Document Document Title
US09273371B2 Manufacturing method of grain-oriented electrical steel sheet
A predetermined steel containing Te: 0.0005 mass % to 0.0050 mass % is heated to 1320° C. or lower to be subjected to hot rolling, and is subjected to annealing, cold rolling, decarburization annealing, and nitridation annealing, and thereby a decarburized nitrided steel sheet is obtained. Further, an annealing separating agent is applied on the surface of the decarburized nitrided steel sheet and finish annealing is performed, and thereby a glass coating film is formed. The N content of the decarburized nitrided steel sheet is set to 0.0150 mass % to 0.0250 mass % and the relationship of 2×[Te]+[N]≦0.0300 mass % is set to be established. Note that [Te] represents the Te content and [N] represents the N content.
US09273367B2 Optically induced cell lysis biochip
The present invention provides an optically induced cell lysis biochip, which comprises: an upper substrate made of a transparent, electrically conductive material; a lower substrate made of a transparent, electrically conductive material; a photoconductive layer formed under the lower surface of the upper substrate or on the upper surface of the lower substrate; and a chamber formed between the upper substrate and the lower substrate. When there is an electric potential difference between the upper and lower substrates, a light spot illuminated on the photoconductive layer can cause the impedance of the illuminated area to decrease, thereby causing the electric current to center on the illuminated area of the photoconductive layer. Further, the electric current flowing through the illuminated area can induce the cell lysis process of a target cell.
US09273366B2 Methods, compositions, and kits for determining human immunodeficiency virus (HIV)
The present invention relates to compositions, methods, and kits for determining the presence or absence of HIV in a sample, in particular for determining HIV-1 group M, HIV-1 group O, and/or HIV-2, in particular for simultaneous determining of HIV-1 group M, HIV-1 group O, and HIV-2.
US09273365B2 Method for detecting Chikungunya virus
Compositions, methods and kits for detecting Chikungunya viral nucleic acids. Particularly described are methods for detecting very low levels of the viral nucleic acids using nucleic acid amplification.
US09273358B2 Compositions and methods for detecting predisposition to a substance use disorder
The present invention provides screening kits, compositions, and diagnostic methods for determining whether a subject has a predisposition to, or likelihood of having, a substance use disorder by determining a nucleic acid methylation profile from a biological sample from the subject, wherein a given profile indicates that the subject has a predisposition to a substance use disorder.
US09273356B2 Methods and kits for linking polymorphic sequences to expanded repeat mutations
Methods and kits are provided for determining which single nucleotide polymorphism (“SNP”) variant of an allele of a heterozygous patient is on the same allele as a disease-causing mutation that is at a remote region of the gene's mRNA comprising a) an allele specific reverse transcription reaction using an allele specific primer which recognizes one SNP variant, wherein further the 3′ end of the primer is positioned at the SNP nucleotide position, and b) analysis of the resulting cDNA product from the reverse transcription reaction at the region of the mutation to determine the presence or absence of the mutation on this allele specific cDNA product, wherein the allele specific primer is shorter than about 20 nucleotides.
US09273348B2 Method and array for the replication and analysis of nucleic acids
The invention includes a method and array for replicating and analyzing one or a plurality of different target sequences in nucleic acid samples. The different reactions for replicating the target sequences occur simultaneously on an array with selectively heatable array elements with their reaction surfaces, some of which have been modified differently, and in the sample solution disposed thereabove. The target sequences are analyzed using molecular detection on reaction surfaces of said array that have been modified with probe strands. The target strands are replicated and analyzed simultaneously, successively, or alternately.
US09273347B2 Detection of RNA-interacting regions in DNA
The present invention provides methods and kits for detecting RNA-interacting regions in genomic DNA.
US09273341B2 Methods for treatment of bacterial infections
The peptidoglycan layer is a vital component of the bacterial cell wall, which comprises 4→3 and 3→3 transpeptide cross-linkages, the formation of which are catalyzed by D,D- and L,D-transpeptidases, respectively. Methods for the treatment of bacterial infections with agents that inhibit L,D-transpeptidases, either alone or in combination with D,D-transpeptidase inhibitors, are provided herein. Also provided are methods for the treatment of chronic stage tuberculosis with agents that inhibit enzyme with L,D-transpeptidase activity.
US09273339B2 Methods for identifying bacteria
The present invention provides methods for identifying bacteria by analysis of lipid A and/or lipoteichoic acid structure and/or mass spectrometry ionization patterns.
US09273335B2 Compositions comprising a polypeptide having cellulolytic enhancing activity and a quinone compound and uses thereof
The present invention relates to compositions comprising: a polypeptide having cellulolytic enhancing activity and a quinone compound. The present invention also relates to methods of using the compositions.
US09273331B2 Process for producing 3-hydroxybutyric acid or salt thereof
The invention provides a process for producing 3-hydroxybutyric acid or a salt thereof. The process includes (1) culturing one or more halophilic bacteria belonging to the genus Halomonas under aerobic conditions in a medium containing an inorganic salt and one or more organic carbon sources; (2) changing the culture conditions from aerobic culture to microaerobic culture, and culturing bacterial cells of the halophilic bacteria to produce 3-hydroxybutyric acid or a salt thereof in a culture medium; and (3) collecting the 3-hydroxybutyric acid or the salt thereof from the culture medium.
US09273327B2 Poxvirus expression system
There is provided a method for inserting a nucleic acid sequence that encodes a foreign peptide into a poxvirus genome, said method comprising: identifying in the poxvirus genome a poxvirus open reading frame wherein said open reading frame is characterized by an initial ATG start codon and wherein expression of said open reading frame is driven by an operably-linked poxvirus promoter located upstream of the open reading frame and wherein expression of said open reading frame provides a peptide that is non-essential to viability of the poxvirus; and inserting the nucleic acid sequence that encodes the foreign peptide at a position downstream of the poxvirus promoter; wherein following said insertion, (i) the nucleic acid that encodes the foreign peptide is operably-linked to the poxvirus promoter and expression of said nucleic acid is driven by said poxvirus promoter; and (ii) translation of the foreign peptide is initiated at an ATG start codon located at the same position as the ATG start codon of the poxvirus open reading frame. Also provided are a poxvirus vector and corresponding uses of the poxvirus vector in medicine.
US09273319B2 Molecular switches and methods for making and using the same
The invention provides molecular switches which couple external signals to functionality and to methods of making and using the same. The switches according to the invention can be used, for example, to regulate gene transcription, target drug delivery to specific cells, transport drugs intracellularly, control drug release, provide conditionally active proteins, perform metabolic engineering, and modulate cell signaling pathways. Libraries comprising the switches and expression vectors and host cells for expressing the switches are also provided.
US09273313B2 Activation of quiescent stem cells
Compositions and methods are provided for altering the activation of quiescent stem cells by modulating activity of the microRNA miR-489.
US09273308B2 Selection of compartmentalized screening method
The present invention provides novel microfluidic substrates and methods that are useful for performing biological, chemical and diagnostic assays. The substrates can include a plurality of electrically addressable, channel bearing fluidic modules integrally arranged such that a continuous channel is provided for flow of immiscible fluids.
US09273307B2 Global transcription machinery engineering
The invention relates to global transcription machinery engineering to produce altered cells having improved phenotypes.
US09273305B1 Cell-based composite materials with programmed structures and functions
The present invention is directed to the use of silicic acid to transform biological materials, including cellular architecture into inorganic materials to provide biocomposites (nanomaterials) with stabilized structure and function. In the present invention, there has been discovered a means to stabilize the structure and function of biological materials, including cells, biomolecules, peptides, proteins (especially including enzymes), lipids, lipid vesicles, polysaccharides, cytoskeletal filaments, tissue and organs with silicic acid such that these materials may be used as biocomposites. In many instances, these materials retain their original biological activity and may be used in harsh conditions which would otherwise destroy the integrity of the biological material. In certain instances, these biomaterials may be storage stable for long periods of time and reconstituted after storage to return the biological material back to its original form. In addition, by exposing an entire cell to form CSCs, the CSCs may function to provide a unique system to study enzymes or a cascade of enzymes which are otherwise unavailable.
US09273302B2 Histidyl-tRNA synthetases for treating autoimmune and inflammatory diseases
The present invention relates generally to compositions and methods comprising histidyl-tRNA synthetase polypeptides or other specific blocking agents for the treatment autoimmune diseases and other inflammatory diseases, including those related to Jo-1 antibodies.
US09273300B2 Methods and compositions for modulating sialic acid production and treating hereditary inclusion body myopathy
According to certain embodiments of the present invention, methods for modulating the production of sialic acid in a system are provided, which comprise providing the system with a wild-type GNE-encoding nucleic acid sequence. According to such embodiments, the system may comprise a cell, muscular tissue, or other desirable targets. Similarly, the present invention encompasses methods for producing wild-type GNE in a system that comprises a mutated endogenous GNE-encoding sequence. In other words, the present invention includes providing, for example, a cell or muscular tissue that harbors a mutated (defective) GNE-encoding sequence with a functional wild-type GNE encoding sequence.
US09273299B2 Isoprene synthase variants with improved solubility for production of isoprene
The present invention provides methods and compositions of variant polypeptides having isoprene synthase activity with improved solubility. In particular, the present invention provides isoprene synthase variant for increased isoprene production in recombinant host cells.
US09273297B2 Stabilization of alpha-amylases towards calcium depletion and acidic pH
The present invention relates to variants of a parent alpha-amylase, the variant having improved stability or activity at low calcium conditions or at low pH.
US09273296B2 Meganuclease variants cleaving a DNA target sequence from a glutamine synthetase gene and uses thereof
An I-CreI variant, wherein one of the two I-CreI monomers has at least two substitutions, one in each of the two functional subdomains of the LAGLIDADG core domain situated respectively from positions 28 to 40 and 44 to 77 of I-CreI, said variant being able to cleave a DNA target sequence from the glutamine synthetase gene. Use of said variant and derived products for improving expression system for the production of recombinant protein.
US09273295B2 Mutant citrobacter freundii phytase polypeptide
The present invention relates to enzymes and processes. In particular, there is described an isolated polypeptide comprising the amino acid sequence corresponding to Citrobacter freundii phytase or a homologue, a modified form, a functional equivalent or an effective fragment thereof. There is also described a host cell transformed or transfected with a nucleic acid encoding a bacterial phytase enzyme or a modified form as well as the use of such a phytase or modified form in food or animal feed.
US09273294B2 Targeted 2′-O-methylation of telomerase non-coding RNA
Processes and C/D box small nucleolar RNAs (snoRNAs) for altering telomerase activity and altering telomerase length are described. The processes of the invention involve the use of C/D box snoRNAs for targeted 2′-O-methylation modification of nucleotides in a pseudoknot region of the telomerase RNA. Depending on their position, the 2′-O-methylation modifications can cause an increase in telomerase activity and subsequent telomere lengthening or a decrease in telomerase activity and subsequent telomere shortening.
US09273291B2 Enzymatic alkene cleavage
The invention relates to an enzyme that comprises or includes a sequence according to SEQ. ID No. 1 or SEQ. ID No. 2, to a method for the production thereof, and to the use thereof as a catalyst in the oxidative cleavage of vinyl aromatics.
US09273289B2 Depletion of host cell components from live vector vaccines
It is desirable to produce live vaccines, which are highly attenuated and which do only contain minimal or no animal-derived components. The production of highly attenuated live viruses can be better achieved when using specifically designed cell lines as producer substrate as opposed to using less defined primary cells. However, live viruses, thus produced comprise undesirable components from the cell lines and cell culture. The present invention relates to methods of production and purification of live enveloped viruses, which are suitable for vaccination.
US09273287B2 Avian reoviridae and vaccines thereof
This invention relates to novel unique strains avian reoviridae that were isolated from severe cases of Runting Stunting Syndrome. The present invention also relates to the isolation and uses of novel unique avian reoviridae, diagnostic assays using nucleotide or amino acid specific components of such viruses, such as the sequence encoding Sigma C capsid protein and to vaccines that protect birds from diseases caused by such viruses.
US09273284B2 Method for generating potent dendritic cells
Highly potent dendritic cells are generated in vivo or ex vivo by exposing precursor cells to an effective dose of IL-32.
US09273280B2 Geobacter strains that use alternate organic compounds, methods of making, and methods of use thereof
In preferred embodiments, the present invention provides new isolated strains of a Geobacter species that are capable of using a carbon source that is selected from C3 to C12 organic compounds selected from pyruvate or metabolic precursors of pyruvate as an electron donor in metabolism and in subsequent energy production. The wild type strain of the microorganisms has been shown to be unable to use these C3 to C12 organic compounds as electron donors. The inventive strains of microorganisms are useful for improving bioremediation applications, including in situ bioremediation (including uranium bioremediation and halogenated solvent bioremediation), microbial fuel cells, power generation from small and large-scale waste facilities (e.g., biomass waste from dairy, agriculture, food processing, brewery, or vintner industries, etc.) using microbial fuel cells, and other applications of microbial fuel cells, including, but not limited to, improved electrical power supplies for environmental sensors, electronic devices, and electric vehicles.
US09273278B2 Large scale cell harvesting method for pack-bed culture device
A large scale cell harvesting method for a pack-bed culture device by providing cell growing space that is packed with a plurality of porous matrices and/or matrix means. When a cell detaching step at least comprising shaking or spinning the culture chamber is performed, the unoccupied space is large enough for the porous matrices collide to each other or to the culture chamber to generate momentum whereby the cells detach from the porous matrices to harvest the cells.
US09273274B2 Fabric conditioner sheet comprising a three-dimensional textured substrate comprising a thermoplastic film
A fabric conditioning sheet comprising a three-dimensional textured substrate formed from a thermoplastic film which has a substantially planar surface yet defines at least one three-dimensional macroscopic deformation extending away from said substantially planar surface; with a fabric conditioning compound being releasably affixed upon at least a portion of said three-dimensional textured substrate.
US09273273B2 Vehicle wash pod
A wash pod is provided that includes unit dose of anhydrous wash concentrate surfactant containing at least one cationic surfactant and at least one nonionic surfactant in water soluble hygroscopic polymeric package containing the concentrate. The film encapsulates the wash formula unit dose and dissolves when placed in a bucket of water while also being chemically and physically strong enough to hold a more preferred alkaline formula as well as to remain stable during storage is provided. A low volatile organic compound (VOC) car wash formula that is highly concentrated with a low water content and contains nonionic and cationic surfactants to promote cleaning, foaming and beading, while also containing a small amount of carnauba wax is also provided. The formulation of the car wash detergent provides a streak free low residue finish on a cleaned surface.
US09273271B2 Laundry detergent particles
The present invention provides a lenticular or disc coated detergent particle having perpendicular dimensions x, y and z, wherein x is from 1 to 2 mm, y is from 2 to 8 mm and z is from 2 to 8 mm, wherein the particle comprises: (i) from 40 to 90 wt % surfactant selected from anionic surfactant and non-ionic surfactant; (ii) from 1 to 40 wt % water soluble inorganic salts; and (iii) from 0.0001 to 0.5 wt % pigment, wherein the pigment is selected from organic and inorganic pigments, wherein the inorganic salts and the pigment are present on the detergent particle as a coating and the surfactant is present as a core.
US09273263B2 System for drying and torrefaction
A method for torrefaction of water containing cellulosic materials is performed in an inert atmosphere. The cellulosic material is cascaded through the apparatus between a plurality of rotatable trays vertically stacked within multiple processing zones. Steam being generated from heating of the cellulosic material is recycled back to the apparatus to provide an inert atmosphere. The steam may be superheated in a heat exchanger. Exhaust from the torrefaction zone of the apparatus has some moisture and other volatiles removed prior to being reheated in a burner. The heated exhaust is used in the heat exchanger to superheat the recycled steam.
US09273258B2 Methods of producing jet fuel from natural oil feedstocks through metathesis reactions
Methods are provided for producing a jet fuel composition from a feedstock including a natural oil. The methods include reacting the feedstock with a low-weight olefin in the presence of a metathesis catalyst under conditions sufficient to form a metathesized product. The methods further include hydrogenating the metathesized product under conditions sufficient to form a jet fuel composition.
US09273256B2 Increased production of fuels by integration of vacuum distillation with solvent deasphalting
Embodiments of the claimed invention are directed to methods and apparatuses that recycle unconverted oil fractions resulting from a hydrocracking unit, by feeding the unconverted oil fractions into a vacuum flasher and processing the fractions obtained therefrom.
US09273254B2 Amino acetals and ketals as hydrogen sulfide and mercaptan scavengers
The present invention generally relates to compositions and methods for scavenging hydrogen sulfide and/or mercaptans from fluids. More particularly, the invention relates to the use of amino acetal and ketal compounds as a hydrogen sulfide or a mercaptan scavenger for hydrocarbon fluids, particularly for natural gas, crude oil, field oil, fuel oil, naphtha, gasoline, kerosene, diesel, refinery gas, coal gas, tar, asphalt, coke gas, ammonia synthesis gas, gas from a sulfurization plant, or industrial gas streams.
US09273249B2 Systems and methods for controlling air distribution in a coke oven
The present technology is generally directed to systems and methods for controlling air distribution in a coke oven. In a particular embodiment, a coke oven air distribution system comprises an oven chamber having an oven floor configured to support a coal bed, a plurality of sidewalls extending upward from the oven floor, and an oven crown covering a top portion of the oven chamber. The air distribution system further includes an air inlet positioned above the oven floor and a distributor proximate to the inlet. The inlet is configured to introduce air into the oven chamber and the distributor is configured to at least one of preheat, redirect, or spread air within the oven chamber.
US09273248B2 Blue phase liquid crystal composite material and liquid crystal display containing the same
This disclosure relates to a blue phase liquid crystal composite material formed by photopolymerization of material components comprising a parent blue phase liquid crystal, a photo-polymerizable monomer, a photoinitiator, and inorganic nanoparticles; and to a liquid crystal display comprising the blue phase liquid crystal composite material. The blue phase liquid crystal composite material has a low driving voltage, no electro-optical hysteresis, and rapid response time to an electric field.
US09273247B2 Substituted amino alcohols as chiral dopants
The invention relates to the use of a substituted, chiral amino alcohol, comprising one or more structural units of the following formula (1), wherein the abbreviations A, Y, R1 and R3 to R5 have the following meanings: is a covalent bond or a hydrocarbon group, Y is a covalent bond or a hydrocarbon group that can have an oxygen atom at one of its ends through which it is bonded to R1, R1 is an aliphatic or heterocyclic or aromatic radical, the carbon chain of which may be interrupted by one or more B groups, R5 is selected from the group consisting of (a) aliphatic radicals, wherein individual carbon atoms may be replaced by oxygen atoms or carbonyl groups, and wherein the carbon chains of same radicals may be optionally interrupted by a B group, and (b) araliphatic, cycloaliphatic, aromatic and heterocyclic radicals, wherein the carbon chain can be interrupted by one or more B structural elements and/or by one or more D coupling groups, R3, R4 are hydrogen or aliphatic or araliphatic substituents, which are independent of one another, wherein the carbon chain can be interrupted by one or more B groups, B is selected from polymerizable or crosslinkable structural elements from the group comprising C1-C16-alkenyl, C1-C16-alkenyloxy, —C═C—, —CH═CH—COO—, —CH═CH—, —CX═CH—COO— with X═C1-C16-alkyl, and the trans-form of —OOC—CH═CH—COO—, and D is selected from —O—, —NH—, —N(CH3)—, —N(C2H5)—, —SO2—, —CO—, —COO—, —CH═CH—, —OCOO—, —OCH2—, CH═N, —CF2CF2—, as a chiral dopant in liquid crystal (mixtures), e.g., in electro-optical systems.
US09273246B2 Triphenylene derivative and use thereof
A triphenylene derivative of general formula (I) or general formula (II) which can be used as a component of liquid crystal medium and the use thereof are provided in the present invention. This compound can be used to form a negative discotic liquid crystal composition having a suitable temperature range of liquid crystal phase and a lower clearing point, which can be used in TFT liquid crystal display as an optical compensation film (cell) material.
US09273242B2 High density cement formulation to prevent gas migration problems
The invention provides a high density cement composition for preventing gas migration. The composition includes a silica sand component, a silica flour component, a hematite component, a manganese tetraoxide component, and an expansion additive component.
US09273241B2 High-resolution imaging system
The invention relates to a high-resolution imaging system for recording images of the same scene, that are sampled in a complementary manner. To this end, an image filter (2) is arranged in an intermediate focusing plane (PI), and a matrix (3) of microlenses is arranged at a distance from the image filter, with each microlens that is associated with an opening (O2) of the image filter. An image detection matrix (9) is then optically conjugated with the microlens matrix. The system also comprises a device for moving an intermediate image in relation to the image filter (2). Such an imaging system is especially suitable for recording high-resolution infrared images.
US09273235B2 Bonding material comprising coated silver nanoparticles and bonded object produced using same
A bonding material using silver nanoparticles considerably changes in coating-material property in response to a slight change in composition, and the stability thereof has been insufficient for large-amount application. A bonding material which uses silver nanoparticles, meets the requirements for mass printing, attains dimensional stability, and gives a smooth printed surface is provided. The bonding material includes silver nanoparticles which have at least an average primary particle diameter of 1 nm to 200 nm and have been coated with an organic substance having 8 or less carbon atoms, a dispersion medium, and a viscosity modifier composed of an organic substance, and has a viscosity (measured at a shear rate of 15.7 [1/s]) of 100 Pa·s or lower and a thixotropic ratio (measured at a shear rate of 3.1 [1/s]/measured at a shear rate of 15.7 [1/s]) of 4 or lower.
US09273231B2 Heat-activable adhesive tape particularly for bonding electronic components and conductor tracks
Heat activable adhesive tape for bonding electronic components and conductor tracks, with an adhesive composition having at least an acid-modified or acid anhydride-modified vinylaromatic block copolymer, and epoxide compound and a metal chelate.
US09273230B2 Hot melt assist waterborne adhesives and use thereof
A hot melt assist waterborne adhesive having high amplitude bead profile and higher heat resistance is provided. The hot melt assist waterborne adhesive includes an emulsion polymer, a preservative, a plurality of pre-expanded hollow microspheres and water. The hot melt assist waterborne adhesive is suitable as a partial or complete replacement to hot melt adhesives for use in converting paper and packaging process.
US09273226B2 Solvent-based coating compositions
Coating compositions are disclosed. In some embodiments, the coating compositions are used to coat substrates such as packaging materials and the like for the storage of food and beverages. The coating compositions can be prepared by reacting an epoxidized vegetable oil and a hydroxyl functional material in the presence of an acid catalyst to form a hydroxyl functional oil polyol, mixing the hydroxyl functional oil polyol (with or without epoxidized polybutadiene) with a functional polyolefin copolymer to form a mixture, reacting the mixture with an ethylenically unsaturated monomer component in the presence of an initiator to form a graft copolymer, and crosslinking the graft copolymer with a crosslinker to form the coating composition.
US09273225B2 Siloxane organic hybrid materials providing flexibility to epoxy-based coating compositions
Disclosed herein are epoxy-based compositions that include a polysiloxane flexibilizer and amino-functional alkoxysilane, which provides flexibility, hardness and gloss to such compositions and that are useful as coatings, adhesives, sealants and composites. Also disclosed are cured compositions and substrates coated with such epoxy-based compositions.
US09273221B2 Acrylic latex binder and method of preparation
The present invention relates to a process comprising contacting methyl methacrylate or styrene; a C1-C10-alkyl acrylate; and a polymerizable carboxylic acid monomer with a stable aqueous dispersion of first polymer particles, under emulsion polymerization conditions, to form a stable aqueous dispersion of second polymer particles. The first polymer particles have a Tg in the range of from −30° C. to 30° C., and the monomers have a calculated Tg in the range of 50° C. to 120° C. The present invention also relates to the dispersion of second polymer particles, which is useful as a binder to improve freeze-thaw stability in a coatings formulation.
US09273220B2 Polyelectrolyte complexes
The present invention relates to aqueous compositions of associative polyelectrolyte complexes (PECs), optionally containing surfactants, biocidal agents and/or oxidants, which can provide surface protection to treated articles including reduced soiling tendency, reduced cleaning effort and improved soil repellancy, as well as providing bacteriostatic properties to treated surfaces that thereby gain resistance to water, environmental exposure and microbial challenge. Treatment means and compositions are provided that employ associative polyelectrolyte complexes formed by combining a water soluble cationic first polyelectrolyte with a water soluble second polyelectrolyte bearing groups of opposite charge to the first polyelectrolyte under suitable mixing conditions where the one polyelectrolyte present in molar excess is added in the form of a first aqueous solution during a mixing step to a second aqueous solution comprising the oppositely charged polyelectrolyte present in molar deficiency. Also provided are means to form stable associative polyelectrolyte complexes in aqueous solutions having R values from about 0.10 to 20, including near stoichiometric R values approaching 1, being the ratio of charged groups present on the component polyelectrolytes employed.
US09273218B2 Coating for aqueous inkjet transfer
A coating composition for an image transfer member in an aqueous ink imaging system is disclosed that comprises a hydrophilic composition and a surfactant. The hydrophilic composition can be a starch-based composition.
US09273215B2 Adhesion promoter
Compositions useful for improving the adhesion of coating compositions, such as dielectric film-forming compositions, include a hydrolyzed poly(alkoxysilane). These compositions are useful in methods of improving the adhesion of coating compositions to a substrate.
US09273213B2 Special UV absorbers for curable UV-protective coatings
The present invention relates to organic UV absorbers which have two or more polymerizable acrylate or methacrylate groups in the molecule, to coating compositions comprising such UV absorbers, and also to coatings produced therefrom and to substrates coated therewith.
US09273204B2 Uncoated highly reflective impact-resistant injection-molded article and process for producing same
An uncoated, highly reflective, impact-resistant injection-molded article which comprises a rubber ingredient (A) and a thermoplastic resin (B), characterized in that (1) the rubber ingredient (A) has been dispersed in the thermoplastic resin (B), (2) the rubber ingredient (A) has a coefficient of linear expansion of 12.5×10−5 to 19×10−5/° C., (3) the surface of the injection-molded article has a reflected-image clarity of 60-100%, and (4) the injection-molded article has a notched Charpy impact strength of 5-60 kJ/m2.
US09273202B2 Adhesive composition and adhesive containing the same
It is an object of the present invention to provide adhesive compositions having excellent flexibility, rubber elasticity, mechanical properties, heat resistance and low-temperature properties.An adhesive composition of the invention includes 10 to 70 parts by weight of a soft polypropylene resin composition (X) which includes 40 to 98 wt % of a propylene copolymer (A) satisfying the following requirements (A1) to (A8) and 2 to 60 wt % of a crystalline isotactic polypropylene (B) satisfying the following requirements (B1) to (B3), and 30 to 90 parts by weight of a tackifier (C) (wherein the total of the component (X) and the component (C) is 100 parts by weight), wherein (A1) Shore A hardness: 20 to 90; (A2) the copolymer comprises a copolymer with C3 units at 51 to 90 mol %, C2 units at 7 to 24 mol % and C4-20 α-olefin units at 3 to 25 mol %; (A3) Mw/Mn: 1.2 to 3.5; (A4) mm: 85 to 99.9%; (A5) value B: 0.8 to 1.3; (A6) 2,1-insertion ratio: less than 1%; (A7) Tg: −10° C. to −50° C.; (A8) MFR (230° C.): 0.5 to 500 g/10 min; (B1) Tm: 100 to 175° C.; (B2) mmmm: 90 to 99.8%; (B3) MFR (230° C.): 0.1 to 100 g/10 min.
US09273200B2 Propylene polymer composition and molded article thereof
The present invention provides a propylene polymer molded article being high in tensile elongation and scratch resistance and a propylene polymer composition capable of affording such a molded article. Specifically, the present invention provides, in one embodiment thereof, a propylene polymer composition comprising a propylene polymer (A-1) that is a polymer having an intrinsic viscosity, as measured in tetralin at 135° C., of from 1.2 dl/g, inclusive, to 1.7 dl/g, exclusive, or a propylene polymer (A-2) that is a polymer having an intrinsic viscosity, as measured in tetralin at 135° C., of from 1.7 dl/g, inclusive, to 2.9 dl/g, inclusive, a propylene polymer (B) that is a polymer having an intrinsic viscosity, as measured in tetralin at 135° C., of from 0.5 dl/g, inclusive, to 1.1 dl/g, exclusive, and a nucleating agent.
US09273195B2 Tires comprising cellulose ester/elastomer compositions
A tire is provided comprising a cellulose ester/elastomer composition wherein the cellulose ester/elastomer comprises at least one cellulose ester, at least one elastomer, and at least one additive selected from the group consisting of at least one compatibilizer and at least one plasticizer.
US09273184B1 Synthesis of highly fluorinated amines for use in polymers and biomaterials
A method for forming a fluorinated compound includes a step of forming a sulfonate ester of a polyethylene glycol. The sulfonate ester is then reacted with a fluorinated diol in the presence of a base such that the polyethylene glycol is attached to one of the hydroxyl groups in the fluorinated diol. The other hydroxyl group in the fluorinated diol is reacted is converted into a leaving group and reacted with an number of nucleophiles. Complexes of the fluorinated compounds that as useful in Magnetic Resonance Imaging are also provided.
US09273182B2 Method for producing polyester compositions
A process of producing a polyester composition includes carrying out an esterification reaction of a dicarboxylic acid component with a diol component, and then carrying out a polycondensation reaction, wherein the diol component is added twice or more during a time from completion of the esterification reaction until beginning the polycondensation reaction, and alkali metal phosphate is added with an amount of COOH terminal groups of an esterification reactant being not more than 150 eq/ton.
US09273180B2 Polyols from biomass and polymeric products produced therefrom
Polyol compositions containing methane linkages derived from amino acids. The polyols are obtained from the reaction of the carbonate with the cadres in the amino acids. Individual amino acids or mixtures of amino acids that are prepared from the hydrolysis of the proteins can be used.
US09273179B2 Decomposable polymer
A decomposable polymer represented by General Formula (1): where X1 denotes a certain group; X2 denotes a certain group; R1 and R2 each independently denote a hydrogen atom, an alkyl group, an aromatic group, or an electron-withdrawing group; R3 and R4 each independently denote a hydrogen atom, an alkyl group, or an aromatic group, provide that R3, R4, or both are a hydrogen atom; R5 and R6 each independently denote a hydrogen atom, an alkyl group, or an aromatic group, provide that R5, R6, or both are a hydrogen atom; R7 and R8 each independently denote a hydrogen atom, an alkyl group, a halogen atom, or an aromatic group, provided that R7 and R8 may bond together to form a ring structure; R9 and R10 each independently denote a hydrogen atom, an alkyl group, or an aromatic group; n denotes a positive integer; and m denotes 0 or 1.
US09273178B2 Bio-based polyester resins
A polyester resin is described which includes bio-based, cyclohexadiene Diels-Alder reaction adduct monomer for use in toner for imaging devices.
US09273177B2 Curing agents providing a low ratio of thin-film cure time to gel time
The present disclosure relates to a curing agent for a curable resin which is a reaction product obtained from the reaction of a liquid epoxy and a polyamine component. The curing agent may be used as part of a two component curable system for the curing of unmodified epoxy resins.
US09273172B2 Method for producing a fluoroelastomer
The present invention provides a method for producing a fluoroelastomer using an emulsifier which is inexpensive and hardly remains in product polymers. The present invention is related to a method for producing a fluoroelastomer, wherein vinylidene fluoride and at least one fluoroolefin monomer other than vinylidene fluoride are copolymerized in the manner of an emulsion polymerization in the presence of an emulsifier represented by C5F11COOM, wherein M represents H, NH4 or an alkali metal.
US09273170B2 Polymers with improved toughness and ESCR for large-part blow molding applications
Disclosed herein are ethylene-based polymers having a density greater than 0.945 g/cm3, a high load melt index less than 25 g/10 min, a peak molecular weight ranging from 52,000 to 132,000 g/mol, and an environmental stress crack resistance of at least 250 hours. These polymers have the processability of chromium-based resins, but with improved impact strength and stress crack resistance, and can be used in large-part blow molding applications.
US09273166B2 Functionalized resins obtained via olefin metathesis
This invention relates to a reaction product obtained by contacting a polymer comprising units derived from dicyclopentadiene with a vinyl terminated macromonomer, a vinyl monomer or a vinylene monomer, in the presence of a metathesis catalyst, where the vinyl monomer or vinylene monomer is represented by the formula: wherein each X is, independently, —CO2R, —CONR1R2, CN, a C1 to a C20 alkyl group; R is a C1 to a C20 alkyl group or an aromatic group; each R1 and R2 is, independently, a hydrogen, a C1 to a C20 alkyl group, or an aromatic group; each R5 is, independently, a hydrogen atom or a C1 to a C40 alkyl group; each Ar is, independently, an aromatic group; and each n is, independently, from 0 to about 40.
US09273165B2 Lanthanide complex catalyst and polymerization method employing same
A novel class of lanthanide metal phenoxyimine complexes can be used as an ingredient of a catalyst system. The catalyst system can be used in polymerizations of ethylenically unsaturated hydrocarbon monomers.
US09273162B2 Process for monitoring the polymerization of ethylene or ethylene and comonomers in a tubular-reactor at high-pressures
A process for monitoring the polymerization of ethylene or ethylene and comonomers in the presence of free-radical polymerization initiator at pressures in the range of from 160 MPa to 350 MPa and temperatures in the range of from 100° C. to 350° C. in a tubular reactor with one or more reaction zones, which is equipped with cooling jackets for cooling the tubular reactor with a cooling medium, comprising a step of measuring as process parameters the temperature profile and the pressure of the reaction medium and the flow and temperature profile of the cooling medium along the reactor.
US09273158B2 Methods for production of hydrocarbons and oxygen-containing hyrdrocarbons
Environmentally friendly, energy efficient methods for making hydrocarbons, including oxygen containing hydrocarbons, linear or branched polymers, oligomers, waxes, small hydrocarbon molecules, fuels, coatings and starting materials/reactants to be used for making other hydrocarbons. A C1 carbon source, such as coal, natural gas, petroleum or biomass (including non-food biomass), is converted to the desired hydrocarbon. The reaction can be run in water, at room temperature and under atmospheric pressure. In some embodiments, the method comprises combining a) a C1 carbon source; b) water; c) an alkaline agent; and d) an alkyl Lewis acid in an amount effective to initiate or catalyze reaction of the components to form the hydrocarbon.
US09273152B2 Compositions comprising fibrous polypeptides and polysaccharides
Isolated polypeptides are disclosed comprising an amino acid sequence encoding a monomer of a fibrous polypeptide attached to a heterologous polysaccharide binding domain. Composites comprising same, methods of generating same and uses thereof are all disclosed.
US09273146B1 Anti-GCC antibody molecules and methods for use of same
Antibodies and antigen-binding fragments of antibodies that bind GCC are disclosed. The invention also provides therapeutic and diagnostic methods utilizing the antibodies and antigen-binding fragments provided herein.
US09273141B2 B cell maturation antigen (BCMA) binding proteins
The present invention concerns antigen binding proteins and fragments thereof which specifically bind B Cell Maturation Antigen (BCMA), particularly human BCMA (hBCMA) and which inhibit the binding of BAFF and APRIL to the BCMA receptor. Further disclosed are pharmaceutical compositions, screening and medical treatment methods.
US09273140B2 Antibody for detecting DNA damage in cells utilizing cell membrane surface antigen Ly6D
To provide a method for detecting cellular DNA damage by specifically recognizing molecules responsive to DNA strand breaks. A method for detecting DNA damage in cells, which comprises administering in vivo, to cells, an antibody against a cell membrane surface antigen that is expressed in cells undergoing DNA strand breaks to a greater extent than in cells not undergoing DNA strand breaks in an environment that causes DNA damage, and analyzing the expression status of the cell membrane surface antigen.
US09273138B2 Humanized forms of monoclonal antibodies to human GnRH receptor
Humanized forms of murine GHR106 monoclonal antibodies and methods of using them are described. Humanized GHR106 monoclonal antibodies have high affinity and specificity to the corresponding tumor-associated antigen, gonadotropin-releasing hormone (GnRH) receptor comparable to murine GHR106.
US09273137B2 FGFR-Fc fusion proteins and the use thereof
The present invention belongs to the field of biotechnology and relates to the treatment of diseases, especially the treatment of FGF overexpression-related diseases. Particularly, the present invention relates to FGFR-Fc fusion proteins and the use thereof in the treatment of angiogenesis regulation-related diseases. More particularly, the present invention relates to isolated soluble FGFR-Fc fusion proteins and their applications in manufacture of the medicament for the treatment of angiogenesis regulation-related diseases.
US09273136B2 Fully human anti-human NKG2D monoclonal antibodies
The invention relates to isolated fully human monoclonal antibodies having specificity for human NKG2D and compositions thereof. The invention further relates to methods for using such antibodies in treating diseases or conditions such as cancer, autoimmune disease, or infectious disease.
US09273133B2 Compositions and methods for the treatment and prevention of lens fibrotic diseases
Compositions and methods for treating fibrotic diseases are provided.
US09273131B2 Anti-bFGF humanized double-stranded antibody with stable disulfide bond, preparation method and application thereof
Disclosed are an anti-bFGF humanized double-stranded antibody with stable disulfide bond, the preparation method and the applications thereof. The amino acid sequence of the anti-bFGF humanized ds-Diabody is shown in SEQ ID NO.1. The nucleotide sequence of gene encoding the anti-bFGF humanized ds-Diabody is shown in SEQ ID NO.2. By site-directed mutation, two cysteine residues are introduced into VL and VH domain of anti-bFGF Diabody, thus introducing the disulfide bond and form ds-Diabody. It is shown by experiments that the obtained ds-Diabody has the following advantages: enhanced stability; better affinity when binding to the specific antigen bFGF; moderate relative molecular weight, good tumor targeting, more powerful in tumor tissue penetration, and higher blood clearance rate, showing a broad application prospects in the clinic diagnosis and tumor therapy.
US09273126B2 Humanized antibodies against the beta-amyloid peptide
The invention discloses an isolated antibody that selectively binds to the C-terminal part of Abeta and is humanized or fully human. The antibody of the invention is capable of preventing oligomerization of Abeta. Furthermore, a method of diagnosis comprising the steps of: (i) Labelling an antibody; (ii) Administering an effective dose of said antibody intranasally or systemically to a subject; and (iii) Detecting the concentration and/or presence of the labelled antibody in body parts of the subject is disclosed.
US09273124B2 Monoclonal antibodies that react with the capsule of Bacillus anthracis
The present disclosure relates to monoclonal antibodies that bind poly-γ-D-glutamic acid (γDPGA), which is present on the surface of Bacillus anthracis. The disclosure also provides chimeric forms of the monoclonal antibodies, humanized forms of the monoclonal antibodies, and fragments thereof, as well as nucleic acids encoding the antibodies and fragments thereof. Pharmaceutical compositions including such antibodies are also disclosed herein. The disclosure further provides prophylactic, therapeutic, and diagnostic methods of using the disclosed antibodies.
US09273118B2 Means and methods for producing high affinity antibodies
The invention provides means and methods for modulating the occurrence of somatic hypermutations in antibody producing plasmablast-like B-cells.
US09273117B2 Method for administering homeopathically potentized antibody
The invention provides for a method of treating neuropsychiatric disorders in a patient. The method comprises the step of administering to the patient a homeopathically potentized form of at least one antibody to an antigen capable of treating the neuropsychiatric disorders.
US09273110B2 Production of glycoproteins using manganese
Culture media comprising manganese and methods of culturing cells to improve sialylation and glycosylation of glycoproteins are provided.
US09273104B2 Methods for producing secreted polypeptides having biological activity
The present invention relates to methods for producing a polypeptide having biological activity, comprising: (a) cultivating a fungal host cell in a medium conducive for the production of the polypeptide, wherein the fungal host cell comprises a first polynucleotide encoding the polypeptide operably linked to a second polynucleotide encoding a variant signal peptide or a variant prepropeptide; and (b) isolating the secreted polypeptide having biological activity from the cultivation medium.
US09273103B2 Method for increasing ETEC CS6 antigen presentation on cell surface and products obtainable thereof
A method for increasing the presentation of ETEC CS6 antigen on cell surface, comprising the step of contacting cells expressing said antigen with an aqueous solution comprising 0.6-2.2 percent phenol by weight, such that the presentation of said antigen is increased by at least 100%. A method for the manufacture of a killed whole cell vaccine for immunization against CS6-expressing ETEC. Cells and vaccines obtainable by the above methods.
US09273102B2 Peptides derived from Campylobacter jejuni and their use in vaccination
Disclosed are polypeptides for Campylobacter jejuni that are useful as immunogenic agents for vaccine use. Also disclosed are nucleic acid fragments encoding the polypeptides as well as compositions, methods and molecular biology tools derived from or related to the proteins.
US09273101B2 Functionalized biomaterials for tissue regeneration
Functionalized self-assembling peptides suitable for obtaining hydrogels for use in a wide range of applications in the biomedical field, such as for the development of biomaterials for regenerative medicine and basic science research are described.
US09273100B2 Use of Galerina marginata genes and proteins for peptide production
The present invention relates to compositions and methods comprising genes and peptides associated with cyclic peptides and cyclic peptide production in mushrooms. In particular, the present invention relates to using genes and proteins from Galerina species encoding peptides specifically relating to amatoxins in addition to proteins involved with processing cyclic peptide toxins. In a preferred embodiment, the present invention also relates to methods for making small peptides and small cyclic peptides including peptides similar to amanitin. Further, the present inventions relate to providing kits for making small peptides.
US09273099B2 Stabilized alpha helical peptides and uses thereof
Novel polypeptides and methods of making and using the same are described herein. The polypeptides include cross-linking (“hydrocarbon stapling”) moieties to provide a tether between two amino acid moieties, which constrains the secondary structure of the polypeptide. The polypeptides described herein can be used to treat diseases characterized by excessive or inadequate cellular death.
US09273098B2 Lactam-bridged melanocortin receptor-specific peptides
Lactam-bridged melanocortin receptor-specific cyclic peptides of the formula where R1, R2, R3, R4, R5, R6, R7, R8 and R9 are as defined in the specification, compositions and formulations including the peptides of the foregoing formula, and methods of preventing, ameliorating or treating melanocortin receptor-mediated diseases, indications, conditions and syndromes, including obesity, modulation of feeding behavior, related metabolic syndrome, sexual dysfunction, male erectile dysfunction and female sexual dysfunction.
US09273095B2 Antibiotic peptide and preparation method therefor and application therefor
Disclosed are an antibiotic peptide and the like, having an amino acid sequence of Ac-Phe-Lys-Lys-Leu-Lys-Lys-Leu-Phe-Ser-Lys-Leu-Trp-Asn-Trp-Lys-NH2 (SEQ ID No:2). Also disclosed are a method of preparing the antibiotic peptide and the like, and the application thereof. The antibiotic peptide and the like synthesized by the solid phase synthetic technology according to the present invention can be used as a formulation against microbial infection and as alternate or adjuvant medicaments of antibiotics in the prior art.
US09273091B2 Processes for preparing tubulysins
Tubulysins are a series of naturally occurring cytotoxic agents that are of interest as anticancer therapeutic agents. Processes and intermediates useful for preparing naturally occurring and non-naturally occurring tubulysins and analogs and derivatives thereof are described.
US09273082B2 Substituted aliphanes, cyclophanes, heteraphanes, heterophanes, hetero-heteraphanes and metallocenes useful for treating HCV infections
The present disclosure provides substituted aliphanes, cyclophanes, heteraphanes, heterophanes, hetero-heteraphanes and metallocenes, of Formula I D-M-D  (Formula I) useful as antiviral agents. In certain embodiments disclosed herein M is a group —P-A-P— where A is Certain substituted aliphanes, cyclophanes, heteraphanes, heterophanes, hetero-heteraphanes and metallocenes disclosed herein are potent and/or selective inhibitors of viral replication, particularly Hepatitis C virus replication. Pharmaceutical compositions/and combinations containing one or more substituted aliphanes, cyclophanes, heteraphanes, heterophanes, hetero-heteraphanes and metallocenes and a pharmaceutically acceptable carrier are also provided by this disclosure. Methods for treating viral infections, including Hepatitis C viral infections are provided by the disclosure.
US09273080B2 Metal complexes
The present invention relates to metal complexes and to electronic devices, in particular organic electroluminescent devices, containing these metal complexes. M(L)n(L′)m (formula 1), where the compound of the general formula (1) contains a moiety M(L)n of the formula (2).
US09273077B2 Phosphorus derivatives as kinase inhibitors
The invention features compounds of the general formula: in which the variable groups are as defined herein, and to their preparation and use as protein kinase inhibitors.
US09273076B2 Compounds for nonsense suppression, and methods for their use
The present invention relates to methods, compounds, and compositions for treating or preventing diseases associated with nonsense mutations in an mRNA by administering the compounds or compositions of the present invention. More particularly, the present invention relates to methods, compounds, and compositions for suppressing premature translation termination associated with a nonsense mutation in an mRNA.
US09273074B2 Formylpyrrole-based heterocycles for nucleic acid attachment to supports
A compound has Formula I: A, B, C, D, W, X, Y, and Z are independently selected from hydrogen, optionally substituted C1-C6 alkyl, optionally substituted C1-C6 alkoxy, aryl, aldehyde, protected aldehyde, CH, N, O, S, null, and bond; Q is selected from aldehyde, protected aldehyde, and null, at least one of A, B, C, D, W, X, Y, Z, or Q is an aldehyde or protected aldehyde; the bonds between each of A-B, B-C, C-D, W-X, X-Y, and Y-Z are selected from single bond, double bond, triple bond, and no bond; L is a linker selected from a C1-C12 alkyl, aralkyl, and aryl, any of which is optionally substituted; one or more methylene unit (CH2) of the C1-C12 alkyl is optionally replaced by any combination of oxygen, carbonyl(C═O), and NH; and R1 and R2 are independently selected from —NR3R4, halogen, C1-C8 alkoxy, aralkoxy, alkenyloxy, alkynyloxy, and OCH2CH2CN; R3 and R4 are independently a C1-C4, straight chain or branched alkyl group.
US09273072B2 Method for producing organosilicon compounds which have amino groups
The invention relates to a method for producing amino-functional polyorganosiloxanes, wherein (A) organosiloxanes which contain Si—OH groups are reacted with (B) at least stoichiometric quantities of mono-alkoxy(amino-alkyl)silanes, with respect to the Si—OH groups, (C) in the presence of at least one acid as a catalyst.
US09273071B2 Zinc oxide complexes
Disclosed are compounds and methods of making said compounds comprising a zinc oxide molecule chemically bound to one or more molecules having an acidic hydrogen, such as an organic acid. The invention also provides compositions comprising such compounds and methods of preparing such compounds. The compounds of the invention may be provided in, for example, topical skin formulations, pharmaceutical compositions, or delivery systems for active ingredients.
US09273068B2 Substituted isoquinolines and phthalazines as inhibitors of phosphodiesterase type 10A
The present invention relates to novel compounds of the formula (I), wherein Het, A, Q, X1, X2, X3, R1 and R2 are defined in the specification, which are inhibitors of phosphodiesterase type 10A and to their use for the manufacture of a medicament and which thus are suitable for treating or controlling of medical disorders selected from neurological disorders and psychiatric disorders, for ameliorating the symptoms associated with such disorders and for reducing the risk of such disorders.
US09273067B2 Pyrazolopyrimidine macrocycles as inhibitors of human immunodeficiency virus replication
The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for making and using these compounds in the treatment of HIV infection.
US09273066B2 Forms of rifaximin and uses thereof
The present invention relates to Rifaximin polymorphic forms, to their use in medicinal preparations and to therapeutic methods using them.
US09273064B2 Benzodioxole or benzodioxepine heterocyclic compounds as phosphodiesterase inhibitors
Compounds of the general formula I wherein each of m and n is independently 0 or 1; R1 and R2, together with the carbon atom to which they are attached, form a heterocyclic ring comprising one or two heteroatoms selected from oxygen, sulfur, —S(O)— and —S(O)2—; R3 is —CHF2, —CF3, —OCHF2, —OCF3, —SCHF2 or —SCF3; X is a bond, —CH2—, or —NH—; A is aryl, cycloalkyl, cycloalkenyl, arylalkyl, heteroaryl, heteroarylalkyl, heterocycloalkyl or heterocycloalkenyl, optionally substituted with one or more, same or different substituents selected from R4; and R4 is hydrogen, amino, thioxo, alkyl, haloalkyl, hydroxyalkyl, alkoxy, haloalkoxy, halogen, oxo, thia, or hydroxy; or pharmaceutically acceptable salts, hydrates or solvates thereof, have been found to exhibit PDE4 inhibiting activity, and may therefore be useful in the treatment of inflammatory diseases and disorders.
US09273061B2 Compositions and methods for the treatment of chronic pain
The invention relates to the compounds of formula I and formula II or its pharmaceutical acceptable salts, as well as polymorphs, solvates, enantiomers, stereoisomers and hydrates thereof. The pharmaceutical compositions comprising an effective amount of compounds of formula I or formula II, and methods for treating chronic pain in a disease may be formulated for oral, buccal, rectal, topical, transdermal, transmucosal, intravenous, parenteral administration, syrup, or injection. Such compositions may be used to treatment of acute pain (such as post-operative pain), palliative care to alleviate the severe, chronic, disabling pain of terminal conditions such as cancer, and degenerative conditions such as rheumatoid arthritis, non-malignant chronic pain, chemotherapy induced pain, musculoskeletal pain, sciatica, radiculopathy pain, migraine, neuropathic pain, post herpetic neuralgia, neuralgia pain, multiple sclerosis, multiple sclerosis, restless legs syndrome (RLS), cluster headache, depression, fibromyalgia and amyotrophic lateral sclerosis (ALS).
US09273055B2 Tyrosine kinase inhibitors
The present disclosure relates to the field of tyrosine kinase enzyme inhibition, in particular anaplastic lymphoma kinase (ALK) inhibition using novel small molecules. Provided are compounds capable to modulate ALK activity, compositions that comprise the compounds, and methods of using the compounds for the treatment or prevention of diseases or conditions that are characterized by ALK activity or expression.
US09273053B2 Sulfur-containing heterocyclic derivative having Beta secretase inhibitory activity
The following compound is provided as an agent for treating a disease induced by production, secretion and/or deposition of amyloid β protein, for example, a compound represented by the formula: wherein Ry is halogeno lower alkyl; ring A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group, R1 is optionally substituted lower alkyl or the like, R2a and R2b are each independently hydrogen, optionally substituted lower alkyl or the like, R3a, R3b, R3c and R3d are each independently hydrogen, halogen, hydroxy, optionally substituted lower alkyl or the like, or a pharmaceutically acceptable salt thereof, or a solvate thereof.
US09273050B2 Cyclobutyl purine derivative, angiogenesis promoting agent, lumen formation promoting agent, neurocyte growth promoting agent, and drug
Provided is a compound having at least one selected from the group consisting of cell growth promoting activity, angiogenesis promoting activity, lumen formation promoting activity, cell migration promoting activity, and neurocyte growth promoting activity, which is a chemically stable low-molecular-weight substance that has high absorbability and can be supplied stably at a low cost because of its low molecular weight. A cyclobutyl purine derivative, a tautomer or stereoisomer thereof, or a salt, solvate, or hydrate thereof according to the present invention is a cyclobutyl purine derivative represented by the following general formula (1), a tautomer or stereoisomer thereof, or a salt, solvate, or hydrate thereof.
US09273049B2 Method for increasing the solubility of nevirapine
The invention provides a method for increasing the solubility of nevirapine, including the steps of rendering nevirapine in a gaseous phase; and rendering the gaseous phase in a relatively more soluble solid particulate form. The invention further provides for a crystalline Form-VI (36) of nevirapine having an X-ray diffraction pattern of (2-theta values in degrees) 9.2953, 11.2023, 12.7019, 12.9796, 13.5273, 15.4670, 17.2597, 19.1038, 19.7267, 21.1303, 22.9381, 25.5589, 26.4913, 27.2150, 27.7283, 29.7134, and 33.8343 degrees two theta. The invention further provides for the preparation of microspherical and/or nanospherical Form-V (34) and crystalline Form-VI (36) of nevirapine as well as novel dosage forms including parenteral-, inhalant-, transdermal- and oral dosage forms.
US09273048B2 Spirocyclic morphinans and their use
The application is directed to compounds of Formula I′-A and especially to compounds of Formula I-A and pharmaceutically acceptable salts and solvates thereof, wherein R1a-R5a, Y, Za are defined as set forth in the specification. The invention is also directed to use of compounds of Formula I′-A, and especially compounds of Formula I-A, to treat disorders responsive to the modulation of one or more opioid receptors, or as synthetic intermediates. Certain compounds of the present invention are especially useful for treating pain.
US09273043B2 TRPV1 antagonists including dihydroxy substituent and uses thereof
The disclosure relates to Compounds of Formula (I) and pharmaceutically acceptable derivatives thereof, where R1, R4, R8, R9, and m are as defined herein, compositions comprising an effective amount of a Compound of Formula (I) or a pharmaceutically acceptable derivative thereof, and methods for treating or preventing a condition such as pain, pain associated with osteoarthritis, osteoarthritis, UI, an ulcer, IBD, and IBS, comprising administering to an animal in need thereof an effective amount of a Compound of Formula (I) or a pharmaceutically acceptable derivative thereof.
US09273042B2 5-amino[1,4]thiazines as BACE 1 inhibitors
The present invention provides a compound of formula I having BACE1 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease.
US09273038B2 Solid forms of an ion channel modulator
Crystalline solid forms of the selective late sodium current inhibitor 4-(pyrimidin-2-ylmethyl)-7-(4-(trifluoromethoxy)phenyl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one (Compound I) were prepared and characterized in the solid state: Also provided are processes of manufacture and methods of using the crystalline forms.
US09273035B2 Diaryl and arylheteroaryl urea derivatives as modulators of the 5-HT2A serotonin receptor useful for the prophylaxis and treatment of disorders related thereto
The present invention relates to certain pyrazole derivatives of Formula (I) and pharmaceutical compositions thereof that modulate the activity of the 5-HT2A serotonin receptor. Compounds and pharmaceutical compositions thereof are directed to methods useful in the prophylaxis or treatment of platelet aggregation, coronary artery disease, myocardial infarction, transient ischemic attack, angina, stroke, atrial fibrillation, reducing the risk of blood clot formation, asthma or symptoms thereof, agitation or a symptom, behavioral disorders, drug induced psychosis, excitative psychosis, Gilles de la Tourette's syndrome, manic disorder, organic or NOS psychosis, psychotic disorder, psychosis, acute schizophrenia, chronic schizophrenia, NOS schizophrenia and related disorders, and sleep disorders, sleep disorders, diabetic-related disorders and the like.The present invention also relates to the method of prophylaxis or treatment of 5-HT2A serotonin receptor mediated disorders in combination with a dopamine D2 receptor antagonist such as haloperidol, administered separately or together.
US09273032B2 Photolabile compounds
The present invention describes photolabile compounds and methods for use of the compounds. The photolabile compounds have a photoreleasable ligand, which can be biologically active, and which is photoreleased from the compound upon exposure to light. In one embodiment, the light is visible light, which is not detrimental to the viability of biological samples, such as cells and tissues, in which the released organic molecule is bioactive and can have a therapeutic effect.
US09273030B2 Process for the preparation of benzimidazole derivatives and salts thereof
Provided are novel salts of benzimidazole derivatives, preferably salts of benzimidazole derivatives which are useful intermediates in the synthesis of pure 1-methyl-2-[N-[4-(N-n-hexyloxycarbonylamidino)phenyl]aminomethyl]benzimidazol-5-yl-carboxylicacid-N-(2-pyridyl)-N-(2-ethoxycarbonylethyl)amide and its salts.
US09273029B2 Pyridine-and pyrazine derivatives
Compounds of the formula (I) in which R, R1 and X have the meanings indicated in claim 1, are inhibitors of TBK1 and IKKε and can be employed, inter alia, for the treatment of cancer and inflammatory diseases
US09273028B2 Heterocyclic tyrosine kinase inhibitors
The present invention provides compounds useful as inhibitors of Tec family kinases, compositions thereof, and methods of using the same.
US09273019B2 Process and assembly for producing alkylene oxides and glycol ethers
There is provided a process for manipulating the amount of alkyl alcohol in a product stream, e.g., such as an alkylene oxide product stream. More particularly, and in contrast to conventional processes wherein substantially all of the alkyl alcohol must be separated and desirably recycled, in the present process, a greater amount of alkyl alcohol may be allowed to remain in a partially refined alkylene oxide product stream. The residual alkyl alcohol is subsequently substantially entirely reacted to form a downstream product, e.g., a glycol ether, which is more easily separated from the alkylene oxide product stream. Indeed, the amount of alkyl alcohol in the partially refined alkylene oxide product stream can be selected based upon the output of glycol ethers, if desired.
US09273012B2 Facile preparation of 4-substituted quinazolines and related heterocycles
A straightforward single step method for the preparation and/or production of substituted quinazolines is disclosed, wherein said quinazolines preferably contain one substituent at position 4, and may contain other functional groups at various positions, such as 5, 6, 7, and/or 8 of quinazolines. In addition, the extension of this new method leads to the formation of different type of heterocyclic aromatic compounds, that include but are not limited to perimidines, anthrapyrimidin-7-ones (also known as anthrapyrimidinones), anthra[1,9:5,10]dipyrimidines (also known as quinazoline[5,4-ef]perimidines) and benzo[e]-pyrimido[4,5,6-gh]pyrimidines.
US09273011B2 Substituted pyridazines for the treatment of pain
The invention provides compounds of formula I, (I) wherein: R represents a cyclic group selected from phenyl, heteroaryl, heterocyclyl and C 3-6 cycloalkyl; 10 wherein each cyclic group is optionally substituted with from 1 to 3 substituents selected from halo, C -6 alkyl optionally substituted with 1-3 halogen atoms, phenyl, C -6 alkoxy optionally substituted with 1-3 halogen atoms, cyano, heteroaryl 1a and heterocyclyl 1a; and wherein each cyclic group is optionally fused to a benzene ring or a 5- or 16-membered heteroaromatic or heterocyclic ring each containing from 1 to 3 heteroatoms (selected from N, O and S); and when the group is substituted the substitution may occur anywhere on the optionally fused ring system as a whole; and wherein heterocyclyl and heterocyclyl 1a may additionally be substituted with ═O; 20 X represents a bond or C -6 alkylene (which may be straight or branched); R 2 represents H or C -6 alkyl; R 3 represents H or C -6 alkyl; Y represents a bond or C -6 alkylene (which may be straight or branched, and optionally substituted with OH or CF 3); 2 R 4 represents a cyclic group selected from phenyl, heteroaryl 4, heterocyclyl 4 and C 3-6 cycloalkyl; wherein each cyclic group is optionally substituted with from 1 to 3 substituents selected from halo, C -6 alkyl optionally substituted with 1-3 halogen atoms, TET01063WO 4 phenyl, C -6 alkyl substituted with phenyl, C -6 alkoxy optionally substituted with -3 halogen atoms, cyano, heteroaryl 4a and heterocyclyl 4a; and wherein each cyclic group is optionally fused to benzene ring or a 5- or 6-membered heteroaromatic or heterocyclic ring each containing from 1 to 3 heteroatoms (selected from N, O and S); and when the group is substituted the substitution may occur anywhere on the optionally fused ring system as a whole; and wherein heterocyclyl 4 and heterocyclyl 4a may additionally be substituted with ═O; heteroaryl, heteroaryl 1a, heteroaryl 4 and heteroaryl 4a independently represent a 5- or 6-membered heteroaryl group containing from 1 to 3 heteroatoms (selected from N, O and 10 S); and heterocyclyl, heterocyclyl 1a, heterocyclyl 4 and heterocyclyl 4a independently represent a 5- or 6-membered heterocyclyl group containing from 1 to 3 heteroatoms (selected from N, O and S); and pharmaceutically acceptable salts and solvates thereof. 1 The compounds are useful as pharmaceuticals, particularly in the treatment of fibrotic diseases, cancer and pain.
US09273010B2 Process for bendamustine hydrochloride
The present invention provides a process for the preparation of 1H-benzimidazol-1-methyl-5-N,N-di(2-hydroxyethyl)-2-butanoic acid ethyl ester. The present invention also provides a process for the preparation of bendamustine hydrochloride. The present invention further provides a process for the purification of bendamustine hydrochloride.
US09273009B2 Tetrahydronaphthalene derivatives
This invention relates to novel tetrahydronaphthalene derivatives, and pharmaceutically acceptable salts thereof according to the following formulae, in one embodiment: as described herein. This invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering a selective T-type calcium channel blocker.
US09272994B1 Ginger metabolites and uses thereof
The present application generally relates to the use of metabolites of ginger and analogs thereof for the treatment and prevention of diseases, including but not limited to, cancer.
US09272990B2 Lysophosphatidic acid receptor antagonists and their use in the treatment fibrosis
Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.
US09272982B2 Method for preparing high-purity fesoterodine fumarate
A process is described for preparing fesoterodine fumarate comprising the salification reaction of fesoterodine with fumaric acid in an organic solvent, preferably a ketone, at a temperature not greater than 45° C. Such process allows obtaining products with high yields and purities, and in particular a product having a content of (2E)-4-[(3-(3-diisopropylamino-1-phenylpropyl)-4-(2-isobutyroyloxyphenyl)methoxy]-4-oxobut-2-enoic acid less than or equal to 0.15% by mole.
US09272975B2 Continuous process for the production of derivatives of saturated carboxylic acids
Provided is a continuous process for the oxidative cleavage of derivatives of unsaturated carboxylic acids for the production of saturated carboxylic acids and their derivatives which comprises the steps of: a) feeding to a first reactor at least a derivative of an unsaturated carboxylic acid, an oxidizing compound and a catalyst capable of catalyzing the oxidation reaction of the olefinic double bond to obtain an intermediate compound containing vicinal diols, and of b) feeding to a second reactor said intermediate compound, a compound containing oxygen and a catalyst capable of catalyzing the oxidation reaction of the vicinal diols to carboxylic groups, to obtain saturated monocarboxylic acids (i) and derivatives of saturated carboxylic acids with more than one acid function (ii); c) separating the saturated monocarboxylic acids (i) from the derivatives of carboxylic acids having more than one acid function (ii).
US09272969B2 Azeotropic compositions of 1,3,3-trichloro-1,1-difluoropropane and hydrogen fluoride
Provided are azeotropic or azeotrope-like mixtures of 1,3,3-trichloro-1,1-difluoro-propane (HCFC-242fa) and hydrogen fluoride. Such compositions are useful as a feed stock or intermediate in the production of HFC-245fa and HCFO-1233zd.
US09272965B2 Process for the conversion of alcohols to olefins
A process for the conversion of an alcohol to an olefin is disclosed. The process may include: contacting at least one C2 to C5 alcohol with an organic acid in the presence of an esterification catalyst to convert at least a portion of the at least one C2 to C5 alcohol and the organic acid to an ester; at least one of catalytically and thermally degrading the ester to form an organic acid and an olefin.
US09272962B2 Method for production of styrene from toluene and methanol
A process is disclosed for making styrene by converting methanol to formaldehyde in a reactor then reacting the formaldehyde with toluene to form styrene in a separate reactor.
US09272961B2 Production method of polyolefin, polyolefin and 1-hexene for linear low density polyethylene production raw material
The object of the present invention is to provide a production method for a polyolefin, in which catalyst activity is improved, and a polyolefin such as a linear low density polyethylene can advantageously be industrially produced. The present invention relates to a production method for a polyolefin, in which in producing a polyolefin by the polymerization reaction of an olefin using a catalyst, an organohalide is present in the reaction system in an amount of from 0.05 to 10 ppm by weight in terms of the halogen atom as a concentration in a raw material olefin, and 1-hexene for linear low density polyethylene production raw material, containing an organohalide in an amount of from 0.05 to 10 ppm by weight in terms of the halogen atom.
US09272956B2 Method for controlling aluminum titanate ceramic filter properties
A method for improving the thermo-mechanical properties of an aluminum-titanate composite, the composite including at least one of strontium-feldspar, mullite, cordierite, or a combination thereof, including: combining a glass source and an aluminum-titanate source into a batch composition; and firing the combined batch composite composition to produce the aluminum-titanate composite. Another method for improving the thermo-mechanical properties of the composite dips a fired composite article into phosphoric acid, and then anneal the dipped composite article. The resulting composites have a thin glass film situated between the ceramic granules of the composite, which can arrest microcrack propagation.
US09272954B2 Composition useful as mortar or coatings refractories
This invention relates to a composition comprising: ceramic refractory particulates made from alumina, one or more rare earth oxides, one or more oxides of a transition metal, the transition metal being Sc, Zn, Ga, Y, Cd, In, Sn, Tl, or a mixture of two or more thereof; an alumina and phosphate containing composition; and water. The composition is free of SiO2 or substantially free of SiO2, and is useful as a mortar or coating for molten aluminum or steel contact refractories.
US09272951B1 Low pH colloidal silica compositions for application to concrete
A composition for hardening concrete that has a pH of less than 10, and may have a pH of 8 or less. Thus, the hardening composition may be free of or substantially free of alkaline materials. The hardening composition is water-based and includes silica particles and stabilizer, which may be present on portions of the surfaces of the silica particles. The stabilizer may be aluminum-based (e.g., it may comprise alumina, etc.). In use, the hardening composition is applied to the surface of concrete, either alone, with curing compounds, or as part of a polishing process. Any residue that remains on the treated surface may simply be swept, blown, or sprayed away.
US09272950B2 Composite materials including ceramic particles and methods of forming the same
In some examples, a technique for forming a partially densified preform including ceramic particles may include mixing a densifying agent with metal oxide particles or metal oxide precursor to form a blended densifying agent, infiltrating the blended densifying agent in to a porous preform, pyrolyzing the infiltrated preform to convert the densifying agent to carbon and form a partially densified preform, and heat treating the partially densified preform to react at least some of the carbon with the metal oxide particles to form ceramic particles. Composite materials formed from porous preforms in which a blended densifying agent is disposed in pores of the preform are also described.
US09272943B2 Medium temperature solid fuel cell glass packaging material
A medium temperature solid oxide fuel cell glass packaging material is provided. The glass packaging material may include a glass main body made of SiO2, Al2O3, Y2O3 and ZnO, and at least one glass modifier added into the glass main body. Glass transition temperature ranges from 700 to 900 degrees Celsius. The glass modifier may be rare earth elements or transitory elements. The added glass modifier may adjust the glass transition temperature and the thermal expansion coefficient, and improve the bonding characteristics of the glass packaging material, so as to allow the manufactured glass packaging material to be applicable in SOFC application temperature range from 500 to 800 degrees Celsius.
US09272939B2 Dead plate arrangement
A dead plate arrangement for a glass forming machine is characterized by a housing (33) which is bordered on the upper side by a dead plate (1) which is divided into fields (16, 16′, 16″) intended for putting hollow glass articles to be cooled thereon, wherein to each field, a dynamic pressure chamber (3) is allocated which is connected to a supply air chamber (4) via a valve (9), and wherein the supply air chamber (4) is connected to a cooling air supply via a valve (5). The valves (5, 9) are continuously controllable between an opening position and a closed position so that the pressure can be set for each of the dynamic pressure chambers (3), and therefore the cooling capacity of each of the fields (16, 16′, 16″) can be set individually depending on the properties of the hollow glass article to be cooled. In connection with database-supported setpoint values for article-specific dimensioning of the cooling air flows of each field, an individual cooling capacity according to demand can be implemented which is adapted to the respective hollow glass article.
US09272936B2 Waste treatment process
A process for treating waste includes reacting an organic feedstock in a reactor. The organic feedstock is part of a reaction mixture that includes a first oxidizing acid (e.g., sulfuric acid) and nitric acid. The weight ratio of solids in the organic feedstock to the total of the first oxidizing acid and the nitric acid is at least 0.2. The weight ratio of solids in the organic feedstock to the first oxidizing acid is at least 0.3. The weight ratio of solids in the organic feedstock to the nitric acid is at least 0.5.
US09272935B2 Treatment of waste products with anaerobic digestion
A waste stream is treated by anaerobic digestion. A process is described involves a step of separating solids from digestate, and returning separated solids to a digester. Optionally, there may be a step of solids separation in which larger solids are removed from the digester. A process and apparatus are described for treating waste sludge from a wastewater treatment plant in an anaerobic digester. Feed sludge is thickened or solids are separated from digestate and returned to the digester. Additional co-digestion waste may be added to the digester. The process and apparatus may be used in a retrofit of an existing wastewater treatment plant.
US09272934B2 Removal of selenium from coal mining runoff water
Overburden from surface coal mining in many regions can produce a rain runoff laden with selenium, in the selenate form. This occurs from exposed selenium-containing rocks in the overburden, from which selenate is leached out by the nearly-pure rainwater. The selenium-containing runoff water is caught in ponds. Remediation of the pond water to remove selenate down to permissible levels for discharge to lakes and streams is performed by treatment with sulfur-modified iron (SMI) in a contact bed of an upflow reactor vessel. After a prefiltering step, the pond water is pH-adjusted as needed and pumped through the SMI reactor. The treated water can then be run through an oxidation tank and filtered to remove iron. For extending effectiveness and life of the SMI the contact bed is periodically “fluffed” with a high-velocity upflow of water through the bed, expanding and loosening the contact bed to prevent or break up compacting of the SMI medium.
US09272933B2 Bio-augmentation composition and use thereof for improving efficiency of effluent treatment in hydrocarbon processing plant
The present invention provides a bio-augmentation composition for improving the hydrocarbon degradation efficiency of effluent treatment plant for hydrocarbon degradation in wastewater generated from hydrocarbon processing industry and a method thereof. The composition comprises a synergistic combination of selective microorganisms to develop a consortium enabling effective degradation of hydrocarbons present in wastewater and converting thereof into harmless and environment friendly substances. The invention also provides for the said microorganisms and their isolations.
US09272932B2 Method for breakdown of toxic organic compounds contained in wastewaters and/or waste gases
A method is disclosed for breaking down toxic organic compounds contained in wastewaters and/or waste gases, in which the wastewaters and/or waste gases loaded with toxic organic compounds are first passed into an aqueous basic alkali/alkaline earth solution/suspension bath for destabilization of the toxic organic compounds and then the solution/suspension bath containing the destabilized toxic organic compounds is fed in ascending fashion into a capillary mass arranged above the bath, consisting of a mixture of pulps and peat mixed with bentonite, zeolite and/or lime with a particle size <200 μm.
US09272930B2 Portable renewable energy microgeneration system
A portable renewable energy microgeneration system is disclosed. The system comprises a plurality of first holding tanks that are configured to perform at least one of pasteurization and thermophilic anaerobic digestion on waste, a second holding tank that has a volume greater than each of the plurality of small holding tanks individually and that is configured to perform mesophilic anaerobic digestion on the waste after at least one of pasteurization and thermophilic anaerobic digestion is performed, and a controller configured to automatically control the flow of the waste between the plurality of small holding tanks and the second holding tank as required to facilitate mesophilic anaerobic digestion in the second holding tank. The plurality of first holding tanks and the second holding tank are configured to be transported to a site assembled and placed in fluid communication with each other at the site.
US09272929B1 Bioremediation separation system and method for human waste
A system and method for separating human waste and converting urine into potable water for drinking and use in a hand washing station (165). In one aspect a commode (100), a three-way valve (110) at the outlet of the commode, a urine reactants tank (145), a storage container (160), a pump (170), and a spigot (175) are used. A user turns an actuator (111) on the valve in one direction to direct feces and feces-plus-urine into a reactants tank for feces, and in another direction to direct urine into the urine reactants tank. The urine reactants tank contains a plurality of baffles (210) separating the tank into chambers. A first chamber contains algae and microorganisms supplied by a seed (150). These organisms absorb nutrients from the urine as they grow into a mass (152). A last chamber contains only purified water that flows from the tank into the storage container from which it can be pumped to the spigot.
US09272927B2 Method for preventing growth of microorganisms, and a combination for the prevention of microbial growth
According to the invention, a method for the prevention of microbial growth in process waters is provided, wherein first a peracid compound, and thereafter a halogenated dialkyl hydantoin are dosed into said process water. Further, according to the invention, a combination for the prevention of microbial growth is provided, said combination comprising compounds to be dosed separately, said compounds being a peracid compound to be dosed first, and a halogenated dialkyl hydantoin to be dosed after the peracid compound, the weight ratio of the peracid compound to the halogenated dialkyl hydantoin being at least 2:1, wherein the amount of the peracid compound is calculated as active agent, while the amount of halogenated dialkyl hydantoin is calculated as active chlorine.
US09272922B2 Inorganic iodide, production method thereof, and production system thereof
According to a method for producing an inorganic iodide in accordance with the present invention, it is possible to efficiently produce a highly pure inorganic iodide by reacting a hydrogen iodide gas with an inorganic base compound by bringing the hydrogen iodide gas into contact with the inorganic base compound. As such, it is possible to provide a simple and efficient method for producing an inorganic iodide.
US09272919B2 Hydrothermal synthesis of zeolites or zeolite-like materials using modified mixed hydroxides
This invention relates to a process for producing aluminum silicates in the form of zeolite L, as well as the intermediate and end products of this process. The invention further relates to the use of these aluminum silicates for the conversion or adsorption of hydrocarbons.
US09272914B2 -NH- terminated silicon surface and a method for its preparation
A uniform Si—NH—Si terminated Si(111) surface is formed by contacting a chlorine-terminated silicon surface with ammonia and a solvent such as an ether.
US09272912B2 Process and system for producing commercial quality carbon dioxide from recausticizing process calcium carbonates
The invention features methods and systems for recovering carbon dioxide, for producing commercial quality carbon dioxide (CO2) of 90% to +99% purity using, wet calcium carbonate lime mud produced in a recausticizing process that also produces caustic soda, for instance, Kraft paper pulp mill lime mud (a.k.a., “lime mud”) as a feedstock to a multi-stage lime mud calcination process. This process may be fueled with low, or negative cost “carbon-neutral” fuels such as waste water treatment plant (WWTP) sludge, biomass, precipitated lignins, coal, or other low cost solid fuels. High reactivity, high-quality calcined lime mud (a.k.a. re-burned lime, or calcine), required in the Kraft paper pulp mill's recausticizing process is also produced, and superheated high pressure steam and hot boiler feed-water is generated and exported to the mill's steam distribution and generation system as well as hot process water for use in the mill's manufacturing operation. The system for calcining calcium carbonate lime mud produced from a recausticizing manufacturing operation and converting it to calcined lime mud and CO2 comprises a calciner and a combustor linked by a moving media heat transfer (MMHT) system or apparatus. The MMHT system or apparatus thermally links separate fluid bed combustion (exothermic) and calcination (endothermic) stages with a solid particulate media. The system further comprises a flash dryer or spray dryer that utilizes exhausted enthalpy from the calcination stage.
US09272907B1 Ozone generator with a disposable emitter cartridge
An ozone generator with a disposable emitter cartridge preferably includes two emitter cartridges, a protective housing, a high voltage generation circuit and a power supply. The disposable emitter cartridge preferably includes an anode element, a cathode element and an insulating spacer. The anode element includes a plurality of emitter projections. The cathode element includes a base plate with a plurality of openings. The anode element is attached to one side of the insulating spacer and the cathode element is attached to an opposing side. The protective housing preferably includes a base portion, an emitter housing and a pair of vent caps. The two emitter cartridges are removable retained on the base portion. The power supply supplies electrical power to the high voltage circuit. The high voltage circuit supplies high voltage to the two emitter cartridges. Electrical current arcs from the plurality emitter projections to the plurality of openings.
US09272904B2 Process and burner for producing synthesis gas
This invention relates to the production of synthesis gas by partial oxidation of liquid or gaseous, carbonaceous fuel in the presence of an oxygen-containing oxidant, wherein the fuel, the oxidant and a moderator are separately supplied to a burner and wherein the fuel and the moderator are mixed in a mixing chamber of the burner, before they are brought in contact with the oxidant. To reduce the load of the burner in particular during operation with transient conditions, the oxidant is centrally introduced through an outlet opening of the burner into a combustion chamber and the mixture of fuel and moderator is introduced through the outlet opening into the combustion chamber concentrically around the oxidant.
US09272903B2 Method for electrodepositing copper nanoparticles
A method for electrodepositing copper nanoparticles includes the steps of a) providing a reaction system having an electrolyte solution, a conductive nitride film used as a working electrode and immersed in the electrolyte solution, a copper metal or a copper alloy used as an auxiliary electrode and immersed in the electrolyte solution, and a reference electrode immersed in the electrolyte solution; and b) applying a pulse voltage to the reaction system to form copper nanoparticles on a surface of the conductive nitride film.
US09272900B2 Nanostructures and methods of making the same
A nanostructure includes a highly conductive microcrystalline layer, a bipolar nanowire, and another layer (18, 30). The highly conductive microcrystalline layer includes a microcrystalline material and a metal. The bipolar nanowire has one end attached to the highly conductive microcrystalline layer and another end attached to the other layer.
US09272898B2 Electric device and method of manufacturing the same
There is provided an electric device including a base member, a beam elastically deformable to bend upward and having an outline partially defined by a slit formed in the base member, a conductive pattern provided on a top surface of the beam, a contact electrode provided above the conductive pattern, the contact electrode coming into contact with the conductive pattern, and a bridge electrode elastically deformable, the bridge electrode connecting the conductive pattern and a portion of the base member outside the outline.
US09272897B2 Portable transportable storage unit for dispensing a fuel additive
A portable storage unit for a fuel additive such as DEF comprising: a housing including a tray support and a cover; a container disposed in the lower area for containing a fluid; a first heating element disposed between an inner wall of the housing and the outer wall of the container; a fluid pump removable attached to the tray for pumping fluid from the container to a nozzle and for being removed from the tray to pump fluid from an external fluid source into the container; an intake hose connected to a coupler providing fluid communications between the container and the fluid pump.
US09272896B2 Labels, containers, system and methods for providing reagents
The invention relates to systems and methods for marketing and using products such as liquid materials, especially liquid reagents for use in microbiological and cellular biological laboratory settings include the use of unique color and simple numeric or alphanumeric identifiers to quickly and easily identify any product from a catalog list of products. Methods of marketing, advertising and producing such products are also disclosed. Particular embodiments include products, product packaging and product labeling. The invention also relates to collars and sleeves for containers, as well as related methods of use.
US09272895B2 Apparatus for storing and dispensing wine
An apparatus for storing and dispensing a fluid from a flexible portable fluid container. The apparatus includes a bottom surface and at least one sidewall that defining a cavity configured to receive a flexible portable fluid container. A support member extends from the bottom surface of the body into the cavity to help support the flexible portable fluid container. An extruding member extends outwardly from the outside portion of the sidewall and defines a channel that extends from the inside portion of the sidewall through the extruding member. The channel is sized to receive the spout of the flexible portable fluid container.
US09272892B2 Enhanced heat transfer to water
A beverage dispensing apparatus which includes a tank, a liquid inlet and a fluid dispensing system which includes a dispensing fluid conduit having a helical portion at least substantially vertically oriented within the interior volume of the tank. The beverage dispensing apparatus also includes a fluid circulating system that includes at least one fluid circulation conduit having an inlet portion positioned proximate the bottom portion of the tank and at least one outlet. A fluid cycling device is also included in the beverage dispensing apparatus and is configured to move fluid from the bottom portion of the tank to the fluid circulation conduit. The at least one outlet is configured to produce a fluid flow tangential to the orientation of the dispensing fluid conduit configuration. Evaporator coils extend around a perimeter of the tank's exterior sidewall surface and are configured to chill the fluid within the tank.
US09272890B2 Corkscrew assembly for use with a power tool
A corkscrew assembly includes a housing a worm screw assembly, a first gripper, and a second gripper. The housing defines (i) a first opening configured to receive a neck of a bottle, (ii) a second opening, and (iii) an interior space interposed between the first opening and the second opening. The housing includes a sidewall extending from the first opening to the second opening. The sidewall defines a first gripper passage and a second gripper passage. The interior space is interposed between the first gripper passage and the second gripper passage. The worm screw assembly is rotatable in relation to the housing and includes (i) a worm screw member having a pointed first end portion and a second opposite end portion and (ii) a drive member fixed in relation to the second opposite end portion.
US09272880B2 Elevator system including control electronics supported on an elevator machine support
An exemplary mounting arrangement for components of an elevator system comprises a machine support that is configured to support a load associated with an elevator machine. A support for control electronics that operate the elevator machine is connected to the machine support.
US09272877B2 Operation device for an elevator that includes an elevator access restriction device
Provided is an operation device for an elevator, which is capable of improving an operation efficiency of the elevator. The operation device includes: a landing destination-floor reservation device for storing, by input of personal-authentication information and destination-floor information thereto, the personal-authentication information to register a destination floor for a car; a car control device for raising and lowering the car based on information from the landing destination-floor reservation device; and a user restriction device to which personal-authentication information is input, for checking the input personal-authentication information against the personal-authentication information input to the landing destination-floor reservation device to restrict boarding of a user on the car.
US09272876B2 Cable retractor
A cable retractor for releasing and retracting an application cable. a cable retractor comprises a base; a spool having sides, the spool rotatably secured to the base to permit the application cable to be wrapped around the spool; a mandrel disposed concentrically within the spool, the mandrel being rotationally secured to the base to prevent axial rotation of the mandrel relative to the base; and the mandrel further having a recessed groove running lengthwise, and an internal cable having an outer connector and inner connector, the outer connector being connected through the spool to one end of the application cable, and the inner connector being exposed at one end of the mandrel from within the recessed groove.
US09272873B2 Printing press, folder, and methods of operation
Systems and methods for allowing existing rotary printing press units to produce smaller pages at a faster rate of speed without having to replace the press unit. Specifically, the systems and methods relate to retrofitting an existing press unit to produce three pages of material in each full rotation instead of the traditional two pages.
US09272871B2 Clamping device for a shaft and method for clamping same
A device and a method for holding a shaft, preferably a winding shaft, hold the shaft in a clamping jaw. A lever, which is rotationally supported about a first axis, is moved in reference to the shaft.
US09272869B2 Paper sheet processing apparatus
A paper sheet processing apparatus 1 for performing processes on paper sheets while conveying the paper sheets, being equipped with an apparatus body 10, processing means 3 for performing predetermined processes on the paper sheets, a control section 5 for controlling the operation of the paper sheet processing apparatus 1, an input section 6 to which a paper sheet processing condition is input, and a display section 7 for displaying the operation information of the paper sheet processing apparatus 1, wherein the processing means 3 is configured so that the processing pattern for the paper sheets can be changed, and the control section 5 obtains processing means setting information, serving as the processing pattern of the processing means 3, for achieving the processing condition having been input to the input section 6 and displays the processing means setting information on the display section 7.
US09272868B2 Document reading device
A document reading device is capable of facilitating attachment/detachment of a reading unit provided inside a U-shaped document conveying path formed in a document conveying device. The document reading device includes a U-shaped document conveying path extending from a sheet supply tray to a sheet discharge tray through a reading section and a reading unit disposed inside the U-shaped document conveying path, a downstream part of the sheet supply tray on which a document is placed and a guide member provided upstream of the document conveying path to continue from the sheet supply tray and is arranged to be attachable/detachable with respect to the sheet supply tray or document conveying path. The reading unit is removable from inside the U-shaped document conveying path through an opening through which the downstream part of the sheet supply tray and guide member of the document conveying path are removed.
US09272861B2 Sheet feeding unit and image forming apparatus
A sheet feeding unit includes a supporting member configured to rotatably support a rotary feeding member, a first retaining member configured to push the supporting member upward from the underside to retain the rotary feeding member at a waiting position, and a second retaining member protruding on the underside of the supporting member when the first retaining member retains the supporting member. The retention of the supporting member by the first retaining member is released in association with the mounting of a sheet storage portion in the mounting position, and then the retention of the supporting member by the second retaining member is released.
US09272859B2 Supply apparatus, method for supplying print medium, and printing apparatus
A supply apparatus including: a supply member that contacts a print medium and feeds out the print medium; a drive transmission unit configured to transmit rotation of a drive shaft to the supply member; and an arm member that supports the supply member and the drive transmission unit and rotates around a predetermined axis, wherein a contacting position between the supply member and the print medium is switched to any position of an upstream side or a downstream side in the feeding-out direction depending on a rotating position of the arm member.
US09272857B2 Sheet stacking apparatus, sheet feeding apparatus, and image forming apparatus
A sheet stacking apparatus includes a base member, a sheet stacking portion on which sheets are stacked, and a biasing portion configured to bias the sheet stacking portion.The sheet stacking portion is swingably supported by the base member, and the biasing portion biases the sheet stacking portion such that a swing angle is reduced.
US09272851B2 Minimization of drive tests for uplink link coverage
A method of using additional uplink measurements for MDT UL coverage is provided. A base station (eNodeB) establishes a radio resource control (RRC) connection with a user equipment (UE) in a mobile communication network. The eNodeB and the UE are configured for Minimization of Drive Test (MDT). The eNodeB receives a Power Headroom Report (PRH) corresponds to a Physical Uplink Shared Channel (PUSCH) from the UE, and forwards the PHR to an MDT server. The eNodeB performs uplink measurement of a Demodulation Reference Signal (DM-RS) allocated in the PUSCH. The uplink measurement also involves measuring an uplink Received Interference Power (RIP) associated with the PUSCH. The eNodeB then reports uplink measurement results to the MDT server. The MDT server is able to determine uplink coverage based on the PHR and the uplink measurement results.
US09272849B2 Cup feeder
A column of cups guided by their rims in elongated slots is spaced into desired cup pitch by one or more linear stars from which the cups can be transferred for packaging. The linear stars have lugs engaging and spacing the cups. In another aspect of the invention, cups are manipulated into patterns for final grouping and packaging and by a plurality of cup orienting pickers engaging, inverting and re-orienting the cups. In one final packaged cup group of two or more layers, alternating cups in each layer are inverted and a top lid of a cup in an upper layer is disposed on a top lid of a cup in a bottom layer, while a bottom of a cup in an upper layer is disposed on a bottom of a cup in a lower layer, and in an alternating pattern.
US09272848B2 Carrying device and controlling method
A carrying device includes a rack and a platform. The platform that loads goods, is moveably arranged on a handle of the rack. The carrying device further includes a sensor that detects the goods loaded on the platform, a motor that is connected to the platform, and a controlling unit that controls the motor drive the platform to move relative to the handle with a predetermined distance, according to whether the sensor detects the goods loaded on the platform.
US09272842B1 Modular garbage collection apparatus
This invention provides an apparatus for identifying and sorting part of recycling plastic bottles and aluminum cans. The invention eases the process of sorting recyclable material at the recycle bin to avoid the sorting later in the process. After sorting the material, the recycle bin compresses the bottles or the cans to accommodate more material into the corresponding material compartment. The invention is a modular arrangement allowing ease of replacing any of the three units of the apparatus: compression, classification, and storage.
US09272839B2 Glass panel packaging box and de-packaging method thereof
Disclosed are a glass panel packaging box and a de-packaging method thereof. The glass panel packaging box includes a box body and a cushioning separator plate arranged in the box body. The cushioning separator plate is arranged between two glass panels. The cushioning separator plate includes a main body corresponding to the glass panels and lugs respectively extending from two opposite side edges of the main body. The box body includes a bottom board and side boards perpendicularly connected to the bottom board. The side boards include receiving slots that correspond to the lugs. The glass panel packaging box and the de-packaging method thereof provide lugs on the cushioning separator plate to make separation of the cushioning separator plate and the glass panel easy so as to increase working efficiency and allow reduction of the thickness of the cushioning separator plate used with a large-sized glass panel.
US09272833B2 Packages for consumable products
Packages (10) for storing, displaying and housing consumable products (18) without loss of product quality and methods of using same are provided. The packages (10) may be shallow enough to promote self-feeding while still allowing for upright display of the package (10). In a general embodiment, the packages (10) of the present disclosure include specific shapes, sizes and/or depths that provide complete coverage of consumable products (18) with sauces, preservatives, juices etc. (20) while still providing functional advantages to a consumer and/or user of such packages (10) who is learning to self-feed. In addition, the consumer product packages (10) having specific shapes, sizes and/or depths also provides for marketing and aesthetic advantages.
US09272826B2 Closure with lock mechanism for fluid products
A closure with a locking mechanism, particularly developed for containers or packaging of fluid products with different consistencies, said closure provided with ergonomic lines which facilitate its handling and further provided with a locking mechanism consisting of a locking pin and a housing to protect the content of the container, safeguarding its properties for a longer period of time, and protecting the user during handling of said dispenser, is provided.
US09272824B2 Flex hinge closure with drain-back channel
A flex hinge closure with a drain-back channel includes a base portion having a dispensing aperture, a raised pour lip formed along a perimeter of the dispensing aperture, a raised rib forming a closed shape surrounding the raised pour lip, and a drain-back channel defined by a space between the raised pour lip and the raised rib. The drain-back channel collects excess material dispensed via the dispensing aperture and drains the excess material back to a receptacle. The closure further includes a cap portion hingedly connected to the base portion. The cap portion rotates relative to the base portion about the hinged connection between a closed position in which the cap portion covers the dispensing aperture and an open position in which the cap portion uncovers the dispensing aperture.
US09272822B2 Dispensing closure assembly for a container
A dispensing closure assembly for a container includes a main body member which is adapted, in use, to be releasably affixable to the container, that main body member including a dispensing outlet and a control member, releasably associated with the main body member, and closure member which is releasably associated with both the main body member and the control member such that movement of the control member allows for selective and controlled movement of the closure member between respective end positions into, and out of, engagement with the dispensing outlet of the main body member.
US09272818B2 Flexible container
A flexible container includes a bottom wall, a plurality of side walls, each extending upwardly from the bottom wall and each having a top end defining an opening into an interior of the container, and a top wall connected to the top end of at least one of the side walls. The top wall covers the opening. A continuous mesh layer is connected to the top end of at least one of the side walls and provides ventilation to the interior of the container. A flexible handle is attached to an exterior surface of at least one of the side walls. The handle includes multiple layers of flexible thermoplastic material connected together, with a first end of the handle being attached to (i) the at least one side wall near the top end thereof, and (ii) the continuous mesh layer.
US09272814B2 Bulk material container
A bulk material container and method for its use is provided. In one or more embodiments, the bulk material container includes: a lid with a lid reinforcement frame positioned substantially at least around the perimeter of said lid, a vertical stop on the exterior of the walls of said container that contacts a projection from an interior wall of said container when one of said bulk material containers is stacked in another, a modular design in which the walls and base of the bulk material container are detachable and replaceable, a stiffening ring positioned around the perimeter of the container walls near their vertical top, and a lid having a lateral motion restraining a system to restrain the lateral motion of one container stacked on another.
US09272813B2 Offshore cargo rack for use in transferring palletized loads between a marine vessel and an offshore platform
A cargo rack for transferring loads between a marine vessel and an offshore marine platform (for example, oil and gas well drilling or production platform) provides a frame having a front, a rear, and upper and lower end portions. The lower end of the frame has a perimeter beam base, a raised floor and a pair of open-ended parallel fork tine tubes or sockets that communicate with the perimeter beam at the front and rear of the frame, preferably being structurally connected (e.g., welded) thereto. Openings in the perimeter beam base align with the forklift tine tubes or sockets. The frame includes a plurality of fixed side walls extending upwardly from the perimeter beam that include at least left and right side walls. A plurality of gates are movably mounted on the frame including a gate at least at the front and at least at the rear of the frame, each gate being movable between open and closed positions, the gates enabling a forklift to place loads on the floor by accessing either the front of the frame or the rear of the frame. Each gate can be pivotally attached to a fixed side wall. The frame has vertically extending positioning beams or lugs that segment the raised floor into a plurality of load-holding positions. Each load holding position has a plurality of positioning beams or lugs that laterally hold a load module (e.g., palletized load) in position once a load is placed on the raised floor.
US09272811B1 Temperature controlled pallet shipper
A thermally insulated pallet shipper is provided for use in any industry where temperature sensitive products are shipped, including the pharmaceutical, hospital and food industries, particularly for shipping payloads by air. The pallet shipper is made from just four individual foam molded structures: a base, a first corner structure, a second corner structure and a lid.
US09272806B2 Storage box
The storage box is formed from a sheet provided with a plurality of folding lines defining a parallelepiped provided with six faces. One of the faces is a hinged lid, and it is characterised in that the opposed face to the hinged lid comprises a first sector provided with an oblique folding line that defines a first joining zone. A second sector also provided with an oblique folding line that is joined to the first sector in the first joining zone; and a third sector is provided with an oblique folding line that defines a second joining zone; and a fourth sector that is joined to the third sector in the second joining zone.
US09272805B2 Systems, methods, and devices for commissioning wireless sensors
In one embodiment the present invention comprises a smartphone and encoders for commissioning RFID transponders. The present invention further includes novel systems, devices, and methods for commissioning RFID transponders with unique object class instance numbers without requiring a realtime connection to a serialization database.
US09272799B2 Sealing tool for strap
A tool for sealing overlying courses of a strap that includes a gripping unit, a power supply unit detachably affixed to one end of the gripping unit, and a motor in the gripping unit. A cam is coupled to the motor and a notching unit is coupled to the cam by a plurality of linkages.
US09272797B2 Tool arrangement with detachable tool locking
The disclosure relates to a tool arrangement, comprising a tool holder, a tool, and at least one locking device for detachably locking the tool with the tool holder, wherein a counter-tool is provided and the tool holder includes a compressed-air duct. The locking device is designed such that it unlocks as soon as a given pressure has been reached in the compressed-air duct. The disclosure is distinguished by a vent hole which is in fluid connection with the compressed-air duct and is arranged in such a manner that it is not closed until the tool rests upon the counter-tool.
US09272796B1 Automatic drug packaging machine and package-less verification system
An automatic drug packaging machine and package-less verification system together with methods and apparatus. In embodiments, the system may include an automatic drug packaging machine for packaging one or more drug into ones of separate pouch packages forming a pouch package web. Each pouch package may include information, a machine-readable code, and have a side through which each packaged drug is viewable. An imager adjacent the web is provided to capture an image of each packaged drug within the pouch package. In embodiments, a code reader adjacent the web may read the pouch package machine-readable code. The code reader may be associated with the imager. In an embodiment, the machine-readable code is compared with an expected code for the pouch package and image information of each packaged drug within the pouch package is compared with a reference image corresponding to each packaged drug for a match. In such embodiment, data may be generated for the pouch package responsive to whether the codes match and whether the images match to provide a verification of the pouch package if the comparisons match and, alternatively, a non-verification of the pouch package if at least one of the comparisons do not match.
US09272783B2 Long endurance aircraft
A long endurance powered aircraft includes a fuselage, a propeller coupled to the fuselage, a wing coupled to the fuselage, and an energy storage system disposed within the fuselage. The wing includes an adjustable surface area including solar cells configured to collect incident solar energy and convert the collected incident solar energy to electrical energy for powering the aircraft during daylight flight. The energy storage system is configured to convert excess electrical energy converted from collected incident solar energy to chemical energy, store the chemical energy, and convert the stored chemical energy to electrical energy for powering the aircraft during night flight.
US09272782B1 Tethering system and method for remote device
A tethering system for a remote-controlled device includes a tether line having a first end adapted to be connected to a ground support and a second end adapted to be connected to the remote-controlled device. The system further includes an anchor-point disposed between the first and second ends of the tether line, the anchor point having an eyelet for securing the tether line and allowing the tether line to slide through the eyelet during use. The anchor-point and eyelet enable the tether line to flex or bend and the remote-controlled device to maneuver one or more of over or around the target area without interfering with any nearby obstructions.
US09272779B2 Aircraft with pivoting rotor mast
An aircraft includes two rotors for rotation about a non-rotating rotor mast. The rotors are driven by permanent and/or electromagnets positioned on each of the rotors. A rotor mast joint connecting the rotor mast to a fuselage or wing of the aircraft permits the rotor mast to tilt relative to the fuselage or wing in at least one plane.
US09272778B2 Device for assisting in piloting hybrid helicopter, hybrid helicopter provided with such device, and method implemented by such device
A hybrid helicopter includes a rotary wing, two half-wings with respective propellers, and an engine installation continuously driving the rotary wing and the propellers by meshing with a mechanical interconnection system. A piloting assistance device for the hybrid helicopter is configured to determine maximum mean pitch (βmax) applicable to the propellers without exceeding the power available for the propellers. The piloting assistance device is configured to determine the maximum mean pitch (βmax) as a function of the current mean pitch of the blades of the propellers as measured in real time, a maximum power that can be delivered by the engine installation, a current power being delivered by the engine installation, and a relationship determining a power gradient (GRD) as a function of pitch for the propellers.
US09272777B2 Helicopter gearbox auxiliary cooling system
A cooling system using one or more heat pipes rotating about a central axis to transfer heat energy from one medium to another. The heat pipes are oriented within a rotating member such that the axis of the heat pipe is non-coaxial with that of a central axis of the rotating member. Centrifugal forces are used to assist the movement of the working fluid within the heat pipe. The cooling system also includes heat pipes associated with a planetary carrier assembly and supplemental heat exchangers for use in aircraft and other machinery.
US09272772B2 Surface element for an aircraft, aircraft and method for improving high-lift generation on a surface element
A surface element, e.g. a wing, of an aircraft includes a leading edge, a high lift device arrangement positioned along the leading edge and at least one add-on body positioned in a leading edge region, wherein the high lift device arrangement is interrupted in the region of at least one add-on body for preventing collision with the add-on body and wherein the surface element includes an arrangement of openings in a region covering the add-on body, which openings are connected to an air conveying device for conveying air through the openings. Thereby an additional flap for harmonizing the flow above a pylon or other add-on body can be eliminated.
US09272771B2 System for anticipating required navigation performance
An onboard flight management system in an aircraft comprises means for continuously calculating first geolocation data, from data received from at least one external geolocation device, comprising a current position and future positions of an aircraft along a trajectory sequenced in several portions and comprising second data comprising demands required by an international navigation procedure called “Required Navigation Performance”, or RNP, for all the portions of the trajectory. The management system additionally comprises a means for displaying first and second data all the way along the trajectory, the first and second data being represented graphically and simultaneously on the said display means in order to enable the pilot to anticipate the flight characteristics for the aircraft and make them converge toward the required demands of the next trajectory portion.
US09272770B2 Method and apparatus for improved lateral control of an aircraft on the ground during takeoff
A method and apparatus for carrying out a symmetric deflection of the spoilers so as to reduce the lift of the aircraft during a takeoff roll thereby improving lateral and directional control on the ground.
US09272769B2 Joint for composite wings
A wing joint including a T-chord and a splice plate for connecting an inboard wing panel assembly and an outboard wing panel assembly. The wing panel assemblies include a stringer co-bonded or co-cured with a wing skin. The webbing and cap of the stringer may be trimmed to expose a noodle and base flange. The noodle and base flange interface with the bottom of the T-chord and the wing skin interfaces with the splice plate. The exposed noodle may be non-flush with the base flange of the trimmed stringer. The bottom of the T-chord may include a groove to accommodate a non-flush noodle so that a gap does not exist between the T-chord and the base flange. Alternatively, shims may be used to compensate for a non-flush noodle or the base flange and web may include sacrificial plies permitting the base flange and web to be trimmed flush with the noodle.
US09272765B2 Rotation and translation control system for vessels
A marine propulsion control system for controlling a set of propulsion units carried by a hull of a vessel is based on the recognition that simultaneous control of yaw and sway movements can be achieved through a control system for a set of propulsion units where two propulsion units achieve yaw movement and two propulsion units achieve a sway movement.
US09272764B2 Remote control device for vessel and remote control method for vessel propulsion device
A remote control device for a vessel is installed in a vessel and remotely controls a vessel propulsion device of the vessel. The remote control device includes an operation member, an operation load applying mechanism, a control section, and an actuator. The operation member is supported rotatably around a rotation axis, and is operated by an operator to switch the shift position of a forward-reverse switching mechanism in the vessel propulsion device according to the operation angle of the operation member. The operation load applying mechanism applies an operation load to the operation member. The control section controls the operation load. The operation load applying mechanism includes an actuator that adjusts the operation load. The control section is arranged to control the actuator based on a vessel speed of the vessel.
US09272763B2 Low water lift assembly
A watercraft lift assembly is provided. The watercraft lift assembly may include a frame, a pair of opposing cantilever arm assemblies and a lifting system. The frame may include a plurality of vertical posts and overhead elements forming a generally simple cubic lattice frame defining a watercraft operational envelope. Each cantilever arm assembly may include a pair of cooperating cantilever arms. Each cantilever arm may be generally L-shaped having a horizontal arm portion and a vertical arm portion slidably secured to an adjacent vertical post. Each horizontal arm portion may include a housing for slidably receiving an extension element. On each cantilever arm assembly, a cantilever bunk may be pivotably connected to the ends of the cooperating extension elements so as to operably engage the bottom surface of various watercrafts when the pair of cantilever arm assemblies moves from a low position to a raised position under the power of the lifting system.
US09272758B2 Method and apparatus for overboarding of a subsea structure
A method for offshore overboarding a structure on a vessel for subsequent lowering the structure to the sea floor, is using a crane (13) to lift the structure at its storage place on a deck of the vessel and move it by means of the crane to a position free of the vessel before lowering it into the sea. During at least a part of the overboarding movement of the structure (1), the structure (1) is forced to follow a track (2) along the deck of the vessel. Two apparatus for performing the method are also presented.
US09272757B2 Evacuation system
The present invention relates to an evacuation system (4) for a vessel (1) or offshore facility, comprising a storage unit (7) having a length, a width and a height defining a volume of the storage unit (7), the storage unit (7) in a storage situation being adapted to house one or more self-propelling, inflatable floatable units (5), the inflatable floatable units each having a capacity of more than 150 persons, and a deployment arrangement (8) having a displacement device, wherein a maximum height of the storage unit is 2.7 meters, and the displacement device is adapted to displace the one or more self-propelling, inflatable floatable units in a substantially horizontal and linear direction out of the storage unit (7) below the maximum height and subsequently lower the one or more self-propelling, inflatable floatable units (5) into the water in a substantially vertical direction.
US09272756B1 Variable buoyancy buoy and deployment methods
A variable buoyancy buoy and method for deployment therefor can include a fixed buoyancy portion formed with a cavity and an enclosure. A pressure hull containing instrumentation can be place in the cavity, and a variable buoyancy portion that can be inserted into the enclosure. The fixed buoyancy portion can have a spar buoy configuration or a marker buoy configuration, and can further be formed with at least one opening to establish a path of fluid communication between the exterior of the buoy and the enclosure. The variable buoyancy portion can be a compressible bladder, or compressible foam, which can change form a maximum volume at the water surface to a minimum volume as the buoy descends towards stowage depth. The decrease in buoyancy facilitates retrieval of the buoy by an apparatus on the ocean floor.
US09272755B2 System for coupling two floating structures
The present invention relates to a coupling system for coupling two floating structures together. The coupling system is able to accommodate the relative rotational and translation motions between the two floating structures without becoming disconnected. Furthermore, the coupling system has an engagement and disengagement mechanism that may be implemented remotely and efficiently.
US09272752B1 Boat with reconfigurable running surface for wake adjustment
A watersports boat includes a hull having an underside defining a running surface that contacts water when the hull moves therein. An aft running surface section of the hull has (a) a trailing edge forming an aft-most point of the contact with water along any given buttock line of the hull when the hull is moving forward, (b) a non-repositionable aft running surface section forming a first portion of the trailing edge, and (c) a re-positionable aft running surface section forming a second portion of the trailing edge. The first portion of the trailing edge and second portion of the trailing edge meet substantially tangent to one another.
US09272750B2 Drive arrangement for a bicycle, having a greater difference in the number of teeth between the largest and the smallest rear chain sprocket
A drive arrangement for a bicycle including a chainring having a chainring axis, a plurality of different rear sprockets, the plurality of rear sprockets sharing a sprocket axis, a drive chain that runs around the rear sprockets and the chainring and in meshing engagement with a selected active sprocket of the plurality of rear sprockets and the chainring, and a rear derailleur. The rear derailleur is configured to shift the chain over a plurality of sprockets having a difference in tooth count of over 25 teeth ranging from a smallest to a largest sprocket.
US09272746B2 Vehicle body frame for a saddle-ride vehicle, and motorcycle including same
A vehicle body frame manufactured by welding is configured for weight reduction, and includes first and second frame members. The first frame member has a predetermined thickness including a first flat surface portion wider than the predetermined thickness. The second frame member includes a second flat surface portion touching the first flat surface portion. The first and second frame members are joined by bringing the flat surface portions together and welding the first and second flat surface portions together with laser beams parallel to the first flat surface portion. In this way, the laser welding can be performed with a reduced gap between the two members. Welding using laser beams applied from directions parallel to the flat surfaces allows the weld area to be significantly larger than conventional fillet welding.
US09272743B2 Spherical modular autonomous robotic traveler
A spherical modular autonomous robotic traveler (SMART) is provided for delivering a payload along a surface from a first position to a second position. The SMART includes an outer spherical shell for rolling along the surface, an inner spherical chamber within the outer shell to carry the payload, a plurality of weight-shifters arranged in the inner chamber, and a controller to activate a select weight-shifter among the plurality. The weight-shifters can be arranged symmetrically or asymmetrically. The outer shell rolls in a direction that corresponds to the activated weight-shifter by torque induced thereby. The inner chamber maintains its orientation relative to the surface, even while the outer shell rolls along the surface. Each weight-shifter includes a channel containing an armature and an electromagnet activated by the controller. For the symmetrical arrangement, the channel is oriented from bottom periphery to lateral radial periphery of the inner chamber. The electromagnet is disposed proximal to the channel at the lateral radial periphery. The armature travels from the bottom periphery within the channel to the lateral radial periphery upon activation of the electromagnet.
US09272739B2 Urban vehicle
A scooter (10) is provided comprising a deck portion (12) mounted on a pair of front wheels (14); at least one tail portion (16) foldably coupled to the deck portion (12) and being narrower than the deck portion (12) and mounted on at least one rear wheel (18) thereby providing the deck portion (12) with stability. The scooter (10) further includes a steering post (20) coupled to the front wheels (14) and being foldable with respect to the deck portion (12).
US09272737B2 Vehicle lower structure
A vehicle lower structure includes: a passenger compartment front wall lower portion separating a vehicle-body front portion and a passenger compartment; and a tunnel portion extending toward a vehicle rear side from a central part of the passenger compartment front wall lower portion in a vehicle width direction and projecting toward a vehicle upper side relative to a vehicle body floor. The tunnel portion includes: a rear tunnel constituent portion, a sectional shape thereof perpendicular to an extending direction of the tunnel portion being a semipolygonal shape; and a front tunnel constituent portion, the front tunnel constituent portion being adjacent to a vehicle front side of the rear tunnel constituent portion, a sectional shape thereof perpendicular to the extending direction of the tunnel portion being a semipolygonal section and the number of corners thereof being larger than the number of corners of the rear tunnel constituent portion.
US09272736B1 Vehicles having a dash panel reinforcement member
Vehicle structures for dissipating and distributing energy associated with a collision are described herein. In one embodiment, a vehicle includes a side support extending in a vehicle longitudinal direction, a rocker support extending in the vehicle longitudinal direction, where the rocker support is positioned outboard of the side support in a vehicle lateral direction, a torque box extending in the vehicle lateral direction, a dash panel coupled to the torque box, where the dash panel comprises an engine room barrier portion extending upward from the torque box and a floor attachment portion extending downward from the torque box, and a reinforcement member positioned between the side support and the rocker support, where the reinforcement member is spaced apart from the side support and the rocker support, and where the reinforcement member is coupled to the engine room barrier portion and the floor attachment portion of the dash panel.
US09272730B2 Electric power steering system
In an electric power steering system, a vehicle reactive force model computes a correction spring reactive torque in such a manner that an elasticity component included in a steering reactive force is increased with an increase in a lateral acceleration. As the lateral acceleration increases, an increase in a basic drive torque is suppressed by a larger amount. By an amount by which the magnitude of the basic drive torque is suppressed, a target pinion angle computed by a target pinion angle computing unit decreases and a correction component for a basic assist component is decreased. A steering assist force is decreased, and a steering reactive force is increased with a decrease in the steering assist force. Thus, it is possible to obtain an appropriate steering reactive force based on the magnitude of the lateral acceleration.
US09272729B2 Steering device for vehicle
Front wheels (6L, 6R) a steering operation of which is possible by a steering mechanism (12) are mounted on a vehicle body (2). Steering cylinders (22L, 22R) of the steering mechanism (12) extend and contract in response to an operation of a steering handle (27) provided in a cab (5) to perform the steering operation of the front wheels (6L, 6R). The steering mechanism (12) is provided with a rotation angle sensor (28) for detecting a steering angle θ of the left front wheel (6L) and a proximity switch (29) for detecting whether or not the front wheel (6L) is in a straight-ahead state. A controller (30) determines that the rotation angle sensor (28) or the proximity switch (29) is abnormal when the steering angle (θ) detected by the rotation angle sensor (28) is different from the detection result by the proximity switch (29).
US09272719B2 Ratcheting railcar indexer
A railcar handling system is disclosed that includes an indexing unit having a plurality of dog carriages, serially aligned in fixed spaced relation, each carriage carrying a railcar axle-engaging dog and a railcar wheel sensor and a hydraulic operating system including a hydraulic cylinder for moving the plurality of dog carriages in unison in a reciprocating ratcheting manner and operating said axle-engaging dogs. A control system is provided to coordinate the operation of the railcar handling system.
US09272713B1 Compliance device, system and method for machine operation
A device, system and method for establishing, determining compliance and ongoing monitoring of a user in the operation of a machine based on predetermined restrictions. The system is useful for a motor vehicle and, more particularly, to comply with user restrictions in teen driving, the presence of passengers, time of day, curfew, range and location, speed, sobriety and the like, An ignition interlock is engaged if one or more sensors that monitor the presence of the vehicle operator, passengers inside the vehicle compartment, and other operational compliance parameters established for the vehicle is out of compliance, and disengaged if compliance is verified.
US09272708B2 Autonomous vehicle entertainment system
A vehicle system includes an autonomous mode controller and an entertainment system controller. The autonomous mode controller controls a vehicle in an autonomous mode. The entertainment system controller presents media content on a first display while the vehicle is operating in the autonomous mode and on a second display when the vehicle is operating in a non-autonomous mode. A method includes determining whether a vehicle is operating in an autonomous mode, presenting media content on a first display while the vehicle is operating in the autonomous mode, and transferring presentation of the media content to a second display when the vehicle is operating in a non-autonomous mode.
US09272707B2 Control apparatus and control method of hybrid electric vehicle
A control apparatus of a hybrid electric vehicle includes: a clutch provided between an engine and a motor generating power; a transmission serially connected to the motor; a driving information detector detecting driving information including an output speed of the motor, an output speed of the transmission, and a rotation speed of a driving shaft serially connected to the transmission; and a controller limiting an input torque of the motor or an input speed of the motor to a predetermined level or less when a difference between the output speed of the motor and the output speed of the transmission detected by the driving information detector is higher than a predetermined value. As a result, it is possible to prevent a hybrid electric vehicle from starting at an unwanted speed.
US09272706B2 Laser ignition system based diagnostics
Methods and systems are provided for enabling engine diagnostics, including visual inspections of an engine cylinder, using existing hardware from a laser ignition system. Light pulses from a laser ignition device are received at a photodetector during non-combusting conditions and used to generate images of an inside of the cylinder that can be assessed by a service technician. An electric motor of the vehicle system can be used during a service mode of the vehicle to rotate the engine to, and hold the engine at, specified engine positions that enable the technician to perform selected diagnostic tests.
US09272703B2 Vehicle drive train control method and system
A vehicle traction system includes a first traction wheel forming part of a first propulsion system including a mechanical drive train, a second traction wheel forming part of a second propulsion system including a hydraulic pump for powering a hydraulic motor, one sensor indicating a take-off condition, and a control unit for controlling the second propulsion unit. The control unit is programmed to automatically detect a take-off condition by the sensor and send an input to the control unit that a take-off condition is fulfilled, automatically provide a traction force from the second propulsion system in response to the indication that there is a take-off condition of the vehicle present and an indication that a traction is or will be provided by the first traction system, and automatically control the second propulsion unit by the control unit in dependence of the manually controlled torque from the first propulsion unit.
US09272702B2 Internal combustion engine control for a hybrid vehicle
When an engine is to be started, operation of the engine is started with injection of fuel from a port fuel injection valve, without injecting fuel from an in-cylinder fuel injection valve (S100). If a gear rattling noise is produced (S110), the engine is operated with fuel injection, from the in-cylinder fuel injection valve, without injecting fuel from the port fuel injection valve (S120). This restrains occurrence of a gear rattling noise.
US09272696B2 Failure diagnosis method for brake system of vehicle
A failure diagnosis method for a brake system of a vehicle determines whether the failure occurs in a regenerative braking device, a front-wheel friction braking device or a rear-wheel friction braking device. The method may include comparing a driver's required acceleration/deceleration with a current acceleration/deceleration of the vehicle, determining that a failure has occurred in the brake system of the vehicle when the driver's required acceleration/deceleration is different from the current acceleration/deceleration of the vehicle and comparing a driver's required braking torque with a regenerative braking maximum torque, and determining that the failure does not occur in the brake system of the vehicle when the driver's required acceleration/deceleration is substantially equal to the current acceleration/deceleration of the vehicle.
US09272694B2 Hydraulic braking system
A hydraulic braking system includes: a cylinder device including a pressurizing piston, a rear chamber, and a front pressure chamber on opposite sides of the pressurizing piston; a brake cylinder coupled to the front pressure chamber; a regulator including a control piston, an input chamber provided at a rear of the control piston, and an output chamber coupled to the rear chamber in front of the control piston; and an input-hydraulic-pressure control device including a high-flow-rate supply unit configured, when an operation of the regulator is started, to supply the working fluid to the input chamber at a set flow rate; and a low-flow-rate supply unit configured, when the supply is finished, to supply the working fluid to the input chamber at a flow rate less than the set flow rate.
US09272693B2 Vehicle brake controller and vehicle brake control method
A vehicle brake controller is capable of executing limit control when a driver is performing a brake pedal operation during turning of a vehicle, to limit an increase in a braking force applied to an inner wheel that is a wheel positioned on the inner side of the turn. The vehicle brake controller is configured to start the limit control when a wheel state value that becomes greater as deceleration of the inner wheel becomes greater exceeds a start determination value that is set to a value greater than zero.
US09272692B2 Method for setting the clamping force exerted by a parking brake
In a method for setting the clamping force, which is exerted by a parking brake, a portion of which clamping force is at least partially generated by an electromechanical braking device having an electric actuator, and another portion is additionally generated by an additional braking device, as needed, the actual force curve is determined and compared to a characteristic, defined force curve to determine the magnitude of the electromechanical clamping force to be supplied by the electric actuator. If the actual force curve corresponds to the characteristic force curve, then, in addition to the electromechanical clamping force, an additional clamping force of the additional braking device is also taken into account for obtaining the setpoint clamping force.
US09272690B2 Parking lock arrangement
Parking lock arrangement, having a parking lock mechanism, which can be moved between a parking lock position and a release position, and having an operating device which is supported so that it can rotate about a first axis and which is designed, through rotation, to operate the parking lock mechanism. The parking lock arrangement further has an actuating mechanism and a coupling device which couples the operating device to the actuating mechanism. The actuating mechanism is supported so that it can rotate about a second axis relative to a drum, which is rotatable about the second axis via a drive.
US09272689B2 System and method for biometric identification in a vehicle
A computer implemented method for identifying a vehicle occupant including receiving a signal from a plurality of sensors, wherein the signal indicates a measurement of cardiac activity, determining a biomarker based on biometric features of the signal and identifying the vehicle occupant based on the biomarker.
US09272684B1 Multi-chamber airbag with pinch valve
An airbag can include a first cushion portion that defines a first inflatable chamber and a second cushion portion that defines a second inflatable chamber. An inflator generates inflation gas to inflate the inflatable chambers. The first inflatable chamber is in fluid communication with the inflator to receive inflation gas to expand the first cushion portion. The second inflatable chamber is in fluid communication with a fill tube or other conduit, which is in fluid communication with the inflator to receive inflation gas to expand the second cushion portion. The fill tube is configured to be disposed between a portion of the first cushion portion and a portion of a vehicle, such that expansion of the first cushion portion as the first inflatable chamber inflates causes the fill tube to be closed. The fill tube is pinched closed against the vehicle portion by expansion of the first cushion portion.
US09272683B2 Dual chambered passenger airbag
An airbag 10 includes at least one panel 12 defining an interior 104/102 of the airbag, and a divider 100 positioned in the interior so as to divide the interior into an upper chamber 102 and a lower chamber 104. A valve mechanism 200 is operatively coupled to the divider 100 for restricting a flow of gases from the lower chamber 104 into the upper chamber 102. The valve mechanism 200 includes one or more valves 200 with a desired aggregate opening(s) and located in predetermined location(s) thereby affecting a designed inflation profile. The divider 100 has an arcuate length Ld, measured between two divider airbag attachment points 100d and 100a, greater than a corresponding linear horizontal airbag length La, measured between the same two attachment points. The passenger side airbag 10 for each unique vehicle is designed by iteratively reconciling the requirements of FMVSS208 with the present airbag design.
US09272679B1 Bumper assembly and side support linking members
Vehicle structures for dissipating energy associated with a collision are described herein. In one embodiment, a vehicle includes a side support extending in a vehicle longitudinal direction, a bumper assembly coupled to the side support and extending in a vehicle lateral direction that is transverse to the vehicle longitudinal direction, and a repositionable joint assembly extending between and pivotally coupled to the side support and the bumper assembly, the repositionable joint assembly including an outboard linking member pivotally coupled to the bumper assembly at a bumper securement location, an inboard linking member pivotally coupled to the side support at a side support securement location, and a fulcrum portion, where the outboard linking member is pivotally coupled to the inboard linking member at the fulcrum portion.
US09272677B2 System and method for providing auxiliary power by regeneration power management in mobile mining equipment
A method for operating an ultracapacitor system used in a mining excavator powered by an power source. The method includes detecting whether a power from the power source is present. Next, a voltage level of the ultracapacitor system is measured if the power is not present. The measured voltage level is then compared with a minimum voltage level for the ultracapacitor system. If the measured voltage level is more than the minimum voltage level, auxiliary power is supplied from the ultracapacitor system to operate mining excavator systems. The auxiliary power may be used to power electronic systems and components such as computers, displays, control systems, gas insulated switchgear and lighting systems.
US09272673B2 System consisting of roof liner and cassette
The present invention relates to a system consisting of a roof liner and a cassette, a method for producing the roof liner, and a method for securing a roof liner to a cassette, in particular a sliding-roof cassette.
US09272672B2 Rear loaded interior badge
A badge mounting system for a vehicle interior includes a badge plate and an emblem or badge comprised of raised lettering or a design that is formed integrally on the badge plate. A trim panel includes inner and outer surfaces and a badge relief section formed integrally on the trim panel. The badge relief section is defined by letter shaped apertures. The badge plate is coupled to the inner surface of the trim panel and the emblem is received in the badge relief section in assembly. The badge plate is rear loaded to the trim panel and the system may include more than one badge plate. In assembly, a portion of the badge extends outwardly from the outer surface of the trim panel through the badge relief section.
US09272670B2 In-vehicle audio apparatus
An in-vehicle audio apparatus includes: a base body that is arranged in a fixed state; a storage tray that is moved between a drawing-out position and a storing position with respect to the base body and inserts and takes out a music reproducing device at the drawing-out position; a pressing body that is moved in accordance with a moving position of the storage tray in a direction perpendicular to a moving direction of the storage tray and presses the music reproducing device that is inserted into the storage tray when the pressing body is moved to one side; and a bias spring that presses the pressing body to the one side.
US09272665B2 Mount assembly
A mount assembly for a vehicle component includes an attachment device configured to attach to a vehicle interior component. The attachment device defines an aperture and includes a vehicle attachment portion, an interior wall, and an exterior wall. A rearview device is configured to operably connect to the exterior wall of the attachment device. An accessory device is configured to operably connect to the interior wall of the attachment device.
US09272664B2 Naked eye 3D video system for backing a vehicle and vehicle including the system
The present invention discloses a naked eye 3D video system for backing a vehicle and vehicles including the system. The naked eye 3D video system includes: two cameras for being installed on the rear of the vehicle and configured to capture images of the scene behind the vehicle respectively; a processor configured to divide the images captured by the two cameras into image strips in equidistance respectively, and integrate alternatively the divided image strips together into a integrated image in the manner of interleave; and a display device for being installed on the instrument panel of the vehicle, and configured to display the integrated image in the form of three dimensions for a driver to watch with the naked eye. The above naked eye 3D video system for backing a vehicle provided by the present invention can make the driver see clearly any obstacle in the scene behind the vehicle and understand spatial distribution information between the vehicle and the obstacle.
US09272657B1 Multi-stage inversion tube mounting system
Methods and apparatus are provided for a mounting system for attaching a container to a vehicle adapted to resist loads imparted by the container to the mounting system in sequential stages. In one exemplary mounting system a first spring is configured to elastically compress when subjected to an initiation load that exceeds a load imparted to the first spring by the container under static conditions. The first spring may have a useable load range from the initiation load to a maximum load at which the first spring is fully bottomed out. A first deformable member is disposed serially with respect to the first spring, and configured to remain substantially un-deformed until subjected to a first deformation threshold load that equals or exceeds the maximum load at which the first spring is fully bottomed out. A second deformable member may be disposed serially with respect to the first deformable member, and configured to remain substantially un-deformed until subjected to a second deformation threshold load that substantially exceeds the first deformation threshold load.
US09272656B2 Apparatus and method for covering a transportable load
An apparatus and method for applying a flexible tarpaulin or other cover to a load which is transportable on a cargo carrier, such as a bed of a trailer truck or the like. The apparatus in preferred forms comprises a block like member which is weighted to counter-act any force imposed on this member. For example, slots in the block like member to receive the forks of the fork lift truck is effective for this purposes. An arm is mounted on and extends outwardly from this block-like member to receive a tube or spindle or spool and which contains a cover wounded thereon. The tube will rotate effectively on the arm as the forklift or other power mover is moved longitudinally with respect to the length of the truck and the cover will unwind from the tube and be draped over the load.
US09272653B2 Grain cart with folding auger
A grain cart and foldable auger assembly having an upper auger assembly portion with a discharge portion, a lower auger assembly portion with an intake portion, and a compound angle joint that allows the upper auger assembly portion to be moved between operating and transport positions. When in an operating position, the upper auger portion and the lower auger portion are offset from each other by an operating offset angle. When in a transport position, the upper auger assembly portion is offset from the lower auger assembly portion by a transport offset angle such that the upper auger assembly portions folded across the front of the grain cart in a non-obstructive and non-protruding manner.
US09272651B1 Storage assembly with cup holder and vehicle including the same
In one or more embodiments, a storage assembly with a cup holder includes a housing including a track extending in a longitudinal direction and a first cavity partially defining the cup holder, a cover including a foot portion and movable along the longitudinal direction between first and second open positions via engagement of the foot portion and the track, and one or more retractable protrusions supported on the cover and providing access for facilitating movement of the cover relative to the track.
US09272646B2 Plastic foamed article
Provided is a plastic foamed article to be attached to an attaching target having a rod-shaped attaching portion having a radial direction, the plastic foamed article including a holding portion for holding the attaching portion in the radial direction in a state attached to the attaching target, the holding portion including a pair of opposite surfaces facing each other for holding the attaching portion between the pair of opposite surfaces and a protrusion provided on one of the pair of opposite surfaces, and at least a part of the protrusion is configured to be elastically deformed by the attaching portion in a state in which the attaching portion is held between the pair of opposite surfaces.
US09272640B2 Modular transit system
A modular seat assembly having an elongate support spine extending longitudinally from a first end to a second end is provided. A seat portion is connected to a front side of the support spine, and each of the seat portion and the support spine includes one of a complementary pair of interlocking portions. The interlocking portion of the seat portion slides onto the interlocking portion of the support spine over the first end. The modular seat assembly further includes an end cap lockably disposed over the first end that prevents the seat portion from sliding off the support spine.
US09272631B2 Method and charging station for traction battery of an electric vehicle with automatic, motorized positioning of station-side coupler to inductively charge through the vehicle license plate
A charging station for charging a vehicle includes a charger, a camera, a positioner, and a controller. The charger has a transformer part by which electrical energy can be transferred to a corresponding transformer part arranged behind the vehicle license plate when the charger is in a position relative to the license plate at which the transformer parts sandwich the license plate. The camera generates positional information indicative of positioning between the charger and the license plate. The positioner can move the charger within a range of motion. When the license plate is within the range of motion, the positioner moves the charger based on the positional information to the position at which the transformer parts sandwich the license plate. The controller uses the positional information to generate instructions indicative on how to drive the vehicle to a position in which the license plate is within the range of motion.
US09272629B2 Power system switching between charge-discharge function and driving function and electric vehicle comprising the same
A power system switching between a charge-discharge function and a driving function and an electric vehicle including the same are provided. The power system includes a power battery; a charge-discharge socket; a bidirectional DC/DC module; a driving control switch connected with the power battery and the bidirectional DC/DC module; a bidirectional DC/AC module connected with the driving control switch and the power battery; a motor control switch connected with the bidirectional DC/AC module and a motor; a charge-discharge control module connected with the bidirectional DC/AC module and the charge-discharge socket; and a controller module configured to establish a path between the power battery and the motor when a current operation mode of the power system is a driving mode, and to establish a path between the charge-discharge socket and the power battery when the current operation mode of the power system is a charge-discharge mode.
US09272627B2 Energy storage systems and methods
In an energy storage system that includes a battery and an ultracapacitor, the state of charge (SOC) of the capacitor is the subject of a dynamic set-point. This dynamic set-point control is a function of the load regime to which the storage system is exposed, for example a hybrid automobile or electric automobile. The control may be based in part upon real-time fast Fourier transform analysis of load current, permitting real-time adjustment of control coefficients. In this way, it is possible to minimize the occurrence of the capacitor being fully charged at a time when it would be desired to be able to absorb high current, for example from regenerative braking. Likewise it is possible to minimize the occurrence of the capacitor being nearly discharged at a time when it would be desirable to have boost power available. A result is that even a relatively small ultracapacitor (having perhaps one two-hundredth the energy storage capacity of the battery) can permit greatly reducing waste heat dissipated in the battery, and can reduce otherwise unnecessary cycling of current into and out of the battery. This can extend battery life and battery performance.
US09272626B2 Devices and methods for the safe driving, charging and energy recovery operation of an electric vehicle
The invention relates to a method and an electrical protection and monitoring device with an insulation monitoring instrument and a differential current monitoring instrument in an electric vehicle for safe driving operation and also for safe charging and energy recovery operation of the electric vehicle at a charging station. The invention further relates to a device for the safe charging and energy recovery operation of an electric vehicle at a charging station with electrical protection and monitoring devices.
US09272625B2 Power supply system for powering an electric load of a vehicle
An electrical power supply system for powering an electric load of a vehicle includes a main battery, a support battery and a battery control module. The battery control module includes a first terminal for connection to the main battery, a second terminal for connection to the support battery and a third terminal for connecting to the electric load. A switch is arranged between said second terminal and said third terminal. The battery control module is arranged to connect the support battery to the load by turning the switch conducting in case the voltage at the third terminal drops below a predetermined voltage. The system provides the automatic activation of a support energy source when the output voltage falls below a specified voltage threshold. The support battery supports the main battery when needed or acts as a redundant power source.
US09272623B2 Display device
Provided is a display device with which it is possible to implement a novel display. A display device comprises: a display unit which displays a display image in a display region; a framing unit is configured from a plurality of components; and a moving device which moves at least one of the plurality of components. The framing unit is segmented by moving at least one of the components by the moving mechanism. Prior to segmenting, the framing unit surrounds a partial region of the display region of the display unit. The display unit displays a different display image before and after the segmenting of the framing unit, and displays a notification image which fits the shape of the framing unit at least either before or after the segmentation of the framing unit.
US09272618B2 Misfuelling prevention device for a filler neck of a fuel tank
A misfuelling prevention device for a filler neck of a fuel tank includes a tubular element with an inflow side and an outflow side and a closure element, which, when in an open state, permits a flow of fuel through the outflow side, and, when in a closed state, prevents a flow of fuel through the outflow side. In a shell surface of the tubular element there is formed at least one opening which permits a flow of fuel from an inner side of the tubular element through to an outer side of the tubular element. The tubular element can be mounted such that at least a part of the shell surface in which the at least one opening is formed is arranged spaced apart from an inner surface of the filler neck such that fuel flowing through the at least one opening can flow via the filler neck into the fuel tank.
US09272617B2 Anti-misfueling filler neck device
An anti-misfueling filler neck device includes sliding projections mounted at the bottom of a housing to move laterally to allow a flapper to be opened only when a fuel gun for a diesel vehicle is inserted, thus preventing gasoline from being injected into the diesel vehicle.
US09272614B1 Variable or stepped louver activation for active grille system
An active grille system which is mounted to a fascia, grille, or carrier, or is part of the carrier of an automobile. Two sets of louvers are rotatably mounted to a frame, and a camming mechanism provides selective actuation of both sets of louvers, and an actuator controls the camming mechanism such that the actuator moves the camming mechanism between a first position, a second position, and a third position. When the camming mechanism is in the first position, both the first set and second set of louvers are in a closed position, when the camming mechanism is in the second position, the first set of louvers are in an open position and the second set of louvers are in a closed position, and when the camming mechanism is in the third position both the first set and second set of louvers are in an open position.
US09272613B2 Straddle type vehicle
An inner cowl and a radiator upper cowl surround a radiator cover. An air guide is provided inside a radiator. A first air duct sends traveling air flow to the radiator while a second air duct, spaced laterally inwardly from the radiator, bypasses the radiator and sends cool traveling air flowing toward a driver's legs via a slit provided in a rear radiator cover.
US09272611B2 Sealing strand for adhesively bonding to a vehicle body
A sealing strand for adhesively bonding to a vehicle body, in particular to a body flange protruding from a vehicle body, uses a device for attaching the sealing strand to the vehicle body, in particular to the body flange, prior to the adhesive bonding. In particular, the device for attaching the sealing strand in a starting position is used for the adhesive bonding with the aid of an application device which exerts contact pressure.
US09272609B2 Method for closing a convertible soft top
A method for operating a convertible top of a motor vehicle. The convertible top may be a soft top which may be opened and closed in an electric or hydraulic manner using, in a non-limiting embodiment, a mobile device after the mobile device receives data relating to the monitoring of an interior space and an exterior region of the motor vehicle.
US09272601B2 Vehicle air conditioner case
Provided is a vehicle air conditioner which includes a simple water-proofing structure that is capable of preventing flooding of a vehicle cabin from mating surfaces, etc. of expansion-valve covers and top and bottom divided cases of an air conditioning unit (HVAC unit) without employing a water-proofing cover, or the like. In a vehicle air conditioner in which expansion-valve covers (6 and 7) that are horizontally divided into two parts are provided at an outer surface side of top and bottom divided cases of an air conditioning unit disposed in the vehicle cabin so as to bridge mating surfaces of the cases; an expansion valve can be disposed inside the expansion-valve covers (6 and 7); and, in addition, the interior of the expansion-valve covers (6 and 7) communicates with an engine compartment via an opening provided in a toe board, step portions (11) in which inner surface sides (9) are made lower and outer surface sides (10) are made higher are formed at the top and bottom mating surfaces of the expansion-valve covers (6 and 7).
US09272591B2 Gooseneck trailer with coupling link actuators
Trailer with a detachable gooseneck having a deck supported toward the rear by ground engaging wheels, mating surfaces on the gooseneck and the deck which abut against each other when the gooseneck is attached to the deck, coupling pins extending along spaced apart, parallel axes from the gooseneck and the deck on opposite sides of the abutting surfaces, a coupling link movable along the pin on the gooseneck between a first position in which the link engages the pin on the deck and a second position in which the link is disengaged from the pin on the deck, and an actuator for moving the coupling link between the first and second positions. A latch hook is rotatively mounted on the deck to the rear of the abutting surfaces for engagement with a laterally extending latch bar which depends from the gooseneck, and a pneumatic actuator is operatively connected to the latch hook for moving the latch hook into and out of engagement with the latch bar.
US09272590B2 Trailer tongue alignment apparatus
An alignment assembly that automatically aligns the inverted ball socket on a trailer tongue and temporarily raises the ball socket over a ball mounted on the end of the towing vehicle as the towing vehicle is being backed up. The assembly includes a tongue mount attached to the front edge of the ball socket on a trailer. The tongue mount includes a vertical, transversely aligned front plate in front of the ball socket. Selectively attached to the front plate is a vertical sliding transverse plate that attaches to a forward extending, diagonally aligned guide tunnel. The guide tunnel includes a wide front opening and narrow rear opening that terminates directly in front of the ball socket. During use, the ball travels rearward into the guide funnel which creates a lifting force on the guide funnel. Upward force on the guide funnel causes the trailer tongue to lift. When the ball clears the guide tunnel, the ball socket falls and is aligned with the ball.
US09272582B2 Pneumatic tire
A pneumatic tire has bead cores provided in bead portions. The bead cores include a first bead wire, and a second bead wire having an elongation α, where α(%)=ΔL/L×100, L is a length of each of the bead wires under no load, and ΔL is an elongation amount obtained when a unit load is applied. The elongation α of the second bead wire is greater than an elongation of the first bead wire. The number of the second bead wire provided in an innermost side portion in a tire radial direction is at least one.
US09272581B2 Pneumatic tire
A pneumatic tire is provided in the outer surface of each sidewall portion with a serrated zone formed by a number of serration grooves extending at an angle of at most 45 degrees with respect to the tire radial direction. Each of the serration grooves has a variable depth such that the deepest point lies between the radially outermost end and innermost end of the serration groove. The deepest point is positioned in a range between 0.2 time and 0.4 times a radial distance Ha from the maximum carcass section width position to the radially outermost end of the tire. As a result, the rolling resistance of the tire can be reduced.
US09272580B2 Pneumatic vehicle tyre for utility vehicles
The invention relates to a pneumatic vehicle tire for utility vehicles having a belt which has a plurality of belt layers and having a tread (1) with circumferential grooves (6, 7, 8) which run in the circumferential direction and divide the tread (1) into circumferential ribs (2). An envelope h which runs parallel to the periphery of the tread in the tread (1) and is in contact with the deepest circumferential groove or grooves from the radially inner side, defines, together with the periphery of the tread and the shoulder-side edge sections (5), a tread gross volume (V), wherein all the grooves (6,7,8) in the tread (1) define a groove volume (VR) between 5% and 28% of the tread gross volume (V), wherein three circumferential grooves (6,7,8) are provided which are arranged over the axial width of the tread (1) in such a way that the first circumferential groove (6) is arranged in the region of the one edge (10) of the widest belt layer, the second circumferential groove (7) is arranged in the region of the other edge (11) of the widest belt layer of the belt, and the third circumferential groove (8) is arranged between the first circumferential groove (6) and the second circumferential groove (7) in the tread (1), and wherein the first and second circumferential grooves (6, 7) each have a groove volume (VR1,2) between 1.25% and 7.00% of the tread gross volume (V), and the third circumferential groove (8) has a groove volume (VR3) of the first or of the second circumferential groove which is at least twice as large.
US09272576B2 Structurally supported, non-pneumatic wheel with continuous loop reinforcement assembly
A non-pneumatic wheel is provided having a continuous loop reinforcement assembly that can support a load and have performance similar to pneumatic tires. Various configurations of a non-pneumatic wheel, including variations of the continuous loop reinforcement assembly, are provided. One or more resilient spacers can be positioned with the continuous loop reinforcement assembly and can be configured for the receipt of a matrix material.
US09272567B2 Method and apparatus for transferring images onto a curved surface
The application of image transfer paper and a wrap to a curved surface of a container is described. A device for affixing the image transfer paper and wrap includes a base, a support member to support the container, and two wrap applicator arms coupled to the base in a pivoting manner. The support member includes a shoulder and, when the container is placed upon the support member, an edge of the container around an opening of the container rests upon the shoulder and a perimeter of the shoulder extends beyond a perimeter of the edge of the container. The shoulder receives the image transfer paper and aligns the image transfer paper with the edge of the container. Each wrap applicator arm is configured to receive a respective end of the wrap. Rotating the wrap applicator arms about the support member stretches the wrap around the container and image transfer paper.
US09272566B2 Support structure for hanging file folders
A support structure has a pair of elongate side panels and a pair of end support frame assemblies for maintaining the side panels in a mutually spaced relationship and at an elevation to enable suspension of hanging file folders from the side panels. Each of the side panels includes a top member, a bottom member spaced apart from the top member, and at least one reinforcing member interconnecting the top and bottom members. Each of the top and bottom members has opposite terminal ends each formed as a connecting member having a vertical slot. Each of the end support frame assemblies includes a pair of support legs configured to extend through the vertical slots of the respective connecting members of the side panels and includes at least one transverse support member having opposite terminal ends configured to be releasably mounted to respective ones of the support legs.
US09272563B2 Sliding panel box gift card holder
A gift card holder includes a two-leaf sliding panel mounted within a box that frames an image or object. In a first position, the panel covers the image or object within the box. In a second position, when the panel is partially drawn upward, the interior of the box is revealed. In a third position, when the panel is drawn completely upward, the two leaves of the panel open to reveal a gift card secured between the leaves.
US09272562B2 Book forming and pressing machine
A book forming and pressing machine includes a pressing device that has a number of spaced-apart pressing plates, joint-burn-in rails and at least one station for accommodating a book block. A loading device has a loading table. A reshaping device includes a mechanism to shape a front cut of a book block. The mechanism includes a tool carrier having a shaping tool to shape the front cut. Tool carrier and/or the shaping tool executes a series of movements in one plane or in three-dimensional space, relative to the front cut to be shaped, while the book block is held in the pressing device.
US09272559B2 Color erasing apparatus
In accordance with one embodiment, a color erasing apparatus capable of erasing the color of an image formed with a color erasable material on a sheet comprises a color erasing section configured to erase the color of an image formed on the sheet; a control panel configured to set a reading area of the sheet; and a reading section configured to read the image of the area set on the sheet and determine the state of the image erased by the color erasing section.
US09272549B2 Recording apparatus
A recording apparatus includes a medium support section that has a supply section supplying a continuous-shaped recording medium, a medium path through which the recording medium supplied on the supply section passes, and a transportation mechanism that transports the recording medium; and a recording section that performs recording on the recording medium passing through the medium path. A hole that is formed in a side wall having a light shielding property and capable of visually recognizing the inside of the medium path on the upstream side from the transportation mechanism in a transportation direction through the inside of the medium support section is provided in the medium support section.
US09272545B2 Recording apparatus
In a recording apparatus, a first path and a module path of a first recording module for conveying and recording of a recording medium are formed such that a distance between the most downstream ejection opening and a joining position of the first path and a second path is less than a length of a recording medium. The controller executes: a first determination processing for determining whether there is a recording medium which should be conveyed through a join determination position before the recording medium having been supplied to the first recording module; and a wait processing for causing the recording medium having been supplied to the first recording module to wait in a state in which its leading edge is located upstream of the most upstream shared conveyor on the first path, when the controller determines that there is a recording medium.
US09272543B2 Printing device, tray and conveyance device
A printing device that prints on media held in a tray includes a first roller section including a first conveyance roller; a second roller section including a second conveyance roller and a pinch roller; and a printing section provided between the first and the second roller sections. Printing is performed on the top surface of the media in the printing section while the tray is being conveyed by the first and the second roller sections. The tray is such that friction surfaces having a coefficient of friction that is higher than that of the other portions of the tray are formed in portions that come in contact with the first conveyance roller when the tray is taken in by the first roller section and the tip end of the tray advances to a gripping section between the second conveyance roller and the pinch roller.
US09272535B2 Printer
This is disclosed a printer comprising a feeder, a printing head, a take-up body, and a print control portion. The feeder feeds a recording medium. The printing head forms desired print in a predetermined print area of the recording medium fed by the feeder. The take-up body sequentially takes up the recording medium on an outer circumference part with a tip end region of the recording medium positioned on downstream side in a transport direction than the print area connected to the outer circumference part and produces a roll-shaped printed matter. The print control portion controls the printing head so as to form a print part for preheating the printing head in a position that serves as a border between the tip end region and the print area of the recording medium.
US09272533B2 Image processing method and image processing apparatus
To provide an image processing method, including: image recording, wherein an image composed of a plurality of laser drawn lines is recorded by heating by irradiating parallel laser lights on a recording medium spaced by a predetermined distance, wherein, in the image recording, among the plurality of laser drawn lines constituting the image, at least two units of lines drawn with different energy, each composed of a pair of laser drawn lines adjacent to each other and with different irradiation energy, are formed.
US09272530B2 Droplet discharging method and droplet discharging apparatus
A droplet discharging method includes: forming a plurality of dots on a first region of a medium, on a second region which is positioned in a −Y direction from the first region, and on a third region which is positioned in the −Y direction from the second region. The dots are formed on the first region by using a first head, the dots are formed on the second region by using the first head and a second head so that a second head use ratio is increased from a value less than a first set value to a value greater than a second set value greater than the first set value in the −Y direction, and the dots are formed on the third region by using the first head and the second head to cause the second head use ratio to be constant.
US09272508B2 Element substrate, printhead, and printing apparatus
An element substrate capable of suppressing occurrence of electromagnetic noise upon driving printing elements on an element substrate with long wiring lengths, preventing an operation error, and printing a high-quality image is provided. In the element substrate, plural element substrates each including printing elements are arrayed in an arrayed direction of the printing elements. Each element substrate including a wiring for supplying a driving power to drive the printing elements, and a ground wiring from the printing elements is configured as follows. Each element substrate includes a delay circuit for delaying a heat enable signal to drive the printing elements and supplying it to each printing element, and a switchover circuit for switching over, in accordance with a control signal, a delay sequence when supplying the heat enable signal to each printing element.
US09272507B2 Liquid ejecting head and liquid ejecting apparatus
A liquid ejecting head includes a flow channel forming substrate having pressure generation chambers communicating with a nozzle opening and arranged in parallel along a lateral direction. A piezoelectric element is provided on one surface of the flow channel forming substrate in correspondence to the pressure generation chamber, and has a first electrode, a piezoelectric layer provided on the first electrode and a second electrode provided on the piezoelectric layer. In a direction intersecting with the arrangement direction of the pressure generation chambers, in boundaries between an active section that is a substantial driving section and an inactive section that is not a substantial driving section of the piezoelectric layer, the first electrode includes a taper section of which a width is gradually decreased toward the boundary from the active section side.
US09272506B2 Systems and methods for implementing an advanced inker unit surface conditioning system in a variable data digital lithographic printing device
A system and method are provided for providing an improved inker unit surface cleaning and conditioning system, including in a single anilox chamber blade system, for improving image quality, including eliminating ghosting, in a proposed variable data digital lithographic image forming architecture. Techniques are provided to remove acquired oil from an inking member. A particularly-configured containment encloses a cleaner (disturber) roller to emulsify the acquired oil on the inking roller. The cleaner roller is preferably configured with a pliable surface including a silicon roller surface over a porous base. The silicon roller (1) absorbs dampening solution oil; and (2) agitates ink that may be still held in certain cells/cavities of the inking member or roller. In embodiments, a vacuum pressure is applied to the inside of the hollow cleaner roller to better remove the residual ink and dampening solution from the inking roller.
US09272505B2 Printing apparatus with pad
A printing apparatus is described. The printing apparatus has at least one pad including a cavity and a printing surface, a printing device adapted to form at least one image portion on the printing surface of the least one pad, a pad moving apparatus adapted to orient the pad in a first working position in which the image portion is formed in the printing surface of the pad by means of the printing device and in a second working position, different from the first working position, in which the image portion is imprinted on the object to be decorated by pressing the pad onto the object, a further device adapted to act on the cavity of the pad to determine a flat shape of the printing surface of the entire pad in the first working position and a substantially convex shape of the printing surface of the entire pad in the second working position.
US09272504B2 Flexographic printing unit with knee lever system and narrow web label printing press having at least one flexographic printing unit
A flexographic printing unit includes an engraved roll, a form cylinder and an impression cylinder. Axes of rotation of the engraved roll and the form cylinder are disposed in a horizontal plane and axes of rotation of the form cylinder and the impression cylinder are disposed in a vertical plane. The printing unit has at least one knee lever system for applying a pretensioning force to the form cylinder. A narrow web label printing press having at least one flexographic printing unit is also provided.
US09272503B2 Seal for doctor blade devices and doctor blade device having a seal
A seal for a doctor blade device in a printing press includes a blade contacting section with a front side engaged with a doctor blade of the doctor blade device and a rear side that is softer, more elastic or more resilient than the front side. A doctor blade device having a seal is also provided.
US09272502B2 Cartridge and tubular container trimming and refinishing apparatus for ink and label removal and method of use
A device for removing a thin outer layer from the surface of a cartridge or tubular container such as a caulk cartridge for removal of ink, contaminant, adhesive, or printed or stamped label from the outside of the cartridge. The apparatus includes cartridge hopper and a cartridge handling mandrel or plunger which automatically removes a cartridge from the hopper aligning same for insertion of the cartridge axially through the throat of a spinning ring which contains at least one and preferably a plurality of inwardly extending knifes. The spinning knife distal end trims or peels off the label, adhesive, ink, imperfections, or even a thin film from an outer layer of a selected thickness effectively reconditioning the cartridge for reuse to be filled with virgin material or to be used as uncontaminated re-ground material to be sold as scrap.
US09272500B2 Cushioning elements for apparel and other products and methods of manufacturing the cushioning elements
A method for manufacturing the cushioning elements may include utilizing a die with a plurality of die elements positioned in a particular arrangement. A polymer material, which may be a polymer foam material, is located between the die and an extractor. The polymer material is compressed between the die and the extractor, and the die elements cut the polymer material to form a plurality of pad components, which are arranged like the die elements. The die and the extractor are separated, and the pad components are secured to the extractor in the arrangement of the die elements. Additionally, the pad components are bonded to at least one material layer such that the pad components remain in the arrangement of the die elements.
US09272487B2 Method for producing a decorative leather element
The present application relates to a method for producing a composite body comprising a flexible decorative material for use as decorative trim having a visible surface in a motor vehicle. The method comprises first joining a plurality of material pieces to form a material block, and then severing one or more composite bodies from the material block. The severing is carried out such that the severed composite body contains several of the material pieces. Thereafter, the severed composite body is applied to a visible surface of a decorative trim.
US09272486B2 Stitched multi-layer fabric
A stitched fabric including an interior layer, a barrier layer disposed over the interior layer, the barrier layer configured to inhibit fluid flow, a batting layer disposed over the barrier layer, the batting layer configured to provide insulation, a yarn stitched through and securing together the interior layer, the barrier layer, and the batting layer, the yarn forming stitch holes in the barrier layer, and a face layer disposed over the barrier layer, a melted portion of the barrier layer bonding the face layer and the barrier layer together and filling a portion of the stitch holes in the barrier layer.
US09272483B2 Methods, systems and products involving sheet products
A method for forming a tubular sheet product roll includes providing a sheet product roll having a first configuration and a void, centering a rotational axis of the sheet product roll on a longitudinal axis of a first tool, and inserting the first tool into the void of the sheet product roll to define an inner diameter of the void and to form the sheet product roll having a second configuration different from the first configuration.
US09272482B2 Petal shaped greeting card and method
A foldable greeting card and method of making the card, with a polygonal base with hinged lobes attached to the edges of the base, with the lobes foldable inward to the center of the base. The lobes overlap neighboring lobes. The card is made by affixing at least two separate units to each other, so that each hinged lobe overlaps by a neighboring lobe and is overlapped by a neighboring lobe. A message or graphic may be placed on the lobes or the base.
US09272474B2 3D mold for manufacturing of sub-micron 3D structures using 2-D photon lithography and nanoimprinting and process thereof
A process to manufacture a 3D mold to fabricate a high-throughput and low cost sub-micron 3D structure product is disclosed. The process integrates use of 2-photon laser lithography and 3D write technology to make a 3D mold of each layer of the 3D structure product, and then use nanoimprinting to form a sheet of polymer film of each layer of the 3D structure from the said 3D mold of that layer. Each layer of the sheet of polymer film is then fabricated into the sub-micron 3D structure product. The 3D mold of each layer of a high-throughput and low cost sub-micron 3D structure product, is further used to make master molds which is then used to form a sheet of polymer film of each layer of the 3D structure to fabricate the sub-micron 3D structure product. Applications using this process are also disclosed.
US09272473B2 Wettable silicone hydrogel contact lenses and related compositions and methods
Silicone hydrogel contact lenses having ophthalmically acceptable surface wettabilities are obtained from pre-extracted polymerized silicone hydrogel contact lens products having relatively large amounts of removable or extractable materials. The silicone hydrogel contact lenses can be obtained from non-polar resin based contact lens molds and without surface treatments or an interpenetrating polymeric network of a polymeric wetting agent. Related lens products, polymerizable compositions, and methods are also described.
US09272472B2 Method of shaping an optical element that is elastically deformed by an adhesively-bonded ring
A method of shaping an aspherical optical element is provided that includes the steps of fastening an optical element blank to a ring, the blank presenting an optical surface that is to be shaped and a surface referred to as a rear surface; applying forces and moments to the ring in order to deform the optical element and its optical surface, which element is fastened to the ring; using abrasion to shape said deformed optical surface so as to restore a spherical or planar shape thereto; and extracting the blank from the ring so as to release the stresses deforming said shaped optical surface so as to allow it to acquire the desired aspherical shape. The method also includes the step of fastening the blank to the ring is performed by bonding the optical surface or the rear surface to a surface of the ring with a layer of adhesive.
US09272470B2 Method of fabricating an aircraft part by infusing resin
The method of fabricating an aircraft part comprises the steps of placing in a stack comprising a preform at least one layer of a material that presents permeability to a predetermined resin that is less than the permeability of a portion of the preform that is the closest to the layer; and placing a resin presence sensor on a side of the layer that is remote from the preform.
US09272467B2 Method for producing a decorative part, and such a decorative part
A method is provided for producing a decorative part that has a closed cross-section having an external visible side and that has at least two support parts to be connected along a connecting joint. The support parts are held spaced at a distance from one another such that a gap is formed between the edges of the support parts which adjoin one another at the connecting joint. The support parts are inserted in at least two halves of a molding tool. A reaction plastic is injected into the molding tool, such that the reaction plastic penetrates the gap. The support parts are moved toward each other such that the gap closes while the reaction plastic is still liquid. The support parts are fixed against each other in this position at least until the plastic has sufficiently cured so as to form a bond seam in the connecting joint.
US09272465B2 High-quality flame-retardant decorative finish for interior panels
A high-quality, fire-resistant, decorative finish for panels made of composite material, such as aircraft interior panels. Starting with a flat or complex contoured panel, a flame-retardant filler primer is applied to the panel surface. This filler primer is then sanded to a very smooth solid surface. In a separate process, a polymeric film is printed with a desired pattern or image. The polymeric film is then bonded to the primed panel surface using an adhesive. The non-printed side of the polymeric film is bonded to the panel. A thin highly durable polymeric coating (clear or tinted) is then applied to the exposed printed side.
US09272461B2 Bag
A thermoplastic bag may include a sidewall that may have a plurality of first and second ribs formed therein. The first ribs may be longer in length but shorter in height than the second ribs. The second ribs may be arranged in discrete networks that appear superimposed over the first ribs. The second ribs may normally remain in a bent-over configuration. When a force is applied, the second ribs may expand the area of the sidewall so that the bag may easily accommodate large objects. To produce the bag, a thermoplastic web may be directed between opposing first and second rollers. One of the rollers may include ridges that may have first and second segments of differing heights that correspond to the differing heights of the first and second ribs. The formation of the first ribs may increase the width of the web.
US09272459B2 Bag
A thermoplastic bag may include a sidewall that may have a plurality of first and second ribs formed therein. The first ribs may be longer in length but shorter in height than the second ribs. The second ribs may be arranged in discrete networks that appear superimposed over the first ribs. The second ribs may normally remain in a bent-over configuration. When a force is applied, the second ribs may expand the area of the sidewall so that the bag may easily accommodate large objects. To produce the bag, a thermoplastic web may be directed between opposing first and second rollers. One of the rollers may include ridges that may have first and second segments of differing heights that correspond to the differing heights of the first and second ribs. The formation of the first ribs may increase the width of the web.
US09272458B2 One-piece blow mold halves for molding a container
A blow mold is disclosed. The mold comprises a pair of mold halves having an operative configuration wherein said mold halves together define a cavity for a container. The container has a main body and a characteristic selected from the group of characteristics consisting of: a push-up base; an integral finish; and an embossed or a debossed feature. Each of the pair of mold halves has a first portion and a second portion formed integrally with the first portion. When the pair of mold halves is in the operative configuration, the first portions collectively define the main body and the second portions collectively define the characteristic. The blow mold can be used for prototyping, and can also be used for production.
US09272456B2 Injection stretch blow molding process
The present invention relates to a process for blow molding a polyethylene container comprising the steps of: a) providing a solid preform made from a polyethylene material having a melt flow index from 0.01 to 10.0 g/10 minutes, wherein the preform comprises a neck region, side walls and a base region, and wherein the side walls between the neck region and the base region have substantially straight and parallel outer walls; b) reheating the preform so that the maximum temperature difference between the hottest and coldest regions of the side walls and the base region of the reheated preform is less than 4° C.; c) transferring the reheated preform to a blow mold; d) stretching the preform at a pressure below 10 bars; and e) increasing the pressure within the reheated preform so as to cause the walls of the stretched preform to expand to the shape and dimensions inside the blow mold. A polyethylene container made according to the present invention preferably has a minimum wall thickness of the container of less than 200 micrometers, and a weight to volume ratio of the empty container of less than 50 grams per liter.
US09272454B2 Side gate nozzle assembly
Disclosed is a side gate nozzle assembly (108) having a nozzle body (210) and at least one side gate nozzle tip assembly (112) wherein the nozzle body (210) and the at least one side gate nozzle tip assembly (112) are slidably engaged to each other.
US09272451B2 Body for a passenger car
A method for producing a body of a passenger car is provided. A plurality of body components are connected to each other, the body components are provided at least in part with a plastic. The body is produced in a combined internal high pressure forming and injection molding process.
US09272449B2 Method for making lens array
An exemplary method for making a lens array requires an imprinting mold and a substrate. A blob of molding material is applied on each molding section of the substrate. First alignment marks, and second alignment mark of the imprinting mold aligned with third and fourth alignment marks on each one of the imprinting regions, respectively. The imprinting mold is pressed on the molding material on the imprinting region. The pressed portions of the imprinting region are solidified to obtain lenses in the imprinting region. The imprinting mold is pressed on another one of the imprinting region, and the imprinting mold is removed. This process is repeated for each other imprinting region. Thus, a large-scale lens array is obtained.
US09272448B2 Cellulose resin film, process for producing cellulose resin film, antireflection film, polarizing plate, and liquid crystal display
A cellulosic resin film which is wide and, despite this, is extremely reduced in breakage during a stretching step; a process for producing the film; and an antireflection film, a polarizer, and a liquid-crystal display each comprising or employing the film. The process for cellulosic resin film production comprises casting a liquid cellulosic resin on a support to form a web, peeling the web from the support, subsequently drying the web in a first edge gripping step (105) while gripping both edges, temporarily eliminating the edge gripping, and then stretching both edges in the width direction in a second edge gripping step (109). The process is characterized in that the first edge gripping step is followed by a heat treatment step in which both edge parts of the web relieved from the edge gripping are heated with heating rolls (107 and 108).
US09272447B2 Powder application device and method for producing thermoplastic moldable semi-plastic finished goods
There is proposed a powder application device P for producing blanks of thermoplastically deformable semifinished products for use as reinforcement elements, starting from a powder mixture containing a meltable plastics powder, comprising a downwardly open powder container B and a perforated stencil L, arranged beneath the latter and spaced apart therefrom, having one or more hole cutouts, said device being characterized in that the powder container B is rigidly connected to the perforated stencil L and is vertically lowerable as far as an auxiliary support or a distance of at most 5 mm therefrom, and is closable at its lower end by means of a horizontal closing plate S having a thickness slightly less than the distance between the powder container B and the perforated stencil L, wherein the closing plate S is movable in a horizontal plane such that it alternately closes and reopens the lower end of the powder container B.
US09272446B2 Process for melting/sintering powder particles for the layer-by-layer production of three-dimensional objects
A process for melting/sintering powder particles for layer-by-layer production of three-dimensional objects wherein a layer of powder particles is irradiated by a nonlinear path of an electromagnetic radiation is provided. Also provided are an apparatus to conduct the process and three dimensional objects obtained by the process.
US09272443B2 Ceramic-powder and/or metal-powder press tool, ceramic-powder and/or metal-powder press, modular system with such a press tool, method for assembling and operating a ceramic-powder and/or metal-powder press tool or a press
The invention relates, in particular, to a ceramic-powder and/or metal-powder press tool, comprising at least one base body (21), a plurality of at least two punches (22-25) which, in a press position, are arranged to be insertable from one side into a die cavity (3) of a die (2) filled with ceramic and/or metal powder (P), a plurality of at least two punch carriers (26-29) each for the attachment of one of the punches, wherein at least part of the die carriers (28; 29) is couplable to at least two adjustment drives (39-42) and wherein the punch carriers are arranged to be adjustable relative to each other and relative to the base body, and positive-stop devices (48°, 49, 50) arranged to divert at least part of a pressing force (Fp) from the punches via the base body in a press end position, wherein at least one of the punch carriers is coupled to or mounted on at least two coupling rods (30-33) and each of the coupling rods is couplable to or mountable on its own such adjustment drive. Electromotive adjustment drives are particularly preferred.
US09272441B2 Method of sealing a porous fibrous substrate, and method of making a door
A method of surface sealing a porous fibrous substrate is provided. According to the method, a porous fibrous substrate possessing a moisture content and a surface with pores is provided. A sealant composition is applied to a surface of the porous fibrous substrate and permitted to penetrate the surface pores of the porous fibrous substrate and undergo cure while participating in a foaming reaction with the moisture content to establish a water-resistant polymeric foam sealant impregnated into the porous fibrous substrate. The water-resistant polymeric foam sealant contains a polyurethane and/or polyurea.
US09272438B2 Guide bar having a carbon fiber reinforced plastic insert
A guide bar for a chain saw has an elongate main body of steel. The main body has flat sides and upper and lower peripheries defining a guide groove for a saw chain. An elongate window is formed in the main body between the peripheries and is filled with an insert made of a fiber composite material made up of resin and fibers. The fibers are in the direction of the longitudinal axis of the main body. The insert includes a plurality of fiber layers that are bonded with resin. A central layer is formed from a fiber layer and the fibers thereof are at an angle to the longitudinal axis. Two fiber layers having fibers oriented in the direction of the longitudinal axis of the main body are on both sides of the central layer. The inner fiber layers are covered outwardly by a woven fabric.
US09272437B2 Fluid distribution components of high-pressure fluid jet systems
High-pressure fluid jet systems are provided which include a pump to selectively provide a source of high-pressure fluid, a cutting head assembly configured to receive the high-pressure fluid and generate a high-pressure fluid jet for processing workpieces or work surfaces, and a fluid distribution system in fluid communication with the pump and the cutting head assembly to route the high-pressure fluid from the pump to the cutting head assembly. The pump, the cutting head assembly and/or the fluid distribution system include at least one fluid distribution component having a unitary body formed from an additive manufacturing or casting process with an internal passage having at least a curvilinear portion to efficiently route matter through the fluid jet system. Example fluid distribution components include fittings, valve bodies, cutting head bodies and nozzles of the high-pressure fluid jet systems.
US09272434B2 Cutting apparatus, holding member, and cutting member
A cutting apparatus including a plurality of types of holding members holding a workpiece and a plurality of types of cutting members cutting the workpiece held by the holding member. Each holding member includes a sheet of base, a holding portion disposed on a surface of the base and having a holding capacity suitable for a type of the workpiece to be held, and a holding member indicator capable of distinguishing the types of holding members. Each cutting member includes a cutter having a blade configured to cut the workpiece and having a cutting capacity suitable for a type of the workpiece to be cut, a support portion supporting the cutter, and a cutter indicator provided on the plurality of types of cutting members and capable of distinguishing the types of cutting members, the cutter indicator being similar in configuration as the holding member indicator of corresponding holding member.
US09272432B1 Apparatus and method for clamping and cutting compressible materials
An apparatus for cutting expanded fibrous and soft foam materials has a linear clamping feature with an integrated blade guide, suspended in a position to allow unobstructed travel of a cutting blade. Compression and cutting features are separated so that the cutting blade is protected from undue wear, cuts are consistent and uniform, and the apparatus is safe to use.
US09272431B2 Polarizing sheet removing tool and removing method
A method is provided for removing a polarizing sheet with a tool that includes a handle including a main body forming therein a channel for receiving adhesive dissolving liquid, a piston device mounted inside the channel, and a guide tube mounted on the main body, and a blade mounted to the handle. The guide tube has an end in communication with the channel and an opposite end positioned on the blade to guide the adhesive dissolving liquid from the channel to the blade. The polarizing sheet is removed by lifting up a portion of the polarizing sheet and placing the blade against bonding adhesive between the polarizing sheet and a substrate to which the polarizing sheet is attached to allow the adhesive dissolving liquid to be guided by the guide tube toward the blade for subsequently flowing toward and dissolving bonding adhesive.
US09272422B2 Grasping method by grasping apparatus
A grasping method is by a grasping apparatus that is provided with a grasping portion that has a plurality of pawl portions, and a plurality of contact portions that are provided on portions of the plurality of pawl portions, which contact a workpiece, and that are able to be hardened. The grasping method includes conforming the contact portions to an outer shape of a master workpiece that has an outer shape that is able to deform the contact portions to a shape for positioning the workpiece; hardening the contact portions in a state conformed to the outer shape of the master workpiece; positioning the workpiece; and grasping the positioned workpiece with the grasping portion by hardening the contact portions while keeping the contact portions in the shape conformed to the outer shape of the workpiece.
US09272419B2 Robotic picking line for serialized products
Various embodiments are directed to a system for managing an inventory comprising serialized products. A computer system may receive from an intake sensor a first tray identifier describing a first tray present on an intake transport system. The computer system may also associate the first tray identifier with a first serial identifier of a first product unit present on a product transport system and instructing the product transport system, by the computer system, to transport the first product unit to the first tray. Additionally, the computer system may instruct a robot to place the first tray containing the first product unit at a first bin selected from a plurality of robot-accessible bins.
US09272415B2 Robot device
A robot device includes a robot and a controller. The robot includes a base, an arm body, and a plurality of actuators. The arm body comprises a multi joint structure composed of a plurality of arm elements. The plurality of actuators is configured to drive the plurality of arm elements. The controller is configured to control operations of the plurality of actuators. Each of the plurality of arm elements includes a frame member and an elastic outer skin. The frame member is configured to constitute a support structure at least for gravity. The elastic outer skin is constituted by an elastic body and arranged so as to form a surface outer skin of the arm element while covering the frame member.
US09272414B2 Robot arm assembly
A robot arm assembly includes a first robot arm, a second robot arm, a third robot arm, a connecting base, a first driving assembly, a second driving assembly, a third driving assembly, and a cable receiving tube. The connecting base includes a housing and a protection cover. A sidewall of the housing defines an opening. The protection cover covers the opening and is mounted on the housing. An end of the housing defines a cable inlet. The first driving assembly rotates the first robot arm. The second driving assembly rotates the second robot arm. The third driving assembly rotates the third robot arm. The cable receiving tube is received in the first robot arm, the second robot arm, and the third robot arm.
US09272412B2 Workpiece transfer device
A workpiece transfer device includes a base, a rotating portion rotatably mounted on the base, and a transfer mechanism mounted on the rotating portion. The transfer mechanism includes a rotational housing, at least one bearing table, and a driving device. The bearing table is received in the rotational housing. The bearing table is configured to support a workpiece. The driving device is operable to drive the bearing table to slide in the rotational housing.
US09272411B1 Mechanic's creeper
A creeper (10) includes a longitudinally extending pad (11) having a body portion (12), a headrest (13) at one end of the body portion (12) and an extension (14) at the other end of the body portion (12). A frame (15) carries the pad (11) and includes longitudinally extending laterally spaced side rails (16, 17) positioned at the lateral periphery of the pad body portion (12), and laterally extending longitudinally spaced cross rails (18, 19) positioned at the longitudinal periphery of the pad body portion (52). Support rails (21, 22) are carried by the cross rails (18, 19) and are positioned at the periphery of the headrest (13) and at the periphery of the pad extension (14), respectively. Caster assemblies (25) are located outside of the profile of the pad (11), and a cover (30) is positioned over each caster assembly (25). The caster assemblies (25) are attached to the cover (30) with an extension (34) of the side rails (16, 17) positioned therebetween.
US09272405B2 Staple refill, stapler, and cartridge
A staple refill includes a refill body accommodating sheet-type connected staples. The refill body includes a bottom wall, a right wall provided on a right side of the bottom wall, and a left wall provided on a left side of the bottom wall. A pressing member is provided in the refill body in a movable manner to press the sheet-type connected staples. The refill body is formed with an opening such that the sheet-type connected staples inside the refill body are visible through the opening, and the pressing member includes a protruding portion configured to enter the opening.
US09272400B2 Torque-limited impact tool
Illustrative embodiments of torque-limited impact tools are disclosed. An impact tool may include a shaft adapted to rotate about an axis, a hammer having a hammer jaw with an obtuse impact surface, and an anvil having an anvil jaw with an acute impact surface. The shaft may include a first helical groove, and the hammer may include a second helical groove. The impact tool may further include a ball received in the first and second helical grooves, wherein the ball rotationally couples the hammer to the shaft and permits axial travel of the hammer relative to the shaft. The obtuse impact surface of the hammer jaw may be adapted to impact the acute impact surface of the anvil jaw when the shaft rotates in a first direction.
US09272396B2 Water softener filter wrench system
In general, the invention is a wrench made of a heavy and rust-resistant steel, which is 7-gauge in a preferred embodiment, as well as zinc coated in a primary embodiment, formed to one of the water filter sizes, including but not limited to: SW1, SW2, SW3, SW5-a, 144880 BW-BC, C-shaped (open end) Universal style, S3072, HT-HTF, OW1, OW2, OW6. The handle is at least 1.5 times the head diameter for easy use and the head is fitted with the various water filter sizes. A plastic or rubber cover is used on the handle for grip and for installing directions.
US09272395B2 Multiple-in-one socket
A multiple-in-one socket includes a socket body having a first gradational cavity recessed in a first end of the socket body, and a second gradational cavity recessed in a second end of the socket body opposite to the first gradational cavity; each gradational cavity including a plurality of polygonal holes gradationally contracted in sizes inwardly from an outermost hole towards an innermost hole; whereby a plurality of polygonal holes having plurality of hole sizes may be conveniently chosen for fastening a bolt or nut by correspondingly matching the bolt (or nut) size with the polygonal-hole size.
US09272389B2 Polishing apparatus and polishing method
A polishing apparatus capable of monitoring an accurate progress of polishing is disclosed. The polishing apparatus includes: a polishing table for supporting a polishing pad; a table motor configured to rotate the polishing table; a top ring configured to press a substrate against the polishing pad to polish the substrate; a dresser configured to dress the polishing pad while oscillating on the polishing pad during polishing of the substrate; a filtering device configured to remove a vibration component, having a frequency corresponding to an oscillation period of the dresser, from an output current signal of the table motor; and a polishing monitoring device configured to monitor a progress of polishing of the substrate based on the output current signal from which the vibration component has been removed.
US09272377B2 Production system and article producing method
An assembling device (a production system) includes robots that produce a piping component from a plurality of types of parts, and a display that accepts an input of lot information of at least one of the plurality of parts used in producing operations by the first to third robots and that outputs unsuitable condition information when an unsuitable condition in any of the parts is detected, the unsuitable condition information identifying a lot of the any of the parts in which the unsuitable condition is detected.
US09272376B2 Fatigue-resistant nickel-titanium alloys and medical devices using same
Superelastic and/or shape memory nickel-titanium alloys having an increased fatigue life that is superior to known nickel-titanium alloys are disclosed. The nickel-titanium alloys have a minimum fatigue life that may be at least about 10 million strain cycles at a strain greater than about 0.75%. The minimum fatigue life may be due, at least in part, to the nickel-titanium alloy having at least one of an oxygen concentration of less than about 200 ppm, a carbon concentration of less than about 200 ppm, the absence of oxide-based and/or carbide-based inclusions having a size greater than about 5 microns (μm), the presence of an R-phase, or combinations of the foregoing. Articles manufactured from such fatigue-resistant nickel-titanium alloys can be more durable because they are more resistant to repetitive strain and crack propagation.
US09272374B2 Golf club head with grooves and method of manufacture
Embodiments of golf clubs with grooves and methods of manufacture thereof are described herein. Other embodiments and related methods are also disclosed herein.
US09272373B2 Device for assembling brackets in an aircraft structure
A positioning device for assembling parts on a structure is disclosed. More specifically, the positioning device is designed for assembling fixed brackets to an aircraft structure. A laser projector is fastened directly on the rigid aircraft structure; its position is therefore stable in relation to the latter, even if the structure undergoes slight deformations. The position of the projector is determined accurately by utilizing targets, which are also fastened to the primary structure. A method for implementing the positioning device is also disclosed.
US09272370B2 Laser ablating structures for antenna modules for dual interface smartcards
Laser etching antenna structures (AS) for RFID antenna modules (AM). Combining laser etching and chemical etching. Limiting the thickness of the contact pads (CP) to less than the skin depth (18 m) of the conductive material (copper) used for the contact pads (CP). Multiple antenna structures (AS1, AS2) in an antenna module (AM). Incorporating LEDs into the antenna module (AM) or smartcard (SC).
US09272365B2 Superalloy laser cladding with surface topology energy transfer compensation
A superalloy substrate, such as a turbine blade or vane, is fabricated or repaired by laser beam welding to clad one or more layers on the substrate. Laser optical energy is transferred to the welding filler material and underlying substrate to assure filler melting and adequate substrate surface wetting for good fusion. Energy transfer is maintained below a level that jeopardizes substrate thermal degradation. Optical energy transfer to the filler and substrate is maintained uniformly as the laser beam and substrate are moved relative to each other along a translation path by varying the energy transfer rate to compensate for localized substrate topology variations.
US09272363B2 Hybrid laser plus submerged arc or electroslag cladding of superalloys
A method for cladding of superalloy materials. A layer of powder (14) disposed over a superalloy substrate (12) is heated with an energy beam (16) to form a layer of superalloy cladding (10) and an overlying layer of slag (18). A filler material (44) of nickel, nickel-chromium or nickel-chromium-cobalt wire or strip is also added to the melt pool to combine with the melted powder via a submerged arc or electroslag heating process to give the superalloy cladding the composition of a desired superalloy material. The layer of powder includes a layer of powdered flux material (22) over a layer of powdered metal (20), or the flux and metal powders may be mixed together (36).
US09272362B2 Friction stir weld plugs and methods of using thereof
In one aspect of the disclosure, an article for filling an opening in an object includes a plug having a body, a first flange, and a second flange. The plug has a trailing end. The first flange is in contact with the body and extends away from the body. The second flange is in contact with the first flange and extends away from the first flange and the body. The second flange is configured to deform toward the body upon installation of the plug into the opening. This deformation of the second flange rotationally and translationally secures the plug in the opening and consolidates the plug in the opening.
US09272361B2 Method for joining metal materials
A method for joining metal materials, which joins a first member with at least a joining face made of Metal A, the Metal A being mainly composed of at least one selected from the group consisting of Al, Cu, Ag and Au, to a second member with at least a joining face made of Metal B, the Metal B being mainly composed of at least one selected from the group consisting of Al Cu, Ag and Au, includes interposing an insert between the joining faces of the first and second members, wherein the insert contains Zn as a metal capable of causing an eutectic reaction with at least one metal except for Au in Metal A as well as at least one metal except for Au in Metal B.
US09272356B2 Feed control method for consumable electrode AC arc welding
A feed control method is provided for consumable electrode AC arc welding, in which the welding wire is fed at a predetermined wire feed rate, and a welding voltage applied to an arc is switched in alternation between positive polarity and negative polarity. In the method, a welding current setting signal is generated. The wire is fed at a first feed rate during a period of the positive polarity, whereas the wire is fed at a second feed rate different from the first feed rate during a period of the negative polarity.
US09272354B2 Cylinder device
The present invention relates to the provision of a cylinder apparatus that is able to maintain a superior join condition, and has: a cylindrical cylinder (11); an end portion member (12) that is placed on the end portion side of the cylinder (11); and a weld portion (13) that fixes an outer circumferential side of the cylinder (11), when this has been engaged with an inner circumferential side of the end portion member (12), to one end of the end portion member (12) by means of a weld, wherein abutting portions (21), which abut in the circumferential direction against a contact portion (60) of the end portion member (12) and notch portions (20) are provided alternatingly in the circumferential direction on the end portion side of the cylinder (11), and the notch portions (20) form communicating passages (69) that connect the weld portion (13) to an inner circumferential side space (67) inside the cylinder (11) or end portion member (12).
US09272350B2 Method for resistance braze repair
Metallic components, including superalloy components such as turbine vanes and blades, are joined or repaired by electric resistance with a high electrical resistivity brazing alloy composition. In some embodiments the brazing alloy comprises filler metal selected from the group consisting of nickel, iron, and cobalt base alloy and elements selected from the group consisting of phosphorous (P), boron (B), silicon (Si), germanium (Ge), sulfur (S), selenium (Se), carbon (C), tellurium (Te) and manganese (Mn). In performing the method of the present invention a high electrical resistivity brazing alloy composition is introduced within a substrate defect or interposed between two substrates that are to be joined. An electric current is passed through the brazing alloy until the alloy melts and bonds to the adjoining substrate. High resistivity of the brazing alloy concentrates heat generated by the current flow in the brazing alloy rather than in the substrate.
US09272349B2 Numerical control device, wire electric discharge machining apparatus using the same, and wire electric discharge machining method using the same
A numerical control device for a wire electric discharge machining apparatus generates a wire-breakage sign signal, outputs a machining-condition re-setting instruction and wire-breakage threshold re-setting instruction from the wire-breakage sign signal and wire-breakage threshold, sets the wire-breakage threshold according to the wire-breakage threshold re-setting instruction and a wire-breakage signal, calculates a machining energy from a discharge pulse count, measures a machining speed from position information, calculates a board thickness of the workpiece from the machining energy and machining speed, outputs, according to a predetermined algorithm, a machining-condition switching instruction from the board thickness, the machining-condition re-setting instruction, and the wire-breakage signal, sends an oscillation instruction to a oscillator and sends a shaft feed instruction to a servo amplifier so that the machining condition is set to one determined by the machining-condition switching instruction, and stores the machining condition and wire-breakage threshold that correspond to each board thickness.
US09272346B2 Portable foam panel cutting machine
A foam panel cutting machine for cutting foam panels used in insulated building panels. The foam panel cutting machine has a feeder system feeds the foam panel through the cutting blades. The cutting machine additionally includes a frame, a plurality of upper rollers and a plurality of lower rollers rotationally mounted to the frame. The foam panel cutting machine can be constructed so that it may be portable. One embodiment includes the upper rollers on an adjustable head that can adjust the gap distance between the upper and lower rollers so that foam panels of various thicknesses may be cut. The cutting blade may be a hot-knife wherein the blade is heated by passing an electrical current through it. The cutting blade may have a “L” or “J” shape to cut kerfs into the foam panel that receive metal studs to form an insulated building panel.
US09272337B2 System and method for forming a bore in a workpiece
A method of forming a bore through a workpiece with a drill by monitoring drill orientation and bore position; and adjusting drill path as necessary. Adjusted the drill path includes selectively applying an axial impulse to the drill when the drill is in a designated azimuthal orientation. Drill orientation and bore position are monitored with an acoustic transmitter and receiver disposed adjacent an outer surface of the workpiece. The acoustic transmitter and receiver are moved at the same rate at which the drill axially progress through the workpiece, so that they are aligned with the bottom of the bore.
US09272336B2 Cutting insert, cutting tool, and method of manufacturing machined product using them
A cutting insert according to an embodiment of the present invention includes an upper surface, a side surface, and a first cutting edge located at an intersection of the upper surface and the side surface. The upper surface includes a pair of raised parts located opposite to each other with a perpendicular bisector of the first cutting edge interposed therebetween. A top of each of the pair of raised parts includes at least two protrusions oriented toward a direction along the perpendicular bisector in a top view. Each of the at least two protrusions includes a first protrusion located on a side closest to the perpendicular bisector, and a second protrusion which is located on a side further away from the perpendicular bisector than the first protrusion, and is located at a higher position than the first protrusion. A cutting tool including the cutting insert, and a method of manufacturing a machined product by using the cutting tool are also provided.
US09272332B2 Near net shape manufacturing of rare earth permanent magnets
A method of near net shaping a rare earth permanent magnet and a permanent magnet. The method includes introducing a magnetic material powder into a die, closing the die and shock compacting the powder in the die and sintering the compacted magnet powder to form the rare earth permanent magnet part. In one form, the magnetic material being subjected to compaction is a mixture made up of two or more different magnetic material powder precursors. Additional materials may be added to the mixture. One such additional material may be a lubricant to reduce the likelihood of cracking, while another may be a coating to provide oxidation protection of the mixture. Evacuation or inert environments may also be used either prior to or in conjunction with the sintering or related high-temperature part of the process.
US09272325B2 Environment servo type clean metal casting mold
An environment servo type clean metal casting mold has a casting mold body with an ingate. The casting mold body includes a cold bottom mold plate and a peripheral mold plate that is connected with the cold bottom plate. The peripheral mold plate is provided with a vertical temperature break servo device. The temperature of the vertical temperature abrupt servo device contacting with the cooling metal varies in the vertical direction, hence the liquid metal has rapid heat emission, crystallization and solidification.
US09272323B2 Method for imparting improved fatigue strength to wire made of shape memory alloys, and medical devices made from such wire
Wire products, such as round and flat wire, strands, cables, and tubing, are made from a shape memory material in which inherent defects within the material are isolated from the bulk material phase of the material within one or more stabilized material phases, such that the wire product demonstrates improved fatigue resistance. In one application, a method of mechanical conditioning in accordance with the present disclosure isolates inherent defects in nickel-titanium or NiTi materials in fields of a secondary material phase that are resistant to crack initiation and/or propagation, such as a martensite phase, while the remainder of the surrounding defect-free material remains in a primary or parent material phase, such as an austenite phase, whereby the overall superelastic nature of the material is preserved.
US09272321B2 Guided keeper and method for metal forming dies
A guided keeper assembly includes a base, at least one marginal fastener aperture to detachably mount the base to an associated die shoe, and a central guide aperture. A guide pin is closely received in the central aperture of the base. A first end of the guide pin has an enlarged head to positively limit travel between the die shoe and die pad, and an opposite second end with a generally flat terminal shoulder configured for close reception in a blind hole in the die pad. The shoulder has a fastener aperture at a location spaced radially offset from the central axis of the guide pin. A fastener extends through the fastener aperture in the die pad and engages in the fastener aperture in the second end of the guide pin to securely, yet detachably, connect the second end portion of the guide pin with the die pad.
US09272320B2 Cemented carbide punch
The present invention relates to a punch for manufacturing of metal beverage cans of a cemented carbide comprising a hard phase comprising WC and a binder phase the cemented carbide composition comprises, in wt-%, from 50 to less than 70 WC, from 15 to 30 TiC, and from 12 to 20 Co+Ni.
US09272319B2 Machining tool for machining sheet metal
A machining tool, such as a forming, embossing, punching or pinching tool carries at least two tool elements at radial external faces for processing sheet metal. The tool elements are fixed to a tool body, either as separate pieces or integrated therein, and the tool body is rotatably supported in a receptacle. The tool body is rotatable about a rotation axis which is not perpendicular to the sheet metal during processing.
US09272318B2 Method for producing a hollow profiled section
The object of setting out a method, with which substantially crack and/or fold-free greatly curved hollow profiles can be produced, is achieved by a method for producing a hollow profile having a curved portion which has a center of curvature, wherein a blank is preshaped to form a U-shaped profile by introducing a punch into a first die and the U-shaped profile is shaped with a second die to form an O-shaped profile having at least one longitudinal slot, the blank being preshaped to form a U-shaped profile whose outer limb which faces away from the center of curvature and which is associated with the curved portion is at least partially higher than the inner limb thereof which faces the center of curvature and which is associated with the curved portion.
US09272315B2 Mechanisms for controlling gas flow in enclosure
Embodiments of mechanisms for controlling a gas flow in an interface module are provided. A method for controlling a gas flow in an enclosure includes providing the enclosure which is capable of containing a substrate. The method also includes providing a gas into the enclosure. The method further includes cleaning the gas. In addition, the method includes actuating the gas to generate the gas flow, and the gas flow passes through the substrate when the substrate is located in the enclosure.
US09272314B2 Dishwasher steam purge method
A steam purge method for a dishwasher includes a washing cycle, a steam purge cycle and a rinse cycle. During the steam purge cycle, a dishwasher tub is filled with fluid to a level below a heating element in a wash chamber, heated and at least partially converted to steam in the wash chamber. After the steam purge cycle, the dishwasher is drained and the rinse cycle commences. Optionally, a heated drying cycle may be performed upon termination of the rinse cycle. A single heating element arranged in the wash chamber is utilized for heating washing fluid during each of washing, purging and steam generation cycles, as well as for the heated drying cycle.
US09272312B1 Methods and systems for removing lubricants from superplastic-forming or hot-forming dies
A method of cleaning a superplastic-forming or a hot-forming die includes exposing a surface of the die having a lubricant thereon to electromagnetic energy. The electromagnetic energy removes the lubricant without removing an oxide layer between the die surface and the lubricant.
US09272301B2 Apparatus and method for non-contact manipulation, conditioning, shaping and drying of surfaces
Non-contact method and apparatus for Drying, Conditioning, Shaping and Manipulating of sheet fed Media. These functions are performed either on one side, or simultaneously or delayed one from the other on both sides, of the Media. For Drying, the energy applied is minimized to that necessary to supply latent heat of vaporization permitting use in, for example, low cost printers. No friction is introduced in the transport path enabling high speed, reliable Media transport. A region is established between Media and Platen wherein heat, support, and chemical or other processing may occur in a controlled way. Relatively few, inexpensive, and small parts are needed lowering the cost, energy, and space requirements for performing the various functions allowing for new applications in many fields. Media is supported a specific distance from a Platen by a balance of Fluid forces. The Media and the Platen bound a region in which forced convection greatly enhances process rates otherwise be limited by diffusion. The method and apparatus described is particularly suitable for high speed, low cost, inkjet printing.
US09272296B1 Gas powered fluid gun with recoil mitigation
A gas powered fluid gun for propelling a stream or slug of a fluid at high velocity toward a target. Recoil mitigation is provided that reduces or eliminates the associated recoil forces, with minimal or no backwash. By launching a quantity of water in the opposite direction, net momentum forces are reduced or eliminated. Examples of recoil mitigation devices include a cone for making a conical fluid sheet, a device forming multiple impinging streams of fluid, a cavitating venturi, one or more spinning vanes, or an annular tangential entry/exit.
US09272295B2 Sprayer assembly
The present invention provides a sprayer that has on the sprayer itself capability for simultaneously controlling on/off function and flow selection. A forward button can be pressed by a forefinger to turn flow on, while a rearward rocker can be controlled by a thumb to select between aerated and non-aerated flow. The on/off control is biased to the off position.
US09272282B2 Combined thermal devices for thermal cycling
The invention relates to systems and methods including a combination of thermal generating device technologies to achieve more efficiency and accuracy in PCR temperature cycling of nucleic samples undergoing amplification.
US09272280B2 Device, systems and methods for evaluation of hemostasis
Provided are devices, systems and methods for evaluation of hemostasis. Also provided are sound focusing assemblies.
US09272275B2 Method and system for the selective oxidative decarboxylation of fatty acids
Selective, radically initiated oxidative decarboxylation may produce low viscosity renewable fuels from biologically derived fats and oils. Fatty acids and triglycerides may be decarboxylated using oxidants at a water/oil interface. The oxidants may be produced using photo-Fenton reagents. The reaction advantageously can be carried out at room temperature and pressure and has fewer unwanted byproducts than traditional decarboxylation techniques.
US09272271B2 Manufacture of catalyst compositions and systems
A method of producing a catalyst composition is provided, the method comprising mixing (i) a first component comprising a zeolite, and (ii) a second component comprising a homogeneous solid mixture containing at least one catalytic metal and at least one metal inorganic support, wherein the first component and the second component form an intimate mixture, and wherein the homogeneous solid mixture is produced by mixing a reactive solution comprising a precursor of the metal inorganic support and a templating agent with a precursor of the catalyst metal, and calcining the mixture to form the homogeneous solid mixture. The templating agent affects one or more of pore size, pore distribution, pore spacing, or pore dispersity of the metal inorganic support. The pores of the solid mixture produced after calcination may have an average diameter in a range of about 1 nanometer to about 15 nanometers.
US09272269B2 Catalytic hollow fibers
A hollow fiber for use in production of hydrogen gas. The hollow fiber contains a porous support layer having an outer surface and an inner surface, a catalyst layer coated on the outer surface, and a selection layer coated on the inner surface. Also disclosed is a method of preparing such a hollow fiber.
US09272268B2 Catalysts for low temperature oxidation
The invention provides a composite catalyst containing a first component and a second component. The first component contains nanosized gold particles. The second component contains nanosized platinum group metals. The composite catalyst is useful for catalyzing the oxidation of carbon monoxide, hydrocarbons, oxides of nitrogen, and other pollutants at low temperatures.
US09272265B2 Method for suppressing increase in SO2 oxidation rate of NOx removal catalyst
In a NOx removal catalyst used for removing nitrogen oxides in flue gas, when a silica (Si) component as an inhibitor that causes an increase in a SO2 oxidation rate accumulates on a surface of the catalyst, the silica component accumulating on the surface of the catalyst is dissolved, thereby regenerating the catalyst. Accordingly, the inhibitor such as the silica component covering the surface of the NOx removal catalyst can be removed, thereby enabling to provide a catalyst without having an increase in the SO2 oxidation rate of the regenerated NOx removal catalyst.
US09272261B2 Organic-inorganic hybrid chiral sorbent and process for the preparation thereof
The present invention provides an organic-inorganic hybrid chiral sorbent for chiral resolution of various racemic compounds viz. racemic mandelic acid, 2-phenyl propionic acid, diethyl tartrate, 2,2′-dihydroxy-1,1′-binaphthalene (BINOL) and cyano chromene oxide with excellent chiral separation (enantiomeric excess, 99%) in case of mandelic acid under medium pressure column chromatography. These optically pure enantiomers find applications as intermediates in pharmaceutical industries.
US09272257B2 Removal of atmospheric pollutants from gas, related apparatus, processes and uses thereof
Methods related generally to the removal of atmospheric pollutants from the gas phase, are provided, as well as related apparatus, processes and uses thereof. A single-stage air scrubbing apparatus is provided that includes at least one reaction vessel, at least one introduction duct, and a turbulence component, wherein a residence time is sufficient to allow the conversion of at least one atmospheric pollution compound to at least one other compound, molecule or atom. In some embodiments, the at least one atmospheric pollution compound comprises nitrogen oxide, sulfur oxide or a combination thereof. Additionally, methods of removing atmospheric pollution compounds from a waste gas stream are disclosed that include introducing a waste gas stream and at least one additional gas stream, mist stream, liquid stream or combination thereof into a single-stage air scrubbing apparatus at a flow rate sufficient to allow for conversion of the at least one atmospheric pollution compound.
US09272254B2 Efficient in-situ catalyst sulfiding methods and systems
A system and method is disclosed for efficiently sulfiding metal catalyst resident in a reactor vessel comprises a sulfiding module and a hydrogen sulfide detection module and a remote computer all arranged and configured to communicate wirelessly and to allow remote control and monitoring of the modules and sulfiding process.
US09272253B2 Mobile tank container provided with a valve gear for allowing circulation of a liquid
A mobile tank container arranged to transport a liquid, comprising a circumferential wall which extends around an axis in a driving direction of the mobile tank container and two end walls which close the container volume at the front side and the rear side, wherein the tank container is provided with a valve gear comprising at least one valve which extends into the container volume, such that the valve, when used while the tank container is at least substantially full with liquid, comparatively allows circulation of liquid in the container volume in one tangential circulation direction around the axis or in one axial circulation direction along the axis, or a combination of the two directions, in the open position thereof, and that the valve comparatively impedes circulation of liquid in the opposite circulation direction in the closed position thereof.
US09272251B2 Method and apparatus for maintaining microcarrier beads in suspension
The invention relates to an impeller for use in a bioreactor for growing adherent mammalian cells and/or a cell separator for adherent mammalian cells. The impeller of the invention is designed to efficiently and rapidly lift a bed of settled cells and microcarrier beads at low rotational speeds. Cell growth and concomitant yield is therefore improved by maintaining the culture in an environment of low shear force.
US09272250B2 Automated mix in-cup apparatus and the method of operating the same
The present disclosure describes an automated blend in-cup apparatus and the related method of operation. The disclosure relates generally to the field of mixing consumable material. More specifically, the disclosure relates to a mixer that is automatically operable to lower a mixing blade into a cup or vessel that contains material to be blended/mixed. A shield is automatically lowered to at least partially isolate the cup. The apparatus further comprises a well with an inlet manifold and a drain and a fixed but removable cup-receiving holder. The shield can include a magnetic portion that is detected by a first sensor on the apparatus. A safety interlock prevents the actuation of the mixing blade in the event that the magnetic portion is not proximate to the first sensor. Overall, the apparatus is effective, fast, easy to operate, safe, and clean.
US09272249B2 Chemical feeder
The present invention relates to a chemical feeder that includes a housing (11) having a housing chamber (20) therein, a support plate (35) within the housing chamber that includes a plurality of support plate apertures (44), and a plurality of nozzles (69, 72) that each have a distributor head (78) that extends up through the support plate. Each distributor head distributes a feed liquid horizontally above the upper surface (38) of the support plate. The chemical feeder, with some embodiments, further includes a diverter plate (122) that extends upward from the support plate at an angle (125) of less than 90°. The diverter plate divides an upper housing chamber (146) into a first upper housing chamber (152) that includes solid chemical material, and a second upper housing chamber (155) that is free of solid chemical material.
US09272248B2 Gas separation composite membrane, and gas separating module, gas separation apparatus and gas separation method using the same
A gas separation composite membrane, containing a gas-permeable supporting layer and a gas separating layer containing a crosslinked polyimide resin over the gas-permeable supporting layer, in which the crosslinked polyimide resin has structure in which a polyimide compound is crosslinked and linked, and the polyimide compound is a copolymer having at least an imide group-containing monomer component and a monomer component having a specific polar group; and a module, a gas separation apparatus and a gas separation method using the same.
US09272247B2 Polyimide membranes
There is provided a membrane that includes a plurality of polyimide fibers encased in a fluoropolymer sheath, the plurality of fibers having a diameter of from about 10 nm to about 50 microns, wherein the plurality of fibers form a permeable non-woven mat. A method of manufacturing the membrane is provided.
US09272240B2 Method and device for purifying exhaust gases
The invention relates to a regenerative thermal postcombustion plant (24) used for purifying exhaust gas comprising hydrocarbons and nitrogen oxides, particularly for exhaust gas occurring during cement clinker production, by means of which the carbon compound is oxidized and the nitrogen oxides are thermally reduced while feeding in a nitrogen-hydrogen compound at a temperature of greater than 800° C. in the multistage combustion chamber (35).
US09272236B2 Filtration system
A filtration system for separating accompanying substances, present in liquid, droplet or mist form, from a gaseous material stream, comprising a housing, in which there is arranged a filter insert, wherein the housing has an inlet and an outlet for said material stream, wherein the filter insert comprises at least two filter layers, wherein one boundary surface of the first filter layer is essentially in parallel with a boundary surface of the second filter layer, wherein at least one boundary surface forms a barrier for said material stream.
US09272228B2 Full-duplex, wireless control system for interactive costumed characters
A control system for interactively operating a show control system (audio plus data) provided in a walk-around character costume. The system includes an interactive controller wearable with the walk-around character costume. The system includes an audio base station and a host controller communicatively linked to the audio base station. The interactive controller and the audio base station communicate via a wireless communications link. The control system includes a speaker controlled by the interactive controller, and the host controller transmits data over the wireless communications link via the audio base station including commands to play an audio file and an animation file, stored in memory accessible by the interactive controller, with the speaker. The control system includes microphones, linked to the interactive controller, capturing sounds near the walk-around character costume, and the interactive controller transmits the captured sounds over the communications link to the host controller via the audio base station.
US09272227B2 Flying toy spacecraft
A flying toy spacecraft having one or more low pressure channels acting as the primary lift mechanism. Each of the low pressure channels has a bottom member, two sidewalls, and an optional top member. The interior of the channel can be fitted with an airfoil or a trailing reflexed edge. In embodiments having two or more low pressure channels, the channels are spaced apart, thereby forming an inverted channel that stabilizes the flying toy spacecraft against undesired yawing motions.
US09272222B2 Method for providing a game, recording medium and server
A method for providing a game in which a plurality of missions is presented to a user device each time a certain period has elapsed from a server having a storage unit for storing user information relating to a plurality of users, includes the steps of generating a plurality of different missions for each of the plurality of users based on the user information stored in the storage unit, presenting a list of the generated missions for each of the users on the user device, and presenting an operational element for updating a mission included in the presented list to another mission regardless of the elapse of the period in accordance with the progress of presented missions.
US09272221B2 Method and apparatus for configuring an accessory device
The subject disclosure may include, for example, a method for determining a current performance of a gamer during a first gaming session of a gaming application, where the performance is determined from a first plurality of stimulus signals generated by a gaming accessory during the first gaming session according to a configuration setting assigned to the gaming accessory, identifying a prior performance of the gamer during a prior gaming session of the gaming application, where the prior performance is determined from a second plurality of stimulus signals generated by the gaming accessory according to the configuration setting, comparing the current performance to the prior performance to determine a change in performance of the gamer, and adjusting the configuration setting assigned to the gaming accessory according to the change in the performance of the gamer. Other embodiments are disclosed.
US09272218B2 Information processing system, information processing method, information processing program, computer-readable recording medium on which information processing program is stored
Provided is an information processing system with which a new function can be added without altering an application program itself. The information processing system includes: a first execution information obtaining unit configured to obtain first execution information which indicates an execution state of a first execution unit configured to execute an application program; an execution information storing unit configured to store the first execution information; and the first execution unit or a second execution unit configured to execute the application program, in which the first execution unit or the second execution unit uses the stored first execution information to execute the application program.
US09272211B2 Method and system to provide location-based competitive games, tournaments, prizes and high score reports via mobile devices
A system is provided for implementing a location specific gaming event having a server and databases for maintaining a plurality of user accounts and for maintaining location information. The server and databases maintain at least one affiliate account with at least one geographic location. The system is configured to receive at least one request from the at least one affiliate account to arrange for a location specific gaming event at the geographic location associated with the affiliate account. The system is further configured to receive at least one communication from mobile devices of at least two users when the mobile devices are located at the geographic location, the server of the system configured to administer the location specific gaming event to the users.
US09272209B2 Streaming interactive video client apparatus
An apparatus is described comprising a Power-over-Ethernet interface, a High-Definition Media Interface (HDMI), a Bluetooth interface, a means for decompressing low-latency streaming interactive video and audio from an Internet-based hosting service and outputting the decompressed audio and video through HDMI, and a means for transmitting to the Internet-based hosting service user control information and statistics from received packets. Further, the apparatus is able to receive two interleaved streams of low-latency streaming interactive video.
US09272206B2 System and method for playing an interactive game
An interactive treasure hunt game is provided. Game participants receive a card, map and/or identification badge configured with an RFID tag, bar-code or a magnetic “swipe” strip or the like. The RFID tag or other identifying device is used to store certain information identifying each play participant and/or describing certain powers or abilities possessed by an imaginary character that the card may represent. Players advance in the game by finding clues and solving various puzzles presented by the game. Players may also gain (or lose) certain attributes, such as magic skills, magic strength, fighting ability, various spell-casting abilities, etc. All of this information is preferably stored on the RFID tag or card so that the character attributes may be easily and conveniently transported to other similarly-equipped play facilities, computer games, video games, home game consoles, hand-held game units, and the like. In this manner, the game can seamlessly transcend from one play environment and/or entertainment medium to the next.
US09272203B2 Increasing the number of advertising impressions in an interactive environment
Increasing a number of advertising impressions in a system configured to facilitate user interaction with an interactive environment containing one or more advertising targets is described. A scene of a portion of the simulated environment is displayed from a camera point of view (camera POV) on a video display. The scene may change as the camera POV changes in response to movement of the camera POV along a camera path during the user's interaction with the simulated environment. Modifying the camera path or a camera field of view can place more of an advertising target within the scene displayed on the video display to increase a likelihood of generating an advertising impression compared to a likelihood of generating an advertising impression without the modification.
US09272202B2 Method and apparatus for tracking of a plurality of subjects in a video game
Method, computer program and system for tracking movement of a subject. The method includes receiving data from a distributed network of camera sensors employing one or more emitted light sources associated with one or more of the one or more camera sensors to generate a volumetric three-dimensional representation of the subject, identifying a plurality of clusters within the volumetric three-dimensional representation that correspond to motion features indicative of movement of the motion features of the subject, presenting one or more objects on one or more three dimensional display screens, and using the plurality of fixed position sensors to track motion of the motion features of the subject and track manipulation of the motion features of the volumetric three-dimensional representation to determine interaction of one or more of the motion features of the subject and one or more of the one or more objects on the three dimensional display.
US09272200B2 Sport court perimeter boundary
An improved court perimeter boundary for volleyball or other sports comprises at least one indicator that indicates a hypotenuse distance to be used in squaring the court delimited by the boundary. Optionally, the perimeter boundary may be separated, facilitating the setup of the court and the winding of the boundary for storage. A method of setting up a volleyball court is also described.
US09272199B2 System, method and apparatus for capturing and training a swing movement of a club
A system, method and apparatus for training a swing movement of a club includes storing a desired swing data in a measuring device, capturing a training swing data in the measuring device, comparing the training swing data to the desired swing data to determine a set of differential data, outputting a signal to a user corresponding to the set of differential data.
US09272195B2 Swing training device
A variety of swing training devices that are arranged to support a ball to be struck are described. At least one moveable object is positioned within a chamber located adjacent the ball support. The moveable object is arranged such that it can be seen by a hitter after the ball is struck when the hitter is looking at a point of contact where the ball is struck. The moveable objects are arranged to move when the ball is stuck and a variety of challenge games can be played that require the batter to identify something that happened to the moveable objects—thereby providing motivation to encourage the batter to focus his or her eyes on the region of contact.
US09272186B2 Remote adaptive motor resistance training exercise apparatus and method of use thereof
The invention comprises a method and/or an apparatus using a computer configured exercise system equipped with an electric motor to provide physical resistance to user motion in conjunction with means for sharing exercise system related data and/or user performance data with a secondary user, such as a medical professional, a physical therapist, a trainer, a computer generated competitor, and/or a human competitor. For example, the exercise system is used with a remote trainer to enhance exercise performance, with a remote medical professional for rehabilitation, and/or with a competitor in a competition, such as in a power/weightlifting competition or in a video game. The exercise system is optionally configured with an intelligent software assistant and knowledge navigator functioning as a personal assistant application.
US09272182B2 Exercise machine
An exercise device providing a fore and aft horizontal component of striding motion that is dynamically user-defined, while providing a vertical component of the motion that is maintained on a predetermined vertically reciprocating path in some embodiments. The exercise device guides the user's foot in a pseudo-elliptical stride path, while providing a dynamically variable stride length that allows the user to move with a natural stride length. The exercise device allows tall and short users to extend or curtail the stride length to match their natural stride lengths. The length of the reciprocating path is dynamically adjusted during the exercise operation without equipment adjustments by changes in the length of the stride input by the user at a pair of foot engagement pads disposed on laterally spaced apart foot support members.
US09272176B1 Multi-use apparatus for exercising the shoulder, upper and lower extremities
A multi-use exercise apparatus consisting of two stations, a wheel as the upper station for exercising upper extremities and a T-bar below the wheel as the lower station designed for resistance exercises of the lower extremities. Both stations are mounted on a collapsible structure making it easily transportable. Fixed knobs are disposed at various radii from an axis of the wheel to allow users to perform different ROM type exercises. Anchoring means are also provided on the apparatus to engage various other exercising accessories as well, either on the T-bar or adjacent to the wheel.
US09272170B2 Fire extinguishing system to eliminate smoldering/smoking of decomposed dried, former marshland, now peat, surrounded by water
A firefighting method and apparatus are described for suppressing fires in remote dried out former wetlands/marsh areas. A water pump is positioned upon a floating platform maneuverable in adjacent shallow marsh waters that are not navigable by conventional watercraft. Said pump has an intake port for drawing water from nearby marsh waters and ponds through a hose, said hose having a filtering screen for preventing the pickup of solid materials. The pump has a discharge hose connected to the outflow connection, said discharge hose connected on the distal end to a piping extension projecting away from the hull and over the nearby burning peat lands. Said pump is operated to discharge water over and into the adjacent burning marsh as the platform is maneuvered within the surrounding marsh canals and waterways.
US09272169B2 Fire barrier protection for airplanes comprising graphite films
A fire barrier system for use in aircraft, ship or offshore drilling platform comprises a flexible graphite sheet. Methods of providing fire barrier protection in an aircraft, ship or offshore drilling platform comprise installing the described fire barrier system in the aircraft, ship or offshore drilling platform. Additionally, the fire barrier system when installed in the aircraft, ship or offshore drilling platform is described.
US09272160B2 Tethered and/or visually coded brachytherapy devices and related methods
Bracytherapy devices include a respective tether attached to a proximal end portion of the strands. The tether can be color-coded to match a color associated with the corresponding strand.
US09272155B2 Leadless cardiac pacemaker with secondary fixation capability
The invention relates to leadless cardiac pacemakers (LBS), and elements and methods by which they affix to the heart. The invention relates particularly to a secondary fixation of leadless pacemakers which also include a primary fixation. Secondary fixation elements for LBS's may passively engage structures within the heart. Some passive secondary fixation elements entangle or engage within intraventricular structure such as trabeculae carneae. Other passive secondary fixation elements may engage or snag heart structures at sites upstream from the chamber where the LBS is primarily affixed. Still other embodiments of passive secondary fixation elements may include expandable structures.
US09272154B2 Computationally efficient technique for determining electrode current distribution from a virtual multipole
A system and method of providing therapy to a patient using a plurality of electrodes implanted within the patient. A virtual multipole configuration is defined relative to the plurality of electrodes. The distance between each of a group of the electrodes and a virtual pole of the virtual multipole configuration is determined. A stimulation amplitude distribution is determined for the electrode group based on the determined distances, thereby emulating the virtual multipole configuration. Electrical energy is conveyed from the electrode group in accordance with the computed stimulation amplitude distribution.
US09272153B2 VOA generation system and method using a fiber specific analysis
A system and method for generating an estimated volume of activation (VOA) corresponding to settings applied to a stimulation leadwire includes a processor performing the following: determining, for each of a plurality of neural elements, one or more respective parameters characterizing an electrical distribution along the neural element, looking up the one or more parameters for each of the neural elements in a look-up table (LUT), obtaining threshold values for each of the neural elements recorded in the LUT in association with the looked-up parameters, comparing, for each of the neural elements, a value of the leadwire settings to each of the respective threshold value, estimating based on the comparisons which of the neural elements would be activated by the settings, and generating a structure corresponding to a region including the neural elements estimated to be activated.
US09272152B2 Remote programming of MRI settings of an implantable medical device
A system and method are described herein including an implantable medical device (IMD) configured to be programmed with magnetic resonance imaging (MRI) settings for use during an MRI scan, wherein the IMD stores identity data that uniquely identifies the IMD or a patient having the IMD. The system includes an external storage media configured to receive MRI settings associated with the IMD and configured to store the MRI settings associated with the IMD. The system also includes a programmer configured to retrieve identity data from IMD, retrieve MRI settings associated with the IMD from the external storage media and program the IMD using the MRI settings.
US09272148B2 Combination of feedback on mechanical and electrical resynchronization to select therapy parameters
A system and method select a pacing site for a cardiac pacing therapy. A change from a baseline mechanical activity is extracted from a signal of mechanical heart activity during pacing at each one of multiple pacing sites along a heart chamber. A change from a baseline electrical activity is extracted from a signal of electrical heart activity during pacing at each of the of pacing sites. The pacing sites are sorted in a first order based upon the changes in mechanical heart activity and in a second order based upon the changes in electrical heart activity. A pacing site is selected from the multiple pacing sites as a common pacing site between the first order and the second order.
US09272146B2 Implantable medical device with active detection of atrial mechanical activity
A device includes a lead configured to for use in applying an atrioventricular delay (“AVD”), an acceleration sensor adapted to output an endocardial acceleration signal, and circuitry configured to receive and process said endocardial acceleration signal to provide ventricular pacing by varying, in a controlled manner, the AVD in a range having a plurality of AVD values. The circuitry derives from said endocardial acceleration signal a value of a parameter representative of an component of the endocardial acceleration signal corresponding to the first endocardial acceleration peak associated with an isovolumetric ventricular contraction (“EAX component”), and evaluates a degree of variation of said parameter values as a function of said plurality of AVD values to detect atrial and ventricular events.
US09272145B2 Timing control for paired plasticity
Systems, methods and devices for paired training include timing controls so that training and neural stimulation can be provided simultaneously. Paired trainings may include therapies, rehabilitation and performance enhancement training. Stimulations of nerves such as the vagus nerve that affect subcortical regions such as the nucleus basalis, locus coeruleus or amygdala induce plasticity in the brain, enhancing the effects of a variety of therapies, such as those used to treat tinnitus, stroke, traumatic brain injury and post-traumatic stress disorder.
US09272144B2 Lead electrode for use in an MRI-safe implantable medical device
An implantable stimulation system comprises a stimulator for generating electrical stimulation and a conductive stimulation lead having a proximal end electrically coupled to the stimulator, wherein at least a first component of the impedance looking into the stimulator is substantially matched to the impedance of the stimulation lead. At least one distal stimulation electrode is positioned proximate the distal end of the stimulation lead.
US09272142B2 Systems and methods for using a simplified user interface for hearing prosthesis fitting
The present application discloses systems and methods for displaying and operating a user interface having one or more channel group controllers corresponding to one or more groups of hearing prosthesis channels. The hearing prosthesis may be configured to generate a plurality of signals via a plurality of channels based on a channel profile. The channel profile may define at least one intensity level for each channel. In operation, the user interface may be configured to instruct the hearing prosthesis to change the channel profile of the plurality of channels in response to receiving an input via one of the channel group controllers. The user interface may be used to fit a hearing prosthesis to a recipient. In one embodiment, an initial channel profile may be automatically determined, and the prosthesis channel profile may be adjusted by changing a representative intensity level corresponding to the channel profile.
US09272135B2 Cable conductor fitting
Various embodiments concern a lead comprising a cable conductor and a coil electrode having one or more filars, the one or more filars wound in a helical pattern. The lead can further include an inner fitting axially aligned with the coil electrode. The inner fitting can comprise external threading and a slot extending along the inner fitting. The slot can receive a portion of the cable conductor. The lead can include an outer tubular fitting having a lumen with internal threading. Each of the coil electrode and the inner fitting can be partially received within the lumen, both of the external threading and the one or more filars threadedly engaged with the internal threading. The cable conductor can be pinched in the slot to mechanically connect the cable conductor to the inner fitting. The pinching can be supported by the outer tubular fitting.
US09272133B1 Methods of manufacturing devices for the neurorehabilitation of a patient
A mouthpiece for providing non-invasive neuromodulation to a patient, the mouthpiece including an elongated housing having an anterior region and a posterior region, the elongated housing having a non-planar exterior top surface and internal structural members disposed within the housing, the internal structural members elastically responding to biting forces generated by the patient, a spacer attached to the top surface of the housing for limiting contact between a patient's upper teeth and the exterior top surface of the elongated housing, and a printed circuit board mounted to a bottom portion of the elongated housing, the printed circuit board having a plurality of electrodes for delivering subcutaneous local electrical stimulation to the patient's tongue.
US09272130B2 Living body stimulating electrode, living body stimulating electrode apparatus, and method for producing living body stimulating electrode
Provided are a living body stimulating electrode, a living body stimulating electrode apparatus, and a method for producing a living body stimulating electrode. The living body stimulating electrode has a flexible circuit board (FPC) between a living body stimulating electrode and a resin part. The resin part and the FPC are fixed with the living body stimulating electrode. Specifically, the flexible circuit board is disposed between the living body stimulating electrode and the resin part, and one or both of a stimulating electrode and a contact electrode constituting the living body stimulating electrode have an engaging part having a pressing part and a fixing part. The pressing part presses the flexible circuit board onto the resin part. Simultaneously, the fixing part is penetrated through a through hole formed in the flexible circuit board and pressed into a hole formed in the resin part, thereby fixed to and held by the resin part. The engaging part may be subjected to a chamfering process (the edge may be chamfered into an angulated plane or a round plane) to form an inclined plane or a curved (round) plane.
US09272124B2 Systems and devices for selective cell lysis and methods of using same
A device for generating microbubbles in a gas and liquid mixture and injection device, the device comprising: a housing defining a mixing chamber; means for mixing solution contained in the mixing chamber to generate microbubbles in the solution; a needle array removably attached to the housing and in fluid connection with the mixing chamber, the needle array including at least one needle; and at least one pressure sensor for measuring tissue apposition pressure, the pressure sensor being mounted on one of the housing and the needle array.
US09272121B2 Side lumen reentry catheters and related methods
True lumen reentry devices and methods useable for redirecting a guidewire from a subintimal tract within a wall of a blood vessel into the true lumen of the blood vessel. A reentry catheter device comprises a main catheter shaft having at least one guidewire outlet aperture with at least one side tube located on a distal portion of the main catheter shaft. The side tube(s) is/are tracked over initially inserted guidewire(s) to advance a distal portion of the reentry catheter device into the subintimal tract with a guidewire.
US09272119B2 Methods for manufacturing non-prolapsing catheters with linerless tube
A method for manufacturing a catheter member having at least one lumen is disclosed herein. The method includes, winding a sacrificial coil over a mandrel in a first direction and winding a reinforcement coil over the sacrificial coil in a second direction. A polymer is then laminated over the sacrificial coil and the reinforcement coil. After the polymer is laminated, the mandrel is removed and the sacrificial coil is removed to thereby form the catheter member having the lumen.
US09272117B2 Intra-nasal aromatherapy clip
Described is an intra-nasal clip, and more particularly a nasal clip that diffuses the aromas or fragrances, such as those used in aromatherapy, of an aromatherapy sphere without irritation through direct contact with the inner nasal septum. The intra-nasal clip includes a bendable bridge extending between its outer distal ends, in which the distal ends comprise hollows with inlets. Aromatherapy spheres are within the hollows that contain aromatherapy materials.
US09272107B2 Chamber for housing animals during anaesthetic procedures
The present invention provides a chamber having at least one operator hand access port; the port comprising a port aperture located within the chamber wall; and at least two flexible non-resilient lightweight sealing gas-tight flaps(SFs), disposed the same plane of the port aperture in an overlapping manner, entirely enclosing the port aperture; each of the SFs is defined by a port aperture edge and chamber edges; the chamber edges are anchored to the chamber wall along more than half of the perimeter of the flap, at a distance from the center of the port greater than the radius of the port and beyond its perimeter; the port aperture edge of each flap is stretched across an entire chord of the port aperture; stretched port apertures edges define an interior access zone, disposed the same plane of the port aperture, characterized solely by the port aperture edges.
US09272102B1 Medicine box counter
Disclosed is a medicine box counter, which comprise a case body, comprising a bottom seat, an upper cap movably combined with the case body, and a plurality of resilient elements disposed between the bottom seat and the upper cap. As such, the medicine and the bottom seat are directly combined so that when the user exerts a pressure upon the upper cap in the use course, the resilient elements may be indirectly extruded and thus the bottom seat triggers the count mechanism to count, and after the pressure on the upper cap is released, the upper cap automatically restores to its original position by means of the resilient elements, whereby achieving the efficacies of rapid assembly, convenient use, effective medicine-taken count and reduced manufacturing cost are provided.
US09272100B2 Extended hub for a safety pen needle
A shielded pen needle assembly is provided in which the hub extends distally beyond an outer sleeve of the assembly.
US09272099B2 Syringe with visually coded needle hub
A medication delivery device included molded cylindrical barrel having visual marks on the surface of the barrel in the axial direction, a plunger seals the distal opening of the cylindrical barrel, a molded needle hub disposed in the proximal opening of the cylindrical barrel for sealing the needle hub to the barrel. A needle is disposed in the needle hub for communicating liquids by operation of the plunger in the axial direction. The circumferential surface on the flange of the needle hub comprises a colored mark that corresponds to a characteristic of the medication delivery device or its contents.
US09272096B2 Drive assembly for a drug delivery device and corresponding drug delivery device
A drive assembly for a drug delivery device is disclosed. The drive assembly is connectable with a cartridge holder and comprises a housing, a piston rod, the piston rod being movable in a distal direction for drug delivery, and a guide nut, the guide nut being rotatable relative to the housing around an axis of the assembly and provided for guiding the piston rod. A locking means is provided which is enabled to take an engaged state in which the locking means is engaged with the guide nut in order to prevent rotation of the guide nut and to take a disengaged state in which the locking means is disengaged from the guide nut in order to allow rotation of the guide nut. Moreover, a coupling means is provided, the coupling means being rotatable relative to the housing around the axis of the assembly for interaction with the locking means in order to change between the engaged state and the disengaged state of the locking means.
US09272094B2 Drug delivery device
The present invention relates to a drug delivery (5) comprising a housing (10) with a proximal end (28) and a distal end (22), a cartridge holder (14) adapted to retain a cartridge, the cartridge holder (14) being secured to the housing (10) and having an at least partially transparent side wall, and a cap (40) being capable of covering the distal end (22) of the drug delivery device, being rotationally fixed with respect to the housing (10) and comprising a window aperture (44), the window aperture (44) being capable of displaying information revealed by the cartridge holder (14). Furthermore, using a cap (40) for covering the distal end (22) of the drug delivery device (5) is disclosed.
US09272093B2 Dual drug pen-injection device with micro-reservoirs carrying secondary drug for emergency injection
An injection device to deliver at least two medicaments is disclosed where a first medicament is delivered in settable doses with a first medicament dose delivery mechanism and a second medicament is delivered from micro-reservoirs upon activation of a second medicament delivery system, whereby activation of the second medicament delivery system locks out the first medicament dose delivery mechanism.
US09272091B2 Posture state display on medical device user interface
The disclosure provides a system that displays a posture state indication to a user. A posture state indication represents the current posture state of the patient, which may be a combination of patient posture and activity. As a patient changes posture and activity throughout a daily routine, a posture state detector may generate a posture state value that may be used to categorize the patient's posture or posture and activity level as one of multiple posture states used to adjust therapy. The posture state may be associated with one of multiple posture state indications that may be presented to the patient. The posture state indication shows the patient the posture state currently detected by the posture state detector. The posture state indication may help the patient to effectively monitor therapy changes due to automatic, semi-automatic or patient-directed therapy adjustments made as a function of posture state.
US09272089B2 Differential pressure based flow sensor assembly for medication delivery monitoring and method of using the same
A differential pressure based flow sensor assembly and method of using the same to determine the rate of fluid flow in a fluid system. The sensor assembly comprises a disposable portion and a reusable portion. A flow restricting element is positioned along a fluid flow passage between an inlet and an outlet. The disposable portion further has an upstream fluid pressure membrane and a downstream fluid pressure membrane. The reusable portion has an upstream fluid pressure sensor and a downstream fluid pressure sensor. The upstream fluid pressure sensor senses the upstream fluid pressure at a location within the fluid flow passage between the inlet and the flow restricting element. The downstream fluid pressure sensor senses the downstream fluid pressure at a location within the fluid flow passage between the flow restricting element and the outlet. The process utilizes output of the sensors to calculate the flow rate of the fluid.
US09272086B2 Fluid management system
Fluid management systems and methods of operating fluid management systems which may provide one or more functions associated with suction, irrigation, distention, deficit monitoring, infusion, fluid warming, and the like. Some example embodiments may include infra-red lamps arranged to heat fluid flowing through a disposable cartridge. Some example embodiments may provide a three-dimensional fluid path through the cartridge and/or multi-stage heating capabilities. Some example fluid management systems may be selectable between pressure control and flow control modes.
US09272082B2 Pumping cassette
A pump cassette is disclosed. The pump cassette includes a housing having at least, one fluid inlet line and at least one fluid outlet line. The cassette also includes at least one reciprocating pressure displacement membrane pump within the housing. The pressure pump pumps a fluid from the fluid inlet line to the fluid outlet line. A hollow spike is also included on the housing as well as at least one metering pump The metering pump is fluidly connected to the hollow spike on the housing and to a metering pump fluid line. The metering pump fluid line is fluidly connected to the fluid outlet line.
US09272080B2 Flexible reduced pressure treatment appliance
A wound treatment appliance is provided for treating all or a portion of a wound. In some embodiments, the appliance comprises an impermeable flexible overlay that covers all or a portion of the wound for purposes of applying a reduced pressure to the covered portion of the wound. In other embodiments, the wound treatment appliance also includes a vacuum system to supply reduced pressure to the wound in the area under the flexible overlay. In yet other embodiments, the wound treatment appliance also includes wound packing means to prevent overgrowth of the wound or to encourage growth of the wound tissue into an absorbable matrix comprising the wound packing means. In still other embodiments, the appliance may include a suction drain. In other embodiments, the appliance may include a collection chamber to collect and store exudate from the wound. In yet other embodiments, a suction bulb may be used to provide a source of reduced pressure to an impermeable overlay that covers all or a portion of the wound. Finally, methods are provided for using various embodiments of the wound treatment appliance.
US09272077B2 Implantable materials having engineered surfaces and method of making same
An implantable biocompatible material includes one or more vacuum deposited layers of biocompatible materials deposited upon a biocompatible base material. At least a top most vacuum deposited layer includes a homogeneous molecular pattern of distribution along the surface thereof and comprises a patterned array of geometric physiologically functional features.
US09272070B2 Absorbent article
An absorbent article can include, in an immobilized form: a) microcapsules formed, in a proportion of at least 25% by weight relative to the total weight of polymer(s) forming the microcapsules, of a material derived from at least one natural polymer, a protein analog thereof, or a derivative thereof, and charged with at least one active agent, and b) at least one release agent that is capable of stimulating the dissolution of the microcapsules during the placing of the absorbent article in contact with an aqueous medium, and chosen from enzymes, surfactants that are water-soluble at room temperature and atmospheric pressure, and mixtures thereof, the microcapsules a) and the release agent b) being present in the said article in a form isolated from each other.
US09272067B2 Solid film, rapidly dissolvable in liquids
A solid film rapidly dissolvable in liquids, in particular biological liquids, to release pharmaceutical, cosmetic and nutrient substances. The solid film is also soluble in biological organic liquids to protect wounds of the human body by releasing cicatrizing, disinfectant and cosmetic substances. The film can also be used to release flavoring substances directly onto moist nutrient products.
US09272062B1 Air freshener and ornament
A combination air freshener and ornament has an ornament body and a support stand that serves dual purpose as a hanging hook when the ornament is in a hanging configuration and as a support stand when the ornament is in a standing display configuration. The support stand optionally has plugs at each end that removably engage with a receiving hole in the ornament body. The ornament body and/or the support stand are formed of fragranced polymer. One embodiment forms the ornament body in a gingerbread man configuration and the support stand in a candy cane configuration.
US09272060B2 Method for pre-treating preforms and blow molding apparatus for pre-treating and blow molding preforms into containers
A method for pre-treating preforms (12) made of thermoplastic plastic, before they are shaped into containers (13) by means of a stretch blow molding process and filled with liquid. The preforms (12) are tempered and sterilized for the subsequent stretch blow molding process. Tempering of the preforms (12) is carried out by means of microwave radiation and by sterilization of the preforms (12) during the pre-treatment.
US09272057B2 Combining radioimmunotherapy and antibody-drug conjugates for improved cancer therapy
Described herein are compositions and methods of use of radionuclide-antibody conjugates (for RAIT) and drug-antibody conjugates (ADC). The combination of RAIT and ADC was more efficacious than either RAIT alone, ADC alone, or the sum of effects of RAIT and ADC. The unexpected synergy resulted in decreased tumor growth rate and increased survival, with a high incidence of tumor-free survival in Capan-1 human pancreatic cancer xenografts in nude mice.
US09272055B2 Functionalized magnetic nanoparticles and use in imaging amyloid deposits and neurofibrillary tangles
The present disclosure provides functionalized magnetic nanoparticles (MNPs) comprising a functional group that binds to β-amyloid deposits and/or neurofibrillary tangles. The present disclosure provides compositions comprising the functionalized MNPs, and methods of using the functionalized MNPs in imaging β-amyloid deposits and neurofibrillary tangles.
US09272053B2 AAV-based treatment of cholesterol-related disorders
The invention in some aspects relates to methods and compositions for assessing the effectiveness of miRNA inhibitors. In other aspects of the invention, methods and compositions for treating cholesterol related disorders are provided. In one aspect of the invention, miRNA inhibitors against miR-122 and rAAV-based compositions comprising the same are provided.
US09272052B2 Synergistic effects between auristatin-based antibody drug conjugates and inhibitors of the PI3K-AKT mTOR pathway
The present invention is directed to methods for treating cancer comprising administering to a subject in need thereof an auristatin-based antibody drug conjugate and an inhibitor of the PI3K-AKT-mTOR pathway.
US09272050B2 MetAP-2 inhibitor polymersomes for therapeutic administration
Described herein are MetAP-2 inhibitors and compositions and formulations thereof, and more particularly compositions and formulations of MetAP-2 inhibitors wherein the MetAP-2 inhibitor is associated with a block copolymer comprising a hydrophilic polymer moiety and a hydrophobic polymer moiety. The present invention also relates to compositions and formulations comprising MetAP-2 inhibitors for oral administration or administration via routes such as topical or ocular administration. The present invention also provides methods to treat conditions associated with or related to the over-expression or over-activity of MetAP-2 by administering the compositions and formulations comprising MetAP-2 inhibitors as disclosed herein.
US09272047B2 Use of biological surfactant as anti-inflammatory agent and tissue preservative solution
The present invention relates to a use of a biological surfactant as an anti-inflammatory agent and a tissue preservative solution. More particularly, the present invention is directed to an anti-inflammatory agent and a tissue preservative solution comprising a biological surfactant which blocks a reaction of a proinflammatory factor with a receptor by emulsifying the proinflammatory factor.
US09272040B2 5-CNAC as oral delivery agent for parathyroid hormone fragments
Pharmaceutical compositions for the effective oral delivery of a parathyroid hormone, PTH, as well as methods for administration of the compositions are provided. Additionally, methods for stimulating new bone formation and treating and/or preventing osteoporosis are also provided.
US09272039B2 Structured non-aqueous gel-form carrier composition
Disclosed are non-aqueous carrier compositions capable of forming a gel structure, having a low molecular mass N-acyl glutamic acid diamide having a straight-chain alkyl group, a low molecular mass N-acyl glutamic acid diamide having a branched-chain alkyl group, at least one gel-promoting solvent, and at least one high molecular mass block copolymer having at least one hard segment and at least one soft segment, and at least one solvent capable of solubilizing the at least one hard segment and/or the at least one soft segment of the block copolymer, at least one oil-soluble polar modified polymer; and at least one solvent capable of solubilizing the at least one oil-soluble polar modified polymer, and optionally at least one active ingredient, wherein the composition has a hardness value ranging from about 30 to about 300 gf, a melting point of about 50° C. or higher, and does not require use of wax as a structuring agent. Methods of making and using the compositions are also disclosed.
US09272038B2 Wound care formulation
A gel formulation for use in filling a wound cavity and delivering active ingredient thereto, having a pH range of 6.5 to 7.5, low bioadhesive strength and cohesive integrity and being a PVA borate gel including an active ingredient and a modulator to bind borate and/or PVA in aqueous solution through a mono-diol or di-diol formation and reduces the pH of PVA-borate hydrogels. A suitable modulator is a sugar alcohol such as mannitol and the active ingredient, a medicament suitable for topical application such as a local anaesthetic and/or an antibiotic.
US09272034B2 Treatment of conditions related to shock
Techniques are disclosed for prevention or treatment of physiological shock by administering a specific therapeutic agent, which is able to use smaller volumes of reagent to achieve complete inhibition, than other previously described techniques.
US09272033B2 Methods and compositions for the prevention and treatment of kidney disease
The invention provides compositions for preventing or treating kidney disease comprising vitamin E, vitamin C, and a carotenoid and methods for preventing and treating kidney disease comprising administering such compositions to an animal susceptible to or suffering from kidney disease. In a preferred embodiment, the composition is admixed with one or more food ingredients to produce a food composition useful for preventing or treating kidney disease.
US09272032B2 Stabilized liquid anti-RSV antibody formulations
The present invention provides liquid formulations of SYNAGIS® or an antigen-binding fragment thereof that immunospecifically bind to a respiratory syncytial virus (RSV) antigen, which formulations exhibit stability, low to undetectable levels of aggregation, and very little to no loss of the biological activities of SYNAGIS® or an antigen-binding fragment thereof, even during long periods of storage. In particular, the present invention provides liquid formulations of SYNAGIS® or an antigen-binding fragment thereof which immunospecifically binds to a RSV antigen, which formulations are substantially free of surfactant, inorganic salts, and/or other common excipients. Furthermore, the invention provides method of preventing, treating or ameliorating symptoms associated with RSV infection utilizing liquid formulations of the present invention.
US09272026B2 HLA-A*1101-restricted WT1 peptide and pharmaceutical composition comprising the same
An HLA-A*1101-restricted WT1 peptide, specifically, a peptide comprising an amino acid sequence consisting of 9 contiguous amino acids from a WT1 protein, wherein the peptide has an ability to bind to an HLA-A*1101 molecule, and has an ability to induce a CTL is described. A peptide dimer having an ability to bind to an HLA-A*1101 molecule and having an ability to induce a CTL, in which two peptide monomers each comprising an amino acid sequence consisting of 9 contiguous amino acids from a WT1 protein and comprising at least one cysteine residue are bound to each other through a disulfide bond is also described. Furthermore, a polynucleotide encoding the peptide, a pharmaceutical composition for the treatment and/or prevention of a cancer comprising the same and the like are provided.
US09272025B2 Increased T-cell tumor infiltration and eradication of metastases by mutant light
Mutant LIGHT expressed in a tumor environment elicited high levels of chemokines and adhesion molecules, accompanied by massive infiltration of naïve T lymphocytes. Methods and compositions to elicit immune responses against tumors including tumor volume reduction and eradication of metastasis using mutant LIGHT are disclosed.
US09272023B2 Use of ixolaris, a tissue factor inhibitor, for inhibiting angiogenesis
The invention provides methods for treatment of tissue factor (TF) mediated or associated diseases or processes, such as cancer, by administering at least an active fragment of an Ixolaris polypeptide to a subject. The invention further includes identification of a subject in need of such treatment, and monitoring a subject for amelioration of at least one sign or symptom of the disease. The invention also features kits.
US09272021B2 Treatment of coagulation disease by administration of recombinant VWF
The present invention provides methods of treating coagulation disease, including hemophilia and von Willebrand disease by administering recombinant von Willebrand Factor alone or in combination with Factor VIII.
US09272020B2 IFN-beta compositions, preparation methods and uses thereof
The present invention pertains to interferon-beta (IFN-beta) compositions comprising interferon-beta and a grafted poly(glutamic acid) polymer having an average molecular weight between 26,000 and 40,000 g/mol, grafted with alpha-tocopherol substituents, the average molar grafting ratio being 4.5-5.5 moles %, the weight/weight ratio between said grafted poly(glutamic acid) polymer and IFN-beta being between 24 and 125. The present invention also pertains to the preparation methods of such compositions and their application to obtain therapeutic compositions in dosage unit form delivering IFN-beta over an extended period of time.
US09272017B2 Pharmaceutical compositions including a portion of the C-terminus of FGF23
The present invention is directed to a pharmaceuticalm composition comprising a peptide comprising at least a portion corresponding to the C-terminus of FGF23 and an additive selected from the group consisting of vitamin D and a vitamin D receptor agonist.
US09272016B2 Methods to enhance RNAi oligonucleotide delivery to respiratory epithelial cells
The present invention relates to methods of reducing a level of a target mRNA in a well-differentiated airway epithelial cell by contacting the cell with a sensitizing agent followed by contacting the cell with a therapeutic RNAi agent.
US09272009B2 Method for increasing performance of offspring
Methods and compositions for increasing intestinal transport of nutrients or growth performance in the offspring of an animal are described. More specifically, a feed composition comprising an omega-3 fatty acid-containing composition for increasing intestinal transport of nutrients or growth performance in the offspring of the animal, and methods therefor, are described.
US09271998B2 Method of inhibiting nonsense-mediated mRNA decay
Provided are methods for treating a NAD comprising administering to a patient suffering from a NAD a composition comprising an eIF5A inhibitor compound in an amount effective to prevent intracellular hypusination of eIF5A, whereby gene expression of NMD-susceptible mRNA is increased.
US09271996B2 Formulation and delivery of PLGA microspheres
The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity.
US09271992B2 Method for alleviating pain using sphingosine-1-phosphate and related compounds, and assays for identifying such compounds
Methods for alleviating pain comprising administering to a subject sphingosine-1-phosphate, functional fragments and derivatives thereof, and other compounds, and assays for identifying such compounds.
US09271989B2 Silicone-based composition for skin treatment
The present embodiments may relate to topically delivered compounded medications for the treatment of scar tissue, skin disorders, and/or other ailments. In one aspect, a transdermal cream or gel may provide for the effective administration of multiple medications simultaneously. Preferably, a silicone-based gel may be provided as a base composition and may have a non-zero percentage of silicone or silicone variant. The silicone-based gel may comprise cyclopentasiloxane, polysilicone-11, dimethicone, and C30-45 alkyl cetearyl dimethicone crosspolymer, and include several active ingredients, such as glucocorticoids, antihistamines, and nerve depressants. The silicone-based gel may include a combination of fluticasone, loratadine, and gabapentin. The concentrations of fluticasone and loratadine may be relatively low, while that of gabapentin moderately high. The silicone-based gel may also have one or more local anesthetics, such as prilocaine and/or lidocaine. The silicone-based gel may include additional active ingredients, such as NSAIDs, anticonvulsants, antidepressants, muscle relaxants, and/or other active ingredients.
US09271988B2 Combination therapy comprising a CDK4/6 inhibitor and a P13K inhibitor for use in the treatment of cancer
A combination of a CDK4/6 inhibitor and a P3Kinase inhibitor for the treatment of cancer.
US09271987B2 Methods and compositions for treating Alzheimer's disease
This disclosure relates to methods and compositions useful for treating Alzheimer's disease. In particular, the disclosure relates to pharmaceutical compositions containing an EGFR-inhibitory compound suitable for administration to treat Alzheimer's disease, as well as to related therapeutic methods. In addition, this disclosure relates to screening methods for identifying compounds useful for treating Alzheimer's disease based on the ability to inhibit the activity of EGFR.
US09271985B2 Method of using vasoconstrictive agents during energy-based tissue therapy
A mammal undergoing an energy-based therapy is treated by administering at least one vasoconstrictive agent to the mammal prior to or during the procedure. The at least one vasoconstrictive agent is added in amounts sufficient to reduce or prevent vasodilation. This treatment method increases or promotes the size of the coagulation zone created after energy-based therapy.
US09271984B2 Treatment of type 1 diabetes
The present invention relates to triazine derivatives of formula (I) for their use in the treatment of type 1 diabetes mellitus, and to compositions comprising said triazine derivatives.
US09271980B2 Deuterium-enriched pyrimidine compounds and derivatives
The present invention is concerned with deuterium-enriched pyrimidine compounds of formula I, their derivatives and pharmaceutically acceptable salts and methods of use thereof, The compounds of formula I are useful for the prevention and treatment of liver fibrosis and cirrhosis, hepatocellular carcinoma, neuroendrcrine neoplasia including metastasis and fibrosis fibrotic processes associated with neuroendocrine cell dysregulation for example Crohn's disease, pulmonary arterial hypertension, pulmonary hypertension associated with chronic obstructive pulmonary disease (COPD), right ventricular hypertrophy, pulmonary vascular remodeling, asthma, cystic fibrosis, hypertension, ischemic stroke, angina pectoris, congestive heart failure, arrhythmia, arterial fibrillation, gastrointestinal disorders, anxiety, depression, stress disorders, post-traumatic stress disorder, obsessive compulsive disorders, demyelinating diseases, acute or chronic cerebrovascular damage, cerebral infarction, subarachanoid hemorrhage, and cerebral edema, neuropathological diseases and cardiovascular system regulation.
US09271978B2 Heterocyclic compounds as bromodomain inhibitors
The present disclosure relates to compounds, which are useful for inhibition of BET protein function by binding to bromodomains, and their use in therapy.
US09271977B2 Sanglifehrin derivatives and methods for their production
There are provided inter alia compounds of formula (I) and (II) and their use in therapy, particularly for the treatment of viral infection.
US09271975B2 Compositions and methods for treating centrally mediated nausea and vomiting
Provided are compositions and methods for treating or preventing nausea and vomiting in patients undergoing chemotherapy, radiotherapy, or surgery.
US09271973B2 Methods of treating dermatological disorders and inducing interferon biosynthesis with shorter durations of imiquimod therapy
Pharmaceutical formulations and methods for the topical and/or transdermal delivery of imiquimod, including creams, ointments and pressure-sensitive adhesive compositions to treat dermatological disorders, namely, viral infections, such as Type I or Type II Herpes simplex infections and genital and perianal warts, actinic deratosis and superficial basal cell carcinoma, and to induce interferon biosynthesis to achieve an antiviral effect, with shorter durations of therapy, than currently approved for imiquimod by the Food & Drug Administration (“FDA”).
US09271966B2 Pharmaceutical compositions for the treatment of movement disorders
A pharmaceutical composition, medical food, dietary supplement or micronutrient for the treatment of a movement disorder comprising an NMDAR agonist or partial agonist as active ingredient therein in combination with a pharmaceutically acceptable carrier.
US09271964B2 Treatment using dantrolene
Provided are low-volume, safe for injection formulations of dantrolene yielding significant advantages over the currently approved and marketed dantrolene for malignant hyperthermia (MH) threatening anesthetic crisis. Once dantrolene can be made immediately available to patients triggered of MH, the anesthesiologist will be able to focus exclusively on the management of the patient's physiologic status in this complex and evolving crisis, not on the laborious and time consuming reconstitution process of the rescue agent. The low volume, safe for injection formulations of dantrolene have significant advantages over currently used approaches to the prevention and treatment of pumphead, and other neurological, cognitive and motor dysfunction incident to iatrogenically or trauma induced situations of altered blood flow, including those incurred during surgical procedures involving CPB or related procedures, as well as those incurred during non-normothermic episodes caused iatrogenically or by disease.
US09271956B2 Companion cosmetic compositions
A composition includes dihydroquercetin, α-tocopherol and bisabolol. The use of the composition in a cosmetic method for limiting, alleviating and/or preventing cutaneous discomfort, especially cutaneous discomfort induced by a disease or induced by a therapy, a radiotherapy treatment and/or chemotherapy treatment, and the process of manufacturing the composition are also described.
US09271955B2 Nutritional supplements for eye health and related methods
A nutritional or dietary supplement composition that strengthens and promotes a general eye health benefit for aging adults, including retinal health through the prevention, stabilization, reversal and/or treatment of visual acuity loss by reducing the risk of developing late stage or advanced age-related macular degeneration in persons with early age-related macular degeneration. The nutritional or dietary supplement composition may likewise reduce the risk of vision loss associated with the development of cataracts.
US09271952B2 Compositions and methods for treating nephropathy
Activated fatty acids, pharmaceutical composition compositions including activated fatty acids, methods for using activated fatty acids to treat nephropathy, and methods for preparing activated fatty acids are provided herein.
US09271948B2 Agent for improving vesicourethral dyssynergia
This invention is directed to an ameliorating agent for a disease based on vesicourethral dyssynergia, comprising, as an active ingredient, 3-(15-hydroxypentadecyl)-2,4,4-trimethyl-2-cyclohexene-1-one, a salt thereof, or a solvate thereof. The disease based on vesicourethral dyssynergia is any of dysuria accompanying a lifestyle-related disease (such as diabetic dysuria), idiopathic dysuria, dysuria after pelvic surgery, dysuria accompanying spinal cord injury, dysuria accompanying spinal canal stenosis, dysuria accompanying benign prostatic hypertrophy, dysuria accompanying high-pressure voiding/high-pressure urine storage, neurogenic or nonneurogenic lower urinary tract symptoms (LUTS), detrusor sphincter dyssynergia, and detrusor bladder neck dyssynergia.
US09271947B2 Use of propyl propane thiosulfinate and propyl propane thiosulfonate for the prevention and reduction of parasites in aquatic animals
A method for reducing parasites in aquatic animals is provided. The method includes reducing a plurality of parasites infecting an aquatic animal by administrating to the aquatic animal a compound comprising propyl propane thiosulfonate (PTSO) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 2. In yet a different embodiment, a method for reducing a plurality of parasites infecting an aquatic animal includes administrating to the aquatic animal a compound comprising and propyl propane thiosulfinate (PTS) having the formula R—SOa-S—R, where R represents n-propyl group (—CH2—CH2—CH3) and a is 1. In even yet another embodiment, a method for preventing a plurality of parasites in aquatic animals is provided and includes administrating to an aquatic animal a compound including PTS. In a different embodiment, a method for preventing a plurality of parasites in aquatic animals is provided and includes administrating to an aquatic animal a compound including PTSO.
US09271946B2 Use of a RAR antagonist or inverse agonist for the treatment of chemotherapy and/or radiation therapy side effects
A method for treating chemo therapy or radiation therapy side effects in a mammal undergoing chemotherapy and/or radiation therapy, the method comprising a step of administering to the mammal a therapeutically effective amount of a RAR antagonist or RAR inverse agonist which binds to receptors of the RARα, RARβ and RARγ subtypes is disclosed. Such side effects include chemoradiotherapy-induced alopecia, chemoradiotherapy-induced thrombocytopenia, chemoradiotherapy-induced leucopenia and chemoradiotherapy-induced neutropenia.
US09271944B2 Ketoprofen-containing aqueous adhesive skin patch
Provided is a water-based patch that contains ketoprofen as an active ingredient, provides high transdermal absorbability of the ketoprofen, and has high safety and high storage stability. The water-based patch contains the ketoprofen, an amine, and polyethylene glycol. In the water-based patch, the added amount of the ketoprofen in a paste is 0.1 to 5% by weight, the added amount of the amine in the paste is 0.5 to 10% by weight, and the added amount of the polyethylene glycol in the paste is 5 to 30% by weight. Particularly, in the water-based patch, diisopropanolamine is used as the amine.
US09271941B2 Pharmaceutical composition
Disclosed are novel pharmaceutical compositions containing N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)-6,8-dimethyl-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide dimethyl sulfoxide solvate, methods of using the compositions in therapy and processes for preparing the same.
US09271940B2 Immediate release pharmaceutical compositions comprising oxycodone and naloxone
The present invention pertains to oral immediate release pharmaceutical compositions suitable for treating patients suffering from pain comprising oxycodone and naloxone or their pharmaceutically acceptable salts.
US09271932B2 Fusogenic properties of saposin C and related proteins and peptides for application to transmembrane drug delivery systems
The present invention comprises a method for delivering pharmaceutical and/or imaging agents within and/or through the dermal, mucosal and other cellular membranes, and across the blood-brain barrier, utilizing a fusogenic protein. The fusogenic protein is associated with a phospholipid membrane, such as a liposome. The liposome may include dioleoylphosphatidylserine, a negatively charged long-chain lipid. Alternatively, the liposome is comprised of a mixture of negatively charged long-chain lipids, neutral long-chain lipids, and neutral short-chain lipids. Preferred fusogenic proteins include saposin C and other proteins, polypeptides and peptide analogs derived from saposin C. The active agent contained within the liposome may comprise biomolecules and/or organic molecules. This technology can be used for both cosmetic and medicinal applications in which the objective is delivery of the active agent within and/or beneath biological membranes or across the blood-brain barrier and neuronal membranes.
US09271928B2 Drug delivery composition
There is provided a non-water soluble drug delivery composition comprising a conjugate and a polymer matrix wherein exposure of the composition to electromagnetic radiation at a suitable pre-determined wavelength and intensity induces release of the active ingredient from the composition. The conjugate is attached to the polymer matrix through non-covalent interactions. There is also provided a drug delivery apparatus formed from the drug delivery composition.
US09271927B2 Formulation of drugs and vaccines in the form of percutaneous injectable needles
The invention relates to percutaneous administration of drugs and vaccines in form of solid penetrating needles, “injectable needles”, comprising a polymeric matrix resulting from the polymerization of a polymerizable paste or mixture. The injectable needles are hard enough to penetrate the skin and can be administered percutaneously by simple pusher or injector delivery devices. The manufacturing procedure of the injectable needles allows for the incorporation of the drug as preformulated stable microparticles and incorporation of modifying agents to modulate stiffness, solubility and drug release. Drugs formulated in these injectable needles offer a safe, simple and effective alternative to conventional percutaneous drug delivery systems based on hypodermic needles and syringes that require refrigerated storage and reconstitution prior to administration.
US09271926B2 Microfabricated nanopore device for sustained release of therapeutic agent
A drug delivery device that includes a capsule for implantation into the body; the capsule further includes a reservoir for containing a substance such as a therapeutic agent, at least one port for allowing the substance to diffuse from or otherwise exit the reservoir, and a nanopore membrane in communication with the capsule at or near the exit port for controlling the rate of diffusion of the substance from the exit port. The device also includes an optional screen for providing structural stability to the nanopore membrane and for keeping the pores of the nanopore membrane clear. One embodiment of the drug delivery device includes an osmotic engine internal to the device for creating fluid flow through the device.
US09271925B2 Multi-layer biodegradable device having adjustable drug release profile
Methods and apparatus for a biodegradable multi-layer device suitable for medical applications are provided, wherein the device is formed from multiple film-layers configured to have different characteristics from one another such as different release profiles for therapeutic agents, adhesive properties, stiffness properties, and solubility properties. The film-layers may include a solid fibrinogen component. A device having multiple film-layers may take a non-adherent form during delivery to a target location within or on tissue, and thereafter may be exposed to moisture to take an adherent form on the tissue. The device may include a number of additives, including materials to improve the mechanical properties of the device, or one or more therapeutic or contrast agents.
US09271917B2 Method and apparatus for delivery of a measured dosage of a non-aerosol, non-spray foam composition of minoxidil
A non-pressurized container that contains one or more of: a foamable composition of minoxidil, or a pharmaceutically acceptable salt thereof, and a dihydrotestosterone blocker in a formulation with a precise density and viscosity to yield a foam with a temperature sensitivity and shear strength designed for inverted application and immediate targeted release at body temperature under a minimal hand applied pressure to the scalp.
US09271914B2 Primecoat compositions for proteinaceous substrates and methods of priming proteinaceous substrates therewith
Compositions containing a solution of a polyfunctional aziridine component in a non-reactive solvent, and methods of applying such compositions to proteinaceous substrates, such as fingernails and toenails, to provide primed substrates which may be further coated.
US09271913B2 Structured depilatory compositions
Provided are compositions comprising a depilatory active; and a surfactant, wherein the composition has a Yield Stress of from about 1 Pascal (Pa) to about 1500 Pa, and methods of use thereof.
US09271912B2 Personal care compositions comprising a pH tuneable gellant and methods of using
A personal care composition is disclosed comprising a pH tuneable gellant. The pH tuneable gellant has a formula of: wherein R1 and R2 are aminofunctional end-groups; L1 is a backbone moiety having molecular weight from 14 to 500 g/mol; and at least one of L1, R1 or R2 comprises a pH-sensitive group; wherein R5 is an aminofunctional moiety; L2 is a backbone moiety having molecular weight from 14 to 500 g/mol; and at least one of L2 or R5 comprises a pH-sensitive group; and mixtures of [I] and [II]. The personal care composition may take a variety of forms such as a leave-on composition or an emulsion or may comprise one or more actives or agents.
US09271910B2 Dye composition comprising a cationic para-aminophenol oxidation base
The present invention relates to a para-aminophenol compound of formula (I) the addition salts thereof with an acid and the solvates thereof, dye composition comprising the latter and a dyeing process.
US09271909B2 Cleansing composition
A cleansing composition containing the following components (A) and (B): (A) an ether carboxylate of Formula (1) R1—O—(CH2CH2O)n—CH2—COOX (1) wherein —R1 represents a linear or branched C4-C10 alkyl or alkenyl group, —n represents a number from 0.5 to 20, and —X represents a hydrogen atom or a cation selected from the group consisting of an alkali metal, an alkaline earth metal, ammonium, an alkylammonium, an alkanolammonium, and a glucammonium; and (B) an ether carboxylate of Formula (2) R2—O—(CH2CH2O)m-CH2—COOY (2) wherein —R2 represents a linear or branched C12-C22 alkyl or alkenyl group, —m represents a number from 0.5 to 20, and —Y represents a hydrogen atom or a cation, selected from the group consisting of an alkali metal, an alkaline earth metal, ammonium, an alkylammonium, an alkanolammonium, and a glucammonium. R1—O—(CH2CH2O)n—CH2—COOX  (1) R2—O—(CH2CH2O)m—CH2—COOY  (2)
US09271905B2 Process for preparing polyurea microcapsules
The present invention relates to a process for producing perfume-containing microcapsules with a polyurea wall that can be used in home or personal care products, as well as to the microcapsules themselves and consumer products that contain these microcapsules. The process of the invention uses a combination of aromatic and aliphatic polyisocyanates in specific relative concentrations.
US09271903B2 Stable three-phased emulsions
Disclosed is a three-phase emulsion comprising an aqueous-gel outer phase comprising water and an emulsifier comprising a hydrophilic-lipophilic balance (HLB) value of 10 to 19; and a water-in-oil inner phase comprising water, an oil, and a silicone polyglucoside containing emulsifier, wherein the water phase of the water-in-oil inner phase does not include a salt.
US09271902B2 Whitening system capable of delivering effective whitening action
The invention provides a foamable composition for tooth bleaching which can be a one- or two-component system. The system has at least one peroxide compound, and at least one foaming agent. The composition can also contain at least one source of calcium, strontium and mixtures thereof, at least one de-sensitizing agent and at least one source of phosphate. The composition can produce a longer-lasting, collapsible foam structure with enhanced whitening action. The foamable composition can also be a one-component multi-phase system. A two-component composition can be packed in a two-compartment syringe. The syringe can also be fitted with a dispensing tip which may or may not have a static mixer.
US09271899B2 Methods, articles and kits for allergic desensitization, via the oral mucosa
Compositions and methods of use for desensitizing a subject to an allergen via regions of the oral mucosa are provided.
US09271897B2 Techniques for manufacturing ingestible event markers comprising an ingestible component
Method and systems for manufacturing a tablet comprising an electronic device are disclosed. In one method, a powdered material is provided into a die cavity of a tablet press and an electronic device is dispensed from a tape-and-reel carrier tape operatively coupled to the tablet press into the die cavity. The powdered material and the electronic device are compressing to form a tablet. A system comprises a tablet press comprising a die cavity for receiving a powdered material and an electronic device therein, an upper punch, and a lower punch. The upper and lower punches are operative to form the powdered material and the electronic device into a tablet. A tape-and-reel carrier tape is operatively coupled to the tablet press, where the carrier tape is configured for holding the electronic device. A transfer mechanism is used to transfer the electronic device from the tape carrier to the die cavity.
US09271896B2 Apparatus for weight based single doses of medication
An apparatus having a container comprising a volume. The volume is configured to retain a single dose of a medication appropriate for a specific classification of a weight of a patient. A first indicia is disposed on an exterior surface of the container. The first indicia indicates a type of the medication. A second indicia is disposed on the exterior surface. The second indicia indicates the specific classification, wherein the container, pre-packaged with the single dose, is appropriate for a single use dosing of the patient having the specific classification.
US09271893B2 Monocoque ambulation aid
Example ambulation aid apparatus and associated methods of manufacture are disclosed and described herein. An example ambulation aid apparatus includes an ambulation aid body formed as a integral part, the integral part formed in monocoque construction to provide support for mobility of a user through the integral part, the integral part providing a plurality of grippable areas to facilitate user movement and support through the integral part. Another example ambulation aid apparatus includes a primary panel formed in monocoque construction to provide support for and assist in mobility of a user through the skin of the monocoque primary panel, the primary panel formed to interrelate with one or more subassemblies to provide an integrated monocoque part to assist in providing support for and improved mobility of the user through the integrated monocoque part. Example methods of manufacture are also disclosed and described.
US09271891B2 Walker seat
A walker seat may include a seat bottom and a support structure. The seat bottom may include an anterior region, a posterior region, an upper side, and a lower side. The lower side may include a central segment retention portion. The support structure may include a central segment, a left-side segment, and a right-side segment. The central segment may be retained by the central segment retention portion. The left-side segment may be extendable from a left side of the central segment, whereby the left-side segment extends beyond a left side of the seat bottom. Similarly, the right-side segment may be extendable from a right side of the central segment, whereby the right-side segment extends beyond a right side of the seat bottom.
US09271889B2 Incapacitated patient lift device
A lifting system is provided for lifting a person who is incapacitated, where the lifting system includes a torso enclosure that may encase a substantial portion of the person's torso without requiring the person to slip one or both of their arms through the enclosure, and orthogonally-aligned structural straps positioned on the enclosure to stabilize and strengthen the enclosure during use, where portions of the straps are detached between two respective junction points to permit grasping of such straps by others when attempting to lift the incapacitated person.
US09271884B2 Personal storage accessory for wheelchairs
A transfer device for moving a personal storage container from a storage position at the rear of a wheelchair to a deployed position at a side of the wheelchair. The device includes a bracket adapted to be mounted to the backrest frame and a swivel mechanism with a first hinge leaf rotationally mounted to the bracket for rotation about a first axis and a second hinge leaf rotationally mounted to the first hinge leaf about a second axis spaced apart from the first axis. The second hinge leaf has a portion adapted to mount the personal storage container. The portion adapted to mount the personal storage container moves along an arc contained within a plane between the storage and the deployed positions, and the first and second axes are normal to the plane. A personal storage container assembly is also provided.
US09271879B2 Article having a seal and process for forming the same
An article having an embossed seal includes at least two webs, and an embossed seal joining a portion of the at least two webs, the seal including co-registered concentric discrete extended elements formed in the at least two webs, the discrete extended elements having open proximal ends.
US09271878B2 Apparatus for manufacturing absorbent article and method for manufacturing absorbent article
An apparatus for manufacturing an absorbent article includes a guide member that guides an elastic member fed on a web configuring a component of the absorbent article and being conveyed in a continuous state. The guide member includes: an arm member having a tip portion that is a feeding position of the elastic member to the web, and a base portion separated from the tip portion; a first drive member that swings the arm member about the base portion of the arm member as a rotational axis; and a second drive member that performs a back and forth movement of the arm member and the first drive member along a cross direction that crosses a conveyance direction in which the web is conveyed.
US09271876B2 Sealing film dressing
Provided is a film dressing that includes a thin plastic film coated with an adhesive, and a carrier layer applied on the plastic film on a side opposite to the adhesive coating. The adhesive coating has a softness of 10-22 mm and a weight per unit area of 50 g/m2 or more.
US09271875B2 Thermally conductive, metal-based bandages to aid in medical healing and methods of use
The inventive disclosure contained herein is generally directed to a class of medical bandages that in many embodiments are effective in the treatment of various types of tissue burns, whether be burns due to thermal burns, sun exposure, or rashes. Such products can include a plurality of specialized bandages and wraps that incorporate an extremely thin layer of thermally conductive metal (often aluminum) at the base of a substrate adapted to be in direct contact with a burn wound, while manufacturing the top side of the aluminum substrate to have a heat-dissipation-enhancing topography to help cool burns faster by enhancing thermal-convection properties. The bandage can also feature a thermochromic indicator for users to realize the thermal-cooling status of a burn to which a bandage has been applied.
US09271874B2 Support for an absorbent article
A reusable sheath-like support for use with absorbent articles, and specifically used with ostomy appliances. The absorbent article provides an additional level of security and comfort to an ostomate already utilizing a two-piece or one-piece ostomy appliance of the type which is secured to the body with a faceplate. The faceplate provides an adhesive securement means such as a hydrocolloid adhesive member or a combination of hydrocolloid adhesive member and an integral or non-integral adhesive non-woven fabric or adhesive tape.
US09271873B2 Film dressing comprising an application aid
The present disclosure relates to a film dressing having a polymer film and an application system for permitting an improved ease of use of said film dressing. The application system is located on the first side of the polymer film and has at least one first and one second supporting film. At least one first grip strip is formed on the first supporting film and at least one second grip strip is formed on the second supporting film. At least the first grip strip has a grip surface that enables the grip strip to be grasped and the first grip strip at least partially overlaps the second grip strip.
US09271871B2 Face protector lens assembly and method of use
A retainer lens of shape and dimensions configured to be releasably secured in the front opening of a face plate or helmet has a window opening configured for positioning in front of the eyes of a wearer of the face plate or helmet. An outer protective cover is configured to be secured over the window opening by means of scrap-book like frame corners located on the front surface of the retainer lens and spaced outwardly from respective corners of the window opening. The corners of the outer protective cover are releasably engaged with respective frame corners, so that the cover can be removed from the outside of the face plate as needed for replacement with a new outer protective cover, simply by removing the corners of the current outer protective cover from the respective frame corners, and then engaging a new outer protective cover into the frame corners.
US09271870B2 Apparatus for patterned plasma-mediated laser ophthalmic surgery
A system for ophthalmic surgery on an eye includes: a pulsed laser which produces a treatment beam; an OCT imaging assembly capable of creating a continuous depth profile of the eye; an optical scanning system configured to position a focal zone of the treatment beam to a targeted location in three dimensions in one or more floaters in the posterior pole. The system also includes one or more controllers programmed to automatically scan tissues of the patient's eye with the imaging assembly; identify one or more boundaries of the one or more floaters based at least in part on the image data; iii. identify one or more treatment regions based upon the boundaries; and operate the optical scanning system with the pulsed laser to produce a treatment beam directed in a pattern based on the one or more treatment regions.
US09271865B2 Hot and cold eye treatment apparatus
An eye treatment apparatus includes a hot and cold eye mask and a recirculating water cooling system. The eye mask includes a water pack to be applied onto human eyes, a thermoelectric cooling device for heating or cooling liquid of the water pack, a heat transfer member interposed between the water pack and one side of the thermoelectric cooling device, and a heat exchanger attached to the other side of the thermoelectric cooling device. The thermoelectric cooling device is configured to heat or cool the water pack through the heat transfer member. The water cooling system includes a water supply container and a conduit connecting the water supply container and the heat exchanger to circulate water from the water supply container to the heat exchanger and to return water from the heat exchanger to the water supply container.
US09271864B2 Orthosis for range of motion, muscular and neurologic rehabilitation of the lower extremities
A non-invasive apparatus for rehabilitating a joint, limb, and muscles of a patient recovering from surgery on the joint, includes a continuous passive motion device having at least one support member for supporting the limb, at least one hinge coupled to the at least one support member, and at least one actuator for providing reciprocating motion of the at least one support member about the at least one hinge, a plurality of electrodes transmitting at least four modalities chosen from a group consisting of functional electrical stimulation (FES), transcutaneous electrical nerve stimulation (TENS), temperature therapy stimulation, deep vein thrombosis (DVT) prophylactic stimulation, venous blood flow monitoring, and pain monitoring, and a control unit controlling the at least one actuator and the plurality of electrodes according to a coordinated sequence of the reciprocating motion and transmission of the at least four modalities.
US09271861B1 Device and method of treating a nail condition
A device and method for treating an ingrown nail condition is provided. The device prevents a solution that is applied during a procedure from coming into contact with the surrounding skin and nail bed. The device includes a plastic tube that has a flap located at one end. An applicator is inserted through the tube to ensure direct application of a phenol or similar solution onto only a nail matrix. As a result, the phenol or similar solution is prevented from coming into contact with the surrounding skin and nail bed, thereby reducing post-operative healing time, post-operative infection and post-operative pain.
US09271856B2 Delivery catheter with distal moving capsule for transapical prosthetic heart valve delivery
Heart valve delivery systems and methods of delivering and implanting heart valves using delivery catheters are disclosed. The delivery systems can include a handle assembly with a rotatable control knob and a catheter including an introducer shaft, an intermediate shaft extending from the handle assembly, an inner shaft extending from the handle assembly, and a capsule for containing a prosthesis. The distal end of the capsule can be connected to a distal end of the inner shaft, which can be moved in a distal direction by the rotatable control knob to deploy the prosthesis. By advancing the introducer through the deployed prosthesis and retracting the capsule to mate with the introducer, a smooth profile can be created for retraction of the system through the deployed prosthesis, minimizing hang-ups and snagging.
US09271855B2 Catheter having hydraulic actuator with tandem chambers
Catheter including an inner tubular member having a fluid lumen defined therein and an exterior surface. The exterior surface defining a first distal flow port and a second distal flow port. An outer tubular member is movable relative to the inner tubular member in a proximal direction and having an interior surface. A first pressure chamber is defined between the exterior surface and the interior surface, and between a first distal seal assembly and a first proximal seal assembly. A second pressure chamber is defined between the exterior surface and the interior surface, and between a second distal seal assembly and a second proximal seal assembly. Fluid introduced through the fluid lumen pressurizes the first pressure chamber and the second pressure chamber to generate a respective force at the first proximal seal assembly and to the second proximal seal assembly to urge the outer tubular member in the proximal direction.
US09271854B2 Collapsing structure for reducing the diameter of a stent end
A collapsing structure for collapsing the crowns of a stent and method of use thereof are described. The collapsing structure comprises an inner filament engaged to an outer filament. The outer filament is interwoven through at least a portion of the crowns of the stent end so as to create a plurality of loops. The inner filament is interwoven through at least a portion of the loops of the outer filament. Pulling on the inner filament causes the loops of the outer filament to be pulled radially inward, thereby pulling the crowns towards each other to collapse the stent end.
US09271853B2 Vascular stents and related methods
A vascular stent assembly includes at least a first and a second strut, each including a thickness and a depth. The assembly includes a pair of end radii, with each of the first and second struts extending from one of the pair of end radii. A thickness of at least one of the first and second struts includes a tapering profile extending from one of the end radii to another of the end radii, the tapering profile following a continuously increasing or decreasing function through at least half a length of the at least one strut.
US09271849B2 Method and system for identification of a center of a patient's body part
An apparatus for locating a central axis of a spinal column and method of using the same is disclosed. The apparatus and method includes one or more members capable of spanning a center line which may then be identified by at least one additional member positioned therebetween. Furthermore, the device may contain or be capable of accommodating various additional tools for marking the location of the central axis of a spinal column.
US09271848B2 Prosthetic joint component planning template
A method for planning the implantation of a prosthetic joint component in a prosthesis-receiving bone is described. Surrounding soft tissue is retracted to expose the prosthesis-receiving bone. A prosthetic joint component planning template comprising a planar template body having a unitary structure is provided. The planning template is positioned in a superimposed orientation with a curvilinear surface of an exposed prosthesis-receiving bone. The position of the planning template is adjusted into a desired superimposed orientation with respect to the prosthesis-receiving bone. At least one of a size and an orientation of the prosthetic joint component is determined through visualization of the planning template and the prosthesis-receiving bone. An apparatus for assisting a user with determining at least one of a size and an orientation of a prosthetic joint component is also provided.
US09271847B2 System and method for facilitating hip surgery
A system and method for use during hip surgery includes a position frame that is removably secured to the patient's femur. The system further includes a tracking unit and navigation engine that establish a pelvic coordinate system and, with the patient's leg placed in a predetermined orientation, capture the location of the femoral position frame within the pelvic coordinate system. The system further includes an image generator configured to display one or more images for directing the surgeon to return the patient's leg to the predetermined orientation following a trial reduction based upon the previously captured position. A leg change determination engine compares the current, post-reconstruction position of the femoral position tracking frame with the previously captured, pre-reconstruction position to derive leg length, offset, and anterior-posterior change values. The change values are then provided to the surgeon for evaluating the suitability of the trial reduction.
US09271846B2 Expanding interbody implant and articulating inserter and method
A device to space vertebral members with first and second members that may have at least one ramped section. The first and second members may be positioned in a vertically overlapping arrangement with interior sides of the members facing together. The device may be positionable between a first orientation with the ramped section of the first member positioned away from the ramped section of the second member, and a second orientation with the ramped section of the first member positioned against the ramped section of the second member. The device may include a greater height measured between the exterior sides in the second orientation than in the first orientation.
US09271845B2 Programmable implants and methods of using programmable implants to repair bone structures
Various embodiments of implant systems and related apparatus, and methods of operating the same are described herein. In various embodiments, an implant for interfacing with a bone structure includes a web structure, including a space truss, configured to interface with human bone tissue. The space truss includes two or more planar truss units having a plurality of struts joined at nodes. Implants are optimized for the expected stress applied at the bone structure site.