Document Document Title
US10781260B2 Anti-OX40 binding proteins
The present disclosure provides anti-OX40 antibodies, and antigen-binding portions thereof. In certain embodiments, the antibodies or fragments thereof, are used for the treatment of cancer.
US10781259B2 Modified antibodies and related compounds, compositions, and methods of use
Provided herein are modified antibodies, compounds used to make them, and intermediates in their synthesis; compositions; formulations and methods, including methods of treating diseases, disorders or conditions, for example, cancer, in humans.
US10781257B2 Bispecific T cell activating antigen binding molecules
The present invention generally relates to novel bispecific antigen binding molecules for T cell activation and re-direction to specific target cells. In addition, the present invention relates to polynucleotides encoding such bispecific antigen binding molecules, and vectors and host cells comprising such polynucleotides. The invention further relates to methods for producing the bispecific antigen binding molecules of the invention, and to methods of using these bispecific antigen binding molecules in the treatment of disease.
US10781256B2 Anti SIRP-α antibodies and bi-specific macrophage enhancing antibodies
Anti-SIRPα antibodies, including multi-specific anti-SIRPα antibodies, are provided, as are related compositions and methods. The antibodies of the disclosure bind to SIRPα and can block the interaction of CD47 on one cell with SIRPα on a phagocytic cell. Antibodies that are bispecific for SIRPα and a second antigen are termed Bi-specific Macrophage Enhancing (BiME) antibodies and have emergent properties. The subject anti-SIRPα antibodies find use in various therapeutic methods. Embodiments of the disclosure include isolated antibodies and derivatives and fragments thereof, pharmaceutical formulations comprising one or more of the anti-SIRPα antibodies; and cell lines that produce the antibodies. Also provided are amino acid sequences of exemplary anti-SIRPα antibodies.
US10781254B2 VISTA regulatory T cell mediator protein, VISTA binding agents and use thereof
The present invention relates to a novel regulatory T cell protein. This protein, designated PD-L3 OR VISTA resembles members of the PD-L1 family, identified a novel and structurally-distinct, Ig-superfamily inhibitory ligand, whose extracellular domain bears homology to the B7 family ligand PD-L1. This molecule is designated as PD-L3 OR VISTA or V-domain Immunoglobulin Suppressor of T cell Activation (VISTA). Expression of VISTA is primarily within the hematopoietic compartment and is highly regulated on myeloid APCs and T cells. Therapeutic intervention of the VISTA inhibitory pathway represents a novel approach to modulate T cell-mediated immunity for the treatment of a wide variety of cancers, e.g., ovarian, bladder cancer and melanomas. Also, VISTA proteins, especially multimeric VISTA proteins and antibodies may be used to suppress T cell immunity in autoimmune disease, allergy, infection and inflammatory conditions, e.g. multiple sclerosis and artritic conditions such as RA.
US10781252B2 Antibodies to TGF-β
The present invention relates to antibody molecules, in particular antibody molecules that bind Transforming Growth Factor beta (TGFβ), and uses thereof. More particularly, the invention relates to antibody molecules that bind and preferably neutralise TGFβ1, TGFβ2 and TGFβ3, so-called “pan-specific” antibody molecules, and uses of such antibody molecules. Preferred embodiments within the present invention are antibody molecules, whether whole antibody (e.g. IgG, such as IgG1 or IgG4) or antibody fragments (e.g. scFv, Fab, dAb).
US10781251B2 Monoclonal antibodies to growth and differentiation factor 15 (GDF-15)
The present invention relates to novel monoclonal anti-human-GDF-15 antibodies, pharmaceutical compositions, kits, methods and uses and the cell lines capable of producing the monoclonal antibodies described herein. The present invention further relates to novel antibodies to human GDF-15 capable of inhibiting cancer growth.
US10781247B2 Targeted therapeutics based on engineered proteins that bind EGFR
The present invention relates to single domain proteins that bind to epidermal growth factor receptor (EGFR). The invention also relates to single domain proteins for use in diagnostic, research and therapeutic applications. The invention further relates to cells comprising such proteins, polynucleotide encoding such proteins or fragments thereof, and to vectors comprising the polynucleotides encoding the innovative proteins.
US10781246B2 Compositions and methods for anti-staphylococcal biologic agents
The present disclosure is directed to staphylococcal leukotoxin and hemolysin binding molecules and fusion constructs. The present disclosure is further directed to methods of treating, preventing, and diagnosing staphylococcal infection in a subject using the binding molecules and fusion constructs described herein.
US10781242B2 Interleukin-2 fusion proteins and uses thereof
The present invention relates to interleukin-2 fusion proteins. More specifically, the invention provides, in part, fusion proteins that include a interleukin-2 protein moiety joined to a Bcl-2 family member protein moiety.
US10781240B2 EPHA2 t-cell epitope agonists and uses therefore
EphA2 T-cell epitope are provided herein. The epitopes include peptides corresponding to specific fragments of human EphA2 protein containing one or more T-cell epitopes, and conservative derivatives thereof. The EphA2 T-cell epitopes are useful in an assay, such as an ELISPOT assay, that may be used to determine and/or quantify a patient's immune responsiveness to EphA2. The epitopes also are useful in methods of modulating a patient's immune reactivity to EphA2, which has substantial utility as a treatment for cancers that overexpress EphA2, such as renal cell carcinoma (RCC). The EphA2 epitopes also can be used to vaccinate a patient against EphA2, by in vivo or ex vivo methods.
US10781236B2 Bacteriocin composition and method
The present invention provides a multi-peptide composition with antibacterial activity comprising at least 3 peptides with the sequences as set forth in SEQ ID NO:1, 2 or 3 (or related sequences), respectively, in which the SEQ ID NO:1 sequence (or its related sequence) comprises at least two tryptophan residues. In particular the invention provides a new bacteriocin, Garvicin KS. The invention also provides compositions and host cells containing such antibacterial compositions. Uses of the antibacterial composition in treating bacterial infection and products treated with the antibacterial composition are also provided.
US10781235B2 Multivalent ligand-lipid constructs
Water dispersible, multivalent ligand-lipid constructs that spontaneously and stably incorporate into membranes are disclosed.
US10781234B2 Macrocyclic compounds and methods of making and using same
Provided are macrocyclic compounds having one or more transmembrane segment-thermoresponsive segment moiety. Also provided are dimers comprising two macrocyclic units, which have one or more transmembrane segment-thermoresponsive segment moiety, joined by one or more crosslinking moieties. The macrocyclic compounds and macrocyclic units have a macrocyclic backbone comprise alternating alpha amino acid and meta-aminobenzoic acid moieties. The macrocyclic compounds and dimers can be used to deliver a cargo (e.g., cell-interacting agents such as, for example, drugs and cryoprotectants) to, for example, an organ, tissue, or an individual, A cargo may be encapsulated in lipid vesicles.
US10781227B2 Application of metal complexes in anti-tumor and anti-bacterial therapy
The present invention provides biologically active compounds and methods to obtain biologically active compounds that can be used as photosensitizers for diagnostic and therapeutic applications, particularly for PDT of cancer, infections and other hyperproliferative diseases, fluorescence diagnosis and PDT treatment of non-tumorous indications such as arthritis, inflammatory diseases, viral or bacterial infections, dermatological, ophthalmological or urological disorders. As the compounds exhibit also toxicity against targets (tumor cells, bacteria, inflammation-related cells) without light these biologically active compounds may also be used for the light-independent treatment of such indications. Preferred embodiments of the present invention consist of methods to synthesize metal or half-metal complex structures incorporating one or more substituted 2,3,5,6-tetrafluorophenyl-dipyrromethene (2,3,5,6-tetrafluorophenyldipyrrin) units. These dipyrromethenes (dipyrrins) can carry a variety of different substituents in the 4-position enabling a fine tuning of their biological or amphiphilic/hydrophilic properties. Another object of the present invention is to provide amphiphilic compounds with a higher membrane affinity and increased efficacy.
US10781223B2 Polymer materials with silane-based transfer reagents
Radically polymerizable silane according to the general formula I in which R1 is a linear or branched aliphatic C1-C9-alkyl radical, phenyl or alkylated phenyl radical, R2, R3 independently of each other in each case are absent or are a linear or branched aliphatic C1-C20-alkylene radical, which can be interrupted by S or O atoms, R4, R5, R6 independently of each other in each case are —Cl, —O—CH3, —O—C2H5, —CH3 or —C2H5, X is CH2 or O, Y is absent, or is O or NR′, wherein R′ is H or a C1-5-alkyl radical, and Z is absent, or is O, NR″, —CO—O—, —CO—NR″—, —O—CO—O—, —O—CO—NR″—, or —NR″—CO—NR″—, wherein R″ is H or a C1-5-alkyl radical and wherein the radicals R2 and R3 cannot be absent at the same time and Z is absent if R2 or R3 is absent, polycondensates based thereon and fillers surface-modified therewith.
US10781221B2 Preparation of aromatic-substituted silylamines by the dehydrogenative coupling of aromatic-substituted amine N—H and Si—H bonds
The present disclosure is directed at methods of forming an N—Si silyl bond, the method comprising contacting an organic substrate comprising an aromatic amine having at least one N—H bond with a mixture comprising of (a) at least one hydrosilane or hydrosiloxane and (b) at least one hydroxide or alkoxide, under conditions sufficient to form the N—Si bond. The disclosure is further directed to the compositions involved in these methods and the products that result therefrom.
US10781214B2 Kinase inhibitor against wild-type and mutant EGFR
The present application provides a compound of Formula (I) as an inhibitor against wild-type EGFR and/or mutant EGFR, which may be used for treating human non-small cell lung cancer individually or in combination with other therapeutic agent(s). The compound of Formula (I) of the present application may be used for treating patients of drug-resistant human non-small cell lung cancer harboring wild-type EGFR and/or EGFR T790M mutation and/or EGFR L858R mutation and/or EGFR delE746_A750 mutation.
US10781213B2 Methods for preparing bis-tetrahydroisoquinoline-containing compounds
(−)-Jorumycin, ecteinascidin 743, saframycin A and related compounds, methods of preparing the same, formulations comprising the compounds, and methods of treating proliferative diseases with the same are provided.
US10781212B2 2,6-diamino pyridine compounds
The present invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof, and the use of compounds of Formula I for treating metabolic conditions, such as type 2 diabetes mellitus, heart failure, diabetic kidney disease, and non-alcoholic steatohepatitis.
US10781210B2 Nitrogen-containing heterocycle and carbocycle derivatives having TrkA inhibitory activity
The present invention provides a compound having TrkA inhibitory activity, or a pharmaceutically acceptable salt thereof. The present invention relates to a compound represented by Formula (I): wherein ═X is ═O or the like, R5 and R5A are hydrogen atoms or the like, —A— is —NR1— or the like, B is substituted or unsubstituted aromatic carbocyclyl or the like, R1 is substituted or unsubstituted alkyl or the like, R2 is a hydrogen atom or the like, —W— is —CH2— or the like, —WA— is —CH2— or the like, R13 is substituted or unsubstituted aromatic carbocyclyl or the like, R14 is substituted or unsubstituted aromatic heterocyclyl or the like, R15 is substituted or unsubstituted alkyl or the like, or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition containing the same.
US10781209B2 1H-pyrrolo[2,3-c]pyridin-7(6H)-ones and pyrazolo[3,4-c]pyridin-7(6H)-ones as inhibitors of BET proteins
The present invention relates to substituted pyrrolopyridinones and substituted pyrazolopyridinones which are inhibitors of BET proteins such as BRD2, BRD3, BRD4, and BRD-t and are useful in the treatment of diseases such as cancer.
US10781199B2 Crystalline 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione dihydrate, compositions and methods of use thereof
Provided herein is a crystalline 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione dihydrate. Pharmaceutical compositions comprising the crystalline 4-amino-2-(2,6-dioxopiperidine-3-yl)isoindoline-1,3-dione dihydrate are also disclosed.
US10781196B2 Integrated process for direct saccharification and dehydration of intact biomass to furfurals
A method of converting a lignocellulosic biomass to monosaccharides, and optionally further converting the monosaccharides to one or both of furfural and HMF, includes contacting the biomass with a reactive liquid phase comprising LiBr, H2SO4, and water, wherein H2SO4 preferably constitutes at most 1.0 wt %, more preferably at most 0.5 wt %, and most preferably at most 0.1 wt % of the reactive liquid phase, and water preferably constitutes at most at most 60 wt %, more preferably at most 50 wt %, and most preferably at most 30 wt % of the reactive liquid phase.
US10781195B2 Process to produce 5-hydroxymethylfurfural (HMF) from carbohydrates using a solvent system containing water and a polar aprotic solvent
A method to produce 5-hydroxymethylfurfural (HMF) from C6 carbohydrates. The method includes the steps of reacting a reactant comprising at least one C6 carbohydrate, in a reaction mixture comprising at least about 5% (v/v) water, a polar, aprotic solvent, and an acid, for a time, at a temperature, and at a hydrogen ion concentration wherein at least a portion of the C6 carbohydrate present in the reactant is converted to 5-hydroxymethyl furfural (“HMF”).
US10781192B2 Process of preparing a peptide epoxyketone immunoproteasome inhibitor, and precursors thereof
Disclosed herein are methods for preparing [(2S,3R)—N-[(2S)-3-(cyclopent-1-en-1-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-hydroxy-3-(4-methoxyphenyl)-2-[(2S)-2-[2-(morpholin-4-yl)acetamido]propanamido]propanamide (compound “G”): and precursors thereof.
US10781191B2 Acesulfame potassium compositions and processes for producing same
Improved processes for producing high purity acesulfame potassium. In one embodiment, the process comprises the steps of contacting a solvent, e.g., dichloromethane, and a cyclizing agent, e.g., sulfur trioxide, to form a cyclizing agent composition and reacting an acetoacetamide salt with the cyclizing agent in the composition to form a cyclic sulfur trioxide adduct. The contact time is less than 60 minutes. The process also comprises forming from the cyclic sulfur trioxide adduct composition a finished acesulfame potassium composition comprising non-chlorinated, e.g., non-chlorinated, acesulfame potassium and less than 35 wppm 5-halo acesulfame potassium, preferably less than 5 wppm.
US10781190B2 Acesulfame potassium compositions and processes for producing same
A process for producing acesulfame potassium, the process comprising the steps of providing a cyclizing agent composition comprising a cyclizing agent and a solvent and having an initial temperature, cooling the cyclizing agent composition to form a cooled cyclizing agent composition having a cooled temperature less than 35° C., reacting an acetoacetamide salt with the cyclizing agent in the cooled cyclizing agent composition to form a cyclic sulfur trioxide adduct composition comprising cyclic sulfur trioxide adduct; and, forming from the cyclic sulfur trioxide adduct in the cyclic sulfur trioxide adduct composition the finished acesulfame potassium composition comprising non-chlorinated acesulfame potassium and less than 39 wppm 5-chloro-acesulfame potassium. The cooled temperature is at least 2° C. less than the initial temperature.
US10781189B2 1,2,4-Oxadiazole and thiadiazole compounds as immunomodulators
The present invention relates to 1,2,4-oxadiazole compounds of formula (I) and their use to inhibit the programmed cell death 1 (PD-1) signaling pathway and/or for treatment of disorders by inhibiting an immunosuppressive signal induced by PD-1, PD-L1 or PD-L2.
US10781188B2 Contrast agents
The present invention relates to new class of functionalized macrocycles capable of chelating paramagnetic metal ions, their chelated complexes with metal ions and the use thereof as contrast agents, particularly suitable for Magnetic Resonance Imaging (MRI) analysis.
US10781185B2 Heterocyclic compounds for the inhibition of PASK
Disclosed herein are new heterocyclic compounds and compositions and their application as pharmaceuticals for the treatment of disease. Methods of inhibiting PAS Kinase (PASK) activity in a human or animal subject are also provided for the treatment of diseases such as diabetes mellitus.
US10781175B2 Solid supports and phosphoramidite building blocks for oligonucleotide conjugates
Novel non-nucleoside solid supports and phosphoramidite building blocks for preparation of synthetic oligonucleotides containing at least one non-nucleosidic moiety conjugated to a ligand of practical interest and synthetic processes for making the same are disclosed. Furthermore, oligomeric compounds are prepared using said solid supports and phosphoramidite building blocks, preferably followed by removal of protecting groups to provide oligonucleotides conjugated to ligands of interest.
US10781172B2 Catalysts and methods for enantioselective conjugate additions of amines to unsaturated electrophiles
Disclosed are complexes and methods of using the complexes as catalysts for addition of amines to unsaturated electrophiles, as well as novel compounds produced by the disclosed complexes and methods. The disclosed methods may utilize the disclosed complexes as catalysts for adding unprotected primary amines and secondary amines to unsaturated electrophiles in an enantioselective manner to produce novel compounds which may include amino substituted succinimide compounds.
US10781169B2 Method of synthesis of an ionizable cationic lipid
Disclosed herein is a lipid composition comprising a compound having the formula IA, or a pharmaceutically acceptable salt thereof, wherein R3 is a linear or branched alkylene of 1-6 carbons; R4 and R5 are the same or different, each a hydrogen, or a linear or branched alkyl of 1-6 carbons; and L3 is a bond or an alkane of 1-6 carbons.
US10781167B2 Urea process with high-temperature stripping
A shell-and-tube stripper for carbamate decomposition and ammonia recovery from a urea solution comprising a bundle of heated tubes, said tubes being fed with said urea solution and carbon dioxide as stripping medium, the urea solutions forming a liquid falling film on the internal surface of the tubes and the carbon dioxide forming a counter-current gaseous flow; said tubes comprise an external layer made of super austenitic or super duplex stainless steel and an internal layer made of zirconium, said internal layer reaching temperatures higher than 220° C.
US10781161B2 Therapeutic DNP derivatives and methods using same
The present invention includes DNP derivatives that are useful for preventing or treating a metabolic disease or disorder in a subject in need thereof. In certain embodiments, the subject is further administered at least one additional therapeutic agent.
US10781155B2 Method for producing acetic acid
Provided are a method and an acetic acid production method, each of which can effectively restrain or prevent local corrosion of an inner wall of a process unit and/or line and can lower a formic acid concentration in an acetic acid product. The method produces acetic acid by a process including (1) a reaction step and (A) a separation step. In the reaction step (1), methanol is carbonylated with carbon monoxide in the presence of a catalytic system, acetic acid, methyl acetate, and water, where the catalytic system includes a metal catalyst and methyl iodide. In the separation step (A), the reaction mixture resulting from the reaction step is separated, using at least one selected from evaporators and distillation columns, into a stream containing the catalyst, an acetic acid stream rich in acetic acid, and a stream rich in lower-boiling components as compared with the acetic acid stream. In this method, an oxygen concentration is controlled by at least one of (a) controlling the oxygen concentration in a gaseous phase in the process to less than 7 percent by volume, and (b) controlling the oxygen concentration in a liquid phase in the process to less than 7×10−5 g/g. In addition, a formic acid concentration in the liquid phase in the process is controlled to 500 ppm by mass or less. Thus, the formation of at least one of iodine and formic acid is restrained.
US10781151B2 Process for producing hydrofluoroolefin
A method for producing a hydrofluoroolefin is provided. The formation of by-products of an over-reduced product having hydrogen added to a material chlorofluoroolefin and an over-reduced product having not only chlorine atoms but also fluorine atoms in the chlorofluoroolefin replaced with hydrogen atoms is suppressed in the method. The method includes reacting a specific chlorofluoroolefin with hydrogen in the presence of a catalyst supported on a carrier to obtain the hydrofluoroolefin. The catalyst is a catalyst composed of an alloy containing at least one platinum group element of palladium and platinum, and at least one second element of copper, gold, lithium, potassium, silver, zinc, tin, lead, and bismuth.
US10781150B2 Molecular sieves mediated unsaturated hydrcarbon separation and related compositions, materials, methods and systems
Described herein are compositions having an eight-membered monocyclic unsaturated hydrocarbon, methods and system to separate the eight-membered monocyclic unsaturated hydrocarbon at from a hydrocarbon mixture including additional nonlinear unsaturated C8H2m hydrocarbons with 4≤m≤8, by contacting the hydrocarbon mixture with a 10-ring pore molecular sieve having a sieving channel with a 10-ring sieving aperture with a minimum crystallographic free diameter greater than 3 Å and a ratio of the maximum crystallographic free diameter to the minimum crystallographic free diameter between 1 and 2, the molecular sieve having a T1/T2 ratio≥20:1 wherein T1 is an element independently selected from Si and Ge, and T2 is an element independently selected from Al, B and Ga, the 10-ring pore molecular sieve further having a counterion selected from NH4+, Li+, Na+, K+ and Ca++.
US10781147B2 Methods for toluene recovery from linear alpha olefin production
The present disclosure provides a method of flushing a reactor used in the production of linear alpha olefins, including flushing reactor equipment with toluene from a solvent source, wherein the reactor contains by-products from the production of the linear alpha olefins, wherein the by-products include a polymeric material. The flushed toluene containing polymeric material is directed into a separation train containing the linear alpha olefins, wherein the polymeric material is soluble in at least one of the linear alpha olefins. The linear alpha olefins can be separated from the toluene and the toluene is recycled to the solvent source.
US10781144B2 Process and device for processing an inorganic nutritive iron composition
Plant fertirrigation method comprising the formation of a series of mother solutions, the feeding of each of the mother solutions into a dilution system in order to form a fertirrigation solution, the supply to a fertirrigation device by means of a transfer device, supplying said fertirrigation device with said fertirrigation solution, and an addition of iron and of at least one polyphosphate.
US10781143B2 Method and plant for treatment of organic waste
The present invention relates to methods and plants for the treatment of an organic waste material, wherein waste is subjected to anaerobic fermentation in a biogas digester; effluent is mechanically separated from the biogas digester into a concentrated fraction and a liquid fraction; the liquid fraction is heated to a high temperature below the boiling point of the liquid; the heated liquid is introduced to a flash column to partially remove volatile carbon dioxide, the pH of the liquid is elevated and ammonia is removed from the liquid.
US10781140B2 Method and apparatus for the curing of composite material by control over rate limiting steps in water removal
The invention encompasses equipment used to condition a recirculating gas stream in order to cure a CO2 Composite Material (CCM) and processes that use such equipment to cure the CCM. The gas conditioning equipment allows for a process that controls, reduces or eliminates the rate-limiting steps associated with water removal during the curing of a composite material. The equipment may include, but will not be limited to, control over the temperature, relative humidity, flow rate, pressure, and carbon dioxide concentration within the system; which includes the conditioning equipment, any vessel containing the CCM, and the material itself. Flow rate control can be used as a means to achieve uniformity in both gas velocity and composition.
US10781137B2 Fiberglass material manufacture method comprising steps of sizing and desizing, and facility suitable for implementing said method
The invention relates to a fiberglass material manufacture method and facility, were in molten glass is converted into fiberglass material via the steps of spinning, drawing, sizing, and collecting, followed by a step of producing a resulting fiberglass material that is then subjected to thermal desizing. The fumes from the melting furnace are used to preheat a combustion reagent from the melting furnace in two steps: a first step in which air is heated via heat exchange with the fumes, and a second step in which the combustion reagent is preheated via heat exchange with the hot air, the air then being used in the step of desizing the fiberglass material.
US10781136B2 Glass with single reinforced layer and preparation method thereof
The present invention relates to glass with a single reinforced layer, comprising a glass body and the single reinforced layer formed in a surface of the glass body. The compressive stress of the single reinforced layer trends to decrease non-linearly from the surface of the glass body to the interior of the glass body. The compressive stress curve of the single reinforced layer has an inflection point. The gradient of a first curve section in front of the inflection point is greater than the gradient of a second curve section behind the inflection point. The overall refractive index of the single reinforced layer trends to decrease non-linearly from the surface of the glass body to the interior of the glass body. The refractive index curve of the single reinforced layer has at least two inflection points. Furthermore, a method for preparing the glass with a single reinforced layer is provided.
US10781135B2 Strengthening variable thickness glass
Apparatus, systems and methods for increasing the strength of glass are disclosed. The use of multi-bath chemical processing for a glass article can facilitate controlled chemical strengthening. Through multi-bath (or multi-step) chemical processing, differing levels of strengthening can be achieved for different portion of glass articles. The multi-bath chemical processing can be achieved through the use of successive chemical baths. Accordingly, glass articles that have undergone multi-bath chemical processing are able to be not only thin but also sufficiently strong and resistant to damage. The strengthened glass articles are well suited for use in consumer products, such as consumer electronic devices (e.g., portable electronic devices). In one embodiment, the glass member can pertain to a glass cover for a housing of an electronic device.
US10781131B2 White, opaque, β-spodumene glass-ceramic articles with inherent damage resistance and methods for making the same
Crystallizable glasses, glass-ceramics, IXable glass-ceramics, and IX glass-ceramics are disclosed. The glass-ceramics exhibit β-spodumene ss as the predominant crystalline phase. These glasses and glass-ceramics, in mole %, include: 60-75 SiO2; 10-18 Al2O3; 5-14 Li2O; and 4.5 B2O3. The glass-ceramics also have a Vickers initiation crack threshold of at least about 25 kgf.
US10781128B2 Curved display device and manufacturing method thereof
A method of manufacturing the curved display device includes a process of manufacturing a cover glass assembly by attaching a transparent polymer film to the back surface of a thin film glass of a flat plate, a process of bending and inserting the cover glass assembly into a curved cavity of a mold and then molding an edge member so as to be integrated with an edge portion of the cover glass assembly to maintain the cover glass assembly in a bent state, and a process of attaching a flexible display panel to the back surface of the cover glass assembly in a curved state after molding the edge member. The curved display device includes a cover glass assembly, an edge member to maintain the cover glass assembly in a bent state, and a flexible display panel attached to the back surface of the cover glass assembly.
US10781123B2 Multi-stage wastewater treatment and hydroponic farming device
A Multi-Stage Wastewater Treatment and Hydroponic Farming Device comprises a compact basin, a moving bed biofilm reactor (MBBR), a modified wetland material, at least one microbial fuel cell (MFC) and a distributor. The MBBR and modified wetland material are disposed within the basin. Openings in the distributor retain hydroponic plants. In one example, wastewater enters through the MBBR which performs primary treatment of wastewater. Treated wastewater is further treated by modified wetland material and the MFC which generates electrical energy that supplies other components. Treated wastewater is pumped through the distributor and processed by hydroponic plants which extract growth inducing nutrients from the treated wastewater. Resultant water treated by the device is selectively recycled through various parts of the device or extracted from the device and used for other purposes. In one example, multiple devices are deployed in an area thereby providing self-sustaining, efficient water treatment and farming functionality.
US10781121B2 Hydro-kinetic reactor tank
A high efficiency reactor tank is designed to remove pollutants from domestic wastewater. Embodiments of the tank can include at least one integrally-molded internal wall that divides the tank into at least two chambers and which can be a one-piece tank with at least one top riser. The internal wall can be integrally-molded within the tank as well as separately formed and inserted into the tank. The tank can be roto-molded (i.e., rotationally-molded) using plastic or cast/made from concrete, steel, fiberglass and/or similar structural materials. The reactor tank can be applied to remove suspended solids, BOD, ammonia, nitrate, TKN, phosphorus, pathogens and other pollutants from the wastewater.
US10781120B2 Heaterless hydrolytic degritter
The present invention relates to improving the results of anaerobic digestion of organic waste especially animal manure such as chicken manure by removing the grit in the waste by digesting the waste in a slurry at a temperature of about 50° C. or more for a period of time sufficient for the grit to settle out of the slurry.
US10781119B2 Membrane assembly for supporting a biofilm
A cord for supporting a biofilm has a plurality of yarns. At least one of the yarns comprises a plurality of hollow fiber gas transfer membranes. At least one of the yarns extends along the length of the cord generally in the shape of a spiral. Optionally, one or more of the yarns may comprise one or more reinforcing filaments. In some examples, a reinforcing yarn is wrapped around a core. A module may be made by potting a plurality of the cords in at least one header. A reactor may be made and operated by placing the module in a tank fed with water to be treated and supplying a gas to the module. In use, a biofilm covers the cords to form a membrane biofilm assembly.
US10781118B2 Recirculating, purifying, disinfecting, cooling, decontaminating feedback controlled water system for drinking water and other uses to improve health and well being of animals and humans
A water purification system provides clean water for the consumption by livestock by using a continuously recirculating water loop. Optionally, a circulating pump moves the water within the water loop in a flow direction. A water supply inlet is fluidically connected to the water loop to provide additional water. A particle filter system (or systems) is fluidically connected in series and removes dissolved solids or particulates within the water. An ozone purification system and/or with the addition of other antimicrobial or purification agents is fluidically connected in parallel to a portion of the continuously recirculating feedback monitored and control water loop. The ozone purification system is disposed downstream of the particle filter system and RO (or similar) system in relation to the flow direction. A feeding station is connected in series with the continuously recirculating water loop disposed downstream of the ozone purification system in relation to the flow direction.
US10781117B2 Flocculation of high-solids mineral slurries
The present invention relates to a method of dewatering an aqueous mineral suspension comprising introducing into the suspension a flocculating system comprising a mixture of polyethylene glycol and polyethylene oxide polymers, in particular a mixture of one or more low molecular mass polyethylene glycol with one or more high molecular mass polyethylene oxide. Said mixture of polyethylene glycol and polyethylene oxide polymers is useful for the treatment of suspensions of particulate material, especially waste mineral slurries. The invention is particularly suitable for the treatment of tailings and other waste material resulting from mineral processing, in particular, the processing of oil sands tailings.
US10781116B2 Devices, systems and methods for treatment of liquids with electromagnetic fields
Devices, systems and methods for applying electromagnetic fields to liquids, such as water, to treat unwanted material in the liquid are disclosed. Such devices, systems and methods may include a cylindrically shaped, water-immersible probe configured to generate electromagnetic fields that are effective to treat unwanted materials, such as scale, and microbes in the water.
US10781111B2 Method and system for treating wastewater
Methods and systems for treating brine to produce distilled water and dried NaCl are disclosed. The brine enters a crystallization plant and is heated. Once heated, the brine is circulated to an evaporator. The evaporator increases the concentration of NaCl in the brine to a point about the super saturation level. Once above the super saturation level, NaCl crystals are formed. The larger crystals are circulated to a centrifuge for drying and the smaller crystals are recirculated through the evaporator for continued growth. The NaCl crystals are dried in the centrifuge.
US10781107B2 Mineral slurries
Stable mineral slurries and methods of making stable mineral slurries.
US10781104B2 Composite substrate, method for forming nanocarbon film, and nanocarbon film
Provided is a composite substrate which is provided with: a single crystal silicon carbide thin film 11 having a thickness of 1μm or less; a handle substrate 12 which supports the single crystal silicon carbide thin film 11 and is formed from a heat-resistant material (excluding single crystal silicon carbide) having a heat resistance of not less than 1,100° C.; and an intervening layer 13 which has a thickness of 1μm or less and is arranged between the single crystal silicon carbide thin film 11 and the handle substrate 12, and which is formed from at least one material selected from among silicon oxide, silicon nitride, aluminum oxide, aluminum nitride, zirconium oxide, silicon and silicon carbide, or from at least one metal material selected from among Ti, Au, Ag, Cu, Ni, Co, Fe, Cr, Zr, Mo, Ta and W. This composite substrate according to the present invention enables the formation of a nanocarbon film having few defects at low cost.
US10781100B2 Fuel cell system
A fuel cell system includes a reformer and a plurality of fuel cells of solid oxide. The reformer reforms raw fuel to generate fuel gas. The plurality of fuel cells generates electric power by using the fuel gas and oxidant gas. The plurality of fuel cells is arranged in the up-down direction and the right-left direction. The reformer has a cell facing face that faces any of the plurality of fuel cells in the back-and-forth direction. This configuration improves temperature uniformity among the plurality of fuel cells, and as a result, suppresses or prevents a decrease in the power generation efficiency of the fuel cell system.
US10781098B2 Method of manufacturing semiconductor structure
A method of manufacturing a semiconductor structure includes receiving a first substrate including a first dielectric layer disposed over the first substrate and a first conductive structure surrounded by the first dielectric layer; receiving a second substrate including a second dielectric layer disposed over the second substrate and a second conductive structure surrounded by the second dielectric layer; bonding the first dielectric layer with the second dielectric layer; and bonding the first conductive structure with the second conductive structure.
US10781097B2 Micromechanical component
A micromechanical component, having a carrier wafer having at least one micromechanical structure that is situated in a cavern; a thin-layer cap situated on the carrier wafer, by which the cavern is hermetically sealed; and a cap wafer situated on the thin-layer cap in the region of the cavern having the micromechanical structure, the cap wafer hermetically sealing a region of the thin-layer cap above the cavern.
US10781095B2 Molded lead frame sensor package
Examples provided herein are associated with a molded lead frame of a sensor package. An example sensor package may include a molded lead frame that includes an opening in the molded lead frame, wherein the opening extends from a mount-side of the molded lead frame to a chip-side of the molded lead frame, wherein the chip-side of the molded lead frame is opposite the mount-side; and a sensor mounted to the chip-side of the molded lead frame.
US10781093B2 Liquid dispenser for dispensing water and a flavored beverage
A liquid dispensing apparatus for dispensing water and a flavored beverage. The dispensing apparatus may dispense chilled drinking water, hot drinking water and/or ambient temperature drinking water. The dispensing apparatus may further dispense a chilled, ambient temperature and/or hot flavored beverage. The flavored beverage may be coffee, tea, hot chocolate or another flavored beverage. The dispensing apparatus may include a replaceable five (5) gallon water bottle stored in a lower portion of the dispensing apparatus or an external source of water. Preferably, the liquid dispensing apparatus dispenses chilled drinking water and hot coffee from a replaceable five (5) gallon water bottle stored in a lower portion of the dispensing apparatus wherein the replaceable five (5) gallon water bottle is stored in an upright orientation, i.e., the discharge port of the replaceable five (5) gallon water bottle is oriented above a bottom of the replaceable five (5) gallon water bottle.
US10781091B2 Cover removal system for use in controlled environment enclosures
An apparatus and method are presented for removing container covers within a controlled environment enclosure without using gloves. The apparatus comprises an articulated arm apparatus and a gripping apparatus and can further comprise a controller. The articulated arm apparatus can be configurable for holding and moving a container in three dimensions; and the gripping apparatus can be configured for gripping a container cover sealing the container. The method comprises moving the container using the articulated arm apparatus while holding a gripping area of the container cover substantially stationary using the gripping apparatus. The apparatus can further comprise a sensor configured for supplying information to the controller for determining the location of the container cover gripping area and an orientation of the container cover. The method can further comprise inspecting the container cover using the sensor. The container can be moved along a path and within a space determined by the controller.
US10781090B2 Articulated boom telehandler
A telehandler includes a frame assembly, a series of tractive elements rotatably coupled to the frame assembly, a boom assembly, and an actuator selectively reconfigurable between a locked configuration and an unlocked configuration. The boom assembly includes a lower boom section having a proximal end pivotably coupled to the frame assembly, an intermediate boom section pivotably coupled to a distal end of the lower boom section, and an upper boom section having a proximal end pivotably coupled to the intermediate boom section and a distal end configured to be coupled to an implement. The boom assembly is configured to move freely when the actuator is in the unlocked configuration. In the locked configuration, the actuator is positioned to couple the intermediate boom section to the frame assembly such that the actuator limits rotation of the lower boom section relative to the frame assembly.
US10781087B2 Trailer mounted capstan winch
A portable winch system includes a frame, a pair of wheels, a motor that is secured to the frame; and a capstan that is secured to the frame and that is rotatable via the motor. A rope is wound about the capstan in a manner that enables a user to grasp a tail end of the rope and induce friction between the capstan and the portion of the rope that is wound about the capstan. A tow end of the rope is attachable to an object to be pulled by the winch. An input guide attached to the frame is configured to receive the rope and direct the rope toward the capstan as the object is pulled toward the winch. An alignment guide attached to the frame is configured to contact the rope and align the rope about the capstan as the rope is wound about the capstan.
US10781084B2 Support for a crane
The present disclosure relates to a support for a crane, in particular for a mobile crane, having at least two first support beams and two second support beams that are each arranged pairwise at mutually oppositely disposed sides of the support.
US10781081B2 Tower crane for erecting a wind turbine, and method for erecting said tower crane
A rotating tower crane for erecting a wind turbine, having a tower and a tower substructure, which is connected to the tower and is intended for supporting the tower, wherein the tower substructure has a supporting cross frame, which has three or more, preferably four, legs, extending from the tower. It is proposed that each leg has fastened on it, on the ground side, a load-distributor plate, which is not connected to the foundation, wherein the load-distributor plates together form the ballast of the tower.
US10781078B2 Elevator track cleaner
The invention is directed to an elevator track cleaner. The track cleaner is provided in a rectangular scrub brush configuration, providing a platform with a raised handle affixed to the top surface. The bottom surface provides a longitudinal band of stiff, flexible bristles along the centerline, and two longitudinal bands of small hooks on either side of the bristles for the purpose of securing a flexible white scrub pad. The pad is used to scrub the elevator track, with the bristles urging the pad into the groove where the track is located.
US10781076B2 Elevator buffer system
An elevator buffer system includes a buffer (44), a frame (30) spaced above the buffer, a platform (48) spaced above the frame, and a pre-compressed pad device (52) disposed between the frame and the platform and engaged to one of the frame and the platform. The system is constructed to move between a non-strike position, where the pre-compressed pad device is spaced from the other of the frame and the platform; a mid-strike position, where the pre-compressed pad device is in contact with the other of the frame and the platform; and a full-strike position, where the pre-compressed pad device is further compressed against the other of the frame and the platform.
US10781070B2 Device and method for forming three dimensional shape to elongated material
A device and method for forming a knot to elongated material is provided. The device includes a body, a central cavity inside the body, a material track along which the elongated material is guided in the device, the material track including opening extending along the material track and open to the central cavity. The device further includes one or more barrier elements for blocking at least part of the opening for preventing the elongated material from escaping from the material track also prevents collapsing/folding of the material to the central cavity via the opening.
US10781067B2 Slide cutter box
Container having a base portion defining a compartment and a lid portion moveable between an open position for access to the compartment and a closed position to cover the compartment. The base portion includes a bottom panel, a back panel extending from the bottom panel to a back panel upper edge, and back side tabs extending from the back panel and defining opposing sides of the base portion. The base portion further includes a front base panel extending upwardly from the bottom panel to a front angle panel, the front angle panel extending upwardly and inwardly from the front base panel to a free end. The lid portion is hingedly-coupled to the upper edge of the back panel. The container further includes a cutter disposed on the front angle panel. A blank and method for forming the container from a sheet of blank material is also provided.
US10781066B2 Sheet postprocessing device and image forming system therewith
A sheet postprocessing device includes a sheet conveying passage, a sheet tray, an inlet guide, a processing device, and a blowing device. Though the sheet conveying passage, a sheet on which an image has been formed is conveyed. The sheet tray is arranged downstream of the sheet conveying passage and has sheets stacked on it. The inlet guide is arranged at the downstream end of the sheet conveying passage and guides a sheet to the sheet tray. The processing device performs predetermined processing on a sheet stacked on the sheet tray. The blowing device blows air, from the upstream side in the sheet conveying direction, between the top face of the top-most sheet in the sheets stacked on the sheet tray and the bottom face of the subsequent sheet sent from the inlet guide into the sheet tray.
US10781062B2 Vehicle restraint system
A vehicle restraint system that includes a carriage and a hook that is moveable relative to the carriage. The hook is moveable between an engaged or extended position wherein the hook interferes with translation of vehicle relative to the vehicle restraint system and a disengaged or retracted position wherein the vehicle can be associated with or removed from interaction with the vehicle restraint system. The hook is secured to the carriage via an eccentric pivot assembly such that translation of the hook relative to the carriage includes an least partially lateral translation of the hook relative to the carriage thereby improving the repeatability associated with operation of the restraint system to securely engage and disengage respective vehicles from the restraint system without independent manipulation of the position of the vehicle relative to the restraint system.
US10781059B2 Bag conveyance method and bag conveyance apparatus
A bag in which a content is put and of which a mouth portion is not sealed, is disposed in a substantially horizontal attitude in a takeoff area. A height direction position of an expected hold part of the bag and a height direction position of a hold member are caused to correspond to each other. The hold member is caused to hold the expected hold part of the bag disposed in the takeoff area in a state where the height direction position of the expected hold part of the bag and the height direction position of the hold member correspond to each other. The hold member is moved to transfer the bag from the takeoff area to a delivery area after the hold member holds the expected hold part of the bag disposed in the takeoff area.
US10781049B2 Magnetic material handler
A material handler that uses chain driven magnetic plates to create a magnetic surface. The magnetic surface undulates and is able to lift ferrous material such as metal cans. The handler allows metal cans that are palletized to be removed quickly and easily.
US10781047B2 Air-supported belt conveyors and systems and methods of using same
Disclosed herein are air-supported belt conveyors and independent conveyor subsystems that are selectively and independently designed to meet requirements that can change along the length of a conveyor, as well as from conveyor to conveyor.
US10781046B2 Vacuum nose roll
Apparatus for transporting material in a manufacturing process are disclosed. A disclosed vacuum conveyer system may comprise a vacuum box extending between a first box end and a second box end, the vacuum box comprising a vacuum box vacuum chamber, a nose roll disposed adjacent to the first box end, the nose roll comprising a nose roll vacuum chamber, and a foraminous member disposed about both of the nose roll and the vacuum box. The vacuum system may further comprise a first airflow conduit connecting the vacuum box vacuum chamber to a vacuum source and a second airflow conduit connecting the nose roll vacuum chamber to the vacuum source.
US10781045B2 Box moving device
A box moving device is disclosed. The box moving device changes the position of a box having four side surfaces. The box moving device is equipped with a conveyor and a movement control unit. The movement control unit drives the conveyor to cause the box to move from a first position to a second position. The conveyor can alternately switch between a first state, in which it is contracted along a moving direction of the box, and a second state, in which it is extended along the moving direction of the box. The movement control unit causes the box to move from the first position to the second position by driving the conveyor that is in a holding mode in which it holds at least one of the side surfaces of the box and simultaneously switching the conveyor from the first state to the second state.
US10781044B2 Order fulfillment system and method with sortation at induct
An order fulfillment system and method includes a data base that is adapted to store data defining a plurality of customer orders. Each of the customer orders is a single item order having only one particular inventory item assigned to that order or a multiple item order having multiple particular inventory items assigned to that order. An inventory area stores inventory items that are available for fulfilling customer orders, and is responsive to said data base to retrieve particular inventory items from said inventory area that are assigned to customer orders in order to fulfill those orders. A sortation system combines particular inventory items together that make up an order. The sortation system has an automated induct subsystem and a sorter. The induct subsystem receives inventory items from the inventory area and forwards, in responsive to the data base, particular inventory items assigned to multiple-items orders to the sorter to be combined together to make up the multiple-item orders, but not particular inventory items assigned to single item orders. The sorter includes a pouch sorter having individual pouches and an overhead conveyor with tracts that route individual pouches to various destinations. The induct subsystem places a particular inventory item assigned to a multiple item order in an individual pouch and doesn't place a particular inventory items assigned to a single item order in a pouch. In this manner, handling of the particular inventory items for single items orders is separate from the pouch sorter thus reducing handling of inventory items and increasing system through-put.
US10781042B2 Ejection blade for a compaction chamber of a waste collection vehicle
An ejection blade for a compaction chamber with a hopper, the ejection blade including a blade body movable between a first position and a second position within the compaction chamber, and a lip attached to a lower portion of the blade body, the lip is movable to a raised position with respect to a floor of the compaction chamber when the blade body is moving to the first position and is in a lowered position with respect to the floor of the compaction chamber when the blade body is moving to the second position, wherein the first position is proximal to the hopper and the second position is distal to the hopper.
US10781040B1 Front load refuse container and lift pocket assembly
A front load refuse container made according to this invention has its four walls integrally formed out of a single piece of sheet metal. To form the walls, the single sheet is welded along a single vertical seam to form a circular-shaped ring. The circular-shaped ring is subjected to a swedging process that produces a rectangular-shaped ring with rounded corners.
US10781039B2 Extender for receptacle and method thereof
A method and apparatus including a garbage can, the garbage can having a lid and sized and dimensioned to be manipulated by a garbage truck, wherein the garbage can includes a substantially rigid body and a closed bottom, and an extender permanently coupled to the lid of the garbage can, the extender including a plurality of walls, wherein, when in a first position, the plurality of walls are collapsed into a flat position on the lid of the garbage can, and when in a second position, the plurality of walls are in an upright position defining an interior space for receiving waste materials, is provided.
US10781038B2 System for containing medical waste with a bag and machine for producing said bag
The invention relates to a system for containing medical waste with a bag and a machine for producing said bag. It relates to a reusable, hermetically sealed, metal container for medical waste, with a bag and locks or latches, which prevent the lid from being opened until the waste inside the same has been sterilized by the pressurized steam of an autoclave. It also relates to said plastic bag made up of two or more layers of different physical properties, configured into a single body. Said bag is housed inside the aforementioned hermetically sealed container. It also relates to a machine for producing these bags with a winder, folder and several sealers using heat resistance inserted into conveyer belts.
US10781034B2 Pack for smoking articles
A pack for smoking articles including: a container having front, rear, first side and second side panels and curved edges connecting the front, rear, first side and second side panels the container defining a chamber for storing smoking articles and an opening through which smoking articles are removable from the chamber; an inner frame projecting through the opening from within the chamber, the inner frame having a front portion and first and second side portions (230, 250) extending from first and second sides of the front portion to respective free ends (280, 290) of the inner frame, wherein the free ends (280, 290) of the inner frame are spaced apart from the first and second side panels (130, 170) of the container and abut the rear panel of the container; and a lid having front, rear, first side and second side panels and curved edges connecting the front, rear, first side and second side panels of the lid, the lid defining a cavity, where the rear panel of the lid is hinged to the rear panel of the container so that the lid is movable relative to the container between a closed position, at which the lid blocks the opening with the inner frame projecting into the cavity of the lid, and an open position, at which the lid does not block the opening.
US10781030B2 Content dispensing container apparatus
A content dispensing package apparatus is provided. The content dispensing package apparatus can be configured to elevate contents for immediate dispensing to the user, the user able to raise the contents from outside an outer container. For example, a container for dispensing edible contents can include a first container portion, a second container portion configured to move between a first position and a second position, and a tab coupled to the second container portion. The tab can be accessible from the outside of the container and used to move the second container.
US10781029B2 Apparatuses for depositing an extrudable substance onto a surface
An apparatus for depositing an extrudable substance comprises a bracket and a sleeve, comprising an inner tubular sleeve wall and an outer tubular sleeve wall. The sleeve is coupled to the bracket and is rotatable relative to the bracket. The apparatus also comprises a cartridge, comprising an inner tubular cartridge wall and an outer tubular cartridge wall, wherein the cartridge is configured to be positioned between the inner tubular sleeve wall and the outer tubular sleeve wall. The apparatus additionally comprises a valve, configured to be communicatively coupled with the cartridge, a nozzle, configured to be communicatively coupled with the valve, a linear actuator to control flow of the extrudable substance from the valve to the nozzle, an annular plunger, positioned between the inner tubular cartridge wall and the outer tubular cartridge wall, and a twist-lock pressure cap, configured to be hermetically coupled with the cartridge.
US10781028B2 Insulating device backpack
An insulating device can include an aperture having a waterproof closure which allows access to the chamber within the insulating device. The closure can help prevent any fluid leakage into and out of the insulating device if the insulating device is overturned or in any configuration other than upright. The closure may also prevent any fluid from permeating into the chamber if the insulating device is exposed to precipitation, other fluid, or submersed under water. The insulating device may include a back panel support structure and shoulder straps allowing the device to be worn as a backpack. This construction results in an insulating chamber that is substantially impervious to water and other liquids when the closure is sealed.
US10781023B2 Device for controlling gas, vapor, pressure within a package
A device for controlling package pressure and gas flow for a packaged good comprises a film having a first opening for exposure to the inside of a package and a second opening for exposure to the outside of a package. A channel extends between the first opening and the second opening. The dimensions of the channel are configured to control the rate of flow of CO2 (cc/min @ 1 PSI) from the inside of the package to the outside of the package and control the oxygen transmission rate (cc/day/Atm) from the outside of the package to the inside of the package so that a flow of CO2/OTR ratio is at an acceptable level for the packaged good.
US10781019B2 Child resistant pail
An improved lid and pail combination provides a child resistant connection for use with pails.
US10781012B2 Lid of a container
The invention relates to a lid (100) of a container, especially a beverage can, comprising a substantially flat lid surface (101) and a preferably folded edge area (102), as well as at least one pouring opening (103) provided on the lid surface (101), which can be closed in a gas- and/or liquid-tight manner by means of at least one closure element (120), with the closure element (120) being movable from a closed position into an open position by means of an actuating element (110), the actuating element (110) comprises a fixing element (111) and a sliding element (113), and the fixing element (111) is connected to at least one connecting element (115) via at least one predetermined breaking point before opening for the first time and the fixing element (111) has a handle (114) which, upon movement of the fixing element (111) from the closed position into the open position, acts on the at least one predetermined breaking point via at least one edge (114a).
US10781008B2 Rotary cup filler
A rotary cup filler has a cup holder plate that permits cup holders to be retained in place by inserting them into open-ended receptacles from the side of the cup holder plate rather than being inserted into openings in the bottom cup holder plate from beneath. In one configuration, the cup holder plate has a central hub and plurality of arms that extend arcuately from the central hub to form the receptacles therebetween. The arms may engage opposed sides of a circumferential groove in the associated cup holder.
US10781002B2 Method, device and system for filling pharmaceutical containers
In one general aspect, a method for filling multiple containers with a pharmaceutical product is disclosed, which comprises decontaminating sealed nested materials in a transfer chamber, removing from the sealed nested materials one or both of a container nest holding the multiple containers and a closure nest holding multiple closures, transferring from the transfer chamber to a controlled environment enclosure the removed nest, aseptically filling the containers with the pharmaceutical product, and closing the containers with the multiple closures. The nests are configured to allow multiple closures and containers to be simultaneously aligned concentrically, and closed simultaneously. Spring-loaded retaining structures on the closure nest allow it to releasably retain multiple closures above the corresponding multiple containers. In some embodiments the spring-loaded features are monolithically integrated with the closure nest. The product may be lyophilized in partially sealed containers while the sealing closures are releasably retained by the closure nest.
US10781001B2 Fill and finish systems and methods
A variety of fill options is provided for a cell processing system. Certain options relate to a filling system associated with the cell processing system, the filling system comprising one or more filling stations, each with at least one container that may receive product from a container associated with a cell processing system. Other options relate to a syringe assembly that receives a product from a container associated with a cell processing system.
US10781000B2 Apparatus and process for forming water soluble pouches
An apparatus including: a plurality of forming molds, each mold including: a leading edge; a trailing edge; a mold face; a plurality of first recesses in the mold face positioned across the mold face, each first recess in fluid communication with a first vacuum duct; a leading face extending from the leading edge in a direction away from the mold face; a trailing face extending from the trailing edge in a direction away from the mold face; wherein at least a portion of the leading face is recessed relative to the mold face proximal the leading edge or at least a portion of the trailing face is recessed relative to the mold face proximal the trailing edge; wherein the plurality of forming molds is arranged leading edge to trailing edge as a first mold belt.
US10780983B2 Sewn alternate inflate pneumatic de-icer
A de-icing assembly for a surface of an aircraft includes a carcass with a first layer and a second layer, a plurality of seams sewn into the carcass, and a bonded region. The plurality of seams join the first and second layers of the carcass together. Each of the plurality of seams comprises two or more stitchlines. The bonded region is disposed between the two or more stitchlines and seals a portion of the first layer of the carcass to a portion of the second layer of the carcass.
US10780982B2 Cooling systems having inline supplemental ram air heat exchangers
A cooling system for a vehicle can include a coolant loop having a coolant therein and configured to be in thermal communication with a heat load to receive heat from the heat load, a refrigeration system comprising an evaporator in thermal communication with the coolant loop to receive heat from the coolant loop, and a condenser configured to be in thermal communication with ram air to remove heat from the refrigeration system, an inline ram air heat exchanger disposed in a ram air stream of the condenser, and a ram air cooling branch in fluid communication with the coolant loop and configured to direct coolant to the ram air heat exchanger to cool the coolant.
US10780981B2 Aircraft seat rail mounting member
An aircraft assembly with first and second seat rails for interlocking with an aircraft seat, and a systems component mounting member interlocked with those seat rails. The mounting member has a first anchor member interlocked with the first seat rail and a second anchor member interlocked with the second seat rail. The assembly includes an aircraft systems component mounted on the mounting member. Existing seat rails or tracks of the aircraft can be used for attachment of support brackets for aircraft systems components. A novel way of using existing seat rails to provide anchorage points for systems brackets for systems components is disclosed.
US10780980B2 Electronic baggage stowage system and methods
An electronic baggage stowage system for an aircraft comprising a first detector to detect free space in a cabin stowage space, wherein the first detector is configured to output cabin stowage space data based on the detection, a processing unit communicating with the first detector, wherein the processing unit is configured to process the cabin stowage space data, receive and process baggage size data indicating the size of one or more baggage items, and output baggage stowage mapping data in response to the processing of the cabin stowage space data and the baggage size data. The baggage stowage mapping data indicates one or more target positions in the cabin stowage space at which the baggage items are to be placed. An indicator communicates with the processing unit to provide the indication of the one or more target positions to a flight attendant or passenger of the aircraft.
US10780979B2 Drone rotor cage
Disclosed is a drone rotor cage. The drone rotor cage may include a motor housing, a plurality of spars, and a plurality of ribs. The plurality of spars may extend from the motor housing. Each of the plurality of spars may have a spar height and a spar thickness. The spar height may be greater than the spar thickness. Each of the ribs may extend from a respective one of the plurality of spars. Each of the plurality of ribs may have a rib height and a rib thickness. The rib height may be greater than the rib thickness. The plurality of spars and the plurality of ribs may define a space sized to allow a rotor to spin freely when the rotor cage is attached to a drone.
US10780977B2 Aerodynamic control surface movement monitoring system
An actuator system for controlling a flight surface of an aircraft includes a first actuator having a first actuator input and a first linear translation element that moves based on rotational motion received at the first actuator input and a first sensor coupled to the first linear translation element that generates a first output based on a displacement of the first linear translation element. The system also includes a second actuator having a second actuator input and a second linear translation element that moves based on rotational motion received at the second actuator input and a second sensor coupled to the second linear translation element that generates a second output based on a displacement of the second linear translation element. The system also includes a control unit that receives the first and second outputs and determines if an error condition exists for the system based on first and second output.
US10780975B2 Clip-on propeller mount
A propulsion unit includes a motor rotor, a clip-in base mount, a clip-in rotor cap, propeller mounts, and propeller blades. The motor rotor spins about a central rotational axis. The clip-in base mount is disposed on the motor rotor. The clip-in rotor cap is shaped to mate with and detachably clip into the clip-in base mount. The propeller mounts are attached to the clip-in rotor cap. The propeller blades each have a proximal base and a distal tip. The proximal base of each propeller blade mounts to a corresponding one of the propeller mounts.
US10780973B2 Carbon nanotube heaters for aircraft heated floor panels
A floor panel includes a first structural layer, a film heater configured to emit far-infrared radiation, and a first open cell layer disposed between the film heater and the first structural layer such that far infrared radiation from the film heater is directed toward the first open cell layer.
US10780971B2 Methods of manufacturing a panel having a composite stringer for a vehicle
Methods of manufacturing a panel for a vehicle that includes forming a stringer from separate charges. The method can include positioning a forming sheet between the charges that are aligned in an overlapping arrangement. The charges can be held together and the forming sheet can be used to separate the ends of the charges to form flanges that extend outward from a blade. While still secured together, the formed stringer can be moved to a panel and positioned with the flanges contacting against the panel. Filler material can be positioned in an opening formed between the ends of the flanges.
US10780970B2 Folding heavy-lift unmanned vehicle frame
A heavy-lift UAV frame includes a central frame portion having a symmetrical shape and forming a pocket area for receiving an avionics package. Top and bottom plates are secured to the central frame portion and include four corner members that extend diagonally outward therefrom. A plurality of boom arms are pivotally connected to the corner members and transition between an extended position for flight and a retracted position for storage and transport. Each boom arm includes a complementary dimension to one side of the central frame portion and is arranged parallel thereto when in the retracted position.
US10780968B2 Systems and methods for wave sensing and ship motion forecasting with operational period indicators
Systems and methods and described herein that can enable accurate forecasting of ship motions and the useful displaying of such forecasts to users. In general, the ship motion forecasting systems and methods provide users with graphical indication of ship motion forecasts in the form of operational period indicators. These operational period indicators are generated such that the ship motion forecasts under at least one motion threshold for a time period exceeding a time threshold are indicated in a first way, while ship motion forecasts not under the at least one motion threshold for the time period exceeding the time threshold are indicated in a second way, different from the first way. This can facilitate the quick determination of operational status by a user and thus allow a user to quickly ascertain when conditions are likely to be such that certain ship operations can be safely performed.
US10780964B1 Method and apparatus for propulsion of kayaks and other watercraft
A propulsion assembly utilizes at least one fluid propulsion chamber operationally attached or mounted to a vessel. Each fluid propulsion chamber generally comprises an outer housing and an inner sleeve; the outer housing is slidably disposed relative to the inner sleeve. Each inner sleeve further includes at least one water intake vent or aperture, and at least one outlet nozzle or jet. Pedal assemblies are moveably mounted within elongated slots or apertures extending through the vessel. A linkage assembly operationally connects the pedals to the at least one fluid propulsion chamber. Force imparted on said pedals (such as by the legs/feet of a user) is transferred to the fluid propulsion chambers by said linkage assembly to generate positive thrust to propel the vessel.
US10780963B2 Thruster for propelling a watercraft
A thruster for propelling a watercraft comprises at least one propeller on a rotatable propeller shaft and a motor for driving the propeller shaft through a drive arrangement, particularly a drive arrangement comprising a rotatable drive shaft and a coupling arrangement arranged between the drive shaft and an output shaft of the motor for coupling the drive shaft to the output shaft of the motor. The motor is a permanent magnet motor, the stator body of the motor being provided with a recess surrounding at least a part of the output shaft of the motor, and the coupling arrangement being at least partially located inside the recess so that a configuration having minimal constructional height is obtained.
US10780961B2 Method of establishing communication for sub-ice submarine missions between a sub-ice vessel and a terrestrial facility using a laser-powered ice-penetrating communications delivery vehicle
A laser-powered ice-penetrating communications payload delivery vehicle for sub-ice submarine missions enables under-ice operations to exchange information with terrestrial facilities or satellite networks with communications methods otherwise blocked by an ice cap. The vehicle comprises an electronics bay, a payload bay, optics bay, and a melt optic with laser. The system and method of establishing communication where the vehicle, tethered to a sub-ice vessel, is released. The vehicle ascends to the bottom of an ice sheet and uses a laser to melt the ice, forming a borehole through which the vehicle continues to ascend. When buoyancy no longer advances the vehicle beyond sea level, the vehicle continues to melt a conical opening through the ice until unobstructed atmosphere is reached and bi-directional communication is established. Where the melting capacity cannot reach ice to continue melting, the vehicle mechanically advances itself toward the surface to establish high bandwidth, bi-directional communication.
US10780959B1 Swimming aid
A swimming aid with a lower back float and an abdominal float, where the floats provide sufficient buoyancy to keep the user's head, neck and shoulders above water when the user is in a vertical position and in a mostly horizontal position. The floats overlap axially so that the user is biased to a vertical position, but can easily rotate between a mostly horizontal position for learning how to swim, and a vertical position, with head, neck and shoulders above the water in both positions, for ease and comfort of breathing, without falling over backwards or sideways.
US10780958B2 Open/non-closed, buoyant hull collar assemblies
An embodiment includes an open/non-closed hull collar assembly that is shaped to increase encapsulated volume of a hull. The hull collar assembly may include a hull collar structure and a foam module. The hull collar structure may include a gunwale, an outboard boundary, and an inboard boundary. The outboard boundary extends in an outward lateral direction from a lower hull portion and extends in a longitudinal direction from the lower hull portion such that at least a portion of the hull collar structure is at least partially included in a freeboard portion of a boat hull. The inboard boundary extends from the gunwale a portion of a distance to a deck such that the hull collar structure is at least partially open or non-closed to an inner hull volume. The foam module is comprised of a non-expansive, closed cell foam. The foam module is shaped for disposition within the hull collar structure.
US10780957B2 Board-type watercraft
A board-type watercraft is adapted for selective disassembly into a plurality of separate sections for ease of transport and storage. Preferably, a selection of differently configured nose and tail sections can be releasably connected to a universal middle section to create a wide variety of distinctive board styles. With the watercraft in its assembled state, adjacent sections are releasably secured together using compressive-type fastening elements, such as spring-biased latch mechanisms. Pairs of fastening elements are preferably arranged on the top and bottom surfaces of the board in substantial vertical alignment to limit torque between sections and thereby ensure adequate stiffness through each joint. In its disassembled state, the sections can be stacked into a highly compact configuration suitable for packaging within a container that is compliant with maximum size standards for conventional ground courier services.
US10780954B2 Systems and methods for in situ assessment of mooring lines
A system can include at least one measuring device that captures and collects multiple two-dimensional images of a mooring line disposed in water. The system can also include a mooring line assessment system that includes a controller communicably coupled to the at least one measuring device. The controller can receive the two-dimensional images from the at least one measuring device. The controller can also generate a three-dimensional reconstruction of the mooring line based on the two-dimensional images. The controller can further present the three-dimensional reconstruction to a user. The two-dimensional images can be captured and the recommendation can be made while the mooring line is in situ.
US10780952B1 Bladder anchor system
An anchor system with a bridle substrate and harness configured to attach to an anchor line. An outer bladder surrounds an inner bladder for coupling on top of the bridle substrate. Water enters the anchor system through a water inlet that feeds directly to the inner bladder and fills that first. Water then overflows from the inner bladder to the outer bladder to fill that second. The inner bladder provides stability and is positioned with a majority of its volume closer to an uphill end of the anchor bladder while the outer bladder is positioned with a majority of its volume closer to a downhill end of the anchor bladder. Reinforcement connectors for each bladder resist deformation of the bladders to resist movement of the anchor bladder while filling.
US10780951B2 Marine thru-hull fitting and drainage device
A marine thru-hull fitting drainage device includes: a channel body having a substantially U-shaped cross-sectional area along a length of the body such that the body forms a channel for directing fluid within the body, the body extending from a first end proximate to the hull of the vessel when the drainage device is installed and a second end that is distal from the hull of the vessel, wherein the second end extends beyond an edge of the thru-hull fitting; and a ring having an inner diameter that is at least as wide as a diameter of the bore in the hull of the vessel, the resiliently flexible channel body attached to the ring at the first end of the channel body. The drainage device is secured to the hull of the vessel by securing the ring between the thru-hull and the hull of the vessel.
US10780950B2 Snowmobile ski dampener
An improved snowmobile ski dampener for dampening articulation between a steering spindle and a snowmobile ski. The ski dampener may be constructed of an elastomeric material and include one or more progressive surfaces that progressively come in contact with a base surface of the steering spindle as progressively increased compressive loads are applied between the steering spindle and snowmobile ski. As the progressive surfaces come in contact with the base surface, the shape factor of the ski dampener may change (e.g., increase), reducing compressive strain for a given compressive stress. Various design and material characteristics including width, shape of the progressive surface, and durometer and bulk modulus of the elastomeric material may be selected to provide various performance characteristics such as dampening effect, impact absorption, approach angle, initial flex force, and service life.
US10780944B2 Transmission system and its use
The present application describes a transmission system, including a certain tooth profile of toothed wheel and its use. This transmission system enables an improved guidance of the chain by using a non-normative tooth profile, to avoid that when the vehicle is exposed to extreme situations disengagements of the chain may occur. This transmission system applies to vehicles, preferably bicycles.
US10780943B2 Human-hybrid powertrain for a vehicle or moving equipment using magnetorheological fluid clutch apparatus
A system for assisting a user in moving a device relative to a structure comprises a magnetorheological (MR) fluid actuator unit including at least one torque source and at least one MR fluid clutch apparatus having an input coupled to the at least one torque source to receive torque from the at least one torque source, the MR fluid clutch apparatus controllable to transmit a variable amount of assistance force via an output thereof. An interface is configured for coupling the output of the at least one MR fluid clutch apparatus to the device or surrounding structure. At least one sensor provides information about a movement of the device. A processor unit for controlling the at least one MR fluid clutch apparatus in exerting the variable amount of assistance force as a function of said information, wherein the system is configured for one of the MR fluid actuator unit and the interface to be coupled to the structure, and for the other of the MR fluid actuator unit and the interface to be coupled to the device for the assistance force from the MR fluid actuator unit to assist in moving the device.
US10780942B1 Pedal structure
A pedal structure includes a pedal body, a first bearing, a stopping element, a central axle, and a fixing element. The pedal body has a receiving space, and a fixing hole is formed at an end of the receiving space. A first stepped face is formed around the fixing hole. The first bearing is received in the receiving space and abuts against the first stepped face. The stopping element is received in the receiving space and abuts against the first bearing and is engaged with the inner wall of the receiving space. The central axle is inserted through the stopping element and the first bearing. The fixing element is inserted through the fixing hole to engage with the central axle to pull the central axle toward the first bearing.
US10780936B2 Straddle-type vehicle
A straddle-type vehicle includes a drive unit used for driving a rear wheel of the straddle-type vehicle, wherein a discharge port that discharges oil in the drive unit is installed on a lower section of the drive unit, and a guide that guides oil to an outside in a vehicle width direction is installed in a vicinity of a lower section of the discharge port.
US10780932B2 Bicycle telescopic apparatus
A bicycle telescopic apparatus includes a first tube, a second tube, an actuating member, and a hydraulic positioning structure. The first tube defines an axial direction. The second tube is telescopically received in the first tube in the axial direction. The actuating member is movable relative to the first tube in the axial direction of the first tube. The actuating member is configured to move the second tube relative to the first tube in the axial direction. The hydraulic positioning structure is configured to position the first tube and the second tube relative to each other in the axial direction.
US10780926B2 Reinforcing unit and side reinforcing structure of vehicle including the same
A reinforcing unit is configured to be inserted into a side sill of a vehicle body. The reinforcing unit includes a center core formed so as to extend in a longitudinal direction of the vehicle body, and a pair of cover cores formed so as to extend in the longitudinal direction of the vehicle body and arranged so as to cover an upper portion and a lower portion of the center core.
US10780925B2 Vehicle body structure
A vehicle body structure includes a roof rail structure, a pillar structure, a tube-like reinforcement member and an attachment assembly. The tube-like reinforcement member is shaped to include a first portion, a curved portion and a second portion such that the first portion is fixed within and extends along a portion of the roof rail structure and the second portion extends downward within and extends along an upper portion of the pillar structure. The attachment assembly includes a bracket and a positioning member disposed within the pillar structure. The bracket is fixedly attached to the pillar structure. The second portion of the tube-like reinforcement member extends through an oversized opening in the bracket. The tube-like reinforcement member is fixedly attached to the positioning member and the positioning member being fixedly attached to the bracket.
US10780923B2 Vehicle platform
A vehicle includes a vehicle frame elongated along a longitudinal axis. The vehicle frame includes a first rail and a second rail spaced from each other and each elongated along the longitudinal axis. The vehicle frame includes a longitudinal beam between the first and second rails and elongated along the longitudinal axis. The vehicle includes a vehicle body. The vehicle body includes a cross-beam directly connected to the longitudinal beam and to the first and second rails.
US10780920B2 Deviation avoidance apparatus
A deviation avoidance apparatus of an embodiment includes a boundary detection section that detects boundaries of a travelling path on which an own vehicle travels; a deviation prediction section that predicts that the own vehicle will deviate from the travelling path based on a travelling condition of the own vehicle that travels in the travelling path defined by the boundaries detected by the boundary detection section; a deviation avoidance section that commands, when the deviation prediction section predicts that the own vehicle will deviate from the travelling path, a steering control unit to have a steering actuator drive a steering mechanism that changes a traveling direction of the own vehicle such that the own vehicle avoids deviating from the travelling path; and a notification section that notifies vehicle passengers, via a notification unit, when the steering actuator applies driving force to the steering mechanism such that the own vehicle avoids deviating from the travelling path, that deviation avoidance of the own vehicle is ongoing.
US10780914B2 Steering instability detection
A method of detecting steering wheel angle instability in an auto-guided vehicle includes measuring a steering wheel angle at a plurality of time instances within a pre-determined time window to obtain an array of values of the steering wheel angle, performing a frequency analysis of the array of values of the steering wheel angle to obtain a frequency spectrum of the steering wheel angle, comparing the frequency spectrum of the steering wheel angle to a pre-defined threshold frequency spectrum to determine whether a magnitude of the frequency spectrum of the steering wheel angle at any frequency exceeds a magnitude of the threshold frequency spectrum, and upon determining that a magnitude of the frequency spectrum of the steering wheel angle at one or more frequencies exceeds a magnitude of the pre-defined threshold frequency spectrum, determining that a steering wheel angle instability is present.
US10780913B2 Method of controlling a motor of an electric power assisted steering system
A method of controlling a motor of an electric power assisted steering system, the motor having a plurality of phases, the method comprising taking as an input an input signal indicative of a desired assistance torque and determining from the desired assistance torque a voltage to be applied to each of the phases of the motor, in which the step of determining the voltage to be applied to each of the phases comprises limiting the voltage determined to be applied to each of the phases of the motor dependent upon the voltage provided by a power supply to the motor.
US10780909B2 User interface for steering wheel
An interactive user interface for a steering wheel is provided. A user interface is provided on one or more portions of the steering wheel. The user interface recognizes gesture movements made by a user thereon. The user interface allows navigation of a set of controls associated with a menu provided through the user interface based on the recognized gesture movements.
US10780908B2 Steering grip light bar systems
Various implementations include a light bar system for a steering wheel of a vehicle that includes a high intensity light source, a light diffusing layer, and an outer lens. For example, in certain implementations, the light diffusing layer is disposed between a plurality of high intensity light emitting diodes (LEDs) and an outer lens, and the light diffusing layer causes the light from the LEDs to appear as a continuous stream of light across a length of the lens and provides sufficiently bright lighting to warn or communicate with the driver in various ambient lighting conditions. In certain implementations, the outer lens is colored to blend in with the rest of the steering wheel when the LEDs are not activated.
US10780906B2 Dolly for transporting products
A dolly for transporting products thereon, the dolly comprising a top with a product support surface and an opposing underside, a plurality of casters provided on the underside, two of the casters being swivel casters configured to rotate relative to the product support surface; biasing means configured to bias a wheel of each swivel caster towards a first equilibrium position. A plurality of reinforcing ribs provided on the underside; wherein at least one of the reinforcing ribs is a curved reinforcing rib, and; the at least one curved reinforcing rib extends from a first caster mounting area to a second caster mounting area. Further including, a dolly carrier pallet comprising a pallet provided with a dolly receiving layer, wherein the dolly receiving layer is provided with generally rectangular wheel receiving recesses for receiving swivel casters and is provided with generally rectangular wheel receiving recesses for receiving fixed casters.
US10780903B2 Detection of dynamic train-to-rail shunting performance
Systems and methods for detecting the dynamic train-to-rail shunting performance of a train as it is moving along the rails of a railroad track. The systems and methods use portable equipment temporarily installed at a site where it is desired to test the shunting of one or more trains or the electrical equipment installed at the track. The systems and method use sensor plates and a high speed recording system to simultaneously capture measured train-to-rail shunting characteristics and the positioning of a train's axles and any rail conditions impacting the measurements. The captured information can be used to fine tune the train, the electrical equipment installed at the track and/or to design new devices.
US10780902B2 Rail vehicle drive with a brake device
A drive of a rail vehicle includes two drive wheels and a wheel set shaft which connects the drive wheels for rotation about an axis. A dynamoelectric machine includes a shaft extending axially parallel to the wheel set shaft and mounted for rotation about a further axis. A transmission connects the shaft of the dynamoelectric machine and the wheel set shaft by a non-positive fit. Placed between the dynamoelectric machine and the transmission is a coupling which is configured for direct attachment of a brake disk of a braking apparatus which is arranged between the transmission and the dynamoelectric machine.
US10780889B2 Apparatus for detecting road surface state in motor-driven power steering and control method thereof
Disclosed herein are an apparatus for detecting a road surface state in motor-driven power steering (MDPS) and a method for controlling the apparatus. The apparatus may include a column torque sensor to detect column torque applied to a steering column and to output a column torque signal; a steering angle sensor to detect a steering angular velocity of a steering wheel; a vehicle speed sensor to detect a driving speed of a vehicle; and a road surface determiner to determine a road surface state based on a boost gain, which is calculated based on the driving speed and the column torque, and on a phase offset between the column torque and the steering angular velocity and to output a road surface determination signal.
US10780887B2 Utility vehicle and method for operating a utility vehicle having a four-wheel drive and a differential lock
A utility vehicle and a method of operating a utility vehicle having a rear axle driven by a drive engine, a rear axle differential on the rear axle, and a front axle that is configured to be switched on to perform four-wheel drive are provided. The method includes activating a differential lock for locking the rear axle differential on the basis of at least one of a rear axle slippage variable, which characterizes a drive slippage occurring at the rear axle, an engine power of the drive engine, a status of at least one brake device associated with the rear axle, and a status regarding the four-wheel drive.
US10780881B2 Device for controlling vehicle at intersection
The present disclosure relates to a device for controlling a vehicle at an intersection. The device variably sets a region of interest of a vehicle sensor in accordance with a relationship between the progress paths of a subject vehicle and a target vehicle at an intersection, or controls the subject vehicle according to a collision avoidance control method in comparison with a predetermined scenario of a collision possibility of the subject vehicle and the target vehicle at the intersection according to a scenario, thereby preventing a collision at the intersection.
US10780879B2 Parking controller, parking control system, and parking control method
A parking controller according to one aspect of an embodiment includes a specific-parking-frame acquiring unit, a target-parking-frame setting unit, and a vacant-parking-frame detecting unit. The specific-parking-frame acquiring unit acquires information indicating a specific parking frame. The specific parking frame is a parking frame that is specified by an external device among from a plurality of parking frames in a parking lot. The target-parking-frame setting unit sets the specific parking frame as a target parking frame. The target parking frame is a parking frame to be a target. The vacant-parking-frame detecting unit detects a vacant parking frame while an own vehicle is travelling to the target parking frame. The vacant parking frame is a parking frame in a vacant state. The target-parking-frame setting unit changes, when the vacant-parking-frame detecting unit detects the vacant parking frame, the set target parking frame into the vacant parking frame.
US10780871B2 Apparatus and method for controlling pneumatic fluid to a trailer
A trailer control valve comprises a valve electronic control port adapted to receive an electronic control signal; a valve pneumatic supply port unrestrictedly fluidly communicating with a first supply of a pneumatic fluid; a valve pneumatic control port normally proportionally fluidly communicating with a second supply of the pneumatic fluid based on a pressure representing a driver brake demand, the first supply of the pneumatic fluid being in an independent pneumatic circuit from the second supply of the pneumatic fluid; and a valve delivery port selectively fluidly communicating with at least one of the valve pneumatic supply port and the valve pneumatic control port based on the electronic control signal, the pressure representing the driver brake demand and a pressure of the first supply of the pneumatic fluid. A first pneumatic check valve includes a first check valve supply port fluidly communicating with the first supply of the pneumatic fluid; and a first check valve delivery port fluidly communicating with the relay valve pneumatic supply port. The first pneumatic check valve controls the fluid communication of the first supply of the pneumatic fluid with the relay valve pneumatic supply port based on the pressure of the first supply of the pneumatic fluid at the valve pneumatic supply port.
US10780870B2 Railway vehicle comprising an emergency braking device
A railway vehicle, including an emergency braking device including at least one brake module, wherein each module includes a contact element intended to be in contact with the ground at the moment of braking, and movable between a retracted position and a deployed position in which the contact element is in contact with the ground and is able to slow down the moving railway vehicle by applying a pressure force to the ground, and at least one control unit that is capable of communicating commands to the brake module, wherein the control unit is able to communicate to the brake module the command to deploy the contact element to its deployed position when at least a portion of the vehicle leaves the track on which the vehicle is traveling.
US10780868B2 Hydraulic block for a braking system of a motor vehicle, and braking system for a motor vehicle
A motor vehicle braking system cuboidal hydraulic block includes at least one wheel connector to which at least one wheel brake cylinder is connectable, a master brake cylinder receiving borehole connected to the at least one wheel connector such that a master brake cylinder is at least partially providable in the master brake cylinder receiving borehole, and a plunger receiving borehole that extends from an engine side of the hydraulic block in the direction of an opposite side of the hydraulic block and that is connected to the at least one wheel connector such that a plunger of a motorized plunger device is providable therein.
US10780864B2 Disc brake
A disc brake includes a caliper; a pad pressed against a disc by a movable portion of the caliper and including a mounting ear portion provided to be protruded in a longitudinal direction of the pad; a pad spring including a guide plate configured to guide the mounting ear portion, and a first biasing member configured to press the mounting ear portion of the pad toward outside of the disc; and a second biasing member provided at the pad to bias the pad in a direction away from the disc. The guide plate of the pad spring has a surface that abuts on the mounting ear portion of the pad pressed by the first biasing member. The pad spring includes a folded region protruded in an axial direction of the disc from the surface abutting on the mounting ear portion of the pad, and folded in a direction toward the outside of the disc and away from the mounting ear portion. The folded region includes an abutting portion which the second biasing member provided at the pad abuts on.
US10780863B2 Cap, connecting device for mounting a windscreen wiper on a corresponding windscreen wiper arm and windscreen wiping system
The invention relates to a cap (17) which is configured to be assembled with a terminal segment (9) of a windscreen wiper arm (5) which is configured to be connected to a windscreen wiper (3), said terminal segment (19having a longitudinal end (11) bearing a transverse pin (13) which is configured to define a pivot axis of the windscreen wiper (3), the cap (17) comprising: an upper part (171) which is configured to cover the terminal segment (9) of the windscreen wiper arm (5) in the assembled state of the cap (17) on said terminal segment (9), a lower part (173), and at least one fixing means (23) which is configured to cooperate with the transverse pin (13). According to the invention, the lower part (173) of the cap (17) comprises at least one support means (19) which is produced integrally with the cap (17) and which is configured to cooperate with the terminal segment (9) of the windscreen wiper arm (5) for the assembly of the cap (17) with the terminal segment (9).
US10780859B2 Passenger seat airbag and method of folding the same
A passenger seat airbag includes a passenger side wall for catching a passenger, and a circumferential wall that extends forward from the passenger side wall in a converging fashion. The circumferential wall includes an upper wall, a lower wall, a left wall and a right wall, and can be mounted on a housing by the front end. An inlet port for introducing inflation gas is disposed at a front end region of the lower side wall, at a position displaced to the right from the center in a left and right direction of the passenger side wall. In the front end region of the circumferential wall, with respect to a substantial circumferential length which permits free expansion, a left circumferential wall region disposed on the left of the inlet port and a right circumferential wall region disposed on the right of the inlet port have equal substantial circumferential lengths.
US10780857B1 Vehicle occupant support
A system of air cushions adapted to ensconce the head of an occupant in a child seat during side impact, extendable to a system of air cushions with sacrificial chamber to inflate the aircushions.
US10780851B2 Power source device and vehicle equipped with power source device
A power source device of present disclosure includes: a first power storage element; a second power storage element that is connected in parallel to the first power storage element and that has a lower internal resistance than an internal resistance of the first power storage element and a lower storage capacity than a storage capacity of the first power storage element; an opening and closing part that is connected between the first power storage element and the second power storage element and that switches between a disconnection state and a connection state; a charge circuit that is connected to an input route of the first power storage element and that performs a step-down operation; a discharge circuit that is connected to an output route of the second power storage element and that performs a step-up operation; and a controller that controls operations of the opening and closing part, the charge circuit, and the discharge circuit.
US10780848B2 Vehicle floor structure
A vehicle floor structure includes a first floor member arranged on a floor of a vehicle; a second floor member arranged in a position that is horizontally offset with respect to the first floor member and is adjacent to the first floor member; a wire harness including a portion arranged below the first floor member and the second floor member, extending from a first floor member side to a second floor member side, and having an end situated on the first floor member side and coupled to a connector; and a restrictor configured to restrict a crossover portion of the wire harness to be below the connector. The crossover portion is a portion of the wire harness situated below an interface between the first floor member and the second floor member.
US10780845B2 Retention clip for vehicle molding
A clip is disclosed for securing a molding to a flange of a vehicle. The clip has a first side wall and a second side wall each comprising an interior surface and an opposing exterior surface. The interior surfaces face one another and the exterior surfaces are shaped to engage the molding. Each of the side walls terminate at a distal edge providing a passage for the flange. A base connects the side walls at an end that is opposite the distal edges. A tab extends from the base and is disposed between the side walls. The tab and the interior surface of the second side wall define a pocket sized to fit the flange of the vehicle. The interior surface of the second side wall comprises a bump that extends towards and faces the tab. The tab and the bump are configured to engage the flange.
US10780842B1 Sheet mounting system for vehicles
A mounting system for a sheet on a vehicle includes two elongate rub rails with undercut channels to receive the sheet and tensioning components. The upper rub rail is engaged with one of opposed edges of the sheet. An elongate engagement is engaged with the other opposed edge of the sheet and includes one frame rail and an engagement surface both facing the upper rub rail. An elongate retainer includes a bead engaged with the lower rub rail, another frame rail and parallel retainer surfaces, the second frame rail and the parallel retainer surfaces facing away from the upper rub rail. The engagement surface is movable laterally of the parallel retainer surfaces to be positioned in interlocking engagement with any one of the parallel retainer surfaces to tension the sheet.
US10780838B2 Hidden easy bike rack
A bicycle rack built into a vehicle's trunk is provided. In some embodiments, the present invention may comprise a bicycle rack that may slide along one or more tracks built into a vehicle's trunk, wherein the bicycle rack may extend from or retract into the vehicle's trunk. In some embodiments, the movement of the bicycle rack along the tracks may be automated according to one or more built-in features of the vehicle.
US10780829B2 Vehicle side mirrors
A vehicle side mirror (22) housing (12) base (17) and mirror (23) to view behind you.A vehicle side mirror (22) is concealed and revealed through an opening in the vehicle body (11) automatically when started, turned off, in park, in autonomous mode or manually with a switch, key fob or voice command.When concealed in the container (16) the vehicle allows for more room to pass and less damage to the un-exposed vehicle side mirror (22), when driving or in autonomous mode the vehicle side mirror (22) is concealed thus the vehicle can have an increase in fuel economy do to the decrease of the drag coefficient.
US10780828B2 Sensor mount structure
A sensor mount structure, including: a sensor device that detects information regarding at least a region ahead of a vehicle; a display device that displays images of at least a region behind the vehicle; a support member that covers a part of the sensor device from below and that is attached to a base member provided at an inner surface of a front windshield glass; an arm member that has an upper end portion attached to the support member and a lower end portion attached to a length direction center portion of the display device; and a cover member, a minimum distance between the cover member and an upper peripheral edge at a length direction end portion of the display device being longer than a minimum distance between the cover member and an upper peripheral edge at the length direction center portion of the display device.
US10780827B2 Method for stitching images captured by multiple vehicular cameras
A method for stitching images captured by multiple vehicular cameras includes disposing a plurality of cameras at the vehicle so as to have respective fields of view exterior the vehicle. Image data captured by first and second cameras of the plurality of cameras is processed to detect an object present in an overlapping portion of the fields of view of the first and second cameras. Image data captured by the first and second cameras is stitched, via processing provided captured image data, to form stitched images. Stitching of captured image data is adjusted responsive to determination of a difference between a characteristic of a feature of a detected object as captured by the first camera and the characteristic of the feature of the detected object as captured by the second camera in order to mitigate misalignment of stitched images.
US10780819B2 Vehicle winglet with sequential blinker
A vehicle winglet (e.g., sideview mirror, camera or radar assembly, etc.) is provided with sequential illumination of light-emitting diodes (LEDs). A light guide is connected to and covers the LEDs. The light guide is made of a translucent material and is configured to guide light illuminated by the LEDs and transfer the light out of the light guide. The light guide includes a plurality of light guide towers extending therefrom. Each light guide tower is aligned with a respective one of the LEDs. In some embodiments, a plurality of collimators are provided, with each collimator aligned with a respective one of the LEDs and with a respective one of the light guide towers to redirect the light illuminated from the respective LED into the respective light guide tower.
US10780815B2 Pickup truck loading device
A pickup truck loading device. The pickup truck loading device includes an elongated rod having a first end, a second end, and a central portion. A winch mount is disposed at the central portion of the elongated rod. A first end bracket and a second end bracket each include a channel and are each configured to mount to an upper rim of opposing sides of a truck bed. The first end of the elongated rod is slidably engaged within the channel of the first end bracket and the second end of the elongated rod is slidably engaged within the channel of the second end bracket.
US10780814B2 Method for delivery and/or collection of at least one mailing
Described and shown is a method for delivery and/or collection of at least one mailing. In order to reduce the associated cost and effort a vehicle (1) is drives to at least one receptacle (3) through public traffic at least in part and the at least one mailing to be delivered is taken from the vehicle (1) and placed into the receptacle (3) by a transfer device attached to the vehicle (1) and/or the at least one mailing to be collected is brought from the receptacle (3) to the vehicle (1) by the transfer device attached to the vehicle (1).
US10780813B2 Vehicle assembly having a sloped gate
The current disclosure relates to a tank trailer for transporting meat packaging by-products. The tank trailer has a cylindrical body having a sloped rear end. An opening is formed in the sloped rear end, and a gate selectively blocks the opening. A locking mechanism is provided to securely lock the gate to the cylindrical body, thereby sealing the cylindrical body. The sloped rear end forms a chute through which meat by-products can be poured. The chute extends for a distance rearwardly of the trailer's rear wheel assembly.
US10780812B2 Item holder having a self-adjusting air bladder system
An item holder includes a receiving well with an upper opening. First and second air bladders are disposed in the receiving well. Upper portions of outer casings of the air bladders are substantially flush with the upper opening of the receiving well when the air bladders are in an inflated condition. Also, the abutment portions abut one another along an abutment seam when the air bladders are in an inflated condition. A sensor may be sued to detect the receiving of an item in the receiving well. Valves assemblies are opened as the sensors detect an item being received in the receiving well. The item compresses a filler material disposed within the air bladders as the item is received in the receiving well. When the item is removed from the receiving well, the filler material expands to inflate the air bladders to the at-rest position.
US10780810B2 Actuator and method of actuating a latch
An actuator comprises a housing, a motor, a drive mechanism and a clutch coupled to the drive mechanism. The motor is mounted displaceably relative to the housing. A displacement of the motor relative to the housing is operative to actuate the clutch.
US10780806B2 Method for assembling an upholstery for a seat or for stuffed furniture and related upholstery
A method for assembling an upholstery for a seat or for stuffed furniture including the steps of: providing a first upholstery element and a second upholstery element to be sewn together, wherein the first upholstery element and the second element have a visible upper surface and a non-visible lower surface; placing a first edge of the first element alongside a first edge of the second element until they are in abutting contact, that is head against head, in a coplanar way; sewing the first edge of the first element to the first edge of the second element with a stitch chosen from classes 300, 400 or 600.
US10780805B2 Vehicle seat
An objective is to provide a vehicle seat that ensures a reduced effect on an appearance even when a sewn portion made by sewing the trim cover is bonded in a groove. A vehicle seat formed by bonding a trim cover to a foam pad is configured such that the trim cover includes a sewn portion made by sewing a plurality of skin materials, the foam pad has a groove, the vehicle seat is formed by the sewn portion of the trim cover and the sewn portion is bonded in the groove of the foam pad, and the groove includes a guiding portion that guides a seam allowance of the sewn portion to the groove, and a restricting portion that restricts the seam allowance of the sewn portion to support the seam allowance of the sewn portion in a state where the seam allowance of the sewn portion does not open.
US10780801B2 Vehicle seat
The present invention relates to a vehicle sheet with a seat back which is provided with a urethane pad covered with a trim cover, and a pressing unit on the reverse side of the urethane pad covered with the trim cover, the pressing unit being formed with a shaft extending laterally and a pair of pressure portions arranged in the vertical direction with respect to the shaft to support both the upper and lower sides of the urethane pad by detecting the intermediate position of turning movement of the pressing unit by means of a turning movement detection unit and stopping the turning movement of the pressing unit, or is configured to press forward the upper side of the urethane pad using the upper pressure portion or the lower side of the urethane pad using the lower pressure portion by turning the laterally-extending shaft of the pressing unit.
US10780795B2 Battery heating system and control method thereof
The disclosure provides a battery heating system and a control method thereof. The system includes a first switch, a second switch, a switch component, a motor, and a main controller. The first switch, the second switch, the switch component and the main controller are integrated in a same housing. The main controller is to determine, based on a state parameter of the battery pack, that the battery pack needs to be heated, and to send a battery heating request to a vehicle controller, so as to enable the vehicle controller to send a battery heating instruction to the main controller according to the battery heating request in a case where a vehicle is in a static state and the motor is not operating; and to control, based on the battery heating instruction, the first switch, the second switch and the switch component so as to heat the battery pack.
US10780789B2 Charging apparatus
A charging apparatus for charging at least one electric energy storage, in particular of motor vehicles, comprising a plurality of charging units, each charging unit having an AC/DC converter, a DC interlink circuit, a high-voltage energy storage and a DC/DC converter, wherein the charging units can be connected up on the output side as needed.
US10780783B2 Onboard vehicle communication system
An onboard vehicle communication system includes a first ECU configured to manage charge information of a vehicle, a gateway connected to the first ECU, a second ECU connected to the gateway, an onboard vehicle communication device configured to communicate with the outside of the vehicle, and a local bus that connects the first ECU and the onboard vehicle communication device. The first ECU is configured to transmit charge information of the vehicle to the onboard vehicle communication device via the local bus when an external charge device is charging a vehicle.
US10780782B2 Vehicle information display system
A vehicle information display system includes: a master-side instrument including a first power transmission coil, a first signal transmission coil, and a first case; and a meter instrument including a display unit, a second power transmission coil, a second signal transmission coil, and a second case. The master-side instrument and the meter instrument have a positional relation such that in a state in which a fitting recessed part of the first case and the second case are fitted to each other, the first power transmission coil is opposed to the second power transmission coil, and the first signal transmission coil is opposed to the second signal transmission coil.
US10780781B2 Display device for vehicle
A display device (100) for a vehicle includes: a plurality of display units (170, 180) which are mounted in the vehicle; an operation unit (110) that is configured to accept an operation of selecting content that is displayed on some or all of the plurality of display units; a determination unit (120) that determines a sitting position of a person who operates the operation unit; and a display control unit (130) that is configured to cause any one of the plurality of display units to display content on the basis of an operation that is accepted by the operation unit and a determination result of the determination unit. In a state in which content is displayed on any one of the plurality of display units, in a case where an operation of performing display of new content is accepted by the operation unit, the display control unit is configured to change a display aspect of the content that is already displayed on the basis of a determination result of the sitting position by the determination unit.
US10780780B2 Self-balancing two-wheeled vehicle
In an aspect, a self-balancing two-wheeled vehicle is provided, having a body, and first and second wheels rotatably coupled to the body. The second wheel has at least one lateral roller rotatable about an axis that is one of oblique and orthogonal to a rotation axis of the second wheel. At least one motor is coupled to the second wheel to control rotation of the second wheel and the at least one lateral roller. At least one sensor is coupled to the body to generate orientation data therefor. A control module is coupled to the at least one motor to control operation thereof at least partially based on the orientation data generated by the at least one sensor.
US10780779B2 Behavior control apparatus for a four-wheel drive vehicle
A behavior control apparatus for a four-wheel drive vehicle comprising a driving unit, front and rear wheel driving torque transmission paths that transmit driving torques of the driving unit to front and rear wheels, respectively, and control unit. The rear wheel driving torque transmission path includes a speed increasing device for increasing speed of the rear wheels relative to the front wheels and two clutches for the left rear w heel and right rear wheel disposed between the speed, increasing device and the left rear wheel and the right rear wheel, respectively. The control unit engages the clutch on the turning inside when the vehicle is in oversteer state during turning under braking in a situation where the two clutches are disengaged.
US10780768B2 Torque rod
A torque rod including: a rod member; and a rubber bushing provided at a lengthwise end of the rod member, wherein the rubber bushing includes an inner axial member, an outer tubular member, and a rubber elastic body connecting the inner axial member and the outer tubular member with each other, the lengthwise end of the rod member is fixed to the inner axial member of the rubber bushing constituted by a part separate from the rod member, and a stopper to limit a relative displacement amount of the inner axial member and the outer tubular member in the rubber bushing is constituted in contact sections of the rod member and the outer tubular member.
US10780766B2 Vehicle door assemblies
A vehicle door assembly according to an exemplary aspect of the present disclosure includes, among other things, a first door, a second door and a first hinge assembly connected to the first door and the second door. The first door is movable between a first position and a second position about the first hinge assembly, and in the second position, the first door is received against the second door.
US10780760B2 System and method for relieving cabin pressure in a motor vehicle
A cabin pressure relief system for a motor vehicle includes a pressure relief valve and a control module. The control module is configured to open the pressure relief valve when an access door of the motor vehicle is opened and close the pressure relief valve in response to a specific event.
US10780758B2 Shock-absorbing damper with a spring plate fastened thereto, and method for the fastening of a spring plate to a shock-absorbing damper
A device for damping vibrations may comprise a hollow damper tube, a piston rod with a piston fastened thereto, at least one spring plate, and at least one securing element. The piston may be disposed within the damper tube, and the spring plate may be disposed outside the damper tube. To achieve a reliable connection between the spring plate and the damper tube in a cost-effective manner, the spring plate may be connected to the damper tube in both a force-fitting manner and a form-fitting manner. The present disclosure further concerns motor vehicles that employ such devices, as well as methods for fastening spring plates to damper tubes.
US10780756B1 Purging dust boot
A boot with a body cavity that protects a moveable joint and retains lubricant associated with the joint is disclosed. The wall of the boot body includes a venting aperture that is protected by a surrounding barrier structure.
US10780751B2 Hitch pin lock systems
A hitch system is described for coupling an object to a vehicle hitch. The hitch system can have a connector adapted to connect to a vehicle hitch having a connector channel that passes through the connector and has an internal threaded section; a lock rod having, a first section wherein at least a portion of the first section is threaded wherein the internal threaded section of the connector are adapted to receive the threads of the first section of the lock rod and a second section; and a locking member having a first locking member channel having an inside diameter and an outside diameter wherein the inside diameter of the locking member channel is smaller than the diameter of the second section and a lock to move between a locked position and an opened position wherein the second section of the lock rod is secured to the locking member when the second section is disposed within the locking member channel and the lock is in the locked position and is removable when the lock is in the opened position.
US10780750B2 Method for determining a wheel tire ground print
Method of determining the footprint of a tire on the ground, using devices already installed in standard production tires. Since the frequency of the transmitter clock present in a wheel unit is perturbed by mechanical vibrations when the tire contacts the ground, the frequency variations of the reference clock are representative of the value of the footprint. The method therefore includes determining the footprint on the ground of a tire of a wheel by measuring continuously, as a function of time, a signal representative of the variations in frequency of the reference clock supplied at the output of the time control device; determining a time interval during which the frequency variations of the reference clock occur; and, on the basis of the rotation speed of the tire, deducing therefrom an angular range of contact (Θ) corresponding to the footprint between the ends representing the ground contact length of the tire.
US10780749B2 Systems and methods for vehicle TPMS localization
Method and apparatus are disclosed for localizing vehicle TPMS sensors. An example vehicle includes a plurality of TPMS sensors, an antenna, and a processor. The processor is configured for determining signal strength values between each of the plurality of TPMS sensors and the antenna, and based on the signal strength values, determining a location of each of the plurality of TPMS sensors.
US10780747B2 Tire structure and combining structure thereof
Provided is a tire structure capable of being combined with a rim, and the tire structure includes an air tube, a core provided on the air tube, and a tire outer layer provided on the core, and the core includes a body part positioned above a transverse diameter of the air tube and a wing part positioned under the transverse diameter of the air tube, and a lower end of the wing part is placed under an upper surface of the rim.
US10780741B2 Rubber composition for tire treads and tire manufactured by using the same
Disclosed are a rubber composition for tire treads which includes raw rubber including a natural rubber, a solution-polymerized styrene butadiene rubber and a neodymium butadiene rubber, a reinforcing filler including highly dispersible silica and carbon black and a natural oil having an unsaturated fatty acid content of 60 to 90% by weight, and a tire manufactured from the same. The tire manufactured from the rubber composition for tire treads according to the embodiment of the present invention can exhibit excellent braking performance, abrasion resistance and durability.
US10780739B2 Retractable wheel assembly for raising and lowering a gaming machine cabinet
An electronic gaming machine includes a cabinet having an internal frame and a pair of retractable wheel assemblies mechanically coupled to the internal frame. Each retractable wheel assembly includes a first retractable wheel, and a second retractable wheel. The first retractable wheel and the second retractable wheel are movable between a retracted position and an extended position. The first and second retractable wheels of each of the pair of retractable wheel assemblies support the cabinet above an external surface when each are in the extended position, thereby facilitating movement of the cabinet across the external surface. Further, the first and second retractable wheels of each of the pair of retractable wheel assemblies allow the cabinet to contact the external surface when each are in the retracted position.
US10780731B2 Mail creation method and image forming system
A mail creation method includes forming an address, forming an image, folding, inserting, sealing, and fixing a voucher. In the forming of the address, an image forming section forms the address on an envelope. In the forming of the image, the image forming section forms the image on paper. In the folding, a folding section folds the paper having the image formed thereon. In the inserting, an enclosing section inserts the folded paper into the envelope having the address formed thereon. In the sealing, the enclosing section seals the envelope having the folded paper inserted therein. In the fixing of the voucher, a voucher fixing section fixes the voucher to the sealed envelope. The voucher indicates that postage has been paid.
US10780728B2 Secure article comprising a combined image and/or a revelation screen
A secure article including a revelation screen and a combined image, or a set comprising a secure article and another object. The secure article including one of the revelation screen and the combined image and the object comprising or making up the other of the revelation screen and the combined image. The combined image including a plurality of overlapping images. The combined image including a periodic alternation of overlapping image elements in a first direction. The revelation screen including a masking screen element alternating periodically with a non-masking screen element in a second direction. The size of the non-masking screen elements in the second direction is greater than the size, in the first direction, of at least one element of overlapping images, the revelation screen making it possible to observe various revealed images by moving the revelation screen in relation to the combined image and/or by changing the observation angle.
US10780725B2 End paper arrangement and method for forming the front and back end paper of a book
An end paper arrangement and method for forming the front and back end paper of a book wherein the end paper arrangement comprises an inner sheet and outer sheet which are fastened on one side against each other over at least one area so that an unfastened area remains between the fastened areas. The unfastened area forms a tunnel for the spine of the book. On that side of the inner sheet which is opposite to the fastened side there is an adhesive surface on both edge parts, and there is an adhesive-free area between the adhesive surfaces. On the side of the outer sheet which is opposite to the fastened side, there is an adhesive surface on both edge parts, and there is an adhesive-free area between the adhesive surfaces. The method performs the assembly set forth in the arrangement.
US10780723B2 Electric apparatus and control method therefor
An apparatus for controlling movement of a target object generates a first operation quantity for first feedback control, and determines a second operation quantity for second feedback control in accordance with which of plural regions obtained by dividing a two-dimensional space defined by two variables of the first and second state quantities includes the first and second state quantities. The plural regions include first, second and third regions, the first region being provided between the second and third regions. The second operation quantity is determined so that the second operation quantity when the first and second state quantities are located in the first region is less than the second operation quantity when the first and second state quantities are located in the second region or the third region.
US10780720B2 Platen conveyance device and platen moving device
A platen conveyance device includes a platen, a first platen support portion, a first conveyance path, a second platen support portion, a second conveyance path, and a platen moving portion. The platen includes a neckline guide portion. The first platen support portion supports the platen. The first conveyance path movably guides the first platen support portion in a first direction. The second platen support portion supports the platen. The second conveyance path movably guides the second platen support portion in the first direction. The platen moving portion moves the platen, which is supported by one of the first platen support portion and the second platen support portion with the neckline guide portion positioned on a first side in the first direction, to the other of the first platen support portion and the second platen support portion with the neckline guide portion positioned on the first side.
US10780719B2 Inkjet printing device and inkjet printing method
An inkjet printing device includes an ink container accommodating a non-aqueous clear ink containing a resin and an organic solvent, a discharging head to discharge the non-aqueous clear ink directly or indirectly onto a substrate to form printed matter; and a heating device to heat the substrate, wherein the following relationship is satisfied: Tlow (° C.)>Thigh (° C.), where Tlow represents the temperature of the substrate that the heating device is heating during printing in a low gloss printing mode in which the non-aqueous clear ink is directly or indirectly discharged and attached to the substrate to impart low gloss to the printed matter and Thigh represents the temperature of the substrate that the heating device is heating during printing in a high gloss printing mode in which the non-aqueous clear ink is directly or indirectly discharged and attached to the substrate to impart high gloss to the printed matter.
US10780714B2 Mandrel for printing necked cans
A mandrel wherein a portion of the mandrel body outer surface is conical; i.e., flared outwardly, is provided. In this configuration, the necked can is drawn against the conical portion of the mandrel body outer surface while a generally cylindrical portion of the mandrel body extends into the can. Further, the space between the cylindrical portion of the mandrel body and the can is pressurized so as to resist deformations in the can during the decorating process. In an exemplary embodiment, the mandrel includes an elongated mandrel body with an outer surface, a proximal, first end, a proximal medial portion, a distal medial portion, and a distal, second end and having an axis of rotation. The mandrel body outer surface includes an elongated conical portion; the mandrel body outer surface conical portion is disposed adjacently about the mandrel body first end.
US10780706B2 Discharging device and discharging method
Provided is discharging device including liquid droplet discharging unit configured to discharge liquid droplet containing a light-emitting particle that undergoes luminescence in response to irradiation of light, light irradiating unit configured to irradiate liquid droplet discharged by liquid droplet discharging unit with the light, light detecting unit configured to detect luminescence by light-emitting particle contained in liquid droplet in response to irradiation of the light emitted by light irradiating unit, and average particle number calculating unit configured to determine presence/absence of light-emitting particle in liquid droplet based on whether light detecting unit has detected luminescence by light-emitting particle, and calculate average particle number, which is average, among all liquid droplets discharged, in number of light-emitting particles contained per liquid droplet, based on ratio of liquid droplets containing no light-emitting particle relative to all the liquid droplets discharged, the ratio being calculated based on the presence/absence of light-emitting particle.
US10780705B2 Fluid ejection device
A fluid ejection device includes a fluid slot, two laterally adjacent fluid ejection chambers each having a drop ejecting element therein, a fluid circulation path communicated with the fluid slot and each of the two laterally adjacent fluid ejection chambers, and a fluid circulating element within the fluid circulation path, with the fluid circulating element laterally adjacent at least one of the two laterally adjacent fluid ejection chambers, and the two laterally adjacent fluid ejection chambers to substantially simultaneously eject drops of fluid therefrom such that the drops of fluid are to coalesce during flight.
US10780704B2 Ink-jet print head assemblies with a spacer surrounding an ink fill port and method of manufacturing
A print head assembly for an ink-jet printer operable with a continuous ink supply system is disclosed, with an ink compartment, a foam insert, an ink fill port, and a spacer. The ink fill port receives ink fed from an external supply and to be printed by the print head assembly. The ink compartment stores the ink to be printed. The foam insert is in the ink compartment and takes up the ink to be stored. The spacer extends into the ink compartment, provides for the formation of a clearance between the foam insert and the ink fill port and surrounds the ink fill port either completely or with one or more gaps having a gap width. The gap width of none of the gaps presents an aperture angle of more than 25% of 36° with respect to a center of the ink fill port.
US10780699B2 Printhead with removable printhead cover
In one example in accordance with the present disclosure a printhead is described. The printhead includes a number of nozzles to deposit an amount of fluid onto a print medium and an ink delivery system to deliver the amount of fluid from an ink tank to the number of nozzles. The printhead also includes an attachment feature to removably couple a removable printhead cover to the printhead. The printhead further includes a removable printhead cover removably coupled to the printhead at the attachment feature.
US10780695B2 Ink jet printing
Printheads and printers are described herein. In one example, a printhead includes a number of drop generators disposed in a first array and a second array. The drop generators in both the first array and the second array are spaced one dot pitch apart perpendicular to the motion of a print medium, and alternate between a high drop weight (HDW) drop generator and a low drop weight (LDW) drop generator. Each drop generator in the first array is in a line of the motion of the print medium with a corresponding drop generator in the second array, wherein each HDW drop generator in the first array is in line with an LDW drop generator in the second array, and each LDW drop generator in the first array is in line with an HDW drop generator in the second array.
US10780693B2 Inkjet head
According to one embodiment, an inkjet head includes a pressure chamber connected to a nozzle, an actuator corresponding to the pressure chamber and configured to change a volume of the pressure chamber, and a drive circuit configured to drive the actuator causing two or more ink droplets to be consecutively discharged from the nozzle. The drive circuit applies in sequence a first drive waveform for expanding the pressure chamber, a second drive waveform having a first pulse width, a third drive waveform for releasing the pressure chamber from an expanded state, a fourth drive waveform having a second pulse width, and a fifth drive waveform for contracting the pressure chamber.
US10780690B2 Liquid ejecting apparatus and drive signal generation circuit
A liquid ejecting apparatus includes a drive circuit that outputs a drive signal, a piezoelectric element that includes a first electrode to which the drive signal is supplied and a second electrode to which a reference voltage signal is supplied and that is displaced by a potential difference between the first electrode and the second electrode, a cavity that is filled with a liquid ejected from a nozzle according to the displacement of the piezoelectric element, a vibration plate that is provided between the cavity and the piezoelectric element, a detection circuit that detects whether or not a voltage variation of the drive signal is within a predetermined range, and a determination circuit that determines whether or not the drive signal is normal based on a detection result of the detection circuit.
US10780688B2 Highly wrinkled metal thin films using lift-off layers
Described are fabrication methods of highly wrinkled metal thin films for applications in electronics such as wearable devices, strain sensors, and capacitive sensors.
US10780686B2 Composite panel, composite material, impregnator and method for manufacturing a composite panel
An impregnator for impregnating a fabric layer comprising: a chamber, the chamber being structured and arranged so as to retain a binding composition in a fluid state; a first opening being structured and arranged so as to allow the fabric layer entering the chamber in a dry state from a top portion of the chamber to be dived into the binding composition; and a second opening extending along the longitudinal axis of a bottom portion of the chamber, the second opening being structured and arranged to allow the fabric layer to exit from the bottom portion of the chamber in an impregnated state, the second opening comprising a first lip structured and arranged to be in contact with a first surface of the fabric layer and a second lip structured and arranged to be in contact with a second surface of the fabric layer.
US10780685B2 Hard coat laminated film
A hard coat laminated film according to at least one embodiment has, from the surface layer side, a first hard coat and a transparent resin film layer. The first hard coat is formed from a coating material including: (A) 100 parts by mass of a polyfunctional (meth)acrylate; and (B) 1-100 parts by mass of an N-substituted (meth)acrylamide compound. The transparent resin film has a first hard coat forming surface which is a poly(meth)acrylic imide resin. A hard coat laminated film according to another embodiment has, from the surface layer side, a second hard coat, the first hard coat and the transparent resin film layer. The second hard coat is formed from a coating material which includes: (A) 100 parts by mass of a polyfunctional (meth)acrylate; (E) 0.01-7 parts by mass of a water repelling agent; and (F) 0.01-10 parts by mass of a silane coupling agent; without inorganic particles.
US10780683B2 Modified polyester sheet having snapability
The present invention is directed to a fracturable thermoformable packaging sheet comprising at least one thermoplastic layer having a thickness of between 10 mil and 50 mil which is composed of a polymer matrix of between 35% (wt.) to 77.5% (wt.) relative to the total weight of the thermoplastic layer of a substantially amorphous aromatic polyester. Incorporated into this polymer matrix of the at least one thermoplastic layer is an inorganic filler which is present in an amount of between 22% (wt.) to 50% (wt.) relative to the total weight of the thermoplastic layer. The inorganic filler is encased in a carrier resin which is present in an amount of between 0.5% (wt.) to 15% (wt.) relative to the total weight of the thermoplastic layer. The fracturable thermoformable packaging sheet of the present invention may be used to form thermoformed packages having a single product cavity with a snap-open tab or covering and multi-pack type packages having multiple single-serve product cavities where each individual cavities can be easily separated from each other by simply breaking the flange connecting two or more cavities. Each of these packages may optionally include a partial cut and/or crease Sine extending across a portion of the package to facilitate the snapping apart of the two sections of the package.
US10780680B2 Systems and methods for composite radius fillers
A composite radius filler material is provided. The composite radius filler includes a resin, a first group of fibers dispersed within the resin, and a second group of fibers dispersed within the resin. The first group of fibers has a first length configured to facilitate orientation in a longitudinal direction. The second group of fibers has a second length that is shorter than the first length, with the second group of fibers configured to facilitate random orientation in a transverse direction.
US10780679B2 Laminate, method for manufacturing laminate, semiconductor device, and method for manufacturing the semiconductor device
Provided is a laminate that excels in adhesion among a plurality of resin layers formed as insulating layers containing polyimide and so forth, a method for manufacturing the laminate, a semiconductor device, and, a method for manufacturing the semiconductor device. The laminate comprises a substrate, and at least two resin layers, each of the resin layers is independently brought into contact, in at least a part of the surface thereof, with other resin layer, and the layers independently has a Young's modulus exceeding 2.8 GPa and not exceeding 5.0 GPa, and, an elongation after fracture exceeding 50% and not exceeding 200%, and further has a three-dimensional radical crosslinked structure, and at least one of the resin layers contains at least either polyimide or polybenzoxazole.
US10780678B2 Composite sandwich structure
The invention relates to a composite sandwich base panel for a Unit Load Device. The panel comprises an upper surface layer comprising fibre reinforcement material, a lower surface layer comprising fibre reinforcement material, and a central core section where at least the majority comprises a plurality of particles bound in a matrix material. The upper surface layer and lower surface layer are provided with a matrix material to bind them to the central core section.
US10780677B2 Composite structure exhibiting energy absorption and/or including a defect free surface
Embodiments described herein relate to a composite structures or sandwiches that may have a relatively high bending stiffness and may have a relatively light weight as well as related methods of use and fabrication of the composite sandwiches. For example, a composite sandwich may include a core structure sandwiched between a two composite skins.
US10780675B2 Gas barrier film, optical film, and flexible display
This invention provides a gas barrier film, which can suppress blocking and winding deviation, and an optical film using the gas barrier film.The gas barrier film includes a flexible substrate and an inorganic thin film layer formed on at least one surface of the flexible substrate. A static friction coefficient between one surface of the gas barrier film and the other surface is not less than 0.85 and not more than 2.0, and when a 50 mm-square portion cut from the gas barrier film is placed on a horizontal surface such that a central portion of the 50 mm-square portion is in contact with the horizontal surface, an average value of distances from the horizontal surface to four corners of the 50 mm-square portion is not more than 2 mm.
US10780667B2 Machine and method for forming capsules with pleated capsule body
The present invention describes a method and a machine for the formation of a capsule (100) for producing beverages in which the capsule (100) comprises a pleated capsule body (101) and a reinforcing element (102). The method comprises the following steps: a step of forming the pleated capsule body (101) of the capsule (100) in a first station (110); a step of supplying the reinforcing element (102) in a second station (111) different from the first station (110); a step of transporting the pleated capsule body (101) from the first station (110) to the second station (111); a step of insertion in the second station of the pleated capsule body (101) in the reinforcing element (102); a step of coupling between the pleated capsule body (101) and the reinforcing element (102) in the second station (111).
US10780666B2 Washable, waterproof, sealable and reusable storage bags
Disclosed are embodiments of a versatile storage bag and methods of making same. The versatile storage bag may have first and second sidewalls, a double-locking closure mechanism with a first closure element extending along the first sidewall and a second closure element extending along the second sidewall, each closure element having a channel and an elongated member configured for interlocking with one another. A double-seal along three sides of the first sidewall and the second sidewall form a gusset between two seals, leaving an opening through the double-locking closure mechanism. Corner seals may be formed at the corners of the first and second sidewalls, further reinforcing the double-locking closure mechanism for an airtight and hence waterproof seal. The versatile storage bag may be made of a food-grade polyethylene vinyl acetate blend, approximately 90% or less ethylene vinyl acetate and approximately 10% or less polyethylene.
US10780665B2 Dynamically adjustable sensors for trash compactors and receptacles
Systems, methods, and computer-readable storage media for dynamically adjusting sensors for use in compactors and receptacles. A receptacle first sends a signal from a transmitter on a first module in a receptacle to a receiver on a second module in the receptacle, wherein the first module is located on a first inner wall of the receptacle and the second module is located on a second inner wall of the receptacle, and wherein at least part of the first module and the second module is located a distance above a bin inside the receptacle. Next, the receptacle determines a signal-detection characteristic including a signal detection status or a number of signal pulses associated with a signal detection. Based on the signal-detection characteristic, the receptacle determines an operating condition of the receptacle, the operating condition including a fullness level or an obstruction level associated with the first or second sensors.
US10780661B2 Molding element for manufacturing a noise reducing tread
The molding element has a molding surface forming a contact face and a groove forming rib portion forming the groove comprising two opposed rib side faces and a rib top face connecting two rib side faces. The groove forming rib portion provides at least one cavity opening to the rib top face and to at least one of the rib side faces. The cavity has two opposed cavity faces. The molding element comprises at least one cutting means extending and/or projecting in a direction the groove forming rib portion extends for cutting a material filled in the cavity during demolding.
US10780660B2 Tire sealant and tire repair kit
An object of the present invention is to provide a tire sealant that excels in injectability while maintaining sealing performance and storage performance at an excellent level, and to provide a tire repair kit. Provided are a tire sealant containing a rubber latex and an anti-freezing agent, wherein the anti-freezing agent contains glycerin and at least one type of glycol-based compound selected from the group consisting of glycols and glycol ethers; the content of the glycerin is from 2 to 50 mass % of the total amount of the anti-freezing agent; and a tire repair kit that includes the tire sealant.
US10780658B2 Heating system for composite rework of aircraft
A method and apparatus comprising a laser unit and a controller. The laser unit is configured to generate a number of laser beams. The controller is configured to operate the laser unit to generate the number of laser beams resulting in a desired level of heating of a composite patch that cures the composite patch on a composite structure.
US10780652B2 Printing method for color compensation of 3D printer
A printing method for color compensation adopted by a 3D printer (1) having a 3D nozzle (121) and a 2D nozzle (122) is disclosed. The printing method includes following steps of: controlling the 3D nozzle (121) to print a slicing object (2) of the 3D object upon a printing platform (11) according to a route file; controlling the 2D nozzle (122) to perform coloring on the printed slicing object (2) according to an image file; controlling the 2D nozzle (122) and the printing platform (1) to rotate relatively for creating an angular transposition between the 2D nozzle (122) and the printing platform (1) after the slicing object (2) is colored completely; and, controlling the 2D nozzle (122) to again perform coloring on the colored slicing object (2) after the 2D nozzle (2) and the printing platform (11) rotated relatively.
US10780645B2 Method and apparatus for creating pouches or bags with multiphase sealing
A method and apparatus for forming pouches and/or bags is disclosed. A seal and/or insert is crushed using a multiphase sealer or crusher.
US10780640B2 Multiple image projection system for additive manufacturing
An additive manufacturing system, and associated methods, comprise an image projection system comprising a plurality of image projectors that project a composite image onto a build area within a resin pool. The composite image comprises a plurality of sub-images arranged in an array. The properties of each sub-image and the alignment of the position of each sub image within the composite image can be adjusted using a stack of filters comprising: 1) an irradiance mask that normalizes irradiance, 2) a gamma adjustment mask that adjusts sub-image energy based on a reactivity of the resin, 3) a warp correction filter that provides geometric correction, and 4) an edge blending bar at one or more sub-image edges.
US10780639B2 Irradiation device for an apparatus for additively manufacturing three-dimensional objects
Irradiation device (6) for an apparatus (1) for additively manufacturing three-dimensional objects (2) by successive layerwise selective irradiation and consolidation of layers of a build material (3) which can be consolidated by means of an energy beam (4), the irradiation device (6) being adapted for a successive layerwise selective irradiation and consolidation of layers of a build material (3) by means of at least one energy beam (4), the irradiation device (6) comprising: —a plurality of beam generating units (7a-7c) each being adapted to generate at least one energy beam (4a-4c) of given beam properties, each beam generating unit (7a-7c) being couplable or coupled a with at least one beam guiding element (8a-8c), —a plurality of beam guiding elements (8a-8c), in particular beam guiding fibers, each beam guiding element being (8a-8c) couplable or coupled with at least one beam generating unit.
US10780637B2 3-D printer in polar coordinates
This invention is in the field of automated 3D printing of buildings or structures and method of its operation. A 3D printer having an extendable boom arm with an extruder for extruding a concrete-based chemical solution moves with translational and rotational motion in an XOY plane. The extendable boom arm is mounted such that it is capable of height adjustment in a XOZ plane. The invention also regards a method for automated 3D printing of a building or structure using the 3D printer.
US10780633B2 3D printing
Compositions and methods for 3D printing are described herein. In an example, a composition for 3D printing can comprise a build material comprising at least one polymer and at least one first electron donor compound; and a fusing agent comprising (i) a metal bis(dithiolene) complex, (ii) at least one surfactant, at least one second electron donor compound, or combinations thereof, (iii) a polar aprotic solvent, and (iv) water. The at least one first electron donor compound and the at least one second electron donor compound can be the same or different.
US10780631B2 Compositions and methods for additive manufacturing
A composition for additive manufacturing of an article may include a base material, a functional particulate having at least one of an acicular morphology and a platy morphology, and binder. The functional particulate may increase a strength property of the article manufactured with the composition as compared to the strength property of the article manufactured with the composition being devoid of the functional particulate. A method of manufacturing an article via additive manufacturing may include providing a first layer of a powder composition. The powder composition may include a base material, a functional particulate, and binder. The method may also include binding the first layer of powder composition in a predetermined pattern to form a hardened two-dimensional shape including the powder composition, and successively providing additional layers of the powder composition and binding the respective layers to form the article.
US10780622B2 Blown film line and method for operating a blown film line
A blow film line and a method for operating the same relates to improving the flow rate in conventional blow film lines without compromising the production quality.The inner cooling body shows an air outlet path, with a cooling ring being embodied in a height-adjustable fashion, with a controller positioning the cooling ring in a lower area of the inner cooling body for the start-up of the facility. The cooling ring is positioned in the upper area of the air outlet path of the inner cooling body in order to achieve the steady-state production.
US10780621B2 Quick-change fused filament fabrication nozzle assembly
The present invention provides a system and method for quickly removing and installing a filament tube and nozzle in an FFF extrusion system. The system utilizes a primary manifold that includes a cooling block, a heating block and a quick-change mechanism. This primary manifold is adapted to mate a filament tube/nozzle assembly. The quick-change mechanism, which in a particular embodiment utilizes a recessed biased-bearing arrangement, enables the filament/nozzle assembly to be removed and inserted without the use of any tools, and without causing any significant downtime for the FFF extrusion system. Once removed, the filament tube/nozzle assembly can be refurbished by a technician, trained so as not to over torque the tube/nozzle threaded interface. This refurbishment (typically consisting of a cleaning and the installation of a new nozzle) could be accomplished “off-line”, without any impact on the continued use of FFF extrusion system.
US10780616B2 Methods of forming composite structures
A method of forming a composite structure including coupling a plurality of components together forming a joint: wherein the plurality of components are oriented to form a radius gap therebetween: forming a filler structure that includes a closed cell foam core that has a porosity within a range defined between about 20 percent and about 40 percent by volume of the closed cell foam core and wherein the closed cell foam core is formed from a silicone-based material. The method also includes positioning the filler structure in the radius gap: and applying at least one of heat or pressure to the plurality of components and the filler structure.
US10780614B2 System and method for forming stacked materials
A system for forming stacked material includes a housing defining an interior space. The housing includes a bottom wall and a side wall coupled to the bottom wall. At least one tool is configured to shape the stacked material. The at least one tool is disposed within the interior space. A membrane extends at least partially over the bottom wall and is spaced a distance from the bottom wall. The membrane is configured to move towards the bottom wall. At least one intensifier mechanism is disposed in the interior space and is configured to induce a force against a portion of the stacked material and against the at least one tool as the membrane is moved towards the bottom wall.
US10780613B2 Reproduction of a stem cell niche of an organism and method for the generation thereof
The present invention relates firstly to a method for reproducing a stem cell niche of an organism. The invention further relates to a reproduction of a stem cell niche of an organism. According to the invention, an image of a tissue of an organism is generated, which tissue comprises at least one stem cell niche. The image is filtered in order to obtain a structural pattern of the imaged stem cell niche. In a further step, a lithographic mask is generated from the structural pattern. According to the invention, a starting material of a substrate is structured by means of indirect or direct application of the lithographic mask, whereby a structured substrate is obtained which represents the reproduction of the imaged stem cell niche of the organism. The reproduction can be characterised as biolithomorphic.
US10780609B2 Fiber-reinforced composite articles and methods of making them
Methods of making prepregs are described. The methods include the steps of forming a fiber-containing substrate, and contacting the fiber-containing substrate with a resin mixture. The resin mixture may include polymer particles mixed in a liquid medium, and the polymer particles may be coated on the fiber-containing substrate to form a coated substrate. The liquid medium may be removed from the coated substrate to form the prepreg. The prepregs may be used to make fiber-reinforced articles.
US10780608B2 Process for preparing moulded articles from fibre-reinforced composite materials—II
The present invention relates to low or zero-tack composite materials such as pre-pregs and their use in automated manufacturing, particularly robotic pick and place. The present invention further relates to an automated process for preparing an article, particularly a molded article, from a fiber-reinforced composition material.The molded articles prepared by the process described herein are particularly suitable as components for transport applications, and particularly the automotive industry. The automotive components prepared by the present invention are particularly suitable as mid- or high-volume automotive parts, in which cost and speed of production are paramount. The present invention provides a process in which the cutting and handling of pre-preg materials is greatly simplified, providing advantages of efficiency and economy. The lay-up time according to the present invention is significantly reduced, allowing a reduction in the unit cost per component and/or allowing the high volume of component production desired in the automotive industry.
US10780601B2 Blade cleaning for automated fiber placement machines
Systems and methods are provided for cleaning composite fabrication machinery. One embodiment is a method for cleaning of a composite application machine, comprising: displacing an anvil of a head of an Automated Fiber Placement (AFP) machine from an operation location relative to a cutter, cleaning at least one of the cutter and the anvil, and relocating the anvil to the operation location relative to the cutter.
US10780600B2 Method for cutting gate formed on molded article
A method for automatically cutting off a material passage part while reducing manufacturing cost and cycle time. This method includes preparing a cutting device capable of moving in an automatic control coordinate system, placing the molded article without fixing the molded article, detecting a shape of the molded article by a sensor, acquiring a position of the material passage part in the coordinate system, determining a position of a cut spot in the material passage part as a target position in the coordinate system, moving the cutting device in the coordinate system and disposing the cutting device on a work position for cutting the cut spot, and cutting the cut spot by the cutting device arranged on the work position.
US10780589B2 Shape compliant electroadhesive gripper
Disclosed herein is a shape compliant electroadhesive gripper for picking up an atypical object. The shape compliant electroadhesive gripper comprises a body, and an electroadhesive module disposed on the body and including an electrorheological elastomer, wherein, when a voltage is not applied, a shape of the electroadhesive module is deformed according to a shape of an external object coming into contact with the electroadhesive module, and when the voltage is applied, rigidity of the electrorheological elastomer is increased to maintain the shape of the electroadhesive module, and when the voltage is applied to the electroadhesive module, electroadhesion is made due to an electrostatic force generated between the electrorheological elastomer and the adjacent external object.
US10780587B2 Operating device for controlling or programming a manipulator
An operating device for controlling or programming a manipulator with six degrees of freedom that can be controlled independently from one another. The operating device includes three input arrangements which are each configured to specify a movement of the manipulator along an x-axis, y-axis or z-axis of the manipulator, and to specify a rotation of the manipulator about the x-axis, y-axis or z-axis of the manipulator. The three input arrangements are thereby respectively aligned along one of three main axes of the operating device.
US10780586B2 Horizontal articulated robot with bevel gears
A horizontal articulated robot may include a hand; an arm having at least two arm portions including a supporting-arm portion to which said hand is rotatably joined and a supported-arm portion to which the base end of said hand-side arm portion is rotatably joined; a main body portion; and a rotation mechanism structured to rotate said supported-arm portion. The rotation mechanism may include a motor which is arranged such that an axial direction of an output shaft of the motor coincides with a horizontal direction; a Harmonic Drive (registered trade mark) wave-motion gearing device structured to reduce the power of said motor; a first bevel gear coupled to said output shaft; and a second bevel gear coupled with a wave generator of said Harmonic Drive (registered trade mark) wave-motion gearing device and which meshes with said first bevel gear.
US10780583B2 System and method of controlling robot
A robot control system includes: an interface configured to receive a user input; a controller configured to generate a motion command corresponding to the user input and a motion command group including the motion command, and generate hardware interpretable data by analyzing the motion command; and a driver configured to drive a motion of at least one hardware module based on the hardware interpretable data to be interpreted by the at least one hardware module.
US10780574B2 Link actuating device
A distal end side link hub is coupled to a proximal end side link hub via three or more link mechanisms. Each link mechanism has a proximal side end link member, a distal side end link member, and an intermediate link member. The proximal side end link member has a bent portion and rotation shaft mounting portions. A rotation shaft is mounted to the rotation shaft mounting portion. A bevel gear, forming a part of a gear mechanism for transmitting rotary motion of a posture control actuator to the proximal side end link member, is mounted on the rotation shaft mounting portion and disposed in a space between two virtual planes obtained by extending a radially inner edge and a radially outer edge of one end of the bent portion in a longitudinal direction of the rotation shaft mounting portion.
US10780573B2 Surgical instrument housing, and related systems, and methods
A force transmission mechanism of a surgical instrument, which is configured to releasably engage with a drive interface device located at a patient side cart of a teleoperated surgical system, includes a housing. The housing is configured to cover one or more drive components of the force transmission mechanism. The housing includes a releasable coupling mechanism configured to releasably engage with the drive interface device. The housing and the releasable coupling mechanism are a monolithic construction.
US10780564B2 Power tool
A power tool, such as a rotary hammer or hammer drill, includes a first housing that contains a motor and a drive mechanism for linearly reciprocally driving a tool accessory, and a second housing that includes a handle, a first portion and a second portion. At least one elastic element connects the first and second housings such that the handle is biased away from the first housing. A first set of sliding contact surfaces is defined on or connected to the first housing and the first portion of the second housing. A second set of sliding contact surfaces is defined on or connected to the first housing and the second portion of the second housing. The first and second sets of sliding contact surfaces are located on opposite sides of the motor such that the rotational axis of the motor intersects the first and second sets of sliding contact surfaces.
US10780563B2 Electric power tool and method of controlling rotational speed of motor in electric power tool
An electric power tool according to one aspect of the present disclosure includes a main body, a motor, a tool holder configured to hold a tool bit, a hammer, a motion converter, a rotation transmitter, a first load detector, a second load detector, and a motor controller. The first load detector detects, based on information indicating a drive state of the motor, a load imposed from a work piece to the tool bit. The second load detector detects, based on information indicating a behavior of the main body, a load imposed from the work piece to the tool bit. The motor controller sets an upper limit of rotational speed of the motor to a predetermined no-load rotational speed in response to no-load on the tool bit being detected by both the first load detector and the second load detector.
US10780562B2 Hand tool device
A hand tool device has a tool spindle and a hammer mechanism which includes a hammer and at least one curve guide driving the hammer at least during a hammer drilling operation. The tool spindle has at least one bearing surface on which the hammer is movably supported in at least one operating state.
US10780559B2 Helical toothed driver and compatible fastener
A driver for applying torque to threaded fasteners has a plurality of teeth extending along and projecting outwardly from a longitudinal axis of a body on which the teeth are located. The teeth have a helical twist about the longitudinal axis. Each tooth has an angularly oriented engagement surface which is engageable with similarly angularly oriented surfaces within recesses in the head of a compatible fastener. When the driver engages the recesses torque applied to the driver draws the driver deeper into the recesses as the engagement surfaces react against and slide over the angularly oriented surfaces within the recesses. The torque also causes the fastener to turn and advance or retract depending upon the sense of the torque and the angles of the engagement surfaces and the angles of the surfaces within the recesses. The fastener and its method of manufacture are also disclosed.
US10780558B2 Tool extensions
Illustrative embodiments of tool extensions and methods of using such tool extensions are disclosed. In at least one illustrative embodiment, a tool extension may comprise a drive core configured to transfer rotational torque from a first end to a second end opposite the first end, where the first end is configured to be removably coupled to a tool to receive rotational torque from the tool, the second end is configured to be removably coupled to a fastener to supply rotational torque to the fastener, and the drive core is bendable between the first and second ends. The tool extension may further comprise a shell surrounding the drive core and containing an electro-rheological (ER) fluid configured to transition between a flexible state in which the shell permits bending of the drive core and a rigid state in which the shell resists bending of the drive core.
US10780550B2 System for blast-cleaning a barge deck, sides, and fittings
A system for blast-cleaning a barge deck, sides, and fittings providing for safety and avoidance of damage to the barge and to persons, where a barge is blast-cleaned with moving blaster units suspended from and traveling along an overhead track beam. In one embodiment, the moving blaster units are each controlled by a person in a moving operator capsule moving in tandem with a moving blaster unit. In another embodiment, the moving blaster units are robotically controlled from a robotic controller which has access to a three-dimensional plan of the barge, communicating with the robotic blaster units via RF antennae, and receiving real-time data from sensors located on each blaster head. Optionally, the system for blast-cleaning a barge can provide blaster-head cameras for real-time remote monitoring of operations and for recording of the operations allowing review of any issue, such as damage, that might arise.
US10780548B2 Surface plate cleaning apparatus
Disclosed is a surface plate cleaning apparatus which cleans the surfaces of surface plates having grooves. The surface plate cleaning apparatus includes an injection unit including an injection head, and at least one first injection nozzle and at least one second injection nozzle, and a moving unit configured to move the injection unit, the at least one first injection nozzle includes a first injection hole to inject a first cleaning solution, the at least one second injection nozzle includes a second injection hole to inject a second cleaning solution, a first separation distance from the upper surface of the injection head to the first injection hole and a second separation distance from the upper surface of the injection head to the second injection hole are different, and a first injection angle of the first cleaning solution and a second injection angle of the second cleaning solution are different.
US10780547B2 Machine tool
A machine tool includes a main shaft unit; a polishing head for processing a workpiece; and an unnecessary byproduct leakage preventing unit for preventing leakage of abrasive resulting from processing at or around a part of the workpiece, the part being processed, and wherein the unnecessary byproduct leakage preventing unit includes a cover provided separately from the polishing head, the cover having a structure that is open in three directions and that has walls in another three directions such that a protection space where to hold a part of the workpiece is defined, the cover for receiving the abrasive, and a movement mechanism for moving the cover so as to stay apart from the workpiece while the workpiece is not being processed and so as to have a part of the workpiece held in the protection space while the workpiece is being processed.
US10780546B2 Variable radius sanding block
A variable radius sanding block for sanding curved surfaces. The variable radius sanding block includes a base member and a plurality of variably sized radius patches. The base member is sized and proportioned to allow radius patches of varying size to be inserted, such that each of the radius patches will change the curvature of the sanding block upon insertion. The base member also having a folded flexible internal structure and a pair of flexible arms that facilitate insertion of radius patches of varying size. The radius patch includes a pair of grooves that receive the flexible arms of the base member and secure the base member to the radius patch.
US10780545B2 Device for removing tool joint edge burrs from cap opening of wheel
Disclosed is a device for removing tool joint edge burrs from a cap opening of a wheel. The cap opening of the wheel is an opening configured to mount a decorative cap of the wheel. The tool joint edge burrs are formed inside the cap opening of the wheel during machining the wheel and are a circular edge inside the cap opening. The device includes a cutter system which is configured to remove the tool joint edge burrs from the cap opening of the wheel by a first cutting edge and a second cutting edge of the cutter system.
US10780540B2 Workpiece clamp apparatus
A workpiece clamp apparatus includes: a robot arm having, at a distal-end portion thereof, a holding section for holding a workpiece; a hydraulic-fluid supply coupler provided at the distal-end portion of the robot arm; a hydraulic-fluid supply device for supplying a hydraulic fluid to the hydraulic-fluid supply coupler; a clamping device having a plurality of clamping members that grip the workpiece for machining with a machine tool; and a cylinder that has a hydraulic-fluid supply port to which the hydraulic-fluid supply coupler can be connected and that drives the clamping member in the workpiece-gripping direction as a result of the hydraulic fluid being supplied via the hydraulic-fluid supply port.
US10780534B2 Method and assembly installation for automatically joining components
A method and an assembly installation for implementing the method automatically joining components, in particular of a motor vehicle-side radiator grill with a chrome frame, and/or a radiator grill of this type with a chrome strip, in an assembly installation. In a first step, a second component is positioned on a first component or a third component is positioned on the second component thus forming a complete component. In a second step, the complete component is placed in a horizontally-oriented component receiving device of the assembly installation and in a third step an installation-side stamping device is guided in the direction of the complete component in such a manner, in particular lowered vertically, that the complete component is influenced in an end position of the stamping device with a pressing force that provides a latching arrangement or pressing arrangement of the components.
US10780532B2 Dolly device
A motorcycle frame rack enables a motorcycle frame to be repaired without removing many components from the motorcycle. A motorcycle is positioned on the motorcycle frame rack, secured in place and then the frame is adjusted using chains coupled to towers. A self-centering laser measuring system is able to be used to analyze and measure damage to the motorcycle frame. A dolly device is able to be used to support and transport a motorcycle, including a motorcycle without wheels.
US10780531B2 Solder ball, solder joint, and joining method
A solder ball includes 0.1% by mass or more and 10% by mass or less of In and a remainder of Sn. The ball has a yellowness (b*) in an L*a*b* color system of 2.8 or more and 15.0 or less and a lightness (L*) of 60 or more and 100 or less. The ball further includes at least one element selected from a group of 0% by mass or more and 4% by mass or less of Ag, 0% by mass or more and 1.0% by mass or less of Cu, 0% to 3% by mass in total of Bi and/or Sb, and 0% to 0.1% by mass in total of an element selected from a group of Ni, Co, Fe, Ge, and P, excluding a solder ball including 3% by mass of Ag, 0.5% by mass of Cu, 0.2% by mass of In and a remainder of Sn.
US10780528B2 Methods for residual stress reduction in additive manufacturing processes
A method for additively manufacturing an article includes providing or obtaining a build material, directing a first energy beam at the build material to raise the temperature of the build material above a melting point of the build material, and thereafter withdrawing the first energy beam to allow the build material to solidify into a first layer. The method further includes directing a second energy beam at the first layer, wherein the second energy beam differs from the first energy beam in that the second energy beam is of insufficient energy to cause melting of the first layer of build material and after directing the second energy beam at the first layer, providing additional build material over the first layer. The second energy beam will have an effect of reducing or eliminating residual stresses of each build layer. The energy of the second energy beam can be controlled using a thermal or optical feedback loop. Still further, the method includes directing a third energy beam at the additional build material to form a second layer that is metallurgically fused with the first layer. The process is repeated until an entire 3D shape of desired geometry is completed resulting in a part with reduced of free of residual stress or the potential of cracks within the 3D shape.
US10780517B2 Hydraulically driven dual operator welding system and method
Welding systems including a hydraulically driven welding power supply adapted to utilize hydraulic primary power to generate a first welding output for a first welding operation and a second welding output for a second welding operation are provided. Such welding systems may include control circuitry coupled to the hydraulically driven welding power supply and adapted to enable the hydraulically driven welding power supply to provide the first welding output and the second welding output at the same time to enable a first welding operator and a second welding operator to perform the first welding operation and the second welding operation, respectively, at the same time.
US10780514B1 Process for forming a single crystal superalloy wave spring
A process for forming a single crystal superalloy wave spring is provided. In one embodiment, the process may include machining a wave spring from a single crystal superalloy slab after optimizing its orientation using diffraction techniques so that the wave spring will exhibit optimal spring properties.
US10780513B2 Wire electrical discharge machining system
A wire electrical discharge machining system includes a securing device that is placed at a cut position where a workpiece on a holding unit has been cut by wire electrical discharge machining when the wire electrical discharge machining has been performed on the workpiece held on the holding unit to reach a predetermined position before the completion of machining and that individually attracts a cut-out portion from the workpiece and a remaining portion on the workpiece at the cut position where the workpiece has been cut, thereby securing the cut-out portion to the remaining portion, and a robot is configured to individually attract both the cut-out portion and the remaining portion with the securing device.
US10780511B2 Foldable miter saw and foldable method of miter saw
A foldable miter saw and folding method of miter saw are disclosed. The foldable miter saw includes a base unit, a workable, and a cutting unit. The cutting unit includes a support arm pivotally mounted on the worktable, a saw blade, and a driver. The miter saw folding method includes the step of biasing the cutting unit relative to the base unit and the step of rotating the support arm relative to the base unit and the worktable to change the cutting unit from a working position to a folded position, thus reducing the vertical space occupied by the cutting unit and facilitating delivery, storage and package of the foldable miter saw.
US10780509B2 Crayon carving device
Devices, kits, and methods for making a carved crayon are provided. In one aspect, a crayon carving device includes a base, a pantograph armature coupled to the base, a crayon positioner, and at least one guide template parallel to the crayon positioner. The kit may further include a wrapper removal mechanism configured to remove a wrapper from a crayon, such that the crayon carving device may be used on an exposed crayon surface.
US10780508B2 Setting tool for a drop-in anchor
The setting tool (1) has a first part (2) for driving in a drop-in anchor and a second part (3), placeable on the first part along an axis (8), for drilling a drill hole for the drop-in anchor. The first part (2) has an insertion end (5) for a percussive portable power tool, a plunger (6) having an impact surface (12) and a piece (16) of a rotary coupling. The second part (3) has a slip-on sleeve (20), which coaxially surrounds the plunger (6) and bears against the impact surface (12) of the plunger (6), a counterpart (33) for the rotary coupling and a drill bit (23) permanently connected to the slip-on sleeve (20).
US10780506B2 Tool and coated tool
A tool having a cutting edge that includes a sintered body containing cubic boron nitride. The sintered body integrally and inseparably includes an inner region and a binder phase enriched layer formed on at least part of a surface of the inner region. The inner region includes: 15-90 volume % of cubic boron nitride; and 10-85 volume % of a mixture of a binder phase and impurities. The binder phase enriched layer includes: 90-100 volume % of the binder phase and impurities mixture; and 0-10 volume % of cubic boron nitride; and the binder phase contains at least one kind selected from the group consisting of: at least one element selected from the group consisting of Ti, Zr, Hf, V, Nb, Ta, Cr, Mo, W, Al, Co, Ni and Si; and a compound of the element and at least one element selected from the group consisting of C, N, O and B.
US10780501B2 Method for manufacturing objects using powder products
A method for manufacturing a three-dimensional part. The method includes: performing partial densification processing on loose machining powder, to form a densified and sealed enclosure, where there is still loose machining powder accommodated inside the enclosure; and performing overall densification processing on the enclosure and the machining powder inside the enclosure, so as to implement metallurgical bonding between the machining powder inside the enclosure and the enclosure during the densification, thereby forming a target three-dimensional part.
US10780499B2 Powder feed for injection molding process and method for manufacturing porous metal
A method for manufacturing a porous metal with enhanced ability to bond to a plastic subsequently powder feed for injection molding process provides a powder feed to an injection molding process, to form a green embryo. The green embryo is sent into a sintering furnace for high-temperature sintering to obtain a blank sintered product. A chemical reagent is applied to form pores on the sintered product. The powder feed includes first and second metal powders evenly mixed. The second metal powder has a mass percentage of about less than 10% of a total mass of the powder feed for injection molding process. The first metal powder is corrosion-resistant. The second metal powder is readily corrodible.
US10780495B2 Gas-recycling device, additive manufacturing apparatus, and additive manufacturing method
A gas-recycling device according to an embodiment includes a particle remover, a liquid remover, and a supplier. The particle remover brings a mist of liquid into contact with a gas which includes particles and is discharged from an apparatus, to remove the particles from the gas. The liquid remover removes the liquid from the gas having passed through the particle remover. The supplier supplies the gas to the apparatus.
US10780492B2 Device and method for continuously producing a metallic workpiece in strip form
A method for continuously producing a strip-shaped metallic workpiece may involve introducing a molten mass into a casting region, solidifying the molten mass introduced into the casting region at least partially, and conveying the at least partially solidified molten mass out of the casting region. Hollow bodies may be added to the molten mass and encapsulated into the workpiece. Further, an apparatus for continuously producing a strip-shaped metallic workpiece may include a casting region into which a molten mass can be introduced and in which the molten mass introduced can solidify at least partially. The apparatus may also include a conveying device for conveying the molten mass out of the casting region, as well as a metering apparatus for adding hollow bodies to the molten mass.
US10780490B2 Electromagnetic brake system and method of controlling an electromagnetic brake system
An electromagnetic brake system for a metal-making process. The electromagnetic brake system includes a two-level magnetic structure, in particular an upper magnetic core structure configured to be mounted to an upper portion of a mold and a lower magnetic core structure configured to be mounted to a lower portion of a mold. Lateral coils on the upper magnetic structure are configured to be controlled to generate a first magnetic field in a first field direction and inner coils are configured to be controlled to generate a second magnetic field in a second field direction, simultaneously with the first magnetic field. The lower magnetic core structure has lower coils which are configured to be controlled to generate a third magnetic field in the first direction simultaneously as the lateral coils and the inner coils generate their fields.
US10780487B2 Bending and molding production line
A bending and molding production line includes an unwinding mechanism, a feeding and straightening device, a cutting-off mechanism, a bending and molding device and a material loading mechanism, wherein the bending and molding device includes a base, the base is provided with two transverse sliding bases, the base is provided with a transverse driving device driving the transverse sliding bases, the base is provided with a central clamping device between the two transverse sliding bases, the transverse sliding bases are provided with a longitudinal sliding base in a sliding manner and are provided with a longitudinal driving device driving the longitudinal sliding base to slide, the longitudinal sliding base is provided with a bending and molding device, the transverse sliding base at the left side is provided with a left clamping device, and the transverse sliding base at the right side is provided with a right clamping device.
US10780481B2 Bending and molding mechanism
A bending and molding mechanism includes two bases, wherein the bases are provided with a transverse sliding rail, two transverse sliding bases are disposed on the transverse sliding rail in a sliding manner, the base is provided with a transverse driving device driving the transverse sliding bases, the base is provided with a central clamping device, the transverse sliding bases are provided with a longitudinal sliding rail, the longitudinal sliding rail is provided with a longitudinal sliding base, the transverse sliding bases are provided with a longitudinal driving device driving the longitudinal sliding base to slide, the longitudinal sliding base is provided with a bending and molding device, one side of the transverse sliding base at the left side is provided with a left clamping device, and one side of the transverse sliding base at the right side is provided with a right clamping device.
US10780479B2 Method for straightening a distortion of a component by way of a straightening device, and straightening device
A method for straightening a distortion of a component by way of a straightening device is provided. The straightening device includes a clamping element for clamping in the component, a straightening element for introducing a straightening force into the component, and an anvil element for supporting the component during the introduction of the straightening force. Furthermore, a straightening device for straightening a distortion of a component is provided. The straightening device includes a clamping element for clamping in the component, a straightening element for introducing a straightening force into the component, an anvil element for supporting the component during the introduction of the straightening force, and a control element for operating the straightening device.
US10780474B2 Robust band tension control
A metal band is first rolled in a front and then in a rear (downstream) roll stand of a multi-stand rolling train. A looper between the roll stands may detect a band tension in the metal band. The band tension is supplied to a first and a second tension controller to determine an application additional target value and a speed additional target value. The second tension controller may only determine a value less than or greater than 0, as the speed additional target value, if the band tension is above or below an upper or lower band tension limit. Otherwise, the speed additional target value may be 0. The first tension controller is also supplied with a target tension that falls between the band tension limits. The application additional target value may be used to act on the rear roll stand.
US10780473B2 Cement solidification device for waste and method therefor, and zero-liquid discharge air pollution control system and method therefor
A cement solidification device for waste includes a slurrying vessel 14 that dissolves and slurries waste 11 containing harmful substances and deliquescent compounds in solvent water 12 to obtain slurried material 13; an iron-based additive supply unit 16 that adds an iron-based additive 15 to the slurrying vessel 14; a cement kneading vessel 20 that adds a cement solidifying agent 17 from a cement-solidifying agent supply unit 18 to the slurried material 13 in which the iron-based additive 15 is mixed to obtain a cement kneaded product 19; and a cement solidification unit 22 that cures the cement kneaded product 19 to form a cement solidified product 21.
US10780467B2 Methods and apparatus for surface wetting control
Methods and apparatus for surface wetting control are disclosed. In certain described examples, an apparatus can expel fluid from a droplet on a surface using a transducer mechanically coupled to the surface. A first area of the surface can have a first wettability for the fluid, and a second area of the surface can have a second wettability for the fluid. The first wettability of the first area of the surface can be greater than the second wettability of the second area of the surface. The first area and the second area can be arranged in a patterned arrangement.
US10780466B2 Method and device for biofouling prevention on vessels by means of UV radiation and surface modification
The invention provides an object (10), that during use is at least partly submerged in water, wherein the object (100) is selected from the group consisting of a vessel (1) and an infrastructural object (15), the object (10) further comprising an anti-biofouling system (200) comprising an UV emitting element (210), wherein the UV emitting element (210) is configured to irradiate with UV radiation (221) during an irradiation stage one or more of (i) a first part (111) of an external surface (11) of said object (10) and (ii) water adjacent to said first part (111) of said external surface (11) of said object (10), wherein the object (10) further comprises protruding elements (100) with the UV emitting element (210) configured between the protruding elements (100) and configured depressed relative to the protruding elements (100).
US10780465B2 Apparatus for cleaning a felt in a system for producing a paper web
An apparatus for cleaning a felt in a system for producing a paper web has a device for introducing a cleaning liquid into the felt and at least one following suction device in the direction of movement of the felt and having a vacuum duct, through which the cleaning liquid is suctioned out of the felt. The suction device between the vacuum duct and the felt is formed with suction ducts, through which the cleaning liquid in the felt is suctioned away. At least one of the suction ducts is assigned an inflatable valve element. In the inflated state of the valve element the suction duct is closed and in its ventilated state the suction duct is opened.
US10780462B2 Washing apparatus for cleaning game, fruit, vegetables, fish or crustacea in a container
An apparatus for cleaning game, fruit, vegetables, fish, or crustacea in a container has a pipe and a connector connected to the pipe adjacent one end of the pipe. The pipe has a plurality of apertures formed in spaced relation to each other along a length of the pipe. The pipe is adapted to extend generally vertical within the container. The plurality of apertures are adapted to direct a flow of water in a generally cyclonic path in the container. The connector is adapted to introduce water into and through the pipe from a water hose or a conduit. A fastener is affixed to the pipe or the connector so as to removably affix the pipe to the a container. A spacer is affixed to the pipe so as to position the pipe a distance away from a wall of the container.
US10780458B2 Ultrasound sensor and method of manufacturing thereof
An ultrasound sensor includes: a diaphragm; a plurality of first electrodes; a plurality of second electrodes; and a plurality of piezoelectric layers which is provided between the first electrode and the second electrode, in which, in a Z-direction, a portion in which the first electrode, the piezoelectric layer and the second electrode are overlapped is referred to as an active portion, and a range to the extent that the diaphragm is oscillatable by driving the active portion is referred to as a movable portion, when a unit including one movable portion and the active portion which is provided within the one movable portion is referred to as one ultrasound element in plan view, two or more types of ultrasound elements in which a dimension of the active portion with respect to a dimension of the movable portion is different from each other in plan view are provided.
US10780457B2 Vibration generator moving vibrator by magnetic field generated by coil and vibrator-mounted holder used in vibration-generator
A vibrator-mounted holder is attached to a casing of a vibration generator which moves a vibrator to generate a vibration when used. The vibrator-mounted holder includes a vibrator, a vibrator retention unit retaining the vibrator, a fixing unit fixed to a casing, and an arm. The vibrator includes a magnet having a plate shape parallel to a horizontal surface and a yoke arranged on the magnet. The arm connects the fixing unit to the vibrator retention unit, and supports the vibrator retention unit in a manner that the vibrator retention unit is displaceable with respect to the fixing unit. The yoke has a projecting portion which is projected downward and fixed to the vibrator retention unit. The arm is connected to a portion, at which the projecting portion is arranged, within the vibrator retention units.
US10780449B2 Spray accessory having filter for vehicle washer spray system
The disclosed inventive concept provides a fluid accessory for facilitating the dispensing of fluid onto a vehicle's windshield, cameras, sensors, or the like. The fluid accessory includes a body having an inlet portion and an outlet portion in which an inlet adapter and an outlet adapter, respectively, are fitted. The fluid accessory also includes a sleeve which is fitted within the body and around the inlet adapter. The body includes a plurality of longitudinal protrusions extending radially into the body. The sleeve and longitudinal projections cooperate to define a plurality of debris collection channels for collecting debris flowing within the fluid and through the fluid accessory. The fluid accessory also includes a filter media, such as a filter media, which is positioned between the outlet adapter and the body.
US10780446B2 Process for processing an adhesive and a device therefor
The invention relates to a process for processing an adhesive, wherein the process comprises applying an adhesive precursor product onto an adhesive carrier and activating and crosslinking the adhesive precursor product by treating the adhesive precursor product with water vapor and heat in a reaction chamber, and wherein the process is characterized in that air mixed with reaction gases forming during the activation and crosslinking in the reaction chamber is conducted away from the reaction chamber and recirculated as circulating air into the reaction chamber, wherein a portion of used air of the air recirculated as circulating air is replaced by fresh air. The invention further relates to a corresponding device for processing a pressure sensitive hot-melt adhesive.
US10780444B2 System and method for detection of cells
A system and method for detection of cells is disclosed. Target cells, such as circulating tumor cells (CTCs), may be of interest. Magnetic beads may be bound to the target cells. After which, the target cells (with the magnetic beads attached thereto) may be identified using an applied magnetic field. In one example, magnetic sensors may be used to detect movement of the target cells responsive to an applied magnetic field. In another example, an optical sensor (such as a camera) may be used to detect movement of the target cells responsive to an applied magnetic field. Further, separate from identification of the target cells, the target cells may be sorted using an applied magnetic field. In this way, a magnetic field may be used in either or both of target cell identification or target cell sorting in order to detect target cells of interest.
US10780442B2 Cannabis trichome separation using chilled water
Cannabis plant material is gently ground, mixed with chilled water and then agitated. The trichomes, being made brittle by the lowered temperature of the water, fall off the plant material during agitation. The mixture is then filtered in multiple stages to obtain the trichomes in different size fractions, which are collected separately and then dried.
US10780441B2 Production plus hammer tip
A hammer tip for releasable integration with a hammer, used in a size reducing machine. The hammer tip is separated into a production block with a top working edge and a spacer block. The production block and spacer block utilize a saddle back attachment to the hammer. The production block is further supported with a lock ledge integration to the spacer block. The production block with a single top working edge reduces maintenance cost, reduces downtime and improves machine throughput.
US10780439B2 Magnetic screwdriver device
A magnetic screwdriver device includes one pad without magnetism, one driving shaft, and one driven shaft. The two shafts, which have magnetic attraction between each other, are disposed on opposite sides of the pad respectively and attract to each other. The driving shaft is used to transmit torque to actuate the driven shaft rotation. When the torque out of predetermined value overcomes the friction force between the driven shaft and the pad, the driven shaft will be stop.
US10780437B2 Microfluidic system and method of controlling particles based on artificially structured acoustic field
Disclosed is a microfluidic system based on an artificially structured acoustic field, comprising a microcavity used to accommodate a solution containing particles and a ultrasonic emission device used to emit ultrasound, and further comprising a phononic crystal plate placed in the microcavity. The phononic crystal plate has an artificial cycle structure, and is used to modulate the acoustic field so as to control the particles. Also disclosed is a method of controlling microfluid particles based on an artificially structured acoustic field. In the particular embodiments, since a microcavity, an ultrasonic emission device and a phononic crystal plate are comprised, the ultrasonic emission device is used to emit ultrasound, and the phononic crystal plate has an artificial cycle structure, and is used to modulate the acoustic field so as to control the particles.
US10780436B2 Multi-channel microfluidic device and method for using the same
A multi-channel microfluidic device for multi-parallel analyte detection includes a substrate and a multi-channel microfluidic assembly formed in the substrate. The multi-channel microfluidic assembly comprises a synchronized port; a plurality of separate ports; a plurality of channels arranged in parallel, where each of the plurality of channels includes a first end and a second end opposite to the first end; a first branch channel assembly; and a plurality of second branch assemblies. The synchronized port is connected with all the first ends of the plurality of the channels via the first branch channel assembly. Each of the plurality of the separate ports is in connection with the second end of each of the plurality of the channels via each of the plurality of the second branch channel assemblies.
US10780435B2 Fluidic devices with at least one actionnable fiber
Disclosed is a minifluidic device including a matrix, an elongated guiding duct embedded at least in part in the matrix, with at least one port to the outside of the matrix, a movable fiber at least partly contained in the guiding duct, and able to undergo within the guiding duct, and at least along some part of the fiber, at least one action selected among a sliding, or a deformation, or a rotation and at least one of the movable fiber or the guiding duct is elastic or is non linear along at least part of its length, or at least part of the matrix is elastic.
US10780430B2 Sequential impregnation for noble metal alloy formation
Methods are provided for forming noble metal catalysts comprising both platinum and a second Group VIII metal, such as palladium, with improved aromatic saturation activity. Instead of impregnating a catalyst with both platinum and another Group VIII metal at the same time, a sequential impregnation can be used, with the Group VIII metal being impregnated prior to platinum. It has been discovered that by forming a Group VIII metal-impregnated catalyst first, and then impregnating with platinum, the distribution of platinum throughout the catalyst can be improved. The improved distribution of platinum can result in a catalyst with enhanced aromatic saturation activity relative to a catalyst with a similar composition formed by simultaneous impregnation.
US10780428B2 Method for producing mechanically stable catalysts for hydrogenating carbonyl compounds, said catalysts and hydrogenating method
A process for producing a metal carbonate-containing shaped catalyst body for the hydrogenation of an organic compound having one or more carbonyl group, in which a) a metal carbonate composition which contains, based on the total weight of the metal carbonate composition, from 70 to 94.5% by weight of a metal carbonate mixture containing two or more than two metal carbonates of two or more than two different metals (M), from 5 to 25% by weight of metallic copper, and from 0.5 to 5% by weight of tableting aid is provided, b) a shaped body is formed from the metal carbonate composition provided in step a), and c) the shaped body obtained in step b) is activated in the presence of hydrogen at a temperature in the range from 150 to 250° C.
US10780423B2 Powder for catalysts and catalyst for exhaust gas purification
A catalyst powder according to the present invention is a catalyst powder that includes: a core portion that contains ceria and zirconia; and a surface layer portion that is located on the core portion and contains ceria and zirconia. The ratio (M2/M1) is 0.30 or more and 0.95 or less, the ratio (M2/M1) being the ratio of a mole fraction M2 (mol %) of cerium in the surface layer portion measured using X-ray photoelectron spectroscopy to a mole fraction M1 (mol %) of cerium in the entire powder. It is preferable that the ratio (M4/2/M3/1) between M3/1 and M4/2 is 1.1 or more and 5.0 or less, wherein M3/1 (=M3/M1) represents the ratio between a mole fraction M3 (mol %) of zirconium in the entire powder and a mole fraction M1 (mol %) of cerium in the entirety of the powder, and M4/2 (=M4/M2) represents the ratio between a mole fraction M4 (mol %) of zirconium measured using X-ray photoelectron spectroscopy and a mole fraction M2 (mol %) of cerium measured using X-ray photoelectron spectroscopy.
US10780418B2 Zero-valent iron pillared montmorillonite repair material, and preparation method therefor and application thereof
A zero-valent iron pillared montmorillonite repair material relates to the field of environmental functional materials. A preparation method thereof is mainly to obtain the zero-valent iron pillared montmorillonite repair material by reducing hydroxyl-iron pillared montmorillonite at high temperature in a mixed atmosphere of hydrogen and nitrogen, and mainly includes: (1) preparation of Na-montmorillonite; (2) preparation of a polyhydroxy-iron pillared solution; (3) preparation of hydroxy-iron pillared montmorillonite; and (4) obtaining the zero-valent iron pillared montmorillonite repair material by means of high-temperature reduction-calcination in the mixed atmosphere of hydrogen and nitrogen. The zero-valent iron pillared montmorillonite repair material can be used for removing degradation-resistant organic pollutants, and degrading organics into small molecular organics by means of peroxymonosulfate (PMS).
US10780416B2 Polymeric sorbents for aldehydes
Polymeric sorbents for aldehydes including formaldehyde are provided. More particularly, the polymeric sorbents are a reaction product of a divinylbenzene/maleic anhydride precursor polymeric material with a nitrogen-containing compound. The nitrogen-containing compound is covalently attached to the resulting polymeric sorbent. Additionally, methods of sorbing aldehydes (i.e., aldehydes that are volatile under use conditions) on the polymeric sorbents and compositions resulting from the sorption of aldehydes on the polymeric sorbents are provided. The polymeric sorbents typically are porous with the pores often being in the size range of mesopores and/or micropores.
US10780413B2 High-speed on demand microfluidic droplet generation and manipulation
Methods and devices for the formation and/or merging of droplets in microfluidic systems are provided. In certain embodiments a microfluidic droplet merger component is provided that comprises a central channel comprising a plurality of elements disposed and spaced to create a plurality of lateral passages that drain a carrier fluid out of a fluid stream comprising droplets of a first fluid contained in the carrier fluid; and a deformable lateral membrane valve disposed to control the width of said center channel.
US10780411B2 Multi-channel direct-deposit assembly method to high-throughput synthesize three-dimensional macroporous/mesoporous material array
A multi-channel direct-deposit assembly method is disclosed to high-throughput synthesize three-dimensional macroporous/mesoporous (3DMM) material array with precisely controlled composition, pore size, and pore structure. The macropore size of the synthesized 3DMM material is in the range of 50-1000 nm; the mesopore size of the synthesized 3DMM material is in the range of 1-50 nm. The surface area of the 3DMM material is in the range of 20-1000 m2/g. The 3DMM material array can be used for rapid synthesis, screening and manufacture of catalysts and nanosensors.
US10780408B2 Mixing apparatus and single-use apparatus for a mixing apparatus
A mixing apparatus for mixing substances includes a single-use apparatus and a reusable apparatus. The single-use apparatus includes a flexible mixing tank configured to receive the at least two substances to be mixed, is plastic, and has a rotor arranged in the mixing tank. The rotor includes an impeller configured to mix the at least two substances, the impeller being magnetically contactlessly drivable and free of coils and permanent magnets. The reusable apparatus includes a support tank configured to receive the mixing tank and a stator configured to magnetically contactlessly drive the rotor about an axis of rotation in an operating state. The stator includes at least one permanent magnet configured to generate a permanent magnet flux and at least one winding configured to generate an electromagnetic flux, the permanent magnet flux and the electromagnetic flux together being capable of driving the rotor.
US10780403B2 Composite separation membrane
A composite separation membrane is disclosed prepared by forming a separation layer on a surface of a porous support membrane, characterized in that the porous support membrane contains 50% by mass or more of polyphenylene ether; that the separation layer is constituted from a first separation layer and a second separation layer; that the first separation layer is formed with a thickness of from 50 nm to 1 μm on the surface of the porous support membrane and is a sulfonated polyarylene ether copolymer which comprises a repeated structure of a specific hydrophobic segment and a specific hydrophilic segment; and that the second separation layer is formed with a thickness of from 1 nm to less than 50 nm on a surface of the first separation layer and is an alternately-layered product constituted from one or more kinds of ionomers.
US10780396B2 Methods for the treatment of a flue gas stream using catalytically-enhanced sorbent compositions
A sorbent composition that is useful for injection into a flue gas stream of a coal burning furnace to efficiently remove mercury from the flue gas stream. The sorbent composition may include a sorbent with an associated ancillary catalyst component that is a catalytic metal, a precursor to a catalytic metal, a catalytic metal compound or a precursor to a catalytic metal compound. Alternatively, a catalytic metal or metal compound, or their precursors, may be admixed with the coal feedstock prior to or during combustion in the furnace, or may be independently injected into a flue gas stream. A catalytic promoter may also be used to enhance the performance of the catalytic metal or metal compound.
US10780392B2 Multi-stage membrane for N2 rejection
Nitrogen is removed from biogas using a three-stage separation system based on gas separation membranes. The first stage separates a biomethane feed stream into a first permeate gas stream and a first retentate gas stream. The second stage separates the first permeate stream into a biomethane product gas and a first low quality biomethane gas stream. The third stage separates the first retentate into a second low quality biomethane gas stream and a waste gas. A biogas feed stream is pretreated to remove amounts of water, VOCs, and CO2 to yield a methane-enriched biogas stream. The methane-enriched biogas stream is compressed together with the first and second low quality biomethane gas streams to form the biomethane feed stream.
US10780390B2 Gas-phase oxidation/decomposition and absorption integrated device and application thereof
Provided are a gas phase oxidation/decomposition and absorption integrated device and application thereof in a gas-liquid system. The device comprises a housing (100), a motor (102), and a boost regulator (103); the housing (100) is internally provided with a rotating chamber (120) and a discharge chamber (122); the rotating chamber (120) comprises a rotating shaft (119), a turntable (124), a liquid distributor (123), packing layers (110), a guiding round table (111), a liquid inlet (108), a liquid outlet (112), and a first gas outlet (109); the discharge chamber (122) is located under the rotating chamber (120) and comprises a discharge chamber housing (121) and a plasma generator.
US10780388B2 Metal-organic frameworks appended with cyclic diamines for carbon dioxide capture
Achieving the selective and reversible adsorption of CO2 from humid, low partial pressures streams such as the flue gas resulting from the combustion of natural gas in combined cycle power plants (4% CO2) is challenging due to the need for high thermal, oxidative, and hydrolytic stability as well as moderate regeneration conditions to reduce the energy of adsorption/desorption cycling. Appending cyclic primary, secondary diamines, exemplified by 2-(aminomethyl)piperidine (2-ampd), to the metal-organic frameworks Mg2(dobpdc) (dobpdc4−=4,4-dioxidobiphenyl-3,3-dicarboxylate), Mg2(dotpdc) (dotpdc4−=4,4″-dioxido-[1,1′:4′,1″-terphenyl]-3,3″-dicarboxylate) or Mg2(pc-dobpdc) (pc-dobpdc4−=dioxidobiphenyl-4,4′-dicarboxylate) produces adsorbents of the classes EMM-44, EMM-45, and EMM-46, respectively, that display step-shaped adsorption of CO2 at the partial pressures required for 90% capture from natural gas flue gas at temperatures up to or exceeding 60° C. Using a cyclic diamine in place of a diamine functionalized with bulky alkyl groups enables fast adsorption/desorption kinetics with sharp CO2 adsorption and desorption steps.
US10780387B1 System and method for gas quality and efficiency of a pressure swing adsorption gas separation unit
The invention provides a system and method that applies novel algorithms and compositions for efficiently adjusting compression, unit turn down, pressure and flows of a pressure swing adsorption unit. The present invention also reduces overall horsepower, increases unit's product gas recovery, maximizes product gas quality and allows for non-disturbance of upstream and downstream equipment in regard to pressure and flow oscillations. Raw gas streams addressed include methane (CH4), nitrogen (N2), oxygen (O2), carbon dioxide (CO2), water (H2O), Hydrogen Sulfide (H2S) and non-methane organic compounds (NMOC) gases/vapors. The invention incorporates a CO2 and H2O trim units and provides a VPSA N2 and O2 rejection section.
US10780383B2 Supply air arrangement for a mobile device
A supply air arrangement for a mobile device includes: at least one inlet; at least one air duct; at least one outlet; and a filtering arrangement comprising at least two filtering elements. A first filtering element and a second filtering element that is formed separately from the first filtering element are arranged in the air duct.
US10780380B1 Well production stream solid debris separator apparatus
A well production stream solid debris separator apparatus. The apparatus includes a spherical vessel. A cylindrical sump extends below and radially from the spherical vessel. A centrifugal cylinder is positioned within the spherical vessel, the centrifugal cylinder having an axis concentric with a diameter of the spherical vessel and having an open bottom. An outlet port passes through the cylindrical vessel and through the spherical vessel with the outlet port opposed to the cylindrical sump. An inlet port passes through the spherical vessel and passes into the centrifugal cylinder substantially tangential to an inner surface of the centrifugal cylinder.
US10780378B2 Process for filtration of fluids and filter apparatus for performing the process
The invention relates to a process for filtration of fluids, especially of aqueous media, by means of a backflush filter apparatus consisting of a cylindrical housing, a cylindrical and perforated support body installed coaxially therein, a filter material, a support fabric, and a mobile backflush device present therein, said process enabling improved removal of fine and ultrafine particles, and of particles with greasy or compressible consistency, and allowing higher solid concentrations. The process according to the invention has the steps below. a) Formation of a filtercake in the perforation of the support body; b) deposition of the relatively fine particles or of the particles with greasy or compressible consistency on or in the filtercake; c) backflushing after attainment of the predefined filter loading or of the maximum permissible pressure differential, or when the filtrate volume flow goes below a minimum. A further aspect of the invention is a filter apparatus for performance of the process, characterized in that the filter material consists of a filter fabric with an air permeability of 700-1300 l/m2s at pressure differential 200 Pa.
US10780375B2 Liquid filtration apparatus
A liquid filtration apparatus includes a series of upright filter plates forming a filter plate pack. Filtering spaces are formed in the filter plate pack. The liquid filtration apparatus includes at least one filtering space and a filter chamber that is at least partly limited laterally by a filter media. The at least one filtering space has an elongated bottom discharge opening at a level below the filter chamber. The elongated bottom discharge opening is provided with a first openable and closable hatch arrangement and with a second openable and closable hatch arrangement extending across the elongated bottom discharge opening.
US10780374B2 Animal byproduct recovery system
A system for recovery of animal byproducts and providing water reuse from an animal processing plant waste stream. In one embodiment of the invention there is an equalization tank forming part of an animal processing plant that is mechanically filtered to recover animal byproducts from a water mixture in the equalization tank. In another aspect of the invention there is a skimmer tank that contains a skimmer mixture with water and animal byproducts. The system mechanically separates the animal byproducts from the skimmer mixture in a manner that is suitable for human consumption. The system also allows the separated water to be reused in the animal processing plant.
US10780365B2 Bubble generating apparatus
An apparatus for generating bubbles. The apparatus may include a wheel having an outer surface that lies on a reference cylinder. The wheel may be configured to rotate about a first rotational axis. A fan device that is configured to generate an air stream may be located within the reference cylinder. A bubble generating assembly may also be located within the reference cylinder. The bubble generating assembly may include at least one bubble generating device. In use, rotation of the wheel about the first rotational axis may be configured to load a bubble solution onto the bubble generating device of the bubble generating assembly. In addition, or as an alternative, rotation of the wheel about the first rotational axis may be configured to rotate the fan device about a second rotational axis to generate the air stream.
US10780363B2 Kite line reeling device
This invention concerns a line reeling device for reeling front and back lines of a kite. The device includes a reeling mechanism comprising a first reel and a second reel which are located in an enclosure and on which the front and back lines are, in use, wound respectively. The reels are arranged so that their rotation in one direction retracts the lines and their rotation in the other direction deploys the lines. The reeling mechanism further includes reel connecting means which is operable to cause the reels to rotate in harmony in one configuration and rotate independently in another configuration. The reeling mechanism also has a braking mechanism for controlling rotation of the reels and a control mechanism which is in connection with the braking mechanism. The control mechanism is operable between a first, locked position wherein rotation of the reels is obstructed and a second, released position wherein rotation of the reels is allowed.
US10780362B2 Method and an apparatus to improve the realism of a model locomotive motion and sounds
A method and an apparatus that improves the motion and sounds of a model locomotive such that they more closely represent or simulate that of a real locomotive. The motion and sounds are changed in such a way that it is more realistic when compared to a real locomotive that is pulling a heavy load.
US10780359B2 Systems and methods for a connected augmented environment
Systems and methods presented herein include an amusement park system that includes an augmented experience system. The augmented experience system is configured to track guest interactions of a plurality of guests of an amusement park with one or more employees of the amusement park, one or more mobile devices, one or more wearable devices, one or more themed devices, or one or more physical objects disposed within a real-world environment of the amusement park. The augmented experience system is also configured to augment the real-world environment of the amusement park based at least in part on data relating to the guest interactions.
US10780353B2 Methods and systems for processing gaming data
Methods and systems for content processing are described. In one embodiment, gaming data is received from a gaming source server. The gaming data associated with a game. A content signal is received from a signal source during presentation of programming content. The programming content is associated with the content signal and the game. A determination of whether the content signal includes the trigger is made. The device content is presented using the gaming data. The device content is in synchronization with the presentation of the programming content based on a determination that the content signal includes a trigger. Additional methods and systems are disclosed.
US10780350B2 Spatially and user aware second screen projection from a companion robot or device
A robot, including: a controller that communicates with a computing device, wherein the computing device executes a video game and renders a primary video feed of the video game to a display device, the primary video feed providing a first view into a virtual space that is defined by the executing video game; a camera that captures images of a local environment in which the robot is disposed; a projector; wherein the controller processes the images of the local environment to identify a projection surface in the local environment; wherein the computing device generates a secondary video feed of the video game and transmits the secondary video feed of the video game to the robot, the secondary video feed providing a second view into the virtual space; wherein the controller of the robot activates the projector to project the secondary video feed onto the projection surface in the local environment.
US10780349B2 Virtual reality collision interpretation
A rhythm-based video game (“game”) is disclosed. In the game, a player slashes blocks representing musical beats using a pair of energy blades resembling a lightsaber. A gaming console renders multiple digital objects, e.g., digital blocks, digital mines and digital obstacles, that are approaching a player in a virtual space. The gaming console also renders a digital representation of an instrument, e.g., a lightsaber (“digital saber”), using which the player slashes, cuts or otherwise interacts with the digital blocks to cause a digital collision between the digital saber and the digital blocks. The player can score by slashing the digital blocks, not hitting the digital mines and avoiding the digital obstacles. The game presents the player with a stream of approaching digital objects in synchronization with music, e.g., a song's beats, being played in the game. The pace at which the digital blocks approach the player increases with the beats.
US10780345B2 Video game processing apparatus and video game processing program product
A video game processing apparatus is provided for controlling progress of a video game while displaying a player character on a display screen of a display device provided with a touch panel. The video game processing apparatus is provided with a virtual controller information memory for storing virtual controller information on a virtual controller. The display device is caused to display the virtual controller on the display screen on the basis of the virtual controller information. In a case where an operational input to the virtual controller displayed on the display screen is received, the video game processing apparatus updates a shape of the virtual controller on the basis of the virtual controller information, and controls an action of the player character on the basis of the received operational input. The operational input may include a slide operation and a tap operation, for example.
US10780338B1 System and methods for designing and manufacturing bespoke protective sports equipment
A bespoke protective sports equipment to be worn by a player engaged in a sporting activity is provided. The bespoke sports equipment system includes methods for acquiring, storing and processing a player's unique data, namely the anatomical features of the body part against which the bespoke equipment is worn. The systems also includes methods of using the player's unique data to manufacture the bespoke protective equipment with a custom formed internal padding assembly that substantially corresponds to the player's unique data. The system and method allows for the design and manufacture of bespoke protective sports equipment that is purposely designed and manufactured to match the anatomical specifications of the player's body part.
US10780336B2 Systems and methods for electronic targeting or hit/touch detection
The present invention provides systems and methods for electronic targeting, and hit or touch detection of projectiles or objects, such as from some type of gun, bow (archery), ball, human touch, animal touch. Targets/nodes have hit/touch/contact detection implements and are in radio communication with a gateway, which may be standalone or integrated into a master target. The gateway is in radio communication with an app on a smart device and also includes the capability for data connectivity to the cloud. Electronic gaming and other touch event activities remote activities of geographically disparate groups of targeting-type or hit/touch/contact detection implements are provided.
US10780329B2 Multi-component golf club wedge
An iron-type golf club head assembly kit including a club head main body, a first sole component, and a second sole component interchangeably associable with the main body. When the first sole component is associated with the main body, the main body and the first sole component form a first club head comprising a sole surface having a first parting line, formed between the first sole component and the main body, and a first sole contour. When the second sole component is associated with the main body, the main body and the second sole component form a second club head comprising a second sole surface having a second parting line, formed between the second sole component and the main body, and a second sole contour that differs from the first sole contour.
US10780321B2 Head and neck floating support device
A water floating device that offers support for the head or neck of a user when swimming or practicing water exercises. The floating support device includes a unitary piece body made of a floating and waterproof material. The unitary piece body has a U-shape including a curved central section having a first leg on a first end and a second leg on a second end. The first leg and the second leg project from the curved central section. The first leg and the second leg angle inwardly to one another.
US10780320B2 Intelligent treadmill and method for controlling the same
An intelligent treadmill includes a treadmill body and an intelligent speed control system. The treadmill body includes a treadmill deck and a motor. The treadmill deck includes an acceleration section, a holding section, and a deceleration section. The intelligent speed control system includes a gravity-center sensing device, a processor module, a motor driver, and a host computer. The gravity-center sensing device includes a plurality of infrared array sensors. The gravity-center sensing device is sequentially connected with the processor module, the motor driver and the host computer. The motor driver is connected with the motor. A method for controlling the intelligent treadmill includes the steps of: step 1: allowing a user to set upper and lower limit values of the position of the holding section; step 2: allowing the user to set a speed adjustment ratio value; step 3: acquiring the position of the center of gravity of a human body; step 4: detecting whether the center of gravity of the human body is within the holding section; step 5: detecting whether the center of gravity of the human body is within the acceleration section; step 6: the processor module detecting whether the center of gravity of the human body is within the deceleration section. It is convenient for the user to quickly and intelligently control the speed of the treadmill. The user can feel more safe and stable during exercise.
US10780317B1 Exercise apparatus
The present invention discloses a push-up exercise apparatus for performing push-up, particularly in close triceps position. The push-up exercise apparatus comprising a base member, a pair of spaced apart first support members centrally disposed on the base member at an angle of at least forty-five degrees, a pair of spaced apart second support members centrally disposed on the base member at an angle of at least forty-five degrees and parallel to the pair of first support members, a first handle disposed above the pair of spaced apart first support members and a second handle disposed above the pair of spaced apart second support members. The apparatus further enables to adapt a healthy lifestyle, aids in eliminating flabby arms and weak pectoral muscles and sculpts pectoral and triceps muscle.
US10780315B2 Body-building device and fitness method
A body-building device including a base body, a swing mechanism and a supporter is provided. The base body is used to support the whole body-building device. The swing mechanism is installed on the base body to enable 360-degree rotation in the circumferential direction or swing to any angle off the central axis of the base body. The supporter is installed at an upper end of the swing mechanism and makes direct contact with human body. With force applied by human body, it drives the swing mechanism to rotate or swing, while the swing mechanism generates a corresponding reset force during swing, thus enabling body building. Fitness methods are also provided.
US10780310B2 Leg press exercise machine
A leg press exercise machine, including: a main frame with first and second rotating bars connected thereto; a support assembly connected to each of the first and second rotating bars, wherein rotation of the first and second rotating bars causes the support assembly to move with respect to the main frame; a seat support bar; and a seat mounted onto the seat support bar, wherein the support assembly holds the seat support bar at a downward angle and wherein the rotating bars are disposed at an angle from 0 to 30 or about 20 degrees to the vertical when the machine is in its rest position.
US10780303B2 Automatic fire sprinklers, systems and methods for suppression fire protection of high hazard commodities including commodities stored in rack arrangements beneath ceilings of up to fifty-five feet in height
System and methods to provide ceiling-only suppression fire protection of up to fifty feet (50 ft.) of rack storage of cartoned unexpanded plastic commodities and less hazardous commodities, such as for example, Class 1, Class 2, Class 3, Class 4 and/or combinations thereof beneath a ceiling having a maximum ceiling height up to fifty-five feet (55 ft.). The systems and methods provide for hydraulic and system parameters that include a hydraulic design area based upon five to no more than twelve hydraulically most remote sprinklers spaced at a preferred sprinkler-to-sprinkler spacing of eight to ten feet (8-10 ft.) coupled to two to four branch lines tied to a common cross main supply pipe of firefighting fluid.
US10780299B2 Skincare system
A system and method may allow a person to rotate a skin care product based on the current climate to help skin transition to and react to changes in temperature and humidity the air. For example, each moisturizer may be formulated to support skin needs for a specific climate, such as tropical climate (i.e., humid and hot air), a desert climate (i.e., dry and hot air), a temperate climate (i.e., normal and mild air), and/or a polar climate (i.e., cold and dry air).
US10780295B2 Method for treating multiple sclerosis
Methods and devices for suppressing clinical symptoms of multiple sclerosis (MS) by irradiating a subject exhibiting the symptoms with an effective dose of UV-containing light from a light source and detecting a suppression of the clinical symptoms of MS. In particular, the detected suppression of the clinical symptoms is disassociated from the vitamin D production within the subject.
US10780290B2 Encased magnetic bone growth stimulating devices and methods of use
Encased magnetic bone growth stimulating devices and methods of use are provided herein. An example device includes a magnet and a biocompatible means for enclosing the magnet. The biocompatible means for enclosing the magnet further comprises a means for releasably coupling with the medical implant and a means for coupling the enclosing means to an implantable medical device.
US10780289B2 Waveform energy influence of objects using feedback control
A control system for delivering energy waveform radiation to influence in vivo tissue is described. For the system, the energy waveform radiation is generated by a radiation unit and is directed along a pathway to the tissue and a registration unit is provided to identify a start place relative to the in vivo tissue. Also, a monitor is provided to compare the start place with a base reference to measure an error signal between the start place and base reference. With this measured error signal, a controller operates the radiation unit using input from the monitor to effectively attain and maintain a zero error signal. More specifically, the controller can provide operational parameter inputs to the radiation unit for configuring the waveform radiation including a radiation frequency, f, and a volume intensity level, v, for the radiation and an exposure time interval, ti.
US10780288B2 Systems amd methods for suppressing and treating atrial fibrillation and atrial tachycardia
Disclosed herein are implantable medical devices and systems, and methods for used therewith, that selectively perform atrial overdrive pacing while an intrinsic atrial rate of a patient is within a specified range. Such a method can involve measuring intervals between a plurality of intrinsic atrial depolarizations that occur during a specified period, and classifying intrinsic atrial activity as stable or unstable based on the measured intervals. In response to classifying the intrinsic atrial activity as stable, atrial overdrive pacing is performed. In response to classifying the intrinsic atrial rate as unstable, atrial overdrive pacing is not performed (i.e., is abstained from being performed). Over time, effectiveness of performing atrial overdrive pacing using various different atrial interval shorting deltas are recorded in a log and updated, and the log is used to determine a preferred rate at which to perform atrial overdrive pacing for various different measured intervals.
US10780283B2 Systems and methods for analyzing electrical stimulation and selecting or manipulating volumes of activation
A system for identifying potential portions of a body in which electrical stimulation to treat a condition or disorder affects at least one symptom of the condition or disorder, stimulation effect, or side effect performs the following acts: obtaining, for each of multiple stimulation instances, an estimation of a region of the body stimulated during the stimulation instance and a score for each of at least one symptom, stimulation effect, or stimulation side effect; and determining, for each of multiple portions of the body using the scores and the estimates in a permutation test, a likelihood that stimulation of that portion of the body affects at least one symptom, stimulation effect, or stimulation side effect. In other embodiments, the system sets up a relationship between the outcomes of stimulation and influence of a particular part of the body on the outcome, and derives this influence using a pseudoinverse.
US10780282B2 Systems and methods for steering electrical stimulation of patient tissue and determining stimulation parameters
A method for determining a set of stimulation parameters for an electrical stimulation lead or steering electrical stimulation includes receiving a target geometrical parameter describing a stimulation field; receiving a first programming state; determining a first stimulation parameter for the first programming state that achieves the target geometrical parameter within at least 10% of the target geometrical parameter; and outputting set of stimulation parameters to be received by an electrical stimulation device for delivery of electrical stimulation to a patient via an electrical stimulation lead, wherein the set of stimulation parameters comprises the first stimulation parameter and represents the first programming state. In other embodiments, the target geometrical parameter is determined from either i) a first set of stimulation parameters or ii) a starting programming state and starting first stimulation parameter.
US10780278B2 Integrated multi-device cardiac resynchronization therapy using P-wave to pace timing
Methods, systems and devices for providing cardiac resynchronization therapy (CRT) to a patient using a leadless cardiac pacemaker (LCP) and an extracardiac device (ED). The LCP is configured to deliver pacing therapy at a pacing interval. Illustratively, the ED may be configured to analyze the cardiac cycle including a portion preceding the pacing therapy delivery for one or several cardiac cycles, and determine whether an interval from the P-wave to the pace therapy in the cardiac cycle(s) is in a desired range. In an example, if the P-wave to pace interval is outside the desired range, the ED communicates to the LCP to adjust the pacing interval.
US10780276B1 Systems and methods for selecting low-power, effective signal delivery parameters for an implanted pulse generator
Systems and methods for selecting low-power, effective signal delivery parameters for an implanted pulse generator are disclosed. A representative system includes a signal generator and a computer-readable medium that, for first and second signals, increases and decreases an amplitude of the signal over multiple steps from a baseline amplitude at which the patient has a baseline response. At individual step increases and decreases, the system receives a pain score based on the patient's response. The instructions compare the pain scores for the two signals and determine one of the signals for additional therapy to the patient, based on the pain scores and an expected energy consumption of the signals.
US10780273B2 Stimulation devices and methods for treating dry eye
Described herein are devices and methods of use thereof for treating dry eye, tired eye, or other forms of ocular discomfort such as from contact lenses. The methods generally include applying spatially and/or temporally patterned stimulation to one or more anatomical structures located in an ocular or nasal region. The electrical stimulation may elicit a reflex that activates the lacrimal gland or may directly activate the lacrimal gland or nerves innervating the lacrimal gland to produce tears. The devices may be implantable or handheld, and may be configured to deliver the spatially and/or temporally patterned stimulation patterns described.
US10780269B2 Apparatus and method for relieving pain using transcutaneous electrical nerve stimulation
Apparatus for transcutaneous electrical nerve stimulation in humans, the apparatus comprising: a housing; stimulation means mounted within the housing for electrically stimulating nerves; an electrode array releasably mounted to the housing and connectable to the stimulation means, the electrode array comprising a plurality of electrodes for electrical stimulation of nerves; control means mounted to the housing and electrically connected to the stimulation means for controlling at least one characteristic of the stimulation means; monitoring means mounted to the housing and electrically connected to the stimulation means for monitoring at least one characteristic of the stimulation means; user interface means mounted to the housing and electrically connected to the control means for controlling the stimulation means; display means mounted to the housing and electrically connected to the control means and the monitoring means for displaying the status of the stimulations means; and a strap attached to the housing; wherein the strap is configured to hold the housing, stimulation means and electrode array at a specific anatomical location to treat pain.
US10780268B2 Transcranial stimulation device and method based on electrophysiological testing
The present method and system provides for the clinical application of neurostimulation and/or neuromodulation to a patient. The method and system includes receipt and acquisition of patient data, processing of that data relative to one or more known data sets, and determination of a good-fit trigger specific treatment protocol. The method and system provides for application of the protocol to the patient, including delivery of neuromodulation and biofeedback. Based thereon, the method and system re-iterates the goodness of fit determination for further treatment to the patient.
US10780263B2 Implantable electric stimulation system and methods of making and using
A lead assembly includes a lead with a distal end and a proximal end. The lead includes a plurality of electrodes disposed at the distal end and a plurality of terminals disposed at the proximal end. The lead also defines at least one central lumen and a plurality of outer lumens. The central and outer lumens extend from the proximal end to the distal end such that the plurality of outer lumens extend laterally from the at least one central lumen. The lead further includes a plurality of conductive wires. Each conductive wire couples at least one of the plurality of electrodes electrically to at least one of the plurality of terminals. At least two conductive wires are disposed in each of the plurality of outer lumens.
US10780262B2 Method of assembling an electrode array that includes a plastically deformable carrier
A method of assembling an implantable electrode array from a coupon (108) formed from plastically deformable material. Layers of material are disposed on the coupon to form the electrodes (48) and conductors (62) of one or more electrode arrays. Sections of the coupon on which the electrodes and conductors are removed, along with the electrodes and conductors to form the electrode arrays. The removed sections of the coupon thus function as plastically deformable carriers (74) for the arrays (40).
US10780261B2 Pacing output K-factor improvements
In an example, an implantable medical device (IMD) includes a hold capacitor configured to deliver an electrical therapy pulse, and charge pump circuitry configured to transfer energy from the battery to the hold capacitor. In this example, the charge pump circuitry comprises a plurality of capacitors, and switching circuitry configured to put the charge pump circuitry into a K-factor mode selected from a group of K-factor modes by opening and closing a combination of switches connected to the plurality of capacitors.
US10780259B2 Tamper evident closure assembly
A tamper evident closure assembly is for use with a fitting having an outer sidewall with internally-directed threads, externally-directed splines, and an open post. The closure assembly includes a cap, a collar, and a frangible attachment coupling the cap and collar. The cap, collar, and frangible attachment are formed integrally as an integral unit. A radial lug on the cap engages with the fitting threads. A pawl on the collar allows rotation of the integral unit on the fitting in a first rotational direction and prevents rotation in a second rotational direction. Application of the integral unit to the fitting engages the radial lug with the threads on the fitting and the post and the cap form a fluid seal. Tampering with the integral unit when the integral unit is applied to the fitting severs the frangible attachment, thereby defining the cap and collar as separate pieces.
US10780258B2 Thermic infusion system
A thermic infusion system includes a thermal tubing system and a control system. The thermal tubing system has a tubal body with at least one tubal segment. The tubal segment includes a thermal element that may receive energy, such as electrical energy, to increase temperature within the tubal body. The control system may regulate the amount of energy received by the tubal segment using one or more sensors positioned within the tubal body.
US10780257B2 Assemblies for identifying a power injectable access port
A method of treating a patient using a power-injectable access port, including implanting the power-injectable access port in the patient, imaging the power-injectable access port following implanting, and power injecting a fluid into the patient through the power-injectable access port. The power-injectable access port includes a septum covering a reservoir, the septum including a radiopaque material forming at least one letter, the at least one letter indicating that the power-injectable access port is suitable for power injection. The power-injectable access port is designed to accommodate a pressure developed within the reservoir of at least 35 psi, and a fluid flow rate of at least 1 milliliter per second. Imaging the power-injectable access port produces an image, and the method includes identifying the at least one letter on the image to confirm that the power-injectable access port is suitable for power injecting a fluid.
US10780253B2 Method for producing a balloon for angioplasty
A method for producing a balloon from a suitable blank is provided. The blank is introduced into an outer mold heated an first expanded to expand it against the inner wall of the outer mold. Pressure is reduced to relax the blank away from the inner wall. The three-dimensional volume of the mold is changed. Second expanding of the blank expands again against the inner wall of the changed volume of the outer mold. Balloons of the invention consist of a middle cylindrical region and two end regions delimiting the middle cylindrical region. With a pressure application of 6 bar, a ratio of the cross section in the middle region to the cross section in the end region is at least 2, and preferably greater than 3.
US10780252B2 Catheter with inflatable balloon
A balloon catheter assembly is provided with an outer catheter, an inner catheter, an outer adapter and a balloon, and is configured such that the balloon resides entirely within a predetermined volume having an outer diameter substantially equal to or less than the outside diameter of the distal end of the outer catheter when the balloon is in a deflated configuration. Methods of using and steering the catheter assemblies are also provided.
US10780250B1 System and method for selective pressure-controlled therapeutic delivery
A treatment system includes a guide sheath, and a catheter provided with a pressure-controlled element. The pressure-control element preferably includes an expanded configuration adapted to extend across a small feeder vessel branching from the splenic vein. The pressure-control element is positioned with the feeder vessel, and a therapeutic agent is delivered under pressure directly into the feeder vessel, where it is forced to penetrate deep into tissue. Pressure responsive elements for monitoring intravascular pressure are also provided to time delivery of the therapeutic agent for maximum uptake by the target organ.
US10780249B2 Needle capture safety interlock for catheter
Catheter assembly (10) comprises catheter (22), needle (12) having sharp distal tip disposed in catheter (22), catheter hub (14) housing catheter (22) and needle (12), catheter hub (14) having collar (34) including notch (36), needle shield (20) connected to catheter hub (14) when needle (12) is in first position, and clip (40) disposed in needle shield (20) that cooperates with needle (12), wherein clip (40) engages catheter hub (14) in first position of needle (12), and clip (40) disengages catheter hub (14) via notch (36) when needle (12) is retracted to second position to enclose at least portion of needle (12). Clip (40) is mounted in outer housing (38) of needle shield (20) via spade (66) having outer wall (70) exposed to outside of needle shield (20), in order to reduce overall width of needle shield (20).
US10780245B2 Method of preparing a ready-to-use urinary catheter and a catheter assembly for use in said method
A method of preparing a ready-to-use catheter by providing a catheter assembly that has a first compartment that includes a catheter therein. The catheter includes on at least a part of its surface an exterior coating designed to reduce the coefficient of friction after treatment with a liquid swelling medium, and a second compartment containing a liquid swelling medium. The method includes sterilising the catheter assembly, adding the liquid swelling medium to the first compartment for wetting/activating the exterior coating of the catheter, and storing the ready-to-use catheter. By using the method according to the invention, the sterilisation of the catheter is effectuated in a dry-state, ensuring that the known problems with wet-sterilisation are completely eliminated and the need for preparing complicated and expensive liquid swelling mediums are no longer required.
US10780244B2 Catheter in a bag without additional packaging
A urinary catheter set includes a urine collection bag formed into an outer packaging for the urinary catheter set, and a urinary catheter positioned inside of the urine collection bag.
US10780243B2 Method and apparatus for treatment of human urinary incontinence
A method and apparatus for treatment of human urinary incontinence may include a flexible tube, a retainer member for the tube, and a valve in the tube which automatically opens in response to a predetermined pressure level in the bladder acting upon the valve.
US10780240B2 Oral airways
An oral airway includes a first component having a first guiding surface and a second component having a second guiding surface. The first component and the second component are adapted to be removably coupled together such that the first guiding surface and the second guiding surface collectively define and encompass an interior passage through the oral airway that is dimensioned to direct, for example, a fiber-optic scope or an endotracheal tube extending through the interior passage for tracheal intubation. The first and second components are configured to be decoupled and independently removed from a patient's mouth without disrupting an endotracheal tube that has been extended through the conduit for tracheal intubation. The first and second components may be maintained in coupled disposition by an interlocking mechanical structure. The first and second components also may be maintained in coupled disposition by magnetism.
US10780238B2 Method of detecting endotracheal tube misplacement
In an alerting and controlling system, there is a measuring device and a controller. The measuring device is connectable to an endotracheal tube associated with a cuff inflatable below the vocal cords of a subject, for measuring at least one measure being indicative of the presence of leakage of secretions from above the cuff to the lungs of the subject. The controller adjusts inflation of the cuff responsively to the level of the at least one measure such as to reduce or prevent leakage of secretions from above the cuff to the lungs, and alerts that the endotracheal tube is malpositioned in the airway of the subject if an inflation pressure of the cuff exceeds a predetermined threshold.
US10780237B2 Atomizing unit
This atomization unit is provided with a reservoir that holds an aerosol source, an atomization part that atomizes the aerosol source, and a cap body that blocks a supply port for supplying the aerosol source to the reservoir, wherein movement of the cap body away from the reservoir causes the atomization part and/or a power supply member, which electrically connects a power source and the atomization part, to break.
US10780235B2 Syringe pump engagement detection apparatus and methods
Syringe pump apparatus and methods for detecting proper or improper engagement of a syringe pump drive system with a syringe in the syringe pump are disclosed. The apparatus and methods can determine proper or improper engagement between a drive system and the plunger of a syringe in a syringe pump by detecting the force required to move a plunger clip in reverse while restricting flow into the syringe. The apparatus and methods may also be used to determine that a syringe in the syringe pump apparatus is properly connected to a delivery line.
US10780234B2 Dental syringe with stabilizer for removable needle
A cartridge syringe system includes a syringe (5). The syringe has a tip-ward direction and a ring-ward direction. The syringe (5) has a syringe body (9) and an actuator ring (7). A shaft (10) slidably mounts the actuator ring (7) to the syringe body (9), with a harpoon (11) at a tip-ward end of the shaft (10). The syringe body (9) has a spiral mount external to the syringe body (9) for removably mounting a sheath (20) to the syringe body (9), on a cooperating internal spiral sheath mount. The syringe body (9) and the sheath have similar openings. The sheath opening can be rotated to coincide with the syringe body opening, for inserting a needle assembly into the syringe body, or for removing the needle assembly. The sheath opening can be rotated to obstruct the syringe body opening, for retaining the needle assembly in the syringe body.
US10780231B2 Drive mechanism for a drug delivery device and drug delivery device
The present invention concerns a drive mechanism for a drug delivery device comprising a housing having a longitudinal axis, a first feedback element which is movable along the longitudinal axis relative to the housing and a second feedback element, wherein the first feedback element and the second feedback element are adapted to interact with each other thereby providing at least one of tactile and audible feedback during at least one of a dose setting and dose dispensing operation of the drive mechanism. Moreover a drug delivery device incorporating such a drive mechanism is disclosed.
US10780230B2 Auto-injector with a delay system
An autoinjector having a body (1) receiving a reservoir (S) containing fluid and a piston (P); a piston rod (5) movable by an injection spring (8) between a primed position and an injection position; and a visual, audible, and/or tactile indicator for indicating the autoinjector may be removed from the injection site. The autoinjector including a retarding system for delaying actuation of the indicator relative to the end of injection, and including a dashpot (16) containing a fluid, a piston (19) in the dashpot, the dashpot or the piston movable in the body during actuation of the retarding system with the other stationary relative to the body, resulting in the fluid moving out from the dashpot through a flow passage (161; 195) to brake movement.
US10780229B2 Low waste syringe and needle assemblage
A low-waste needle and syringe assembly for injecting a fluid into a patient is provided. The syringe has hatch marks printed on the outer wall of the body to indicate the amount of fluid and/or the concentration of the fluid contained in a fluid chamber of the syringe. A syringe tip defining a substantially frusto-conical interior void extends from an end wall of the syringe. A needle hub holds a needle and is configured so that the hub can be selectively and securedly attached to the syringe. A frusto-conical member of the needle hub matingly engages the frusto-conical void of the syringe tip when the hub is secured to the syringe, forming a fluid-tight seal. A plunger positioned in the fluid chamber can be depressed by a user, and a piston cap attached to the plunger urges fluid in the chamber out of the chamber through the syringe tip and into the needle. The piston cap matingly engages the end wall of the syringe so that substantially all fluid is urged from the chamber to the needle.
US10780228B2 Prefilled container systems
A syringe assembly may include a plunger having a stopper. A barrel may be configured to receive the plunger at an open first end. A tip cap may be removably attached to the second end and may form a chamber within the barrel between the plunger and tip cap. The chamber may be configured to contain a sterilization sensitive material. The barrel may be formed of a plastic material having a high barrier property configured to create a barrier between the sterilization sensitive material and gases produced for sterilization purposes such that the sterilization sensitive material remains unchanged during a sterilization procedure.
US10780221B2 Pulse infusion device system and method
Aspects of the invention are related to a method and a system for administrating an infusion liquid pulse. The system includes a tubing system having an inlet connected to an external reservoir adapted to contain infusion fluids and an outlet connected to a catheter. The tubing system includes a check valve proximate to the inlet and an anti-siphon valve proximate to the outlet. The system further includes an automatic pulse flow generation device. The automatic pulse flow generation device includes an internal reservoir and a bidirectional pump configured to pump infusion fluid from the external reservoir to the internal reservoir and further pump an infusion fluid pulse from the internal reservoir to be injected by the catheter, the infusion liquid pulse has a volume of at least 2 ml and a velocity of at least 5 ml/min.
US10780219B2 Ambulatory infusion pumps and assemblies for use with same
Ambulatory infusion pumps, medicament reservoirs, and medicament sealing assemblies, including a variety of trocar seal assemblies and fill plug seal assemblies, plus related components, as well as component combinations and related methods.
US10780217B2 Ratchet drive for on body delivery system
Ratchet-based drive systems for more reliable and safer drug delivery are provided. The ratchet-based drive systems restrict angular movement and/or linear movement of components that cause a plunger to expel a liquid drug from a drug container. Movement of the components can be restricted to correspond to a predetermined or desired portion of the liquid drug. In the case that control of the drive system is lost or fails, the maximum amount of drug that could be delivered is limited to a known amount, thereby reducing the likelihood of an overdose.
US10780213B2 Hemodialysis system
A drain cassette for a dialysis unit has a fluid channel between venous and arterial connection ports, and a valve may controllably open and close fluid communication between a drain outlet port and the venous connection port or the arterial connection port. A blood circuit assembly and drain cassette may be removable from the dialysis unit, e.g., by hand and without the use of tools. A blood circuit assembly may include a single, unitary member that defines portions of a pair of blood pumps, control valves, channels to accurately position flexible tubing for an occluder, an air trap support, and/or other portions of the assembly. A blood circuit assembly engagement device may assist with retaining a blood circuit assembly on the dialysis unit, and/or with removal of the assembly. An actuator may operate a retainer element and an ejector element that interact with the assembly.
US10780207B2 Axial flow blood pump
The invention generally relates to improved medical blood pump devices, systems, and methods. For example, blood pumps may be provided that include a housing defining a blood flow path between an inlet and an outlet. A rotor may be positioned in the blood flow path. A motor stator may be driven to rotate the rotor to provide the blood flow through the pump. Axial and/or tilt stabilization components may be provided to increase an axial and/or tilt stabilization of the rotor within the blood flow path. In some embodiments, biasing forces are provided that urge the rotor toward a bearing component. The biasing force may be provided by adjusting drive signals of the motor stator. Additionally, or alternatively, one or more magnets (e.g., permanent/stator magnets) may be provided to bias the rotor in the upstream and/or downstream direction (e.g., toward a bearing (chamfer, step, conical), or the like).
US10780205B2 Method for operating a supply device which supplies a liquid to a channel, and supply device, hollow catheter, and catheter pump
The present invention relates to a supply device for a channel (8), in particular within a hollow catheter (1), and to a method for operating a supply device of this type that supplies a channel (8) with a liquid and has two pumps (10, 19) arranged at points of the channel distanced from one another, characterised in that the parameter values of at least one operating parameter of both pumps are coordinated with one another in a controlled manner. As a result of the method, interruption-free and precisely controllable operation is to be ensured with simple structural means, in particular in the case of use of wear-free diaphragm pumps.
US10780203B2 Fluid pouch, system, and method for storing fluid from a tissue site
The illustrative embodiments described herein are directed to an apparatus, system, and method for storing liquid from a tissue site. The apparatus may include a drape having an aperture, and a fluid pouch coupled to the drape such that the fluid pouch is in fluid communication with the aperture. In one embodiment, the fluid pouch is operable to transfer reduced pressure to the aperture such that the liquid from the tissue site is drawn into the fluid pouch. The fluid pouch may have a cavity that stores the liquid that is drawn from the tissue site. In another embodiment, the fluid pouch may include at least one baffle. The fluid pouch may also include a fluid channel at least partially defined by the at least one baffle. The fluid channel may be operable to store liquid from the tissue site when reduced pressure is applied through the fluid channel.
US10780198B2 Electrospinning with sacrificial template for patterning fibrous constructs
Methods are disclosed which combine electrospinning and a sacrificial template, such as with additive manufacturing (AM), to produce fibrous microvascular scaffolds which are biodegradable, porous, and easily handled. In one example, a process for fabricating a fibrous network construct is disclosed. The method includes electrospinning a first layer of fibrous material; printing a micropatterned sacrificial template; transferring the micropatterned sacrificial template onto the electrospun fibers; electrospinning a second layer of fibrous biomaterial onto the micropatterned sacrificial template thereby encapsulating the template and generating a construct with two layers; and removing the sacrificial template, producing a fibrous construct with channels or microstructures formed therein. Also disclosed are fibrous constructs and scaffolds produced by the provided methods.
US10780193B2 Rotary aromatherapy lamp structure
A rotary aromatherapy lamp structure includes an aromatherapy lamp and rotating cover. Abase of the aromatherapy lamp is configured with a control circuit board in electric connection with a fan and heating element and first support, a part of the first support positioned relatively above the fan and heating element is in combination with a container, and the first support above the container is extended with a fulcrum; the rotating cover is covered on the fan, heating element and first support, and the fulcrum is used to prop against an axle center of the fan leaves, allowing a space to be formed between the rotating cover and base and thus allowing the rotating cover to have a rotation mechanism. Whereby, the heating element heats the container to speed the essential oil evaporation, and air flow generated from the fan blows the fan leaves to rotate the rotating cover.
US10780192B2 Microfluidic delivery cartridges and methods of connecting cartridges with microfluidic delivery systems
A method of connecting a cartridge comprising a fluid composition with a microfluidic delivery system is provided. The method includes the steps of: providing a housing comprising electrical contacts, wherein the electrical contacts of the housing are disposed on a first plane; providing a cartridge comprising a reservoir for containing a fluid composition, a die comprising a nozzle, and electrical contacts that are in electrical communication with the die, wherein the electrical contacts of the cartridge are disposed along a second plane that is parallel with the first plane; and connecting the cartridge with the housing by moving the cartridge in a direction parallel with the second plane toward the housing until the electrical contacts of the cartridge are in electrical communication with the electrical contacts of the housing.
US10780189B2 Apparatus, method and system for selectively affecting and/or killing a virus
Certain exemplary embodiments of the present disclosure can provide an apparatus and method for generating at least one radiation can be provided. The exemplary apparatus and/or method can selectively kill and/or affect at least one virus. For example, a radiation source first arrangement can be provided which is configured to generate at least one radiation having one or more wavelengths provided in a range of about 200 nanometers (nm) to about 230 nm, and at least one second arrangement can be provided which is configured to prevent the at least one radiation from having any wavelength that is outside of the range can be provided or which can be substantially harmful to cells of the body.
US10780185B2 Multifunctional nanoparticle bioconjugates for photoacoustic-based recording of cellular membrane potential
A construct for detecting cellular membrane potential includes a nanoparticle operable as an electron donor; a modular peptide attached to the nanoparticle, the peptide comprising a nanoparticle association domain, a motif configured to mediate peptide insertion into the plasma membrane, and at least one attachment point for an electron acceptor positioned at a controlled distance from the nanoparticle; and an electron acceptor. The nanoparticle can be a quantum dot and the electron acceptor can be C60 fullerene. Photoacoustic emission from the construct correlates with cellular membrane potential.
US10780182B2 Methods and compositions for treating metastatic breast cancer and other cancers in the brain
A composition comprising at least one AAV vector formulated for central nervous system delivery is described. The composition comprises at least one expression cassette which contains sequences encoding an anti-neoplastic immunoglobulin construct for delivery to the brain operably linked to expression control sequences therefor and a pharmaceutically acceptable carrier. The anti-neoplastic immunoglobulin construct may be an immunoglobulin modified to have decreased or no measurable affinity for neonatal Fc receptor (FcRn). Also provided are methods of using these constructs in preparing pharmaceutical compositions and uses thereof in anti-neoplastic regimens, particularly for primary and/or metastatic cancers of the brain.
US10780180B2 Compounds and compositions for immunotherapy
The present invention relates to compounds for targeted immunotherapy, as well as compositions comprising the same. Further, the present invention relates to the use of the compounds in the treatment of diseases such as cancer.
US10780177B2 Sulfoalkyl ether cyclodextrin compositions
SAE-CD compositions are provided, along with methods of making and using the same. The SAE-CD compositions comprise a sulfoalkyl ether cyclodextrin having an absorption of less than 0.5 A.U. due to a drug-degrading agent, as determined by UV/vis spectrophotometry at a wavelength of 245 nm to 270 nm for an aqueous solution containing 300 mg of the SAE-CD composition per mL of solution in a cell having a 1 cm path length.
US10780172B2 Docetaxel and human serum albumin complexes
This document relates to non-covalently bound complexes including Docetaxel and human serum albumin. This document also relates to compositions comprising non-covalently bound complexes including Docetaxel and human serum albumin. This document also relates to compositions comprising Docetaxel and human serum albumin, wherein the composition is a clear aqueous solution when the composition is dissolved in an aqueous solution, and wherein the composition has a solubility in an aqueous solution of at least 10 mg/ml. This document also relates to compositions comprising Docetaxel and human serum albumin, wherein the Docetaxel and the human serum albumin in the composition have a ratio by weight from about 1:50 to about 1:1000. This document also relates to compositions consisting essentially of Docetaxel and human serum albumin, wherein the Docetaxel and the human serum albumin in the composition have a ratio by weight from about 1:50 to about 1:1000.
US10780171B2 Reduced and oxidized polysaccharides and methods of use thereof
The present invention is directed to reduced and highly oxidized polysaccharides, such as alginates, that are useful for encapsulating therapeutic or diagnostic agents, or lipid based nanoparticles, e.g., liposomes or virosomes, encapsulating therapeutic or diagnostic agents, prior to their delivery into a subject, as well as methods for making and using them.
US10780169B2 Method of decreasing dermal absorption using composition comprising siloxane polymer
Methods of reducing dermal penetration of at least one active ingredient in a topically applied product using compositions comprising siloxane polymers are disclosed. In some aspects, the active ingredient is an antimicrobial agent, especially benzalkonium chloride, 3-(trimethoxysilyl) propyldimethyloctadecyl ammonium chloride, and combinations thereof.
US10780167B2 Aqueous solution containing n-long-chain acyl acidic amino acid and/or salt thereof, and method for producing same
The present invention provides a method of producing an aqueous solution containing an N—C8-22 acyl acidic amino acid and/or a salt thereof and having pH 8.4-9.5, including the first step for reacting an acidic amino acid and/or a salt thereof with a C8-22 fatty acid chloride in a water solvent at pH 10-13 to form an N—C8-22 acyl acidic amino acid salt, and the second step for adjusting the pH of the aqueous solution after the first step to 8.4-9.5.
US10780163B2 Stable aqueous formulations of adalimumab
The invention provides aqueous pharmaceutical adalimumab compositions suitable for long-term storage of adalimumab, methods of manufacture of these compositions, methods of administration, and kits containing same.
US10780155B2 Streptococcal GlcNac-lacking gylcopolypeptides, cell wall carbohydrates, Streptococcus vaccines, and methods for making and using them
In alternative embodiments, the invention provides vaccines, pharmaceutical compounds and formulations for diagnosing, preventing, treating or ameliorating Group A Streptococcus (GAS), Group C Streptococcus (GCS), or Group A Streptococcus (GGS), infections, or other pathogenic Streptococcus infections. In alternative embodiments, the invention provides compositions such as diagnostic tests, assays, immunoassays and test strips, and methods, for detecting or diagnosing the presence of a Streptococcal infection, e.g., Group A Streptococcus (GAS), Group C Streptococcus (GCS), or Group A Streptococcus (GGS), infections, or other pathogenic Streptococcus infections.
US10780153B2 Malaria antigens and methods of use
The invention is directed to a composition comprising one or more polypeptides or one or more nucleic acid sequences that can induce a protective immune response against Plasmodium species that infect humans. The invention also is directed to a method of using such compositions to induce a protective immune response against a Plasmodium parasite in a mammal.
US10780149B2 Therapeutic use of the botulinum neurotoxin serotype A
A new therapeutic use of botulinum neurotoxin serotype A (Bont/A) is described, in the therapeutic treatment of paralysis caused by spinal cord injury.
US10780147B2 Vault complexes for cytokine delivery
The invention relates to compositions of vault complexes containing recombinant cytokine fusion proteins that include a cytokine and a vault targeting domain, and methods of using the vault complexes to deliver the cytokines to a cell or subject, and methods for using the compositions to treat cancer, such as lung cancer.
US10780143B2 Compositions and methods of use for (pro)renin receptor antagonists
Disclosed are methods of treating kidney disease, infectious or inflammatory diseases, acute kidney injury and hypertension by administering a (pro)renin receptor (PRR) antagonist. In some instances the PRR antagonist is a polypeptide. The PRR antagonist can be a polypeptide having at least 70% identity to the amino acid sequence set forth in SEQ ID NO:2. Also disclosed are methods of decreasing proteinuria and methods of promoting wound healing by administering a PRR antagonist.
US10780142B2 Aloe-hyplex topical formulation and a method of preparation
The present invention relates to aloe-hyplex topical formulation and a method of preparation for multilayer skin delivery of active ingredients to provide skin rejuvenating effect. The aloe-hyplex formulation comprises of: a) aloe vera leaf extract in the range of 5-15% by wt., b) at least one anti-inflammatory agent in the range of 5-15% by wt., c) sodium hyaluronate in the range of 0.001-0.1% by wt., d) glycerin in the range of 50-85% by wt., and e) water in the range of 0.5-5% by wt. The method of preparation of the formulation comprises of mixing and stirring the aloe vera extract, anti-inflammatory agent, sodium hyaluronate, glycerin and water to obtain a homogenous aloe-hyplex formulation.
US10780140B2 Methods of extraction of nitrosylated or nitrated derivatives of ascorbic acid from Myriciaria dubia and methods of synthesis thereof
The present invention relates to methods and strategies for extracting nitrosylated and/or nitrated derivatives and analogs from Myrciaria dubia fruit and for synthesizing the same. The ascorbic acid derivatives and analogs have the chemical structure of: where R1 is ═O, —ONO, —ONO2, or —NH2; R2 is —OH, —ONO, —ONO2, or —NH2; R3 is —OH, —ONO, —ONO2. The extraction method comprises freeze-drying the Myrciaria dubia fruit, mixing the freeze-dried powder with a solvent and separating and drying the supernatant. The synthetic method comprises derivatizing an ascorbic acid via nitrosylation and/or nitration in a buffered ascorbic acid solution, reducing zero or more nitro groups to an amine group, and purifying the ascorbic acid analog.
US10780137B2 Composition to improve gut health and animal performance and methods of making the same
The present invention relates to compositions comprising at least about 8% β-glucans and/or at least about 8% α-fucans, which has a prebiotic effect and act as a replacement for in-feed antibiotics. The present invention also relates to extraction methods to obtain such extracts and various uses for the compositions comprising β-glucans and/or α-fucans.
US10780133B2 Method for protecting liver and a liver protecting agent
An object of the present invention is to provide a protective method for liver comprising the administration of an extract from inflamed tissues inoculated with vaccinia virus to a patient who needs the treatment and to provide a liver protective agent, etc. where such an extract is an active ingredient. In the present invention, it has been recognized that, in hepatocytes, activation of NF-B, expression of NF-B target genes, activation of JNK, apoptosis and fat accumulation can be inhibited or suppressed. The agent containing the extract as an active ingredient is a drug exhibiting less adverse action and high safety. Accordingly, the present invention provides very useful protective method for liver and liver protecting agent.
US10780128B2 Mesenchymal stem cell particles
We describe a particle secreted by a mesenchymal stem cell and comprising at least one biological property of a mesenchymal stem cell. The biological property may comprise a biological activity of a mesenchymal stem cell conditioned medium (MSC-CM) such as cardioprotection or reduction of infarct size. The particle may comprise a vesicle or an exosome.
US10780126B2 Pharmaceutical kit comprising erythrocytes encapsulating a PLP-dependent enzyme and, a non-phosphate PLP precursor
The invention relates to a pharmaceutical kit containing a) an injectable suspension of erythrocytes encapsulating a pyridoxal phosphate (PLP)-dependent enzyme and b) a non-phosphate PLP precursor. The invention further relates to methods of producing component(s) of the kit and to therapeutic treatment methods related to the kit. The PLP-dependent enzyme may be a methioninase, a tyrosine phenol-lyase, a tyrosine aminotransferase or a cystathionine beta-synthase.
US10780123B2 Peptides and combination of peptides of non-canonical origin for use in immunotherapy against different types of cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US10780119B2 Methods and compositions for cellular immunotherapy
The present disclosure relates to genetically modified T cells comprising a transgene encoding an engineered antigen specific receptor, wherein expression of an endogenous gene selected from MNK1, MNK2, or both are inhibited in the genetically modified T cell in order to enhance central memory T cell subsets in cellular immunotherapy compositions.
US10780113B2 Pharmaceutical compositions
Pharmaceutical compositions for oral administration, in particular administration as an oral delivery system to be swallowed directly or capable of disintegration in the oral cavity, comprising iron oxy-hydroxide in high loading.
US10780110B2 Plant medium including an oxygen-enabled composition
A composition including a plant medium and a poly-oxygenated metal hydroxide that comprises a clathrate containing oxygen gas molecules. The poly-oxygenated metal hydroxide may comprise of a poly-oxygenated aluminum hydroxide. The composition may include one or more nutrients. The composition may be in a solid form, a fluid form, or a combination thereof. The poly-oxygenated aluminum hydroxide is soluble in a fluid. In one embodiment, the poly-oxygenated metal hydroxide composition may have particles having a diameter of 212 μm or less, and which may be homogeneous.
US10780108B2 RNAi agents for Hepatitis B virus infection
Described are compositions and methods for inhibition of Hepatitis B virus gene expression. RNA interference (RNAi) agents for inhibiting the expression of Hepatitis B virus gene are described. The HBV RNAi agents disclosed herein may be targeted to cells, such as hepatocytes, for example, by using conjugated targeting ligands. Pharmaceutical compositions comprising one or more HBV RNAi agents optionally with one or more additional therapeutics are also described. Delivery of the described HBV RNAi agents to infected liver in vivo provides for inhibition of HBV gene expression and treatment of diseases and conditions associated with HBV infection.
US10780105B2 Substituted nucleosides, nucleotides and analogs thereof
Disclosed herein are nucleosides, nucleotide analogs, methods of synthesizing nucleotide analogs and methods of treating diseases and/or conditions such as a Filoviridae virus infection with one or more nucleosides and/or nucleotide analogs.
US10780102B2 Triterpenoids with HIV maturation inhibitory activity
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, triterpenoids that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formula I: with X selected from C4-8 cycloalkyl, C4-8 cycloalkenyl, C4-9 spirocycloalkyl, C4-9 spirocycloalkenyl, C4-8 oxacycloalkyl, C4-8 dioxacycloalkyl, C6-8 oxacycloalkenyl, C6-8 dioxacycloalkenyl, C6 cyclodialkenyl, C6 oxacyclodialkenyl, C6-9 oxaspirocycloalkyl and C6-9 oxaspirocycloalkenyl ring, such that X is substituted with A, wherein A is —C1-6 alkyl-halo. These compounds are useful for the treatment of HIV and AIDS.
US10780101B2 Amide derivatives of squalamine for the treatment of infections
A compound of formula (I) in which R′ represents a group —(CRaRb)n—X—(CRcRd)m—[Y—(CReRf)o]t—NR9R10 and X and Y independently represent a group —NR11-, a group —O— or a divalent 5-membered or 6-membered heterocyclic group comprising at least one nitrogen atom, and also the stereoisomers, mixtures of stereoisomers, and/or pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical or veterinary compositions containing the compound of formula (I) and also to the use thereof as medicament, more particularly in the treatment of bacterial, fungal, viral or parasitic infections. Also further disclosed are pharmaceutical or veterinary compositions including the compound of formula (I) in combination with an antibiotic other than such a compound of formula (I).
US10780095B2 Compositions and methods for treating disorders of circadian and diurnal rhythms using prokineticin 2 agonists and antagonists
In alternative embodiments, provided are methods for: modifying circadian rhythmicity or timing in a mammal, treating psychiatric conditions or symptoms due to alterations in a human circadian regulatory system, treating sleep problems in a mammal, or inducing sleep or activity suppression, or causing an arousal or wakening reaction, comprising administration to a mammal or human a compound or composition capable of modifying a prokineticin 2 (PK2) expression or activity, and/or a PKR2 (PK2 receptor), a vasopressin receptor (VR), and/or a melatonin receptor (MR) expression or activity.
US10780087B2 Pharmaceutical composition containing 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy]-N-(methylsulfonyl)acetamide
A stabilized solid preparation containing 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}-N-(methylsulfonyl)acetamide is provided, namely, a solid preparation containing 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}-N-(methylsulfonyl)acetamide and D-mannitol having a specific surface area of 1.0 m2/g or less.
US10780085B2 Oral product
An oral product includes a body that is wholly receivable in an oral cavity. The body includes a mouth-stable polymer matrix, cellulosic fibers embedded in the mouth-stable polymer matrix, and a mouth-soluble binder dispersed in the mouth-stable polymer matrix.
US10780082B2 Macrocycle and composition comprising thereof
A macrocycle represented by formula (I) and a pharmaceutical composition including the macrocycle, or a crystalline form, pharmaceutically acceptable salt, hydrate or solvent compound, stereoisomer, prodrug, or isotopic variant of the macrocycle. The macrocycle and the composition thereof inhibit a protein kinase.
US10780081B2 Method of treating multiple sclerosis employing a LSD1-inhibitor
Provided herein are methods for treating multiple sclerosis using (−) 5-((((trans)-2-(4-(benzyloxy)phenyl)cyclopropyl)amino)methyl)-1,3,4-oxadiazol-2-amine, or a pharmaceutically acceptable salt or solvate thereof.
US10780079B2 Veterinary method of alleviating noise aversion
The invention relates to a method for alleviating noise aversion in animals, particularly dogs, comprising administering to a subject in need thereof an effective amount of dexmedetomidine, medetomidine or a pharmaceutically acceptable salt thereof as the active ingredient. The active ingredient is preferably administered oromucosally, e.g. in the form of an oromucosal gel.
US10780076B2 Inhibition of cancer cell motility
Provided herein are compositions and methods for inhibiting cancer cell motility and/or metastasis. In particular embodiments, KBU2046 (or an analog thereof) and one or more additional therapies (e.g., cancer therapies (e.g., hormone therapies and chemotherapies) are provided to inhibit cancer cell motility, inhibit metastasis, and/or treat cancer (e.g., prostate cancer, lung cancer, breast cancer, colon cancer, etc.).
US10780074B2 Compounds and uses thereof
Compounds of Formula I are described as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric diseases and disorders in a subject in need are also disclosed.
US10780067B2 Endoxifen for local transdermal therapy to the breast
Disclosed are methods and topical formulations for treating and/or preventing cell proliferative diseases and disorders including breast cancer and ductal carcinoma is situ (DCIS) using local transdermal therapy (LTT). The disclosed methods typically include administering topically to the breast or breasts of the patient a topical formulation comprising an effective dose of the tamoxifen metabolite, N-desmethyl-4-hydroxytamoxifen (i.e., endoxifen or ENX) for treating breast cancer. The topical formulation may be described as a transdermal formulation and the topical formulation may comprise, consist essentially of, or consist of endoxifen as an active ingredient.
US10780062B2 Tobacco products
A tobacco product includes a dry powder composition comprising an amount of myo-inositol effective for treating and/or delaying onset of dysplastic lesions in the bronchial airway of an individual. A method for administering myo-inositol to an individual comprises the individual consuming the tobacco product.
US10780060B2 Adjusting particle size in fluorocarbon nanoemulsions
The invention provides devices and methods for adjusting particle size in nanoemulsions of fluorocarbons and perfluorocarbons (e.g., perfluoropentane and perfluorohexane) via sonication (e.g., ultrasonication).
US10780058B2 Nucleic acid nanocapsules for drug delivery and targeted gene knockdown
The present disclosure provides multifunctional nanoparticles. More particularly, the present disclosure relates to multifunctional nanoparticles having one or more of nucleic acid ligands; and methods of using such nanoparticles for treatment and/or diagnosis of diseases and conditions.
US10780048B2 Suspension compositions of cyclosporin A for subconjunctival and periocular injection
The present disclosure relates to suspension formulations and systems for the treatment of ocular conditions. The suspension formulations can include cyclosporin A and in some embodiments, Form 1 or Form 2 cyclosporin A. A delivery system can be provided that includes two parts, a first part containing particles of cyclosporin and a second part containing other components that can be combined with the first part to make a suspension formulation. The suspension can be injected into the subconjunctival or other periocular space to treat ocular conditions, such as dry eye disease.
US10780045B2 Nanoparticles for photodynamic therapy, X-ray induced photodynamic therapy, radiotherapy, chemotherapy, immunotherapy, and any combination thereof
Metal-organic frameworks (MOFs) comprising photosensitizers are described. The MOFs can also include moieties capable of absorbing X-rays and/or scintillation. Optionally, the photosensitizer or a derivative thereof can form a bridging ligand of the MOF. Further optionally, the MOF can comprise inorganic nanoparticles in the cavities or channels of the MOF or can be used in combination with an inorganic nanoparticle. Also described are methods of using MOFs and/or inorganic nanoparticles in photodynamic therapy or in X-ray induced photodynamic therapy, either with or without the co-administration of one or more immunotherapeutic agent and/or one or more chemotherapeutic agent.
US10780037B2 Antimicrobial composition
An aqueous composition with a higher-than-neutral pH includes a significant amount of one or more surfactants and large amounts of osmotically active solutes. This composition, as well as an acidic counterpart and solid materials, can be used in a variety of applications such as wound care, oral care, medical equipment reprocessing, healthcare acquired infection and implant treatment.
US10780032B1 Oral care compositions for active agent delivery
An oral care composition with an aqueous phase, hydrophobic phase, active agent, and optionally emulsifier. A jammed emulsion with aqueous phase, hydrophobic phase, active agent, and optionally emulsifier. An oral care composition with aqueous phase, hydrophobic phase, active agent, and optionally emulsifier. Methods of using disclosed compositions for active agent delivery.
US10780029B2 Triphasic cleansing composition
A cleansing composition, a method of making the cleansing composition and a method of using a cleansing composition, the composition including a first liquid surfactant component; a first solid component, including a plurality of cellulose particles; and a first gaseous component.
US10780028B2 Personal care cleaning product in tablet form
In one aspect, a personal care cleaning composition in tablet form may include a surfactant and a starch composition formed from starch, alcohol and water. The tablet may be formed using a method that includes preparing the starch slurry composition comprising the starch, alcohol and water, preparing a mixture of the starch slurry composition and the surfactant, and pressing the mixture into tablet form. In another aspect, a personal care cleaning composition in tablet form may include a surfactant, a starch composition formed from starch, alcohol and water, sodium carbonate, sodium bicarbonate, citric acid, and glycol ether. The tablet may be formed using a method that includes preparing the starch slurry composition comprising the starch, alcohol and water, preparing a mixture of the starch slurry composition and the surfactant, the sodium carbonate, the sodium bicarbonate, the citric acid and the glycol ether, and pressing the mixture into tablet form.
US10780017B2 Treating sleep apnea with negative pressure
An embodiment of a system for treating sleep apnea includes a collar, a pump, a motor, a sensor, and a controller. The collar is configured to maintain an airway of a subject open while the subject is sleeping by applying, to a throat of the subject, a negative pressure having a magnitude, and the pump is configured to generate the negative pressure. The motor is configured to drive the pump, and the sensor is configured to generate a sense signal that is related to a degree to which the airway is open. And the controller is configured to vary the magnitude of the negative pressure in response to the sense signal. For example, one or more of the pump, motor, sensor, and controller can be secured to the collar such that the system is self-contained, i.e., the entire sleep-apnea system can be worn by the subject.
US10780016B2 Vertical motion adjuster for thermotherapy device
A vertical motion adjuster for a thermotherapy device includes a conveyance unit provided with a movable member configured to move along a mat, a support unit having a first side and a second side, the first side rotatably coupled to one side of the conveyance unit, and an elevation unit installed between the conveyance unit and the support unit and configured to adjust an angle of inclination of the support unit by raising or lowering the second side of the support unit such that the second side of the support unit is moved in the shape of an arc.
US10780015B2 Method and apparatus for visual training
An apparatus for use in visual training of a subject, the apparatus including an at least partially opaque elongate occluder for at least partially occluding a substantially laterally oriented area of a field of view of a first eye so as to define an occluded area and a non-occluded area, and, wherein in use the occluded area moves relative to the field of view, and the subject views: at least one target that extends into the occluded area using both eyes so that the subject perceives an image of the target, the image in the non-occluded area being at least partially based on signals from the first eye and the image in the occluded area being at least partially based on signals from a second eye; and, ensures the target is at least partially aligned in the occluded and non-occluded areas.
US10780011B2 Finger joint rehabilitation exercise aid part
A finger joint rehabilitation exercise aid part includes a rubber part, at least one small bracket, one middle bracket and one large bracket. The small bracket, the middle bracket and the large bracket are fixed on the rubber part and are provided with a fixing hole for fixing a power source. A front end of the rubber part is provided with a finger sheath, and the patient's finger can reach into the finger sheath. As such, according to the finger joint rehabilitation exercise aid part, the rubber part is sheathed on the patient's finger. The rubber part is forced by the power source to bend and straighten and drives the patient's fingers to perform exercise at the same time, thus helping patients perform rehabilitation training.
US10780009B2 Apparatus for locomotion therapy
Apparatus for locomotion therapy is provided which includes a base (11), a first table portion (15) and a tilting mechanism (12, 13) to tilt said first table portion (15) between a horizontal position, an inclined or a vertical position. A foot mechanism (16) is mounted to the first table portion (15). Furthermore, the position of a second table portion (17) is adjustable with respect to the first table portion (15) to adapt the apparatus to patients of different heights.
US10780004B2 Lift control systems for lifting devices and lifting devices comprising the same
Overhead lifts with control systems are disclosed. The overhead lifts may include a lift actuator communicatively coupled to a control system. The control system may include a control unit comprising a processor and a memory having computer readable and executable instructions and at least one port for communicatively coupling the control unit to at least one of a computer, a network, and a data storage device. The processor executes the computer readable and executable instructions to: determine at least one operating characteristic of the overhead lift and an operating time of the overhead lift as the overhead lift is actuated; determine an accumulated load-time parameter for the overhead lift based on the at least one operating characteristic and the operating time; and provide an indication that a component of the overhead lift requires service based on the comparison of the accumulated load-time parameter to a service constant.
US10780003B2 Adjustable ergonomic chair
An office-type chair includes a base, a height-adjustable pedestal extending upward from the base, a seat assembly including a rear seat part and a front seat part, and a linkage system connecting the pedestal to the seat assembly. The linkage system is adapted to pivot the seat assembly between a lowered position to serve as a task chair and an elevated position to serve as an elevated sitting support. A backrest arrangement may extend from the seat assembly. In the lowered position, the front and rear seat parts are both generally horizontally oriented. In the elevated position, the rear seat part may have a slight forward tilt and be positioned higher than in the lowered position, and the front seat part may extend at a downward angle relative to the rear seat part.
US10780001B2 Method of maximizing shipping efficiency of absorbent articles
A process for shipping absorbent products having a substantially airfelt free absorbent core, on pallets, is provided. The loaded pallet comprises a plurality of packages, each having a plurality of disposable absorbent articles disposed within the interior space of the package, wherein the plurality of packages are arranged on the pallet such that the plurality of packages on the pallet exhibit a density of from about 11.0 lbs/ft3 to about 14.6 lbs/ft3.
US10779997B1 Tampon insertion device with depth indicator
A tampon insertion device for inserting a tampon includes a structure for indicating the insertion device is sufficiently inserted into a woman's vagina before deploying the tampon. The tampon insertion device includes a barrel having opposed insertion and proximal end portions and a side wall that defines an interior area therebetween. A tampon is initially positioned in the interior area. A depth indicator having indicia is situated on the side wall of the barrel that is indicative that the barrel is fully inserted, the indicia including one of a recess, a groove, or imprinted matter extending radially about the barrel. The insertion device includes a plunger slidable from a starter configuration extending away from the proximal end portion of the barrel to a deployed configuration positioned downstream inside the interior area. Pressure applied to the plunger causes the plunger to urge the tampon downstream within the interior area.
US10779990B2 Ophthalmic incisional procedure instrument and method
An incisional instrument and method of use for creating accurate, reproducible surgical incisions. An exemplary embodiment includes an incisional instrument configured for attachment to a patient's eye and for use performing arcuate limbal relaxing incisions (LRIs). The incisional instrument is made up of two coaxial, interconnecting pieces: a docking piece and a cutting piece. The docking piece includes a suction mechanism and is configured for being secured to a patient's eye just outside the corneal limbus. The cutting piece is configured to fit flush within the docking piece and includes cutting blades and one or more handles for rotating the cutting piece relative to the docking piece. When assembled, the cutting blades extend beyond the proximal end of the docking piece by a length equal to the desired depth of LRIs to be cut. The incisional instrument further includes measurement markings for properly positioning and measuring incisions.
US10779988B2 Compact ultra-short pulsed laser eye surgery workstation
A compact system for performing laser ophthalmic surgery is disclosed. An embodiment of the system includes a mode-locked fiber oscillator-based ultra-short pulsed laser capable of producing laser pulses in the range of 1 nJ to 5 μJ at a pulse repetition rate of between 5 MHz and 25 MHz, a resonant optical scanner oscillating at a frequency of 200 Hz and 21000 Hz, a scan-line rotator, a movable XY-scan device, a z-scan device, and a controller configured to coordinate with the other components of the system to produce one or more desired incision patterns. The system also includes compact visualization optics for in-process monitoring using a beam-splitter inside the cone of a patient interface used to fixate the patient's eye during surgery. The system can be configured such that eye surgery is performed while the patient is either sitting upright, or lying on his or her back.
US10779987B2 Silver nano electronic ink-printed heating element separation type electric thermotherapy device and manufacturing method therefor
A silver-nano electronic-ink print heating element separation-type electric thermotherapy apparatus includes two or more silver-nano electronic-ink print heating elements that emit heat using a power source applied from a power source unit. The electric thermotherapy apparatus includes a control unit which receives the power source from the power source unit to output a power source on-off signal and a temperature control signal for controlling the two or more silver-nano electronic-ink print heating elements, and the silver-nano electronic-ink print heating elements emitting heat depending on the power source and/or a temperature applied using the control unit, whereby an integral heating element, such as an electric mat, an electric mattress, an electric cushion, a hot-water mat, and an electric carpet, includes two or more divided parts, and thus it is easy to separately use the parts of the heating element and to independently control the temperature for the heating parts.
US10779983B2 Compression foot garment, and therapeutic method for reducing heel pain
A compression foot garment is integrally knit of a body yarn, and adapted for wear on a foot of a user. The foot garment incorporates first and second high compression zones, and a compression release zone between the high compression zones. The first high compression zone is adapted for applying substantially circumferential compression to the foot below the plantar fascia between the calcaneus and metatarso-phalangeal joints and generally around the midfoot. The second high compression zone is adapted for applying substantially circumferential compression to the foot above the calcaneus and generally around an ankle of the user. The first and second high compression zones may comprise elastic yarns integrated with the body yarn. The compression release zone is adapted for applying reduced compression to the foot in an area between the first and second high compression zones.
US10779982B2 Method for designing and producing a customized device, the shape of which is adapted to the user's morphology
A method for manufacturing a customized apparatus with a shape adapted to a specific user's morphology, or a mold for such an apparatus, includes obtaining a description of a generic apparatus, or of the mold for such an apparatus, the generic apparatus being adapted to a generic morphology. A description of the generic morphology and a description of the specific user's morphology is obtained. The descriptions of the generic morphology and of the specific user's morphology are processed to identify a geometric transformation mapping together the generic morphology and the specific user's morphology. The geometric transformation is applied to the description of the generic apparatus, or the description of the mold for such apparatus, in order to define the description of the customized apparatus or the mold therefor. The customized apparatus is then manufactured.
US10779976B2 Apparatus and method for stabilization of procedural catheter in tortuous vessels
For percutaneous minimally-invasive intervention in vessels originating from other tortuous vessels, such as the tortuous aortic arch, guide wires/catheters are used to enable procedural catheters to access the vessels where an interventional procedure is needed. Two new methods for fixing a stabilization wire/catheter and providing the needed tension and stabilization without a second percutaneous access are disclosed (1) using a micro-anchor and pin and (2) using a modified Fogarty Balloon. These methods are also usable for access to and treatment of peripheral embolisms in tortuous vessels as well as renal and other visceral interventions.
US10779974B2 Absorbable endoluminal stent and production method thereof
An absorbable endoluminal stent and method for preparing the same are provided in the present invention. The absorbable endoluminal stent comprises a stent body, a plurality of through holes formed in the stent body, and bioabsorbable polymeric materials filled in the through holes. When the stent is implanted into the blood vessels, damages on stent caused during crimping and expansion processes are reduced. Radical supporting force duration of stent is improved and mechanical properties of stent after implantation are guaranteed by compositing the materials in the through holes and materials of the stent body.
US10779972B2 Drug-filled stents to prevent vessel micro-injuries and methods of manufacture thereof
A stent includes a hollow wire formed into a stent pattern. The hollow wire includes an outer member, a lumen extending longitudinally within the hollow wire, at least one opening extending from an outer surface of the outer member to the lumen, and a surface area component within the hollow wire. The surface area component increases the amount of surface area available for tissue in-growth within the hollow wire. More than one surface area component may be utilized. Each surface area component may be disposed within the lumen or the at least one opening of the hollow wire. A pharmacologically or biologically active agent may be disposed within the lumen.
US10779971B2 Endovascular implant
A plaque tack can be used for holding plaque against blood vessel walls such as in treating atherosclerotic occlusive disease. The plaque tack can be formed as a thin, annular band for holding loose plaque under a spring or other expansion force against a blood vessel wall. Focal elevating elements and/or other features, such as anchors, can be used to exert a holding force on a plaque position while minimizing the amount of material surface area in contact with the plaque or blood vessel wall and reducing the potential of friction with the endoluminal surface. This approach offers clinicians the ability to perform a minimally invasive post-angioplasty treatment and produce a stent-like result without using a stent.
US10779967B2 Stents with dual tissue-wall anchoring features
The present disclosure relates generally to the field of stents for body lumen drainage. In particular, the present disclosure relates to systems and methods for forming a fluid channel between tissue walls of varying thickness using a stent.
US10779963B2 System for amplifying signals from individual nerve fascicles
The present disclosure provides methods and systems for receiving, with processing circuitry of an implant device, an electrical signal from a free tissue graft attached to a portion of a nerve (e.g., a nerve branch or fascicle) through an electrical conductor in electrical communication with the free tissue graft (e.g., muscle graft), the nerve having reinnervated the free tissue graft. The electrical signal from the free tissue graft has a voltage amplitude of greater than or equal to about 150 microvolts. The processing circuitry stores signal data corresponding to the electrical signal from the free tissue graft in a memory accessible to the processing circuitry.
US10779961B2 Method and device for ordering a custom orthopedic device
A method and device for digital measuring and ordering a custom orthopedic device includes an interactive method intended to assist clinicians select, measure and submit precise specifications for patients requiring custom orthopedic devices. The method includes a plurality of menus permitting the clinician to input specifications and submit orders electronically with the specifications and other data packaged together. The method and device include visualization indications to appropriately ensure image capture of a limb from various angles, including posterior, anterior, lateral and medial angles.
US10779959B2 Surgical instrument for implant insertion
The present invention provides an orthopedic surgical tool for moving an implant to a surgical sight and installing the implant. The tool allows the surgeon the ability to navigate the implant through a surgical tube, then rotate the implant after reaching the sight and effect installation of the implant, and then effect its release from the tool. The implant can be rotated at any time during its installation within the constraints of other surgical devices.
US10779950B2 Knee joint implant preventing hyperextension
A knee joint implant that prevents hyperextension includes a femoral component having an anterior surface with reference to the lowermost point of a convex condyle, the anterior surface being configured to have different curvature radii in respective sections thereof, and a bearing component having an anterior surface with reference to the lowermost point of a concave articular surface, the anterior surface being configured to have different curvature radii in respective sections, so that when an extended knee is about to be hyperextended, the convex condyle of the femoral component slides toward the anterior side and is brought into contact with a plurality of points of the concave articular surface of the bearing component, thereby producing resistance so as to suppress hyperextension exceeding a design range due to behavioral habits, a decrease in muscle mass, and the like of the patient.
US10779949B2 Anatomical motion hinged prosthesis
A hinged knee prosthesis comprises a tibial component and a femoral component. The tibial component is configured to attach to a tibia. The tibial component has a bearing surface. The femoral component is configured to hingedly attach to the tibial component and rotate relative to the tibial component. The femoral component comprises a medial condyle and a lateral condyle. The medial and lateral condyles have an eccentric sagittal curvature surface configured to rotate and translate on the bearing surface of the tibial component. A method of rotating a hinged knee through a range of flexion is provided. The method fixedly attaches a femoral component to a tibial component. Axial rotation of the femoral component is induced relative to the tibial component when the hinged knee is flexed.
US10779948B2 Acetabular defect reconstructive prosthesis
The present disclosure provides an acetabular defect reconstructive prosthesis, comprising: an iliac support, the iliac support including a support seat (11) and a connecting wing plate (12) provided on the support seat (11), and the support seat (11) being contacted and matched with an ilium (1); and an acetabular cup (20) rotatably connected with the support seat (11) together. The technical solutions of the present disclosure can effectively solve the problems of reconstruction and long-term stability of a peri-acetabular defect in the related technology.
US10779946B2 Leaflet-testing apparatus
Embodiments of the present disclosure provide an apparatus for testing a plurality of prosthetic heart valve leaflets. The apparatus includes a vertical mount, and a plurality of horizontal bars are movably coupled to the mount. Each bar extends away from the mount along a respective bar-axis that lies on a respective vertical bar-plane. Each bar is configured to support a respective leaflet along the respective bar-axis such that the respective leaflet drapes over the respective bar. The apparatus further includes an image sensor, positioned opposite the mount, facing the plurality of bars and the mount so as to be oriented to acquire an image that includes the plurality of leaflets draped over the plurality of bars. Other embodiments are also described.
US10779945B2 Percutaneous transcatheter repair of heart valves via trans-apical access
Apparatus, systems, and methods are provided for repairing heart valves through percutaneous transcatheter delivery and fixation of annuloplasty rings to heart valves via a trans-apical approach to accessing the heart. A guiding sheath may be introduced into a ventricle of the heart through an access site at an apex of the heart. A distal end of the guiding sheath can be positioned retrograde through the target valve. An annuloplasty ring arranged in a compressed delivery geometry is advanced through the guiding sheath and into a distal portion of the guiding sheath positioned within the atrium of the heart. The distal end of the guiding sheath is retracted, thereby exposing the annuloplasty ring. The annuloplasty ring may be expanded from the delivery geometry to an operable geometry. Anchors on the annuloplasty ring may be deployed to press into and engage tissue of the annulus of the target valve.
US10779944B2 Heart valve leaflet capture device
The invention provides a heart valve leaflet capture device (250) comprising a cardiac catheter probe having a proximal end for manipulating the device (250) and a distal end terminating in a transvalve element (256). The transvalve element (256) is configured to pass through a heart valve generally parallel to a longitudinal axis of the catheter and includes two or three leaflet gripping elements (252). The leaflet gripping elements (252) are individually movable by operation of an associated actuating mechanism (260) between a radially retracted position, in which they are withdrawn with respect to the transvalve element (256), and a capture position, in which they diverge outwardly at an acute angle from the transvalve element (256). In the capture position, each leaflet gripping element (252) defines a convergent capture zone that is directed towards the edges of a target valve leaflet and in which the target valve leaflet may be captured.
US10779942B2 Devices and methods for transcatheter valve loading and implantation
The present disclosure relates to numerous delivery devices and methods for transcatheter prosthetic heart valve loading, deployment and delivery utilizing at least one suture. Disclosed delivery devices utilize improved suture routing methods and configurations that reduce suture tangling and also provide the ability to adjust the prosthetic heart valve expansion and contraction prior to the final release of the prosthetic heart valve from the delivery device.
US10779941B2 Delivery cylinder for prosthetic implant
A delivery cylinder for a prosthetic implant can include a first tubular portion and a second tubular portion. The second tubular portion has a plurality of strut members coupled to the first tubular portion that define a volume for containing the prosthetic implant in a radially compressed state. The strut members can include respective flex regions configured such that application of force to the strut members causes deformation of the flex regions and corresponding radially inward or outward movement of the strut members relative to a longitudinal axis of the delivery cylinder between an expanded configuration and a contracted configuration.
US10779937B2 Transcatheter heart valve with plication window and tissue anchors
The invention relates to a transcatheter heart valve replacement (A61F2/2412), and in particular a device and method for percutaneous annular plication, as a replacement device for a heart valve, whereby the prosthesis has an atrial annular flange or cuff having one or more integral plication windows connected to a pressure actuated flow control member extending into the ventricle, wherein the is a reciprocating mechanical member that is compressed by pressurized working fluid within the heart during ventricular systole.
US10779936B2 Percutaneously-deployable prosthetic tricuspid valve
Devices and methods for the treatment of heart conditions are provided herein. For example, this document provides devices and methods for treating tricuspid valve regurgitation by percutaneously implanting a prosthetic tricuspid valve.
US10779933B2 Device, system and method for anchoring to muscle tissue
An implant for assisting contraction and/or extension of a muscle that includes a stem with an adhesion resistant segment and an anchoring segment wherein at least a portion of each of the adhesion resistant segment and the anchoring segment is configured to be implantable within a muscle and the anchoring segment is positioned on a distal portion of the stem and the adhesion resistant segment is positioned proximally on the stem relative to the anchoring segment.
US10779930B2 Endoluminal prosthesis with steerable branch
An endoluminal prosthesis may include a tubular main graft body including a sidewall and proximal and distal ends. A first stent may be positioned near the proximal end of the main graft body. A second stent may be positioned adjacent to and distal of the first stent. An opening in the sidewall may be positioned longitudinally between a peak of the first stent and a valley of the second stent. A tubular branch may be disposed in the opening. The branch may include first and second end openings. The branch may be flexibly orientable between a retrograde configuration in which the first end opening is oriented toward the distal end and the second end opening is oriented toward the proximal end and an antegrade configuration in which the first end opening is oriented toward the proximal end and the second end opening is oriented toward the distal end.
US10779929B2 Treating eye diseases by deploying a stent
A method of treating an eye of a patient may include positioning an expandable strut structure within at least one of an internal carotid artery, an ophthalmic artery, or an ostium at a junction between the internal carotid artery and the ophthalmic artery. Additionally, the method may include directing blood flow towards the ophthalmic artery via a diverter element associated with the expandable strut structure.
US10779919B2 Interdental cleaning tool
Provided is an interdental cleaning tool which has a simple configuration and can effectively prevent an occurrence of breakage of a core base portion when inserting the interdental cleaning tool into an interdental space or during interdental cleaning without reducing the productivity of the interdental cleaning tool, and provided is a method for manufacturing the interdental cleaning tool. A plurality of cleaning portion recesses (14) which penetrate a cleaning soft portion (21) and form recesses (14a) in a core base portion (12) are formed on each of a first side portion and a second side portion of a cleaning portion (2) at an interval in an axial direction of a cleaning soft portion (21), and at least one of the plurality of cleaning portion recesses (14) is formed so that an opening of the core base portion recess formed in the core base portion has a shape elongated in the axial direction of the cleaning portion.
US10779915B1 System for post-processing orthodontic appliance molds
A system and method for post-processing of polymeric items having a liquid component and a predetermined heat deflection temperature is provided. The system includes a washing station to spray water at elevated temperature and pressure on the items while maintaining the temperature of the item below the heat deflection temperature. Then using a water distillation system to separate the water from the water mixed with the liquid polymer component by evaporating the water using heating coils with surface that is not conducive to adhesion of the liquid polymer component and then condense the water vapor into liquid water. The system may further include a spin station to separate the liquid polymer component by spinning the item. The system may further include one or more processing stations to rinse the item, dry the item, cure the item, remove the item from a tray to which the item may be attached and clean trays after removing the item. A conveyor system may be used to automate the post-processing of the items.
US10779909B2 Method for monitoring an orthodontic treatment
A method including an acquisition, with an acquisition apparatus, of at least one two-dimensional image of arches of a patient, called “updated image”, in actual acquisition conditions, a separator separating lips of the patient in order to improve the visibility of patient's teeth, said separator including a register mark, wherein the representation of the register mark on the updated image is used to recut the updated image and/or to roughly assess the actual acquisition conditions and/or to guide the positioning of the acquisition apparatus at the moment of the acquisition of the updated image and/or to identify a dental situation and/or an action to be achieved by the acquisition apparatus.
US10779907B2 Elongate implant containing a structurally encoded pin, carrier and reading system therefor
A carrier for retaining a plurality of implants each comprising a structurally encoded pin, the structurally encoded pin having a shape or surface characteristics discernable by an imaging modality such as x-ray, fluoroscopy, computed tomography, electromagnetic radiation, ultrasound, visible light, UV light, magnetic resonance imaging, positron emission tomography and neutron imaging, from outside the carrier, the shape or surface characteristics representing structurally encoded data. The invention further discloses a carrier for viewing a plurality of implants, and associated reading systems for reading a plurality of implants. Finally, the invention discloses methods for reading a plurality of implantable devices retained within a carrier.
US10779906B2 Cleaning device with microfiber tails
A cleaning device for lumens includes a plurality of microfiber tails and a flexible leader. The microfiber tails are elongated, flat tails having substantially the same length and width. At two ends of the tails, the width of the tails tapers to form a cone shape. The microfiber tails are oriented in planar parallel relationship to one another or layered on top of one another when laid on a flat surface. The flexible leader has a first end and a second end, the second end of the flexible leader is adapted to be fed through the lumen and pulled by the first end thereof through the lumen, with the microfiber tails also being adapted to be pulled through the lumen due to its being coupled to the second end of the flexible leader.
US10779905B2 Focusing optics for mixed mode surgical laser illumination
Focusing optics for mode mixing may be used to homogenize different modes in an optical fiber used for surgical illumination. A vibration stage may impart mechanical motion to a condenser lens to generate a homogeneous illumination field from a coherent light source.
US10779899B2 Automatic push-out to avoid range of motion limits
Devices, systems, and methods include a teleoperated system including a kinematic structure having a joint, a drive or brake system for controlling the joint, and a computing unit coupled with the drive or brake system. The computing unit is configured to detect that the joint is between a software defined range of motion limit for the joint and a physical range of motion limit for the joint, the software defined range of motion limit being spaced a distance apart from the physical range of motion limit and delay for a duration of time, in response to detecting the joint between the software defined range of motion limit and the physical range of motion limit, applying the drive or brake system to stop motion of the joint.
US10779897B2 Robotic surgical assemblies
A surgical instrument for use with and for selective connection to an instrument drive unit includes an end effector, an instrument drive connector including a plurality of drive assemblies, and a plurality of drive members in mechanical cooperation with the instrument drive connector and the end effector. Each drive assembly of the plurality of drive assemblies includes a drive screw including an elongated threaded body and a drive nut threadedly engaged with the elongated threaded body of the drive screw such that rotation of the drive screw results in longitudinal movement of the drive nut. Each drive member of the plurality of drive members includes a proximal end portion secured to a respective drive nut of one of the plurality of drive assemblies such that longitudinal translation of the respective drive nut causes longitudinal translation of the drive member to drive a function of the end effector.
US10779896B2 Motor interface for parallel drive shafts within an independently rotating member
Mechanisms, assemblies, systems, tools, and methods include an offset drive shaft within an independently rotating member. An example method of transmitting torque through an offset drive shaft routed within a rotatable main shaft includes supporting a main shaft to rotate relative to a base so that the main shaft rotates about a main shaft rotational axis. A drive shaft is supported to rotate relative to the main shaft so that the drive shaft rotates about a drive shaft rotational axis that is offset from the main shaft rotational axis. The drive shaft is engaged with a drive feature having a drive feature rotational axis that is fixed relative to the base as the main shaft rotates. The main shaft is rotated relative to the base. The drive feature is rotated relative to the main shaft so as to rotate the drive shaft relative to the main shaft.
US10779894B2 Surgical navigation system support array
A system (100) and device (300) for mounting and tracking a tracker array during a surgical procedure are described. For example, the system includes a surgical navigation system (700) including a position tracking system (702) configured to track one or more tracker arrays, and a device (300) for mounting a tracker array (306) onto a patient during the surgical procedure. The device includes an intramedullary (IM) canal component (304) configured to be inserted into an IM canal (310) within a bone (312). The device further includes a tracker pin (308) configured to penetrate at least a portion of the bone and engage an inserted end (411, 413) of the IM canal component, and a tracker array (306) affixed to the tracker pin. The IM canal component is configured to engage the IM canal of the bone to stabilize the tracker array during the surgical procedure.
US10779890B2 System and method for performing joint replacement surgery using artificial neural network
This disclosure relates to a system and method for performing joint replacement surgery, and in particular relates to an artificial neural network that uses machine learning to improve patient outcomes. In an example method, the method includes the step of predicting a patient score indicative of a success of a surgical procedure as perceived by a patient using a neural network. Based on the predicted patient score, a surgeon may update a treatment plan in a way that improves the patient's outcome. These and other benefits will be appreciated from the following description.
US10779889B2 Planning support during an interventional procedure
Methods and systems are disclosed herein for improved safer planning support during interventional procedures for inserting stents into a hollow organ of a patient by a guide device. One method includes: providing or recording a three-dimensional image data set of the hollow organ in a first position; segmentation or providing a segmentation of the three-dimensional image data set; providing or recording a two-dimensional image of the guide device introduced into the hollow organ; overlaying the three-dimensional image data set with the two-dimensional image; determining at least one corrected position of one or more section(s) of the hollow organ respectively using the overlaying of the three-dimensional image data set with the two-dimensional image; and determining the respective deformation energy of the hollow organ in the section(s) for the case of removal of the guide device using the previously determined corrected position compared to the first position.
US10779882B2 Electrical ablation devices
An electrical ablation apparatus including first, second, and third electrodes is disclosed. Each of the first and second electrode is configured to be selectively extended outside and selectively retracted inside a distal end of its respective lumen and is configured to diverge from its respective longitudinal axis when extended outside the distal end of its respective lumen. The third electrode is non-rotatable and is configured to be selectively extended outside and selectively retracted inside a distal end of its respective lumen. The first, second and third electrodes are extendable into a tissue treatment region to create a first necrotic zone having a first shape. At least one of the first electrode or the second electrode is selectively rotatable within its respective lumen to create a second necrotic zone having a second shape. The third electrode is configured to positionally secure the electrical ablation apparatus at the tissue treatment region.
US10779878B2 Thermal control devices for electrosurgical instruments
An effector includes a tubular body having a proximal end and a distal end. The effector includes a plug or closure at the distal end of the tubular body; an active electrode at the distal end of the body; an insulator on the body; and one or more return electrodes on the insulator. The body dissipates heat generated by the one or more return electrodes from the distal end of the body to the proximal end of the body.
US10779873B2 Methods of treating nasal airways
A device is described for treating a nasal airway by modifying a property of a nasal tissue of or near a nasal valve of the airway, without using a surgical incision or an implant, to decrease airflow resistance or perceived airflow resistance in the nasal airway. Various embodiments include an elongate shaft, a bipolar radiofrequency delivery member extending from one end of the shaft, and a handle attached to the elongate shaft at an opposite end from the radiofrequency delivery member. The radiofrequency delivery member is sized to be inserted into a nose and configured to at least temporarily deform the nasal tissue and deliver radiofrequency energy. The radiofrequency delivery member includes two rows of protruding electrodes disposed on a tissue contact surface, and the device is configured to deliver radiofrequency energy from one row of electrodes to the other row of electrodes.
US10779861B2 Multipoint fixation implants
Bone anchor assemblies are disclosed herein that can provide for improved fixation as compared with traditional bone anchor assemblies. An exemplary assembly can include a bracket or wing that extends down from the receiver member and accommodates one or more auxiliary bone anchors that augment the fixation of the assembly's primary bone anchor. Another exemplary assembly can include a plate that is seated between the receiver member and the rod and accommodates one or more auxiliary bone anchors that augment the fixation of the assembly's primary bone anchor. Another exemplary assembly can include a hook that extends out from the receiver member to hook onto an anatomical structure or another implant to augment the fixation of the assembly's primary bone anchor. Surgical methods using the bone anchor assemblies described herein are also disclosed.
US10779859B2 Arrangement for the ultrasound-assisted manipulation on the female reproductive organs of large mammals and use of the arrangement
The invention relates to an assembly for ultrasound-assisted manipulation at the female reproductive organs of large mammals, such as rhinoceros, elephant and hippopotamus, and to the use of the assembly. The assembly comprises a support pipe with an end element and a handle piece, a guide pipe provided in the support pipe, a puncture needle, an ultrasound head support provided at the distal end of the support pipe and having accomodators for an ultrasound head and the distal end of the guide pipe, wherein the axis of the ultrasound head and of the distal end of the guide pipe is in each case angled with respect to the horizontal axis of the support pipe such that the position of the tip of the puncture needle is in the ultrasound scan range of the ultrasound head.
US10779858B2 Steerable endoluminal punch
An endoluminal needle or punch is describes wherein the distal end of the endoluminal needle is able to articulate laterally out of the longitudinal axis of the steerable endoluminal needle. The endoluminal needle further comprise a blunted distal end configuration that is minimally traumatic. Under control by the user, at the proximal end of the endoluminal needle, a sharp stylet can be advanced to punch tissue and then be retracted to maximize safety. The endoluminal needle is configured for use within an introducer.
US10779857B2 Device and method for access to interior body regions
A device and method is provided to gain access to interior body regions. The system includes a safety needle, a stylet assembly, a blade assembly, an obturator assembly, a cannula assembly, a handle assembly, an actuator assembly, and a lock assembly. The safety needle accesses an interior body region. The actuator assembly, lock assembly, and handle assembly interact to expose the blade assembly, after which the blade assembly expands the pathway created by the safety needle. The obturator then further expands the pathway and delivers the cannula assembly to the desired location. The safety needle, obturator assembly, blade assembly, handle assembly, actuator assembly, and lock assembly are removed, leaving the cannula assembly in place for future procedures.
US10779856B2 Sensorizing robotic surgical system access ports
A robotic surgical system includes an access port having a plurality of sensors incorporated therein and a surgical instrument having an end effector for use with, and connection to a robot arm. The sensors measure a loading parameter between tissue and the access port when the shaft is inserted through the access port. The sensors wirelessly transmit signals indicative of the loading parameter to a processing unit. The estimated loads at the tip of the end effector of the surgical instrument are provided in real-time to a haptic feedback interface for communicating haptic feedback to a user. The haptic feedback increases or decreases in intensity in response to a specific event, occurrence, or operational characteristic related to the estimated loads.
US10779855B2 Methods and systems for treatment of acute ischemic stroke
An arterial access device has an internal lumen and a proximal port, the arterial access device sized and shaped to be inserted directly into an arterial access site in the common carotid artery such that the lumen provides a passageway for an interventional device to be inserted via the proximal port into the carotid artery. The arterial access device has a distal portion that is configured to be inserted into an arterial pathway through the access site, and a proximal portion configured to extend outward from the access site when the distal portion is in the arterial pathway.
US10779854B2 Penile injection guide and compression device
A conformable guide for directing penile injections has an elastomeric or conformable tube having an open end distally for passing over a glans and a shaft of a penis toward a root of the penis on placement. The conformable guide can have an annulus shaped spirally wrapped portion of the elastomeric tube at the distal end configured to unwrap on placement toward the root. The elastomeric tube has one or more observable injection site locations marked or otherwise indicated on the elastomeric tube when positioned onto the shaft of the penis. The conformable guide is made of a stretchable synthetic polymer.
US10779853B2 Sheath type disposable safety scalpel
A sheath type disposable safety scalpel consists of the blade, handle and sheath, and when the sheath slides forward and backward in relation to the handle, the blade shows the extension and retraction states in the sheath, wherein: the positioning mechanism consists of the button on the sheath and the blade protection locking notch and blade exposure locking notch on the handle, and the unlocking inclined surface is set under the blade protection locking notch and blade protection locking notch, and when the button is pressed and pulled, the locking head touches the unlocking inclined surface and climbs out of the locking notch along the unlocking inclined surface to unlock, so that sheath slides between blade protection locking notch and blade exposure locking notch in relation to the handle. The scalpel breaks the monopolization of traditional positioning mechanism, improves safety of scalpel and improves user hand feeling and sound experience.
US10779852B2 Device suitable for removing matter from inside the lumen and the wall of a body lumen
A device suitable for use in a body lumen and comprises an elongated control member having a distal and a proximal end, and a radially expansible member disposed at or near the distal end and adapted for collection and/or shearing of matter (i.e. thrombus) from a wall of the body lumen (i.e. a vein or an artery). The radially expansible member has a proximal end and a distal end and is adjustable between a contracted orientation and an expanded orientation. The elongated control member comprising a proximal arm connected at or adjacent to the proximal end of the radially expansible member and a distal arm connected at or adjacent to the distal end of the radially expansible member such that movement of one arm relative to the other arm effects adjustment of the diameter or radial strength of the radially expansible member. The device comprises a control mechanism operatively connected to both arms and adapted to provide resistance to the movement of one arm relative to the other. The control mechanism may be a biasing means, a brake means, or both.
US10779847B2 Ultrasonic transducer to waveguide joining
Aspects of the present disclosure include various ultrasonic surgical instruments. At least one disclosed surgical instrument includes a waveguide including a blade and a transducer base plate. The transducer base plate may be coupled to the waveguide to define a tapered joint at an interface between the waveguide and the transducer base plate. The transducer base plate may include first and second sides defining corresponding first and second flat faces configured to receive first and second piezoelectric elements. The first and second piezoelectric elements are configured to operate in a D31 mode.
US10779844B2 Surgical tissue fusion instrument
Surgical tissue fusion instrument having two gripping structures which are movable relative to each other, are designed for gripping and bringing together biological tissue sections, and are assigned heat-generating means designed in such a way that tissue fusion takes place between the biological tissue sections by heat being supplied in the area of the gripping structures. At least one gripping structure is assigned a fluid-conducting system, which is designed to supply at least one liquid or flowable additive to the tissue sections during a tissue fusion process.
US10779843B2 Inverting thrombectomy apparatuses having enhanced tracking
Mechanical thrombectomy apparatuses, and particularly knitted rolling tube mechanical thrombectomy apparatuses configured to have improved tracking for delivery through tortious vessels are described herein. Also described herein are methods of removing clots using a mechanical thrombectomy apparatuses in which the clot is larger than the tractor portion of the mechanical thrombectomy apparatus.
US10779841B2 Drilling driver for placing dental implant
The present disclosure provides a drilling driver for placing a dental implant. The drilling driver includes: a tip part having a first outer diameter and having a cutting edge; a small-diameter part extended from the tip part, and having a second outer diameter smaller than the first outer diameter; and a large-diameter part positioned farther from the tip part than the small-diameter part, and having a third outer diameter larger than the first outer diameter.
US10779837B2 Adjustable arm device for grasping tissues
The present disclosure relates to repair devices configured for use in fixing or approximating tissues, such as cardiac valve tissues and particularly the leaflets of a regurgitant mitral valve. The repair device includes a shaft, a pair of proximal elements pivotally coupled to the shaft and extending from the shaft, and a pair of distal elements pivotally coupled to the shaft and extending from the shaft. The proximal and distal elements are configured so that targeted tissue can be grasped therebetween. The distal elements and/or the proximal elements include adjustable arms that can be extended and retracted to adjust the length of the gripping elements to provide more effective grasping of targeted tissues.
US10779832B2 Circular anvil introduction system with alignment feature
An apparatus is provided for stapling tissue. The apparatus includes an anvil and a trocar selectively coupled with the anvil. The anvil may have an inner opening and a plurality of staple pockets aligned around a surface of the anvil. The anvil may be inserted trans-orally through an esophagus prior to being coupled with the trocar. The trocar may include a shaft and a locking assembly. The locking assembly may secure the anvil in position relative to the trocar when the locking assembly is in the expanded position. The apparatus may also include an alignment assembly to align the staple pockets of the anvil relative to the apparatus. The apparatus may also include an introduction assembly to guide the anvil through the esophagus.
US10779827B2 Surgical stapling device with dissecting tip
A dissecting tip is provided for use with a surgical stapler or instrument. In one embodiment, the dissecting tip is secured to the end effector of a surgical stapler, e.g., to the anvil assembly or cartridge assembly. The dissecting tip extends distally from the end effector and is configured to dissect or separate target tissue from certain tissue, e.g., adherent, connective, joined or other tissue.
US10779824B2 Surgical instrument comprising an articulation system lockable by a closure system
A surgical instrument comprising a shaft, an end effector rotatable relative to said shaft about an articulation joint, an articulation system configured to rotate the end effector, and an articulation lock. The articulation lock is configured to selectively couple the articulation system to a frame of the shaft. In various embodiments, the surgical instrument further comprises a lock plate movable within the shaft frame. In such embodiments, the articulation lock is configured to lock the articulation system to the lock plate.
US10779820B2 Systems and methods for controlling motor speed according to user input for a surgical instrument
A motorized surgical instrument is disclosed. The surgical instrument includes a displacement member, a motor coupled to the displacement member, a display, and a control circuit coupled to the motor and the display. The control circuit is configured to measure distance traveled by the displacement member over a predetermined period of time, cause the display to present a selection menu indicia that is indicative of a velocity mode, receive a user input corresponding to the velocity mode, and set the motor velocity of the displacement member based on the measured distance traveled by the displacement member over the predetermined period of time and the user input.
US10779816B2 Orthopedic implant, method, and kit
Disclosed in an orthopedic implant that comprises a spacer portion having a superior portion and an inferior portion, and a staple portion. The staple portion is integral with the spacer portion and comprises a crown portion and first and second leg portions, the first and second leg portions having distal end that converge front the crown portion and that are composed of a material that has superelastic properties at body temperatures, whereby the first and second leg portions are configured to impart a compressive biasing force when the implant is installed with the legs under tension.
US10779815B2 Suture methods and devices
A barbed suture including a body with barbs on the periphery, a pointed end, and an anchor at one end to resist movement of the suture in the direction of the pointed end is provided. One or more limbs on the anchor may be provided, which may be arcuate, of varying lengths, and of varying distribution about the periphery of the suture body. Other anchor designs are provided. Methods of placing single-directional and bi-directional barbed sutures to approximate the tissue on each side of a wound and to position and support tissue in the absence of a wound, as in cosmetic surgery, are provided, and may include terminal J-stitches or S-stitches. Methods of placement may be made with sharp, pointed ends, which may be needles, or insertion devices. Sinusoidal patterns of sutures that have amplitudes generally perpendicular to the resultant holding force of the suture are provided.
US10779812B2 Devices and methods for suture placement
A suturing device includes an elongate body, a needle holder, an actuator, a needle and a needle retainer. The needle holder extends away from a distal end portion or is provided as part of the distal end portion of the elongate body. The needle holder includes a distal end section having a distal-most tip, and defines a needle passage and a distal opening adjacent the distal-most tip. The actuator is operable between a first operating position and a second operating position. Movement of the actuator from the first operating position toward the second operating position moves the needle in an advance direction. The needle is in the needle passage. The needle retainer engages the needle holder and the needle when the actuator is in the first operating position and inhibits movement of the needle toward distal opening while the actuator is in the first operating position.
US10779811B2 Bone anchor having improved fixation strength
Bone anchors having improved fixation are discussed. The bone anchors include an anchor body and radially protruding ribs that extend approximately parallel to a longitudinal axis of the bone anchor. A leading distal edge of each rib may be configured in a tapered “knife-edge” configuration. Such ribs may mitigate the plow-out effect, preserving contact between the ribs and the surrounding bone along the length of the anchor. Furthermore, such ribs provide increased surface area, improving fixation strength.
US10779807B2 Steerable sheath tube and method for occluding atrial septal defect
A steerable sheath tube has a tubular body having a distal end, a traction wire; and a handle connected to the tubular body. The handle has a lateral branch tube that is coupled to the tubular body at an angle thereof, a slider positioned inside the lateral branch tube for translating movement therein, and a positioning member provided within the lateral branch tube and positioned further from the tubular body than from the slider. One end of the traction wire is fixed on the slider while the other end thereof is fixed at the distal end of the tubular body, and when the slider is moved to come into contact with the positioning member, the distal end of the tubular body is bent to a predetermined angle. A method for occluding an atrial septal defect includes the steps of delivering an occluder from a right internal jugular vein to an atrial septal defect by using the steerable sheath tube, and releasing the occluder to occlude the atrial septal defect.
US10779806B2 Cable sheaths and assemblies for use in curved medical and other tools
A flexible cable sheath includes an outer sleeve, an inner sleeve, and a flexible cable passing through the inner sleeve. The outer sleeve has a plurality of individual segments which are coupled to bend and have limited axial separation. By tensioning the inner sleeve relative to the outer sleeve, the resulting assembly has improved dimensional stability and torsional rigidity.
US10779805B2 Wire guided device
The present subject matter discloses a wire guided device, including a sheath, a working assembly, and a wire guide. The working assembly includes a working portion, configured to contact an intended tissue, and a connector, connecting the working portion and the sheath. The wire guide is disposed at and connected to the working assembly. The wire guide is configured to allow a guide wire to pass through, wherein the wire guide is disposed at a predetermined distance from a distal end of the working assembly. The wire guide and the guide wire do not interfere with an operation of the working portion.
US10779803B2 Devices, systems, and methods using a steerable stylet and flexible needle
A minimally invasive system comprises an elongate instrument that includes a flexible proximal portion, a rigid distal portion, and a lumen extending from a proximal end to a distal end of the elongate instrument. The lumen defines a longitudinal axis of the elongate instrument. The flexible proximal portion is fixedly coupled to the rigid distal portion. The system further comprises a stylet slidably disposed within the elongate instrument. The stylet includes a flexible body fixedly coupled to a steerable portion and includes a sensor. The stylet is movable within the elongate instrument between a retracted condition and an extended configuration. A plurality of actuation cables extend through the stylet and terminate in the steerable portion, which comprises a bend-resistive section and a bendable section. The bendable section includes a plurality of articulable segments linked by the actuation cables and includes a plurality of joint pivots disposed between adjacent articulable segments.
US10779802B2 System and method for determining the fertility phase of a female
An electronic system for determining a fertility phase of a female human comprises a wearable device (1) that includes a first sensor system (101), configured to determine heart rate and heart rate variability of the female human, and a second sensor system (102), configured to determine acceleration of the female human. The electronic system further comprises a processor (13, 30), configured to detect during menstrual cycles sleep phases with resting pulse, using the heart rate variability and the acceleration, to determine a change in the resting pulse during a menstrual cycle using the heart rate, and to determine the fertility phase using a time of the change in the resting pulse. The processor for determining the fertility phase is implemented in the wearable device (1), in a mobile communication device (4), and/or in a cloud-based computer system (3).
US10779799B2 Method for ultrasound elastography through continuous vibration of an ultrasound transducer
A method for imaging an object by ultrasound elastography through continuous vibration of the ultrasound transducer is taught. An actuator directly in contact with the ultrasound transducer continuously vibrates the transducer in an axial direction, inducing shear waves in the tissue and allowing for real-time shear wave imaging. Axial motion of the transducer contaminates the shear wave images of the tissue, and must be suppressed. Therefore, several methods for correcting for shear wave artifact caused by the motion of the transducer are additionally taught.
US10779798B2 Ultrasound three-dimensional (3-D) segmentation
An ultrasound imaging system includes a beamformer configured to generate 2-D images offset from each other based on sweeping motion of a transducer array during a 3-D ultrasound imaging procedure producing volumetric data. The ultrasound imaging system further includes a 2-D mask processor configured to generate a 2-D mask image for each of the 2-D images. Each of the 2-D mask images includes a contour of a predetermined structure of interest in the volumetric data. The ultrasound imaging system further includes a 3-D mask processor configured to segment the structure from the 3-D image with the 2-D mask images, generating a 3-D segmentation.
US10779797B2 Ultrasonic diagnostic system and diagnostic method applicable to wireless communication terminal having various resolution levels
The present disclosure provides an ultrasonic diagnostic system formed of an ultrasonic diagnostic apparatus and a wireless communication terminal and applicable to a wireless communication terminal with various resolution levels, including the ultrasonic diagnostic apparatus which converts frame data obtained by collecting an echo signal at an ultrasonic probe into scan data corresponding to a resolution level of a display screen of the wireless communication terminal and the wireless communication terminal which receives the scan data from the ultrasonic diagnostic apparatus and scan-converts the scan data into an ultrasonic image adequate for the resolution level of the display screen thereof.
US10779793B1 X-ray detector pose estimation in medical imaging
For x-ray detector pose estimation, a machine-learned model is used to estimate locations of markers, including occluded or other non-visible markers, from an image. The locations of the markers, including the non-visible markers are used to determine the pose of the X-ray detector for aligning an X-ray tube with the X-ray detector.
US10779788B2 Registration on setting an alignment of an instrument
A method is disclosed for registration on setting an alignment of an instrument relative to an object during a processing or treatment of the object by the instrument. A working image is registered to a planning image. The working image is recorded in a viewing direction that is selected dependent upon relevant degrees of freedom of the instrument such that the relevant degrees of freedom are the degrees of freedom with the greater registration accuracy. In addition, a robot system is provided which is configured for carrying out the method.
US10779787B2 Method for analyzing image data from a patient after a minimally invasive intervention, analysis apparatus, computer program and electronically readable data storage medium
A method is disclosed for analyzing image data from a patient after a minimally invasive intervention on a lesion, in particular after a tumor ablation on a tumor, wherein a pre-intervention image dataset showing the lesion and an intra- and/or post-intervention, second image dataset showing the intervention region are analyzed. In at least one embodiment of the method, the method includes deriving attribute data describing attributes of the image data from the image datasets at least in part automatically, the attribute data being usable as input data to an artificial intelligence analysis algorithm trained using training data from other patients, and the training data being associated with a ground truth. The method further includes determining, from the attribute data, change information that describes the change in the lesion and/or in the intervention region as a result of the intervention.
US10779776B2 Apparatus for X-ray imaging an object
The present invention relates to an apparatus for X-ray imaging an object. It is described to provide (20) data relating to the detection of X-rays, wherein an X-ray detector is configured to be positioned relative to an X-ray source such that at least a part of a region between the X-ray source and the X-ray detector is an examination region for accommodating an object. An X-ray interferometer arrangement is configured to be positioned relative to the examination region. At least one X-ray dark field factor and at least one transmission factor are determined for the X-ray radiation transmitted through at least part of the object is determined. An intensity of X-ray radiation to be emitted towards the at least part of the object is controlled as a function of the determined at least one dark field factor and the determined at least one transmission factor.
US10779774B2 Method and apparatus for ensuring correct positioning for a radiography acquisition
A method for positioning a body region of a patient for a radiography acquisition by a radiography system includes providing an examination requirement for the body region, pre-positioning the body region in the radiography system for the radiography acquisition, pre-positioning an acquisition unit of the radiography system for the radiography acquisition, producing a three-dimensional positioning acquisition of the body region using a 3D camera system, and producing a preview image from the three-dimensional positioning acquisition. A patient model is generated from the three-dimensional positioning acquisition and the preview image is produced from the patient model, and the preview image depicts a representation as if made using the acquisition unit of the radiography system. The method further includes outputting at least one of the preview image and positioning information based on the preview image. Another embodiment may use an apparatus and computer readable medium to execute the method above.
US10779771B2 Signal processing method and apparatus
A method and apparatus which combines multiple simultaneous signals thought to contain a common periodic component by performing principal component analysis on each of the multiple signals, finding the weight of the first principal component, and then adding the multiple signals together in a weighted sum according to the weight of the first principal component. The method and apparatus further includes a way of combining signals from successive overlapping time windows in real time by differentiating the signal and forming as each output signal sample the value of the preceding signal sample summed with the differential of the signal, weighted by weights based on the amplitude of the differential signal at that time point.
US10779770B2 Seismocardiography
According to an example aspect of the present invention, there is provided an apparatus comprising two charge amplifiers configured to receive input from an acceleration sensor and to each produce one first output signal, a differential amplifier configured to receive the first output signals and to amplify a difference between the first output signals to produce two second outputs signals.
US10779765B2 Wearable physiologic sensing apparatus
The disclosure includes a system for sensing physiologic data. The system can include a flexible configured to wrap around a finger of a user, a first electrode coupled to the flexible strap, and a second electrode coupled to the flexible strap. The system can also include a sensor housing comprising at least one sensor configured to detect physiologic data from the finger and a data receiving module communicatively coupled to the first electrode, the second electrode, and the at least one sensor. The data receiving module can be configured to receive physiologic data from the at least one sensor.
US10779764B2 Systems and methods for proprioceptive stimulation to prevent unintentional falls
Systems, devices, and methods are provided for reducing a risk of unintentional falls in a subject that is at risk for falls. The device includes a sensor and a stimulator. The sensor is configured to be positioned adjacent a body portion of the user that changes orientation when the user sits and stands. The sensor is also configured to emit an activation signal when the user stands and to emit a deactivation signal when the user sits or lies down. The stimulator is in communication with the sensor and is configured to be positioned adjacent one of a calf and a lower back of the user. The stimulator is configured to vibrate at a frequency that stimulates proprioceptors of the user without inducing muscle contractions upon receipt of the activation signal from the sensor and to cease vibration upon receipt of the deactivation signal from the sensor.
US10779756B2 Fluid management and patient monitoring system
A lactate sensor arrangement includes a catheter for withdrawing a test fluid sample, a sensor module for measuring an analyte such as lactate in the sample, and a pumping mechanism. A single uninterrupted flow path extends between the pumping mechanism and the catheter and within the flow path resides a sensor module containing a test chamber. The sensor arrangement also includes a control unit or controller that interfaces with a pumping mechanism driver. The sensor arrangement also includes a source of sensor calibration and anticoagulant solution, such as a reservoir, which has a silicone rubber fill septum, a non-woven Teflon air vent, and a check valve sub-assembly.
US10779753B2 System for analyzing a condition of an animal
A system for analyzing a condition of an animal, wherein the system includes at least an identification unit (2.1) which is arranged to be worn by an animal, wherein the identification unit includes a first transmitter unit (4), a movement sensor (6), and a control unit (8) which is communicatively connected with the transmitter unit and the movement sensor, wherein the system further includes a receiver unit (8) and a computer (10) which is connected with the receiver unit and wherein the system further includes positioning means for measuring a position of the identification unit, wherein the control unit is arranged for, in use, storing and/or processing electronic information of movements of the animal which have been obtained with the movement sensor. The system is further arranged to feed positions of the identification unit measured with the aid of the positioning means to the computer and/or the control unit, wherein the computer and/or the control unit is arranged to process the electronic information about detected movements and the electronic information about the measured positions in combination for analyzing the condition of the animal.
US10779751B2 System and process of utilizing image data to place a member
Disclosed is a system for acquiring and using image data and generating a three-dimensional reconstruction of a subject. The three-dimensional reconstruction can be used to assist in determining various features, including axis and planes of a subject or members placed relative to the subject. The system can be implemented to plan and perform a procedure relative to the subject.
US10779746B2 Task-outcome error signals and their use in brain-machine interfaces
A brain machine interface (BMI) for improving a performance of a subject is provided. The BMI has two decoders that act in real-time and in parallel to each other. The first decoder is for intention execution of a subject's intention. The second decoder is for error detection in a closed-loop error fashion with the first detector and to improve the performance of the first detector. Embodiments of this invention may enable an entirely new way to substantially increase the performance and robustness, user experience, and ultimately the clinical viability of BMI systems.
US10779744B2 Automatic method to delineate or categorize an electrocardiogram
Disclosed is a method for computerizing delineation and/or multi-label classification of an ECG signal, including: applying a neural network to the ECG, labelling the ECG, and optionally displaying the labels according to time with the ECG signal.
US10779739B2 Contactless-type sport training monitor method
The present invention provides a contactless-type sport training monitor method, comprising: selecting at least an image database to recognize a plurality of expressions in the image database; making pre-processing for the plurality of expressions: using a convolutional neural network as a feature point extraction model; acquiring a human image; tracking a first target region and a second target region in the human image; making chrominance-based rPPG trace extraction; using the deep level model to compare the second target region image; and to calculate a post-exercise heart rate recovery achievement ratio, to judge the Rating of Perceived Exertion, and judging whether the human body is under overtraining status or not.
US10779735B2 Image-processing methods for marking plaque fluorescent reaction area and systems therefor
An image-processing method for marking plaque fluorescent reaction areas is provided, including: obtaining a first RGB image of a mouth region; obtaining a second RGB image of the mouth region; respectively converting the first RGB image and the second RGB image into a first HSV image and a second HSV image; obtaining a first average brightness value of the first HSV image and a second average brightness value of the second HSV image; normalizing the first average brightness value or the second average brightness value according the first average brightness value and the second average brightness value to obtain a normalized image; converting the normalized image into a third RGB image, and obtaining a plurality of pixel points of the dental plaque according to the third RGB image and the first RGB image or the second RGB image; and marking the pixel points in the third RGB image.
US10779734B2 Imaging system for combine full-color reflectance and near-infrared imaging
An imaging system for acquisition of NIR and full-color images includes a light source providing visible light and NIR light to an area under observation, such as living tissue, a camera having one or more image sensors configured to separately detect blue reflectance light, green reflectance light, and combined red reflectance light/detected NIR light returned from the area under observation. A controller in signal communication with the light source and the camera is configured to control the light source to continuously illuminate area under observation with temporally continuous blue/green illumination light and with red illumination light and NIR excitation light. At least one of the red illumination light and NIR excitation light are switched on and off periodically in synchronism with the acquisition of red and NIR light images in the camera.