafer groove forming step of forming dividing grooves, which have a depth corresponding to a finished thickness of a cap wafer for protecting the face of the functional wafer, along regions in one surface of the cap wafer which correspond to areas of the electrodes of the micromachine devices; a cap wafer joining step of joining the one surface of the cap wafer subjected to the cap wafer groove forming step to the face of the functional wafer at peripheries of the moving portions; a cap wafer grinding step of grinding the other surface of the cap wafer joined to the face of the functional wafer to expose the dividing grooves to the outside; and a cutting step of cutting the functional wafer and the cap wafer subjected to the cap wafer grinding step along the streets.
US07816183B2 Method of making a multi-layered semiconductor device
In the multiple-layered semiconductor device and the method for manufacturing thereof according to the present invention, the resin is formed on the substrate around the semiconductor device, on which the semiconductor device is installed in the first semiconductor package. Therefore, a generation of a warpage of substrate is inhibited in the first semiconductor package. And since the first semiconductor package is stacked to and coupled to the second semiconductor package via the electric conductors that extend from the back surface of the second semiconductor package to the coupling lands on the substrate penetrating through the resin, a defective situation such as a coupling defective in the bump junction can be avoided when the junction of the second semiconductor package via the electric conductor is formed. Therefore, a considerably improved coupling reliability in the multiple-layered semiconductor device can be achieved.
US07816180B2 Method for processing a base that includes connecting a first base to a second base
The present invention realizes a semiconductor device of high reliability which allows metal terminals which have a uniform height, are flat and smooth to be formed under low load and at low costs and to be mounted with low damage. The electrodes 5 and the insulating film 6 are both formed of materials having the property that they are solid and do not exhibit the adhesiveness at room temperature and exhibit the adhesiveness at a temperature not lower than a first temperature and cure at a temperature not lower than a second temperature higher than the first temperature. The surfaces of the electrodes 5 and the insulating film 6 of a semiconductor chip 1a are planarized in continuously flat with a hard cutting tool, as of diamond or others.
US07816178B2 Packaged semiconductor device with dual exposed surfaces and method of manufacturing
The invention claimed is a packaged semiconductor device with dual exposed surfaces and a method of manufacturing the device. A thermal clip and one or multiple source pads are exposed on opposite ends of the device through a nonconductive molding material used to package the device. The thermal clip and source pad can be either top or bottom-exposed. The gate, source and drain leads are exposed through the molding material, and all leads are coplanar with the bottom-exposed surface. The device can have multiple semiconductor dies or various sized dies while still having a single, constant footprint. The method of manufacturing requires attaching the semiconductor die to a thermal clip, and then attaching the die with the attached thermal clip to a lead frame. The resulting device is then molded, marked, trimmed and singulated, in this order, creating a packaged semiconductor device with dual exposed surfaces.
US07816176B2 Method of manufacturing electronic component package
In a method of manufacturing an electronic component package, first, a plurality of sets of external connecting terminals corresponding to a plurality of electronic component packages are formed by plating on a top surface of a substrate to thereby fabricate a wafer. The wafer includes a plurality of pre-base portions that will be separated from one another later to become bases of the respective electronic component packages. Next, at least one electronic component chip is bonded to each of the pre-base portions of the wafer. Next, electrodes of the electronic component chip are connected to the external connecting terminals. Next, the electronic component chip is sealed. Next, the wafer is cut so that the pre-base portions are separated from one another and the plurality of bases are thereby formed.
US07816170B2 Dual-pixel full color CMOS imager with large capacity well
A dual-pixel full color CMOS imager comprises a two-photodiode stack including an n doped substrate, a bottom photodiode, and a top photodiode. The bottom photodiode has a bottom p doped layer at a first depth overlying the substrate and a bottom n doped layer cathode overlying the bottom p doped layer. The top photodiode has a top p doped layer overlying the bottom n doped layer and a top n doped layer cathode overlying the top p doped layer. A single photodiode including a bottom p doped layer overlies the substrate at a third depth. The third depth is less than, or equal to the first depth. A bottom n doped layer overlies the bottom p doped layer, a top p doped layer directly overlies the bottom n doped layer without an intervening layer, and a top n doped layer overlies the top p doped layer.
US07816169B2 Colors only process to reduce package yield loss
Disclosed is an ordered microelectronic fabrication sequence in which color filters are formed by conformal deposition directly onto a photodetector array of a CCD, CID, or CMOS imaging device to create a concave-up pixel surface, and, overlayed with a high transmittance planarizing film of specified index of refraction and physical properties which optimize light collection to the photodiode without additional conventional microlenses. The optically flat top surface serves to encapsulate and protect the imager from chemical and thermal cleaning treatment damage, minimizes topographical underlayer variations which would aberrate or cause reflection losses of images formed on non-planar surfaces, and, obviates residual particle inclusions induced during dicing and packaging. A CCD imager is formed by photolithographically patterning a planar-array of photodiodes on a semiconductor substrate. The photodiode array is provided with metal photoshields, passivated, and, color filters are formed thereon. A transparent encapsulant is deposited to planarize the color filter layer and completes the solid-state color image-forming device without conventional convex microlenses.
US07816168B2 Method for forming color filter
A method for forming a color filter is provided. A substrate having a passivation layer thereon is provided. The passivation layer has at least one trench therein within a peripheral region of the substrate. A first color filter layer is formed over the passivation layer to fill the trench by performing a first spin-on coating process with a first spin rate. Thereafter, the first color filter layer is patterned so as to form a plurality of first color filter blocks in a display region of the substrate and expose a portion of the passivation layer. A second color filter layer is formed over the passivation layer by performing a second spin-on coating process with a second spin rate, which is larger than the first spin rate. Next, the second color filter layer is patterned to form a plurality of second color filter blocks between the first color filter blocks respectively.
US07816162B2 Semiconductor device manufacturing method
After a p-type cladding layer, an etching rate reducing layer and a p-type contact layer are formed in order on an n-type substrate, an etching mask is formed. Then, by using the etching mask, the p-type contact layer, the etching rate reducing layer and the p-type cladding layer are partially etched in the region outside the etching mask with an etchant. At this time, the etching rate of the layers by the etchant is slower in the etching rate reducing layer than in the p-type cladding layer and the p-type contact layer. Then, a metal thin film is formed such that the film continuously coats an upper surface and side surfaces of a ridge consisting of the above layers left after the etching step. A normal vector at a surface coated with the thin film has an upward component.
US07816160B2 Manufacturing method for semiconductor device
The present invention includes forming an optical guide layer on a substrate, forming a cap layer on the optical guide layer, and forming openings in parts of the optical guide layer and the cap layer to form a diffraction grating from part of the optical guide layer. The substrate is heated to a temperature less than a growth temperature of the cap layer and equal to at least a temperature at which mass transport of the cap layer occurs to cover, with part of the cap layer, the lateral faces of the optical guide layer exposed by the openings. A burying layer burying the diffraction grating is formed on the substrate, after the mass transport.
US07816159B2 Method for fabricating pixel structure
A method for fabricating a pixel structure includes following steps. First, a substrate is provided. Next, a first conductive layer is formed on the substrate. Next, a first shadow mask is disposed over the first conductive layer. Next, a laser is applied through the first shadow mask to irradiate the first conductive layer to form a gate. Next, a gate dielectric layer is formed on the substrate to cover the gate. After that, a channel layer, a source and a drain are simultaneously formed on the gate dielectric layer over the gate, wherein the gate, the channel layer, the source and the drain together form a thin film transistor. A patterned passivation layer is formed on the thin film transistor and the patterned passivation layer exposes a part of the drain. Furthermore, a pixel electrode electrically connecting to the drain is formed.
US07816158B2 Liquid crystal display device and method for manufacturing the same
The present invention provides a liquid crystal display device to be operated at high speed and with high precision by improving performance of a thin-film transistor without increasing cross capacity of gate lines and data lines. On an upper layer of a gate insulator GI at an intersection of gate lines GL and data lines DL to be prepared on an active matrix substrate SUB1, which makes up a liquid crystal display panel of a liquid crystal display device, an insulating material with low dielectric constant is dropped by ink jet coating method to prepare another insulator LDP in order to improve performance characteristics of the thin-film transistor to be prepared on a silicon semiconductor layer SI without increasing cross capacity on said intersection.
US07816157B2 Method of producing semiconductor optical device
The invention discloses a method of producing on a substrate a semiconductor optical device having a laser diode and an EA optical modulator. An etched side face of a first semiconductor portion is formed. Then, for example, a first optical confinement layer and an active layer both for the EA optical modulator are grown by the metal organic vapor phase epitaxy method. The first optical confinement layer is grown by supplying hydrogen chloride in addition to a material gas. When the first optical confinement layer is grown, the formation of a thick semiconductor layer along the etched side face, which is an abnormally grown semiconductor layer, is decreased. Subsequently, the active layer for the EA optical modulator is grown. This method can suppress the active layer for the EA optical modulator from bending caused by the abnormally grown semiconductor layer.
US07816156B2 Light emitting diode package and fabrication method thereof
The present invention provides a light emitting diode (LED) package and the fabrication method thereof. The LED package includes a lower metal layer, and a first silicon layer, a first insulation layer, a second silicon layer, a second insulation layer, and a package electrode pattern formed in their order on the lower metal layer. The LED package also includes a spacer having a cavity, formed on the electrode pattern. The LED package further includes an LED mounted in the cavity by flip-chip bonding to the electrode patterns, and an optical element attached to the upper surface of the spacer.
US07816148B2 Open-field serial to parallel converter
Microfluidic devices and systems for affecting the serial to parallel conversion of materials introduced into the device or system. Material or materials to be converted from a serial orientation, e.g., a single channel, into a parallel orientation, e.g., multiple channels, are introduced into an open chamber or field in which containing flows of materials maintain the cohesiveness of the sample material plugs serially introduced into the open chamber. The sample material or materials are then redirected in the chamber toward and into a plurality of parallel channels that also communicate with the chamber.
US07816140B2 Composition and methods for osteogenic gene therapy
The present disclosure provides compositions and methods for increasing bone growth and/or enhancing wound healing, for example, fracture repair. The disclosure provides recombinant nucleic acids useful for promoting bone growth. For example, the disclosure provides recombinant nucleic acids that encode a fibroblast growth factor-2 (FGF-2) analog. The disclosure also provides vectors and cells incorporating these nucleic acids, as well as FGF-2 analogs encode by them. The disclosure also provides a mouse system of bone marrow transplantation and methods for producing as well as methods for using the system. Methods for inducing division and/or inducing differentiation of a hematopoietic stem cell are also provided, as are methods for enhancing bone growth and/or wound repair (for example, fracture repair).
US07816135B2 Method of analyzing lymphocytes
The invention provides methods and compositions for identifying and counting lymphocytes in a biological sample, such as whole blood, by means of a probe comprising at least one binding compound specific for a T lymphocyte-specific marker, e.g. a CD2 or CD3, and at least one binding compound specific for CD45RA. Lymphocytes within the sample combine with such a probe to form a distinguishable subpopulation based on the amount of probe that specifically binds to their surfaces, thereby permitting such lymphocytes to be detected and enumerated on the basis of the intensity of the signal generated by the probe, and without the need of a separate physical measurement, such as light scatter. With additional probes specific for additional blood cell markers, percentages of lymphocytes, monocytes and granulocytes in a sample may be determined.
US07816133B2 Preparation of fibroblast-populated connective tissue substitute
Disclosed is a method for in vitro growing of connective tissue substitute, said connective tissue substitute being populated with fibroblasts, a connective tissue substitute obtainable by such a method, as well as a method for closing of a wound, wherein such connective tissue substitute is applied onto a wound.
US07816128B2 Automatic cell cultivation apparatus having a multijoint robot
An automatic cell cultivation apparatus is provided which is capable of conveying the culture container, exchanging the culture medium, and operating other jobs promptly by a robot. The automatic cell cultivation apparatus has a cultivation apparatus main body for cultivating cells in a culture container, and the cultivation apparatus main body is equipped with one or more incubator accommodating the culture container, a chemical suction machine for sucking chemicals in the culture container, and a multijoint robot for conveying the culture container, the multijoint robot having functions of conveying the culture container, detaching and attaching the lid of the culture container, and inclining the container when sucking chemicals in the culture container, so that cell cultivation operations can be promptly carried out by only one robot.
US07816123B2 Methods and apparatuses for achieving precision genetic diagnoses
Methods and apparatuses for selecting and arranging clinically relevant chromosomal loci allow an exemplary diagnostic array to simultaneously test for numerous genetic alterations that occur in many different parts of the human genome. Clinically irrelevant or ineffective loci are eliminated. One implementation increases reliability and accuracy by dividing the base-pair sequence of each chromosomal locus into segments and then assigning nucleic acid clones for comparative genomic hybridization to each different segment. The segments may overlap for increased resolution and control. Clones representing segments that are adjacent on a native chromosome are placed in non-adjacent target areas of the array to avoid interfering hybridization reactions. Arrangement motifs within an array may be redundantly repeated for high availability and increased reliability and accuracy of results. Techniques, hardware, software, logic engines, loci collections, and diagnostic arrays are described.
US07816121B2 Droplet actuation system and method
A droplet actuation system is provided including a droplet actuation device including a substrate that includes electrodes for conducting droplet operations; temperature control means for heating and/or cooling a region of the droplet actuation device and arranged such that a droplet can be transported on the electrodes to a region for heating; and a means for effecting a magnetic field in proximity to one or more of the electrodes sufficient to immobilize magnetically responsive beads in a droplet on the substrate during droplet operations. The system further includes a processor for controlling the electrodes and temperature control means, wherein the processor is programmed, and electrodes and magnetic field are arranged, to cause the electrodes to split a droplet including the magnetically responsive beads yielding a first daughter droplet which includes the magnetically responsive beads and a second daughter droplet without a substantial amount of the magnetically responsive beads.
US07816119B2 Chemoenzymatic process for the stereoselective preparation of (R)-γ-amino-β-hydroxybutyric acid or (R)-carnitine from 3,4-dihydroxybutanenitrile
The present invention provides a chemoenzymatic process for the preparation of (R)-GABOB and (R)-carnitine employing lipase-mediated resolution of 3-hydroxy-4-tosyloxybutanenitrile as the key step. The drawing accompanying this specification represents the preparation of racemic 3-hydroxy-4-tosyloxybutanenitrile, its lipase-mediated kinetic resolution and its successful application in the preparation of (R)-GABOB and (R)-carnitine.
US07816117B2 Prokaryotic host cells for expressing proteins rich in disulfide bonds
The invention provides composition and methods for producing proteins of interest which comprise at least one disulfide bond, include proteins which in their mature form do not contain disulfide bonds, but whose precursor molecule contained at least one disulfide bond. The methods employ a host cell modified to more efficiently produce properly folded disulfide bond containing proteins. The host cells generally contain a mutation in one or more reductase genes, and can be further genetically modified to increase their growth rate, and are further optionally modified to increase the expression of a catalyst of disulfide bond formation. Host cells, methods for u sing such to produce proteins of interest, proteins of interest produced by these methods are within the scope of the invention.
US07816115B2 Subtilases
The present invention relates to novel JP170 like subtilases from wild-type bacteria, hybrids thereof and to methods of construction and production of these proteases. Further, the present invention relates to use of the claimed subtilases in detergents, such as a laundry or an automatic dishwashing detergent.
US07816114B2 Methods of using crystals of beta amyloid cleaving enzyme (BACE)
Methods of using monoclinic crystals of human beta-secretase (BACE) having unit cell dimensions of a, b, and c, wherein a is about 81±20 Å to about 101 Å, b is 103±20 Å, c is 100±20 Å, and α=γ=90°, and β is 105°±10° for crystals of symmetry P21 and a=73.1, b=105.1, c=50.5 Å and β is 94.8° for crystals of C2 symmetry in drug screening assays comprising selecting a potential modifier by adding the potential modifiers to an aqueous mixture of the crystal and detecting a measure of binding, such that the potential modifier that binds is selected as a potential drug.
US07816112B2 Castable diffusion membrane for enzyme-based sensor application
The invention relates to a diffusion membrane for an enzyme-based sensor, a sensor comprising the diffusion membrane as well as the use of the enzyme-based sensor for the detection and/or determination of a substance, in particular an enzyme substrate, e.g., glucose.
US07816111B2 Glucose dehydrogenase polypeptides and related polynucleotides
The present invention is directed to glucose dehydrogenase (GDH) polypeptides that have enhanced GDH activity and/or thermostability relative to the backbone wild-type glucose dehydrogenase polypeptide. In addition, the present invention is directed to a polynucleotide that encodes for the GDH polypeptides of the present invention, to nucleic acid sequences comprising the polynucleotides, to expression vectors comprising the polynucleotides operatively linked to a promoter, to host cells transformed to express the GDH polypeptides, and to a method for producing the GDH polypeptides of the present invention.
US07816109B2 Microorganism having the improved gene for hydrogen-generating capability, and process for producing hydrogen using the same
A hydrogen producing method by culturing a microorganism having a hydrogenase gene, in which a lactic acid biogenetic path and a succinic acid biogenetic path in anaerobic metabolic paths are inactivated, under an anaerobic condition in the presence of organic substrate. The microorganism may further have a formate dehydrogenase gene. The microorganism may be Escherichia coli which is a facultative anaerobic bacterium.
US07816104B2 Packaging cells for recombinant adenovirus
In the absence of substantial sequence overlap between a recombinant adenoviral vector and the genome of a packaging cell, helper-dependent E1-containing particles (HDEP) can be formed at low frequency. The invention provides means and methods reducing or preventing the generation of HDEP. To this purpose, novel packaging cells and methods of making these are provided.
US07816099B1 Enzyme assay and use thereof
An assay and kit for determining the activity of an enzyme such as kinase, ATPase and GTPase is disclosed. The assay and kit are useful in drug screening to select modulators of such an enzyme.
US07816098B2 Methods of making and using a protein array
The present invention describes methods for the preparation of protein arrays of full length proteins. The use of such arrays in screening methods is also described.
US07816089B2 Methods for diagnosing and treating pediatric neoplasms
The present invention provides a method for determining whether a subject has a pediatric neoplasm. The present invention further provides a method for assessing the efficacy of therapy to treat a pediatric neoplasm in a subject who has undergone or is undergoing treatment for a pediatric neoplasm. In addition, the present invention provides a method for assessing the prognosis of a subject who has a pediatric neoplasm. Finally, the present invention provides a method for treating a pediatric neoplasm in a subject in need of treatment thereof.
US07816086B2 Genes of an otitis media isolate of nontypeable Haemophilus influenzae
The invention relates to the polynucleotide sequence of a nontypeable stain of Haemophilus influenzae (NTHi) and polypeptides encoded by the polynucleotides and uses thereof. The invention also relates to NTHi genes which are upregulated during or in response to NTHi infection of the middle ear and/or the nasopharynx.
US07816083B2 Genetic polymorphisms associated with neurodegenerative diseases, methods of detection and uses thereof
The present invention is based on the discovery of genetic polymorphisms that are associated with neurodegenerative disease, particularly Alzheimer's disease and Parkinson's disease. In particular, the present invention relates to nucleic acid molecules containing the polymorphisms, variant proteins encoded by such nucleic acid molecules, reagents for detecting the polymorphic nucleic acid molecules and proteins, and methods of using the nucleic acid and proteins as well as methods of using reagents for their detection.
US07816082B2 Methods of identifying pancreatic cancer cells
Methods that identify cells as pancreatic cancer cells based on assessing the expression of combinations of target molecules expressed preferentially on pancreatic cancer cells are disclosed. Combinations were initially discovered by microarray analysis and selected based upon tumor specificity, relative lack of cross-reactivity with normal tissues, and applicability as targets of multispecific ligands. The claimed methods encompass measuring the expression of three or more specific target molecules in combination and correlating positive expression of the combination with an identification of the cell as a pancreatic cancer cell.
US07816080B2 Identifying organisms by detecting intronic nucleic acid or encoded proteins
The present invention provides novel methods for characterizing organisms by identifying the presence, absence, size or sequence polymorphism of intronic regions. The method involves selecting intronic regions from nuclear or organellar gene sequences that are useful for differentiating between and among taxonomic groupings of organisms. Such intronic regions can be analyzed directly or after amplification in a primer extension reaction. The amplification product is then analyzed by, for example, size fractionation, nucleotide sequencing or (RFLP). Intronic regions that contain an open reading frame encoding all or a portion of a protein can be used to generate antibodies to detect the presence or absence of the protein, which indicates the presence or absence of the intronic region. Methods of detecting an organism in a sample by detecting the presence or absence of one or more intronic regions also are provided using nucleic acid based or immunological based approaches. Kits are provided for practicing the methods of the invention.
US07816078B2 Method for identifying biological species
The present invention provides a method for identifying species and subspecies in a biological sample through the selective amplification of segments of nucleic acid that code a target region of the cytoplasmatic beta-actin protein, which is present in all the organisms concerned. The method comprises DNA extraction from the sample; amplification of divergent segments of the cytoplasmatic beta-actin gene by PCR or an equivalent technique, using primers of regions with high evolutionary conservation between species and subspecies; and identification of the amplified segment by comparison of its size in base pairs with a pre-established standard of sizes and/or identification of the amplified segment by DNA sequencing and comparison of the resulting sequence with the specific sequence of each species or subspecies present on a computer database.
US07816076B2 Therapeutic targets in cancer
The present invention relates to novel sequences for use in detection, diagnosis and treatment of cancers, especially lymphomas. The invention provides cancer-associated (CA) polynucleotide sequences whose expression is associated with cancer. The present invention provides CA polypeptides associated with cancer that are present on the cell surface and present novel therapeutic targets against cancer. The present invention further provides diagnostic compositions and methods for the detection of cancer. The present invention provides monoclonal and polyclonal antibodies specific for the CA polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of cancer.
US07816070B2 Substrate used for immersion lithography process, method of manufacturing substrate used for immersion lithography process, and immersion lithography
A substrate having a photoresist film, capable of easily performing immersion lithography with high precision and stability, is provided. A surface tension of the substrate in a periphery region is lower than that of the substrate in a rest region. Immersion liquid supplied onto the photoresist film hardly leaks out, and the bubbles hardly occur in the immersion liquid.
US07816069B2 Graded spin-on organic antireflective coating for photolithography
An antireflective coating that contains at least two polymer components and comprises chromophore moieties and transparent moieties is provided. The antireflective coating is useful for providing a single-layer composite graded antireflective coating formed beneath a photoresist layer.
US07816068B2 Underlayer compositions containing heterocyclic aromatic structures
A composition suitable for use as a planarizing underlayer in a multilayer lithographic process is disclosed. The inventive composition comprises a polymer containing heterocyclic aromatic moieties. In another aspect, the composition further comprises an acid generator. In yet another aspect, the composition further comprises a crosslinker. The inventive compositions provide planarizing underlayers having outstanding optical, mechanical and etch selectivity properties. The present invention also encompasses lithographic structures containing the underlayers prepared from the compositions of the present invention, methods of making such lithographic structures, and methods of using such lithographic structures to pattern underlying material layers on a substrate.
US07816066B2 Positive resist composition and method for forming resist pattern
A positive resist composition includes a resin component (A), and an acid generator component (B) which generates an acid upon exposure and includes an acid generator (B1) represented by general formula (B1): (wherein R51 represents a straight chain, branched chain, or cyclic alkyl group, or a straight chain, branched chain, or cyclic fluorinated alkyl group; R52 represents a hydrogen atom, a hydroxyl group, a halogen atom, a straight chain, branched chain, or cyclic alkyl group, a straight chain or branched chain halogenated alkyl group, or a straight chain or branched chain alkoxy group; R53 represents an aryl group which may include a substituent; and n represents an integer from 1 to 3).
US07816065B2 Imageable printing plate for on-press development
A novel coating for lithographic printing plates can be imagewise exposed to radiation and then directly processed with only water to remove the non-exposed regions of the coating. The coating comprises a polymer, a monomer and/or oligomer, polymerization or cross link initiator, stabilizer, and dye or pigment, such that after imaging, the non-imaged resin areas are removable from the planar surface by penetration of water through the non-imaged coating without dissolution of the resin components of the coating, to form a lithographic printing plate with clearly defined image and non-image areas. The stabilizer is a solvent soluble, partially water soluble, non-polymerizable organic component that enables the coating to be removable by water in the non-cross linked areas.
US07816063B2 Color toner and two-component developer
The present invention relates to a toner which has good property such as fixability, coloring power, developability, durability, and environmental stability and so on. More specifically, the present invention relates to a color toner containing at least a binder resin, a colorant, and a wax, in which: a wax concentration of an extract obtained by dispersing the toner into n-hexane at a concentration of 15 mg/cm3 at 23° C. and by subjecting the resultant dispersion to extraction treatment at 23° C. for 1 minute is in the range of 0.080 to 0.500 mg/cm3; an average circularity of particles each having a circle-equivalent diameter of 3 μm or more in the toner is in the range of 0.925 to 0.965; and a content of the wax is in the range of 1 to 15 parts by mass with respect to 100 parts by mass of the binder resin.
US07816060B2 Manufacturing method of semiconductor device, reticle correcting method, and reticle pattern data correcting method
A manufacturing method of a semiconductor device including a pattern forming method, a reticle correcting method, and a reticle pattern data correcting method are disclosed. According to one aspect of the present invention, there is provided a manufacturing method of a semiconductor device, comprising forming a pattern composed of photosensitive resin film including forming periodically arranged first contact hole patterns of a first photosensitive resin film on a processing film formed above a semiconductor substrate, and forming a selective opening pattern of a second photosensitive resin film including various opening pattern types on the first photosensitive resin film, whereby selectively forming second contact hole patterns at positions of the first contact hole patterns selected by the selective opening patterns, wherein the first contact hole patterns have corrected dimensions such that dimensions of the second contact hole patterns become equivalent each other independent of the opening pattern types.
US07816058B2 Split architectures for MEA durability
A membrane electrode assembly including an ionically conductive member, an electrode, and an electrically conductive member including an active layer, wherein the electrode is a smooth, continuous layer that completely covers and supports the ionically conductive member. The electrode and active layer further include a first and second catalyst content, respectively; and 50% of the total catalyst content is present in the electrode and 50% of the total catalyst content is present in the active layer.
US07816057B2 Fuel supply method for direct methanol fuel cell
In a direct methanol fuel cell, fuel efficiency is maintained by periodically adding a higher methanol concentration mixture through a cartridge into the primary fuel container. The cartridge replenishes methanol and partial water losses due to the consumption of fuel in the power generating process. In a typical system, the fuel replenishment mechanism is controlled through an electronic apparatus that monitors the power conversion process and is capable of predicting remaining operating capacity.
US07816056B2 Structure of fuel cell assembly
A structure of fuel cell assembly is disclosed. A flow channel plate with a plurality of flow fields is respectively disposed on two sides of a fuel cell unit. A plurality of graphic electrodes is arranged on two sides of the fuel cell unit and the flow field matches the graphic electrodes. Thus water generated from reaction of the fuel cell is removed and further reduction of the performance of the fuel cell is avoided. Moreover, fuel is distributed more uniformly over reaction area of the cell. And the number of fuel cells stacked per unit volume is increased. Therefore, the efficiency of the fuel cell is improved.
US07816055B2 Compact fuel cell
A novel electrochemical cell which may be a solid oxide fuel cell (SOFC) is disclosed where the cathodes (144, 140) may be exposed to the air and open to the ambient atmosphere without further housing. Current collector (145) extends through a first cathode on one side of a unit and over the unit through the cathode on the other side of the unit and is in electrical contact via lead (146) with housing unit (122 and 124). Electrical insulator (170) prevents electrical contact between two units. Fuel inlet manifold (134) allows fuel to communicate with internal space (138) between the anodes (154 and 156). Electrically insulating members (164 and 166) prevent the current collector from being in electrical contact with the anode.
US07816049B2 Direct liquid feed fuel cell
A direct liquid feed fuel cell includes a membrane electrode assembly (MEA) including an anode electrode and a cathode electrode respectively disposed on either side of an electrolyte membrane. A conductive anode plate and a conductive cathode plate which respectively face the anode electrode and the cathode electrode, and have flow channels therein. Stripe-shaped hydrophilic members are formed on the cathode electrode, cross the flow channels of the conductive cathode plate, and transfer water from the flow channels to the conductive cathode plate. The conductive cathode plate is hydrophilic.
US07816047B2 Method for stopping power generation of fuel cell system and fuel cell system including power generation stopping unit
There is provided a method for stopping power generation of fuel cell system including: a fuel cell having a fuel electrode and an oxidizer electrode; a fuel container; and a fuel flow path for supplying a fuel from the fuel container to the fuel cell, which enables suppression of a pressure difference between the fuel electrode and the oxidizer electrode during a stop state of an operation of the fuel cell, the method including the steps of, during the stop state of the operation of the fuel cell: stopping supply of the fuel from the fuel container to the fuel cell; consuming a residual fuel in the fuel flow path by short-circuiting the fuel electrode and the oxidizer electrode or connecting a load between the fuel electrode and the oxidizer electrode; and opening the fuel flow path to the atmosphere.
US07816045B2 Fuel cell system and control method therefor
A fuel cell system including a fuel cell stack is capable of raising the temperature of a fuel cell stack to a predetermined temperature within a short time without decreasing methanol fuel utilization efficiency. During system startup, the concentration of methanol aqueous solution which is to be supplied to the fuel cell stack is detected by a concentration sensor, and the temperature of the fuel cell stack is detected by a temperature sensor. A target concentration of methanol aqueous solution is determined by making reference to data stored in a memory, which indicates correspondence between the temperature of the fuel cell stack and the target concentration of methanol aqueous solution, and based on the temperature of the fuel cell stack detected by the temperature sensor.
US07816044B1 Fuel cell using a hydrogen generation system
A system is described for storing and generating hydrogen and, in particular, a system for storing and generating hydrogen for use in an H2/O2 fuel cell. The hydrogen storage system uses beta particles from a beta particle emitting material to degrade an organic polymer material to release substantially pure hydrogen. In a preferred embodiment of the invention, beta particles from 63Ni are used to release hydrogen from linear polyethylene.
US07816037B2 Anode material for lithium ion secondary battery
The invention provides an anode material for lithium ion secondary battery using a coated graphite powder as a raw material, which is coated thermoplastic resin of a carbonization yield of ≦20 wt % in a proportion of ≦10 parts by weight the carbonized material per 100 parts by weight graphite powder. Coating with thermoplastic resin increases the accumulative pore volume by ≦5%, relative to the uncoated powder, and results in pore sizes of 0.012-40 μm via mercury porosimeter method. Calculated with the BJH method as viewed from desorption isotherm, the coated graphite powder has a mesopore volume ≦0.01 cc/g or ≦60% of the pore volume of the uncoated graphite powder. This coated powder also has an average particle size ranging from 10-50 μm measured by a laser-scattering-particle-size-distribution measuring device, and a standard deviation to the average particle size (σ/D) ratio of ≦0.02.
US07816036B2 Positive electrode active material and non-aqueous electrolyte secondary cell comprising the same
To provide a non-aqueous electrolyte secondary battery in which the amount of Li deposited is small and the battery surface temperature does not increase so much, a positive electrode active material comprising crystal particles of an oxide having a layered single-phase crystal structure and a composition represented by the formula (1): LiNi2/3Mn1/3O2, wherein the arrangement of oxygen atoms constituting the oxide is a cubic close-packed structure is used.
US07816035B2 Methods for production of zinc oxide electrodes for alkaline batteries
A zinc electrode for use in alkaline batteries comprises a mixture of 0.425 to 1.55 volume parts of zinc oxide with a volume part of a metallic oxide chosen from the group consisting of: calcium oxide, barium oxide, and mixtures thereof, together with hydroxy-ethyl cellulose, an oxide dispersant chosen from the group consisting of: soap derivatives, anionic polyelectrolytes, anionic surfactants, and mixtures thereof, and a binder. The electrode is prepared by mixing zinc oxide with the chosen metallic oxide in an aqueous medium such as water or potassium hydroxide, stirring overnight, filtering and drying the mixture, optionally adding a further small amount of zinc oxide, optionally adding other metallic oxides, and adding hydroxy-ethyl cellulose, an oxide dispersant, and a binder. The aqueous paste os slurry thus formed is placed on a conductive substrate, drawn through a sizing gap, cut and dried, to form low cost pasted zinc oxide electrodes.
US07816033B2 Cathode active material comprising mixture of lithium/manganese spinel oxide and lithium/nickel/cobalt/manganese oxide and lithium secondary battery containing same
Provided is a high-power, non-aqueous electrolyte lithium secondary battery having a long lifespan and superior safety at both room temperature and high temperatures, even after repeated high-current charging and discharging. The battery comprises a mixture of a manganese spinel oxide and a lithium/nickel/cobalt/manganese composite oxide, as a cathode active material.
US07816027B2 System and method of controlling fluid to a fluid consuming battery
A fluid regulating system is provided for controlling fluid to a fluid consuming battery having a fluid consuming cell. The fluid regulating system includes a valve having a moving plate disposed adjacent to a fixed plate, and both having fluid entry ports to open and close a valve. The fluid regulating system also includes an actuator for moving the moving plate to open and close the valve. The actuator is controlled to open the valve when greater battery electrical output is required to operate a device and maintains the valve in the open position for a minimum required time to minimize battery capacity loss due to operation of the fluid regulating system.
US07816026B2 Battery having air electrode and biased lever gasket
A fluid consuming battery and method are provided for reducing electrode doming and providing an adequate sealed closure to the battery housing. The battery includes a cell housing having first and second housing components and at least one fluid entry port through a side of the cell housing for the passage of a fluid. The battery also has a gasket disposed between the first and second housing components. A first electrode is disposed within the cell housing in electrical contact with the first housing component and a second air electrode is provided in an electrode assembly disposed within the cell housing in electrical contact with the second housing component. The electrode assembly includes a first peripheral portion that is pre-compressed relative to a middle portion. The gasket has first and second extensions that bias against interior surfaces, and the second extension is radially inwards of an angled outward recess in the can.
US07816023B2 Magnetic recording tape having large particles in magnetic recording layer
A magnetic recording tape includes an elongated substrate and a magnetic film coated over the elongated substrate, where the magnetic film includes a first magnetic recording layer. The first magnetic recording layer includes particles having a diameter that is between a factor from about 2 to 5 greater than a thickness of the first magnetic recording layer.
US07816021B2 Carbazole-based compound and organic light-emitting device including organic layer including the carbazole-based compound
Provided are a carbazole-based compound represented by Formula 1 below and an organic light-emitting device including an organic layer including the carbazole-based compound: wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, and R14 are as defined in the specification. The carbazole-based compound has good electrical characteristics and charge transport capability, and thus, is useful as a hole injection material, a hole transport material, and/or an emitting material for fluorescent or phosphorescent devices capable of producing light of a full spectrum of colors, including red, green, blue, and white, thereby making it possible to produce an organic light-emitting device with high efficiency, a low driving voltage, and high brightness.
US07816020B2 Organic electroluminescent device
Provided is an organic electroluminescent device which is suitable for use in full-color and multicolor panels and shows higher luminous efficiency and better driving stability than organic electroluminescent devices utilizing luminescence from the singlet state. The organic electroluminescent device comprises a substrate 1 and an anode 2, organic layers, and a cathode 8 piled one upon another on the substrate, at least one of the organic layers comprises a light-emitting layer 5 containing a host material and a dopant material, and a compound having 2 to 4 pyrazole structures represented by the following formula I (wherein Ar4 to Ar6 are independently hydrogen or substituted or unsubstituted aromatic hydrocarbon groups or aromatic heterocyclic groups) is used as said host material.
US07816016B1 Electroluminescent iridium compounds and devices made therefrom
Provided are complexes of the formula: where R1 is H, R4, OR4, N(R4)2 or CHAr2; R2 is H, CnF2n+1, CnF2n+1 SO2, COOR4, or CN; R3 is H, CnF2n+1, CnF2n+1SO2, COOR4, or CN; R4 is the same or different at each occurrence and is H, alkyl, or aryl, or adjacent R4 groups can join together to form a 5- or 6-membered ring, or adjacent R4 groups can join together to form a 5- or 6-membered ring; or adjacent R4 groups can join together to form a multicyclic moiety; each Ar is independently an aryl group; L′ is a polydentate ligand that is not a phenylpyridine, phenylpyrimidine, or phenylquinoline; L″ is a monodentate ligand, and is not a phenylpyridine, and phenylpyrimidine, or phenylquinoline; m is 1, 2 or 3; n is an integer from 1 through 20; y is 0, 1 or 2; and z is 0 or an integer from 1 through 4; with the proviso that the compound is charge neutral and the iridium is hexacoordinate.
US07816015B2 Composite copper foil and method for production thereof
A composite copper foil having three layers of a supporting metal layer, an exfoliating layer and a thin copper layer, wherein one surface of the exfoliating layer comprises, as a main component, an alloy of tungsten or an alloy of molybdenum and the other surface thereof comprises, as a main component, a metal oxide containing tungsten or a metal oxide containing molybdenum. The composite copper foil is free from undesired swelling, separation or falling of the supporting metal layer during heating and working at a high temperature, and the supporting metal layer can be exfoliated from the thin copper layer with case, after the heating and the working.
US07816013B2 Wafer
A wafer has a rare earth fluoride coating disposed, typically sprayed on a substrate as an outermost layer, the rare earth fluoride being selected from lanthanoid fluorides, yttrium fluoride, and scandium fluoride. It is useful as a dummy wafer in a plasma etching or deposition system.
US07816010B2 Black matrix for color filter and its method of manufacture
A black matrix for a color filter and its method of manufacture include: forming the black matrix in a predetermined shape on a substrate to define a plurality of pixel regions: forming a light shade layer on the substrate, the light shade layer being formed of an ink-philic black material; and forming a Carbon NanoTube (CNT) layer on an upper surface of the light shade layer.
US07816009B2 Organosilyl functionalized particles and the production thereof
Particles of metal and non-metal oxides may be readily functionalized with organosilyl groups, even in the absence of catalysts, when methylene-spaced alkoxysilanes are used for functionalizing. When an excess of alkoxy groups relative to metal-OH groups are present, the resulting functionalized particles exhibit high reactivity, particularly upon exposure to moisture. Functionalization is particularly useful with particles of organopolysiloxane resins.
US07816007B2 Spherical carbon particles and their aggregates
To provide the spherical carbon particles having a novel structure different from the conventional carbon particles, uniform in shape, well dispersible in solvents and easy to handle.Spherical carbon particles of 5 nm to 100 μm in diameter having a void or voids enclosed by the carbon crystal wall, which particles have such a structure that the carbon crystal ends are exposed or the carbon net plane is looped at least at a part of the outer periphery of the particles, and an aggregate of spherical carbon particles of 5 nm to 100 μm in diameter having a void or voids enclosed by the carbon crystal wall, which aggregate has such a property that the ratio of the spherical carbon particles having a radial ratio in the range of 1.0 to 1.3 is not less than 40% by number.
US07816005B2 Copolymers for stain resistance
A method for imparting resistance to staining to a substrate comprising contacting the substrate with a copolymer comprising the monomers of Formula wherein D is at least one vinyl monomer selected from the group consisting of aryl olefin, alpha olefin and diene, each M is independently H, Ca, Mg, Al, Na, or K, each R1 is independently H, C1-C6 alkyl, or C1-C6 hydroxyalkyl, each R2 is independently linear or branched C1-C12 alkyl, C1-C6 hydroxyalkyl, C6F5, arylalkyl, C6H4OH, R3COOH, or R3SO3H, or R1 and R2 are linked together to form a morpholino or pyrrolidino ring, R3 is linear or branched C1-C12 alkyl, CH(COOH)CH2CH2, C6H4, or C6H3(OH), h1+h2 is h, h is a positive integer, k is zero or a positive integer, i and j are each independently zero or a positive integer, provided that the total of 1) h÷(k+h+i+j) is from about 0.005 to about 0.7, 2) k÷(k+h+i+j) is from about 0.3 to about 0.6, 3) [i+j]÷(k+h+i+j) is 0 to about 0.6, and provided that the sum of 1)+2)+3) is 1.0, said monomers occurring in any sequence.
US07816004B1 Three-dimensional carbon fibers and method and apparatus for their production
This invention relates to novel three-dimensional (3D) carbon fibers which are original (or primary) carbon fibers (OCF) with secondary carbon filaments (SCF) grown thereon, and, if desired, tertiary carbon filaments (TCF) are grown from the surface of SCF forming a filamentous carbon network with high surface area. The methods and apparatus are provided for growing SCF on the OCF by thermal decomposition of carbonaceous gases (CG) over the hot surface of the OCF without use of metal-based catalysts. The thickness and length of SCF can be controlled by varying operational conditions of the process, e.g., the nature of CG, temperature, residence time, etc. The optional activation step enables one to produce 3D activated carbon fibers with high surface area. The method and apparatus are provided for growing TCF on the SCF by thermal decomposition of carbonaceous gases over the hot surface of the SCF using metal catalyst particles.
US07816002B2 Recording paper
A recording paper contains a pulp fiber and a magnetic fiber having a large Barkhausen effect. The fiber orientation ratio of this recording paper by an ultrasonic propagation velocity method is in a range of more than 1.3 to less than 1.8, and the degree of shrinkage in an MD thereof is 0.25% or less.
US07815999B2 Insulated conductive particles and anisotropic conductive adhesive film containing the particles
An insulated conductive particle for an anisotropic conductive film is disclosed. One embodiment of the particle includes a conductive particle and insulating fixative particles discontinuously fixed on the surface of the conductive particle. The insulating particles provides insulation with other adjacent insulated conductive particles, while the insulated conductive particle is electrically connected between electrodes with the insulating fixative particles being deviated from its position. The instant disclosure also provides a method for manufacturing the insulated conductive particle, an anisotropic conductive adhesive film containing the insulated conductive particles, and an electrically connected structure using the film.
US07815998B2 Conductive polymer foams, method of manufacture, and uses thereof
Articles are disclosed, comprising a polymer foam layer having a first surface and an opposite second surface; a plurality of cells between the first surface and the opposite second surface of the polymer foam layer, wherein the thickness of the polymer foam layer between the first surface and the opposite second surface is 1.0 to 1.5 times the average height of the plurality of cells; and a plurality of magnetic, electrically conductive particles aligned into a plurality of mutually isolated chains that essentially continuously span the foam between the first surface and the opposite second surface of the polymer foam layer. The foams are useful as gaskets for electromagnetic shielding, grounding pads, battery contact conductive spring elements, and the like.
US07815996B2 Low gloss and low haze laminated polyester film including talc and method for preparing same
A polyester film that possesses both reduced gloss and reduced haze is achieved. The film includes at least one sub layer including talc and at least one core layer. The surface layer has a lower melting point temperature than the core layer.
US07815989B2 Selectively tearable stock material for a dunnage conversion machine
A stock material (16) for use with a dunnage conversion machine (14) includes at least one ply of sheet material having spaced along the length thereof a plurality of transverse rows (22) of weakened areas (24). The weakened areas (24), which can be formed by perforations, for example, have a reduced strength relative to adjacent portions of the sheet material. Each row (22) of weakened areas (24) has at least one parameter that varies along the row (22). The strength of the stock material at the row (22), in response to a force applied across the row (22), varies across the stock material (16).
US07815984B2 Recording medium and image forming method using the same
The invention provides a recording medium comprising a porous cellulose layer containing at least one cellulose selected from the group consisting of lightly-beaten cellulose pulp, mercerized cellulose and fluffed cellulose and a porous filler internally loaded therein, and a recording medium further comprising an ink-receiving layer.
US07815975B2 Catheter having polymer stiffener rings and method of making the same
A catheter and method of making a catheter are disclosed in which the catheter is highly flexible and yet resistant to crushing and kinking. The catheter is made by applying rings of hard polymer material along the tubular shaft as the catheter is manufactured. The catheter thus has a plurality of hard polymer rings formed at spaced locations along its length, and soft segments between the hard polymer rings that allow the catheter to remain very flexible. The hard polymer rings improve the radial strength of the catheter and make the catheter resistant to crushing and kinking.
US07815974B2 Gas diffuser membrane with coated substrate
A flexible diffuser membrane for diffusing gas into a liquid includes a substrate covered wholly or partially by a thin fluorocarbon elastomer coating. The coating is applied after the substrate has been fully constructed and cured. The coating is then mixed with an adhesive catalyst and applied by spraying or in another suitable manner to the substrate. The substrate and coating are then heated to a temperature such as 350° F.-800° F. adequate to form a strong chemical, molecular and adhesive bond between the coating and substrate. Perforations are formed in the membrane, the substrate may be treated with a biocide allowing the uncoated edges of the perforations to be coated with the biocide and resist biological growth.
US07815971B2 Method for making nanostructures with chromonics
Methods of forming nanostructures with chromonic materials are disclosed. A method includes coating a substrate surface with a chromonic solution to form a chromonic layer, removing at least a portion of the water to form a dried chromonic layer, and exposing the dried chromonic layer to an organic solvent to form a pattern of channels within the dried chromonic layer. The chromonic solution includes a chromonic material and water. Materials can be deposited within the channels to form a pattern of nanostructures.
US07815970B2 Controlled polarity group III-nitride films and methods of preparing such films
The present invention provides methods of preparing Group III-nitride films of controlled polarity and substrates coated with such controlled polarity films. In particular, the invention provides substrate preparation steps that optimize the substrate surface for facilitating growth of a Group III-polar film, an N-polar film, or a selectively patterned film with both a Group III-polar portion and an N-polar portion in precise positioning. The methods of the invention are particularly suited for use in CVD methods.
US07815968B2 Centrifugal method for filing high aspect ratio blind mirco vias powdered materials for circuit formation
The present disclosure relates generally to semiconductor, integrated circuits, and particularly, but not by way of limitation, to centrifugal methods of filling high-aspect ratio vias and trenches with powders, pastes, suspensions of materials to act as any of a conducting, structural support, or protective member of an electronic component.
US07815962B2 Coated stent with evenly distributed therapeutic agent
A stent includes a stent framework and a coating disposed on the stent framework. The coating includes an inner surface and an outer surface. The coating has a circumferential therapeutic concentration zone near the inner surface and a circumferential washed zone near the outer surface.
US07815957B2 Cheese compositions and related methods
Cheese compositions and methods of making cheese compositions, including methods of formulating cheese compositions are provided. Cheese compositions of the invention include casein protein, non-casein protein, non-pregelatinized, modified starch, and a fat component having a low amount of trans-fat (e.g., about 5% or less of trans-fat by weight of the fat component) while at the same time substantially maintaining and/or improving properties (e.g., processing properties, organoleptic properties, combinations of these, and the like) of the cheese composition.
US07815954B2 Frozen confection dispenser and associated methods
A dispenser for a soft-serve food product includes a housing having a dispensing chute and a piston having a head positioned therewithin. A lateral wall, the piston head, and a front door define an enclosed hollow space. The head is slidable within the lateral wall for squeezing a deformable container to dispense product through the chute. A system for preparing and dispensing a soft-serve food product includes a tempering freezer for raising a temperature of the food product from hard-frozen to a condition for soft-serve dispensing. An apparatus for packaging a soft-serve confection into a multiple-serving-size container for transport includes a blender for blending ingredients together to form a blended product and a device for transferring the blended product into a deformable container. The deformable container filled with the blended product is transferred into a substantially rigid mold and frozen to a hardened state for transport and retention.
US07815953B2 Capsules containing a substance in powder form from which a beverage, preferably espresso coffee, is to be extracted
A capsule for extracting a beverage from a substance in powder form, preferably ground coffee, by means of pressurized water, comprising a box-like body which contains the substance in powder form and has a base provided with an output port for the outflow of the extracted beverage, the output port being closed by an elastic crema forming septum which can open under the pressure of the water, the capsule further comprising a safety lid which is mounted on the box-like body at the base so as to increase the axial size of the box-like body, the lid comprising a shoulder which is engaged on the septum and is adapted to retain the septum within the capsule.
US07815947B2 Nutritional composition for controlling blood sugar level
A nutritional composition for controlling blood sugar level comprising a protein, a lipid and a carbohydrate, wherein energy percentages supplied by the protein, lipid and carbohydrate are 10 to 25%, 20 to 35% and 40 to 60%, respectively; and oleic acid in the lipid energy percentage is 60 to 90% and palatinose and/or trehalulose in the carbohydrate energy percentage is 60 to 100%, which is useful as an oral or tube feeding nutrient for nutritional management or blood sugar level control of patients suffering from diabetes and glucose intolerance, or for obesity prevention, a therapeutic diet, a diet for diabetic patients at home, an obesity preventive diet or a food with health claims.
US07815946B1 Anti-diabetic and cholesterol lowering preparation from fenugreek seeds
The invention relates to a composition having blood glucose-lowering and cholesterol-lowering activity that can be obtained from seeds of the Papilinaceae Leguminosae family, for example, fenugreek seed. Methods of obtaining the composition from seed and seed parts are provided. Therapeutic methods of using the composition, such as for treating diabetes and hypercholesterolemia, are also a part of the invention.
US07815943B2 Cardiovascular therapy composition including transfer factor and therapeutic methods including use of the composition
A composition for use in cardiovascular therapy includes transfer factor. The transfer factor may be nonmammalian transfer factor, such as that derived from eggs, or mammalian transfer factor, such as that derived from colostrum. The composition may also include one or more of the following: an LDL receptor-binding element; a blood flow-enhancing element; a cholesterol reducing element; a fat oxidation prevention element, and an antioxidant. Treatment methods include enlisting the immune system of a subject receiving therapy to attack pathogens that cause inflammation of blood vessels or to otherwise reduce inflammation of blood vessels.
US07815940B2 Gastric acid secretion inhibiting composition
An oral pharmaceutical dosage form comprises pharmacologically effective amounts of an acid susceptible proton pump inhibitor or a salt thereof, an H2 receptor antagonist or a salt thereof and a pharmaceutically acceptable carrier. The dosage form is capable of raising gastric pH to above 4 within two hours after administration and to keep it at that level for at least 4 hours. Also disclosed is a method of manufacture of the dosage form, its use in treating dyspepsia and infection by Helicobacter pylori, and a method of treating disorders associated with gastric acid secretion.
US07815938B2 Film coating
A film coating composition suitable for use in coating pharmaceutical formulations to provide modified release comprising a dispersion which includes: a) an acrylic polymer, b) a vinyl acetate polymer, and c) a water-containing liquid. The film coat is useful for the achievement of modified release from pharmaceutical formulations such as tablets, pellets, etc.
US07815937B2 Quick dissolve compositions and tablets based thereon
The invention provides a composition useful for making oral dosage forms capable of dissolving in the mouth in less than 40 seconds without the need for a conventional super disintegrant and having a friability of less than 1%; wherein the composition includes liquiflash particles and an excipient mass. A preferred excipient mass according to the invention contains a directly compressible inorganic salt; a cellulose derivative or a combination of a directly compressible inorganic salt and a cellulose derivative. Preferably, the liquiflash particles and the excipient mass are combined in proportions such that the active ingredient remains substantially within the microspheres when the composition is compressed to obtain a dosage form having a hardness of 20 to 50 N. The compositions of the invention allow for the fabrication of oral dosages having improved hardness and friability.
US07815934B2 Sequestering subunit and related compositions and methods
A sequestering subunit comprising an aversive agent and a blocking agent, wherein the blocking agent substantially prevents release of the aversive agent from the sequestering subunit in the gastrointestinal tract for a time period that is greater than 24 hours; a composition comprising a sequestering subunit and a therapeutic agent in releasable form, wherein, optionally, the mechanical fragility of the sequestering subunit is the same as the mechanical fragility of the therapeutic agent in releasable form; a capsule or tablet comprising a sequestering subunit and a therapeutic agent; and a method of preventing abuse of a therapeutic agent.
US07815932B2 Patch containing fentanyl for mucous membrane of oral cavity
To provide a patch containing fentanyl for mucous membrane of the oral cavity (oral transmucosal fentanyl), which rapidly increases the serum concentration of the drug, is easy in handling and is superior in safety. The patch can be prepared by laminating on one side of a drug layer which contains fentanyl or its salt as an active ingredient, methyl vinyl ether-maleic anhydride copolymer as an adhesive, and at least one substance selected from the group consisting of hydroxypropylcellulose, hydroxypropylmethylcellulose and hydroxyethylcellulose as a thickener, a support layer hardly soluble or insoluble in water, and a backing in this order.
US07815930B2 Food and feed supplement and its use
The present invention relates to a food and feed supplement, and its use, where the supplement comprise as the basic component at least one carboxylic acid and/or its salt, an iron component and vitamins B6, B9 and B12 in amounts corresponding to at least that which theoretically can be consumed during the metabolism of the COOH-groups present. The supplement may also contain a desiccant and an antioxidant. The supplement will have a pH in the range 2.0-6.0 when dissolved in water. The supplement is characterized in that the amounts of the vitamins B6, B9 and B12 are in the range of 0.5-30 mg, 0.1-10 mg and 1-1500 μg/gram dry weight of the content of the pure carboxylic acids in the supplement, respectively. The supplement can be used in animal feed in amounts of 0.5-15 grams dry supplement/kg dry feed.
US07815927B2 Terpolymers for controlled release of bioactive agents from implantable medical devices
Disclosed herein are implantable medical devices comprising controlled release terpolymers and at least one drug releasable from said terpolymers coating. The terpolymers of the present invention are comprised of acrylate and/or vinyl monomers.
US07815924B2 Cosmetic composition containing microcrystalline cellulose
A sprayable cosmetic composition is disclosed. In one aspect, the composition comprises a sunscreen agent or mixture of sunscreen agents; an emulsifier or mixture of emulsifiers; optionally an emollient or mixture of emollients; a rheology control agent; and water. The rheology control agent is microcrystalline cellulose. When sprayed on the skin or hair, the cosmetic compositions of the invention produce a fine mist that deposits evenly with no dripping and no aggregate or blobs.
US07815923B2 Implantable graft material
Described are graft materials suitable for implantation within a patient including isolated tissue material remodeled in a body cavity. Also described are methods of treating a patient that include implanting these materials and prosthetic devices comprising these materials within the patient's body.
US07815914B2 Methods for the treatment of cellular proliferative disorders
The present invention relates to methods of identifying the susceptibility of cells to reovirus infection by measuring constitutive ras-MAP signaling. The invention also pertains to methods using reovirus for the treatment of cellular proliferative disorders, and particularly cellular proliferative disorders wherein the proliferating cells exhibit constitutive MAPK phosphorylation, in mammals. In particular, the methods provide for reovirus treatment of mammals to treat proliferative disorders which include breast tumors, a subset of tumors in which mutation of the ras gene is not believed to play a significant role.
US07815911B1 Compositions and methods for treating Yersinia pestis infection
Compositions and methods for treating a Yersinia pestis (Y. pestis) infection are provided. Compositions and methods of for inducing an immune response in a subject are provided. Composition can include a YadC polypeptide.
US07815910B2 Vaccine composition and use of surfactants as adjuvants of immunity
A composition comprising an aqueous solution comprising: (i) at least one antigen or at least one in vivo generator of a compound comprising an amino acid sequence, and (ii) as an adjuvant of immunity, a surfactant, or a mixture of surfactants, having an overall HLB number of between 5 and 15.
US07815906B2 Compositions and methods for restoring sensitivity to treatment with HER2 antagonists
Methods and compositions for restoring growth inhibition sensitivity to a tumor cell resistant to growth inhibition by HER2 antagonists. The methods involve administering a PCDGF antagonist to the cell in an amount effective to stimulate or restore growth inhibition sensitivity to HER2 antagonists. The invention also provides treatment regimens, and therapeutic compositions comprising an HER2 antagonist and a PCDGF antagonist.
US07815896B2 Type III secretion pathway in Aeromonas salmonicida and uses therefor
Disclosed is a newly identified and characterized type III secretion system in Aeromonas salmonicida. The invention also encompasses the use of components of the novel secretion system in immunoprotection against A. salmonicida infection, as well as other diagnostic and therapeutic uses thereof.
US07815894B2 Compounds, compositions and methods for medical imaging of neuropsychiatric disorders
Compounds, compositions and methods for the diagnosis of Alzheimer's disease. Synthesized Glycerophosphocholine (GPC) may be used as a diagnostic aid to measure progression of Alzheimer's disease. GPC is a membrane phospholipid metabolite that is capable of binding specifically to the β-turn of beta amyloid (Aβ) peptide. Compounds including non-radioactive, paramagnetic, and radioactive derivatives of GPC are presented. These compounds possess similar binding properties to original GPC molecules and are useful in medical magnetic resonance imaging and/or positron emission tomography applications. By employing these radiological techniques in conjunction with the compositions of the present invention, the diagnosis and assessment of the progression of Alzheimer's disease may be achieved.
US07815890B2 Process for tritium removal from water by transfer of tritium from water to an elemental hydrogen stream, followed by membrane diffusion tritium stripping and enrichment, and final tritium enrichment by thermal diffusion
A diffusion based process for tritium removal from water by tritium transfer from water to an elemental hydrogen stream, followed by a membrane diffusion cascade for tritium stripping and enrichment, and final tritium enrichment by one or more thermal diffusion columns. The combination of process steps takes advantage of membrane diffusion's large throughput capability at low tritium concentration with the simplicity of thermal diffusion for small throughput final tritium enrichment. The membrane diffusion stages use supported or unsupported microporous or hydrogen permeable metal membranes (such as Pd/Ag alloy). The diffusion process is compatible with any front-end process to transfer tritium from tritiated water to elemental hydrogen. The process may be designed and operated at low pressure, with small gas inventory, and no inherent overpressure hazard.
US07815888B2 Method of producing secondary battery cathode material, and secondary battery
Disclosed is a process for producing a secondary battery cathode material by calcining raw materials. The process is characterized by calcining the raw materials together with one or more substances, which are selected from the group consisting of hydrogen, water and water vapor, and conductive carbon and/or a substance, which can form conductive carbon by pyrolysis, added thereto. As crystals of the secondary battery cathode material obtained by this process have been controlled fine sizes, the secondary battery cathode material promotes movements of ions of an alkali metal led by lithium between the interiors of grains of the cathode material and an electrolyte to suppress polarization in an electrode reaction, and further, increases an area of contact between the positive material and a conductivity-imparting material to provide improved conductivity so that improvements are assured in voltage efficiency and specific battery capacity.
US07815882B2 Method and apparatus for refining boron-containing silicon using an electron beam
In a refining method for boron-containing silicon, boron-containing silicon is irradiated with an electron beam in a vacuum vessel to melt the boron-containing silicon. A boron compound-forming substance is introduced into the vacuum vessel, and boron contained in the molten silicon is formed into a boron compound. After at least a portion of the boron compound has vaporized, irradiation with the electron beam is stopped. The high-purity molten silicon can then be solidified.
US07815877B2 Sterilizing device for sterilizing closures
The invention relates to a sterilizing device (10) for sterilizing closures (16), such as lids and caps for containers, such as bottles and jars, which device comprises a housing (12), provided with a closure entry (14) for supplying closures, a closure exit (18) for discharging sterilized closures from the device, a sterilizing-agent feed (21) for feeding sterilizing agent into the device and a discharge (28; 30) for discharging used sterilizing agent, as well as pass-through means (20) for passing closures (16) through the housing (12), the pass-through means (20) comprising a non-rectilinear pass-through path (58) in the plane parallel to the main plane of the closures. A sterilizing method is also described.
US07815876B2 Reactor pump for catalyzed hydrolytic splitting of cellulose
The reactor pump for hydrolytic splitting of cellulose is configured to pump cellulose, under high pressure, with low availability of sugar into a reactor. The reactor has an upstream transition segment connected to a downstream reaction chamber. The transition segment has an inlet that is smaller than the outlet. The inner walls taper outward. The chamber has an inlet that is larger than the discharge outlet. The inner walls taper inward. The transition segment outlet has an area that is substantially the same as the area of the chamber inlet. Back pressure in the chamber forms a cellulose plug within the inlet of the transition segment. The plug stops cellulose from escaping out the inlet. High pressure pumping forms a cellulose plug within the discharge outlet of the chamber. The plug slows downstream movement of the cooking cellulose giving the cellulose time to cook. Cooking cellulose begins to breakdown under heat and the injection of acid, if required. The outer surface of the plug is cooked faster than the inner core and in the process the faster cooking portion of the plug becomes a liquefied slurry. The slurry lies between the inwardly tapering chamber walls and the less cooked inner core. The slurry slides faster towards the discharge outlet than does the inner core. As the slurry moves downstream in the chamber, the surface of the inner core moves to the walls and in turn is liquefied. Cellulose may be pre-treated prior to entry in the reactor by the addition of water and a weak acid such as sulfuric or ammonium. The cellulose may be granulated to provide more surface area to assist break down in the reactor.
US07815871B2 Droplet microactuator system
The present invention relates to a droplet microactuator system. According to one embodiment, the droplet microactuator system includes: (a) a droplet microactuator configured to conduct droplet operations; (b) a magnetic field source arranged to immobilize magnetically responsive beads in a droplet during droplet operations; (c) a sensor configured in a sensing relationship with the droplet microactuator, such that the sensor is capable of sensing a signal from and/or a property of one or more droplets on the droplet microactuator; and (d) one or more processors electronically coupled to the droplet microactuator and programmed to control electrowetting-mediated droplet operations on the droplet actuator and process electronic signals from the sensor.
US07815869B2 Catalytic converter with mid-bed sensor
A catalytic converter assembly is provided that includes a metallic tubular member having a first end and a second end. A first substrate is disposed within the metallic tubular. A second substrate is disposed within the metallic tubular member. A spacer is axially positioned the between the first and second substrate that includes a cylindrical body with a first wall and a second wall formed substantially perpendicular to the cylindrical body. The first wall abuts an end of the first substrate for retaining the first substrate between the first end and the first wall for preventing movement. The second wall abuts an end of the second substrate for retaining the second substrate between the second end and the second wall for preventing movement.
US07815868B1 Microfluidic reaction apparatus for high throughput screening
An SBS-formatted microfluidic device where the geometry of the plate defines an array of interrogation areas, and where each interrogation area encompasses at least one reaction site.
US07815867B2 Smart addition system
An addition apparatus, a fluid catalytic cracking (FCC) system having an addition apparatus, and a method for adding material to an FCC unit are provided. In one embodiment, an addition system having the capability of interfacing with a material container is provided that allows the addition system to obtain information relating material held in the container. In one embodiment, at least some of the information is contained on a tag affixed to the container. Other information may be retrieved and/or sent to the addition system controller from a remote data source, such as a catalyst supplier.
US07815866B2 Apparatus and method for handling fluids for analysis
A reaction vessel with a bottom drain opening supporting a selected unpressured head of fluid by the surface tension of the fluid. A device processing zone includes a support for spaced rows of reaction vessels, passages communicating with their drain openings of supported vessels, and a pressure source for selectively draining fluid through the drain openings. Generally horizontal bar magnets are supported for selected vertical movement between the vessel rows. A dispensing head has X discharge openings selectively positionable over X selected reaction vessels. A metering pump mechanism selectively meters X a selected quantity of fluid a bulk supply (where X is at least four), and selectively pumps the metered selected quantities through the drain openings to the selected reaction vessels. Methods of drawing fluid from the vessels using the pressure source, and moving the magnets to form a pellet of analyte are also included.
US07815864B2 Polysilazane thermosetting polymers for use in chromatographic systems and applications
This invention relates to an amorphous non-glassy ceramic composition that may be prepared by curing, calcining and/or pyrolyzing a precursor material comprising silicon, a Group III metal, a Group IVA metal, and/or a Group IVB metal.
US07815857B2 Device for taking-up and studying or manipulating a sample liquid in a microfluidic platform
A device and a plurality of microfluidic platforms for taking up and especially studying or manipulating a sample liquid, a measuring instrument for use with the device and platforms, and a process for performing the studying or manipulating of the sample liquid. Very simple, hygienic and user-friendly handling is enabled in that the platforms which are connected to one another in a sealed state and can each be individually separated and individually, preferably simultaneously, opened for taking up of a sample, such as blood, for, e.g., performing a glucose determination.
US07815856B2 Storage container for detecting presence of checmical elements
A container having an indicator for detecting the presence of chemical elements is provided. In one embodiment, the container comprises a cavity therein for receiving an article having a first metallic element, the cavity being substantially sealed from a surrounding environment outside the container. An indicator is disposed within the sealed cavity, the indicator having a second metallic element with a standard potential less than the standard potential of the first metallic element, whereby a change in state of the second metallic element alerts an operator to the presence of a predetermined chemical element within the container.
US07815854B2 Electroluminescent illumination source for optical detection systems
An optical detection system that utilizes an electroluminescent (EL) illumination source is provided. Unlike illumination sources used with some conventional optical detection systems, an EL device is relatively homogeneous and diffuse, and thus may provide uniform illumination to the test sample. In addition, the emitted light intensity of the EL device may be easily controlled by simply varying the voltage or the frequency of the applied current. The relatively flexibility of EL devices may also allow them to be readily incorporated into a chromatographic-based assay device for detecting the presence or absence of an analyte within a test sample.
US07815852B2 Method, apparatus and software program for measurement of a parameter relating to a heart-lung system of a mammal
A method, apparatus and software program for measuring a parameter relating to the heart-lung system of a mammal are described. The method, software and apparatus can be implemented in a dialysis or other blood treatment apparatus comprising an extracorporeal blood circuit connected to a mammal; the circuit comprises a dialyzer, or other treatment unit, having a blood inlet, a blood outlet, a treatment fluid inlet and a treatment fluid outlet. The method comprises the steps of providing a pulse of a detectable substance in the blood circuit, measuring an integrated concentration of the detectable substance on the dialysis fluid outlet, determining the parameter based on the measurements on the dialysis fluid outlet.
US07815843B2 Process for anode treatment of solid oxide fuel cell—membrane electrode assembly to upgrade power density in performance test
This invention describes the process for fabrication of a high conductivity and low resistance solid oxide fuel cell. An anode substrate is mainly prepared via tape casting technique and modified by abrasion and polish process. Electrolyte is fabricated onto the polished side by thin film technologies and can attach well in the cross section. Grinding surface of anode side about 10-30 μum after finish of MEA combination can get a high conductivity and low resistance unit cell and enhance cell performance effectively.
US07815841B2 Fiber cement composite materials using sized cellulose fibers
This invention discloses a new technology related to cellulose fiber reinforced cement composite materials using cellulose fibers that are treated with inorganic and/or organic resins to make the fibers more hydrophobic, as well as other chemical treatments. This invention discloses four aspects of the technology: fiber treatment, formulations, methods and the final product. This technology advantageously provides fiber cement building materials with the desirable characteristics of reduced water absorption, reduced rate of water absorption, lower water migration, and lower water permeability. This invention also impart the final products improved freeze-thaw resistance, reduced efflorescence, and improved rot and UV resistances, compared to conventional fiber cement products. These improved attributes are gained without loss in dimensional stability, strength, strain or toughness. In some cases the physical and mechanical properties are improved. This invention also discloses the method of treating cellulose fibers with various chemicals to impart the fiber hydrophobicity for applications in the fiber reinforced cement composite materials.
US07815840B2 Modular mold system and related method
A modular mold system includes a hot half and a cold half. The hot half has a heated distributor assembly to receive molding material from an injection molding machine. The distributor assembly has a forward side that is opposite a side of the distributor assembly that faces the injection molding machine. A plurality of heated multi-nozzle units may also be provided. Each multi-nozzle unit has a manifold and a plurality of forward-extending nozzles. Each multi-nozzle unit is individually forwardly removably fastened to the forward side of the distributor assembly and removable from the distributor assembly while the distributor assembly is fastened to the first platen. The cold half includes a mounting plate and a plurality of cold-side units associated with the multi-nozzle units. Each cold-side unit is removably fastened to the mounting plate and engagable with one of the multi-nozzle units to define the one or more mold cavities.
US07815833B2 Method for producing injection-molded parts
In a method for producing injection-molded parts, PET material is processed and/or plasticized by means of a twin-screw extruder having a plurality of processing zones. At least two processing zones are implemented as degassing zones. The processed and/or plasticized material is transferred to a transfer reservoir and then further processed by a piston unit.
US07815832B2 Manufacture of cellulose ester filaments: lubrication in the spinning cabinet
In the manufacture of cellulose ester fibers, a dope is extruded into filaments. Extrusion occurs in an elongated cabinet having an outlet for the filaments. The filaments are taken up after exiting the outlet. The filaments are lubricated at the outlet of the cabinet.
US07815827B2 Method of producing slabs of artificial stone and polymerisable resin having a veined effect by means of vibro-compression under vacuum
The invention relates to a process for manufacturing artificial stone boards with polymerizable resins with a “veined effect” by means of the vibro-compaction under vacuum system comprising a first grinding phase of the different materials forming the filler, a second phase containing a resin with the catalyst and optionally a third phase consisting of the mixing of the two previous phases until the homogenization of the materials with the resin, a fourth phase of moulding and compaction of the obtained paste by vibro-compression under vacuum, a fifth hardening phase by polymerization of the resin by means of heating and a last cooling, cutting and polishing phase.
US07815814B2 Method and system for dry etching a metal nitride
A method and system of etching a metal nitride, such as titanium nitride, is described. The etching process comprises introducing a process composition having a halogen containing gas, such as Cl2, HBr, or BCl3, and a fluorocarbon gas having the chemical formula CxHyFz, where x and z are equal to unity or greater and y is equal to 0 or greater.
US07815809B2 Method for conductivity calculation in a treatment fluid upstream and downstream a filtration unit in apparatuses for the blood treatment
A method for conductivity calculation in a treatment fluid downstream a filtration unit in a blood treatment apparatus is provided. The conductivity calculation is then used for clearance and fistula flow determination. A flow of treatment fluid is created in the filtration unit; a change in the conductivity of the treatment fluid at the inlet of the filtration unit is imposed to cause an induced conductivity change in the fluid at the outlet of the filtration unit; a predetermined number of conductivity values Cdo downstream from the filtration unit are measured. The measured conductivity values define a curve the pattern of which is estimated by means of one interpolating mathematical function in an interval of time after the occurrence of the induced conductivity change; a characteristic measuring time tcalcclr is determined. The value of the interpolating mathematical function at the characteristic measuring time tcalcclr represents the conductivity value Cdo2 of the treatment fluid downstream from the filtration unit after the induced conductivity change.
US07815802B2 Grafted photo-polymerized monolithic column
The present invention relates to the fabrication of a grafted, UV photo-polymerized silica-based monolithic column and the use of such column for the extraction of DNA. In one embodiment, a method is provided for fabricating a silica-based monolithic column, wherein a vessel is filled with a polymerization mixture that is formed into monolithic solid phase for DNA extraction through in situ photo-polymerization.
US07815798B2 Discrete drop dispensing device and method of use
A discrete drop dispensing device comprises a substrate comprising an upper surface and a lower surface and orifices extending from the upper surface to the lower surface, adapted to receive a fluid at a flow rate. The discrete drop dispensing device also comprises an oscillator disposed adjacent to the substrate and configured to vibrate the substrate to expel drops having a substantially equal volume of the fluid. The flow rate is substantially identical to a drop dispensing rate. A method and a device for performing liquid chromatography are also described. The method comprises automatically adjusting the drop dispensing rate to a change in the flow rate or a change in a composition of a mobile phase of the fluid.
US07815797B1 Pool, skimmer pre-filter assembly
A pre-filter assembly is for use in a skimmer of a residential swimming pool. The pre-filter comprises a skimmer collar and a cleanable filter basket. The skimmer collar is for placement on a rim of a below water surface opening within the skimmer. The cleanable filter basket is made of a water porous material. The filter basket is permanently secured at an edge defining the open-top to the skimmer collar. The filter basket further has a chevron shape for ease of use. Swimming water debris is trapped in the filter basket as pool water is pulled through the filter basket on its way to a primary filter apparatus. The filter basket is easily cleaned as needed and replaced.
US07815795B2 Pool skimmer adapter
This invention describes a ring shaped adapter that is adapted to fit within a pool skimmer and have a pressure cap that will prevent debris from inadvertently being deposited within the pump system of the pool under construction. The ring shaped adapter and pressure cap will allow the pool to be drained using the pump system, without any additional equipment.
US07815790B2 Upgrade of visbroken residua products by ultrafiltration
This invention relates to a process of producing an upgraded product stream from the products of a resid visbreaking process to produce an improved feedstream for refinery and petrochemical hydrocarbon conversion units. This process utilizes an ultrafiltration process for upgrading select visbreaking process product streams to produce a conversion unit feedstream with improved properties for maximizing the conversion unit's throughput, total conversion, run-time, and overall product value.
US07815787B2 Electrolyte retaining on a rotating platen by directional air flow
A method and apparatus for retaining electrolyte on a rotating platen using directional air flow is provided. In one embodiment, an apparatus for processing a substrate is provided. The apparatus includes a platen assembly having a surface for supporting a processing pad and disposed on a stationary base so that the platen assembly may rotate relative to the base; and an air knife coupled to the base and extended over a portion of the surface, the air knife operable to deliver a stream of air toward the pad to divert at least a portion of a fluid disposed on the pad toward a center of the pad.
US07815784B2 Electro-composite coating for flexible seals and method of applying the same
An electro-composite tribological coating for coating a flexible or compliant structure, for example a structural seal, includes a cobalt and cobalt alloy base containing a fine dispersion of tribologically suitable particles such as chromium carbide (Cr3C2), silicon carbide (SiC), carbon graphite, and the like, which can be deposited directly on the outer surface of the seal as a near-net shape coating requiring little or no mechanical polishing or grinding. The coating is deposited on the seal in one embodiment by an electrolytic bath. In this manner, a near-net shape coating of a desirable thickness, for example having a thickness of about 0.005″ and a desirable surface finish can be achieved in the as-plated condition with little or no additional polishing or grinding after coating.
US07815769B2 Sanitary paper
It is intended to provide sanitary paper which is excellent in texture such as moistness and softness and scarcely causes skin irritation or blushing even if it is brought into contact with the skin frequently. Namely, sanitary paper having an oil absorbance specified in JIS P8141 of 7 mm or less and a moisture content of from 9.50 to 15.00% (measured in accordance with JIS P8127 after conditioning in accordance with JIS P8111); carrying a solution, which contains a moistening agent, a softener, an antioxidant and so on, coated in a dose of 46.0 to 160.0 mg/cm3 of the paper base; and having a bending hardness B measured with the use of a pure bending machine of from 0.0040 to 0.0060 g·cm2/cm.
US07815767B2 Plasma processing apparatus
A plasma processing apparatus of the present invention can reduce a manufacturing cost of the apparatus and a footprint by decreasing a load applied to a device for varying a distance between electrodes in comparison with a conventional apparatus and, at the same time, easily meet a scaling up of a substrate to be processed. A lower electrode and an upper electrode are installed inside a vacuum chamber. Provided at a lower electrode supporting member are openings for operating the upper electrode by using a driving mechanism installed outside the vacuum chamber. An intermediate ring is installed at bellows for air-tightly sealing the openings. Further, the intermediate ring is connected to a connecting member connected to an upper electrode supporting member and the driving mechanism.
US07815765B2 Method for forming laminated synthetic leather
A method for forming a laminated synthetic leather includes engaging a textile carrier onto a carrying roll, extruding one or more materials with an extruder machine into a film, and feeding the film downwardly onto a lamination roll to have the film carried on a portion of an outer peripheral portion of the lamination roll and to have the film to be suitably cooled by the lamination roll. The film and the textile carrier are then compressed together with the rolls, to form the laminated synthetic leather, and to prevent the film from penetrating into the textile carrier to a greater extent, and to form a soft or flexible laminated synthetic leather.
US07815764B2 Apparatus and method for carrying out a continued union of paper webs
Apparatus for continually joining paper webs, comprising a device able to compress the webs (5,6) onto an impression cylinder or roller (4) while the webs advance toward an outlet section of the apparatus. The compressive device includes a roller or cylinder (2) which exhibits a hard outer surface (20) supported by an underlying elastic surface (23).
US07815761B2 Apparatus and method for applying labels
A method and apparatus enables linered label applicators to use labels on thin liners. Linered labels comprise a composite of an elongate sheet of thin or light-weight temporary liner having a precut label adhered to a low adhesion surface. The cut-out labels on the liner are fed into the linered label applicator. The use of support mechanisms other then vacuum application on rollers enables the use of thinner liner sheets on labels. A die head for cutting or perforating labels comprising adhesive on label stock comprising a die head having at least 80% of its outer surface comprising flat areas between cutting edges, multiple cutting edges on the outer surface, and an internal volume in the die head, the internal volume for carrying coolant liquid into and out of the volume so as to cool the outer surface of the die head when the coolant temperature is at least 10° C. cooler than the outer surface of the die head.
US07815759B1 Electrostatic charge dissipation system statement regarding federally sponsored research or development
An electrostatic charge reduction system including a composition having at least one energetic particle component with or without a non-conducting binder, and conducting polymer or electrically neutral polymer deposited on the energetic component in its oxidized form. The oxidation of the polymer occurs during or after the polymer deposition process.
US07815758B2 High damage tolerant Al-Cu alloy
Disclosed is a high damage tolerant Al—Cu alloy of the AA2000 series having a high toughness and an improved fatigue crack growth resistance, including the following composition (in weight percent) Cu 3.8-4.7, Mg 1.0-1.6, Zr 0.06-0.18, Cr<0.15, Mn>0-0.50, Fe≦0.15, Si≦0.15, and Mn-containing dispersoids, the balance essentially aluminum and incidental elements and impurities, wherein the Mn-containing dispersoids are at least partially replaced by Zr-containing dispersoids. There is also disclosed a method for producing a rolled high damage tolerant Al—Cu alloy product having a high toughness and an improved fatigue crack growth resistance, and applications of that product as a structural member of an aircraft.
US07815757B2 Water-cooling method of steel material
The oxide film thickness of the steel material surface (dH2O+do2) is made to become 15 nm or less where post-treatment after water-cooling is not needed by suitably setting the conditions of the water-cooling start temperature (Ti), water-cooling end temperature (To), steel material thickness (d), concentration of solute oxygen in the cooling water (Do), and cooling rate (CR) in the equation of dH2O+do2=7.98×10−4(Ti−To)dDo+{5.50×10−3(Ti2−To2)−6.51(Ti−To)}/CR.
US07815753B2 Fe-based bulk amorphous alloy compositions containing more than 5 elements and composites containing the amorphous phase
Disclosed is a Fe-based bulk amorphous alloy composition which forms a bulk amorphous substance due to its excellent amorphous formability when it is cooled to a temperature lower than its glass transition temperature from the liquid state at a relatively low cooling rate of 1000 K/s or less, has high warm processability in a low temperature range owing to its supercooled liquid region of 20K or higher and has excellent fluidity in the liquid state and thereby good castability. The Fe-based multi-element bulk amorphous alloy composition is represented by a formula of FeαCβSiγBxPyMa, in which M is at least one element selected from Ti(titanium), Cr(chromium), Mo(molybdenum), Nb(niobium), Zr(Zirconium), Ta(tantalum), W(tungsten) and V(vanadium), α, β, γ, x, y, and a each represent atomic % of iron(Fe), Carbon(C), silicon(Si), boron(B), phosphorus(P) and the selected metal element, in which α is 100-(β+γ+x+y+a) atomic %, β is 6 atomic % or more and 13 atomic % or less, γ is 1 atomic % or more and 5 atomic % or less, x is 4.5 atomic % or more and 9.5 atomic % or less, y is 3 atomic % or more and 10 atomic % or less and a is 0.1 atomic % or more and 6 atomic % or less.
US07815751B2 Zirconium-vanadium conversion coating compositions for ferrous metals and a method for providing conversion coatings
The invention provides a method and composition for coating a ferrous metal surface with a zirconium/vanadium conversion coating which is substantially free of an organic film forming composition and tannins. The method is a low temperature method which contemplates an aqueous conversion coating composition which is low in phosphates and which comprises zirconium, vanadium, fluoride, as well as phosphate ions in a ratio and a concentration effective for providing a conversion-coated ferrous metal surface.
US07815744B2 Methods for moving a pig through a pipeline using a chemical reaction to generate a high volume of gas
The invention provides a method of moving a pig through pipeline, the method comprising the steps of: a) introducing the pig into the pipeline; b) causing a chemical reaction between two or more reagents to produce at least one reaction product that would be in a gaseous state at STP, wherein the reagents would be in a non-gaseous state at STP; and c) introducing the gaseous reaction product into the pipeline. The invention also provides a method of moving a pig through a pipeline, the method comprising the steps of: a) introducing the pig into the pipeline; b) introducing into the pipeline two or more reagents capable of chemically reacting to produce at least one reaction product that would be in a gaseous state at STP, wherein the reagents would be in a non-gaseous state at STP.
US07815743B2 Method and apparatus for cleaning a turbofan gas turbine engine
Device for cleaning a gas turbine engine, and in particular an engine of turbofan type. The present invention further relates to a method for cleaning such an engine. The device comprises a plurality of nozzles arranged to atomize cleaning liquid in the air stream in an air inlet of the engine up-stream of a fan of the engine. According to the invention, a first nozzle is arranged at a position such that the cleaning liquid emanating from the first nozzle impinges the surfaces of the blades substantially on the pressure side; a second nozzle is arrange at a position such that the cleaning liquid emanating from the second nozzle impinges the surfaces of the blades substantially on the suction side; and a third nozzle is arranged at a position such that the cleaning liquid emanating from the third nozzle passes substantially between the blades and enters an inlet of the core engine. Thereby, the different types of fouling found on the fan and in the core engine compressor of turbofan engine can be removed in an efficient manner.
US07815742B2 Method and device for the internal cleaning of a tank
A method for the internal cleaning of a tank. An oil sump and a gas mixture which is diffused out of the oil sump and has a hydrocarbon-containing gas being present in the crude-oil tank. The gas mixture is sucked away out of the tank and a feed of an inert gas into the tank is permitted. An energy content of the sucked-away gas mixture is determined. The gas mixture is fed to a compressor for compressing the gas mixture, if the energy content of the gas mixture overshoots a limit value, in order to compress the gas mixture in the compressor. The gas mixture is fed to a consumer unit, if the energy content of the gas mixture undershoots the limit value.
US07815734B2 Thin film transistor and method of fabricating the same
Provided are a thin film transistor and method of fabricating the same, in which an amorphous silicon layer is formed on a substrate, a capping layer containing a metal catalyst having a different concentration according to its thickness is formed on the amorphous silicon layer, the capping layer is patterned to form a capping layer pattern, and the amorphous silicon layer is crystallized, such that the density and position of seeds formed at an interface between the amorphous silicon layer and the capping layer pattern is controlled, thereby improving the size and uniformity of grains, and in which polycrystalline silicon of desired size and uniformity is selectively formed at a desired position by one crystallization process, resulting in a thin film transistor having excellent and desired properties.
US07815729B2 Method for recycling construction and demolition fines
The method for recycling construction and demolition fines involves using mixed fines from construction and demolition debris that would otherwise be disposed of at landfills as an ingredient in cement or concrete. The mixed fines contain a plurality of materials selected from the group consisting of asphalt, plastics, ceramics, fiberglass and batt insulation, soil, dust, drywall, wood, plaster, paper, cardboard, dirt. The fines may also contain particles of recyclable materials, such as concrete, bricks, mortar, metals, glass, and the like. The fines may range in size from microns up to 6 inches in at least one direction. The recycler may incorporate the fines into a concrete mix for bulk sale to commercial enterprises, or may himself form precast, lightweight concrete products, such as decorative columns, pedestals and table bases, trim moldings and cornices, door surrounds, etc.
US07815727B2 Titanium oxide for incorporation into thermoplastic resin composition, thermoplastic resin composition, and molded object thereof
A thermoplastic resin composition which comprises (A) 40 to 98 mass % thermoplastic resin and (B) 60 to 2 mass % titanium oxide particles whose surface has been coated with a hydrous oxide and/or oxide of at least one metal selected from the group consisting of aluminum, silicon, zirconium, tin, cerium, titanium, and zinc, wherein the titanium oxide particles contain 80 to 97 mass %, excluding 97 mass %, titanium oxide ingredient and have total content of alkali metal cations and alkaline earth metal cations extractable with pure water of 120 mass ppm or lower. The resin composition is excellent in reflectance and thermal stability in residence during molding into large products.
US07815723B2 Water-based ink system
A no-mess water-based ink including a composition including water, an organic solvent, a coloring agent dissolved in the organic solvent, an emulsifier and a thickening agent for use in conjunction with a specially treated substrate containing a color developer.
US07815722B2 Planar micromachined valve and thermal desorber
This invention provides a pre-concentrator device including an electrostatically operated valve and an electrically heated desorber, the electrostatically operated valve comprising a movable flap or membrane carrying a chemically adsorbing coating, suspended by an elastic element above an orifice in an insulated substrate. The device is constructed by planer processing. The flap or membrane can be deflected towards the substrate to block the flow of gas through the orifice by applying a voltage between the substrate and the membrane. The coating provides an adsorbing surface for a volatile organic compound. The coating may be heated electrically, by applying an alternating voltage between the substrate and the flap, thermally desorbing any adsorbed chemical species. When combined with other similar valves in a stacked assembly, the device may be used in a chemical pre-concentrator with very low dead volume.
US07815711B2 Method for separating gases from a gas mixture and device for applying such a method
Improved method for separating gases from a gas mixture, whereby the gas mixture to be treated is led through a membrane separator (3) by means of a compressor installation (2) and whereby the compressed gas mixture to be treated is cooled in the compressor installation (2), among others in order to separate condensate from the gas mixture, after which, as it leaves the compressor installation (2), it will be re-heated before it ends up in the membrane separator (3), characterized in that, in order to re-heat the gas mixture to be treated as it leaves the compressor installation (2), use is made of the recuperation heat of the compressor installation (2) itself.
US07815709B2 Alkaline electro-hydrometallurgical process for Zn extraction from electric arc furnace dust
An electro-hydrometallurgical process that extracts zinc from electric furnace dust (EAF dust) to produce zinc of high purity and fine particle size, including leaching EAF dust with an alkaline solution to form a zincates solution, separating the liquid and gangue in the zincate solution; inertizing the gangue, purifying the liquid by cementation and separating the liquid from precipitated solids; purifying the zincate solution obtained from the cementation by adsorption, at least partially evaporating the resulting pure solution, bleeding at least a fraction of the concentrated solution obtained; crystallizing at least a fraction of the concentrated solution, electro-depositing zinc from the concentrated solution; and separating washing and drying deposited Zn.
US07815708B2 Process and apparatus for recovery of non-ferrous metals from zinc residues
The invention relates to a process for the separation and recovery of non-ferrous metals from zinc-bearing residues, in particular from residues produced by the zinc manufacturing industry. The process comprises the steps of: —subjecting the residue to a flash or agitated bath fuming step, thereby producing an Fe bearing slag and Zn- and Pb-bearing fumes; and —extracting the Zn- and Pb-bearing fumes and valorising Zn and Pb; characterised in that CaO, SiO2 and MgO are added as a flux before or during the fuming step so as to obtain a final slag composition with: formula (I) all concentrations being expressed in wt %. The invention also relates to a single-chamber reactor for Zn-fuming equipped with one or more submerged plasma torches as heat and gas sources. [ Fe ] [ SiO 2 ] + [ CaO ] [ SiO 2 ] + [ MgO ] 3 > 3.5 ; 0.1 < [ CaO ] [ SiO 2 ] < 1.3 ; ⁢ and 6 < [ SiO 2 ] < 22 , ( I )
US07815702B2 Multi cyclone collector
A multi cyclone collector with an improved structure is disclosed for providing the highest number of second cyclone collector (300) by disposing a plurality of second cyclone collector (300) in a non circular shape (400) arrangement along a first cyclone collector, thereby increasing collecting efficiency.
US07815696B2 Oxidation-stabilized lubricant additives for highly desulfurized fuel oils
The present invention provides an additive for improving the lubricity of fuel oils having a maximum sulfur content of 0.035% by weight. The additive comprises A) at least one partial ester composed of a di- or polyhydric alcohol and unsaturated and optionally also saturated fatty acids whose carbon chain lengths are between 8 and 30 carbon atoms, at least 60% of the fatty acid radicals containing at least one double bond, and B) at least one alkylphenol-aldehyde resin, obtainable by the condensation of (i) at least one alkylphenol having at least one C6-C24-alkyl or C6-C24-alkenyl radical and (ii) at least one aldehyde or ketone, to a degree of condensation of between 2 and 50 alkylphenol units.
US07815695B2 Starch as a fuel or fuel component
New fuels and fuel components comprising starch are provided, as well as novel methods for operating a combustor such as a boiler or an internal combustion engine by feeding a starch fuel to the combustor.
US07815694B2 Production of biofuels and biolubricants from a common feedstock
The present invention is directed to methods and systems for processing triglyceride-containing, biologically-derived oils, wherein such processing comprises conversion of triglycerides to free fatty acids and the separation of these fatty acids by saturation type. Such separation by type enables the efficient preparation of both lubricants and transportation fuels from a common source using a single integrated method and/or system.
US07815689B2 Instrumented prosthetic foot
The present invention discloses an instrumented prosthetic foot for use with an actuated leg prosthesis controlled by a controller, the instrumented prosthetic foot comprising a connector to connect the instrumented prosthetic foot to the leg prosthesis, an ankle structure connected to the connector, a ground engaging member connected to the ankle, at least one sensor for detecting changes in weight distribution along the foot, and an interface for transmitting signals from the sensor to the controller.
US07815688B2 Lap joint for prosthetic foot
Apparatus and methods for a prosthetic foot for attachment to a socket worn by an amputee. In an embodiment, the prosthetic foot comprises a body including a forefoot portion and a heel portion. In addition, the prosthetic foot comprises at least one attachment member extending from the body and conformable to the socket.
US07815680B2 Flexible vertebral implant
A vertebral implant for replacing a biological disk includes a top and bottom plate. The implant further includes flexible coupling that couples together the plates while allowing the same degree of freedom in all axes of motion as the original biological disk.
US07815671B2 Controlled deployment delivery system
A controlled stent-graft deployment delivery system (10 50 or 900) includes a stent-graft (30 or 63), a retractable primary sheath (40) containing the stent-graft in a first constrained diameter configuration, an outer tube (18) within the retractable primary sheath and within the stent-graft, and an inner tube (20) within the outer tube, where the inner tube and the outer tube both axially move relative to the retractable primary sheath and to each other. The system further includes a cap (15) coupled to a distal end of the inner tube and configured to retain at least a portion of a proximal area of the stent-graft in a radially compressed configuration. A distal assembly (100) provides controlled relative axial movement between the outer tube and the inner tube enabling the release of the proximal end (65, 67, 68, and 69) of the stent-graft from the cap and from the radially compressed configuration.
US07815670B2 Method of loading a medical endoprosthesis through the side wall of an elongate member
Medical devices and related systems and methods.
US07815667B2 Power source for an implantable medical device
A power source for an implantable medical device, such as a spinal cord stimulator, has a controlled anterior surface. Preferably, the contoured anterior surface includes a layer of a biocompatible material, such as a polymer. Also preferably, the layer provides a contour generally conforming to the profile of a human buttock. Optionally, a cosmetic implant of generally substantially the same size and shape as the power source is implanted in the opposite buttock as the power source so as to create balance.
US07815664B2 Systems and methods for spinal stabilization with flexible elements
Systems and methods are provided for spinal stabilization with flexible elements and other elements engaged to the vertebrae. Also provided are instruments and methods for insertion of the flexible stabilization elements and other elements and for reduction of displacement between adjacent vertebrae in a minimally invasive surgical approach.
US07815658B2 Ultrasonic treatment apparatus, method of assembling and disassembling ultrasonic treatment apparatus, and ultrasonic treatment system
An ultrasonic treatment apparatus includes a vibrator-assembly which generates ultrasonic vibration, a probe which is detachably mounted to the vibrator-assembly, and has a treatment-portion which performs treatment of a biological tissue in a distal end portion, and a main-body-unit-assembly to which the vibrator-assembly and the probe are detachably mounted, and in which the biological tissue is treated with the treatment-portion when an operator operates the main-body-unit-assembly while the probe is amounted. The main-body-unit-assembly includes a treatment-assembly which has an action-portion in a distal end portion facing the treatment-portion of the probe, and a handle-assembly which is detachably mounted to a proximal end portion of the treatment-assembly, and which brings the action-portion into contact with the treatment-portion of the probe or separates the action-portion from the treatment-portion while the handle-assembly is mounted to the proximal end portion of the treatment-assembly.
US07815655B2 Devices, systems and methods for retracting, lifting, compressing, supporting or repositioning tissues or anatomical structures
Devices, systems and methods for retracting, lifting, compressing, supporting or repositioning tissues, organs, anatomical structures, grafts or other structures within the body of human or animal subjects for the purpose of treating a diseases or disorders and/or for cosmetic or reconstructive purposes and/or for research and development purposes or other purposes.
US07815651B2 Device for immobilizing a primary instrument and method therefor
Devices and methods provide accurate targeting, placement, and/or stabilization of an electrode or other instrument(s) into the brain or other body organ, such as to treat severe tremor or other neurological disorders. Targeting is performed using any form of image-guidance, including real-time MRI, CT, or frameless surgical navigation systems.
US07815650B2 Surgical instrument for moving vertebrae
A surgical instrument extendable through a cannula for moving a first bone portion relative to a second bone portion includes a first portion having a longitudinal axis engageable with a first member connected with to the first bone portion. A second portion is engageable with a second member connected with the second bone portion. The second portion is movable relative to the first portion from a first position toward a second position to move the first and second bone portions away from each other. An actuator connected with the second portion moves the second portion relative to the first portion in a direction extending transverse to the longitudinal axis.
US07815645B2 Methods and apparatus for pinplasty bone resection
Methods and apparatus for performing arthoplasty utilizes a plurality of apertures created in a bone, each aperture having a cross section defined perpendicular to an axis of the aperture that intersects a plane of a resected surface to be created in the bone and also intersects a peripheral rim border that externally delineates the resected surface. A pin feature is inserted into each of the plurality of apertures and the resected surface is created by guiding a cutting tool along at least a line of contact of the pin features. An implant can then be attached to the resected surface.
US07815644B2 Instrumentation and methods for refining image-guided and navigation-based surgical procedures
Automated surgical procedures, including procedures carried out in conjunction with image-guided surgical navigation systems, are improved using tools and techniques to refine bone modifications. A system-level embodiment of the invention includes a memory for storing information relating to a desired modification of a bone, a bone-modification tool, and tracking apparatus for determining the position and orientation of the bone and the bone-modification tool to ensure that the modification performed by the tool corresponds to the desired modification. In the preferred embodiment, the bone-modification tool is used to refine a previously resected surface by a few millimeters or a few degrees to achieve the desired modification. A method of preparing a bone to receive a prosthetic implant according to the invention includes the steps of using an image-guided surgical navigation system to surface a bone, determining if the surface is optimized for the prosthetic implant, and if not, using a finishing tool in conjunction with the image-guided surgical navigation system to refine the surface. These steps may be repeated as desired to further optimize the surface.
US07815642B2 Impact-driven intraosseous needle
An apparatus for penetrating a bone marrow of a bone is provided. The apparatus includes a housing comprising a handle and a trigger mechanism, a spring-loaded assembly comprising a rod and a shaft; and a connector comprising a first end operable to connect to the drive shaft and a second end operable to attach to a penetrator hub. The penetrator hub includes a penetrator operable to access the bone marrow.
US07815640B2 Apparatus and methods for closing vascular penetrations
Apparatus for sealing vascular penetrations comprise a shaft having an electrode or other energy-applying element at a distal end. The shaft is placed in a tissue tract over a blood vessel penetration and located using a locator which engages an inner wall of the blood vessel. Once in position, an anchor is used to hold the shaft, allowing the locator to be removed. Energy is then applied through a distal tip of the shaft in order to induce desiccation and plug formation in a blood pool formed between the distal end of the shaft and the wall of the blood vessel.
US07815634B2 Fluid delivery system and controller for electrosurgical devices
The invention provides a system for treating tissue that includes a power measurement device, a flow rate controller coupled to the power measurement device, and an electrosurgical device configured and arranged to provide radio frequency power and conductive fluid to the tissue, wherein the flow rate controller is configured and arranged to modify a flow rate of the conductive fluid to the tissue, based on signals from the power measurement device. The invention also provides methods and devices for modifying flow rate of conductive fluid to tissue based on measurement of radio frequency power delivered to the tissue.
US07815629B2 Apparatus for treating obesity by extracting food
The present invention is directed to an apparatus and method for treating obesity. A tube is positioned that passes through a patient's abdominal wall into the upper digestive system of the patient. The patient is allowed to carry out his/her everyday affairs including ingesting food. After the patient has ingested food, the food is extracted by pumping it out of the upper digestive system through the tube. The present invention is less invasive than current surgical procedures for reducing weight and allows patients to live a normal and active lifestyle without experiencing adverse side effects.
US07815626B1 Catheter with knit section
A catheter section comprising an elongate tubular member having a proximal end, a distal end, and a passageway defining a lumen extending between the proximal and distal ends. The elongate tubular member includes a knit tubular member and an inner tubular liner in coaxial relationship with the knit tubular member. The catheter section is for use as a distal section in a catheter having a relatively stiff proximal section.
US07815619B2 Receptacle for a male incontinence device
A multi-piece fluid transfer receptacle is used in a male incontinence device. The receptacle includes an outer shell having a first open end adapted for receiving the penis of a user and a second end defining a fluid discharge port. The second end extends beyond the first end a distance sufficient to cover a head of the penis, whereby urine is transferred forwardly from the penis and outwardly from the receptacle through the discharge port. A detachable fluid-management insert is received within the first open end and includes an elongated tongue spaced apart from an interior surface of the outer shell. The tongue forms a backflow barrier between the penis and the outer shell to shield the penis from urine flowing backward towards the user and away from the discharge port.
US07815618B2 Colostomy bag cleaning system
A closed drainage system for irrigating colostomy bags wherein the bag is irrigated and cleaned while in its operable position associated with the person. More specifically, the invention mounts a manifold within the colostomy bag with an access to a water pressure from outside, the manifold providing a spray dispersion of fluid, or water preferably, at the top of the bag and gravity then drips it down through the bag and out the open bottom, preferably with the residue of the bag being washed out by the water and passing into a toilet where the user flushes the bag to completion of cleaning with all residue from the bag passing into the toilet. A water source from the toilet itself, or other suitable water supply, provides the pressured water to the manifold inside the top of the colostomy bag.
US07815617B2 Laminated material and skin contacting products formed therefrom
A laminated material suitable for use in forming skin contacting products is disclosed. The laminated material comprises three distinct layers including a fabric layer, a film layer and an adhesive layer therebetween. The adhesive layer substantially continuously bonds the fabric layer to the film layer.
US07815615B2 Implantable fluid delivery apparatuses and implantable electrode
A cochlear implant system is described. An implantable housing includes an electronics module containing circuitry for developing an electrical stimulation signal for the inner ear, and a fluid channel port for receiving therapeutic fluid for the inner ear. An electrode array includes multiple electrode contacts in electrical communication with the electronics module for stimulating neural tissue of the inner ear with the electrical stimulation signal, and a fluid delivery channel for delivering the therapeutic fluid from the fluid channel port to the inner ear.
US07815614B2 Medical connector with closeable male luer
A luer connector including a housing with first end including a male luer tip and a second end. The connector further includes a rigid valve member having a first opened end and a second closed end and a retaining member configured to couple the valve member and the housing. The housing further includes a rigid conduit positioned within the housing and in fluid communication with the second end of the housing, the rigid conduit adapted to engage the first opened end of the valve member. The housing including a first internal volume when the valve member is in a first position and a second, smaller volume when the valve member is in a second position.
US07815609B2 Disposable infusion device positive pressure filling apparatus and method
An infusion system comprises a disposable wearable infusion device having a body arranged to be adhered to a patient's skin and a reservoir for holding a liquid medicament to be infused into the patient. The infusion system further comprises a filler device arranged to be detachably received by the infusion device and to provide a positive pressure directly to the liquid medicament to transfer a volume of the liquid medicament to the infusion device reservoir.
US07815608B2 High flex introducer assembly
An introducer assembly for accessing a target site in the anatomy of a patient includes a sheath having a proximal end and a distal end, and having a lumen extending therethrough. At least a portion of the sheath distal end has a curved configuration. A tapered dilator has a proximal end and a distal end, and is sized to be received in the sheath lumen. The dilator has a length such that at least a distal tip portion of the dilator extends beyond the distal end of the sheath when the dilator is received in the sheath lumen. The dilator may be formed of polyurethane, and has a stiffness not exceeding a stiffness of the sheath curved portion such that the sheath substantially maintains the curved configuration when the dilator is received in the sheath lumen.
US07815607B2 Insertion device for an insertion head, in particular for an infusion set
An insertion device for an infusion set, the device including a retention means by which the infusion set can be temporarily held on the device and drive means including a pretensionable spring for providing drive energy for an insertion movement of the infusion set, wherein the infusion set is secured by the retention means by clamping when the retention means is in an engage position and can then be moved, with simultaneous pretensioning of the spring, to an insertion movement starting position, wherein the infusion set is already separated from the retention means at the start of the insertion movement, and wherein the infusion set moves through at least part of the insertion movement free of the retention means.
US07815605B2 Emergency medication pump injection system
An emergency multi-medication pump injection system is designed for use in rapidly and automatically calculating and administering multiple medications in an emergency setting. The system includes a compact, portable housing comprising a plurality of medication ports, each port configured to receive a corresponding ampoule containing a corresponding medication. The system further includes at least one pump on or within the housing for dispensing a calculated dosage amount of one or more medications from the ampoules, at least one delivery tube for conveying the medication(s) from the system for delivery to the patient, and safety means for ensuring that each ampoule can only be installed in a port to which the particular ampoule corresponds. The pump injection system may include data inputs for inputting data relating to patient weight, medication concentration, medication dosage, and the like.
US07815601B2 Rapid exchange enteral stent delivery system
Methods of and devices for palliating gastrointestinal strictures using rapid exchange type enteral stent placement catheters. The catheter may include an inner member and an outer member, with the two members being slidable with respect to one another. In various device embodiments, a ramp for directing a guidewire out from within the catheter is provided using portions of the outer member or a shaped mandrel. The inner member may take a number of forms, including a tubular distal portion, a skived or integrally attached elongate midsection, and a proximal portion. A mandrel can be used in a portion proximal of the guidewire ramp, with the mandrel taking one of several disclosed forms.
US07815597B2 System and method of treating stuttering by neuromodulation
Stuttering-treatment techniques using neural stimulation and/or drug delivery. One or more electrodes and/or a catheter are implanted adjacent to sites in the brain. A signal generator and the electrode deliver stimulation to a first site. A pump and the catheter deliver one or more therapeutic drugs to a second site. The first and second sites could be: the supplementary motor area, the centromedian circuit, the dorsomedial nuclei, the lateral prefrontal circuit, or other paramedian thalamic and midbrain nuclei. The stuttering treatment could be performed via periodic transcranial magnetic stimulation. A sensor, located near the patient's vocal folds, can be used for generating a signal responsive to activity of the patient's speech-producing muscles. A controller adjusts one or more stimulation parameters in response to the signal from the sensor.
US07815594B2 Tampon assembly providing proper bodily placement of a pledget
Provided is a tampon applicator having one or more insertion indicators to gauge and/or control the insertion depth of a tampon. The one or more insertion indicators may be located on the tampon applicator barrel, plunger, tampon, removal string, or any combinations thereof. As a result of the one or more insertion indicators, a woman can adjust the insertion depth of the tampon to her body's requirements ensuring leakage protection, comfort, or both.
US07815593B2 Device for introducing an object into a vagina with sanitary finger mounting means
A device for introducing an object into a vagina includes finger mounting means whereby the device is mountable on a user's finger, and a holder which protrudes from the finger mounting means and which is insertable into a user's vagina, the holder being configured to hold an object whilst being inserted into the user's vagina and then release the object once positioned inside the vagina.
US07815590B2 Devices for maintaining patency of surgically created channels in tissue
Devices and methods for altering gaseous flow within a lung to improve the expiration cycle of an individual, particularly individuals having chronic obstructive pulmonary disease. The methods and devices create channels in lung tissue and maintain the patency of these surgically created channels in tissue. Maintaining the patency of the channels allows air to pass directly out of the lung tissue which facilitates the exchange of oxygen ultimately into the blood and/or decompresses hyper-inflated lungs.
US07815589B2 Methods and apparatus for anchoring within the gastrointestinal tract
The present invention relates to an anchor configured for minimally-invasive implantation and sized to remain securely positioned within at least a portion of the gastrointestinal tract of an animal. The anchor includes a radial spring formed from an elongated resilient member shaped into an annular wave pattern about a central axis. The anchor defines a central lumen and provides an outward radial force, while allowing for substantial flexure about its perimeter. The anchor is generally removable, but can include fasteners, such as barbs, to further secure it to the surrounding anatomy. In some embodiments, the anchor includes a connector coupling a fixed portion to a removable portion. Further, the anchor can be used to secure a medical device within the body, such as a flexible sleeve within the intestine.
US07815588B2 Method and device for reversing lines in the procedure of hemodialysis
A device and method for selectively controlling the direction of blood flow to and from the patient during hemodialysis is provided. Specifically, the device and method reverse flow between four fluid lines without changing connections between a patient and a hemodialysis machine. Advantageously, the blood is subjected to minimal stresses as it passes through the switching device.
US07815584B2 Adjustable back support device
An adjustable device is described for applying pressure to an area of a person while substantially eliminating pressure from a prescribed area. The device includes a panel, a first elastic belt, a second elastic belt, a first elastic strap, and a second elastic strap. These elements are connected to one another such that the panel is flanked on one side by the first panel and the first elastic belt and, on the other side, by the second panel and the second belt. Alternate embodiments include several panels disposed side-by-side or on top of one another.
US07815583B2 Body part treatment device with air diverter
A device for applying treatment, or therapy, to a body part directs air efficiently and effectively to the body part by using an air diverter. In particular, a device for treating a body part, such as a massager, has one or more treatment areas positioned to deliver treatment to the body part and an air blower having an air outlet that creates a flow of air in an outward direction from the air outlet. The air diverter is positioned to divert the flow of air to the one or more treatment areas.
US07815580B2 Magnetic guidewire for lesion crossing
The invented guidewire relates to improvements in a magnetically navigable medical guidewire to enable passage through an occluded or partially occluded vessel. The guidewire comprises an elongate wire having a proximal end and a distal end, wherein the distal end further comprises a magnetically responsive element and a helical thread formed on the tip. The distal end of the guidewire may be preferably aligned substantially in the direction of an applied magnetic field, after which the proximal end of the guidewire may be torqued to rotate the threaded tip while remaining aligned with the applied magnetic field and cause the tip to screw through the blockage in the occluded vessel.
US07815579B2 Dynamic integrated lancing test strip with sterility cover
An integrated lancing test strip includes a test strip and a lancet packet coupled to the test strip. The lancet packet includes a sterility sheet enclosing a lancet to maintain the sterility of the lancet and prevent cross-contamination between the test strip and the lancet. The sterility sheet allows the lancet to be sterilized separately from the test strip. The sterility sheet gives the integrated strip a low profile, which is attractive for packaging multiple integrated strips in cassettes, drums, magazines or the like. In one form, the integrated strip is loaded in a meter that includes an adjustment mechanism that adjusts the position of the test strip relative to the skin being sampled. This allows the user to adjust the position of the test strip so as to not apply excessive pressure against skin, which could hamper bleeding from the incision in the skin.
US07815578B2 Methods and apparatus for determining cardiac output
The present invention provides methods and apparatus for determining a dynamical property of the systemic or pulmonary arterial tree using long time scale information, i.e., information obtained from measurements over time scales greater than a single cardiac cycle. In one aspect, the invention provides a method and apparatus for monitoring cardiac output (CO) from a single blood pressure signal measurement obtained at any site in the systemic or pulmonary arterial tree or from any related measurement including, for example, fingertip photoplethysmography.According to the method the time constant of the arterial tree, defined to be the product of the total peripheral resistance (TPR) and the nearly constant arterial compliance, is determined by analyzing the long time scale variations (greater than a single cardiac cycle) in any of these blood pressure signals. Then, according to Ohm's law, a value proportional to CO may be determined from the ratio of the blood pressure signal to the estimated time constant. The proportional CO values derived from this method may be calibrated to absolute CO, if desired, with a single, absolute measure of CO (e.g., thermodilution). The present invention may be applied to invasive radial arterial blood pressure or pulmonary arterial blood pressure signals which are routinely measured in intensive care units and surgical suites or to noninvasively measured peripheral arterial blood pressure signals or related noninvasively measured signals in order to facilitate the clinical monitoring of CO as well as TPR.
US07815577B2 Method and apparatus for locating the fossa ovalis, creating a virtual fossa ovalis and performing transseptal puncture
A method of locating the fossa ovalis in a patient by locating the His bundle, plane of the interatrial septum, and coronary sinus ostium in a patient, and thereafter locating the fossa ovalis on the basis of one or more predetermined distances between the fossa ovalis and the His bundle and the coronary sinus ostium. An apparatus for locating the fossa ovalis and performing a transseptal puncture is also provided.
US07815574B2 Systems and methods for determining blood pressure
Systems and methods for noninvasive assessment of cardiac tissue properties and cardiac parameters using ultrasound techniques are disclosed. Determinations of myocardial tissue stiffness, tension, strain, strain rate, and the like, may be used to assess myocardial contractility, myocardial ischemia and infarction, ventricular filling and atrial pressures, and diastolic functions. Non-invasive systems in which acoustic techniques, such as ultrasound, are employed to acquire data relating to intrinsic tissue displacements are disclosed. Non-invasive systems in which ultrasound techniques are used to acoustically stimulate or palpate target cardiac tissue, or induce a response at a cardiac tissue site that relates to cardiac tissue properties and/or cardiac parameters are also disclosed.
US07815570B2 Non-invasive ultrasonic body contouring
A methodology and system for lysing adipose tissue including directing ultrasonic energy at a multiplicity of target volumes within the region, which target volumes contain adipose tissue, thereby to selectively lyse the adipose tissue in the target volumes and generally not lyse non-adipose tissue in the target volumes and computerized tracking of the multiplicity of target volumes notwithstanding movement of the body.
US07815568B2 Virtual remote monitor, alert, diagnostics and programming for implantable medical device systems
A plurality of co-operative and complementary software programs are implemented in a web-enabled high speed computer system to remotely monitor, manage and modify the operational and functional parameters of a plurality of implanted medical devices (IMDs). The system utilizes virtual electrophysiologist module (VEM), chronic monitoring module (CMM) and prescription program module (PPM) programs to effect specific therapeutic and diagnostic methods for managing the IMDs, remotely on a conditions and real-time basis. The modules enable remote and continuous monitoring, management and maintenance of the IMDs by identifying critical medical events, determining optimal clinical settings and upgrading performance parameters based on prescriptive data. The modules are implemented in a data center having high-speed computers operating in a web-enabled environment. The modules and the IMDs communicate through wireless communications system via a programmer or an interface medical unit (IMD).
US07815564B2 Positioning system for manipulating a channel within a medical device
Embodiments of the invention include a medical device for accessing a patient's body portion and used for diagnosis and treatment of medical conditions. Embodiments of the invention may include a particular endoscopic positioning mechanism for placing an endoscope and an additional treatment device within desired body portions in order to assist in diagnosis and treatment of anatomical diseases and disorders. In particular, a medical device according to an embodiment of the invention includes a positioning mechanism configured for movement through at least two degrees of freedom.
US07815561B2 Brachytherapy applicator
A breast brachytherapy applicator providing a stable semi permanent/permanent in dwelling platform that is configured to replicate anatomically the excised cancer bed and allows for a more precise anatomically correct delivery of limited field radiation treatment. This device may be used to reconstitute a resected tissue space to its pre-operative size and shape to 1) facilitate the accurate and precise delivery of adjunctive breast brachytherapy following breast cancer surgery and 2) prevent/decrease post-operative deformity as a result of surgical resection, whether for benign or malignant disease, and in particular after radiation treatment of malignant disease in the post lumpectomy patient.
US07815560B2 Centrifuge having pivotally supported door
A centrifuge includes a frame, a door, a restricting part, a first spring member, and a second spring member. The frame has an opening on top thereof, when the frame is disposed in an orientation in which the frame is intended to be placed. The door is movably supported on the frame to be capable of opening and closing the opening. The restricting part is provided on the frame and defines a prescribed region. The first spring member has one end pivotally supported on the door, and another end pivotally supported on the frame. The second spring member has one end pivotally supported on the door, and another end that is movable within the prescribed region.
US07815554B2 Weight stack selector
A weight system includes a selector which is movable along weights and may be inserted into a void between adjacent weights.
US07815553B2 Health machine
Provided is a multi-functional health machine which can improve a fixing power of a weight unit in the health machine which can temper various kinds of muscles such as muscles of the upper body and muscles of the waist and the legs, which prevents a connection portion of a support rod which can be selected according to user's physique from seceding due to rotation of a handle portion, and which can reduce a load which is applied to the wrist by making the handle portion rotate according to rotation of the hands to thus make a weight portion placed in a straight line according to the gravitational force of the weight portion. The multi-functional health machine includes: a handle portion (10) on the outer sides of which a pair of grasping rods (11) which a user can hold are respectively formed; a fixing portion (20) to both sides of which the handle portion (10) is fixed; a support rod portion (30) on the upper end of a support rod (31) of which the center of the fixing portion (20) is fixed perpendicularly with the handle portion (10) fixed to the fixing portion (20); and a weight portion (40) in which a plumbing plate (41) of a weight plumb is formed at the lower end of the support rod (31) of the support rod portion (30).