Ocotea alkaloid for relief of anxiety |
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申请号 | US30184172 | 申请日 | 1972-10-30 | 公开(公告)号 | US3900564A | 公开(公告)日 | 1975-08-19 |
申请人 | FERRARI GIORGIO; CASAGRANDE CESARE; | 发明人 | FERRARI GIORGIO; CASAGRANDE CESARE; | ||||
摘要 | Crystalline glaziovine having the formula: AND ITS ACID ADDITION SALTS HAVE PSYCHOTROPIC PROPERTIES USEFUL IN THERAPEUTIC COMPOSITIONS FOR THE RELIEF OF ANXIETY. The alkaloid is obtained by extraction of the bark and leaves of the genus Ocotea (Lauraceae), species glaziovii. |
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权利要求 | 1. A THEREAPEUTIC COMPOSITION IN DOSAGE FORM FOR THE RELIEF OF ANXIETY IN HUMAS COMPRISING, AS ACTIVE PRINCIPLE, A THEREAPEUTIC COMPOUND SELECTED FROM THE GROUP CONSISTING OF THE ALKALIOD GLAZIOVINE HAVING THE FORMULA: 2. The therapeutic composition according to claim 1 consisting of tablets, dragees or capsules containing about 10 mg of said active principle. 3. A method for the relief of anxiety in humans which comprises administering to said humans an effective amount for relief of anxiety of a therapeutic composition comprising, as active principle, a therapeutic compound selected from the group consisting of the alkaloid glaziovine having the formula: 4. The method according to claim 3 which comprises administering a dose amount of from 0.2 to 0.5 mg/kg of body weight. 5. The method according to claim 3 wherein the therapeutic composition consists of tablets, dragees or capsules containing about 10 mg. of said active principle and is administered in a dosage of from 1 to 3 tablets, dragees or capsules. 6. The method according to claim 3 wherein the therapeutic composition consists of ampules containing about 10 mg. of said active principle and is administered in a dosage of from 1 to 3 ampules. 7. The method according to claim 3 which comprises administering a dose amount of from 10 mcg. to about 50 mg/kg of body weight. |
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