Document Document Title
US10900160B2 Laundry treatment apparatus
A laundry treatment apparatus generates water stream during pre-washing so that pre-washing and soaking of laundry is performed automatically by the water stream; and upon completing of pre-washing, main washing is performed using a washing machine. The laundry treatment apparatus includes: a cabinet; a sink bowl provided at a top of the cabinet, and having an accommodation space which accommodates laundry and wash water and has an open top; a faucet which is provided at the sink bowl and supplies the wash water to the accommodation space; a water stream generator which is provided on at least one side of the accommodation space in the sink bowl and generates water stream to the wash water accommodated in the accommodation space; and a drawer type washer which is provided below the sink bowl to move forward and rearward in the cabinet, and performs washing, rinsing, and spin-drying of the laundry.
US10900159B2 Batting bin
A long arm quilting machine with a batting bin has been developed. The batting bin includes an elongated partially enclosed trough that attaches to the quilting machine and extends, in length, more than 50% of a longest dimension of the quilting machine. The batting bin includes one or more support members to support a position of the trough in relation to the quilting machine. The trough has an open upper portion which allows batting material to be dispensed upward into the quilting machine. The trough has an enclosed lower portion such that batting material within the trough is kept from touching a floor the quilting machine is positioned over.
US10900155B2 Instrument for making ribbon embellishment
An instrument for making a ribbon embellishment is provided. The instrument is made up of a ring-shaped plate, and a plurality of extensions each extending from the ring-shaped plate toward the center of the circular plate. The plurality of extensions include a first extension, a second extension and a third extension, and the first extension has a first surface and a second surface opposite to the first surface. In plan view, the second extension faces the first surface of the first extension, and the third extension faces the second surface of the first extension.
US10900154B2 Knit fabric with electrical components
Conductive yarns in a knitted fabric may include insulating cores covered with metal layers that form signal paths. Open circuits may be formed in the yarns by removing metal from the insulating cores at selected locations within the yarns. The fabric may be formed from rows of interlocked loops of the yarn. The open circuits may be located on the loops so that each loop with an open circuit has a first segment of the metal layer that is separated from a second segment of the layer by a portion of the loop from which the metal layer has been removed. Each electrical component may have terminals that span a respective one of the open circuits and that are shorted respectively to the metal of the first and second segments.
US10900144B2 Roving-forming element for a roving machine as well as a roving machine equipped therewith
A yarn-forming element is provided for a roving machine that produces a roving from a fiber structure using compressed air. The yarn-forming element includes an intake opening for fibers of the fiber structure, an outlet for emergence of the roving produced from the fiber structure, and a draw-off channel that connects the intake opening and the outlet. A front end surrounding the intake opening is formed as a first truncated cone in at least some sections thereof. The first truncated cone includes a larger base surface and a smaller opposite cover surface that is adjacent the draw-off channel. An angle (α) between a lateral line of the first truncated cone and an axis of the first truncated cone is less than 90° and greater than 70°.
US10900142B2 Apparatus for manufacturing a second substrate on a first substrate including removal of the first substrate
An apparatus includes a deposition chamber housing that accommodates a growth substrate, a supply nozzle to supply a deposition gas for forming a target large-size substrate on the growth substrate into the deposition chamber housing, a susceptor to support the growth substrate and expose a rear surface of the growth substrate to an etch gas, and an inner liner connected to the susceptor. The inner liner is to isolate the etch gas from the deposition gas and guide the etch gas toward the rear surface of the growth substrate. The susceptor includes a center hole that exposes the rear surface of the growth substrate and a support protrusion supporting the growth substrate, the support protrusion protruding toward the center of the center hole from an inner sidewall of the susceptor defining the center hole.
US10900139B2 Bicycle gear and method for manufacturing such a gear
A bicycle gear having a first coating layer obtained by a plasma electrolytic oxidation treatment and a second coating layer, overlapped on the first coating layer, that is a lubricating substance, preferably a fluoropolymer.
US10900134B2 Electrolytic generation and purification of carbon
The embodiments herein relate to methods, apparatus, and systems for forming and purifying solid carbon material from a molten carbonate salt electrolyte. Various embodiments also provide methods, apparatus, and systems for recycling certain materials including the carbonate salt electrolyte, carbon dioxide, water, etc. Advantageously, the system utilizes carbon dioxide in one or more processes, for example to purify the solid carbon and regenerate the carbonate salt electrolyte. These methods, apparatus, and systems provide an efficient technique to consume carbon dioxide in the production of solid carbon, with substantial advantages over systems that attempt to form solid carbon from a stream of carbon dioxide provided directly to an electrolysis reactor.
US10900133B2 Nitride catalyst and method for manufacturing the same
A method for manufacturing nitride catalyst is provided, which includes putting a Ru target and an M target into a nitrogen-containing atmosphere, in which M is Ni, Co, Fe, Mn, Cr, V, Ti, Cu, or Zn. The method also includes providing powers to the Ru target and the M target, respectively. The method also includes providing ions to bombard the Ru target and the M target for depositing MxRuyN2 on a substrate by sputtering, wherein 0
US10900125B2 Apparatus for susceptor temperature verification and methods of use
Apparatus and methods for processing a semiconductor wafer in which a sensor (e.g., a contact thermocouple) is positioned in the gas distribution assembly measures temperature and/or a film parameter before, during and/or after deposition are described.
US10900124B2 Substrate processing chamber with showerhead having cooled faceplate
A showerhead for a substrate processing chamber includes: inner walls; an inner plenum between the inner walls; and a faceplate having a first surface and a second surface that is opposite the first surface. Holes through the faceplate extend from the first surface to the second surface. A first inlet is fluidly connected to the inner plenum. A first outer plenum is between the inner walls and outer walls. A second outer plenum is between the inner walls and the outer walls. Coolant: fluidly connect the first outer plenum with the second outer plenum; are located within the faceplate between the first and second surfaces; and are fluidly isolated from the holes. The showerhead also includes a second inlet that is fluidly connected to the first outer plenum.
US10900122B2 Apparatus for semiconductor wafer processing
A spatial atomic layer deposition apparatus (10), including a showerhead (16) with a showerhead side (18) having a center, a central area and a circumferential area. The apparatus also includes a susceptor (12) having a substrate support side that extends parallel to and of opposite the showerhead side forming a gap. The susceptor and the showerhead are rotatable relative to each other around an axis of rotation. The apparatus has a plurality of switchable showerhead sections. The apparatus also includes a plurality of multi-way valve assemblies. Each switchable showerhead section is fluidly connected with one of the plurality of multi-way valve assemblies, so as to fluidly connect a selected one of a plurality of different gas sources with that switchable showerhead section.
US10900120B2 Passivation against vapor deposition
Passivation layers to inhibit vapor deposition can be used on reactor surfaces to minimize deposits while depositing on a substrate housed therein, or on particular substrate surfaces, such as metallic surfaces on semiconductor substrates to facilitate selective deposition on adjacent dielectric surfaces. Passivation agents that are smaller than typical self-assembled monolayer precursors can have hydrophobic or non-reactive ends and facilitate more dense passivation layers more quickly than self-assembled monolayers, particularly over complex three-dimensional structures.
US10900118B2 Magnetically enhanced low temperature-high density plasma-chemical vapor deposition plasma source for depositing diamond and diamond like films
A magnetically enhanced low temperature high density plasma chemical vapor deposition (LT-HDP-CVD) source has a hollow cathode target and an anode, which form a gap. A cathode target magnet assembly forms magnetic field lines substantially perpendicular to the cathode surface. A gap magnet assembly forms a magnetic field in the gap that is coupled with the cathode target magnetic field. The magnetic field lines cross the pole piece electrode positioned in the gap. The pole piece is isolated from ground and can be connected to a voltage power supply. The pole piece can have negative, positive, floating, or RF electrical potentials. By controlling the duration, value, and sign of the electric potential on the pole piece, plasma ionization can be controlled. Feed gas flows through the gap between the hollow cathode and anode. The cathode can be connected to a pulse power or RF power supply, or cathode can be connected to both power supplies. The cathode target and substrate can be inductively grounded.
US10900117B2 Plasma corridor for high volume PE-CVD processing
A coating system includes a coating chamber having a peripheral chamber wall, a top wall, and a bottom wall. The peripheral chamber wall defines a chamber center. A plasma source is positioned at the chamber center. The coating system also includes a sample holder that holds a plurality of substrates to be coated which is rotatable about the chamber center at a first distance from the chamber center. A first isolation shield is positioned about the chamber center at a second distance from the chamber center, the first isolation shield being negatively charged.
US10900111B2 Method for producing surface-modified component
A method for producing a surface-modified component includes: a process of forming a thermal sprayed coating on a substrate; a process of irradiating a surface of the thermal sprayed coating with a high energy beam so as to cause an entirety of the thermal sprayed coating and a part of the substrate in a thickness direction to melt and then solidify, and thereby forming a densified modified layer; a process of forming a thermal sprayed coating on the modified layer which has been formed in the latest; and a process of irradiating a surface of the thermal sprayed coating with a high energy beam so as to cause an entirety of the thermal sprayed coating and a part of the modified layer which has been formed in the latest in the thickness direction to melt and then solidify, and thereby forming a densified modified layer.
US10900110B2 Method for the hot forming of a steel component
A method for hot forming a steel component is provided. The steel component is heated into a range of complete or partial austenitization in a heat treatment step. The heated steel component is both hot-formed and quench-hardened in a forming step. A first pretreatment step precedes the heat treatment step in terms of process, in which first pretreatment step the steel component is provided with a corrosion-resistant protective layer in order to protect against scaling in the heat treatment step. Before the heat treatment step is performed, a surface oxidation process occurs in a second pre-treatment step, in which a weakly reactive, corrosion-resistant oxidation layer is formed on the scale protection layer by means of which oxidation layer abrasive tool wear is reduced in the forming step.
US10900105B2 Low-density hot-or cold-rolled steel, method for implementing same and use thereof
A rolled steel sheet is provided. The rolled steel sheet has a mechanical strength greater than or equal to 600 MPa and an elongation at fracture that is greater than or equal to 20%. A a method for its fabrication is also provided. The chemical composition of the steel sheet includes 0.10≤C≤0.30%, 6.0≤Mn≤15.0%, 6.0≤Al≤15.0%, and optionally one or more elements selected from among: Si≤2.0%, Ti≤0.2%, V≤0.6% and Nb≤0.3%. The remainder of the composition includes iron and the unavoidable impurities resulting from processing. The ratio of the weight of manganese to the weight of aluminum is such that Mn Al > 1.0 . The microstructure of the sheet includes ferrite, austenite and up to 5% Kappa precipitates in area fraction.
US10900104B2 Hot rolled steel sheet and method for manufacturing the same
A method for manufacturing a hot rolled steel sheet having a low yield ratio and that is excellent in low-temperature toughness, the steel sheet having a specified chemical composition. The method comprises hot rolling a steel material into a steel sheet, cooling the steel material using a cooling process comprising a first cooling and a second cooling, and performing a coiling process on the steel sheet in such a manner that the coiling temperature is 450° C. or more in terms of surface temperature of the steel sheet.
US10900101B2 Copper alloy for dental prosthesis
The present invention relates to a copper alloy for dental prosthesis and specifically, to a copper alloy for dental prosthesis having such color and luster that the copper alloy can be used as a substitute for a gold alloy and having excellent resistance to corrosion, wherein the copper alloy comprises, in wt %, 7-10% of Al, 1-2.5% of In, 1-2.5% of Sn, 2-4% of Fe, 2-3.5% of Ni, 2.5-4% of Mn, 2-5% of Zn, and the balance Cu.
US10900100B2 Hot rolled steel sheet
A hot rolled steel sheet having a chemical composition consisting of, in mass %, C: 0.020-0.180%, Si: 0.05-1.70%, Mn: 0.50-2.50%, Al: 0.010-1.000%, N: 0.0060%, P≤0.050%, S≤0.005%, Ti: 0-0.150%, Nb: 0-0.100%, V: 0-0.300%, Cu: 0-2.00%, Ni: 0-2.00%, Cr: 0-2.00%, Mo: 0-1.00%, B: 0-0.0100%, Mg: 0-0.0100%, Ca: 0-0.0100%, REM: 0-0.1000%, Zr: 0-1.000%, Co: 0-1.000%, Zn: 0-1.000%, W: 0-1.000%, the balance: Fe and impurities, wherein a metal microstructure includes, in area %, at a position ¼ W or ¾ W from an end face of the steel sheet and ¼ t or ¾ t from a surface, martensite: more than 2%-10%, retained austenite <2%, bainite 40%, pearlite 2%, the balance: ferrite, an average circle-equivalent diameter of a metallic phase constituted of martensite/retained austenite is 1.0-5.0 μm, an average of minimum distances between adjacent metallic phases is 3 μm or more, and a standard deviation of nano hardness is 2.0 GPa or less.
US10900099B2 Steel H-shape for low temperature service and manufacturing method therefor
Provided is a steel H-shape for low temperature service including a predetermined chemical composition. A CEV obtained by CEV=C+Mn/6+(Cr+Mo+V)/5+(Ni+Cu)/15 is 0.40 or less. A sum of an area ratio of one or both of ferrite and bainite at a 1/4 position from an outer side across a thickness of a flange and a 1/6 position from an outer side across a flange width is 90% or more, and an area ratio of a hard phase is 10% or less. An effective grain size is 20.0 μm or less, and a grain size of the hard phase is 10.0 μm or less. 30 pieces/mm2 or more Ti oxides having an equivalent circle diameter ranging from 0.01 to 3.0 μm are included. The thickness of the flange ranges from 12 to 50 mm.
US10900091B2 miR-133a as a marker for colorectal cancer
The present invention provides methods for assessing the likelihood of effectiveness of chemotherapy such as oxaliplatin treatment in colorectal cancer patients as well as their survival prospect by determining the level of miR-133a in the cancer tissue. A kit useful for such methods are also provided.
US10900088B2 Personalized tumor biomarkers
Clinical management of human cancer is dependent on the accurate monitoring of residual and recurrent tumors. We have developed a method, called personalized analysis of rearranged ends (PARE), which can identify translocations in solid tumors. Analysis of four colorectal and two breast cancers revealed an average of nine rearranged sequences (range 4 to 15) per tumor. Polymerase chain reaction with primers spanning the breakpoints were able to detect mutant DNA molecules present at levels lower than 0.001% and readily identified mutated circulating DNA in patient plasma samples. This approach provides an exquisitely sensitive and broadly applicable approach for the development of personalized biomarkers to enhance the clinical management of cancer patients.
US10900078B2 Methods, devices, and systems for analyte detection and analysis
Provided are systems and methods for analyte detection and analysis. A system can comprise an open substrate. The open substrate may be configured to rotate or otherwise move. The open substrate can comprise an array of individually addressable locations, with analytes immobilized thereto. The substrate may be spatially indexed to identify nucleic acid molecules from one or more sources, and/or sequences thereof, with the respective one or more sources. A solution comprising a plurality of probes may be directed across the array to couple at least one of the plurality of probes with at least one of the analytes to form a bound probe. A detector can be configured to detect a signal from the bound probe via scanning of the substrate while minimizing temperature fluctuations of the substrate or optical aberrations caused by bubbles.
US10900076B2 Self assembled patterning using patterned hydrophobic surfaces
Embodiments provided herewith are directed to self-assembled methods of preparing a patterned surface for sequencing applications including, for example, a patterned flow cell or a patterned surface for digital fluidic devices. The methods utilize photolithography to create a patterned surface with a plurality of microscale or nanoscale contours, separated by hydrophobic interstitial regions, without the need of oxygen plasma treatment during the photolithography process. In addition, the methods avoid the use of any chemical or mechanical polishing steps after the deposition of a gel material to the contours.
US10900070B2 Multiplex analysis of gene expression in individual living cells
The technology as disclosed herein relates to methods, compositions and kits for multiplex measuring levels of expression of target RNA species (e.g., mRNA and non-coding RNAs) in single, living cells. Aspects of the invention relate to, in part, a duplex-binding protein which is labeled with a FRET dye, and a RNA-binding probe, which comprises a spectrally paired FRET dye and specifically hybridizes to a target RNA. When the RNA-binding probe binds to a target RNA, a duplex is formed, which is allows binding of the duplex-binding protein bringing the two FRET dyes into close proximity and allowing fluorescence resonance energy transfer (FRET) reaction and a detectable change in fluorescence, which determines the amount of target RNA species in the living cell. Aspects of the invention also include, kits, vectors and polynucleic acid sequences of the duplex-binding protein and RNA-binding probes disclosed herein, and cell and cell lines comprising the same.
US10900067B2 Nucleic acid nanoparticles for analyte detection
Provided is a highly multiplex approach to disease condition diagnostics that combines nanopore sensing and nucleic acid nanoparticle (NANP) design and synthesis to detect multiple biomarkers to diagnose diseases. The system works by taking a sample containing biomarkers that is mixed with a plurality of nucleic acid nanoparticle (NANP) populations, with each population designed and synthesized to be able to detect a particular biomarker. Upon incubation, the mixture is used with nanopore measurements, with recordings of the ionic current through the nanopore. The ionic current recordings are analyzed, which determines the presence and/or concentration of biomarkers in the sample.
US10900063B2 Measurement of Lp-PLA2 activity
An object of the present invention is to provide a highly versatile, simple and safe method for measuring Lp-PLA2 activity. Another object of the present invention is to provide an accurate and highly sensitive method for measuring Lp-PLA2 activity. Provided is a method for measuring lipoprotein-associated phospholipase A2 (Lp-PLA2) activity in a sample containing Lp-PLA2, the method comprising the following steps (A) to (C): (A) converting PAFs into lyso-PAFs by reacting the PAFs with the Lp-PLA2 in the sample; (B) hydrolyzing the lyso-PAFs produced in the step (A) with an enzyme (lyso-PAF-PLD) to obtain hydrolysate; and (C) measuring Lp-PLA2 activity in the sample by utilizing a quantitative change attributable to the hydrolysate obtained in step (B) as an indicator.
US10900062B2 Process for determining viability of test microorganisms of biological indicator and sterilization detection device for determining same
A process for determining the viability of a biological indicator includes exposing the biological indicator to a viability detection medium, the biological indicator including test microorganisms, the exposing the biological indicator to the viability detection medium producing a gaseous reaction product when one or more of the test microorganisms are viable. The presence or absence of the gaseous reaction product produced by the biological indicator combined with the viability detection medium is detected with a sensing device, the sensing device comprising a resistive sensor, wherein the presence of the gaseous reaction product indicates the presence of viable test microorganisms and the absence of the gaseous reaction product indicates the absence of viable test microorganisms. A sterilization detection device includes a container configured to contain the biological indicator, a viability detection medium, and the sensing device.
US10900061B2 Method for detecting a substance in a sample using modified bacteriophages
The present invention provides a binding assay that employs an activatable dormant bacteriophage carrying a reporter gene to qualitatively or quantitatively detect the presence of a substance of interest in a sample. Also provided is a simple culture device that is designed for manufacture and use in areas of limited resources. The device is useful for cell culture in such environments with limited resources because cells grow in paper just as they do in a culture dish.
US10900055B2 Engineered tyrosine ammonia lyase
The present invention provides engineered tyrosine ammonia-lyase (TAL) polypeptides and compositions thereof. In some embodiments, the engineered TAL polypeptides have been optimized to provide enhanced catalytic activity and enhanced acid stability, while reducing sensitivity to proteolysis and increasing tolerance to acidic pH levels. The invention also provides methods for utilization of the compositions comprising the engineered TAL polypeptides for therapeutic and industrial purposes.
US10900053B2 Genome-modified recombinant adeno-associated virus vectors
Provided herein are recombinant adeno-associated virus (rAAV) nucleic acid vectors that comprise one or more modifications within at least one inverted terminal repeat (ITR) region. Exemplary modifications include ITR sequences comprising a glucocorticoid responsive element and/or a transcription factor binding site. Also provided are plasmids, libraries, rAAV particles, compositions, kits, and methods related to such vectors.
US10900051B2 Gene for improving plant disease resistance and use thereof
The ReXEG1 gene for improving plant disease resistance has a nucleotide sequence as shown in SEQ ID NO. 1, and encodes a product having an amino acid sequence as shown in SEQ ID NO. 3. It has a key role in resistance of tobacco to Phytophthora pathogens. Overexpression of this gene significantly promotes the resistance of tobacco to various Phytophthora species, and is a desirable gene for enhancing the plant disease resistance. The gene is allowed to express in tobacco by genetic transformation to improve resistance to various pathogens to tobacco, thereby improving the disease resistance of crops in field.
US10900049B2 Tissue specific reduction of lignin
The present invention provides an expression cassette comprising a polynucleotide that encodes a protein that diverts a monolignol precursor from a lignin biosynthesis pathway in the plant, which is operably linked to a heterologous promoter. Also provided are methods of engineering a plant having reduced lignin content, as well as plant cells, plant parts, and plant tissues from such engineered plants.
US10900047B2 Polypeptides having beta-xylosidase activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having beta-xylosidase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
US10900046B2 Seed- and funiculus-preferential promoters and uses thereof
The present invention relates to Brassica sequences comprising seed- and funiculus-preferential promoter activity. Provided are recombinant genes comprising the seed- and funiculus-preferential promoter operably linked to a heterologous nucleic acid sequence, and cells, plants and seeds comprising the recombinant gene. The promoters can be used to alter gene expression preferentially in the seeds and in the funiculus and to alter biotic or abiotic stress tolerance, yield, seed quality or seed properties.
US10900044B2 Listeria-based compositions comprising a peptide minigene expression system and methods of use thereof
This disclosure provides compositions, including Listeria delivery vectors comprising minigene expression constructs, and methods of using the same for inducing an immune response against an antigen-expressing tumor and for treating the same, and vaccinating against the same in subjects bearing the tumors.
US10900041B2 Antisense oligonucleotides for use in treating Alzheimer's disease
The invention relates to oligonucleotides suitable for use in treating human disease. More in particular the invention—relates to antisense oligonucleotides suitable for the treatment of Alzheimer's disease.
US10900039B2 Methods for treating aging and skin disorders using nucleic acids targeting Tyr or MMP1
The present invention relates to RNAi constructs with improved tissue and cellular uptake characteristics and methods of use of these compounds in dermal applications.
US10900037B2 Targeted self-assembly of functionalized carbon nanotubes on tumors
Provided herein is the two component self-assembly single wall nanotube system and the single wall nanotube construct that is the second component. The two component self-assembly single wall nanotube system has a morpholino oligonucleotide with a targeting moiety followed by a single wall nanotube construct with second morpholino oligonucleotides complementary to the first morpholino oligonucleotides and one or both of a therapeutic or diagnostic payload molecule linked to the single wall nanotube construct.
US10900030B2 Structured substrates for improving detection of light emissions and methods relating to the same
A structured substrate (100) including a substrate body (102) having an active side (104). The substrate body (102) includes reaction cavities or sites (106) that open along the active side (104) and interstitial regions (118) that separate the reaction cavities (106). The structured substrate (100) includes an ensemble amplifier (120) positioned within each of the reaction cavities (106). The ensemble amplifier (120) includes a plurality of nanostructures (116), such as dimers, trimers, bowtie nanoantenna, nanorods, nanorings, nanoplugs, configured to at least one of amplify electromagnetic energy (108) that propagates into the corresponding reaction cavity (106) or amplify electromagnetic energy (110), such as emitted fluorescence, that is generated within the corresponding reaction cavity (106). Preferably the nanostructures (116) within the cavities (106) are covered with a organic material such as a gel (122). Preferably nanoimprint lithography (NIL) is used for manufacturing the structured substrate (100).
US10900026B2 Sortase
Reported herein is a sortase comprising an amino acid sequence that is at least 90% identical to the amino acid sequence of SEQ ID NO: 11 and that comprises the mutations D101S and K137S.
US10900025B2 Recombinant B11 bacteriophages and uses thereof
The present disclosure provides compositions including recombinant B11 bacteriophages, methods for making the same, and uses thereof. The recombinant B11 bacteriophages disclosed herein are useful for the identification and/or antibiotic susceptibility profiling of specific bacterial strains/species present in a sample.
US10900024B2 Method for purifying viruses or virus-like particles using a crosslinked cellulose hydrate membrane
The present invention relates to a method for purifying viruses or virus-like particles using a crosslinked cellulose hydrate membrane and to a kit for purifying viruses or virus-like particles and the use thereof.
US10900021B2 Drying formulation for hydrogel microcarriers
A method of making a cell culture article is provided. The method includes forming a microcarrier from a microcarrier composition comprising a polygalacturonic acid compound or an alginic acid compound, infiltrating the microcarrier with a drying formulation to form an infiltrated microcarrier, and drying the infiltrated microcarrier to form a dried microcarrier, wherein the drying formulation comprises at least one of a saccharide and a monovalent cation.
US10900020B2 Methods for culturing minimally-passaged fibroblasts and uses thereof
The present invention relates to novel methods of growing at least 100 million minimally-passaged fibroblasts from a small biopsy specimen. The invention includes methods wherein a small biopsy specimen is seeded directly into a large tissue culture flask, and passaged no more than three times.
US10900011B2 Test apparatus
Provided is a test apparatus in which a test for bacterial identification or antimicrobial susceptibility can be promptly determined. A division state of bacteria is monitored by performing microscopic observation of shapes and the number of the bacteria in each of wells in a culture plate for bacterial identification culture or an antimicrobial susceptibility test, and it is determined whether or not the bacteria grow in a stage shifted from an induction phase to a logarithmic phase, with reference to an image obtained through microscopic observation. In addition, determination performed based on turbidity in the related art may be combined with determination performed based on microscopic observation in which change and the like in the shapes of the bacteria are monitored. Accordingly, it is possible to realize a highly accurate test result.
US10900010B1 Incubator with air curtain
An incubator for cell and tissue culture under controlled atmospheric conditions has a primary air flow control device that forms a primary, preferably laminar flow, air veil across an opening that allows access to the cells or tissue cultures disposed within the incubator. Preferably, most if not all of the air in the primary (laminar flow) air veil is recirculated, and a secondary air flow control device is used that forms a secondary, preferably laminar flow, air veil between the primary (laminar flow) air veil and a user of the incubator.
US10900009B2 Method and device for automated removal of cells and/or cell colonies
The method comprises an automated removal of cells and/or cell colonies from a cell culture whilst executing a first detection step for selecting cells and/or cell colonies with reference to corporeal and/or physical parameters and detecting position data and storing the detected position data of the selected cells and/or cell colonies in a position database.In order to be able to select special cells and/or cell colonies having special properties from the detected cells and/or cell colonies, at least one second detection step for detecting at least one further parameter of the cells and/or cell colonies is then executed, comparative data from the data of the first and second detection step are created, cells and/or cell colonies are selected with reference to the comparative data and the position data from the position database are transferred to a harvesting unit.
US10900006B2 Method and apparatus to mitigate evaporation in high throughput measurements
A method and apparatus are disclosed for the collection of light scattered from a liquid sample contained within a multiwell plate for which evaporation from the wells is mitigated by the application of a barrier between the liquid sample and the environment. A vertical thermal gradient is applied across the vessel so that condensation is inhibited from forming on the interior surface of the barrier, thus permitting clear illumination of the sample for visual imaging, fluorescence studies and light scattering detection.
US10900005B2 Reservoir for food waste recycling appliance
The disclosure relates to a liquid reservoir for a food waste recycling appliance including a reservoir body with a hollow interior, a first arm portion, and a second arm portion, and at least partially bounding an interstitial space exterior of the reservoir body. A food waste through opening can be defined by an exterior surface of the reservoir body.
US10900004B2 Open loop additive material process and system for creating a human-habitable environment
Methods for producing hydrocarbon-based polymers and hydrocarbon-based polymeric structures that are capable of removing carbon dioxide from an ambient environment to produce breathable oxygen. The methods produce enclosed, solar-exposed polymeric structures capable of expanding in area through the reuse of at least a portion of the hydrocarbon-based polymers. As such, the method produces self-sustaining polymeric/hydrocarbon-based structures capable of in-situ resource harvesting and reuse to create a sustainable, habitable area. The methods can be used to create a habitable environment in otherwise harsh conditions, such as those associated with high concentrations of carbon dioxide and low pressure, without the need to use external, non-renewable resources, and instead using renewable, in-situ resources to improve the viability of habitation within the environment of the manufactured three-dimensional structures.
US10900003B2 Method for manufacturing instant egg/edible bird's nest soup with fermented glutinous rice
A method for manufacturing an instant egg/edible bird's nest soup with fermented glutinous rice, comprising the steps of preparing the fermented glutinous rice wine, separating the wine juice from the rice dregs, preparing the dehydrated egg droppings/edible bird's nest shreds, vacuum freeze drying and vacuum packing; the instant egg/edible bird's-nest soup with fermented glutinous rice manufactured according to the method of the present invention is easily portable, and can be immediately consumed after being brewed in hot water; the flavor of the brewed egg/edible bird's nest soup with fermented glutinous rice is fresh and sweet; the shape of the rice dregs and the egg droppings/edible bird's nest shreds can be perfectly kept, and the rice dregs and egg droppings/edible bird's nest shreds are soft and good-tasting.
US10899999B2 Solvent application in bottle wash using amidine based formulas
According to the invention, the compositions and methods provide for the complete removal of labels, synthetic glues and/or adhesives from a plurality of surfaces through the use of an aqueous or non-aqueous basic organic solvent and/or an amidine, optionally in combination with surfactants, chelants, acidulants and/or additional bottle wash additives. Beneficially, the compositions and methods are suitable for use at lower temperatures and pH conditions, along with under caustic-free and/or reduced caustic conditions to effectively remove such labels, synthetic glues and/or adhesives from a surface within less than about 30 minutes.
US10899996B2 Organic compounds
The use as fragrance ingredient of 4—methylene—2—(2—methylprop—1—enyl)—tetrahydropyran.
US10899994B2 Method for producing polyunsaturated fatty acid-containing composition
Provided is a method for producing a polyunsaturated fatty acid while suppressing deterioration of a silver salt solution. A method for producing a polyunsaturated fatty acid-containing composition, the method comprising: supplying a raw material solution comprising an alkyl ester of polyunsaturated fatty acid and an aqueous solution comprising a silver salt to a flow channel mixer to contact the raw material solution with the aqueous solution; and collecting the aqueous solution comprising the silver salt which has been contacted with the raw material solution, in which the supplying the aqueous solution comprising the silver salt to the flow channel mixer and the collecting the same are performed concurrently.
US10899991B2 Process for the preparation of a lubricant base stock comprising the selective thermal decomposition of plastic polyolefin polymer
The present invention relates to a process for the preparation of a lubricant base stock from the thermal decomposition of plastic polymer. The present invention provides a process for preparing a lubricant base stock from the thermal decomposition of plastic polyolefin polymer, the method comprising the steps of: i) introducing plastic polyolefin polymer into a thermal reaction zone of a vacuum pyrolysis reactor; ii) heating the plastic polyolefin polymer at sub-atmospheric pressure, wherein the temperature in the thermal reaction zone of the reactor is from 500° C. to 750° C., to induce thermal decomposition of the plastic polyolefin polymer and to form a thermal decomposition product effluent which comprises a major portion by weight of a C20 to C60 wax fraction; iii) condensing a vapour component of the thermal decomposition product effluent from the vacuum pyrolysis reactor; and iv) subjecting the C20 to C60 wax fraction of the thermal decomposition product to catalytic hydroisomerization in a hydroisomerization reactor in the presence of hydrogen to form the lubricant base stock; wherein the plastic polyolefin polymer comprises polyethylene and polypropylene in a polyethylene to polypropylene weight ratio of from 60:40 to 90:10.
US10899989B2 Amino acid grafted polymer with soot handling properties
The present disclosure relates to lubricant additives such as dispersants and dispersant viscosity modifiers including acyl peptide grafted polymers and lubricating oil compositions comprising such additives. The disclosure also relates to the use of lubricant compositions comprising the additives herein for improving the soot or sludge handling characteristics of an engine lubricant composition and while minimizing the deterioration of engine's elastomer compatibility.
US10899984B2 Fuel high temperature antioxidant additive
High temperature antioxidant additives and methods that improve a liquid fuel composition's thermal oxidative stability are disclosed. A liquid fuel composition may comprise a liquid fuel and a high temperature antioxidant additive. The high temperature antioxidant additive may comprise an aromatic carbocyclic ring that is monocyclic and comprises substituents comprising a hydroxyl group and an iminomethyl group positioned in an ortho relationship.
US10899977B2 Process and apparatus for hydrocracking with light fractionation column with three products
A process and apparatus for hydrocracking a hydrocarbon stream that strips a liquid hydrocracked stream in a stripping column to provide a stripping overhead stream and a stripped stream. The stripping overhead stream fractionated to provide a light fractionated overhead stream, a light fractionated intermediate stream and a light fractionated bottoms stream in a single light fractionation column omitting the need for a separate deethanizer column.
US10899976B2 Integrated process for maximizing recovery of liquid petroleum gas
An integrated process for maximizing recovery of LPG is provided. The process comprises providing a hydrocarbonaceous feed comprising naphtha, and a hydrogen stream to a reforming zone. The hydrocarbonaceous feed is reformed in the reforming zone in the presence of the hydrogen stream and a reforming catalyst to provide a reformate effluent stream. At least a portion of the reformate effluent stream and at least one stream comprising C6− hydrocarbons from one or more of a hydrocracking zone, an isomerization zone, and a transalkylation zone is passed to a debutanizer column of the reforming zone to provide a fraction comprising liquid petroleum gas (LPG) and a debutanizer column bottoms stream.
US10899975B2 Integrated process for maximizing recovery of hydrogen
An integrated process for maximizing recovery of hydrogen is provided. The process comprises: providing a hydrocarbonaceous feed comprising naphtha, and a hydrogen stream to a reforming zone, wherein the hydrogen stream is obtained from at least one of a hydrocracking zone, a transalkylation zone, and an isomerization zone. The hydrocarbonaceous feed is reformed in the reforming zone in the presence of the hydrogen stream and a reforming catalyst to provide a reformate effluent stream. At least a portion of the reformate effluent stream is passed to a debutanizer column of the reforming zone to provide a net hydrogen stream and a fraction comprising liquid petroleum gas (LPG). At least a portion of the net hydrogen stream is recycled to the reforming zone as the hydrogen stream.
US10899974B2 Light oil reflux heavies removal process
The invention relates to various nonlimiting embodiments that include methods, apparatuses or systems for processing natural gas comprising a heavies removal column processing natural gas and light oil reflux. The overhead stream goes to heavies treated natural gas storage. The heavies removal column reboiler bottoms stream product is input to a debutanizer column. The debutanizer column overhead lights are input to a flash drum where the bottoms is pumped through a heat exchanger as a light oil reflux input to the heavies removal column, while the debutanizer reboiler bottoms product is stored as stabilized condensate. Alternatively, debutanizer column overhead lights are sent to heavies treated gas storage and the bottoms stream product goes to a depentanizer column, the overhead lights are pumped through a heat exchanger as a light oil reflux input to the heavies removal column, while the depentanizer reboiler bottoms product is stabilized condensate.
US10899972B1 Fluid catalytic cracking of petroleum oil with reduced emissions
A method for fluid catalytic cracking (FCC) of petroleum oil feedstock includes reacting the petroleum oil feedstock with a catalyst mixture in a reaction zone of an FCC unit to obtain a product stream including desulfurized hydrocarbon product, unreacted petroleum oil feedstock, and spent catalyst. During the reacting a process control system develops a process model based on data collected during the reacting, the process model characterizing a relationship among the feed rate of the base cracking catalyst, the feed rate of the FCC additive, the operating conditions, the composition of the product stream, and emissions from the reaction; and one or more of (i) a target feed rate of the base cracking catalyst, (ii) a target feed rate of the FCC additive, and (iii) one or more target operating conditions of the reaction in the reaction zone to reduce the emissions from the FCC unit and to increase a yield of the desulfurized hydrocarbon product in the product stream are determined.
US10899970B2 Pyrolysis product compression
The invention relates to the compression of a pyrolysis product to facilitate light olefin separation. The pyrolysis product is produced in a pyrolysis reaction. A power generator produces a first shaft power and a second shaft power. The pyrolysis product is compressed using at least part of the first shaft power and at least part of the second shaft power.
US10899968B2 Method for producing recycled material, and tire and method for producing tire
There is provided a method for producing a recycled material, whereby a recycled material can be efficiently obtained from a tire. The method for producing a recycled material according to the present invention includes a step of subjecting a tire to a gasification treatment to generate a gas containing a C1 gas from the tire, and a step of obtaining a recycled material containing at least one species selected from the group consisting of isoprene, butadiene, a butanediol compound, a butanol compound, a butenal compound, succinic acid, and polymers of these compounds by using the gas containing the C1 gas.
US10899963B2 Light-emitting structure, optical member having the light-emitting structure, light-emitting device, and liquid crystal display apparatus
A light-emitting structure in accordance with the present disclosure includes inorganic nano-particles; ligands coordinated to surfaces of the inorganic nano-particles, wherein each of the ligands contains an acrylic polymer. Further, the present disclosure provides an optical member, a light-emitting device, and a liquid crystal device including the light-emitting structure.
US10899961B2 Quantum dots with stabilizing fluorochemical copolymers
Disclosed are quantum dots and quantum dot articles stabilized by a fluorochemical copolymer having pendent arsine, stibine or phosphine stabilizing groups; and pendent fluorochemical groups.
US10899958B2 Liquid gas treatment fluids for use in subterranean formation operations
The embodiments of the present disclosure relate to increasing fracture network complexity within a subterranean formation using a plurality of fluid stages where one or more of such fluid stages utilizes a liquid gas treatment fluid. The embodiments described herein allow creation or extension of a dominant fracture and branch fractures extending therefrom at one or both of the near-wellbore region and/or the far-field region of a fracture network, thereby enhancing fracture network complexity.
US10899957B2 Additives to minimize viscosity reduction for guar/borate system under high pressure
A composition for use as a pressure-tolerant dual-crosslinker gel in a fracturing fluid that comprises polymer, the polymer operable to increase the viscosity of a fluid; boron-containing crosslinker, the boron-containing crosslinker operable to crosslink the polymer; and a transition metal oxide additive, the transition metal oxide additive operable to crosslink the polymer.
US10899948B2 Adhesive sheet
The adhesive sheet for bonding an unvulcanized rubber to a metal, including a base cloth layer impregnated with a solvent dispersed type vulcanization adhesive having reactivity with the unvulcanized rubber; and an adhesive layer having reactivity with the metal.
US10899942B2 Process for producing a coated pipe
The present invention deals with a process for producing a coated pipe. The process comprises (i) homopolymerising ethylene or copolymerising ethylene and an α-olefin comonomer in a first polymerisation step in the presence of a polymerisation catalyst to produce a first ethylene homo- or copolymer having a density of from 940 to 980 kg/m3 and a melt flow rate MFR2 of from 1 to 2000 g/10 min; (ii) homopolymerising ethylene or copolymerising ethylene and an α-olefin comonomer in a second polymerisation step in the presence of a first ethylene homo- or copolymer to produce a first ethylene polymer mixture comprising the first ethylene homo- or copolymer and a second ethylene homo- or copolymer, said first ethylene polymer mixture having a density of from 940 to 980 kg/m3 and a melt flow rate MFR2 of from 10 to 2000 g/10 min; (iii) copolymerising ethylene and an α-olefin comonomer in a third polymerisation step in the presence of the first ethylene polymer mixture to produce a second ethylene polymer mixture comprising the first ethylene polymer mixture and a third ethylene copolymer, said second ethylene polymer mixture having a density of from 915 to 965 kg/m3, preferably from 930 to 955 kg/m3 and a melt flow rate MFR5 of from 0.2 to 10 g/10 min; (iv) providing a pipe having an outer surface layer; (v) applying a coating composition onto the pipe outer surface layer to form a top coat layer, wherein the coating composition comprises the second ethylene polymer mixture.
US10899941B2 Yellow ink composition for nonaqueous inkjet
An object of the invention is to provide a yellow ink composition for nonaqueous inkjet that achieves excellent density and weather resistance on printed matters whose printing surface is constituted by a polyvinyl chloride polymer, ethylene-vinyl acetate copolymer, or other vinyl polymer or the like, while also ensuring excellent discharge stability, even in a high-speed printing mode. To this end, a yellow ink composition for nonaqueous inkjet is provided that contains, as the pigment, C. I. Pigment Yellow 150 and C. I. Pigment Yellow 83 at a ratio by mass, calculated by “C. I. Pigment Yellow 150/C. I. Pigment Yellow 83,” of 5/5 to 9/1, and further contains a pigment dispersant, a resin, and an organic solvent.
US10899937B2 Hydrogen-bonding surfaces for ice mitigation
Various embodiments provide ice mitigating surface coatings and methods for applying ice mitigating surface coatings. Various embodiment ice mitigating surface coatings may be formed by hydrolysis of one or more substituted n-alkyldimethylalkoxysilanes terminated with functionalities having the following characteristics with respect to water: 1) non-polar interactions; 2) hydrogen bonding through donor and acceptor interactions; or 3) hydrogen bonding through acceptor interactions only. The substituted n-alkyldimethylalkoxysilanes of the various embodiments may include methyl terminated species, hydroxyl terminated species, ethylene glycol terminated species, and methoxyethylene glycol terminated species. Various embodiment ice mitigating surface coatings may be applied to metal surfaces, such as aluminum surfaces. Various embodiment substituted n-alkyldimethylalkoxysilanes may have an aliphatic chain that is saturated and liner or branched or that is partially unsaturated and liner or branched.
US10899936B2 Anti-smudge and anti-graffiti compositions
Polyurethane-based and epoxy-based coating compositions are described that provide coatings and adhesives that are clear, amphiphobic and durable. Both water and hexadecane readily slide off these surfaces without leaving a residue. Coatings with thicknesses ranging from about 10 nm to about 10 μm exhibited excellent transmittance properties. Such films exhibited durability against abrasion, ink-resistance, anti-graffiti, anti-fingerprint, and strong adhesion to glass surfaces. The coatings are applicable to electronic devices, fabrics, glass, etc. to prepare optically clear, stain-resistant, and smudge-resistant surfaces.
US10899932B2 Non-amphoteric, quaternisable and water-soluble polymers for modifying the surface charge of solid particles
The present invention relates to particles based on inorganic, organic compounds, sulfur and/or diamond, coated with a nonampholytic, quaternizable polymer which is water-soluble at 20° C., and also to their use. The invention likewise pertains to a method for depositing these disperse particles in a metallic phase on the surface of a substrate.
US10899928B2 Enhanced alkyl ester containing oil compositions and methods of making and using the same
Vegetable oil compositions, as an example, corn oil, having an elevated lower alkyl ester content above about 7% weight percent of the total weight of the oil composition, and uses thereof are provided.
US10899925B2 Scratch-resistant polycarbonate compositions having good thermal stability
The patent application relates to compositions comprising A) 50% to 90% by weight of at least one polymer selected from the group consisting of aromatic polycarbonate, aromatic polyestercarbonate and polyester, B) 5% to 40% by weight of at least one rubber-modified graft polymer, C) 1% to 20% by weight of fused silica having an average particle size d50 of 1.0 to 10.0 μm and a content of metal oxides≤2% by weight based on component C, D) 0% to 20% by weight of at least one additive distinct from component C, and to the use of the compositions for the production of moulded articles, and to the moulded articles themselves.
US10899920B2 Methods for forming high shrink wrap label sleeves
Methods for forming high shrink wrap label sleeves directly from a roll are disclosed herein. A seaming agent is applied to the label, where the trailing edge will overlap the leading edge to form a seam. The seaming agent is then exposed to radiation to cure the seaming agent and form a sleeve. The label comprises a film with at least one external layer that has a Hildebrand solubility parameter, and the seaming agent includes a component having a Hildebrand solubility parameter that is within 2.2 MPa1/2 or within 4.4 calories1/2·cm−3/2 of the Hildebrand solubility parameter of the external layer of the film. The seaming agent also has a viscosity of at least 1 centipoise and less than 1000 centipoise when measured at any temperature between ambient temperature and 60° C.
US10899919B2 4- and 5-substituted 1,2,3-triazole, and regioisomer mixtures thereof, modified polymers
Provided are novel 4- and 5-substituted 1,2,3-triazoles, and regioisomer mixtures thereof, modified polymers, wherein the substituted 1,2,3-triazoles are modified by reaction with a modifying polymer (maleic anhydride based polymer). Depending upon the ratio of the substituted 1,2,3-triazole to the maleic anhydride based polymer employed, the resulting modified polymers can provide maleic anhydride based polymers that are partially or fully reacted with the substituted 1,2,3-triazoles. The resulting modified polymers may be partially or fully opened to provide amic acids, carboxylic acids, carboxylic acidic salts, imides, or esters. The novel 4- or 5-substituted 1,2,3-triazoles, and regioisomer mixtures thereof, modified polymers can be converted to a wide variety of useful polymers and may be employed in a wide variety of compositions. An example of a modified polymer may be represented by the structure: formula: (1) wherein m, n, and q are defined herein.
US10899917B2 Fluoroelastomer composition
The invention pertains to a dual cure fluoroelastomer composition including certain nitrile-containing fluoropolyether compounds, able to provide for cured parts having improved thermal and water vapour resistance, to a method of curing the same and to cured articles obtained therefrom.
US10899911B2 Reactive flame retardants for flexible polyurethane foams
The present invention provides dialkyl phosphorus-containing compounds, namely reactive mono-hydroxyl-functional dialkyl phosphinates, serving as highly efficient reactive flame retardants in flexible polyurethane foams. The invention further provides fire-retarded polyurethane compositions comprising said the reaction product of the mono-hydroxyl-functional dialkyl phosphinates with polyol and isocyanate foam forming components.
US10899909B2 Polycarbonate compositions with improved stabilisation
The invention relates to compositions containing(A) at least one polymer selected from the groups of aromatic polycarbonates and aromatic polyester carbonates and(B) at least one Bronsted-acidic compound, such as ethylenediaminetetraacetic acid (EDTA),and also relates to a process for producing compositions using components (A), (B) and optionally further components, wherein at least one of the employed components is alkaline or contains alkaline constituents, to compositions obtained by this process and to the use of the compositions for producing molded articles and to the molded articles themselves.
US10899907B2 On demand radiation induced constructive and deconstructive chemical reactions
A method is provided for decomposition of a polymeric article, wherein the polymeric article contains a polymer and one or more energy modulation agents, by applying an applied energy to the polymeric article, wherein the one or more energy modulation agents convert the applied energy into an emitted energy sufficient to cause bond destruction within the polymer.
US10899905B2 Millable silicone rubber composition, millable silicone rubber sponge, and method for producing said sponge
A method for producing a millable silicone rubber sponge is a method for producing a millable silicone rubber sponge with an open cell ratio of not lower than 20%, comprising: performing a heat treatment on a silicone rubber composition at 200° C. or higher, the silicone rubber composition containing: (A) an organopolysiloxane having at least two alkenyl groups in one molecule and a polymerization degree of not lower than 3,000; (B) a reinforcing silica; (C) thermally expandable microcapsules exhibiting an expansion starting temperature of 90 to 150° C., and contracting from a maximum expansion volume by 20% or more when heated at 200° C. for 5 min; (D) a curing agent; and (E) an open cell-forming agent which is a solid high temperature decomposition-type organic foaming agent having a decomposition starting temperature of not lower than. 180° C., and starting to decompose after the component (A) is cured.
US10899903B2 Scalable manufacturing method of property-tailorable polyurea foam
The scope of this invention is to disclose the method of foaming a superior impact mitigation material, namely semi-closed cell hybrid polyurea foam, using scalable manufacturing process that is geometry-independent and allows for greater control of the resulting foam properties. while the process discussed herein, can be easily used to make complex geometries (e.g., padding foam for helmets, outsoles for walking and running shoes, body armors or other protection applications.
US10899896B2 Reinforcing fiber bundle and molding material
Disclosed are: a reinforcing fiber bundle with excellent mechanical property and handling property, which contains a propylene-based resin (A), a propylene-based resin (B) comprising at least a carboxylic acid salt bonded to the polymer chain, and a reinforcing fiber (C) wherein the propylene-based resin (A) comprises more than 70% by mass but not more than 100% by mass of a component (A-1) having a weight average molecular weight of 150,000 or more, the amount of the propylene-based resin (B) is 3 to 50 parts by mass per 100 parts by mass of the propylene-based resin (A), and the total content rate of the propylene-based resin (A) and the propylene-based resin (B) is 0.3 to 5% by mass in the whole reinforcing fiber bundle; and a molding material comprising the reinforcing fiber bundle and a matrix resin.
US10899895B2 Methods for manufacturing coated metal nanoparticles and a composite material comprising same, use of such a material and device comprising same
A method for preparing coated metal nanoparticles, each nanoparticle comprising a core constituted of at least one metal M and a layer constituted of at least one polymer, the layer coating the metal core. The method comprises the steps: (a1) preparing a solution A comprising the at least one metal M in the form of cations Mn+, n being an integer comprised between 1 and 3, each metal M being a transition metal of atomic number comprised between 21 and 30, a polyol, and a noble metal salt; (a2) preparing a solution B comprising at least one organic monomer of the at least one polymer, in an organic solvent; (b) mixing solutions A and B, this mixture being heated to the boiling temperature of the polyol; and (c) recovering the coated metal nanoparticles.
US10899893B2 Aminosilane-modified colloidal silica dispersion and method of manufacturing same
The aminosilane-modified colloidal silica dispersion contains colloidal silica particles having surfaces to which there are bound a first silyl group represented by the following formula (1): R1aSi(OR2)3-aO— and a second silyl group represented by the following formula (2): R3bSi(OR4)3-bO— and, as a dispersion medium, a mixed solvent formed of a polar solvent S1 having a dielectric constant at 20° C. of 15 or higher and lower than 60 and a non-polar solvent S2 having a dielectric constant at 20° C. of 1 or higher and lower than 15, at a mass ratio (S1/S2) of 0.3 to 6.
US10899892B2 Copolymerized high temperature bonding component
A method for preparing a bonding component comprises mixing a first solution comprising an organofluorine monomer unit with a second solution comprising an organosilicon monomer unit to form, in-situ, a copolymer solution comprising a copolymer of an organofluorine polymer and an organosilicon polymer based on the organofluorine monomer unit and the organosilicon monomer unit. The method further comprises depositing the copolymer solution onto a body to form a film of the copolymer, and curing the film of the copolymer.
US10899891B2 Reactive polysiloxane and polymerizable composition comprising same
A polymerizable composition includes 100 parts by mass of a reactive polysiloxane being a polycondensation product of an alkoxy silicon compound including at least an alkoxy silicon compound of formula [1], and 10 to 500 parts by mass of a polymerizable compound having at least one polymerizable double bond. (X is a phenyl group having at least one substituent having a polymerizable double bond, a naphthyl group having at least one substituent having a polymerizable double bond, a biphenyl group having at least one substituent having a polymerizable double bond, or a phenanthryl group having at least one substituent having a polymerizable double bond, Ar1 is a condensed ring hydrocarbon group having two or more benzene ring structures, or a hydrocarbon ring assembly group in which two or more aromatic rings are directly bonded through a single bond, and R1 is methyl group, ethyl group, or isopropyl group).
US10899889B2 Aromatic polysulfone and aromatic polysulfone composition
The invention provides an aromatic polysulfone including an aromatic polysulfone having at least one highly polar functional group at its terminus, wherein in the aromatic polysulfone, an area of a signal attributed to the aromatic polysulfone having a highly polar functional group with respect to a total area of all signals attributed to the aromatic polysulfone in a chromatogram obtained by measurement through a gel permeation chromatography method under the following conditions is 0.1% or more and 11% or less, wherein the sample injection volume is 5 μL, column is “Shodex KF-803” manufactured by Showa Denko K.K., column temperature is 40° C., eluent is N,N-dimethylformamide, eluent flow rate is 0.5 mL/min, detector is ultraviolet-visible spectrophotometer (UV), and detection wavelength is 277 nm.
US10899887B2 High heat copolyimides, articles prepared therefrom, and methods of manufacturing copolyimide articles
A copolyimide includes the reaction product of an aromatic dianhydride component including a substituted or unsubstituted pyromellitic dianhydride or a functional derivative thereof and an aromatic bis(ether phthalic anhydride) or a functional derivative thereof, and an organic diamine component comprising a substituted or unsubstituted phenylene diamine and a diaminodiphenyl sulfone. Articles and compositions including the copolyimides and methods of manufacturing a polyimide film are also described.
US10899886B2 Polyimide precursor solution and method for producing same
The present invention provides a polyimide film which, by having a fluorine structure adopted into a rigid polyamide chain structure, exhibits not only superb heat resistance but also enhanced optical properties. Additionally, the polyimide according to the present invention, by having the particular structure, exhibits excellent transparency, heat-resistance, mechanical strength and flexibility, and thus can be utilized in a variety of functions such as an element substrate, display cover substrate, optical film, integrated circuit (IC) package, adhesive film, multi-layered flexible printed circuit (FPC), tape, touch panel, and protective film for optical disks.
US10899881B1 Polyester modification method
The subject invention provides a means for modifying existing polyester polymers to optimize characteristics for solid state polymerization and for utilization in a wide array of specific applications. For instance, the modification technique of this invention may be used to adjust the melting point, crystallization temperature (either from the solid or on cooling from the melt), glass transition temperature, natural stretch ratio, barrier properties, melt strength, and/or solid state polymerization characteristic of the polyester. Application of the instant invention could result in a polymer with substantially different physical properties, potentially allowing its use in heretofore high cost, specialty applications. A further advantage of the invention is that recycled polymer may be modified to broaden its potential uses into more demanding higher performance applications.
US10899877B2 Poly(ester-carbonate)s, articles formed therefrom, and methods of manufacture
A poly(carbonate-ester) copolymer including carbonate units of the formula (I); and ester units of the formula (II) wherein: T is a C2-20 alkylene, a C6-20 cycloalkylene, or a C6-20 arylene; and R1 and J are each independently a bisphenol A divalent group, or a phthalimidine divalent group or a third divalent group of the formula (III), (IV), (V), (VI) or (VII) wherein Xa is a C6-12 polycyclic aryl, C3-18 mono- or polycycloalkylene, C3-18 mono- or polycycloalkylidene, -(Q1)x-G-(Q2)y- group wherein Q1 and Q2 are each independently a C1-3 alkylene, G is a C3-10 cycloalkylene, x is 0 or 1, and y is 1, provided that the at least one bisphenol A divalent group, at least one phthalimidine divalent group, and at least one third divalent group are present in the poly(carbonate-ester) copolymer.
US10899873B2 Process for preparing epoxy resins
An epoxy oligomerization catalyst can be employed to prepare an epoxy resin employing a method including admixing a first epoxy resin having a first epoxy equivalent weight of from about 100 to about 600 with a diphenolic compound, and a catalyst, thereby forming a second epoxy resin having a second epoxy equivalent weight of from about 200 to about 10,000; wherein the catalyst is a guanidinium catalyst. The second equivalent weight is greater than the first equivalent weight.
US10899872B2 Highly soluble modified epoxy resin composition
An epoxy resin composition in a liquid or solid state having excellent solubility and having high preservation stability. A modified epoxy resin composition including: Compound A containing tris-(2,3-epoxypropyl)-isocyanurate having 1 to 3 glycidyl group(s) in a molecule substituted with a functional group(s) of Formula (1): in which R1 and R2 are each independently an alkyl group, an alkenyl group, an alkynyl group, an aryl group, an aralkyl group, a heterocyclic group; or a halogenated derivative, an aminated derivative, or a nitrated derivative of these groups; and Compound B containing tris-(2,3-epoxypropyl)-isocyanurate, wherein tris-(2,3-epoxypropyl)-isocyanurate of Compound A before the substitution and tris-(2,3-epoxypropyl)-isocyanurate of Compound B comprise 2% by mass to 15% by mass of β-type tris-(2,3-epoxypropyl)-isocyanurate and a remaining percentage of α-type tris-(2,3-epoxypropyl)-isocyanurate based on a total mass of Compound A before the substitution and Compound B.
US10899871B2 Phosphorous containing epoxy resins and process for synthesis
The present invention provides epoxy resin compounds comprising a high phosphorus and oxazolidone content, methods to prepare these epoxy resin compounds, curable compositions comprising these epoxy resins, and cured epoxy resin compounds by curing the curable epoxy resin compounds comprising a high phosphorus and oxazolidone content.
US10899869B2 Glycerol containing polyurethanes and polyurethane nanocomposites
The present invention generally relates to polyurethanes and polyurethane nanocomposites having improved mechanical, rheological, and thermal properties over ordinarily produced polyurethanes and polyurethane nanocomposites. Such polyurethanes and polyurethane nanocomposites include very small amounts of a small chain diol, such as glycerol, and more specifically, between 0.01 and 4 weight percent of the small chain diol, based on the total polymer composition.
US10899868B2 Methods for producing footwear with materials having multiple mechanisms of hardening
A method of forming a three-dimensional object, wherein said three-dimensional object is a footwear sole, heel, innersole or midsole, is described. The method may use a polymerizable liquid, or resin, useful for the production by additive manufacturing of a three-dimensional object, comprising a mixture of (i) a light polymerizable liquid first component, and (ii) a second solidifiable component that is different from said first component.
US10899864B2 Polar modifier systems for high vinyl block copolymerization
Polar modifier systems based on a blend of DTHFP, ETE, TMEDA, DMTHFMA and/or functionally similar compounds with BDMAEE and SMT are used to make block copolymers having high levels of pendant vinyl double bond repeat units, which is through highly selective 1,2-bond butadiene addition, low vinylcyclopentane formation, unimodal narrow molecular weight distribution, and a low level of randomized co-monomer repeat units. The block copolymers have very high levels of 1,2-vinyl content and high 3,4-vinyl bond addition of the conjugated diene monomer and low vinylcyclopentane content. The polar modifier systems provide a fast polymerization rate, with a unimodal narrow molecular weight distribution. The polar modifier systems allow operation at a higher temperature than in prior art systems, which reduces cooling requirements.
US10899862B2 Hydrophobic intraocular lens
A hydrophobic intraocular lens (IOL) with excellent non-glistening characteristics, high Abbe number, excellent mechanical properties comprising at least one copolymer comprising: (a) a first monomeric subunit comprising a polymerized (meth)acrylate group and at least one alkoxyalkoxyalkyl side group, (b) a second monomeric subunit different from the first monomeric subunit comprising a polymerized (meth)acrylate group, at least one side group comprising (i) an aryloxy moiety with at least one halogen, and (ii) an aliphatic carbon moiety linking the aryloxy moiety with the polymerized (meth)acrylate group, wherein the aliphatic carbon moiety comprises at least one hydroxyl substituent.
US10899845B2 Anti-variant Fc-region antibodies and method of use
The invention provides anti-variant Fc-region antibodies which specifically bind to an antibody that has the mutation P329G or the mutations P329G/L234A/L235A or the mutations I253A/H310A/H435A in the Fc-region, and methods of using the same.
US10899842B2 4-1BB binding proteins and uses thereof
Binding proteins that specifically bind to 4-1BB (CD137) are disclosed. More specifically, antibodies that specifically bind to human 4-1BB are disclosed. These binding proteins may be used to treat or to prevent diseases such as cancers by altering the levels or activities of 4-1BB.
US10899838B2 Antibody which is directed against galectin-9 and is an inhibitor of the suppressor activity of regulatory T lymphocytes
The invention relates to an antibody which is directed against galectin-9 and is an inhibitor of the suppressor activity of regulatory T lymphocytes, and also to the use of this antibody for the treatment of diseases associated with the suppressor activity of regulatory T lymphocytes, in particular the treatment of cancer.
US10899832B2 Treatment of fibrosis with interleukin-11 receptor alpha antibody
Aspects of the disclosure relate to the treatment, prevention or alleviation of conditions such as fibrosis in a subject. In some embodiments, the treatment, prevention or alleviation of fibrosis in a subject through the administration of an agent capable of inhibiting the action of Interleukin 11 (IL-11) is disclosed.
US10899831B2 Method of reducing the level of non-GM-CSF cytokines/chemokines in immunotherapy-related toxicity
Methods for reducing relapse rate or preventing occurrence of tumor relapse in a subject treated with immunotherapy, in an absence of an incidence of immunotherapy-related toxicity or in a presence of immunotherapy-related toxicity. Methods for reducing a level of a cytokine or chemokine other than GM-CSF in a subject having an incidence of immunotherapy-related toxicity, the methods comprising administering a recombinant GM-CSF antagonist to the subject. Methods for treating or preventing immunotherapy-related toxicity in a subject, the methods comprising administering to the subject chimeric antigen receptor-expressing T-cells (CAR-T cells), the CAR-T cells having a GM-CSF gene knockout (GM-CSFk/o CAR-T cells), and a recombinant hGM-CSF antagonist.
US10899828B2 Optimized variants of anti-vegf antibodies and methods of use thereof in treatment
The present invention provides anti-VEGF antibodies and compositions that include anti-VEGF antibodies (e.g., antibody conjugates, fusion proteins, and polymeric formulations), and uses thereof, for example for treatment of disorders associated with pathological angiogenesis. The present invention also provides methods of identifying antibody variants with improved properties, for example, enhanced binding affinity, stability, pharmacokinetics, and/or expression.
US10899825B2 Flavivirus neutralizing antibodies and methods of use thereof
The present invention provides antibodies that neutralize flavivirus and methods of use thereof. These antibodies are derived from mAbl 1 which recognizes West Nile virus E protein and is cross-reactive with members of the flavivirus family, including Denge virus. The antibodies of the present invention prevent antibody-dependent enhancement of a viral infection by having a modified Fc region that does not bind to the Fcy receptor. The invented antibody is used to treat flaviviral infections and symptoms thereof.
US10899823B2 Programmable protein circuits in living cells
Some embodiments of the systems, methods and compositions provided herein relate to a compound protease. In some embodiments, the compound protease includes a protease domain and a cut site for another enzyme. In some embodiments, the compound protease includes an association domain. In some embodiments, the compound protease is part of a protein circuit.
US10899821B2 Method of treating neoplasia with a multimeric IL-15 soluble fusion molecule
The present invention features compositions and methods featuring ALT-803, a complex of an interleukin-15 (IL-15) superagonist mutant and a dimeric IL-15 receptor α/Fc fusion protein useful for enhancing an immune response against a neoplasia (e.g., multiple myeloma, melanoma, lymphoma) or a viral infection (e.g., human immunodeficiency virus).
US10899815B2 Compositions and methods of using islet neogenesis peptides and analogs thereof
The invention provides peptides and analogs of INGAP and HIP peptides. The peptides and analogs can be used in methods for treating various diseases and conditions. Such diseases and conditions can include impaired pancreatic function, treating a metabolic disease, for example, diabetes, both type 1 and type 2 diabetes, islets induction, expansion and proliferation for transplantation, promoting neuroprotection or nerve regeneration, promoting liver regeneration or inhibiting inflammation.
US10899814B2 Immunotherapy with A*01 restricted peptides and combination of peptides against cancers and related methods
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US10899812B2 Immunotherapy with A*01 restricted peptides and combination of peptides against cancers and related methods
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US10899809B2 Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC, SCLC and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US10899808B2 Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC, SCLC and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US10899802B2 Neisseria meningitidis compositions and methods thereof
In one aspect, the invention relates to a composition including a first polypeptide having the sequence set forth in SEQ ID NO: 1 and a second polypeptide having the sequence set forth in SEQ ID NO: 2. In one embodiment, the composition includes about 120 μg/ml of a first polypeptide including the amino acid sequence set forth in SEQ ID NO: 1, 120 μg/ml of a second polypeptide including the amino acid sequence set forth in SEQ ID NO: 2, about 2.8 molar ratio polysorbate-80 to the first polypeptide, about 2.8 molar ratio polysorbate-80 to the second polypeptide, about 0.5 mg/ml aluminum, about 10 mM histidine, and about 150 mM sodium chloride. In one embodiment, a dose of the composition is about 0.5 ml in total volume. In one embodiment, two-doses of the composition induce a bactericidal titer against diverse heterologous subfamily A and subfamily B strains in a human.
US10899800B2 Stabilized soluble pre-fusion RSV F polypeptides
Described are stable pre-fusion respiratory syncitial virus (RSV) F polypeptides, immunogenic compositions comprising the polypeptides and uses thereof for the prevention and/or treatment of RSV infection.
US10899795B2 Modified epitopes for boosting CD4+ T-cell responses
The present invention relates to immunogenic peptides comprising a T-cell epitope. Said peptides are modified such that CD4+ T-cell responses are obtainable that are much stronger than the CD4+ T-cell responses obtained with the same peptides not comprising said modification. In particular, the modification is the addition of a cysteine, insertion of a cysteine or mutation into a cysteine of a residue at a position adjacent to but outside the MHC-binding site of the peptide. Further disclosed are the use of such modified peptides in treating, suppressing or preventing diseases such as infectious or allergic diseases and autoimmune diseases, in preventing or suppressing graft rejection, or in the eradication of tumor cells.
US10899794B2 Cell epitopes and combination of cell epitopes for use in the immunotherapy of myeloma and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer, in particular myeloma. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US10899793B2 Melanocortin ligands and methods of use thereof
Certain embodiments of the invention provide a compound of formula (I): R1—C(═O)—W—X—Y—Z—N(R2)2  (I) or a salt thereof, wherein R1, R2, W, X, Y and Z are as defined herein, as well as methods of use thereof.
US10899792B2 Production method for insoluble recombinant protein aggregate
An object of the present invention is to provide a method for efficiently separating insoluble bodies of a recombinant protein from a recombinant cell expressing a target recombinant protein as insoluble bodies in the cell. The present invention provides a method for producing a recombinant protein aggregate by separating insoluble bodies of a recombinant protein from a recombinant cell expressing the recombinant protein as insoluble bodies in the cell, including disrupting the recombinant cell, aggregating the insoluble bodies of the recombinant protein, and separating the resulting aggregate.
US10899790B2 Method for modifying T cell population
Provided are: a compound represented by formula (I); a retinoid metabolic pathway inhibitor comprising the same; an agent for increasing the ratio of memory T cells; a prophylactic and/or therapeutic agent for cancer or an infectious disease; a cancer immunotherapeutic adjuvant; an immunopotentiator; and a method for preparing a T cell population wherein the ratio of memory T cells is increased, said method comprising using the compound of formula (I).
US10899788B2 Cyclic phosphate substituted nucleoside compounds and methods of use thereof for the treatment of viral diseases
The present invention relates to Cyclic Phosphate Substituted Nucleoside Compounds of Formula (I), and pharmaceutically acceptable salts thereof, wherein in A, B, R1, R2, R3, Q and V are as defined herein. The present invention also relates to compositions comprising a Cyclic Phosphate Substituted Nucleoside Compound, and methods of using the Cyclic Phosphate Substituted Nucleoside Compounds for treating or preventing HCV infection in a patient.
US10899787B2 Cytarabine prodrug nucleoside cyclic phosphate compound based on liverspecific delivery and use
Disclosed are an anticancer prodrug nucleoside cyclic phosphate compound based on liver-specific delivery (LSD) technology and the use thereof, in particular, provided are a compound of formula (I) and an isomer, a pharmaceutically acceptable salt, a hydrate, a solvate and a corresponding pharmaceutical composition thereof, and the use of the compound alone or in combination with other anticancer drugs against cancer, especially in treating hepatic carcinoma (HCC).
US10899785B2 Aminoglycoside derivatives and uses thereof in treating genetic disorders
Novel aminoglycosides, represented by Formulae Ia and Ib, as defined in the instant specification, designed to exhibit stop codon mutation readthrough activity, are provided. Also provided are pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic diseases and disorders, such as diseases and disorders associated with stop codon mutations.
US10899782B2 Separation of oligosaccharides from fermentation broth
The present invention relates to a method for separating sialylated oligosaccharides from a fermentation broth in which they are produced by a genetically modified microorganism The separation comprises the steps of: i) ultrafiltration; ii) nano-filtration; iii) optionally, activated charcoal treatment; and iv) treatment with strong anion and/or cation exchange resin.
US10899779B2 Method for manufacturing amino group-containing organosilicon compound
A method for manufacturing an amino group-containing organosilicon compound of the following formula (1): wherein each R1 independently represents an alkyl group having 1 to 10 carbon atoms, etc., each of R2 and R3 represents a functional group of the following formula (4), etc., m represents an integer of 1 to 3, and n represents an integer of 1 to 12, wherein an asterisk * represents a bond with an adjacent atom, p represents an integer of 1 to 12, and q represents an integer of 1 to 10, the method comprising: (A) reacting an amine compound of the following formula (2): wherein R2 and R3 mean the same as above with a halogen group-containing organosilicon compound of the following formula (3): wherein X represents a chlorine atom, etc., and R1 and n mean the same as above; (B) removing an amine hydrohalide produced in the step (A), by liquid-liquid separation; and (C) neutralizing an organic layer obtained in the step (B), using a base which amounts 0.1 to 0.95 mol equivalent, relative to a halide ion contained in the organic layer.
US10899778B2 Silane compound, rubber composition and tire
Disclosed are a silane compound of the general formula (1) described below, as well as a rubber composition including the same, and a tire. A silane compound of the general formula (1) is useful because of its ability to provide a silane compound comprising: a reactive functional group having a high reactivity with an organic polymer material such as rubber, and having a low polarity; and a hydrolyzable group having a high reactivity with an inorganic material such as silica or glass. The symbols in the formula are defined in the specification.
US10899776B2 Antiviral and antibacteria agents based on quaternary ammonium compound complexed with boric acid and its derivatives
The present document describes compounds resulting from the complexation of quaternary ammonium compounds with boric acid and/or its derivatives, and methods of making the same, and methods of using the same for the treatment of pathogenic infections.
US10899771B2 Process for making beta 3 agonists and intermediates
The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency.
US10899760B2 Processes for preparing an FGFR inhibitor
Disclosed herein are processes for preparing 8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one and FGFR inhibitor, as well as polymorphs and/or salt forms thereof.
US10899756B2 Phosphodiesterase inhibitors and uses thereof
The invention provides for novel benzonaphthyridine derivatives and compositions comprising novel benzonaphthyridine derivatives. In some embodiments, the compounds are phosphodiesterase inhibitors. The invention further provides for methods for inhibition of phosphodiesterase comprising contacting phosphodiesterase with novel benzonaphthyridine derivatives or compositions comprising novel benzonaphthyridine derivatives. The invention further provides for methods for treatment of neurodegenerative diseases, increasing memory or long term potentiation with novel benzonaphthyridine derivatives or compositions comprising novel benzonaphthyridine derivatives. In some embodiments, the phosphodiesterase is PDE5.
US10899749B2 Preparation of sufentanil citrate and sufentanil base
Provided herein are processes for forming sufentanil citrate from sufentanil base. One process comprises forming sufentanil citrate in the presence of a polar non-aqueous solvent. Other processes comprise forming sufentanil citrate in the presence of water.
US10899748B2 Anti-proprotein convertase subtilisin kexin type 9 (anti-PCSK9) compounds and methods of using the same in the treatment and/or prevention of cardiovascular diseases
Disclosed are compounds that modulate the physiological action of the proprotein convertase subtilisin kexin type 9 (PCSK9), as well as therapeutic methods for use of such compounds to reduce LDL-cholesterol levels and/or for the treatment and/or prevention of cardiovascular disease (CVD), including treatment of hypercholesterolemia.
US10899747B2 Biaryl piperidine amide compounds and methods of use thereof
The present application is directed to biaryl piperidine amide compounds, or pharmaceutically acceptable salts, solvates, and prodrugs thereof, and methods of use thereof.
US10899745B2 Process for the preparation of 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide
The invention relates to an improved process for synthesizing 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide of the formula: [INSERT CHEMICAL STRUCTURE HERE] Compound I is currently in clinical trials for the treatment of auto-immune and auto-inflammatory diseases such as psoriasis.
US10899743B2 Substituted glycine derived FXIA inhibitors
The present invention provides compounds of Formula (I): (I) or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective factor XIa inhibitors or dual inhibitors of FXIa and plasma kallikrein. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating thromboembolic and/or inflammatory disorders using the same.
US10899738B2 Piperidines as menin inhibitors
The present disclosure provides compounds by Formula (I): (Formula (I)) and the pharmaceutically acceptable salts, hydrates, and solvates thereof, wherein R2, R3a, R3b, A, G, X, and Y are as defined as set forth in the specification. The present disclosure also provides compounds of Formula (I) for use to treat a condition or disorder responsive to menin inhibition such as cancer.
US10899737B2 Piperazine carbamates and methods of making and using same
Provided herein are piperazine carbamates and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful as modulators of MAGL and/or ABHD6. Furthermore, the subject compounds and compositions are useful for the treatment of pain.
US10899735B2 PD-1/PD-L1 inhibitors
Compounds and methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.
US10899727B2 Therapeutic aurones
Substituted aurones were found to have antitrypanosomal, antifungal and immunomodulatory activity. The invention provides novel aurone compounds, pharmaceutical compositions, and methods encompassing medical and veterinary applications.
US10899719B2 Aryl or heteroaryl triazolone derivatives or salts thereof, or pharmaceutical compositions comprising the same
The present technology provides aryl or heteroaryl triazolone derivatives or pharmaceutically acceptable salts thereof, preparation processes thereof, pharmaceutical compositions comprising the same, and the use thereof. The aryl or heteroaryl triazolone derivatives or their pharmaceutically acceptable salts exhibit selective inhibitory activity on VAP-1 and therefore can be usefully applied, e.g., for the treatment and prophylaxis of nonalcoholic hepatosteatosis (NASH).
US10899711B2 Quinolines, polyquinolines, molecular segments of fullerenes and graphene nanoribbons, and graphene nanoribbons and methods of their synthesis
Quinolines, polyquinolines, polybenzoquinolines, molecular segments of fullerenes and graphene nanoribbons, and graphene nanoribbons and processes for producing such materials are provided. The processes utilize a form of an aza-Diels-Alder (Povarov) reaction to first form quinolines and/or polyquinolines. In some such embodiments polyquinolines thus produced are used to form graphene nanoribbon precursors, and molecular segments and graphene nanoribbons. In many such embodiments the graphene nanoribbon precursors are formed from polybenzoquinolines.
US10899710B2 Pyridines and their use in the treatment of cancer
There is provided compounds of formula (I) or pharmaceutically-acceptable salts thereof, wherein L, R1, R2, R3, R4 and n have meanings provided in the description, which compounds are useful in the treatment of cancers.
US10899706B2 Method for preparing methionine
The present invention relates to a method for preparing methionine or methionine salts. In particular, the invention describes the step of preparing 2-hydroxy-4-(methylthio)butyronitrile (MMP-CN) from 3-methylthiopropanal (MMP) and hydrogen cyanide (HCN) in the presence of ammonia by bringing a gaseous mixture comprising HCN and ammonia into contact with MMP.
US10899701B2 Method for producing N-(alpha-alkoxyethyl)formamide
Provided are a method for producing N-(α-alkoxyethyl)formamide, comprising adding an acid catalyst to the mixed liquid within 3 hours from start of mixing after mixing of N-(α-hydroxyethyl)formamide with an alcohol has been started, by which the N-(α-alkoxyethyl)formamide can be produced at a high yield without additional investment in plant and equipment while suppressing an increase in the temperature of the mixed liquid and preventing corrosion of a pipe; and a method for producing N-(α-alkoxyethyl)formamide, comprising degassing carbon dioxide in the reaction of N-(α-hydroxyethyl)formamide with an alcohol, by which the N-(α-alkoxyethyl)formamide having a decreased carbonate concentration can be produced.
US10899699B2 Vinylogous phenethylamines as neurotransmitter releasers
The disclosure provides monoamine neurotransmitter releaser and/or monoamine uptake inhibitor compounds having biogenic amine transporter activity but lacking substantial activity at 5-HT2 receptor subtypes. The phenethylamine or vinylogous phenethylamine compounds of the disclosure are useful in treating diseases, conditions and/or disorders mediated by activity of one or more of the monoamine neurotransmitters.
US10899698B2 Bis(aryloxyalkyl) esters of aromatic polycarboxylic acids and method of preparation
The invention provides a compound of the formula: wherein Ar is selected from the group consisting of aryl, monosubstituted aryl and polysubstituted aryl, heteroaryl, monosubstituted heteroaryl and polysubstituted heteroaryl; Ar′ is selected from the group consisting of aryl, monosubstituted aryl and polysubstituted aryl, heteroaryl, monosubstituted heteroaryl and polysubstituted heteroaryl; R is an alkylene radical having 2-20 carbon atoms; and n=1-20. The compounds of the invention are used with polymer resins to enhance their gas barrier properties.
US10899689B2 Method for purifying 2-chloro-3,3,3-trifluoropropene and method for preparing 2,3,3,3-tetrafluoro-1-propene
The invention concerns a method for purifying 2-chloro-3,3,3-trifluoropropene (1233xf) from a first composition comprising 2-chloro-3,3,3-trifluoropropene and at least one of the compounds chosen from the group consisting of E-1-chloro-3,3,3-trifluoro-1-propene (1233zd E), 1,1,1,3,3-pentafluoropropane (245fa) and 1,1,1,3,3,3-hexafluoropropane (236fa), said method comprising the steps of bringing said first composition into contact with at least one organic extractant in order to form a second composition; extractive distillation of said second composition in order to form a third composition comprising at least one of the compounds chosen from the group consisting of E-1-chloro-3,3,3-trifluoro-1-propene (1233zd E), 1,1,1,3,3-pentafluoropropane (245fa) and 1,1,1,3,3,3-hexafluoropropane (236fa), and said organic extractant; and a stream comprising 2-chloro-3,3,3-trifluoropropene.
US10899688B2 Method for producing and purifying 2,3,3,3-tetrafluoro-1-propene
The invention relates to a method for producing and purifying 2,3,3,3-tetrafluoro-1-propene using a first composition comprising 2,3,3,3-tetrafluoro-1-propene, 3,3,3-trifluoropropene (1243zf), and trans-1,3,3,3-tetrafluoro-1-propene (1234ze-E), said method comprising the steps of: (a) bringing said first composition into contact with at least one organic extraction agent in order to form a second composition; (b) extractive distillation of said second composition in order to form (i) a third composition comprising said organic extraction agent, 3,3,3-trifluoropropene (1243zf), and trans-1,3,3,3-tetrafluoro-1-propene (1234ze-E), and (ii) a stream comprising the 2,3,3,3-tetrafluoro-1-propene; and (c) recovery and separation of said third composition in order to form a stream comprising said organic extraction agent and a stream comprising 3,3,3-trifluoropropene (1243zf) and trans-1,3,3,3-tetra-fluoro-1-propene (1234ze-E).
US10899680B2 High temperature initiator
According to an aspect, the present embodiments may be associated with a device and method of using an initiator including a body configured for receiving at least one explosive including barium 5-nitriminotetrazolate (BAX). According to a further aspect, the body of the initiator is configured for receiving at least two layers of explosive. In this embodiment, the layers of explosive include a primary explosive of the barium 5-nitriminotetrazolate (BAX) and a secondary explosive includes 2,6-Bis(picrylamino)-3,5-dinitropyridine (PYX) and/or Hexanitrostilbene (HNS).
US10899679B2 Forming evaporite mineral products and their use as fertiliser
A method for forming pellets of an evaporite mineral, the method comprising: exposing starch to water at greater than 70° C. so as to at least partially gel the starch; while the gelled starch is substantially fully hydrated, mixing the starch with a powder of the evaporite mineral to form a mixture; and pelletising the mixture.
US10899678B2 Method for processing a carbon-containing material to obtain a humus-containing product
The invention relates to agriculture, in particular to the processing of carbon-containing material to obtain a humus-containing product. A method for processing a carbon-containing material to obtain a humus-containing product by exposing it to a mixture of bacteria consisting of the strains Acinetobacter calcoaceticus VKPM (Russian National Collection of Industrial Microorganisms) V-4883, Pseudomonas denitrificans VKPM V-4884, Pseudomonas sp. “longa” VKPM V-4885 in an amount of (6-8)×109, (3-4)×109 and (2-3)×109 cells per 1 L of solution, respectively, in the presence of a phosphorus-containing additive, under aerobic conditions and while stirring, wherein the carbon-containing material is firstly ground to 0.5 mm in a wet mill while sapropel is simultaneously added in an amount of 5-10 wt %, and grinding is carried out for 30 minutes, the resulting mixture is sent into a mixer, into which aluminium industry waste in the form of dust from the cleaning of carbon electrodes with a particle size up to 0.5 mm in an amount of 10-20 wt % and a phosphorus-containing additive in an amount of 0.2-0.6 wt % are fed, mixing is carried out for 5-10 min, the resulting suspension is sent to a fermenter into which an inoculate has been fed beforehand in the form of a mixture of bacteria in an amount of 200-233 L per 1 m3 of suspension, and additionally stirring is performed while air is fed from 0.5 to 2.0 m3/min at a temperature of 15-20° C. for 28-30 h. The invention makes it possible to improve the quality of the target product.
US10899674B2 Composite fertiliser systems
A fertiliser pellet comprising: a first region of a nitrogen-providing fertiliser composition; and a second region adhered to the exterior of the first region, the second region comprising a fertiliser composition capable of providing (a) two or more alkali metal and/or alkaline earth metal nutrients and (b) sulphur.
US10899673B2 Method of protecting a composite material part against oxidation
A method of protecting a carbon-containing composite material part against oxidation, includes applying a first coating composition in the form of an aqueous suspension on an outside surface of the part, the first coating composition including a metallic phosphate; a powder of an ingredient comprising titanium; and a powder of B4C; subjecting the applied first coating composition to heat treatment in order to obtain a first coating on the outside surface of the part; applying a second coating composition on the first coating composition, the second coating composition including an aqueous suspension of colloidal silica; a powder of borosilicate glass; and a powder of TiB2; and subjecting the applied second coating composition to second heat treatment in order to obtain a second coating on the first coating.
US10899669B2 Boron aluminum silicate mineral material, low temperature co-fired ceramic composite material, low temperature co-fired ceramic, composite substrate and preparation methods thereof
The present invention relates to a boroaluminosilicate mineral material, a low temperature co-fired ceramic composite material, a low temperature co-fired ceramic, a composite substrate and preparation methods thereof. A boroaluminosilicate mineral material for a low temperature co-fired ceramic, the boroaluminosilicate mineral material comprises the following components expressed in mass percentages of the following oxides: 0.41%-1.15% of Na2O, 14.15%-23.67% of K2O, 1.17%-4.10% of CaO, 0-2.56% of Al2O3, 13.19%-20.00% of B2O3, and 53.47%-67.17% of SiO2. The aforementioned boroaluminosilicate mineral material is chemically stable; a low temperature co-fired ceramic prepared from it not only has excellent dielectric properties, but also has a low sintering temperature, a low thermal expansion coefficient, and high insulation resistance; it is also well-matched with the LTCC process and can be widely used in the field of LTCC package substrates.
US10899667B2 Covalently cross-linked lignocellulosic composites and applications thereof
In one aspect, composite polymeric composition and related materials are described herein employing waste products from the agricultural and energy industries. Such composite polymeric compositions and materials can repurpose agricultural and petroleum waste products for various applications including, but not limited to, building and/or infrastructure materials. In some embodiments, a composite polymeric composition described herein comprises polysaccharides, lignin or combinations thereof covalently cross-linked via linkages comprising sulfur.
US10899665B2 Hydrophobic construction material
A construction material, a hydrophobic, optionally multi-cellular, inorganic particulate material for use in the construction material, for example, to improve the crush strength and/or stability of the construction material, a method of making the construction material, constructions comprising the construction material, and a method of improving the stability of a construction material.
US10899663B2 Process for producing modified fly ash
A process for producing a modified fly ash comprising the steps of providing, as a raw material, the raw fly ash discharged from a pulverized coal combustion boiler; classifying the raw fly ash into a crude powder and a fine powder; removing the unburned carbon contained in the crude powder by heating the crude powder at a temperature in a range of 500 to 1000° C.; and mixing together the crude powder from which the unburned carbon has been removed and the fine powder to obtain a modified fly ash.
US10899658B2 Crystallized glass and crystallized glass substrate
Provided is a high-strength crystallized glass or substrate having a high visible light transmittance and a good color balance, which is suitable for use in protecting members of portable electronic devices, optical devices and the like. Provided is a crystallized glass comprising, in terms of mol % on an oxide basis: an SiO2 component of 30.0% or more and 70.0% or less, an Al2O3 component of 8.0% or more and 25.0%, an Na2O component of 0% or more and 25.0% or less, an MgO component of 0% or more and 25.0% or less, a ZnO component of 0% or more and 30.0% or less and a TiO2 component of 0% or more and 10.0% or less, the molar ratio [Al2O3/(MgO+ZnO)] having a value of 0.5 or more and 2.0 or less, and comprising one or more selected from RAl2O4, RTi2O5, R2TiO4, R2SiO4, RAl2Si2O8 and R2Al4Si5O18 as a crystal phase.
US10899656B2 Glass composition, preparation method of glass composition, and cooking appliance
A glass composition formed of glass frit including P2O5, TiO2 and group I-based oxide, wherein P2O5 is contained in an amount of 20 wt % to 30 wt % based on a total weight of the glass frit, wherein TiO2 is contained in an amount of 10 wt % to 20 wt % based on the total weight of the glass frit, and wherein the group I-based oxide is contained in an amount of 15 wt % to 30 wt % based on the total weight of the glass frit.
US10899650B2 Methods and apparatus for processing glass
Disclosed is an apparatus and method of making molten glass. The apparatus includes a glass former having a slot orifice design to deliver a glass ribbon. The slot orifice design can include a transition section, a slot extension, and external structural reinforcements. In some embodiments, the orifice opening distance of the slot extension varies along the width of the orifice. In some embodiments, the orifice has an orifice opening distance that is smaller at the center of the slot extension than at the edges of the slot extension, which limits glass flow at the center of the slot extension. Also disclosed is a method of making glass using the disclosed apparatus.
US10899649B2 System and method for cooling moulds for a machine used to form hollow glass items
The present invention relates to mold cooling method and system for a glass container forming machine that includes at least one mold holder including mold halves that are movable between a closed mold position for forming the glass article and an open mold position for releasing said article, each of the mold halves having axial passages for cooling each of the mold halves. A support structure having a fixed upper support section and a movable support section. Means for providing a cooling flow are coupled in coincidence with a series of openings in the movable support section. A cooling flow distributor located above the movable support section, the cooling flow distributor having a lower section in coincidence with each of the openings of the movable support section for the passage of the cooling flow and, a upper section in coincidence with each of the axial passages of each of the halves of each mold, the cooling flow distributor being movable between the closed mold position and the open mold position.
US10899648B2 Ion-conducting glass ceramic having garnet-like crystal structure
A glass ceramic containing lithium-ions and having a garnet-like main crystal phase having an amorphous proportion of at least 5% is disclosed. The garnet-like main crystal phase preferably has the chemical formula Li7+x−yMxIIM3−xIIIM2−yIVMyVO12, wherein MII is a bivalent cation, MIII is a trivalent cation, MIV is a tetravalent cation, MV is a pentavalent cation. The glass ceramic is prepared by a melting technology preferably within a Skull crucible and has an ion conductivity of at least 5·10−5 S/cm, preferably of at least 1·10−4 S/cm.
US10899641B2 Degassing device for anaerobic purification device
A gas-liquid separation device (30) for an anaerobic purification device for purification of wastewater, the gas-liquid separation device comprising: a gas-liquid riser pipe (32); a separation pipe (34) attached to the gas-liquid riser pipe (32), the separation pipe defining an angle with the direction perpendicular to the gas-liquid riser pipe between −45 degrees and +45 degrees, the separation pipe (34) configured to receive fluid from the gas-liquid riser pipe (32); at least one pipe gas outlet (35) located, when assembled with an anaerobic purification device, in a surface along the separation pipe (34) facing away from the ground, the at least one pipe gas outlet (35) configured to lead at least a portion of the gas in the separation pipe (34) outside the gas-liquid separation device; a hydraulic cyclone (36) attached to the separation pipe (34), the hydraulic cyclone configured to receive fluid from the separation pipe; at least one cyclone gas outlet (37) located in the upper side of the hydraulic cyclone (36); the at least one cyclone gas outlet configured to lead the gas entering the hydraulic cyclone (36) outside the hydraulic cyclone; and a liquid outlet (38) attached to the bottom part of the hydraulic cyclone (36), the liquid outlet configured to guide degassed fluid outside the hydraulic cyclone.
US10899640B1 Anaerobic waste digestion system
Methane is generated from animal waste by anaerobic digestion using bacteria. A screen separator removes suspended solids greater in size than a predetermined size ranging from about 50μ to about 150μ. An electrocoagulation unit electrochemically hydrolyses the waste, causing particles to settle out. A dissolved carbon air flotation has a CO2 bubbler for separating large particles from small particles by flotation. An anaerobic digester produces biogas. The digester has a biocurtain for growing the bacteria and a heat exchanger for heating the bacteria. The biocurtain surface is convoluted to retain the bacteria. A membrane module removes CO2. A knock out pot for removes droplets of water. A scrubber removes water vapor, particulates, and contaminant gas. A compressor boosts pressure. A gas chromatograph monitors the biogas composition. A flare skid lowers excess pressure for safety. Biogas is injected into a local pipeline system. A process control is used for controlling the anaerobic waste digestion system.
US10899639B2 Composition and method for inhibiting microbial adhesion on surfaces
A composition includes a surfactant that is a linear alkylbenzene sulfonate, an acid thereof, or a combination thereof and that is present in an amount of from about 5 to about 30 weight percent actives based on a total weight of the composition and has the structure: wherein each m is independently a number of from 0 to 16, each n is independently a number of from 0 to 16, the sum of each m+n is a number of from 4 to 16, and X is a counter ion. The composition also includes a defoamer in an amount of from about 1 to about 20 weight percent actives based on a total weight of the composition, a thickening agent in an amount of from greater than zero to an amount of about 3 weight percent actives based on a total weight of the composition, and water.
US10899636B2 Magnetization and manipulation of hydrophobic absorbents
The present invention includes a method of controlling an oil spill through introduction of a plurality of magnetizable particles into the oil spill in an amount sufficient to form a colloidal mixture. An absorbent is, also introduced into the oil spill to form an absorbent mixture. A magnetic field can be applied to the system to move, manipulate, or otherwise control the absorbent mixture in response to movement of the magnetic field.
US10899635B2 Seawater desalination device of industrial exhaust heat-driven ejector refrigeration and application method thereof
A seawater desalination device of industrial exhaust heat-driven ejector refrigeration and an application method thereof. The seawater desalination device comprises a seawater collecting pool, a low-pressure seawater storage tank, an ejector refrigeration system and a fresh water storage tank which are fluidly connected; the ejector refrigeration system comprising a nozzle for spraying low-pressure vapor, a mixing chamber, a diffuser, a first heat-exchanger, a condenser, a condensate pump and a generator; bottom of the low-pressure seawater storage tank being connected with a second heat-exchanger; the mixing chamber being connected with the nozzle, the diffuser and the low-pressure seawater storage tank, respectively; and the diffuser, the first heat-exchanger, the condenser and the fresh water storage tank being successively connected.
US10899633B1 Modular porous swale filtration system
A modular porous swale filtration system. The modular porous swale filtration system may comprise one or more modular porous swales, absorption media, liner, and perforated pipe. Each modular porous swale may have a porous concrete block and filtration joint. The porous concrete block may snugly fit within a trench having a lower portion filled with the absorption media. The absorption media may include gravel, activated alumina, bone char, or an activated alumina and bone char mixture. The porous concrete block may have a top surface inwardly-sloped to a nadir. The filtration joint may be disposed within the porous concrete block and along the nadir. The liner may cover one or more surfaces of the trench. The perforated pipe may be located within the absorption media. The filtration joint may substantially align above a portion of the perforated pipe when the modular porous swales are installed within the trench.
US10899629B2 Method for producing stannous sulfide
A method for producing stannous sulfide, the method including: 1) heating a tin-containing material to 200-600° C., and mixing sulfur with the tin-containing material heated, to yield a product; and 2) distilling the product in a vacuum furnace at a pressure of 1-500 pascal.
US10899622B2 Biobased carbon fibers and carbon black and methods of making the same
Bio-based materials, e.g., epoxide starting material, a beta-lactone starting material and/or a beta-hydroxy amide starting material, may be used as feedstocks in processes for making and using acrylonitrile and acrylonitrile derivatives to produce, among other products, carbon fibers and carbon black.
US10899621B2 System and method for preparing graphene oxide and reduced graphene oxide
There is provided an industrially scalable system and method for preparing graphene oxide and thereafter reduced graphene oxide, with high yields (generally better than 98 percent), in which the yield and quality are maximized. In certain embodiments of the present method and process, the initial particle size of the graphite charge and the temperature profile are of greater importance to a successful outcome than the reactants themselves. It should be noted that unlike the previous Hummers methods and derivatives, secondary oxidizers and exfoliation agents such as nitric acid, sodium nitrate and similar intercalation agents are not necessary to achieve the desired result.
US10899619B2 Method for producing carbon nanotube web, method for producing carbon nanotube collected product, and apparatus for producing carbon nanotube web
The method for producing a carbon nanotube web includes preparing a carbon nanotube array disposed on a substrate, the carbon nanotube array including a plurality of carbon nanotubes vertically aligned relative to the substrate; and drawing a carbon nanotube web from the carbon nanotube array so that the plurality of carbon nanotube single yarns are arranged in parallel, wherein in the step of drawing a carbon nanotube web, the carbon nanotube web is oscillated in a direction crossing both the thickness direction of the substrate and the drawing direction of the carbon nanotube web.
US10899618B2 Aqueous solution containing aluminum ions, lactate ions, and phosphate ions, and a method for their production
The invention relates to an aqueous solution containing aluminum ions, characterized in that the solution contains aluminum ions in a proportion of 0.5-15% (converted, if necessary, to Al3+) based on the total mass of the solution, as well as anions of lactic acid (lactate ions) and of phosphoric acid (phosphate ions), and has the theoretical composition Al3+A(C3H5O3−)x.ASM−y.A(H2PO4−)z.A(OH)−(3A-x.A-M.y.A-z.A), wherein S is the anion of an acid with the charge M, x is a value in the range of 0.5-2.8, y is a value in the range of 0-1.5, and z is a value in the range of 0.01-1.5.
US10899617B2 Method for removing N2O and NOx from the nitric acid production process, and an installation suitable for same
An apparatus is provided for treatment of process gas formed during nitric acid production by catalytic oxidation of NH3. The apparatus includes a reactor, a first catalyst bed for N2O decomposition, an absorption tower to react the NOx formed with an absorption medium downstream of the first catalyst bed, a device for adding NH3 added to tailgas entering the second catalyst bed, and a second catalyst bed for NOx reduction and further decrease in N2O in the tailgas exiting the absorption tower. The second catalyst bed contains at least one iron-loaded zeolite catalyst. N2O removal in the first catalyst bed is limited such that the process gas exiting the first catalyst bed exhibits a N2O content of >100 ppmv and a molar N2O/NOx ratio of >0.25. Treated gas exiting the second catalyst bed has a NOx concentration of <40 ppmv and a N2O concentration of <200 ppmv.
US10899613B2 Graphene-ceramic composite membrane for hydrogen separation membranes
A hydrogen permeation membrane is provided that can include a carbon-based material (C) and a ceramic material (BZCYT) mixed together. The carbon-based material can include graphene, graphite, carbon nanotubes, or a combination thereof. The ceramic material can have the formula BaZr1-x-y-zCexYyTzO3-δ, where 0≤x≤0.5, 0≤y≤0.5, 0≤z≤0.5, (x+y+z)>0; 0≤δ≤0.5, and T is Yb, Sc, Ti, Nb, Ta, Mo, Mn, Fe, Co, Ni, Cu, Zn, Ga, In, or a combination thereof. In addition, the BZYCT can be present in the C-BZCYT mixture in an amount ranging from about 40% by volume to about 80% by volume. Further, a method of forming such a membrane is also provided. A method is also provided for extracting hydrogen from a feed stream.
US10899612B2 Hydrogen production reactor including carbon monoxide removing unit
Provided is a hydrogen production reactor as a reactor producing a reforming gas including hydrogen, in which a burning unit and a reforming unit are sequentially arranged and spaced apart from each other in a concentric structure based on a raw material transfer pipe positioned at a central axis of the reactor, including a heating raw material transfer pipe supplying a raw material to the burning unit, a burning unit burning the supplied raw material and supplying heat to the reforming unit, a reforming raw material phase change pipe positioned within the burning unit and heating the supplied raw material, and a reforming unit reforming the phase-changed raw material supplied from the reforming raw material phase change pipe, wherein the reforming raw material phase change pipe is provided as a coil surrounding an outer circumferential surface of a lower end of the heating raw material transfer pipe.
US10899611B1 Method of producing hydrogen through laser ablation
The process describes the capability of solid-state metals to oxidize in water to produce hydrogen when stimulated by laser. The solid-state metals with an adherent surface layer of the oxide component is introduced into water or another suitable oxidizer. The metal-oxidizer reaction to form hydrogen is initiated and maintained by a laser periodically/continually ablating the metal. The energy, pulse duration and wavelength of the laser may be tailored to control the rate of reaction of the source material with the oxidizer, and thereby control the rate of formation of hydrogen. Application of energy produced by such method may include powering large scale commercial and residential energy companies, providing sustainable and continuous fuel for intergalactic missions, providing an alternative fuel sources for on-board hydrogen-powered vehicles and smaller scale applications such as emergency generators.
US10899609B1 Microscale metallic CNT templated devices and related methods
A method for forming a microscale device may include growing, by a chemical vapor deposition, a patterned forest of vertically aligned carbon nanotubes, wherein the patterned forest defines a component of the microscale device, and applying a conformal non-metal coating to the vertically aligned carbon nanotubes throughout the patterned forest, wherein the conformal non-metal coating comprises a substantially uniform thickness along a length of the vertically aligned carbon nanotubes. The method may also include connecting adjacent vertically aligned carbon nanotubes together with the conformal non-metal coating without filling interstices between the adjacent vertically aligned carbon nanotubes, wherein the connecting of the vertically aligned carbon nanotubes is configured to increase a strength of the vertically aligned carbon nanotubes of the patterned forest above a threshold level to withstand forces applied during a wet etching process, and infiltrating the interstices between the adjacent vertically aligned carbon nanotubes with a metallic material.
US10899606B2 Microneedles
A method is for manufacturing a plurality of silicon microneedles which have a bevelled tip. The method includes providing a silicon substrate having a front face and a rear face, forming a first mask arrangement on the front face of the substrate, the first mask arrangement defining one or more gaps, and performing a SF6 based plasma etch of the front face through the gaps in the first mask arrangement to provide one or more etch features having a sloping face. The SF6 based plasma etch undercuts the first mask arrangement with an undercut that is at least 10% of the depth of a corresponding etch feature. The method further includes forming a second mask arrangement on the etch features to define locations of the microneedles, in which the second mask arrangement is located entirely on sloping faces of the etch features, and performing a DRIE (deep reactive ion etch) anisotropic plasma etch of the etched front face of the substrate to form a plurality of microneedles which have a bevelled tip, where the sloping faces of the etch features at least in part give rise to the bevelled tips of the microneedles.
US10899605B2 MEMS device and manipulation method for micro-objects
A micro-electro-mechanical systems (MEMS) includes a flexible membrane that creates a suction force by flexing to permit manipulation of a microscale object. The MEMS element includes a casing structure; a flexible membrane attached to the casing structure; and an electrode structure, wherein a voltage applied to the electrode structure causes the flexible membrane to flex relative to the casing structure. The flexible membrane and the casing structure define a gap into which the flexible membrane may flex, and a foot extending from the flexible membrane in a direction away from the casing structure, wherein the foot and the flexible membrane define a clearance region on an opposite side of the flexible membrane from the gap. When the MEMS element interacts with an object to be manipulated the foot spaces the membrane apart from the object, and flexing of the membrane generates the suction force for manipulating the object.
US10899595B2 System and method for tracking dispensed products at participating customer locations
A system and method a method may include receiving (i) beverage composition data of a requested beverage, and (ii) a user identifier of a user requesting the beverage. Responsive to receiving an instruction to dispense the requested beverage, the requested beverage may be dispensed. The beverage composition data may be stored in a dispensed beverage data record. A verification as to whether or not the dispensed beverage is a qualified beverage pour may be performed. Responsive to determining that the dispensed beverage is a qualified beverage pour, a counter may be increased. Responsive to determining that the counter value crosses a threshold value, a first message may be communicated to a mobile electronic device of the user, otherwise, a second message may be communicated to the mobile electronic device. The first or second message may be displayed on the mobile electronic device.
US10899590B2 Winch for a vehicle having damage protection
A winch and method for operating the winch includes a winch body having a first drum support, a second drum support and a drum rotatably coupled to the first drum support and the second drum support. The winch further comprises a plurality of gears coupled to the second drum support and the drum. A motor is coupled to the drum through the plurality of gears. A motor cover is coupled to the first drum support. A gear cover is coupled to the second drum support and houses the plurality of gears therein. A supplemental cover covers at least a portion of the motor cover or a portion of the gear cover or both.
US10899583B2 Rope storage unit and a method for installing an elevator rope
A rope storage unit for storing an elevator rope during transportation and/or installation of the elevator rope includes a rope reel, formed by a rope wound in a spiral form and having a central axis; and a support frame provided with an inner space inside which the rope reel is positioned supported by the support frame such that it can in use be rotated in the inner space for unwinding the rope. The rope is a rod having a straight form when in rest state and elastically bendable away from the straight form, the rope being under substantial bending tension in the spiral form, and wherein the support frame comprises three or more rotatable support rollers delimiting the inner space and surrounding radially the rope reel. A method for installing an elevator rope implements the rope storage unit.
US10899579B2 Elevator brake controller
The invention refers to an elevator brake controller, comprising a brake supply circuit comprising a rectifier with a mains input side and a DC link output side, whereby in the mains input side and/or in the DC link output side at least one fuse is connected, a brake control circuit with at least one brake coil of an elevator brake, which brake coil is connected in series with a control switch configured to be controlled by an elevator control, which series connection of brake coil and control switch is connected to the DC link, a brake safety circuit which is connected between the brake supply circuit and the brake control circuit, which brake safety circuit comprises a first safety switch being connected in series with the brake coil as well as a second safety switch which is connected in parallel to the brake coil, whereby the first and second safety switches are configured to be controlled by an elevator safety circuit. This brake controller offers an improved cut-off safety in safety relevant situations.
US10899578B2 Arrangement and method for detecting at least one operational parameter of an automatic door
The invention relates to an arrangement for detecting operational information of an automatic door. The arrangement comprises a magnetometer arranged to at least one of the following: moving part of the door, structure that is separate from the moving part of the door. The arrangement further comprises at least one permanent magnet arranged to the other one of the following: moving part of the door, structure that is separate from the moving part of the door. The magnetometer is configured to detect data representing the magnetic field generated by the at least one permanent magnet during a predefined time. The arrangement further comprises a control unit configured to define the operational information of the door from the detected data. The invention also relates to a method for detecting operational information of an automatic door.
US10899577B2 Automatic winding device
An automatic winding device includes a lower casing having a shaft, a bobbin rotatably disposed on the shaft, a wire wound around the bobbin, a spring having a first end secured to the shaft and a second end secured to the bobbin to provide a rotational force to the bobbin, a track cover coupled to the bobbin and having tracks formed thereon, a pin positioned between the bobbin and the track cover to control rotation of the bobbin, and a pin guide spring configured to press the pin toward the track cover. The track cover includes an inner track having a radius of curvature increased and decreased along the circumferential direction, an outer track spaced apart from the inner track, a connection track configured to connect the inner and outer tracks, and a stop track configured to connect the inner and outer tracks and to stop the pin.
US10899576B2 Cord reel apparatus
A cord reel apparatus includes a circular plate configured to rotate in response to pulling out or rewinding of a cord, a guide groove on the circular plate, a sensor member having a first protrusion which is slidable in the guide groove, a top plate facing the circular plate with the sensor member sandwiched therebetween, a second protrusion provided on the sensor member and projecting in a direction toward the circular plate, and a first pressing portion provided on the sensor member and disposed in a direction toward the top plate. When the first protrusion is closest to a bottom surface of the guide groove, the second protrusion is not in contact with the circular plate. When the first protrusion rides on a wall surface of the guide groove, the first pressing portion is in contact with the top plate, so that the second protrusion contacts the circular plate.
US10899569B2 Apparatus for conveying molded body for flattened tube fins
A conveying apparatus can achieve high-speed conveyance of a molded body for flattened tube fins, prevent generation of noise during conveyance, and have a smaller size. A conveying apparatus conveys a molded body for flattened tube fins obtained by providing a metal thin plate with cutaway portions, before the metal thin plate is cut into a predetermined length. The conveying apparatus includes a rotary conveying body including a plurality of protrusions that are tapered and able to enter the cutaway portions, and including a rotation shaft in a direction orthogonal to a conveying direction of the molded body for flattened tube fins in a horizontal plane, and a rotary conveying body driving unit that rotates and drives the rotary conveying body. A side surface shape of each of the protrusions is formed to have a shape to enable the protrusion to enter the corresponding cutaway portion with a space maintained in synchronization with a rotation of the rotation shaft, and retract from the cutaway portion while the protrusion comes in contact with the cutaway portion and conveys the molded body for flattened tube fins.
US10899563B1 Self-clearing counter-stacker with stacking frame
Methods, systems, and apparatus, including computer programs encoded on computer storage media, for removing a non-conforming comestible from a counter-stacker. One of the methods includes receiving, on an upper conveyor included in a counter-stacker, a first comestible; transferring, by the counter-stacker that includes a stacking frame and a stacking platform and while the first comestible substantially maintains its shape, the first comestible through an aperture defined within the stacking frame and onto the stacking platform; creating, by the counter-stacker, a stack of comestibles that includes the first comestible and has a threshold quantity; receiving, on the upper conveyor, a second comestible; rotating, by one or more actuators included in the counter-stacker that are coupled to the stacking frame, the stacking frame to cause the second comestible to fall onto a lower conveyor; and removing, by the lower conveyor, the second comestible from the counter-stacker.
US10899562B2 Apparatus for transferring and/or stacking products
An apparatus for transferring and/or stacking products, the apparatus including a frame, a bar conveyor associated with the frame, the bar conveyor having a plurality of flight bars that are independently driven by a plurality of independent drivetrains, a lifting device having a lifting plate, the lifting device being located within the bar conveyor, and at least one pusher.
US10899560B2 Robotic system for picking, sorting, and placing a plurality of random and novel objects
The present disclosure generally relates to pick and place robotic systems. An exemplary apparatus for vacuum-gripping a deformable bag comprises: a primary chamber, wherein a proximal end of the primary chamber is connected to an air flow source, and wherein the primary chamber is configured to, upon an activation of the air flow source, receive a portion of the deformable bag via a distal end of the primary chamber; a secondary chamber surrounding the primary chamber, wherein the secondary chamber is connected to the primary chamber via a plurality of connections to allow for air passage, and wherein the activation of the air flow source causes a lateral wall of the primary chamber to grip the portion of the deformable bag via pressure differential between an inside of the deformable bag and the secondary chamber.
US10899557B2 Product transfer
Disclosed is a device for transferring products, which includes a delivery unit for delivering said products, which moves them one behind the other in a feed direction, and, on the other hand, an output conveyor, extending from the delivery unit, transversely to the delivery direction. This device further includes a rotary tool that rotates about a rotation axis, this tool having collectors distributed radially about the axis and being movable parallel to the delivery direction, such that the rotation of the tool causes each successive collector to release a group of products from the delivery means to the outlet conveyor. Also disclosed is a corresponding method.
US10899556B2 Device and method for transporting meat products
A slaughtered animal meat handling device and a method for transporting meat products from a receiving area to a discharge area device are provided. The device includes at least one supply conveyor, a suction transporter and at least one return conveyor. Meat products that are not engaged by the suction transporter are transported away from the transfer area towards the receiving area by the return conveyor. The meat products are reintroduced onto the supply conveyor away for the transfer area, for again being transported towards the transfer area. The supply conveyor and the return conveyor provide a circulation of meat products. By reintroducing the meat products onto the supply conveyor away from the transfer area, the chance of getting the meat products correctly positioned on the supply conveyor with respect to a suction opening of the suction transporter is increased.
US10899554B2 Device and method for transporting containers
An apparatus for transporting containers along a transport route includes first and second transport elements, at least one of which comprises grippers that are radially movable in relation to a vertical machine axis about which said first transport element rotates. The said first and second transport elements define a transport route that comprises first and second transport-route sections defined by circular arcs and a third transport-route section disposed between them. The third transport-route section comprises a transport-route region that defines a course having a kink-free transition-curve section having a curvature that either only increases or only decreases.
US10899553B2 Moveable article restriction device
Systems, methods, and apparatus are provided for restricting access to articles on a conveyor. The apparatus includes a locking mechanism configured to move via a plurality of actuators, wherein at least two of the actuators move the locking mechanism in differing directions, and also configured to prevent removal of at least one article from the conveyor while in a locking position against the conveyor, wherein at least one of the actuators is configured to move the locking mechanism into the locking position.
US10899551B1 Angle adjustment mechanism for a conveyor bed
A conveyor bed is provided that can include a conveyor frame, a roller frame and an adjustment mechanism. The adjustment mechanism can include a first wheel movable on a first rail and a second wheel movable on a second rail. A sled can be coupled to a bottom face of the roller frame, where an inner face of the sled is in contact with the first wheel and the first rail and an outer face of the sled is in contact with the second wheel and the second rail. An actuable component coupled to the sled, wherein the actuable component is configured to move the sled back and forth linearly along the first rail using the first wheel in response to rotation of the actuable component, wherein a movement of the sled rotates the second wheel and pivots the second rail to alter an angle of the roller frame.
US10899550B2 Positive drive conveyor
The invention relates to a positive drive spiral conveyor which includes, a drive tower rotatable about a vertical axis and a plurality of drive members extending in length from a bottom to a top of the drive tower. The drive members are spaced radially around the drive tower, with each drive member having a projecting driving ridge extending in length along at least a section of each drive member with a projecting shaft positioned on each drive member proximate an end of the driving ridge thereby defining an engagement zone. The projecting shaft defines a guiding surface around the shaft, such that in use a positive drive protrusion of a conveyor belt engages the guiding surface of the projecting shaft and is guided towards a leading side of the driving ridge.
US10899548B2 Telescopic conveyor
The present invention provides a telescopic conveyor (1) having at least two conveyor belts (10). Said belts are arranged one above the other and can be moved relative to one another in the longitudinal direction. Each conveyor belt (10) here has a frame (11), a circulatory belt (12) and a first deflecting roller (13) at a first end (A), and a second deflecting roller (14) at a second end (B), of the conveyor belt (10), wherein the second end (B) is a transfer end of the conveyor belt (10), and wherein a bridging device (2′, 2) is provided between in each case two adjacent conveyor belts (10) located one above the other, and said device bridges, at least to some extent, the difference in height (H) between the two conveyor belts (10) arranged one above the other, it being necessary for said difference in height to be overcome at the transfer end. The bridging device (2) comprises a ramp (3, 3′) with a slope (S) and also a first deflecting roller (4), which is arranged at the higher end of the ramp (3, 3′), as well as a first holding-down device (5), which is arranged beneath the first deflecting roller (4), and also a second holding-down device (7) at the foot of the ramp (3, 3′). The circulatory belt (12) of the respectively lower conveyor belt (10) is guided, from a conveying plane (E1) beneath the second holding-down device (7), over the ramp (3, 3′) with the slope (S) and, from there, is deflected over the first deflecting roller (4) and guided back to the conveying plane (E1) beneath the first holding-down device (5). The slope (S) of the ramp (3, 3′) continues in stepless fashion tangentially along the circulatory belt (12) of the conveyor belt (10) located above, said circulatory belt being guided over its second end-side deflecting roller (14).
US10899547B1 Coupling block on a conveyor system
A coupling block is provided to dynamically adjust a difference in height between a first support structure and a second support structure attached to a conveyor frame. The coupling block includes at least one rotating cam attached to the coupling block. The rotating cam is actuated to move at least a portion of the coupling block about an axis to compensate for a height difference between the first support structure and the second support structure. A cam adjuster is also accessible from an outer face of the of the conveyor frame to change a direction of rotation of the at least one rotating cam.
US10899543B2 System for collection of products
According to a first aspect of the invention, there is provided a system for collection of products, the system comprising: at least one carrier (8) for carrying products (40); a collection point (14), at which collection point a user (10) of the system can remove products from the carrier; and a transporter arrangement (16, 20) for transporting the carrier to the collection point; wherein the system is arranged to physically inhibit (42) removal of the carrier by the user from the collection point.
US10899535B2 Pack for cigarettes and method and apparatus for producing said pack
A pack for cigarettes having an outer pack and an inner pack with a blank that surrounds a cigarette group, the inner pack having a removal opening for accessing the pack contents, and the inner pack having a closure flap fastened to it by a releasable adhesive bond and being removable for access to the removal opening or pack contents. For forming the removal opening, the blank has an opening that is closable by the closure means, the closure means having a coverage region that, with the closure means in the closed position, circumferentially surrounds the opening and is adhesively connectable to a region of the blank that surrounds the opening, and a separate blank is adhesively fastened on the closure means on the side facing the inner pack, the separate blank, with the closure means in the closed position, covering the opening and overlapping the opening on all sides.
US10899532B2 Insulated container
A container is formed to include and interior region that is configured to receive a product therein and the container is insulated.
US10899522B2 Closure for container
A package includes a container and a closure. The container includes a body formed to include a product-storage region adapted to store products therein and a brim coupled to the body and formed to include a mouth opening into the product-storage region. The closure is coupled to the brim of the container by melting a portion of the closure together with a portion of the brim to block access to the products stored in the product-storage region.
US10899518B2 Water-soluble packets
The disclosure provides a water soluble pouch including at least two sealed compartments, the pouch including outer walls including water soluble film including a water soluble resin, and an inner wall including water soluble film including a water soluble resin, the outer wall films being sealed to the inner wall film, the outer wall films being characterized by: a dissolution time of 300 seconds or less, the water soluble resin of the outer wall films having a viscosity in a range of 14.5 cP to 25 cP, and a pouch strength of at least 200 N, and the inner wall film being characterized by: a dissolution time of 300 seconds or less, the water soluble resin of the inner film having viscosity in a range of 12 cP to 14.5 cP, and a tackiness value of at least 1500 g/s.
US10899512B2 Food jar
A food jar is described that may be used to store and transport food items. The food jar includes a container, a lid, and a vent. As the lid is unscrewed from the container, the vent opens to equilibrate air pressure within the container with the atmosphere. The vent relieves high and low pressure within the container. The food jar may also include stopper with a vent. The stopper may include an upper and a lower stopper that form the vent.
US10899508B1 Overmolded tricuspid valve for a container
An overmolded tricuspid valve for use in a container having a throat. The valve is inserted into the throat of the container and permits liquid from flowing from the container during shipment or storage. The container is inverted when used with a dosing and/or dispensing apparatus. The valve remains closed until it is opened by an upward force to permit liquid to flow from the container to the dosing and/or dispensing apparatus. The valve closes when the upward force is removed.
US10899507B2 Cap and container for Carbonated drinks
A cap and container reduce carbonation loss in filling containers with carbonated beverages. The cap has a splashguard with a circular bottom connected by a conical transition to a smaller diameter, cylindrical ring portion. A circular dispersing disk is above the transition and connected to the cap, with a small radial gap between the disk's periphery and the splashguard. A fluid seal is interposed between the ring portion and an open top of the container. The dispersing disk directs a fluid stream outward against the splashguard where the fluid passes through the radial gap around the disk and flows downward in a laminar flow over the conical transition and ring portions. A lip on the bottom of the ring portion extends outward and downward to conduct the laminar flow onto the container sidewall, which is inclined at less than five degrees to maintain laminar flow along the sidewall when filling.
US10899503B2 Spigot and spigot guard for an insulating container
An insulating container having a base and a lid is provided. The lid may be rotatable about a hinge from a closed configuration to an open configuration and may be secured, via one or more latching devices, in either the closed configuration or the open configuration. In some examples, the rotatable lid may be non-destructively removable from the base. Some example arrangements include a removable lid that, when removed, may be secured to the base via an additional portion of the latching device. Additional features of the insulating container include handles that are integrally formed with the base, a recess formed in the base and housing a spigot, and/or a spigot guard, and/or an insulating container mount.
US10899492B2 Reusable cup with integrated ribbed heat sink sheath
Aspects of the disclosure relate to a cup including a base, a sidewall extending upward from the base to a top of the cup to define an internal cavity and an open top, wherein the sidewall includes an upper sidewall and a lower sidewall located between the upper sidewall and the base. The lower sidewall can include a lower wall and a plurality of raised ribs extending radially outward from the lower wall and being separated by recesses and the ribs and recesses being elongated in a direction between the top and the base. The cup can include an annular ledge connects the upper sidewall to the lower sidewall, wherein the annular ledge extends inwardly from the upper sidewall to the lower sidewall and forms a reduction in width of the sidewall between the upper sidewall and the lower sidewall.
US10899491B2 Equipment and corresponding method for managing commercial items
Equipment (100) for processing items intended for commercial and non-commercial distribution, said equipment comprising a conveyor belt (1) for transporting and/or moving said items, means (30) for applying individually a label onto each of said items, said equipment (100) being configured so that each label is generated by means (34) for generating individual labels based on the identification data of the associated or corresponding item.
US10899488B2 Bale opening device
A bale opening device for opening bales wrapped and/or tied with wrapping material comprises a supporting structure for supporting the bale to be opened, and a gripping mechanism to grip the wrapping material, and again to pull it away from the bale. In addition, the device comprises a remover taking and gripping the wrapping material from the gripping mechanism. The remover is then actuated so as to remove the wrapping material from the bale and the gripping mechanism. The remover and the gripper are mutually arranged so to enable the gripping mechanism returning back towards the supporting structure essentially at the same when the remover is actuated to remove the wrapping material.
US10899486B2 Packaging machine with stackable protective covers
A packaging machine comprising a sealing station with a sealing tool, a side frame and at least a first as well as a second upper protective cover respectively for placement onto a top side of the side frame during the manufacturing operations, wherein each of the two protective covers form a body with a lid, multiple side walls as well as a bottom. In one embodiment, the two protective covers can be stacked on one another, wherein at least one of the two protective covers forms at least one stack stop on the lid to which an edge of the floor of the other protective cover can be coupled in a removable way if the two protective covers are stacked on top of one another. In one embodiment, the packaging machine may be a deep-drawing packaging machine or a tray-sealing machine.
US10899483B2 Paper sheet handling apparatus and paper sheet handling method
A paper sheet handling apparatus (for example, a banknote handling apparatus) for storing a paper sheet inside a storage bag provided with an opening includes a first bonding unit (for example, each heating member) which thermally bond and seal a portion to be a bottom part of the storage bag held by the holding unit (for example, each holding member) when the paper sheet is stored in the storage bag and a second bonding unit (for example, each holding member) which bonds and seals an opening of the storage bag held by the holding unit with a bonding material (for example, each bonding part).
US10899482B2 Storage bag and paper-sheet processing device
A storage bag which includes an opening is to be suspended from a first holding section and a second holding section of a paper-sheet processing device. The storage bag includes a first attaching portion to be attached to the first holding section, and provided at an opening end of the storage bag, a second attaching portion to be attached to the second holding section, and provided at the opening end of the storage bag, a first sealing portion which is provided at a position below the first attaching portion, a second sealing portion which is provided at a position below the second attaching portion and which seals the opening by being joined with the first sealing portion, and a reinforcing member provided in either one of the first sealing portion and the second sealing portion.
US10899480B2 Fluid dispensing system with rotatable port assembly
A manifold port assembly includes a housing bounding a compartment and having an inlet port and a plurality of outlet ports formed thereon and communicating with the compartment. A carousel bounds a plurality of fluid paths that extend therethrough from a corresponding first end to an opposing corresponding second end, at least a portion of each fluid path being spaced apart from the housing and being radially enclosed by the carousel, the carousel being rotatably disposed within the compartment of the housing so that when the first end or the second end of each fluid path is aligned with the inlet port on the housing, the other of the first end or second end of each fluid path is aligned with a corresponding different one of each of the plurality of outlet ports.
US10899475B1 Transmission line tethered drone system
An unmanned aircraft system 100 built off of a purpose-built transmission infrastructure 300 with a power collector 400 riding along the infrastructure 300 connected to a tether 500 that is electrically connected to both the infrastructure 300 through the power collector 400 and also connected to an unmanned aircraft carrying associated electronics that are powered through the tether.
US10899468B2 Washer assembly with seal for lightning-protection fasteners and method of manufacture
A washer assembly including a metallic washer and a polymer seal. The metallic washer defines a cylindrical void and an axis therethrough. The polymer seal is attached to the metallic washer and is positioned radially inward thereof. The polymer seal includes a lower seal portion positioned at least partially within the cylindrical void and defining a counter-bore, and an upper seal portion extending axially from the lower seal portion. The lower seal portion is configured to engage, at the counter-bore, a fastener to form a seal to reduce escape of energized particles. The upper seal portion is configured to engage a counter-bore of a counter-bored nut to form a seal inside the counter-bored nut to reduce escape of energized particles.
US10899464B2 Moveable aircraft cowl and bypass section
The aircraft can have an aircraft engine and a cowl, the engine having an engine part disposed within the cowl, the cowl having a cowl section movable relative to a remainder of the cowl, the engine further having a gas path duct internal to the cowl with a first portion and a cooperating second portion, the second portion mounted to the cowl section, the cowl section moveable between a first position in which the first portion and the second portion are in fluid flow communication with one another and a second position in which the cowl section and the second portion are moved away from the first portion, wherein in the first position at least the second portion obstructs external access to the engine part and in the second position at least the second portion is displaced to permit external access to the engine part.
US10899456B2 Dynamically tilted seat pan
An apparatus for dynamically tilting a seatpan in an aircraft passenger seating assembly includes a seat frame, seatback, seat cushion, and cushion support structure (e.g., a seatpan), the seat cushion and seatpan together having a forward end and a rear end and together supporting a passenger occupying the seating assembly. Accelerometers may detect an inertial event such as a rapid deceleration that may cause the passenger to pitch forward; dynamic seatpan actuators (e.g., airbags or ballistic devices) connected to the accelerometers react to the inertial event by detonating, driving the seatpan and seat cushion upward. As a result, the head path of the passenger may be redirected upward, alleviating the risk of passenger injury and component damage. Additional airbags may react to the inertial event by tightening the passenger seatbelt.
US10899453B2 Vehicle with a simulated window feature
An example of operating a display system of a lavatory of a vehicle is provided. The method includes: (i) receiving, at a controller, information indicating that the lavatory is in use; (ii) in response to receiving the information, operating, by the controller, the display system in a first state while the lavatory is in use; (iii) determining, by the controller, that the lavatory is no longer in use; and (iv) in response to determining that the lavatory is no longer in use, operating, by the controller, the display system in a second state.
US10899449B2 Systems for automated carriage of items for delivery
Methods and systems for attaching and detaching an item satchel from an autonomous delivery unit. An attachment system includes an attachment system frame, and a satchel comprising a plurality of external pins. The attachment system also includes a plurality of hooks, mechanically attached to the frame, each hook including a first engagement surface and a second engagement surface, one or more electric actuators, mechanically attached to the frame, and mechanically connected to the plurality of hooks. Each of the first engagement surfaces engage a corresponding pin of the plurality of external pins at a first position between the horizontal and vertical positions, and each of the second engagement surfaces engage the corresponding pin of the plurality of external pins at the vertical position to secure an item satchel to an autonomous delivery unit.
US10899448B2 Apparatuses for releasing a payload from an aerial tether
Described herein are apparatuses for passively releasing a payload of an unmanned aerial vehicle (UAV). An example apparatus may include, among other features, (i) a housing; (ii) a swing arm coupled to the housing, wherein the swing arm is operable to toggle between an open position and a closed position; (iii) a spring mechanism adapted to exert a force on the swing arm from the open position toward the closed position; (iv) a receiving system of a UAV adapted to receive the housing, wherein the receiving system causes the swing arm to be arranged in the open position; and (v) a spool operable to unwind and wind a tether coupled to the housing, wherein unwinding the tether causes a descent of the housing from the receiving system, and wherein winding the tether causes an ascent of the housing to the receiving system.
US10899443B2 Systems and methods for variable blade pitch control
Systems and methods relate to a vertical takeoff and landing (VTOL) platform that can include a stator and a rotor magnetically levitated by the stator. The rotor and stator can be annular, such that the rotor rotates about a rotational axis. The stator can include magnets that provide guidance, levitation, and drive forces to drive the rotor, as well as to control operation of rotor blades of the rotor that can be independently rotated to specific pitch angles to control at least one of lift, pitch, roll, or yaw of the VTOL platform. Various controllers can be used to enable independent and redundant control of components of the VTOL platform.
US10899440B2 Rotor blade tip design for improved hover and cruise performance
A rotor blade for a rotary wing aircraft and a tip for the rotor blade. The rotor blade includes a blade root, a blade tip and a blade body that extends from the blade root to the blade tip. The blade tip includes: a continuously swept leading edge, a compound trailing edge, and a continuous anhedral.
US10899438B2 Seals for rotor system fairings
A fairing system, includes a hub fairing and a fixed fairing, such as a shaft fairing or a pylon fairing, both arranged about a rotation axis. A gap is defined between the hub fairing and the fixed fairing, and a seal assembly is axially interposed between the hub fairing and the fixed fairing. The fixed fairing and the hub fairing are both removably mounted to the seal assembly such that either or both of the fairings can be dismounted from the seal assembly without disturbing the seal assembly to provide access to components disposed within the fairing.
US10899427B2 Heated floor panel with impact layer
A heated floor panel assembly with an impact layer is made to absorb blunt force and protect a heating element inside the assembly. The assembly further includes a plurality of structural layer made of a reinforced polymer matrix, one or more core layer with a honeycomb or foam structure for absorbing shear stress, and a heating layer containing the heating element. The impact layer is a composite layer with a resin impregnated fiber matrix.
US10899422B2 Autonomous submersible offshore marine platform
It is an object of the present invention to provide a means of constructing an Autonomous fully-Submersible Offshore Marine Platform (ASOMP) of considerable warfighting or commercial capability which is mobile and can autonomously transport to a hazardous operating area in a low-observable reduced vulnerability manner, fully submerge to avoid the military or environmental threat hazard, hibernate until needed, perform fully submerged mobility and mission operations, surface and provide Barge and SWATH surface ship mobility and mission operations, resubmerge if the hazardous threat appears and relocate to a new operating area. Another object of the present invention is to provide a fully autonomous and submersible low-cost “lily-pad” that surfaces when called and provides a main deck platform at appropriate freeboard and seakeeping motions to function as a refueling landing zone and pier to extend the range of aircraft and marine vehicles operating in a high-threat environment.
US10899420B2 Conditional online-based risk advisory system (COBRAS)
An advisory system of a vessel that monitors variables of a vessel system inclusive of systems and subsystems that are used to operate the vessel. The advisory system may use machine-learning to learn from an operator (i) whether or not two variables are related to one another, and (ii) likelihood that a variable will reach a threshold, and, optionally, time until reaching the threshold. The system may receive operator feedback (i) to indicate whether the two variables are related to one another, and (ii) whether a behavior of the variable is normal or not normal. Thereafter, if a determination that the same two variables are related to one another and behaving in a similar manner, provide notification to the operator of the behavior. In response to determining that the variable is behaving (e.g., trending) in a similar manner that is not normal, providing a notification to the operator.
US10899418B1 Universal channel rod adjustable extension apparatus
A channel rod extension that provides access to the flexible cord through an opening of the extension, thereby allowing a user to quickly customize a length of the flexible cord and, accordingly, to quickly customize a dimension of the flexible cord-based system. The channel rod extension system includes an elongated extension with a discontinuous outer wall, forming a channel within which a flexible cord is received. A retainer made of a material having a high coefficient of friction surmounts the elongated extension to secure the flexible cord in place. To extend a dimension of the flexible cord-based system, the flexible cord is stretched and retained in place via the retainer, thereby elongating a dimension of the flexible cord-based system.
US10899414B2 Bicycle controller
A bicycle controller controls a motor in accordance with the riding environment of a bicycle. The bicycle controller includes an electronic control unit that is configured to control a motor that assists in propulsion of a bicycle in accordance with a manual driving force. The electronic control unit is further configured to set a response speed of the motor with respect to a change in the manual driving force input to the bicycle for a case within a predetermined period from a time at which the bicycle starts to travel to be different from the response speed for a case in which the predetermined period has elapsed.
US10899411B2 Straddle vehicle
A straddle vehicle includes: a body frame including a main frame extending rear-downward from a head pipe, a pivot frame extending downward from the main frame, and a lower frame which extends downward from the head pipe and extends rearward, and further, is connected to a lower portion of the pivot frame; a side stand which supports a vehicle body during parking; and a main step on which a foot of a rider is placed. A side stand bracket for supporting the side stand includes a first fixing portion connected only to the lower portion of the pivot frame and a second fixing portion connected only to a main step bracket for supporting the main step.
US10899410B2 Trifold bicycle frame
Disclosed herein is a folding bicycle comprising a handlepost joint and two joints in the mainbeam forward of the seat tube, wherein the pins of the hinges in the two mainbeam joints (i) are located on opposite sides of the mainbeam when viewed in a top view, and (ii) when the bicycle in folded, place the front wheel parallel to rear wheel and the wheel axles inline on the same lateral axis or on parallel lateral axes, wherein the wheels roll in parallel track.
US10899409B2 Saddled vehicle
A saddled vehicle includes: a vehicle body frame; an internal combustion engine supported at a lower portion of the vehicle body frame; a fuel tank supported at an upper portion of the vehicle body frame; and a canister. The canister is disposed around the fuel tank at a position lower than a seating portion of an occupant seat. A removable hermetic sealing cap or a one-way valve that prevents entry of rainwater from an outside is included in a drain pipe disposed at a lower portion of the canister. Accordingly, entry of rainwater into the canister is prevented with a simple structure.
US10899407B2 Saddle riding vehicle
Provided is a motorcycle including side cowls configured to cover a part of a vehicle body frame from sides, wherein each of the side cowls includes: an inner cowl, an outer cowl configured to cover the inner cowl from an outside in a vehicle width direction to form an air guide path configured to guide traveling air from a front side to a rear side between the inner cowl and the outer cowl, and an air flow conditioning member configured to generate downforce using traveling air directed from the inner cowl to an inner surface of the outer cowl in the vehicle width direction and flowing through the air guide path, and the air flow conditioning member is separated from the inner surface of the outer cowl in the vehicle width direction.
US10899398B2 Remote optical wind detection and aerodynamic control system for ground vehicle
An aerodynamic control system for a ground vehicle comprises a LiDAR module including at least one LiDAR sensor configured to obtain wind data upstream of the ground vehicle; a computing device; an aerodynamic device controller; and an aerodynamic device including a control surface. The computing device is configured to receive the wind data from the LiDAR module and generate output signals based on the wind data. The aerodynamic device controller is configured to receive the output signals from the computing device and generate control signals to control the aerodynamic device to adjust aerodynamic properties of the ground vehicle based at least in part the wind data. Changes to the configuration of the control surface may include increasing or decreasing a deflection angle of the at least one aerodynamic device. The aerodynamic device may include, e.g., a pneumatically actuated aerodynamic device or an electro-mechanically actuated aerodynamic device.
US10899397B2 Deployable fairing for use with vehicles
Systems and methods are disclosed for providing a deployable fairing system to a tractor trailer. The deployable fairing system includes an actuator used to extend the deployable fairing from an unextended configuration to an extended configuration to occupy a portion of a gap area that exists between a tractor and an attached trailer. The deployable fairing includes deployable upper and/or lower horizontal assemblies that are pivotally coupled to a frame attached to the tractor/cab, and two side panels that are pivotally coupled to one or both of the upper and lower horizontal assemblies. The deployable upper and lower horizontal assemblies and the two side panels fold in on one another along multiple hinged axes in the unextended configuration, and extend rearward from the top and sides of the tractor in the extended configuration to cover a portion of the gap. The fairing may advantageously flair from front to the rear.
US10899394B2 Structural reinforcement member for a vehicle body
A vehicle body includes a structural member having an inner surface defining an elongated cavity. The structural member includes an outer panel member joined to an inner panel member. A reinforcement member is positioned in the cavity wherein a gap is provided between the reinforcement member and the inner surface of the structural member. The reinforcement member includes an outer section, an inner section and a tension web interposed between and contacting the outer section and inner section. The outer section faces the outer panel member and the inner section faces the inner panel member. The tension web is secured to the outer panel member and inner panel member. An adhesive secured to the reinforcement member is activatable to expand toward the inner surface of the structural member to define a joint between the reinforcement member and the structural member and to at least partially fill the gap.
US10899384B2 Trailer reverse assist with follow-me system
A method for maneuvering a vehicle-trailer system in a reverse direction is provided. The method includes receiving images from a camera positioned on a rear portion of the trailer. The method includes: identifying one or more guide representations within the received images; and transmitting the received images to a user interface. The method also includes receiving from the user interface, an indication of a guide representation from the one or more guide representations. The method includes determining a path that includes maneuvers configured to move the vehicle-trailer system along the path to follow the guide associated with the identified guide representation while maintaining a minimum distance from the guide positioned behind the trailer. The method also includes transmitting to a drive system of the vehicle, one or more commands causing the vehicle-trailer system to autonomously move the vehicle-trailer system along the vehicle-trailer path in the reverse direction.
US10899381B2 Steering control device and control method for steering control device
A steering device is provided to perform a safe transition from an automatic driving mode to a manual driving mode when necessary. When it is determined necessary to transition from the automatic driving mode to the manual driving mode during the automatic driving mode, a transition period before an end time point of the automatic driving mode is set, a driving operation reliability indicative of whether or not it is possible to perform the transition is determined, and the transition when it is determined that it is possible to perform the transition to the manual driving mode during the automatic driving mode. Consequently, the transition can be controlled so that transition is not performed instantly, such as, for example, in a case where a driver is not driving during the automatic driving mode and is not accustomed to manual driving.
US10899379B2 Energy absorbing device for internally collapsing steering column assembly
An energy absorption strip (40) having a generally elongated body portion (46), a first end (42) and a curved portion (44) between the first end (42) and the generally elongated body (46) portion that forms and angle between the first end (42) and the generally elongated body portion (46). The energy absorption strip (40) is adapted to be carried within a steering column assembly (10) and absorb energy by plastic deformation during translation of a column tube (20) during an impact exceeding a threshold load. A steering column assembly (10) including the energy absorption strip (40) is also contemplated.
US10899378B2 Steering column device working together with airbag system
A steering column apparatus may include a moveable unit assembled with the steering wheel at a front end portion thereof to be driven back and forth; a guide unit mounted to a rear end portion of the moveable unit to guide back and forth movement of the moveable unit; a drive unit provided in the guide unit to drive the moveable unit; and an actuator unit configured to fix the drive unit to the guide unit, and provided with an inflator triggered in cooperation with an operation signal of the airbag, to be operated to generate a propulsive force in a forward direction thereof.
US10899372B2 Railcar bogie
A railcar bogie includes: a cross beam supporting a carbody of a railcar; an axle box including a bearing accommodating portion accommodating a bearing rotatably supporting a wheelset; a plate spring extending in a car longitudinal direction while supporting a car width direction end portion of the cross beam; and a receiving member provided above the axle box and supporting a car longitudinal direction end portion of the plate spring, an attachment hole being formed at a car longitudinal direction outside portion of the receiving member, a lifting fitting used to lift the bogie being attached to the attachment hole.
US10899369B2 Electric rail carriage
An electric rail carriage is described. The electric rail carriage may include a train carriage. The train carriage may be arranged to be powered by at least one power module, which is arranged to generate electric power. The carriage may include a main chassis, and at least one power module bay located underneath the main chassis. A power module can be removably located and secured within the power module bay, such that the power module is supported underneath the main chassis. A method of installing the power module into a power module bay is described.
US10899367B2 Systems and methods for data management
A method for data management for an autonomous vehicle may include transmitting a polling request to a first server to obtain a task. The task may be a remote task request, and the task may be associated with obtaining, from the autonomous vehicle, data related to one or more subjects via a mobile network. The method may also include receiving the task from the first server based on the polling request. The method may also include obtaining the data based on the task. The method may also include transmitting the data to a second server via the mobile network.
US10899366B2 Method to assist control of a vehicle assistance system
A method to assist with control of a vehicle in road traffic is provided. Parameters including a distance, direction and speed of other road users are detected. The parameters are used to determine a strategy for the driver to start an intended control action. A time window is determined that enables the driver to start the intended control action and is displayed in a graphical representation to scale to the driver through a driver-vehicle interface.
US10899364B2 Autonomous vehicle system
An operator interface for controlling one or more autonomous vehicles. The operator interface is configured to generate a graphical rule creation interface (GRCI) for an operator. The GRCI is displayable to and interactive with the operator for allowing the operator to input instructions. The operator interface is further configured to compile a rule set for governing operations of the one or more autonomous vehicles from instructions inputted by the operator via the GRCI and to upload the rule set to memory units of each of the one more autonomous vehicles to supersede previously installed rule sets.
US10899361B2 Moving object controlling device, moving object controlling method, and computer readable medium
A moving object controlling device (10) determines, when malfunction of an instrument such as a processor (11) mounted in a moving object (100) is specified, control contents with respect to the moving object (100) according to malfunction contents such as a level of the specified malfunction and a peripheral situation of the moving object (100) such as a movement place of the moving object (100) and a movement environment that influences movement of the moving object (100). Then, the moving object controlling device (10) controls the moving object (100) according to the determined control contents.
US10899353B2 Method for operating a vehicle/trailer unit, vehicle/trailer unit, towing vehicle, and implement
The invention relates to a method for operating a vehicle/trailer unit, an appropriately designed vehicle/trailer unit, as well as a towing vehicle and an implement for such a vehicle/trailer unit, with the vehicle/trailer unit having a towing vehicle and an implement. The towing vehicle has a combustion engine and a first machine that can be operated as a prime mover, as well as a first axle that can be driven by means of the combustion engine, with it being possible for the combustion engine to be driven by means of the first machine. The implement has a second machine that can be operated as a work machine and a second axle that is mechanically coupled with the second machine. When the vehicle/trailer unit is in overrun mode and/or braking mode, the vehicle/trailer unit can be operated in a first operating mode in which the second machine is operated as a work machine and driven by means of the mechanical kinetic energy of the second axle, while the first machine is operated as a prime mover and drives the combustion engine, with it being possible for at least a portion of the energy generated by the second machine to be utilized to drive the first machine.
US10899351B2 Hybrid powertrain system and operation with transfer case in low gear
A hybrid powertrain includes a torque provider, an automatic transmission without a torque converter, and a transfer case configured for providing four wheel drive low range. A controller receives a signal indicative of the transfer case being in low range and determines if brake pedal torque is indicative of a brake pedal being released and, if so, commands engagement of a launch clutch of the transmission up to maximum creep torque capacity at a predetermined maximum gradient. The controller determines when torque provider speed is synchronized with vehicle creep speed, and upon such determination, controls the launch clutch to fully engage to a lock up state to mimic behavior of engagement of a manual transmission gear when the hybrid powertrain is in low range to thereby substantially eliminate a time lag associated with automatic transmissions having a torque converter or a constantly slipping launch clutch.
US10899350B2 Vehicle handling system and method
A method and system include a vehicle system including a plurality of vehicles. The system includes a handling unit comprising a communication device and a controller. The communication device receives first position data for a first vehicle of the vehicle system and second position data for a second vehicle of the vehicle system relative to a route on which the vehicle system is traveling. The controller determines that the first vehicle is entering into a curved portion of the route, and generates a control signal based on the first and second position data. The control signal changes an operating parameter of at least one of the first or second vehicles to control a separation distance between the vehicles or a deviation distance between respective travel paths taken by the first and second vehicles through the curved portion of the route.
US10899349B2 Centering a vehicle in a lane using environmental information to correct a predicted trajectory
A method and system for centering a vehicle in a lane. The system includes an electromagnetic radiation sensor, a motion sensor, a steering system, and an electronic controller. The electronic controller is configured to receive environmental information regarding an environment external to the vehicle from the electromagnetic radiation sensor and to receive a first motion of the vehicle from the motion sensor. The electronic controller is also configured to determine a predicted position of the vehicle based the first motion of the vehicle and the environmental information, store the predicted position, compare the predicted position to a desired position of the vehicle to generate and send a corrective signal to the steering system. The electronic controller is further configured to determine a current position of the vehicle, compare the current position with the predicted position to generate a difference, and calibrate the motion sensor based on the difference.
US10899347B2 Method and device for operating a vehicle
A method for a vehicle, by which it is determined whether a further vehicle located in the surroundings of the vehicle is operated in an at least semi-automated manner. The method includes detecting at least one parameter of the further vehicle and determining, on the basis of the at least one parameter, whether the further vehicle is operated in an at least semi-automated manner.
US10899345B1 Predicting trajectories of objects based on contextual information
Aspects of the disclosure relate to detecting and responding to objects in a vehicle's environment. For example, an object may be identified in a vehicle's environment, the object having a heading and location. A set of possible actions for the object may be generated using map information describing the vehicle's environment and the heading and location of the object. A set of possible future trajectories of the object may be generated based on the set of possible actions. A likelihood value of each trajectory of the set of possible future trajectories may be determined based on contextual information including a status of the detected object. A final future trajectory is determined based on the determined likelihood value for each trajectory of the set of possible future trajectories. The vehicle is then maneuvered in order to avoid the final future trajectory and the object.
US10899343B2 Parking assistance method and parking assistance device
A parking assistance method of a parking assistance device for generating a peripheral image indicating a periphery of a vehicle as viewed from above to detect an unoccupied parking space, and displaying, on the peripheral image, an assistance image indicating that the detected unoccupied parking space is an available parking space, determines whether the vehicle intrudes on the unoccupied parking space. The parking assistance method inhibits the assistance image from being displayed on the unoccupied parking space on which the vehicle is determined to intrude in the peripheral image.
US10899335B2 Methods and systems for a hybrid vehicle
Methods and systems are provided for operating a driveline of a hybrid vehicle that includes an internal combustion engine, an electric machine, and a transmission are described. In one example, the engine is started and coupled to the driveline via closing a clutch of a dual clutch transmission. Speed of the engine and clutch pressure are controlled to reduce driveline torque disturbances and provide a desired wheel torque.
US10899334B2 Torque limiting clutch
A torque limiting clutch that includes an input member and at least two output members is provided. The input member is configured to receive torque. Each output member is in operational communication with the input member to transfer torque between the input member and each output member. Each output member is configured to slip the operational communication with the input member when a torque above a set torque limit is encountered. Further wherein the slip of the operational communication between the input member and one output member of the at least two output members is independent of the operational communication between the input member and any other output member of the at least two output members.
US10899324B2 Braking control device for vehicle
A braking control device generates a force for pressing a friction member against a rotating member fixed to a wheel of the vehicle via an electric motor controlled by a controller in accordance with an operation amount of an operation member. A pressing force sensor detects a pressing force actual value, and a rotation angle sensor detects a rotation angle actual value of the motor. The controller determines whether an operating state of the pressing force sensor is appropriate. When the operating state is appropriate, the motor output is adjusted based on the pressing force actual value, a correlation between the pressing force actual value and the rotation angle actual value is stored, and a conversion calculation map is created based on the correlation. When the operating state is not appropriate, the motor output is adjusted based on the rotation angle actual value and the conversion calculation map.
US10899319B2 Fluid delivery system for a vehicle wash system
A vehicle wash system includes a vehicle treatment component located adjacent a vehicle treatment area for treating a vehicle exterior. The system includes at least one fluid delivery nozzle associated with the vehicle treatment component. The fluid delivery nozzle is in communication with a source of fluid and includes a first state of operation with a first flow rate and a second state of operation with a second flow rate. The first and second flow rates are different. The system allows the fluid flow through the fluid delivery nozzle to be selectively varied while a vehicle is disposed in the vehicle treatment area adjacent the vehicle treatment component.
US10899316B1 Automobile access and intrusion detection
A vehicle theft-prevention apparatus can include at least one computing device coupled to a first sensor and a second sensor that are configured to sense a first and a second type of measurement in a vehicle, respectively. The at least on computing device can be configured to read a plurality of measurements of the first type of measurement from the first sensor at a predetermined frequency. In response to one of the plurality of measurements exceeding a predetermined threshold, the at least one computing device can read at least one measurement from the second sensor. Based on the at least one measurement from the second sensor, the at least one computing device can determine that a person has entered the vehicle.
US10899312B2 Safety belt retractor, a vehicle safety belt and a vehicle
A safety belt retractor, a vehicle safety belt with the safety belt retractor and a vehicle with the vehicle safety belt are provided. The safety belt retractor is provided, on an end segment thereof, with a pre-tensioning, force-limiting and decoupling device that comprises a safety belt reel (1), a driving element (2), a sleeve (3) and an energy absorbing disc (4). The safety belt reel (1) is provided with a first recess (10) and a second recess. A first helical surface (9) is arranged in the first recess (10), and the driving element (2) is provided with a first projection (21) having a second helical surface acting together with the first helical surface (9). The sleeve (3) is provided with a second projection (31) mounted in the second recess. Under a predetermined load, the second projection (31) is cut off, such that the energy absorbing disc (4) is plastically deformed due to squeezing. The safety belt retractor achieves on the same end segment, the pre-tensioning, force-limiting and decoupling functions as well as a compact structure.
US10899311B2 Passenger restraining device for vehicle
A passenger restraining device for a vehicle having a three-point seatbelt device, a shoulder belt extending from above, a seat transverse direction one end side of a seatback of a vehicle seat toward a lower portion; a belt guide at an upper portion side of the seat transverse direction one end side of the seatback, through which the shoulder belt is inserted, that's disposed along a restrained surface of a passenger seated in the vehicle; a fixing portion fixes a rear end portion of the belt guide to a seat shoulder opening at the seat transverse direction one end side of an upper portion of the seatback; and a front side portion at a length direction front side of the belt guide, in a usual state, disposed further toward a vehicle front side than a collarbone of the passenger seated in the vehicle, and structured to be hard to bend.
US10899309B2 Airbag
An airbag is formed by joining outer edges of an occupant-side wall and a vehicle-side wall each of which is made of a base cloth having flexibility. The occupant-side wall and vehicle-side wall are equal in circumferential length of the outer edge. The occupant-side wall includes a recessed region for receiving a head of a vehicle occupant and an annular raised region that surrounds the recessed region. At least one of the occupant-side wall and the vehicle-side wall includes at least one shortening region that reduces a circumferential length of an outer edge of the base cloth.
US10899306B2 Side-impact restraint system
A restraint system includes a side curtain airbag and a tether. The side curtain airbag includes an outboard side and an inboard side, and the inboard side including a protrusion. The tether includes a central seam, a first extension attached at the outboard side, a second extension attached at the inboard side above the protrusion, and a third extension attached at the inboard side below the protrusion. The extensions are attached to each other at the central seam.
US10899295B2 Using data collected by a personal electronic device to identify a vehicle
Apparatus and methods are disclosed for identifying a vehicle using data collected by a personal electronic device residing in the vehicle during its operation. By enabling the vehicle to be identified using data collected by the personal electronic device, embodiments of the invention may allow other information captured by the personal electronic device relating to the user's operation of the vehicle to be associated with the vehicle.
US10899294B2 Grommet assembly
A grommet assembly includes an inner member having a first half portion and a second half portion, each having a body portion to be fitted into a mounting hole of a panel, a panel engagement portion configured to be engaged with an opening edge of the mounting hole, a grommet to be mounted to a rear side of the inner member and a first protruding part protruding from a rear side of the first half portion toward a rear wall of the wire housing portion. The inner member is to be dividable into the first and second half portions along a fitting direction of the body portion to the mounting hole. The first protruding part includes a first hook portion bent back at a protruding end of the first protruding part and includes a first pressing support portion including the protruding end of the first protruding part.
US10899292B2 Method of manufacturing insulator
A method of manufacturing an insulator is provided. The insulator includes a lower member and an upper member. The lower member is placed as a second flange of the lower member is fixed in position. The upper member is then disposed on the lower member as the second flange of the upper member is fixed in position. Accordingly, the first flange of the upper member and the first flange of the lower member abut each other, and the second flange of the upper member and the second flange of the lower member abut each other. Then, the first flange of the upper member and the first flange of the lower member are swaged, and then the second flange of the upper member and the second flange of the lower member are swaged.
US10899291B2 Vehicle rear liftgate seal
A liftgate seal is disclosed for a vehicle including a vehicle roof and a vehicle liftgate having a liftgate window pane, the liftgate seal includes a base wall, adapted to be secured to an interior surface of the window pane, and a channel structure including a first wall connected to the base wall and a second wall angled relative to the first wall. The second wall includes a distal end adapted to contact a rear edge of the vehicle roof when the vehicle liftgate is closed position thereby sealing a gap between the rear edge of the vehicle roof and the liftgate window pane.
US10899287B1 Weighted bed liner
A vehicle bed liner for providing additional weight to a vehicle includes a support layer including a base material having a thickness, where the thickness of the base material is substantially constant across the entirety of the base material, a weight-receiving compartment within the support layer, and a weight-storing article within the weight-receiving compartment adapted to receive a plurality of weight-providing articles, wherein the plurality of weight-providing articles are capable of being positioned in the weight-storing article to thereby provide additional weight to a vehicle.
US10899274B2 Illumination of a vehicle storage compartment through electroluminescent material
An electroluminescent assembly for a vehicle storage compartment and a method for installing the same on a vehicle storage compartment includes a transparent panel and a door, each at least partially defining the storage compartment. Light emitted by the electroluminescent assembly illuminates the interior of the storage compartment, and is also transmitted through the transparent panel to thereby illuminate a portion of the vehicle that is at an exterior of the storage compartment.
US10899272B2 Vehicle light with dual projection film
A vehicle light module, a headlight assembly, and a method for communicating information are provided. The vehicle light module includes a panel having a transparent state and an opaque state; and a projector operable to project a visual representation toward the panel. The visual representation is displayed on the panel when in an opaque state and on a second surface when in a transparent state.
US10899269B2 Lamp control device and lamp assembly
A common lamp driving circuit is configured to supply current. A switching circuit is configured to selectively supply the current to either a first lamp or a second lamp that are of different types. A processor is configured to control the switching circuit such that a state in which the current is supplied to the first lamp and a state in which the current is supplied to the second lamp are repeated.
US10899268B1 Lamp having built-in sensor, lamp assembly, blind-spot detection system, and blind-spot detection method
A lamp having a built-in sensor includes a lamp housing having a lamp opening on one side thereof in a longitudinal direction of the lamp, a light-transmitting outer glass that covers the lamp opening, a light guide that is disposed on an inside surface of the lamp housing and that emits light, an inner glass located ahead of the light guide inside the lamp housing with respect to the longitudinal direction, and a sensor that is disposed inside the lamp housing and located ahead of the inner glass with respect to the longitudinal direction and that senses a surrounding object.
US10899266B2 Snow removal machine
A snow removal machine capable of illuminating, with a light projector, a dropped position of snow that varies depending on a direction of a chute guide. A working machine as a snow removal machine includes a machine body, and a chute that is provided on the machine body, and throws away snow. The chute includes a chute main body extending upwardly from the machine body, and a chute guide that is pivotably provided on a distal end portion of the chute main body, and adjusts a snow throwing direction that is an up-down direction of the snow to be thrown, the chute guide is connected to the chute main body side through a link, and the link is provided with a light projector so as to be capable of illuminating a dropped position of the snow to be thrown.
US10899264B2 Vacuum insulator in a storehouse and methods of making and using the same
Disclosed is a vacuum insulator comprising: a heat diffusion block placed in a third space; a thermoelectric module coming into contact with the heat diffusion block so as to exchange heat therewith, and placed in the third space; and a heat sink exchanging heat with the thermoelectric module and placed in a first space or a second place. According to the present invention, high heat-insulation performance and heat-transfer performance can be obtained.
US10899258B2 Armrest for vehicle seat and vehicle seat comprising such an armrest
An armrest includes an armrest arm having an upper support surface forming a support for the forearm of an occupant of the vehicle seat, and a user interface having at least one display portion of flattened shape, having a front face comprising a screen and a rear face formed by a shell. The user interface is mounted on the armrest arm so as to be movable between a retracted position where the screen is inaccessible and an extended position where the screen is accessible. In the retracted position of the user interface, the shell is integrated with the upper support surface of the armrest arm, and in the extended position of the user interface, the screen is at least partially projecting above the upper support surface of the armrest arm.
US10899257B2 Automotive foamless seat made from flexible material
A foamless seating assembly includes a frame having an inner support member and an outer support member. A first plurality of flexible straps extend about the inner support member of the frame. A second plurality of flexible straps extend about the outer support member of the frame. At least one flexible strap of the second plurality of flexible straps of the outer support member are adjacent to at least one flexible strap of the plurality of flexible straps of the inner support member. A tension assembly is operably coupled with the flexible straps and configured to apply tension to the straps simultaneously.
US10899256B2 Seat assemblies for temporarily attaching a seat assembly to a vehicle
A seat assembly, for a vehicle having a frame member, includes a seat back, a seat cushion, and a seat bracket. The frame member extends along a floor of the vehicle and includes a bore. The seat cushion is pivotally coupled to the seat back for movement between a use position and a raised position. The seat bracket is coupled to at least one of the seat back and the seat cushion. The seat bracket includes a pin that extends downwardly in a vehicle vertical direction. The pin engages with the bore to temporarily attach the seat cushion and the seat back to the frame member on the floor of the vehicle and inhibit a rotation of the seat assembly in a vehicle forward direction when the seat cushion is in the raised position due to the engagement of the pin extending through the bore of the frame member.
US10899252B2 Child safety seat with belted pivot link
The invention relates to a child safety seat (100) adapted to be secured with a safety belt (40) of a vehicle, comprising a seat shell (20) for receiving a child; and a seat base (10) for being placed on a seat of the vehicle. The seat base (10) comprises a base member (1) coupled to the seat shell (20); a pivoting component (2) connected pivotably to the base member (1); and an engaging member (3) configured to engage with the safety belt (40) of the vehicle, wherein the engaging member (3) is coupled to the pivoting component (2) such that a movement of the engaging member (3) in a certain direction relative to the base member (1) causes the pivoting component (2) to pivot away from the base member (1).
US10899241B2 Connecting element and connecting apparatus for electrically connecting a cable to an electrical device of a motor vehicle
A connecting element for electrically connecting a cable to an electrical device of a motor vehicle includes a housing in which at least two electrical contacts are at least partially accommodated and a passage which extends from a first opening of the housing, through the housing, to a second opening of the housing and through which a coolant can flow. In order to allow an electrical connection which satisfies relatively stringent requirements, the electrical contacts are thermally coupled to the passage for active cooling by the coolant.
US10899240B2 Intelligent pod management and transport
A passenger transport system has a pod adapted to carry passengers or articles and a first attachment interface, a plurality of transport vehicles, each adapted to couple to the passenger pod, a first entry station adapted to load a passenger or articles into the pod, a plurality of exchange points, and a final destination station adapted to unload the passenger or articles from the pod carried by the transport vehicle. The pod with a passenger or articles is loaded at the first entry station travels on transport vehicles between individual ones of the exchange stations, until arriving at the final destination station where the passenger or the articles are unloaded, the passenger or articles remaining in the pod through all exchanges between transport vehicles.
US10899236B2 Drive system for a transportation system
A transport system including at least one guideway, at least one levitation generator, at least one lifting member, at least one drive generator, and at least one drive member is presented. The at least one guideway, at least one levitation generator, at least one lifting member, at least one drive generator, and at least one drive member can each be implemented with other systems. The at least one drive generator is configured to: generate a driving magnetic flux; move with a corresponding at least one drive member; and be driven relative to the at least one drive member by the driving magnetic flux. The at least one levitation generator can be configured to: generate a levitating magnetic flux; move within a corresponding at least one lifting member; and elevate above a rest position relative to the at least one lifting member in response to the levitating magnetic flux.
US10899234B2 Non-contact electric power transmission system, charging station, and vehicle
A power source ECU transmits a first message for inquiring whether or not a vehicle is parked at a location provided with a power transmission device, after full-scale power transmission is completed. A vehicle ECU transmits a second message for informing that the vehicle is parked, when it receives the first message. When the power source ECU does not receive the second message for informing that the vehicle is parked after transmitting the first message, the power source ECU determines that the vehicle is not parked at the location provided with the power transmission device.
US10899233B2 Power converter for electric vehicle
A vehicle having a high voltage power source for operating high voltage devices, such as in-wheel electric motors for propelling the vehicle. The high voltage in-wheel electric motors are controlled by dedicated controllers paired with the devices and requiring low voltage power. The vehicle includes one or more converters paired with the dedicated controller(s) and for converting high voltage power to low voltage power suitable for powering the controllers.
US10899231B2 System and method for avoiding inrush current in a vehicle microgrid
A vehicle includes an inverter configured to power an external device. The vehicle further includes a controller programmed to cause the inverter to output a voltage at a steady-state amplitude and a steady-state frequency and, responsive to detecting an inrush current event in progress that is caused by the external device, operate the inverter to reduce the voltage to prevent an overcurrent. The controller is programmed to identify the type of load connected and return the voltage to the steady-state amplitude and steady-state frequency based on the type of load.
US10899226B2 Vehicle trim element comprising a deformable part for delimiting a functional space
The vehicle trim element includes a body defining the outer surface of the trim element, said outer surface including at least one main area and at least one secondary area, the body including at least one deformable part forming a flap movable in the secondary area between a first stable position, in which said flap extends substantially in the continuation of the main area, and at least one second stable position, in which the flap forms a non-zero angle with the main area so as to extend protruding from said main area. In the second position, the flap forms a wall on one side of which a functional space extends opposite the secondary area.
US10899225B2 Vehicle control device, vehicle control method, and storage medium
A vehicle control device includes a first calculator configured to calculate a first operation amount, a second calculator configured to calculate a second operation amount, and a controller configured to cause the operation amount of one driving force control to be changed to zero in a predetermined time, causes the operation amount of the other driving force control to be increased to a target operation amount in the predetermined time, and controls a driving force of the vehicle on the basis of the operation amount of one driving force control and the operation amount of the other driving force control during the predetermined time.
US10899224B2 Hub motor arrangement or vehicle with hub motor arrangement
A ride-on vehicle, such as for a child, includes a vehicle body and one or more wheels that support the vehicle body relative to a surface. At least one of the wheels includes a hub motor arrangement that provides a drive torque for propelling the vehicle. The hub motor arrangement includes a housing defining an interior space. An axle or other mounting element(s) define an axis of rotation of the housing. Preferably, the axle or other mounting element(s) do not pass completely through the housing. A motor drives the housing through a transmission. Preferably, the motor is a standard, compact motor that is positioned on the axis of rotation and can be laterally offset from a central plane of the housing. In some embodiments, a traction element is carried directly by the housing.
US10899215B2 Hydraulic mount apparatus
A hydraulic mount apparatus comprises a housing having an upper portion and a lower portion and defining a housing chamber. A partition member disposed therein and divides the housing chamber into a pumping chamber and a receiving chamber. A decoupler including a magnetic actuator is attached to the partition member. A moving member is disposed in the pumping chamber and attached to the decoupler. The moving member includes at least two magnetic inserts disposed therein, spaced from one another, to move the moving member from a first position to a second position in response to a magnetic field. The first position is defined as the moving member being spaced from the decoupler. The second position is defined as the moving member being attached to the decoupler.
US10899214B2 Electric powertrain system for heavy duty vehicles
A battery assembly for an electric vehicle is provided that includes a housing, one or more battery units, and a mounting system. The one or more battery units are disposed within the housing. The mounting system is disposed adjacent to a top surface, e.g., on a planar top surface or within an upwardly oriented concavity. The mounting system has a frame member bracket and a housing bracket system. The housing bracket system includes a housing bracket, a load member and a vibration isolator. The housing bracket is configured to be coupled to the frame member bracket. The load member has a first portion disposed adjacent to an upper surface and a second portion disposed along a lateral portion of the housing. The vibration isolator is disposed between the load member and the housing bracket. The vibration isolator is configured to reduce load transmission from the frame member of the vehicle to the housing.
US10899213B2 Vehicle battery support
A vehicle includes a vehicle frame. The vehicle includes a subframe connected to the vehicle frame. The vehicle includes a tray supported by the vehicle frame. The vehicle includes a V-shaped member having an end at the tray and a pair of legs extending from the end in a vehicle-forward direction to the subframe.
US10899211B2 Battery system, housing and vehicle including battery system
A battery system for use in a vehicle is disclosed. The battery system includes a tray having a plurality of battery receptacles. A plurality of batteries are also provided, each battery in the plurality of batteries being received in a battery receptacle. A conductive layer in electrical communication with the plurality of batteries and a terminal for electrically coupling to a vehicle are also provided in the battery system. A cover interlocks with the tray. The cover carries a computer and a diagnostic identification system for the plurality of batteries. A housing for a battery system and a vehicle including a battery system are also disclosed.
US10899209B2 Vehicle cab protective top cover system
A vehicle cab protective top cover system including a platform assembly having a top-surface, a bottom-surface, and a magnet fastener system. The platform assembly is defined by the top-surface and the bottom-surface forming a thickness. The magnet fastener system is embedded within the platform assembly and may removably fasten the platform assembly to a metal surface of a top portion of a cab of a vehicle. The platform assembly forms a barrier and provides a protective top cover for the top portion of the cab of the vehicle.
US10899208B2 Motorized windshield sunshade
A motorized sunshade to optionally cover at least a portion of a windshield of an automobile, the motorized sunshade including a roller rod removably disposed on a top edge of an exterior surface of the windshield, a rolling shade disposed within an interior portion of the roller rod to cover the windshield in response to a movement of the rolling shade from a first position to a second position and to expose the windshield in response to a movement of the rolling shade from the second position to the first position, and a plurality of tracks disposed at side edges of the windshield and removably connected to the roller rod, such that the rolling shade slides between and at least partially within each of the plurality of tracks.
US10899201B2 Method of making an impact beam structure for a vehicle door
A method includes molding an outer impact beam made of carbon fiber reinforced plastics (CFRP) and separately molding an inner impact beam made of CFRP. The outer impact beam and the inner impact beam are coupled to each other to form an impact beam and the impact beam is coupled to an inner panel of a vehicle door.
US10899199B2 Control method and system for air-conditioner water chilling units and air conditioning system
This disclosure provides a control method and control system for two or more air-conditioning water chilling units, and air conditioning system. The control method includes: receiving at least one standby request generated by at least one air-conditioner water chilling unit of the two or more air-conditioning water chilling units based on a standby condition; determining whether or not two or more standby requests are received; generating standby sequence numbers of the air-conditioning water chilling units that send the standby requests according to the standby requests in case where two or more standby requests are received; and closing the air-conditioning water chilling units that send the standby requests according to a preset rule based on the standby sequence numbers.
US10899198B2 Air conditioner for vehicle
A heater core for performing heat exchange between a coolant and ventilation air to be blown to the interior of a vehicle so as to heat the ventilation air is disposed in a water circulation circuit for circulating a coolant in an engine EG for outputting driving force necessary to move the vehicle. When the temperature of the coolant discharged from the engine EG is low, a heat transport refrigeration cycle device, serving as a heat transport unit for absorbing heat from a downstream coolant at a position downstream more than the heater core and dissipating the heat absorbed from the downstream coolant to an upstream coolant at a position upstream more than the heater core, is operated to increase the temperature of the coolant introduced into the heater core until the temperature of the coolant reaches the temperature necessary to heat the interior of the vehicle, without operation of the engine EG.
US10899194B2 Air-conditioning control apparatus
An air-conditioning control apparatus for a vehicle capable of unmanned driving includes a determining section that is configured to determine whether an occupant is in the vehicle and an output section that is configured to execute an air-conditioning control based on a determination result by the determining section. The output section is configured to execute the air-conditioning control based on ride schedule information indicating a length of time until an occupant rides in the vehicle when the vehicle is determined to be in an unmanned state.
US10899191B2 Heating and cooling system for vehicle
A heating and cooling system for a vehicle may include: a refrigerant line provided to pass through a compressor, an interior heat exchanger for interior air-conditioning, an air-cooled condenser, and an evaporator core for interior air-conditioning, the refrigerant line configured such that a refrigerant flows therethrough; a coolant line provided to pass through a high-voltage battery core, an electric part core for an electric part, and a radiator for the electric part, the coolant line configured such that a coolant flows therethrough; and a heat exchanging part configured to exchange heat between the refrigerant flowing between the interior heat exchanger and the air-cooled condenser, and the coolant flowing between the electric part core and the radiator.
US10899185B2 Chassis arm with damper connection section and method for production of a chassis arm
The invention relates to a chassis arm for a motor vehicle, having a first end section for connection to a chassis support, a second end section for connection at a wheel end, and a damper connection section exhibiting at least one bearing eye for connecting a damper. The bearing eye is assigned at least one installation aid with a support surface for the damper. The installation aid is formed integrally with the chassis arm, wherein the installation aid in the form of a tab is cut free from the base material of the chassis arm and converted to a body section of the chassis arm, and wherein at least a part of the tab is designed as a support surface for the damper. The invention also relates to a method for producing a chassis arm, in particular a spring control arm for a motor vehicle.
US10899183B2 Systems and methods for magnetoelastic hitch receiver force detection
Systems and methods for magnetoelastic hitch receiver force detection are disclosed. An example vehicle includes a chassis, a trailer hitch receiver configured to receive a trailer hitch arm along an axis, a first pin having a first magnetic field, the first pin disposed above and perpendicular to the axis, a second pin, the first pin and the second pin coupling the trailer hitch receiver to the chassis and a first sensor configured to detect changes in the first magnetic field.
US10899182B2 Tractor hitch
In accordance with one series of embodiments of the current disclosure, there is provided a tractor hitch system for hitching a tractor to a trailing implement. The tractor hitch system comprises a base, an actuator, a pin and a lever arm. The base is configured to be mountable on a drawbar of the tractor. The actuator is movable between a first position and a second position. The lever arm is attached to the base, connected to the actuator, and attached to the pin. The attachment of the lever arm to the pin allows the pin to pivot and move laterally with respect to the lever arm such that, when the actuator is in the first position, the pin engages the drawbar so as to be able to couple the tractor to the trailing implement, and when the actuator is in the second position, the pin is disengaged from the drawbar so that the tractor is not coupled to the trailing implement.
US10899179B2 Motorcycle tire and tire set
A tire used for the motorcycle tire and tire set includes: a crossing groove and a non-crossing groove. A groove group of the crossing groove and the non-crossing groove is repeatedly provided in tire circumferential direction so that adjacent groove groups are symmetric with respect to a tire equatorial plane. First, second, and fifth groove portions extend toward one side in tire circumferential direction and third and fourth groove portions extend toward the other side in tire circumferential direction. A first bend portion is located in a shoulder region nearer the one tread edge, a second bend portion is located in a middle region nearer the one tread edge, and a third bend portion is located in a middle region nearer the other tread edge. Inclination angles of the second, fourth and fifth groove portions are each larger than an inclination angle of the first groove portion.
US10899174B2 Wheel end assembly having a compression ring and method of assembly
A wheel end assembly having a steering knuckle, a hub, and a compression ring. The steering knuckle may have an opening that may extend around a spindle. The hub may be rotatably disposed on the spindle. The compression ring may be disposed on the hub and may be at least partially disposed in the opening.
US10899171B2 Low impact turf wheel
A low impact turf wheel having a wheel rim including an inner and outer surface, a plurality of pegs extending radially outward from the outer surface of the wheel rim, wherein the plurality of pegs maintain the wheel rim above an area of turf, and a hub. A turf wheel having a wheel rim having an inner and outer surface, a plurality of pegs extending radially outward from the outer surface of the wheel rim, wherein the peg comprises a stem, a collar and a lug, and wherein the lug includes a limited surface area to provide a ground contacting tread, and a hub.
US10899168B2 Device for protecting and preserving a substance in a container
Disclosed is a device for protecting and preserving a substance in a container. The device may include a plurality of overlapping sectors capable of rotating about a pivot point such that the device has a substantially disc shape when fully expanded and a substantially pie shape when partially expanded; and a lip defining an outer diameter of the device when fully expanded. The outer diameter of the device is equal to or greater than an inner diameter of the inner surface of the container.
US10899166B2 Digitally injected designs in powder surfaces
Building panels and a method to produce such panels including a solid decorative surface having a decorative wear layer including fibres, binders, colour substance, wear resistant particles and a digital ink print.
US10899164B1 Clipboard jacket
A cover having an opening, a border, a rain screen, and a pouch, and being comprised of a flexible material and a stretchable material, wherein the cover may be used in combination with a planar rigid insert, such as a clipboard. The cover may include a strap and a handle attached to the cover.
US10899163B2 Optical security device
The invention relates to an optical device comprising two patterned retarders and a reflective polarizer between the retarders. Information which is stored in the pattern of the retarders can be observed both in transmission and reflection. The device according to the invention can be used as high security element, for example for banknotes.
US10899162B2 Laminates, identification documents, and methods for verifying identification documents
A laminate includes: a first laminate member; a second laminate member; and a hidden print formed by printing invisible ink between the first laminate member and the second laminate member. The hidden print is configured to absorb electromagnetic radiation outside the visible range. When irradiated with electromagnetic radiation outside a visible range that has passed through at least one of the first laminate member and the second laminate member, the hidden print absorbs the electromagnetic radiation to thereby show a sign, and, when irradiated with visible light, the hidden print does not show the sign.
US10899158B2 Hinged repositionable business card
A business card comprises front and back sides and a flap permanently attached to the business card. The flap comprises front and back sides and an adhesive on at least a portion of the flap's back side. The adhesive is capable of removably and reusably adhering to objects. The flap is foldable with respect to the business card such that the flap can be placed in at least two configurations. In a first configuration, the adhesive adheres to a portion of the back side of the business card, so that the business card is non-adhesive and can be used like a convention business card. In a second configuration, the flap aligns at least approximately with the business card, thereby presenting the flap's adhesive to be able to adhere to another object such that the front side of the business card faces outward from said another object.
US10899155B2 Variable printed UV curable adhesive retail signs
An adhesive sign suited to use in retail applications includes a substrate layer. An adhesive layer is disposed on the substrate layer. The adhesive layer defines an exposed region for attachment to an associated structure. The adhesive layer is derived from a photo-curable inkjet composition. An ink layer is disposed on the substrate layer. The ink layer includes an image. The ink layer is derived from a photo-curable inkjet composition. The adhesive layer and ink layer can be formed in the same inkjet printing process and cured in a common photo-curing station. A stack of the adhesive signs can be assembled without interleaving a release liner between each pair of signs.
US10899153B2 Heat-sensitive recording material and diphenylsulfone
The content of compound(s) having a molecular weight of 650-670, typically a molecular weight of 660, as measured by mass spectrometry, is reduced to 0.5 mass % or less in a heat-sensitive recording material comprising 3,3′-diallyl-4,4′-dihydroxy diphenylsulfone, or in a diphenylsulfone or a color-developing agent. Provided is, thereby, a heat-sensitive recording material, a color-developing agent, or a diphenylsulfone which cause less background fogging under moisture and heat conditions and which has excellent preservation stability of a colored image.
US10899150B2 Liquid processing device
Each of a first pressing member and a second pressing member is rotatable about a predetermined axis so as to be capable of changing its posture between a first posture and a second posture inclined upward at its end from the first posture, and is disposed on the mounting part in a rockable manner in a direction pressing the head unit, so as to press the head unit in the first posture.
US10899146B2 Method of inkjet printing onto aligners
Provided herein are methods of obtaining good photocured-ink adhesion to low surface energy materials. The methods have greatly improved adhesion of photocured ink on low surface energy materials, including those that are subjected to high humidity or wet environments. The methods take into account the glass transition temperature (Tg) of the materials and the onset for the glass transition temperature, including ink applied to an exposed surface of the material at an elevated temperature that is close to the Tg of the material. The ink is allowed to sit briefly or soak, such as for more than 1 second, before the ink is cured. The ink may be photocured. Furthermore, the methods do not require solvents or surface treatment, including plasma or corona treatments, to obtain good ink adhesion.
US10899140B2 Automated device for adjusting print heads
A device for automatic adjustment of print heads in a printing machine is presented. The device can include at least one motor and a controller. The motor can drive at least one drive element for at least one retaining element, and drive at least one drive element for at least one adjustment element. The controller can control the at least one motor to: drive the at least one drive element to loosen the at least one retaining element, drive the at least one drive element to position the at least one adjustment element at a predetermined nominal value to position the adjustment element, and drive the at least one drive element to tighten the at least retaining element.
US10899139B2 Control device and storage medium
A control device for a printing execution unit including a printing head, a head drive unit, and a movement unit, wherein, in a case where a non-character object region is located at an upstream end of a partial region which is configured to be printed by a first partial printing: dots are formed in a first overlap region by both the first partial printing and a second partial printing, the first overlap region including the upstream end of the partial region, wherein, in a case where a character region is located at the upstream end of the partial region, dots are formed in a second overlap region by both the first partial printing and the second partial printing, the second overlap region including the upstream end of the partial region, and wherein a length of the second overlap region is shorter than a length of the first overlap region.
US10899135B2 Drop-on-demand printer with bottle ink supply and keyed bottle cap
An ink bottle is mounted in a DOD printer with the ink bottle acting as an ink supply reservoir that supplies ink to a DOD print head. A unique cap is provided that is configured to be affixed to an end of the ink bottle via threads or the like. The cap can be provided with one or more mechanical keying features used to limit mounting of the cap and the bottle assembly to a correct receiver in the DOD printer. The cap can also be provided with a valve controlled ink passage that allows ink to flow out of the bottle through the cap and a valve controlled vent passage that allows air to enter the bottle through the cap.
US10899133B2 System
A system includes: a housing; a cover that is supported by the housing to be movable between a covering position and an opened position; a tank; a reservoir; and a liquid discharging head that is disposed inside the housing and discharges liquid supplied from the tank, wherein the reservoir includes a liquid passage hole; the tank includes a passage tube that extends upward from the tank and is connectable to the liquid passage hole of the reservoir, the cover includes: a first wall that is positioned above the housing at the covering position, and a second wall that extends downward from an edge of the first wall, and when the cover is positioned at the covering position and the reservoir is connected to the tank, an upper end of the reservoir is positioned above a lower end of the second wall.
US10899127B2 Controlling printing fluid drop ejection
Examples are provided to methods to dynamically control the timing of a printing fluid drop ejection to deposit printing fluid on a print zone of a substrate. The examples may also provide measuring a height profile of a pre-print zone.
US10899124B2 To determine a quantity of a liquid in a chamber
A method to determine a quantity of a liquid in a container. In the method, a actuator is controlled to rotate a member in the container at a first speed. A measurement of electrical current drawn by the actuator at the first speed is received. A quantity of liquid in the container is determined through a look-up table and the measured electrical current.
US10899121B2 Digital print with water-based ink on panel surfaces
A water-based ink, produced by mixing pigments, binders and viscosity increasing substances such that they are specially adapted to provide and maintain a high quality print during heat and pressure, that no floating or bleeding of the ink drops should take place and that they are compatible with resins and materials used in the substrate such that no delamination or chemical reactions that affect design or surface properties in a negative way should take place. Additionally, a method to form a digital print with the water-based ink on a dense substrate including a polymer material or on surfaces that are heated and pressed after printing. The surface is, prior to the printing step, preferably heated in order to prevent floating of the water-based ink drops.
US10899113B2 Multilayer cast films with reduced blocking and methods of making same
Multilayer cast films with an ethylene/α-olefin copolymer core layer, and inner and outer layers containing low density polyethylene homopolymers, and multilayer cast films with an ethylene polymer core layer, and inner and outer layers containing ethylene/α-olefin copolymers, are described. These cast films have a reduced tendency to block, and are useful in various food packaging applications.
US10899107B2 Building membrane with porous pressure sensitive adhesive
A breathable multilayer spun bonded polypropylene membrane having a coated pressure sensitive adhesive capable of allowing air and moisture vapor to pass through it. The adhesive is formed of a copolymer comprising a backbone of n-butyl acrylate, 2-ethylhexyl acrylate, and vinyl acetate which is mixed with a surfactant and emulsified to produce bubbles which form pores when the copolymer is set with about 80% to about 90% of the pore sizes ranging from about 200 microns to about 300 microns and a pore density in the cured pressure sensitive adhesive ranging from about 4200 per inch2 to about 4600 per inch2, said pores being uniformly distributed to form a flow path through adhesive.
US10899106B1 Three-dimensional, knitted, multi-spectral electro-magnetic detection resistant, camouflaging textile
An easily handled, lightweight, three-dimensional camouflage material relying on an outer fabric layer and an inner fabric layer separated by an intermediate pile for effective multi-spectral, electromagnetic detection suppression in the visual, near infrared, thermal infrared, microwave, and radar wavebands is provided herein.
US10899104B2 Method for manufacturing a registered embossed decorative panel
A method for manufacturing a registered embossed decorative panel including providing a substrate having a printed design, applying a coating to the surface of the substrate, applying a release foil to the coating, curing the coating to maintaining the position of the release foil, printing a resin on the release foil, consolidating the composite under heat and pressure, and removing the release foil.
US10899100B2 Powder press and a feed housing having preferably a plurality of stamps which are movable for a transverse press
Powder press having preferably stamps which are movable for a transverse press in a feed housing. The stamps partially delimit a hollow chamber of a matrix in the feed housing and are able to be coupled to a press device by one connector piece each. An adjustable positioning device, which is formed from a wedge arrangement having a stop surface and placed crosswise to the moving direction of the stamp, is allocated to the respective stamp for determining the pressing position thereof. The wedge arrangement includes at least one wedge which is adjustable crosswise to the moving direction of the stamp and has the stop surface which contacts a stop surface at the stamp. Such a wedge arrangement can achieve very accurate pressing positions of the stamp, and extremely stable positioning of the stamp to be pressed with high pressure.
US10899096B2 Drum set for manufacturing a bead-apex for a tire and assembly comprising said drum set
Provided is a drum set for manufacturing a bead-apex for a tire and an assembly including the drum set, wherein the drum set has drum segments which form a drum, wherein the drum segments are radially movable, wherein the drum set is arranged to be movable between an operational position in which the drum set is supported on a base and a storage position in which the drum set is unsupported by the base. The drum set further includes a support member for supporting the drum segments of the drum set with respect to each other, wherein the support member is provided with guides for guiding the radial movements of the drum segments when the drum set is in the operational position, while the guides are arranged for retaining the drum segments of the drum set to the support member when the drum set is in the storage position.
US10899085B2 Method for producing a multi-component part of a vehicle
A method for producing a multi-component part (200) of a vehicle includes inserting an air-guiding device (10) having at least one contact portion (40) into a cavity (310) of a tool (300). The method then includes heating a composite part (100) having at least one mating contact portion (140) to a melting point of at least one material of the composite part (100), and heating the contact portion (40) of the air-guiding device (10) to a melting point of at least one material of the contact portion (40). The method further includes inserting the heated composite part (100) into the cavity (310) of the tool (300) and pressing the heated composite part (100) into a geometry of the part while simultaneously forming an integrally bonded connection between the mating contact portion (140) of the composite part (100) and the contact portion (40) of the air-guiding device (10).
US10899080B2 Method for producing shaped bodies
A generative process for the manufacture of three-dimensional mouldings is characterized by constructing the moulding stepwise by site-specific delivery of a structure-forming material in liquid form, where a second material is additionally delivered as a supportive material into regions which are intended to remain free from the structure-forming material, and is removed once the structure-forming material has been solidified. The supportive material exhibits low shrinkage upon cooling and is particularly stable in the cooled state and further exhibits low surface roughness.
US10899079B2 Optical shaping apparatus and method of producing shaped article
Provided is an optical shaping apparatus that includes a light source that outputs diffusion light or converging light as outgoing light, an optical function section that is disposed in an optical path of the outgoing light and modulates the optical path or a phase of the outgoing light, and a sensor that acquires positional data of an object surface. The optical shaping apparatus further includes a controller that controls operation of the optical function section on the basis of the positional data and coordinate data of a shaped article, to apply modulated light generated by the optical function section to the object surface.
US10899077B2 Techniques for build platform part release in additive fabrication and related systems and methods
According to some aspects, an additive fabrication device and a build platform suitable for use within an additive fabrication device are provided. The build platform may include a build surface on which material may be formed by the additive fabrication device when the build platform is installed within the additive fabrication device. According to some embodiments, the build platform may include a flexible build layer and at least one removal mechanism configured to be actuated to apply a force to the flexible build layer. Such actuation may cause the flexible build layer to deform, thereby enabling separation of material adhered to the build surface from the build platform. According to some embodiments, the build platform may comprise a restorative mechanism that acts to return the flexible build layer to a flat state so that subsequent additive fabrication may form material on a flat build surface.
US10899071B2 Systems and methods for improved 3D printing
A system for fabricating an object includes an extruder for one or more deposition materials. The extruder has at least one nozzle with a nozzle tip that includes an exit orifice and has a width that is equal to or larger than a width of the exit orifice. The system also includes a controller coupled with the extruder, the controller configured to apply a correction factor that has been calculated for a path of the nozzle based on a slope of a surface of an object to be fabricated. The correction factor for a positive slope is different from that for a negative slope. The extruder is configured to cause movement of the nozzle along the path to deposit material on the slope of the surface of the object, and the correction factor removes differences in thickness of the deposited material caused by the slope in relation to the path.
US10899070B2 Filament for material extrusion-type three-dimensional printers, wound body composed of said filament, cartridge containing said filament, and method for producing resin molded article using said filament
An object of the invention is to provide a filament for a material extrusion-type three-dimensional printer, which filament contains an aromatic polyester resin, and which overcomes the shortcomings of a filament for a material extrusion-type three-dimensional printer that is composed of an ABS resin. Provided is a filament for a material extrusion-type three-dimensional printer, the filament including an aromatic polyester resin containing 50 mol % or more of aromatic dicarboxylic acid units, and 3 mol % or more of isophthalic acid units, with respect to the total amount of dicarboxylic acid units. The aromatic polyester resin preferably has a melt flow rate (230° C., 2.16 kgf) of 7 g/10 min or more, and an intrinsic viscosity of 0.80 dL/g or less.
US10899069B2 Mechatronic movement system for three-dimensional printer using helical racks and pinions
Disclosed is a mechatronic movement system for three-dimensional printing for a rapid-prototyping machine, such as a 3D printer, of the type provided with at least one microprocessor electronic management board, in which the movement of the printing way of the 3D printer along the axes X and Y of the horizontal plane is obtained exclusively with geared kinematic chains.
US10899067B2 Multi-layer stamp
A stamp for micro-transfer printing includes a support having a support stiffness and a support coefficient of thermal expansion (CTE). A pedestal layer is formed on the support, the pedestal layer having a pedestal layer stiffness that is less than the support stiffness and a pedestal layer coefficient of thermal expansion (CTE) that is different from the support coefficient of thermal expansion (CTE). A stamp layer is formed on the pedestal layer, the stamp layer having a body and one or more protrusions extending from the body in a direction away from the pedestal layer. The stamp layer has a stamp layer stiffness that is less than the support stiffness and a stamp layer coefficient of thermal expansion that is different from the support coefficient of thermal expansion.
US10899063B2 Blow molded part including compression molded element
In one example, a structure is provided that includes a plastic body having a unitary, single-piece construction. The plastic body further includes a substantially hollow interior, and a parting line that extends around a portion of the perimeter of the structure. The structure also includes a solid compression molded element that is integral with the plastic body. The solid compression molded element is configured and arranged such that the parting line is not connected to the solid compression molded element.
US10899061B2 Cooling and vacuum tank
A calibration and cooling tank of an extrusion line, which connects to an extrusion tool, wherein a vacuum can be applied to the calibration and cooling tank for calibrating the plastic melt emerging from the extrusion tool, wherein the calibration and cooling tank extends along an extrusion axis. The calibration and cooling tank is modularly structured, wherein at least one module forms a calibration and cooling section and the module has a connection region on both sides to which an additional module can be attached. The connection region includes a flange that extends from the base element of the calibration and cooling tank to the outside.
US10899055B2 Valve pin and nozzle configuration and method of control
An injection molding apparatus comprising: a manifold, a nozzle, A distal tip of the nozzle being comprised of a highly heat conductive insert and an insulation cap that is substantially less heat conductive than the insert, the downstream end portion of the insulation cap being disposed between the gate and the downstream end portion of the highly heat conductive insert forming a fluid seal around the gate, a valve pin, wherein when the valve pin is in a gate closed position, an axially interior surface of a fluid exit aperture of the insulation cap surrounds a gap enabling circumferential surface of the valve pin forming a spatial gap immediately upstream of the gate between the interior surface of the fluid exit aperture of the insulation cap and the gap enabling circumferential surface of the valve pin.
US10899048B2 Method for manufacturing gloves
A method for producing a glove includes a step of forming a dip-molded layer by dip-molding a latex composition containing a latex of a carboxyl group-containing conjugated diene rubber (A) that does not have an isoprene-derived monomer unit, and a metal compound (B) including a divalent or higher metal, and a step of irradiating the dip-molded layer with radiation.
US10899046B2 Composite member
A composite member is provided with a bonding member made of a fiber-reinforced resin and a bracket in which the bracket is bonded to the bonding member via a resin. The bracket has a through-hole. The bonding member has a front surface side fiber-reinforced resin sheet and a rear-surface-side fiber-reinforced resin sheet. The front surface side fiber-reinforced resin sheet, the rear surface side fiber-reinforced resin sheet and the bracket are integrally bonded to each other by the resin in a state in which the front surface side fiber-reinforced resin sheet is inserted into the through-hole of the bracket to thereby enhance the bonding strength between the bonding member to the bracket.
US10899042B2 Pyrolysis system and method of recovering carbon fibres from carbon-fibre-containing plastics
The invention relates to a pyrolysis plant and a process for recovering (recycling) carbon fibers from carbon fiber-containing plastics, in particular from carbon fiber-reinforced plastics (CFPs or CFP materials), preferably from carbon fiber-containing and/or carbon fiber-reinforced composites (composite materials).
US10899040B2 Continuous twin-screw mixer and mixing method
A continuous mixer includes a barrel with a hollow interior, and a pair of mixing rotors housed in the barrel and that rotate in mutually different directions, each mixing rotor including a mixing portion with plural mixing flights formed about an axial center of the mixing rotor and projecting radially outward. The mixing rotors have a center distance therebetween smaller than a rotation outer diameter of each of the respective mixing flights. An inter-rotor clearance, which is the smallest clearance between the mixing portions at each rotation phase of the mixing rotors in a cross section perpendicular to axial directions of the both mixing rotors, has a dimension allowing an extensional flow to be generated in a material passing through the inter-rotor clearance. The continuous mixer can reliably and efficiently mix a material having a large viscosity difference between a dispersed phase and a matrix phase.
US10899037B2 Connecting rod ultrasonic-assisted splitting machining method and machining device thereof
Connecting rod ultrasonic-assisted splitting machining method and a machining device thereof, relating to the field of machining of a connecting rod. The machining device comprises a rack, a fixing block, a sliding block, a sliding block base, a vertical locking oil cylinder, a wedge-shaped pull rod, an adjusting block body, etc. By means of the method and the device thereof, the range of the material used for splitting the connecting rod is enlarged, the splitting force required during the splitting of the connecting rod, deformation of fracture surfaces, residues generated during the splitting process, out-of-roundness of big end holes of the connecting rod, and other situations are reduced, and the engaging accuracy of the connecting rod and the joint face of a connecting rod cover and the assembly quality of the connecting rod are improved.
US10899034B2 Method and machine for cutting logs of wound web material
The cutting machine for cutting logs of web material, includes a cutting head arranged along the feeding path of the logs. The cutting head includes a coupling for a disc-shaped cutting blade and is designed to impart the disc-shaped cutting blade a rotary motion around the axis thereof and a cyclic movement to cut the logs into single rolls, and to allow the logs to move forward along the feeding path. The machine also includes a store unit for disc-shaped cutting blades associated with the cutting head. A handling member is provided to remove a worn disc-shaped cutting blade from the cutting head and replace the worn disc-shaped cutting blade with a new disc-shaped cutting blade taken from the store unit.
US10899033B2 Tool and method for separating and picking cut pieces of flexible materials
The disclosure relates to a method and apparatus for uncut material detection while lifting from an automated cutting table select pieces of thin, flexible material. The apparatus comprises a structured energy source and a structured energy sensor. The structured energy can be used to detect undesired lifting of a peripheral portion of the flexible material resulting from the presence of uncut material.
US10899028B2 Unitary razor cartridge and method for assembling the same
A razor cartridge and a method for assembling a razor cartridge are disclosed. A razor cartridge includes: a blade housing including a seat configured to receive at least one blade; a pair of side caps respectively disposed at opposite ends of the blade housing, wherein each side cap is configured to be engaged with a corresponding end of the blade housing; and a plurality of bridges, wherein one or more bridges are disposed at each end of the blade housing and configured to provide a moveable connection between the side cap and the corresponding end of the blade housing, wherein the blade housing, the pair of side caps, and the one or more bridges are integrally formed, and wherein each side cap is configured to secure the at least one blade to the blade housing when the side cap is engaged with the corresponding end of the blade housing.
US10899026B2 Utility knife
A knife having a housing (11) and a blade support (18) for holding a blade (19), the blade support being movable between a retracted position in which the blade support (18) is moved by a reset device (22) against a stop of the housing (11), and a fully advanced position, the blade support having a base (23) and a blade cover (24) movable between a closed position and an open position relative to the base (23), and in the closed position, the base (23) and the blade cover (24) firmly secure the blade (19) in a blade seat (41) between the base (23) and the blade cover (24) and in the open position, the base (23) and the blade cover (24) are so oriented relative to each other that a blade can be changed.
US10899025B2 Food slotting device and method
A FOOD SLOTTING DEVICE includes a holding unit, an assembly of slicing blades arranged in a perpendicular fashion, and an affixed cover piece, for creating an elongated cross-hatch pattern of perpendicular slots by partially slicing into one or more surface areas on the body of a food product, generally of an elongated nature, such as a hot dog, wiener, frankfurter, sausage or the like through the directional application of force, such as the METHOD of carrying out such partial slicing denotes. Thereafter the partially sliced food product is easily removed from the slicing blades assembly of the FOOD SLOTTING DEVICE prior to cooking, grilling, or further processing. The slots prevent bursting by permitting gases generated by the cooking process to escape, allowing penetration of the heat to the center of the food product providing quicker cooking thereof, thereby providing for a more palatable and pleasant looking food product.
US10899023B2 Failure diagnosis device and failure diagnosis method
A failure diagnosis device applicable to a mechanical device provided with motors independent of One another as sources to drive motion axes, respectively, and configured to acquire a moving position of each motion axis and a disturbance torque value applied to the motion axis every predetermined period, and to diagnose a failure of the mechanical device, includes a failure diagnosis unit configured to diagnose the motion axis as a failure when the disturbance torque value is larger than a predetermined failure determination threshold, and a re-determination unit configured to conduct re-determination of the failure on the motion axis, which is diagnosed as the failure by the failure diagnosis unit, based on a previous maintenance record and a previous inspection result.
US10899022B2 Sensor device having a force detection element sandwiched by two sensor signal processing circuits
A sensor device includes a base body including a recess, a lid body configured to close an opening of the recess, a force detection element disposed in the recess and including a first element that outputs a first signal according to an external force in a first axis and a second element that stacks on the first element and outputs a second signal according to an external force in a second axis; a first circuit disposed in the recess and configured to process the first signal, and a second circuit disposed in the recess and configured to process the second signal.
US10899021B2 Wheeled cart with vibration reduction device, and related systems and methods
A surgical cart assembly may comprise a base portion; a plurality of wheels coupled to the base portion; a column extending vertically from the base portion; a manipulator arm coupled to an end portion of the column; a stabilization device coupled to the base portion, the stabilization device moveable between a retracted position and a deployed position; an actuation device to cause movement of the stabilization device between the retracted position and the deployed position; and a biasing element coupled to the stabilization device, the biasing element exerting a biasing force to bias the stabilization device toward the retracted position. The stabilization device may comprise a stabilization surface, the stabilization surface contacting the ground surface on which the surgical cart assembly is supported in the deployed position of the stabilization device, and the stabilization surface spaced from the ground surface in the retracted position of the stabilization device.
US10899018B2 Human-collaborative robot
A human-collaborative robot, by which the robot is unlikely to be accidentally operated despite the intention of the human, even if a relatively simple action pattern is determined as a command to the robot. When an external force by a human is applied to the robot, the force is detected by a force sensor. The robot is configured to be stopped when the detected external force exceeds a predetermined threshold. In order to restart the stopped motion of the robot, the human purposely applies the external force to the robot. When a judging section judges that the external force is applied to a specified portion the robot based on a predetermined action pattern, a commanding section commands the robot so that the robot performs a motion which is previously associated with the pattern.
US10899016B2 Robot and robot control system
An example system includes a vehicle, a robot, and a controller. The vehicle may include an accelerator operator and a steering operator. The robot may include as accelerator actuator configured to operate the accelerator operator, and a steering actuator configured to operate-the steering operator. The controller is configured to: in response to an accelerator command, send a first signal to the accelerator actuator to operate the accelerator operator of the vehicle, and in response to a steering command, send a second, signal to the steering actuator to steer the vehicle.
US10899014B2 Multiple lens-based smart mechanical arm and positioning and assembly method thereof
A multiple lens-based smart mechanical arm, wherein it comprises a multi joint multi-functional mechanical arm, a CCD camera for collecting PCB board images to be assembled, a bio-contact device, and a computer; the CCD camera is mounted on the multi joint multi-functional mechanical arm, the bio-contact device is mounted on the fingertip of the multi joint multi-functional mechanical arm, and the CCD camera, and the bio-contact device and the multi joint multi-functional mechanical arm are connected to the computer. The invention adds a biological tactile device on the basis of the binocular positioning to accurately locate the assembly target area and improve the accuracy of the assembly of the irregular parts. The conversion relationship between the pressure and electric output of the sensitive material in the bio-contact device and the mathematical model of pressure and position is applied. The present invention realizes high-precision and real-time assembly of irregular parts and improves the production efficiency of the electronic assembly industry.
US10899013B2 Eccentricity error correction method for angle detector and robot system
In an eccentricity error correction method for an angle detector, an output shaft angle is determined in at least three measurement positions. A difference between an arm angle value at each measurement position and the output shaft angle detected at each measurement position is determined as an eccentricity error. An error curve indicates a relationship between the arm angle value and the eccentricity error, and is determined as a function of the arm angle value by approximating the eccentricity error at each measurement position with a sine wave of which a single cycle is a single rotation of the arm. A correction formula that associates the output shaft angle and the arm angle value is determined using the error curve. A correction value corresponds to the detected output shaft angle, and is determined based on the correction formula and correcting the eccentricity error when the arm is rotated.
US10899012B2 Coordinated robot to robot component assembly
A method of assembling a secondary component to a primary component comprises grasping a primary component with a first end-of-arm tool, wherein the first end-of-arm tool is attached to a first robot arm and grasping a secondary component with a second end-of-arm tool, wherein the second end-of-arm tool is attached to a second robot arm. Moving the primary component to an interfacing position, wherein interfacing surfaces on the primary component are presented at a proper position and orientation for the secondary component to be attached thereto. Moving the second end-of-arm tool to bring the secondary component into engagement with the interface surfaces of the primary component, and forming a joint between the primary component and the secondary component with a joining tool attached to a joining robot arm.
US10899007B2 Ensuring safe operation of industrial machinery
Systems and methods monitor a workspace for safety purposes using sensors distributed about the workspace. The sensors are registered with respect to each other, and this registration is monitored over time. Occluded space as well as occupied space is identified, and this mapping is frequently updated.
US10898996B2 Combustion-powered placing tool and method for operating such a placing tool
A combustion-powered placing tool for driving fastening elements into a subsurface comprises a main combustion chamber for a compressible fuel, a driving piston, which in a starting position is retracted, and which can be driven from the main combustion chamber in the placing direction via expandable gases, a prechamber to which an ignition device is assigned, and in which a pressure acting upon the main combustion chamber can be build up prior to ignition of a fuel-air mixture in the main combustion chamber, wherein an additional ignition device is assigned to the main combustion chamber. In order to improve the effectiveness and/or the functionality during driving-in of a fastener, the placing tool comprises a selector device, allowing a selection between a reduced energy operation having an ignition in the main combustion chamber and a high-energy operation having an ignition in the prechamber.
US10898995B2 Powered fastener driving tool having fuel/gas mixture compressed ignition
Various embodiments provide a powered fastener driving tool including a spring/gas chamber configured to contain pressurized gas that causes a piston to compress a fuel/gas mixture, the mixture combusted to provide necessary levels of power for driving fasteners while using less fuel. One embodiment includes: a housing; a spring/gas chamber in the housing configured to contain pressurized gas; a dual compression/combustion chamber in the housing configured to contain a fuel/gas mixture; a gas communication channel in the housing fluidly connecting the spring/gas chamber and the dual compression/combustion chamber; a movable piston in the housing such that pressurized gas in the spring/gas chamber causes the piston to move in the housing to compress the fuel/gas mixture in the dual compression/combustion chamber; and a driving blade connected to the piston such that combustion of the compressed fuel/gas mixture causes the piston to move in the housing to cause the driving blade to drive a fastener.
US10898986B2 Chattering correction for accurate sensor position determination on wafer
A method of controlling polishing includes sweeping a sensor of an in-situ monitoring system across a substrate as a layer of the substrate undergoes polishing, generating from the in-situ monitoring system a sequence of signal values that depend on a thickness of the layer, detecting from the sequence of signal values, a time that the sensor traverses a leading edge of the substrate or a retaining ring and a time that the sensor traverses a trailing edge of the substrate or retaining ring; and for each signal value of at least some of the sequence of signal values, determining a position on the substrate for the signal value based on the time that the sensor traverses the leading edge and the time that the sensor traverses a trailing edge.
US10898977B2 Adding cutting stations to bending systems
A system for generating rules inserted into at least one pattern board including: a controller configured to generate at least one shape diagram, the controller also configured to determine number and measurement of crease rules to be generated based on the at least one shape diagram; a cutting station configured to receive and cut a first crease rule into the number and measurement of the crease rules; and a sorter configured to receive the crease rules from the cutting station and sort the crease rules according to the measurement of the crease rules, wherein the sorted crease rules are inserted into each of the at least one pattern board along with a cutting rule shaped by each of at least one bender.
US10898976B2 Method of manufacturing a box header for heat exchanger
A method of manufacturing a box header for an air-cooled heat exchanger. The method includes the steps of boring at least one hole into at least one end of an elongated slab of metal. Material from the slab is milled out adjacent to the at least one hole to form an elongated internal chamber in the slab having at least one open end. An inlet nozzle opening is machined into the elongated chamber and an outlet nozzle opening is machined into the elongated chamber. A plurality of tube holes and a plurality of plug holes are drilled and tapped in the elongated slab into the internal chamber. An end block is welded to the at least one open end in order to form a closed internal chamber.
US10898972B2 Laser crystallizing apparatus
A laser crystallizing apparatus includes a stage configured to receive a substrate, the stage including a plurality of groove lines each having a predetermined depth and width, and a plurality of control holes, each arranged in a respective groove line. Each control hole is provided with a negative pressure to hold the substrate to a surface of the stage or a positive pressure to release the substrate from the surface of the stage.
US10898971B2 Three-dimensional deposition device and three-dimensional deposition method
A three-dimensional deposition device and a three-dimensional deposition method used to highly accurately manufacture a three-dimensional object are provided. A three-dimensional deposition device for forming a three-dimensional shape by depositing a formed layer on a base unit includes: a powder supply unit which supplies a powder material; a light irradiation unit which irradiates the powder material with a light beam so that at least a part of the powder material irradiated with the light beam is sintered or melted and solidified to form the formed layer; a heating unit which selectively heats an area having passed through a position irradiated with the light beam in the base unit or the formed layer or an area not having passed through the position irradiated with the light beam; and a control device which controls operations of the powder supply unit, the light irradiation unit, and the heating unit.
US10898968B2 Scatter reduction in additive manufacturing
Systems and methods for reducing charged powder particle scattering in powder-bed fusion (PBF) systems are provided. A PBF apparatus can include a structure that supports a layer of powder material having a plurality of particles of powder. For example, the structure can be a build plate, a build floor, a build piece, etc. The apparatus can also include an energy beam source that generates an energy beam and a deflector that applies the energy beam to fuse an area of the powder material in the layer. The energy beam can electrically charge the particles of powder. The apparatus can also include an electrical system that generates an electrical force between the structure and the charged particles of powder. For example, the electrical system can include a voltage source that applies a first voltage to the structure.
US10898964B2 Method and apparatus for providing welding type power
A welding-type power supply includes a controller, a preregulator, a preregulator bus, and an output converter. The controller has a preregulator control output and an output converter control output. The preregulator receives a range of inputs voltages as a power input, and receives the preregulator control output as a control input, and provides a preregulator power output signal. The preregulator includes a plurality of stacked boost circuits. The preregulator bus receives the preregulator output signal. The output converter receives the preregulator bus as a power signal and receives the output converter control output as a control input. The output converter provides a welding type power output, and includes at least one stacked inverter circuit.
US10898960B2 Miter saw
A miter saw has a base assembly, a table rotatably disposed on the base assembly, a support section rotatably connected to the table, a guide bar fixedly attached to and extending forwardly from the support section, and a saw assembly sliding along the guide bar. The saw assembly is pivotable downwardly for cutting a workpiece disposed on the table. A handle is disposed adjacent to a forward end of the guide bar. The handle is movable between a first position for fixing a rotational position of the support section relative to the table, and a second position for allowing rotational movement of the support section relative to the table.
US10898959B2 Means for preventing tools from being pulled out from tool holders with a tool holding fixture
The invention relates to a tool holder with a tool holding fixture, in particular a clamping chuck such as a contracting chuck, a draw-in collect chuck, a hydraulic expanding chuck and a high-precision chuck, and a shank of a tool, in particular a rotary tool, accommodated in it, wherein the tool holder contains a means for preventing the tool from being pulled out, locking it against axial displacement. This pull-out preventing unit comprises at least one locking element and at least one locking groove, which corresponds to the said locking element, receives it and interacts with it in a positively locking manner. In this case, both the locking element and the locking groove are formed at least partly in the manner of a ball head. Preferably, the tool has the locking grooves. On account of preferably spirally arranged locking grooves along the cylindrical shank of rotary tools, the direction of pitch of which grooves corresponds to the direction of the grooves of the tool, axial locking of the tool is obtained, so that the tool cannot be axially displaced from the tool holder during operation. In addition, force-exerting elements are arranged, with the effect of making the tool lie against the pull-out preventer without play after shrink-fitting.
US10898957B2 Production apparatus and production method for fine particles
A production apparatus and method for fine particles are capable of increasing a production amount and producing fine particles at low cost by efficiently inputting a large amount of material to plasma. The production apparatus includes a material supply device, which includes a plurality of material supply ports that supply a material gas containing material particles and are arranged below a plurality of electrodes in a vertical direction inside a vacuum chamber. The material supply device further includes a first gas supply port that supplies a first shield gas arranged in an inner periphery of the plural material supply ports and plural second gas supply ports that supply a second shield gas arranged in an outer periphery of the plural material supply ports.
US10898950B2 Dust core, electromagnetic component and method for manufacturing dust core
A dust core includes: a plurality of soft magnetic particles composed of an iron-based material; an insulating layer including a coating layer that is composed mainly of a phosphate and covers the surface of the soft magnetic particles; and insulating pieces containing a constituent material of the insulating layer, each of the insulating pieces being surrounded by at least three mutually adjacent ones of the soft magnetic particles while separated from the insulating layer.
US10898948B2 Method of manufacturing metal castings
A method of manufacturing an aluminum alloy cylinder head includes providing a precision sand core and mold assembly, a liquid aluminum alloy delivery system, and a mold manipulator system. The precision sand core and mold assembly is disposed in the mold manipulator system and the liquid aluminum alloy delivery system includes an in-furnace ultrasonic actuator and a launder tube having at least an ultrasonic actuator. The liquid aluminum alloy delivery system is sealed to the precision sand core and mold assembly and provides liquid aluminum alloy into a gating system of the precision sand core and mold assembly. The precision sand core and mold assembly is rotated approximately 180°. The precision sand core and mold assembly is vibrated.
US10898943B2 Self-piercing rivet device and method of operating a self-piercing rivet device to inhibit incorrect die usage
A method of operating a riveting tool includes mounting a die in an installed position, determining an actual stroke distance of the riveting tool, comparing the actual stroke distance to a predetermined stroke distance that is based on a desired rivet location, and operating or not operating the riveting tool to install a rivet into workpieces, based on the result of the comparison.
US10898938B2 Method for manufacturing panel-like formed article
This method for manufacturing a panel-like formed article has preparing a blank material made of a metal sheet having a tensile strength of 390 MPa or more and 980 MPa or less; and press-forming the blank material in a cold manner using a pressing apparatus to form the blank material into the panel-like formed article, in the press-forming, a blank holder, a first punch, and a second punch are relatively moved with respect to a die, thereby pressing the first punch and the second punch to the blank material, and pressing of the second punch to the blank material is completed before pressing of the first punch to the blank material.
US10898937B2 Application of the 3D cameras to the profile bending process on the bending machine with three and four rollers
A bending machine has an automated profile bending process for providing controlled management, regulation of the controlled management, correction of the automated profile bending process, and application of 3D cameras to the bending machine. The bending machine includes a first camera fixed to a first holder and a second camera fixed to a second holder. The bending machine further includes rollers for applying the holders to the bending machine to provide a three-dimensional view of a portion of the bending process. The bending machine even further includes a computer for controlling the bending process, and the bending process includes a profile defined dimensionally and in space relative to the bending machine.
US10898936B2 Plastic working method for magnesium alloy
A plastic working method for a magnesium alloy, wherein the magnesium alloy is subjected to a friction stir process whereby a probe at the tip portion of a tool rotating around an axial line is press-fitted to the surface of the magnesium alloy, the magnesium alloy is heated and softened by friction between the magnesium alloy and the rotating tool, and the tool is moved parallel to the surface of the magnesium alloy while the tool is rotated with the probe in the press-fitted state. When the length in a first direction of the region of the magnesium alloy being plastically worked is A, and the amount of shrinkage of the magnesium alloy in the first direction due to the friction stir process is α, A+α is set as the length in the first direction of the region subjected to the friction stir process.
US10898933B2 Oleophobic glass articles
Described herein are glass substrates having oleophobic surfaces that are substantially free of features that form a reentrant geometry. The surfaces can include a plurality of gas-trapping features, extending from the surface to a depth below the surface, that are substantially isolated from each other. The gas-trapping features are capable of trapping gas below any droplets that are contacted with the surface so as to prevent wetting of the surface by the droplets.
US10898932B2 Method and apparatus for cleaning a substrate and computer program product
A method and an apparatus for cleaning a substrate having at least one surface having a residue to be removed thereon is described. The method comprises: scanning at least an area of the surface having the residue thereon with laser light to thereby heat the surface and the residue; controlling the heating so that a part of the residue first liquefies such that the liquefied part of the residue starts flowing towards the solid part of the residue, thereby forming a meniscus with the solid part of the residue and accumulating in part on top of the solid part, the thus generated thicker layer of residue absorbing further heat to be decomposed or vaporized.
US10898929B2 Bellows connecting adjacent carriages, in particular carriages of a material handling sorter
A bellows (1) connecting adjacent carriages (3), in particular carriages of a material handling sorter (2) along a predetermined path (P), being robust and reliable, comprises opposite heads (4a, 4b) each being associated with a carriage (3) and a pleated structure (5) with a preset number of substantially M-shaped elements (6) being provided with a plurality of vertices (7), as well as a bearing structure (8) formed by a base structure (8) and by a frame (8″) slidingly abutting on the base structure (8) such base structure (8′) and such frame (8″) being rigid and cooperating with each other, being placed between adjacent carriages inside the bellows (1).
US10898925B2 Ultrasound transducer assembly and method for manufacturing an ultrasound transducer assembly
The present invention relates to an ultrasound transducer assembly, in particular for intravascular ultrasound systems. The ultrasound transducer assembly comprises at least one silicon substrate element including an ultrasound transducer element for emitting and receiving ultrasound waves and including electrical connectors for electrically connecting the transducer element. The substrate element has a top surface, a bottom surface and a side surface connecting the top surface and the bottom surface. An isolation layer forms the side surface for electrically isolating the substrate element.
US10898921B2 Coating apparatus having a well-definied gap for controlling thickness of a layer of rheological material applied to a flexible film
Systems and methods for dispensing liquid materials as may be used in applications for coating flexible films and the like. Such a film may be coated by dispensing a rheological material onto its surface while drawing the film through a gap between a pair of rollers. The gap defines the thickness of a layer of the material applied to the film and is maintained at a desired width by microwires positioned through the gap. Another film across the gap from that to which the rheological material is applied aids in the coating of the layer and a contact area of the second film may be adjusted relative to the gap, e.g., when changing materials or when the coating film becomes abraded or deformed.
US10898918B2 Holster for spray gun
A holster for a spray gun is provided. The holster is configured to hold a spray gun in place when not in use. The holster has a reservoir body that defines an open-topped chamber. A fluid may be held inside the chamber, and a nozzle of the spray gun held by the holster may submerge in this fluid. The nozzle being submerged in the fluid of the holster can prevent hardening, thickening or drying of any material left over on or in the spray gun nozzle after use.
US10898914B2 Methods and systems for creating aerosols
A method of creating aerosols includes drawing a fluid from a fluid source through a first nip, the first nip defined between a first roller and an inner surface of a ring, the first nip having an upstream side and a downstream side, drawing the fluid from the fluid source through a second nip, the second nip defined between a second roller and the inner surface of the ring, the second roller positioned adjacent to and spaced apart from the first roller in a circular configuration, the second nip having an upstream side and a downstream side, stretching the fluid between diverging surfaces of the first roller and the inner surface of the ring on the downstream side of the first nip to form a first fluid filament, stretching the fluid between diverging surface of the second roller and the inner surface of the ring on the downstream side of the second nip to form a second fluid filament, causing the first fluid filament to break into a plurality of first droplets, and causing the second fluid filament to break into a plurality of second droplets.
US10898911B2 Device for dispensing a mixture, preferably a foam, and system using said device
The invention concerns a device (10) for dispensing a mixture (S) constituted by a first fluid (F1) and a second fluid (F2), suited to be applied to a container (C). The device comprises: an outlet duct (20) for the mixture (S); a reception and/or transit chamber (43); means (50, 60) for generating the mixture (S); first valve means comprising a first movable element (32); second valve means comprising a second movable element (32); third valve means comprising a third movable element (31a, 31b). Two among the first movable element (32), the second movable element (32) and the third movable element (31a, 31b) belong to a single valve element (30; 130). The invention concerns also a system for dispensing a mixture (S) constituted by a first fluid (F1) and a second fluid (F2) comprising a container (C) and a device (10) as described above.
US10898910B2 Generator usable in a potentially explosive atmosphere and assembly comprising an electrostatic sprayer and such a generator
A generator usable in an explosive atmosphere zone, and having a power greater than or equal to 8 Watts, preferably greater than 10 Watts, and an assembly including an electrostatic sprayer for a coating product and the generator.
US10898906B2 Centrifuge and control method therefor, computer program carrying out the method
A control method for a centrifuge is performed by a motor drive unit to drive a motor of the centrifuge using pulses from an angle sensor. The method has a start phase, a regulated acceleration phase, a holding phase, a regulated deceleration phase, a regulated gentle deceleration phase, and a position adjustment phase.
US10898902B2 Production line for recycling and processing waste materials of steel rolling
A production line for recycling and processing waste materials of steel rolling, the production line including: an electromagnetic hoisting equipment; a conveying platform; a clamping-and-feeding device; a segmentation shear; a swing conveyor device; a pushing device; a rolling-type shearing machine; a chain-type conveyor track; a material guiding device; two shredding-type shearing machines; and a scrap collection device. The electromagnetic hoisting equipment is connected to the conveying platform, and is configured to hoist waste materials of steel rolling to the conveying platform; the conveying platform is connected to the clamping-and-feeding device, and is configured to convey the waste materials to the clamping-and-feeding device; the segmentation shear cooperates with the clamping-and-feeding device and is configured to segment the waste materials of steel rolling into steel plates; the pushing device is configured to push the steel plates to the rolling-type shearing machine.
US10898899B2 Method and device for separating immiscible liquids to effectively isolate at least one of the liquids
A phase-separation device and method of use is provided for separating immiscible liquids. The phase-separation device has a porous membrane with a filter surface having a non-planar contour that forms a receiving cavity to receive a liquid mixture. The filter surface is configured to impede flow of a polar liquid into the porous membrane and permit flow of a non-polar liquid into the porous membrane.
US10898898B2 Multi-stage target cell enrichment using a microfluidic device
A microfluidic device and multi-stage target cell enrichment using the microfluidic device are disclosed herewith.
US10898894B2 Microfluidic diagnostic assembly
Improved diagnostic assemblies are provided. More particularly, the present disclosure provides improved and highly advantageous chip based diagnostic assemblies configured to detect human diseases (e.g., cancer) and/or pathogens, and related methods of use. In exemplary embodiments, the present disclosure provides for consumable micro- or nano-fluidic chip based diagnostic assemblies having visual biosensors, with the diagnostic assemblies using continuous flow-based micro- or nano-fluidic channels and antibody-based immuno-complex designs. In certain embodiments, the diagnostic assembly includes a self-sustainable and operable chip (e.g., thumb-sized chip) that is configured to be deployed as a single use consumable with a direct all-or-none readout as an output to satisfy a point of screening method to screen a population.
US10898890B2 Photocatalytic coating and method of making same
Described herein are methods for coating a substrate with a photocatalytic compound, and photocatalytic elements prepared by these methods.
US10898889B2 SCR catalyst and exhaust gas cleaning system
The present invention relates to a SCR catalyst comprising a carrier substrate of the length L, which is a flow-through substrate, and a coating A which comprises a small pore zeolite, copper and palladium.
US10898886B2 Hydrocarbon and nitrogen oxides catalyst trap
A hydrocarbon and NOx catalyst trap includes a three-way catalyst, and a zeolite layer adjacent to the three-way catalyst and including alumina and silica arranged to form a repeating skeletal frame that defines cavities including active metal active sites for hydrocarbon and NOx trapping such that individual atoms of the active metal are bound to the frame within the cavities via oxygen atoms.
US10898885B2 Nano-sized zeolite supported catalysts and methods for their production
According to one or more embodiments described, a zeolite supported catalyst may be synthesized by a process that includes combining a colloidal mixture with a metal oxide support material to form a support precursor material, processing the support precursor material to form a support material, and impregnating the support material with one or more metals to form the zeolite supported catalyst. The colloidal mixture may include nano-sized zeolite crystals, and the nano-sized zeolite crystals may have an average size of less than 100 nm.
US10898884B2 Zeolites, the production thereof, and their uses for upgrading heavy oils
According to one or more embodiments, a nano-sized, mesoporous zeolite particle may include a microporous framework comprising a plurality of micropores having diameters of less than or equal to 2 nm and a BEA framework type. The nano-sized, mesoporous zeolite particle may also include a plurality of mesopores having diameters of greater than 2 nm and less than or equal to 50 nm. The zeolite particles may be integrated into hydrocracking catalysts and utilized for the cracking of heavy oils in a pretreatment process.
US10898882B2 Surface-modified boron nitride nanostructure and method for producing same
The boron nitride nanostructure according to an embodiment of the present invention forms defects through surface modification and incorporates the metallic nanoparticles on the surface defects.
US10898881B2 Catalyst for metal mercury oxidation reactions and nitrogen oxide reduction reactions, and exhaust gas purification method
A catalyst for oxidation reaction of metallic mercury and reduction reaction of nitrogen oxide, comprising an oxide of titanium, an oxide of molybdenum, an oxide of vanadium, an oxide of phosphorus and gypsum is obtained by kneading titanium dioxide, ammonium molybdate, ammonium metavanadate, phosphoric acid, gypsum dihydrate and water using a kneader to obtain a paste, applying the paste to a metal lath substrate, and then drying and calcining the resultant.
US10898875B2 Dielectric barrier discharge reactor for catalytic nonthermal plasma production of hydrogen from methane
A dielectric barrier discharge reactor for catalytic nonthermal plasma production of hydrogen from methane. The dielectric barrier discharge reactor includes two end pieces connected by a dielectric tube, two steam generators, two catalyst cages, two perforated tube center electrodes, a center electrode rod, a grounding electrode. In one aspect, the end pieces and the dielectric tube are fabricated from ceramic and fused quartz respectively. In another aspect, the dielectric barrier discharge reactor further includes catalyst cages. In yet another aspect, the catalyst cages contain catalysts in form of pellets. In an alternate aspect, the dielectric barrier discharge reactor acts to cause a reaction between incoming reactant gases. The reaction is achieved under a plasma which is generated between the perforated tubular center electrode and the ground electrode. In yet another alternate aspect, the dielectric barrier discharge reactor is used at home to generate hydrogen from methane.
US10898869B2 Low holdup volume mixing chamber
A compact interaction chamber is used to cause high shear, impact forces, and cavitation to reduce particle size and mix fluids while reducing waste and holdup volume. A first housing made of stainless steel holds an inlet mixing chamber element and an outlet mixing chamber element in a female bore using thermal expansion. The inlet and outlet mixing chamber elements are manufactured so that the diameter of the cooled female bore is slightly smaller than the diameter of the mixing chamber elements. The first housing is heated, expanding the diameter of the female bore enough to allow the inlet and outlet mixing chamber elements to be inserted. After the mixing chamber elements are inserted and aligned within the female bore, the first housing is allowed to cool. Once cooled, the female bore contracts and applies sufficient hoop stress to securely hold the mixing chamber elements during high shear force mixing.
US10898868B2 Portable bubble water bottle
A portable bubble water bottle of the present application includes a first space, a second space, an one-way gas valve and a gas cylinder. The second space is located in the first space along the first projection direction. The one-way gas valve connects the first space with the second space. The gas cylinder is located in the second space, and has a gas outlet connected to the one-way gas valve.
US10898865B2 Polymer-carbon nanotube nanocomposite porous membranes
This invention relates to an asymmetric composite membrane containing a polymeric matrix and carbon nanotubes within a single membrane layer, where the carbon nanotubes are randomly oriented within the polymeric matrix and the composite membrane is formed by phase inversion. This invention also relates to a method for producing the composite membrane which includes: coating a surface with a film of a polymer solution containing a polymeric matrix and carbon nanotubes dissolved in at least one solvent; immersing the coated surface in a non-solvent to affect solvent/non-solvent demixing resulting in phase inversion to form a carbon nanotube-containing membrane; and optionally, removing the carbon nanotube-containing membrane from the surface. The invention also relates to a desalination method using the composite membrane.
US10898854B2 Alkali enrichment mediated CO2 sequestration methods, and systems for practicing the same
Methods of sequestering CO2 from a gaseous source of CO2 are provided. Aspects of the methods include employing an alkali enrichment protocol, such as a membrane mediated alkali enrichment protocol, in a CO2 sequestration protocol. Also provided are systems for practicing the methods.
US10898853B2 Device and system for decomposing and oxidizing gaseous pollutant
The invention provides a device and system for decomposing and oxidizing of gaseous pollutants. A novel reaction portion reduces particle formation in fluids during treatment, thereby improving the defect of particle accumulation in a reaction portion. Also, the system includes the device, wherein a modular design enables the system to have the advantage of easy repair and maintenance.
US10898852B2 Processes for removing a nitrogen-based compound from a gas or liquid stream to produce a nitrogen-based product
The present invention is directed to a process for removing gas phase nitrogen-based compounds by absorption into a liquid stream. The absorbed nitrogen-based compound is reacted with an acid to produce a nitrogen-based product. The nitrogen-based compound, the acid, and the resulting nitrogen-based product may be organic compounds, i.e. compounds derived from animal matter or plant matter. The nitrogen-based product may be a fertilizer, such as ammonium acetate or ammonium citrate that may be certified as organic. Processes are also described for removing nitrogen-based compounds from a liquid stream to produce a nitrogen-based product, including organic fertilizers. One process includes producing cavitation bubbles into which a liquid phase nitrogen-based compound is stripped, followed by absorption to produce a nitrogen-based product. Another process includes the use of a degassing membrane to remove a liquid phase nitrogen-based compound that is degassed to produce a nitrogen-based product, including organic fertilizers.
US10898851B2 Systems and methods for removal of mercury and/or hydrochloric acid from gas streams using calcium-containing particles
Several embodiments of the present technology are directed to the removal of one or more air pollutants using cooling and/or calcium-containing particles. In some embodiments, a method for removing air pollutants comprises flowing a gas stream having calcium-containing particles and one or more of mercury or hydrochloric acid molecules, and cooling the gas stream, thereby causing at least a portion of the calcium-containing particles to adsorb to the mercury and/or hydrochloric acid molecules in the gas stream. The method can further comprise, after cooling the gas stream, filtering the gas stream to remove at least a portion of the calcium-containing particles having adsorbed mercury and hydrochloric acid.
US10898849B2 Smart dehumidifier
A device is disclosed for extracting water from a fluid medium. The water extracting device comprises a primary channel and a quantity of a light-activated, stimulus responsive polymer (SRP) supported on a carrier within the primary channel. The SRP is capable of absorbing a quantity of water from the medium in a first state and releasing the water in a second state and vice versa. An illumination arrangement allows selective exposure of the SRP within the primary channel to electromagnetic radiation to switch the SRP between the first state and the second state whereby water absorbed by the SRP is released. Also disclosed is a method and device for conducting heat from the primary channel to a secondary channel, adjacent to and in heat conducting relation with the primary channel.
US10898846B1 Method and system for CO2 capture from flue gas and distributed for agricultural purposes
The flue gas extraction system provides extraction, collection, dilution, cooling, and distribution of flue gas from a vent stack of a stationary flue gas generator. The collected flue gas is processed through the system to achieve optimal temperature, pressure, flowrate, and water content for application to plants for increasing plant productivity and sequestering the carbon dioxide. The processed flue gas may be enriched with additional carbon dioxide and/or have nutrients added to it to realize a gas concentration which, when applied to plants, promotes the growth, health and productivity of the plants. Application of carbon dioxide may be supplemented by providing additional components to the plants which maintain a level of fertilization and irrigation suitable for the increased biomass and water utilization efficiency of the plants resulting from the increased intake of carbon dioxide.
US10898845B2 Mobile dust extraction device
A mobile dust extraction device for filtering air, the mobile dust extraction device including a filter housing having at least one air filter, an inlet housing fluidly connected to the filter housing, a fan assembly including a fan, a fan inlet and a fan outlet, the fan assembly fluidly connecting the filter housing to the fan outlet, a support frame for supporting the filter housing, inlet housing and the fan assembly and a drive mechanism for propelling the mobile dust extraction device.
US10898844B2 Clean-air filtration system and method of operating the clean-air filtration system
A clean-air filtration system has a main pipe with an entry for attaching to an exhaust source and an exit. The main pipe has a plurality of openings for dispersing water within the main pipe. A water source is connected to the main pipe and supplying water to the openings. A particulate interceptor is connected to the main pipe for removing particulates from an exhaust flow. A particulate storage unit is connected to the particulate interceptor.
US10898843B2 Reusable air filter
An air filtration system is provided. The air filtration system embodies filtration material supported by a frame, wherein the air filtration system provides two framed filtration materials sandwiching a fabric filter. Such framework may be removably engaged through magnetic forces. The filtration material may hold and/or carry electrostatic forces and/or magnetostatic forces induced through a current from an electrical power source and/or magnetic forces of the magnetics.
US10898841B2 Filter element, in particular for gas filtration
A filter element has a filter medium body with a first side and an oppositely positioned second side, wherein one of the first and second sides is the inflow side of the filter medium body and the other one is the outflow side of the filter medium body. A first sealing or supporting element is arranged at the first side. A second sealing or supporting element is arranged at the second side. At least one force-transmitting adhesive bead extends between the first side and the second side, wherein the at least one adhesive bead is a force transmitting element extending between the first and second sealing or supporting elements.
US10898836B2 Filter with exterior and interior media components and method of filtering
The invention features a filtration segment having a top seal, a bottom seal and a primary filter core and the method of filtering with the design of the filtration segment. The primary filter core is operatively coupled to at least one opening which is located either on the top seal or on the bottom seal. The filtration segment also includes one or more interior filters surrounding the primary filter core. Each interior filter includes a filter material surrounding a secondary core which is operatively coupled to at least one opening which is located either on the top seal or on the bottom seal. Each filter may optionally include a retaining medium enclosing the filter material. The filtration segment has one or more layers of an exterior filter media which operatively surround the interior filters and are operatively coupled to the top seal and the bottom seal.
US10898826B2 Compact containerized system and method for spray evaporation of water
A wastewater evaporation system for spray evaporating water comprising: a wastewater feed inlet; a pump, wherein the wastewater feed inlet is fluidly connected to the pump and wherein the pump is fluidly connected to a manifold; a drip orifice, wherein the manifold is fluidly connected to the drip orifice; a container, wherein an upper portion of the container is enclosed with a demister element; a packing and/or tray system disposed within the container, wherein the drip orifice discharges water droplets onto the packing and/or tray system; a discharge outlet, wherein a bottom of the container is fluidly connected to the discharge outlet; and an air system, wherein the air system discharges air flow counter to the water droplets from the drip orifice. A method of spray evaporating water while limiting emission of particles regulated as pollutants is also disclosed.
US10898819B2 Toy vehicle track systems and connectors for same
Toy vehicle track systems and connectors for those systems are disclosed. The connectors include a central portion, first and second end portions, and first and second side portions. The central portion includes first and second posts, and a third larger post disposed between the first and second posts. In some embodiments, the third post includes a living hinge to allow for increased vertical displacement of the first, second, and/or third posts when a downward force is applied to the third post. In some embodiments, the central portion includes descending and ascending parts to allow for increased vertical displacement of the first, second, and/or third posts when a downward force is applied to the third post. In some embodiments, the connectors include a plurality of bumps to increase frictional engagement between the connector and the track sections.
US10898814B2 Virtual gaming system and method
A virtual interactive archive video sports game configured to generate a virtual gaming match between two opponents is disclosed. The system includes a user input, a video clip database, a challenges database, a display and a processor. The user input is configured to receive at least one opponent selection input and at least one challenge selection input. The video clip database is configured with a plurality of video clips between the two opponents. The challenges database is configured with a plurality of challenges relating to the video clips in the video clip database. The display is configured to present the video clips, challenges and results data to the user. The processor is configured with a virtual match selection engine configured to randomly select more than one video clip between the two opponents, a challenge selection engine configured to randomly select at least one challenge from the challenge database and receive at least one challenge selection input and a results engine configured to generate results data based on whether or not the challenges are met by the randomly selected video clip, between the two opponents.
US10898812B2 Methods, devices, and systems for interactive cloud gaming
The various implementations described herein include methods, devices, and systems for interactive cloud gaming. In one aspect, an interface device with processors and memory storing an application program is used for cloud gaming. The interface device includes a communication module for receiving and/or transmitting messages and media streams between the interface device, a game controller, and a remote gaming server. The interface device further includes an output module configured to provide output of the application to an input of a display device coupled to or integrated with the interface device. The application is configured to implement a first mode in which the interface device processes and displays outputs associated with substantially all messages transmitted by the game controller, and a second mode in which the interface device processes and displays a predefined subset of messages from the game controller and displays gaming media streams from the gaming server.
US10898810B2 Method and apparatus for enhancing a gaming experience
A method includes communicatively coupling a physical object with a body. One or more of the body or the physical object has connectivity to a computer having a processor. The method also includes detecting a contact position between the physical object and the body. The method further includes setting a function of the physical object based on the contact position. The method additionally includes generating a virtual representation of the physical object and the body in a virtual reality viewable by way of a display associated with the computer. Generation of the virtual representation of the physical object and the body includes orienting a virtual version of the physical object with respect to a virtual version of the body based on the contact position. The method also includes causing the virtual version of the physical object to be usable in accordance with the function of the physical object.
US10898809B2 Overlaying content within live streaming video
Systems and methods are provided for integrating supplemental overlay content within streaming video content that is to be broadcast to viewer devices. The overlay content to include in the streaming video content may be dynamically determined during video streaming and incorporated within individual frames of the video data, such as by a computing device of a user who is broadcasting his play of a video game or other activity, prior to the user's computing device sending those video frames (with embedded overlay content therein) to a streaming platform to be broadcast to potentially many viewers' devices.
US10898801B2 Selecting properties using handheld controllers
Described herein are, among other things, techniques to enable a user to navigate a color picker or other graphical-user-interface (GUI) tool using an input device of a handheld controller. For example, a user may operate a color picker presented on a display by pressing upwards on a joystick to activate selection of hue, down and to the left to activate selection of saturation, and down and to the right to activate selection of lightness or value.
US10898800B2 Cloud gaming device handover
Methods and systems to identify options of secondary client devices for a device handover of game play include establishing a session of game play of a game for a primary client device by executing the game on a server for streaming video frames to the primary client device. A request is received to generate a profile of one or more secondary client devices that are identified to be local to the primary client device. The profile is configured to identify device attributes for the secondary client devices. A handover option is provided to the primary client device during game play, identifying one or more of the secondary client devices, based on the profile. A selection of a secondary client device identified by the handover option received from the primary client device causes pausing of the streaming of video frames to the primary client device, saving a game state for the game and providing an option to resume play of the game on the secondary client device. A resume request received from the secondary client device causes the game state for the game to be accessed and game play resumed so as to continue streaming video frames to the secondary client device.
US10898799B2 Gaming accessory with sensory feedback device
A method that incorporates teachings of the subject disclosure may include, for example, receiving, by a device comprising a processor, a first signal from a motion-sensitive component of the device; receiving, by the device, a second signal from a touch-sensitive interface of the device, detecting, by the device, from a combined signal comprising the first signal and the second signal, a selection of a portion of the device; and causing, by the device, a sensory feedback generator to provide a feedback signal in accordance with the combined signal. The feedback signal may comprise an audible sound, a visual effect, a tactile effect, or any combination thereof. Additional embodiments are disclosed.
US10898798B2 Directed wind effect for AR/VR experience
An air flow generator may be implemented on an augmented reality (AR) or virtual reality (VR) controller or head-mounted display (HMD) through which an AR or VR experience is presented. Based on content upon which the AR or VR experience is based, air flow effects can be provided by the air flow generator. In particular, desired air flow effect parameters based on or obtained from the content, can be used to enhance the AR or VR experience through generating air flow directed at a user of the HMD. The air flow generated by the air flow generator can be further enhanced by the addition of liquid and/or scented additives.
US10898797B2 Electronic controller with finger sensing and an adjustable hand retainer
An electronic controller includes a controller body having a head that adjoins a handle at a neck region, and that includes at least one thumb-operated control. The controller includes a hand retainer that in a closed position is configured to physically bias the user's palm against an outer surface of the handle. The hand retainer includes a resilient member that biases the hand retainer towards an open position. An adjustment mechanism couples the resilient member to the head and permits the resilient member to be adjusted betweena plurality of discrete positions to adjust the resilient member towards or away from the user's purlicue. The adjustment mechanism may include an anchor that is movable peripherally about the head between the plurality of discrete positions and is pivotably attached to the resilient member with a two-part fastener, with a friction member interposed between the resilient member and the anchor.
US10898794B2 Gaming support assembly and controller holster
A gaming support apparatus that includes a holster body is provided. The holster body receives a gaming controller disposed therein and includes a peripheral wall. The peripheral wall, in an operational configuration, partially encloses the gaming controller received by the holster body. The holster body further includes a support web that, in the operational configuration, supports the gaming controller received by the holster body. The holster body further includes at least one opening in the holster body that, in the operational configuration, allows access to one or more input elements of the gaming controller received by the holster body. In the operational configuration, the holster body supports the gaming controller such that a user may actuate the one or more input elements of the gaming controller without supporting the weight of the gaming controller.
US10898790B2 Puzzle
A puzzle kit and a puzzle constructed from said puzzle kit. The puzzle kit comprises a three dimensional substrate having an outer surface, and a plurality of puzzle pieces that cannot interlock. Each puzzle piece has a first surface and an opposite second surface and a thickness defined between the first and second surfaces. Each puzzle piece comprises first attachment means and the outer surface of the substrate defines a plurality of complementary second attachment means, such that the first attachment means and the second attachment means magnetically attach each puzzle piece to the outer surface. The first attachment means comprises a projection extending from the second surface of the puzzle piece. The second attachment means comprises a hole to partly receive the projection.
US10898784B2 Integrated timing system and method having a highly portable RFID tag reader with GPS location determination
A system and method for determining a time of an event participant passing a detection point having a participant identifier number by a timing system coupled to an RFID tag reader in proximity to at a monitored point and receiving RFID tag read times and coupled to a portable device with a transceiver and a location detector for selectively receiving a participant number read, the timing system receiving the geographic location of the handheld device, the handheld read participant number and a handheld time, determining that the received RFID tag read times timing system are not usable times and determining a time of passing of the participant by the detection point by determining a delta time between the proximity detector and the handheld device and an adjusted time of participant passing based on the determined delta time and handheld time.
US10898763B2 Apparatus for charging and maintaining luminescent objects
A light charging system charges at least one luminescent object to emit light and includes a housing comprising an openable lid, an interior, and at least one interior wall, wherein the openable lid provides a light proof seal when mated with the at least one interior wall. A light source comprises an illuminating light panel interposed between at least one light source and the interior to illuminate and charge a luminescent object when operating. An electronic housing contains at least one battery and an on/off switch. A/C or D/C power can be used.
US10898759B2 Determination and presentation of customized notifications
Notifications for instructing user behavior can be determined and presented when appropriate. Historical fitness data and current fitness data are accessed. This data is used to determine whether a user fitness goal is likely to be achieved. If not, a notification may be determined and presented at a user device.
US10898758B2 Measurement system for use in an exercise machine
A measurement system for use in an exercise machine, which exercise machine comprises a lifting mechanism and an engaging member for selectively engaging a number of stacked weights to the lifting mechanism, the measurement system comprising a pair of cooperating members including a range meter and a reflector member, wherein one of the cooperating members is connected to the lifting mechanism and the other of the cooperating members is connected to the engaging member, wherein the range meter is directed to measure a distance to the reflector member to determine a distance which correlates to the weight of the selectively engaged weights.
US10898757B1 Three dimensional object tracking using combination of radar speed data and two dimensional image data
Methods, systems, and apparatus, including medium-encoded computer program products, for 3D flight tracking of objects includes, in at least one aspect, a method including: obtaining 2D camera image data of a golf ball; modeling a 2D trace of the golf ball using the 2D image data; obtaining radar speed data of the golf ball; modeling a speed of the golf ball using the radar speed data, wherein modeling the speed of the golf ball includes fitting a polynomial function to a first portion of the radar speed data and fitting an exponential function to a second portion of the radar speed data; combining the modelled speed of the golf ball with the modelled 2D trace of the golf ball to form a 3D trace of the golf ball; and outputting for display the 3D trace of the golf ball in 3D space.
US10898754B2 Gym tower
A gym tower which includes a base and a plurality of internal weights vertically stacked on the base. A frame is connected to the base and extends upward from the base to engage with the plurality of internal weights. A top plate is connected to the frame, so that the base and the plate enclose the plurality of internal weights within the frame. The tower also includes a spine is adapted to selectively engage the plurality of internal weights. A main pulley is connected to the top plate and a main cable is fed through the main pulley. The main cable is connectable to the spine at a first end and includes a connector device at a second end. The tower also includes a rod adapted to engage with the spine and to select an internal weight and is adapted to secure to external weights.
US10898753B2 Treadmills having adjustable surface stiffness
In one embodiment, an adjustable surface stiffness treadmill includes a treadmill unit, a scissor mechanism that supports the treadmill unit, a stiffness adjustment mechanism configured to adjust a vertical stiffness of the treadmill unit, and an input link having a first end and a second end, the first end being connected to the scissor mechanism and the second end being connected to the stiffness adjustment mechanism, wherein the input link translates downward vertical forces imposed upon the treadmill unit into horizontal forces imposed upon the stiffness adjustment mechanism.
US10898751B2 Strap-based exercise system
The invention is a strap-based suspension exercise system that includes a main strap that is attached to a fixed or stationary object to anchor the exercise system and exercise straps that are used to perform a variety of exercises. Different main straps are provided that enable anchoring the exercise system virtually anywhere. The exercise straps, which may be inelastic or elastic are attached to the main strap using a uniquely designed buckle and include a safety strap. Various optional equipment, such as a foot hammock, a wrist or foot strap, additional handles, exercise straps with gym rings, and a vest worn by the user are provided.
US10898746B2 Fire protection nozzle, fire protection sprinkler, fire protection systems, and methods of manufacturing a fire protection nozzle and a fire protection sprinkler
A fire protection nozzle includes a body having two frame arms having proximal ends connected to an outlet of the body, and distal ends, the two frame arms defining a frame arm plane, and a junction formed by the distal ends of the frame arms, the junction including a central bore and a cylindrical outer wall. A circular deflector is mounted to the body, and includes a planar disk having a mounting hole in a center of the planar disk to receive the cylindrical outer wall of the junction, and a plurality of slots on a periphery of the circular planar disk. The plurality of slots includes four radial first slots, four radial second slots, eight radial third slots, and eight fourth slots. The nozzle has a K-factor of at least 28 gpm/(psi)1/2.
US10898745B2 Sprinkler drop bracket for intersecting downlight
A sprinkler support assembly includes a ceiling system including a suspension frame and a grid support, the grid support extending laterally outward from the suspension frame; and a bracket assembly including a main body and at least one support arm, the main body attached to the grid support, the at least one support arm extending outward from the main body.
US10898744B2 Automatic fire extinguishing system for small spaces using fire extinguishing agents
An automatic fire extinguishing system has a tank that contains fire extinguishing agents, and a housing. The housing has a glass bulb retained therein where the glass bulb is exposed by a side connecting hole, and contacted by a moving member that is biased by an elastic body against the glass bulb. When heat is transferred via the side connecting hole to the glass bulb to break the glass bulb, the elastic body biases the moving member to cause the guiding bars to push a striking member so that a striking protrusion on the striking member breaks a membrane that covers the opening of the tank, thereby allowing the pressurized fire extinguishing agents to escape.
US10898736B2 Implants using ultrasonic waves for stimulating tissue
Described herein are implantable devices configured to emit an electrical pulse. An exemplary implantable device includes an ultrasonic transducer configured to receive ultrasonic waves that power the implantable device and encode a trigger signal; a first electrode and a second electrode configured to be in electrical communication with a tissue and emit an electrical pulse to the tissue in response to the trigger signal; and an integrated circuit comprising an energy storage circuit. Also described are systems that include one or more implantable device and an interrogator configured to operate the one or more implantable devices. Further described is a closed loop system that includes a first device configured to detect a signal, an interrogator configured to emit a trigger signal in response to the detected signal, and an implantable device configured to emit an electrical pulse in response to receiving the trigger signal. Further described are computer systems useful for operating one or more implantable devices, as well as methods of electrically stimulating a tissue.
US10898723B2 Scanning mechanism and treatment method for LLLT or other light source therapy device
A scanning mechanism to scan a light source, such as a low-level laser, to create a desirable energy distribution on a treatment area. The light source may include multiple light beam generators, each having a different wavelength and each having a different energy distribution. The scanning mechanism can be programmable to scan in different patterns in accordance with a desired treatment.
US10898721B2 Telemetry overuse reduction in a medical device
Systems, apparatus, methods and computer-readable storage media facilitating telemetry overuse reduction in a medical device, such as an implantable medical device (“IMD”) are provided. In one embodiment, an IMD includes a housing configured to be implanted at least partially within a patient, a memory and circuitry within the housing and a processor that executes executable components stored in the memory. The executable components include: a communication component configured to establish a telemetry connection with an external device to communicate data associated with sensed physiological data or therapy; and an authorization component configured to determine whether the external device is authorized to communicate with the IMD, wherein the communication component is further configured to disable the telemetry connection with the external device and prevent additional communication with the external device for a defined period of time based on a determination that the external device fails to be authorized to communicate with the IMD.
US10898720B2 Impedance sensing
In some examples, a medical device system includes an electrode. The medical device system may include impedance measurement circuitry coupled to the electrode, the impedance measurement circuitry may be configured to generate an impedance signal indicating impedance proximate to the electrode. The medical device system may include processing circuitry that may be configured to identify a first component of the impedance signal. The first component of the impedance signal may be correlated to a cardiac event. The processing circuitry may be configured to determine that the cardiac event occurred based on the identification of the first component of the impedance signal.
US10898718B2 Sensor-based pain management systems and methods
This document discusses, among other things, systems and methods for managing pain of a subject. A system includes a first sensor circuit to sense a first signal indicative of a functional state of the subject, a second sensor circuit to sense a second signal different from the first signal, and a controller circuit. The controller circuit may determine an operating mode of the second sensor circuit according to the sensed first signal, trigger the second sensor circuit to sense the second signal under the determined operating mode, and generate a pain score using at least the second signal sensed under the determined operating mode. The pain score may be output to a patient or used for closed-loop control of a pain therapy.
US10898717B2 Device and method for snoring detection and control
A device for the treatment of snoring is provided. The device may include a flexible substrate configured for removable attachment to a subject's skin, a primary antenna disposed on the flexible substrate, an interface configured to receive a feedback signal that varies based upon a breathing pattern of the subject; and at least one processing device. The processing device may be configured to analyze the feedback signal and determine whether the subject is snoring based on the analysis of the feedback signal, and if snoring is detected, cause a hypoglossal nerve modulation control signal to be applied to the primary antenna in order to wirelessly transmit the hypoglossal nerve modulation control signal to a secondary antenna associated with an implant unit configured for location in a body of the subject.
US10898714B2 Stimulation suspension in response to patient discomfort or state
Systems and methods are provided for delivering neurostimulation therapies to patients. Stimulation from an implantable medical device (IMD) may be suspended in response to detecting a patient discomfort event, such as a cough, throat irritation, or voice alteration. The suspension period may be based on at least one of a severity level of the patient discomfort event and a patient physical state, such as being asleep or lying down. Detection of a patient discomfort event may be calibrated.
US10898713B2 Uses for eye tracking in a visual prosthesis
The present invention is an improved system for use of eye tracking including spatial mapping percepts in a visual prosthesis by presenting an electrically induced precept through a visual prosthesis, requesting a subject look to the direction of the percept and tracking their eye movement. Eye movement is both faster and more accurate than asking a visual prosthesis user to point to the location of a percept. This method can be beneficial in a retinal prosthesis, but is particularly useful in a cortical visual prosthesis where visual cortex does not match the retinotopic map. Methods are presented for calibrating an eye tracker. Eye tracking hardware may also be used for blanking video information base on the subject's natural blink reflex.
US10898712B2 Robust instantaneous frequency estimation for hearing prosthesis sound coding
A signal processing arrangement generates electrical stimulation signals to electrode contacts in an implanted cochlear implant array. An input sound signal is processed to generate band pass signals that each represent an associated band of audio frequencies. A characteristic envelope signal is extracted for each band pass signal based on its amplitude. Stimulation timing signals are generated for each band pass signal, including for one or more selected band pass signals using a timing function defined to: i. represent instantaneous frequency as determined by the band pass signal temporal fine structure features, and ii. exclude temporal fine structure features occurring within a time period shorter than a band-specific upper frequency limit. The electrode stimulation signals are produced for each electrode contact based on the envelope signals and the stimulation timing signals.
US10898711B1 Thinking cap: combining personalized, model-driven, and adaptive high definition trans-cranial stimulation (HD-tCS) with functional near-infrared spectroscopy (fNIRS) and electroencephalography (EEG) brain state measurement and feedback
Described is system for mapping user behavior to brain regions of interest. Using a cognitive-behavior model, a behavioral task is selected that is suited for a desired brain state. Using a functional-anatomical model coupled to the cognitive-behavior model, a set of high-definition neurostimulations is selected to be applied to the user during performance of the selected behavioral task. The selected set of high-definition neurostimulations targets specific regions of the user's brain. Changes in the user's brain state are sensed during application of the set of high-definition neurostimulations and performance of the selected behavioral task using at least one brain monitoring technique. The coupled functional-anatomical and cognitive-behavior models are adapted until the desired brain state is reached.
US10898706B2 Systems, methods, and devices for brain stimulation and monitoring
Provided are systems, methods, and devices for brain stimulation and monitoring. Brain stimulation may be provided to enhance slow wave and spindle synchrony. Such stimulation may provide increased memory consolidation. Furthermore, brain stimulation modalities may provide enhanced sleep and awakening. For example, transcranial direct current stimulation of the brain stimulation may enhance sleep quality. Moreover, one or more markers characterizing unconsciousness are may be identified based on changes in measured power densities or spectra. Further still, the above described modalities of brain stimulation may be implemented in an open-loop or closed loop manner. Brain state parameters may be generated for building models of the brain based on determined synchrony patterns between slow waves and spindles. The models may be used to determine a mediation procedure for adjusting the intensity of slow wave oscillations to enhance slow wave and spindle synchrony.
US10898704B2 Tattoo machine having an arm-mounted power supply
An arm-mounted motorized tattooing instrument includes a skin-perforating ink delivery wand configured for hand-held operation by a human operator, a wrist-or-forearm-mountable power supply, and a means for electrically coupling the skin-perforating ink delivery wand to the power supply. The instrument is configured to allow the human operator to operate the ink delivery wand without loss of power when rotating the ink delivery wand by hand about any of three orthogonal axes with the power supply mounted to a wrist or forearm of the same hand.
US10898703B2 Microneedle template and microneedle prepared using the same
Provided are a microneedle template including: a substrate on which at least one microneedle shapes are formed; and a diamond layer formed on the surface of the at least one microneedle shapes, a method for preparing the microneedle template, a microneedle prepared using the microneedle template, and a method for preparing the microneedle.
US10898702B2 Devices and methods for applying body lotions such as sunscreens
Hand-held articles for applying lotion to a user, including a user's back or other hard-to-reach places have a housing containing a lotion to be dispensed, and a roller, integral to the housing, that transfers the lotion to a user's body. A spring or pump mechanism pushes the lotion in the housing towards the roller.
US10898700B2 Balloon catheters for body lumens
Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.
US10898698B1 Devices with dimensions that can be reduced and increased in vivo, and methods of making and using the same
Devices are provided with an internal dimension that can be reduced and increased in vivo. In one example, an interatrial shunt for placement at an atrial septum of a patient's heart includes a body. The body includes first and second regions coupled in fluid communication by a neck region. The body includes a shape-memory material. The body defines a passageway through the neck region for blood to flow between a first atrium and a second atrium. The first and second regions are superelastic at body temperature, and the neck region is malleable at body temperature. A flow area of the passageway through the neck region may be adjusted in vivo.
US10898697B2 Male insert for draining fluid from a patient
A male insert for draining fluid from a patient is provided. The male insert includes a housing, a valve stem supported by the housing for pivotal movement about an axis from an extended position allowing insertion into the patient to a retracted position preventing re-insertion into the patient, a tube connected to the valve stem and supported by the housing for rotational movement about the axis, the tube and the valve stem forming a contiguous channel through which the fluid drains, a stop preventing rotational movement of the tube in a first position and allowing rotational movement of the tube in a second position, and a locking tab engaging one of the valve stem and the tube when the valve stem is in the retracted position.
US10898694B2 Balloon design to reduce distal length
A device and system for thermally affecting tissue that includes a balloon catheter with a reduced distal length for ease of navigation and that also includes a balloon that is more resistant to bursting and delamination. The balloon may include a proximal neck generally attached to an elongate body and a distal neck generally attached to a shaft disposed within the elongate body. The distal neck is turned inward to extend within the balloon chamber and the proximal neck may either extend within the chamber or extend proximally away from the balloon chamber. Alternatively, the device may include an inner balloon and an outer balloon, the distal necks of both being turned inward and extending within the inner balloon chamber. The proximal necks may both also be turned inward to extend within the chamber or the proximal neck of the outer balloon may extend away from the balloon chamber.
US10898690B2 Vascular access disassembling needle device and method
A vascular access disassembling needle assembly 20 is provided that enables rapid insertion of a guide wire into the needle and subsequent rapid removal of the access needle off the guide wire by facile disassembly of the needle. The disassembling needle assembly 20 includes a needle portion 30 wherein the needle breaks apart by splitting along at least one seam 40 that extends from the proximal to the distal end to allow removal of the guide wire. Various mechanical features are described that can facilitate the separation of the needle body along at least one seam. Once one or more seams are separated, the needle body may be removed from the guide wire without the need to withdraw the needle along the length of the guide wire, which permits preloading of expanders and other medical devices onto the guidewire.
US10898688B2 Needleless connector loosening device
A tool for loosening a needleless connector is provided. The tool is a holder for holding a catheter port connected to the needleless connector. The holder includes a front surface, a rear surface, a top surface, and a cavity. The cavity accommodates the catheter port. The cavity extends through the holder and has a front opening in the front surface, a rear opening in the rear surface, and a rear inner wall. The cavity is defined by at least a first cross-sectional dimension and a second cross-sectional dimension, the first cross-sectional dimension at least partially defining a front section opening to the front opening, the second cross-sectional dimension at least partially defining a rear section opening to the rear opening.
US10898684B2 Non-buckling steerable catheter
A steerable member is disclosed generally having a steerable member for a medical apparatus, including a continuous, elongated body having a proximal section, a distal section, and a middle section between the proximal and distal sections, where the proximal section of the elongated body is less flexible than the distal section. At least one pull wire sheath extends through the proximal section and the middle section, but not through the distal section, and has a channel therethrough. A pull wire is disposed in the channel of the sheath and extends through the proximal section, middle section and distal section of the elongated body, the pull wire having a distal end affixed to a distal end of the elongated body, so that the distal section of the elongated body bends in response to a force applied to the proximal end of the pull wire.
US10898683B2 Catheter constructions
Polymeric tubing, for use with catheters or other medical devices, where the polymeric tubing can have regions of customized properties including, but not limited to, durometer, torque control, flexibility, axial strength, stiffness, etc. One variation of the device allows for transitions between regions to be configured such that there can be gradual or customized transitions between various regions such that the structural characteristics differential between the regions selectively designed. Additional variations include outer layers having a plurality of material sections extending in a spiral direction along the axial length to form a continuous wall of the outer layer. In certain variations, the structural characteristic differential is minimized or eliminated as compared to conventional catheters.
US10898682B2 Microtube guide
A microtube guide has a microtube combined with a free-floating and removable core. The microtube is generally hollow with a tube shaft and a distal ring, the tube shaft and the distal ring formed from flexible plastic. The distal ring is conformable to the core and straightenable for insertion into a patient's body, and deploys when the core is withdrawn to form a loop. The core is received by the microtube and is configured to advance into the distal ring to cause a diameter of the distal ring to expand, retract, or straighten. The distal ring diameter is thus adjustable by the user.
US10898678B2 Segmented arch fulcrum support catheter and method of use
The present disclosure teaches a medical device and method of use, employing a tube which is composed of segments and bends capable being configured into unique shape that allows said device to use the lesser (inferior) curve of aortic Arch and other vessel structures as as fulcrums of support for a guide catheter, for subsequent prevention of recoil and displacement thereof, while delivering additional catheters or devices into the distal branches of the great vessels. A method for using same.
US10898676B2 Urinary catheter having a conical proximal section
A urinary catheter has a tube having a proximal section that is insertable into a urethra and a distal section having a connector secured to a distal end of the tube. A lumen is formed longitudinally in the tube and a hydrophilic coating applied to an exterior surface of the tube. The proximal section of the tube includes a proximal tip end that is closed to terminate the lumen at the proximal tip end, with the proximal tip end rounded for insertion of the proximal tip end through the urethra and into a bladder. The proximal section of the tube is conical such that a first outer diameter of the proximal section of the tube measured at the proximal tip end is smaller than a second outer diameter of the proximal section of the tube measured distal from the proximal tip end.
US10898675B2 Urinary catheters having limited reusability
A reusable urinary catheter assembly includes a catheter shaft and a plurality of removable members associated with the catheter shaft. A different one of the removable members is configured to be removed from the catheter shaft between each consecutive use of the reusable urinary catheter assembly. By such a configuration, the number of times that the reusable urinary catheter may be reused is limited by the number of removable members.
US10898674B2 Methods and devices to clear obstructions from medical tubes
A device for clearing obstructions from a medical tube, such as a chest tube, is disclosed in various embodiments. The device features a clearance member in the form of a loop. The loop desirably has a diameter that substantially corresponds to the inner diameter of the medical tube. Also desirably, the loop presents a substantially unobstructed pathway therethrough for the flow of material from a location in the medical tube distal to the loop to a location in the medical tube proximal to the loop regardless whether the clearance member is being translated or is at rest in the medical tube. Methods of utilizing such a device are also disclosed.
US10898670B2 Method and apparatus for increasing therapy compliance
A breathing assistance unit for providing pressurized heated humidified air to a user increases user compliance. The breathing assistance unit generates positive emotional and cognitive states of a user about the therapy.
US10898668B2 Plastic to textile coupling for a patient interface and methods of manufacturing same
A manufactured component, such as headgear or a headgear strap, for a patient interface for delivery of a supply of pressurised air or breathable gas to an entrance of a patient's airways may include a textile portion having a first material with a first melting point. It may also include a plastic portion over-moulded to the textile portion. The plastic portion may be formed of a second material having a second melting point. The melting points may be different such that the second melting point is chosen to be less than the first melting point of the first material. The component may be moulded in a multi-step process that moulds separate portions of the plastic portion and the textile portion at different times. The resulting plastic portion may then have a mechanical bond with the textile and may do so without significant chemical bonding between the plastic portion and the textile.
US10898665B2 System for ventilating patients
A system (1) for ventilating patients includes a gas passage unit (2), which has a first inlet opening (6) with a fluid-communicating connection to a pressurized gas source (12, 13) and an outlet opening (9) connected to the first inlet opening (6) in a manner. A patient interface (3), for ventilation, includes an interface inlet opening (10). A gas line element (4) has a fluid-communicating connection to the outlet opening (9) and to the interface inlet opening (10). A controllable pressure change element (5) is provided between the first inlet opening (6) and the interface inlet opening (10). A second inlet opening (8) has a fluid-communicating connection to the gas line element (4). A control unit (7) controls the controllable pressure change element (5). A device or a system (1), which provides fully adequate ventilation with high performance with minimal expenditure for hardware, is provided.
US10898664B2 Ventilator apparatus and method
A respiratory treatment apparatus configured to provide a flow of breathable gas to a patient, including a breathable air outlet, an outside air inlet, and an pneumatic block module, wherein the pneumatic block module includes: a volute assembly including an inlet air passage, a mount for a blower and an outlet air passage; the blower being mounted in the mount such that an impeller of the blower is in a flow passage connecting the inlet air passage and the outlet air passage; a casing enclosing the volute assembly, wherein air passages within the casing connect air ports on the volute assembly, wherein the inlet air passage of the volute assembly is in fluid communication with the outside air inlet and the outlet air passage of the volute assembly is in fluid communication with the air outlet.
US10898663B2 Fan unit with improved surge characteristics
A fan unit that forms part of a gases supply unit used as part of a breathing assistance system for providing heated gases to a user is provided. The fan unit has an impeller surrounded by an upwardly sloped surface to facilitate improved airflow performance under surge conditions. The impeller includes a plurality of blades capped by a lid having a central aperture to provide an inlet to the impeller.
US10898662B2 Patient interface with venting
Interfaces for positive pressure therapy having various vent designs are disclosed herein. The interfaces include a bias flow vent with design geometries that help reduce and/or minimize draft and noise levels of the fluids exiting the vents. Some of the vent designs include particular vent hole geometries, plenum spaces, diffusers and fibrous media.
US10898657B2 Manual injection device
A manual injection device having a lower body and a fluid reservoir that moves axially in the lower body. The reservoir includes a piston and needle; an upper body mounted to move axially relative to the lower body, the upper body including a piston rod co-operating with the piston; and a sleeve mounted to move relative to the lower body between a rest position and a projecting position. The sleeve is blocked in its rest position before the injection device is actuated, and urged automatically into its projecting position after injection. The piston rod co-operates with the reservoir to form an injection lock, the force for moving the reservoir axially being less than the force for triggering the injection lock, such that pricking is performed before injection. Before actuation, the piston rod is connected to a ring that is fastened on a radial collar of the reservoir.
US10898655B1 Auto-injectors featuring medicine delivery assurance
Auto-injectors can deliver many different types of medicines into people. One failure mode of auto-injectors is failing to insert the needle into the patient while the medicine is propelled from the auto-injector. This error results in the medicine not entering the patient's body. An auto-injector can include a syringe and probes to prevent medicine from being propelled if the person administering the injection does not position the auto-injector correctly.
US10898649B2 Syringe
In a general aspect, a syringe terminates the dispensing of a fluid based on a force applied to a plunger member of the syringe. In some aspects, a plunger member of a syringe includes a top portion, a bottom portion, and a contact portion. The top and bottom portions are in contact with the contact portion, and the bottom portion has a length greater than or equal to a length of the top portion. The contact portion permits the top portion to move independent of the bottom portion in response to a stress in the contact portion exceeding a critical stress. The stress in the contact portion is based on a first force applied to the top portion and a second force opposite the first force applied to the bottom portion.
US10898645B2 Intervertebral dosing device and method
Some embodiments of the invention include a cannulated bone screw including a screw shaft with screw thread, a proximal end, a distal end, and a channel extending through the screw shaft. Some embodiments include an inlet port coupled to the channel and extending through the distal end, and an outlet port coupled to the channel by a curved or angled channel region. In some embodiments, the outlet port extends through the screw shaft and exits a side that is substantially parallel to the shaft longitudinal axis. In some embodiments, the cannulated bone screw can form part of a therapy delivery device. In some embodiments, the outlet port extends through a portion of the screw shaft and exits at the distal end. In some embodiments, the valve includes a plunger with a plunger rod within the screw shaft, and a valve seat for control of fluid flow out of the screw.
US10898637B2 Controlled nucleation from gas-supersaturated liquid
Disclosed is a system to generate bubbles. The bubbles may be formed to include a substantially or medically pure gas. The bubbles may be formed on demand and in a selected small size.
US10898633B2 Devices and methods for extracorporeal conditioning of blood
The disclosure relates to devices and methods for extracorporeal conditioning of blood. Extracorporeal blood oxygenators and blood oxygenator components, such as conditioning modules, are described. An extracorporeal blood oxygenator includes a conditioning module having an external frame, an inlet cover, an outlet cover, and an internal chamber. A fiber assembly is disposed within the internal chamber and a potting material on the fiber assembly creates a circumferential seal that defines a passageway through the fiber assembly having a substantially circular cross-sectional shape. A fluid inlet is in fluid communication with the passageway, has a lumen that extends along an axis that is substantially perpendicular to the fiber assembly, and has an internal curvilinear surface adjacent the fiber assembly. A fluid outlet on the opposite side of the fiber assembly also has a lumen that extends along an axis that is substantially perpendicular to the fiber assembly.
US10898630B2 Peritoneal dialysis systems, devices, and methods
An automated peritoneal dialysis system provides both cycler-assisted peritoneal dialysis treatment. The system includes a fluid preparation and treatment device with concentrate dilution components connected to a source of purified water and medicament concentrate. The treatment device has at least one mixing container connected via a pump and valves to the sources, the valves and the pump mixing and diluting the concentrate to form a medicament. Conductivity sensors are provided for fluid quality measurement, calibration, error trapping, and fluid characterization.
US10898627B2 Ventricular assist device
A ventricular assist device for use in a human recipient includes a housing within which a series pair of turbine pump segments, each having a deswirler, are operative. The series pair of turbine pump segments provides a redundancy which in turn enhances the safety factor provided by the ventricular assist device.
US10898626B2 Catheter-based heart support system and method of implanting thereof
A device for circulatory support of the heart with holding means implanted intracardially in the left or right ventricular outflow of the heart by catheter, using an endovascular method, through a femoral access or a percutaneous transventricular, transseptal, transapical or transvenous access, the holding means comprises anchoring means fixed in the subcommissural triangle underneath the aortic valve and the pulmonary valve, in the flow direction of the blood on the ventricular side of the aortic valve and the pulmonary valve, a pump fixed in the holding means by a catheter, using an endovascular method, through a femoral access or a percutaneous transventricular, transseptal, transapical or transvenous access, the pump can be inserted releasably into the holding means after the holding means has been fixed by the anchoring means in the subcommissural triangles underneath the aortic valve and the pulmonary valve, or is connected to the collapsible and expandable anchoring means.
US10898625B2 System for introducing a pump
The invention resides in the field of introducing fluid pumps into a lumen and relates to a system for introducing a pump into a lumen which comprises a first sheath and a pump to be introduced into the first sheath, or a system which has a pump with a distal pump unit and a shaft catheter which emerges proximally to the pump unit. According to the invention one or two sheaths are used, the distal pump unit being pulled firstly into the distal end of one sheath, in order to avoid damage to a shaft catheter. Subsequently, the sheath receiving the pump unit is transferred into a further sheath or a receiving lumen.
US10898614B2 Tissue repair laminates
There are provided tissue repair laminates which promote cellular in-growth but also prevent or mitigate tissue adhesion. The laminates comprise a biodegradable polyurethane foam layer which facilitates cellular infiltration and a polyurethane barrier layer which is non-adhesive to tissue. The laminates resist shrinkage under in vivo conditions and possess desirable mechanical properties. The laminates find use in, for example, the repair of herniated tissue, particularly, but not limited to hernias in the abdominal wall.
US10898613B2 Hyaluronic acid gel with a divalent zinc cation
A method of preparing a sterilized injectable hydrogel composition, including the steps: a) covalently crosslinking a glycosaminoglycan using a bi- or polyfunctional crosslinking agent to form a covalently crosslinked glycosaminoglycan, b) swelling the covalently crosslinked glycosaminoglycan in a solution including a divalent cation to form a hydrogel composition, and c) sterilizing the hydrogel composition by autoclaving to form a sterilized injectable hydrogel composition, and to sterilized injectable hydrogel compositions obtainable by such method.
US10898611B2 Cancellous bone product including viable osteogenic cells
A bone implant comprising cancellous bone that is essentially free of blood cells, and which has been treated with at least one loosening agent, such as collagenase or a digestive enzyme, for a time and at a concentration to loosen the osteogenic cells in the cancellous bone matrix. The osteogenic cells in the matrix are viable cells. The treatment of the cancellous bone with at least one loosening agent enables the osteogenic cells to be more available for carrying out their osteogenic function and to provide for an increased rate of bone formation. Such implant also may include demineralized bone, such as demineralized cortical bone, which enhances the bone regenerative capacity of the cancellous bone.
US10898606B2 Self-fusing low density silicone
An adhesive free self-fusing material being either of open or closed cell polymer (silicone) based material that can be used to create a permanent elastic band for compression and support dressings. The proprietary polymer material upon contact with itself, initiates a “room temperature” reaction of self-vulcanization with the contact surfaces of itself. This eliminates the need for any adhesives which some patients experience negative reactions. In an example embodiment, the material comprises Vinyl stopped polydimethyl siloxane, amorphous silica, and dimethylpolysiloxane.
US10898604B2 Air treatment system
An apparatus for treating air includes a housing with an air inlet and an air outlet, the housing enclosing an air treatment zone and an ozone removal zone, wherein the ozone removal zone is positioned downstream of the air treatment zone with respect to a flow direction of the air being treated, an ozone generator in the air treatment zone configured to generate ozone from the air, wherein the ozone generated by the ozone generator treats the air in the air treatment zone, catalyst in the ozone removal zone that removes at least a portion of the ozone generated the ozone generator, a particle matter (PM) filter positioned between the air treatment zone and the ozone removal zone, wherein the ozone generated by the ozone generator treats the PM filter, and an air mover positioned near the air outlet configured to draw the air through the air inlet.
US10898602B2 Alcohol vapor deodorization system
A system that deodorizes gear, padding, or other apparel by killing the bacteria that cause odor. Articles to be deodorized are placed within a re-sealable airtight bag along with highly pure anhydrous ethanol. As the ethanol vaporizes, the gaseous ethanol readily dissolves within the aqueous environment that envelops the bacteria. Ethanol levels within this moisture gradually increase and eventually become bactericidal.
US10898600B2 Disinfecting method and disinfecting apparatus
A disinfecting method includes irradiating fungi or bacteria with light including violet light having a light emission peak with (i) a full width at half maximum of at most 20 nm and (ii) a peak wavelength included in a range of from 380 nm to 410 nm, inclusive.
US10898599B2 Radio frequency treatment to phytosanitize wood packaging materials used in international shipping
A method for treating wood packaging materials using Radio Frequency heating includes the steps of heating wood packaging materials using RF heating and applying a pressure before the heating or incrementally applying a pressure during the heating until a temperature of the wood packaging materials reaches at least 60° C. and that temperature is maintained for at least 1 minute.
US10898594B2 PAMAM dendrimer based CEST imaging agents and uses thereof
PAMAM dendrimer based CEST imaging agents, pharmaceutical compositions comprising the same and methods of uses thereof are disclosed.
US10898591B2 Compositions and methods for assessing eye vasculature
Compositions and methods for assessing blood vessels and organs of the body are disclosed herein, specifically methods for assessing the vasculature of the eye.
US10898589B2 Nucleic acid comprising or coding for a histone stem-loop and a poly(A) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein
The present disclosure concerns a nucleic acid sequence, comprising or coding for a coding region, encoding at least one peptide or protein comprising a therapeutic protein or a fragment, variant or derivative thereof, at least one histone stem-loop and a poly(A) sequence or a polyadenylation signal. The present disclosure further concerns a method for increasing the expression of a peptide or protein comprising a therapeutic protein or a fragment, variant or derivative thereof, using the nucleic acid comprising or coding for a histone stem-loop and a poly(A) sequence or a polyadenylation signal.
US10898585B2 Gene therapy for AADC deficiency
The present invention is directed to compositions and methods for treating aromatic L-amino acid decarboxylase (AADC) deficiency. This invention includes a method of treating AADC deficiency in a pediatric subject, comprising the steps of: (a) providing a pharmaceutical formulation comprising an rAAV2-hAADC vector, (b) stereotactically delivering the pharmaceutical formulation to at least one target site in the brain of the subject in a dose of an amount at least about 1.8×1011 vg; wherein delivering the pharmaceutical formulation to the brain is optionally by frameless stereotaxy, and optionally wherein the dose is an amount of at least about 2.4×1011 vg and in some embodiments wherein the pharmaceutical formulation comprises a rAAV2-hAADC vector concentration of about 5.7×1011 vg/mL. This invention is also directed to methods for treating aromatic L-amino acid decarboxylase (AADC) deficiency, wherein the method optionally further comprises the step of administering a therapeutically effective dose of dopamine-antagonist to the subject such as risperidone. This invention is also directed to methods for treating aromatic L-amino acid decarboxylase (AADC) deficiency, wherein the method optionally comprises providing a pharmaceutical formulation comprising an rAAV2-hAADC vector, and empty capsids.
US10898584B2 Modified RNA with decreased immunostimulatory properties
The present invention provides a method for providing modified mRNAs of reduced immunogenicity and/or immunostimulatory capacity for use in protein replacement therapy. The invention further provides modified mRNAs and pharmaceutical compositions comprising the modified mRNAs according to the invention for use in protein replacement therapy.
US10898579B2 Conjugates of cysteine engineered antibodies
The invention relates to novel cell-binding agent-cytotoxic agent conjugates, wherein the cell-binding agent (CBA) is covalently linked to the cytotoxic agent through an engineered Cys, such as an engineered Cys in the heavy chain CH3 domain, at a position corresponds to the EU/OU numbering position 442 (or C442) on an antibody CBA. The invention also provides methods of preparing the conjugates of the present invention. The invention further provides composition and methods useful for inhibiting abnormal cell growth or treating a proliferative disorder in a mammal using the conjugates of the invention.
US10898572B2 Stable protein-containing preparation containing argininamide or analogous compound thereof
Addition of argininamide or valinamide to a highly concentrated antibody solution was found to lead to remarkable stabilization, in particular, stabilization against photostress.
US10898568B2 Modular antigen transportation molecules and uses thereof in animals
The present invention relates to (isolated) recombinant proteins, also referred to as improved MAT (iMAT) molecules, comprising at least one translocation module, at least one targeting module and at least one antigen module, wherein at least one cysteine residue is substituted with a different amino acid residue. Such iMAT molecules are useful specifically as vaccines, e.g. for therapy and/or prevention of allergies and/or infectious diseases and/or prevention of transmission of infectious diseases in animals, more preferably ruminants, pigs, dogs and/or cats, but excluding equines. The present invention further relates to nucleic acids encoding such iMAT molecules, corresponding vectors and primary cells or cell lines.
US10898565B2 Compositions, methods and uses for dengue virus serotype-4 constructs
Embodiments herein report compositions, methods and uses for dengue-4 (DENV-4) virus constructs. Some embodiments concern a composition that includes, but is not limited to, DENV-4 virus constructs alone or in combination with other constructs, can be used in a vaccine composition to induce an immune response in a subject. In certain embodiments, compositions can include constructs of more than one serotypes of dengue virus, such as dengue-1 virus, dengue-2 virus, or dengue-3 virus in combination with DENV-4 virus constructs disclosed herein. In other embodiments, DENV-4 constructs disclosed herein can be combined in a composition with other flavivirus constructs to generate a vaccine against more than one flavivirus. Other embodiments provide methods and uses for DENV-4 virus constructs in vaccine compositions that when administered to a subject induce an immune response in the subject against DENV-4 that is improved by modified constructs compared to other vaccine compositions.