最新美国发明专利
Document Document Title
US10894125B2 Infusion devices and related rescue detection methods
Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device to deliver fluid to a body of a user involves obtaining measurement values for a physiological condition influenced by the fluid, autonomously operating the infusion device to deliver the fluid based at least in part on the measurement values, and detecting a nonactionable condition based on the measurement values. In response to detecting the nonactionable condition, delivery of the fluid is limited while maintaining autonomous operation of the infusion device. In one exemplary embodiment, the nonactionable condition is a rescue condition indicative of the user having consumed fast-acting carbohydrates, and thus insulin delivery may be automatically limited in response to detecting the rescue carbohydrate consumption.
US10894123B2 Fluid delivery system
The invention generally provides a fluid delivery system comprising: a reservoir (7); a pumping chamber (8) having a volume, an inlet valve (48), an outlet valve (49) and a membrane (47); an actuator (20); and a drive member (21). The inlet valve and the outlet valve each comprise a passive normally closed one-way check valve. The inlet valve provides selective fluid communication between the pumping chamber volume and the reservoir. Fluid in the reservoir is at substantially ambient pressure. The drive member is operatively coupled to the pumping chamber membrane. Energising the actuator moves the drive member in reciprocating motion and thereby displaces the membrane to change the pumping chamber volume between a minimum volume and a maximum volume. The pumping chamber volume is held at a pressure above the ambient pressure in the reservoir when the actuator is at rest.
US10894114B2 Driveline bone anchors and methods of use
Systems, methods, and devices for securing a driveline to a bone are disclosed herein. The driveline can connect an external controller to an implantable blood pump. The bone anchor can include a driveline capture portion. The driveline capture portion can receive the driveline and fix a position of the driveline with respect to the driveline capture portion. The driveline capture portion includes: a driveline receiver that can receive the driveline; and a driveline anchor that can engage the driveline to fix the position of the driveline with respect to the driveline receiver. The bone anchor can include a bone capture portion. The bone capture portion can engage a bone and fix a position of the bone with respect to the bone capture portion.
US10894112B2 Substrate having an electron donating surface with metal particles comprising palladium on said surface
There is disclosed a substrate with an electron donating surface, characterized in having metal particles on said surface, said metal particles comprising palladium and at least one metal selected from the group consisting of gold, ruthenium, rhodium, osmium, iridium, and platinum, wherein the amount of said metal particles is from about 0.001 to about 8 μg/cm2. Examples of coated objects include contact lenses, pacemakers, pacemaker electrodes, stents, dental implants, rupture nets, rupture mesh, blood centrifuge equipment, surgical instruments, gloves, blood bags, artificial heart valves, central venous catheters, peripheral venous catheters, vascular ports, haemodialysis equipment, peritoneal dialysis equipment, plasmapheresis devices, inhalation drug delivery devices, vascular grafts, arterial grafts, cardiac assist devices, wound dressings, intermittent catheters, ECG electrodes, peripheral stents, bone replacing implants, orthopaedic implants, orthopaedic devices, tissue replacing implants, intraocular lenses, sutures, needles, drug delivery devices, endotracheal tubes, shunts, drains, suction devices, hearing aid devices, urethral medical devices, and artificial blood vessels.
US10894110B2 Developable hyaluronic acid microspherical embolic agent, preparation method and use thereof
A developable hyaluronic acid microspherical embolic agent includes a hyaluronic acid and an X-ray opaque contrast material; wherein the hyaluronic acid is a modified hyaluronic acid, wherein a modifying method for preparing the modified hyaluronic acid is cross-linking, grafting, esterification, or recombination, and is preferably cross-linking.
US10894108B2 Antimicrobial floor mat
Disclosed herein are devices, designs, and methods of using a device for sanitizing feet, shoes, or other surfaces in contact with the floor. The apparatus is capable of detecting the presence of a user and automatically spraying the feet of a user with a sanitizing fluid. Fluid is expelled through an elevated grate, which allows the user to stand on an elevated grate and have their feet sanitized without exposing their feet to a dirty pool of liquid.
US10894106B1 Moving tunnel sanitizer
A moving tunnel sanitizer includes a frame forming a tunnel with a tunnel opening through the frame. A right wall supports a right side of the frame. A left wall supports a left side of the frame. A right front wheel and a right rear wheel support the right wall. A left front wheel and a left rear wheel supports the left wall. A top member makes a rigid connection between the right wall to the left wall. Nozzles are mounted on the tunnel on the right wall and on the left wall. A fluid tank stores a sanitizing fluid. The fluid tank is connected to the nozzles by fluid tubing. A left motor and a right motor are drive motors. The left motor drives either the front left wheel or the rear left wheel. The right motor drives the front left wheel or the front right wheel.
US10894105B2 Air pollution abatement and crop growth stimulation technology
A system and method of abating air pollution and stimulating crop growth. A reagent is introduced to a crop canopy to neutralize air pollutants within said canopy, wherein the reagent induces an oxidation-reduction chemical reaction with the air pollution present throughout the acreage of crops, and by means of the reaction effectually neutralizes the harmful effects of the air pollutants on the crops. The reagent is diluted using a venturi valve or other means. The flow rate of said reagent is regulated using an electronic control unit, based on data collected from at least one type of sensor in the canopy that is in communication with the control unit.
US10894104B1 LED lighting device for sterilizing surface or space
Disclosed herein is a light emitting diode (LED) lighting device for sterilizing a surface or a space capable of effectively performing short-distance sterilization or long-distance sterilization. The device includes: a body including an inner transparent tube and an outer transparent tube in a double-tube type, the inner transparent tube forming a vertical ventilation hole and the outer transparent tube being spaced apart from the inner transparent tube at a predetermined distance; a substrate provided in a space formed by the inner transparent tube and the outer transparent tube; and a first light emitting element and a second light emitting element provided on an outer surface of the substrate. The first light emitting element emits visible light having a first wavelength of 405 nm, and the second light emitting element emits short-wavelength visible light having a second wavelength in the range of 400 to 450 nm.
US10894096B2 3,6,9, 15-tetraaza-bicyclo [9.3.1]pentadeca-1(14), 11(15), 12-triene based compounds and their application as ligands of essential metal ion based MRI and 52MN based PET contrast agents
A compound of the following general formula (I), and isomers, physiologically acceptable salts, and complexes thereof, for use as a contrast agent in diagnostic imaging:
US10894090B2 Antibody drug conjugates (ADC) that bind to 191P4D12 proteins
Antibody drug conjugates (ADC's) that bind to 191P4D12 protein and variants thereof are described herein. 191P4D12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.
US10894089B2 Long-acting insulin or insulin analogue conjugate
The present invention relates to insulin and/or an insulin analogue conjugate, and a use thereof, wherein the insulin and/or insulin analogue have improved in vivo durability and stability by linking the same with an Fc region of immunoglobulin. The insulin and/or an insulin analogue conjugate of the present invention show an in vivo activity similar to that of insulin. In addition, the insulin and/or insulin analogue conjugate of the present invention are long-acting formulations of insulin and/or the analogue thereof, in which serum half-life is remarkably increased, and therefore, the present invention provides remarkable insulin and/or an insulin analogue conjugate, which do not induce hypoglycemia, a drawback of insulin treatment.
US10894088B2 BSH complex for boron neutron capture therapy
The present invention provides: a complex of a mercaptoundecahydrodecaborate (BSH) and a peptide, the complex for boron neutron capture therapy (BNCT); a method for producing the complex; and a cancer therapy using the complex.
US10894087B2 Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
Among other aspects, provided herein are multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds. Methods of preparing such conjugates as well as methods of administering the conjugates are also provided. Upon administration to a patient, release of the cabazitaxel-based compound is achieved.
US10894086B2 Functional hydrated hyaluronic acid and method for producing coated lactic acid bacteria having excellent intestinal mucoadhesive ability and selective antagonistic action using same
The present invention relates to a functional hydrated hyaluronic acid and a method for producing 5th generation coated lactic acid bacteria having excellent intestinal mucoadhesive ability and a selective antagonism using the same and, more specifically, to a functional hydrated hyaluronic acid in which components fermented by lactic acid bacteria are captured in hyaluronic acid, which is a natural polymer substance, and a method for producing coated lactic acid bacteria using the same. The quadruply coated lactic acid bacteria coated using the functional hydrated hyaluronic acid according to the present invention is quadruply coated with a water-soluble polymer, a functional hydrated hyaluronic acid, a coating agent having porous particles, and a protein, thereby producing an excellent intestinal mucoadhesive ability, exhibiting an antibacterial action against deleterious bacteria in the intestines, and promoting growth of beneficial bacteria in the intestines.
US10894084B2 Metal-assisted and microwave-accelerated decrystallization
In this study, we demonstrated a unique application of our Metal-Assisted and Microwave-Accelerated Decrystallization (MAMAD) technique for the de-crystallization of uric acid crystals, which causes gout in humans when monosodium urate crystals accumulate in the synovial fluid found in the joints of bones. Given the shortcomings of the existing treatments for gout, we investigated whether the MAMAD technique can offer an alternative solution to the treatment of gout. Our technique is based on the use of metal nanoparticles (i.e., gold colloids) with low microwave heating to accelerate the de-crystallization process. In this regard, we employed a two-step process; (i) crystallization of uric acid on glass slides, which act as a solid platform to mimic a bone, (ii) de-crystallization of uric acid crystals on glass slides with the addition of gold colloids and low power microwave heating, which act as “nano-bullets” when microwave heated in a solution. We observed that the size and number of the uric acid crystals were reduced by >60% within 10 minutes of low power microwave heating. In addition, the use of gold colloids without microwave heating (i.e. control experiment) did not result in the de-crystallization of the uric acid crystals, which proves the utility of our MAMAD technique in the de-crystallization of uric acid.
US10894083B2 Stable aqueous anti-vascular endothelial growth factor (VEGF) antibody formulation
The present invention relates to the field of pharmaceutical formulations of antibodies. Specifically, the present invention relates to a stable liquid antibody formulation and its pharmaceutical preparation and use. This invention is exemplified by an aqueous formulation of an anti-vascular endothelial growth factor (VEGF) antibody.
US10894081B2 Recombinant bivalent inactivated vaccine against foot-and-mouth disease virus, preparation method and use thereof
The present disclosure relates to a foot-and-mouth disease virus vaccine composition, especially a recombinant bivalent vaccine composition against type O and type A foot-and-mouth disease viruses. The present disclosure further relates to a method for preparing the foot-and-mouth disease virus vaccine composition, and a use of the foot-and-mouth disease virus vaccine composition in preparing medicines for preventing and/or controlling foot-and-mouth disease in animals.
US10894080B2 Transgenic VERO-CD4/CCR5 cell line
The present relation relates to a transgenic Vero cell line expressing CD4 and CCR5. The present invention encompasses the preparation and purification of immunogenic compositions which are formulated into the vaccines of the present invention.
US10894079B2 Chromatography based purification strategies for viruses
The present invention provides purification strategies for sterically demanding, i.e. large and pleomorphic, infectious virus particles or VLPs derived therefrom, preferably having a measles virus scaffold to yield fractions or compositions with a significantly reduced content of contaminating host cell DNA and a reduced content of further process-related impurities. Further provided are methods of propagating and purifying infectious virus particles having a measles virus scaffold suitable to provide a preparation having a strongly reduced content of contaminating host cell DNA and a reduced content of further process-related impurities for immunogenic or anti-tumor purposes. In addition, immunogenic and vaccine compositions based on the above methods are provided. Finally, there are provided immunogenic or vaccine compositions produced by the disclosed methods, which are suitable for use in immunogenic or prophylactic vaccination treatment of a subject in need thereof.
US10894078B2 HIV vaccines comprising one or more population episensus antigens
Provided herein are HIV-1 vaccines comprising a carrier and a population episensus antigen determined using the EpiGraph approach. Also provided are HIV-1 vaccines comprising a carrier, a population episensus antigen, and a tailored antigen. Also provided are methods of designing and producing an HIV-1 vaccine for a subject comprising designing vaccine antigens to optimally cover the diversity within a geographic area using an antigen amino acid sequence generated using the EpiGraph approach, and producing said designed vaccine antigen. Also provided are methods of inducing an effector memory T cell response comprising designing the one or more EpiGraph amino acid sequences, producing a vaccine comprising the one or more EpiGraph amino acid sequences and a vector, and administering the vaccine to a subject. Further provided are methods of treating HIV-1 in a subject comprising administering an effective amount of the described HIV-1 vaccines to the subject in need thereof.
US10894075B2 Gla domains as targeting agents
The disclosure relates to the recombinant Gla domain proteins and their use targeting phosphatidylserine (PtdS) moieties on the surface of cells, particularly those expressing elevated levels of PtdS, such as cells undergoing apoptosis. These proteins can be linked to both diagnostic and therapeutic payloads, thereby permitting identification and treatment of cells expression elevated PtdS.
US10894069B2 Topical antiviral formulations and methods of using the same
Antiviral pharmaceutical compositions comprising one or more cannabinoid compounds in the form of lip-balms, creams and ointments. A specific embodiment provides a topical composition formulated as a lip-balm.
US10894067B2 Genome stability enhancer
Disclosed is a genome stability enhancer comprising, as an active ingredient, at least one member selected from the group consisting of enzyme-treated royal jelly, gnetum or its extract, and gnetin C.
US10894063B2 Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
US10894055B2 Pharmaceutical compositions, methods of making pharmaceutical compositions, and kits comprising 2-{[3,5-bis(trifluoromethyl)phenyl]carbamoyl}4-chlorophenyl dihydrogen phosphate
Provided are novel formulations of 2-{[3,5-bis(trifluoromethyl)phenyl]carbamoyl}-4-chlorophenyl dihydrogen phosphate as described below and uses thereof.
US10894054B2 FXR agonist compositions for combination therapy
The present application relates to a pharmaceutical composition comprising a combination of an FXR agonist and at least one additional therapeutic agent that lowers the glucose level in the blood, stimulates insulin secretion, and/or increases insulin sensitivity. The present application relates to use of the pharmaceutical composition for the treatment or prevention of a FXR mediated disease or condition, such as NAFLD and NASH, a disease or condition related to an elevated level of glucose in the blood, decreased secretion of insulin, and/or decreased insulin sensitivity such as hyperglycemia, diabetes, obesity, and insulin resistance, or for lowering the glucose level in the blood, stimulating insulin secretion, and/or increasing insulin sensitivity.
US10894053B2 Pharmaceutical compositions comprising meloxicam
Disclosed herein are compositions comprising an NSAID such as meloxicam and/or rizatriptan in combination with a cyclodextrin and/or a carbonate or a bicarbonate. These compositions may be orally administered, for example, to improve the bioavailability or pharmacokinetics of the NSAID for the treatment of pain such as migraine, arthritis, and other conditions. Also disclosed herein are methods of treating pain, such as migraine, comprising administering meloxicam and rizatriptan to a human being suffering from pain, such as migraine. For migraine, these methods may be particularly useful when the meloxicam and rizatriptan are administered while the human being is suffering from an acute attack of migraine pain or migraine aura. In some embodiments, the combination of meloxicam and rizatriptan may be administered in a manner that results in a Tmax of meloxicam of 3 hours or less.
US10894052B2 Heterocyclic inhibitors of ATR kinase
The present disclosure relates to heterocyclic compounds and methods which inhibit ATR kinase to treat or prevent cancer.
US10894051B2 Method of treating metastatic cancer in a subject
A method of treating metastatic cancer in a subject suffering from metastatic cancer includes administering an effective amount of a compound having a structure of Formula I, in particular a compound having a structure of Formula II, to the subject. Also, a method of inhibiting metastasis of cancer cells includes contacting the cancer cells with an effective amount of a compound having the structure of Formula I, in particular a compound having the structure of Formula II.
US10894046B2 Bupropion as a modulator of drug activity
Dosage forms, drug delivery systems, and methods related to sustained release of dextromethorphan or improved therapeutic effects are disclosed. Typically, bupropion or a related compound is orally administered to a human being to be treated with, or being treated with, dextromethorphan.
US10894039B2 Amlodipine formulations
Provided herein are stable amlodipine oral liquid formulations. Also provided herein are methods of using amlodipine oral liquid formulations for the treatment of certain diseases including hypertension and Coronary Artery Disease (CAD).
US10894029B2 Neuroprotective compositions and their use
Disclosed are compositions containing not less than 10% w/w of oroxylin A, not less than 10% w/w of baicalein and not less than 2% w/w of chrysin for use in the therapeutic management of memory impairment and cognitive dysfunction. More specifically, the invention discloses the use of abovementioned compositions for the management of cognitive impairment induced by chemotherapy and hyperglycemia.
US10894027B2 Sickle cell disease treatment utilizing omega-3 fatty acids
Described herein are compositions including at least one omega-3 fatty acid (either in the triglyceride, ester or free fatty acid ester form) and at least one surface active agent; wherein the compositions form micelles when in contact with an aqueous medium. Also provided are methods of administering to a subject a composition including at least one omega-3 fatty acid (either in the triglyceride, ester or free fatty acid ester form) and at least one surface active agent, wherein the compositions form micelles when in contact with an aqueous medium, and the bioavailability of the omega-3 fatty acid is substantially independent of a food effect. The compositions are useful for treating certain disease states which may include (1) malabsorption syndromes, (2) primary sclerosing cholangitis (PSC), (3) non-alcoholic fatty liver disease (NAFLD), (4) sickle cell disease (SCD), (5) age-related macular degeneration (AMD), and (6) neurodegenerative disease, including, Parkinson's Disease (PD), Alzheimer's Disease (AD), Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig's Disease), Epilepsy, Bi-polar Syndrome, traumatic brain injury, peripheral neuropathy, and Multiple Sclerosis (MS). Described are also various dosage forms for administering the compositions and use of the compositions in functional foods. Provided herein are also kits with instructions for their administration.
US10894021B2 Compositions of xanthorrhizol and tocochromanol (tocotrienol), and methods of use
A dietary supplement composition provided synergistic effects of xanthorrhizol and tocotrienol on malignancies. A blend of xanthorrhizol and delta tocotrienol achieved 69% growth suppression of melanoma, exceeding the sum of individual effects. In prostate cancer, 90% growth suppression was achieved by a blend of xanthorrhizol and delta tocotrienol; however, the same 90% of growth suppression was achieved by 3-fold xanthorrhizol and 1.8-fold delta tocotrienol respectively, which indicated synergistic impact of the two agents. Mechanisms of action for the anticancer property showed synergism of xanthorrhizol and tocotrienol-mediated cancer growth suppression was attributed to cell cycle arrest, at the G1 phase of cell cycle, and apoptosis. This novel dietary supplement combination of xanthorrhizol to tocotrienol (1:1 to 10:1) may provide benefits to individuals consuming it on a regular or periodic basis.
US10894019B2 Drug delivery system and method for targeting cancer stem cells
Systems and methods for targeting specific cancer cell subpopulations present in tumor tissue are described. A system can include a first component for specifically targeting cancer stem cells and a second component for specifically targeting differentiated cancer cells. A system can include a drug conjugated to small (e.g., 5-20 nm) nanoparticles, e.g., polyhedral oligomeric silsequioxane nanoparticles. The small nanoparticles can be preferentially taken up by cancer stem cells via macropinocytosis and can release a toxic payload within the cancer stem cells without triggering the efflux pump. A system can include a second component that targets differentiated cancer cells, e.g., a free drug or a drug encapsulated in nanoparticles.
US10894017B1 Rapidly disintegrating solid oral dosage forms containing dasatinib
The instant application relates to the field of pharmaceutical compositions comprising dasatinb. Furthermore, the instant application relates to a method of treating proliferative disorders in a patient in need thereof, comprising administering a therapeutically effective amount of said compositions.
US10894014B2 Orodispersible tablet containing Estetrol
The invention provides an orodispersible solid pharmaceutical dosage unit having a weight between 30 and 1,000 mg, said dosage unit containing at least 100 μg of an estetrol component selected from estetrol, estetrol esters and combinations thereof; wherein the solid dosage unit can be obtained by a process that comprises: providing a loading liquid comprising organic solvent; estetrol component and optionally one or more other pharmaceutically acceptable ingredients; mixing 1 part by weight of the loading liquid with 0.5-20 parts by weight of carrier particles to produce wet particles; removing organic solvent from the wet particles to produce loaded particles; optionally mixing the loaded particles with one or more tabletting excipients; and forming the loaded particles or the mixture of the loaded particles and the one or more tabletting excipients into a solid dosage unit. The solid dosage unit is easy to manufacture and perfectly suited for sublingual, buccal or sublabial administration.
US10894012B1 Pharmaceutical compositions and methods of using the same
Novel pharmaceutical compositions including cocaine hydrochloride and methods of treating patients using those pharmaceutical compositions are described.
US10894010B2 Cosmetic compositions which are homogenous in the bulk and capable of forming a multilayer structure after application to a keratinous material
Cosmetic compositions capable of forming a multilayer structure after application to a keratinous material are provided, as well as methods of applying such compositions to keratinous material. Certain compositions comprise: Component A which comprises about 0.01% to 50% by weight with respect to the total weight of the composition of at least one silicone- and/or hydrocarbon-containing film forming agent having at least one glass transition temperature which is lower than 60° C.; Component B which comprises about 0.01% to 90% by weight with respect to the total weight of the composition of one or more silicone compounds having a viscosity of greater than about 10 million cSt; and an inorganic pigment, skin active agent, skin adjuvant, or UV filter; wherein the weight ratio of the silicone- and/or hydrocarbon-containing film forming agent(s) in Component A to silicone compound(s) in Component B of about 1:1.5 to about 1:100.
US10894009B2 Topical agent for transdermal administration
The present invention aims to provide a cyclosporine external preparation showing improved transdermal absorbability of cyclosporine. The present invention provides an external preparation containing cyclosporine and a ketone.
US10894007B2 Hair care composition with encapsulated moisturizers and method to deliver extended moisture release to the hair
Methods and composition are provided for a hair care composition that comprises at least one encapsulated moisturizing ingredient. The composition comprises at least one surfactant, at least one capsule that encapsulates a benefit agent, and a carrier. The composition may further comprise additional components, which may be a function of the type of hair care composition. A method of using a hair care composition that comprises at least one encapsulated moisturizing ingredient is also provided.
US10894006B2 Nanoparticles for the encapsulation of compounds, preparation thereof and use of same
The present invention relates to nanoparticles for encapsulating compounds, the preparation and uses thereof, comprising a casein matrix, a basic amino acid and a metal selected from a divalent metal, a trivalent metal and combinations thereof. Said nanoparticles can encapsulate a water soluble or fat soluble biologically active compound. The invention is applicable in the food, pharmaceutical and cosmetic sectors and in the nanotechnology sector.
US10894005B2 Detergent product and method for making same
A hair care product containing one or more hair care active agents is provided.
US10894002B2 Systems, devices, and/or methods for managing medicaments
Certain exemplary embodiments can provide a device, which can comprise a pill reservoir, a first layer, and a chamber. The first layer comprises an inclined entry passage open to the pill reservoir and an exit passage open to a dispense passage. A portion of the chamber layer can travel linearly in close communication within a tubular shaped portion of the first layer.
US10893999B2 Multi-part device for controlled cardiopulmonary resuscitation during cardiac arrest
The invention relates to a device for controlled cardiopulmonary resuscitation, which allows the user to reanimate a human body quickly and simply during a cardiac arrest. The geometric dimensions of the claimed device are comparatively small and lie between approximately 10 and 25 cm in diameter and approximately 6 and 12 cm in height. During use, a force K is exerted onto a first force transmission means, a clearly audible signal being generated when a maximum adjustable force exertion Kmax is reached. Said clearly audible signal is primarily generated by the interaction of oscillatory elements of said device.
US10893997B2 Rehabilitation mechanism for patients confined to bed
A rehabilitation mechanism rehabilitates the joints, muscles, and tendons of the legs of a bedridden patient in an automated manner according to a plan. A knee module can be operatively connected to the knee joint of the patient. A control module controls rehabilitation movements by way of the knee module. The knee module is a module to be arranged above the patient and the mattress, which module is supported directly or indirectly on a bed or the mattress frame, and includes a knee prosthesis which receives a knee joint of the patient, a connection element connected to the knee prosthesis, an extension arm to which the connection element is secured, and a mechanism to be actuated by the control module and which introduces a defined force into the knee prosthesis via the extension arm and the connection element to carry out rehabilitation movements according to a plan.
US10893994B2 Apparatus for assisting toilet user in standing up
An apparatus for aiding a user of a toilet in standing up includes a structure where the user can sit, and includes a movable seat movably mounted to the toilet; and a seat actuator arranged adjacent to the toilet and actuating the movable seat to move having at least one of lifting movement and pivoting movement.
US10893992B2 Bed device
A bed device includes: an operation section that receives an operation input; a controller that controls a movement of the bed in accordance with the operation input; a detector that detects a position of a patient on the bed; and, a limitation table that stores a limitation area set on the bed in association with a limitation content, wherein when the position of the patient detected by the detector is included in the limitation area, the limitation content is read out from the limitation table so as to control the controller in accordance with the limitation content. With this configuration, it is possible to provide a higher safety bed device which can not only notify the danger based on the bed movement but also limit the movement of the bed in accordance with the status of the patient or the bed device.
US10893982B2 Perforated, layered wound treatment material
Wound treatment materials can have at least two perforated biomatrix layers which are interconnected. Methods for preparing such wound treatment materials include the application of adhesives. Treatment of exuding wounds, and vacuum-assisted wound treatment therapy, can be carried out with the wound treatment materials.
US10893978B2 Vitreous cutter pneumatic driver
Systems and methods for driving the cutter of a vitrectomy handpiece using a substantially hermetically sealed system having a pneumatic pump for alternatively creating both positive pressure for pushing a first side of a diaphragm in the vitreous cutter and pulling negative pressure to pull the other side of the diagram, and vice versa.
US10893974B2 Base plate of an ostomy appliance
A base plate of an ostomy appliance includes a film, an adhesive disposed on a proximal surface of the film, an annular ring connected to the distal surface of the film, and a release liner removably attached to the adhesive. A stoma-receiving through-going hole is formed through the film and the adhesive and the release liner. A first section of the base plate extends radially from the stoma-receiving through-going hole to a second section of the base plate, and the second section extends radially from the first section to an outermost perimeter edge of the base plate. The base plate is formed to have a heat-set curvature such that a proximal side of the second section is convex and a distal side of the second section is concave relative to the annular ring.
US10893973B1 Ostomy bag cleaning apparatus
The present invention relates to an ostomy bag cleaning apparatus. The apparatus comprises support structure. The support structure comprises a support bar; a plurality of legs configured at one end of the support bar for supporting the support bar; and a mounting bracket fitted at an operative top end of the support bar. The apparatus further comprises a funnel supported at an operative top end of the support structure, wherein a user evacuates an ostomy bag, the funnel being mounted on the mounting bracket; a first conduit extending from the funnel, wherein the first conduit is a drain conduit for draining out the contents of ostomy bag; a second conduit routed into the funnel for allowing a user to wash the ostomy bag in the funnel; and a valve for regulating a supply of water to the second conduit.
US10893971B2 External nasal dilator with multiple discrete dilation points
An external nasal dilator comprises resilient and engagement elements, and includes end regions adapted to engage tissues overlaying and adjacent first and second nasal passages of a human nose. Each end region includes a plurality of resilient spring finger components separated therebetween by engagement element tab extensions. The end regions are further adapted to extend around the anatomical depression formed by the alar crease adjacent each nostril. When in use the dilator stabilizes or expands said tissues and prevents or inhibits the nasal outer walls from drawing inward during breathing.
US10893969B2 Rear sheet adjustment assembly of neck collar
A rear sheet adjustment assembly of neck collar is provided, including a nape base and a support sheet. The nape base includes a main body, at least one stopper, a positioning member and a plurality of openings. The at least one stopper is connected with the main body and defines an inserting space therebetween. The positioning member is disposed on the main body. The positioning member has a first combination portion. The support sheet is adapted for supporting a nape of a neck and movably inserted within the inserting space. The support sheet has a plurality of second combination portions, and each of the second combination portions is adjustably engageable with the first combination portion.
US10893963B2 Stent delivery with expansion assisting delivery wire
A method for implanting a stent by providing an implantation system including a catheter, an expandable element, and a delivery wire, moving a first portion of the expandable element to exit the catheter, and maintaining a second portion of the expandable element within the catheter to establish a partially implanted configuration. Then moving the delivery wire independent of the expandable element in the partially implanted configuration, and enlarging a circumference of the expandable element in response to the moving the delivery wire.
US10893962B2 Growth stent and valve for congenital narrowings
A growth stent and valve and methods for making and using the same. The growth stent and valve may be delivered to treat early stage congenital lesions, while expanding to adult vessel diameters. In selected embodiments, the growth stent and valve can comprise a frame and may have a covering on some portion to prevent blood flow through a wall of the frame. The growth stent and valve advantageously can maintain radial strength across an entire range of diameters necessary to treat a narrowed lesion from birth and childhood through adulthood as the vessels grow over the lifetime of a patient.
US10893958B2 Multi-articulated link knee joint
A multi-articulated link knee joint includes: a knee unit in which an upper link member is structured to rotate relative to a lower link member by a multi-articulated link mechanism including a plurality of link members including the upper link member and the lower link member; a driven member to move in accordance with the rotation of the upper link member; a position detector for detecting the position of the driven member, the position detector provided at the lower link member; and an angle detector for obtaining the bending angle of the knee unit from the position of the driven member.
US10893957B2 Mechanical grasping device
A mechanical grasping device where each of the segments of the finger assemblies, are individually sizeable. This allows for both a proportionately scalable grasping device as well as individual customization of geometric configurations tailored to specific use patterns. The mechanical grasping device is crushable since it has flexible and pivotable connections between digits along its length and width. It has a hollow member construction that imparts a strong lightweight design. It is modular so individual parts can be replaced for quick repair. From an aesthetics point, it is visually pleasing and can be offered in different colors, and with custom digit sleeves for specific applications. Finger assemblies can be operated individually or in groups via pairs of cables which allow operation in either voluntary open or voluntary closed modes of control. The flexible construction allows gripping of irregularly shaped objects and deforms before failing giving indication of overload prior to failure.
US10893955B2 Non-symmetrical insert sensing system and method therefor
An orthopedic system to monitor a parameter related to the muscular-skeletal system is disclosed. The orthopedic system includes electronic circuitry, at least one sensor, and a computer to receive measurement data in real-time. The orthopedic system comprises a first plurality of shims of a first type, a second plurality of a second type, a measurement module, and the computer. The measurement module houses the electronic circuitry and at least one sensor. The measurement module is adapted to be used with the first plurality of shims and the second plurality of shims. The measurement module has a medial surface that differs from a lateral surface by shape, size, or contour.
US10893953B2 Side pocket spinal fusion cage
A spinal implant is provided including an upper surface, a lower surface, a front surface and a back surface, two side surfaces extending between the upper surface and the lower surface, the two side surfaces extending between the front surface and the back surface and an opening positioned closer to the back surface than the front surface. The opening is provided to contain graft material that spans between a cortical rim of the upper vertebral body and the cortical rim of the lower vertebral body. The method includes packing the opening with graft material, wherein the graft material spans between the decorticated cortical rim of the upper vertebral body and the decorticated cortical rim of the lower vertebral body.
US10893950B2 Multi-piece intervertebral implants
Intervertebral implants for implanting into an intervertebral space are provided. The implants can comprise one or more layers that are operably attached to one another. An implant can comprise a first layer having a first mating surface that mates with a second mating surface of a second layer. The first mating surface and the second mating surface can have features that allow them to complement each other. The implants can include one or more bore holes for receiving a fixation member. The bore holes can be horizontal, vertical or diagonal. In some cases, the bore holes will be blind bore holes.
US10893948B2 Rotary arc patella articulating geometry
Disclosed herein are patellar implants and methods to prepare bone for receiving the same. The patellar implant may include an articulating surface with an elliptically shaped median ridge. The anterior surface of the patellar implant may have a non-planar surface to engage with a resected natural patella. The non-planar surface may allow for varying thickness of the patellar implant. The patellar implant may include dual attachment features to secure patellar implant to a resected patella by onlay and inlay techniques. A method for attaching a patellar implant to a patella may include onlay and inlay techniques and may further include bone preparation at the implant-bone interface.
US10893944B2 Methods of modifying the porous surface of implants
Methods are provided for modifying a porous surface of an implantable medical device by subjecting the porous surface to a modified micro-arc oxidation process to improve the ability of the medical device to resist microbial growth, to improve the ability of the medical device to adsorb a bioactive agent or a therapeutic agent, and to improve tissue in-growth and tissue on-growth of the implantable medical device.
US10893936B2 Optical device and method for modifying the refractive index of an optical material
An optical device comprising an optical hydrogel with select regions that have been irradiated with laser light having a pulse energy from 0.01 nJ to 50 nJ and a wavelength from 600 nm to 900 nm. The irradiated regions are characterized by a positive change in refractive index of from 0.01 to 0.06, and exhibit little or no scattering loss. The optical hydrogel is prepared with a hydrophilic monomer.
US10893930B2 Stent graft
Stent graft consisting of a stent (1) comprising a plurality of ring segments (3, 4) having a meandering configuration arranged side by side and connected with each other by connecting webs (6), and at least one membrane (2) covering the entire outer side of the stent (1), being wrapped inwards around the ends of the stent and fixed between loops of ring segments (4) and connecting webs (6) that join the adjacent ring segments (3, 4) with each other, wherein the membrane (2) is fixed between at least two loops of the second ring segment (4), viewed from the ends of the stent (1), and the connecting webs (6) to the neighboring terminal ring segment (3).
US10893925B2 Instrument for preventing male urinary incontinence and cover
A urinary incontinence prevention instrument for males includes: an annular part made by forming a portion of a belt-like component; a convex part for pressing the urethra attached to the inner circumference surface side of the annular part; an adjustment mechanism for adjusting the diameter of the annular part; and a pinching-prevention component having a hole for passing the belt-like component, a lower part of the pinching-prevention component is positioned between the penis and the adjustment mechanism, preventing the skin of the penis from being pinched in the adjustment mechanism, the adjustment mechanism is located inside the hole, and both ends of the belt-like component pass through the inside of the hole and penetrate an upper part of the pinching-prevention component, the lower part of the pinching-prevention component and the convex part for pressing the urethra are at positions facing each other with the penis sandwiched in between.
US10893922B2 Electric apparatus unit
An electric apparatus unit comprises electric apparatus and charging stand. Electric apparatus includes rechargeable battery, a driver that drives through electric power supplied from rechargeable battery and power receiver that supplies the electric power to rechargeable battery. Charging stand includes power transmission coil that supplies electric power to power receiver and support that supports electric apparatus.
US10893920B2 Modeling a digital design of a denture
A method for modeling a digital design of a denture for a patient, the denture includes a gingival part and a teeth part including a set of denture teeth, where the method includes obtaining a digital 3D representation of the patient's gum; obtaining virtual teeth models corresponding to the denture teeth; virtually arranging the virtual teeth models in relation to the digital 3D representation of the patient's gum; and generating a virtual outer gingival surface of the gingival part of the denture.
US10893919B2 Optimization of superstructures and/or mesostructures in dental prostheses
A method and device for developing a geometry of a superstructure and/or mesostructure for dental prostheses. According to one aspect of the invention a method of developing a geometry of a mesostructure for a dental prosthesis includes the following steps: receiving first 3D data defining a 3D installation space for a mesostructure, receiving second 3D data defining possible positions for attaching the mesostructure, receiving third 3D data defining possible positions or regions for attaching the dental prosthesis to the mesostructure, and developing an optimized geometry of the mesostructure by means of an optimization technique, wherein starting from the 3D installation space the possible positions for attaching the mesostructure and the possible positions or regions for attaching the dental prosthesis to the mesostructure, the geometry of the mesostructure is optimized by means of applying the physical laws.
US10893915B2 Surgical system and method
A spinal construct includes a first member having a first thread form and an implant cavity configured for disposal of the spinal implant. A second member is engageable with a spinal implant and includes a second thread form configured for engagement with the first thread form. A gauge is coupled to the second member. The gauge is configured to measure a force between the second member and the spinal implant when the second member is engaged with the first member. The second thread form is timed with the first thread form to position the gauge in a selected orientation relative to the spinal implant. Systems and methods are disclosed.
US10893911B2 Automated image cropping for enhanced automatic device-to-image registration
Systems, methods, and computer-readable media are provided. Some embodiments include obtaining image data of a subject and a medical device, the medical device including fiducial markers, wherein the image data includes three-dimensional image data. Information is generated representing a three-dimensional shape based on a planned insertion point for performing a medical procedure. A cropping process is applied to the image data to generate cropped image data based on the three-dimensional shape. In some embodiments, the cropped image data includes image data of at least two of the fiducial markers. Fiducial marker objects are detected within the cropped image data, and the fiducial marker objects are registered by matching a model of the fiducial markers with the fiducial marker objects.
US10893907B2 Medical skin wrinkle improvement device using peak of laser pulse wave
The present invention relates to a medical skin wrinkle improvement device using a peak of a laser pulse wave, and more specifically, to a medical skin wrinkle improvement device using a peak of a laser pulse wave, thereby lowering the degree of carbonization of a skin tissue having the laser irradiated thereon, thus enhancing a skin generation effect and shortening recovery time. The present invention comprises: a main body (100) which has formed on the upper part thereof a holding groove (110) having a tablet computer (200) attached/detached thereto, and which has mounted therein a controller (120) for controlling a hand piece (300) and the tablet computer (200); the hand piece (300) which comprises a laser oscillation unit (320), an optical unit (330) and a laser scanner, the laser oscillation unit (320) generating a laser to be irradiated for skin treatment, the optical unit (330) irradiating, as a parallel light, the laser generated by the laser oscillation unit (320), and the laser scanner adjusting the irradiation location of the laser transferred from the optical unit (330); and the tablet computer (200) which is provided with data input and screen display functions by means of a touch screen method, and which remotely controls the main body (100) through the transmission/reception of a bi-directional wireless signal.
US10893906B2 Tailored laser pulses for surgical applications
A laser system may include a controller configured to direct a plurality of temporally spaced-apart electrical pulses to a device that optically pumps a lasing medium, and a lasing medium configured to output a quasi-continuous laser pulse in response to the optical pumping. The plurality of temporally spaced-apart electrical pulses may include (a) a first electrical pulse configured to excite the lasing medium to an energy level below a lasing threshold of the lasing medium, and (b) multiple second electrical pulses following the first electrical pulse. The quasi-continuous laser pulse is output in response to the multiple second electrical pulses.
US10893904B2 Temperature controlled short duration ablation
A method, including selecting a first maximum radiofrequency (RF) power to be delivered by an electrode within a range of 70 W-100 W, and selecting a second maximum RF power to be delivered by the electrode within a range of 20 W-60 W. The method also includes selecting an allowable force on the electrode within a range of 5g-50g, selecting a maximum allowable temperature, of tissue to be ablated, within a range of 55° C.-65° C., and selecting an irrigation rate for providing irrigation fluid to the electrode within a range of 8-45 ml/min. The method further includes performing an ablation of tissue using the selected values by initially using the first power, switching to the second power after a predefined time between 3 s and 6 s, and terminating the ablation after a total time for the ablation between 10 s and 20 s.
US10893902B2 Integrated resistive filters in catheter distal end
A distal-end assembly of a medical device, the distal-end assembly includes a flexible substrate and electrical conductors. The flexible substrate is configured to be coupled to a distal end of an insertion tube. The electrical conductors are disposed on the flexible substrate and are shaped to form: (i) one or more electrodes, configured to exchange electrical signals with a proximal end of the medical device, and (ii) one or more printed filters shaped to form at least a resistor, which are disposed adjacently to at least one of the electrodes and are configured to filter signals in a predefined frequency range from the electrical signals exchanged between the at least one of the electrodes and the proximal end.
US10893883B2 Ultrasonic assembly for use with ultrasonic surgical instruments
A surgical instrument includes an ultrasonic transducer assembly comprising a coupling portion laterally movable at an ultrasonic frequency. In addition, the surgical instrument includes an ultrasonic transmission waveguide extending from the coupling portion and an ultrasonic treatment element defining a cutting surface, wherein the ultrasonic treatment element extends from the ultrasonic transmission waveguide, and wherein the lateral movement of the coupling portion is in a direction perpendicular to a plane defined by the cutting surface of the ultrasonic treatment element.
US10893882B2 Atherectomy motor control system with tactile feedback
An atherectomy system includes a handle and a drive motor that is adapted to rotate a drive cable extending through the handle and operably coupled to an atherectomy burr. A control system is adapted to regulate operation of the drive motor, including providing the drive motor with a high frequency pulse width modulation (PWM) drive signal in order to operate the drive motor. The control system monitors a motor performance parameter such as motor speed or motor torque, and when the motor performance parameter approaches a limit of a performance range, the control system adds a low frequency PWM signal to the high frequency PWM drive signal, thereby causing the drive motor to produce a tactile signal that signals to the user that the motor performance parameter is approaching the limit of the performance range.
US10893880B1 Body-specific derma roller
A derma roller apparatus has a head, which has a cylindrical member and a plurality of needles situated around the cylindrical member. The width of the cylindrical member may be in a range of four to twelve inches. Furthermore, each of the plurality of needles may have a length of at least five tenths millimeters. In addition, the derma roller apparatus has a swivel, a connector, and a handle. The connector connects to a first endpoint of the head and a second endpoint of the head. Furthermore, the handle is operably attached to the connector via the swivel. The handle is configured to move along a yaw axis with respect to a collinear plane that is collinear with the head and the handle. Finally, the first endpoint and the second endpoint of the head are transverse to the collinear plane. As an alternative, the handle may be telescopic.
US10893878B2 Systems and methods for implanting surgical implants
The present invention relates to an implant system that comprises an implant, a handle configured to removably receive the implant, and, in some embodiments, a spacer tool configured to be mounted on the implant. In further embodiments, a k-wire is employed to guide the implant to a desired location. The handle has a hole for receiving a first portion of the implant. Using the handle to implant the implant, along with an associated spacer, provides a quick and convenient method for implanting the implant as described herein and in the associated drawings.
US10893873B2 Unicortal path detection for a surgical depth measurement system
Unicortical path detection for a measurement system for monitoring a depth of penetration of a working portion of an instrument in a bone of a patient. The unicortical detection may compare an average cortex thickness in a bicortical path to an actual measured depth of penetration. If the actual depth of penetration exceeds the average thickness, a unicortical path may be detected. Upon detection of a unicortical path, an alert may be provided and/or the instrument may be arrested upon subsequent breaching of the cortex.
US10893872B2 Hemostatic device
A hemostatic device includes a band configured to be wrapped around a wrist, and to be secured in a state where the band is wrapped around the wrist, and an inflatable portion that interlocks with the band and that is inflated by injecting gas. The inflatable portion has a first region formed of a thermoplastic material and a second region formed of a thermosetting elastomer whose gas permeability is higher than that of the thermoplastic material. The band has an interlock region which is formed of the thermoplastic material, and with which the inflatable portion interlocks. The first region of the inflatable portion is welded to the interlock region of the band. The compressing force of the inflatable portion can be reduced over time to inhibit vascular occlusion.
US10893870B2 Vaso-occlusive device
A vaso-occlusive device includes an inner braided member having an unconstrained deployed configuration and a constrained delivery configuration. The inner braided member includes a first plurality of filaments made of a first material composition, where a pair of filaments of the first plurality defines a first braid angle when the inner braided member is in the deployed configuration. The device also includes an outer braided member disposed at least partially around the inner braided member, and having an unconstrained deployed configuration and a constrained delivery configuration. The outer braided member includes a second plurality of filaments made of a second material composition different from the first material, where the first material has a greater radiopacity than the second material. A pair of filaments of the second plurality defines a second braid angle, substantially equal to the first braid angle, when the outer braided member is in the deployed configuration.
US10893868B2 Aneurysm treatment coils
Systems and devices for endovascular treatment of intracranial aneurysms are described. Various configurations of coiled implants may be used as stenting devices or aneurysm coils. The implants include one or more filaments wound about a longitudinal axis to form a generally tubular shape. Lateral flexibility of the implants may be manipulated by, for example, adjusting a pitch between adjacent filaments, using different materials for the filaments, employing different filament cross-sectional shapes, grouping filaments into pluralities of varying flexibilities, and nesting inner coils within outer coils.
US10893867B2 Drive train control arrangements for modular surgical instruments
A surgical instrument comprises an end effector, a shaft, and a housing extending proximally from the shaft. The surgical instrument includes an articulation assembly configured to articulate the end effector relative to the shaft, a firing assembly configured to fire a plurality of staples, for example, and a locking member movable between a locked configuration and an unlocked configuration. The housing is removably couplable to the shaft when the locking member is in the unlocked configuration and the housing includes a motor configured to drive at least one of the firing assembly and the articulation assembly. The housing also includes a controller in communication with the motor, wherein the controller is configured to activate the motor to reset at least one of the firing assembly and the articulation assembly to a home state when the locking member is moved between the locked configuration and the unlocked configuration.
US10893865B2 Magnetic wound closure systems
Devices, systems, and methods can be used for the closure of surgical wounds. For example, surgical wounds can be closed using magnetic closure devices rather than the conventional methods of using sutures, clips, or staples. Additionally, in some implementations the magnetic closure devices provided herein are delivered laparoscopically or endoscopically via a vacuum catheter.
US10893863B2 Staple cartridge comprising offset longitudinal staple rows
A staple cartridge assembly is disclosed which comprises offset staple rows.
US10893860B2 Method of performing a tendon replacement
A method of performing a tendon replacement, of a tendon connecting a first bone and a second bone, in an animal body utilizing a suture assembly that includes the following construction. A button has two apertures and a suture, engaged to the button, defines a lumen and forms a double loop, formed by a double trap that is opposed to the button. The suture assembly further defines a first single trap, and a third trap. In the method, a drill hole is drilled sequentially through the two bones. Also, a length of tendon tissue is draped over the loop and the button is passed through the drill hole through the first bone and the second bone and the button is oriented to sit on a surface of the second bone and the suture ends extend outwardly through the drill hole.
US10893859B2 Implant adapted to treat urinary incontinence
An implant adapted to treat urinary incontinence includes a support material, a suture, and an anchor. The support material is provided to support the urethra when implanted in a patient. The suture is inserted through the support material and includes a first trailing end portion and a second trailing end portion. The anchor has a body, a fin extending from the body with an eyelet formed in the fin and the suture passed through the eyelet of the fin, and a gripping tab removably attached to the fin. The gripping tab is removable from the fin prior to insertion of the anchor into tissue.
US10893858B2 Tap-in bone anchor with expanding ring
An anchoring device for holding suture in bone includes an implant body with a proximal end and a distal end. A distal opening of the implant body is configured to receive a first proximal portion of an anchor. An expandable ring is initially press-fit about the first proximal portion of the anchor. The anchoring device is then located in a pre-drilled bore in a bone portion and the anchor portion is drawn proximally into the implant body, causing the ring to expand and contact the inner walls of the bone bore thus providing additional locking force of the anchoring device in the bone.
US10893856B2 Wound closure product
A wound closure system and a method of closing a wound are disclosed. The disclosure is directed to a wound closure system comprising a skin anchor mechanically attached to external skin tissue on a first side of a generally linear wound, an anchorable tensioning apparatus mechanically attached to external skin tissue on an opposite side of the wound, and a line extending between the skin anchor and the tensioning apparatus to movably connect the anchor to the tensioning apparatus. The line is fixedly engaged with an anchor on one side of the wound while the tensioning apparatus provides tension on the line to draw the skin anchor and the tensioning apparatus toward each other and toward the wound.
US10893855B2 Retractor system and retractor with detachable handle
A retractor system includes a retractor blade and a handle assembly. The retractor blade includes a base portion, a blade extending from the base portion, and a handle mount affixed to the base portion. The handle assembly includes an attachment portion and a retaining rod. The attachment portion includes a slot configured to receive the handle mount, a first cavity adjoining the slot, a retaining member moveable along the first cavity, and a second cavity adjoining the first cavity. Advancement of the retaining rod through the second cavity and into the first cavity advances the retaining member into the slot and into engagement with the handle mount.
US10893849B2 Ultrasound image diagnosis apparatus, medical image processing apparatus, and computer program product
According to one embodiment, an ultrasound image diagnosis apparatus includes a display and a control circuit. The display is configured to display an ultrasound image generated based on an echo signal of ultrasound waves transmitted to a site to be diagnosed. The control circuit is configured to measure a measurement target on the ultrasound image of the site to be diagnosed displayed on the display. The control circuit performs a definition function to define the distance between a caliper used to measure the measurement target and a guide used to arrange the caliper at the position of the measurement target, a display control function to control the display of the caliper and the guide arranged to be separated by the distance defined such that the caliper and the guide are integrally movable on the ultrasound image, and a measurement function to measure the measurement target using the caliper.
US10893843B2 System and method for identifying and marking a target in a fluoroscopic three-dimensional reconstruction
A method and system for facilitating identification and marking of a target in a displayed Fluoroscopic Three-Dimensional Reconstruction (F3DR) of a body region of a patient. The system includes a display and a storage device storing instructions for receiving an initial selection of the target in the F3DR, fining the F3DR based on the initial selection of the target, displaying the fined F3DR on the display, and receiving a final selection of the target in the fined F3DR via a user selection. The system further includes at least one hardware processor configured to execute said instructions. The method and instructions may also include receiving a selection of a medical device in two two-dimensional fluoroscopic images, where the medical device is located in an area of the target, and initially fining the F3DR based on the selection of the medical device.
US10893842B2 System and method for pose estimation of an imaging device and for determining the location of a medical device with respect to a target
A system and method for estimating a pose of an imaging device for one or more images is provided.
US10893841B2 Radiography apparatus
The radiography apparatus of the present invention includes a CPU 71 having a function of a lighting time limitation means to control the lighting time of light sources in such a way as to maintain a temperature at or below a predetermined temperature. In order to discriminate the type of light source connected to the device body, the setting of No. 5 pin on the CPU 71 to a high logic state or a low logic state is detected. This enables the detection of whether the light source connected to a control board 70 is a halogen lamp H or a light emitting diode (LED) L. Thus, the type of the light source is discriminated. The CPU 71 changes the controlled limiting lighting time based on the result of discrimination. This prevents the risk of incorrectly carrying out settings and enables the automatic setting for switching light sources.
US10893839B2 Computed tomography system and method configured to image at different energy levels and focal spot positions
A computed tomography (CT) imaging system and method, wherein the system includes an x-ray source that is operable to emit a beam of x-rays from a focal spot and move a spot position of the focal spot. The system also includes a detector assembly that is configured to detect the x-rays attenuated by the object. At least one processing unit is configured to execute programmed instructions stored in memory. The at least one processing unit is configured to direct the x-ray source to emit different beams of the x-rays at different energy levels and to receive data from the detector assembly that are representative of detection of the x-rays emitted at the different energy levels. The at least one processing unit is also configured to direct the x-ray source to move the focal spot such that the focal spot is at different spot positions while the different beams are emitted.
US10893835B2 Physiological monitoring devices with adjustable signal analysis and interrogation power and monitoring methods using same
A monitoring device configured to be attached to a body of a subject includes a sensor configured to detect and/or measure physiological information from the subject, and a processor coupled to the sensor that is configured to receive and analyze signals produced by the sensor. The processor is configured to change signal analysis frequency and/or sensor interrogation power in response to detecting a change in subject activity, a change in subject stress level, a change in environmental conditions, a change in time, and/or a change in location of the subject.
US10893832B2 Predictive instrument to identify patients for use of pharmacological cardiac metabolic support
A purpose-made predictive instrument for the administration of cardiac metabolic support for acute coronary syndromes (ACS, which include unstable angina and acute myocardial infarction) that particularly identifies those most likely to benefit from treatment. In some examples, such a predictive instrument is used for real-time decision support for the administration of treatments such as glucoseinsulin-potassium (GIK).
US10893831B2 Electronic management of sleep related data
A system and method electronically manages sleep related data obtained by a diagnostic device. The system and method may include collecting sleep data from a patient using a diagnostic device. The sleep data may be stored in a sleep data file and delineated as multiple sleep sessions. A user may access the stored sleep data by selecting a particular sleep session. The sleep data for the selected sleep session may then be extracted from the sleep data file and presented to the user as a combination of image tiles, JavaScript elements, and an event indicator.
US10893829B2 Optical detection and measurement of hematocrit and free hemoglobin concentration
A colorimetric optical sensor device includes a broadband light source configured to emit a light that is exposed to a fluid in a vessel. At least a portion of the light is reflected off of the fluid and received by an optical spectrometer. The optical spectrometer analyzes at least a portion of the received light to determine a main wavelength of the light. A controller correlates the main wavelength to a corresponding hematocrit or free hemoglobin concentration and generates an output indicative of the hematocrit or the free hemoglobin concentration of the fluid. The hematocrit or free hemoglobin concentration information may be used by a separation assembly in which the colorimetric optical sensor device may be incorporated to modify a separation procedure in which the monitored fluid is to be separated or is a component or constituent of a previously separated biological fluid.
US10893823B2 Method and apparatus for the assessment of electrophysiological signals
Apparatus for the assessment of electrophysiological signals obtained from a patient, the apparatus comprising: a housing; a support arch pivotally mounted to the housing, the support arch comprising a plurality of facial contact point supports for supporting contact points on the face of the patient relative to the support arch without supporting the chin of the patient; at least one display screen for presenting a stimulus to a single eye of the patient, the at least one display screen being movable relative to the support arch; and control electronics disposed within the housing for driving the at least one display screen and for amplifying electrophysiological signals obtained from the patient.
US10893815B2 Heart rate measurement and a photoplethysmograph (PPG) heart rate monitor
A method for heart rate measurement in a photoplethysmograph (PPG) heart rate monitor device is provided that includes performing motion compensation on a PPG signal wherein a motion compensated PPG signal PPGaccX is generated with reference to an X-axis acceleration signal, a motion compensated PPG signal PPGaccY is generated with reference to a Y-axis acceleration signal, and a motion compensated PPG signal PPGaccZ is generated with reference to a Z-axis acceleration signal, combining PPGaccX, PPGaccY, and PPGaccZ to generate a final motion compensated PPG signal, wherein a first weight is applied PPGaccX, a second weight is applied to PPGaccY, and a third weight is applied to PPGaccZ, performing a single Fourier Transform (FT) on the final motion compensated PPG signal to generate a frequency domain PPG signal; and estimating a heart rate based on the frequency domain PPG signal.
US10893810B2 Image processing apparatus that identifiably displays bleeding point region
A video processor includes: a region extracting circuit that receives an input of a first image signal obtained by forming an image of a subject irradiated with first narrow band light including a wavelength that is minimally absorbed by blood within a green wavelength band, the image of the subject including a bleeding point, and extract a blood pool region having a blood concentration that is lower than a blood concentration of the bleeding point in a region representing the blood in the first image signal; and an image generating circuit that raises a luminance value of the blood pool region in either the first image signal or a second image signal obtained by forming an image of the subject irradiated with second narrow band light whose wavelength is shorter and which is more absorbed by the blood than the first narrow band light.
US10893803B2 Wide-field retinal imaging system
A retinal imager for imaging a retina of an eye includes an illumination source operable to generate illumination light and a beam splitter operable to receive the illumination light and direct the illumination light along an optical axis. The retinal imager also includes a field lens disposed along the optical axis and an objective lens disposed along the optical axis and operable to contact a cornea of the eye. An aerial image is formed adjacent to the field lens. The retinal imager further includes an image sensor and one or more lenses disposed along the optical axis between the beam splitter and the image sensor. The one or more lenses are operable to form a sensor image at the image sensor.
US10893800B2 Binocular measurement device, binocular measurement method, and binocular measurement program
An object is to simply and easily evaluate differences in behavior of the eyes of subjects. A binocular measurement system 1 includes a photodetector 7 that detects reflected light from the right eye ER and the left eye EL of a subject, and outputs image signal of the reflected light, a feature amount calculating unit 11 that calculates a feature amount corresponding to the right eye ER and a feature amount corresponding to the left eye EL based on the image signal, and a comparison value calculating unit 13 that calculates, based on the two feature amounts, a comparison value obtained by comparing the two feature amounts.
US10893798B2 Methods and systems for updating refractive prescriptions and delivering eyeglasses and contact lenses
Methods and systems for producing a refractive prescription for a consumer away from an optical office are disclosed. At a first time point, a first prescription for a first pair of corrective lenses is generated according to measured refractive errors, and a historical visual acuity profile is measured using the first prescription and a varying spherical power. At a second time point, a second visual acuity is measured using the first prescription. A new spherical power is computed using the historical visual acuity profile and the second visual acuity. A second prescription for a second pair of corrective lenses is generated based on the first prescription and the new spherical power. In some embodiments, the second visual acuity may be self-administered by the consumer away from an optical office.
US10893791B2 Dishwasher and sump assembly
A dishwasher includes a tub at least partially defining a treating chamber with an access opening, a sump fluidly coupled to the treating chamber, at least one sprayer emitting liquid into the treating chamber, a pump, a conduit fluidly coupling the sump to the pump and the pump to the at least one sprayer, thereby defining a recirculation circuit through which the liquid sprayed into the treating chamber collects in the sump and is pumped back to the at least one sprayer, a filter assembly provided in the sump and having a filter through which at least a portion of the liquid passes, and an insert sleeve at least partially located within the filter assembly.
US10893786B2 Portable extractor
A portable extractor includes a supply tank, a recovery tank, a pump in fluid communication with the supply tank, a suction source in fluid communication with the recovery tank, a base configured to support the suction source and the pump, and a main housing mounted on the base and housing the suction source and the pump. The main housing is configured to removably support the recovery tank and the supply tank. The recovery tank is arranged at a front side of the portable extractor and the supply tank is arranged at a lateral side of the portable extractor between the front side and the rear side.
US10893785B2 Cleaning appliance
A cleaning appliance includes a dirt separator for separating dirt from an airflow, and a main body, the dirt separator including a bin for collecting dirt separated from the airflow, and the main body including a runner portion extending alongside a side wall of the bin, wherein the bin is slidable along the runner portion between an operational position and an extended position, and a release catch releasably engages with a formation on the runner portion to prevent the bin from being separated from the cleaning appliance, and wherein the release catch is positioned on the side wall of the bin such that it is hidden by the runner portion of the main body unless the bin is in the extended position.
US10893784B2 Suction hose connecting piece
A suction hose connecting piece for a suction hose for producing a flow connection from a machine tool to a vacuum cleaner, the connecting piece including a tubular body with a circumferential wall that delimits a flow channel, and a plug section which is arranged on the tubular body for the purpose of producing a plug connection with a mating connecting piece, it being possible to plug the connecting piece and mating connecting piece one onto the other along a longitudinal axis of the plug section, a longitudinal latch contour being arranged on the plug section, counteracting release of the mating connecting piece from the connecting piece relative to the longitudinal axis, and engaging with a longitudinal mating latch contour of the mating connecting piece when the mating connecting piece is plugged onto the connecting piece, along the longitudinal axis of the plug section.
US10893783B2 Surface cleaning apparatus
A reconfigurable upright vacuum cleaner has a portable surface cleaning unit removably mounted to an upper portion. The portable surface cleaning unit has a suction motor and an air treatment member. The air treatment member is removably mounted to the portable surface cleaning unit and secured in position by an air treatment member lock. The portable surface cleaning unit is secured in position by a portable surface cleaning unit lock. When the portable surface cleaning unit is mounted to the upper portion and the upper portion is in the storage position, the portable surface cleaning unit actuator is provided on an upper end of the portable surface cleaning unit and the air treatment member release actuator is provided on an upper end of the air treatment member.
US10893781B2 Authentication reader and a dispenser comprising the authentication reader
An authentication reader and a dispenser comprising the authentication reader for authenticating a product having a taggant ink disposed on the product's surface.
US10893778B1 Serving spoon with depression forming feature
A serving spoon has a spoon portion with a depression portion that forms a depression in a serving of malleable food product, thereby allowing some other food product to be retained within the depression. The serving spoon includes a spoon portion and a handle portion. The spoon portion has a concave body and a depression portion configured within the concave body, wherein the depression portion extends up from the bottom of the concave body. The depression portion forms a depression, in a malleable food product. The spoon portion may be detachable from the handle portion.
US10893777B2 Cooking grill ignition system
An Electro-Mechanical Pulse Generator (“EMPG”) may be used to ignite an ignition pad comprising of fine carbon steel fibers. When electrical energy is applied to the carbon steel fibers, the carbon steel ignites thus starting the combustion of the fuel in a fuel basket located within the grill's combustion chamber. An electrical control panel connects an energy source such as a battery with an ignition wire positioned within the combustion chamber of the grill. A fan positioned below or near the fuel basket controls the amount of air flow into the combustion chamber to aid in initially lighting the fuel as well as controlling the temperature of the grill and the amount of combustion used to heat the food that is cooking.
US10893776B1 Cooking plate with temperature sensing element
A cooking plate includes a metal plate for cooking; a heating element, which is in contact with the metal plate and is configured to heat the metal plate; and a temperature sensing element which is integrated with the metal plate and which is configured to sense a temperature of the metal plate and outputs a sensing signal for control heating of the heating element.
US10893774B2 Espresso milk frother probe
A milk frothing apparatus which includes a steam probe which consists of an inner steam tube surrounded by an outer tube spaced annularly from the inner tube with a nozzle mounted on the end of the outer tube adjacent the outlet end of the inner tube. The air gap between the inner and outer tubes insulates the outer tube from the heat generated in the inner tube during the steam cycle. By using stainless steel the milk does not stick to the cool outer tube surface and no cleaning of the outer surface of the probe is necessary. The steam itself keeps the inner surfaces of the probe clean.
US10893773B2 Unit, device and system for preparing beverage consumptions
The beverage preparation unit comprises a mixing chamber having a beverage outlet, a liquid flow path for supplying a liquid to the mixing chamber, and an air flow path for supplying air to the liquid flow path. The mixing chamber is arranged for receiving a beverage related ingredient, such as concentrate, preferably from an exchangeable supply pack. The liquid flow path is arranged for generating a hollow jet of liquid having an outer liquid portion extending in a flow direction of the jet and an inner air portion extending in a flow direction of the jet wherein the outer liquid portion surrounds the inner air portion.
US10893770B2 Pumping system and method for a beverage production apparatus
The present invention presents a pumping system (1) with a preheated reservoir (2), a main pump (4) for pumping a preheated liquid (3) from the reservoir (2), and pressurizing means (5) for pressurizing the reservoir (2). Preferably, the pressurizing means set an absolute pressure of 0.5 to 1 bar in the reservoir (2). The liquid (3) in the reservoir (2) can be heated up to 90° C. or more. The present invention achieves a nearly complete suppression of the phenomenon of cavitation at the main pump entrance, and thus achieves an increased pumping performance at elevated liquid temperatures.
US10893766B2 Plant fiber straw structure
An environmentally-friendly fiber straw structure includes a straw body made of an environmentally-friendly fiber material. The straw body has an inlet and an outlet at two ends thereof and a circular section having a circular cross-section between the inlet and the outlet. From the circular section to the outlet forms a first tapered section at a first inclination so that the outlet has an approximately elliptical shape. When in use, the mouth of a user sucks the outlet of the straw body for drinking a beverage, the first tapered section corresponds in shape to the mouth, thereby avoiding rotation of the straw body, reducing a gap between the mouth and the straw body.
US10893765B2 System and method of an attachable spice dispensing device for an automatic meal preparation apparatus
A spice dispensing device is provided for an automatic meal preparation apparatus. The device uses a replaceable cartridge containing a volume of spice for dispensing in predetermined volumetric doses. A dispensing mechanism is built in to the cartridge for isolating the predetermined volumetric dose and moving it toward an opening in the bottom of the cartridge. The cartridge is sized and shaped to be placed into the automatic meal preparation apparatus in a rack for containing a plurality of such cartridges. The cartridge is alignable with a position in the rack in which the spice dose can be dispensed directly into a cooking vessel of the apparatus.
US10893762B2 Pillow apparatus
Embodiments of the present invention are directed to a pillow apparatus that is structured to support a user's limbs or legs. The pillow apparatus typically comprises a pillow body. The pillow body typically comprises a first concave depression positioned on a first surface of the pillow body. The first concave depression is structured to support at least a portion of a thigh of a user or a portion of crus leg part of the user. In some embodiments, the pillow body also comprises a second concave depression positioned on a second surface of the pillow body, opposite the first surface. Moreover, in some embodiments, the pillow apparatus comprises a coupling member structured for releasably connecting the pillow apparatus with an adjacent pillow apparatus.
US10893755B2 Device and methods for reducing back injury
A backsaving device having a main body sized and shaped to corresponding to the height of an under-sink cabinet, such that when the backsaving device is disposed adjacent the under-sink cabinet, a top surface of said main body is generally coplanar with a bottom interior of said under-sink cabinet. This allows a worker working under the sink to lay back on the device comfortably without the edge of the cabinet digging into the back or shoulders. A rotatably flip may be used to bridge the gap between the device and sink to prevent pinching.
US10893752B2 Chair with activated back flex
A chair back that includes a back support, an upright frame, and at least one flex wing. The back support is substantially flexible and has a first side portion and a second side portion. The upright frame is substantially rigid and has a first frame side and a second frame side. The flex wing is located between the first frame side and the first side portion, where the flex wing includes a front portion coupled to the first side portion, a back portion coupled to the first frame side, and a web portion interconnecting the front portion and the back portion. The flex wing flexes during engagement by a user.
US10893750B2 Method for producing seat core material, and seat core material
A method for producing a seat core material that has a foamed molded substrate and a frame member embedded in a periphery thereof, which includes, as step (a), heating thermoplastic resin expanded beads in a mold cavity, in which the frame member has been disposed, to fusion-bond the expanded beads to each other and to obtain the foamed molded substrate with the frame member being embedded in the periphery thereof; and, as step (b), simultaneously with step (a) or after step (a), forming a void cavity S, S′ in the foamed molded substrate at a position along and adjacent to the frame member. The void cavity S, S′ has a size and shape that allows a relative displacement between the frame member and the foamed molded substrate when the foamed molded substrate shrinks after step (b).
US10893744B2 All-in-one antimicrobial hand/nail brush
This personal All in One Antimicrobial Hand Brush offers a novel function from the existing art. The most convenient and effective method for removing pathogens from the hands whether at home or outside the home. It includes a bristle side used for sweeping under the nailbed and a sponge side to clean the hands. Both sides are connected to a base containing a chamber inside. The chamber contains a barrier filled with a personal care solution(s) released by squeezing the hourglass indentation after pulling the tab to remove the barrier. The barrier prevents the solution from leaking prior to use. The device will also be available to provide the same optimal method to clean in-between pet paws for dogs and cats. Pets commonly carry pathogens found in soil and grass. Wiping paw pads alone will not remove these pathogens similar to hand washing without sweeping under the human nail bed.
US10893743B1 Portable computing device holster
A portable computing tablet holster comprising a handle assembly attached to a portable computing tablet retention assembly. The portable computing tablet retention assembly is adapted to retain a portable computing tablet therein using a pair of elongated retention channels extending along opposite elongated edges of a tablet rear support panel. The tablet is retained by a lateral retention channel extending along a lateral edge and at least one flexible retention element located proximate an opposite lateral edge thereof. The handle assembly can be rigidly fixed to the rear panel or moveably assembled to the rear panel. Movement between the handle and the rear panel can include a sliding movement, a rotating movement, and/or a pivoting movement. A user input device can be integrated into the handle for controlling at least one of a light and/or a camera integrated into the holster, the tablet, and the like.
US10893742B1 Device for holding a phone
A clip may be placed over the thigh of a driver. At the top of the clip, a bracket assembly is provided. The bracket assembly includes, in the preferred embodiment, a telescoping rod attached to the clip via a ball and socket joint allowing pivoting of the telescoping rod in all directions. On top of the telescoping rod, a cross-shaped phone holder is provided with arms configured to hold a smart phone or cell phone.
US10893738B2 Applicator for applying cosmetic product, notably for applying mascara to the eyelashes
The present invention relates to an applicator member (1) for an applicator for applying cosmetic product, notably for applying mascara to the eyelashes, said applicator member comprising a metal core (2) having an end (2a) for connecting to a gripping member (5), characterized in that said connecting end is shaped so as to be able to form a joint head that is able to engage in a corresponding housing in the gripping member, and in that said connecting end is produced by moulding in one piece with the metal core.
US10893737B1 Nail lamp with rechargeable battery pack
A nail lamp for curing UV-curable nail gel uses light emitting diodes (LEDs) that emit ultraviolet light and are relatively lower power. The nail lamp is powered from an exterior power source, such as a wall socket, or by a rechargeable battery pack. A battery compartment of the nail lamp holds the battery pack, which is removable without disassembling the nail lamp. The nail lamp is easily transportable to different locations and can be used even when a wall socket is unavailable. A curing time of the nail lamp is user-selectable. The nail lamp can also include detection sensors to detect a person's hand or foot in a treatment chamber and automatically turn on or off the LEDs.
US10893735B2 Hands-free grooming apparatus and methods of use thereof
A hands-free grooming device configured to align with a center point on a user's chin and secure to the user's face via tension created between the user's face when a plurality of tabs are secured to form head and neck straps. Once secured, the grooming device enables the user to perform grooming operations without holding the grooming device in place, resulting in a consistently shaped beard with defined edges.
US10893734B1 Cut resistant and highly translucent tote
A cut resistant and highly translucent tote utilizes a multilayer knitted metal fabric having a knitted metal outside layer and a knitted metal inside layer. These two knitted layers may be independent in a portion of the tote, such as in a clear-view portion of the tote, configured to allow clear visibility of items retained in the tote. The independent layers of knitted fabric are highly cut resistant, as they can flex in multiple direction and also move and slide with respect to each other. The tote may have a gusseted base with a base-side sleeve extending at the intersection of the base and sides to allow the tote to be free standing. An opening in the top of the tote may have a closure feature, such as hook-and-loop fastener material.
US10893733B2 Accessory organizer for use with a luggage bag
Embodiments of the invention provide a module collapsible accessory organizer for use with a luggage bag. The accessory organizer includes foldable compartments. The compartments can each be collapsed down when necessary to free up interior volume of the luggage bag in which the accessory organizer is placed. The compartments can stack and fold onto each other, and be inserted into or removed from a luggage bag. The compartments can be attached to each other. The compartments are modular such that the accessory organizer can be configured to include any desired number of compartments. The compartments of the accessory organizer are quickly unfolded and deployed for easy access to personal contents stored therein. The accessory organizer is a standalone organizer when not stored in a luggage bag. The accessory organizer can be manufactured and shipped as a standalone organizer, and then used with a variety of already-existent luggage bags of various dimensions.
US10893732B2 Book enclosure for the storage, transport and display of decorative pins
A book enclosure for the storage, transport and display of decorative pins. The book has page (s) that open for the viewing, securing, protecting and safe transportation of decorative pins in which the page surface is comprised of a puncturable and resilient material for the piercing through and repositioning of the post (s) portion of a decorative pin(s) and defining a mounting surface for decorative pins. Between the page (s) there is a protective page to prevent decorative pins from contact and potential damage. A translucent front with a zipper allows for the display and viewing of decorative pins. A zipper closure allows for the secure closure to protect pins from falling out. The book has a removable strap for shoulder or cross-body portage or to hang for display. The back of the book has a pouch enclosure for the storage of pin backs.
US10893731B2 Card holder for credit cards and other cards
Card holder for bank cards, credit cards, debit cards, driving licences, electronic identity cards or similar cards, having a cuboidal housing with an interior for receiving at least one card, a card opening of the housing for inserting at least one card into the housing and pushing out at least one card from the housing, at least one dispensing element which is displaceable from a first position into a second position in order to be brought into engagement with the lower edge of a card in the interior and to push out the one card through the card opening from the housing, an actuating element which is coupled to the dispensing element in order to displace the dispensing element from the first position into the second position by actuating the actuating element, wherein a first spring apparatus is supported, on the one hand, on the dispensing element and, on the other hand, on the housing, wherein the first spring apparatus is able to be tensioned by displacing the dispensing element from the second position into the first position, a locking apparatus has a first locking element connected to the dispensing element and a second locking element retained in the housing so that the first and second locking elements are able to be locked together by displacing the dispensing element into the first position, and the actuating element is coupled to the locking apparatus in order to unlock the first and second locking elements by actuating the actuating element, so that the first spring apparatus displaces the dispensing element from the first position into the second position in order to push out the card thereby from the card opening.
US10893728B2 Jewelry having druzy or geode effect and methods of manufacture
A method of manufacturing an article of jewelry with a druzy or geode effect, the method including: forming an adhesion mixture by mixing metal particles with a silica, shell, and/or clay with polymer, optionally in a liquid to form an adhesion paste; applying the adhesion mixture to an article of jewelry; applying a plurality of gemstones to the applied adhesion mixture to form a gemstone layer; melting the adhesion mixture without significantly melting the article of jewelry; and cooling the adhesion mixture to bond the gemstone layer to the article of jewelry.
US10893724B2 Locking mechanisms in electronic devices
Locking mechanisms and electronic devices having locking mechanisms are described herein. In one example, a locking mechanism includes a latch configured to move between a locked position and an unlocked position, wherein a component of the electronic device is secured in the locked position and removable in the unlocked position. The locking mechanism further includes a memory wire in communication with the latch, wherein the memory wire is configured to contract in length to move the latch between the locked position and the unlocked position to release the component of the electronic device.
US10893723B2 Side release buckle device
A side release buckle device with a male and female member. The female member has a housing, a catch assembly, and at least one contact point. The male member can interlock with the female member and has an arm assembly, a catch assembly, and at least one contact point. At least one switch is formed by contact between contact point of the male member and contact point of the female member. An electrical circuit traverses the female and male member, so when the members are “locked” together, the switch is closed. The electrical circuit has a series of wires, a source of electrical energy, a currently limiting resistor, at least one switch, and an electrical element (at least one microcontroller or integrated circuit, a Bluetooth® RF transceiver, Wi-Fi® enablement). The device may have a computer chip activated upon closure of the switch, triggering activation of an external camera, or a GPS-tracking system. The device pairs with other communication devices.
US10893718B2 Individually conforming impact attenuating liner for a helmet
An impact-attenuating liner for a helmet includes a liner body made from an impact-absorbing material and a plurality of pads removably attached to an interior surface of the liner body, each of the pads being repositionable at different locations on the interior surface of the liner body. A retention system may be attached to the liner body and configured to secure the liner to the wearer's head during use. The liner may be configured to provide substantially uniform impact protection throughout the interior region of the helmet.
US10893712B2 Induction heating methods for bonding seams
Methods for bonding a seam using an inductively heated structure are provided. A three-dimensionally conformable structure is placed upon materials at a location of a desired seam for a clothing article. The structure contours to the surface and material as placed. The structure includes a conductive filling that may be inductively heated. The heated structure and conductive filling activate a heat-responsive adhesive at the location and bond the materials to one another to form the desired seam.
US10893710B2 Tactical hand warmer apparatus
The tactical hand warmers may have a first glove portion defining a first glove recess that is detachably connected to a second glove portion defining a second glove recess for allowing an individual to warm their hands within the first and second glove recesses either closely together when the first and second glove portions are attached or apart when the first and second glove portions are detached.
US10893705B2 Electronic cigarette
An electronic cigarette includes a battery assembly and an atomizer assembly within a housing with the battery assembly electrically connected to the atomizer assembly. The housing has one or more air inlets. A liquid storage component is in contact with a porous component of the atomizer assembly, with the porous component having a run-through hole. A heating wire is in an air flow path through the run-through hole.
US10893703B2 E-liquid bottole and electronic cigarette
The present disclosure provides an e-liquid bottle engageable with an electronic cigarette. The e-liquid bottle includes a main body (11), a cover (12), and a control switch (14); the cover (12) forms at least one liquid outlet (121); and the control switch (14) is arranged in the cover (12). The electronic cigarette includes a cartridge (21) and a liquid injection device (23); the cartridge (21) forms a liquid reservoir (A), and one end of the cartridge (21) comprises an end wall (223) and a second operation portion (222) extending axially outwards from the end wall (223); the end wall (223) forms one liquid injection opening (2231), the second operation portion (222) corresponds to the control switch (14); the liquid injection device (23) is arranged on the end of the cartridge (21) and forms a liquid injection channel and a first liquid inlet (2321) is formed in the liquid injection channel.
US10893701B2 Cellulose acetate particle aggregate, preparation method therefor and application thereof
A cellulose acetate particle aggregate, a preparation method therefor and an application thereof, which relate to the field of harm reduction additives in cigarettes. The cellulose acetate particle aggregate includes 49-99.5 wt % of cellulose acetate particles, 0-50 wt % of a second kind of particles, and 0.5-20 wt % of a binder. The preparation method involves selecting cellulose acetate particles and a second kind of particles in a certain ratio, or cellulose acetate particles alone, preparing particle aggregates by using an air fluidized granulation method while adding a binder thereto, and sieving the particle aggregates to obtain a cellulose acetate particle aggregate having a required particle size. The cellulose acetate particle aggregate has a porous structure, an irregular shape, and a rough and uneven surface, which help to improve the efficiency of filtering out particulate matters or one or more harmful ingredients in cigarette smoke.
US10893700B2 Smoking article filter with flavorant delivery system
A breakable capsule such as a seamless breakable capsule useful in a smoking article or a smokeless tobacco product includes an outer shell formed of a cross-linked agar matrix including at least one filler, and an inner core surrounded by the outer shell which comprises a liquid or gel based composition of a flavorant and/or non-flavorant. The cross-linked agar matrix is reinforced with carboxymethyl cellulose that is dispersed throughout the agar matrix so as to fill empty spaces in the agar matrix and inhibit the composition from passing through the empty spaces of the agar matrix.
US10893695B2 Probiotic bacterial strain of Lactobacillus plantarum and compositions and uses thereof in the treatment of inflammation
The present invention relates to a novel bacterial strain, L. plantarum GOS 42 (DSM 32131), isolated preparations and compositions thereof; and their use in medicine, especially in the treatment and/or prevention of inflammation.
US10893692B2 Method for the detoxification of gluten proteins from cereal grains and uses thereof in medical field
An improved method of detoxifying gluten proteins from cereal grains produces detoxified cereal grains with a reduction of antigenicity of toxic epitopes of gluten proteins by up to a range between 0 and 20 ppm. The detoxified cereal grains can be advantageously used for preparation of food products (e.g. bakery products, pasta or dairy products) having a manifest preventive and/or therapeutic effect for gut dysbiosis caused by bacterial or viral infective agents or by pathologies with a strong inflammatory or autoimmune component such as celiac disease, ulcerative colitis, Crohn's disease and irritable intestine syndrome.
US10893689B2 Solid beverage for conditioning blood stasis constitution and method for producing the same
The present application discloses a solid beverage for conditioning blood stasis constitution. The solid beverage comprises the following components in parts by weight: 21-55 parts of hawthorn, 9-33 parts of peach seed, 9-33 parts of gingko, 5-21 parts of Platycodon grandiflorus, 9-33 parts of dried tangerine peel, 0.5-4 parts of cinnamon, 9-33 parts of the root of kudzu vine, 2-21 parts of Dahurian angelica, 10-29 parts of dextrin, 7-25 parts of maltodextrin, 8-26 parts of soluble starch and 0.05-0.2 parts of aspartame. The solid beverage of the present application is simple and convenient to prepare, the raw materials used are all medicinal materials with dual-purpose of drug and food, and the auxiliary materials used also meet the national standard GB2760-2011 (the National Food Safety Standard for Food Additive Use). Thus, the solid beverage is safe to consume and good in taste, and has certain effects on the improvement of blood stasis constitution, and the production process thereof is suitable for industrial mass production.
US10893686B2 System and method for moving a dispenser from a closed mode into a dispensing mode for use with a mobile confectionary edifice or vehicle
The disclosure extends to methods, systems, and devices for producing a shaved ice or snow cone products and providing toppings thereto. The system may comprise an ice shaving or snow cone machine, a mobile edifice, and a topping dispenser attached to the mobile edifice.
US10893685B2 Chlorogenic acid-containing composition manufacturing method
Provided is a method of producing a chlorogenic acid-containing composition, including a step of subjecting coffee beans to column extraction using an aqueous solvent, in which the coffee beans include at least one selected from the group consisting of green coffee beans, decaffeinated green coffee beans, roasted coffee beans having an L value of 40 or more, and decaffeinated roasted coffee beans having an L value of 25 or more, and include at least one selected from the group consisting of unground coffee beans and ground coffee beans having an average particle size of 2.0 mm or more.
US10893680B2 Method and device for processing carcasses of livestock along the spine
A method for processing carcasses of livestock, comprises the processing steps of: positioning a hanging livestock carcass; making an incision along the spine of the positioned hanging livestock carcass; loosening the meat from opposite sides of the feather bones of the spine; and splitting the spine of the carcass. A device for processing carcasses of livestock is arranged for enabling the process steps.
US10893678B2 Food forming concept
The present invention relates to a food forming drum comprising a multitude of rows product cavities, each row comprising a multitude of product cavities, wherein the product cavities are provided as one or more at least partially porous members made from a porous material with interconnecting pores. The present invention further relates to a food forming apparatus comprising a food forming drum and a porous member. Additionally, the present invention relates to a movable unit to transport a drum and a method to change a drum or clean the food forming apparatus.
US10893677B2 Pest control composition
An insect control composition and related methods of preparation and use are disclosed. The composition includes a mixture of non-cannabis flour and an amount of cannabis seed flour effective to mitigate a population of insecta treated with the mixture.
US10893676B2 1-acetyl-3-phenyl urea compound, and use thereof
A compound represented by formula (1) is described: The compound has an excellent efficacy for controlling weeds, and is thus useful as an active ingredient for an agent for controlling weeds.
US10893675B2 Powder formulation containing insect repellent
The present invention relates to a powder formulation comprising at least one insect repellent and magnesium hydroxide carbonate, and to a process for the preparation of the formulation and to the use of the formulation for repelling insects.
US10893674B2 Efficient stabilizer in controlling self accelerated decomposition temperature of peroxycarboxylic acid compositions with mineral acids
Highly acidic, stabilized peroxycarboxylic acid compositions are disclosed as having both improved antimicrobial efficacy in comparison to conventional peroxyoctanoic acid and peroxyacetic acid compositions for sanitizing applications, and improved transport and shipping stability. In particular, low odor and low/no VOC compositions having dual functionality as both acid wash and sanitizing compositions are disclosed.
US10893673B2 Quaternary disinfectant composition with anionic scale inhibiting agent
The present invention relates to quaternary ammonium disinfecting cleaner compositions comprising a quaternary ammonium compound, an antimicrobial amine, and an anionic scale inhibitor. Beneficially, the compositions provide sanitizing efficacy without diminished performance and without scale formation when diluted with hard water. The compositions are suitable for inactivating and/or reducing infectious agents, particularly Norovirus, Adenovirus, and Polyomavirus.
US10893671B1 Device and system for rodent control and extermination
Systems, devices, and associated methods of manufacturing are described that provide a rodent extermination system for efficient rodent population control. An example rodent extermination system includes a vacuum unit configured to generate suction and an extermination chamber. The extermination chamber defines a first end attached to and in fluid communication with the vacuum unit and a second end in fluid communication with an external environment. The system also includes at least one presence sensor and at least two electrocution plates. The at least two electrocution plates are electrified such that the rodent is electrocuted via contact with the electrocution plates, and the vacuum unit generates suction such that the rodent is moved through the extermination chamber. The vacuum unit may comprise a kill plate into which the rodent is ejected at high velocity in order to induce cervical dislocation or blunt force trauma to the rodent.
US10893670B2 Animal trap
An animal trap having an enclosure body, a restraint, and a latching and triggering mechanism is provided. A method of using this animal trap is also provided.
US10893669B2 Determination of the requirements on plant protection agents
The present invention relates to the cultivation of crop plants using plant protection agents. Objects of the present invention are methods, a system and a computer program product for determining the partial-area-specific requirement of a crop plant for plant protection agents.
US10893663B2 Method for obtaining information about a farm animal
The invention relates to a method for obtaining information about a farm animal, wherein a device (a) is attached to the head region of an animal, said device containing at least one acceleration sensor by means of which recurring acceleration data is measured, wherein the acceleration data is evaluated using automatic data processing means, and, as an outcome of the evaluation, is indicative of the activities and/or conditions of the animal. The acquired acceleration data is evaluated in order to detect the swallowing processes carried out by the animal.
US10893661B2 Environmentally aware pet leash
In embodiments, the environmentally aware pet leash may restrain the movements of a pet and monitor environmental conditions during a walk. An infrared thermometer within the pet leash may be pointed towards a walking surface in front of the pet. The pet leash may display the pavement temperature of the walking surface, on an operator display and may alert the use to pavement temperatures that lie outside of predetermined range of temperatures. A laser point that is aligned to display a visible spot at the center of the area may show the user where the pavement temperature is being determined. The pet leash may also display and alert based upon data from a plurality of environmental sensors and a distance/route tracker and may report environmental conditions, alerts, distances, or routes to a remote computer using a transceiver.
US10893660B2 Length control system and method
A retractable leash device (e.g., for pets, children, or the like) having a length control system for limiting the extendable length of a main line is provided. The device includes a cover plate mounted on a wind-up spool and having at least one ridged channel that interacts with a length control switch during line extension to control the extendable length of the main line while simultaneously maintaining the retractability of the main line.
US10893658B2 Automatic water delivery apparatus
Water delivery apparatuses and associated methods that minimize the amount of time and preparation and/or maintenance work required for a user to supply water to one or more animals are disclosed. In an aspect, water delivery apparatuses and associated methods of use are disclosed that are configured to maintain a substantially consistent water quantity within at least one water reservoir that provides drinkable water to one or more animals. The substantially consistent water quantity may be maintained by configuring at least one float mechanism that comprises at least one sealing element to at least partially block at least one orifice associated with at least one water supply inlet connected to a continuous water supply once the water within the reservoir reaches a certain level, thereby slowing and/or stopping the incoming water flow. When the water later falls below that level, the float mechanism and its associated sealing element may also drop and the orifice of the water supply inlet may become unblocked, thereby allowing more water to enter the reservoir. In this way, a user may not be required to constantly refill or otherwise maintain a water container in order to provide water to one or more animals, thereby saving the user time.
US10893654B2 Soybean variety
The present invention is in the field of soybean variety CL1463825, CL1560023, CL1560457, CL1560517, CL1561938, CL1562168, CL1562319, CW1410004, CW1660237, EC1661076, EE1660540, and EW1660267 breeding and development. The present invention particularly relates to soybean varieties CL1463825, CL1560023, CL1560457, CL1560517, CL1561938, CL1562168, CL1562319, CW1410004, CW1660237, EC1661076, EE1660540, and EW1660267 and to the seed, cells, germplasm, plant parts, and progeny of each or any of these cultivars, and methods of using CL1463825, CL1560023, CL1560457, CL1560517, CL1561938, CL1562168, CL1562319, CW1410004, CW1660237, EC1661076, EE1660540, or EW1660267 in a breeding program.
US10893650B1 Systems and methods for controlling center pivot irrigation systems
An electronic device is described, including memory and a processor coupled to the memory. The processor is configured to receive center pivot irrigation system information corresponding to a center pivot irrigation system and to request map data. The processor is also configured to a user interface with a map of the center pivot irrigation system. The processor is further configured to receive an input via the user interface indicating an input point. The processor is additionally configured to render an alteration point marker at a first position, the alteration point marker representing an alteration point for the pivot, the alteration point corresponding to a first radial position of the pivot at which a change in operation of the pivot is set to occur. The processor is also configured to control the center pivot irrigation system to alter operation of the pivot at the first radial position.
US10893649B2 Bracing and blocking apparatus for a variety of uses
A panel assembly has a first panel formed of a wire grid and a second panel formed of a wire grid. The second panel is mechanically affixed to a side of the first panel. Each of the wire grids includes a first grid member, a second grid member, and a barrier layer interposed between the first and second grid members. A connector joins a side of the second panel to a side of the first panel. The barrier layer can be of a permeable or impermeable material. An edge protector can be applied over an edge of the first and second grid members.
US10893646B2 Plant framing apparatus
A plant framing apparatus that provides aesthetic appearance and overcome water evaporation issues includes a first frame section, a second frame section, a plurality of locking mechanisms, and a plant opening. The first frame section and the second frame section are attached to each other by the plurality of locking mechanisms so that the first frame section and the second frame section can surround a plant base. The overall profile of the plant opening is formed by an inner lateral wall of the first frame section and the second frame section so that the plant base can project through the plant framing apparatus. Furthermore, the plant framing apparatus can include an interchangeable watering system to overcome drought conditions of the plant and/or an interchangeable lighting system to improve the aesthetic appearance of the plant.
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