| Document | Document Title |
|---|---|
| US11066658B2 |
Long-acting coagulation factors and methods of producing same
Polypeptides comprising at least one carboxy-terminal peptide (CTP) of chorionic gonadotrophin attached to the carboxy terminus but not to the amino terminus of a coagulation factor and polynucleotides encoding the same are disclosed. Pharmaceutical compositions comprising the polypeptides and polynucleotides of the invention and methods of using and producing same are also disclosed. |
| US11066656B2 |
PH20 polypeptide variants, formulations and uses thereof
Modified PH20 hyaluronidase polypeptides, including modified polypeptides that exhibit increased stability and/or increased activity, are provided. Also provided are compositions and formulations and uses thereof. |
| US11066654B2 |
Methods and compositions for reducing serum lipids
In certain aspects, the present invention provides compositions and methods for modulating (promoting or inhibiting) growth of a tissue, such as bone, cartilage, muscle, fat, brown fat and/or neuronal tissue and for treating metabolic disorders such as diabetes and obesity, as well as disorders associated with any of the foregoing tissue. |
| US11066645B2 |
Isolation and cultivation of stem/progenitor cells from the amniotic membrane of umbilical cord and uses of cells differentiated therefrom
The present invention relates to a method of promoting skin rejuvenation in a subject. The method comprises administering to the subject an effective amount of a cellular extract of epithelial or mesenchymal stem/progenitor cells isolated from the amniotic membrane of the umbilical cord, wherein the cellular extract contains growth factors and peptides and is in the form of a supernatant into which the epithelial or mesenchymal stem/progenitor cells secrete the growth factors and peptides. |
| US11066644B2 |
Method of producing natural killer cells and composition for treating cancer
A method for producing natural killer cells is disclosed. The method comprises isolating peripheral blood mononuclear cells (PBMCs) from a blood sample; isolating at least one of CD56+ cells and/or CD3−/CD56+ cells from the PBMCs; and co-culturing the at least one of CD56+ cells and/or CD3−/CD56+ cells with a combination of feeder cells in the presence of a cytokine. A composition for treating cancer is also disclosed. The composition comprises the CD56+ natural killer cells produced by the disclosed method and a cytokine. |
| US11066642B2 |
Preparation of retinal pigment epithelium cells
A method of generating retinal pigment epithelium cells is disclosed. Cell populations comprising same and uses thereof are also disclosed. |
| US11066641B2 |
Method for inducing differentiation of corneal epithelial cells from pluripotent stem cells
The present invention relates to a method for inducing the differentiation of corneal epithelial cells from pluripotent stem cells. More specifically, the present invention relates to a method for autonomously differentiating pluripotent stem cells, such as human iPS cells, into ectodermal cell lineage in a serum-free medium without using feeder cells and inducing the differentiation of the resultant ocular surface ectodermal lineage cells into corneal epithelial cells. |
| US11066638B2 |
Method of preparing bacterial ghosts from gram-positive bacteria by hydrochloric acid treatment
The present invention relates to bacterial ghosts, and more particularly, to a method of preparing bacterial ghosts from gram-positive bacteria by hydrochloric acid treatment. Specifically, according to the present invention, when gram-positive bacteria were cultured after being treated with a minimum inhibitory concentration (MIC) of hydrochloric acid capable of inhibiting colony formation of gram-positive bacteria, bacterial ghosts were effectively formed. Since the formed bacterial ghosts have no intracellular proteins or DNA while preserving cell wall integrity, the risk of side effects such as secondary infection caused by bacterial growth when the bacterial ghosts are administered to humans is low. Therefore, the bacterial ghosts prepared from gram-positive bacteria according to the method of the present invention may be effectively used as a vaccine or a foreign antigen carrier for preventing or treating gram-positive bacterial infection. |
| US11066637B1 |
Particulate structure with a high concentration of live bacteria and method of preparing the same
A live bacteria-containing particulate is provided, wherein the particulate comprises a bacterial strain, a first covering layer, and a second covering layer, and wherein the first covering layer is in-between the cell membrane and cell wall of the bacterial strain and the bacterial strain is dispersed in the second covering layer. A method of preparing a live bacteria-containing particulates is also provided, wherein the method comprises the following steps: (a) subjecting a bacterial strain to a three-stage fermentation to obtain a fermentation broth; (b) concentrating the fermentation broth to provide a concentrated bacterial solution; (c) mixing the concentrated bacterial solution with a protective agent; and (d) drying the mixture to provide live bacteria-containing particulates. |
| US11066636B2 |
Microchip, microchip controlling apparatus and microchip controlling system technical field
A microchip includes a cell accepting section, a lysis solution chamber and a lysis reaction chamber. The cell accepting section accepts cells obtained from a subject. The lysis solution chamber stores lysis solution for lysis of the cells. The lysis reaction of the cells is executed in the lysis reaction chamber. |
| US11066634B2 |
Culture device and methods for enumerating mold colonies
A thin film culture device for enumerating mold colonies is provided. The device comprises water-resistant first and second substrates with a growth region disposed therebetween, a dry, cold water-soluble gelling agent disposed in the growth region, and an effective amount of a calcium-chelating compound disposed in the growth region. The effective amount of calcium-chelating compound is capable of reducing a rate of lateral enlargement of the colony-forming unit growing in the culture device relative to the rate of lateral enlargement of a colony of the same mold species growing in an otherwise identical culture device that does not contain the effective amount disposed in the growth region, wherein reducing the rate of lateral enlargement of the colony-forming unit does not substantially delay detection of the colony. A corresponding method is also provided. |
| US11066625B2 |
Blends containing enantiomerically pure Ambrocenide®
The present invention relates in particular to a mixture comprising the compound of formula (Ia) as described herein, wherein the mixture is free or essentially free of the compound of formula (Ib) as described herein, preferably of the compounds of formulae (Ib) and furthermore (Ic) and/or (Id) as described herein. The invention further relates to a method for manufacturing said mixture, fragrance substance compositions containing or consisting of said mixture, perfumed products containing said mixtures or fragrance substance compositions, and various methods and uses for imparting, modifying and/or enhancing certain odour notes. |
| US11066622B2 |
Synergistic lubricants with reduced electrical conductivity
A method of lubricating at least a portion of a powertrain in a vehicle with an electric motor with a functional fluid composition containing greater than 50 wt % of a base oil; and an additive composition prepared by mixing: a) a hydrocarbyl acid phosphate of the formula (I) to provide at least 50 ppmw phosphorus to the functional fluid composition; wherein R is a C1-C6 hydrocarbyl group and R1 is selected from hydrogen and a C1-C6 hydrocarbyl group; b) an amount of one or more calcium-containing detergent(s) sufficient to provide at least 25 ppmw calcium to the functional fluid composition; and c) one or more nitrogen containing dispersants in an amount sufficient to provide greater than 20 ppmw of nitrogen to the functional fluid composition, all based on the total weight of the functional fluid composition. Functional fluid compositions containing the above-mentioned components and lubricating methods are also disclosed herein. |
| US11066616B1 |
Process for making biofuel from spent coffee grounds
A system and process for producing biofuel from spent coffee grounds (SCGs) comprises the steps of performing a first operation comprising the steps of obtaining spent SCGs from a source, washing the SCGs, mixing the washed SCGs with an inorganic acid and heating and stirring the washed SCGs to form a SCG slurry without separating coffee oil, drying the SCG slurry, mixing the dried slurry with a solvent and heating the dried slurry and solvent mixture to create a reaction to produce biofuel and residual grounds, and separating the biofuel from the solvent and the residual grounds. The process further includes the step of using an activation agent and heating the residual grounds and the activation agent to create activated residual grounds. Biochar is also produced without activation and heating de-oiled SCGs at lower temperatures without oxygen. |
| US11066605B2 |
Systems and methods for catalytic upgrading of vacuum residue to distillate fractions and olefins
Systems and methods for upgrading a heavy oil feed to a light product comprising distillate fractions and olefins, the method including combining a heavy oil feed with a naphtha-based cracking additive to produce a mixed heavy oil feed; heating the mixed heavy oil feed with a nano-zeolite catalyst to effect catalytic upgrading of the mixed heavy oil feed to produce lighter distillate fractions and olefins in an upgraded product; and separating the lighter distillate fractions from the olefins. |
| US11066601B2 |
Composition for etching, method for etching insulator and method for manufacturing semiconductor device, and novel compounds
An etching composition contains phosphoric acid, phosphoric anhydride, a compound represented by the following Formula 1, and a silane compound comprising at least one silicon (Si) atom, excluding the compound represented by Formula 1: wherein, in Formula 1, A is an n-valent radical, where n is an integer of 1 to 6, L is a direct bond or hydrocarbylene, Y is selected from NR1, O, PR2 and S, where R1 to R2 are independently hydrogen, halogen, a substituted or unsubstituted hydrocarbyl group, or non-hydrocarbyl group, X and Z are independently selected from N, O, P and S, and Ra to Rc are independently an unshared electron pair, hydrogen, or a substituted or unsubstituted hydrocarbyl group. |
| US11066599B2 |
Production method for carbon-based light-emitting material
Provided is a production method for a carbon-based light-emitting material that generates light having a wavelength of 500 to 700 nm when exposed to excitation light having a wavelength of 300 to 600 nm. The production method comprises a step for mixing and heating a starting material containing ascorbic acid, an acid catalyst containing an inorganic acid, and a solvent. |
| US11066598B2 |
Dye-sensitized upconversion nanophosphor
Provided is a dye-sensitized upconversion nanophosphor including a core, a first shell surrounding at least part of the core, and an organic dye bonded to a surface of the nanophosphor which has an absorption band ranging from 650 nm to 850 nm and which is excited in a near-infrared region to emit visible light. The dye-sensitized upconversion nanophosphor may be included in a display apparatus, a fluorescent contrast agent, or an anti-counterfeiting code. The organic dye may be an IR-808 dye. |
| US11066594B2 |
Fluoropolymers to reduce retention of nanosurfactants to carbonate reservoir rock for applications in oil fields
Embodiments of the disclosure provide compositions and methods suitable for injection of a nanosurfactant composition into a hydrocarbon-bearing formation for enhanced recovery operations. The nanosurfactant composition includes nanoassemblies that contain a petroleum sulfonate surfactant, mineral oil, a zwitterionic co-surfactant. The nanosurfactant composition also includes a functionalized zwitterionic copolymer present in an aqueous environment. |
| US11066591B2 |
Effective pour point depressants for amidoamine emulsifiers
A composition comprising an oleaginous base fluid, an emulsifier and a liquid tertiary amide is disclosed. A wellbore fluid may include an oleaginous continuous phase, a non-oleaginous discontinuous phase and the composition to stabilize the non-oleaginous discontinuous phase within the oleaginous continuous phase. A method comprising adding the composition to a wellbore fluid and emplacing the wellbore fluid mixed with the composition into a wellbore is also provided. |
| US11066588B2 |
Deicing composition comprising lignocellulosic byproducts
Provided is a solvent borne deicing composition which includes in a solvent, a blend of an inorganic salt, a low molecular weight lignin in an amount of at least 5 weight % (or 10 or 15 or 20 weight %) to 30 or 40 or 50 weight % of the solids, and hemicellulose in an amount of at least 0.1 weight % (or 0.2 or 0.5 or 1.0 or 2.0 or 5.0 weight %) to 20 weight % (or 10 or 15 or 18 or 25 or 30 weight %) of the solids. |
| US11066587B2 |
Sealant material
Use of a sealing material which is a multifilament or spun yarn coated with a joint sealing composition to seal a joint in a pipe system in which system a fluid having corrosion inhibitors such as diammonium dimolybdate or benzotriazole; and/or sludge removers; and/or an alcohol such as propane diol, or ethylene glycol; and/or a hydrocarbon such as diesel, including biodiesel, fuel oil, or hydraulic oil; and/or steam at a temperature of at least 180° C. and a pressure of at least 10 bar (1000 kPa); is to be passed through the sealed joint. It is surprising that the sealing materials of the invention can maintain a sealed joint despite exposure to such materials. |
| US11066581B2 |
Pressure-sensitive adhesive composition for foldable display
Provided is a pressure-sensitive adhesive composition for a foldable display, more particularly, a pressure-sensitive adhesive composition for a foldable display which, by satisfying a specific range of storage modulus for each frequency at a temperature of 50° C. or more as well as at low temperature and room temperature, not only allows excellent folding properties to be realized but also satisfies excellent adhesion, excellent heat resistance, and excellent recovery rate requirements at the same time. |
| US11066580B2 |
Pressure-sensitive adhesive composition for foldable display
Provided is a pressure-sensitive adhesive composition for a foldable display, more particularly, a pressure-sensitive adhesive composition for a foldable display which, by satisfying a specific range of storage modulus at high temperature as well as at low temperature and room temperature, not only allows excellent folding properties to be realized but also satisfies excellent adhesion, excellent heat resistance, and excellent recovery rate requirements at the same time. |
| US11066577B2 |
Electrically conductive adhesive film and dicing-die bonding film using the same
The electrically conductive adhesive film comprises a metal particle (P) and a resin (M), the resin (M) comprises a thermosetting resin (M1), and the metal particle (P) has an average particle size (d50) of 20 μm or less and comprises 10% by mass or more of a first metal particle (P1) having a fractal dimension of 1.1 or more when viewed in a projection drawing in a primary particle state. |
| US11066576B2 |
Drywall joint tape with dual purpose adhesive backing
A joint tape to be applied to wallboard is provided and includes a base substrate having opposing sides. In certain embodiments, a first adhesive layer is applied to one of the sides of the base substrate and a second adhesive layer is applied to the first adhesive layer, where the first adhesive layer is different than the second adhesive layer. In certain other embodiments, two different adhesives are used in a single adhesive layer. In use, the joint tape is positioned over and removably secured to a joint or corner between adjacent wallboard panels using the first adhesive layer. After the joint tape is in position, joint compound is applied to the joint tape, and the water in the joint tape activates it to form a secure bond with the wallboard panels. |
| US11066575B2 |
Chemical mechanical planarization for tungsten-containing substrates
Chemical mechanical polishing (CMP) compositions, systems and methods of using the compositions for polishing tungsten or tungsten-containing substrates. The compositions comprise nano-sized abrasive; metal compound coated organic polymer particles as solid state catalyst; oxidizer; tungsten corrosion inhibitor; and a water based liquid carrier. |
| US11066572B2 |
Method of preparing high-performance water-soluble acrylic resin with high solid content and low viscosity
A preparation method and uses of a high-performance water-soluble acrylic resin with high solid content and low viscosity. The method polymerizes the free radical solution in a mixed solvent by a continuous method to produce an acrylic resin and the resin is rendered water-soluble through salification. Modification with versatate introduces a large branched structure. Silicone functional monomer is used to modify the acrylic resin. Amino resin is used as a curing agent to directly prepare a waterborne amino-acrylic coating with a simple process, and the coating has good hardness, fullness, water and alcohol resistance and salt spray resistance. |
| US11066568B2 |
Dispersant, dispersion and ink composition, and preparing method thereof
A dispersant, a dispersion and an ink composition including the dispersant, and a method of preparing the dispersion and the ink composition, in which the dispersant includes: (A) 0.5 to 30% by weight of a compound selected from at least one of acetylene glycol represented by the specific formula (1) and an ethoxylated substance of acetylene glycol represented by the specific formula (2); (B) 5 to 98% by weight of a nonionic aryl phenol compound represented by the specific formula (3); and (C) 1 to 70% by weight of an anionic aryl phenol compound represented by the specific formula (4), and wherein the total amount of components (A) to (C) is 100% by weight. |
| US11066564B2 |
Aqueous pigment dispersion
The present invention relates to a water-based pigment dispersion containing a polymer dispersant and a pigment, the polymer dispersant being prepared by crosslinking a carboxy group-containing water-insoluble polymer (A) with a water-insoluble polyfunctional epoxy compound, in which carboxy groups of the water-insoluble polymer (A) are at least partially neutralized by an alkali metal compound, and the water-based pigment dispersion satisfies the following conditions 1 to 3. The water-based pigment dispersion of the present invention can exhibit excellent redispersibility capable of suppressing solidification of the pigment or the polymer in ink ejection nozzles and can ensure good storage stability under high-temperature conditions. The conditions 1 to 3 are as follows: Condition 1: a value calculated according to the formula: {[100−(neutralization degree)−(crosslinking degree)]/100}×[acid value of water-insoluble polymer (A)] is from −30 to 30 mgKOH/g: Condition 2: a value calculated according to the formula: [(neutralization degree)/100]×[acid value of water-insoluble polymer (A)] is from 80 to 180 mgKOH/g; and Condition 3: a value calculated according to the formula: [(crosslinking degree)/100]×[acid value of water-insoluble polymer (A)] is from 80 to 180 mgKOH/g. |
| US11066562B2 |
Acrylamide-containing photo active co-solvents
The present disclosure is drawn to an acrylamide-containing photo active co-solvent, including a bis-tris propane co-solvent or a polypropylene oxide amine co-solvent modified with an acryloyl group to form the acrylamide-containing photo active co-solvent. |
| US11066559B2 |
Laundry detergent composition comprising a particle having hueing agent and clay
The present invention relates to a laundry detergent composition comprising a particle comprising hueing agent and clay. The particle can be incorporated into laundry detergent products, such as a laundry detergent powder. The particle exhibits an excellent storage stability profile with very little bleeding of the hueing dye from the particle, exhibits excellent fabric deposition of the hueing dye during a laundering process without causing any spot staining of the fabric, and does not impact the visual appearance of a laundry detergent powder when incorporated therein. |
| US11066556B2 |
Polycarbonate resin composition
Provided is a polycarbonate-based resin composition containing: a polycarbonate-polyorganosiloxane copolymer (A-1) which contains a specific repeating unit and in which a polyorganosiloxane block has an average chain length of 20 or more and less than 60; a polycarbonate-polyorganosiloxane copolymer (A-2) which contains a specific repeating unit and in which a polyorganosiloxane block has an average chain length of 60 or more and less than 500; and a polycarbonate-based resin (A-3) except the polycarbonate-polyorganosiloxane copolymer (A-1) and the polycarbonate-polyorganosiloxane copolymer (A-2), wherein the ratio of the polycarbonate-based resin (A-3) to the total weight of the polycarbonate-polyorganosiloxane copolymer (A-1), the polycarbonate-polyorganosiloxane copolymer (A-2), and the polycarbonate-based resin (A-3) is 10 mass % or more. |
| US11066553B2 |
Imidazoyl urea polymers and their use in metal or metal alloy plating bath compositions
The present invention relates to imidazoyl urea polymers and their use in aqueous acidic plating baths for metal or metal alloy deposition such as electrolytic deposition of copper or alloys thereof in the manufacture of printed circuit boards, IC substrates, semiconducting and glass devices for electronic applications. The plating bath according to the present invention comprises at least one source of metal ions and an imidazoyl urea polymer. The plating bath is particularly useful for filling recessed structures and build-up of pillar bump structures. |
| US11066551B2 |
Oriented polylactic acid polymer based film
In one embodiment, a film is described comprising a mixture of semicrystalline polylactic acid polymer; polyvinyl acetate polymer having a glass transition temperature (Tg) midpoint as measured by differential scanning calorimetry of at least 25° C.; and plasticizer; wherein the film is oriented. In another embodiment, a film is described comprising a mixture comprising semicrystalline polylactic acid polymer, polymer having a midpoint Tg as measured by differential scanning calorimetry of at least 25° C., and plasticizer; wherein the mixture exhibits a single midpoint Tg and the single midpoint Tg ranges from 40° C. to 65° C.; and wherein the film is oriented and the oriented film exhibits a higher midpoint Tg ranging from 40° C. to 65° C. and a lower midpoint Tg ranging from 5 to 25° C. |
| US11066548B2 |
Polyphenylene ether resin composition, prepreg, metal-clad laminate, and printed wiring board
A polyphenylene ether resin composition includes a modified polyphenylene ether copolymer, a high-molecular-weight compound, and a crosslinking agent for the modified polyphenylene ether copolymer. The modified polyphenylene ether copolymer includes a substituent having a carbon-carbon unsaturated double bond at a molecular chain end of the modified polyphenylene ether copolymer. The high-molecular-weight compound has a glass transition temperature (Tg) measured by differential scanning calorimetry of 20° C. or lower and has a number-average molecular weight Mn ranging from 1000 to 10000, inclusive. The crosslinking agent includes at least two carbon-carbon unsaturated double bonds per molecule, and includes at least one of dicyclopentadiene acrylate and dicyclopentadiene methacrylate. In a cured state of the polyphenylene ether resin composition, the modified polyphenylene ether copolymer is phase separated from the high-molecular-weight compound. |
| US11066547B2 |
Thermoplastic resin composition, and molded article produced therefrom
A thermoplastic resin composition of the present invention comprises: a thermal stabilizer including a rubber-modified vinyl-based graft copolymer and a phenol-based thermoplastic resin thermal stabilizer including an aromatic vinyl-based copolymer resin and a phosphorus-based thermal stabilizer; and a zinc oxide which has an average particle size of approximately 0.5 to approximately 3 μm and a specific surface area BET of approximately 1 to approximately 10 m2/g. The thermoplastic resin composition has excellent low-odor and antibacterial properties. |
| US11066545B2 |
Lubricious structures, methods of making them, and methods of use
Embodiments of the present disclosure provide for lubricious structures (also referred to simply as “structure”), methods of making lubricious structures, methods of using lubricious structures, and the like. |
| US11066544B2 |
Optical resin composition and molded article
An optical resin composition includes a thermoplastic resin and a cross-linked structure-containing polymer. A photoelastic constant of the cross-linked structure-containing polymer and a photoelastic constant of the thermoplastic resin are opposite in sign, and a molded article with a thickness of 2 mm formed from the optical resin composition has a haze of 6% or less. |
| US11066543B2 |
Dispersant attached polytetrafluoroethylene particle, composition, layered material, electrophotographic photoreceptor, process cartridge, and image forming apparatus
A dispersant attached polytetrafluoroethylene particle on whose surface a dispersant having a fluorine atom is attached has a content of perfluorooctanoic acid of from 0 ppb to 25 ppb with respect to the polytetrafluoroethylene particle, and a composition contains a polytetrafluoroethylene particle and a dispersant having a fluorine atom in which a content of perfluorooctanoic acid is from 0 ppb to 25 ppb with respect to the polytetrafluoroethylene particle. |
| US11066542B2 |
Method of preparing thermoplastic resin, thermoplastic resin composition including the same, and method of manufacturing injection-molded article using thermoplastic resin composition
The present invention relates to a method of preparing a thermoplastic resin, a method of preparing a thermoplastic resin composition including the same, and a method of manufacturing an injection-molded article using the thermoplastic resin composition. By using a mixture of molecular weight modifiers having different reactivities according to the present invention, coagulation may be performed using a small amount of coagulant, productivity may be increased, and a molded article, which is manufactured using a thermoplastic resin, having excellent appearance characteristics along with superior mechanical strength, processability, or the like may be provided. |
| US11066540B2 |
Rubber crawler
Provided is a rubber crawler including a guide rubber that is reduced in heat generation and excellent in abrasion resistance and an inner peripheral rubber that is excellent in scratch resistance and abrasion resistance and having excellent adhesiveness between the guide rubber and the inner peripheral rubber.The rubber crawler of the present invention includes a guide rubber obtained by crosslinking a guide rubber composition and an inner peripheral rubber obtained by crosslinking an inner peripheral rubber composition, the guide rubber composition containing a rubber component (A) and a carbon black (B), the rubber component (A) containing a butadiene rubber and at least one selected from a natural rubber and isoprene rubber, and containing 50 to 80% by mass of the natural rubber and the isoprene rubber and 20 to 50% by mass of the butadiene rubber, the carbon black (B) containing a carbon black (B-1) having an N2SA of 60 to 125 m2/g and a DBP absorption of less than 130 mL/100 g and a carbon black (B-2) having an N2SA of less than 60 m2/g and a DBP absorption of 110 mL/100 g or more, and a total content of the carbon black (B-1) and the carbon black (B-2) is 25 to 65 parts by mass based on 100 parts by mass of the rubber component; the inner peripheral rubber composition containing a rubber component (a) and a carbon black (b), the rubber component (a) containing 60 to 100% by mass of SBR and 0 to 40% by mass of a diene-based rubber other than the styrene-butadiene rubber, and a carbon black in an amount of 50 to 70 parts by mass based on 100 parts by mass of the rubber component. |
| US11066533B2 |
Low smoke halogen free flame retardant thermoplastic elastomer compositions
Halogen-free flame retardant compositions comprising thermoplastic elastomers, which exhibit flame retardance and low-smoke emission. The flame retardant compositions comprise (a) one or more thermoplastic elastomers; and (b) a flame retardant mixture comprising: magnesium hydroxide, aluminium trihydrate, melamine cyanurate, and optionally a phosphate ester flame retardant. |
| US11066532B2 |
Process for the production of expanded material based on sulfone polymers
A process for the production of expanded material based on sulfone polymers includes an extrusion step in an extruder of virgin sulfone polymer with the injection of at least one expanding agent and in the presence of at least one nucleating agent, and a recycling step of part of the expanded material, which provides a recycled product used as raw material fed to the extruder in combination with the virgin sulfone polymer. |
| US11066531B2 |
Surface treatment liquid and hydrophilic treatment method
An object is to provide a surface treatment liquid which can firmly bond, while coating the surface of a treatment target with an extremely thin film, a coating whose hydrophilicity is unlikely to be lowered even when the coating is brought into contact with fats and the like to the surface of the treatment target and a surface treatment method using the surface treatment liquid described above. In a surface treatment liquid containing a resin (A) and a solvent (S), as the resin (A), a resin is used which includes a constituent unit (a1) that includes an organic group including a quaternary ammonium cation group and having a sulfonic acid anion group at a terminal and that is derived from an N-substituted (meth) acrylamide, and includes a reactive silyl group in at least one of molecular chain terminals, the concentration of the resin (A) in the surface treatment liquid is less than 2 mass % and the pH of the surface treatment liquid is 4 or less. |
| US11066525B2 |
Method and apparatus for separating lignocellulose particle fraction and lignin particle fraction, lignin particle composition, lignocellulose particle composition and their use
A method and an apparatus for separating lignocellulose particle fraction (3) and lignin particle fraction (4), in which crude lignin (1) formed from starting material (6) comprises lignocellulose particles and lignin particles. The method comprises adding stabilizing chemical (11) and/or hydrophobic chemical (12) into the crude lignin (1) in at least one step, and treating the crude lignin by separating the lignin particle fraction (4) and lignocellulose particle fraction (3) from each other in at least one separation step (2,8,9,10). Further, a lignocellulose particle fraction and a lignin particle fraction and their uses. |
| US11066524B2 |
Process for producing alkoxylated polyphenols
The invention relates to a process for producing at least one alkoxylated polyphenol comprising the following successive steps: (a) reacting at least one polyphenol, at least one alkoxylating agent, at least one catalyst, in the presence of at least one alkoxylated polyphenol as a solvent, the polyphenol/polyphenol alkoxylated weight ratio as a solvent being less than 2, preferably less than or equal to 1.5, more preferably less than or equal to 1, even more preferably less than or equal to 0.5; and (b) removing the residual alkoxylating agent. |
| US11066522B2 |
Amphiphilic polymer, amphiphilic polymer manufacturing method, contact lens material including the amphiphilic polymer, and contact lens manufacturing method
An amphiphilic polymer, an amphiphilic polymer manufacturing method, a contact lens material including the amphiphilic polymer, and contact lens manufacturing method are provided. The amphiphilic polymer includes poly(dimethylsiloxane) and amphiphilic chitosan bonded to the same. The contact lens material includes the amphiphilic polymer. The amphiphilic polymer manufacturing method includes providing a poly(dimethylsiloxane), providing an amphiphilic chitosan, and bonding the amphiphilic chitosan to the poly(dimethylsiloxane). |
| US11066521B2 |
Silicone elastomer composition
The present invention provides a tin-free, room temperature curable silicone elastomer composition, wherein the uncured composition is a putty. |
| US11066520B2 |
Vinyl-modified maleimide, composition and article made thereby
The present invention discloses vinyl-modified maleimide, a resin composition using the same and a preparation thereof. The vinyl-modified maleimide has better solvent selectivity and solvent compatibility. The obtained preparation can satisfy the properties of no crack between multilayer boards and high frequency and low dielectric properties maintained after moisture absorption. |
| US11066517B2 |
Processes for producing fluorinated ether compounds
Processes for producing a fluorinated ether compound are provided by which fluorinated ether compound capable of imparting excellent water/oil repellency, to a substrate surface or a hard coat layer can be easily produced in high yield. A process comprising reacting Rf(CF2)a—CF2OC(═O)Rf4 or Rf(CF2)a—C(═O)X1 with HN(—R1CH═CH2)2 to obtain Rf(CF2)a—C(═O)N(—R1CH2═CH2)2 and a process comprising obtaining the above product and reacting the product with HSiR2nL3-n to obtain Rf(CF2)a—C(═O)N(—R1CH2CH2SiR2nL3-n)2 wherein Rf is a linear polyfluoroalkyl group having at least two carbon atoms and at least one etheric oxygen atom between carbon atoms, Rf4 is a C1-30 perfluoroalkyl group or the like, X1 is a halogen atom, R1 is an alkylene group, a is an integer of from 1 to 5, R2 is a monovalent hydrocarbon group, L is a hydrolyzable group, and n is an integer of from 0 to 2. |
| US11066516B2 |
Polycarbonate resin composition and optical molded article using the same
The present invention relates to a polycarbonate resin composition for a light guide plate and an optical molded article using the same. The polycarbonate resin composition according to the present invention is excellent in transmittance and color tone uniformity required as the light guide plate, and also is excellent in processability and thus can be usefully used as a material of the light guide plate. |
| US11066502B2 |
Maleate-based copolymers and methods for preparing the same
The invention relates to copolymers of vinyl lactams with derivatized maleates. In particular, it relates to copolymers that are suitably used in the area of personal care and pharmaceuticals, to compositions comprising the copolymers and to methods for preparing the copolymers. |
| US11066501B2 |
Method for manufacturing an aqueous latex comprising particles of a fluoropolymer
The present invention pertains to a method for manufacturing a melt-processible fluoropolymer, to the melt-processible fluoropolymer obtainable by the process and to uses of the melt-processible fluoropolymer in various applications. |
| US11066500B2 |
Crosslinkable surfactants
A crosslinkable surfactant useful for preparing an emulsion polymerization composition; the crosslinkable surfactant including (a) a crosslinkable functionality and a hydrophobic tail with a Tung oil derivative structure, and (b) a polyalkylene oxide or polyglycerin part as hydrophilic head; an emulsion polymerization process using the crosslinkable surfactant; an emulsion polymerization composition; and a process for preparing the emulsion polymerization composition. |
| US11066493B2 |
Catalyst injection system for an olefin polymerization reactor
This disclosure relates to a method and an apparatus for the delivery of a multi-component olefin polymerization catalyst to a polymerization reactor. The components soluble in a first solvent are delivered under pressure along with that solvent in a first delivery conduit. The components that are insoluble in the first solvent but are soluble in a second solvent are delivered under pressure in a second delivery conduit which is arranged coaxially with and disposed within the first conduit, such that the inner conduit and outer conduit terminate at a common catalyst component mixing conduit which extends into the polymerization reactor and in which the catalyst components mix to form an active polymerization catalyst. |
| US11066487B2 |
Modified conjugated diene-based polymer and method of preparing the same
The present invention relates to a modified conjugated diene-based polymer, and more particularly, provides a modified conjugated diene-based polymer including a repeating unit derived from a conjugated diene-based monomer and a functional group derived from a modifier containing a compound represented by Formula 1 at one terminal, and a method of preparing the same. |
| US11066486B2 |
Polymers functionalized with imine compounds containing a cyano group
A method for preparing a functionalized polymer, the method comprising the steps of (i) polymerizing monomer to form a reactive polymer, and (ii) reacting the reactive polymer with an imine compound containing a cyano group. |
| US11066482B2 |
Specific plasmin inactivation by anticatalytic antibody
Methods and pharmaceutical compositions for treating hemorrhage or bleeding are provided. The pharmaceutical compositions include an effective amount of an antifibrinolytic composition that reduces or inhibits hemorrhage or bleeding in a subject. |
| US11066478B2 |
Intravesical therapy for bladder cancer
This invention relates to an intravesical therapy for bladder cancer. |
| US11066475B2 |
Chimeric antigen receptors specific for B-cell maturation antigen and encoding polynucleotides
Provided herein are chimeric receptors, such as chimeric antigen receptors (CARs), comprising BCMA-binding molecules, such as anti-BCMA antibodies and antigen-binding fragments thereof, such as heavy chain variable (VH) regions and single-chain antibody fragments, and encoding polynucleotides. In some embodiments, the anti-BCMA chimeric receptors specifically bind to BCMA. Among the anti-BCMA-binding molecules are human antibodies, including those that compete for binding to BCMA with reference antibodies, such as a non-human reference antibody. Also provided are genetically engineered cells expressing the CARs and uses thereof such as in adoptive cell therapy. |
| US11066473B2 |
Galectin-10 antibodies
The present invention relates to antagonists, particularly antibodies and antigen binding fragments thereof, that bind to the protein galectin-10, particularly human galectin-10. The galectin-10 antagonists disrupt the crystallization of galectin-10 and are therefore useful in methods of preventing and treating diseases and conditions wherein the pathology is linked to the formation/presence of Charcot-Leyden crystals (CLCs). |
| US11066468B2 |
Immunoconjugates with an intracellularly-cleavable linkage
The invention relates to therapeutic conjugates with improved ability to target various cancer cells containing a targeting moiety and a therapeutic moiety. The targeting and therapeutic moieties are linked via an acid cleavable linkage that increases therapeutic efficacy of the immunoconjugate. |
| US11066465B2 |
Antibodies and conjugates thereof
Provided herein are anti-VEGF-A antibodies and antibody conjugates thereof. Some embodiments of the antibodies can be conjugated to a moiety, such as a HEMA-PC polymer. Some embodiments of the antibody conjugates can retain or enhance antibody activity. The antibody and conjugate thereof can be particularly useful for treating diabetic retinopathy. Further provided are methods for conjugation of a polymer to a protein such as an antibody, such as IgG1. |
| US11066462B2 |
Method for the treatment of idiopathic pulmonary fibrosis
The invention is in the field of methods and preparations for medical treatments, in particular the treatment of idiopathic pulmonary fibrosis (IPF). The invention provides such methods wherein antibodies or fragments thereof that react with selected citrullinated epitopes are used in the treatment of IPF. Antibodies against citrullinated epitopes situated at the amino terminus of histone polypeptides H2A and H4 were found to be particularly useful. The invention therefore relates to an antibody specifically reactive with a citrullinated epitope on the N-terminus of deiminated histone H2A or H4 for use in the prevention or treatment of idiopathic pulmonary fibrosis. |
| US11066459B2 |
Hybrid immunoglobulin containing non-peptidyl linkage
The present invention provides a compound having the structure: A-B - - - Z wherein A is a biologically active structure of the compound; wherein Z is a protein component of the compound, which protein component comprises one or more polypeptides, wherein at least one of the one or more polypeptides comprises consecutive amino acids which (i) are identical to a stretch of consecutive amino acids present in a chain of an Fc domain of an antibody; (ii) bind to an Fc receptor; and (iii) have at their N-terminus a sequence selected from the group consisting of a cysteine or selenocysteine; wherein the dashed line between B and Z represents a peptidyl linkage; and wherein the solid line between A and B represents a nonpeptidyl linkage, as well as intermediates dimers thereof, and processes of producing the compounds of the invention. |
| US11066458B2 |
VEGF antagonist formulations suitable for intravitreal administration
Ophthalmic formulations of a vascular endothelial growth factor (VEGF)-specific fusion protein antagonist are provided suitable for intravitreal administration to the eye. The ophthalmic formulations include a stable liquid formulation and a lyophilizable formulation. Preferably, the protein antagonist has an amino acid sequence of SEQ ID NO:4. |
| US11066447B2 |
Aureobasidium derivatives and methods of synthesis
In general, the invention relates to AbA derivatives that are useful for treating infection. These novel compounds are shown to be effective in treating various fungal infections. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various fungal infections. |
| US11066445B2 |
Immunomodulators acting as antagonists of PD-1
The present disclosure provides novel macrocyclic peptides which inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases. |
| US11066443B2 |
Anti-bacterial peptide macrocycles and use thereof
The present invention relates to compounds of formula (I) wherein X1 to X8 and R1 to R8 are as described herein, as well as pharmaceutically acceptable salts thereof for the use in the treatment or prevention of infections and resulting diseases caused by Pseudomonas aeruginosa. |
| US11066442B2 |
Deuterated compounds, compositions, and methods for treating cancers associated with ETBR activation
Disclosed herein are deuterated compounds, pharmaceutical compositions thereof, and methods for treating ETBR-related cancers. Also disclosed herein is a delivery system for the controlled, systemic release of at least one deuterated ETBR antagonist, optionally in conjunction with an additional anti-oncologic agent. |
| US11066440B2 |
Processes for increasing plant protein yield from biomass
A process for increasing protein yield from biomass (beans, oilseeds, cereals, nuts, rice, soybeans, bran, etc.), as well as, for reducing the amount of chemical and biological reagents used in the process, involves application of multiple hydrodynamic cavitation treatments of a biomass suspension or other combination of biomass with solvents and reagents—in the preparation, extraction, and processing or the biomass and proteins. The biomass suspension is preferably subjected to at least three cavitation treatments in order to facilitate the crushing of biomass, splitting of fibers, and rupture of cell membranes, thereby increasing the mass transfer surface area and intensifying the extraction of protein and lipids. At the stage of washing and neutralization the protein solution may be subjected to a fourth cavitation treatment to obtain the purified protein. |
| US11066437B2 |
Methods and intermediates for the preparation of bile acid derivatives
The present disclosure relates to methods and novel intermediates useful in the preparation of a compound of formula I or pharmaceutically acceptable salt, hydrate, solvate or amino acid, sulfate or glucuronide conjugate, or prodrug thereof, comprising the step of reacting a compound of formula I-4 with a halogenating reagent to provide a compound of formula I-5a |
| US11066436B2 |
5′-phosphorothiolate mRNA 5′-end (cap) analogs, mRNA comprising the same, method of obtaining and uses thereof
The present invention relates to nucleotides, analogs of mRNA 5′-end (cap) containing sulfur atom at the position 5′ of 7-methylguanosine nucleoside. The disclosed compounds are recognized (bound and non-hydrolyzed) by DcpS enzyme (Decapping Scavenger), and thus may find therapeutic use as inhibitors thereof. DcpS is cap-specific enzyme with pyrophosphatase activity, which was identified as a therapeutic target in the treatment of spinal muscular atrophy (SMA). Some of the compounds disclosed have additional modifications in the phosphate chain, which modulate their affinity for DcpS enzyme. The present invention also relates to mRNAs modified at the 5′ end with mRNA 5′-end (cap) analogs containing 5′-phosphorothiolate moiety, which mRNAs have an increased stability and translational activity in cellular conditions, to a method of their preparation, their uses, and to a pharmaceutical formulation containing them, wherein L1 and L2 are independently selected from the group comprising O and S, wherein at least one of L1 and L2 is not O. |
| US11066434B2 |
Metal complexes comprising aniline type ligands
This invention relates generally to olefin metathesis catalysts comprising aniline type ligands, to the preparation of such catalysts, compositions comprising such catalysts, methods of using such catalysts, and the use of such catalysts in the metathesis of olefins. The invention has utility in the fields of catalysis, organic synthesis, polymer chemistry, and in industrial applications such as oil and gas, fine chemicals and pharmaceuticals. |
| US11066426B2 |
Methods of making porous molecular structures
Disclosed herein is a method of making a porous molecular structure from a solution comprising an insoluble metal containing material and a ligand-providing material. In some embodiments, the porous molecular structure can be a Metal-Organic Framework (MOF). Ionic metal salts are the most common type of metal source for MOF production, but dissolution of metal salts complicates solvent recycling and creates corrosion and oxidation issues through evolved nitrate and chloride anions. Elucidating information that leads toward more efficient production of these versatile nanomaterials, while extending the knowledge base of how MOFs form during reaction, is critical to advancing MOF materials into large-scale use. Disclosed herein are improved methods for controlled synthesis of porous molecular structures such as MOFs comprising a solution-based synthesis with insoluble metallic precursor. |
| US11066425B1 |
Oxo-substituted compound
Provided is a novel compound that has an excellent β-lactamase inhibitory effect. More specifically, provided is a compound represented by formula (1a), (1b) or (11) having an excellent β-lactamase inhibitory effect or a pharmaceutically acceptable salt thereof. By using this compound either in combination with a β-lactam drug or alone, a useful preventive or therapeutic agent for bacterial infections is provided. Also provided are useful preventive or therapeutic agents for treating various diseases with the combined use of the aforesaid compound and β-lactam drugs. |
| US11066422B2 |
Method of producing cycloalkyl(trifluoromethyl)benzene
An industrially excellent production method for cycloalkyl(trifluoromethyl)benzene is free of complicated steps, small in the number of steps, and high in production efficiency. Cycloalkyl(trifluoromethyl)benzene is produced by reacting a halogen-substituted trifluoromethyl benzene with magnesium metal to produce a Grignard reagent and cross-coupling the Grignard reagent with a cycloalkyl halide in the presence of an iron salt or a cobalt salt at a reaction temperature of 60° C. to 80° C. |
| US11066419B2 |
1H-pyrrole-2,5-dione compounds and methods of using same
The present invention relates to 1H-pyrrole-2,5-dione compounds and methods of using them to induce self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into tissue cells. |
| US11066418B2 |
Compound and thin film transistor and electronic device
Disclosed are a compound represented by Chemical Formula 1A or 1B, an organic thin film, a thin film transistor, and an electronic device. In Chemical Formulae 1A and 1B, X1, Ar1, R1 to R4, and n1 are the same as described in the detailed description. |
| US11066416B2 |
Rapafucin derivative compounds and methods of use thereof
The present disclosure provides macrocyclic compounds inspired by the immunophilin ligand family of natural products FK506 and rapamycin. The generation of a Rapafucin library of macrocyles that contain FK506 and rapamycin binding domains should have great potential as new leads for developing drugs to be used for treating diseases. |
| US11066414B2 |
Cot modulators and methods of use thereof
The present disclosure relates generally to modulators of Cot (cancer Osaka thyroid) and methods of use and manufacture thereof. |
| US11066409B2 |
Bicyclic nitrogen-containing heterocyclic derivatives and pharmaceutical composition comprising the same
Provided are a novel compound having an antagonistic activity for the P2X7 receptor, and a pharmaceutical composition having an antagonistic activity for the P2X7 receptor. The compound represented by Formula (I): wherein the symbols are defined in the specification, or a pharmaceutically acceptable salt thereof. |
| US11066408B2 |
Crystalline binary sodium salts of 5-methyl-(6S)-tetrahydrofolic acid with organic bases
The present invention is directed to crystalline salt of 5-methyl-(6S)-tetrahydrofolic acid comprising (i) 5-methyl-(6S)-tetrahydrofolic acid, (ii) sodium and (iii) an organic base having a pKa value from 6 to 11; wherein the molar ratio of 5-methyl-(6S)-tetrahydrofolic acid to the sodium is from 1:0.5 to 1:1.5 and the molar ratio of 5-methyl-(6S)-tetrahydrofolic acid to the organic base is 1:0.5 to 1:1.5 and/or hydrates and/or solvates thereof, as well as, a processes of obtaining the same. |
| US11066405B2 |
Bicyclic compounds and their use in the treatment of cancer
The present disclosure is directed to novel compounds of Formula I and pharmaceutically acceptable salts, solvates, solvates of the salt and prodrugs thereof, useful in the prevention (e.g., delaying the onset of or reducing the risk of developing) and treatment (e.g., controlling, alleviating, or slowing the progression of) of cancer, including glioblastoma, bone cancer, head and neck cancer, melanoma, basal cell carcinoma, squamous cell carcinoma, adenocarcinoma, oral cancer, esophageal cancer, gastric cancer, intestinal cancer, colon cancer, bladder cancer, hepatocellular carcinoma, renal cell carcinoma, pancreatic cancer, ovarian cancer, cervical cancer, lung cancer, breast cancer, and prostate cancer. The compounds of the disclosure are selective antagonists of the EP4 receptor and useful treatment of various diseases that may be ameliorated with blockade of PGE2-mediated signaling. |
| US11066404B2 |
Dihydropyrido[2,3-d]pyrimidinone compounds as CDK2 inhibitors
The present application provides dihydropyrido[2,3-d]pyrimidone inhibitors of cyclin-dependent kinase 2 (CDK2), as well as pharmaceutical compositions thereof, and methods of treating cancer using the same. |
| US11066403B2 |
Solid form of azetidine derivative and preparation method therefor and use thereof
The present invention relates to a solid form of a compound of Formula (I), a method for preparing the solid form, a pharmaceutical composition comprising the solid form, and use of the solid form in the treatment of Janus kinase (JAK) related diseases comprising, for example, inflammatory diseases, autoimmune diseases, and cancers. |
| US11066401B2 |
Pyrimidine compound, chloride salt thereof, and manufacturing and application of same
The present invention relates to a pyrimidine compound, a chloride salt thereof, and a manufacturing and application of same. The chloride salt of the pyrimidine compound is presented by formula (II). The chloride salt has higher solubility, good stability, higher bioavailability, and very low hygroscopicity, and has excellent inhibition against a PIM kinase. |
| US11066400B2 |
Compounds for the treatment of cancer
The present invention relates to a FoxM1 gene splicing modifier selected from a compound of formula (I) or of formula (VI) wherein A and B are as defined herein, or a pharmaceutically acceptable salt thereof, for use in the treatment, prevention and/or delay of progression of cancer. |
| US11066399B2 |
Ferroportin inhibitors
The invention relates to novel compounds of the general formula (I), with Het-2 being an optionally substituted bicyclic heteroaryl of the formula pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for the use as ferroportin inhibitors, more particularly for the use in the prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, such as particularly iron overload states such as in particular thalassemia and hemochromatosis. |
| US11066393B2 |
Indolin-2-one derivatives
The present invention is concerned with indolin-2-one derivatives of general formula wherein the substituents are defined in claim 1. The compounds may be used in the treatment of CNS diseases related to positive (psychosis) and negative symptoms of schizophrenia, substance abuse, alcohol and drug addiction, obsessive-compulsive disorders, cognitive impairment, bipolar disorders, mood disorders, major depression, treatment resistant depression, anxiety disorders, Alzheimer's disease, autism, Parkinson's disease, chronic pain, borderline personality disorder, neurodegenerative disease, sleep disturbances, chronic fatigue syndrome, stiffness, inflammatory disease, asthma, Huntington's disease, ADHD, amyotrophic lateral sclerosis, effects in arthritis, autoimmune disease, viral and fungal infections, cardiovascular diseases, ophthalmology and inflammatory retinal diseases and balance problems, epilepsy and neurodevelopmental disorders with co-morbid epilepsy. |
| US11066388B2 |
Indazole-3-carboxamides and their use as WNT/B-catenin signaling pathway inhibitors
Indazole-3-carboxamide compounds for treating various diseases and pathologies are disclosed. More particularly, the present invention concerns the use of an indazole-3-carboxamide compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states. |
| US11066387B2 |
Salts of a Pim kinase inhibitor
The present invention relates to salt forms of the Pim kinase inhibitor N-{(7R)-4-[(3R,4R,5S)-3-amino-4-hydroxy-5-methylpiperidin-1-yl]-7-hydroxy-6,7-dihydro-5H-cyclopenta[b]pyridin-3-yl}-6-(2,6-difluorophenyl)-5-fluoropyridine-2-carboxamide, including methods of preparation thereof, and intermediates in the preparation thereof, where the compound is useful in the treatment of Pim kinase-related diseases such as cancer. |
| US11066384B2 |
Crystalline forms of ARN-509, preparation method and use thereof
The present disclosure relates to novel crystalline forms of ARN-509 (structure shown in formula I), processes for preparation of the novel crystalline forms, pharmaceutical composition of the novel crystalline forms, and uses of the novel crystalline forms for preparing drug products of androgen receptor antagonists and for treating prostate cancer. The crystalline forms of ARN-509 provided by the present disclosure have one or more improved properties compared with the prior art, and is of great value to the future optimization and development of drugs. |
| US11066382B2 |
Organic compound and organic electroluminescent device comprising same
The present disclosure relates to a novel compound, and an organic electroluminescent device including the same, and by using the compound according to the present disclosure in an organic material layer, preferably a light emitting layer or an auxiliary light emitting layer, of an organic electroluminescent device, light emission efficiency, a driving voltage, a lifetime and the like of the organic electroluminescent device may be enhanced. |
| US11066376B2 |
Production of purified dialkyl-furan-2,5-dicarboxylate (DAFD) in a retrofitted DMT plant
Disclosed is a process to produce a purified vapor comprising dialkyl-furan-2,5-dicarboxylate (DAFD). Furan-2,5-dicarboxylic acid (FDCA) and an alcohol in an esterification zone to generate a crude diester stream containing dialkyl furan dicarboxylate (DAFD), unreacted alcohol, 5-(alkoxycarbonyl)furan-2-carboxylic acid (ACFC), and alkyl furan-2-carboxylate (AFC). The esterification zone comprises at least one reactor that has been previously used in an DMT process. |
| US11066373B2 |
Morphic forms of hexadecyloxypropyl-phosphonate esters and methods of synthesis thereof
The disclosure describes methods of synthesis of phosphonate ester compounds. The methods according to the disclosure allow for large-scale preparation of phosphonate ester compounds having high purity and stability. Also disclosed are morphic forms of phosphonate ester compounds. |
| US11066360B2 |
Human plasma kallikrein inhibitors
Disclosed are compounds of formula I, and pharmaceutically acceptable salts thereof. The compounds are inhibitors of plasma kallikrein. Also provided are pharmaceutical compositions comprising at least one compound of the invention, and methods involving use of the compounds and compositions of the invention in the treatment and prevention of diseases and conditions characterized by unwanted plasma kallikrein activity. |
| US11066359B2 |
Biodegradable surfactants and related compositions, methods and systems
Biodegradable surfactants are described, in which an amphiphilic heteroatom containing hydrocarbon optionally comprising at least one counterion (Z), and related compositions, methods and systems. Biodegradable surfactant described herein has an aHLB value in accordance with equation (1): aHLB=20*Gh/(Gh−Gt) (1) wherein Gh is the Group Number of a hydrophilic head portion of the biodegradable surfactant optionally comprising the at least one counterion (Z), and Gt is the Group Number of a hydrophobic tail portion of the biodegradable surfactant. A biodegradable surfactant in the sense of the disclosure can be tuned to a set hydrophilic-lipophilic balance (aHLB) by selectively modifying at least one tuning moiety of the biodegradable surfactants to provide tuned biodegradable surfactants having an increase or decrease in their adjusted hydrophilic-lipophilic balance (aHLB). |
| US11066356B2 |
Device and method for the desalination of water by means of thermal deionisation and liquid-phase ion extraction liquid
Disclosed is a method for treating water, including the extraction of at least two ionic species, the ionic species including an anionic species and a cationic species and being present in the water to be treated, the method especially including a step of mixing a liquid hydrophobic organic phase and the water to be treated, the water to be treated being in the liquid state, in order to subsequently obtain liquid treated water and a hydrophobic liquid organic phase loaded with the ionic species, and a step of thermal regeneration of the organic phase loaded with chemical species. Also disclosed are compounds and compositions that can be used in the method. |
| US11066351B2 |
Organic compound, three-dimensional organic framework formed by using organic compound, separation sieve and optical layer, which comprise organic framework, and optical device comprising optical layer as optical amplification layer
An organic compound, a three-dimensional organic structure formed by using the organic compound, a separation sieve and an optical layer having the organic structure, and an optical device having the optical layer as an optical amplification layer are provided. The organic structure includes a plurality of organic molecules self-assembled by non-covalent bonding. Each of the unit organic molecules has an aromatic ring, a first pair of substituents being connected to immediately adjacent positions of substitutable positions of the aromatic ring, and a second pair of substituents being connected to immediately adjacent positions of remaining substitutable positions of the aromatic ring. The unit organic molecules are self-assembled by van der Waals interaction, London dispersion interaction or hydrogen bonding between the first and the second pairs of the substituents and by pi-pi interactions between the aromatic rings. |
| US11066349B2 |
Method for separating essential oils from biomass
Essential oils, such as CBD oil, are extracted from biomass, such as hemp, in a continuous process. The biomass is delivered to the upper end of a vertically oriented extraction chamber, while a solvent is injected at the lower end thereof. As the solvent flows upwardly, the oil is removed from the biomass. The resulting liquor is collected and purified. |
| US11066345B2 |
Processes for increasing an octane value of a gasoline component
Processes for increasing an octane value of a gasoline component by dehydrogenating a stream comprising C7 hydrocarbons and methylcyclohexane in a first dehydrogenation zone to form an intermediate dehydrogenation effluent, and then dehydrogenating the intermediate dehydrogenation effluent in a second dehydrogenation zone to form a C7 dehydrogenation effluent. The C7 dehydrogenation effluent has an increased olefins content compared to an olefins content of the intermediate dehydrogenation effluent. The first dehydrogenation zone is operated under conditions to convert methylcyclohexane to toluene and minimize cracking reactions. The intermediate dehydrogenation effluent may be heated before being passed to the second dehydrogenation zone. |
| US11066340B2 |
Fertilizers containing slow and fast release sources of boron
A granular fertilizer product having at least two sources of boron having different solubilities to tailor boron availability during the entire growing season of a plant, while reducing the risk of boron toxicity. A first source of boron can include a sodium-based or highly water soluble boron compound such as sodium tetraborate and/or boric acid, while a second source of boron can include a calcium-based boron compound such as colemanite (CaB3O4(OH)3.(H2O)) (e.g. when the carrier fertilizer is N- or K-based) and/or boron phosphate (BPO4) (e.g. when the carrier fertilizer is P-based). The solubility of the first source of boron is higher than the solubility of the second source of boron such that the sources of boron have different release rates into the soil. |
| US11066338B2 |
Antimicrobial glaze and porcelain enamel via double layer glaze with high zinc content
A cost-effective and practical antimicrobial glaze system and glazing process is disclosed herein. The antimicrobial glaze/enamel may comprise at least two layers: a base layer and a top layer. The base layer may contain a typical or normal glaze widely used in sanitary ware, having a low level of zinc oxide. The base layer glaze may be directly sprayed on the clay body surface. A thin top glaze layer is sprayed on top of the base glaze layer and the top layer may contain a high level of zinc oxide. |
| US11066337B2 |
Inorganic foam based on calcium sulfoaluminate
The present invention relates to a process for preparing a particle-stabilized inorganic foam based on calcium sulfoaluminate, to a particle-stabilized inorganic foam based on calcium sulfoaluminate, to a cellular material obtainable by hardening and optionally drying the particle-stabilized inorganic foam based on calcium sulfoaluminate, and to a composition for preparing an inorganic foam formulation for providing a particle-stabilized inorganic foam based on calcium sulfoaluminate. |
| US11066328B2 |
Low reflectivity coating and method and system for coating a substrate
A low reflectivity coating (20) is formed of a layer of carbon nanostructures (20) over a contact surface (14) of a substrate (10), from a spray incorporating the carbon nanostructures in suspension in a solvent. The carbon nanostructure layer provides a very low reflectivity coating which may be further enhanced by etching the outer surface of the coating. The layer may be etched for reduced reflectivity. Very low reflectivity coatings have been achieved. |
| US11066326B2 |
Glass
A glass of the present invention includes as a glass composition, in terms of mass %, 55% to 70% of SiO2, 15% to 25% of Al2O3, 1% to 5% of B2O3, 0% to 0.5% of Li2O+Na2O+K2O, 0% to 4% of MgO, 3% to 11% of CaO, 0% to 4% of SrO, and 0% to 11% of BaO, and has a strain point of more than 715° C. |
| US11066325B2 |
Alkali-free glass
To provide an alkali-free glass having a high specific elastic modulus, a suitable strain point, a low density, a not too low thermal expansion coefficient, a good clarity and a good solubility.An alkali-free glass, which comprises, as represented by mol % based on oxides, SiO2: 62 to 70%, Al2O3: 11 to 14%, B2O3: 3 to 6%, MgO: 7 to 10%, CaO: 3 to 9%, SrO: 1 to 5% and BaO: 0 to 1%, wherein [SiO2]+0.7[Al2O3]+1.2[B2O3]+0.5[MgO]+0.4[CaO]−0.25[SrO]−0.88[BaO] is at least 85, [SiO2]+0.45[Al2O3]+0.21[B2O3]−0.042[MgO]+0.042[CaO]+0.15[SrO]+0.38[BaO] is from 72 to 75, 0.4[SiO2]+0.4[Al2O3]+0.25[B2O3]−0.7[MgO]−0.88[CaO]−1.4[SrO]−1.7[BaO] is at most 19, the specific modulus is at least 32 MN·m/kg, the strain point is from 690 to 710° C., the density is at most 2.54 g/cm3, the average thermal expansion coefficient at from 50 to 350° C. is at least 35×10−7/° C., and the temperature T2 at which the glass viscosity reaches 102 dPa·s is from 1,610 to 1,680° C. |
| US11066320B2 |
Cover glass and a manufacturing method thereof using glass wool
A method of manufacturing a cover glass is provided. The method comprises providing a glass base; forming a glass support portion by printing glass onto the glass base; and applying glass wool onto the glass support portion. |
| US11066318B2 |
Green glass composition
Embodiments relate to a green glass composition, which can reduce the cooling load of a building and a vehicle by effectively lowering solar heat ray and ultraviolet ray transmittance while ensuring a high visible light transmittance suitable for window glass without using a coloring agent such as Ce, Co and Cr, and also has excellent bubble quality; green glass manufactured therefrom; and a method for manufacturing green glass. According to at least one embodiment, there is provided a green glass composition including 0.65-1.3 wt % of Fe2O3, 0.1-0.4 wt % of TiO2, and 0.05-0.20 wt % of SO3, based on 100 wt % of a soda lime mother glass composition, wherein an oxidation-reduction ratio of Fe2O3 is 0.22 to 0.38. |
| US11066316B2 |
Treatment of oil and grease in water using algae
A method for treating an oil-containing medium including oil or grease or both oil and grease includes the steps of combining algae with an oil-containing medium and allowing the algae to engulf or uptake at least a portion of the oil or grease in the oil-containing medium. A mixture for treating oil or grease or both oil and grease includes an oil-containing medium including oil or grease or both oil and grease and phagotrophic algae that engulf or uptake at least a portion of the oil or grease in the oil-containing medium. |
| US11066314B2 |
Water treatment aerator having bubble diffuser
An aerator assembly for wastewater treatment includes a draft tube and an air supply assembly. The draft tube includes a sidewall and presents open top and bottom tube ends. The air supply assembly includes an air supply conduit and a diffuser body. The diffuser body has an inlet aperture and a bubble generator connected to the inlet. The inlet aperture is connected to the air supply conduit such that the bubble generator receives air from a source of air, to which the air supply conduit is connected. The bubble generator has a plurality of air openings for generating fine air bubbles. The diffuser body is sealingly engaged to the sidewall adjacent the bottom tube end so as restrict upward flow of wastewater through the draft tube past the diffuser body. |
| US11066313B1 |
Methods for removing anions from water
Methods are disclosed for treating water containing a target anion to remove the target anion. The methods can include preparing a treatment composition solution that contains a metal treatment agent, adjusting the treatment composition solution to a first pH that is alkaline and then to a second pH that is acidic, and contacting the treatment composition solution with the water that contains the target anion. |
| US11066312B2 |
Method and apparatus for separating low density particles from feed slurries
In a method and apparatus for separating low density particles from feed slurries, a bubbly mixture is formed in a downcomer and issues into a mid region in a chamber. An inverted reflux classifier is formed by parallel inclined plates below the mid region allowing for efficient separation of low density particles which rise up to form a densely packed foam in the top of the chamber, and denser particles which fall downwardly to an outlet. |
| US11066310B2 |
Tungsten pentachloride conditioning and crystalline phase manipulation
Conditioning of tungsten pentachloride to form specific crystalline phases is disclosed. The specific crystalline phases permit stable vapor pressures over extended periods of time during vapor deposition and etching processes. |
| US11066309B2 |
Direct synthesis of high-aspect ratio zeolite nanosheets
An example material includes a planar layer of MFI zeolite. The planar layer has a thickness in a range between 4 nm and 10 nm for at least 70% of a basal area of the planar layer. In one embodiment, the planar layer includes an embedded particle of an MFI zeolite. |
| US11066302B2 |
Method for producing inorganic oxide in form of thin film
Provided is a method for producing an inorganic oxide in the form of a thin film, the method including a step of bringing a first liquid and a second liquid into contact with each other, the first liquid having an inorganic oxide precursor dissolved therein, the second liquid phase-separating from the first liquid and having a substance dissolved therein, the substance reacting with the inorganic oxide precursor of the first liquid to form an inorganic oxide derived from the inorganic oxide precursor. The segment size of the first liquid at the time of contact between the first and second liquids is 500 μm or smaller. |
| US11066296B1 |
Methods, apparatus, and systems for fabricating solution-based conductive 2D and 3D electronic circuits
This work develops a novel microfluidic method to fabricate conductive graphene-based 3D micro-electronic circuits on any solid substrate including, Teflon, Delrin, silicon wafer, glass, metal or biodegradable/non-biodegradable polymer-based, 3D microstructured, flexible films. It was demonstrated that this novel method can be universally applied to many different natural or synthetic polymer-based films or any other solid substrates with proper pattern to create graphene-based conductive electronic circuits. This approach also enables fabrication of 3D circuits of flexible electronic films or solid substrates. It is a green process preventing the need for expensive and harsh postprocessing requirements for other fabrication methods such as ink-jet printing or photolithography. We reported that it is possible to fill the pattern channels with different dimensions as low as 10×10 μm. The graphene nanoplatelet solution with a concentration of 60 mg/mL in 70% ethanol, pre-annealed at 75° C. for 3 h, provided ˜0.5-2 kOhm resistance. The filling of the pattern channels with this solution at a flow rate of 100 μL/min created a continuous conductive graphene pattern on flexible polymeric films. The amount of graphene used to coat 1 cm2 of area is estimated as ˜10 μg. A second method regarding the transfer of graphene material-based circuits with small features size (5 μm depth, 10 μm width) from any solid surface to flexible polymeric films via polymer solvent casting approach was demonstrated. This method is applicable to any natural/synthetic polymer and their respective organic/inorganic solvents. |
| US11066295B2 |
Micromechanical component having an oscillator, a method for the manufacture thereof, and a method for exciting a motion of an adjustable element about a rotational axis
A micromechanical component having a mount, an adjustable element, which is connected via at least one spring to the mount, and an actuator device, a first oscillatory motion of the adjustable element about a first axis of rotation and simultaneously a second oscillatory motion of the adjustable element, which is set into the first oscillatory motion, being excitable about a second axis of rotation in response to the actuator device; and the adjustable element being configured by the at least one spring to be adjustable on the mount in such a way that the adjustable element is adjustable by a resulting angular momentum about a rotational axis, which is oriented orthogonally to the first axis of rotation and orthogonally to second axis of rotation. Also, a method for manufacturing a micromechanical component. Moreover, a method for exciting a motion of an adjustable element about a rotational axis. |
| US11066289B2 |
Keg closure with attached venting system
A closure (1) for a beverage keg (90), comprising an inlet for admitting a pressurised gas into a headspace of the beverage keg (90) and a venting aperture (27) separate from the inlet. The venting aperture (27) is configured to provide fluid communication between the headspace of the keg (90) and an exterior of the closure (1). The closure (1) is provided with a barrier (29) that is welded to the closure (1) and configured to seal the venting aperture such that the closure (1) is able to retain the pressurised gas within the keg (90) in an unvented configuration. The barrier (29) is configured to rupture and/or to become at least partially detached from the closure (1) by internal pressure from within the keg (90) in order to switch the closure (1) into a vented configuration in which the venting aperture (27) is no longer sealed by the barrier (29). |
| US11066288B2 |
Systems and methods for dispensing a beverage stored in a collapsible beverage container
A beverage dispensing system (10) for dispensing a beverage stored in a collapsible beverage container (18) comprising a base part (14), a beverage container connector for connecting to a beverage outlet of said collapsible beverage container (18), and a lid (12) connectable to said base part (14), in which said lid (12) and said base part (14) define a sealed inner space (16) for accommodating and encapsulating said collapsible beverage container (18), and in which said beverage dispensing system (10) further comprises a vacuum pump (32) in fluid communication with said inner space (16), thereby collapsing said collapsible beverage container (18) and forcing said beverage out of the collapsible beverage container (18) through a tapping line (26) and out through a tapping device (28). |
| US11066285B2 |
Dispensing apparatus for aging and storing wine in flexible containers
A system is provided for dispensing and storing liquid, such as wine. The system may include a dip tube coupled to a flexible bladder in an airtight manner. The dip tube may include a dip tube head and a perforated dip tube extension extending from the dip tube head into the contents of the flexible bladder. |
| US11066282B2 |
System and method for maneuvering a mobile drive unit
A mobile drive unit is provided for transporting an inventory holder. The mobile drive unit is operable to dock with the inventory holder, move the inventory holder in a first translational direction, and while docked with the inventory holder, selectively rotate the inventory holder while continuing to move in the first translational direction. |
| US11066281B2 |
Construction machine
A construction machine allows a worker to easily move between one pair of side frames through a travelling body weight. The construction machine includes a lower travelling body of a crane includes a truck frame, a left side frame and a right side frame, a front weight and a rear weight, and scaffolding members. Scaffolding upper surface parts of the scaffolding members and upper surface parts of the front weight and the rear weight are disposed in line with each other along a left and right direction, and form a moving passage that allows the worker to move between the left and right side frames. |
| US11066280B2 |
Container crane control system
A container crane control system including: a camera configured to be fixedly mounted to a crane to obtain a series of captured images, a video output configured to provide a video signal including a series of cropped image based on the series of captured images; and a control device configured to, for at least part of the captured images and the respective cropped image, receive an input signal indicating a current height of a load of the crane, wherein the control device is configured to control a position of the respective cropped image within the captured image based on the current height of the load. |
| US11066279B2 |
Motion compensating crane for use on an offshore vessel
A motion compensating crane for use on an offshore vessel having a hull with a design waterline, wherein the crane includes a revolving superstructure, a main boom mounted to the revolving superstructure and pivotally connected at an inner end thereof about a substantially horizontal boom pivot axis to the revolving superstructure, the main boom having a tip end remote from the inner end, a main boom luffing assembly adapted to set an angle of the main boom relative to the superstructure within a main boom working angle range, a rigid jib frame pivotally connected to the tip end of the main boom about a substantially horizontal jib frame pivot axis, and a level setting assembly adapted to set the rigid jib frame in a levelled position whilst the main boom has an angle within the main boom working angle range. The rigid jib frame is provided with a set of parallel X-direction tracks which are substantially horizontal in the levelled position of the rigid jib frame. The crane further has a mobile carrier supported by the X-direction tracks and movable by a motor powered X-motion displacement actuator assembly. The mobile carrier is provided with one or multiple parallel Y-direction tracks and a mobile jib hoist cable suspension member is supported by the one or more Y-direction tracks and movable relative thereto. |
| US11066274B2 |
Electromagnetic safety trigger
The present disclosure relates generally to a selectively operable safety brake including a magnetic brake operably coupled to a rod and disposed adjacent to a metal component, the magnetic brake configured to move between an engaging position and a non-engaging position, said magnetic brake, when in the engaging position contemporaneously with motion of the machine, moving the rod in to thereby move the safety brake from the non-braking state into the braking state, and an electromagnetic component including a retention apparatus, the electromagnetic component configured to move the magnetic brake from the engaging position to the non-engaging position upon receipt of a resetting signal. |
| US11066273B2 |
Elevator overtravel testing systems and methods
Elevator systems having a first guide rail and a second guide rail, an overtravel feature on at least one of the first or second guide rails, the overtravel feature located a first distance from a top surface of the respective guide rail, an elevator car moveable along the first and second guide rails, the elevator car including a car guidance element, and a control unit configured to perform an overtravel distance test. The control unit is configured to measure a second distance being a distance of travel of the elevator car between a landing position and a location of the overtravel feature, combine the first distance and the second distance to calculate a measured overtravel distance, and compare the measured overtravel distance with a predetermined overtravel setpoint. |
| US11066272B2 |
Cable storage and handling systems and methods
An assembly and method for deploying, retrieving, and storing a cable having a minimum bend radius onto a drum. The assembly may comprise a frame, a rotatable drum carried by the frame, a levelwind carried by the frame, and a powertrain. The levelwind may comprise a rail spanning at least the width of the drum, and a traversable carriage carried by the rail. The levelwind may also comprise a cable guide carried by the carriage, where the cable guide comprises an elongated chute having contoured walls. The contoured walls of the chute include no bends having a radius less than the minimum bend radius of the cable. The powertrain may be operatively connected to rotate the drum about the drum axis and traverse the carriage along the rail. In some examples, the contoured walls of the chute are coated with a supplmentary coating. |
| US11066270B2 |
Sheet folding apparatus and image forming apparatus
Provided is a sheet folding apparatus for folding sheets, including: a feeding-roller pair; a loop-forming space provided downstream from the feeding-roller pair, for forming a sheet loop; a pushing member for pushing the looped sheet; a folding-roller pair for nipping a prescribed part of the sheet pushed by the pushing member, thereby to fold the sheet; and a path provided between the feeding-roller pair and the folding-roller pair, for guiding the sheet fed from the feeding-roller pair toward the loop-forming space. |
| US11066269B2 |
Sheet folding processing apparatus and image forming system including the same
A sheet folding processing apparatus suppresses an increase in size and cost of the apparatus and performs folding processing on continuously conveyed sheets. In the sheet folding processing apparatus, a sheet conveyed by a feeding roller pair and hang in a loop shape in a loop forming space is pushed into a nipping portion of a folding roller pair by a pushing plate, so that the sheet is folded in a Z-shape to form a plurality of fold lines. The sheet is conveyed in the conveyance direction until the sheet rear end passes through the feeding roller pair, and after the sheet rear end is stored in a loop forming space by moving the pushing plate from a position for pushing the sheet into a nipping portion to a retracting position, the reinforcing processing of the fold line of the sheet is performed by an additional folding unit. |
| US11066267B2 |
Recording material processing apparatus or image forming system each of which executes stapling process
A recording material processing apparatus includes a processing tray, a detecting unit, a stapling unit, an instructing unit, a control unit, a switching unit, and a notifying unit. The detecting unit detects recording material placed in the processing tray. The stapling unit executes a stapling process for the recording material placed in the processing tray. The instructing unit outputs a stapling process execution instruction. Upon receipt of the execution instruction in a state in which the detecting unit has detected a recording material inserted in the processing tray from an outside of a main body of a main body apparatus, the control unit cause the stapling process to be executed. The switching unit switches a position of the stapling unit among a plurality of positions. The notifying unit provides notification of a placement position of the recording material in the processing tray corresponding to each of the plurality of positions. |
| US11066265B2 |
Value note cassette
A value note cassette includes a first storage area for storing first notes of value of a first value note type. The first notes of value are storable in the first storage area in a first orientation. The value note cassette also includes a second storage area for storing second notes of value of a second value note type. The second storage area is separate from the first storage area. The second notes of value are storable in the second storage area in a second orientation. The first orientation is orthogonal to the second orientation. |
| US11066260B2 |
Sheet loading device and image forming apparatus incorporating the sheet loading device
A sheet loading device includes a device body to load a sheet, a guide disposed extending in a sheet conveying direction in the device body, a restricting body to move along the guide of the device body and to restrict a position of an end portion of the sheet, and a securing body to attach to the restricting body and the guide and detach from the restricting body and the guide, and having an engaging body. The engaging body of the securing body engages with the guide at an arbitrary position on the guide in the sheet conveying direction. The restricting body is being secured to the device body according to engagement of the engaging body of the securing body with the guide of the device body. |
| US11066254B1 |
Distribution ramp for dry agricultural product applicator
A distribution ramp system for a dry product applicator with a pneumatic conveyance system is provided which lifts product that drags along a bottom surface(s) of a delivery line's wall(s) back into a main central or primary airflow portion that carries the product downstream through the pneumatic conveyance system. The system may include a ramp that nests against a bottom wall of the delivery line with a narrow front and wide back so the ramp presents a gradual wedge facing toward the incoming upstream airflow entrained with particulate material of the product, urging particulate material dragging on the bottom wall to lift away from the bottom wall and toward reentry into the primary airflow portion. |
| US11066251B2 |
Board conveyor
A conveyor for transporting a board along a path in a transport direction has an upstream section, a downstream section aligned with the upstream section and defining therewith a horizontal support plane, and a center section between the upstream and downstream sections. The center section is movable from a pass-through position aligned and level with the upstream and downstream sections to an offset position spaced therefrom horizontally or vertically. A platform underneath the center section is moveable vertically, and a lift moves the platform vertically between upper and lower positions. Hooks or grab can, when the center section is in the offset position and the platform is in the lower position, either pull a board off the platform and onto the downstream section or guide and deposit a board from the upstream section onto the platform. |
| US11066248B2 |
Article transport device
The article transport device includes a transport vehicle configured to move back and forth between a receiving location and a delivery location, and a load receiving base that is provided at at least the receiving location. The transport vehicle includes a transport placing base on which an article is to be placed, and a lift device configured to raise and lower the transport placing base to a first height and to a second height that is lower than the first height. The load receiving base is a base on which an article is to be placed, and is fixed at a third height that is between the first height and the second height. When the transport vehicle performs restoration movement to move from the delivery location to the receiving location, the lift device performs a restoration operation that differs in accordance with whether or not an article is present on the load receiving base at the receiving location. |
| US11066247B2 |
Powersweep including gearbox shifter mechanism
A gearbox below a grain bin floor can have a shift coupling movable between a drive position and a neutral position. A control rod can be axially movable between a corresponding drive position and a corresponding neutral position. A pair of biasing members can be operably positioned between the control rod and the shift coupling to bias the shift coupling in opposite directions. The opposite biasing forces of the biasing members can act against each other to bias the control rod into the neutral positioning recess to retain the external shift coupling and the control rod in the neutral position and the corresponding neutral position, respectively. The opposite biasing force of the biasing members can bias the control rod into the drive positioning recess to retain the external shift coupling and the control rod in the drive position and the corresponding drive position, respectively. |
| US11066245B2 |
Conveyor truss elevation apparatus, systems, and methods
Conveyor elevation apparatus, systems and methods are provided. Some embodiments include a stmt having three frame sections. In some embodiments at least two of the frame sections comprise longitudinal supports joined by bracing. |
| US11066243B2 |
Method and system for conveying articles and an apparatus for doing the same
A conveyor for transporting and elevating articles and a method and system for conveying articles up inclines is provided. The conveyor has a conveyor belt and a plurality of support elements extending outward from the article-conveying surface of the conveyor belt advancing upward along the incline. The conveyor may be positioned at an inclined angle relative to the horizontal ground, i.e., between about 5° and 85° or the conveyor can be substantially vertical, i.e., about 90° relative to the horizontal ground. The support elements prevent conveyed articles from sliding down the conveyor belt on the inclined conveyor and carry and hold articles on substantially vertical conveyors. The article-conveying surface of the conveyor belt may provide a low-friction retention surface to articles leaning away from the conveyor belt on the incline. |
| US11066239B2 |
Methods, systems and apparatus for controlling movement of transporting devices
A system and method for controlling movement of at least one transporting device arranged to transport containers in stacks arranged in a facility, the facility having pathways arranged in a grid-like structure above the stacks, the at least one transporting device being configured to operate on the grid-like structure, the system. A receiving unit is configured to receive information about a product to be returned to a container in a stack, wherein the product is located at a workstation; and a control unit is configured to select a container located in the stacks into which the product is to be placed and instruct a transporting device to move the selected container to a location of the workstation. |
| US11066235B2 |
Garbage can riser system
A garbage can riser system for facilitating a flip lid on a garbage can to be opened when the garbage can is full includes a garbage can that has a top end. A riser is provided and the riser is positionable on the top end of the garbage can for increasing a functional height of the garbage can. A flip lid is positionable on the riser such that the flip lid is spaced above garbage contained in the garbage can. In this way the entire volume of the garbage can be filled with garbage without having the flip lid contacting the garbage when the flip lid is opened. |
| US11066233B2 |
Foldable container
A foldable container, comprising a base and two pairs of side plates, and the side plates are connected to the base via a hinge structure. A plurality of protruding portions are disposed below the side plates, and a polarity of grooves matching the protruding portions are disposed on the base. The hinge structure is disposed in at least one of the protruding portions and at least one of grooves. At least one of the protruding portions is further provided with a continuous curved surface profile, and at least one of the grooves is further provided with at least one matching surface, or at least one of the grooves is provided with a continuous curved surface profile, and at least one of the protruding portions is provided with a matching surface. The matching surface matches the continuous curved surface profile, and when the side plate changes from a folded state to the open state, the continuous curved surface profile remain contacting with the matching surface. The foldable container can address the problems of interference and collision in a process of unordered rotation of hinged side plates. |
| US11066218B2 |
Discharge head, and liquid dispenser comprising such a discharge head
Discharge head for a liquid dispenser including a housing, a coupling device for attachment to a liquid store, a discharge opening through which liquid is dispensed and an outlet channel extending from an inlet region, pointing in the direction of the liquid store, up to the discharge opening and via which the discharge opening is supplied with liquid. A throttle device is arranged in the outlet channel and includes a throttle channel for reducing liquid pressure and/or liquid flow through the throttle device. The throttle device is designed in the form of a dynamic throttle device, in which a free cross section of the throttle channel is reduced in size with increasing pressure prevailing at the throttle device, or with greater liquid flow flowing through the throttle device. |
| US11066211B1 |
Collapsible capsules and supplemental devices
A collapsible capsule including a first annular body portion having a first annular body portion proximal end, a first annular body portion distal end and a first annular body portion diameter, the first annular body portion proximal end comprises an opening, a second annular body portion having a second annular body portion proximal end, a second annular body portion distal end and a second annular body portion diameter that is smaller than the first annular body portion diameter, the second annular body portion distal end is a closed end, and an intermediate annular body portion extending from the first annular body portion distal end to the second annular body portion proximal end. |
| US11066209B2 |
Convenient solid product dispensing package
A blank used to form a hexagonal shaped box, the blank having a front sidewall and a back sidewall, a first sidewall having a first sidewall top flap and a first sidewall bottom flap, a second sidewall having a second sidewall top flap and a second sidewall bottom flap, a second sidewall bottom flap extension foldably connected to the second sidewall bottom flap, a third sidewall having a third sidewall top panel, a fourth sidewall having a fourth sidewall top flap and a fourth sidewall bottom flap, a fourth sidewall bottom flap extension foldably connected to the fourth sidewall bottom flap, an inner sidewall foldably connected to the fourth sidewall, an inner sidewall flap foldably connected to the inner sidewall, a top panel including an aperture for dispensing food product there through, a bottom panel foldably connected to the front sidewall, and a slide foldably connected to the front sidewall. |
| US11066203B2 |
Automatic alignment and label attaching apparatus for test tube
Provided is a test tube automatic alignment and label attaching apparatus including a basket formed in a box shape and whose upper surface is open to receive a plurality of test tubes and having a concave bottom surface; a test tube supply device mounted inside the basket and configured to discharge test tubes received in the basket to one side of the basket; and a test tube feeder configured to move the test tubes discharged from one side of the basket. Various other embodiments are available. |
| US11066199B2 |
Method and device for forming container groupings
Provided is a method for packaging piece good groupings, in which a plurality of piece goods, particularly containers, are at least partially interconnected by a first connector, wherein at least two-piece goods of this plurality are directly interconnected by the connector. According to the embodiment, this plurality of piece goods connected by the connector is packaged with a second connector in the form of a second wrapping element, and said plurality of piece goods connected by a first connector is conveyed by a conveyor device to a packaging device and enclosed, particularly wrapped, with the second wrapping element by said packaging unit. |
| US11066194B2 |
Method for the safe release of artificial satellites in earth's orbit
A method for the safe release of artificial satellite in Earth orbit includes the steps of providing an orbital transport spacecraft able to move at orbital height and comprising a plurality of PODs for releasing satellites transported by the orbital transport spacecraft, housing said orbital transport spacecraft in a space launcher configured to reach an orbital height; generating a release signal and transmitting it to the orbital transport spacecraft to release the orbital transport spacecraft from the space launcher, in case of failure to release the orbital transport spacecraft or in case of breakdown of the orbital transport spacecraft after releasing from the space launcher, activating a safety subsystem of the orbital transport spacecraft to generate a POD activation sequence to release the satellites. |
| US11066192B2 |
Satellite deployer door with clutch bearing
A satellite dispenser door assembly is disclosed. In various embodiments, a satellite dispenser door assembly as disclosed herein includes a dispenser door having a hinge pin; and a one way clutch bearing within which the hinge pin is free to rotate in a first rotational direction associated with a transition from a closed position of the dispenser door to an open position of the dispenser door. |
| US11066187B2 |
Transport jig
A transport jig includes: a frame member; and a support section that is installed on the frame member and that supports a plurality of elongated members. The elongated members are each entirely housed inside the frame member in a lengthwise direction and the support section supports the plurality of elongated members in parallel with one another in one direction. |
| US11066186B2 |
Receiving appliance for automated deliveries
A landing pad receives and stores packages delivered from an aerial vehicle and awaiting pickup from an aerial vehicle. The landing pad can be placed outside of a window and can contain a transmitter for sending out an identification signal via radio frequency to aid aerial vehicles in finding the landing pad. The landing pad contains a landing platform with a trapdoor that leads to a storage compartment. The trapdoor can be configured to only open when it receives a signal from an authorized aerial vehicle. The storage compartment can be accessed via a storage compartment door which can contain a locking mechanism. The storage compartment can be climate controlled. The landing pad can also have a transmitter that emits sounds to discourage animals from nesting on or near the landing pad. The landing pad can also include a solar power generator as a source of electrical energy. |
| US11066185B2 |
Launch and/or recovery for unmanned aircraft and/or other payloads, including via parachute-assist, and associated systems and methods
Launch and/or recovery for unmanned aircraft and/or other payloads, including via parachute-assist, and associated systems and methods are disclosed. A representative method for lofting a payload includes directing a lifting device upward, releasing a parachute from the lifting device, with the parachute carrying a pulley and having a flexible line passing around the pulley. The flexible line is connected between a tension device (e.g., a winch) and the payload. The method further includes activating the tension device to reel in the flexible line and accelerate the payload upwardly. |
| US11066180B2 |
Refuelling system
A refuelling system is disclosed having a fuel conduit, a variable-position valve for controlling a rate of flow of fuel leaving the conduit, and a controller. The controller is configured to receive from a sensor arrangement a measurement of an electrostatic condition in a fuel tank being fuelled by the system. The controller is configured to control the variable-position valve to control the rate of flow of fuel based at least in part on the measurement received from the sensor arrangement. |
| US11066179B2 |
Fire seal assembly for nacelle doors
A seal assembly may comprise a door configured to translate relative to a static structure. A seal may be disposed in a seal envelope defined, at least, partially by the static structure and the door. The seal may be configured to compress in a direction generally perpendicular to a direction of motion of the door. |
| US11066176B2 |
Canopy support lane divider
An evacuation system may comprise a packboard, an evacuation slide configured to deploy from the packboard, and a lane divider attached to the evacuation slide, wherein a first end and a second end of the lane divider are detachably coupled to a center tube of the evacuation slide, wherein a connecting member is coupled to the center tube between the first end and the second end of the lane divider. The lane divider may be in fluid communication with the center tube. A detachable restraint may be disposed between first end and the center tube, the detachable restraint comprising a first portion coupled to the center tube and a second portion coupled to first end, wherein the first portion of the detachable restraint detachably couples to the second portion of the detachable restraint. |
| US11066169B2 |
Drone forklift
A UAV includes a fork lift system and a length component. The forklift system includes one or more elongated members extending at least partially in a horizontal direction. The forklift system also includes an extension mechanism configured to selectively retract and extend the one or more elongated members relative to an opposing surface. For example, the elongated members may include the tines of the fork or supporting member of the forklift system. The length component is configured to control the extension mechanism to adjust a distance between the opposing surface and the one or more elongated members to accommodate a payload. |
| US11066167B2 |
Method and apparatus used for biological control of agricultural pests
An apparatus for biological control of agricultural pests and for reducing damage to crops. The apparatus includes a container for holding biological organisms or material. The container also includes first and second ends and an opening formed at the first end for receiving the biological organisms. The apparatus has a dispensing port disposed at the second end for dispensing the biological organisms over a target location. The apparatus further includes an auger, driven by a motor and having a plurality of spiral like wire brushes, said auger mounted to and driven by a first motor; a spreader motor mount having a motor mount holding area for holding a second motor, the spreader motor mount having a motor mount connection area for connecting to the second end; and a spreader agitating device used for spreading the biological organisms or material over the target location. |
| US11066166B2 |
Release unit for drones
A unit that is mountable to an underside of drone to attach an attachment to the drone and then release the attachment after the drone is airborne. The unit is provide with a retractable bar that is controllable via a remote controller. In use, an attachment is suspended from the bar and once the drone becomes airborne, a user may retract the bar via remote control to drop the attachment previously suspended from the bar. |
| US11066164B1 |
Secure remote access to components of an unmanned aerial vehicle
Disclosed are various embodiments for providing secure remote access to various components of an unmanned aerial vehicle (UAV), for instance, during a flight of the UAV or when the UAV is at a predetermined location. A computing environment may configure an unmanned aerial vehicle to permit access to the unmanned aerial vehicle when presented with a digital certificate signed by a trusted certificate signing service. Further, the computing environment may authenticate a client device requesting access to the unmanned aerial vehicle to perform a configuration and generate a digital certificate signed by the trusted certificate signing service that enables encrypted communication between the client device and the unmanned aerial vehicle. |
| US11066156B2 |
Propeller units
An aerial vehicle includes one or more propeller units operable to provide thrust for takeoff or hover flight and one or more propulsion units operable to provide thrust for forward flight. At least one propeller unit includes a shaft coupled to a motor, and a first propeller blade and a second propeller blade that are both connected to the shaft. The second propeller blade is located substantially opposite the first propeller blade, and the second propeller blade has a surface area substantially perpendicular to an axis of rotation that is greater than a corresponding surface area of the first propeller blade. While the aerial vehicle is in forward flight in a first direction and the motor is turned off, the first propeller blade and the second propeller blade are each configured to orient in a second direction that is substantially parallel to the first direction, such that the first propeller blade is oriented substantially upwind of the second propeller blade. |
| US11066154B2 |
Drive system for aircraft landing gear
A method of engaging a drive system with a rotating wheel of an aircraft landing gear is disclosed. A motor is operated to apply torque to a pinion so the pinion rotates. An engagement command is issued to an actuator at an engagement time, and the actuator operates the actuator in response to the engagement command to move the pinion from a neutral position to a contact position in which it contacts a rotating driven gear at an initial contact time, the rotating driven gear being mounted to a rotating wheel of an aircraft landing gear; then after the initial contact time operating the actuator to move the pinion further to a meshing position where the pinion meshes with the driven gear. A centre-to-centre distance between the pinion and the driven gear reduces as the pinion moves to the contact position and to the meshing position. |
| US11066152B2 |
Slotted entry gimbal
The present disclosure provides a slotted entry gimbal including an inner ring with a first side and a second side. The inner ring includes a first pin extending from the first side of the inner ring and a second pin extending from the second side of the inner ring. The slotted entry gimbal also includes an outer ring including a first side and a second side. The outer ring includes a first opening on the first side configured to receive the first pin and a second opening on the second side configured to receive the second pin. The outer ring includes a first slotted entry opening on the first side extending from a first edge of the outer ring to the first opening, and the outer ring includes a second slotted entry opening on the second side extending from a second edge of the outer ring to the second opening. |
| US11066149B2 |
Airflow-dependent deployable fences for aircraft wings
Airflow-dependent deployable fences for aircraft wings are described. An example apparatus includes a fence coupled to a wing of an aircraft. The fence is movable relative to the wing between a stowed position in which a panel of the fence extends along a skin of the wing, and a deployed position in which the panel extends at an upward angle away from the skin. The panel is configured to impede a spanwise airflow along the wing when the fence is in the deployed position. The fence is configured to move from the deployed position to the stowed position in response to an aerodynamic force exerted on the panel. |
| US11066148B2 |
Folding wing hinge, aircraft and method therefor
A folding wing hinge for a wing having a fixed wing portion and a folding wing portion, the folding wing hinge including a hinge pin including a hinge pin spline and having a first longitudinal axis, an input fitting coupled to one of the fixed wing portion and the folding wing portion, the input fitting including an input fitting spline and a second longitudinal axis, and a spline coupling member having a coupling spline configured to couple with the hinge pin spline and the input fitting spline so that the first longitudinal axis moves relative to the second longitudinal axis by a first predetermined amount of movement. |
| US11066147B2 |
Structured panel with integrated skin and sidewalls
A panel includes a core between and connected to a first skin and a second skin. The core includes a corrugated body, a first sidewall and a second sidewall. The corrugated body includes a plurality of corrugations configured from at least a plurality of baffles and a plurality of septums. Each of the corrugations includes a respective one of the baffles and a respective one of the septums. A first cavity extends laterally within the core from a first of the baffles to a first of the septums. The first cavity extends longitudinally within the core from the first sidewall to the second sidewall. The first cavity is fluidly coupled with a passage through a first portion of the first skin. The first portion of the first skin, the first sidewall and the second sidewall are collectively at least partially formed by a ply of material. |
| US11066144B1 |
Tiller control for boats
A tiller control for boats comprising a brake that holds a control line in a static position. In turn, the control line holds the tiller and rudder of the boat in a static position. The amount of pressure applied to the control line by the brake is adjustable. Pressure applied to the control line by the brake may be adjusted so that the tiller and rudder are held in a generally static position, but the tiller control can be manually overridden. |
| US11066143B2 |
Cooling system for electric propulsion system of watercraft
A cooling system for a boat includes at least one cooler located inside a hull of the boat and closed to the exterior of the hull. The cooler is configured for the exchange of thermal energy between a flow of coolant in the at least one cooler and a fluid flow outside of the hull via a hull wall positioned between the flow of coolant and the fluid flow. One or more coolant passages extend from the at least one cooler defining at least one coolant loop. The one or more coolant passages are configured to deliver the flow of coolant from the at least one cooler to one or more components located along the at least one coolant loop to cool the one or more components, and return the flow of coolant to the at least one cooler. |
| US11066140B1 |
Outboard motors having resilient mounting apparatuses
An outboard motor has a powerhead; a driveshaft housing located below the powerhead; a steering arm extending forwardly from the driveshaft housing; a steering tube extending downwardly from the steering arm; an upper mounting device that resiliently mounts the steering arm to the driveshaft housing; and a lower mounting device comprising a yoke that laterally extends from the steering tube. The yoke is clamped to the steering tube and contains port and starboard mounts that resiliently couple the steering tube to the driveshaft housing. |
| US11066139B2 |
Determining the partial pressure of a gas in a pressure vessel
There is disclosed a method and system for determining the partial pressure of at least one gas in a mixture of gasses contained in a pressure vessel, in particular a pressure vessel in the form of a life support pressure chamber/decompression chamber, or a diving gas storage cylinder. The method comprises the steps of: coupling a gas analysis sensor (14) to a pressure vessel (10); directing a portion of the mixture of gasses in the pressure vessel to the sensor for analysis; reducing the pressure of the portion of the mixture which is to be analysed by the sensor to a level which is below the pressure in the vessel but above local atmospheric pressure; operating the sensor to measure the partial pressure of the at least one gas at the reduced pressure level; and using the partial pressure of the at least one gas, measured at the reduced pressure level, to determine the actual partial pressure of said gas in the mixture contained in the vessel. |
| US11066134B1 |
Inflatable ride-on water toy
An inflatable ride-on water toy comprising a stylized body that is connected to a separately inflated safety ring using a variety of configurations. |
| US11066133B1 |
Gas supply marine vessel
A gas supply marine vessel and a refueling facility are described. The gas supply marine vessel includes a hull with an upper deck having an elongated cargo cavity formed therein. Gas interface modules are disposed in the cavity and extend between hull sides, each module having a plurality of fuel vessel docking stations. A plurality of stacked fuel container assemblies are fluidically coupled to the docking stations. A gantry, is movable along the length of the cavity, straddles the cargo cavity between hull sides. An articulating crane is mounted on the gantry and it utilized to move fuel container assemblies to a fuel container depression formed in the deck of a floating refueling facility. The floating refueling facility includes a concave side to facilitate mooring adjacent a shoreline, the concave side forming angled extensions at corners of the deck with a linkspan extending from each of the angled extensions. |
| US11066131B2 |
Mooring rope device of floating offshore structure for avoiding ship collision, method for operating same, and method for installing same
A floating offshore mooring chain apparatus for preventing collision with a ship is proposed. The mooring chain apparatus includes a buoyant body floating on the water surface to transfer resources to a transport ship, a plurality of mooring chains fixed to the seabed to locate the buoyant body in position on the water surface, and a plurality of spider buoys disposed to a lower portion of the buoyant body such that the mooring chains laterally penetrate through the spider buoys, respectively, and extend toward the seabed in different directions, so that the mooring chains are moved by a rotating force along the extension directions thereof to displace the buoyant body. |
| US11066124B2 |
Bicycle pedaling torque sensing systems, methods, and devices
A device for sensing a bicycle pedaling torque input includes: a housing; a bearing defining a rotational axis; a bearing support member that positions the bearing with respect to the housing, the bearing support member including one or more beams; an output member configured to be coupled to a chain ring, the output member being coupled to an inner race of the bearing to enable the output member to rotate with respect to the housing about the rotational axis; a spindle configured to be coupled to a bicycle pedal crank, the spindle functionally coupled to the output member to enable a rider pedaling force applied to the spindle to cause rotation of the output member; and one or more strain gauges, each of the one or more strain gauges being coupled a beam of the bearing support member. |
| US11066118B2 |
Bicycle seatpost system
A bicycle seatpost system is basically provided with a height adjustable seatpost and an electronic controller. The height adjustable seatpost includes an electric actuator. The electronic controller is configured to control the electric actuator to change a height of the height adjustable seatpost in accordance with detected information about a change of orientation of a bicycle relative to a ground. |
| US11066110B2 |
Fastening structure for vehicle
In a suspension member having a closed cross section, insertion holes are respectively formed in an upper member and a lower member that are two opposing walls. A collar includes a cylindrical portion and a flange. The cylindrical portion is inserted through the insertion holes. On the upper member side, the cylindrical portion and the upper member are welded together, forming a weld bead. On the lower member side, the outer circumferential edge of the flange and the lower member are welded, forming a weld bead. The welding is applied so that the length of the welding line on the lower member side is longer. |
| US11066106B2 |
Versatile platform
Provided is a versatile platform having high versatility without increasing its weight. A versatile platform is used for a transport vehicle for crops, a security robot, or the like. The versatile platform includes a first axle, a second axle, a pair of first wheels and, a pair of second wheels and, motors and for driving the four wheels, a first steering portion for steering the first wheels, a second steering portion for steering the second wheels, and a battery support portion. A vehicle body frame integrally joins the first axle and the second axle and supports a work unit for performing operation. The vehicle body frame includes horizontal bar members and vertical bar members and is formed into a frame shape. The whole upper surface of the vehicle body frame is exposed to the outside. |
| US11066104B2 |
Vehicle body structure and vehicle including the same
A vehicle body structure includes a battery mounting portion arranged on a floor of a vehicle and having a battery disposed thereon; a first cross member arranged in a front side of the battery mounting portion and reinforcing the floor; a second cross member arranged in a rear side of the battery mounting portion and reinforcing the floor; first and second extension members extending in a longitudinal direction so as to connect the first and second cross members while being spaced apart from each other in a transverse direction, and reinforcing a lower portion of the battery mounting portion; and a coupling structure coupled to the first and second cross members in a state of coupling the battery. |
| US11066100B2 |
Trailer backup assist curvature control
A vehicle has a trailer backup steering input apparatus, a trailer backup assist control module coupled to the a trailer backup steering input apparatus, and an electric power assist steering system coupled to the trailer backup assist control module and. The trailer backup steering input apparatus is configured for outputting a trailer path curvature signal approximating a desired curvature for a path of travel of a trailer towably coupled to the vehicle. The trailer backup assist control module is configured for determining vehicle steering information as a function of the trailer path curvature signal. The electric power assist steering system is configured for controlling steering of steered wheels of the vehicle as a function of the vehicle steering information. |
| US11066098B2 |
Vehicle disturbance detection apparatus
A vehicle disturbance detection apparatus includes an electronic control unit. The electronic control unit determines whether a disturbance occurs in a vehicle based on detection signals from a sensor device. The disturbance is a lateral external force that causes the vehicle to veer in a direction different from a direction expected by a driver. The electronic control unit determines that the disturbance occurs in the vehicle when a disturbance determination condition is established in a relationship between a calculated yaw rate and an actual yaw rate. The disturbance determination condition includes a cant traveling exclusion condition that is not established when the vehicle veers by traveling along a cant road but is established when the vehicle veers by receiving a crosswind. |
| US11066095B2 |
Controller for steering system and method for controlling steering system
A controller includes a control circuit configured to calculate a target corresponding steered angle that is a target value of a corresponding steered angle based on the transmission ratio associated with the vehicle speed. The corresponding steered angle is a rotation angle of a rotation shaft, which is convertible to the steered angle whose magnitude is changed relative to a value indicating the steering angle. The control circuit is configured to control the actuation of the motor so that an actual corresponding steered angle is a final target corresponding steered angle that is based on the target corresponding steered angle. The control circuit is configured to calculate the target corresponding steered angle by adjusting the transmission ratio based on a value indicating acceleration or deceleration of a vehicle. |
| US11066092B2 |
Steering wheel
A steering wheel includes a decorative component and a surface skin on a surface of the rim. The decorative component is formed into a band and a leading-end portion of the decorative component has a tapered form in which an inner edge curves towards an outer circumference of the rim and serves as a curving edge. The surface skin includes a curved-side section adjoining the curving edge and a non-curved-side section adjoining a non-curving edge of the leading-end portion. The curved-side section includes a main body that includes a curving portion which corresponds to the curving edge of the leading-end portion in shape, and an extended portion that extends beyond an apex of the leading-end portion and extends towards the non-curving edge of the leading-end portion of the decorative component. A region of the extended portion beyond the apex is joined to a leading edge of the non-curved-side section. |
| US11066091B2 |
Operating apparatus comprising rocker element for operating at least one electrical appliance, motor vehicle component comprising an operating apparatus, motor vehicle and method for operating an operating apparatus
An operating apparatus for operating at least one electrical appliance in a motor vehicle may include an operating element, a rocker that may actuate a switching element using a rocker movement initiated by an actuation of the operating element, at least one connector between the operating element and the rocker, the at least one connector being a vertical pin connector, and a circuit board which may include a first side and a second side. The first side may include a switching element that switches when the operating element is actuated. The circuit board may be arranged between the operating element and the switching element so that the first side faces away from the operating element and the second side, lying opposite the first side, faces the operating element. |
| US11066090B2 |
Stabilizer wheel assembly and methods of use
Included is a stabilizer wheel assembly that may assist in stabilizing a medical device during a medical procedure. A medical device may comprise a body; and a plurality of stabilizer wheel assemblies coupled to the body, wherein the stabilizer wheel assemblies each comprise a motor assembly and a stabilization leg, wherein the motor assembly is configured to drive the stabilization leg onto a contact surface to stabilize the body. |
| US11066087B2 |
Maintenance assistance system and maintenance assistance method for railroad ground equipment
An object is to improve the accuracy of prediction of deterioration of railroad ground equipment. Provided is a maintenance assistance system for railroad ground equipment, comprising: an environmental-information storage part storing environmental information containing information on weather observed at a plurality of geographical points and on geographical conditions at the geographical points; and an environmental-load estimation part holding a relational formula indicating the relationship between aged deterioration of railroad ground equipment and the environmental information, and configured to, upon specification of railroad ground equipment for which to execute deterioration prediction, acquire the environmental information which is recorded at a point near the installed position of the railroad ground equipment, during the target period of the deterioration prediction, and predict the degree of aged deterioration of the railroad ground equipment by using the acquired environmental information and the relational formula. |
| US11066084B2 |
Railcar air-conditioning duct
Provided is a railway vehicle air-conditioning duct that is capable of achieving a more uniform in-cabin temperature distribution through more appropriate volume distribution of conditioned air. A railway vehicle air-conditioning duct that supplies conditioned air generated by an air conditioner into a cabin and that extends in a vehicle length direction at a vehicle ceiling part has: a main duct; a chamber duct; a branch duct; and a guide part. The guide part is lower in height than the main duct, extends to a branch duct from the main duct or a partition wall in the main duct in a vehicle width direction, and supplies to the branch duct a portion of the conditioned air supplied to the main duct. |
| US11066080B2 |
Vehicle control device and electronic control system
Implemented is a highly reliable vehicle control device capable of performing control transition safely to a degeneration control microcomputer even if an operation abnormality occurs in a control microcomputer in a vehicle control device.Provided are: a control microcomputer 11b that outputs a control command to an actuator control device; and a degeneration control microcomputer 12b for control transition when an abnormality is detected in the control microcomputer 111b. When transitioning to the degeneration control microcomputer 12b when detecting the abnormality in the control microcomputer 11b, the control microcomputer 12b is notified of the abnormality of the control microcomputer 11b, and the control microcomputer 11b is reset after the required transition period of the degeneration control microcomputer 12b has elapsed and the degeneration control has started. As a result, a control blank period is eliminated. |
| US11066079B2 |
Expanding cruise control enable criteria
A vehicle, system for operating the vehicle and method of activating a control system is disclosed. The system includes a sensor for detecting lane markings of a driving lane, a road wheel angle sensor configured to measure a road wheel angle of the vehicle, and a processor. The processor is configured to determine a distance of the vehicle from a central line of a driving lane form the detected lane markings, adjust an angular threshold for activation of the control system of the vehicle based on the determined distance, and activate the control system when the road wheel angle is within the angular threshold. |
| US11066078B2 |
Vehicle position attitude calculation apparatus and vehicle position attitude calculation program
A vehicle position attitude calculation apparatus includes: a road structure recognition portion that acquires information, calculate a road structure shape, calculate a relative road structure lateral position, and calculate a relative road structure yaw angle; a storage portion that stores the road structure shape, the relative road structure lateral position, and the relative road structure yaw angle, an autonomous navigation portion that calculates a relative trajectory; a virtual road structure recognition portion that calculates a virtual relative road structure lateral position and a virtual relative road structure yaw angle; and an output switching portion that outputs the relative road structure lateral position and the relative road structure yaw angle, while the road structure recognition portion can recognize the road structure, and output the virtual relative road structure lateral position and the virtual relative road structure yaw angle, while the road structure recognition portion cannot recognize the road structure. |
| US11066072B2 |
Apparatus and method for assisting driving of host vehicle
The present disclosure provides a driving assist apparatus including a host vehicle stop determiner for determining the stop state of a host vehicle, a preceding vehicle stop determiner for determining the stop state of the preceding vehicle, a preceding vehicle start determiner for determining the start of the preceding vehicle after the stop of the preceding vehicle based on a speed change information of the preceding vehicle and a distance change information between the host vehicle and the preceding vehicle, and a start notifier for notifying the start of the preceding vehicle after the stop to a driver of the host vehicle. |
| US11066070B2 |
Apparatus and method for controlling speed in cooperative adaptive cruise control system
An apparatus and method for controlling a vehicle speed based on information about forward vehicles that travel in the same lane may be acquired using Vehicle to Everything (V2X) communications in a cooperative adaptive cruise control (CACC) system. The CACC system includes a communication unit receiving vehicle information from neighboring vehicles using V2V communications; an information collection unit collecting vehicle information of the neighboring vehicles and the subject vehicle using sensors; and a control unit determining a forward vehicle and a far-forward vehicle using the sensors, selecting first and second target vehicles for being followed by the subject vehicle based on the vehicle information of the forward vehicle and the far-forward vehicle and the vehicle information of the neighboring vehicles, and controlling the driving speed of the subject vehicle based on speed information of the first and second target vehicles. |
| US11066069B2 |
Extra-freedom stitch method for reference line smoothing
In one embodiment, a method for generating a reference line for operating an autonomous driving vehicle includes controlling an autonomous driving vehicle to move along a road according to a first reference line, the first reference line having a first set of constraints, and while the autonomous driving vehicle is moving along the road according to the first reference line: truncating the first reference line by removing an end section of the first reference line to generate a truncated first reference line including an end reference point, obtaining a second set of constraints for the end reference point, obtaining a second reference line to be used by the autonomous driving vehicle, the second reference line having the first set of constraints, and connecting the second reference line to the end reference point of the truncated reference line to allow the autonomous driving vehicle to move along the road. |
| US11066065B2 |
Methods and system for repositioning a vehicle
Systems and methods for operating a vehicle that includes a starter motor are described. In one example, the starter motor may engage a flywheel of an engine and rotate the engine without starting the engine in response to a request to move the vehicle without starting the engine. The starter motor may provide the propulsive force to move the vehicle a short distance. |
| US11066060B2 |
B6+3 bridge for motor control and series pass regulation in an integrated starter generator application
This disclosure describes a control circuit to manage the energy flow for an integrated motor generator (IMG), such as an integrated starter generator (ISG) system. The circuit regulates the output voltage of the IMG when the IMG operates in generator mode. The circuit includes an additional switch for each phase connected in anti-series with the half-bridge circuit for the phase, e.g., the drain of the additional switch connects to the drain of the high-side switch. When the ISG is in generator mode, the additional switches are controlled, e.g., to charge the battery at a constant voltage and current throughout the speed range of the ISG (i.e. high rpm and low rpm). In generator mode, the high-side switches may be turned off, which configures the high-side switches to act as a diode and block battery discharge for low rpm operation when the phase voltages are lower. |
| US11066058B2 |
Method of controlling vacuum pressure for vehicle braking
A method of controlling vacuum pressure for vehicle braking may include checking whether a vehicle is idle or enters a deceleration state, comparing an engine vacuum pressure and a booster vacuum pressure of the vehicle with a preset reference value, checking whether a valve control system of the vehicle is operable when the engine vacuum pressure and the booster vacuum pressure are lower less than the preset reference value, controlling the valve control system when the valve control system is operable; and controlling an air conditioner (A/C) or an alternator of the vehicle when the valve control system is inoperable. |
| US11066055B2 |
Braking system for a motor vehicle
A braking system for a motor vehicle for actuating hydraulically actuatable wheel brakes comprises a first and a second electrically controllable pressure source for providing a brake pressure for actuating the wheel brakes. A first electric energy supply unit and a second electric energy supply unit that is independent of the first electric energy supply unit are provided. An electrically controllable pressure modulation device for setting brake pressures that are individual to each of the wheel brakes has at least one electrically actuatable inlet valve for each wheel brake. The first pressure source can be supplied with electric energy by the first energy supply unit, the second pressure source can be supplied with electric energy by the second energy supply unit, and the pressure modulation device can be supplied with electric energy by the first energy supply unit and by the second energy supply unit. |
| US11066051B2 |
Wheel sensors within vehicular brake assemblies
A drum braking system having a spindle and backing plate affixed thereto. The system includes a drum rotating on the spindle. The drum has an inside surface with integral notches that are machined or cast into the drum. When the brakes are applied, brake shoes are actuated to contact the inside surface to create drag between the drum and the spindle. A sensor is fixed with respect to the spindle or backing plate that detects the notches when the drum rotates about the spindle. A portion of the inside surface with the integral notches is shared with the brake shoes so that applying the brakes prevents buildup that could contact the sensor. The sensor is positioned radially to reduce the effect of drum endplay on detecting of the notches. |
| US11066046B2 |
Authentication concealment and alignment systems
An authentication apparatus configured to identify a user comprises a scanning apparatus configured to capture identifying information of the user and a feedback apparatus configured to communicate alignment information for the scanning apparatus to a user. A controller is in communication with the scanning apparatus and the alignment apparatus. The controller is configured to activate the feedback apparatus to reveal the alignment information identifying an alignment with the scanning apparatus. The controller is further configured to capture the identifying information of the user and identify the user in response to the identifying information. |
| US11066041B2 |
Belt retractor
The invention describes a belt retractor for a vehicle seat belt comprising a belt reel (12) supported for rotation in a frame, a sensor (16) for vehicle-sensitive blocking of the belt reel (12) and a mechanism (17) for disabling the sensor (16). Via a gear (18) supported for rotation on the frame and a cam follower (22) the belt reel (12) acts on the mechanism (17) for disabling the sensor (16) and can adjust the same. |
| US11066034B2 |
Airbag module for protecting the head
A head protection airbag module comprising a tubular inflator, a holder for the inflator and an airbag which is in fluid communication with the inflator and is folded to form a package, characterized by a guide element for the airbag which is arranged on the holder and includes a guide tongue extending into the airbag package. |
| US11066030B2 |
Method and control device for controlling at least one occupant protection device for a vehicle during a collision, and system for occupant protection for a vehicle
A method for controlling at least one occupant protection device for a vehicle in the case of a collision, including determining input data which represent an ignition time of an airbag of the vehicle, an angular frequency of the collision, an available displacement path of a vehicle occupant relative to the vehicle, a mass of the vehicle occupant of the vehicle, a distance of the vehicle occupant from the airbag, and an inflation time duration of the airbag; ascertaining a restraint force using the input data. The restraint force represents a force that can be provided by the at least one occupant protection device and that is suitable to minimize an occupant energy of the vehicle occupant up until the end of the collision; and providing a control signal for controlling the at least one occupant protection device, the control signal being produced using the restraint force. |
| US11066029B2 |
Method for activating at least one secondary function of an occupant protection system of a vehicle
A method, a device and a computer program for activating a secondary function of an occupant protection system, a vertical acceleration and a lateral acceleration being detected and evaluated and an instantaneous position of the vehicle being determined based on the vertical acceleration and the first lateral acceleration. In the process, a lifting-off of the vehicle and/or an impact of the vehicle on its wheels is detected. A secondary function is activated if an impact of the vehicle on its roof and/or if an impact of the vehicle on one side or an impact of the vehicle on its wheels is detected. |
| US11066024B2 |
Grommet assembly
A grommet assembly includes an inner member having a body portion to be inserted into a mounting hole of a panel, and a panel engagement portion formed on the body portion and to be engaged with an opening edge of the mounting hole, a grommet to be mounted to a rear side of the inner member, the grommet including an annular panel contact portion having a seal part to contact a portion of the panel surrounding the mounting hole, and a tubular wire housing portion connected to the panel contact portion and to cover an electric wire such that the electric wire bends with respect to a center axis of the mounting hole and a protruding member to protrude from a rear side of the body portion, the protruding member including a pressing support portion extending along an inner surface of a rear wall of the wire housing portion. |
| US11066015B2 |
Adjustable mirror assembly for a work machine
In accordance with one aspect of the present disclosure an adjustable mirror assembly for a work machine is disclosed. The adjustable mirror assembly includes a support bracket adapted to be attached to the work machine and an intermediate bracket. The intermediate bracket interfaces with a back surface of a mirror and with the support bracket. The adjustable mirror assembly includes a first linear actuator for rotating the mirror about a pitch axis. The first linear actuator to rotate the mirror about a pitch axis attaches to the support bracket and to the intermediate bracket. A second linear actuator to rotate the mirror about a yaw axis is attached to a point fixed to the intermediate bracket and to the back surface of the mirror. |
| US11066012B2 |
Lighting device
Provided is a lighting device capable of minimizing damage of a joint portion between an operation switch and a substrate or the substrate itself due to a force when the operation switch is operated and improving assemblability. The lighting device includes a housing installed in a vehicle, a substrate fixed to the housing, a cover member which is fixed to the housing and presses down the substrate, a light emitting element installed on the substrate, an operation switch which is installed on the substrate and switches the light emitting element on/off by being operated in directions of coming into contact with and moving away from the substrate, and a movement restricting portion which is formed in the housing, engages with a part of the operation switch and restricts movement of the operation switch toward the substrate side. |
| US11066010B2 |
Apparatus for providing notification of opening or closing of scissor doors for vehicle
An apparatus for providing a notification of opening or closing of scissor doors for a vehicle is intended to indicate an opening or closing state of the scissor doors installed in the vehicle. The apparatus includes: a first indicator unit installed in a left section of a rear side of the vehicle to indicate an opening state of a left scissor door; a second indicator unit installed in a right section of the rear side of the vehicle to indicate an opening state of a right scissor door; a motor for activating the first indicator unit and the second indicator unit; and a clutch unit to selectively activate the first indicator unit and the second indicator unit. |
| US11066009B2 |
Vehicular illumination device, vehicle system, and vehicle
A vehicle illumination device which is provided in a vehicle capable of travelling in an automatic driving mode includes an illumination unit configured to display stop warning information forewarning stop of the vehicle toward a front of the vehicle, and an illumination controller configured to control the illumination unit such that the stop warning information is displayed toward the front of the vehicle. |
| US11066008B2 |
Lighting through chrome plating or chrome-like surface treatments
An illuminable vehicle component and a method for illuminating a vehicle component includes a vehicle component including an A-surface, a photoluminescent or electroluminescent light source covering the A-surface, a pigmented layer coving the photoluminescent or electroluminescent light source, and an optional optically clear top coat covering the pigmented layer. When the photoluminescent or electroluminescent light source is not activated and is not emitting light, the pigmented layer has an opaque appearance. When the photoluminescent or electroluminescent light source is activated to emit light, light emitted from the photoluminescent or electroluminescent light source is transmitted through the pigmented layer and the optional optically clear top coat such that the illuminable vehicle component has an illuminated appearance and the component is illuminated. |
| US11066004B2 |
Equipment mounting system
An equipment mounting system may include a quick mount track having a backing plate with a center slot, a first outer slot, and a second outer slot, the first outer slot and the second outer slot comprise a plurality of diamond contour target regions, and a plurality of locking pin apertures along the center slot in the backing plate, the locking pin apertures are in horizontal alignment with the plurality of diamond contoured target regions. The equipment mounting system also may include a mount removably coupled to the quick mount track wherein the plurality of diamond contour target regions allow for a round head of a t-shaped stud of the mount to engage the first outer slot and the second outer slot at an angle to the backing plate. |
| US11066003B1 |
Appliance lockdown for expandable shelter
A system including a frame and a pair wheel of assemblies to engage with one or more tracks of a structure. The pair of wheel assemblies include a first hub assembly, having a first wheel and a first attachment mechanism to engage with the one or more tracks of the structure, and a second hub assembly having a second wheel and a second attachment mechanism to engage with the one or more tracks of the structure. The system further includes an elongated rod coupling the first hub assembly to the second hub assembly, where a movement of the elongated rod causes the first attachment mechanism and the second attachment mechanism to engage with the one or more tracks of the structure. |
| US11065994B2 |
Quick-attachment assembly for attaching a seatback frame to a vehicle frame and selected detachment therefrom
A vehicle seat attachment includes a riser bracket of a vehicle frame. A pin is biased through the riser bracket to a securing position. A seat bracket has an angled channel that extends to a securing aperture, wherein slidable engagement of the angled channel with the pin is configured to bias the pin away from the securing position until the pin reaches the securing aperture wherein the pin returns to the securing position. |
| US11065990B2 |
Vehicle body structure
A vehicle body structure of a four-wheeled vehicle includes a pair of side members (8) extending in a fore and aft direction along either side of the vehicle body, a plurality of cross members (41, 42, 43) extending laterally between the side members, and a floor panel (58) attached to an upper side of the cross members. One of the cross members (42) passes through an intersection point of diagonal lines of a rectangular formation of supporting points of the four wheels, and at least one of the seat mounts (72) is positioned on the one cross member. |
| US11065988B1 |
Easy entry latch for vehicle seat
An occupant support includes a vehicle seat mounted to a foundation frame for sliding the vehicle seat longitudinally in a vehicle. The vehicle seat is movable from a slid-back configuration to a forward-seating configuration and may be changed from a horizontal-use configuration to a tilted configuration for easy entry into or exit from a rear row of the vehicle. The vehicle seat may be locked in the tilted configuration. |
| US11065987B2 |
Seat slide device for vehicle
In the present invention, in a bottom portion 4a of a lower rail 4, a foreign matter interference portion 27 protruding upward and having a substantially arc-circular shape in a side view is formed by being cut and raised in a middle part in a rail width direction more on a front side than a bolt hole 26 for a mounting bolt for fixing the rear end portion of the lower rail 4 to a vehicle body. Rear-side stoppers 29 and long hole portions 31 shared with the rear-side stoppers 29 are formed on both sides of the foreign matter interference portion 27. The foreign matter interference portion 27 is separated into a front-side tongue piece 27a and a rear-side tongue piece 27b by a slit 32. |
| US11065986B2 |
Longitudinal adjuster for a vehicle seat, and vehicle seat
A longitudinal adjuster for a vehicle seat having at least one pair of rails. The at least one pair of rails may be formed from a first seat rail for connecting to a seat structure, and from a second seat rail for connecting to a vehicle structure. The seat rails of the pair of rails are displaceable in the longitudinal direction relative to each other and mutually engage around each other to form an inner channel. A securing profile, which is fastened to the first seat rail, is arranged in the inner channel. A rack which is fixed relative to the second seat rail is arranged in the inner channel. The securing profile and the rack are normally spaced apart from each other and enter into engagement with each other in a form-fitting manner in reaction to a predetermined action of force. |
| US11065981B2 |
Air-conditioning apparatus for electric vehicle and method of controlling same
An air-conditioning apparatus for an electric vehicle and a method of controlling the same, may include a heat exchanger performing heat exchange between a first fluid and a second fluid while the first fluid and the second fluid flow separately from each other therethrough; a heat source connected to the heat exchanger through a line through which the second fluid flows to allow the second fluid to circulate between the heat exchanger and the heat source, and heating or cooling the second fluid; a circulator imparting a circulation force to the second fluid such that the second fluid circulates between the heat exchanger and the heat source; and a controller determining a required flow rate of the second fluid by use of a flow rate of the first fluid flowing through the heat exchanger and controlling the circulator on the basis of the required flow rate of the second fluid. |
| US11065975B2 |
Method for electrically charging an energy store by switching between two configurations
A method for electrically charging an energy store. The method includes the following steps: starting an electrical charging process for the energy store in a first configuration; interrupting the charging process, changing the configuration of the energy store from the first configuration to a second configuration, and resuming the charging process in the second configuration. The energy store in the first configuration is designed to be charged with a higher electrical voltage than in the second configuration. |
| US11065974B2 |
Control system for autonomous vehicle
A vehicle control system for an autonomous vehicle configured to charge a battery by an external power source during propulsion while preventing a deterioration of the battery. A controller detects a charging zone where the electric storage device can be charged by the external power source, and restricts at least any one of a charging of the electric storage device and a discharging of electricity from the electric storage device so as to limit a load factor of the electric storage device to be smaller than a predetermined limit value when the vehicle passes through the charging zone. |
| US11065971B2 |
Charging connection module for a vehicle
A charging connection module for a vehicle includes a charging socket for electrical contacting with an external electricity source and a pot unit which constitutes a mounting for the charging socket and which is fastenable to an outer panel of the vehicle. The charging socket is integrated into the pot unit in an injection molded manner. |
| US11065970B2 |
Control device of vehicle with overheat protection control
A control device of a vehicle includes a controller performing overheat protection control on parts, distinguish first, second, and third parts groups among the parts of the vehicle, set only the first and the third parts group as protection targets in a charging mode while the vehicle stops, set only the second and the third parts group as the protection targets when the vehicle is in a mode other than the charging mode while the vehicle is running, and not to perform the overheat protection control when the vehicle is in a mode other than the charging mode while the vehicle stops. |
| US11065969B2 |
Chargeability presenting method and chargeability presenting system
A method of managing a vehicle parking place system having a management system apparatus which communicates with an information terminal and a vehicle parking place through a network. The method includes outputting vehicle presence information indicating whether or not a vehicle is present in a charging space included in the vehicle parking place; outputting foreign-object information indicating whether or not a foreign object is present, other than the vehicle, in a wireless power-supply region in the charging space; and presenting, in the information terminal, chargeability information that is generated based on the vehicle presence information and the foreign-object information. |
| US11065967B2 |
Systems and methods for a modular battery system
A modular battery system for use with a material handling vehicle, the modular battery system comprises a battery assembly and a counterweight assembly. The battery assembly can include a power source and a battery base, and the counterweight assembly can include a counterweight base configured to slidably receive the battery base and be removably secured thereto. |
| US11065961B2 |
Electric circuit and diagnosis method
An electric circuit switches connection among a plurality of storage cell units including a first storage cell unit and a second storage cell unit, a load of the plurality of storage cell units, and a power supply supplying power to the plurality of storage cell units. The electric circuit includes: a first rectifier configured to rectify a current flowing between a first pole terminal of the power supply and a first pole terminal of the first storage cell unit with homopolarity as polarity of the first pole terminal of the power supply; a second rectifier configured to rectify a current being different from the current and flowing between the first pole terminal of the power supply and a first pole terminal of the second storage cell unit with homopolarity as the polarity of the first pole terminal of the power supply; and a connection switching device configured to connect the plurality of storage cell units in series between the first pole terminal of the first storage cell unit and the first pole terminal of the second storage cell unit and release the series connection of the plurality of storage cell units during a period in which the power supply supplies power to the plurality of storage cell units. |
| US11065956B2 |
Drive device for a motor vehicle
A drive device for a motor vehicle includes a drive machine and a transmission device having a triple planetary great set and having a first and second clutch, wherein the triple planetary gear set has a plurality of triple planet gears, wherein each triple planet gear includes a first gear, a second gear, and a third gear. The three gears of each triple planet gear are connected to each other for conjoint rotation and are jointly rotatably accommodated on a planet carrier, and the drive machine is connected to the triple planetary gear set by the first clutch and a first sun gear or by the second clutch and a second sun gear. |
| US11065951B2 |
Charge air shutter
A passive shutter mechanism (10; 20) for a cooling pack (2) in a vehicle (1) adapted to selectively close at least part of an airflow path into the cooling pack (2), wherein the shutter mechanism comprises at least one blocking member (11; 21) adapted to be displaced between an open position, wherein air may flow into the cooling pack (2), and a closed position, wherein air is prevented from flowing into at least part of the cooling pack (2), depending on the movement of the vehicle (1). A vehicle (1) comprising such a passive shutter mechanism, as well as a method of operating such a passive shutter mechanism is also disclosed. |
| US11065950B2 |
Transmission with a mode selection apparatus
A method of shifting ranges within a transmission is provided. The method of an embodiment includes determining an intention to change from a first mode to a second mode in the transmission, determining the first mode of the transmission, which includes a first range clutch in an engaged condition and a first synchronizer in a first engaged condition, determining the second mode of the transmission, which includes a second range clutch in an engaged condition and a second synchronizer in a first engaged condition, engaging the second synchronizer in the first engaged condition, disengaging the first range clutch, engaging the second range clutch, and disengaging the first synchronizer from the first engaged condition. |
| US11065938B2 |
Control device for cooling device
The present invention provides a control device capable of controlling a cooling device in response to temperature changes due to external factors. The present invention is a control device for controlling a cooling device for cooling an object to be cooled, said control device being characterized by comprising: a temperature change prediction information acquisition unit for acquiring temperature change prediction information, which is information concerning temperature changes of the object to be cooled; a temperature change prediction unit for predicting the temperature changes of the object to be cooled on the basis of the temperature change prediction information acquired by the temperature change prediction information acquisition unit; and a control unit for controlling the cooling device for cooling the object to be cooled, such control carried out on the basis of the prediction results according to the temperature change prediction unit. |
| US11065937B2 |
Heat system for an electric or hybrid vehicle
A heat system for an electric or hybrid vehicle may be operated in multiple operating modes. The heat system includes a cooling circuit having a cooling unit and a heating heat exchanger for heating the interior. The heating heat exchanger is parallel connected to the cooling unit, for forming a heating circuit. At least one heat source is arranged in the cooling circuit for heat output to the cooling circuit. The heat system may also include a refrigeration circuit for heat exchange with the cooling circuit by way of a capacitor, and an evaporator circuit, which can introduce heat to the refrigeration circuit by way of the evaporator. |
| US11065936B2 |
Vehicle thermal system architecture
A thermal energy management system for a vehicle supplies thermal energy to a passenger compartment of the vehicle. The thermal energy management system includes three thermal fluid loops. The first thermal fluid loop includes a coolant pump for circulating a coolant through at least a vehicle battery, a transmission oil cooler of the vehicle, and a chiller such that the coolant selectively transfers thermal energy from the vehicle battery, the transmission oil cooler, and the chiller. The second thermal fluid loop circulates oil through the transmission oil cooler. The third thermal fluid loop circulates a refrigerant through at least the chiller and at least one condenser such that the third thermal fluid loop transfers thermal energy to the passenger compartment. |
| US11065930B2 |
Method and apparatus for on-center steering and a fast response vehicle
Presented herein are systems and methods for controlling a response (e.g., a roll, a pitch) of a vehicle body to a driver input. In one aspect, a method for controlling the response of the vehicle body is presented, the method comprising receiving an input (e.g., a steering wheel input, a pedal input) from an operator of a vehicle and modifying an aspect (e.g., a roll angle, a pitch angle, a roll rate, a pitch rate) of the response of the vehicle body, the modified aspect having a value based, at least partially, on the input. In another aspect, a controlled vehicle is presented comprising a vehicle body and one or more actuators configured to apply a torque to the vehicle body, the torque having a direction and/or magnitude based, at least partially, on a driver input (e.g. steering command, braking command, and/or acceleration command). |
| US11065929B2 |
Low suspension arm strut coupling
A low suspension arm strut coupling is provided for a suspension of an off-road vehicle. The suspension comprises a lower suspension arm that is hingedly coupled between a chassis of the off-road vehicle and a spindle assembly that is coupled with a front wheel. An upper suspension arm is hingedly coupled between the chassis and the spindle assembly. A strut is coupled between the lower suspension arm and the chassis. A lower pivot couples the strut to the lower suspension, and an upper pivot couples the strut to the chassis. The upper and lower pivots provide a lower center of gravity of the off-road vehicle and a relatively smaller shock angle. The lower suspension arm is reinforced to withstand forces due to movement of the front wheel and operation of the strut in response to travel over terrain. |
| US11065923B2 |
Wheel unit, system for transmitting data from a wheel unit, and method for transmitting data from a wheel unit
A wheel unit for a system for transmitting data from the wheel unit to a receiver of a vehicle. The wheel unit is configured for mounting to a wheel of the vehicle, and the wheel unit includes the following: a memory for storing wheel type data related to the type of the wheel at which the wheel unit is mounted; a processor for processing the wheel type data stored in the memory; a transmitter for RF-transmitting data telegrams to a vehicle-mounted receiver. The processor determines an RF power value based on the stored wheel type data, and the transmitter transmits the data telegrams with an RF power based on the determined RF power value. |
| US11065922B2 |
Tire pressure measurement device, an integrated circuit, a printed circuit board, a method and a computer program for a vehicle to receive data
Embodiments provide a tire pressure measurement device that includes an electromechanical transducer configured to convert mechanical energy from tire deformation of a tire into electrical energy for powering the tire pressure measurement device; and an energy harvesting circuit configured to receive and store the electrical energy from the electromechanical transducer, where the energy harvesting circuit is further configured to supply the stored electrical energy to the tire pressure measurement device. |
| US11065916B2 |
Pneumatic vehicle tire
A pneumatic vehicle tire has a nominal tire cross-sectional height H of at most 110 mm, bead regions with bead cores, a radial carcass which runs around the bead cores in the bead regions axially on the inside to axially on the outside forming carcass turn-ups, and side wall regions, which each have a wing profile and a side wall profile. The wing profiles are the only rubber components extending in contact with the radial carcass in the radially outer region of the side wall region. The carcass turn-ups end at a radial height (h1), determined from a base line, of 15 mm to 65 mm. At least in a region between a radial height (h2) of 29% of the nominal side wall height and a radial height (h3) of at least 80% of the height H, the wing profiles are the only rubber components that extend outside the radial carcass. |
| US11065914B2 |
Rubber-covered textile cords, tires containing same, and related methods
The present disclosure is directed to textile cords covered with a rubber composition of specified composition, tires having at least one component comprising the rubber-covered textile cords, and related methods for increasing aged cord coverage of rubber-covered textile cords and for preparing the rubber-covered textile cords. The rubber composition of specified composition includes silica filler in an amount of up to 20 phr and silane coupling agent in an amount of up to 5 phr. |
| US11065913B2 |
Formfitting securing device for a roller
A formfitting securing device for a roller has a rotation blocking engagement part which is biased into an engagement position by means of a first spring. The first spring exerts a bias onto the rotation-blocking engagement part both in the engaged position as well as in the nonengaged position, and a bias is achieved in the non-engaged position by acting on the rotation-blocking engagement part by means of a second spring. |
| US11065908B2 |
Extendable hand-held dry-erase sign
An extendable dry-erase board with a telescoping hand-held support extension handle pivotally-connected at one end to an accordion-folding dry erase board. The device can be easily transported by those traveling via bus, bicycle, walking, etc. to any sporting event, concert, or public demonstration and deployed instantly on-site, the dry-erase board being unfolded into a large prominent sign whereupon a message can be inscribed on the board, erased and rewritten as needed. |
| US11065904B2 |
Image forming system and image forming method
An image forming apparatus includes a processing tray, a post-processing controller, and a detection sensor. The processing tray is configured to support a sheet or a sheet bundle on which a post-processing is to be executed. The post-processing controller is configured to execute the post-processing on the sheet positioned on the processing tray. The detection sensor is configured to detect an object in a predetermined detection range including a space above the processing tray. The post-processing controller stops execution of the post-processing when the detection sensor detects the object at a determination timing other than a timing at which passage of the sheet or the sheet bundle through the detection range is estimated. |
| US11065900B2 |
Transfer of latex-containing ink compositions
Provided in one example herein is a method of printing. The method includes disposing onto a transfer paper an ink composition to form thereon an image, the ink composition including pigments and latex particulates. The method includes transferring the image from the imaged transfer paper onto a substrate comprising fabric by a lamination process. The lamination process includes: laminating together the substrate, the imaged transfer paper, and a release paper, whereby the image is transferred from the transfer paper onto the substrate. |
| US11065899B1 |
Methods, apparatuses, and systems for batch print voiding
Various methods and systems for a printer having verifiers are disclosed herein. Such methods provide for voiding a printed media in a batch printing run. The methods further correspond to identifying the printed media that is printed as part of the batch printing run as a failed media in an instance an assigned grade fails to satisfy a predetermined threshold, marking the printed media as a failed printed media, determining one or more subsequently printed media that were printed after the failed printed media, and reprinting the printed failed media in a next available media after the one or more subsequently printed media. |
| US11065895B2 |
Liquid discharge device and liquid discharge apparatus
A liquid discharge device includes a liquid discharge head to discharge a liquid, a head holder to hold the liquid discharge head, a sub-carriage to hold the head holder, a carriage to hold the sub-carriage and move in a main scanning direction, an adjuster supported by the sub-carriage, and a guide to guide the sub-carriage to be movable in a vertical direction. The carriage includes a reference shaft extending in the main scanning direction, the reference shaft supports the sub-carriage via the adjuster and positions the sub-carriage in the vertical direction, the adjuster adjusts an inclination of the sub-carriage with respect to the reference shaft, the sub-carriage includes a sub-reference shaft extending in parallel with the reference shaft, and the guide allows the sub-reference shaft to move in the vertical direction while restricting a movement of the sub-reference shaft in a sub-scanning direction perpendicular to the main scanning direction. |
| US11065894B2 |
Engageable fluid interface members and connectors
In some examples, a fluid ejection assembly is removably mountable in a system, and includes a fluid ejection device, and a removable frame on which the fluid ejection device is mounted. The removable frame includes a plurality of fluid interface members that share a common design to releasably engage with a plurality of fluid interface connectors together as the removable frame is brought into engagement with a support structure in the system and on which the plurality of fluid interface connectors are mounted. Engagement of a first fluid interface member with a first fluid interface connector establishes a gas path through the first fluid interface member and the first fluid interface connector, and engagement of a second fluid interface member with a second fluid interface connector establishes a liquid path through the second fluid interface member and the second fluid interface connector, the liquid path to deliver a liquid to the fluid ejection device. |
| US11065892B2 |
Printing apparatus and conveyance apparatus
To provide a printing apparatus and a conveyance apparatus that are capable of preventing a cut position to be cut by a cutting unit from deviating, in a printing apparatus in which printing is performed by a printing unit on a printing medium that is conveyed by a conveyance unit and the printing medium is cut by a cutting unit while being conveyed by the conveyance unit and a conveying force apply unit, the sconveying force apply unit is arranged on an outer side relative to the cutting unit and configured to apply a conveying force to the printing medium in a direction outward in a width direction from an upstream to a downstream in a conveyance direction. |
| US11065889B2 |
Digital binder printing
A method and equipment to form a digital image on a surface by applying a powder layer including colour pigments on the surfaces, bonding a part of the powder and removing the non-bonded powder from the surface. |
| US11065883B2 |
Cross-die recirculation channels and chamber recirculation channels
A die may, in an example, include at least one cross-die recirculation channel formed into the die to recirculate an amount of printing fluid therethrough, the cross-die recirculation channel including a first-sized inlet port and a first-sized outlet port formed on a first side of the die, at least one chamber recirculation channel formed into the die and fluidically coupled to the cross-die recirculation channel to recirculate an amount of printing fluid therethrough, the chamber recirculation channel including a second-sized inlet port and a second-sized outlet port, at least one pump formed within the chamber recirculation channel to recirculate the amount of printing fluid therethrough. |
| US11065878B2 |
Liquid ejection head and liquid ejection apparatus
A liquid ejection head includes a print element substrate including multiple ejection openings, pressure chambers, a common flow path, and pumps, the pumps being configured to circulate liquid between the common flow path and the pressure chamber; and a flow path member laminated to the print element substrate. The flow path member includes a supply flow path and a collection flow path, the supply flow path being configured to supply liquid to the print element substrate, and the collection flow path being configured to collect liquid that is not ejected. The supply flow path and the collection flow path have liquid connection with the same common flow path. A circulating pump generates a flow of liquid flowing in an order of the supply flow path, the common flow path, and the collection flow path, the circulating pump being provided at a position different from the print element substrate. |
| US11065876B2 |
Inkjet printhead with metal alloy shim attachment of printhead chips
An inkjet printhead includes: a manifold having a plurality of ink outlets defined in a manifold surface; a shim adhesively bonded to the manifold surface, the shim having apertures aligned with the ink outlets; at least one row of printhead chips adhesively bonded to the shim. The shim and the manifold are each comprised of an Invar metal alloy. |
| US11065871B2 |
Dye sublimation ink thermal inkjet printing method
A printing method includes selecting a dye sublimation ink, having: a disperse dye colorant dispersion; a primary solvent selected from the group consisting of glycerol, ethoxylated glycerol, 2-methyl-1,3-propanediol, dipropylene glycol, and combinations thereof; a surfactant selected from the group consisting of nonionic surfactants, anionic surfactants, and combinations thereof; an additive selected from the group consisting of a buffer, a biocide, a chelating agent, and combinations thereof; and a balance of water. An operating energy that includes a margin over a turn-on energy (TOE) for a thermal inkjet printhead is applied to a heating resistor of the printhead, wherein the margin ranges from about 10% to about 25% over the TOE. The dye sublimation ink is printed from the thermal inkjet printhead i) directly onto a textile substrate, or ii) onto a transfer medium to form an image thereon; and the image is transferred onto the textile substrate. |
| US11065868B2 |
Jetting devices with acoustic transducers and methods of controlling same
A jetting device configured to jet one or more droplets of a viscous medium through a nozzle may include an acoustic transducer configured to emit an acoustic signal that transfers acoustic waves into at least a portion of the viscous medium located in a viscous medium conduit a viscous medium conduit configured to direct a flow of the viscous medium to an outlet of the nozzle. The acoustic signal may be an ultrasonic signal. The acoustic signal may adjust one or more rheological properties of the viscous medium, based on acoustic actuation. The acoustic transducer may be implemented by an actuator of the device that is configured to move through an eject chamber to cause viscous medium to be jetted through the outlet of the nozzle as one or more droplets. |
| US11065865B2 |
Sheet-fed stamping press having a foil laminating unit
There is described a sheet-fed stamping press (10*) comprising a foil application unit (2*) designed to allow transfer or lamination of foil material onto successive sheets (S), which foil material is fed to the foil application unit (2*) in the form of a foil carrier (FC) supplied by means of a foil feeding system (3). The foil application unit (2*) comprises a stamping cylinder (21) at least one circumferential stamping section (210) provided on a circumference of the stamping cylinder (21) and comprising successive stamping segments (211 *; 211 **) distributed one after the other about the circumference of the stamping cylinder (21), the stamping cylinder (21) also acting as sheet-transporting cylinder and comprising multiple sheet holding units (21a) distributed about the circumference of the stamping cylinder (21) and designed to hold successive sheets (S) against the circumference of the stamping cylinder (21). The foil application unit (2*) further comprises a plurality of counter-pressure units (25) distributed about a portion of the circumference of the stamping cylinder (21) and designed to press the successive sheets (S) and the foil carrier (FC) against an outer surface of the stamping segments (211 *; 211 **), the foil carrier (FC) being supplied by the foil feeding system (3) between the sheets (S) and the stamping segments (211 *; 211 **). Each counter-pressure unit (25) is designed as a cylinder unit (250, 255) provided with at least one circumferential pressing element (255) positioned to cooperate with the circumferential stamping section (210) of the stamping cylinder |
| US11065859B2 |
Device and method for disassembling solar cell module
A solar cell module disassembling device is disclosed. The device of present invention comprises a frame unit, wherein a laminated panel having a first panel and a second panel is mounted on the frame unit, and wherein the first and second panels are stacked and bonded; a guide module, being elongated in a forward and backward direction; a scraper unit, being movably coupled to the guide module, having a blade module, wherein the blade module moves in the forward and backward direction and presses the laminated panel and disassembles the laminated panel; and a transfer unit, being coupled to the scraper unit, delivering a driving force to the scraper unit, transferring the scraper unit. |
| US11065855B2 |
Infrared-reflecting optically transparent assembly and method of making the same
A method of making an infrared-reflecting optically transparent assembly comprises: coating a curable composition onto a major surface of an optically transparent thermoplastic polymer film; at least partially curing the curable composition, which may be optionally at least partially dried, to provide a thermoformable composite film; and laminating the thermoformable composite film to an infrared-reflecting multilayer optical film to provide the infrared-reflecting optically transparent assembly. The curable composition comprises urethane (meth)acrylate compound, (meth)acrylate monomer, and silicone (meth)acrylate. The infrared-reflecting optically transparent assembly and methods of including it in an infrared-reflecting lens assembly are also disclosed. |
| US11065852B2 |
Adhesive film
An embodiment provides an adhesive film having, in order from the surface layer side, a first hard coat, a second hard coat, a transparent resin film layer, and an adhesive layer. The first hard coat is formed from a coating that does not include inorganic particles. The second hard coat is formed from a coating that includes inorganic particles. The adhesive film satisfies the following conditions: (i) the total light transmittance is at least 85%; and (vii) the pencil hardness of the first hard coat surface is at least 5H. Another embodiment provides an adhesive film having, in order from the surface layer side, a first hard coat, a second hard coat, a transparent resin film layer, and an adhesive layer. The first hard coat is formed from a coating that does not include inorganic particles. The second hard coat is formed from a coating that includes inorganic particles. The adhesive film satisfies the following conditions: (i) the total light transmittance is at least 85%; (iv) the water contact angle at the first hard coat surface is at least 100 degrees; and (v) the water contact angle at the first hard coat surface after 20,000 reciprocal cotton rubs is at least 100 degrees. |
| US11065849B2 |
Waterproofing membrane with a solid filler component
The invention is directed to a membrane used in waterproofing and roofing applications, the membrane comprising a barrier layer S1 comprising a thermoplastic polymer component P1 and a contact layer S2 bonded to at least portion of the barrier layer S1, the contact layer S2 comprising a mixture of a solid filler component F and a thermoplastic polymer component P2. The invention is also directed to a method for producing the membrane, a method for waterproofing a substrate, to a waterproofed construction, to a method for sealing a substrate against water penetration and to a sealed construction for sealing a substrate against water penetration. |
| US11065845B2 |
Electrochromic window fabrication methods
Methods of manufacturing electrochromic windows are described. Insulated glass units (IGU's) are protected, e.g. during handling and shipping, by a protective bumper. The bumper can be custom made using IGU dimension data received from the IGU fabrication tool. The bumper may be made of environmentally friendly materials. Laser isolation configurations and related methods of patterning and/or configuring an electrochromic device on a substrate are described. Edge deletion is used to ensure a good seal between spacer and glass in an IGU and thus better protection of an electrochromic device sealed in the IGU. Configurations for protecting the electrochromic device edge in the primary seal and maximizing viewable area in an electrochromic pane of an IGU are also described. |
| US11065841B2 |
Asphaltic sheet materials including expandable graphite
A method for producing an asphaltic sheet, the method comprising of providing an asphaltic sheet; and applying expandable graphite particles to the asphaltic sheet. |
| US11065837B2 |
Foam product
A foam product includes a foam core, a soft skin covering the foam core, and a base structure on which the foam core is disposed. The foam core of expanded beads has an outer surface on which some outermost beads of the expanded beads are exposed and bulging outward with different heights to form a bubbly texture. The foam skin has an inner surface attached to the outer surface of the foam core, and has at its inner surface a plurality of concave cavities each matedly surrounding a respective one of the bulging, outermost beads on the outer surface of the foam core. |
| US11065836B2 |
Glass plate module
The present invention provides a glass plate module to be attached to a vehicle. The glass plate module includes laminated glass in which an outer glass plate, an interlayer, and an inner glass plate are layered in this order; a mask layer that is provided on the laminated glass and blocks a field of vision from outside; and an attachment member that is attached to a portion corresponding to the mask layer on the inner glass plate with at least a first adhesion means and a second adhesion means and configured to support an information acquisition device for acquiring information from outside of a vehicle. The first adhesion means includes adhesive at at least one location. The second adhesion means is configured such that the adhesive conducts preliminary fixing prior to curing. The attachment member includes a fixation portion that faces the mask layer and has a bonding surface provided with the adhesion means. The fixation portion includes at least one adhesive confirmation portion through which the adhesive applied to the bonding surface can be seen from the vehicle interior side. |
| US11065829B2 |
Fiber-reinforced resin intermediate material, fiber-reinforced resin molded article, and method for producing fiber-reinforced resin intermediate material
The fiber-reinforced resin intermediate material according to the present invention is formed by attaching a resin powder to an outer surface of a reinforcing fiber substrate formed of reinforcing fibers and heating it to melt the resin powder to the outer surface of the reinforcing fiber substrate so as to have an uneven shape derived from the resin powder and also have an opened void space. |
| US11065827B2 |
Thermoplastic composite in-situ melt processing method for composite overwrapped tools
An in-situ melt processing method for forming a fiber thermoplastic resin composite overwrapped workpiece, such as a composite overwrapped pressure vessel. Carbon fiber, or other types of fiber, are combined with a thermoplastic resin system. The selected fiber tow and the resin are prepared for impregnation of the tow by the resin. The resin is melted; and, carbon fiber is impregnated with the melted resin at the filament winding machine delivery head. The molten state of the composite is maintained and is applied, in the molten state, to the heated surface of a workpiece. The portion of the surface being wrapped is heated to the melting point of the thermoplastic resin so that the molten composite more efficiently adheres to the heated surface of the workpiece and so that the uppermost layer of fiber resin composite is molten when overwrapped resulting in better adherence of successive layers to one another. |
| US11065826B2 |
Method for manufacturing a part made of composite material
A method for manufacturing a part made of composite material. The method is performed by a system providing a mandrel around which a composite material is wound, and a reel around which a strip of the composite material comes to be wound. |
| US11065825B2 |
High temperature composite seal
A method of sealing a first component to a second component comprising the steps of locating at least one fiber reinforced polyimide resin layer against a first sealing surface on a first component and against a second sealing surface on a second component. At least one fiber reinforced polyimide resin layer is compressed against the first sealing surface and the second sealing surface prior to curing at least one fiber reinforced polyimide resin layer. At least one fiber reinforced polyimide resin layer is heated to promote flow and conformation to the first sealing surface and the second sealing surface. At least one fiber reinforced polyimide resin layer is cured to provide a fluid tight seal between the first component and the second component. |
| US11065824B2 |
Device and method for producing packaging precursors by means of a heating device acting on the edge area of the packaging precursor
The invention relates in general terms to a device for production of a packaging precursor, wherein the packaging precursor consists to an extent of at least 80% by weight, based on the packaging precursor (1000), of a sheetlike composite, wherein the sheetlike composite includes: i. a composite plastic layer, ii. a composite carrier layer, iii. a first composite edge region, iv. a second composite edge region, wherein the device includes, as device constituents in a flow direction: a) a flat transport unit designed to transport the flat sheetlike composite, wherein the transport unit includes a transport surface designed to bear the composite; downstream of that b) a first heating unit designed to heat the first composite edge region, where the first heating unit includes energy release segments; downstream of that c) a contacting unit designed to bond the first composite edge region to the second composite edge region; wherein the first heating unit is designed to release energy in the flow direction. The invention further relates to a method, to a packaging precursor obtainable by the method, to a packaging precursor and to a use of the device. |
| US11065821B2 |
Vibration welding device, method for connecting at least two elongated components by vibration welding, and a production method for the vibration welding device
A vibration welding device having a mechanically coupled multiple vibrator. Within this vibration welding device, the plurality of vibration units are arranged relative to an elongated tool such that the first direction of vibrations of the individual vibration units is oriented approximately transverse to a longitudinal axis of the tool such that, during a vibration welding process, two components are weldable to each other by vibrations different than a longitudinal direction of the components. |
| US11065816B2 |
Manufacture of three dimensional objects from thermosets
A method for creating a three dimensional (3D) object from reactive components that form a thermoset product. In one embodiment, a method includes providing first and second reactive components that are effective to form the thermoset product. In one embodiment, the thermoset product includes a urethane and/or urea-containing polymer. In one embodiment, the first reactive component includes an isocyanate and the second reactive component includes a polyol having at least one terminal hydroxyl group, a polyamine having at least one amine that includes an isocyanate reactive hydrogen, or a combination of the polyol and the polyamine. In one embodiment, the first reactive component includes a prepolymer, and optionally the ratio of viscosity of the first and second reactive components is from 1:3 to 3:1. Also provided is a 3D object that includes a completely reacted thermoset product, and a thermoset system that includes a first and a second reactive component. |
| US11065815B2 |
Powder dispensing assembly for an additive manufacturing machine
A powder dispensing assembly for an additive manufacturing machine includes a hopper defining a powder reservoir for receiving additive powder and a plurality of powder distribution modules operably coupled with the hopper. The powder distribution modules include a powder distribution body defining a discharge orifice and a supply gate that fluidly couples the powder reservoir to the discharge orifice. A plunger valve is movably mounted over the discharge orifice and an actuator moves the plunger valve between an open position and a closed position to selectively dispense a flow of additive powder. |
| US11065814B2 |
Heating device for additive manufacturing, heating module and manufacturing apparatus therewith
The present application provides not only a heating device for additive manufacturing but also a heating module and a manufacturing apparatus utilizing the heating device. The heating device utilizes a rotational reflective cover to modulate a heating direction of a heating source, which expands an area correspondingly irradiated by the heating source and enhances uniformity of heating. Besides, the heating modules can be coupled and controlled by a controlling subsystem so as to respectively irradiate different areas with ranges at least partially intersecting each other, which also improves heating uniformity for heating a large area. |
| US11065813B2 |
Apparatus for additively manufacturing three-dimensional objects
Apparatus (1) for additively manufacturing of three-dimensional objects by means of successive layerwise selective irradiation and consolidation of layers of a build material which can be consolidated by means of an energy beam, with a stream generating unit (2) configured to generate a stream of a process gas (3) being capable of being charged with particles (4), in particular non-consolidated particulate build material and/or smoke and/or smoke residues, generated during operation of the apparatus (1) and a filter unit (5) configured to separate particles (4) from the stream of process gas (3), wherein the filter unit (5) comprises a filter chamber (6) with at least one filter element (7) at least partly arranged in the streaming path of the generated stream of process gas (3), wherein particles (4) in the stream of process gas (3) are separated from the process gas (3) by the filter element (7). |
| US11065812B2 |
Powder module device for an apparatus for additively manufacturing three-dimensional objects
Powder module device (1) for an apparatus for additively manufacturing three-dimensional objects by successive layerwise selective irradiation and consolidation of layers of a powdered build material (2). The device includes a powder module (3), comprising a powder module base body (6) to receive a powdered build material (2), comprising wall elements; delimiting a build material receiving volume (9) for receiving a powdered build material (2) and an opening (10) for introducing powdered build material (2) into the build material receiving volume (9); a lid (4), comprising a lid base body (11) connected to the powder module base body (6) so as to close the opening (10) of the powder module base body (6) in a closed state of the powder module device (1); and a sealing device (5) configured to seal between the powder module (3) and the lid (4) in the closed state of the powder module device (1). |
| US11065811B2 |
Three-dimensional printer head including an automatic touchdown apparatus
A three-dimensional printer head includes a drive motor, the drive motor including a drive shaft, a feed plate is affixed to the drive motor, and a feed hob is mounted to the drive shaft. The feed hob includes drive teeth configured to engage a filament. An idle assembly mounted to the feed plate configured to bias the filament against the drive teeth. The printer head further includes a z-axis plate assembly, wherein the z-axis plate assembly includes at least two flexures coupling a z-axis plate to the feed plate and a print nozzle mounted to the z-axis plate assembly. The printer head also includes a sensor coupled to the feed plate, wherein the sensor is configured to be triggered by the z-axis plate assembly when the z-axis plate assembly moves a given distance in a first direction. |
| US11065806B2 |
Apparatus for longitudinal orientation of thermoplastic film material
Apparatus for longitudinal orientation of thermoplastic film material (4) comprises a width-reduction zone upstream of the longitudinal stretching zone, through which the width of the film is gradually reduced so as to allow longitudinal stretching without necking. The width-reduction zone comprises at least one, preferably several, pairs of pleating rollers (16, 17) comprising intermeshing grooves or discs for pleating the material, the length of said width reduction zone preferably being less than 3 times the original width of the film. The width-reducing zone has upstream (14) and downstream (15) rollers or roller assemblies, with curved axes and optionally also conveyor belts for providing smooth width reduction. Longitudinal stretching is preferably between at least two, and preferably more than two, pairs of stretching rollers (9, 10, 11, 12) which are relatively close together. The pleats may be provided in several stages with increasing pleats per stage, while guiding means preferably lay all the pleats to one side. The apparatus allows achievement of high tensile strength, yield point, resistance to tear propagation and puncture resistance, especially for polyethylene and polypropylene films. |
| US11065801B2 |
Injection stretch blow molding machine and method for manufacturing hollow molded body
Fixation of a container shape of a hollow molded body is not completed during a blow molding process but is completed during an ejection process of an ejection section, thereby shortening an operation time in a stretch blow molding section, and improving the production efficiency of hollow molded bodies by shortening the time required for the blow molding process during a molding cycle.Cooling air is blown into the inside of the hollow molded body disposed in the ejection section in the ejection process C during the blow molding process B in the next molding cycle to cool the hollow molded body disposed in the ejection section to solidify the container shape. |
| US11065789B2 |
Method for establishing of erosion resistant surface part on a wind turbine blade, method for creation of an erosion resistant coating, wind turbine blade with retrofitted coating in and around areas where the blade is especially exposed to erosion damages, coating for mounting on a wind turbine blade's front edge
This invention relates to a wind turbine blade with retrofitted coating in and around areas where the blade is especially exposed to erosion damages, which is established by the coating including a glue layer, a fiber reinforced polymer layer and one or more non-reinforced polymer layers over the fiber reinforced layer, since the polymer layers stretch themselves out over the fiber reinforced layer and includes areas of the wind turbine blade's surface, which are less exposed to erosion damages. A method for creation of such a wind turbine blade and creation of such a coating and the coating itself, is also established with the invention. |
| US11065787B2 |
Composite forming jig and composite forming method
A composite forming method includes manufacturing either one of a composite structure body and a dry preform having a hollow region, and pulling a core out of the hollow region. In the manufacturing, a rubber-made core having a tubular structure is disposed at a portion that forms the hollow region of either one of the composite structure body and the dry preform. The core has a thickness varied in a direction perpendicular to a longitudinal direction to be foldable inward at a thin portion. In the pulling, the core is folded inward with air being discharged from an inside of the core after either one of the composite structure body and the dry preform is manufactured. |
| US11065784B2 |
Method and a tool for assembling a female mould and a female mould arrangement
A method for assembling a female mould on a moulding machine, comprises the steps of: providing a pre-assembled female mould arrangement, the pre-assembled female mould arrangement comprising a plurality of components including at least a base, a forming device having a forming cavity and a fastening element which renders the forming device fixed relative to the base; placing the pre-assembled female mould arrangement on a support of the moulding machine; fixing the pre-assembled female mould arrangement to the support. |
| US11065783B2 |
Silicon ingot slicing apparatus using microbubbles and wire electric discharge machining
Provided are a silicon ingot slicing apparatus capable of slicing silicon ingots in various forms such as blocks or wafers using microbubbles and wire electric discharge machining. |
| US11065782B2 |
Method for casting a construction element
The present invention relates to a method for casting building material to form a construction element using a computer-controlled apparatus. The method comprises the steps of: moving the material deposition head and selectively depositing material, to fabricate a formwork; pouring building material in contact with at least a portion of the formwork; at least partially curing the building material, thereby forming the construction element; and removing at least a portion of the formwork from the construction element. |
| US11065780B2 |
Adjusting mechanism for a cutting tool
An adjusting mechanism for a cutting tool having knife holders circumferentially interspaced and having a back surface facing a circumferential direction and a seat surface facing a radial direction. The mechanism includes a support member having fixation points securable to the cutting tool. A deformable member is sandwiched between the cutting tool and the support member. The deformable member defines an adjustable lateral reference surface facing an axial direction to be in abutment with the knife inserts. An adjustment member is mounted on one of the support member and the deformable member between the fixation points of the support member. The adjustment member is operable to exert a force on the deformable member to locally deform the deformable member from an undeformed state to a deformed state. An axial distance between the support member and the deformable member is greater in the deformed state than in the undeformed state. |
| US11065779B1 |
Coping sled with improved hold down clamp
A coping sled with improved hold down clamp for clamping a piece of wood while cutting the piece of wood with a cutting tool. More specifically, the coping sled of the present invention provides various systems to eliminate unintended movement and facilitate different types of intended movement: lateral, horizontal, vertical, and pivotal. |
| US11065778B2 |
Optical fiber cutter
An optical fiber cutter includes a base that includes a pair of clamps, a blade member moving base that includes a disk-shaped blade member and is configured to move the blade member and bring an outer circumferential edge of the blade member into contact with a surface of the optical fiber, and a pressing that press-bends a scratched portion of the optical fiber to cut the optical fiber. The blade member is rotatably fixed to the blade member moving base to change a position of the outer circumferential edge to be in contact with the optical fiber. The base further includes a rotating member that is rotatably fixed to the base and configured to rotate to transmit power to rotate the blade member, and power transmission between the blade member and the rotating member is releasable. |
| US11065757B2 |
Hybrid single and double wall case
A hybrid double and single wall case with two pivotally connected body portions which are single molded pieces that pivot between an open position and a closed position to respectively receive and contain a chainsaw. A portion of the body sections is configured as a double wall structure and a portion of one of the body sections is configured as a single wall structure. |
| US11065753B2 |
Load-based control of breaker machine
A breaker machine includes a power source, a tool holder arranged to receive a tool and a power driven striking mechanism arranged to strike a tip of the tool with a striking frequency on a hard surface. The breaker machine further includes control circuitry arranged to control an output from the power source and load detection means arranged to detect the load of the power source and transmit information relating to the detected load of the power source to the control circuitry. The control circuitry is arranged to receive information relating to a load of the power source, select a striking frequency based on the information relating to the load of the power source and to apply the selected striking frequency by ramping a current striking frequency to the selected striking frequency based on a predetermined ramping scheme by controlling the output from the power source. |
| US11065752B2 |
Staple gun
A staple gun is provided, including: a main body, including a bottom side, and an abutting portion, a staple outlet and a notch which are disposed on the bottom side; a staple magazine, being withdrawably received within the main body; a lock mechanism, including a pressed member disposed on the staple magazine and having a restricting portion movable between a restricting position and a releasing position; wherein when the restricting portion is in the restricting position, the pressed member is located within the notch, the restricting portion is blocked with the abutting portion and the staple magazine is non-withdrawable from the main body; when the pressed member is pressed and moved toward an interior of the main body and the restricting portion is in the releasing position, the restricting portion is unlocked from the abutting portion and the staple magazine is withdrawable from the main body. |
| US11065751B2 |
Labor-saving stapler
A labor-saving stapler is provided, including: a housing, having a nail outlet; a striker, disposed within the housing and movable between a preset position away from the nail outlet and a nailing position near the nail outlet; an energy-accumulating mechanism, including a connection portion connected to the housing and a connection end cooperating with the striker; an operable mechanism, movably connected to the housing and having a depression portion abutable against the energy-accumulating mechanism; a limitation mechanism, connected to the housing, the striker being positionably restricted by the limitation mechanism; wherein when the striker is in a preset position and positionably restricted by the limitation mechanism, the energy-accumulating mechanism is depressible by the depression portion to be in a energy-accumulating state, and when the striker is free of restriction by the limitation mechanism, the energy-accumulating mechanism actuates the striker to move toward the nailing position. |
| US11065750B2 |
For a gas-powered fixing tool
The present disclosure concerns improvements for a gas-powered fixing tool, and particularly a combustion chamber or precombustion chamber for a gas-powered fixing tool, a working chamber for a gas-powered fixing tool, a fuel gas injection device for a gas-powered fixing tool and a gas-powered fixing tool including one or more of these elements. |
| US11065748B2 |
Safety member and muzzle of nail gun having the same
A safety member is adapted for use in a muzzle of a nail gun. The muzzle defines a nail passage that is for passage of a nail, and a gap that spatially communicates with the nail passage. The safety member is slidable in a nail striking direction of the nail, and includes a slider adapted to be disposed in the gap, and having a flat surface, a platform and an abutment end. The flat surface is adapted to face the plate member. The platform protrudes from the flat surface toward the plate member and cooperates with the plate member to define a nail ejection opening therebetween. The abutment end extends from the platform and extends beyond the nail ejection opening for contact with an object to be fastened. |
| US11065747B2 |
Drive-in tool with improved safety device
A drive-in tool for driving fasteners into a workpiece, wherein the tool comprises in particular: a safety device for transferring the drive-in tool from a trip-ready state into a secured state after expiry of a delay, wherein the safety device comprises a control volume and an activation element, wherein in the first position of the activation element a charging connection is defined between the control volume and the gas pressure source connection, and wherein in the second position of the activation element a discharging connection is defined between the control volume and a pressure sink, wherein one connection from the charging connection and the discharging connection comprises a smallest cross-sectional flow area which, together with a gas pressure of the gas pressure source, determines the delay time of the safety device. The present disclosure also relates to a corresponding method for operating a drive-in tool. |
| US11065746B2 |
Method for clamped joint seating detection
A method for filtering data derived from a process wherein the data is generated by an input of energy. The method includes these steps: collecting the data from the process to create a parent data set; creating a first window of data; calculating an average of the first window of data; comparing the average of the first window of data to a first threshold value; shifting the first window if the average has not passed the first threshold value; creating a second window of data from the parent data set; calculating an average of the second window of data; comparing the average of the second window of data to the threshold value; shifting the second window if the average of the second window of data has not passed the threshold value; and confirming that the threshold value has been reached if the second window average has passed the threshold value. |
| US11065744B2 |
Tool bit holder
A tool bit holder includes an inner sleeve in which a longitudinal bore is defined in which a tool bit is receivable and a detent is engageable with the tool bit for locking the tool bit within the longitudinal bore. An outer sleeve surrounds the inner sleeve and is movable relative to the inner sleeve between a locking position, in which the detent is engaged with the tool bit for locking the tool bit within the longitudinal bore, and a release position, in which the detent may be disengaged from the tool bit to permit removal of the tool bit from the longitudinal bore. A spring is positioned between the inner sleeve and the outer sleeve. The spring biases the outer sleeve toward the locking position. |
| US11065743B2 |
Tool holder device
A tool holder device includes a receptacle having two conduits perpendicular to each other, a spindle and a shaft are rotatably engaged in the conduits of the receptacle and have bevel gears meshed with each other for allowing the shaft to be rotated relative to the receptacle by the spindle, a housing is secured to the receptacle, a flexible shank is secured to the spindle, a stem is secured to the flexible shank, a flexible sheath is engaged onto the flexible shank and is secured to the receptacle, and a control ferrule is secured to the flexible sheath, and the stem is rotatably received and engaged in the control ferrule. The flexible shank and the flexible sheath allow the tool holder device to be easily operated by the user in a tiny working space. |
| US11065738B2 |
Electrical device aligning tool and method of using same
Embodiments disclosed herein include devices and methods for aligning an electrical device. The electrical device aligning tool may include a body member, comprising an end panel at each opposing longitudinal end of the body member and forming a longitudinally perpendicular angle with the body member. The tool may also include an intersecting member coupled to the body member and positioned such that a length of the intersecting member longitudinally intersects the body member at an angle. Additionally, the intersecting member may include an expanding and contracting mechanism, and lateral members coupled to the expanding and contracting mechanism such that the lateral members move horizontally along a front surface of the intersecting member, with respect to a movement of the expanding and contracting mechanism. |
| US11065737B2 |
Needle-nose pliers
A pinching portion of needle-nose pliers is provided with pinching portion lateral width usage scale marks having widths corresponding to first integral multiples of a pitch of a universal board and pinching portion longitudinal length usage scale marks having lengths corresponding to second integral multiples not less than the first integral multiples. In accordance with this configuration, a jumper wire with a required length is obtained. |
| US11065735B2 |
Manufacturing method of carrier for double-side polishing apparatus and method of double-side polishing wafer
A manufacturing method of a carrier for a double-side polishing apparatus, including: preparing a carrier base material and insert thicker than the carrier base material, inserting the insert into a holding hole so as to protrude the insert from both sides of the front surface and back surface of the carrier base material, measuring each of a front protruding amount of the insert protruded from front surface of the carrier base material and a back protruding amount of the insert protruded from back surface of the carrier base material, setting each rotational speed of the upper turn table and lower turn table in starting-up polishing of the carrier so as to decrease the difference between the front protruding amount and back protruding amount, and a starting-up polishing step to subject the carrier to starting-up polishing at each set rotational speed of the upper turn table and the lower turn table. |
| US11065731B2 |
Clamping device
A clamping device includes a clamping chuck and a clamping element, which can be clamped thereto. The clamping chuck has a receiving opening for the clamping element and clamping members for clamping the clamping element in the receiving opening. The clamping element is elongated, while the clamping chuck is provided with an elongated receiving opening for the clamping element. A resiliently flexible centering element, which aligns the clamping element in response to the insertion into the receiving opening at right angles to the longitudinal axis of the receiving opening, is arranged on the clamping chuck in the insertion area of the receiving opening. Such a clamping device is suitable in clamping systems by means of which large to very large workpiece carriers can be clamped in the work area of a machine tool in a repeatably accurate manner. |
| US11065730B2 |
Work piece mounting system
The present concept a work piece mounting system for connecting two work elements together, includes a main body with radially oriented horizontal upper and lower jaw passageways for receiving therein upper and lower jaws respectively. The radially oriented horizontal upper and lower jaw passageways, are adapted to receive the jaws slid-ably therein, wherein the cross section of the jaws and passageways configured such that the jaws are restricted from rotating within the passageways. A vertical cavity extending vertically and centrally through the main body, along a z-axis, is for receiving a grooved end of a lower fixation element upwardly therein and a grooved end of an upper fixation element downwardly therein, wherein the other threaded end of the fixation elements are configured for detachably connecting to a working element. Wherein the jaws include a grooved portion for engaging with a grooved end of the fixation elements and are configured such that the fixation elements are drawn into the main body upon engagement of the grooved portions with the grooved ends thereby tensioning the fixation elements between the main body and a work elements. Further the angular relationship between the upper jaw passageway and the lower jaw passageway in a horizontal plane x-y relationship is selected to be able to nest the passageways to minimize a thickness T of the main body for improved rigity and dimensional stability of the work piece mounting system. |
| US11065729B2 |
Insertion device and method for inserting a circular blank ring into an outer ring of a circular blank
An outer ring (29) is first transported to an insertion point (E) in the feed device (34). At the same time, a circular blank ring (30) is brought into a starting position (P) in the feed device. The circular blank ring (29) is first aligned coaxially with respect to an axis (A) using a centering body (61). The circular blank ring moves solely radially with respect to the axis (A). The circular blank ring (30) is then inserted into the hole of the outer ring (29). During this movement, the circular blank ring is aligned coaxially with respect to the axis (A) preferably using a centering channel (54). The circular blank ring (30) carries out a superimposed movement in the axial direction (V) and in the radial direction radially with respect to the axis (A). |
| US11065724B1 |
Laser weldable compositions, products and uses thereof
Laser weldable compositions are provided which in various examples include a tricyclodecane dimethanol-modified copolymer, a terephthalate-type polyester and an inorganic filler. Compared with compositions without the tricyclodecane dimethanol-modified copolymer, the compositions of the invention have improved, uniform laser transmittance, thereby welded products including the compositions have improved bonding strength and require stronger tensile strength to be torn apart. |
| US11065723B2 |
Laser etching apparatus and a method of laser etching using the same
A laser etching apparatus includes a chamber, a laser port, a laser emitter, a particle grabber, and a revolving window module. The chamber is configured to receive a substrate. The laser port is disposed below the chamber in a downward direction. The laser emitter is configured to emit a laser to the substrate disposed within the chamber through the laser port. The particle grabber is disposed within the chamber and includes a body disposed over the laser port. An opening is formed through the body. The opening is configured to pass the laser therethrough. The revolving window module includes a revolving window and a driving part configured to drive the revolving window. The revolving window is disposed between the particle grabber and the laser port. |
| US11065721B2 |
Method for determining the reference focal position of a laser beam
A method for determining a reference focal position of a laser beam for processing a plate-like member, the method comprising producing at least two incisions in the plate-like member with the laser beam set at different focal positions, irradiating the plate-like member with the laser beam, detecting edges of the incisions by measuring one or more parameters relating to the irradiation of the plate-like member, and establishing a width of the at least two incisions using the detected one or more parameters. |
| US11065717B2 |
Laser processing apparatus
A laser beam applying unit of a laser processing apparatus includes a laser oscillator, a condenser adapted to focus the laser beam emitted from the laser oscillator and apply the laser beam to a workpiece, and a liquid jetting apparatus disposed at a lower end portion of the condenser and adapted to jet a liquid to an upper surface of the workpiece. The liquid jetting apparatus includes: a transparent plate disposed at the lower end portion of the condenser and permitting transmission therethrough of the laser beam; a casing provided with a space defined by a ceiling wall composed of the transparent plate, side walls, and a bottom wall; an opening formed in the bottom plate, extending in a processing feeding direction, and permitting passage therethrough of the laser beam focused by the condenser; and a liquid supply section adapted to supply the liquid to the casing. |
| US11065715B2 |
Combined liquid guided laser and electrical discharge machining
This disclosure provides a system, method, and resulting workpiece combining liquid guided laser and electrical discharge machining to create a common feature. The workpiece is positioned in a liquid guided laser cutting path and machined by the liquid guided laser device to create an intermediate feature in the workpiece. The work piece is then positioned in an electrical discharge machining (EDM) device so that an electrode of the EDM device is operatively positioned proximate the intermediate feature and machined using the EDM device to modify the intermediate feature in the workpiece to create the finished common feature in the workpiece. |
| US11065710B2 |
Resistance spot welding workpiece stack-ups having a steel workpiece and an aluminum workpiece with a steel plate
A method of resistance spot welding a workpiece stack-up. The workpiece stack-up includes at least a steel workpiece and an aluminum workpiece. The method involves attaching a steel plate to the steel workpiece at a weld-site of the workpiece stack-up, passing electrical current between a first welding electrode and a second welding electrode at the weld-site, and terminating passage of electrical current between the first and second welding electrodes in order to form a weld joint. The steel plate serves to stiffen the weld joint. |
| US11065705B2 |
Fillet welding method and fillet welded joint
A welding method for obtaining a lap fillet welded joint excellent in tensile strength, without causing an increase in welding deformation, not fracturing at the weld metal when a tensile load is applied, that is, a method of overlaying at least scheduled welding locations of a first steel sheet with a tensile strength of 780 MPa or more and a second steel sheet and fillet welding an end part of the first steel sheet and a surface of the second steel sheet, characterized by providing a reinforcing part at a surface of the first steel sheet at the opposite side to the surface to be overlaid with the second steel sheet and fillet welding one end part of the reinforcing material and the surface of the first steel sheet and by fillet welding the end part of the reinforcing part, the end part of the first steel sheet, and the surface of the second steel sheet so as to be covered by the weld metal. |
| US11065701B2 |
Tap
A tap 1 has a threaded portion 2 including a cutting blade 5 on an outer circumferential surface, a flute portion 3 that divides the threaded portion 2 in a circumferential direction, and a shank portion 4 formed continuously from the threaded portion 2 and the flute portion 3 along a central axis O. The flute portion 3 includes, in a cross-sectional view, a first flute 31 formed continuously from the cutting blade 5 of the threaded portion 2, a second flute 32 formed continuously from the first flute 31, and a ridge line portion 33 being a boundary between the first and second flutes 31, 32. A distance “e” from the central axis O to the ridge line portion 33 is longer than a distance d1 and a distance d2, respectively. |
| US11065700B1 |
Post notch forming tool and related methods
Post notch forming tool mounted on a handheld saw blade for forming a notch in a post end. The tool has a base, a handle, and two L-shaped members with bolt assemblies for attaching the tool to the saw blade. The base has a first extended lip which slides downwardly along the post's outer surface to guide the tool to form a 3-inch notch. A spacer member is selectively attached to the L-shaped members and has a second extended lip which slides downwardly along the post's outer surface to guide the tool to form a 1½ inch notch. Method steps include using the power saw blade to form a transverse cut intersecting the longitudinal axis, using the extended lip of the base to form a 3-inch notch, or attaching the spacer member and using its extended lip to form a 1½ inch notch in the post's outer surface. |
| US11065694B2 |
Alignment system, drilling system, and method for drilling a hole through a gang channel
Example alignment systems for aligning a drill bit with respect to a gang channel and methods of use are described herein. An example alignment system for use with a drill includes a drill block having a guide portion and an attachment portion. The attachment portion is configured to be removably coupled to a foot of the drill such that the drill block is positioned between the foot and a drill bit of the drill. A longitudinal axis of the drill block is coaxial with a longitudinal axis of the drill bit when the attachment portion is coupled to the foot. The guide portion is configured to at least partially contact an inner surface of opposing legs of a gang channel to thereby center the drill bit between the opposing legs of the gang channel. |
| US11065692B2 |
Diamond-coated tool
A diamond-coated tool includes: a substrate; and a diamond layer that coats the substrate, wherein the diamond layer includes a first region that is in contact with the substrate, the first region includes a region S1 surrounded by an interface P between the substrate and the diamond layer and an imaginary plane V1 separated from the interface P by a distance of 2 μm, and the region S1 has crystal grains grown in random directions. |
| US11065690B2 |
Powder deposition apparatus and a method of using the same
A powder deposition apparatus has a build plate, a powder source, a recoater arm, and an energy beam. The recoater arm is formed from ferromagnetic material.The recoater arm is arranged to deliver a layer of powder from the powder source across the working surface of the build plate prior to the energy beam fusing a predetermined portion of the delivered powder layer. The recoater arm comprises a magnetic portion. |
| US11065688B2 |
Nano-particles containing carbon and a ferromagnetic metal or alloy
The invention relates to nano-particles comprising metallic ferromagnetic nanocrystals combined with either amorphous or graphitic carbon in which or on which chemical groups are present that can dissociate in aqueous solutions.According to the invention there is provided nano-particles comprising metal particles of at least one ferromagnetic metal, which metal particles are at least in part encapsulated by graphitic carbon.The nano-particles of the invention are prepared by impregnating carbon containing bodies with an aqueous solution of at least one ferromagnetic metal precursor, drying the impregnated bodies, followed by heating the impregnated bodies in an inert and substantially oxygen-free atmosphere, thereby reducing the metal compounds to the corresponding metal or metal alloy. |
| US11065674B2 |
Fastening tool
A fastening tool includes a fastener-abutment part, a pin-gripping part, a motor, a driving mechanism, an input-accepting part and a motor-control part. The fastener-abutment part is configured to abut on a cylindrical part of a fastener. The pin-gripping part is configured to grip a portion of a pin of the fastener. The driving mechanism is configured to be driven by power of the motor to move the pin-gripping part rearward along a driving axis relative to the fastener-abutment part, thereby fastening a workpiece via the fastener. The input-accepting part is configured to accept setting information for a control condition of the motor inputted via an operation part configured to be externally operated by a user. The motor-control part is configured to control operation of the driving mechanism by controlling driving of the motor according to the control condition based on the setting information accepted by the input-accepting part. |
| US11065673B2 |
Hot steel forging in horizontal press
The present disclosure relates to a steel forging process, in particular a hot steel forging process in horizontal press of a metal tube, preferably a cylindrical steel tube. |
| US11065670B1 |
Outward direction pipe fitting swage machine systems and methods
Techniques for implementing and/or operating a system that includes a pipe fitting to be secured to a pipe segment, in which the pipe fitting includes a grab ring having a grab notch and a fitting jacket to be conformally deformed around tubing of the pipe segment to facilitate securing the pipe fitting to the pipe segment. The system includes a swage machine, which includes a grab plate having a grab tab that matingly interlocks with the grab notch to facilitate securing the pipe fitting to the swage machine, a die plate including a die that opens away from the grab plate, and a swaging actuator secured to the die plate. The swage machine operates the swaging actuator to move the die plate over the fitting jacket in an outwardly axial direction away from the grab plate to facilitate conformally deforming the fitting jacket around the tubing of the pipe segment. |
| US11065667B2 |
Offset notch bridging connector
A connection between metal studs and bridging members using a separate light gauge bridging connector with longitudinally-offset interface notches. |
| US11065664B2 |
Metal sheet molding method
A machining surface of a die are provided with a pair of inclined surfaces facing each other across a gap and a flat surface interposed therebetween. Each inclined surface includes an inner end portion on a side near the flat surface and an outer end portion on a side farther away from the flat surface. The molding method includes a mounting step of mounting the metal sheet on the die to span both inclined surfaces, and a pressing step of forming a reduced-thickness portion by pressing the metal sheet between the punch and the inclined surfaces of the die. The pressing step includes setting a bottom dead center of the punch to maintain a gap formed between the inner end portion and a surface of the metal sheet facing the inner end portion. |
| US11065661B2 |
Modifiable golf club head
A method of modifying a golf club head including engaging a bending tool with the golf club head and bending at least a portion of a sole of the golf club head by applying force using the bending tool to cause plastic deformation of the sole. The plastic deformation changes a contour of an exterior surface of the sole. According to another aspect, a golf club head includes a striking face including a face center, a top portion, a sole including a leading edge and a trailing edge, and a rear side opposite the striking face. The rear side includes a channel configured to permit bending at least a portion of the sole to cause plastic deformation to change a bounce angle defined as an angle between a virtual sole line and a virtual ground plane when the golf club head is orientated in a reference position. |
| US11065653B2 |
Cleaning apparatus, cleaning method, and imaging apparatus
A determining unit 31 determines an image region of a foreign material in an imaged image generated by an imaging unit 22 by using an imaging optical system 21. A setting unit 32 sets a pressure, injection time, an injection direction of air injected to the foreign material, an injection pattern obtained by combining them and the like based on a determination result. A foreign material removal processing unit 33 adjusts air injection by an air injection adjusting unit 331 based on the setting by the setting unit 32 and injects from an air injecting unit 332 to the imaging optical system 21 to remove the foreign material adhering to the imaging optical system 21. The air is injected according to an adhesion condition of the foreign material, so that the foreign material adhering to the imaging optical system may be optimally removed. |
| US11065652B2 |
Endoscope cleaning station having leak tester and high-pressure port
An endoscope cleaning station for cleaning an endoscope includes a sink having an inlet connected to a water supply for filling the sink and a drain for draining the sink, a fill solenoid for controlling a flow of water to the inlet of the sink, a detergent pump and detergent valve that cooperate to selectively dispense detergent into another flow of water thus creating a detergent solution, a manifold for injecting the detergent solution into the endoscope, a lumen solenoid for controlling the flow of the detergent solution to the manifold, a pressure regulator disposed downstream of the lumen solenoid and upstream of the manifold to reduce a pressure of the detergent solution delivered to the manifold, and a high-pressure port connected to a narrow channel of the endoscope, the high-pressure port receiving the detergent solution that bypasses the pressure regulator so that the detergent solution exiting the high-pressure port into the narrow channel has a higher pressure than the pressure of the detergent solution delivered to the manifold. |
| US11065651B1 |
Vehicle-towed portable power-washing apparatus
The speed, effectiveness, and convenience with which pallets and other objects are cleaned can be increased by using a vehicle-towed portable pressure power-washing apparatus. The apparatus includes a platform that can be towed. On the platform is positioned at least one pressure-washer that pumps liquid from a tank into rotary arms within a cleaning chamber positioned on the platform, causing the rotation of the arms as the arms eject streams of the liquid pumped under a high pressure from angled nozzles. Belt conveyors carry an object in need of cleaning into the cleaning chamber, first exposing the object to the streams of the liquid, and then to a drying chamber. Guide rails positioned on the platform guide the object during cleaning, with the shape of one of the guide rails causing the object to fall off the platform following the drying to remove excess liquid left on the object. |
| US11065650B2 |
Nozzle cleaning device and nozzle drying method
A nozzle cleaning device for cleaning suction nozzle 62, wherein the jetting direction of water jetted towards the tip section of the suction nozzle is changed by a tapered second internal surface 374 of socket 370. Accordingly for example, not only is it possible to appropriately remove items adhering to the lower surface of the tip of the suction nozzle, it is possible to remove items adhering to the side surfaces of the tip of the suction nozzle by applying water. The suction nozzle is cleaned while being supported by nozzle pallet 152; after the suction nozzle is cleaned, the suction nozzle is held by a holding tool and removed from the nozzle pallet. Accordingly, the suction nozzle removed from the nozzle pallet is individually dried by the nozzle drying device. Thus, it is possible to appropriately dry the suction nozzle after cleaning. |
| US11065649B2 |
Implement for cleaning livestock feed bunks
An implement for cleaning debris from feed bunks has a frame adapted to be coupled to a vehicle, a transverse shaft rotatably supported by bearing assemblies on the frame and extending laterally beyond one side of the vehicle, a drive motor for rotatably driving the shaft, and a plurality of strips of flexible material connected to an outer end portion of the shaft. The strips of flexible material can be baler belt sections arranged with a tread pattern on a leading surface to help pick up debris and liquid from feed bunks during operation. The strips of flexible material are attached to mounting surfaces on diametrically opposed sides of the shaft and arranged so that free ends of the strips strike and fling debris from the feed bunk during rotation. The drive motor has an adjustable rotation speed to accommodate differing amounts and conditions of debris in the feed bunk. |
| US11065646B2 |
Sieving apparatus and method of using same
This invention relates to a sieving apparatus and method for separating solid particles above a predetermined size from a fluid by carrying the solids-containing fluid across at least one sieving cloth in a frame connected to a shaking device for providing shaking motion. The sieving apparatus includes an inlet portion for receiving solids-containing fluid, a discharge portion for solids that have been carried across the at least one sieving cloth and an outlet portion for fluid that has passed through the sieving cloth. The sieving apparatus further includes at least one endless sieving cloth arranged for rotating around at least two spaced-apart turning-rollers, at least one being connected to a motor, and a pumping device in fluid communication with a suction nozzle located proximate an underside of the endless sieving cloth between two of the turning-rollers, to produce a fluid flow through at least a portion of the endless sieving cloth. |
| US11065644B2 |
Method for exciting piezoelectric transducers and sound-producing arrangement
A method for exciting sound-wave producing transducers (7) which have operating frequencies defining a transducer frequency range, in which a generator (9) produces an electrical excitation signal for the transducers (7), these electrical excitation signal being fed to the transducers (7), wherein the generator (9) carries out frequency sweeps in a frequency sweep range between a minimum frequency (fmin) and a maximum frequency (fmax) with an adjustable sweep rate, with a target frequency (fZiel) being defined within said frequency sweep range, this method being characterized in that the minimum frequency (fmin), the maximum frequency (fmax) and the target frequency (fZiel) are selected in such a way that a first frequency difference (Δf1) between the minimum frequency (fmin) and the target frequency (fZiel) differs in terms of magnitude from a second frequency difference (Δf2) between the maximum frequency (fmax) and the target frequency (fZiel) within a number of frequency sweeps, and wherein the minimum frequency (fmin) and/or the maximum frequency (fmax) and/or the target frequency (fZiel) is/are modified after at least one frequency sweep in such a way that an arithmetic mean of the first frequency differences (Δf1), formed over all frequency sweeps carried out, and an arithmetic mean of the second frequency differences (Δf2), formed over all frequency sweeps carried out, are substantially the same in terms of magnitude. |
| US11065642B2 |
Multicolor fixture finishes
A method of applying a multi-color finish to a plumbing fixture includes depositing a first coating on the plumbing fixture; selectively applying a masking material in a graduated fashion over at least a portion of the first coating to define a gradient from a first portion of the plumbing fixture that is substantially completely covered by the masking material to a second portion of the plumbing fixture that has substantially no masking material; depositing a second coating over the masking material; and removing the masking material from the plumbing fixture such that the plumbing fixture has a surface finish including a transition region representing a gradual transition between the first coating and the second coating. |
| US11065632B2 |
Conveying device for the conveying of coating powder, powder center with the conveying device, and method for the cleaning of the powder center
A conveying device is provided for the conveying of coating powder and includes a powder reservoir container that includes, on the bottom, a powder outlet channel. The powder outlet channel is connected to a first powder conveyor for conveying powder out of the powder reservoir container back to a powder storage container. Moreover, a second powder conveyor is provided for conveying powder out of the powder reservoir container to a powder applicator. |
| US11065630B2 |
Tool for holding a spray painting instrument for painting an internal surface of a pipe
Disclosed herein is a tool for holding a spray painting instrument, such as a painting gun for painting an internal surface of a pipe. In particular, the inventive tool is ideal for painting the interior of curves and angles in a pipe and is capable of moving through and uniformly painting up to 90 degree angles of pipes or hollow tubes. The tool has a hollow central tube for carrying a spray-painting gun and at least two projections extending outwardly from an outer surface of the hollow tube. A retracting arm assembly is provided on each projection. Each retracting arm assembly includes first and second retracting arms and a corresponding force exertion mechanism. In operation, when the tool is inserted inside the pipe, each retracting arm touches the internal surface of the pipe due to an outward force exerted thereon. The tool is movable inside the pipe and adjusts automatically to different pipe diameters. The tool can be used manually or in an automated fashion to push and pull the paint gun and paint the interior of a pipe. |
| US11065629B2 |
Centrifuge system for separating cells in suspension
An apparatus for separating cell suspension material into centrate and concentrate, includes a single use structure (178, 240, 250) releasably positioned in a cavity in a solid wall rotatable centrifuge bowl (172). The bowl and portions of single use structure rotate about an axis (174). A stationary inlet feed tube (184), a centrate discharge tube (212) and a concentrate discharge tube (230) extend along the axis of the rotating single use structure. A centrate centripetal pump (208) is in fluid connection with the centrate discharge tube. A concentrate centripetal pump (216) is in fluid connection with the concentrate discharge tube. A controller (274) operates responsive to sensors (264, 270) in respective centrate and concentrate discharge lines (262, 268), to control flow rates of a concentrate pump (272) and a centrate pump (266) to produce output flows of cell concentrate and generally cell free centrate. |
| US11065628B2 |
Centrifuge tile assembly
Wear resistant centrifuge tile assemblies include a backing portion and a wear-resistant tile. Wear resistant centrifuge tile assemblies are provided with self-fixturing features to provide a desired mounting position and to restrict movement of the wear-resistant tile with respect to the backing plate during bonding. The self-fixturing features provide the ability to perform repeatable and consistent bonding of the wear-resistant tile to the backing plate. The bonding of the wear-resistant tile to the backing plate can be performed with a braze material. |
| US11065625B2 |
Auger for grinding polyurethane for a tire filling machine
An auger for a grinder material for a tire filling machine, having: a cylindrical column; and a plurality of flights extending outwardly from the cylindrical core, wherein (i) the flights are arranged in pairs extending radially outwards from the cylindrical column at 180 degrees to one another, and (ii) each flight has a sharpened leading edge. Each pair of flights are positioned at angles of approximately 50 or 60 degrees to one another, and each flight extends approximately half way around the circumference of the cylindrical column, and there are no outer edge notches in the flights. |
| US11065623B1 |
Grinding blade for an angle grinder
A grinding blade having a blade body, a plurality of tooth mounts, a plurality of cutting teeth, and a plurality of blade stops is disclosed. The blade body has a front surface, a back surface, and a blade mounting hole along a central axis. The tooth mounts and blade stops are integral with the blade body and protrude upward and away from the back surface and the central axis. Each tooth mount has a cutting tooth releasably coupled through a tooth aperture. The blade stops and tooth mounts are equal in number and are distributed alternatingly and with radial symmetry about the central axis. A cross section of the solid of revolution defined by rotating the blade stops about the central axis overlaps with at least two thirds of a cross section of the solid of revolution defined by rotating the cutting teeth about the central axis. |
| US11065622B2 |
Pipette tip rack plates
Provided herein are pipette tip racks, and in particular, pipette tip rack plates that restrict lateral displacement of pipette tips loaded therein. |
| US11065619B2 |
Cassettes with offset vias
A cassette may include a substrate, a die coupled to the substrate, and an electrical interconnection pad layout formed on a first side of the substrate. The electrical interconnection pad layout may include a first row of interconnect pads including at least one interconnect pad. Each interconnect pad of the first row of interconnect pads may be electrically coupled to one of a first set of vias. The electrical interconnection pad layout may also include a second row of interconnection pads including at least one interconnect pad. Each interconnect pad of the second row of interconnect pads being electrically coupled to one of a second set of vias. The second set of vias electrically coupled to the second row of interconnect pads are offset relative to an alignment of the interconnect pads of the first and second rows. |
| US11065617B2 |
Flow passage design for multi-reaction biological detection and detection method thereof
A flow passage design for multi-reaction biological detection includes a first temporary tank, a second temporary tank, a first microchannel, and a second microchannel. The first temporary tank is configured to temporarily store a first liquid in an initial state. The second temporary tank is configured to temporarily store a second liquid in the initial state. The first microchannel is located upstream of the first temporary tank. The first microchannel has an outlet end and an inlet end, respectively connecting to the first temporary tank and the second temporary tank. The second microchannel is located downstream of the first temporary tank and connects to the first temporary tank. In the initial state, a portion of the first liquid enters the second microchannel, the outlet end of the first microchannel is covered by the first liquid, and the inlet end of the first microchannel is covered by the second liquid. |
| US11065612B2 |
Unitary serological pipette and methods of producing the same
A pipette may comprise a length, a longitudinal axis, and an inner curved surface enclosing a space. The pipette may have a tip region having a tip thickness. The tip region may be connected to a body region having a body thickness. The tip thickness may be greater than the body thickness. The body region may be connected to a mouth region having a mouth thickness. The mouth thickness may be greater than the body thickness. The inner curved surface may not contain bumps or ridges either between the tip region and the body region or between the body region and the mouth region. The pipette may be formed by blow molding or vacuum forming. |
| US11065608B2 |
Multidentate ligands and use thereof
The present invention provides, inter alia, a multidentate ligand having the structure of: Also provided are methods of preparing metal complexes from the multidentate ligand, and the metal complexes prepared by such methods. Further provided are catalysts comprising such metal complexes, and various uses of such catalysts. |
| US11065606B2 |
Metal-substituted beta zeolite and method for producing same
The purpose of the present invention is to provide a metal-substituted beta zeolite that exhibits a more excellent catalytic performance than conventional one, and a method for producing the same. The present invention provides a metal-substituted beta zeolite by subjecting an alkali metal-form beta zeolite produced without using an organic structure-directing agent to ion exchange with ammonium ion and then, using a filter cake procedure, to ion exchange with copper ion or iron(II) ion. The present invention also provides a metal-substituted beta zeolite which has been ion exchanged with copper ion or iron(II) ion and in which the amount of Lewis acid sites is greater than the amount of Bronsted acid sites when the amount of Bronsted acid sites and the amount of Lewis acid sites are measured by ammonia infrared-mass spectroscopy temperature-programmed desorption on the as-produced state. |
| US11065601B2 |
Separation medium
A separation medium for use in the separation of analytes from a feed stream containing suspended solids, processes of separation using the separation medium, and the use of the separation medium to separate analytes from a feed stream containing suspended solids. The separation medium is provided as a hydrogel having a structure whose surfaces are defined by a triply periodic minimal surface, the hydrogel comprising at least one ligand that binds at least one target analyte. |
| US11065598B1 |
Mercury capture using functionalized porous organic polymer with hierarchical porosity
Compositions are provided for binding mercury based in porous organic polymers having (i) a plurality of repeat units having heavy metal chelator moieties covalently attached thereto and (ii) a plurality of pores having a hierarchical pore size distribution over a range of pore sizes. In some aspects, the range of pore sizes is about 5 nm to 10 nm. The compositions can have a maximum mercury uptake capacity of 1,000 mg g−1 to 2,000 mg g−1 at 1 atm and 296 K and has a mercury uptake capacity that is stable and recyclable. Methods of making the compositions and methods of using the compositions for uptake of mercury are also provided. |
| US11065596B2 |
Anchoring mesh for an anti-erosion coating
The invention relates to a metal anchoring mesh intended to be secured to a metal wall of a chamber of a fluid catalytic cracking unit, in order to form cells (64). Said metal anchoring mesh comprises a plurality of wavy elementary parts (12, 14) connected successively together, forming cylindrical surfaces that are able to respectively define said cells, said cylindrical surfaces each having a central axis of symmetry A, the wavy elementary parts (12,14) each having protruding tongues (42′, 44′), said protruding tongues being able to extend respectively inside said cells (64). Said tongues (42′, 44′) extend along a length less than a quarter of the distance d that extends between said cylindrical surface and said central axis of symmetry A of said cylindrical surface. |
| US11065595B2 |
System and method for monitoring and controlling a polymerization system
The present disclosure relates generally to a system having a reactor system with a polymerization reactor and a feed system fluidly coupled to a feed inlet of the reactor. The feed system supplies components to the reactor via the feed inlet, and the reactor has a flow path that continuously conveys the components through the reactor and subjects the components to polymerization conditions to produce a polymer. The system also has an analysis system coupled to the reactor for online monitoring of a particle size of the polymer. Further, the system includes a control system, coupled to the analysis and feed systems, that receives a signal from the analysis system indicative of the monitored particle size of the polymer and adjusts an operating parameter of the feed system to control a flow rate of at least one of the components to the reactor based at least on the signal. |
| US11065592B2 |
Method and system for forming and for catalytically reacting a reactant mixture—embodiment of the reactor
In a process as disclosed according to the present invention, gases or gas mixtures used to form a reactant mixture in an at least temporarily ignitable composition are fed into a mixing chamber (11) through the passages (131) in a boundary wall (13) of the mixing chamber (11) and by means of one or more feed conduits (14) which have feed orifices (141) and extend into the mixing chamber (11), respectively. The present invention likewise provides a corresponding reactor (1). |
| US11065588B2 |
Fluid processing method
A fluid processing method with which processing properties of fluids to be processed can be effectively controlled. Processing surfaces which are capable of being brought closer to each other and being separated from each other, and which rotate relatively are provided. A fluid to be processed is made to pass from inside to outside in a processing area between the processing surfaces to obtain a fluid thin film, and the resultant fluid thin film of the fluid to be processed is subjected to processing. Processing properties are controlled by changing the ratio of the distance to an outer peripheral end from a centre of rotation. |
| US11065584B2 |
Separation membrane module and repairing method thereof
An object of the present invention is to provide a separation membrane module in which an end member is prevented from coming out even at the occurrence of a reverse pressure or the like. The invention relates to a separation membrane module which is equipped with a cylinder-shaped housing and a tubular separation membrane and which takes out a fluid which has permeated the tubular separation membrane. An end pipe is connected to one end portion of the tubular separation membrane; the end pipe is supported by a support plate which is disposed so as to traverse the housing; and an end plug is connected to the other end portion of the tubular separation membrane. The separation membrane module is further equipped with a coming-out preventive member. |
| US11065583B2 |
Separation membranes
A process for the preparation of ultrafiltration and microfiltration polymeric flat sheet separation membranes is disclosed, the process comprising a unidirectional cooling step. Membranes prepared according to the process exhibit numerous advantages over ultrafiltration and microfiltration membranes prepared via conventional processes. In particular, the membranes prepared by the present process exhibit remarkable pure water flux, superior mechanical properties and increased anti-fouling characteristics. Also disclosed are particular PVDF ultrafiltration and microfiltration membranes having improved flux, mechanical and anti-fouling properties. |
| US11065581B2 |
Separation systems for removing starch and other usable by-products from processing waste water
The present invention provides for a method for separating starch from processing solutions containing starch containing plants or roots such as potatoes, sweet potatoes, wheat, corn, tapioca, yams, cassaya, sago, rice, pea, broad bean, horse bean, sorghum, konjac, rye, buckwheat and barley to provide commercially acceptable starch while reducing disposal of solid or liquid waste matter into landfills or water treatment facilities. |
| US11065580B2 |
Separation membrane element
According to the present invention, even when a high recovery ratio operation is performed, the influence of concentration of ingredients to be separated in the feed fluid can be reduced, the concentration polarization can be prevented by increasing the turbulence effect on the membrane surface, and the fluid permeation performance and the separation performance of the separation membrane element can be maintained. |
| US11065575B2 |
Membrane device for water and energy exchange
A device for exchange of water molecule and temperature between two fluids. The device comprises thin molecular sieve membrane sheets that allow water molecules to permeate through while blocking cross-over of the exchanging fluids. The device provides two sets of flow channels having a hydraulic diameter ranged from 0.5 to 2.0 mm for respective process and sweep fluid flows. The two sets of the channels are separated by a membrane sheet having a thickness less than 200 μm. The thin molecule sieve membrane may be prepared by forming an ultra-thin zeolite membrane layer on a porous metal-based support sheet which provides very high water permeance so that the exchange can be conducted in a compact membrane module at high throughput. The device can be used to remove water from a process stream of higher water content by use of a sweep fluid of lower water content or higher water affinity. For example, the device can be used to condition outdoor fresh air close to the temperature and humidity of indoor air by conducting humidity and heat exchange between the fresh air flow drawn from outdoors and waste air discharged indoors. |
| US11065570B2 |
Filter medium and a use thereof
The present invention relates to a filter medium being at least formed of a pre-filter sub-strate laminated with a fine-filter substrate by means of a third binder, wherein the pre-filter substrate comprises synthetic fibers and a first binder, the pre-filter substrate work-ing as a combined surface and depth filter, and the fine-filter substrate comprises at least a second binder and one of synthetic fibers and inorganic fibers. |
| US11065569B2 |
Manifold arrangement
Provided is an improved filtration module assembly comprising a vessel having a filtration cartridge disposed within it and a header coupled to an end of the vessel, the header including a housing having an open-ended upper end and a lower end, and an end cap including a portion that mates with a complimentary structure defined by the inner all of the open ended upper end of the housing to removable engage with the housing and the end cap may further define a passageway for fluid to flow out of the vessel. The filtration module assembly may enable an improved manifold arrangement used to communicate fluids to and from a filtration system comprising a plurality of such modules and the configurations of the present invention may facilitate improved operation of such filtration systems. |
| US11065565B1 |
Quick drain, low mess, hydrostatic transmission filter and plug assembly
A filter component includes a cartridge portion including a filter media, and a plug assembly on which the cartridge portion is mounted and in fluid communication with the cartridge portion. The plug assembly comprises a first plug and a second plug, the first plug being larger than the second plug. The second plug is fixed to an inner surface of the first plug in an installed state and is removable from the first plug in a draining state. The first plug further defines a drain port, wherein in the installed state the second plug plugs the drain port and in a draining state the second plug is removed from the first plug to permit draining fluid through the drain port. The filter component may be incorporated into a hydrostatic transmission to permit controlled draining of fluid from the hydrostatic transmission that does not result in an oil mess. |
| US11065558B2 |
Stationary phase for supercritical fluid chromatography
Provided is a stationary phase for supercritical fluid chromatography, the stationary phase having satisfactory molecule-identifying ability, in particular, satisfactory separating properties with respect to not only acidic compounds or basic compounds but also fused aromatic compounds or aromatic isomers. The stationary phase for supercritical fluid chromatography includes a support having, bonded thereto, a polymer in which the main chain has nitrogenous aromatic rings in the repeating units. |
| US11065557B2 |
Micro device for solid phase extraction
The present invention relates to a micro device for solid phase extraction and more particularly provides a micro device which is configured to perform solid phase extraction by injecting a filler and a solvent and producing a uniform flow of the solvent. |
| US11065552B2 |
System for streaming databases serving real-time applications used through streaming interactive video
An apparatus includes one or more servers of a hosting service center operable to execute video game for one or more users remotely located from the hosting service center. The execution of the video game on the one or more servers produces uncompressed video of 3D animation. The one or more servers are operable to integrate live video with the video game such that the live video appears within the uncompressed video of 3D animation. The live video is received at a hosting service center from one or more client devices correspondingly associated with the one or more users. The uncompressed video 3D animation is generated, at least partially, using data streamed from a high-speed storage unit of the hosting service center coupled to the one or more servers. The high-speed storage unit is configured to load geometry for efficient loading and rendering of objects of the 3D animations. A compression unit compresses the uncompressed video 3D animation integrated with the live video, and compressed streaming interactive video being produced therefrom. An outbound routing network device coupled to the compression unit that transmits the compressed streaming interactive video over a packetized network to the one or more users. |
| US11065548B2 |
Statistical driven tournaments
The subject disclosure relates to systems and methods for ranking video game players based on performance statistics recorded during game-play. In some aspects, a process of the subject technology can include operations for receiving a first set of game-play attributes including two or more game-play statistics for measuring a first player's performance relative to a first game and a second game, receiving a second set of game-play attributes including two or more game-play statistics for measuring a second player's performance relative to the first game and the second game, and automatically ranking the first player and the second player based on the first set of game-play attributes and the second set of game-play attributes. Systems and computer-readable media are also provided. |
| US11065545B2 |
Use of machine learning to increase or decrease level of difficulty in beating video game opponent
Machine learning is used to determine one or more video game players' ability to defeat a non-player video game opponent, such as a boss. The level of difficulty in beating the video game opponent may then be increased or decreased based on the players' ability to beat the video game opponent. In some examples, another player may then opt in to the increased or decreased level of difficulty, or may choose to play the video game without the increased or decreased level of difficulty. |
| US11065544B2 |
Terminal device, program, method, and server apparatus
A terminal device includes a input interface, a display configured to display a virtual space of a game application, a memory, a sensor configured to detect position information about a player, and a processor configured to execute an instruction command stored in the memory to select a desired player character from one or a plurality of player characters in response to an instruction input received by the input interface, to select a desired candidate character from one or a plurality of candidate characters in response to the instruction input to be associated with the selected desired player character, and to display a movement of the selected desired player character on the display so that the selected desired player character moves in accordance with a movement of the selected desired candidate character in the virtual space. |
| US11065543B2 |
Processing device, program, and method
A processing device includes an input interface that accepts an operation input relating to an effect object from a player in a real world, the effect object being disposed in a virtual space displayed on a display, a memory that stores a parameter associated with one or a plurality of virtual objects, and a processor that executes an instruction command stored in the memory to vary a form of the effect object according to the operation input accepted by the input interface and to vary the parameter associated with at least the one or the plurality of virtual objects according to the form variation of the effect object. |
| US11065539B2 |
Method and system for sharing video game content
A video game sharing method and system enables users to share playable video game segments with users so that the users are able to view the video game segments or interactively play the video game segments. When shared, state information for the video game segments is included such that the users begin in the same position with the same relevant statistics. By enabling video game sharing, user enjoyment and video game popularity are increased. |
| US11065536B2 |
System and method for altering perception of virtual content in a virtual space
The disclosure relates to systems and methods for altering perception of virtual or game content in a virtual space based on one or more attribute levels. The perception of some virtual or game content may not be altered. Thus, the depiction of some content is altered while other content is not. A system may alter the depiction of game content based on attributes of an entity and/or based on which entity is to perceive the game content. The different depictions of game content may be provided to the same entity at different times and/or different perceptions of game content may be provided to different entities. Thus, a rich interface may be provided that differentially depicts game content based on attribute levels and/or the entity that is to perceive the game content. |
| US11065535B2 |
Information processing device, signal conversion method and program
Disclosed herein is an information processing device that provides an operation signal of an analog stick to a game, including: a conversion processing unit configured to convert a detection value obtained by detection of a movement of a controller into an analog stick signal; and an output processing unit configured to provide the analog stick signal obtained by the conversion to the game. The conversion processing unit includes a first calculation unit configured to calculate a first signal from a detected angular velocity, a second calculation unit configured to calculate a second signal according to a deviation amount between a direction in which the controller is directed and a reference direction, an addition unit configured to add the first signal and the second signal to generate a motion operation signal, and an analog stick signal generation unit configured to generate an analog stick signal from the motion operation signal. |
| US11065534B1 |
Thumbstick user input device and related methods
A thumbstick user input device may include a shaft carried by a housing and having an upper end extending outwardly beyond the housing for manipulation by the user's thumb and a lower end within the housing. Sensors may be carried by the housing to sense shaft movement. A first contact member may be within the housing, and a spring may be between the first contact member and the shaft to urge the first contact member and the shaft apart. A motor may be carried at a bottom of the housing and may have a rotatable output extending upwardly therefrom. A second contact member may be coupled to the rotatable output and in contact with the first contact member to be selectively moveable upward or downward based upon motor rotation to set a spring compression and thereby set a return-to-center bias for the shaft while being manipulated by the user's thumb. |
| US11065528B2 |
Thrust-responsive surface material for skis
A thrust-responsive structure for skis includes a plurality of retractable elements. Each retractable element includes a portion configured to move from an elevated position to a retracted position. Each retractable element further includes a first retention feature. The structure further comprises a matrix surrounding at least a subset of the plurality of retractable elements. The matrix is static relative to the plurality of retractable elements. The matrix includes a plurality of second retention features configured to captively engage the first retention features of the plurality of retractable elements. A position of each retractable element of the plurality of retractable elements, in the elevated position, is limited by contact between the first retention feature and the second retention feature. |
| US11065527B2 |
Reflective video display apparatus for interactive training and demonstration and methods of using same
A smart mirror can show live or recorded streaming video of an instructor performing a workout in a package that is attractive and unobtrusive enough to hang in a living room. The smart mirror includes a mirror surface with a fully reflecting section and a partially reflecting section. A display behind the partially reflecting section shows the video when the smart mirror is on and is almost invisible when the smart mirror is off. The smart mirror also has a speaker, a microphone, and a camera to enable a user to view the video content and interact with the instructor. The smart mirror may connect to the user's smart phone, a peripheral device (e.g., a Bluetooth speaker) to augment user experience, a biometric sensor to provide biometric data to assess user performance, and/or a network router to connect the smart mirror to a content provider, an instructor, and/or other users. |
| US11065523B2 |
Punching bag target suspended from suspension line and moveable along line until impeded by blocker
A punching bag kit includes a suspension line, a target having a fastening mechanism for suspending the target from the suspension line in a manner allowing the target to move along the suspension line, and a blocker positioned on the suspension line at a configurable distance from the target. The blocker is frictionally held in place on the suspension line at the configurable distance. Movement of the target along the suspension line is restricted upon the fastening mechanism of the target impacting the blocker. The blocker is physically larger than the fastening mechanism thus impeding travel of the fastening mechanism along the suspension line past the blocker. The blocker may have holes through which the suspension line passes, and a spring-loaded friction device may be mounted on the suspension line between two holes. The suspension line may travel around a user in plurality of segments suspending one or more targets. |
| US11065521B2 |
Punching-training device
A punching-training device includes a support body, having a seat end and an assembling end; a punching mechanism, including a plurality of punched members which are freely rotatable and separately mounted to the assembling end; wherein the assembling end includes small diameter shafts on which the punched members are rotatably mounted and are smaller than the seat end; the assembling end further includes a supporting rod, at least one interposed member and a stop portion, a first one of the small diameter shafts is connected between the supporting rod and the at least one interposed member, a second one of the small diameter shafts is arranged at an end of the at least one interposed member, and the stop portion is detachably connected at an end of the second one of the small diameter shafts. |
| US11065514B2 |
Iron-type golf club head with body wall apertures
An iron-type golf club head includes a body having a wall extending about an opening, a faceplate coupled to the body across the opening, first and second sets of apertures, and a fill material. The wall has an outer peripheral surface, a sole, a toe, a heel, a topline and a rear wall portion extending from the heel to the toe. The wall and the faceplate define a rearward-facing back cavity, and the sole, the rear wall portion and the faceplate define a lower cavity that is continuous with the back cavity. The first and second sets of apertures extend through the wall from the peripheral outer surface to, and are continuous with, the lower cavity. The first and second sets of apertures extend about first and second planes, respectively. The fill material substantially fills the lower cavity and the first and second sets of apertures. |
| US11065505B2 |
Bicycle trainer and method of its operation
Method for operating a bicycle trainer, and such a bicycle trainer comprising a stand with a seat, handlebars and rotatable pedals, or such a bicycle trainer comprising a stand for mounting a bicycle frame with a seat, handlebars and rotatable pedals, wherein the stand incorporates an electronically variable brake acting directly or indirectly on the rotatable pedals with a braking resistance that depends on a computer-controlled predetermined setting, wherein the pre-determined setting is variable and wherein said setting depends on selected parameters to reflect a simulated surface condition of a road. |
| US11065501B2 |
Single-arm workout body conditioning machine
An exercise machine allows a user to perform a variety of resistance exercises with adjustable resistance levels. The machine is made up of an arm, a user platform, a horizontal base, an adjustable counterweight arrangement, a pull rod, a drive chain system, sprockets, shafts, adjustable fan, a slip bearing, a recoiler, a plurality of wheels, a drive chain system housing, a user back support, a user cable grip, and a circuit-breaking sensitive rubber mat. When the arm is moved upwards (by a user) the pull rod attached to a drive chain initiates the drive chain system rotation. The drive chain system rotation includes an adjustable weight fan that creates resistance to the arm's upper movement through inertia. The adjustable counterweight arrangement determines the arm drop speed and the arrangement has multiple positions. Other variants include a plurality of electronic encoders. |
| US11065494B1 |
Exercising device with rehabilitation function
An exercising device includes a main frame, a seat, a backrest, a swing unit, a magnetically controlled damper, and an electronic control panel. The swing unit is swingably mounted on the upright of the main frame. The swing unit includes two handlebars extending from the upright to the seat respectively. The magnetically controlled damper is pivotally mounted between the swing unit and the main frame. The electronic control panel is electrically connected with the magnetically controlled damper. When the two handlebars are moved by the user, the magnetically controlled damper provides a damping force to retard movement of the two handlebars. The electronic control panel controls and regulates the resistance of the magnetically controlled damper. |
| US11065493B2 |
Plyometric fitness platform with constrained adjustability
Disclosed are systems and methods for plyometric fitness systems that facilitate constrained multi-directional movements. By utilizing a variety of constrained elastic resistance cords in conjunction with plyometric platform stations and performance patterns, this system enhances dimension, capability and variety to conventional agility and jumping drills. The disclosed plyometric platforms are designed for contrast training, or resistance loaded and unloaded exercises. This allows the muscles to adapt to the loaded exercises and then apply the “learned” movement to the unloaded exercise. This directly reinforces the movement and muscle exertion needed to perform powerful movements thereby enhancing athletic performance. |
| US11065490B2 |
Method for addition of fire suppression additive to base foam solutions
A method of proportioning a finished foam at or near a hazard comprising proportioning and delivering a first finished foam to the hazard, determining if the first finished foam extinguishes or suppresses the hazard, if not, selecting an amount of a fluorinated additive, and proportioning a foam solution including the selected amount of the fluorinated additive to form a fluorinated finished foam. A foam injection system is also disclosed. |
| US11065487B2 |
Dry sprinkler assemblies
A dry sprinkler assembly capable of providing fire suppression protection, including early suppression fast response protection and storage protection of a commodity having a nominal storage height of at least 20 feet beneath a ceiling of with a maximum nominal 40 foot ceiling height. The dry sprinkler assembly includes an internal passageway and an outlet defining a nominal K-factor of at least 16.8 GPM/PSI1′2. Embodiments of the sprinkler assembly include a deflector having a plurality of tines radially disposed about a central portion to define slots therebetween. Embodiments of the deflector define a non-planar deflecting member and a member with a non-circular perimeter. Installation of the sprinkler assembly provides for a insulation sealing assembly having a insulation ring, planar insert member and a surrounding housing. |
| US11065481B1 |
Safety harness motion detector systems and methods for use
Systems and methods for monitoring elevations of a set of workers at a job site include reference devices for capturing barometric pressures at different installation elevations on a structure and portable barometric pressure sensors carried by the workers. An atmospheric pressure offset may be calculated using the reference barometric pressures and installation elevations. The atmospheric pressure offset may be applied to atmospheric pressure measurements captured by the barometric pressure sensors carried by the workers to determine worker elevations. The worker elevations may be converted to corresponding floors of the structure. |
| US11065480B2 |
PPE with rotating assembly providing multiple face covers
A personal protective device (PPE), which can include a face cover assembly and a bodysuit configured to be worn by a human user. The device protects users against airborne aerosol particles containing viruses or other infectious agents while enabling improved flexibility relative to prior art designs. The device includes a helmet-like” rotating face cover assembly that fits over the user's head and attaches to a collar on the biohazard bodysuit. This rotating face cover assembly has a plurality of different mask sides, each with differing geometries or other properties. The device enables a user to can rotate the cover and select a given mask side that best meets that user's needs. The different mask sides can accommodate different facial geometries, eyewear types, and use cases. |
| US11065478B2 |
Portable containment device
Portable containment device having a chamber which further includes a first end, a second end, and a vertical wall, wherein a filter is arranged at the second end to entrap airborne particles emitted into an opening formed at the first end of the portable containment device. |
| US11065477B2 |
Fall-protection apparatus with braking system
A fall-protection apparatus with a friction-braking system comprising a handle that is disconnectably connected to a braking cam so that when the handle is moved from a braking position to a non-braking position the braking cam is pivotally moved from a braking configuration to a non-braking configuration, and so that when the handle is moved to a disconnecting position the connection between the handle and the braking cam is disconnected. |
| US11065472B2 |
System and method for correcting position errors of a multi-leaf collimator
Methods and systems for correcting position errors for a multi-leaf collimator (MLC) are provided. A method may include determining a first position for each of the plurality of leaves. The information associated with the first position may include a first movement direction and a first angle. A movement of the each of the plurality of leaves along the first movement direction may be configured to move toward or away from a center of the radiation field. The method may also include determining an offset value associated with the first position based on the first angle and the first movement direction; and determining a target position of the each of the plurality of leaves based on the offset value. |
| US11065465B2 |
Defibrillator cover
A defibrillator and a cover adhered to the defibrillator is provided. The defibrillator includes: a case; a handle at an upper surface of the case; a display panel at a front face of the case; and a plurality of buttons at the front face of the case. The cover covers the display panel and at least some of the buttons, and the cover includes a flexible plastic film. |
| US11065460B2 |
Battery assembly for medical device
In some examples, a battery assembly for an implantable medical device may include an electrode stack comprising a plurality of electrode plates. The plurality of electrode plates may comprise a first electrode plate including a first tab extending from the first electrode plate and a second electrode plate including a second tab extending from the second electrode plate, an alignment member extending through the first tab and the second tab, and a weld on a side of the electrode stack extending from the first tab to the second tab, wherein the weld penetrates into the alignment member. |
| US11065457B2 |
Method for waking up an implantable medical device from a dormant state, implantable medical device, and system comprising such an implantable medical device and an external device
A method for waking up an implantable medical device from a dormant state, an implantable medical device, and a system that includes such an implantable medical device and an external device. The implantable medical device is woken up from a dormant state by sending a modulated wakeup signal via a wireless link from an external device. The modulated wakeup signal is demodulated by way of a demodulator circuitry of the implantable medical device so as to produce a demodulated wakeup signal. The demodulator circuitry is permanently ready for operation. An awake state of the implantable medical device is then activated in response to the demodulated wakeup signal. |
| US11065455B2 |
Resonance tuning module for implantable devices and leads
An implantable medical assist device includes a medical device. The medical device has a housing and electronics contained therein. A lead provides an electrical path to or from the electronics within the medical device. A resonance tuning module is located in the housing and is connected to the lead. The resonance tuning module includes a control circuit for determining a resonant frequency of the implantable medical assist device and an adjustable impedance circuit to change the combined resonant frequency of the medical device and lead. |
| US11065452B2 |
Ventricular tachycardia storm analysis and ventricular tachycardia storm intervention method and system
Methods, devices and program products are provided. The method is under control of one or more processors within an implantable medical device (IMD), obtains cardiac signals that comprise candidate episodes over a period of time and updates an episode count and episode density clock based on the candidate episodes within the period of time. Further, the method determines whether the candidate episodes are indicative of a ventricular storm arrhythmia based on the episode count and episode density clock, identifies a storm origin characteristic of interest preceding onset of the candidate episodes and directs the IMD to perform a storm intervention based on the identifying operation. |
| US11065450B1 |
Neuromodulation system and method with feedback optimized electrical field generation
A neuromodulation system and method with feedback optimized electrical field generation for stimulating target tissue of a patient to treat neurological and non-neurological conditions. The system generally includes implantable electrodes, implantable sensors, an implantable or external electrical signal generator, and an implantable or external controller. The controller controls the electrical signal generator to generate electrical noise stimulation signals that are delivered to the target tissue via the electrodes and that produce an optimized electric field having maximized voltage with low current density. The sensors produce temperature and impedance data for the target tissue and the controller automatically responds to values of the sensor data that indicate potential damage to the target tissue to reduce the strength of the electric field. |
| US11065448B2 |
System and method for ocular microcurrent stimulation therapy
Devices and methods to deliver microcurrent stimulation therapy to the human body, when connected to a micro-stimulation current-generating apparatus. The method of applying microcurrent stimulation therapy to key points around the eye for treatment of problems such as macular degeneration, retinitis pigmentosa, glaucoma, optic neuritis and other eye-related or nerve-related conditions, as well as other diseases, such as Bell's Palsy, requiring localized stimulation to the eyes and/or on other body parts. |
| US11065443B2 |
Respiratory rectification
A means for treating breathing disorders by stimulating respiratory muscles or nerves to entrain respiratory systems while leaving respiratory drive intact. Embodiments of the invention employ frequency analysis to determine if appropriate stimulation energy is being applied. |
| US11065440B2 |
Hearing assistance device comprising an implantable part
A hearing assistance device comprises an implantable part for electrically stimulating an auditory nerve of a user. The implanted part comprises a) a current source generator; and b) an electrode array configured to be located inside one of the cochlear scala or adjacent to the auditory nerve. The hearing assistance device is configured to produce a time-varying waveform delivered by the current source generator, the time-varying waveform comprising a positively sloping positive pulse. This has the advantages of providing a smaller spatial spread of neurons being discharged by electric stimuli from a given electrode. The invention may e.g. be used in cochlear implant hearing assistance devices. |
| US11065438B2 |
Systems and methods for transseptal delivery of percutaneous ventricular assist devices and other non-guidewire based transvascular therapeutic devices
A system and method used to deliver a percutaneous ventricular assist device (pVAD) or other cardiac therapeutic device to a site within the heart, such as a site at the aortic valve. A flexible device is percutaneously introduced into a vasculature of a patient and positioned to run from a femoral vein, through the heart via a transseptal puncture, and to a femoral artery. The venous-side end of the flexible device is withdrawn out the venous vasculature superior to the heart, and a pVAD is secured to the flexible device. The pVAD is pushed in a distal direction while the arterial-side end of the flexible device is pulled in the proximal direction to advance the pVAD to the target site. A left ventricle redirector aids in orienting the pVAD and preventing migration of the flexible member towards delicate structures of the heart during advancement of the pVAD. |
| US11065436B2 |
Communication methods and architecture for heart treatment systems
The present invention generally relates to heart treatment systems. In some aspects, methods and systems are provided for facilitating communication between implanted devices. For example, an implantable cardiac rhythm management device may be configured to communicate with an implantable blood pump. The implantable cardiac rhythm management device may deliver heart stimulation rate information in addition to information associated with any detected abnormalities in heart function. In response, the pump may be configured to adjust pumping by the pump to better accommodate a patient's particular needs. |
| US11065435B2 |
Blood pump and blood pump adjusting method
A blood pump includes a blood supply mechanism; a motor having a stator, a rotor and a shaft; a base body; a casing; a fixed side slide member having a first slide surface and fixed to the base body; and a rotary side slide member. A second insertion hole allows the shaft to pass therethrough is in the rotary side slide member. The shaft is fitted into the second insertion hole between the fixed side slide member and the blood supply mechanism. The second slide surface is slidable on the first slide surface in contact with the first slide surface by rotating together with the blood supply mechanism and the shaft A center of the core is at a position more to a +z direction side than a center (CM) of a permanent magnet. |
| US11065434B2 |
Blood pump with impeller rinse operation
A method of operating an implantable blood pump having a first stator, a second stator, and an impeller movably disposed there between. The method includes applying a first voltage waveform at first phase to the first stator to generate a magnetic field to rotate the impeller. A second voltage waveform is applied at a second phase shifted from the first phase to the second stator to rotate the impeller, the second voltage waveform is asymmetric to the first voltage waveform. |
| US11065432B2 |
Apparatus and methods of dispensing fluid intravenously and flushing lines of intravenous fluid administration systems
Apparatus and methods of dispensing fluid intravenously to a subject, and of flushing a line of an intravenous fluid administration apparatus, are provided. The apparatus may include a chamber including a plurality of connector ports and be configured to operate in fluid communication with an upstream source via a first connector port and, during operation, pass therethrough to downstream tubing, under a first pressure condition, first fluid from the upstream source via a second connector port. A third connector port may be configured to connect to an end of tubing or a valve connector such that, during operation, the chamber is configured to, under a second, higher pressure condition, pass therethrough to the downstream tubing a second fluid from a second fluid source via the third and second connector ports, prevent first fluid flow into the downstream tubing, and prevent second fluid flow through the first connector port. |
| US11065426B2 |
Implantable device with intravesical tolerability and methods of treatment
Intravesical devices are provided that are wholly deployable within the bladder of a patient in need of treatment and are well tolerated by the patient. The device may include an elastic body having a retention shape having (i) dimensions that provide intravesical mobility and that prevent voiding of the medical device through the urethra, and (ii) dimensions, buoyancy, or both, that exclude the medical device from entering the orifices of the ureters. The elastic body may exert a maximum acting force less than 1N when compressed to a shape with a maximum dimension in any dimension of 3 cm. The device may include a drug for controlled release within the bladder, for treatment of the bladder or a regional tissue. Methods of treatment are also provided that include selecting a patient in need of treatment in the bladder where tolerability of the treatment is a primary concern. |
| US11065425B2 |
Cerebrospinal fluid purification system
The present invention provides methods and systems for conditioning cerebrospinal fluid (CSF) by removing target compounds from CSF. The systems provide for a catheter flow path and exchange of a majority volume portion of CSF in the CSF space. The removal and/or delivery of specific compounds can be tailored to the pathology of the specific disease. The removal is targeted and specific, for example, through the use of specific size-exclusion thresholds, antibodies against specific toxins, and other chromatographic techniques, as well as delivery and/or removal of targeted therapeutic agents. |
| US11065423B2 |
Balloon catheter
A balloon catheter includes an inner shaft with a distal variant portion and a proximal variant portion. A bulged portion is provided at the distal end of a reinforcement member, and the bulged portion is configured to move in an axial direction between the distal variant portion and the proximal variant portion. Thus, the balloon catheter may smoothly pass through a curved blood vessel with improved kink resistance of the reinforcement member. |
| US11065419B2 |
Catheter delivery devices, systems, and methods
A system can include a handle and a needle fixedly secured to the handle. The needle can include a distal tip that can be inserted through a sidewall of a vessel of a patient. The system can further include a catheter that defines a lumen through which the needle extends and includes an engagement surface at an interior thereof. A stiffener can be positioned within the lumen of the catheter at an exterior of the needle and can include an engagement surface that can press distally on the engagement surface of the catheter to advance the catheter distally over the needle and through a lumen of the vessel when the stiffener is advanced distally over the needle. The system can further include a stiffener hub attached to the stiffener, the stiffener hub being movably coupled with the handle so as to translate relative thereto. The stiffener hub can be configured to move distally relative to the handle from a retracted position to a deployed position to advance the stiffener and the catheter over the needle and to a target depth within the lumen of the vessel as the handle is held stationary relative to the vessel. |
| US11065415B2 |
Gas delivery device and system for use in magnetic resonance imaging
The present invention relates to a device and method of delivering inhaled Nitric Oxide (iNO) to a patient situated in a Magnetic Resonance Imaging (MRI) suite. |
| US11065414B2 |
Component for medical circuit
A medical tube has a tube wall defining a passageway for transportation of gases and further has a first end and a second end. At least one end of the medical tube comprises one or more of a pre-formed pneumatic port component, a pre-formed electrical port component, and a pre-formed sensor port component. A cuff is over-moulded about and thereby connects the pneumatic port component, the electrical port component, and/or the sensor port component and at least a portion of the tube end. |
| US11065411B2 |
Customized sealing member from blank
A customized sealing member is for a customized mask of a pressure support system. The steps to manufacture the customized sealing member include generating surface geometry data of a face of a patient, the surface geometry data corresponding to and representing a surface geometry of the face of the patient; generating customization data using the surface geometry data, the customization data representing how a seal blank should be modified for the patient; and customizing the seal blank using the customization data such that the customized seal blank is shaped according to the customization data. |
| US11065408B2 |
Method for delivery of breathing gas to a patient and system for performing same
A method for controlling the delivery of a breathing gas to a patient. The method comprises: delivering a flow of breathing gas to a patient, the breathing gas having a breathing gas flowrate and a fraction of inspired oxygen; measuring an oxygen saturation level of the patient; determining a respiratory rate of the patient; automatically adjusting the fraction of inspired oxygen of the breathing gas based on the measured oxygen saturation level of the patient and a breathing gas flowrate set-point; and automatically adjusting the breathing gas flowrate set-point based on the determined respiratory rate of the patient. |
| US11065406B2 |
Interface comprising a rolling nasal bridge portion
An interface for positive pressure therapy includes a mask assembly, a headgear assembly and a connection port assembly. The mask assembly comprises a seal member that has an upper portion movably connected to an integrated lower portion, wherein the upper portion rolls during hinging movement of the upper portion relative to the lower portion. The headgear assembly allows connection to the mask assembly in a direction substantially normal to a direction of strap tension. The connection port assembly includes a swivel elbow with a valve member that controls flow through a port that opens toward the user. |
| US11065402B2 |
Aromatherapy vaporization device
A vaporization device includes a housing, a fluid pathway extending through the housing, a heating chamber with a heating element proximate a first housing end, a control circuit and a battery disposed within the housing. The heating chamber is in fluid communication with the fluid pathway. The first chamber end is open and the second chamber end includes a closed end with one or more vents. The heating element is operable to generate heat at a predetermined vaporization temperature. The control circuit has a switch operable to control a flow of current from the battery to the heating element. In use, the predetermined vaporization temperature is sufficient to vaporize phyto material in contact with the heat at the predetermined vaporization temperature to emit a vapor. Inhaling from the second housing end draws mixed vapor and air through the fluid pathway. |
| US11065400B2 |
Aerosol forming device for use in inhalation therapy
Inhalation delivery of aerosols containing small particles is described. Specifically, it relates to a device that forms drug containing aerosols for use in inhalation therapy. In a device aspect of the present disclosure, a device for delivering drug containing aerosols for inhalation therapy is provided. The device includes a housing and an airway that has a gas/vapor mixing airway. The airway further includes a subassembly, which has a metallic substrate coated on its surface with a composition comprising a drug. |
| US11065391B2 |
Automatic injection device with variable dosing
A medication injection device comprising a medication container to contain medication; a connector provided with a blocking feature; a push rod having a plurality of teeth disposed along the length, and a spring biasing against the push rod to move proximally. The spring can be compression spring, extension spring, torsion spring, or constant force spring. By enabling or disabling engagement between the blocking feature on the connector and the tooth on the push rod, the push rod is either prevented from moving distally or allowed to move distally. The medication is drawn into the medication container when the push rod moves proximally and the medication is dispensed out of the medication container when the push rod moves distally. |
| US11065389B2 |
Assembly for a drug delivery device
An assembly for a drug delivery device is presented. The assembly comprises a housing and a piston rod having a longitudinal axis, a distal end and a proximal end. The piston rod further comprises a piston rod interaction feature, and a piston rod guide being movable with respect to the piston rod, the piston rod guide further comprising a guide interaction feature corresponding to the piston rod interaction feature, the piston rod guide being movable with respect to the piston rod to switch between a first state and a second state of the assembly, the second state being different from the first state. The assembly is configured such that, in a first state of the assembly, the piston rod guide is in a first axial position relative to the piston rod in which the piston rod interaction feature is arranged to interact with the guide interaction feature to prevent proximal movement of the piston rod with respect to the housing, and wherein, in a second state of the assembly being different from the first state, the piston rod guide is in a second axial position relative to the piston rod, the second axial position being different from the first axial position, wherein, in the second axial position, the piston rod interaction feature and the guide interaction feature are arranged such that proximal movement of the piston rod with respect to the housing is allowed. |
| US11065376B2 |
Plasmapheresis centrifuge bowl
A plasmapheresis bowl for the separation and collection of plasma includes a core and a feed tube that increase the bowl efficiency and reduce foaming within the plasma. The core may have a cylindrical body and a ledge located within the interior of the core. The ledge extends radially inward from the core and defines, at least partially, a collection chamber within the plasmapheresis bowl. The core also has ribs that extend above the top of core body and create flow paths that allow fluid to enter the interior of the cylindrical body and collection chamber. The feed tube has a flow path extending through it that fluidly connects an inlet port on the plasmapheresis centrifuge. A first skirt member on the feed tube has a smooth angled surface that helps to reduce foaming. |
| US11065372B2 |
Needle system restrictor
A needle system a handle and a needle slider partially positioned in the handle. The needle slider has an aspiration port at a proximal end of the needle slider. A needle connected to and extending away from the needle slider. A restrictor is disposed in the aspiration port of the needle slider. The restrictor is configured to inhibit passage of a sample through the aspiration port. |
| US11065367B2 |
Highly hydrophobic antifouling coatings for implantable medical devices
Antibacterial coatings and methods of making the antibacterial coatings are described herein. In particular, a method for forming an organocatalyzed polythioether coating is provided in which a first solution including a bis-silylated dithiol and a fluoroarene is prepared. A second solution including an organocatalyst is prepared. The first solution and the second solution are mixed to form a mixed solution. The mixed solution is applied to a substrate, and the substrate is cured. |
| US11065361B2 |
Water-containing hydrogels for dressing wounds
The invention relates to water-containing hydrogels for dressing wounds, comprising a polyurethane-polyurea copolymer having a polyvalent alcohol, except propylene glycol. |
| US11065359B2 |
Deodorization module and storage device including deodorization module
A deodorization module and a storage device including the deodorization module. A deodorization module includes: a housing; a suction opening formed on the lower surface of the housing to allow external air to be suctioned therethrough; a fan disposed at the suction opening to suction the air; a discharge opening for discharging the air, which has been suctioned by the fan, to the outside of the housing; a photocatalytic bar disposed between the fan and the discharge opening; and a light source module, which includes a light source substrate and an ultraviolet light source and irradiates an ultraviolet ray to the photocatalytic bar. |
| US11065356B2 |
Magnetic separation using nanoparticles
Nanoparticles as described herein are configured to bind to bacterial contaminants, such as Gram positive bacteria, Gram negative bacteria, and endotoxins. The nanoparticles include a core comprising a magnetic material; and a plurality of ligands attached to the core. The ligands include, for example, bis(dipicolylamine) (“DPA”) coordinated with a metal ion, e.g., Zn2+ or Cu2+, to form, e.g., bis-Zn-DPA or bis-Cu-DPA, which can bind to the bacterial contaminants. The nanoparticles can be included in compositions for use in methods and systems to separate bacterial contaminants from liquids, such as liquids, such as blood, e.g., whole or diluted blood, buffer solutions, albumin solutions, beverages for human and/or animal consumption, e.g., drinking water, liquid medications for humans and/or animals, or other liquids. |
| US11065355B2 |
Device for monitoring efficacy of a decontamination process comprising a bacteria cell and method of using
A device for monitoring the effectiveness of a decontamination process, the device including a bacteria cell as the indicator test organism and optionally a substrate, where the indicator test organism may include a Mycobacteria terrae cell, and methods of using the monitoring device to evaluate the efficacy of a decontamination process. |
| US11065354B2 |
Post-steam sterilization moisture-indicating articles
Post-steam sterilization wet pack indicators are described. The indicators generally comprise a moisture-impermeable layer having a first surface and a moisture-indicating layer comprising a reversible colorimetric steam-sterilization-compatible moisture-indicating medium. The moisture-indicating layer is disposed on or near the first surface of the moisture-impermeable layer. The area of the moisture-indicating layer is dimensionally smaller than the moisture-impermeable layer such that the edges of the moisture-impermeable layer extend beyond the edges of the moisture-indicating layer. Articles and packages comprising wet pack indicators are also described. |
| US11065350B2 |
HSP90-targeted inflammation and infection imaging and therapy
The present invention provides new methods for inflammation and infection imaging and related medical applications thereof. In some embodiments, the present invention provides a method for the diagnosis of inflammation and/or infection. In some embodiments, the present invention provides a method for the treatment or prevention of inflammation and/or infection. In some embodiments, the present invention provides methods for monitoring the effect of inflammation and/or infection treatment, and/or methods for monitoring an inflammation and/or infection treatment regimen. In some embodiments, the present invention provides a method for selecting subjects for an inflammation and/or infection treatment. In some embodiments, the present invention provides a method for determining the dosage of a drug for the treatment of inflammation and/or infection. |
| US11065348B2 |
Apparatus and methods for making recombinant protein-stabilized monodisperse microbubbles
A microfluidic device for generating microbubbles includes a substrate and a microfluidic channel embedded in the substrate. The microfluidic channel includes a plurality of fluid inlets, at least one bubble formation outlet having a nozzle with an adjustable diameter, and a flow focusing junction in fluid communication with the plurality of fluid inlets and the bubble formation outlet. A method for mass producing monodisperse microbubbles with a microfluidic device includes supplying a flow of dispersed phase fluid into a first fluid inlet of a microfluidic channel, supplying a flow of continuous phase fluid into a second fluid inlet of the microfluidic channel, and adjusting a diameter of a nozzle to obtain a plurality of monodisperse microbubbles having a specified diameter. |
| US11065338B2 |
Polysaccharide therapeutic conjugates
A composition includes a polysaccharide at least one retinoid linked to at least one monosaccharide subunit of the polysaccharide with a covalent linkage. The linkage being degradable by hydrolysis during digestion of the composition to provide controlled, delayed, and/or sustained delivery of the at least one retinoid upon enteral administration of the composition to a subject. |
| US11065334B2 |
Boron-10 containing biocompatible nanostructures
A method comprises providing a plurality of nanostructures comprising a base material. The plurality of nanostructures are exposed to a first material at a first deposition temperature. The plurality of nanoparticles are exposed to a second material at a second deposition temperature, and exposed to a Boron-10 (10B) containing material at a third deposition temperature so as to form a 10B-metal oxide based composite nanostructure. |
| US11065332B2 |
Combination therapy of immunotoxin and checkpoint inhibitor
Regional, tumor-targeted, cytotoxic therapy, such as D2C7-immunotoxin (D2C7-IT), not only specifically target and destroy tumor cells, but in the process initiate immune events that promote an in situ vaccine effect. The antitumor effects are amplified by immune checkpoint blockade which engenders a long-term systemic immune response that effectively eliminates all tumor cells. |
| US11065327B2 |
Human rotavirus strains and vaccines
A vaccine composition and method of vaccination are provided useful for immunizing a subject against a rotavirus. The vaccines include rotavirus strains CDC-9 and CDC-66, fragments thereof, homologues thereof, or combinations thereof. Inventive vaccines may include a fragment of CDC-9, CDC-66, homologues thereof, or combinations thereof. Methods of inducing an immunological response are provided by administering an inventive vaccine. |
| US11065326B2 |
Live-attenuated vaccine having mutations in viral polymerase for the treatment and prevention of canine influenza virus
The present invention relates to compositions and methods for the treatment and prevention of canine influenza virus (CIV) and CIV-related pathology. The present invention is based in part upon the discovery that various mutations in segment 1 and segment 2 of the CIV genome, thereby encoding mutant PB2 and PB1 protein, render the virus to be temperature-sensitive. |
| US11065324B2 |
Combination vaccine for swine
The present invention relates to a combination vaccine for swine, comprising non-replicating antigen from porcine circovirus type 2 (PCV2), and live porcine reproductive and respiratory syndrome virus (PRRSV); the combination vaccine is formulated as an oil-in-water emulsion, and is adjuvated with squalane and vitamin E-acetate. This combination vaccine was found to be immunologically effective against all pathogens: PCV2, and PRRSV. |
| US11065322B2 |
Bacterial vaccine components and uses thereof
Agents, compositions, methods and kits useful for the treatment and diagnosis of Staphylococcal intramammary infection are disclosed. The agents, compositions, methods and kits are derived from genes expressed during Staphylococcal intramammary infection, and more particularly genes SACOL0442, based on the gene nomenclature from the Staphylococcus aureus COL (SACOL) genome. |
| US11065320B2 |
Prime target
The invention relates to a kit comprising at least a first composition and a second composition, each said first and second compositions comprising at least one epitope of a liver disease antigen, wherein said epitope is a CD8+T cell epitope, for use in induction of an immune response in the liver of a mammalian subject by administration of said first composition by intramuscular (i.m.), subcutaneous (s.c.), intradermal (i.d.) or aerosol route, and administration of said second composition by intravenous (i.v.) or subcutaneous (s.c.) route, characterised in that said first and second compositions are administered by different routes. The invention also relates to uses, methods and treatments. |
| US11065317B2 |
Heat shock protein-binding peptide compositions and methods of use thereof
Provided are polypeptides and compositions comprising novel HSP-binding peptides. Such polypeptides and compositions are particularly useful as immunotherapeutics (e.g., cancer vaccines). Also provided are methods of inducing a cellular immune response using such polypeptides and compositions, methods of treating a disease using such polypeptides and compositions, kits comprising such polypeptides and compositions, and methods of making such compositions. |
| US11065313B2 |
Modified yeast-brachyury immunotherapeutic compositions
Disclosed are improved yeast-based immunotherapeutic compositions comprising modified Brachyury antigens, and methods for the prevention and/or treatment of cancers characterized by the expression or overexpression of Brachyury. |
| US11065305B2 |
Compositions in the form of an injectable aqueous solution including at least human insulin A21G and a glucagon suppressor with prandial action
A composition in the form of an injectable aqueous solution, with pH from 3.5 to 4.4, including at least human insulin A21G and at least one glucagon suppressor with prandial action. In an embodiment, the glucagon suppressor with prandial action is selected from an amylin analog or an amylin receptor agonist or a GLP-1 analog or a GLP-1 receptor agonist (GLP-1 RA). In an embodiment, the glucagon suppressor with prandial action is an amylin analog or an amylin receptor agonist. In an embodiment, the glucagon suppressor peptide with prandial action is pramlintide. Also, a method for obtaining human insulin A21G, includes at least one step of reacting human insulin A21G, B31R, B32R (insulin glargine) with rat carboxypeptidase B at an insulin/carboxypeptidase ratio from 500 to 2000, at a pH from 7.5 to 8.5 and a temperature from 20 to 30° C. for 10 to 20 hours. |
| US11065303B2 |
Compositions and methods for treating pulmonary hypertension
In some aspects, the disclosure relates to GDF/BMP antagonists and methods of using GDF/BMP antagonists to treat, prevent, or reduce the progression rate and/or severity of pulmonary hypertension (PH), particularly treating, preventing or reducing the progression rate and/or severity of one or more PH-associated complications. The disclosure also provides methods of using a GDF/BMP antagonist to treat, prevent, or reduce the progression rate and/or severity of a variety of conditions including, but not limited to, pulmonary vascular remodeling, pulmonary fibrosis, and right ventricular hypertrophy. The disclosure further provides methods of using a GDF/BMP antagonist to reduce right ventricular systolic pressure in a subject in need thereof. |
| US11065300B2 |
Immunomodulator for hypersensitivity reaction to house dust mite-derived allergen
The present invention relates to an immunomodulator for the prevention or treatment of an allergic disease caused by house dust mite-derived allergens. Particularly, the present invention provides an immunomodulatory pharmaceutical composition comprising as an effective ingredient a bacteria extracellular vesicle containing an allergens derived from North American house dust mite or European house dust mite, and a preparation method therefor. |
| US11065295B1 |
Compositions and methods for nutritional supplements
Compositions and methods are presented in which a plurality of chemically distinct polyphenols inhibit multiple enzymes in pathways associated with health and healthy ageing. Preferred compositions are derived from colored plant materials that are commonly found in the Mediterranean diet and provide the biochemical basis for the health benefits of the Mediterranean diet. Notably, the enzyme inhibition observed with the combined polyphenols was synergistic with respect to not one but a significant number of enzymes in the pathways associated with health and healthy ageing, thus providing an amplified desirable effect. |
| US11065294B2 |
Composition including oriental medicine to treat neoplastic disease
Provided is a composition for enhancing effects of an anticancer agent using an oriental medicine, jaeumganghwa-tang, bojungikgi-tang, or yukmijihwang-tang. More particularly, provided is a composition for treating a neoplastic disease by administering an anticancer agent into an individual, and administering an oriental medicine into the individual within 30 minutes. The composition remarkably reduces side effects occurring when the anticancer agent is administered alone by co-administration of the oriental medicine, reduces cytotoxicity, and has higher anticancer activity than that when the anticancer agent is administered alone. |
| US11065291B2 |
Traditional Chinese medicine composition for treating tumours, preparation method therefor and use thereof
Disclosed are a traditional Chinese medicine composition for treating tumours and a preparation method therefor, wherein the composition is prepared from Sophora flavescens, wild Chrysanthemum flower, honeysuckle, mint, Poria cocos, Atractylodes lancea, cinnamon, clove, Astragalus, Ganoderma lucidum, Ligusticum striatum, Aucklandia root and Radix glycyrrhizae. The traditional Chinese medicine composition has an anti-tumour effect. |
| US11065290B2 |
Topical composition
The invention discloses a therapeutic topical composition, includes an extract of Galenia Africana having anti-microbial and anti-oxidant action. The composition includes rooibos and/or an extract from rooibos tea plant. The composition is adapted for regenerating skin, stimulating cyto-keratin production, treating human external fungal infections and/or conditions, human skin bacterial conditions, psoriasis, psoriasis plaque, dandruff, acne, bacterial acnes, eczema, athletes' foot, nappy rash, baby rash and/or lesions and/or being used for anti-septic wound treatment, and/or treating Propionibacterium acnes and/or staphylococcus epidermidis. |
| US11065289B1 |
Substance and method for the treatment of poxvirus
A substance for poxvirus molluscum infection treatment that includes a mixture of Anacardium occidentale seeds and sunflower oil is disclosed. The mixture is obtained by the washing, drying, and grinding of at least seven Anacardium occidentale seeds. The grinded seeds are then mixed in with at least one cup of sunflower oil. The mixture is then heated under a low temperature for a duration of at least ten minutes until the seeds are in a liquid or semi-liquid state. The temperature is then raised when the mixture begins to change color. The temperature is then lowered once the mixture ceases to produce smoke. The mixture is then strained and poured into sterile bottles which are wrapped in aluminum foil. When applied to a user, the mixture is then placed on a patch which is then placed on an infected area of a user's body. |
| US11065288B2 |
Neuron activator
The present disclosure provides a neuron activator that activates neurons. The neuron activator includes at least one selected from the group consisting of a dopamine production promotor that promotes dopamine production of the neurons, a neuron extension promotor that promotes extension of the neurons, and an amyloid β resistance enhancer that enhances resistance of the neurons against amyloid β. The neuron activator includes 6-methylsulfinylhexyl isothiocyanates or glycosides thereof, and at least one selected from the group consisting of unsaturated fatty acid and polyphenol. |
| US11065286B2 |
High mobility group box I mutant
Provided herein are oncolytic vaccinia viruses which have been modified to contain an exogenous nucleic acid that codes for a variant HMGB1 protein. Such vaccinia viruses modified to contain nucleic acid encoding variant HMGB1 and that express a variant HMGB1 or a fragment thereof can achieve a synergistic effect in combination with chemotherapy. Methods of using oncolytic vaccinia viruses modified to contain an exogenous nucleic acid that codes for a variant HMGB1 protein, in the treatment of various cancers, are also provided. |
| US11065285B2 |
Biomarkers and combination therapies using oncolytic virus and immunomodulation
The invention disclosed herein describes biomarkers useful for prognosis, selection and monitoring of oncolytic virus therapy for patients with various types of cancer. In particular, the present invention provides identification of proteins whose expression patterns are strongly predictive of the outcome of oncolytic virus therapy in a patient with cancer. The present invention provides a method for identifying and selecting cancer patients who are likely to be non-responsive to onocolytic virus therapy. These patients can be co-administered an agent that stimulates a cell-mediated immune response in the patient with the oncolytic virus or can be administered a therapy other than oncolytic virus therapy. |
| US11065283B2 |
Immunomodulatory compositions and methods of use thereof
The present disclosure provides immunomodulatory compositions comprising live Caulobacter crescentus (CC). Immunomodulatory compositions of the present disclosure are useful for modulating an immune response in an individual. The present disclosure thus provides methods of modulating an immune response in an individual, involving administering an immunomodulatory composition comprising live CC to the individual. |
| US11065281B2 |
Composition for preventing or treating ischemic enteritis containing DNA fragment mixture isolated from sperm or testis of fish
The present invention relates to a composition for preventing or treating ischemic enteritis containing a DNA fragment mixture isolated from sperm or testis of fish. The composition of the present invention was verified to have excellent effects in the prevention or treatment of ischemic enteritis. In addition, the composition for preventing or treating ischemic enteritis of the present invention was verified to be safe and have few side effects even when administered for a long period of time. Therefore, a medicine for ischemic enteritis, which is safe without side effects and has an excellent treatment effect, is developed by using the composition for preventing or treating ischemic enteritis of the present invention, and thus the composition of the present invention is expected to be a great help in the treatment of ischemic enteritis. |
| US11065277B2 |
Method of ameliorating side effects of sickle cell disease treatments
A method of reducing a cerebral tissue pathology associated with a sickle cell disease therapy in a subject is provided using (i) a synthetic high-oxygen affinity hemoglobin-containing molecule or (ii) synthetically treated high-oxygen affinity blood. |
| US11065272B2 |
Oxygen reactive polymers for treatment of traumatic brain injury
Methods and compositions for treating traumatic brain injury. The methods and compositions utilize a multi-functional oxygen reactive polymer (ORP) that includes repeating units that include a reactive oxygen species (ROS) scavenging group and a polyalkylene oxide group. For theranostic applications, the oxygen reactive polymer further includes a diagnostic group. |
| US11065268B2 |
Method of preventing diarrhoea
The present invention provides a method for the prevention of the incidence of and/or a reduction in the duration of acute diarrhoea, particularly in travelers, said method comprising orally administering an oligosaccharide composition, in particular a non-digestible oligosaccharide, to a mammal. |
| US11065261B2 |
Botanical extracts and compounds from Schinus plants and methods of use
This disclosure relates to extracts from the Anacardiaceae (cashew plant family) and compositions comprising compounds contained therein. In certain embodiments, the extracts are derived from the fruit of a Schinus plant. In certain embodiments, the disclosure relates to methods of treating or preventing bacterial infections, acne, and other related uses. |
| US11065259B2 |
Methods of treating pruritus
A method of treating pruritus (itching) in a subject in need thereof is carried out by administering the subject an active agent in a treatment effective amount, wherein the active agent is a superoxide dismuate (SOD) mimetic. The SOD mimetic can be a complex of a metal (e.g., manganese) and an organic ligand, with suitable organic ligands including porphyrins, polyamines, salens, nitroxides, and fullerenes. Compositions for carrying out such methods are also described. |
| US11065257B2 |
Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors
The present invention relates to novel substituted pyrazoloazepin-4-ones with phosphodiesterase inhibitory activity, as well as to their use as therapeutic agents in the treatment of inflammatory diseases and conditions. |
| US11065255B2 |
Crystalline form of (S)-[2-chloro-4-fluoro-5-(7-morpholin-4-yl-quinazolin-4-yl)phenyl]-(6-methoxy-pyridazin-3-yl)-methanol
A crystalline form of (S)-[2-chloro-4-fluoro-5-(7-morpholin-4-yl-quinazolin-4-yl)-phenyl]-(6-methoxy-pyridazin-3-yl)-methanol can be prepared as a pharmaceutical composition. |
| US11065254B2 |
Antiviral JAK inhibitors useful in treating or preventing retroviral and other viral infections
Compounds, compositions, and methods of treatment and prevention of HIV infection are disclosed. The compounds are pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidine JAK inhibitors. Combinations of these JAK inhibitors and additional antiretroviral compounds, such as NRTI, NNRTI, integrase inhibitors, entry inhibitors, protease inhibitors, and the like, are also disclosed. In one embodiment, the combinations include a combination of adenine, cytosine, thymidine, and guanine nucleoside antiviral agents, optionally in further combination with at least one additional antiviral agent that works via a different mechanism than a nucleoside analog. This combination has the potential to eliminate the presence of HIV in an infected patient. |
| US11065251B2 |
PAK1 inhibitors and uses thereof
Methods are disclosed for treating acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) using compounds that inhibit p21 protein (Cdc42/Rac)-activated kinase (PAK1). |
| US11065250B2 |
Solid dosage forms of palbociclib
The present invention relates to solid dosage forms of palbociclib comprising a water-soluble acid. The dosage forms described herein have desirable pharmacokinetic characteristics. |
| US11065245B2 |
Priming of cancer cells with low dose naltrexone
The disclosure provides methods of treating a tumor/cancer by administering naltrexone or an analogue thereof, followed by a recovery phase, and then administering a small molecule signaling inhibitor such as PI3-kinase inhibitors, AKT inhibitors, taxanes, antimetabolites, alkylating agents and/or cell cycle inhibitors. The disclosure also provides diagnostic methods for assessing a therapeutic response to the methods of treatment. |
| US11065244B2 |
Methods of use of tetrahydroberberine (THB)
Tetrahydroberberine (THB), isolated from the Chinese herb “Corydalis ambigua”, exhibits a variety of pharmacological effects, although mechanisms of action are unclear or entirely unknown. Described herein are novel methods of using tetrahydroberberine (THB), THB analogs or derivatives, tetrahydroprotoberberines (THPB). Tetrahydroberberine (THB) and analogs such as l-stepholidine (l-SPD) potently block functional KATP channels natively expressed on midbrain dopamine neurons. Further, THB also blocks pancreatic β-cell KATP channels, and can be developed to a novel drugs for treating disease and/or conditions such as diabetes and Parkinson's disease. |
| US11065243B2 |
Inhibitors of DUX4 induction for regulation of muscle function
Disclosed are methods and compositions for the treatment of facioscapulohumeral muscular dystrophy. In some cases, the methods and compositions involve the use of kinase inhibitors include Src, Syk, Abl, Tie, Flt, ErbB, Trk, PRKDC, and Yes families to repress DUX4 expression in muscle cells. Further disclosed are methods and cell based assays for screening compounds for the treatment of facioscapulohumeral muscular dystrophy. |
| US11065238B2 |
Inhibitors of gangliosides metabolism for the treatment of motor neuron diseases
The present invention relates to inhibitors of gangliosides metabolism for treating motor neuron diseases, in particular hereditary spastic paraplegias. |
| US11065237B2 |
Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof
Provided herein are solid forms comprising {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions comprising the solid forms, methods of making the solid forms and methods of their use for the treatment of various diseases and/or disorders. |
| US11065235B2 |
Substituted methanopyrido [2, 1-a] isoindolones as mAChR modulators for treating various associated pathophysiological conditions and process for preparation thereof
The present invention relates to substituted methanopyrido [2,1-a]isoindolones of formula I, wherein, R1 is selected from phenylsulfonyl or p-toluenesulfonyl; and n=1, 2, 3; their derivatives, stereoisomers, pharmaceutically acceptable salts and pharmaceutically acceptable compositions having potential muscarinic acetylcholine receptor modulator activity. |
| US11065229B2 |
Method for reducing itching in atopic dermatitis
This invention relates to a method for treating atopic dermatitis, comprising administering an effective amount of N-acyltryptamine represented by Formula (I): wherein R represents a saturated aliphatic hydrocarbon group having 2 to 29 carbon atoms; or a pharmaceutically acceptable salt, hydrate or solvate thereof to a subject in need thereof. |
| US11065225B1 |
Ultra-low dose THC as a potential therapeutic and prophylactic agent for Alzheimer's disease
Alzheimer's disease is treated using THC (alone, or in combination with melatonin) administered in an ultra-low dose amount sufficient to (i) reduce Aß expression; (ii) reduce Aß aggregation: (iii) maintain APP expression; (iv) enhance mitochondrial functioning; (v) decrease phosphorylation of GSK3ß protein; (vi) decrease the expression of GSK3ß protein; (vii) decrease phosphorylation of Tau protein; and/or (viii) maintain Tau protein expression, in said patient without severe psychological impairments and side effects associated with higher doses of THC. |
| US11065222B2 |
Diagnostic assay and treatment for preeclampsia
The invention provides a method of diagnosis or prognosis of preeclampsia in a pregnant subject, comprising providing a sample from a pregnant subject and measuring the ratio between the amount of (a) one or both of sFlt-1 and PlGF, and (b) one or both of a breakdown product of heme and a breakdown product of arginine, in the sample. Also described are assay kits and a computer adapted for use in the method. Also described is a method of treating preeclampsia, comprising administering a pharmaceutically effective amount of L-arginine and/or citrulline and an inhibitor of arginase or pharmaceutically acceptable salts thereof. Also described is a method of treating cancer, comprising treating a subject with a therapeutically effective amount of an anti-VEGF compound, L-arginine and an arginase inhibitor. |
| US11065220B2 |
Anti-pathogenic therapeutic compositions
Therapeutic compounds useful for the treatment of pathogens including bacteria (gram positive and gram negative, mycobacteria), some fungi and viruses. The compounds described herein may include a mixture of therapeutically-effective amounts of a polar amino acid, a CI 1 fatty acid, and an anthraquinone. The invention further provides for the administration of the therapeutic compounds to a patient (e.g., a human) suffering from an infection. |
| US11065219B2 |
Treatment of nervous system disorders using combinations of RXR agonists and thyroid hormones
Disclosed herein are methods of treating disease with a combination of a RXR agonist and a thyroid hormone. |
| US11065217B2 |
Use of short chain fatty acids for the treatment and prevention of diseases and disorders
The invention relates to compositions and methods that include short chain fatty acids (SCFAs), related therapeutic compounds, and other compounds, including combinations thereof, for the treatment or prevention of diseases or disorders. |
| US11065215B2 |
Biguanide compositions and methods of treating metabolic disorders
Provided herein are methods for treating certain conditions, including diabetes, obesity, and other metabolic diseases, disorders or conditions by administrating a composition comprising a biguanide or related heterocyclic compound, e.g., metformin. Also provided herein are biguanide or related heterocyclic compound compositions, and methods for the preparation thereof for use in the methods of the present invention. Also provided herein are compositions comprising metformin and salts thereof and methods of use. |
| US11065211B2 |
Isoxylitones mediated neurogenesis
This invention provides an effective method and a composition for treating neurodegenerative diseases and conditions of the central and peripheral nervous system by stimulating neurogenesis by the use isoxylitones or an isomer, acid analog, a salt or a solvate, thereof. |
| US11065205B2 |
Immediate/delayed drug delivery
In one aspect, the present invention is concerned with a treatment where it is desired that an active agent is designed to be released immediately following administration and again at a time point some time after administration of the active agent. The present invention is particularly suited to administering an agent which may be released before sleep and whilst a subject is sleeping. As well as treating certain conditions by a particular regime, the invention also provides novel formulations for an immediate, followed by a delayed release of drug. |
| US11065202B2 |
Multi-component nanochains
A multi-component nanochain for use in diagnostic and therapeutic applications includes at least three nanoparticles linked together to form the nanochain. At least one nanoparticle of the nanochain has an asymmetric surface chemistry defined by asymmetrically disposed first linkers and second linkers. The nanoparticles are linked to form the nanochain by linking first linkers and/or second linkers disposed on separate nanoparticles. |
| US11065201B2 |
Gel formulations for local drug release
The present invention relates to a composition comprising non-water soluble carbohydrates, wherein at least 50% of the non-water soluble carbohydrates are carbohydrates selected from derivatives of lactose, maltose, trehalose, raffinose, glucosamine, galactosamine, lactosamine, or derivatives of disaccharides with at least two pyranose saccharide units, trisaccharides, tetrasaccharides, or mixtures thereof, and wherein the composition is a liquid before administration into the human or animal body and increases in viscosity by more than 1,000 centipoise (cP) after administration, for use as a medicament. |
| US11065199B2 |
Devices and methods for treating ear pain
The present invention relates generally to a methods of treating ear infections and clearing excess fluid from Eustachian tubes. |
| US11065193B2 |
Compositions and treatments for keratinous materials providing damage protection and sensorial benefits
The present invention relates to a cosmetic treatment and processes for treating keratinous materials, in particular for altering the color of hair as in hair coloration, hair color lightening or removal, and treatment of artificially colored hair, wherein the composition can include at least one antioxidant, applied separately or combined or combinable with one or more components of a color altering system in amounts sufficient to confer protection when the treatment composition is applied to keratinous material and thereby enhance and protect one or more sensorial features, and preserve the mechanical properties and native amino acid structure of the keratinous material. |
| US11065189B2 |
Liquid personal cleansing composition
The invention relates to aqueous skin cleansing compositions. Specific amounts and chain length of acyl glycinate and acyl glutamate when used in specified ratios, have been found to unexpectedly enhance lather volume and texture, as well as provide superior mildness. |
| US11065185B2 |
Hair coloring method
A hair coloring method that has a better property of keeping color quality, hardly damages hair, reduces skin damage and is free of paraphenylenediamine when performing hair dye comprises a step of applying a mixture of the following (A) and (B) in a predetermined ratio: (A) a hair coloring agent comprising at least a basic dye, an HC dye, a second amino acid, a first cationic surfactant, a thickener, an oil agent, a first pH adjuster and a wetting agent, wherein the hair coloring agent has a pH of 6.8 or more, and (B) a hair cosmetic comprising at least an alkaline agent, a first amino acid, a higher alcohol having 12 to 22 carbon atoms, a surfactant, and a thickener; a step of providing a predetermined time after applying; and a step of applying a cuticle care agent after the predetermined time. |
| US11065181B2 |
Syringe-to-syringe coupler
A syringe-to-syringe coupling for facilitating the transfer of fluids or medications from a first syringe to a second syringe. In example embodiments, the coupling includes a centrally-positioned hub extending from a first end to a second end, and a fluid delivery conduit provided within the hub and extending between the first and second ends. In example forms, each end of the hub includes a male tip. |
| US11065178B2 |
Spinal massage device
A vibrating back massager with guide slot and vibrating heads is described. The guide slot is designed to restrict lateral movement of the massage device when the guide slot is engaged with a supporting member. The supporting member may be the edge of an open door, a corner, a vertical pole, or other generally available structure. The device includes a strap handle which may be draped over the user's shoulder and used to control the vertical position of the device. The described vibrating massage device allows a single user to create and maintain a significant amount of massage pressure without fatiguing his arms or relying on a second person. In a preferred embodiment, the controls for the vibrating massage device are incorporated into the strap handle so that the speed, intensity, and/or temperature may be controlled by the user without repositioning the device. |
| US11065177B2 |
Sexual aid apparatus with safety device
A sexual aid apparatus with a safety feature includes (a) a shaft element configured to emulate a human penis and to be placed against genitals or inside a human orifice, (b) an electric vibrating motor located within the shaft element, the electric vibrating motor configured for vibrating the shaft element so as to produce sensation in a user utilizing the shaft element against genitals or inside a human orifice, (c) a flexible cord coupled to a distal end of the shaft element, the cord configured for having a tensile strength of at least 20 pounds per square inch, (d) one or more spherical elements coupled to the cord and located between ends of the cord, the spherical elements configured for insertion into a human orifice and for producing sensation in the user; and (e) one or more crystal elements coupled to the cord and located between the ends of the cord, the crystal elements configured for insertion into a human orifice and for producing sensation in the user. |
| US11065175B2 |
Leg massager
There is provided a leg massager that massages a user's leg by a position-adjustable massaging system for selectively massaging massage target areas of the leg. The leg massager includes: a lower massaging system that massages a massage target area of the user's leg L including at least user's foot F; an upper massaging system that massages an upper massage target area located above the massage target area which is massaged by the lower massaging system; a driving mechanism that drives the upper massaging system and the lower massaging system; and a rockably supporting portion that supports the upper massaging system for rocking motion about its horizontal axis. |
| US11065172B2 |
Cushioning body for a leg rest of a rollator walking aid
A cushioning body for a leg rest of a rollator walking aid is in the form of an elastic molded body and has an upper side, which, when the elastic molded body is attached to a support member of the leg rest of the walking aid and the walking aid is used by a person, faces a bent leg of the person, a lower side, and a depression disposed on the upper and/or lower side. The depression is configured as a recess or as an area in which the material of the molded body has a reduced density. In the depression, a protuberant part of the anterior surface of the knee and of the neighboring portion of the lower leg is received when a leg of a person is resting on the cushioning body, in particular when the bent leg is in contact with the upper side of the cushioning body. |
| US11065171B2 |
Assistive glove for daily activities of stroke patient
The present invention relates to an assistive glove for daily activities of stroke patient which comprises a main body, a first pulling member, a second pulling member, and plural circular strings. The main body comprises a thumb sleeve, at least one finger sleeve a palm portion connected to the thumb sleeve and the at least one finger sleeve by one side and a wrist portion connected to another side of the palm portion. The first pulling member and the second pulling member are disposed on the palm portion and having a first hook and at least one second hook corresponding to the thumb sleeve and the at least one finger sleeve. The plural circular strings are hung on the first hook and the at least one second hook and fixed to the thumb sleeve and the at least one finger sleeve respectively. |
| US11065169B2 |
Convertible examination table
There is provided herein an examination table that is capable of being converted to render either an examination configuration or a seating configuration. The table includes a planar table member having a suitable surface for the examination of a subject and is adjustable between a horizontal orientation for medical evaluation of the subject and a vertical orientation when in the table member is not in use for exams. |
| US11065168B2 |
Leg assembly for height adjustable patient support
A height adjustable patient support has a frame, a pair of motor powered leg assemblies operable to vertically raise and lower the frame between a lowermost position and an uppermost position, a guide structure for longitudinally guiding an end of at least one of the pair of leg assemblies along the frame as the at least one of the pair of leg assemblies operates to vertically raise and lower the frame, and a non-motorized structure operable to longitudinally bias the end of the at least one of the pair of leg assemblies when the frame is in the lowermost position, the non-motorized structure mounted on the patient support by a mounting structure non-rigidly secured to the patient support. The non-motorized structure may assist with raising the frame from the lowermost position until motors operating the motor powered legs are able to continue with raising the frame. |
| US11065162B2 |
Amputated leg medical wrap apparatus
An amputated leg medical wrap apparatus for securing and maintaining bandages on an amputated leg stump includes a bottom pad. A pair of straps comprises a top strap and a bottom strap each coupled to a bottom outer surface of the bottom pad. A pair of top pads comprises a right top pad and a left top pad coupled to the top strap and the bottom strap. The right top pad has a first hook-and-loop fastener coupled to a top inner surface and the left top pad has a second hook-and-loop fastener coupled to a top outer surface to secure the apparatus to a user's amputated leg stump. A belt strap is coupled to the bottom outer surface of the bottom pad and has a right belt strap extension and a left belt strap extension each having a looped top end configured to receive a waist belt. |
| US11065155B2 |
Diagnostic and surgical laser device utilizing a visible laser diode and a beam pattern generator
System and method for providing diagnostic, imaging procedures and surgical laser treatments generating patterns of laser light on target tissue of a patient. The system includes aiming and treatment light beams originating from the same visible laser emitting diode, a scanner for generating patterns of points of light of the generated light, a controller, and a user interface that allows the user to select one of several possible point of light patterns, adjusts the point of light intensity and/or duration. |
| US11065152B2 |
Systems and methods for the treatment of eye conditions
Systems, methods, and devices used to treat eyelids, meibomian glands, ducts, and surrounding tissue are described herein. In some embodiments, an eye treatment device is disclosed, which includes a scleral shield positionable proximate an inner surface of an eyelid, the scleral shield being made of, or coated with, an energy-absorbing material activated by a light energy, and an energy transducer positionable outside of the eyelid, the energy transducer configured to provide light energy at one or more wavelengths, including a first wavelength selected to heat the energy-absorbing material. |
| US11065151B2 |
Therapeutic agent formulations for implanted devices
An injectable formulation of therapeutic agent may comprise the therapeutic agent and a stabilizer such that a substantial portion of the stabilizer remains in the therapeutic device to stabilize the therapeutic agent when the therapeutic agent is released from the therapeutic device. The injectable formulation may comprise one or more of binding agent particles or erodible material particles, such that the formulation can be injected into the therapeutic device. The binding agent particles can bind reversibly to the therapeutic agent so as to modulate release of the therapeutic agent, and the erodible material particles can generate protons of an acid so as to increase stability of the therapeutic agent and may modulate release of the therapeutic agent. The therapeutic agent can be combined with one or more of the stabilizer, the binding agent particles or the erodible particles to increase stability of the therapeutic agent and may modulate release. |
| US11065150B2 |
Dual balloon fluid endometrial treatment of uterine tissue
A medical device includes: a shaft having a distal end and an associated exhaust channel; a first balloon configured to be attached to the distal end of the shaft, the first balloon having an outer surface that is substantially conformal to an inner surface of a uterine cavity; and a second balloon configured to be received within the first balloon and forming an intermediary space between the first balloon and an outer surface of the second balloon. The second balloon includes at least one rupture valve configured to rupture at a predefined pressure in the intermediary space. |
| US11065149B2 |
Portable therapeutic system using hot or cold temperature
Disclosed is a system which employs a cooling or heating pad which is preferably rechargeable with hot or cold temperatures at an intended area of the body. The pad includes a highly temperature-conductive or temperature-retentive material which can be cooled or heated using a portable source of heat or cold material delivered to the pad by a removable delivery conduit. Valves can be included to regulate flow of the cooling or heating material from the source to the pad. The system can also include a dual-chambered canister for containing two different media for heating, cooling or for alternating heating and cooling the pad. |
| US11065147B2 |
Devices, systems, and methods for pre-heating fluid to be introduced into a patient during a surgical procedure
A surgical system includes a fluid source including a fluid inflow tube, a fluid delivery device coupled to the fluid inflow tube and configured to deliver fluid from the fluid source into a patient, a surgical instrument, and a control box coupled to the surgical instrument. The control box includes one or more waste heat-generating electronic components and a heat pipe assembly disposed in thermal communication with the one or more waste heat-generating electronic components. The fluid inflow tube is disposed in thermal communication with the heat pipe assembly of the control box such that the heat pipe assembly conducts heat away from the one or more waste heat-generating electronic components and heats fluid flowing through the fluid inflow tube. |
| US11065145B2 |
Sphincter-type intestinal valve
The present invention relates to a biocompatible device that integrates electromagnetic and mechanical elements and allows the combination of different mechanisms for voluntary closing of the intestinal lumen. The device can be used either with a stoma to control intestinal transit to the outside and avoid the use of collection pouches, or without a stoma to regulate intestinal transit for another medically necessary reason. |
| US11065143B2 |
Wheelchair body harness
A wheelchair body harness system and method for manufacturing such system comprising a vest portion and seat area created by a strap secured between a patient's legs. The wheelchair body harness may contain a zipper along the center of the patient's chest and abdomen area of the vest portion. Adjustable side and shoulder panels may also be included to accommodate patients of different sizes. The wheelchair body harness may contain straps and buckle members across the patient's sides and shoulders that correspond to straps and buckle members located on a wheelchair or wheelchair insert. The vest portion may contain a Velcro section on the posterior side to adhere to a Velcro back of a wheelchair or wheelchair insert. The vest portion may also contain snap parts interspersed throughout the Velcro section to snap onto mating snap parts on the Velcro back of the wheelchair or wheelchair insert. |
| US11065140B2 |
Rotatable stent delivery apparatus to cover access site
Methods, apparatuses and systems are described for expandable stent delivery apparatus to cover an access site. The method may include delivering a stent delivery system through an access site, where the stent delivery system comprises a positioning member with a first portion that is rotatable with respect to a second portion, and where the stent is releasably coupled with the first portion of the positioning member. In some cases, the method may further include withdrawing an outer constrainment member from the stent to deploy a proximal portion of the stent within the body lumen and rotating the proximal portion of the stent away from the access site by withdrawing the positioning member proximally and back through the access site. The method may further include covering the access site with the proximal portion of the stent upon fully deploying the proximal portion from the outer constrainment member. |
| US11065139B2 |
Apparatuses for stent delivery and positioning to cover an access site
Methods, apparatuses and systems are described for stent delivery and positioning to cover an access site. A stent delivery system may include a tubular member configured to advance through an access site and a primary constrainment member configured to releasably couple the stent to the tubular member. The stent delivery system may further include a secondary constrainment member at least partially disposed around the primary constrainment member, the stent, and the tubular member. In some cases, the tubular member and the primary constrainment member may be configured to reposition the stent within the body lumen after removal of the secondary constrainment member such that at least a portion of the stent covers the access site after withdrawal of the tubular member, the primary constrainment member, and the secondary constrainment member from the body lumen through the access site. |
| US11065138B2 |
Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system
The present disclosure relates to a delivery catheter and the stepwise release of a stent from the catheter into the vasculature of a patient, as well as a loading device for a transcatheter heart valve (THV) prosthesis. |
| US11065136B2 |
Vascular expandable devices
Vascular expandable devices and associated methods are disclosed herein. An expandable vascular device can be implantable across an aneurysm in a blood vessel of a patient. The device can include a generally tubular structure formed of a plurality of braided metallic elements. The device can have a compressed state with a compressed state diameter of 0.027 inches or less and an expanded state with an expanded state diameter of 1.75 mm or more. Each of the plurality of metallic strands can have an oxide layer having a thickness of about 400 angstroms or less. The tubular structure can be configured to self-expand from the compressed state to the expanded state. |
| US11065132B2 |
Method of expanding a space between opposing tissue surfaces
An expandable device for expanding and supporting body tissue comprises an inferior endplate having an outer surface configured to contact one body tissue surface and a superior endplate having an outer surface configured to contact an opposing body tissue surface. The inferior endplate and the superior endplate are movable relative to each other in a direction of expansion. The device includes an elevator captively supported between the inferior endplate and the superior endplate for independent movement along the direction of expansion. In the first direction the elevator is moved toward said superior endplate to lift the superior endplate and expand the device. In the second direction the elevator moves away from said superior endplate toward said inferior endplate to create a space for insertion of an insert into the expanded device. |
| US11065131B2 |
Interbody fusion system and methods
A portal system for intervertebral surgical fusion procedures includes a longitudinally elongated hollow tubular body comprising a first wall, a second wall opposing the first and a third wall spanning from a first edge of the first wall to a first edge of the second wall. A channel is defined longitudinally through at least one of the first, second and third end walls. The fourth wall of the body is at least partially open or can be completely enclosed. |
| US11065130B2 |
Expandable spinal implant system and method of using same
An expandable spinal implant includes a distal projection extending from only one side of the implant, ending in an anterior tip, the anterior portion and anterior tip defining an elongated distal end hook, which is wider than the proximal end. The distal end hook rotates around the spinal cord, aligning the implant with a desired pathway, then inserts into place in the disc space between the vertebrae. The elongated widened distal end hook provides a TLIF approach, distributes loads, provides anterior rim engagement, and creates lordosis. |
| US11065129B2 |
Expandable intervertebral fusion device
An expandable intervertebral fusion device is provided including a core, an upper endplate for contacting a first vertebral body and a lower endplate for contacting a second vertebral body. The expandable intervertebral fusion device is configurable in a first state, a second state and a third state. In the first state, the upper and lower endplates are generally planar to one another and define a first height. In the second state, the upper and lower endplates remain generally planar to one another and define a second height greater than the first height. In the third state, a lordotic angle is defined between the upper and lower end plates. |
| US11065128B2 |
Intervertebral implants and related methods of use
A method of implanting an intervertebral spacer may include positioning the intervertebral spacer within an intervertebral space defined by adjacent vertebral bodies. The intervertebral spacer may include a plurality of bores, and each of the plurality of bores may be configured to receive either a linear fastening element or a curvilinear fastening element. The method also may include selecting a first fastening element from a group including linear fastening elements and curvilinear fastening elements, and inserting the first fastening element into a first bore of the plurality of bores such that the first fastening element is inserted into one of the adjacent vertebral bodies to secure the intervertebral spacer within the intervertebral space. |
| US11065124B2 |
Variable thickness femoral augments
A femoral assembly includes a femoral component that includes condylar portions and an anterior flange portion. The condylar portions and anterior flange portion together define an outer side of the femoral component for articulating with a tibial prosthesis and an inner bone facing side opposite the outer side. The inner bone facing side defines five intersecting component inner surfaces that each extend from a lateral side of the femoral component to a medial side thereof. A femoral augment includes condylar portions and an anterior flange portion. The condylar portions and anterior flange portion together define an outer side of the femoral augment comprised of five intersecting augment outer surfaces and an inner side comprising no more than three intersecting augment inner surfaces. The augment outer surfaces correspond to the component inner surfaces of the femoral component. The augment inner surfaces correspond to resected surfaces of a distal femur. |
| US11065123B2 |
Compression resistant implants including an oxysterol and methods of use
Provided is a compression resistant implant configured to fit at or near a bone defect to promote bone growth, the compression resistant implant comprising porous ceramic particles in a biodegradable polymer, and an oxysterol disposed in or on the compression resistant implant. Methods of making and use are further provided. |
| US11065119B2 |
Long arm valve repair clip
Fixation device for engaging tissue including a pair of fixation elements, each fixation element has a first end and a second end opposite the first end, the first ends are moveable between a closed position and an open position. The fixation device further includes a pair of gripping elements. Each gripping element is moveable with a respective fixation element and disposed in opposition to at least a portion of the respective fixation element to capture tissue therebetween. The fixation device further includes a central portion operatively connected to each gripping element at a respective central portion-gripping element interface. The central portion has at least one distal end and a width “W1” proximate the distal end. Each of the gripping elements has a free end opposite its respective central portion-gripping element interface and a length “L1” defined between the respective central portion-gripping element interface and the free end. The length L1 fixation elements is at least about three times the width W1. |
| US11065116B2 |
Apparatus and methods for trans-septal retrieval of prosthetic heart valves
In some embodiments, a method for transfemoral retrieval and/or repositioning of a prosthetic valve (400) implanted within a heart includes inserting a retrieval assembly through a femoral vein and into a heart until a distal end portion of the retrieval assembly is disposed in an atrium of the heart. The prosthetic valve is formed with a shape-memory material. The retrieval assembly (402) includes an outer catheter (403), a middle catheter (404), a snare catheter (406), and a snare member (415). The snare member is moved distally out of a lumen of the snare catheter and into engagement with an inner frame (440) of the prosthetic valve. The retrieval assembly can invert an outer frame (410) of the prosthetic valve to collapse and retract the valve into a lumen of the retrieval assembly. In some embodiments, a positioning catheter (419) can be inserted through the apex of the heart to assist in positioning and inverting the prosthetic valve. |
| US11065115B2 |
Prosthetic heart valve having an inner frame and an outer frame
Prosthetic heart valves are described. Prosthetic heart valves can include radially expandable and compressible inner and outer metal frames. The inner frame can be disposed within a lumen of the outer frame and can be coupled to the outer frame. An outflow end of the inner frame can be coupled to and/or located at an outflow end of the outer frame. An end portion of the inner frame can be spaced radially inwardly from an inner surface of the outer frame, such that a radial gap exists between the inner surface of the outer frame and an outer surface of the inner frame. Prosthetic heart valves can further include a plurality of leaflets disposed within and supported by the inner frame, such as by commissure posts of the inner frame. |
| US11065112B2 |
Frame with integral sewing cuff for prosthetic valves
Described embodiments are related to a prosthetic valve for surgical placement with a sewing cuff durably attached to a frame. The durability of the attachment is accomplished by sandwiching a fabric between the frame and a composite material. The fabric extends beyond the frame base to form a sewing cuff that is integral to a frame assembly. The sewing cuff facilitates tissue ingrowth while tissue ingrowth is discouraged elsewhere around the frame. |