最新美国发明专利第2014-11-11期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

Document	Document Title
US08884162B2	Conductive element and method for manufacturing the same A method for manufacturing a conductive element includes: providing a line segment made of a conductive material, forming a spiral portion at one end of the line segment by joining a plurality of rings, and forming a loop at the other end thereof, so that the line segment forms a conductive rod; and encasing an insulator around the conductive rod and exposing the loop. By winding the line segment, there is no need to remove any material from the line segment, and no waste material is produced, thus lowering the manufacturing cost. A conductive element is also provided.
US08884160B2	Box main body A box main body which can smoothly attach cover members each other and prevent generation of abnormal noise is provided. An electric junction box has the box main body including two covers attached to each other and an electric power distribution unit. The box main body has two covers attached to each other. Furthermore, the box main body has a thin portion arranged in the inner wall of the upper cove, and a tapered portion projecting from a bottom surface of the thin portion toward the peripheral wall of the lower cover, and gradually tapering toward the peripheral wall of the lower cover.
US08884159B2	Photovoltaic devices with metal semiconductor alloy metallization A photovoltaic device, such as a solar cell, having improved performance is provided. In one embodiment, the photovoltaic device includes a multimetal semiconductor alloy layer located on exposed portions of a front side surface of a semiconductor substrate. The multimetal semiconductor alloy layer includes at least a first elemental metal that forms an alloy with a semiconductor material, and a second elemental metal that differs from the first elemental metal and that does not form an alloy with a semiconductor material at the same temperature as the first elemental metal. The photovoltaic device further includes a copper-containing layer located atop the multimetal semiconductor alloy layer.
US08884155B2	Collector grid and interconnect structures for photovoltaic arrays and modules An interconnected arrangement of photovoltaic cells is achieved using novel interconnection components. The interconnection component may comprise a current collector structure, an interconnection structure, or a combination of a current collector and interconnection structure.
US08884154B2	Thin-film solar module contacted on one side and having an inner contact layer A thin-film solar module contacted on one side includes a support layer, a photoactive absorber layer and at least one dopant layer deposited over a surface area of at least one side of the absorber layer so as to form a thin-film packet that is divided into thin-film solar cell areas by insulating separating trenches. The thin-film solar module includes first and second contact systems. The first contact system includes contacts connected by an outer contact layer. The second contact system consists of an inner contact layer covering a side of the solar cell areas that face away from the support layer so as to separately discharge excess charge carriers generated by incident light in the absorber layer. The second contact system includes structures that surround and electrically insulate the contacts, which extend through the inner contact layer from the outer contact layer. The first and second contact systems are electrically conductive and connected in series by series contacts in interconnection areas and electrically insulated from each other by an insulation layer outside of the interconnection areas.
US08884147B1	Method of correlating musical scales and musical chords in a color code, a number code, or both, simultaneously A method of correlating scales or chords that is represented as color codes, number codes, or both. The method involves correlating at least one chord with another. The method also involves correlating scales with one another. Furthermore, the method involves correlating chords with scales as well. Notes of scales or chords are assigned colors. Notes of one scale or chord are assigned one color. Notes of another scale or chord are assigned another color. Then at least one distinguishing color is assigned to notes that occur in more than one scale or chord in the correlation. Also, when chords are correlated with scales, distinguishing colors are assigned to notes that occur in more than one musical concept. When more than two chords or scales are correlated by the method, different distinguishing colors are assigned to notes that occur in three or more scales or chords.
US08884144B2	Drum mounting and tuning system providing unhindered and isolated resonance Some embodiments provide a drum structural framework comprising a top shell mount, bottom shell mount, rod holders, and tension rods. The top shell mount and bottom shell mount are mounted to either ending edge of a drum shell disposed between the two mounts. A first set of the rod holders are coupled to the top shell mount and an aligned second set of the rod holders are coupled to the bottom shell mount. The tension rods link the two sets of rod holders without hindering resonance of the drum shell. Tuning assemblies on the rod holders adjust the distance separating the top shell mount from the bottom shell mount, thereby controlling the force imposed on the drum shell. Each rod holder includes one or more dampeners that isolate energy passing from the drumhead to the shell from also reverberating throughout the structural framework of the tension rods and rod holders.
US08884143B2	Musical instrument Musical instrument having a hollow resonator, and a casing, wherein the resonator comprises a first part and a second part, with a coupling between the first part and the second part, the coupling being bounded by a transition edge between the first part and the second part, wherein the instrument is provided with a sound bridge spaced from the transition edge and one or more tensioning elements for arranging the sound bridge under clamping force in abutting contact onto the exterior of the resonator, wherein at a first outer end the sound bridge is provided with a first contact member which is arranged under clamping force in abutting contact onto the first part of the resonator and wherein at a second outer end the sound bridge is provided with a second contact member arranged under clamping force in abutting contact onto the second part of the resonator.
US08884141B1	Plants and seeds of hybrid corn variety CH374512 According to the invention, there is provided seed and plants of the hybrid corn variety designated CH374512. The invention thus relates to the plants, seeds and tissue cultures of the variety CH374512, and to methods for producing a corn plant produced by crossing a corn plant of variety CH374512 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH374512.
US08884139B1	Plants and seeds of hybrid corn variety CH889624 According to the invention, there is provided seed and plants of the hybrid corn variety designated CH889624. The invention thus relates to the plants, seeds and tissue cultures of the variety CH889624, and to methods for producing a corn plant produced by crossing a corn plant of variety CH889624 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH889624.
US08884138B1	Plants and seeds of corn variety CV932863 According to the invention, there is provided seed and plants of the corn variety designated CV932863. The invention thus relates to the plants, seeds and tissue cultures of the variety CV932863, and to methods for producing a corn plant produced by crossing a corn plant of variety CV932863 with itself or with another corn plant, such as a plant of another variety. The invention further relates to corn seeds and plants produced by crossing plants of variety CV932863 with plants of another variety, such as another inbred line. The invention further relates to the inbred and hybrid genetic complements of plants of variety CV932863.
US08884137B2	Plants and seeds of hybrid corn variety CH816319 According to the invention, there is provided seed and plants of the hybrid corn variety designated CH816319. The invention thus relates to the plants, seeds and tissue cultures of the variety CH816319, and to methods for producing a corn plant produced by crossing a corn plant of variety CH816319 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH816319.
US08884136B2	Plants and seeds of hybrid corn variety CH859703 According to the invention, there is provided seed and plants of the hybrid corn variety designated CH859703. The invention thus relates to the plants, seeds and tissue cultures of the variety CH859703, and to methods for producing a corn plant produced by crossing a corn plant of variety CH859703 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH859703.
US08884131B2	Plants and seeds of hybrid corn variety CH095541 According to the invention, there is provided seed and plants of the hybrid corn variety designated CH095541. The invention thus relates to the plants, seeds and tissue cultures of the variety CH095541, and to methods for producing a corn plant produced by crossing a corn plant of variety CH095541 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH095541.
US08884125B2	Cotton variety 99M-548 A cotton variety, designated 99M-548, the plants and seeds of the cotton variety 99M-548, methods for producing a cotton plant, either varietal or hybrid, produced by crossing the cotton variety 99M-548 with itself or with another cotton plant, and hybrid cotton seeds and plants produced by crossing the variety 99M-548 with another cotton variety or plant and to methods for producing a cotton plant containing in its genetic material one or more transgenes and to the transgenic cotton plants produced by that method. This disclosure also relates to cotton varieties derived from cotton variety 99M-548 including variety 548WRF-CB2-B, to methods for producing other cotton varieties derived from cotton variety 99M-548 and to the varieties derived by the use of those methods.
US08884122B1	Soybean cultivar 23183371 A soybean cultivar designated 23183371 is disclosed. The invention relates to the seeds of soybean cultivar 23183371, to the plants of soybean cultivar 23183371, to the plant parts of soybean cultivar 23183371, and to methods for producing progeny of soybean cultivar 23183371. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 23183371. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 23183371, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 23183371 with another soybean cultivar.
US08884115B2	Soybean variety A1026591 The invention relates to the soybean variety designated A1026591. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1026591. Also provided by the invention are tissue cultures of the soybean variety A1026591 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1026591 with itself or another soybean variety and plants produced by such methods.
US08884111B2	Soybean variety A1026616 The invention relates to the soybean variety designated A1026616. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1026616. Also provided by the invention are tissue cultures of the soybean variety A1026616 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1026616 with itself or another soybean variety and plants produced by such methods.
US08884109B2	Soybean variety A1026419 The invention relates to the soybean variety designated A1026419. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1026419. Also provided by the invention are tissue cultures of the soybean variety A1026419 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1026419 with itself or another soybean variety and plants produced by such methods.
US08884106B2	Soybean variety A1026397 The invention relates to the soybean variety designated A1026397. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1026397. Also provided by the invention are tissue cultures of the soybean variety A1026397 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1026397 with itself or another soybean variety and plants produced by such methods.
US08884101B2	Method of gene introduction into Triticum plant using Agrobacterium, and a method of producing transformed Triticum plant The method of the present invention includes the step of excising one or more portions selected from a radicle, a germ, and an embryonic axis of a plant tissue inoculated with Agrobacterium after cultivation in a coculture medium. The present invention provides a method of gene introduction that can transform a Triticum plant at high efficiency compared to conventionally known Agrobacterium methods, and provides a method of producing a transformed plant.
US08884100B2	Aromatic prenyltransferase from Cannabis Nucleic acid molecules from Cannabis sativa (cannabis, hemp, marijuana) have been isolated and characterized, and encode polypeptides having aromatic prenyltransferase activity. Specifically, the enzyme, CsPT1, is a geranylpyrophosphate olivetolate geranyltransferase, active in the cannabinoid biosynthesis step of prenylation of olivetolic acid to form cannabigerolic acid (CBGA). Expression or over-expression of the nucleic acids alters levels of cannabinoid compounds. The polypeptides may be used in vivo or in vitro to produce cannabinoid compounds.
US08884099B2	Method of plastid transformation in asteraceae, vector for use therein and plants thus obtained The present invention relates to a method for the transformation of plastid genomes of plant species, in particular Asteraceae plant species, comprising the steps of providing a transformation vector carrying a DNA sequence of interest; subjecting a plant material, which comprises plastids, to a transformation treatment in order to allow the plastids to receive the transformation vector; placing the thus treated plant material for a period of time into contact with a culture medium without selection agent; subsequently placing the plant material into contact with a culture medium comprising a selection agent; and refreshing the culture medium comprising a selection agent to allow plant material comprising plastids that have acquired the DNA of interest to grow into transformants.
US08884096B2	Method for the production of antibodies The current invention is related to a method for the production of a human monoclonal antibody from a immunodeficient non-human animal, said method comprising contacting a new borne immunodeficient non-human animal with a human fetal liver stem cell (FL cell) to generate an immune transplanted non-human animal (reconstituted animal), subsequently contacting said reconstituted animal with a antigen, collecting from said reconstituted animal a human cell producing human antibody against said antigen, and isolating said antibody from said antibody producing cell.
US08884095B2	Animal models of neurological disorders The present invention relates to the field of neurological disorders and more particularly to the field of neuropsychiatric disorders. The invention provides non-human, transgenic animal models for brain disorders such as schizophrenia, bipolar disorders, compulsive disorders, addictive disorders and the like. The animals also have applications in the field of GABA neurotransmission and other disorders in which GABA-dependent gene regulation has a role.
US08884094B2	Vacuum bandage packing A vacuum bandage is provided for use with a wound having a wound surface. The bandage is connectable to a vacuum source and includes a wound dressing member having a wound contacting surface, a top surface, and a port configured for communication with the vacuum source. The wound dressing member further includes holes in the wound contacting surface configured for communication with the wound surface of the wound and a passageway between the port and each hole. The vacuum bandage further includes a pack adjacent to the top surface of the member. The pack may include an aperture positioned about the port.
US08884086B2	Renewable diesel refinery strategy A process is described that permits the manufacture of renewable diesel while simultaneously manufacturing petroleum based jet fuel and/or diesel fuel. The process provides for the sulfiding of hydroprocessing catalyst used to hydroprocess sulfur deficient biomass derived feedstocks and permits the use of petroleum derived feedstock deactivated hydroprocessing catalyst in biomass derived feedstock service.
US08884083B2	Selective catalytical dehydrochlorination of hydrochlorofluorocarbons A dehydrochlorination process is disclosed. The process involves contacting RfCHClCH2Cl with a catalyst in a reaction zone to produce a product mixture comprising RfCCl═CH2, wherein said catalyst comprises MY supported on carbon, and wherein Rf is a perfluorinated alkyl group, M=K, Na or Cs, and Y=F, Cl or Br.
US08884082B2	Selective catalytical dehydrochlorination of hydrochlorofluorocarbons A dehydrochlorination process is disclosed. The process involves contacting RfCHClCH2Cl with a carbon catalyst in a reaction zone to produce a product mixture comprising RfCCl═CH2, wherein Rf is a perfluorinated alkyl group.
US08884065B2	Process for producing cycloalkylaromatic compounds In a process for producing a cycloalkylaromatic compound, an aromatic compound and a cyclic olefin are contacted with a first catalyst under conditions effective to produce a reaction product comprising the cycloalkylaromatic compound and at least one non-fused bicyclic by-product. The at least one non-fused bicyclic by-product is then contacted with a second catalyst under conditions effective to convert at least a portion of the at least one non-fused bicyclic by-product to a converted by-product.
US08884063B2	Continuous process for the hydrogenation of 3-cyano-3,5,5-trimethyl-cyclohexylimine The present invention relates to a continuous process for preparing 3-aminomethyl-3,5,5-trimethylcyclohexylamine by reacting a feed stream comprising 3-cyano-3,5,5-trimethylcyclohexylimine with hydrogen and ammonia over hydrogenation catalysts, wherein the basicity of the reaction mixture is increased during the reaction by bringing the reaction mixture into contact with a basic compound which is not ammonia and/or a basic catalyst after part of the 3-cyano-3,5,5-trimethylcyclohexylimine has been reacted.
US08884052B2	Production of diacetoxyethylene by direct acetoxylation In one embodiment, the invention is to a process for producing a vinyl acetate composition by contacting a vinyl acetate stream with acetic acid, ethylene, and oxygen to form a reaction mixture and reacting the reaction mixture in a reactor under conditions effective to form a crude vinyl acetate composition comprising vinyl acetate, water, acetic acid and at least 0.1 wt % diacetoxyethylene.
US08884050B2	Process for production of acrylic acid or its derivatives from hydroxypropionic acid or its derivatives Processes for the catalytic dehydration of hydroxypropionic acid, hydroxypropionic acid derivatives, or mixtures thereof to acrylic acid, acrylic acid derivatives, or mixtures thereof with high yield and selectivity and without significant conversion to undesired side products, such as, acetaldehyde, propanoic acid, and acetic acid, are provided.
US08884046B2	Compounds useful in the synthesis of benzamide compounds Compounds that are useful in the synthesis of 2-amino-4,6-dimethoxybenzamide derivatives and other benzamide compounds.
US08884045B2	Use of an acetic acid wash to prepare low-sulfate 5-sulfoisophthalic acid, mono-lithium salt There is disclosed a process for making a mono-lithium salt of 5-sulfoisophthalic acid (LiSIPA) having less than 500 ppm sulfate. The process uses a reaction mixture of water, a lithium cation producing compound, and 5-sulfoisophthalic acid. The reaction mixture is heated to reflux, cooled, filtered and washed with acetic acid to obtain a high quality LiSIPA having less than 500 ppm sulfate. Also disclosed is a high quality, non-purified reaction product containing a mono-lithium salt of 5-sulfoisophthalic acid and having less than 500 ppm sulfate.
US08884044B2	Ruthenium complexes having (P—P)—coordinated diphosphorus donor ligands and processes for preparing them The invention relates to ruthenium complexes which have a chiral diphosphorus donor ligand and in which the ruthenium has the oxidation state (+11) and the chiral diphosphorus donor ligand has bidentate P—P coordination to the ruthenium. The ruthenium complexes are present in two forms (cationic type A and uncharged type B), are cyclic and have a four- to six-membered ring incorporating the diphosphorus donor ligand. The chiral diphosphorus donor ligands are selected from the group consisting of diphosphines, diphospholanes, diphosphites, diphosphonites and diazaphospholanes. Furthermore, processes for preparing the ruthenium complexes of types A and B, which are based on ligand exchange reactions, are described. The Ru complexes are used as catalysts for homogeneous asymmetric catalysis for preparing organic compounds.
US08884043B2	Oil or fat composition Provided is an oil or fat composition, which has an MCPD-FS content (ppm) of 13 ppm or less, the content being measured by a Deutsche Gesellschaft für Fettwissenschaft (DGF) standard method C-III 18(09), has a diacylglycerol content of 15 mass % or more, and is subjected to deodorization treatment.
US08884034B2	TOFA analogs useful in treating dermatological disorders or conditions This invention is directed to analogs of 5-(tetradecyloxy)-2-furancarboxylic acid (TOFA) and their use in the treatment of dermatological disorders or conditions characterized by sebaceous gland hyperactivity, such as acne and oily skin, and other dermatological disorders and conditions. This invention is also directed to pharmaceutical compositions comprising analogs of TOFA and a pharmaceutically acceptable excipient for dermatological or oral administration. Formula (I)
US08884033B2	Process for preparing aminobenzoylbenzofuran derivatives The disclosure relates to a process for preparing 5-aminobenzoylbenzofuran derivatives of formula I: in which R1 and R2 are as defined in the disclosure; by reduction of a 5-nitrobenzofuran derivative of formula II: using a hydrogen transfer agent, in the presence of palladium-on-charcoal as catalyst and in an ether or an ether mixture as solvent.
US08884032B2	Trioxane monomers and dimers Monomeric and dimeric trioxane fluoroaryl amides, 5-carbon-linked, C-10 non-acetal trioxane dimer esters; trioxane silylamides; and trioxane dimer orthoesters and methods of their use for treating subjects infected with malaria or other parasitic infectious diseases including, but not limited to, toxoplasmic infection; subjects afflicted with psychiatric conditions associated with toxoplasmic infection; and subjects afflicted with cancer.
US08884031B2	Intermediates for the preparation of analogs of halichondrin B Intermediates and methods of their use in the synthesis of analogs of halichondrin B are provided.
US08884029B2	Dye for photoelectric conversion device and photoelectric conversion device A photoelectric conversion device capable of improving conversion efficiency is provided. The photoelectric conversion device includes a work electrode, an opposed electrode, and an electrolyte-containing layer. In the work electrode, a metal oxide semiconductor layer supporting a dye is provided. The dye contains a cyanine compound that has a methine chain, an indolenine skeleton bonded with both ends of the methine chain, and anchor groups introduced to a nitrogen atom included in the indolenine skeleton. Electron injection efficiency to the metal oxide semiconductor layer is improved, and the dye is hardly exfoliated from the metal oxide semiconductor layer.
US08884027B2	Melampomagnolide B derivatives as antileukemic and cytotoxic agents Melampomagnolide B is disclosed as a new antileukemic sesquiterpene. A biotin-conjugated derivative of melampomagnolide B was prepared to elucidate its mechanism of action. Prodrugs of Melampomagnolide B are disclosed.
US08884020B2	Indole compounds Indole derivatives that are useful for treating pain, inflammation and other conditions are described. Certain of the compounds are benzyl derivatives and others are benzoyl derivatives. The compounds are substituted at least at the 3 position of the indole.
US08884019B2	Benzimidazole compound crystal A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
US08884018B2	Process for preparing modulators of cystic fibrosis transmembrane conductance regulator The present invention relates to processes for preparing solid state forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide, including Compound 1 Form A, Compound 1 Form A-HCl, Compound 1 Form B, and Compound 1 Form B-HCl, any combination of these forms, pharmaceutical compositions thereof, and methods of treatment therewith.
US08884016B2	Apixaban preparation process Process for the preparation of apixaban and intermediates useful for the preparation thereof.
US08884008B2	Peptide nucleic acid derivatives with good cell penetration and strong affinity for nucleic acid The present invention provides a novel class of peptide nucleic acid derivatives, which show good cell penetration and strong binding affinity for nucleic acid.
US08884007B2	Hexenone compounds and medical use thereof The present invention relates to a compound of Formula I, or an isomer, pharmaceutically acceptable salt and solvate thereof; to a composition comprising a compound of Formula I, or an isomer, pharmaceutically acceptable salt and solvate thereof, and a pharmaceutically acceptable carrier, excipient or diluent; and also to use of a compound of Formula I, or an isomer, pharmaceutically acceptable salt and solvate thereof for combating apoptosis, or preventing or treating a disease or disorder associated with apoptosis; and especially use for protecting cardiomyocyte, or preventing or treating a disease or disorder associated with cardiomyocyte apoptosis.
US08884006B2	Small-molecule inhibitors of Rac1 in metastatic breast cancer A novel inhibitor of Rac activity based on the structure of the established Rac/Rac-GEF inhibitor NSC23766 is discloses. The compound EHop-016, with an IC50 of 1.1 μM, is a 100-fold more efficient inhibitor of Rac activity than NSC23766. EHop-016 is specific for Rac1 and Rac3 at concentrations ≦5 mM. At higher concentrations, EHop-016 inhibits the close homolog Cdc42. In MDA-MB-435 cells, EHop-016 (≦5 mM) inhibits the association of the Rac-GEF Vav2 with a nucleotide-free Rac1(G15A), which has a high affinity for activated GEFs. EHop-016 does not affect the association of the Rac-GEF Tiam-1 with Rac1(G15A) at similar concentrations. EHop-016 also inhibits the Rac activity of MDA-MB-231 metastatic breast cancer cells and reduces Rac-directed lamellipodia formation in both cell lines. EHop-016 decreases Rac-downstream effects of p21-activated kinase (PAK)1 activity and directed migration of metastatic cancer cells. At low concentrations (<5 μM), EHop-016 does not affect cell viability.
US08884001B2	Preparation of intermediates useful in the synthesis of 2′-cyano-2′-deoxy-N4-palmi-toyl-1-β-D-arabinofuranosylcytosine The present invention relates to a process for preparing a compound of formula 682-4, said process comprising the steps of: (i) converting a compound of formula 682-1 into a compound of formula 682-2; (ii) converting said compound of formula 682-2′ into a compound of formula 682-3; and (iii) converting said compound of formula 682-3 into a compound of formula 682-4. Further aspects of the invention relate to the use of the above process in the preparation of 2′-cyano-2′-deoxy-N4-palmitoyl-1-β-D-arabmofuranosylcytosine, a pyrimidine nucleoside which is therapeutically useful in the treatment and/or prevention of cancer.
US08884000B2	Saporin-L1 inhibitors and uses thereof Inhibitors of saporin-L1 are disclosed, as are related compositions and uses thereof, in particular in cancer therapy that employs saporin-L1-linked immunotoxins.
US08883999B2	Methods and solutions for inhibiting undesired cleaving of labels The invention provides methods and compositions, including, without limitation, algorithms, computer readable media, computer programs, apparatus, and systems for determining the identity of nucleic acids in nucleotide sequences using, for example, data obtained from sequencing by synthesis methods. The methods of the invention include correcting one or more phenomena that are encountered during nucleotide sequencing, such as using sequencing by synthesis methods. These phenomena include, without limitation, sequence lead, sequence lag, spectral crosstalk, and noise resulting from variations in illumination and/or filter responses.
US08883996B2	Methods and compositions for the specific inhibition of gene expression by double-stranded RNA The invention is directed to compositions and methods for selectively reducing the expression of a gene product from a desired target gene in a cell, as well as for treating diseases caused by the expression of the gene. More particularly, the invention is directed to compositions that contain double stranded RNA (“dsRNA”), and methods for preparing them, that are capable of reducing the expression of target genes in eukaryotic cells. The dsRNA has a first oligonucleotide sequence that is between 25 and about 30 nucleotides in length and a second oligonucleotide sequence that anneals to the first sequence under biological conditions. In addition, a region of one of the sequences of the dsRNA having a sequence length of at least 19 nucleotides is sufficiently complementary to a nucleotide sequence of the RNA produced from the target gene to trigger the destruction of the target RNA by the RNAi machinery.
US08883992B2	Humanized anti-CD19 antibodies Isolated nucleic acids encoding anti-CD19 mouse monoclonal antibodies are described herein. Also described are expression vectors, host cells and a method of producing anti-CD19 antibodies.
US08883991B2	Methods and reagents for molecular cloning The present invention provides compositions, methods, and kits for covalently linking nucleic acid molecules. The methods include a strand invasion step. For example, a method of covalently linking double stranded (ds) nucleic acid molecules can include contacting a first ds nucleic acid molecule, which has a topoisomerase linked to a 3′ terminus of one end and has a single stranded 5′ overhang at the same end, with a second ds nucleic acid molecule having a blunt end, such that the 5′ overhang can hybridize to a complementary sequence of the blunt end of the second nucleic acid molecule, and the topoisomerase can covalently link the ds nucleic acid molecules. The methods are simpler and more efficient than previous methods for covalently linking nucleic acid sequences, and the compositions and kits facilitate practicing the methods, including methods of directionally linking two or more ds nucleic acid molecules.
US08883986B2	Macrolide polymorphs, compositions comprising such polymorphs, and methods of use and manufacture thereof The invention relates to novel forms of compounds displaying broad spectrum antibiotic activity, especially crystalline polymorphic forms and amorphous forms of such compounds, compositions comprising such crystalline polymorphic forms and amorphous forms of such compounds, processes for manufacture and use thereof. The compounds and compositions of the invention are useful in the pharmaceutical industry, for example, in the treatment or prevention of diseases or disorders associated with the use of antibiotics, chemotherapies, or antiviral therapies, including, but not limited to, colitis, for example, pseudo-membranous colitis; antibiotic associated diarrhea; and infections due to Clostridium difficile (“C. difficile”), Clostridium perfringens (“C. perfringens”), Staphylococcus species, for example, methicillin-resistant Staphylococcus, or Enterococcus including Vancomycin-resistant enterococci.
US08883983B2	Antigen binding proteins to proprotein convertase subtilisin kexin type 9 (PCSK9) Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described.
US08883982B2	Compositions and methods for increasing serum half-life Provided herein are glycovariant Fc fusion proteins having increased serum half lives. Also provided are methods for increasing the serum half life of an Fc fusion protein by introducing one or more non-endogenous glycosylation sites.
US08883980B2	Antigen binding molecules with increased Fc receptor binding affinity and effector function The present invention relates to antigen binding molecules (ABMs). In particular embodiments, the present invention relates to recombinant monoclonal antibodies, including chimeric, primatized or humanized antibodies specific for human CD20. In addition, the present invention relates to nucleic acid molecules encoding such ABMs, and vectors and host cells comprising such nucleic acid molecules. The invention further relates to methods for producing the ABMs of the invention, and to methods of using these ABMs in treatment of disease. In addition, the present invention relates to ABMs with modified glycosylation having improved therapeutic properties, including antibodies with increased Fc receptor binding and increased effector function.
US08883977B2	MUC1 antibody An objective of the present invention is to provide a MUC1 antibody having high specificity to cancer cells. The objective has been achieved by the present inventors who found that a cancer-specific sugar chain can be specifically recognized in MUC1 and a cancer cell expressing MUC1 having such a cancer cell specific sugar chain can be recognized. The present invention provides an antibody, an antigen-binding fragment thereof or a MUC1-binding molecule, having, for example, 40-fold specificity or more for a cancer-associated structure of MUC1 as compared to that of a normal tissue-associated structure of MUC1.
US08883974B2	Device for enhancing immunostimulatory capabilities of T-cells T-cells are generated with enhanced immunostimulatory capabilities for use in self therapy treatment protocols, by utilizing a biodegradable device with a biodegradable support that has one or more agents that are reactive to T-cell surface moieties. The biodegradable devices are mixed with the T-cells sufficiently so that the one or more agents cross-link with the T-cells' surface moieties and deliver a signal to the T-cells to enhance immunostimulatory capabilities.
US08883972B2	High specificity monoclonal antibody against a protein or a polypeptide having oxidative modification The present invention provides an antibody, which reacts with a FGA or FGA partial peptide in which a part of prolines in the molecule thereof are hydroxylated, and which does not react with an unmodified FGA or FGA partial peptide.
US08883968B2	Method for producing surfactin and salt thereof The method for producing a surfactin or a salt thereof according to the present invention comprises the steps of adding an organic solvent containing a branched alkyl alcohol to a culture fluid containing the surfactin or the salt thereof, or to a solution obtained by removing an insoluble component from the culture fluid, and extracting the surfactin or the salt thereof with the organic solvent,wherein the surfactin or the salt thereof is represented by the formula (1): wherein * indicates an optically active center; X is an amino acid selected from leucine, isoleucine and valine; R is a C9-13 alkyl group or a C9-13 branched alkyl group; and M is an alkali metal, an alkaline earth metal, an optionally-substituted amine or the like.
US08883967B2	Branched amphipathic oligo-peptides that self-assemble into vesicles The present invention provides branched amphipathic peptides and vesicles formed thereof. The peptides comprise a polar/positively charged C-terminal segment, a branch point, and two hydrophobic N-terminal segments extending from the branch point. The vesicles are formed using a plurality of first and second peptides, wherein the first peptide has a different chain length from the second peptide. When a plurality of the first and second peptides are mixed together, they self-assemble to form small spheres defined by a membrane consisting of an interlocking peptide network bilayer and having a liquid-receiving interior space (i.e., hollow core). In the bi-layer, the respective hydrophobic segments of the peptides form beta-sheet structures having a hydrogen bond-stabilized, anti-parallel orientation in which the opposed sequences interlock to form a zipper-like structure in three dimensions. Thus, the peptide assembly (i.e., vesicle) can be held together at reduced concentrations where lipid vesicles would breakdown.
US08883964B2	Compositions comprising modified collagen and uses therefor The invention provides modified collagen and related therapeutic and diagnostic methods.
US08883958B2	Conjugated polymers and their use in optoelectronic devices Disclosed are certain polymeric compounds and their use as organic semiconductors in organic and hybrid optical, optoelectronic, and/or electronic devices such as photovoltaic cells, light emitting diodes, light emitting transistors, and field effect transistors. The disclosed compounds can provide improved device performance, for example, as measured by power conversion efficiency, fill factor, open circuit voltage, field-effect mobility, on/off current ratios, and/or air stability when used in photovoltaic cells or transistors. The disclosed compounds can have good solubility in common solvents enabling device fabrication via solution processes.
US08883950B2	Silicone resin composition, encapsulating material, and light emitting diode device A silicone resin composition contains a silicon-containing component including a silicon atom to which a monovalent hydrocarbon group selected from a saturated hydrocarbon group and an aromatic hydrocarbon group is bonded and a silicon atom to which an alkenyl group is bonded. The number of moles of alkenyl group per 1 g of the silicon-containing component is 200 to 2000 μmol/g.
US08883947B2	Method of forming thin film A vinylidene fluoride homopolymer represented by the formula (4): CF3-(A1)-I (4) wherein A1 represents a structural unit of vinylidene fluoride homopolymer which includes crystal form I alone or as main component and has a number average degree of polymerization of 5 to 12.
US08883946B2	Charge control resin and manufacturing method of the same Here is provided a charge control resin which is prompt in charge rising up, excellent in electrostatic charging propensity and easy in manufacturing. This charge control resin contains a polymer as an active ingredient having a constituent unit represented by following Formula (1) in the Formula (1), R1 is independent of one another, and is a hydrogen atom, a hydroxyl group, a halogen atom, a carboxy-containing group, a straight-chained or branched alkyl group having 1-18 carbon atoms, or a straight-chained or branched alkoxy group having 1-18 carbon atoms; R2 is a hydrogen atom, a hydroxyl group, a halogen atom, a carboxy-containing group, a straight-chained or branched alkyl group having 1-18 carbon atoms, or a straight-chained or branched alkoxy group having 1-18 carbon atoms; g is a number of 1-3; h is a number of 1-3; and M is a hydrogen atom, an alkali metal, a straight-chained or branched alkyl group having 1-18 carbon atoms, an ammonium radical or a mixture of any of these.
US08883945B2	Surfactant A compound of the formula R1.[(AO)n.—R2]m (I) where: R1 is the residue of a group having at least m active hydrogen atoms; AO is an alkylene oxide residue; each n is independently from 1 to 100; m is at least 2; and each R2 is independently H, a C1 to C21 hydrocarbyl, or an acyl group —OC.R3, where R3 is a C1 to C21 hydrocarbyl group, wherein on average greater than one of the R2 groups is or comprises a C4 to C21 hydrocarbyl group comprising at least two ethylenic double bonds. The compounds are particularly suitable for use in preparing aqueous emulsions or dispersions of resins and polymers, especially alkyd resins.
US08883942B2	Terminally unsaturated, oxetane-based macromonomers, and methods for the production thereof A process for preparing a macromonomer by cationic ring-opening polymerization of at least one hydroxyoxetane with a terminally ethylenically unsaturated starter molecule free of allyl groups in a molar ratio (hydroxyoxetane(s):starter molecule) of (100:1) to (1:1) in the presence of at least one suitable catalyst; macromononomers obtainable therefrom and use thereof.
US08883937B2	Cyclic compound, manufacturing method therefor, radiation-sensitive composition, and method for forming a resist pattern A cyclic compound represented by formula (1): wherein L, R1, R′, and m are as defined in the specification. The cyclic compound of formula (1) is highly soluble to a safety solvent, highly sensitive, and capable of forming resist patterns with good profile. Therefore, the cyclic compound is useful as a component of a radiation-sensitive composition.
US08883933B2	Filter element and process for producing a filter element The invention relates to a hotmelt adhesive including a hotmelt adhesive mixture, the mixture having a 15-85% by weight of a first polyester-based hotmelt adhesive and a 15-85% by weight of a second, polyamide-based hotmelt adhesive.
US08883931B2	Polynitrones and use thereof for cross-linking unsaturated polymers The present invention relates to polyfunctional nitrones (optionally in the form of nitrone-terminated polymers) and to their use as crosslinking agents and matting agents, preferably for producing stable molding compounds, knifing fillers, and use thereof in inks, coatings, and adhesives. Low crosslinking temperatures characterize the invention. Through the use of polyfunctional nitrones it is possible for all unsaturated polymers to be cured, solidified and/or structured at low temperatures, preferably without use of a catalyst. Depending on the amount of nitrone-terminated polymers and/or low molecular mass polyfunctional nitrone used it is possible to exert a strong influence over the optical and the mechanical properties of the coated surfaces. By optical properties are meant, among others, the gloss of the coating systems and the surface structuring, e.g., the matte effect.
US08883928B2	Silicone-containing polymeric materials with hydrolyzable groups The invention provides a silicone hydrogel contact lens including a hydrolyzable units. The hydrolyzable units can be converted by hydrolysis into a hydrophilic units which is capable of imparting the silicone hydrogel contact lens a hydrophilic surface without post-curing surface treatment. The invention also provides an actinically crosslinkable prepolymer including hydrolyzable units and use of the prepolymer of the invention. In addition, the invention provides a method for making wettable silicone hydrogel contact lens without posterior surface treatments other than hydrolysis.
US08883927B2	Radial multi-block copolymers A process for making a radial multi-block copolymer, comprising: (a) anionically polymerizing styrene monomer A1, at least one monovinylarene monomer A2 other than styrene and at least one conjugated diene monomer B using a lithium-based initiator to form block copolymer chains; (b) adding a metal alkyl compound other than the lithium-based initiator after initiating anionic polymerization in step (a), wherein the molar ratio of the metal alkyl compound to lithium is greater than about 2.0; and (c) adding a coupling agent having more than two functional groups to form the radial multi-block copolymer, wherein the radial multi-block copolymer comprises a residue Z derived from the coupling agent and block copolymer chains from step (b) coupled to the residue Z.
US08883922B2	Pressure-sensitive adhesive compositions, pressure-sensitive adhesive layers, and pressure-sensitive adhesive sheets Provided are a pressure-sensitive adhesive composition that is produced with no tin compound, has a sufficiently long pot life, and can be rapidly crosslinked in the process of forming a pressure-sensitive adhesive layer; and a pressure-sensitive adhesive layer and a pressure-sensitive adhesive sheet each produced using such a pressure-sensitive adhesive composition. A pressure-sensitive adhesive composition, comprising: 100 parts by weight of an acrylic polymer (A) having an active hydrogen-containing functional group; 0.1 parts by weight to 10 parts by weight of an isocyanate crosslinking agent (B); 0.002 parts by weight to 0.5 parts by weight of a catalyst (C) having an iron active center; and a compound (D) capable of undergoing keto-enol tautomerism, wherein the weight ratio (D/C) of the compound (D) capable of undergoing keto-enol tautomerism to the catalyst (C) having an iron active center is from 3 to 70.
US08883921B2	Process for cross-linked polyethylene production A method of producing a silane cross-linked polyethylene is disclosed which includes maleating a polyethylene polymer to form a maleated polyethylene and reacting the maleated polyethylene with a primary or secondary amino silane to form a silane-grafted polyethylene. The method further includes treating the silane-grafted polyethylene in a moisture curing process to form the silane cross-linked polyethylene.
US08883917B1	Nylon polymers having a low coefficient of friction and method for the manufacture thereof A method for the preparation of a polyamide-based composition provides for the substantially uniform dispersion of particulate silica and, optionally, mineral oil and any other lubricant additive, within a polyamide matrix. The method includes mixing particulate silica, and optionally, mineral oil and other lubricant additives, to one or more polyamide-producing monomers, and water, to form an emulsion or suspension wherein the particulate silica (and mineral oil and other lubricant additives, when added) are substantially uniformly dispersed therein, and then in situ polymerizing the monomer(s) to provide a polyamide matrix wherein the particulate silica, and optional mineral oil and other optional lubricant additives, remain substantially uniformly dispersed in the resulting polyamide matrix to form the polyamide-based composition. A polyamide-based composition comprising a polyamide matrix having silica and optionally, mineral oil and other lubricant additives, substantially uniformly dispersed within the polyamide matrix is also provided.
US08883909B2	Gelatinous vibration reducing composition and method of making the same A gelatinous vibration reducing composition comprises a poly-alpha-olefin component and polymeric granules. A method of forming the gelatinous vibration reducing composition comprises the steps of providing the poly-alpha-olefin component, providing the polymeric granules, and combining the poly-alpha-olefin component and the polymeric granules to form the gelatinous vibration reducing composition. A method for reducing vibration transmissivity of an article defining a cavity comprises the steps of providing a gelatinous vibration reducing composition comprising the poly-alpha-olefin component and the polymeric granules, providing the article defining the cavity, and disposing the gelatinous vibration reducing composition into the cavity of the article for reducing vibration transmissivity of the article.
US08883898B2	Method for impregnating continuous fibres with a composite polymer matrix containing a grafted fluorinated polymer The invention relates to a method for the impregnation of continuous fibers that comprises coating said fibers with a polymer matrix containing: (a) at least one fluorinated polymer grafted with at least one carboxylic polar function and (b) optionally at least one fluorinated nongrafted polymer. The invention also relates to the composite fibers that can be obtained by said method and to the use thereof.
US08883891B2	Ionic liquid-polymer gel membrane with improved gas permeability, and preparation method thereof The present invention relates to an ionic liquid-polymer gel membrane with improved gas permeability, and a preparation method thereof, and more specifically, to a membrane prepared to allow an ionic liquid to be dispersed in a polymer gel, thereby improving gas permeability. Particularly, the present invention relates to an ionic liquid-polymer gel membrane wherein membrane selectivity and permeability exceed an upper bound by increasing the amount of dispersed ionic liquid, and a preparation method thereof. The preparation method of the membrane for separating a specific gas from a mixture gas according to the present invention comprises the following steps of: mixing a polymer, an ionic liquid and PC as a solvent to prepare a mixture solution; and drying the mixture solution to remove the solvent from the mixture solution. In addition, the polymer is polyvinylidene fluoride-hexafluoropropyl copolymer (PVdF-HFP), and the ionic liquid is 1-ethyl-3-methylimidazolium tetrafluoroborate ([emim][BF4]).
US08883890B2	Crepe agent composition and method for producing crepe paper A crepe agent composition that forms a layer having excellent durability and a method for producing a crepe paper using the same. The crepe agent composition is to be applied to a surface of a cylindrical dryer, and contains an inorganic solid lubricant, a dispersant for dispersing the inorganic solid lubricant, a thermosetting polymer for fixing the inorganic solid lubricant to the surface of the cylindrical dryer, and water as a solvent, the inorganic solid lubricant having a particle diameter of 0.5 to 20 μm.
US08883884B2	Pneumatic tire The present invention is directed to a pneumatic tire comprising at least one component, the at least one component comprising a polymer blend comprising a copolymer and an additional polymer, the copolymer comprising: a polymeric backbone chain derived from a monomer comprising at least one conjugated diene monomer and optionally at least one vinyl aromatic monomer; and polymeric sidechains bonded to the backbone chain, the sidechains comprising a polymer immiscible with the backbone; the additional polymer consisting of a polymer miscible with the polymeric sidechains.
US08883883B2	Resin composition for encapsulating semiconductor and semiconductor device Disclosed is a resin composition for encapsulating a semiconductor including a phenol resin (A) having one or more components containing a component (A1) composed of a polymer having a first structural unit and a second structural unit, an epoxy resin (B), and an inorganic filler (C). Also disclosed is a semiconductor device obtained by encapsulating a semiconductor element with a cured product of the resin composition for encapsulating a semiconductor.
US08883875B2	Kit for adhesion between alginate impression material for dental use and impression tray Disclosed is a kit for adhesion between an alginate impression material for dental use and an impression tray, which contains: (U) a pretreatment agent that contains (I) 100 parts by mass of an organic solvent that has a solubility parameter (δ) of 17.0-23.0 [(MPa)1/2] and (II) 0.1-30 parts by mass of inorganic particles having an average particle diameter of 10 μm or less; and (V1) an adhesive that contains (I) a polyamine compound that contains two or more amino groups in each molecule and (III) a lower alcohol solvent, or (V2) an adhesive that is obtained by mixing (I) a polyamine compound that contains two or more amino groups in each molecule, (II) an organic peroxide and (III) a lower alcohol solvent.
US08883873B2	Polymerizable polymeric photoinitiators and radiation curable compositions A polymerizable polymeric photoinitiator according to Formula (I): wherein: PL represents an n+m+p-functional polymeric core; n and m independently represent an integer from 1 to 30; p represents an integer from 0 to 10; o is 0 or 1; INI represents a group selected from the group consisting of a benzophenone, a thioxanthone, a carbazole, a anthraquinone, a camphor quinone, an α-hydroxyalkylphenone, an α-aminoalkylphenone, an acylphosphine oxide, a bisacyl phosphine oxide, an acylphosphine sulfide, a phenyl glyoxalate, a benzoin ether, a benzyl ketal, an α-dialkoxyacetophenone, a carbazolyl-O-acyl-oxime, an α-haloarylketone and an α-haloaryl sulfone; L3 and L4 represent a substituted or unsubstituted divalent linking group comprising 1 to 14 carbon atoms; A represents a radically polymerizable functional group selected from the group consisting of an acrylate, a methacrylate, a styrene, an acryl amide, a methacryl amide, a maleate, a fumarate, an itaconate, an vinyl ether, an allyl ether, an allyl ester, a maleimide, a vinyl nitrile and a vinyl ester; and R4 represents a substituted or unsubstituted alkyl group. Radiation curable compositions containing the polymerizable polymeric photoinitiator and methods for preparing the polymerizable polymeric photoinitiator are also disclosed.
US08883868B2	Rock dusting compositions and methods of use thereof A rock dusting composition composed of rock dust, e.g., limestone or other mineral dust, water, pumping aid, and polymer, e.g., acrylamide homopolymers, acrylamide copolymers, and combinations thereof, and a method for applying the composition to the surface of a mine. The composition has a water content and a polymer content sufficient to allow the polymer to (i) disperse water molecules within the composition and, upon drying of the composition, (ii) dissipate forming void spaces in the dried composition. The composition is useful for suppressing propagation of a flame and/or fire caused by ignition of coal dust and/or gas within a coal mine.
US08883867B2	Compositions and methods for recycling plastics comprising polymers via solvent treatment Compositions containing a turpentine liquid and methods are disclosed for dissolving, dissolving via melting, selectively dissolving via melting, decomposing plastic comprising a chlorine-containing polymer or thermosetting polymer, and/or co-dissolving plastic with fossil fuel for purifying, separating, recovering or recycling plastic-containing material.
US08883864B2	Process and apparatus for producing emulsion and microcapsules A process and apparatus for rapidly producing an emulsion and microcapsules in a simple manner is provided wherein a dispersion phase is ejected from a dispersion phase-feeding port toward a continuous phase flowing in a microchannel in such a manner that flows of the dispersion phase and the continuous phase cross each other, thereby obtaining microdroplets, formed by the shear force of the continuous phase, having a size smaller than the width of the channel for feeding the dispersion phase.
US08883863B1	Safety of psuedoephedrine drug products A pharmaceutical drug product with at least one drug substance capable of providing immediate release or modified release profiles. The drug substance is selected from an amorphous form with an active pharmaceutical ingredient and a first organic counterion wherein the amorphous form has a phase transition temperature of at least 100° C.; and a morphological form with the active pharmaceutical ingredient and a second organic counterion wherein the morphological form of the drug substance has a phase transition temperature of at least 100° C.
US08883859B1	Viral inhibitor compositions for in vivo therapeutic use comprising a combination of (-) -carvone, geraniol and a further essential oil component The present invention concerns an antiviral composition comprising the following components: R-(−)-2-methyl-5-(prop-1-en-2-yl)-cyclohex-2-enone (also called (−) carvone) and S-(+)-2-methyl-5-(prop-1-en-2-yl)-cyclohex-2-enone (also called (+) carvone) and (2E)-3,7-dimethylocta-2,6-dien-1-ol (also called trans-geraniol) in combination with at least one more component chosen among essential oils components for use in treatment and prevention of diseases caused by DNA enveloped viruses, DNA non-enveloped viruses, RNA enveloped viruses and RNA non-enveloped viruses.
US08883855B2	Role of N-2-hydroxy-ethyl-piperazine-N′-2-ethane sulfonic acid (HEPES) in pain control and reversal of demyelinization injury Compositions and therapeutic uses of HEPES and derivatives in the treatment of pain associated with cancers and side-effects including post-chemotherapy cognitive impairment are disclosed herein. HEPES is also used to treat neurodegenerative and neurological diseases, demyelinization injuries, and side-effects and withdrawal symptoms associated with benzodiazepines, anti-depressants, and other neurological agents.
US08883853B2	N-substituted benzenepropanamide or benzenepropenamide derivatives for use in the treatment of pain and inflammation Compounds for use in the treatment or prophylaxis of pain, including acute and chronic pain (e.g., nociceptive pain, neuropathic pain, headaches, migraine), represented by general formula (I) in which: the dotted line represents a single or a double bond; and R5 and R5′ are independently —H, —OH or —OR6, where R6 is a linear or branched C1-C4 alkyl; X is -0-, —CH2O—, —CH2CH2O—, —CH(CH3)CH2O— or —CH2CH(CH3)O—; Z is —CH2CH2O—, —CH(CH3)CH2O— or —CH2CH(CH3)O—; m is an integer of O or 1; and n is an integer of 0-50. The compounds of the invention are also effective for reducing inflammation and may be used alone or in combination with other analgesics.
US08883851B2	Process for the preparation of vorinostat The present invention relates to an improved process for the preparation of the active pharmaceutical ingredient vorinostat. In particular it relates to a process for preparing vorinostat substantially free from impurities, involving suberic acid, aniline and hydroxylamine as starting materials.
US08883850B2	Naphthalene carboxamide M1 receptor positive allosteric modulators The present invention is directed to naphthalene carboxamide compounds of formula (I) which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimers disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor.
US08883849B2	Treatment of sleep disturbances The present invention provides a new composition for treating pain-associated sleep disturbances, especially shortened sleep duration, comprising ibuprofen and diphenhydramine. The composition is further prepared as a bilayer tablet or caplet, or alternatively as a soft gelatin capsule composition, to prevent interaction between the active ingredients.
US08883844B2	Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions There is provided compositions and methods for the treatment of respiratory conditions such as pulmonary hypertension and sickle-cell disease in a patient in need thereof. The composition and method are for treating a patient in need thereof by inhalation of a composition containing amino acid ester compounds comprising at least one nitric oxide releasing group and pharmaceutical salts thereof.
US08883842B2	Use of HDAC inhibitors for the treatment of myeloma The present invention relates to the use of an HDAC inhibitor, especially an HDAC inhibitor of formula (I) wherein the radicals and symbols have the meanings as defined in the specification, for the preparation of a medicament for the treatment of myeloma, in particular, multiple myeloma, especially myeloma which is resistant to conventional chemotherapy; to a combination comprising an HDAC inhibitor and a compound effecting apoptosis of myeloma cells, preferably bortezomib, for simultaneous, separate or sequential use; to methods of treating myeloma; and to a pharmaceutical composition comprising said combination.
US08883841B2	Oncogenic ras-specific cytotoxic compound and methods of use thereof Embodiments of the present invention provide for methods and compositions comprising an Oncorasin, such as 1-[(4-chlorophenyl)methyl]-1H-Indole-3-carboxaldehyde (oncrasin-1) and/or its analogs or derivatives.
US08883838B2	Pharmaceutical cream compositions and methods of use The present invention provides pharmaceutical cream compositions comprising oxymetazoline and methods for treating rosacea and other skin disorders as described herein using the above cream compositions.
US08883832B2	Compounds, compositions, and methods for preventing metastasis of cancer cells Disclosed are methods for preventing metastasis of cancer cells. The disclosed compounds can be used to prevent the spread of tumor or other types of cancer cells.
US08883828B2	2-aminopyridine analogs as glucokinase activators Provided are compounds that are useful in the treatment and/or prevention of diseases mediated by deficient levels of glucokinase activity, such as diabetes mellitus. Also provided are methods of treating or preventing diseases and disorders characterized by underactivity of glucokinase or which can be treated by activating glucokinase.
US08883823B2	Crystalline forms of a prolyl hydroxylase inhibitor The present disclosure relates to crystalline solid forms of [(4-hydroxy-1-methyl-7-phenoxy-isoquinoline-3-carbonyl)-amino]-acetic acid, the process of preparing the forms, and pharmaceutical compositions and methods of use thereof.
US08883817B2	Combination analgesic employing opioid and neutral antagonist A non-addictive analgesic co-formulation comprising an opioid agonist in an amount sufficient to confer analgesia in a mammalian subject and a neutral opioid antagonist in an amount sufficient to inhibit peripheral effects, and insufficient to block substantial central effects, of the opioid agonist in the subject. Such formulations, and methods of using same, may also deter diversion, inhibit peripheral effects, and reduce addiction liability.
US08883812B2	Piperidinyl pyrimidine amides as Kv7 potassium channel openers The present invention relates to compounds of Formula (I) as described herein or a pharmaceutically acceptable salt thereof, pharmaceutical composition comprising a compound of Formula (I) or a pharmaceutically acceptable salt thereof and methods of treating, or manufacture of a medicament to treat, a disease, disorder, or condition of the central nervous system, including bipolar disorder, depressive disorders, anxiety disorders, cognitive disorders, pain disorders, urogentital disorder, and epilepsy, among the other diseases, disorders or conditions discussed herein as mono-therapy or in combination with another active pharmaceutical ingredient.
US08883809B2	Isoxazole/isoxazoline/combretastatin linked dihydroquinazolinone hybrids as potential anticancer agents and process for the preparation thereof The present invention provides a compound of general formulae 3a-i to 6a-i, 7a-i to 10a-i, 12a-i to 15a-i, 16a-i to 19a-i, 21a-i to 24a-i, 25a-i to 28a-i, 30a-i to 33a-i, 34a-i to 37a-i and 39a-i to 42a-i, 43a-i to 46a-i useful as potential antitumour agents against human cancer cell lines and a process for the preparation thereof.
US08883807B2	Piperidinone carboxamide indane CGRP receptor antagonists The present invention is directed to piperidinone carboxamide indane derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
US08883805B2	Process for the preparation of chiral 8-(3-aminopiperidin-1-yl)-xanthines The invention relates to an improved process for preparing enantiomerically pure 8-(3-aminopiperidin-1-yl)-xanthines.
US08883803B2	Inhibitors of Bruton's tyrosine kinase for the treatment of solid tumors Described herein are irreversible Btk inhibitor compounds, and methods for using such irreversible inhibitors in the treatment of diseases and disorders characterized by the presence or development of solid tumors.
US08883802B2	Co-crystals of a triazolo [4,5-D] pyrimide platelet aggregation inhibitor The present invention relates to novel co-crystal forms of the compound of formula (I); wherein the co-former molecule is selected from glycolic acid, salicylic acid, decanoic (capric) acid, gentisic acid (2,5-dihydroxybenzoic acid), glutaric acid, vanillic acid (4-hydroxy-3-methoxybenzoic acid), succinic acid, malonic acid or maltol (3-hydroxy-2-methyl-4-pyrone); and to processes for their preparation, to pharmaceutical compositions containing such co-crystals, to the use of such co-crystals in the manufacture of a medicament for use in the prevention of arterial thrombotic complications in patients with coronary artery, cerebrovascular or peripheral vascular disease and to methods of treating such diseases in the human or animal body by administering a therapeutically effective amount of a co-crystal of the compound of formula (I).
US08883800B2	Substituted quinazolines, the preparation thereof and the use thereof in pharmaceutical compositions The present invention relates to substituted quinazolines of formula (I): wherein X and Y are defined as in claim 1, the tautomers, stereoisomers, mixtures and salts thereof, which have valuable pharmacological properties, particularly an inhibitory effect on the activity of the enzyme dipeptidylpeptidase-IV (DPP-IV).
US08883793B2	Tubulin inhibitors and methods of using the same Compounds represented by the formula (I) or pharmaceutically acceptable salts thereof: R2—Y—Z-Q-A-R1 Formula (I) wherein R1, R2, Y, Z, Q, and A are as defined. These compounds are inhibitors of tubulin polymerization by binding at colchicines binding site and are useful in the treatment of tumors or mitotic diseases such as cancers, gout, and other conditions associated with abnormal cell proliferation.
US08883792B2	Substituted isoquinoline derivative The present invention provides a novel isoquinoline-6-sulfonamide derivative that is useful as a medicine. The present invention provides an isoquinoline-6-sulfonamide derivative represented by Formula (1), a salt thereof, or a solvate of the derivative or the salt, wherein R1 and R2 each independently represent a hydrogen atom, or the like; R3 and R4 each independently represent a hydrogen atom, an alkyl group, or the like; R5 represents a hydrogen atom, an optionally substituted alkyl group, an optionally substituted alkenyl group, an optionally substituted alkynyl group, an optionally substituted cycloalkyl group, an optionally substituted alkanoyl group, or the like; and A represents a linear or branched alkylene group having 2 to 6 carbon atoms.
US08883790B2	Pharmaceutical combinations The invention provides combinations comprising (or consisting essentially of) one or more ancillary compound(s) and a compound of the formula (I): or salts, tautomers, solvates and N-oxides thereof; wherein R1 is hydroxy or hydrogen; R2 is hydroxy; methoxy or hydrogen; provided that at least one of R1 and R2 is hydroxy; R3 is selected from hydrogen; halogen; cyano; optionally substituted C1-5 hydrocarbyl and optionally substituted C1-5 hydrocarbyloxy; R4 is selected from hydrogen; a group —(O)n—R7 where n is 0 or 1 and R7 is an optionally substituted acyclic C1-5 hydrocarbyl group or a monocyclic carbocyclic or heterocyclic group having 3 to 7 ring members; halogen; cyano; hydroxy; amino; and optionally substituted mono- or di-C1-5 hydrocarbyl-amino; or R3 and R4 together form a monocyclic carbocyclic or heterocyclic ring of 5 to 7 ring members; and NR5R6 forms an optionally substituted bicyclic heterocyclic group having 8 to 12 ring members of which up to 5 ring members are heteroatoms selected from oxygen, nitrogen and sulphur. The combinations have activity as Hsp90 and/or glycogen synthase kinase-3 and/or cyclin dependent kinase and/or aurora kinase inhibitors.
US08883786B2	Glucocorticoid receptor antagonists The present invention relates to compounds of formula I wherein A, n, R1a to R1e and R2 to R5 are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are glucocorticoid receptor antagonists useful for the treatment and/or prevention of diseases such as diabetes, dyslipidemia, obesity, hypertension, cardiovascular diseases, adrenal imbalance or depression.
US08883785B2	Certain kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof Certain chemical entities are provided herein. Also provided are pharmaceutical compositions comprising at least one chemical entity and one or more pharmaceutically acceptable vehicle. Methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of KMO activity are described, which comprise administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are disclosed. These diseases include neurodegenerative disorders such as Huntington's disease. Also described are methods of treatment include administering at least one chemical entity as a single active agent or administering at least one chemical entity in combination with one or more other therapeutic agents. Also provided are methods for screening compounds capable of inhibiting KMO activity.
US08883784B2	Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-xL protein.
US08883783B2	Solid forms comprising N-(5-tert-butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea, compositions thereof, and uses therewith Solid forms comprising N-(5-tert-butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea, compositions comprising the solid forms, methods of making the solid forms and methods of their use for the treatment of various diseases and/or disorders are disclosed.
US08883777B2	Compositions controlling pH range of release and/or release rate The present invention provides a composition controlling a pH range of release and/or a release rate, which contains (i) a thienotriazolodiazepine compound of the formula (I) and (ii) at least one kind of ingredient selected from the group consisting of a water-soluble polymer, an enteric polymer, a water-insoluble polymer and a porous polymer and/or a surfactant, as well as a production method thereof.
US08883776B2	Cycloalkyloxy- and heterocycloalkyloxypyridine compounds as modulators of the histamine H3 receptor Certain cycloalkyloxy- and heterocycloalkyloxypyridine compounds are histamine H3 receptor modulators useful in the treatment of histamine H3 receptor-mediated diseases.
US08883775B2	Treatment of hyperproliferative diseases with vinca alkaloid N-oxide analogs The present invention relates to vinca alkaloid and analog N-oxides having activity for treating hyperproliferative disorders. Further, the invention relates to pharmaceutical compositions and methods of using vinca alkaloid and analog N-oxides, alone or in combination with one or more other active agents or treatments, to treat hyperproliferative disorders.
US08883773B2	Cephem compound having pseudo-catechol group A compound of the formula: wherein X is —N═, —CH═, or the like; W is —CH2— or the like; U is —S— or the like; R1 and R2 are each independently hydrogen, halogen, optionally substituted lower alkyl, or the like; Q is a single bond or the like; R3 is hydrogen or the like; Ring A is a 6-membered aromatic heterocyclic group having 1-3 nitrogen atoms; each R4 is independently hydrogen, halogen, or the like; m is an integer from 0 to 2; G is —C(═O)— or the like; D is a single bond, —NH—, or the like; and E is a cyclic quaternary ammonium group, or an ester, a protected compound at the amino on the ring in the 7-side chain, a pharmaceutically acceptable salt, or a solvate thereof.
US08883765B2	Anti-cytomegalovirus activity of artemisinin-derived dimers Artemisinin-derived monomers and artemisinin dimers are shown to exhibit in-vitro anti-cytomegalovirus (CMV) activity. Artemisinin dimers effectively inhibited CMV replication in human foreskin fibroblasts and human embryonic lung fibroblasts with no cytotoxicity at concentrations required for complete CMV inhibition. Artemisinin dimers were found to be potent and non-cytotoxic inhibitors of CMV replication, which indicates their use as therapeutic agents for the treatment of CMV infection in humans.
US08883762B2	Solution for peritoneal dialysis The present invention provides a solution for peritoneal dialysis, consisting of at least two single solutions which are combined after a heat sterilization and are administered to a patient, the first single solution containing an osmotic and the second single solution containing a buffer, and one of these single solutions or another single solution containing electrolyte salts. Glucose-like degradation and hydrolysis is avoided during sterilization and storage, while maintenance of a neutral mixture pH is achieved by the osmotic comprising a glucose polymer and/or glucose polymer derivative, and the pH of the first single solution being between 3.5 and 5.0. The present invention further discloses a twin-chambered pouch consisting of a plastic pouch with at least one first chamber and a second chamber, the first single solution being included in the first chamber and the second single solution being included in the second chamber.
US08883760B2	Cancer therapy using beta glucan and antibodies The present invention relates to methods of using neutral soluble glucan and monoclonal antibodies for antitumor therapy. Neutral soluble Beta (1,3; 1,6) glucan (NSG) enhances the tumoricidal activity of the innate immune system by binding to the C3 complement protein receptor CR3. The glucan does not stimulate the induction of inflammatory cytokines. Also described are methods of using whole glucan particles (WGP) as an immunomodulator by inducing a shift from a Th2 response to the Th1 response, leading to an enhanced antitumor cytotoxic T-cell response.
US08883759B2	Anti-tumor effect potentiator There is provided an agent for potentiating the effects of an anti-tumor agent.An anti-tumor effect potentiator containing, as an active ingredient, a uracil compound represented by the following formula (I) or a pharmaceutically acceptable salt thereof: wherein X represents a C1-5 alkylene group and one of methylene groups constituting the alkylene group is optionally substituted with an oxygen atom; R1 represents a hydrogen atom or a C1-6 alkyl group; R2 represents a hydrogen atom or a halogen atom; and R3 represents a C1-6 alkyl group, a C2-6 alkenyl group, a C3-6 cycloalkyl group, a (C3-6 cycloalkyl) C1-6 alkyl group, a halogeno-C1-6 alkyl group or a saturated heterocyclic group.
US08883755B2	Mitochondrial targeted RNA expression system and use thereof Described herein is a mitochondrial-targeted RNA expression system (mtTRES) for delivery of RNA molecules to mitochondria. mtTRES vectors generate RNAs in vivo that are un-capped, non-polyadenylated, and actively directed to mitochondria. The disclosed vectors are capable of delivering either non-coding RNA molecules or RNA molecules encoding a protein of interest to the mitochondria. In particular, the disclosed vectors include (1) an RNAPIII initiation (promoter) sequence, (2) a non-coding leader sequence (NCL), (3) a mitochondrial translation initiation sequence and an ORF encoding a protein of interest, or a sequence encoding a non-coding RNA, and (4) an RNAPIII termination sequence.
US08883752B2	5′ and 2′ BIS-substituted nucleosides and oligomeric compounds prepared therefrom The present invention provides modified nucleosides and oligomeric compounds prepared therefrom. More particularly, the present invention provides modified nucleosides having at least one 5′-substituent and a 2′-O-substituent, oligomeric compounds comprising at least one of these modified nucleosides and methods of using the oligomeric compounds. In some embodiments, the oligomeric compounds provided herein are expected to hybridize to a portion of a target RNA resulting in loss of normal function of the target RNA.
US08883748B2	Formulation for treating fungal infection A novel formulation for treating fungal infections comprising Cholesterol containing Nanosomal Amphotericin B in a Saline Suspension.
US08883745B2	C—glycolipids with enhanced Th-1 profile The invention is directed to novel synthetic C-glycolipids that selectively induce a ThI-type immune response characterized by enhanced IL-12 secretion and increased activation of dendritic cells. The compounds of the invention are thereby useful in treating infections, cancers, cell proliferative disorders, and autoimmune diseases, both directly and as adjuvants.
US08883740B2	Peptides, compositions, and uses thereof Compositions for regenerating tissue and wound repair, among other applications, are described.
US08883736B2	Compositions and methods for treating and diagnosing cancer The present invention relates to compositions and methods for characterizing, diagnosing and treating cancer. In particular, the present invention identifies LGR5 as a protein over-expressed in solid tumor stem cells. The present invention further identifies an interaction between RSPO1 and LGR5 as an alternative pathway for the activation of beta-catenin signaling. In certain embodiments, the present invention provides biomolecules that disrupt functional signaling via a LGR protein, including, in certain embodiments, molecules that inhibit the interaction between one or more RSPO proteins and one or more LGR proteins, such as LGR5. In certain embodiments, the present invention provides methods of treating cancer comprising disrupting functional LGR signaling and inhibiting growth of a solid tumor comprising solid tumor stem cells.
US08883735B2	Low density lipoprotein-related protein 6 (LRP6)-half life extender constructs The present invention relates to LRP6 constructs that bind to LRP6 receptor. The LRP6 constructs comprise at least one LRP6 binding moiety and a half-life extender molecule such that the LRP6 construct inhibit the Wnt signaling pathway without potentiation of the Wnt signal. The LRP6 constructs also have an increased half-life to provide more time for the therapeutic benefit.
US08883732B2	Therapeutic application of adiponectin in patients with ventricular fibrillation A therapeutic method for cardiac diseases such as angina, myocardial infarction, arrhythmia (ventricular tachycardia, ventricular fibrillation and atrial fibrillation) is provided. The method is characterized by intracoronary administration of adiponection to mammals.
US08883729B2	Nanolipoprotein particles and related compositions, methods and systems Functionalized nanolipoprotein particle presenting an anchor substrate compound for binding with a corresponding anchor compound presented on a target molecule, and related compositions methods and systems.
US08883724B2	Active antiangiogenic therapy Application of oligonucleotide and polypeptide sequences of molecules of the family of the vascular permeability factor (VPF), their receptors, and co-receptors, as well as their modifications, in the active immunotherapy of pathologic entities in which course is associated to the increase of angiogenesis.These procedures can be employed in the single or combined therapy for the treatment of cancer and its metastasis, acute and chronic inflammatory processes, infectious diseases, autoimmune diseases, diabetic and newborn retinopathies, organ transplant rejection, macular degeneration, neovascular glaucoma, hemangioma, and angiofibroma, among others.
US08883722B2	Human insulin containing additional disulfide bonds The present invention is related to human insulin containing additional disulfide bonds and methods of making such.
US08883721B2	Methods of inhibiting the ghrelin/growth hormone secretatogue receptor pathway and uses thereof The invention provides methods for treatment, prevention or management of obesity, obesity related disorders, diabetes mellitus, and metabolic syndrome in a subject by administering a ghrelin O-acyltransferase (GOAT) inhibitor and/or a ghrelin receptor antagonist to the subject. The invention also provides ghrelin receptor antagonists of formula (VII): A11-A12-A13-Gly-Ser-A14-Phe-Leu-A15-A16-A17-A18 (SEQ ID NO: 93), wherein each of A11, A12, and A13 is independently absent, an amino acid, or an amino protecting group; each of A15, A16, A17, and A18 is independently absent or an amino acid; and A14 is a serine conjugated with a —(O)C1-C20alky or a diaminopropionic acid conjugated with a —C(O)C1-C20alkyl group, provided that at least one of A11, A12, or A13 is present.
US08883715B2	Biocompatible polymers, process for their preparation and compositions containing them A process for treating fibroses including administering a therapeutically effective amount of a pharmaceutical composition which includes at least one biocompatible polymer of the following general formula (I): AaXxYy wherein: A represents a monomer selected from the group consisting of a sugar or —(O—CH2—CH2—CO)—, X represents a carboxyl group bonded to monomer A, Y represents a sulfate or sulfonate group bonded to monomer A a represents the number of monomers A such that the mass of the polymers of formula (I) is greater than approximately 5,000 da, x represents a substitution rate of the monomers A by the groups X, which is between approximately 20 and 150%, and y represents a substitution rate of the monomers A by the groups Y, which is between approximately 30 and 150%.
US08883713B2	Fabric softener active composition The present invention is directed to compositions that are characterized by the presence of ester quats with specific characteristics that promote dispersibility at low temperature. Among the important characteristics of the ester quats are an iodine value of 65-85 and distribution of: 33-38% monoesters, 50-55% diesters and 7-12% triesters.
US08883712B2	Fabric softening composition A fabric softening composition which comprises as component A a tertiary or quaternary ammonium salt of formulae (I) or (II): R1R2R3N+CH2CHR4OC(═O)R5X− (I) R1R2R3N+(CH2)3NHR(═O)R5X− (II) in which R1 is hydrogen, methyl or ethyl, R2 and R3, independently of one another, are C1-4 alkyl or C2-4 hydroxyalkyl, R4 is hydrogen or methyl, R5 is a linear C15-21 alkyl or alkenyl radical and X− is a monovalent anion, and as component B a nonionic softener with only one long-chain hydrocarbon radical bonded to a polar radical having at least one free hydroxy group, where fatty alcohol alkoxylate or fatty acid alkoxylate are excluded as component B, exhibits a good softening effect and forms storage-stable dispersions if the molar ratio of component A to component B is in the range from 2:1 to 1:3, the difference between the average chain length of the long-chain hydrocarbon radicals of components A and B is at most 2 carbon atoms and the hydrocarbon radicals of components A and B have on average in each case at most 0.5 double bonds per hydrocarbon radical. Such a composition can be produced by reacting a fatty acid, a C2-6 diol or C3-9 polyol, and a tertiary alkanolamine or a diamine having a tertiary and primary amino group in a suitable molar ratio with the removal of water and subsequent alkylation or protonation.
US08883709B2	Laundry pretreatment compositions containing fatty alcohols A liquid composition for treatment of stained fabric is disclosed. The composition may be an aqueous emulsion that includes a fatty alcohol as a stabilizing agent. The composition may also include one or more nonionic surfactants, detersive enzymes, borax, cleaning agents, fragrances, pH adjusting agents, thickeners, and preservatives. The composition may remain a stable emulsion after even long term storage at various temperatures. Moreover, the composition's improved stability is achieved without significantly sacrifice of its stain removal performance.
US08883708B2	Azeotrope-like compositions of tetrafluoropropene and hydrofluorocarbons Provided are azeotrope-like compositions comprising tetrafluoropropene and hydrofluorocarbons and uses thereof, including use in refrigerant compositions, refrigeration systems, blowing agent compositions, and aerosol propellants.
US08883707B2	Azeotrope-like composition of PF5 and HF Provided are azeotropic and azeotrope-like compositions of PF5 and HF, and methods of making such compositions. Such azeotropic and azeotrope-like compositions can be used, for example, in processes for producing LiPF6.
US08883706B2	Anionic micelles with cationic polymeric counterions systems thereof The invention relates to a polymer-micelle complex. The polymer-micelle complexes include a negatively charged micelle that is electrostatically bound to a water-soluble polymer bearing a positive charge. The polymer does not comprise block copolymer, latex particles, polymer nanoparticles, cross-linked polymers, silicone copolymer, fluorosurfactant, or amphoteric copolymer. The compositions do not form a coacervate, and do not form a film when applied to a surface.
US08883704B2	Bleach granules The invention relates to co-granules containing a) at least one bleach activator, b) at least one metal-containing bleach catalyst, and c) at least 5 wt. % of at least one organic acid. The co-granules are easy to produce, have a high stability in storage and are advantageously suitable for producing cleaning products and detergents and especially products for cleaning crockery in a machine.
US08883703B2	Laundry detergent composition comprising particles of phthalocyanine compound encapsulated in low bloom gelatine The present invention relates to encapsulated phthalocyanine particles, to a process for the preparation thereof, compositions comprising such particles and washing agent formulations.The encapsulated phthalocyanine particles comprise a) at least one water-soluble phthalocyanine compound, and b) gelatine having a bloom strength of 2 to 80 as encapsulating material.
US08883701B2	Method for wafer dicing and composition useful thereof A solution for semiconductor wafer dicing is disclosed. The solution suppresses the adherence of contamination residues or particles, and reduces or eliminates the corrosion of the exposed metallization areas, during the process of dicing a wafer by sawing. The solution comprises at least one organic acid and/or salt thereof; at least a surfactant and/or at least a base; and deionized water, the composition has a pH is equal or greater than 4. The solution can further comprise, a chelating agent, a defoaming agent, or a dispersing agent.
US08883699B2	Resist stripping composition and method of stripping resist using the same Disclosed herein is a resist stripping composition, which has an excellent ability of stripping a residual resist remaining after dry or wet etching at the tune of forming patterns in a process of manufacturing a flat panel display substrate.
US08883693B2	Proppant particles formed from slurry droplets and method of use Proppant material for hydraulic fracturing is provided. The particles of the proppant are formed by drip casting. A slurry of finely divided ceramic particles is flowed through nozzles and formed into droplets under the influence of vibration. Uniform sized, smooth surface, spherical green particles are formed. The green particles are dried and sintered to form the proppant. The proppant is used in the process of hydraulic fracturing of wells.
US08883692B2	Method for cell surface displaying of target proteins using Bacillus anthracis exosporium The present invention relates to a method for expressing a target protein on the surface of a microorganism using Bacillus anthracis exosporium protein. More particularly, to an expression vector constructed such that it comprises bclA gene encoding Bacillus anthracis exosporium protein BclA or fragments thereof as a cell surface anchoring motif and the target protein can be expressed on the surface of a cell in a form fused with BclA or a fragment thereof when the gene encoding the target protein is expressed in a host cell, as well as, a method for expressing a target protein on the surface of a microorganism using the vector. The expression vector according to the present invention is capable of effectively expressing a target protein or a peptide on the cell surface using BclA, Bacillus anthracis exosporium protein as a cell surface anchoring motif, and since a target protein can be stably expressed on the cell surface in large amounts by culturing a microorganism transformed with the expression vector, thus making it possible to effectively use for the various purposes of recombinant live vaccines, whole cells absorbents, whole cell bioconversion and the like.
US08883690B2	Superconducting accelerating cavity production method A superconducting accelerating cavity production method with which a high-quality superconducting accelerating cavity can be produced with a compact device configuration and at low cost. The method of producing a superconducting accelerating cavity (1) includes arranging, in an axial direction (L), a plurality of half-cells (5) having openings at both ends in the axial direction and joining the openings to one another by welding. The half-cells (5) are joined by welding with a laser beam from the inside of the superconducting accelerating cavity (1) in which a vacuum atmosphere is created.
US08883687B2	Herbicidal composition Provided is a herbicidal composition comprising a herbicidally active compound selected from a difluoromethanesulfonylanilide compound represented by the general formula (I): wherein R1 represents a hydrogen atom, an alkyl group or an alkoxyalkyl group; or a salt thereof encapsulated in a microcapsule, or a herbicidal composition comprising the herbicidally active compound encapsulated in a microcapsule and a benzoic acid compound represented by the general formula (II): wherein R2 represents a hydrogen atom, an alkyl group having 1 to 15 carbon atoms, a hydroxyl group, a nitro group, or an amino group; and R3 represents a hydrogen atom, an alkali metal atom or an alkyl group. The herbicidal composition exert a pharmacological effect for a prolonged period of time, can alleviate or prevent any harmful effect and can reduce the environmental load.
US08883686B2	Biocide compositions comprising glycerol(ether)phosphates Suggested are biocide compositions, comprising (a) Glycerol(ether)phosphates; (b) Biocides and optionally (c) Oil components or co-solvents and/or (d) Emulsifiers. The compositions show excellent adjuvant and complexing properties.
US08883684B2	Process for treating with a chemical compound a body of water used in aquaculture A process for treating with at least one chemical compound a body of water comprising at least one living organism selected from fish, mollusks, crustaceans and aquatic plants, such process comprising adding the chemical compound to the body of water and agitating the water with an agitation system comprising a pump and at least one submerged outlet equipped with an eductor nozzle.
US08883682B2	Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylic acid or a derivative thereof and auxin transport inhibitors Provided herein are herbicidal composition containing and method of controlling undesirable vegetation utilizing (a) a compound of formula (I): or an agriculturally acceptable salt or ester thereof and (b) an auxin transport inhibitor. Exemplary auxin transport inhibitors include chlorflurenol-methyl, diflufenzopyr, flurenol and naptalam, or an agriculturally acceptable derivative thereof. The methods and compositions described herein provide control of undesirable vegetation, e.g., in rice, cereals, wheat, barley, oats, rye, sorghum, corn or maize, sugarcane, sunflower, oilseed rape, canola, sugar beet, soybean, cotton, pineapple, vegetables, pastures, grasslands, rangelands, fallowland, turf, tree and vine orchards, aquatics, plantation crop, industrial vegetation management (IVM) or rights of way (ROW).
US08883681B2	Sugarcane harvest aid Protoporphyrinogen oxidase enzyme-inhibiting compounds are useful in compositions and methods for ripening sugarcane crops. Of particular interest is the use of carfentrazone ethyl and certain metabolites thereof for ripening sugarcane crops.
US08883678B2	Carrier for ethylene oxide catalysts An improved carrier for an ethylene epoxidation catalyst is provided. The carrier includes an alumina component containing a first portion of alumina particles having a mean primary particle size of, or greater than, 2 μm and up to 6 μm, and a second portion of alumina particles having a particle size less than 2 μm. An improved catalyst containing the above-described carrier, as well as an improved process for the epoxidation of ethylene using the catalyst are also provided.
US08883676B1	Removal of toxic chemicals using metal-organic frameworks (MOFs) post-treated via plasma-enhanced chemical vapor deposition (PECVD) with fluorocarbons A system and method of filtering comprising adsorbing a toxic chemical using a metal-organic framework (MOF) compound that has been post-treated with fluorocarbons using plasma-enhanced chemical vapor deposition (PECVD). The toxic chemical may comprise any of ammonia and cyanogen chloride. Furthermore, the toxic chemical may comprise any of an acidic/acid-forming gas, basic/base-forming gas, oxidizer, reducer, and organic gas/vapor. The toxic chemical is physically adsorbed by the MOF compound. Moreover, the toxic chemical interacts with unsaturated metal sites within the MOF. Additionally, the MOF compound may comprise any of Cu-BTC, MOF-177, and an isoreticular metal-organic framework (IRMOF) compound. The MOF compound may comprise a metal-carboxylate bond. Additionally, the MOF compound may be unstable in the presence of moisture.
US08883671B2	Monolithic catalyst system for the photolysis of water A monolithic catalyst system for the cleavage of water into hydrogen and oxygen comprises a first photoactive material capable by itself or together with an auxiliary material and/or an auxiliary catalyst when irradiated with light having a wavelength≧420 nm of generating oxygen and protons from water, and a second photoactive material capable by itself or together with an auxiliary material and/or an auxiliary catalyst when irradiated with light having a wavelength≧420 nm of reducing protons in water to hydrogen. The first and second photoactive materials are in electrical contact via an electron-conducting material.
US08883670B2	Mo containing catalyst, a preparation method and a method for preparing methyl mercaptan A method is described to prepare a Mo containing supported catalyst comprising TeO2 as active promoter and a process for preparing methanethiol in the presence of said catalyst.
US08883669B2	Hydrocracking catalyst, a process for producing the same, and the use of the same The present invention relates to a hydrocracking catalyst comprising an acidic silica-alumina, an optional alumina, an effective quantity of at least one VIII Group metal component(s), an effective quantity of at least one VIB Group metal component(s) and an organic additive, wherein the organic additive is one or more selected from the group consisting of an oxygen-containing or nitrogen-containing organic compound, and the molar ratio of the organic additive to the VIII Group metal component(s) is 0.01-10. The present invention relates further to a process for producing the hydrocracking catalyst and use of the catalyst in a process for hydrocracking hydrocarbon oils. The hydrocracking catalyst provided according to the present invention shows a higher activity for aromatic hydrosaturating and ring-opening reaction, as compared with the prior art hydrocracking catalyst.
US08883668B2	Phosphorus modified molecular sieves, their use in conversion of organics to olefins The present invention is a phosphorous modified zeolite (A) made by a process comprising in that order: selecting a zeolite with low Si/Al ratio (advantageously lower than 30) among H+ or NH4+-form of MFI, MEL, FER, MOR, clinoptilolite, said zeolite having been made preferably without direct addition of organic template; steaming at a temperature ranging from 400 to 870° C. for 0.01-200 h; leaching with an aqueous acid solution containing the source of P at conditions effective to remove a substantial part of Al from the zeolite and to introduce at least 0.3 wt % of P; separation of the solid from the liquid; an optional washing step or an optional drying step or an optional drying step followed by a washing step; a calcination step. The present invention also relates to a process (hereunder referred as “XTO process”) for making an olefin product from an oxygen-containing, halogenide-containing or sulphur-containing organic feedstock wherein said oxygen-containing, halogenide-containing or sulphur-containing organic feedstock is contacted with the above catalyst (in the XTO reactor) under conditions effective to convert at least a portion of the oxygen-containing, halogenide-containing or sulphur-containing organic feedstock to olefin products (the XTO reactor effluent).The present invention also relates to a process (hereunder referred as “combined XTO and OCP process”) to make light olefins from an oxygen-containing, halogenide-containing or sulphur-containing organic feedstock comprising : contacting said oxygen-containing, halogenide-containing or sulphur-containing organic feedstock in the XTO reactor with the above catalyst at conditions effective to convert at least a portion of the feedstock to form an XTO reactor effluent comprising light olefins and a heavy hydrocarbon fraction; separating said light olefins from said heavy hydrocarbon fraction; contacting said heavy hydrocarbon fraction in the OCP reactor at conditions effective to convert at least a portion of said heavy hydrocarbon fraction to light olefins.
US08883666B2	Process for regenerating catalyst in a fluid catalytic cracking unit One exemplary embodiment can be a process for regenerating catalyst in a fluid catalytic cracking unit. Generally, the process includes providing a feed to a riser of a reaction vessel, and providing a stream to a distributor positioned within a void proximate to an inlet receiving unregenerated catalyst in a regenerator. The feed can include at least one of a gas oil, a vacuum gas oil, an atmospheric gas oil, a coker gas oil, a hydrotreated gas oil, a hydrocracker unconverted oil, and an atmospheric residue.
US08883660B2	Woven preform, composite, and method of making thereof A three dimensional woven preform, a fiber reinforced composite incorporating the preform, and methods of making thereof are disclosed. The woven preform includes two or more warp steered fabrics. The warp steered fabrics include a darted portion and an un-darted portion. The darted portions of the warp steered fabrics are joined to un-darted portions of one another so as to provide continuous fiber in the circumferential and radial directions of all portions of the preform. An un-darted portion in one steered fabric reinforces a darted portion in the other. The warp steered fabrics can be woven on a loom equipped with a differential take-up mechanism. The warp steered fabrics can be single or multilayer fabrics. The final preform can be a portion of an aircraft window frame.
US08883654B2	Method of treating an oxidized layer of metal nitride The present arrangement provides a method of treating an oxidized layer of metal nitride, including oxidizing a layer (2) of metal oxide at the surface of a first layer (1) of nitride of said metal using a plasma of an oxidizing species with an oxidation number that is greater than that of oxygen in order to form a metallic layer (3) of a compound based on said metal; and reducing the metallic layer (3) formed in step i) using a plasma of hydrogen and nitrogen to form a second layer (4) of nitride of said metal.
US08883653B2	Substrate treatment method and substrate treatment apparatus An inventive substrate treatment method includes a silylation step of supplying a silylation agent to a substrate, and an etching step of supplying an etching agent to the substrate after the silylation step. The method may further include a repeating step of repeating a sequence cycle including the silylation step and the etching step a plurality of times. The cycle may further include a rinsing step of supplying a rinse liquid to the substrate after the etching step. The cycle may further include a UV irradiation step of irradiating the substrate with ultraviolet radiation after the etching step. The method may further include a pre-silylation or post-silylation UV irradiation step of irradiating the substrate with the ultraviolet radiation before or after the silylation step.
US08883638B2	Method for manufacturing damascene structure involving dummy via holes A method for manufacturing a damascene structure includes providing a substrate having a dielectric layer formed thereon, forming at least a trench in the dielectric layer, forming at least a via hole and a dummy via hole in the dielectric layer, forming a first conductive layer filling up the trench, the via hole and the dummy via hole on the substrate, and performing a chemical mechanical polishing process to form a damascene structure and simultaneously to remove the dummy via hole.
US08883637B2	Systems and methods for controlling etch selectivity of various materials A method for filling a recessed feature of a substrate includes a) at least partially filling a recessed feature of a substrate with tungsten-containing film using at least one of chemical vapor deposition (CVD) and atomic layer deposition (ALD); b) at a predetermined temperature, using an etchant including activated fluorine species to selectively etch the tungsten-containing film more than an underlying material of the recessed feature without removing all of the tungsten-containing film at a bottom of the recessed feature; and c) filling the recessed feature using at least one of CVD and ALD.
US08883636B2	Process for semiconductor circuit A semiconductor process for forming specific pattern features comprising the steps of forming a target layer, a hard mask layer and a plurality of equally spaced-apart core bodies on a substrate, forming spacers on sidewalls of the core bodies, removing the core bodies so that the spacers are spaced-apart on the hard mask layer, using spacers as a mask to pattern the hard mask layer, removing the hard mask bodies outside of a predetermined region, forming photoresists on several outermost hard mask bodies of the predetermined region, and using the photoresists and remaining hard mask bodies as a mask to pattern the target layer.
US08883635B2	Semiconductor device manufacturing method and semiconductor device manufacturing apparatus A method of manufacturing a semiconductor device includes: preparing a wafer member, the wafer member including a wafer, a conductive layer formed on a surface of the wafer and a negative photoresist formed on the conductive layer; applying a light blocking material so as to cover at least a part of an outer edge of the wafer member from an upper surface of the negative photoresist to a side surface of the negative photoresist; exposing the negative photoresist to exposure light; removing the light blocking material; and developing the negative photoresist.
US08883631B1	Methods of forming conductive structures using a sacrificial material during a metal hard mask removal process One illustrative method disclosed herein includes forming at least one layer of insulating material above a conductive structure, forming a patterned hard mask comprised of metal above the layer of insulating material, performing at least one etching process to define a cavity in the layer of insulating material, forming a layer of sacrificial material so as to overfill the cavity, performing at least one planarization process to remove a portion of the layer of sacrificial material and the patterned hard mask while leaving a remaining portion of the layer of sacrificial material within the cavity, and removing the remaining portion of the layer of sacrificial material positioned within the cavity.
US08883626B2	Interconnection structures and fabrication method thereof A method is provided for fabricating an interconnection structure. The method includes providing a semiconductor substrate having certain semiconductor devices inside, a dielectric layer covering the semiconductor devices, and vias inside the dielectric layer connecting with connection pads of the semiconductor devices. The method also includes forming a first conductive layer on the semiconductor substrate, and forming a second conductive layer with smaller grain sizes by doping the first conductive layer. Further, the method includes forming an interconnection pad by patterning the second conductive layer, and forming a connection wire on the interconnection pad.
US08883625B2	Method for decomposing lines of an electronic circuit A method for defining parallel lines extending along a first direction in a same level of an integrated circuit, among which at least first and second lines separated by an even number of lines are interconnected, a space having a width at least equal to the minimum space between two lines separated by one line being left free, in a second direction perpendicular to the first direction, on either side of a minimum rectangle containing the first and the second lines.
US08883622B2	Method of fabricating and semiconductor memory device using the same A method of fabricating a semiconductor memory device includes preparing a semiconductor substrate which is divided into a cell array region and a core and peripheral region adjacent to the cell array region. Signal lines may be formed in a lower layer in a cell region. An insulation layer may be formed on the lower layer. Signal lines connected to cell region signal lines may be formed on an insulation layer of the peripheral region. A capping layer may be formed on the insulation layer and the core and peripheral signal lines. The capping layer may be etched to expose the lower layer of the cell array region and an etch stop may be formed on the lower layer and the core and peripheral region.
US08883618B2	Method and device for the treatment of a semiconductor substrate Method for the treatment of a semiconductor substrate (2), in which an ion beam (4) is produced from a doping gas and is directed onto the semiconductor substrate (2), characterized in that the doping gas is fed through a plastic hose (6) to a unit (3) for producing an ion beam (4), and is then ionized. The method and the device advantageously permit the supply of the unit 3 for producing an ion beam 4 with a doping gas from customary gas reservoirs 14 such as customary compressed gas cylinders, for example. Voltage flashovers from the deflection elements 5 are effectively prevented by the use of a plastic hose 6. The method and the device thus permit the simple construction of a corresponding ion implantation apparatus in conjunction with possible inexpensive supply thereof with doping gas.
US08883613B2	Manufacturing method of semiconductor device, processing method of semiconductor wafer, semiconductor wafer A disclosed method of manufacturing a semiconductor device includes forming a groove on a first surface of a semiconductor wafer along an outer periphery of the semiconductor wafer, forming a semiconductor device on the first surface, forming an adhesive layer on the first surface to cover the semiconductor device, bonding a support substrate to the first surface by the adhesive layer, grinding after the adhering of the support substrate a second surface of the semiconductor wafer opposite to the first surface, and dicing after the grinding the semiconductor wafer into individual semiconductor chips.
US08883610B2	Microstructure device including a metallization structure with self-aligned air gaps between closely spaced metal lines In sophisticated metallization systems, air gaps may be formed on the basis of a self-aligned patterning regime during which the conductive cap material of metal lines may be protected by providing one or more materials, which may subsequently be removed. Consequently, the etch behavior and the electrical characteristics of metal lines during the self-aligned patterning regime may be individually adjusted.
US08883608B2	Methods of manufacturing a semiconductor device An alignment mark is formed on a substrate including a first region and a second region. The alignment mark is formed in the second region. An etch target layer including a crystalline material is formed on the alignment mark and the substrate. The etch target layer in the first region is partially amorphized. The amorphized etch target layer is etched to form an opening.
US08883605B2	Decoupling composite capacitor in a semiconductor wafer According to an exemplary embodiment, a method for fabricating a decoupling composite capacitor in a wafer that includes a dielectric region overlying a substrate includes forming a through-wafer via in the dielectric region and the substrate. The through-wafer via includes a through-wafer via insulator covering a sidewall and a bottom of a through-wafer via opening and a through-wafer via conductor covering the through-wafer via insulator. The method further includes thinning the substrate, forming a substrate backside insulator, forming an opening in the substrate backside insulator to expose the through-wafer via conductor, and forming a backside conductor on the through-wafer via conductor, such that the substrate backside conductor extends over the substrate backside insulator, thereby forming the decoupling composite capacitor. The substrate forms a first decoupling composite capacitor electrode and the through-wafer via conductor and substrate backside conductor form a second decoupling composite capacitor electrode.
US08883601B2	Method of manufacturing a semiconductor device having a laminated structure comprising a boron-doped silicon germanium film and a metal film A semiconductor device has memory cell portions and compensation capacitance portions on a single substrate. The memory cell portion and the compensation capacitance portion have mutually different planar surface areas. The memory cell portion and the compensation capacitance portion include capacitance plate electrodes of the same structure. The capacitance plate electrode has a laminated structure including a boron-doped silicon germanium film and a metal film.
US08883599B2	2DEG Schottky diode formed in nitride material with a composite Schottky/ohmic electrode structure and method of making the same A method for manufacturing a semiconductor device includes preparing a base substrate; forming a semiconductor layer on the base substrate; forming an ohmic electrode part having ohmic electrode lines, on the semiconductor layer; and forming a Schottky electrode part, which is disposed on the semiconductor layer to be spaced apart from the ohmic electrode lines and has Schottky electrode lines parallel to the ohmic electrode lines, wherein forming the ohmic electrode part further comprises forming an ohmic electrode plate connected to one end of the ohmic electrode lines, forming the Schottky electrode part further comprises forming a Schottky electrode plate connected one end of the Schottky electrode lines, and one line of the Schottky electrode lines is disposed between two of the ohmic electrode lines to thereby achieve an interdigited configuration in which the ohmic electrode part and the Schottky electrode part are formed.
US08883598B2	Thin capped channel layers of semiconductor devices and methods of forming the same Semiconductor devices and methods of forming the same. The method includes providing a semiconductor substrate having a channel layer over the substrate. A capping layer including silicon and having a first thickness is formed over the channel layer. The capping layer is partially oxidized to form an oxidized portion of the capping layer. The oxidized portion of the capping layer is removed to form a thinned capping layer having a second thickness less than the first thickness.
US08883597B2	Method of fabrication of a FinFET element The present disclosure provides a method of fabricating a FinFET element including providing a substrate including a first fin and a second fin. A first layer is formed on the first fin. The first layer comprises a dopant of a first type. A dopant of a second type is provided to the second fin. High temperature processing of the substrate is performed on the substrate including the formed first layer and the dopant of the second type.
US08883596B2	Semiconductor device with vertical channel transistor and method of fabricating the same A semiconductor device with vertical channel transistors and a method of fabricating the same are provided. A method of fabricating the semiconductor device includes patterning a substrate to form a trench that defines an active region, forming a sacrificial pattern in a lower region of the trench, forming a spacer on an upper sidewall of the trench, recessing a top surface of the sacrificial pattern to form a window exposing a sidewall of the active region between the spacer and the sacrificial pattern, doping a sidewall of the trench through the window to form a doped region in the active region, and forming a wiring in the trench to be connected to the doped region.
US08883593B2	Method of manufacturing a pillar-type vertical transistor A semiconductor pillar which has a first conductivity type and protrudes from a semiconductor substrate, is formed. A bottom diffusion layer having a second conductivity type is formed in the semiconductor substrate around a bottom of the semiconductor pillar. A gate insulator film which covers a side surface of the semiconductor pillar, is formed. A gate electrode which covers the gate insulator film, is formed. A top diffusion layer having the second conductivity type is formed at a top portion of the semiconductor pillar. The top diffusion layer including a semiconductor body is formed by an epitaxial growth which contains an impurity.
US08883591B2	Method for obtaining extreme selectivity of metal nitrides and metal oxides Methods for etching metal nitrides and metal oxides include using ultradilute HF solutions and buffered, low-pH HF solutions containing a minimal amount of the hydrofluoric acid species H2F2. The etchant can be used to selectively remove metal nitride layers relative to doped or undoped oxides, tungsten, polysilicon, and titanium nitride. A method is provided for producing an isolated capacitor, which can be used in a dynamic random access memory cell array, on a substrate using sacrificial layers selectively removed to expose outer surfaces of the bottom electrode.
US08883589B2	Counter doping compensation methods to improve diode performance A method of forming a memory cell is provided, the method including forming a diode including a first region having a first conductivity type, counter-doping the diode to change the first region to a second conductivity type, and forming a memory element coupled in series with the diode. Other aspects are also provided.
US08883588B2	Semiconductor devices and methods of manufacturing the semiconductor devices A method of manufacturing a semiconductor device, the method including forming a tunnel insulating layer on an upper surface of a substrate, forming gate patterns on an upper surface of the tunnel insulating layer, forming capping layer patterns on sidewalls of the gate patterns and on the upper surface of the tunnel insulating layer, etching a portion of the tunnel insulating layer that is not covered with the gate patterns or the capping layer patterns to form a tunnel insulating layer pattern, and forming a first insulating layer on the upper surface of the substrate to cover the gate patterns, the capping layer patterns, and the tunnel insulating layer pattern, wherein the first insulating layer has an air gap between the capping layer patterns.
US08883587B2	Method of manufacturing semiconductor device A method of manufacturing a semiconductor device includes forming silicon line patterns in a semiconductor substrate, forming an insulating layer over the silicon line patterns, forming a conductive pattern between the silicon line patterns, forming a spacer over the substrate, forming an interlayer insulating layer between the silicon line patterns, removing the spacer on one side of the silicon line patterns to expose the conductive pattern, forming a bit line contact open region by removing the interlayer insulating layer, forming a polysilicon pattern to cover the bit line contact open region, and forming a junction region diffused to the silicon line pattern through the bit line contact open region. Thereby, a stacked structure of a titanium layer and a polysilicon layer are stably formed when forming a buried bit line and a bit line contact is formed using diffusion of the polysilicon layer to prevent leakage current.
US08883576B2	Methods of fabricating semiconductor devices using mask shrinking Provided are methods of fabricating a semiconductor device. The method may include forming a mold layer on a substrate, forming a mask layer on the mold layer, etching the mold layer using the mask layer as an etch mask to form a channel hole penetrating the mold layer, shrinking the mask layer to provide a reduced mask layer, forming a spacer layer to cover the reduced mask layer, and forming a vertical channel to fill the channel hole and be electrically connected to the substrate. As a result, the channel hole can have an enlarged entrance.
US08883575B2	Processes and apparatus having a semiconductor fin A process may include forming a mask directly on and above a region selected as an initial semiconductor fin on a substrate and reducing the initial semiconductor fin forming a semiconductor fin that is laterally thinned from the initial semiconductor fin. The process may be carried out causing the mask to recede to a greater degree in the lateral direction than the vertical direction. In various embodiments, the process may include removing material from the fin semiconductor to achieve a thinned semiconductor fin, which has receded beneath the shadow of the laterally receded mask. Electronic devices may include the thinned semiconductor fin as part of a semiconductor device.
US08883570B2	Multi-gate FETs and methods for forming the same A method includes oxidizing a semiconductor fin to form an oxide layer on opposite sidewalls of the semiconductor fin. The semiconductor fin is over a top surface of an isolation region. After the oxidizing, a tilt implantation is performed to implant an impurity into the semiconductor fin. The oxide layer is removed after the tilt implantation.
US08883569B2	Continuous mesh three dimensional non-volatile storage with vertical select devices A three-dimensional array adapted for memory elements that reversibly change a level of electrical conductance in response to a voltage difference being applied across them. Memory elements are formed across a plurality of planes positioned different distances above a semiconductor substrate. Bit lines to which the memory elements of all planes are connected are oriented vertically from the substrate and through the plurality of planes.
US08883567B2	Process of making a stacked semiconductor package having a clip A method of making a stacked semiconductor package having at least a leadframe, a first die mounted above and soldered to the lead frame and a first clip mounted above and soldered to the first die. The method includes positioning the leadframe, first die and first clip in a vertically stacked relationship and nonsolderingly locking the first clip in laterally nondisplaceble relationship with the leadframe. A stacked semiconductor package and an intermediate product produced in making a stacked semiconductor package are also disclosed.
US08883562B2	Reconstituted wafer stack packaging with after-applied pad extensions A stacked microelectronic unit is provided which can include a plurality of vertically stacked microelectronic elements each having a front surface, contacts exposed at the front surface, a rear surface and edges extending between the front and rear surfaces. Traces connected with the contacts may extend along the front surfaces towards edges of the microelectronic elements with the rear surface of at least one of the stacked microelectronic elements being adjacent to a top face of the microelectronic unit. A plurality of conductors may extend along edges of the microelectronic elements from the traces to the top face. The conductors may be conductively connected with unit contacts such that the unit contacts overlie the rear surface of the at least one microelectronic element adjacent to the top face.
US08883560B2	Manufacturing of a device including a semiconductor chip A method includes providing a semiconductor chip having a first main surface and a second main surface opposite to the first main surface. An electrically insulating material is deposited on the first main surface of the semiconductor chip using a plasma deposition method. A first electrically conductive material is deposited on the second main surface of the semiconductor chip using a plasma deposition method.
US08883557B1	Controlling composition of multiple oxides in resistive switching layers using atomic layer deposition A method of fabricating a resistive random access memory (ReRAM) cell may include forming a set of nanolaminate structures over an electrode, such that each structure includes at least one first element oxide layer and at least one second element oxide layer. The overall set is operable as a resistive switching layer in a ReRAM cell. In this set, an average atomic ratio of the first element to the second element is different in at least two nanolaminate structures. This ratio may be less in nanolaminate structures that are closer to electrodes than in the middle nanolaminate structures. Alternatively, this ratio may increase from one end of the set to another. The first element may be less electronegative than the second elements. The first element may be hafnium, while the second element may be one of zirconium, aluminum, titanium, tantalum, or silicon.
US08883556B2	Semiconductor device and manufacturing method thereof A semiconductor device capable of high speed operation is provided. Further, a semiconductor device in which change in electric characteristics due to a short channel effect is hardly caused is provided. An oxide semiconductor having crystallinity is used for a semiconductor layer of a transistor. A channel formation region, a source region, and a drain region are formed in the semiconductor layer. The source region and the drain region are formed by self-aligned process in which one or more elements selected from Group 15 elements are added to the semiconductor layer with the use of a gate electrode as a mask. The source region and the drain region can have a wurtzite crystal structure.
US08883553B2	Independently controlled stacked inverted organic light emitting diodes and a method of manufacturing same An OLED apparatus is provided that includes a first electrode having a first polarity, and an electrode arrangement spaced apart from the first electrode and having a second polarity. The OLED apparatus also includes a first organic emissive layer interposed between the first electrode and the electrode arrangement, and a second electrode spaced apart from the electrode arrangement in a direction opposite the first electrode. The second electrode has the first polarity. The OLED apparatus further includes a second organic emissive layer interposed between the second electrode and the electrode arrangement, and a drive circuit for providing a first energizing signal to the first electrode and the electrode arrangement and a second energizing signal to the second electrode and the electrode arrangement. A method for manufacturing an OLED array is provided.
US08883552B2	MWT architecture for thin SI solar cells Methods of fabricating metal wrap through solar cells and modules for thin silicon solar cells, including epitaxial silicon solar cells, are described. These metal wrap through solar cells have a planar back contact geometry for the base and emitter contacts. Fabrication of a metal wrap through solar cell may comprise: providing a photovoltaic device attached at the emitter side of the device to a solar glass by an encapsulant, the device including busbars on the device emitter; forming vias through the device base and emitter, the vias terminating in the busbars; depositing a conformal dielectric film over the surface of the vias and the back surface of the base; removing portions of the conformal dielectric film from the ends of the vias for exposing the busbars and from field areas of the base; and forming separate electrical contacts to the busbars and the field areas on the back surface of the solar cell. The solar cells may comprise epitaxially deposited silicon and may include an epitaxially deposited back surface field.
US08883549B2	p-Doping of CdTe polycrystalline thin film based on Cd vacancy theory Exemplary embodiments of the present disclosure are directed to improve p-type doping (p-doping) of cadmium telluride (CdTe) for CdTe-based solar cells, such as cadmium Sulfide (Cds)/CdTe solar cells. Embodiments can achieve improved p-doping of CdTe by creating a high density of cadmium (Cd) vacancies (VCd) and subsequently substituting a high density of substitutional defects and/or defect complexes for the Cd vacancies that were created. Formation of a high density of substitutional defects and defect complexes as a p-dopant can improve light-to-electricity conversion efficiency, doping levels or hole concentrations, junction band bending, and/or ohmic contact associated with p-type CdTe (p-CdTe) based solar cells.
US08883548B2	Development of an electronic device quality aluminum antimonide (AlSb) semiconductor for solar cell applications Electronic device quality Aluminum Antimonide (AlSb)-based single crystals produced by controlled atmospheric annealing are utilized in various configurations for solar cell applications. Like that of a GaAs-based solar cell devices, the AlSb-based solar cell devices as disclosed herein provides direct conversion of solar energy to electrical power.
US08883545B2	Method and device for producing a solar panel using a carrier The invention relates to the production of solar panels which comprise solar cells connected to one another. In this case, various layers are stacked onto one another, such as a film layer, bonding agent, insulating film, solar cells and a support layer. Combining all these layers to form the final panel is carried out on a carrier which stabilizes and supports the stack while it is conveyed past the various treatment stations. The turning over of the stack can also be carried out in a reliable manner by means of such a carrier without shifts between the various components with respect to one another occurring.
US08883543B2	Method of producing wafer for solar cell, method of producing solar cell, and method of producing solar cell module Provided is a method of producing a wafer for a solar cell that can produce the solar cell with high conversion efficiency.A method of producing a wafer for a solar cell according to the present invention comprises a first step of contacting lower alcohol to at least one surface of the semiconductor wafer and a second step, after the first step, of contacting hydrofluoric acid containing metal ion to the at least one surface of the semiconductor wafer, and a third step that is, after the second step, a step of contacting alkali solution to the at least one surface of the semiconductor wafer, a step of contacting acid solution containing hydrofluoric acid and nitric acid to the at least one surface of the semiconductor wafer, or a step of carrying out an oxidation treatment to the at least one surface of the semiconductor wafer.
US08883542B2	Solid-state imaging device, production method and drive method thereof, and camera A solid-state imaging device capable of reducing an eclipse (blocking) of an incident light at a circumferential portion of a light receiving portion and realizing a larger angle of view and high-speed driving. A single-layer transfer electrode configuration of forming first transfer electrodes and second transfer electrodes by one polysilicon layer is adopted. Two shunt wirings extending in a horizontal direction are formed on the first transfer electrodes connected in a horizontal direction and, for example, four-phase transfer pulses are supplied to first transfer electrodes and second transfer electrodes on transfer channels through low-resistance shunt wirings extending in the horizontal direction.
US08883541B2	Self-powered integrated circuit with multi-junction photovoltaic cell A photovoltaic cell is provided as a composite unit together with elements of an integrated circuit on a common substrate. In a described embodiment, connections are established between a multiple photovoltaic cell portion and a circuitry portion of an integrated structure to enable self-powering of the circuitry portion by the multiple photovoltaic cell portion.
US08883539B2	Solar cell and method of its manufacture The invention relates to a solar cell (1) comprising an emitter layer (11) at a front side (10) and a base layer (12) at the rear side (20). The solar collects first charge carriers at the front side (10) and second charge carriers at the rear side (20). The solar cell (1) further comprises at least one collecting point (14′) provided at the rear side (20) and a corresponding electrical conducting path to guide the first charge carriers from the front side (10) to the at least one collecting point (14′). An insulating layer (40) is provided between at least part of the electrical conducting path and the base layer (12) to provide electrical insulation between the electrical conductive path and the base layer (12).
US08883537B2	Photoelectric conversion device and method for manufacturing the same A circuit layer is formed on a surface of a substrate and includes a transistor. A photoelectric conversion element includes a photoelectric conversion layer of a chalcopyrite-type semiconductor provided between a first electrode and a second electrode. A supply layer is formed between the circuit layer and the photoelectric conversion layer and contains an Ia group element. Diffusion of the Ia group element to the photoelectric conversion layer improves the photoelectric conversion efficiency. A protective layer is formed between the supply layer and the circuit layer and prevents the diffusion of the Ia group element to the circuit layer.
US08883531B2	Organic light emitting diode display device and method of manufacturing the same An OLED display device is provided. The OLED display device includes a substrate segmented into a plurality sub-pixel regions, a thin film transistor formed in each of the sub-pixel regions, an insulating layer and a planarization layer formed on the thin film transistor, a semitransparent reflective layer selectively formed in each sub-pixel region on the planarization layer, a protective layer formed on the semitransparent reflective layer, an anode electrode formed in a region corresponding to the semitransparent reflective layer on the protective layer and connected to the thin film transistor, an organic light emitting layer connected to the anode electrode, and emitting light, and a cathode electrode formed on the organic light emitting layer.
US08883530B2	Device manufacturing method and organic EL device A device manufacturing method including substrate preparation, pixel electrode formation, photosensitive film formation, first part exposure, second part exposure, and development. In first part exposure, after execution of photosensitive film formation, first photomask is arranged to face substrate and exposure is performed to cause first part of photosensitive film to be exposed to light via first photomask. In second part exposure, after or together with execution of first part exposure, second photomask is arranged to face substrate and exposure is performed to cause second part of photosensitive film, which is different from first part at least partially, to be exposed to light via second photomask. In second part exposure, second photomask is arranged such that end thereof overlaps with end of first photomask, and overlap between first and second photomasks positionally corresponds to electrical wire.
US08883529B2	Method for manufacturing semiconductor light emitting device A semiconductor light emitting device having high reliability and excellent light distribution characteristics can be provided with an n-electrode arranged on a light extraction surface on the side opposite to the surface whereupon a semiconductor stack is mounted on a substrate. A plurality of convexes are arranged on a first convex region and a second convex region on the light extraction surface. The second convex region adjoins the interface between the n-electrode and the semiconductor stack, between the first convex region and the n-electrode. The base end of the first convex arranged in the first convex region is positioned closer to a light emitting layer than the interface between the n-electrode and the semiconductor stack, and the base end of the second convex arranged in the second convex region is positioned closer to the interface between the n-electrode and the semiconductor stack than the base end of the first convex.
US08883527B2	Organic light-emitting diode display panel and manufacturing method for the same The present invention discloses an OLED display panel which includes a first TFT array substrate, a first cover and a structural stiffening glue. A first frit and a second frit of the first cover have the structural stiffening glue provided at an outer side thereof, and the structural stiffening glue is in contact with the first TFT array substrate and the first cover. The present invention further discloses a method for manufacturing the OLED display panel. The present invention enables more solid and stable for a structure of the OLED display panel.
US08883526B2	Image pickup device, its control method, and camera An image pickup device, wherein a part of the carriers overflowing from the photoelectric conversion unit for a period of photoelectrically generating and accumulating the carriers may be flowed into the floating diffusion region, and a pixel signal generating unit generating a pixel signal according to the carriers stored in the photoelectric conversion unit and the carriers having overflowed into the floating diffusion region, is provided. The expansion of a dynamic range and the improvement of an image quality can be provided by controlling a ratio of the carriers flowing into the floating diffusion region to the carriers overflowing from such a photoelectric conversion unit at high accuracy.
US08883521B2	Control method of multi-chip package memory device A control method of a multi-chip package memory device includes the steps of applying stack signals to stack pads of memory dies, applying a repair signal to repair pads of the respective memory dies, setting one or more repaired memory dies for replacing a failed memory die among the memory dies, based on the repair signal applied to the respective memory dies, and setting stack states indicating a logical access order of the other memory dies excluding the repaired memory die, based on the stack signals applied to the other memory dies.
US08883513B2	Droplet-based particle sorting The present invention relates to droplet-based particle sorting. According to one embodiment, a droplet microactuator is provided and includes: (a) a suspension of particles; and (b) electrodes arranged for conducting droplet operations using droplets comprising particles. A method of transporting a particle is also provided, wherein the method includes providing a droplet comprising the particle and transporting the droplet on a droplet microactuator.
US08883512B1	Method for diagnosing gestational diabetes, preeclampsia, and fetal growth restriction A serum-based biomarker for diagnosing gestational diabetes, preeclampsia and fetal growth restriction (GDM-PREEC-FGR), based on retinoid profiling, and a method for diagnosing GDM-PREEC-FGR that specifically uses a blood sample to identify and measure the concentrations of retinol (vitamin A alcohol), retinyl esters and retinoic acid.
US08883510B2	Thrombocyte function determination method using a resonator The invention relates to a method for determining haemostasis parameters by measuring vibration parameters of a resonator having a measuring surface which contacts a platelet containing sample fluid. The invention is characterized by the analysis of the characteristic of a vibration parameter over time, based on which the platelet function will then be assessed and a distinction will be made between the presence of an adhesion disorder or that of an aggregation disorder.
US08883509B2	Apparatus and method for biological sample processing An apparatus and method are described that achieve independent and simultaneous processing of a plurality of substrate-supported biological samples. In one embodiment, substrate holders arranged in a minor arc are independently moveable between a processing position and an access position, and reagents are delivered to substrates held in the substrate holders through a nozzle plate that moves along the arc of substrate holders. The disclosed apparatus and method are particularly suited for implementation of lean processing of biological samples.
US08883495B2	Human T-cell population The present invention has objects to provide a novel human T-cell population having both cytotoxic and immunosuppressive activities, and to a method for preparing the same. The above objects are attained by providing a human T-cell population which is obtainable by coculturing mononuclear cells, collected from human blood, with stroma cells and which has the following features: (1) being positive for CD3, CD25, CD28 and T-cell antigen receptor αβ; (2) essentially consisting of three groups of a CD4 positive and CD8 positive (CD4+CD8+) T-cell group, a CD4 positive and CD8 dimly positive (CD4+CD8dim) T-cell group, and a CD4 negative and CD8 positive (CD4−CD8+) T-cell group; (3) exerting a cytotoxic activity against the cocultured stroma cells; and (4) exerting an immunosuppressive activity against activated T cells.
US08883493B2	Adenoviral vector comprising herpes simplex virus type 1 thymidine kinase and a transgene for increasing the expression of the transgene Compositions and methods useful in transgene expression are provided. Herpes simplex virus type 1 thymidine kinase sequences (“TK sequences”) are used to enhance transgene expression in first generation and high capacity adenoviral vectors. An mCMV promoter-driven β-galactosidase-expressing cassette is combined with TK sequences through direct fusion of the cDNA's. β-galactosidase (transgene) expression is enhanced independent of adenoviral vector selection. Methods of enhancing transgene expression employing the inventive adenoviral vectors are provided, along with pharmaceutical preparations comprising the inventive vectors and kits for enhanced transgene expression.
US08883489B2	Sample testing apparatus and method Apparatus for performing an assay to detect the presence of an analyte in a test sample. A housing defines a slot for receiving a sample collector, and a capsule contains a buffer liquid, the capsule being sealed by an openable lid, and being connected to the housing such that insertion of a sample collector into the slot causes the lid to open releasing the buffer liquid into the slot. The housing further defines an incubation chamber containing or configured to receive a reagent, and an aperture permitting liquid communication between said slot and the incubation chamber. The apparatus comprises one or more test elements, a substantially liquid tight sealing member separating the incubation chamber and the test element(s), and an activation mechanism operable to open said liquid tight sealing member thereby bringing at least a portion of the or each test element into liquid communication with said incubation chamber.
US08883484B2	Method and system for processing organic matter in a poultry farm The invention provides a method and system for processing organic matter that is produced in a poultry farm. The organic matter produced by the plurality of birds is removed from one or more containers that house the plurality of birds. The method further includes treating a first amount of organic matter of the organic matter in a thermal processor to produce inorganic matter. Thereafter, the inorganic matter and a second amount of organic matter of the organic matter are consumed in one or more photo bioreactors for growing one or more photosynthesis organisms.
US08883483B2	Combinatorial DNA library for producing modified N-glycans in lower eukaryotes The present invention relates to eukaryotic host cells having modified oligosaccharides which may be modified further by heterologous expression of a set of glycosyltransferases, sugar transporters and mannosidases to become host-strains for the production of mammalian, e.g., human therapeutic glycoproteins. The invention provides nucleic acid molecules and combinatorial libraries which can be used to successfully target and express mammalian enzymatic activities such as those involved in glycosylation to intracellular compartments in a eukaryotic host cell. The process provides an engineered host cell which can be used to express and target any desirable gene(s) involved in glycosylation. Host cells with modified oligosaccharides are created or selected. N-glycans made in the engineered host cells have a Man5GlcNAc2 core structure which may then be modified further by heterologous expression of one or more enzymes, e.g., glycosyltransferases, sugar transporters and mannosidases, to yield human-like glycoproteins. For the production of therapeutic proteins, this method may be adapted to engineer cell lines in which any desired glycosylation structure may be obtained.
US08883482B2	Methods for increasing homologous recombination of a nucleic acid sequence The present invention relates to methods for increasing homologous recombination of a nucleic acid sequence introduced into a host cell, comprising: (a) introducing into a population of filamentous fungal host cells a first nucleic acid sequence encoding a recombination protein and a second nucleic acid sequence comprising one or more regions which are homologous with the genome of the filamentous fungal host cell, wherein (i) the recombination protein promotes the recombination of the one or more regions with the corresponding homologous region in the host's genome to incorporate the second nucleic acid sequence by homologous recombination, and (ii) the number of host cells comprising the incorporated second nucleic acid sequence in the population is increased at least 20% compared to the same population without the first nucleic acid sequence; (b) and isolating from the population a filamentous fungal cell comprising the incorporated second nucleic acid sequence.
US08883480B2	Antiviral peptide against avian influenza virus H9N2 The present invention relates to recombinant phages carrying fusion peptides that bind to avian influenza virus (AIV). Such phages are useful as diagnostic reagents to replace anti-AIV antibodies because the phages are capable of competing with the latter antibodies for binding sites on the virus. Synthetic peptides with the sequence CNDFRSKTC, either in linear or cyclic conformations, or fusion phages bearing the above said peptides inhibited AIV propagation in embryonated egg as well as in MDCK cell lines. Therefore they may be used as'therapeutic agents to control, to treat and to eradicate bird flu caused by avian influenza virus.
US08883479B2	Method for production of pH stable enveloped viruses The present invention provides a method for producing pH-stable enveloped viruses wherein said viruses are used for infection of host cells under low pH conditions and for incubation with cell culture cells under conditions of low pH, as well as influenza viruses obtainable by this method which exhibit a high growth rate in cell culture, increased pH and temperature stability and which have human receptor specificity.
US08883473B2	Methods of treatment using allosteric processing inhibitors for matrix metalloproteinases The present invention includes a crystal comprising a complex of the pro form of a matrix metalloprotease (proMMP) and a small-molecule allosteric processing inhibitor that inhibits that activation of the proMMP, methods for identifying small-molecule allosteric processing inhibitors that inhibit the activation of a proMMP, and methods of treatment using small-molecule allosteric processing inhibitors that inhibit the activation of a proMMP. The present invention relates to the crystal structure of a complex of proMMP9 bound to a small-molecule allosteric processing inhibitor that inhibits activation of proMMP9. The invention further relates to the use of the methods and the crystal and related structural information for designing, selecting and/or optimizing small-molecule allosteric processing inhibitors that inhibit activation of proMMP9 and proMMP9 homologues. The present invention also relates to the use of small-molecule allosteric processing inhibitors for the treatment of diseases mediated by inappropriate matrix metalloproteinase (MMP) activity.
US08883470B2	Fermentation of carbohydrate A high yield method for fermenting carbohydrate to ethanol, comprising a) treating carbohydrate with a composition containing 10-90 wt % of an aldehyde selected from the group consisting of an formaldehyde, para-formaldehyde, glutaraldehyde and mixtures thereof, 1-50 wt % of a surfactant having an I JLB from 4 to 18, 0-20 wt % of an antimicrobial terpene, or essential oils, 1-50 wt % of organic acids selected from C1-24 fatty acids, their salts, and glyceride esters thereof, and 1-50 wt % water, b) fermenting said carbohydrate in the presence of yeast in a fermentation broth, and c) isolating ethanol in a higher yield than would be obtained without step a).
US08883467B2	Production of fatty alcohols with fatty alcohol forming acyl-CoA reductases (FAR) The disclosure relates to methods of producing fatty alcohols from recombinant host cells comprising genes encoding heterologous fatty acyl-CoA reductase (FAR) enzymes. The disclosure further relates to FAR enzymes and functional fragments thereof derived from marine bacterium and particularly marine gamma proteobacterium such as Marinobacter and Oceanobacter; polynucleotides encoding the FAR enzymes and vectors and host cells comprising the same.
US08883465B2	Enzyme-containing mini-emulsions The present invention relates to a mini-emulsion which comprises at least one hydrolase, where the continuous phase of the mini-emulsion contains at least one oxidant, while the dispersed phase comprises at least one C6-60 carboxylic acid and optionally at least one reactant. Furthermore, the present invention relates to a method of preparing the mini-emulsion and to a process for the preparation of C6-60 percarboxylic acids and to a process for the preparation of an oxidized reactant, in each case using the abovementioned mini-emulsions.
US08883457B2	Compositions and methods for grain processing without pH adjustment Described are compositions and methods relating to starch processing without a phytase pretreatment step and without adjustment of the slurry pH adjustment.
US08883456B2	Processes of producing a fermentation product The invention relates to a process of process of producing a fermentation product, comprising: liquefying a starch-containing material to dextrins with an alpha-amylase in the presence of a GH61 polypeptide; saccharifying the dextrins to a sugar with a glucoamylase; and fermenting the sugar using a fermenting organism.
US08883455B2	Method for detecting the presence of a nucleic acid in a sample An automated method for detecting the presence of a nucleic acid in a sample, where the method is performed within a housing of a self-contained, stand-alone analyzer. The method includes purifying the nucleic acid after it has been immobilized on a magnetically-responsive solid support. A pipette of the analyzer is used to form a reaction mixture comprising the purified nucleic acid and all reagents required to perform a nucleic acid amplification. Amplification products are synthesized that include a nucleotide sequence contained in the nucleic acid or the complement of the nucleic acid. The amplification products are exposed to a probe in a mixture, where the probe forms a hybrid with one of the amplification products. The formation of the hybrid in the mixture provides an indication of the presence of the nucleic acid in the sample.
US08883451B2	Enhanced soluble C5 saccharide yields Methods are disclosed for increasing the level of soluble C5 saccharides produced from lignocellulosic biomass comprising acidifying fractionated lignocellulosic biomass to prevent the recondensation of soluble C5 saccharides, including C5 oligosaccharides and xylose and arabinose monomers, to insoluble higher molecular weight C5 oligosaccharides.
US08883440B2	Method to predict or diagnose a gastrointestinal disorder or disease The disclosure provides methods and compositions useful for identifying a subject's predisposition to a gastrointestinal disease or disorder.
US08883439B2	Blood component measurement method utilizing hemolyzed whole blood, and kit for the method The invention is a method for determining the concentration of an analyte in whole blood, wherein the analyte is a component which is contained in the blood, is different from a component occurring only in a red blood cell, and can generate hydrogen peroxide upon the reaction with an oxidase. Whole blood is utilized in the method. The method comprises the steps of hemolyzing the whole blood and detecting hydrogen peroxide generated by the reaction between the analyte and the oxidase. The measurement method can avoid the inhibition of color development by hemoglobin and the interference with the measurement by hemoglobin. Further it can be used for biological tests that are carried out in a household, an individual doctor's clinic or at the bedside of patients without the need for any blood cell separation procedure or the like, because the measurement utilizes whole blood.
US08883436B2	Method of analyzing cellulose decay in lignocellulosic material hydrolysis Enzymes and/or polypeptides and/or mixtures of interest are evaluated during hydrolysis of cellulosic material by the use of indicator constituents such as fluorescent agents, resulting in efficient high-throughput analysis of enzymes and/or polypeptides. A high-throughput assay for the analysis of inter alia, pretreated corn stover (PCS) hydrolysis is also disclosed.
US08883435B2	Inhibitors of Bruton's tyrosine kinase Described herein are irreversible kinase inhibitor compounds, methods for synthesizing such irreversible inhibitors, and methods for using such irreversible inhibitors in the treatment of diseases. Further described herein are methods, assays and systems for determining an appropriate irreversible inhibitor of a protein, including a kinase.
US08883428B2	Methods to determine atherosclerosis regression, plaque stabilization and cardiovascular risk Provided herein are compositions and methods for examining the progression, regression or risk of individuals at risk for developing coronary artery disease (CAD).
US08883427B2	Quantifying local inflammatory activity and its use to predict disease progression and tailor treatments This invention relates to a method of predicting progression of an inflammatory condition in a subject, which involves providing a medium comprising hyaluronan or a fragment thereof; contacting the medium with a fluid sample from a subject with an inflammatory condition, where the fluid sample comprises proteins or proteoglycans and a transfer agent; incubating the fluid sample with the medium under conditions effective for the transfer agent in the fluid sample to mediate transfer of heavy chains from the proteins or proteoglycans to the hyaluronan or a fragment thereof to form a complex; detecting, using an antibody, occurrence levels of the complex; and comparing occurrence levels of the complex from said detecting to a reference standard to predict progression of an inflammatory condition in the subject. Also disclosed are methods of tailoring treatment of an inflammatory condition and quantifying local inflammatory activity in a body fluid.
US08883426B2	Use of therapeutically effective lipids and method for producing organ-/tissue-specific therapeutically effective lipids The use of therapeutically active lipids for organ/tissue-specific enrichment for the treatment of inflammatory, ischemic or degenerative disorders and/or for stimulating a regeneration is arranged and developed such that the lipids are bound on application to carrier molecules for which cell-specific uptake systems in the cells of the organs and/or tissue exist. In addition, a method of producing organ/tissue-specific therapeutically active lipids for treatment of inflammatory, ischemic or degenerative disorders and/or stimulation of a regeneration, in particular for treating inflammatory liver disorders, is claimed, which is arranged and developed such that lysophosphatidylethanolamine (LysoPE) is coupled to the carboxyl group of ursodeoxycholate (UrsoDOCA) converted to an ester to give a LysoPE-DOCA compound.
US08883425B2	Methods, agents, and compound screening assays for inducing differentiation of undifferentiated mammalian cells into osteoblasts The present invention relates to methods, agents and compound screening assays for inducing differentiation of undifferentiated mammalian cells into osteoblasts. The invention thus provides a method, comprising contacting a compound with a polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID No: 194-309; and measuring a compound-polypeptide property related to the differentiation of said cells. The invention further relates to a bone formation enhancing pharmaceutical composition, and the use thereof in treating and/or preventing a disease involving a systemic or local decrease in mean bone density in a subject. Furthermore, the invention relates to a method for the in vitro production of bone tissue.
US08883421B2	Method for reducing adapter-dimer formation Methods are provided for ligating a 3′ adapter and a 5′ adapter to a target polynucleotide so as to avoid adapter dimer formation. Embodiments of the methods include adding a blocking oligonucleotide after the first ligation in which a 3′ adapter is ligated to the target polynucleotide so that the blocking oligonucleotide is capable of hybridizing to excess 3′ adapter and the ligated 3′ adapter. Subsequently, a 5′ adapter is ligated to the target polynucleotide thus avoiding adapter dimer formation.
US08883419B2	Methods and kits useful for the identification of astrocytoma, it's grades and glioblastoma prognosis The present invention relates to novel primers for identification of astrocytoma, it's grades and glioblastoma prognosis. Further, disclosed is a method of diagnosing the presence of different grades of diffuse astrocytoma and glioblastoma, in a human subject, which involves detection of the expression levels of said genes in tumor tissue samples in comparison to normal brain. Also disclosed is a method of distinguishing between the two types of Glioblastoma—the progressive and de novo types. Also disclosed is a method of prognosis of glioblastoma based on the expression of the gene PBEF1, wherein the higher level of expression of the gene in the tumor sample, indicates poorer survival of the human subject. The disclosed compositions are useful, for example, in the diagnosis, prevention, treatment and/or prognosis of astrocytoma. The invention further provides kits for the detection and prognosis of the said diseases.
US08883417B2	Clinically intelligent diagnostic methods utilizing micromixers disposed in wells The invention relates to the clinically intelligent design of diagnostic devices (such as microarrays) and methods of making and using such devices in differential diagnoses of specific clinical symptoms or sets of symptoms. In one aspect, the devices include various probes used to perform parallel screening of a number of analytes. The probes are clustered on the devices based on known clinical presentations of symptoms associated with specific diseases and disorders.
US08883415B2	Aza-benzazolium containing cyanine dyes Unsymmetrical cyanine dyes that incorporate an aza-benzazolium ring moiety are described, including cyanine dyes substituted by a cationic side chain, monomeric and dimeric cyanine dyes, chemically reactive cyanine dyes, and conjugates of cyanine dyes. The subject dyes are virtually non-fluorescent when diluted in aqueous solution, but exhibit bright fluorescence when associated with nucleic acid polymers such as DNA or RNA, or when associated with detergent-complexed proteins. A variety of applications are described for detection and quantitation of nucleic acids and detergent-complexed proteins in a variety of samples, including solutions, electrophoretic gels, cells, and microorganisms.
US08883411B2	Making nucleic acid sequences in parallel and use The present invention relates generally to the fields of genomics, synthetic biology and genetic engineering. More particularly, the present invention concerns the methods that enable parallel multiplex ligation and amplification on surface for making assemblies of nucleic acids of various biological applications and for analysis of biological samples such as DNA, RNA, and proteins.
US08883407B2	Coating compositions suitable for use with an overcoated photoresist In one aspect, organic coating compositions, particularly antireflective coating compositions, are provided that comprise a diene/dienophile reaction product. In another aspect, organic coating compositions, particularly antireflective coating compositions, are provided that comprise a component comprising a hydroxyl-naphthoic group, such as a 6-hydroxy-2-naphthoic group Preferred compositions of the invention are useful to reduce reflection of exposing radiation from a substrate back into an overcoated photoresist layer and/or function as a planarizing, conformal or via-fill layer.
US08883405B2	Method for forming pattern According to one embodiment, a method is disclosed for forming a pattern. The method can include forming a resist film above a subject. The resist film includes a photosensitive material. The resist film has a concentration profile having a concentration of the photosensitive material being higher on a side of a bottom of the resist film than on a side of a surface of the resist film. A portion of the resist film has a maximum concentration of the photosensitive material existing closer to the side of the bottom than a center of the resist film in a thickness direction. The method can include irradiating the resist film with a light from the side of the surface. The method can include developing the resist film after the resist film being irradiated with the light.
US08883403B2	Method of semiconductor integrated circuit fabrication A method of fabricating a semiconductor integrated circuit (IC) is disclosed. The method includes providing a substrate having two different topography areas adjacent to each other. A step-forming material (SFM) is deposited over the substrate. A patterned SFM is formed in the low topography area of the two areas. The formation of the patterned SFM provides a fairly planar surface across over the substrate.
US08883402B2	Photocurable compositions A photocurable composition comprising a photoresist component, and an ethylenically unsaturated perfluoropolyether is disclosed. The composition enables easier release of phototool from a photoresist.
US08883398B2	Photoactive compound and light-sensitive resin composition comprising same The present application relates to a photoactive compound including an oxime ester group and a phosphonate group together, and a photosensitive resin composition comprising the same, the compound of the present application having excellent storage stability and high-temperature process characteristics.
US08883397B2	Positive photosensitive siloxane composition A positive photosensitive siloxane composition containing: a polysiloxane (Ia), which is obtained by hydrolyzing and condensing the silane compound represented by RSi(OR1)3 in general formula (1) and the silane compound represented by Si(OR1)4 in general formula (2) in the presence of a basic catalyst, and a pre-baked film of which has a dissolution rate of 1,000 Å/second or less in a 5 wt % TMAH aqueous solution; a polysiloxane (Ib), which is obtained by hydrolyzing and condensing at least the silane compound represented by general formula (1) in the presence of an acid or basic catalyst, and a pre-baked film of which has a dissolution rate of 100 Å/second or more in a 2.38 wt % TMAH aqueous solution; and a diazonaphthoquinone derivative and solvent. (In the formula: R represents a linear, branched or cyclic alkyl group having 1 to 20 carbon atoms, in which any methylene may be replaced by oxygen, or represents an aryl group having 6 to 20 carbon atoms, in which any hydrogen may be replaced by fluorine; and R1 is an alkyl group having 1 to 5 carbon atoms.)
US08883395B2	Fluorine-free fused ring heteroaromatic photoacid generators and resist compositions containing the same The present invention relates to a fluorine-free photoacid generator (PAG) and a photoresist composition containing the same. The PAG is characterized by the presence of an onium cationic component and a fluorine-free fused ring heteroaromatic sulfonate anionic component containing one or more electron withdrawing substituents. The onium cationic component of the PAG is preferably a sulfonium or an iodonium cation. The photoresist composition further contains an acid sensitive imaging polymer. The photoresist composition is especially useful for forming material patterns on a semiconductor substrate using 193 nm (ArF) lithography.
US08883394B2	Chemically amplified photoresist composition and method for forming resist pattern The present invention provides a resist composition giving a resist pattern excellent in CD uniformity and focus margin. A chemically amplified photoresist composition comprises a resin (A) and an acid generator (B), and the resin (A) contains, as a part or an entirety thereof, a copolymer (A1) which is obtained by polymerizing at least: a (meth)acrylic monomer (a1) having C5-20 alicyclic hydrocarbon group which becomes soluble in an aqueous alkali solution by the action of an acid; a (meth)acrylic monomer (a2) having a hydroxy group-containing adamantyl group; and a (meth)acrylic monomer (a3) having a lactone ring, and the copolymer (A1) has a weight-average molecular weight of 2500 or more and 5000 or less, and a content of the copolymer (A1) is not less than 50 parts by mass with respect to 100 parts by mass of the resin (A).
US08883391B2	Positive type photosensitive resin composition Disclosed is a positive-type photosensitive resin composition which has excellent storage stability, particularly excellent sensitivity stability, and can be formed into a cured film having excellent adhesion onto a substrate when heated at 350° C. or higher or heated in the air. The positive-type photosensitive resin composition comprises (a) a polymer having, as the main component, at least one structure selected from the group consisting of a polyimide precursor structure, a polybenzoxazole precursor structure, and a polyimide structure, (b) a quinonediazide compound, (c) a silane coupling agent having a styryl group, (d) a silane coupling agent having an epoxy group, an oxetanyl group, a methacryloxy group, an acryloxy group, an amino group, an amide group or mercapto group and an alkoxysilyl group, and (e) a solvent.
US08883389B2	Developing apparatus and developing method An object of the present invention is to provide a developing apparatus which is less affected by usage environments, has high development efficiency for long term use and can provide a high quality image without image density non-uniformity.The present invention relates to a developing apparatus wherein a magnetic toner-carrying member has a work function value at the surface thereof within a specific range, a toner regulating member which regulates toner carried on the magnetic toner-carrying member is made of a specific material at a portion contacting the magnetic toner, the magnetic toner has an average circularity of 0.950 or more and the magnetic toner has a surface tension index within a specific range.
US08883380B2	Film exposure method On a film where an exposure material coating has been formed in a exposure pattern formation region on a film base material, a colored firing material, colored light-curable material, or colored ink is applied to at least one of two widthwise side edges to form a side part application coating, which is irradiated with laser light by an alignment mark formation unit to form an alignment mark. The alignment mark is then used to detect film meandering and adjust the positions of masks. This makes it easy to form the alignment mark and detect the alignment mark thus formed and makes it possible to accurately correct for meandering of a film and stably expose the film in the process of continuous exposure of a film where an exposure material coating has been formed in a exposure pattern formation region on a film base material.
US08883378B2	Colored curable composition, color filter and method of producing color filter, solid-state image sensor and liquid crystal display device The present invention provides a colored curable composition including a phthalocyanine pigment, a dioxazine pigment, a dye, a polymerization initiator, a polymerizable compound and a solvent; and a colored curable composition including a phthalocyanine pigment, a dye multimer having a polymerizable group and a group derived from a dipyrromethene dye, a polymerization initiator, a polymerizable compound and a solvent.
US08883377B2	Photoresist composition for forming a color filter and method of manufacturing a substrate for a display device A photoresist composition for forming a color filter, the composition including a binder resin, a monomer, a photo initiator, a dye compound including epoxy group, and an organic solvent.
US08883375B2	Method and system for forming a pattern using charged particle beam lithography with multiple exposure passes In the field of semiconductor production using charged particle beam lithography, a method and system for fracturing or mask data preparation or proximity effect correction is disclosed, wherein a plurality of exposure passes are used, and where the sum of the base dosage levels for all of the exposure passes does not equal a normal dosage. Methods for manufacturing a reticle and manufacturing an integrated circuit are also disclosed, wherein a plurality of charged particle beam exposure passes are used, and where the sum of the base dosage levels for all of the exposure passes is different than a normal dosage.
US08883373B2	Method for manufacturing photo mask, method for manufacturing semiconductor device, and program According to one embodiment, a method for manufacturing a photo mask, includes acquiring first data on respective shapes of a plurality of mask substrates, acquiring second data on respective shapes of a plurality of pellicles, and determining a combination of the mask substrate and the pellicle based on the first data and the second data.
US08883372B2	Reticle with composite polarizer and method of simultaneous optimization of imaging of a set of different patterns A reticle with a composite polarizer includes: a transparent substrate; a patterned layer disposed on said transparent substrate; and a polarizing filter disposed on said transparent substrate, wherein said transparent substrate is substantially transparent with respect to illumination light, said patterned layer is partially opaque with respect to said illumination light, and said polarizing filter is capable of selectively polarizing said illumination light.
US08883363B2	Fuel gas supply device of fuel cell system A fuel gas supply device for supplying fuel gas to a fuel cell stack includes a control valve provided in a fuel gas path connecting a fuel tank and the fuel cell stack, an upstream-side pressure sensor and a downstream-side pressure sensor for detecting an upstream-side pressure and a downstream-side pressure, and a programmable controller. The programmable controller calculates a required opening based on a target fuel gas pressure and the downstream-side pressure and calculates an opening time and a closing time based on the required opening and the upstream-side pressure, or calculates an opening time and a closing time based on the target fuel gas pressure and the downstream-side pressure and calculates a required opening based on the opening time and the upstream-side pressure, and controls the control valve using the calculated required opening, opening time and closing time.
US08883362B2	Fuel cell system A case configuring a fuel cell system is divided into a module section, a first fluid supply section, a second fluid supply section, and an electric section. The electric section is provided with a first intake vent for intake of an oxidant gas from outside the case into the electric section. The second fluid supply section is provided with a second intake vent for intake of the oxidant gas subjected to intake from the first intake vent, into an oxidant gas supply device. The case is internally provided with first and second internal partitions which generate a bypass path for blocking straight flow of the oxidant gas from the first intake vent to the second intake vent.
US08883359B2	Fuel cell system and driving method of the same A method of driving a fuel cell system is disclosed. The method of driving the fuel cell system may include supplying water to a reformer by pressing a pump pipe to pressing members to move the pressing members in a first direction, stopping power generation including stopping a supply of fuel and oxidant to the reformer, and discharging water in the reformer by moving the pressing members in a second direction opposite to the first direction while pressing the pump pipe with the pressing members. A fuel cell system is also disclosed. The fuel cell system includes a reformer, a fuel cell stack and a water transferring pump. The water transferring pump includes pressing members and a pump pipe. The pump pipe is in fluid communication with a water transferring pipe.
US08883356B2	Electrolyte for lithium batteries Electrolyte and lithium secondary batteries containing the same are disclosed. In one instance, the electrolyte includes a lithium salt, a solvent and an additive. In some examples, the additive includes substances A, B and C, wherein substance A is vinylene carbonate, substance B includes at least one of fluorinated or chlorinated ethylene carbonate or diethylene carbonate, and substance C includes at least one of ethylene sulfite, 1,3-propanesultone and propenyl sulfite.
US08883355B2	Battery including lithium ion conductive solid electrolyte and method for producing the same A lithium ion conductive glass ceramics which solves a problem of low thermal stability of the related-art lithium ion conductive glass ceramics and which is high in lithium ion conductivity, high in thermal stability of a raw glass and easy for molding is provided. The amount of a specified component in a glass ceramics (raw glass) is limited to a specified range, and specifically, a ZrO2 component is incorporated in the range of from 0.5% to 2.5% in terms of % by mass on the oxide basis.
US08883353B2	Rolled electrode for a storage battery The invention relates to a rolled electrode for a storage battery, wherein the electrode (10) is of substantially plate-like design and has a frame (12, 13, 15, 17) with a grid (16) arranged therein. A contact lug (14) for connecting the electrode to a battery pole is also provided on the frame (12, 13, 15, 17). Electrodes of this type are used, for example, in lead-acid storage batteries for vehicles, for example as a starter battery. The intention is to specify an electrode with improved electrical and mechanical properties and also possible ways of producing said electrode. To this end, the frame (12, 13, 15, 17) and/or the contact lug (14) in the electrode according to the invention have/has a greater thickness than the grid (16) arranged therein, at least in specific regions. A machine for producing such an electrode and a production method are also specified.
US08883347B2	All solid state secondary battery This is to provide an all solid state secondary battery which can be produced by an industrially employable method capable of mass-production and has excellent secondary battery characteristics.This is an all solid state secondary battery containing a laminated material in which a positive-electrode unit and a negative-electrode unit are laminated alternately through an ion conductive inorganic-material layer, the positive-electrode unit has positive active material layers on both surfaces of a positive-electrode collector layer, the above-mentioned negative-electrode unit has negative active material layers on both surfaces of a negative-electrode collector layer, (A) at least one of the positive-electrode collector layer and the negative-electrode collector layer comprises a metal of either of Ag, Pd, Au and Pt, or an alloy containing either of Ag, Pd, Au and Pt, or a mixture containing two or more kinds selected from the metals and alloys, (B) each layer is in a sintered state, or (C) at least the starting material for the ion conductive inorganic material of the ion conductive inorganic-material layer is a calcined powder.
US08883346B2	Method of manufacturing prismatic battery Provided is a method of manufacturing a prismatic battery, or a series of prismatic batteries. The method comprises stacking positive electrode plates, negative electrode plates and separator layers therebetween. The positive and negative electrode plates extend beyond a periphery of the electrode stack. The positive electrode plates are fused to form a positive current collector, and the negative electrode plates are fused to form a negative current collector.
US08883342B2	Battery assembly with temperature control device A battery module of the present invention is adaptable to be utilized in various configurations including and not limited to an overlapping battery cell packaging configuration and a vertical stack battery cell packaging configuration used in an automotive and non-automotive applications. The battery module has a plurality of battery heatsink assemblies with the cells disposed therebetween. A plurality of rods extend through the each heatsink assemblies to secure the heatsink assemblies and the cell with one another to form the battery module.
US08883341B2	Battery, vehicle mounted with the battery, and device mounted with the battery A battery is provided with a base portion provided on the base end side of a columnar rivet portion. A terminal rivet is formed, on that surface of the base portion on which the rivet portion is located, with a sloped seat surface having a height which increases as one moves closer to the rivet section and provided at the entire circumference around the rivet section. The battery is also provided with an annular elastic member and a hard member having higher hardness than the elastic member and provided with a first hole having a diameter greater than the outer diameter of the elastic member and smaller than the outer diameter of the sloped seat surface. The terminal rivet is mounted such that the base portion and a current collecting part are located inside a battery case and such that the rivet portion penetrates through a hole in the battery case to project outward. The hard member is mounted such that the elastic member is located in the first hole and is sandwiched between the base portion and the battery case. When the rivet section is riveted, the elastic member is compressed in the thickness direction between the base portion and the battery case, and as a result, reliable sealing ability is maintained for a long period.
US08883336B2	Battery pack A battery pack includes at least one battery module having a plurality of battery cells; and a housing accommodating the at least one battery module and having an inlet port at a first side thereof and discharging port at a second side thereof opposite to the first side, the housing having a bottom surface that has a slope and a first hole at an end of the slope.
US08883330B2	Glass for chemical strengthening, substrate for information recording media and information recording media A glass for use in chemical reinforcement for use in a substrate of an information recording medium, having a composition comprising, denoted as mol %: SiO247 to 70% Al2O31 to 10% (where the total of SiO2 and Al2O3 is 57 to 80%) CaO2 to 25% BaO1 to 15% Na2O1 to 10% K2O0 to 15% (where the total of Na2O and K2O is 3 to 16%) ZrO21 to 12% MgO0 to 10% SrO0 to 15% (where the ratio of the content of CaO to the total of MgO, CaO, SrO, and BaO is greater than or equal to 0.5) ZnO0 to 10% (where the total of MgO, CaO, SrO, BaO, and ZnO is 3 to 30%) TiO20 to 10% and the total content of the above-stated components is greater than or equal to 95%. A glass for use in chemical reinforcement for use in the substrate of an information recording medium employed in a perpendicular magnetic recording system, in which the glass exhibits the glass transition temperature is greater than or equal to 600° C. A substrate for use in an information recording medium consisting of the above glass and being chemically reinforced. A substrate for an information recording medium consisting of a chemically reinforced glass having a glass transition temperature of greater than or equal to 600° C. and exhibiting a bending strength following heating for two hours at 570° C. of greater than or equal to 15 kgf/mm2. An information recording medium comprising an information recording layer on the above substrate for an information recording medium. The present invention provides glass having both high thermal resistance and high strength, a substrate for use in information recording media comprised of this glass, and an information recording medium employing such a substrate.
US08883327B2	Microwave assisted magnetic recording medium and information recording apparatus using the same Provided is a magnetic recording medium achieving both of reduction in switching field distribution and reduction in switching field intensity by high-frequency magnetic field, thus enabling high-density recording. Magnetic grains of the magnetic recording medium are made up of a recording layer and a resonance layer. The resonance layer is disposed closer to a protective layer 5 than the recording layer, and a magnetic material of the recording layer has anisotropy field 1.2 times or more anisotropy field of a magnetic material of the resonance layer. The magnetic material of the recording layer has saturation magnetization substantially equal to saturation magnetization of the magnetic material of the resonance layer. At the entire resonance layer and a part of the recording layer, the magnetic grains are separated from surrounding magnetic grains by a nonmagnetic material, and at a part of the recording layer, the magnetic grains are coupled with surrounding magnetic grains.
US08883326B2	Monoclinic india stabilized gadolinia A composition comprising india stabilized gadolinia wherein the india stabilized gadolinia is an oxide with a direct substitution of the indium ion for the gadolinia ion resulting in a compound with the formula InxGd2-xO3.
US08883325B2	Electroluminescent device using azomethine-lithium-complex as electron injection layer In OLEDs, improved efficiency is obtained by compounds which can form inter alia electron injection layers of the formula (I) wherein R1 is a 1-5 ring aryl (including polycyclic), aralkyl or heteroaryl group which is optionally substituted with one or more C1-C4 alkyl, alkoxy or cyano; R2 and R3 together form a 1-5 ring aryl (including polycyclic), aralkyl or heteroaryl group which is optionally substituted with C1-C4 alkyl, alkoxy or cyano; R4 is hydrogen, C1-C4 alkyl or aryl; and Ar is monocyclic, bicyclic or tricyclic aryl or heteroaryl which is optionally substituted with one or more C1-C4-alkyl or alkoxy groups, or an oligomer thereof.
US08883323B2	Organic electroluminescence device An organic electroluminescence device that includes an anode, an emitting layer that includes a host and a dopant, a blocking layer, an electron injecting layer, and a cathode where the blocking layer includes an aromatic heterocyclic derivative, the triplet energy ETb (eV) of the blocking layer is larger than a triplet energy ETh (eV) of the host, and the affinity Ab (eV) of the blocking layer and an affinity Ae (eV) of the electron injecting layer satisfy a relationship of Ae−Ab<0.2.
US08883322B2	Pyridyl carbene phosphorescent emitters Organometallic compounds comprising an imidazole carbene ligand having a N-containing ring fused to the imidazole ring are provided. In particular, the N-containing ring fused to the imidazole ring may contain one nitrogen atom or more than one nitrogen atom. These compounds may demonstrate high photoluminescent (PL) efficiency, Gaussian emission spectra, and/or short excited state lifetimes. These materials may be especially useful as blue phosphorescent emitters.
US08883321B2	Polymerizable compositions and organic light-emitting devices containing them Compositions of a mixture of a thiol material and a material that contains a reactive unsaturated carbon-carbon bond that can be polymerized to form a charge-transporting or luminescent film are described, as is an organic light-emitting diode (OLED) device comprising at least one such charge-transporting or emissive layer that has been formed by polymerizing a thiol material and an ene material. The process for forming such an OLED, including the deposition of a layer of material comprising the polymerizable composition, from solution, exposing said layer to actinic radiation through a mask, and then optionally developing said film to form a photopatterned film, is also disclosed.
US08883320B2	Light-emitting device A light emitting device comprising: an anode; a cathode; a light emissive layer located between the anode and the cathode, said light emissive layer comprising a charged metal complex for emitting light and a counterion or counterions with sufficient charge to balance the change on the charged metal complex; characterized in that the counterion or counterions are substantially immobile so (that light output from the device is immediate, provided that the combined charged metal complex and counterion do not have General Formula: (I) or (II); where C—N is a cyclometallated liquid.
US08883315B2	Adhesive composition for glass bonding, glass assembly and display using the same Disclosed are an adhesive composition for glass bonding, a glass assembly and a display using the adhesive composition. The adhesive composition includes a urethane-acryl copolymer, a monomer mixture of an acrylic monomer having no hydroxyl group and a monomer having a hydroxyl group, an isocyanate cross-linking agent, and a photo-polymerization initiator. The adhesive composition has advantages of: favorable scattering prevention of broken glass pieces, excellent heat-resistant durability enabling prevention of damage to an image display apparatus caused by temperature change, no adverse effect upon transmittance of the image display apparatus, hence ensuring desired visibility.
US08883309B2	Silicate-based blue light-emitting phosphor and method for producing same A blue light-emitting silicate phosphor favorably employable as a blue light-emitting source of a light-emitting apparatus which gives emission of a visible light upon irradiation of ultraviolet rays having a wavelength of 254 nm, such as ultraviolet rays emitted by a fluorescent lamp is produced by a method comprising calcining a powdery mixture comprising a magnesium oxide powder, an MeO source powder, a EuO source powder and a SiO2 source powder, said magnesium oxide powder having a purity of 99.9 wt. % or higher and a BET specific surface area in the range of 3 to 60 m2/g and having been prepared by bringing a metallic magnesium vapor into contact with oxygen whereby oxidizing the metallic magnesium vapor.
US08883308B2	High surface area fibrous silica nanoparticles Disclosed are high surface area nanoparticles that have a fibrous morphology. The nanoparticles have a plurality of fibers, wherein each fiber is in contact with one other fiber and each fiber has a length of between about 1 nm and about 5000 nm. Also disclosed are applications of the nanoparticles of the present invention, and methods of fabrication of the nanoparticles of the present invention.
US08883307B2	Spherical particle of crystalline mannitol [Summary][Problems] To provide extremely-spherical-three-dimensional-shaped particles of crystalline mannitol containing large hollows and gaps inside.[Solution] Spherical particles of crystalline mannitol made by spray drying, extremely spherical (having an aspect ratio of 1.0 to 1.2), high oil absorption rates according to test method A, wherein powder has a mean particle diameter of 15 to 165 μm, a loose bulk density of 0.35 to 0.60 and an angle of repose of 30 to 50 degrees, and has a hardness of 7 to 20 kgf, when directly compressed.
US08883298B2	Polyester film for solar cells The invention provides a polyester film suitable for a back sheet for solar cells, which requires a high reflectance not only in the visible light region but also in the near-infrared region, and also requires a low reflection directivity. The polyester film is a cavity-containing polyester film having an average reflectance of 70-95% in a wavelength range of 400-1200 nm and an average transmittance of 5-30% in a wavelength range of 700-1200 nm.
US08883297B2	Methods for bonding porous flexible membranes using solvent A method for bonding a porous flexible membrane to a rigid material is disclosed. In some embodiments, the method includes applying, at a bonding site of the porous membrane, a pre-treatment solvent solution, drying the bonding site of the porous membrane, applying, at a bonding site of the rigid structure, a first solvent that is capable of dissolving a surface of the rigid material, applying, at the bonding site of the porous membrane, a second solvent that is capable of dissolving the polymeric residue material dissolved in the pre-treatment solvent solution, and pressing the porous membrane to the rigid material at their respective bonding sites. In some embodiments, the pre-treatment solvent solution may include a solvent carrying dissolved polymeric residue material configured to fill the pores of the porous membrane at the bonding site of the porous membrane.
US08883295B2	Biodegradable film for advertisement The present invention relates to a biodegradable film for advertisement. In the present invention, films, to which the biodegradable polymer is applied as a cover layer having excellent printability with respect to various solvent inks or bio inks, are used as materials for indoor or outdoor advertisement, such as banners and flexes. Therefore, the present invention can provide environment-friendly biodegradable materials for advertisement, which do not discharge harmful substances during incineration, and can be easily decomposed on landfill treatments.
US08883293B2	Digital printed applique emblem A process for applying digitally printed applique” indicia which results in decorative and identification elements for decoration and identification when applied to uniforms, fashion, “basic” and performance apparel, swimwear and intimate apparel as well as other textile products, the elements being an alternative to direct embroidery, embroidered emblems, thermo-transfer films, silk screen or sublimated printing. The production process includes the following phases (FIGS. 3A-C): a design phase (1); a separation phase (2); a printing phase (3); an optional traditional embroidery phase (4); and an etching/cutting phase (5). The process can incorporate embroidered elements but has the benefit of reducing or eliminating portions of stitching and or extra applique layers in the emblem. The resulting product has superior care and durability characteristics to screen printing and heat transfers as the image is more wash fast and can be ironed. The heat or pressure transfer capability can allow much faster customization of finished garments.
US08883283B2	Composite laminate product A laminated product (1) that forms a deformable cellular structure, comprising: an upper band (2) and a lower band (3) both oriented in the same main direction (X); and between the two bands and connecting the latter in zones (4a, 4b) referred to anchoring zones, a series (5A, 5B, 5C) that extends in the direction X, of cylindrical structures (5) referred to connecting cylindrical structures that are non-touching in the direction X. Each connecting cylindrical structure (5) comprises a plurality of preferably concentric elementary cylinders (5a, 5b) having their generatrix oriented along an axis Y perpendicular to the direction X, said elementary cylinders being fitted one inside the other and interconnected to one another in each anchoring zone (4). Said elementary cylinders are especially composite cylinders comprising fibers embedded in a resin matrix. Such a laminated product can be used as an elastic beam having a high resistance to flexural/compressive stresses and having a high endurance to such repeated or alternated stresses, in particular as a shear band in a non-pneumatic resilient wheel.
US08883275B2	Inkjet recording medium and ink set, and inkjet recording method A inkjet recording medium and ink set including ink containing water, a hydrosoluble organic solvent comprising an amide compound represented by the following Chemical Structure 1, a surface active agent; and a coloring agent, and a recording medium containing a substrate; and a coated layer on at least one side of the substrate, wherein the transfer amount of pure water to the recording medium having the coated layer is 2 ml/m2 to 35 ml/m2 during a contact time of 100 ms and 3 ml/m2 to 40 ml/m2 during a contact time of 400 ms when measured by a liquid dynamic absorption tester at 23° C. and 50% RH:
US08883273B2	Photonic crystal security device An optically variable security device comprises a photonic crystal of which incident light received by the crystal is selectively reflected or transmitted by the crystal to generate a first optically variable effect observable over a first set of directions. Incident light received by the crystal is also selectively reflected or transmitted by the crystal to generate an optical effect observable over a second set of directions that is different from the first set.
US08883271B2	Polymerizable chiral compound, polymerizable liquid crystal compound, liquid crystal polymer and optically anisotropic body The present invention is to provide a novel polymerizable chiral compound (chiral agent) having high left-handed helical twisting power, a polymerizable liquid crystal composition comprising the polymerizable chiral compound and a polymerizable liquid crystal compound, a liquid crystal polymer, and an optically anisotropic body.The object was achieved by a left-handed-helix-inducing polymerizable chiral compound represented by the following formula (I), a polymerizable liquid crystal composition comprising the polymerizable chiral compound and a polymerizable liquid crystal compound, a liquid crystal polymer and an optically anisotropic body: wherein X represents the following formula (X-i) or (X-ii) wherein * represents a bond: wherein Y1 to Y6 are each one selected from the group consisting of —O—, —S—, —O—C(═O)—, —C(═O)—O— and so on; Yx is one selected from the group consisting of —C(═O)—, —O—C(═O)—, —CH═CH—C(═O)—, —CH2— and so on; Yz is one selected from the group consisting of —C(═O)—, —C(═O)—O—, —C(═O)—CH═CH— and so on; G1 and G2 are each a divalent aliphatic group which has 1 to 20 carbon atoms and which may have a substituent; Z1 and Z2 are each an alkenyl group which has 2 to 10 carbon atoms and which may be substituted by a halogen atom; Q1 to Q4 are each a hydrogen atom or an alkyl group which has 1 to 6 carbon atoms and which may have a substituent; A1 to A6 are each a divalent organic group having 1 to 30 carbon atoms; and a and b are each 0 or 1.
US08883270B2	Systems and methods for thin-film deposition of metal oxides using excited nitrogen—oxygen species Systems and methods are delineated which, among other things, are for depositing a film on a substrate that is within a reaction chamber. In an exemplary method, the method may comprise applying an atomic layer deposition cycle to the substrate, wherein the cycle may comprise exposing the substrate to a precursor gas for a precursor pulse interval and then removing the precursor gas thereafter, and exposing the substrate to an oxidizer comprising an oxidant gas and a nitrogen-containing species gas for an oxidation pulse interval and then removing the oxidizer thereafter. Aspects of the present invention utilize molecular and excited nitrogen-oxygen radical/ionic species in possible further combination with oxidizers such as ozone. Embodiments of the present invention also include electronic components and systems that include devices fabricated with methods consistent with the present invention.
US08883269B2	Thin film deposition using microwave plasma A method of processing a substrate in a processing chamber is provided. The method generally includes applying a microwave power to an antenna coupled to a microwave source disposed within the processing chamber, wherein the microwave source is disposed relatively above a gas feeding source configured to provide a gas distribution coverage covering substantially an entire surface of the substrate, and exposing the substrate to a microwave plasma generated from a processing gas provided by the gas feeding source to deposit a silicon-containing layer on the substrate at a temperature lower than about 200 degrees Celsius, the microwave plasma using a microwave power having a power density of about 500 milliWatts/cm2 to about 5,000 milliWatts/cm2 at a frequency of about 1 GHz to about 10 GHz.
US08883259B2	Thin film deposition apparatus A thin film deposition apparatus is disclosed. In one embodiment, the apparatus includes i) a deposition source configured to discharge a deposition material, ii) a deposition source nozzle unit disposed at a side of the deposition source and comprising a plurality of deposition source nozzles arranged in a first direction and iii) a patterning slit sheet disposed opposite to the deposition source nozzle unit and comprising a plurality of patterning slits arranged in a second direction substantially perpendicular to the first direction. The patterning slit sheet may include: i) a base sheet, in which a plurality of sub-patterning slits are formed in the second direction and ii) a plurality of patterning bars disposed between adjacent sub-patterning slits to form the patterning slits. Further, the deposition apparatus is configured to perform deposition while the substrate is moved relative to the thin film deposition apparatus in the first direction.
US08883256B2	Process for the internal coating of hollow bodies using a plasma beam at atmospheric pressure A coating method for the internal coating of a hollow body which includes producing a plasma jet from a working gas, supplying at least one precursor material to the working gas and/or to the plasma jet, introducing the plasma jet through a first opening into an interior of the hollow body and depositing at least one reaction product of at least one precursor on an inner surface of the hollow body and/or on at least one layer arranged on the inner surface. The method is carried out at atmospheric pressure. Furthermore, the first internal coating takes place without an activation process directly after a production process of the hollow body, in which the hollow body is formed with the supply of heat.
US08883251B2	Antistatic optical film, method for manufacturing the same and image viewing display An antistatic optical film comprising an antistatic layer laminated on at least one side of an optical film, wherein the antistatic layer comprises a water soluble or a water dispersible conductive polymer, has excellent antistatic effect, optical characteristics and appearance.
US08883247B2	Array of small contacts for solar cell fabrication Fabrication of a solar cell using a printed contact mask. The contact mask may include dots formed by inkjet printing. The dots may be formed in openings between dielectric layers (e.g., polyimide). Intersections of overlapping dots may form gaps that define contact regions. The spacing of the gaps may be dictated by the alignment of nozzles that dispense the dots. Using the dots as a contact mask, an underlying dielectric layer may be etched to form the contact regions through the underlying dielectric layer. Metal contact fingers may be formed over the wafer to form electrical connections to corresponding diffusion regions through the contact regions.
US08883245B2	Method of coating surgical needles A novel silicone coating process for surgical needles is disclosed. Coating solutions are applied to a surgical needle and a stream of air is directed at the needle in a direction substantially parallel to the central longitudinal axis of the distal section of the needle, providing superior coatings and performance.
US08883242B1	Bowl for keeping breakfast cereal crispy Disclosed is a bowl that has a cereal section and a milk and fruit section that are separated by a continuous dividing wall. The milk and fruit section has a downward slope from the dividing wall that causes the milk to enter a curved bottom section from which the eater can take the last of the cereal and milk onto his/her spoon. Also disclosed is a cover for the bowl that makes a liquid tight seal on the milk and fruit section and also covers the cereal section.
US08883241B2	Stabilized edible oil-in-water emulsion comprising ground, pulse seed The present invention relates to edible oil-in-water emulsions that have been stabilized by incorporation of a small quantity of ground, pulse seed and a related process of production thereof. More particularly, the invention provides an edible oil-in-water emulsion comprising: 15-80 wt. % of a continuous aqueous phase, said aqueous phase having a pH in the range of 3.0-5.0; 20-85 wt. % of a dispersed oil phase comprising more than 80 vol. % of oil droplets having a diameter of less than 20 μm; wherein the emulsion has an elastic modulus G′ at 20° C. of 100-3500 Pa and contains 0.1-8% of finely ground pulse seed, calculated as dry matter by weight of aqueous phase, said finely ground pulse seed being obtained from pulse seed having the following composition, calculated on dry matter: 30-60 wt. % of starch; 1-40 wt. % of dietary fiber; 0.5-12 wt. % of sugars; 15-35 wt. % of protein; 0.8-12 wt. % of oil; wherein starch, dietary fiber, sugars, protein and oil together make up 95-100 wt. % of the dry matter contained in the pulse seed; and wherein the pulse seed contains starch and protein in a weight ratio of 2:3 to 3:1.
US08883238B2	Fresh fruit preservative and method of using same A fresh fruit preservative and method of using the preservative for fresh cut fruit that significantly extend the shelf life of fresh cut fruit are provided. The fresh fruit preservative preserves the texture, flavor, appearance, and color of the fresh fruit, particularly exposed surfaces of the fresh fruit that have been cut, in particular by reducing oxidation of the exposed cut surfaces of the fruit. The preservative includes the ingredients of ascorbic acid, calcium ascorbate, carbohydrate, citric acid, calcium carbonate, sodium chloride, magnesium chloride, potassium bicarbonate, malic acid and a protein-based composition.
US08883235B2	Ingredient delivery system for popcorn kernels An ingredient delivery system for popcorn kernels is described. The ingredient delivery system can include multiple layers. The synergy formed from the multiple layers of the ingredient delivery system results in a popped popcorn with minimal flaking and blow-off. Thus, a greater ingredient impact is imparted to the consumer. Also, the layer combination minimizes any hindrance of the natural popping action of the kernels. Thus, consumers have a greater pop volume for consumption.
US08883233B2	Animal feed composition Disclosed is an animal feed composition that comprises free indole acetic acid (free IAA) or a derivative thereof. Also disclosed is a method for enhancing animal growth by feeding the animal with a composition according to the invention. Further disclosed is the use of free IAA or a derivative thereof in a method of therapy of animals in need of a growth-promoting treatment, such as immunocompromised animals, animals with a growth deficit or slow-growing animals. Disclosed is the use of free IAA or a derivative thereof for the preparation of a therapeutical composition for increasing the growth rate and/or the feed conversion rate and/or the immunity of animals in need of such a treatment, in particular, immunocompromised or slow-growing animals. A composition may be in the form of a food or feed supplement.
US08883230B2	Use of black soybean for treating ophthalmic diseases A method for treating a disease or disorder associated with retinal pigment epithelium (RPE) disturbance, comprising administering to a human in need thereof an effective amount of a black soybean (Glycine max (L.) Merr) product is provided, wherein the black soybean product is the seed coats of black soybean or an alcoholic extract of black soybean or seed coats thereof.
US08883229B2	Pesticidal compositions and related methods The present invention relates to a botanical repellent composition intended for pest insect control. In some embodiments, the composition may contain about 75% to about 92% garlic extract (Allium sativum) and about 8% to about 25% humic acids and diluents.
US08883225B2	Water-soluble pharmaceutical compositions of hops resins The present invention is drawn to water-soluble compositions for providing hops constituents, particularly alpha acids, iso-alpha acids, and beta acids. A pharmaceutical gel composition can comprise a hops extract and a surfactant. Such compositions can be formulated into products for various therapeutic applications, including oral and topical uses. Such compositions can also be dissolved in water to yield a clear solution containing more dilute hops acids. The invention also provides methods of treatment comprising administering water-soluble hops compositions. The present invention is also drawn to methods for making water-soluble preparations of hops constituents.
US08883224B2	Topical skin care formulations comprising plant extracts Disclosed are topical skin compositions and corresponding methods for their use that include plant extracts. One such composition can include a TNF-α inhibitor, wherein said inhibitor is an aqueous extract from the whole plant of Polygonum multiflorum, an antioxidant and a tyrosinase inhibitor, wherein said antioxidant and tyrosinase inhibitior is an aqueous extract from the whole plant of Lonicera japonica, and a dermatologically acceptable carrier, wherein the composition can include at least 50% by weight of water.
US08883223B2	Calcium carbonate granulation Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet sizes upon compression than previously available.
US08883222B2	Disinfectant materials and methods A disinfectant combination comprises a first supply of a water-soluble hypochlorite; and a second supply of at least one saturated, water-soluble, physiologically acceptable carboxylic acid in solution in an alcoholic solvent which comprises ethanol and optionally water. The combination is used in a method of disinfection, in which a dosed amount of the first supply is mixed with a dosed amount of the second supply to form a disinfectant in situ, and the resulting combined solution, optionally diluted with further water, is applied to a surface or article to be disinfected. In a preferred embodiment, the combination is used for disinfection of endoscopes.
US08883218B2	Anti-cancer nanoparticle compositions and methods of use The present invention encompasses a composition capable of delivering and expressing a nucleic acid encoding UDP-Glucuronosyltransferases, p53 or a combination thereof into a cell, and methods for treating tumors.
US08883217B2	Modified release formulations containing drug-ion exchange resin complexes An aqueous liquid suspension containing a coated drug-ion exchange resin complex comprising a core composed of an amphetamine complexed with a pharmaceutically acceptable ion-exchange resin and an uncoated amphetamine-ion exchange resin complex is provided. The coated amphetamine-ion exchange resin complex is in admixture with a polymer to form a matrix. Methods of making the coated complex and the liquid suspension are described.
US08883215B2	Metal oxide particles aftertreated with organic phosphorus compounds The invention relates to metal oxide particles and/or metal hydroxide particles, aftertreated with an organic phosphorus compound, process for the preparation thereof, and compositions comprising same.
US08883212B2	Tooth film formulations The invention provides novel dental film-forming compositions, comprising i. an acrylate/octylacrylamide copolymer, ii. one or more alkyl cellulose ethers, and iii. a solvent, and optionally further comprising whitening materials and/or active agents, together with method for using the same.
US08883210B1	Tissue-derived tissuegenic implants, and methods of fabricating and using same The disclosure provides implants containing a plurality of particles containing at least one population of viable tissuegenic cells adherent to and resident in the growth-conductive matrix or at least viable population of tissuegenic cells caused to be in contact with the growth-conductive matrix; methods to fabricate implants; methods of fabricating the implants; and use of the implants in tissue repair.
US08883209B2	Pharmaceutical solid dispersions A composition comprises a solid dispersion comprising a low-solubility drug and at least one polymer. At least a major portion of the drug in the dispersion is amorphous. The polymer has a glass transition temperature of at least 100° C. measured at a relative humidity of fifty percent. Another aspect of the invention comprises the same composition except that the dispersion has a glass transition temperature of at least 50° C. at a relative humidity of fifty percent. In another aspect of the invention, a composition comprises a solid dispersion comprising a low-solubility drug and a stabilizing polymer. At least a major portion of the drug in the dispersion is amorphous. The composition also includes a concentration-enhancing polymer that increases the concentration of the drug in a use environment. The stabilizing polymer has a glass transition temperature that is greater than the glass transition temperature of the concentration-enhancing polymer at a relative humidity of 50%.
US08883203B2	Solid oral dosage form containing an enhancer The invention relates to a pharmaceutical composition and oral dosage forms comprising a bisphosphonate in combination with an enhancer to enhance intestinal delivery of the bisphosphonate to the underlying circulation. Preferably, the enhancer is a medium chain fatty acid or a medium chain fatty acid derivative having a carbon chain length of from 6 to 20 carbon atoms, and the solid oral dosage form is a controlled release dosage form such as a delayed release dosage form.
US08883200B2	Delivery of nucleic acid-like compounds Provided herein is a process for preparing a microparticulate complex of a particle-forming component (“PFC”) and a nucleic acid-like component (“NAC”) in a monophasic composition comprising water and a water-miscible organic solvent. Also provided is a microparticulate complex that comprises a particle-forming component complexed to a nucleic acid-like component, and a composition comprising water and the microparticulate complex. Further provided is a method of delivery of a nucleic acid-like component to a cell or to a patient by contacting the cell with or administering to the patient a composition comprising water and the microparticulate complex described herein. Still further, a charge-changing composition represented by the formula A-X—B is provided.
US08883197B2	Transdermal, therapeutic system with activatable oversaturation and controlled permeation promotion A transdermal therapeutic system (TTS) that is essentially composed of two compartments and is provided with activatable oversaturation and controlled permeation promotion. The invention more particularly relates to a TTS wherein an oversaturated active ingredient solution is produced in an active-substance-containing polymer matrix when the system is applied to the skin, caused by the controlled supply of one or several substances promoting the permeation of the pharmaceutical active ingredient; to the two compartments from which the inventive transdermal therapeutic system is assembled; and to the production of the transdermal therapeutic system from the two compartments.
US08883195B2	Bioactive porous bone graft implants Bioactive porous bone graft implants in various forms suitable for bone tissue regeneration and/or repair, as well as methods of use, are provided. The implants are formed of bioactive glass and have an engineered porosity. The implants may take the form of a putty, foam, fibrous cluster, fibrous matrix, granular matrix, or combinations thereof and allow for enhanced clinical results as well as ease of handling.
US08883190B2	Urologic devices incorporating collagen inhibitors Provided herein are implantable or insertable biomedical devices comprising a substrate and a collagen inhibitor on or in said substrate, and methods of treatment using the same. In some embodiments, the device is a urethral, ureteral, or nephroureteral catheter or stent. Kits comprising the same are also provided.
US08883189B2	Intraocular encapsulation of oxygenic bacteria Exemplary embodiments comprise an implantable ophthalmic device comprising at least one shell encapsulating oxygenic bacteria and growth medium and designed to increase the oxygen partial pressure in an oxygen-deprived structure of, or space within, an eye. Exemplary embodiments may be used therapeutically to treat ischemic retinopathies in situ and thereby prevent damage, for example, retinal damage.
US08883188B2	Modular bioresorbable or biomedical, biologically active supramolecular materials The present invention relates to a modular supramolecular bioresorbable or biomedical material comprising (i) a polymer comprising at least two 4H-units and (ii) a biologically active compound. Optionally, the supramolecular bioresorbable or bio medical material comprises a bioresorbable or biomedical polymer as third component to tune its properties (mechanical and bioresorption properties). The supramolecular bioresorbable or biomedical material is especially suitable for biomedical applications such as controlled release of drugs, materials for tissue-engineering, materials for the manufacture of a prosthesis or an implant, medical imaging technologies.
US08883183B2	Medical devices incorporating collagen inhibitors Provided herein are implantable or insertable biomedical devices comprising a substrate and a collagen inhibitor on or in said substrate, and methods of treatment using the same. In some embodiments, the device is an absorbable esophageal or tracheal stent. In some embodiments, the device is a vascular stent. Wound closure devices are also provided herein, including a substrate and a collagen inhibitor on or in the substrate. Also provided are surgical packings, including a substrate and a collagen inhibitor on or in the substrate. A barrier material for preventing adhesions in a subject is further provided, including a preformed or in situ formable barrier substrate and a collagen inhibitor on or in the substrate. An ointment comprising a collagen inhibitor is further provided. Kits comprising the coated substrates are also provided.
US08883180B2	Active compound combinations The invention relates to active compound combinations, in particular a fungicidal and/or insecticidal composition, comprising Isotianil (3,4-dichloro-N-(2-cyanophenyl)-5-isothiazolecarboxamide) and at least one further insecticide of the anthranilamide group and optionally one further insecticide of the neonicotinoids. Moreover, the invention relates to a method for curatively or preventively controlling the phytopathogenic fungi and/or microorganisms and/or pests of plants or crops, to the use of a combination according to the invention for the treatment of seed, to a method for protecting a seed and not at least to the treated seed.
US08883179B2	Oral care compositions and methods Described herein are compositions comprising a MMP-13 inhibitor, and methods of using the same.
US08883178B2	Dental care products with diamond particles The invention relates to a dental care product, in particular a toothpaste, comprising diamond particles. The diamond particles have sizes in a first size range from 0.3 μm to 2.5 μm, preferably from 0.5 μm to 2.0 μm, most preferably from 0.75 μm to 1.5 μm. The amount of diamond particles having sizes within the first size range is at most 2% by weight, more preferably at most 1% by weight, most preferably at most 0.5% by weight of the product. Moreover, the invention relates to a kit of parts containing a toothbrush (1) and a product as above, wherein the product is a toothpaste. The bristles (2) of the toothbrush (1) may contain abrasive particles (3), such as diamond particles. The bristles (2) may also be capable of at least temporarily retaining diamond particles.
US08883177B2	Pharmaceutical compositions for parenteral administration The invention comprises various aqueous PEG-carbohydrate-lipid based formulations of pharmaceutical active ingredients including compositions for intravenous injections. This invention relates to methods and compositions for improving solubility and the safety profile of pharmaceutical compounds. More particularly, the present invention relates to employing PEG-carbohydrate-lipid conjugates for formulating drug compositions having increased solubility or dispersivity and enhanced stability.
US08883171B2	Computationally optimized broadly reactive antigens for influenza Described herein is the development of a computationally optimized influenza HA protein that elicits broadly reactive immune response to all H5N1 influenza virus isolates. The optimized HA protein was developed through a series of HA protein alignments, and subsequent generation of consensus sequences, for clade 2 H5N1 influenza virus isolates. The final consensus HA amino acid sequence was reverse translated and optimized for expression in mammalian cells. Influenza virus-like particles containing the optimized HA protein are an effective vaccine against H5N1 influenza virus infection in animals.
US08883170B2	Adjuvant Methods and immunogenic compositions for generating an immune response against Marburg virus are provided. The immunogenic composition includes antigens obtained from a Marburg viral strain in combination with an oleanolic acid triterpene adjuvant.
US08883168B2	Modulation of immune responses by the poxviral K4 protein The present invention relates to compositions, methods, and uses involving the modulation of K4 protein activity, especially in the treatment of various diseases and in the enhancement of vaccination regimens. The invention relates to poxviruses having reduced or increased K4 protein activity, as well as methods of making and using these poxviruses. The invention further relates to K4 proteins and inhibitors of K4 protein activity, as well as methods for making and using them.
US08883166B2	Combination vaccines with whole cell pertussis antigen Vaccines have been studied that comprise (a) D-T-Pw-HepB-Hib antigens and (b) one or more meningococcal conjugate antigens. A number of improvements and variations of these vaccines have been discovered. The vaccines can be prepared extemporaneously at the time of use by mixing together two components: (a) a first component comprising D, T, wP and HBsAg antigens; and (b) a second component comprising a Hib conjugate and one or more meningococcal conjugates.
US08883163B2	Immunogenic composition The present application discloses an immunogenic composition comprising a Hib saccharide conjugate, at least one additional bacterial, for example N. meningitidis, saccharide conjugate(s), and a further antigen selected from the group consisting of whole cell pertussis and hepatitis B surface antigen, wherein the saccharide dose of the Hib saccharide conjugate is less than 5 μg.
US08883161B2	Fusion polypeptide against EB virus-induced tumor and colicin Ia mutant The present invention provides a fusion polypeptide against EB virus-induced tumor, which comprises an antibody or a mimetic antibody against EB virus and an ion channel forming colicin selected form E1, Ia, Ib, A, B, N and their mutants. The present invention also provides a colicin Ia mutant, which comprises mutations of G11A, H22G, A26G, V31L, and H40D. The present invention also provides a gene, vector, preparation method and use of the fusion polypeptide, and provides a gene and use of the mutant.
US08883150B2	Soluble “heavy-chain only” antibodies The present invention provides a high affinity, antigen-specific, soluble heavy chain-only antibody which: lacks hallmark camelid-related amino acid substitutions and has FR2 substitutions which are not found in antibodies which comprise heavy and light chain; shows increased net hydrophobicity within CDR1 and an increased number of charged amino acids present in CDR3; and comprises one or more amino acid substitutions within the framework β-pleated sheet leading to increased net hydrophobicity within FR1 and increased number of charged amino acids present in FR3. Also provided are VH domains having the same properties, gene segments for their production, methods for their production, transgenic animals and uses of the antibody of the VH domains in therapy.
US08883147B2	Immunoglobulins insertions, deletions, and substitutions An Fc variant of a parent Fc polypeptide, wherein said Fc variant exhibits altered binding to one or more FcγRs, wherein said Fc variant comprises at least one amino acid insertion in the Fc region of said parent Fc polypeptide.
US08883146B2	Protein formulations and methods of making same The invention provides an aqueous formulation comprising water and a protein, and methods of making the same. The aqueous formulation of the invention may be a high protein formulation and/or may have low levels of conductity resulting from the low levels of ionic excipients. Also included in the invention are formulations comprising water and proteins having low osmolality.
US08883145B2	Methods of treatment with DLL4 antagonists and an anti-hypertensive agent Methods for treating cancer comprising administering a DLL4 antagonist and one or more anti-hypertensive agents are described. Also described are pharmaceutical compositions comprising a DLL4 antagonist and one or more anti-hypertensive agents, and kits comprising the same.
US08883144B2	Treatment of pulmonary vascular remodeling with neprilysin The present invention relates to agonists of Neprilysin and their use in preventing and treating pulmonary vascular remodeling. Also described are diagnostic and screening applications stemming from the inventor's discovery that Neprilysin is expressed at reduced levels in disease tissues.
US08883141B2	Stabilized liquid tenside preparation comprising enzymes A hydrolytic enzyme is stabilized in a liquid surfactant preparation using a component that stabilizes the hydrolytic enzyme and includes a phenylalkyldicarboxylic acid.
US08883140B2	Stabilized liquid tenside preparation comprising enzymes A hydrolytic enzyme is stabilized in a liquid surfactant preparation using a component that stabilizes the hydrolytic enzyme and encompasses an oligoaminobiphenyl oligocarboxylic acid.
US08883139B2	Compositions and soft tissue replacement methods The invention relates to compositions comprising a hydrogel material that comprises a glycosaminoglycan polymer, adipose tissue and a compound of the structure The composition is administered to a site of a soft tissue condition including those of breast tissue. The hydrogel material can be porous or of solid particles. The glycosaminoglycan polymer can be a hyaluronan polymer.
US08883138B2	Adiponectin production accelerating composition A problem to be solved is to provide an orally ingestible composition which promotes the production of adiponectin and which is free from safety issues such as side effects and toxicity. An adiponectin production promoting composition is prepared which comprises salmon milt extract, brewer's yeast extract, avian collagen, and yeast containing mineral and having an adiponectin production promoting activity. Preferably, the salmon milt extract comprises low molecular weight components obtained by enzymatic degradation of salmon milt into oligonucleotides and oligopeptides. Preferably, the brewer's yeast extract comprises 50 to 80% of RNA. Preferably, the mineral yeast comprises, in dry yeast, 2 to 3% of zinc, 0.3 to 0.5% of copper, and 0.01 to 0.02% of selenium. Preferably, the adiponectin production promoting composition comprises 16 to 17 parts by mass of the brewer's yeast extract, 33 to 34 parts by mass of the avian collagen, and 22 to 23 parts by mass of the yeast containing mineral per 100 parts by mass of the salmon milt extract.
US08883136B2	Methods for accelerating the healing of connective tissues injuries and disorders The invention is directed to methods for accelerating the healing of connective tissue injuries and disorders. In particular, the invention is directed to accelerating the healing of injuries and disorders of tendons and ligaments. Such methods utilize novel compositions including, but not limited to, extraembryonic cytokine-secreting cells (herein referred to as ECS cells), including, but not limited to, Amnion-derived Multipotent Progenitor cells (herein referred to as AMP cells) and conditioned media derived therefrom (herein referred to as Amnion-derived Cellular Cytokine Solution or ACCS), including pooled ACCS, and Physiologic Cytokine Solution (PCS).
US08883130B2	Transparent antiperspirant gels The present invention relates to transparent antiperspirant compositions in the form of a water-in-oil emulsion, which contain a balanced mixture of selected oil components and emulsifiers in order to improve the antiperspirant effect.
US08883123B2	Use of vaccines for the treatment/prevention of the transmission of pathogens The present invention relates to a method of reducing the transmission of a pathogen from an animal of a first species to an animal of a second species. Specifically, reduction of transmission is accomplished through the administration of antigen of the pathogen such that administration results in the reduction or absence of the reproduction of the pathogen in the animal to which the antigen was administered.
US08883118B2	Hydrocarbon-decomposing porous catalyst body and process for producing the same, process for producing hydrogen-containing mixed reformed gas from hydrocarbons, and fuel cell system A process for producing the porous catalyst body for decomposing hydrocarbons, the body containing at least magnesium, aluminum and nickel, and has a pore volume of 0.01 to 0.5 cm3/g, an average pore diameter of not more than 3006 Å and an average crushing strength of not less than 3 kgf. The process includes molding hydrotalcite containing at least magnesium, aluminum and nickel, and calcining the resulting molded product at a temperature of 700 to 1500° C.
US08883117B2	Method of enhancing thermal conductivity in hydrogen storage systems A method of forming a material for reversible hydrogen storage within a storage tank includes charging a mixture of a metal amide and a metal hydride to the storage tank, and chemically reacting the mixture at a reaction condition within the storage tank to form a thermally conducting composite material situated in the storage tank and for reversibly storing hydrogen. The composite material includes a three-dimensional and interconnected framework including a conductive metal. A method for reversibly storing hydrogen includes providing a storage tank and in situ chemically forming a composite material by charging a mixture of a metal amide and a metal hydride to the storage tank and chemically reacting the mixture at a reaction condition to form a thermally conducting composite material including a metal hydride and a substantially unreactive elemental metal framework. Hydrogen is absorbed into the composite material and is desorbed from the composite material.
US08883115B2	TiO2 nanostructures, membranes and films, and methods of making same One aspect of the present invention relates to a method for synthesizing macro-sized nanostructures. The method in one embodiment comprises the steps of mixing an amount of TiO2 powders with a volume of an alkali or alkaline solution to form a mixture, and heating the mixture at a temperature higher than 160° C. for a period of time effective to allow TiO2-containing, macro-sized nanostructures to form, wherein the TiO2-containing, macro-sized nanostructures form in an environment that has no presence of a substrate that comprises Ti. These TiO2-containing, macro-sized nanostructures can be utilized to form a free standing membrane, and/or a three-dimensional (3D) structure.
US08883113B2	Direct liquid-phase collection and processing of fullerenic materials An in-situ method and system of collecting, in a liquid, non-agglomerated fullerenic material from a gaseous suspension is provided. The method and system collects non-agglomerated fullerenic material by contacting a gaseous suspension comprising fullerenic material with a suspension liquid, so as to capture the fullerenic material in the suspension liquid; and collecting the liquid suspension as a suspension liquid containing the fullerenic material. This method and system may be particularly useful for collecting fullerenes or nanotubes and maintaining them in solution in non-agglomerated states.
US08883105B1	Removal of atmospheric pollutants from gas, related apparatus, processes and uses thereof Methods related generally to the removal of atmospheric pollutants from the gas phase, are provided, as well as related apparatus, processes and uses thereof. A single-stage air scrubbing apparatus is provided that includes at least one reaction vessel, at least one introduction duct, and a turbulence component, wherein a residence time is sufficient to allow the conversion of at least one atmospheric pollution compound to at least one other compound, molecule or atom. In some embodiments, the at least one atmospheric pollution compound comprises nitrogen oxide, sulfur oxide or a combination thereof. Additionally, methods of removing atmospheric pollution compounds from a waste gas stream are disclosed that include introducing a waste gas stream and at least one additional gas stream, mist stream, liquid stream or combination thereof into a single-stage air scrubbing apparatus at a flow rate sufficient to allow for conversion of the at least one atmospheric pollution compound.
US08883092B2	Recirculating fluidic network and methods for using the same The present invention provides a variety of microfluidic devices and methods for conducting assays and syntheses. The devices include a solid substrate layer having a surface that is capable of attaching ligand and or anti-ligand, and an elastomeric layer attached to said surface. Preferred embodiments have deflectable membrane valves and pumps, for example, rotary pumps associated therewith.
US08883090B2	Sample collector and components thereof To provide a protective coat on a refrigerated sample collector for a corrosive environment a unitary frame includes a support unit with condenser and evaporator coils mounted to the support unit and an orifice connecting the condenser and evaporator coils. The evaporator coils, condenser coils and a restrictor are powder coated after being connected, whereby an effective seal is provided for the restrictor, condenser coils and evaporator coils after they are assembled to the support. The unitary frame can be easily removed or connected as a unit to the sample collector. The bottle rack for the sample collector is made by injection molding two halves of the rack each of which has a matching surface and a bottle positioning surface. The matching surfaces are fastened together by placing the matching surfaces together back to back whereby locating members are spaced apart a sufficient distance.
US08883089B2	Sample preparation device and method utilizing polyamide tube Polyamide sample preparation tubes with a hollow polyamide tube and an extraction medium contained within the tube are utilized in the sample preparation devices. The sample preparation tubes are substantially inert and show little tendency to dissolve or leach contaminants into nonaqueous liquids. The polyamide tubes may be used in preparing samples for analytical procedures such as GC, GC/MS, LC or LC/MS.
US08883088B2	Sample preparation devices and systems Devices and system for preparing samples are described. Such devices can comprise fluidic chambers, reservoirs, and movable structures for controlling the movement of samples. The device can also comprise functional elements for performing specific operations.
US08883086B2	Apparatus and method for measuring biomedical data and measurement strip Disclosed herein are an apparatus and method for measuring biomedical data and a measurement strip. The apparatus includes a plurality of detection units arranged within a strip reception area on a plane and spaced apart from each other, a measurement type determination unit for determining whether reactive portions are present in areas of the measurement strip corresponding to the plurality of detection units based on detection results obtained by the detection units and determining a type of measurement based on results of the determination, a biomedical data measurement unit for activating part or all of the detection units according to the type of measurement determined by the measurement type determination unit, and measuring the biomedical data using the activated detection units, and an output unit for outputting the measured biomedical data to an outside.
US08883085B2	Isolator An isolator includes: a chamber to be decontaminated including an inlet provided with an intake filter and an outlet provided with a discharge filter; a first flow path through which outside air is taken into the chamber via the intake filter; a second flow path through which gas in the chamber is discharged via the discharge filter; a blower configured to take in the outside air to the chamber through the first flow path, as well as produce an air current to discharge the gas in the chamber through the second flow path; a decontaminating gas supply unit configured to supply decontaminating gas into the chamber without flowing through the intake filter and the discharge filter; and a third flow path through which the gas in the chamber is discharged via the intake filter when the decontaminating gas is supplied into the chamber.
US08883082B1	Gas distributors for circulating fluidized bed reactors A distributor for a circulating dry scrubber reactor includes a venturi section with a venturi section wall extending from a venturi section inlet to a venturi section outlet along a longitudinal axis, with the venturi section inlet connected to an inlet plenum and the venturi section outlet connected to a circulating dry scrubber reactor. A hub is mounted within the venturi section wall with an annular converging-diverging flow path defined between the venturi section wall and the hub for distribution of gas flow from the venturi section outlet into a circulating dry scrubber reactor space and for maintaining stable bed fluidization in a CDS system at a comparatively low system pressure loss.
US08883077B2	Disinfecting, nonbleaching N-halamine for use with contact lens A disinfecting, nonbleaching N-halamine for use in contact lens soaking solutions. The N-halamine compound is soluble in water and contact lens formulation solutions to the extent necessary to provide disinfection, but not to cause significant bleaching of dye materials incorporated into the contact lenses.
US08883071B2	Molten metal containment structure having movable cover An exemplary embodiment of the invention provides a molten metal containment structure, including a vessel having an internal volume for containing molten metal and an open upper end. The structure further includes a cover for the vessel having an underside facing the internal volume, the cover being movable between a closed position, covering the open upper end of the vessel with the underside of the cover, and an open position in which the cover is remote from the open upper end of the vessel to allow access to the internal volume from one side of the structure. The cover is attached to at least one lifting arm (preferably two or more) and at least on rotation control arm (preferably two or more). The lifting arm(s) operates to guide the cover from the open position to the closed position, and vice versa. The rotation control arm(s) operates to control pivoting of the cover during movement from the closed position to the open position, and vice versa, to prevent exposure of the underside of the cover, which in operation is very hot, to a person positioned adjacent to the structure at the aforesaid one side thereof. The lifting arm(s) and/or rotation control arm(s) provide a force that at least partially counterbalances a weight of the cover.
US08883069B2	Dense boron carbide ceramic and process for producing the same An aspect of the present invention is to provide an economical production technology for obtaining a dense boron carbide ceramic product without impairment to excellent mechanical properties, which boron carbide ceramics are inherently equipped with, by conducting heating under normal pressure without application of pressure and without needing addition of a large amount of a sintering additive to a raw material or needing any special additive or treatment. The present invention provides a production process in which, upon heating a boron carbide green body under normal pressure without application of pressure after pressing a boron carbide powder material to obtain the boron carbide green body, the boron carbide green body is heated with one of a powder, green body or sintered body, which contains at least one of aluminum and silicon, being disposed in a furnace.
US08883068B2	Method for improving the flatness of graphite film, graphite film, and method for producing same When a raw material graphite film bad in flatness is laminated onto another material, creases and other defects may be caused. In particular, when a graphite film having a large area is laminated, defects such as creases may be often caused. In order to solve such defects, a flatness correction treatment step is performed wherein a raw material graphite film is subjected to heat treatment up to 2000° C. or higher while a pressure is applied thereto. This flatness correction treatment gives a graphite film good in flatness. Furthermore, when the flatness of the raw material graphite film is corrected by use of a thermal expansion of a core, a graphite film small in sagging can be obtained.
US08883065B2	Curable composition for imprints, patterning method and pattern Provided is a curable composition for imprints having good patternability and dry etching resistance. Disclosed is a curable composition for imprints comprising a polymerizable monomer (Ax) having a substituent having an aromatic group and having a molecular weight of 100 or more, and a photopolymerization initiator.
US08883064B2	Method of making printed fastener A spiral fastener is provided. In another aspect, a spiral fastener, is made of layers of material and/or a light curable material. Another aspect uses a three-dimensional printing machine to emit material from an ink jet printing head to build up a fastener having a spiral formation.
US08883063B2	Mould mat for producing bone cement pellets A means to prepare bone cement pellets comprising bone cement paste which hardens through hydration a flexible mold mat having pellet cavities on both sides and a scraper for pasting the bone cement paste in to the pellet cavities where the paste is allowed to harden.
US08883059B2	Method of manufacturing a fastener clip with seal A single-piece fastener includes a relatively hard clip and a relatively soft seal. The seal can be overmolded onto the clip. A thermal bond is formed between the seal and the clip to inhibit removal of the seal from the clip. The flexible nature of the umbrella of the clip and the seal can accommodate sealing openings in panels of varying thicknesses.
US08883052B2	Polyvinyl butyral resin pellet, and method for producing the same According to the present invention, a polyvinyl butyral resin pellet is provided that gives off little odor when produced and handled, as well as has a high apparent density and favorable handleability. The present invention includes a method for producing a polyvinyl butyral resin pellet including the steps of: melting polyvinyl butyral resin powder with a water content of 0.01 to 6 wt % by means of a melt extruder that has at least one vent portion for devolatilization equipped with vacuum means, and cutting the melt of the polyvinyl butyral resin after extrusion of it from the melt extruder. The present invention further includes a polyvinyl butyral resin pellet having a total content of butyl aldehyde and 2-ethyl-2-hexenal of 100 ppm or less.
US08883049B2	Small scale microencapsulated pigments and uses thereof A method is provided for making thermochromic pigments in microcapsules having unusually small particle sizes.
US08883046B2	Conductive metal ink composition and method for forming a conductive pattern The present invention relates to a conductive metal ink composition which is properly applied for roll-printing process to form conductive pattern, and the method of preparing a conductive pattern using the same.The conductive metal ink composition comprises a conductive metal powder; a non-aqueous solvent comprising a first non-aqueous solvent having a vapor pressure of 3 torr or lower at 25° C. and a second non-aqueous solvent having a vapor pressure of higher than 3 torr at 25° C.; and a coatability improving polymer and is coated for forming the conductive pattern by the roll printing method.
US08883039B2	Fluorophor and method for production thereof and illuminator A fluorophor which comprises as a main component, an α type sialon crystal containing at least Li, A element (wherein A represents one or more elements selected from among Mn, Ce, Pr, Nd, Sm, Eu, Tb, Dy, Er, Tm and Yb), M element (wherein M represents one or more metal elements except Li and the A element), Si, Al, oxygen and nitrogen. The fluorophor has an a type sialon crystal structure which is represented by the general formulae: (Lix1, Ax2, Mx3)(Si12−(m+n)Alm+n)(OnN16−n) 1.2≦x1≦2.4 (1) 0.001≦x2≦0.4 (2) and 0≦x3≦1.0 (3), and has a luminescence peak at a wavelength in the range of 400 to 700 nm. The above phosphor is reduced in the lowering of brightness, and can be suitably used for a white LED and the like.
US08883034B2	Composition and method for polishing bulk silicon The invention provides a polishing composition comprising (a) silica, (b) one or more compounds that increases the removal rate of silicon, (c) one or more tetraalkylammonium salts, and (d) water, wherein the polishing composition has a pH of about 7 to about 11. The invention further provides a method of polishing a substrate with the polishing composition.
US08883030B2	Substrate processing apparatus and substrate processing method A substrate processing apparatus comprising a substrate holding rotating mechanism, a process liquid supply mechanism having a nozzle for dispensing a process liquid toward a principal face of the substrate, a processing liquid reservoir for holding sufficient process liquid to form a liquid film covering the whole principal face of the substrate, a liquid film forming unit for forming the liquid film by supplying the process liquid onto the principal face of the substrate in a single burst, and a control unit for controlling the liquid film forming unit and the process liquid supply mechanism such that the process liquid is dispensed from the process liquid nozzle toward the principal face of the substrate after formation of the liquid film covering the whole area of the principal face of the substrate by the liquid film forming unit.
US08883029B2	Method of making a gas distribution member for a plasma processing chamber A method of making a Si containing gas distribution member for a semiconductor plasma processing chamber comprises forming a carbon member into an internal cavity structure of the Si containing gas distribution member. The method includes depositing Si containing material on the formed carbon member such that the Si containing material forms a shell around the formed carbon member. The Si containing shell is machined into the structure of the Si containing gas distribution member wherein the machining forms gas inlet and outlet holes exposing a portion of the formed carbon member in an interior region of the Si containing gas distribution member. The method includes removing the formed carbon member from the interior region of the Si containing gas distribution member with a gas that reacts with carbon, dissociating the carbon atoms, which may thereby be removed from the interior region of the Si containing gas distribution member leaving a shaped internal cavity in the interior region of the Si containing gas distribution member.
US08883027B2	Methods for removing a metal oxide from a substrate A method for generating plasma for removing metal oxide from a substrate is provided. The method includes providing a powered electrode assembly, which includes a powered electrode, a dielectric layer, and a wire mesh disposed between the powered electrode and the dielectric layer. The method also includes providing a grounded electrode assembly disposed opposite the powered electrode assembly to form a cavity wherein the plasma is generated. The wire mesh is shielded from the plasma by the dielectric layer when the plasma is present in the cavity, which has an outlet at one end for providing the plasma to remove the metal oxide. The method further includes introducing at least one inert gas and at least one process gas into the cavity. The method yet also includes applying an rf field to the cavity using the powered electrode to generate the plasma from the inert and the process gas.
US08883022B2	Mask blank and method of manufacturing an imprinting mold Provided is a mask blank which is used for manufacturing an imprinting mold and which may form a fine mold pattern with high pattern accuracy. A mask blank (10) includes a transparent substrate (1) and a thin film (2) contacted with a surface of the substrate. The thin film (2) includes a laminated film including an upper layer (4) which is composed of a material containing silicon (Si) or a material containing tantalum (Ta), and a lower layer (3) which is composed of a material containing at least one of hafnium (Hf) and zirconium (Zr) and containing substantially no oxygen.
US08883021B2	MEMS nanostructures and methods of forming the same A method of forming of MEMS nanostructures includes a portion of a substrate is recessed to form a plurality of mesas in the substrate. Each of the plurality of mesas has a top surface and a sidewall surface. A light reflecting layer is deposited over the substrate thereby covering the top surface and the sidewall surface of each mesa. A protection layer is formed over the light reflecting layer. An ARC layer is formed over the protection layer. An opening in a photo resist layer is formed over the ARC layer over each mesa. A portion of the ARC layer, the protection layer and the light reflecting layer are removed through the opening to expose the top surface of each mesa. The photo resist layer and the ARC layer over the top surface of each mesa are removed.
US08883020B2	Achieving greater planarity between upper surfaces of a layer and a conductive structure residing therein Greater planarity is achieved between surfaces of a conductive structure and a layer within which the conductive structure resides. A portion of the conductive structure protruding above the surface of the layer is selectively oxidized, at least in part, to form an oxidized portion. The oxidized portion is then removed, at least partially, to facilitate achieving greater planarity. The protruding portions may optionally be formed by selectively disposing conductive material over the conductive structure, when that the conductive structure is initially recessed below the surface of the layer. A further embodiment includes selectively oxidizing a portion of the conductive structure below the surface of the layer, removing at least some of the oxidized portion so that an upper surface of the conductive structure is below the upper surface of the layer, and planarizing the upper surface of the layer to the upper surface of the conductive structure.
US08883019B2	Method for manufacturing adjustable lens The present invention provides method steps for manufacturing an assembly of adjustable lenses on a wafer. The method steps provide an easy manufacturing of such lenses, minimizing the cost of assembly, and at the same time provide a solution for mass production of compact adjustable lenses for use in mobile phones, etc.
US08883018B2	Low-loss, wide-band grating coupler and method of making same A method for fabricating a grating coupler having a bottom mirror in a semiconductor wafer including etching a trench from a top surface of a wafer and around a grating coupler formed in the wafer; etching a void underneath the grating coupler; etching a via into the void from the backside of the wafer; and depositing a mirror on the bottom of the grating coupler. Alternatively, additional oxide may be deposited on the bottom of the grating coupler prior to the deposition of the mirror such that a desirable oxide thickness on the bottom is achieved.
US08883012B2	Reduced fouling of reverse osmosis membranes The present invention provides a new water purification method and system using reverse osmosis. In particular, the present invention provides methods and water purification systems using an ion exchange resin and absorbent media for pretreatment of water being fed to a reverse osmosis treatment system, where the pretreatment reduces fouling of, or deposits or chemical attack on the membrane surfaces and passageways. Particularly, a macroporous resin having an average pore diameter in the range of 1,000 to 500,000 Angstroms and a crush strength or Chatillon value of at least 24 g/bead (710 μm bead diameter) is used.
US08883010B2	Polymer composition with phytochemical and dialysis membrane formed from the polymer composition A biocompatible polymer composition which includes a matrix material and at least one of an isoflavone and a flavone at least partially dispersed in the matrix material is suited to use in a membrane for hemodialysis and other in vivo and in vitro applications.
US08883009B2	Water treatment A process for the treatment of water comprising at least the steps of: (a) providing the water in laminar flow; and (b) providing bubblefree aeration to the water. The present invention introduces aerobic treatment into wastewater settlement without any hindrance to the settlement process. The present invention is useable for any settlement step or stage, without limitation, the commonest being primary settlement or final settling.
US08883006B2	Fluid treatment system A fluid treatment system for treating feed water includes a first tubular member having first and second ends, at least one second tubular member having first and second ends, a pump positioned within the first tubular member, a filtering membrane positioned within the second tubular member, a first end cap for receiving the first ends of the first and second tubular members, and a second end cap for receiving the second ends of the first and second tubular members.
US08883004B2	Filter assembly A filter assembly includes a disposable filter body and a central support for the disposable filter body. Openings are provided in upper and lower ends of the disposable filter body for receiving a respective end of the central support. The filter assembly also includes a disposable filter cartridge, housed within the disposable filter body, and housing a filter member for filtering particulate contaminates from a flow of fluid through the filter assembly. The filter member is hollow and the disposable filter cartridge also includes an impermeable wall that extends axially through the filter member. The central support is separable from the disposable filter body and removable from the openings to allow disposal and replacement of the filter body and the filter cartridge during servicing.
US08882999B2	Cleaning assembly for use in fluid filtration systems Cleaning assemblies and particulate tolerant fluid bearings that are particularly well suited for use in centrifugal separation enhanced filtration devices are described. In one aspect of the invention, at least one bearing is arranged to carry a circulating cleaning assembly such that the cleaning assembly can rotate around a filter membrane during filtering operation of the filtration device. The bearing is preferably arranged to maintain the circulating cleaning assembly in a substantially coaxial alignment with the filter membrane and in a substantially stable longitudinal position relative to the filter membrane as the circulating cleaning assembly is rotated around the filter membrane. In another aspect of the invention a variety of particulate tolerant bearings are described.
US08882995B2	Process for predicting and reducing the corrosivity of a hydrocarbonaceous mixture Process for reducing the concentration of water-soluble carboxylic acids in a hydrocarbonaceous mixture which process comprises (i) taking a sample from the hydrocarbonaceous mixture and extracting the water-soluble carboxylic acids from the sample, (ii) subjecting the extracted water-soluble carboxylic acids to chromatography, (iii) calculating the concentration of water-soluble carboxylic acids in the hydrocarbon mixture based on the chromatography results, and (iv) reducing the concentration of water-soluble carboxylic acids in the hydrocarbonaceous mixture.
US08882994B2	Counter-current catalyst flow with split feed and two reactor train processing A process is presented for the increasing the yields of aromatics from reforming a hydrocarbon feedstream. The process includes splitting a naphtha feedstream into a light hydrocarbon stream, and a heavier stream having a relatively rich concentration of naphthenes. The heavy stream is reformed to convert the naphthenes to aromatics and the resulting product stream is further reformed with the light hydrocarbon stream to increase the aromatics yields. The process includes passing a catalyst stream in a counter-current flow relative to the hydrocarbon process stream.
US08882988B2	Potentiometric device and method selective for pioglitazone The potentiometric device and method selective for pioglitazone relates to the detection of pioglitazone in urine, in other liquid biological samples, and in pharmaceutical preparations for quality control testing and the like, and particularly to the use of a potentiometric sensor for potentiometric detection and measurement of the concentration of pioglitazone. The potentiometric sensor includes a plasticized polyvinyl chloride (PVC) matrix membrane having an ionophore impregnated or embedded therein. The ionophore is an iodobismuth anion in which the iodobismuth anion forms a complex with pioglitazone. The polymer membrane is plasticized with either ortho-nitrophenyl octyl ether (NPOE) or dioctyl phthalate (DOP).
US08882987B2	Biosensor measurement system and method for detecting abnormal waveform in biosensor A biosensor measurement system and a method for detecting abnormal measurement in a biosensor, which can significantly enhance the measurement precision without depending on the user's operation manner or the like, can be provided. A voltage application pattern for applying a voltage to a working electrode, a counter electrode, and a detection electrode has a halt period between a first application period and a second application period, and a reduction current measurement value obtained in the first application period is compared with a reduction current measurement value obtained in the second application period, and the measurement values are not outputted when a difference between the measurement values is outside a predetermined range.
US08882985B2	Perchlorate removal from concentrated salt solutions using amphoteric ion-exchange resins A process for reducing the concentration of perchlorate in an aqueous concentrated multi-component salt solution comprising treating the salt solution with an amphoteric ion-exchange resin to provide an adsorbed perchlorate and multi anion-containing resin and a perchlorate depleted solution; and removing the perchlorate depleted solution. The multi-anion are selected from chloride, chlorate, perchlorate, sulphate, and dichromate, present in electrolytic processes for the production of sodium chlorate.
US08882982B2	System and instrument for processing biological samples and manipulating liquids having biological samples A biological sample processing system comprises a container for large volume processing, a flat polymer film having a lower surface and a hydrophobic upper surface, which is kept at a distance d to the base side of the container by the protrusions. The distance d defines at least one gap when the container is positioned on the film. A liquid droplet manipulation instrument comprises at least one electrode array for inducing liquid droplet movements; a substrate supporting the at least one electrode array; and a control unit is characterized in that the container and the film are reversibly attached to the liquid droplet manipulation instrument. The system thus enables displacement of at least one liquid droplet from the at least one well through the channel of the container onto the hydrophobic upper surface of the flat polymer film and above the at least one electrode array; wherein the liquid droplet manipulation instrument controls a guided movement of the liquid droplet on the hydrophobic upper surface of the flat polymer film by electrowetting and to process there the biological sample.
US08882978B2	FAD-conjugated glucose dehydrogenase gene Disclosed herein are a gene (polynucleotide) encoding an FAD-conjugated glucose dehydrogenase which can be characterized by reactivity to glucose, thermal stability, substrate-recognition performance, and low activity for maltose; a process for the production of the enzyme using a transformant cell transfected with the gene; a method for the determination of glucose; a reagent composition for use in the determination of glucose; and a biosensor for use in the determination of glucose. An embodiment is a polynucleotide encoding an FAD-conjugated glucose dehydrogenase, comprising a polypeptide whose amino acid sequence comprises X1-X2-X3-X4-X5-X6, wherein X1 and X2 independently represent an aliphatic amino acid residue; X3 and X6 independently represent a branched amino acid residue; and X4 and X5 independently represent a heterocyclic amino acid residue or an aromatic amino acid residue.
US08882975B2	Sb-Te base alloy sinter sputtering target Provided is an Sb—Te base alloy sinter sputtering target having Sb and Te as its primary component and comprising a structure in which Sb—Te base alloy particles are surrounded by fine carbon or boron particles; wherein, if the mean diameter of the Sb—Te base alloy particles is X and the particle size of carbon or boron is Y, Y/X is within the range of 1/10 to 1/10000. The present invention seeks to improve the Sb—Te base alloy sputtering target structure, inhibit the generation of cracks in the sintered target, and prevent the generation of arcing during the sputtering process.
US08882973B2	Cathode power distribution system and method of using the same for power distribution Embodiments include a cathode power distribution system and/or method of using the same for power distribution. The cathode power distribution system includes a plurality of cathode assemblies. Each cathode assembly of the plurality of cathode assemblies includes a plurality of cathode rods. The system also includes a plurality of bus bars configured to distribute current to each of the plurality of cathode assemblies. The plurality of bus bars include a first bus bar configured to distribute the current to first ends of the plurality of cathode assemblies and a second bus bar configured to distribute the current to second ends of the plurality of cathode assemblies.
US08882968B1	Method and apparatus for solar desalination Method and apparatus for desalinization wherein a heating grid containing a fluid is used to heat the fluid to a vaporized state using energy provided by compound magnifying lens focusing solar energy directly onto the grid wherein the vapor from the grid system is transmitted to a steam turbine wherein electricity is generated to charge a battery while the vapor from the steam turbine is conducted to a condenser wherein the vapor is cooled and fresh water is provided from the condensate. The remaining fluid from the condenser is pumped back into a reservoir for storage while waiting to be conducted into the heating grid. The magnifying lens and grid is rotated for alignment with the sun.
US08882960B2	Substrate treating apparatus and substrate treating method An etchant is stored in a treating tank; a glass substrate is transported with transport rollers into the treating tank; the etchant is discharged from below the substrate to raise the substrate to a position above the transport rollers and below the surface of the etchant; the discharge of the etching liquid is stopped and the glass substrate is lowered to a position for contacting the transport rollers; the etchant is drained from the treating tank; and the glass substrate is unloaded with the transport rollers out of the treating tank. The disclosed method and apparatus can treat both front and back surfaces of the substrate uniformly.
US08882959B2	System and method for applying tape to a surface A tape-dispensing apparatus may include a removable part and a base part.
US08882958B2	Device and method for welding profiled parts The invention relates to a device for welding profiled parts (8), in particular plastics profiled parts, having at least one welding head (1) that can be positioned in a predetermined or predeterminable target welding position (6) relative to another welding head (1, 9) and/or relative to a holding device. According to the invention the welding head (1) and/or a part of the welding head (1), that comprises at least one heating element, such as a heating plate, for melting the profiled parts, can be positioned and/or is movable in accordance with at least one dimensional variation of at least one of the profiled parts (8) from a target dimension in a spatial tolerance range (5) around the target welding position (6).
US08882957B2	Methods of manufacturing paint roller covers from a tubular fabric sleeve A method of manufacturing paint roller covers is disclosed in which the paint roller covers are manufactured from a seamless segment of tubular paint roller cover fabric that is placed onto a cylindrical forming tube having a segment of bonding material temporarily secured on its outer surface under the segment of tubular paint roller cover fabric. The cylindrical forming tube is placed on a heated mandrel to apply heat thereto to cause the bonding material to bond to the interior of the segment of tubular paint roller cover fabric. The cylindrical forming tube is removed from the mandrel and cooled, and the segment of tubular paint roller cover fabric becomes secured to the bonding material to produce a semi-rigid paint roller cover segment. The semi-rigid paint roller cover segment may be finished into paint roller covers.
US08882956B2	Composite structures using interpenetrating polymer network adhesives An interpenetrating polymer network (IPN) adhesive comprises an acrylated polymer system curable by radiation, and a flexible epoxy system thermally curable after the acrylated polymer system is cured.
US08882954B2	Method of manufacturing rigid-flexible printed circuit board The present invention relates to a method of manufacturing a rigid-flexible printed circuit board including: providing a first flexible film having a first metal layer on one or both surfaces; forming a circuit pattern by patterning the first metal layer; forming a second flexible film, which has a second metal layer on one surface, on one or both surfaces of the first flexible film; forming a circuit pattern by patterning the second metal layer in a rigid domain R; providing an anti-oxidation protective layer on the second metal layer in a flexible domain F; laminating at least one circuit layer on the second flexible film; and removing the circuit layer in the flexible domain F.
US08882953B2	Method for fabricating cliché, and method for forming thin film pattern by using the same Disclosed is a method for fabricating a cliché that can prevent formation of a defective thin film pattern, and a method for forming a thin film pattern using the same. The method for fabricating a cliché includes providing a base substrate having first and second regions, forming a first depressed pattern having a first depth and a first width at a first region, and a second depressed pattern having a second width greater than the first width and a depth the same with the first depth at a second region, forming a protective film for exposing the second region and covering the first region, the protective film having adhesivity, forming the second depressed pattern to have a second depth deeper than the first depth of the first depressed pattern at the first region by using the protective film having the adhesivity, and removing the protective film.
US08882949B2	Tubular body and manufacturing method thereof A manufacturing method of the present invention includes the steps of: winding a fiber reinforced resin member containing a fiber and a matrix resin around a mandrel to obtain an intermediate formed body; winding a wrapping tape around the intermediate formed body with an application of a tension; heating the intermediate formed body to cure the matrix resin; and pulling the mandrel out and removing the wrapping tape after the step of heating to obtain a cured tubular body. A base polymer of a base material of the wrapping tape is a polyolefin resin and/or a polyester resin. The step of heating includes: a first heating stage for heating the intermediate formed body at a temperature of 70° C. or higher and 90° C. or lower for a time of 120 minutes or longer and 4320 minutes or shorter; and a second heating stage for heating the intermediate formed body at a temperature of 120° C. or higher and 200° C. or lower for a time of 5 minutes or longer and 20 minutes or shorter after the first heating stage.
US08882948B2	Glove manufacturing method and manufacturing apparatus, and glove manufactured by the method or the apparatus In a glove manufacturing device, a glove insert with thermoplastic adhesive applied on the outer side is fixed on a glove holding member in a state where it has been inserted into the inner side of the outer material of the glove. The glove insert is then expanded by way of a gas injection means, and the outer material of the glove and the glove insert are bonded. The glove holding member is fixed on the turntable and sent to a heating furnace by this rotating.
US08882945B2	Isobutylene (co)polymeric adhesive composition Adhesive compositions are described comprising a) a non-functional isobutylene (co)polymer, b) an amine-functional poly(isobutylene) polymer, optionally an acid-functional (meth)acrylate copolymer, and optionally a tackifier.
US08882942B2	Ni-added steel plate and method of manufacturing the same A Ni-added steel plate contains, by mass %, C: 0.03% to 0.10%, Si: 0.02% to 0.40%, Mn: 0.3% to 1.2%, Ni: 5.0% to 7.5%, Cr: 0.4% to 1.5%, Mo: 0.02% to 0.4%, Al: 0.01% to 0.08%, T.O: 0.0001% to 0.0050%, P: limited to 0.0100% or less, S: limited to 0.0035% or less, and N: limited to 0.0070% or less with a remainder composed of Fe and inevitable impurities, in which a Ni segregation ratio at a position of ¼ of a plate thickness away from a plate surface in a thickness direction is 1.3 or less, a fraction of austenite after deep cooling is 2% or more, an austenite unevenness index after deep cooling is 5.0 or less, and an average equivalent circle diameter of austenite after deep cooling is 1 μm or less.
US08882938B2	High strength hot dip galvanised steel strip A high strength hot dip galvanized steel strip including, in mass percent, of the following elements: 0.10-0.18% C, 1.90-2.50% Mn, 0.30-0.50% Si, 0.50-0.70% Al, 0.10-0.50% Cr, 0.001-0.10% P, 0.01-0.05% Nb, max 0.004% Ca, max 0.05% S, max 0.007% N, and optionally at least one of the following elements: 0.005-0.50% Ti, 0.005-0.50% V, 0.005-0.50% Mo, 0.005-0.50% Ni, 0.005-0.50% Cu, max 0.005% B, the balance Fe and inevitable impurities, wherein 0.80%2.10%. This steel offers improved formability at a high strength, has a good weldability and surface quality together with a good produce-ability and coat-ability.
US08882936B2	High-tensile steel with excellent weldability and toughness and with tensile strength of 550 MPa class or more and method of production of the same The present invention provides a high-tensile steel material having a tensile strength of the 550 MPa class or more which can simultaneously raise the strength and toughness of the heat affected zone of weld to equal those of the matrix and a method of production of the same, that is, a high-tensile steel material with excellent weldability and toughness and with tensile strength of the 550 MPa class or more containing, by mass %, C: 0.005 to 0.10%, W: 0.10 to 3.0%, Nb: 0.010 to 0.080%, and V: 0.010 to 0.50%, limiting the Ti to less than 0.005%, satisfying equation; EC=2[C]−[Nb]/9−[V]/12>0.020, having an amount of precipitation of W contained in the steel material, in terms of analytical value obtained by quantitative analysis of potential electrolysis extraction residue by fluorescent X-ray analysis, of 0.0050% or less, and having 60% or more of its structural composition in a cross-section of the steel as a bainite structure.
US08882935B2	Fabrication of nonpolar indium gallium nitride thin films, heterostructures, and devices by metalorganic chemical vapor deposition A method for the fabrication of nonpolar indium gallium nitride (InGaN) films as well as nonpolar InGaN-containing device structures using metalorganic chemical vapor deposition (MOVCD). The method is used to fabricate nonpolar InGaN/GaN violet and near-ultraviolet light emitting diodes and laser diodes.
US08882932B2	Methods and compositions for the removal of starch A method of warewashing for the removal of starch is described herein. The method includes applying an alkaline composition to a dish, then applying an acidic composition to a dish, and then applying a second alkaline composition to the dish. The method may include additional steps. Compositions for using with the method are also disclosed. Finally, dish machines that may be used in accordance with the method are disclosed.
US08882931B2	Water-conducting household appliance A water-conducting household machine, specifically a dishwasher, includes a compartment having a closable compartment opening, and at least one washing device for generating at least one water jet in the compartment. At least one baffle plate is disposed on an inner side of the compartment in at least one area of impact of the water jet and in such a way as to be vibration-free for noise reduction, particularly for noise damping and/or sound insulation.
US08882928B2	Method for controlling dishwasher Provided is a method of controlling a dishwasher. The dishwasher includes a washing chamber accommodating a dish, a sump storing washing water, and supplying the washing water to the washing chamber, and a filter part provided to the sump, and filtering a foreign substance from the washing water. In the method, a first pump is driven to perform a washing or rinsing process, the first pump is stopped and a second pump is driven for a first set time to perform a discharging process, after the washing or rinsing process, the second pump is stopped and the first pump is driven for a second set time, and the first and second pumps are stopped.
US08882927B2	Windshield wiper de-icing Methods and apparatus are provided for vehicle windshield washing-wiping and wiper de-icing. Primary nozzles provide washing fluid to the windshield during normal operations and secondary nozzles bathe the wiper arms with washing fluid to de-ice the wipers during a de-icing mode. Washing fluid is drawn from a reservoir and delivered to the nozzles by a pump. When the outside air temperature T is greater than Tc, the critical temperature for ice formation, the wipers and washing-wiping proceed normally with washing fluid delivered to the primary nozzles for windshield washing. When T≦Tc and the wipers are not moving, a washer fluid supply line valve delivers washing fluid to the secondary nozzles to de-ice the wipers. The wiper motor, washing fluid pump and valve are operated by a controller based on inputs from wiper position and air temperature sensors, using predetermined information stored in on-board memory.
US08882926B2	Removal of residual particulate matter from filter media A method for removing residual filter cakes that remain adhered to a filter after typical particulate removal methodologies have been employed, such as pulse-jet filter element cleaning, for all cleanable filters used for air pollution control, dust control, or powder control.
US08882922B2	Organic layer deposition apparatus An organic layer deposition apparatus capable of reducing or minimizing shifting of a pattern, caused when a patterning slit sheet sags.
US08882917B1	Substrate processing including correction for deposition location Substrate processing including correction for deposition location is described, including a combinatorial processing chamber that incorporates the correction. The combinatorial processing chamber can be used to process multiple regions of a substrate using different processing parameters on different regions. For example, one region can have one material deposited on it and another region can have a different material deposited on it, although other combinations and variations are possible. The combinatorial processing chamber uses a rotating and revolving substrate pedestal to be able to deposit on all locations or positions on a substrate. The combinatorial processing chamber uses a correction factor that accounts for variations in alignment and/or configuration of the processing chamber so that the actual location of deposition of a region is approximately the same as a desired location of deposition.
US08882908B2	Reverting colored concrete and rinse water to gray A simple and easily useable system for reverting an uncured colored concrete material back to a gray color, by merely determining the original pigment and loading initially used to color the concrete material. The system utilizes a collection of pigment mixtures that can be selected and combined as needed to revert virtually any colored concrete back to a gray color, thus eliminating or reducing the expulsion of non-gray or colored concrete and/or dirty rinse water. Additionally, the volume of rinse water needed to clean out gray concrete is significantly less than that needed to clean out colored concrete.
US08882899B2	Method and plant for producing asphalt mixture The invention relates to a method and a plant for producing asphalt mixture and is directed in particular to the recycling of recovered asphalt. In order to achieve recycling of up to 100% recovered asphalt and to produce an asphalt mixture with the required quality, it is provided according to the invention that at least the drying and heating of the asphalt granulate and/or aggregates are carried out in a low oxygen atmosphere. The low oxygen atmosphere is achieved by supplying low oxygen gases with an oxygen content of maximum 10%, preferably with an oxygen content of maximum 5%. The conveyance of the heated and dried asphalt granulate and/or aggregates, the siloing and mixing with bitumen to form a new, incorporation-ready asphalt mixture also usefully take place in a low oxygen atmosphere.
US08882895B2	Method of controlling airflow through a water recovery device A system and method recover water from an ambient airstream. Dehumidification of the airstream is also achieved by removal of the water. A device of the system includes a chamber having a group of trays that hold respective amounts of liquid desiccant in each tray. A foam media absorbs the desiccant to increase an exposed surface of the desiccant to the airstream. Fans and valves are used to dynamically control airflow through the device. A charge cycle circulates air through the device to remove water vapor from the airstream. A subsequent extraction cycle removes water collected in the liquid desiccant by a condenser communicating with the chamber. An integral heat exchanger adds heat to the chamber during the extraction cycle. A controller is used to integrate and manage all system functions and input variables to achieve a high efficiency of operational energy use for water collection.
US08882894B2	Vaporisation injector The invention relates to a vaporization injector for a gas chromatograph, said injector comprising a structure (11) mounted in a detachable manner on the gas chromatograph body and including the sample introduction means, the vaporization chamber and pneumatic connections for feeding the carrier gas to the vaporization chamber and to the septum purge means, as well as pneumatic connections for evacuating the splitted sample and carrier gases.
US08882893B2	Method for cleaning a gas flow loaded with dust A method is provided for cleaning a gas flow made of top gas and/or off gas and/or export gas from a direct reduction plant or a melt reduction plant, which is loaded with dust and/or fine particulate solids. The gas flow is subjected to a dry cleaning using at least one dry filter, wherein dusts and/or fine particulate raw materials are separated from the gas flow. The cleaned gas flow is fed into a CO2 separating device, wherein CO2 is separated, forming a product gas that is substantially free of water and CO2 and is used for backflushing the dry filter.
US08882891B1	Vented gas drilling fluid catch apparatus The present invention is directed to a catch tank for drilling operations. The catch tank is located between a mud-gas separator and a flare. The catch tank has an inlet port with a closed end baffle which allows a drilling fluid-gas mixture to be separated and gas to proceed to the flare without entrained drilling fluid.
US08882884B2	Systems and methods for optimizing a PAC ratio An exemplary embodiment of the present invention provides a method of controlling a PAC-to-particulate ratio in a potion of an exhaust system from a furnace. The method comprises measuring a second amount of particulate exiting a particulate removal system, and controlling a first amount of particulate removed by the particulate removal system based in part on the measured second amount of particulate, such that a desired ratio of PAC-to-particulate is obtained in the portion of the exhaust system.
US08882881B2	Method for concentrating and recovering precious metals from spent mobile phone PCBS and spent auto-catalysts using waste nonferrous slag The present invention relates to a method of concentrating and recovering precious metals from waste mobile phone PCBs and spent automotive catalysts using waste nonferrous slag, in which precious metals such as gold, silver, platinum, palladium or rhodium can be concentrated and recovered by simultaneously treating different industrial wastes, including waste nonferrous slag, waste mobile phone PCBs and spent automotive catalysts, and industrial waste can be recycled as resources. According to the present invention, it is possible to maximize the utilization ratio of precious metal resources that totally depend on the import in terms of the domestic situation of a poor-natural resources country. In addition, the industrial waste can widely be utilized for the recovery of precious metals in the fields of household appliance recycling and electronic part manufacture, and the recycling of industrial by-products discharged in the field of non-ferrous refinery.
US08882870B2	Coated tool A coated tool has a substrate and a coating film coated on the surface thereof. The coating film includes an intermediate film coated on the surface of the substrate, and an oxide film coated on the surface of the intermediate film. A crack coefficient R obtained by measuring a crack length dc (μm) which is generated on the surface of the coated tool by pushing a Vickers indenter into the surface of the coating film with an applied load P=196(N), and a fracture toughness KIC (MPa·m0.5) of the substrate, and by calculating from the following numerical formula: R=P/(dc·KIC), is 0.07 to 0.12 m0.5.
US08882869B2	Methods of forming polycrystalline elements and structures formed by such methods Methods of forming a polycrystalline element comprise forming a polycrystalline table on a first substrate. Catalyst material may be removed from at least a portion of the polycrystalline table. The polycrystalline table and a portion of a first substrate attached to the polycrystalline table may be removed from a remainder of the first substrate. The portion of the first substrate may be attached to another substrate. Polycrystalline elements comprise a polycrystalline table attached to a portion of a first substrate on which the polycrystalline table was formed another substrate attached to the portion of the first substrate.
US08882868B2	Abrasive slicing tool for electronics industry A bond matrix for metal bonded abrasive tools includes a metal bond system, porosity and an optional filler. Tools according to embodiments of the invention exhibit long tool life, produce an acceptable quality of cut and can have self-dressing properties. The bond matrix can be used, for example, in abrasives tools configured for the electronics industry, such as 1A8 wheels for slicing ball grid arrays (BGAs) and other such slicing operations.
US08882860B2	Emulsifier for water-in-oil emulsion fuel An emulsifier for a water-in-oil (W/O) emulsion fuel wherein reseparation between oil and water does not take place for a long period of time because of a stable emulsion state with homogenous dispersion. The emulsifier for a water-in-oil emulsion fuel includes the following (1) to (7) components: (1) heavy oil A: 50 mL or more 100 mL, (2) heavy oil B: 100 mL or more 200 mL, (3) heavy oil C: 300 mL or more 450 mL, (4) methanol: 100 mL or more 150 mL, (5) ethanol: 100 mL or more 200 mL, (6) palm oil: 100 mL or more 150 mL, and (7) water: 100 mL or more 200 mL.
US08882850B2	Multi-formed collagenous biomaterial medical device A collagenous biomaterial medical device comprising a molded sponge material formed from comminuted submucosa fragments that have not been cross-linked with a cross-linking agent, wherein said submucosa has at least one biotropic agent, and wherein said biotropic agent is a growth factor is disclosed.
US08882847B2	Patient selectable knee joint arthroplasty devices Disclosed herein are methods and devices for repairing articular surfaces in a knee joint. The articular surface repairs are customizable or highly selectable for each patient and geared toward providing optimal fit and function. Kits are also provided to enable customized repairs to be performed.
US08882846B1	Surgical process for affixing an elbow implant into the ulna A surgical process for affixing an elbow implant into the ulna has the steps of separating the olecranon process from the ulna so as to expose an end of an intermedullary canal of the ulna, inserting a stem of the elbow implanted into the intermedullary canal such that an end of the stem extends outwardly of the end of the ulna, and affixing the olecranon process onto the exposed end of the ulna. A hole is drilled through the olecranon process such that the hole is axially aligned with the intermedullary canal of the ulna. This hole is drilled prior to the step of separating.
US08882843B2	Interbody spinal fusion implant having a trailing end with at least one stabilization element A flanged interbody spinal fusion implant for insertion at least in part between adjacent vertebral bodies has opposed upper and lower surfaces adapted to contact each of the adjacent vertebral bodies from within the disc space, a leading end for insertion between the adjacent vertebral bodies, and a trailing end opposite the leading end. The trailing end has a height greater than the maximum height of the disc space forming a flanged portion adapted to overlie a part of the anterior aspects of the vertebral bodies adjacent and proximate the disc space to be fused. The flanged portion has at least two bone screw receiving holes, at least one each adapted to overlie each of the adjacent vertebral bodies at least in part. The implant has at least one locking element to lock one or more of the bone screws inserted in the bone screw receiving holes. Instrumentation for inserting the implant, forming screw holes in the vertebral body, and for locking the locking elements are disclosed.
US08882842B2	Modular prostheses and method for the implantation of modular prostheses A method of implanting an intervertebral disk prosthesis, and a modular intervertebral disk prosthesis. The method includes permanently anchoring at least one apposition plate with respective vertebra bodies and detachably connecting an intermediate module with the apposition plate such that the intermediate module can be removed and replaced postoperatively. The modular prosthesis includes at least one apposition plate configured to be permanently implanted, and an intermediate module configured to be detachably secure to the apposition plate.
US08882841B2	Steerable interbody fusion cage An interbody vertebral cage facilitates minimally invasive approaches to the intervertebral disc for corrective restoration of disc height, stabilization between vertebra, and fusion. The preferred embodiment provides a streamlined, slender straight contour with a central hinge or other articulating apparatus that allows the introduction of the cage into the operative field and disc space in a minimally invasive, bone-sparing manner. After partial insertion, the hinge component is activated, allowing the operator to steer the cage anterior-medially within the disc space to an anterior-central position within the intervertebral space. In this state the cage is shaped like a crescent, chevron or boomerang.
US08882840B2	Expandable vertebral device with cam lock An expandable cage supports adjacent vertebra in spine surgery. The expandable cage includes a first supporting member configured to engage tissue and a second supporting member operatively associated with the first supporting member. The first and second supporting members are movable relative to each other. The expandable cage further includes a cam lock mechanism configured to maintain the first and second supporting members in a fixed relative position. In another embodiment, the expandable cage includes a ring plate lock mechanism in lieu of the cam lock mechanism. The ring plate lock mechanism is adapted to maintain the first and second supporting members in a fixed relative position.
US08882837B2	High precision manufacture of polyurethane products such as spinal disc implants having gradual modulus variation A process for making a polymeric product having a gradual variation in modulus through at least a portion of the product is disclosed together with an artificial spinal disc formed using the process.
US08882835B2	Interbody spinal fusion implant having an anatomically conformed trailing end An interbody spinal fusion implant adapted for placement at least in part across an intervertebral space formed across a disc space between two adjacent vertebral bodies and for penetrating engagement into each of those vertebral bodies, the implant having a trailing end adapted to sit upon and not protrude from the anterolateral peripheral rim of bone of the vertebral body.
US08882831B2	Collapsible/expandable prosthetic heart valves with non-expanding stent posts and retrieval features A frame structure for a collapsible and re-expandable prosthetic heart valve. The frame structure includes an annular annulus portion that is configured for implanting in or near a patient's native heart valve annulus. This annulus portion of the frame structure may include a plurality of annularly spaced commissure post structures interconnected by connecting structures. The commissure post structures may be more resistant to annular collapse than the connecting structures. In the case of a prosthetic aortic valve, the frame structure may also include an annular aortic portion. The aortic portion may include a plurality of attachment points (for tethers) closest to the annulus portion. Such attachment points and tethers can facilitate re-collapse of a partly deployed valve in the event of a need to reposition or remove the valve.
US08882830B2	Implantable devices for controlling the internal circumference of an anatomic orifice or lumen An implantable device for controlling the circumference of internal anatomic passages corrects physiologic dysfunctions resulting from a structural lumen which is either too large or too small. Implants are disclosed which employ various means for adjusting and maintaining the size of an orifice to which they are attached. Systems permit the implants to be implanted using minimally invasive procedures and permit final adjustments to the circumference of the implants after the resumption of normal flow of anatomic fluids in situ. Methods are disclosed for using the implants to treat heart valve abnormalities, gastroesophageal abnormalities, anal incontinence, and the like.
US08882829B2	Low profile improved radiopacity intraluminal medical device A stent or other intraluminal medical device having markers formed from housings integral with the stent and marker inserts having a higher radiopacity than the stent provides for more precise placement and post-procedural visualization in a vessel, by increasing the radiopacity of the stent under X-ray fluoroscopy. The housings are formed integral to the stent and the marker inserts are made from a material close in the galvanic series to the stent material and sized to substantially minimize the effect of galvanic corrosion. The housings are also shaped to minimize their impact on the overall profile of the stent.
US08882827B2	Stent The stent comprises a tubular body comprising a plurality of ring units arranged in the axis direction and bridged by a connecting element. Each of the units comprises a plurality of cells connected with each other, each of the cells having a U-shaped form comprising two linear parts and a circular arc part therebetween, and opening toward one end. The ring units comprise first and second units alternatively arranged and the oppositely disposed cells of the first and second units are only partly bridged by the connecting elements. The shapes of the cells of the first and second units are axisymmetrical about the connecting element. The curvature radius of the top of the arc constituting the arc part is 1.1 and 1.5 times larger than that of each of the tangent circles formed at the edges of two linear parts of the cell on the circular arc part side.
US08882826B2	Intravascular stent An expandable stent for implanting in a body lumen, such as a coronary artery, peripheral artery, or other body lumen. In one aspect, the stent includes a butterfly pattern to which connecting links are attached. In another aspect, the stent embodies a non-directional structure. One embodiment is a stent in which one or both ends are more flexible than the center portion. Also, the stent may have a non-uniform drug coating. Another embodiment relates to a stent having ends that are more radiopaque than the center portion.
US08882825B2	Stents including poly(L-lactide) formulations that minimize molecular weight drop during processing A stent scaffolding including a polymer formulation comprising PLLA and polymandelide is disclosed. The polymandelide reduces the molecular weight drop during processing, particularly during sterilization. The stent scaffolding can further include one or more additional stabilizing agents that additionally reduce the molecular weight drop during processing.
US08882823B2	Non-foreshortening intraluminal prosthesis An intraluminal prosthesis is provided with a plurality of annular elements. Each annular element includes a plurality of struts and apices connected to form an annular configuration. Each annular element has a compressed state and an expanded state, and has a longitudinal dimension which is smaller in the expanded state than in the compressed state. A plurality of connecting members connect the apices of adjacent annular elements. The connecting members have a plurality of alternating segments that function to compensate for the smaller longitudinal dimension of each annular element in the expanded state. The stent may be provided with varying flexibility along its length and/or circumference, and may include segments that have different diameters.
US08882814B2	Orthopedic plating assembly for bone fixation and subsidence In an exemplary embodiment, the present invention provides an orthopedic plating assembly for bone fixation that includes an orthopedic plate and orthopedic anchors that can accommodate subsidence in the vertebral bodies as well as prevent the anchors from “backing out” of their installed position. The assembly, in one embodiment, includes an orthopedic plate and at least one orthopedic anchor, the orthopedic anchor capable of rotating and translating with respect to the plate. The assembly further includes a first blocking member and a second blocking member, the blocking members cooperate to prevent the at least one orthopedic anchor from uninstalling from an installed position.
US08882810B2	Crossover spinous process implant A device intended for the treatment of spinal stenosis. This device is an inter-spinous spacer that is introduced through a single posterior incision. It uses a single piece insertion technique with a unilateral approach. The surgeon does not need to access the opposite side of the spinous process. It allows the user infinite adjustability in distraction height with a single locking mechanism.
US08882801B2	Dual thread cannulated suture anchor Methods and devices are provided for anchoring suture to bone. In one exemplary embodiment, a cannulated suture anchor is provided and it includes a suture-engaging member formed therein and configured to receive a suture therearound such that trailing ends of the suture can extend through the suture anchor. The suture anchor can also include at least a proximal portion having dual threads to facilitate engagement with bone. The present invention also provides exemplary sutures and drivers that can be used with the various methods and devices disclosed herein, or with other methods and devices known in the art.
US08882800B2	Medical instrument A medical instrument with a shank consisting of pivotable jaw parts and a handle, the two jaw parts of the tool are pivotable relative to each other independently via the handle and each of the pivotable jaw parts is actuated via a separate drive. One drive is designed as a grip part mounted pivotably on the handle and is connected to one jaw part via a first push/pull element mounted in an axially displaceable manner in the shank, and the other drive is an adjusting wheel rotatable about a longitudinal axis of the shank and is connected to the other jaw part of the tool via a second push/pull element mounted in an axially displaceable manner in the shank. The push/pull element is designed as a push/pull rod, and the push/pull element which is coupled to the adjusting wheel is designed as a push/pull tube coaxially surrounding the push/pull rod.
US08882798B2	Endoscopic tools for the removal of balloon-like intragastric devices A mechanism for removing a fluid-filled object such as an intragastric balloon from a patient. The apparatus includes a delivery tube having a lumen and a retrieval tool able to slide within the lumen that can both puncture and grasp the intragastric balloon. The retrieval tool may have sharpened graspers with either a sharp tip and/or knife-like edges. Alternatively, the delivery tube itself may have sharpened cutting blades that deploy outward to puncture the intragastric balloon. One embodiment utilizes a suction cup tip on the delivery sheath and a sharpened puncture rod that extends past the distal tip of the lumen, for rapid deflation of a balloon. Various embodiments hasten the deflation process and simplify the manipulation required by the surgeon.
US08882792B2	Ultrasonic surgical apparatus with silicon waveguide Ultrasound surgical apparatus are disclosed, including: medical ultrasound handpieces with proximally mounted ultrasound radiators configured to create a distally-focused beam of ultrasound energy, in combination with distal guide members for control of focal point depth; medical ultrasound handpieces with proximally mounted ultrasound radiators configured to create a distally-focused beam of ultrasound energy, in combination with distal rolling members for manipulability and control of focal point depth; medical ultrasound handpiece assemblies with coupled end effectors providing a probe with a probe dilation region configured to have an average outside diameter that is equal to or greater than the average outside diameter of a probe tip and neck; as well as junctions to an ultrasonically inactive probe sheath; medical ultrasound handpiece assemblies with coupled end effectors having positionable, ultrasonically inactive probe sheath ends slidably operable to both cover and expose at least a probe tip; and ultrasound transducer cores including a transducing structure affixed to a longitudinally elongated, generally planar, single crystal or polycrystalline material waveguide.
US08882785B2	Endoscopic suturing device An endoscopic suturing device that can be employed to suture tissue using endoscopic techniques to place one or more stitches in tissue during a single intubation of an endoscope. The suturing device may include a suturing capsule with a suction chamber that is configured to capture tissue that is to be sutured. A needle is movable along a pathway across the suction chamber to penetrate and place stitches in the captured tissue. A catch is located distal to the suction chamber to receive and retain the suture during a stitching sequence. The catch may be movable along the needle pathway and configured to release the suture when the catch moves a predetermined distance along the pathway. The catch may be configured so that a predetermined amount of force is required to move the catch the predetermined distance required to release the suture.
US08882782B2	Direct access atherectomy devices and methods of use An atherectomy device and method has cannula systems having lumens adapted for insertion of a blood filter and an atherectomy catheter useful for performing atherectomy directly on a patient's cardiovascular tissue. Other embodiments include a lumen for arterial perfusion useful in providing oxygenated blood to the aorta during cardiopulmonary bypass. The distal end of the atherectomy catheter includes an assembly that has a pincer, a loop with or without a mesh, laser, hydraulics, or other suitable mechanism adapted for removing atheroma from a cardiac or vascular tissue. Methods of using the systems for vascular atherectomy are also disclosed herein.
US08882781B2	Combined treatment for cataract and glaucoma treatment A method is provided for treatment of cataract in combination with a glaucoma procedure while maintaining the intraocular pressure by permitting aqueous to flow out of an anterior chamber of the eye through a surgically stented pathway. A trabecular stent is adapted for implantation within the trabecular meshwork of an eye such that intraocular liquid flows controllably from the anterior chamber of the eye to Schlemm's canal, bypassing the trabecular meshwork. Depending upon the specific treatment contemplated, pharmaceuticals may be utilized in conjunction with the trabecular stent enabling post-cataract healing processes.
US08882780B2	Methods and apparatus for determining pin placement during hip surgery New apparatuses and methods for their design and use are disclosed that can be used to assist a surgeon in placing a guide pin during hip surgery. Specifically, a hip surgery method is disclosed in which an image of a patient's femur can be obtained and used to design and prepare a mold that contains an aperture for guiding a drill at the desired location and angle. During surgery the mold can be quickly and accurately positioned on the exposed femur head. Then, a drill bit can be inserted through the aperture and an opening for a pin can be drilled into the femur head. The mold can have a unique contoured surface adapted to fit to the femur head in a single unique position such that the opening is made in a unique desired position. The apparatuses and methods facilitate faster, more accurate surgery and are less invasive.
US08882776B2	Extended articulation orthopaedic implant A kit for use in performing joint arthroplasty, the kit including a prosthesis to be fitted to a long bone and a cutting guide. The cutting guide including a housing having an attachment mechanism adapted to couple the housing to the bone during arthroplasty and a wall defining a continuous path and a blade for cutting the bone, the blade fitting within and sliding along the continuous path such that the blade cuts the bone in a shape matching the second body articulating surface.
US08882761B2	Catheter and method for improved ablation An ablation electrode is mounted on the distal end of a catheter with a first portion inside and a second portion outside the catheter. The second portion is adapted to have a surface that makes maximum contact with a tissue to be ablated, leaving a minimum area not covered by the tissue and potentially exposed to blood. The first portion is adapted to provide an extended surface area for efficient exchange of heat with a coolant flowing inside the catheter. Outlets provided near the area not covered by the tissue in the second portion prevents blood from getting close to or come directly in contact with the area, thereby greatly reducing formation of dangerous blood clots. The minimizing of an electrical circuit through blood greatly reduces wasted power into the electrode so that the efficiently cooled electrode is not burdened. The catheter preferably has multiple electrodes with similar features.
US08882760B2	Electrosurgical medical system and method A medical device system and method provide an RF electrosurgical generator coupled to an electrosurgical electrode via a patient box disposed in close proximity to the patient. An RF signal is delivered from the generator to the patient box where signal power is increased and the RF signal delivered to the electrosurgical electrode. The patient box is coupled to the electrosurgical electrode by a short cable capable of carrying an HV, high frequency 5 MHz signal without leakage. An electrical characteristic associated with the electrosurgical electrode is monitored and a desired RF power output and duty cycle maintained by adjusting DC input voltage applied to an RF amplifier, responsive to the monitoring. The system determines when the electrosurgical cutting electrode has started cutting and switches from a start mode to a run mode having a different RF duty cycle and a reduced RF power output controlled by a servo system.
US08882755B2	Electrosurgical device for treatment of tissue A novel medical probe assembly, system, and methods for the use thereof to treat tissue are described. The system optionally comprises an energy source, two probe assemblies, and one or more cooling devices to provide cooling to at least one of the probe assemblies. The probe assemblies may be configured in a bipolar mode, whereby current flows preferentially between the probe assemblies. The probe assemblies and system described herein are particularly useful to deliver radio frequency energy to a patient's body. RF energy delivery may be used for various applications, including the treatment of pain, tumor ablation and cardiac ablation.
US08882753B2	Devices and methods for percutaneous energy delivery The invention provides a system and method for percutaneous energy delivery in an effective, manner using one or more probes. Additional variations of the system include array of probes configured to minimize the energy required to produce the desired effect.
US08882749B2	Tissue-anchored devices A therapeutic or diagnostic device is provided. The device includes a device body which is positionable within a lumen or passageway within a body and a tether which is attachable at a first end to the device body and at a second end to a tissue region not anatomically associated with the lumen or passageway.
US08882748B2	Transmucosal drug delivery device and method including chemical permeation enhancers Devices and methods are provided for transmucosal drug delivery. The transmucosal drug delivery device may include a housing configured for intralumenal deployment, such as intravaginally, into a human or animal subject; a drug-dispensing portion which contains at least one drug, the drug-dispensing portion being configured to dispense the drug from the housing by positive displacement; and a permeability enhancer-dispensing portion configured to release or generate a permeability enhancing substance to disrupt at least one region of a mucosal barrier adjacent to the housing at a selected time while intralumenally deployed in the human or animal subject. The device may be operable to dispense the drug from the housing to a region of the mucosal barrier disrupted by the permeability enhancing substance.
US08882747B2	Substance delivery system Embodiments of a system including a remotely controlled substance delivery device and associated controller are described. Methods of use and control of the device are also disclosed. According to some embodiments, a delivery device or related device may be placed in an environment in order to pump a material into the environment or into an additional fluid handling structure within the device. Exemplary environments include a body of an organism, a body of water, or an enclosed volume of a fluid. The concentration of a substance in the fluid to be delivered may be modified by a remote control signal. In selected embodiments, a magnetic field, an electric field, or electromagnetic control signal may be used.
US08882746B2	Wound cleansing apparatus with scaffold An apparatus for cleansing and applying therapy or prophylaxis to wounds, in which irrigant fluid containing a physiologically active material from a reservoir connected to a conformable wound dressing and wound exudate from the dressing are recirculated by a device for moving fluid through a flow path which passes through the dressing and a means for fluid cleansing and back to the dressing. A biodegradable scaffold underlies the dressing on the wound bed to promote tissue growth. The cleansing means (which may be a single-phase, e.g. micro-filtration, system or a two-phase, e.g. dialytic system) removes materials deleterious to wound healing, and the cleansed fluid, still containing materials that are beneficial in promoting wound healing, is returned to the wound bed. The dressing, an assembly comprising the dressing and scaffold, and a method of treatment using the apparatus.
US08882738B2	Locking vial adaptors and methods In certain embodiments, a vial adaptor for removing liquid contents from a vial comprises a piercing member and a bag. The bag can be contained within the piercing member such that the bag is introduced to the vial when the vial adaptor is coupled with the vial. In some embodiments, the bag expands within the vial as liquid is removed from the vial via the adaptor, thereby regulating pressure within the vial. In other embodiments, a vial comprises a bag for regulating pressure within the vial as liquid is removed therefrom. In some embodiments, a vial adaptor is coupled with the vial in order to remove the liquid. In some embodiments, as the liquid is removed from the vial via the adaptor, the bag expands within the vial, and in other embodiments, the bag contracts within the vial.
US08882737B2	Container filled with a liquid concentrate for making dialysate A self standing bag having two side wall sheets and a bottom sheet. To flatten the bag, the bottom sheet is sandwiched between the two side wall sheets and symmetrically folded along a line parallel to its bottom edge, separating the bag into a four-layer part and a two-layer part. In the two-layer part, the bag includes first sloped sealing lines extending between a first two points on the top edges of the side wall sheets and spaced from the vertical side wall edges by a first distance, to a second two points spaced from the vertical edges of the side wall sheets by a second distance less than the first distance. The four-layer part includes second sloped sealing lines extending between the second two points and a third two points on the bottom edges of the side wall sheets.
US08882733B2	Diaper for treatment of diaper rash and methods of using such a diaper A diaper for treatment of diaper rash and methods of using such a diaper to treat diaper rash are provided. The diaper may include a first layer having inner and outer surfaces and including a front portion, a rear portion, and a middle portion extending between the front and rear portions and configured to be positioned between the legs of a user when worn. A liquid absorbent element may be coupled to the inner surface of the first layer and disposed proximate at least the front and middle portions. An opening may be defined in the rear portion of the first layer to expose at least a portion of the user's buttocks to open air when worn. An air and liquid permeable mesh layer may be permanently or removeably attached adjacent the opening and may cover at least part of the opening.
US08882732B2	Valve for ostomy pouch A valve that is sealable to an associated container having an interior fluid storage region is adapted to permit and stop flow of fluid from the fluid storage region. The valve includes a body sealable to the container and a stem mounted to the body having a portion in flow communication with the storage region. The stem is movable relative to the body between an open position to permit flow from the storage region through the valve, and a closed position to stop flow through the valve. The stem has a grasping region spaced from the body that is adapted rotate the stem to move the valve between the open and closed positions. The grasping region has first and second sides. One of the sides has a tactile indicator to provide indication of the position of the valve, the other side is devoid of the tactile indicator.
US08882727B2	Needle having a safety device A needle has a distal end, a proximal end, and a stem extending there between, as well as a tip at the distal end. The needle is provided with a safety device being arranged so as to be capable of sliding over the stem and a second position at the distal end of the stem. The safety device also includes a recess having a proximal opening and a distal opening for the needle stem to pass there through, the tip of the needle being inside the recess when the safety device is in the second position. The device includes a closing device that closes the distal opening of the recess when the needle tip is inside the recess.
US08882722B2	Medicament injection device with lockout feature A lockout feature for an injection device includes a time lock that prevents a user from administering a dose of medicament prior to a pre-determined time interval. The lockout feature can interface with a cap and dose setting module to prevent removal of the cap or it can work to disable the dose delivery module to prevent an injection from occurring.
US08882709B2	Injection arrangement The invention relates to a pump unit, replaceably attachable to a reusable backend of an injection arrangement for delivering a liquid medicament, the pump unit comprising a medicament inlet, a medicament outlet and a pump for delivering the liquid medicament from the inlet to the outlet, wherein a medicament container is arranged in the pump unit, wherein a fluid communication between the medicament container and the pump is establishable when the pump unit is attached to the reusable backend.
US08882708B2	Mating mechanism for a pressurizing unit and corresponding sleeve in a medical fluid injection device In general, this disclosure relates to techniques for providing a mating mechanism between at least one pressurizing unit and at least one corresponding sleeve in a powered medical fluid injection device. An example powered medical fluid injection device includes a sleeve and an injector head coupled to the sleeve. The sleeve has a notch with a predefined shape and size. The sleeve is configured to receive a pressurizing unit (such as a syringe) having an external tab with a predefined shape and size that are substantially identical to the predefined shape and size of the notch in the sleeve, such that the tab mates with the notch when the sleeve receives the pressurizing unit. The injector head is configured to inject a quantity of a medical fluid from the pressurizing unit during operation.
US08882705B2	Steerable catheter with in-plane deflection An improved steerable catheter with in-plane deflection comprises a catheter body having proximal and distal ends and a lumen extending therethrough and a tip section at the distal end of the catheter body. The tip section comprises a flexible plastic tubing having a pair of diametrically-opposed lumens extending therethrough. The catheter also provides two puller wires manipulated through a control handle at the proximal end of the catheter body. Each puller wire extends through one of the pair of lumens in the tip section and through the lumen of the catheter body and is anchored to the control handle at its proximal end and anchored to the tip section at its distal end. The deflection mechanism is configured to generally define a plane along which deflection most readily occurs and an edge along which deflection is most readily avoided. The deflection mechanism extends longitudinally along a centerline of the tip section between the first and second puller wire and is configured generally with a cross section having a thinner dimension and a thicker dimension to bias the tip section to deflect in a plane parallel with the thinner dimension of the deflection mechanism and to resist deflection in a plane perpendicular to thicker dimension.
US08882704B2	Injector An injector automatic limiting of the operating pressure of the injector as determined by the selection of a flow rate; a syringe cradle having a warming capability; a purge/retract trigger for control of the injection procedure having intuitive direction (i.e., forward for injecting, reverse for filing), non-contact control transmission through the housing of an injector for an improved seal integrity, a speed lock, and/or the ability to change the concentration and/or flow rate of media or other fluid during an injection procedure; a switch to determine when the drive ram is in a “home” position; a “soft” on/off power switch separate from the injector; and a structure to prevent rotation of the drive ram about its axis of symmetry. Additionally, the injector system includes software for the control of various components.
US08882702B2	Medical fluid injection system One implementation provides a method to provide injection procedure information in an injection system. In this implementation, the method includes displaying a plurality of different injection procedure options in a user interface of said system, wherein said plurality of different injection procedure options including a cardiac procedure option and a non-cardiac procedure option. The method further includes receiving a user selection of an injection procedure from said displayed plurality of difference injection procedure options, processing a default set of injection parameters based upon said selected injection procedure, and displaying said default set of injection parameters within the user interface of the system prior to an injection.
US08882701B2	Advanced step therapy delivery for an ambulatory infusion pump and system Embodiments relate to systems, methods and devices for delivering a drug or other therapy to a patient with an ambulatory infusion pump configured to provide a series of tolerance-building steps leading up to a plateau delivery rate. The plateau delivery rate is maintained until the prescribed amount of drug or therapy fluid is delivered to the patient. Embodiments of the invention include providing the patient or other user with a mechanism to decrease, or step down, the therapy delivery rate if a tolerance was not achieved at a lower rate, and providing notifications prior to a step up in a dosage delivery rate.
US08882692B2	Hemodialysis system with multiple cassette interference A hemodialysis system for operation with a blood source and a dialysate source, the system including: (i) a first machine portion including a blood pump; (ii) a blood cassette operatively connected to the blood pump such that the blood pump can pump blood through the blood cassette when the blood cassette is in fluid communication with the blood source; (iii) a dialyzer fluidly connected to the blood cassette; (iv) a second machine portion separate from the first machine portion, the second machine portion including a dialysate pump; and (v) a dialysate cassette separate from the blood cassette, the dialysate cassette operatively connected to the dialysate pump such that the dialysate pump can pump dialysate through the dialysate cassette when the dialysate cassette is in fluid communication with the dialysate source, the dialysate cassette being fluidly connected to the dialyzer.
US08882690B2	Orthotic device and method of manufacture An orthotic device having a thin, flexible material defining a plantar wall and lateral, medial and posterior sidewalls. A fastening mechanism releasably secures the lateral and medial sidewalls together. In some embodiments, the plantar wall defines a laterally extending distal trimline positioned distal of the first metatarsal head and proximal of the third, fourth and fifth metatarsal heads when the foot is secured within the orthotic device. In other embodiments, the device includes a heel post having a distal terminal edge with a medial portion extending into the arch proximal to the navicular bone and a lateral portion positioned proximal of the arch. In still other embodiments, an elongate strip of padding material projects inwardly below and proximate the medial malleosus and the lateral malleosus and is positioned to inhibit withdrawal of the calcaneous bone. A method of manufacturing an orthotic device is also disclosed.
US08882689B2	Knee brace Provided is a brace including upper and lower frame members and upper and lower cuff members. An upper adjuster is coupled to the upper frame member and upper cuff member and is configured to enable selective adjustment of the distance between the upper frame member and the upper cuff member. An upper connector is coupled to the upper frame member and the upper cuff member and is configured to enable selective engagement between the upper frame member and the upper cuff member. A lower adjuster is coupled to the lower frame member and the lower cuff member and is configured to enable selective adjustment of the distance between the lower frame member and the lower cuff member. A lower connector is coupled to the lower frame member and the lower cuff member and is configured to enable selective engagement between the lower frame member and the lower cuff member.
US08882688B1	Orthotic joint stabilizing assembly An orthotic joint stabilizing assembly includes an assembly hinge, a first support and a second support carried by and pivotal with respect to each other about the assembly hinge, a hinge spring carried by the first support and the second support and having spring coils along substantially an entire length of the hinge spring and a spring tensioner carried by the assembly hinge and engaging the hinge spring.
US08882678B2	Pleural drainage system and method of use A pleural drainage system having an inflatable membrane and a method of using the system are disclosed. The pleural drainage system includes a pleural drainage catheter system. The pleural drainage catheter system includes an inflatable membrane and a drainage catheter integrally coupled to the inflation membrane, the drainage catheter defining a drainage lumen through which fluid is drawn from the pleural cavity, and an inflation lumen coupled for flow of inflation fluid to and from an interior of the inflatable membrane. The pleural drainage system further includes a suction system coupled to the drainage catheter and a fluid collector coupled to receive fluid from the drainage catheter. The pleural drainage system further includes an inflation system connected to deliver inflation fluid to the interior of the inflatable membrane. The pleural drainage system may be used to monitor an associated airleak in the pleural cavity of a patient.
US08882672B2	Method and system for tissue imaging and analysis A method for detecting abnormal tissue in a region of healthy tissue, comprising:a) making a first measurement of ultrasound backscattered from the region; b) heating the region, at least after the first measurement; c) making one or more additional measurements of ultrasound backscattered from the region after some or all of the heating; and d) analyzing the measurements to detect the abnormal tissue by finding one or both of differences in changes in temperature and differences in thermal expansion, caused by the heating, between the abnormal tissue and the healthy tissue.
US08882671B2	Ultrasonic diagnostic device, ultrasonic image processing apparatus, ultrasonic image acquiring method and ultrasonic diagnosis display method Volume data are collected by swing scanning in which frames in different field angle settings are mixed by a wide scan set at a wide field angle to image a diagnostic target and an index part for recognizing the position of the diagnostic target and by a narrow scan set at a field angle θ2 narrower than the field angle in the wide scan to image the diagnostic target with high time resolution. Then, the wide ultrasonic image is used to set spatial coordinates based on the index part. The spatial coordinates are used to align the narrow ultrasonic image. While this positional relation is being maintained, the wide ultrasonic image, the narrow ultrasonic image and a given ultrasonic image are displayed in a predetermined form.
US08882665B2	Method and/or system for multicompartment analyte monitoring Subject matter disclosed herein relates to monitoring and/or controlling levels of an analyte in bodily fluid. In particular, estimation of a concentration of the analyte in a first physiological compartment based upon observations of a concentration of the analyte in a second physiological compartment may account for a latency in transporting the analyte between the first and second physiological compartments.
US08882663B1	Secure patient data recorder for recording monitored vital sign data A monitor and recorder system having a monitor unit for gathering vital sign data from a patient and a memory module for automatically recording the data. Means are provided for protecting the data from accidental or intentional deletion of the data or corruption or damage to the memory module without proper authorization. The data is recorded in a circular memory such that when data must be deleted, the last-recorded data is deleted first. A procedure is disclosed for preserving all data for at least a minimal period of time in case an event such as a patient death occurs.
US08882661B2	Retractor A retractor device for spearing the body tissue apart is provided. The retractor includes a housing configured to include a plurality of sections, wherein each section is configured to accommodate placement of at least one blade, a blade holding mechanism configured to secure the at least one blade within the housing, a translation mechanism configured to provide translation movement of at least one of the sections, and a rotation mechanism configured to provide rotation movement of at least one blade.
US08882657B2	Instrument having radio frequency identification systems and methods for use One RFID equipped instrument includes an elongate body with a plurality of uniquely identified radio frequency identification chips spaced along the length of the elongate body. One system used for determining the position of an instrument includes an instrument; a plurality of radio frequency identification chips attached to the instrument; a reader connected to an antenna and adapted to communicate with each radio frequency identification chip using the antenna. One method for determining the position of an instrument using radio frequency identification chips includes providing a radio frequency identification chip reader and antenna; providing an instrument having a longitudinal axis and comprising a plurality of radio frequency identification chips placed along the longitudinal axis; moving the instrument relative to the antenna; and using information about a radio frequency identification chip detected by the antenna to determine the position of the instrument.
US08882656B2	Diagnostic catheter using a vacuum for tissue positioning A diagnostic catheter and method of use for analyzing tissue is provided. A method for analyzing tissue in accordance with one embodiment of the present invention includes inserting a catheter having a sensor at its distal end into the body of a patient, applying suction through the catheter to secure the tissue to the catheter and then analyzing the tissue with the sensor. An apparatus for analyzing tissue within the body of a patient in accordance with an alternative embodiment of the present invention is also provided. This alternative embodiment includes a catheter having a first end and a second end, the first end having an orifice and a sensor, the catheter also having a lumen.
US08882650B2	EyeLid plaque An eyelid plaque and a method of using the plaque to treat eye cancers. The eyelid plaque is placed on the eyelid such that it defines an enclosure within which the radiation source resides. The enclosure defines a radiation shield that reduces radiation entering other organs and structures proximate the cancer being treated.
US08882648B2	Method and apparatus for assembling and folding absorbent articles Aspects of the methods herein relate to the fabrication of diaper pants wherein side panels connected with the first waist region of a discrete chassis are conveyed in a first direction until a second waist region advances past a nip. The crotch region of the chassis is then redirected into the nip, folding the chassis to position the second waist region into a facing relationship with the first waist region. The folded chassis is then conveyed in a second direction with the side panels positioned on panel conveyors extending laterally outward from the first waist region. As the folded chassis travels in the second direction, the panel conveyors twist to position end regions of the side panels to connect with the second waist region of the folded chassis. The side panels and the waist regions of the folded chassis may also be compressed between the panel conveyors and a roller.
US08882641B2	Exercise apparatus and method of using An exercise apparatus and method of use for a total body workout. The exercise apparatus includes at least one stationary exercise equipment directed for lower body exercise, and at least one resistance device for upper body exercise deployed over the at least one stationary exercise equipment. Also included is a system adapted for providing a total body workout for an indoor cycling class that includes a plurality of stationary indoor cycling bikes and a plurality of resistance bands, one set of resistance bands deployed over each of the plurality of stationary indoor cycling bikes. The system enables users of the plurality of stationary indoor cycling bikes and resistance devices to simultaneously exercise the upper and lower body.
US08882638B2	Exercise machine An exercise machine equipped with a device designed to be driven to move by the user during a workout, by applying a muscular force against a resistant load and which includes: a detector for detecting the muscular power applied by the user to the device; a display; a computer connected to the display and having access to a memory containing a plurality of values, representative of the power nominally absorbed by a plurality of corresponding electric household appliances, and digital data for graphically representing the plurality of electric household appliances, the computer being programmed for: comparing the power detected by the detector and at least one of the power values contained in the memory; and for generating on the display, depending on the comparison, a graphical output of the comparison, including a graphical representation of at least one of the electric household appliances, generated based on the digital data.
US08882630B2	Transmission A racing transmission. The racing transmission has a low gear, reverse gear, neutral and a direct drive gear. The transmission utilizes a drive shaft and two sets of planetary and sun gears. The transmission does not use a countershaft to accomplish low and reverse.
US08882627B2	Electric variable transmission for hybrid electric vehicles with four forward modes and six fixed gears The present disclosure provides a power split transmission with four Electric Variable Transmission (EVT) modes and six fixed gears for use in hybrid electrical vehicles (HEV). The present disclosure utilizes two electric motors (“E-motors”), an engine, three planetary gear sets, and five selectively engageable clutches. The clutches are engaged in different combinations to engage the different gears and EVT modes. In the six fixed gears, power is transmitted only on the mechanical path for the highest transmission efficiency. In the four EVT modes, a part of the power is transmitted electrically. The EVT modes are designed for the lowest power split ratios, allowing the use of low powered E-motors. Additionally, the present disclosure can include a front E-motor design allowing scalable E-motors and a modular transmission design, and a middle E-motor design.
US08882626B2	Continuously variable ratio transmission A multi-regime continuously variable ratio transmission has a transmission input shaft, a transmission output shaft, and a ratio varying unit having a rotating input and a rotating output, the rotational axes of the input and the output being coaxial. A shunt having first and second epicyclic gear sets is connected across the ratio varying unit. One gear set has an input driven by the input shaft and an input driven by one side of the ratio varying unit and the other gear set has an input from the first gear set and an input from one side of the ratio varying unit. The gear sets rotate about a common axis and are offset with respect to, and parallel to, the rotational axes of the input and output of the ratio varying unit. A clutch is operable to selectively connect the output of the second gear set to the output shaft.
US08882625B2	Transmission module for a lorry A lorry 1 comprises a combustion engine 3 which is connected via the transmission module 5 to the input shaft 7 of an automatic transmission 9 with switchable gear settings. The output shaft 11 of the transmission 9 is connected to the wheels 15 of the lorry via a differential 13. The transmission module 5 comprises a clutch 17 which has two clutch parts 17A and 17B that can be coupled to each other. The transmission module 5 further comprises a part module 19 which has an input 21 and an output 23. The part module 19 comprises a bypass transmission 25 with three rotational members 27, 29, 31 of which the third rotational member 31 can be coupled to the firm world 35 via a brake 33.

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