Document Document Title
US09035111B2 Method for producing fluorinated organic compounds
A method for producing fluorinated organic compounds, including hydrofluoropropenes, which preferably comprises converting at least one compound of formula (I): CF3(—CX2X2)nCX1═H2  (I) to at least one compound of formula (II): CF3(CX2X2)nCX1═H2  (II), where X1 is Cl, Br or I, each X2 is independently selected from the group consisting of H, Cl, F, Br or J, and n is 0, 1, or 2.
US09035109B2 Process for production of hexamethylenediamine from carbohydrate-containing materials and intermediates therefor
Processes are disclosed for the conversion of a carbohydrate source to hexamethylenediamine (HMDA) and to intermediates useful for the production of hexamethylenediamine and other industrial chemicals. HMDA is produced by direct reduction of a furfural substrate to 1,6-hexanediol in the presence of hydrogen and a heterogeneous reduction catalyst comprising Pt or by indirect reduction of a furfural substrate to 1,6-hexanediol wherein 1,2,6-hexanetriol is produced by reduction of the furfural substrate in the presence of hydrogen and a catalyst comprising Pt and 1,2,6-hexanediol is then converted by hydrogenation in the presence of a catalyst comprising Pt to 1,6 hexanediol, each process then proceeding to the production of HMDA by known routes, such as amination of the 1,6 hexanediol. Catalysts useful for the direct and indirect production of 1,6-hexanediol are also disclosed.
US09035108B2 Method for preparing chlorohydrins composition and method for preparing epichlorohydrin using chlorohydrins composition prepared thereby
Provided are a method of preparing a chlorohydrin composition and a method of preparing epichlorohydrin by using a chlorohydrin composition prepared by using the method. The method of preparing chlorohydrins in which polyhydroxy aliphatic hydrocarbon is reacted with a chlorination agent in the presence of a catalyst includes performing at least one combination of a series of unit operations comprising a first reaction step, a water removal step, and a second reaction step in this stated order, wherein the method further includes mixing a chlorohydrin concentrate obtained by purifying the reaction mixture discharged from the final reaction step from among the reaction steps and a water-rich layer discharged from the water-removal step and diluting the mixture with water. The method of preparing epichlorohydrin includes contacting the chlorohydrin composition prepared by using the method of preparing a chlorohydrin composition with an alkaline agent.
US09035105B2 Process for the in situ production of polyether polyols based on renewable materials and their use in the production of flexible polyurethane foams
A polyether polyol based on renewable materials is obtained by the in situ production of a polyether from a hydroxyl group-containing vegetable oil, at least one alkylene oxide and a low molecular weight polyol having at least 2 hydroxyl groups. The polyol is produced by introducing the hydroxyl group-containing vegetable oil, a catalyst and an alkylene oxide to a reactor and initiating the alkoxylation reaction. After the alkoxylation reaction has begun but before the reaction has been 20% completed, the low molecular weight polyol having at least 2 hydroxyl groups is continuously introduced into the reactor. After the in situ made polyether polyol product having the desired molecular weight has been formed, the in situ made polyether polyol is removed from the reactor. These polyether polyols are particularly suitable for the production of flexible polyurethane foams.
US09035104B2 Process for making polyglycerol ethers of fatty alcohols
Disclosed are processes relating to the production of polyglycerol ethers of fatty alcohols, in particular, one step process using fatty alcohol and glycerine to synthesize polyglycerides of fatty alcohols will provide a 100% renewable surfactant that is cost effective efficient and CMR free. The synthetic methods mentioned in prior art uses hazardous chemicals as glycidyl ethers, epichlorohydrin that are listed as CMR and known carcinogens and hazardous to handle.
US09035102B2 Hydrolysis of the residues obtained in the production of isophorone to recover isophorone and acetone
A process for preparing isophorone (3,5,5-trimethyl-2-cyclohexen-1-one) is provided wherein distillation vapors from the work-up of product fractions are recycled to earlier stages of operation of the process.
US09035100B2 Method for producing phenylphosphonic acid metal salt composition, and crystal nucleating agent therefrom
A method for producing a phenylphosphonic acid metal salt composition, including reacting a phenylphosphonic acid compound (a) with a metal salt, metal oxide or metal hydroxide (b) that is present in an amount beyond the equivalent, the phenylphosphonic acid metal salt composition containing phenylphosphonic acid metal salt, and a surplus amount of the metal salt, the metal oxide or the surplus metal hydroxide (b). A crystal nucleating agent comprises the phenylphosphonic acid metal salt composition produced by the method.
US09035099B2 Process for making ethoxylated amine compounds
An improved process for making ethoxylated amine compounds such as ethanolamines. The improvement comprises the addition of an acid to the amine compound prior to the addition of ethylene oxide to a reactor wherein the ethoxylated amine compound is prepared. The improvement reduces the concentration of undesirable glycol ether and/or vinyl ether ethoxylate byproducts which may contribute to undesirable properties, such as color and foaming, of the ethoxylated amine compounds.
US09035096B2 CCR9 inhibitors and methods of use thereof
The invention relates to compounds represented by Structural Formula I, which can bind to CCR9 receptors and block the binding of a ligand (e.g., TECK) to the receptors. The invention also relates to a method of inhibiting a function of CCR9, and to the use compounds represented by Structural Formula I in research, therapeutic, prophylactic and diagnostic methods.
US09035094B2 Process for production of adipic acid from 1,6-hexanediol
Processes are disclosed for the conversion of 1,6-hexanediol to adipic acid employing a chemocatalytic reaction in which 1,6-hexanediol is reacted with oxygen in the presence of particular heterogeneous catalysts including at least one of platinum or gold. The metals are preferably provided on a support selected from the group of titania, stabilized titania, zirconia, stabilized zirconia, silica or mixtures thereof, most preferably zirconia stabilized with tungsten. The reaction with oxygen is carried out at a temperature from about 100° C. to about 300° C. and at a partial pressure of oxygen from about 50 psig to about 2000 psig.
US09035093B2 Methods for production of high concentration of arginine bicarbonate solution at high pressure
Methods of producing arginine bicarbonate solutions in very high concentrations including reacting an arginine slurry containing a first portion of arginine with a source of carbon dioxide gas at elevated pressure and temperature, adding subsequent portions of arginine to the resulting solution and further reacting with compressed carbon dioxide until a final solution containing in excess of 50% by weight are provided which include preparing an arginine solution by subjecting an arginine water slurry to elevated pressure and temperature and reacting the arginine solution with a source of carbon dioxide gas to form a solution comprising arginine and bicarbonate anion and recovering arginine bicarbonate from the solution.
US09035092B2 Process for the (AMM)oxidation of lower molecular weight alkanes and alkenes
A process for producing unsaturated carboxylic acids or unsaturated nitriles by vapor phase oxidation reaction of their corresponding C3 to C5 alkanes, C3 to C5 alkenes, and mixtures thereof, as a hydrocarbon starting material, wherein the process performance is monitored and the path of gasses through catalyst beds is altered. Improved catalyst lifetimes may be achieved.
US09035084B2 Preparation method of aromatic boronate compounds
Preparation method of aromatic boronate compound is provided, in which the is as follows: reacting aromatic amine Ar-NH2, with diboronic ester and alkyl nitrite in the presence of organic solvent, where Ar represents non-heterocyclic aryl. It enables for the first time the preparation of aromatic boronate from aromatic amine in one step by the present method.
US09035081B2 Synthesis of phosphinimide coordination compounds
Methods to make R13P═N—TiCl3 and (1-R2-Indenyl)Ti(N═PR13)Cl2, where R1 is independently selected from C1-30 hydrocarbyl radical which is unsubstituted or further substituted by one or more halogen atom, a C1-8 alkoxy radical, a C6-10 aryl radical, a C6-10 aryloxy radical, an amido radical, a silyl radical, and a germanyl radical; P is phosphorus; N is nitrogen (and bonds to the metal M); R2 is a substituted or unsubstituted alkyl group, a substituted or an unsubstituted aryl group, or a substituted or unsubstituted benzyl group, wherein substituents for the alkyl, aryl or benzyl group are selected from alkyl, aryl, alkoxy, aryloxy, alkylaryl, arylalkyl and halide substituents. The method to make R13P═N—TiCl3 combines a titanium species TiCl3(OR) where R is an alkyl or aromatic group, with a trimethylsilyl phosphinimide compound R13P═N—SiMe3 in the presence of solvent, to give the titanium complex R13P═N—TiCl3. The method to make (1-R2-Indenyl)Ti(N═PR13)Cl2 consists of deprotonating 1-R2-indene with an appropriate base, followed by reaction with R13P═N—TiCl3.
US09035079B2 Method for cleaving unsaturated fatty chains
The invention relates to a method for cleaving unsaturated fatty chains comprising a step of oxidative cleavage in which at least one fatty acid derivative having at least one unsaturation is reacted in the liquid phase with hydrogen peroxide in the presence of a catalyst for activating the reaction of oxidative cleavage and of molecular oxygen and in the absence of organic solvent.
US09035076B2 Recovery of lactic acid values from a meso-lactide stream
Lactic acid equivalents are recovered from a starting lactide stream by catalytically racemizing a portion of the lactide in the stream at a temperature of 180° C. or below. This increases the proportion of two species of lactide (i.e., at least two of S,S-, R,R- or meso-lactide) at the expense of the third species. The racemized mixture so obtained can be separated to recover some or all of one or more of the lactide species from the remaining lactide species, by a process such as melt crystallization or distillation. Impurities in the starting lactide stream usually are retained mostly in the remaining meso-lactide, so a highly purified S,S- and/or R,R-lactide stream can be produced in this manner. Such a purified S,S- and R,R-lactide stream is suitable for polymerization to form a polylactide.
US09035074B2 Pyrrolo[2,3-D]pyrimidine derivatives
Described herein are pyrrolo{2,3-d}pyrimidine derivatives, their use as Janus Kinase (JAK) inhibitors, and pharmaceutical compositions containing them.
US09035071B2 Compounds acting at multiple prostaglandin receptors giving a general anti-inflammatory response
The present invention provides a compound that is represented by the following general formula wherein R1, R2, R4, R5, R6, R7, X, W, X and Y are as defined in the specification. The compounds may be administered to treat DP1, FP, EP1, TP and/or EP4 receptor mediated diseases or conditions.
US09035068B2 Phosphohistidine analogs
The present invention relates to the phosphohistidine analogs of the present invention which of the formula (I) and the hapten containing the residue of same. It also relates to the hapten conjugated to a carrier molecule and the isolated antibodies raised against the immunogens, said antibodies recognizing polypeptide containing a phosphorylated histidine or the phosphotriazole residue but it does not recognize an amino acid or polypeptide that is not phosphorylated or a polypeptide which is phosphorylated on amino acids other than histidine but not on histidine.
US09035065B2 Ethanamine compounds and methods of using the same
The present invention is directed to ethanamine compounds, pharmaceutical compositions comprising the same, and methods of treating depression by administering the ethanamine compound.
US09035064B2 N-(1,2,5-oxadiazol-3-yl)pyridinecarboxamides and use thereof as herbicides
A description is given of N-(1,2,5-oxadiazol-3-yl)pyridinecarboxamides of the general formula (I) as herbicides. R in this formula (I) stands for radicals such as hydrogen, organic radicals, and other radicals such as halogen. W stands for a substituted pyridyl radical.
US09035058B2 Synthesis of MSE-framework type molecular sieves
A method of synthesizing a crystalline molecular sieve having an MSE framework type comprises crystallizing a reaction mixture comprising a source of water, a source of an oxide of a tetravalent element, Y, selected from at least one of silicon, tin, titanium, vanadium, and germanium, optionally a source of a trivalent element, X, a source of an alkali or alkaline earth metal, M, and a source of organic dications, Q, such as 3-hydroxy-1-(4-(1-methylpiperidin-1-ium-1-yl)butyl)quinuclidin-1-ium, 3-hydroxy-1-(5-(1-methylpiperidin-1-ium-1-yl)pentyl)quinuclidin-1-ium, 1,1′-(butane-1,4-diyl)bis(1-methylpiperidin-1-ium), 1,1′-(pentane-1,5-diyl)bis(1-methylpiperidin-1-ium), 1,1′-(hexane-1,6-diyl)bis(1-methylpiperidin-1-ium), and 1,1′-((3as,6as)-octahydropentalene-2,5-diyl)bis(1-methylpiperidin-1-ium).
US09035057B2 Dihydroethidine analogues and uses thereof
Tracers for imaging distribution of reactive oxygen species (ROS) are disclosed. The tracers include radiolabeled dihydroethidine (DHE) analogues. Further disclosed are uses of the compounds, including methods of imaging tissue distribution of ROS in vivo by positron emission tomography (PET). Methods of synthesizing the compounds are also disclosed.
US09035052B2 Compositions of azimilide dihydrochloride
The present invention is directed to solvates and various polymorphic forms of (E)-1-[[[5-(4-chlorophenyl)-2-furanyl]methylene]amino]-3-[4-(4-methyl-1-piperazinyl)butyl]-2,4-imidazolidinedione dihydrochloride and pharmaceutical compositions thereof.
US09035051B1 Ghrelin O-acyl transferase inhibitor
The present invention provides novel GOAT inhibitors and their salts and pharmaceutical compositions thereof.
US09035049B2 Herbicidal compounds
The present invention relates to novel herbicidal compounds of Formula (I), or an agronomically acceptable salt of said compound wherein R1, R2, A1, Ra, Rb, Rc and Rd are as defined herein. The invention further relates to compositions which comprise the herbicidal compounds, and to their use for controlling weeds, in particular in crops of useful plants.
US09035048B2 Tetrahydrotriazine compounds for treating diseases associated with AMPK activity
The invention relates to compounds of formula (I) wherein the radicals R1 to R6 have the meaning according to claim 1, and/or physiologically acceptable salts thereof, for the prophylactic or therapeutic treatment and/or monitoring of physiological and/or pathological conditions that are associated with the activity of AMP-activated protein kinase (AMPK). Another object of the invention concerns the use of said compounds for enhancing glucose homeostasis, improving podocytopathy and/or decreasing the production of reactive oxygen species (ROS). The invention also relates to a method for in-vitro diagnosing diabetic nephropathy and a method for screening compounds that reduce podocytopathy, in each case by applying synaptopodin as biomarker.
US09035046B2 Rifaximin derivative and uses thereof
25-desacetyl rifaximin or a pharmaceutically acceptable salt thereof is provided. Methods of treatment of bowl related disorders using isolated and/or purified 25-desacetyl rifaximin or a pharmaceutically acceptable salt thereof are also provided.
US09035039B2 Compositions and methods for silencing SMAD4
The present invention provides compositions comprising therapeutic nucleic acids such as interfering RNA (e.g., dsRNA such as siRNA) that target SMAD4 gene expression, lipid particles comprising one or more (e.g., a cocktail) of the therapeutic nucleic acids, methods of making the lipid particles, and methods of delivering and/or administering the lipid particles (e.g., for treating anemia of inflammation in humans).
US09035037B2 Medical devices
Medical devices comprising an anti-connexin agent suitable for introduction into a subject.
US09035035B2 Macromolecular nucleotide compounds and methods for using the same
The invention describes new structures of the nucleotide conjugates (nuc-macromolecules) comprising at lease one nucleotide moiety coupled to at least one macromolecular compound via a short linker. These conjugates can be used as substrates for various kinds of polymerizing enzymes in the enzymatic synthesis of nucleic acids. In particular, these compounds can be used for labeling nucleic acids.
US09035031B2 Method for providing a β-lactoglobulin product and an α-enriched whey protein isolate
The present invention relates to isolation of whey proteins and the preparation of a whey product and a whey isolate. In particular the present invention relates to the isolation of a β-lactoglobulin product and the isolation of an α-enriched whey protein isolate from whey obtained from an animal. The α-enriched whey protein isolate provided by the present invention is besides from being low in β-lactoglobulin also high in α-lactalbumin and immunoglobulin G.
US09035030B2 Human antibodies that bind the P40 subunit of human IL-12 and methods for using the same
Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, of the invention are useful for detecting hIL-12 and for inhibiting hIL-12 activity, e.g., in a human subject suffering from a disorder in which hIL-12 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies of the invention, and methods of synthesizing the recombinant human antibodies, are also encompassed by the invention.
US09035029B2 CX3CR1-binding polypeptides comprising immunoglobulin single variable domains
The present invention relates to CX3CR1-binding polypeptides, in particular polypeptides comprising specific immunoglobulin domains. The invention also relates to nucleic acids encoding such polypeptides; to methods for preparing such polypeptides; to host cells expressing or capable of expressing such polypeptides; to compositions comprising such polypeptides; and to uses of such polypeptides or such compositions, in particular for prophylactic, therapeutic and diagnostic purposes.
US09035027B2 Dual variable domain immunoglobulins and uses thereof
The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
US09035026B2 Anti-CD16 binding molecules
The present invention relates to binding molecules that specifically bind to the human Fc gamma receptor expressed on the surface of natural killer (NK) cells and macrophages (i.e. FcγRIIIA), and in particular binding molecules that specifically bind the A form FcγRIII but do not bind to the B form of FcγRIII, as well as to the use of such binding molecules in the diagnosis and treatment of disease. The invention further extends to polynucleotides encoding such binding molecules, host cells comprising such polynucleotides and methods of producing binding molecules of the invention using such host cells.
US09035020B1 Insulins with an acyl moiety comprising repeating units of alkylene glycol containing amino acids
Acylated insulins wherein an acyl moiety is attached to the parent insulin and wherein the acyl moiety comprises repeating units of alkylene glycol containing amino acids and wherein there is only one lysine residue (K & Lys) in the parent insulin, having satisfactory properties when administered pulmonary.
US09035019B2 Synthesis of high molecular weight PEO using non-metal initiators
A new synthetic method to prepare high molecular weight poly(ethylene oxide) with a very narrow molecular weight distribution (PDI<1.5) is described. The method involves a metal free initiator system, thus avoiding dangerous, flammable organometallic compounds.
US09035017B2 Method for making poly(hydridocarbyne)
Poly(hydridocarbyne) (PHC) is synthesized by a hybrid, active-metal/electrochemical method by applying a voltage to the electrodes at least one of which is an active-metal, the electrodes being immersed in a trisubstituted halomethane solution. The active-metal electrode and halomethane solution both partake in the electrochemical reaction.
US09035013B2 Sulphur-containing triazine monomer that can be used for the synthesis of a polymer membrane for a fuel cell
A sulphur-containing triazine monomer is provided that can be used in the synthesis of a polymer membrane for a PEM-type fuel cell. The sulphur-containing triazine monomer has a structure corresponding to a formula (I): in which: Tz represents a 1,3,5-triazine nucleus; X1 and X2, which are identical or different, represent S, SO, or SO2; Ar1, Ar2, Ar4 and Ar5, which are identical or different, represent a substituted or unsubstituted phenylene group; Ar3 represents a substituted or unsubstituted phenyl group; and Z1 and Z2, which are identical or different, are selected from a group that includes halogens, hydroxyl, alkoxyl, thiol, carboxyl, carboxylates, amine, sulphonamide, acyl chlorides, sulphonyl chlorides, sulphonyl fluorides, isocyanates, and combinations thereof.
US09035010B2 Organosilicon compounds and their use for producing hydrophilic surfaces
Compounds of the formula where R1 each individually is identical or different and is a hydrocarbon radical, R2 each individually is hydrogen or a methyl radical, n is an integer from 6 to 11, and m is 0 or 1, with the proviso that the sum of the number of carbon atoms in the three radicals R1 in the compound of the formula (I) is 6 to 24, can be admixed with curable polymer compositions to form products with hydrophilic surfaces, or can be applied to surfaces to render them hydrophilic.
US09035007B2 Polyolefin strap comprising a random copolymer of propylene with 1-hexene
A strap comprising a propylene and 1-hexene copolymer containing from 0.3 wt % to less than 5 wt % of 1-hexene derived units said copolymer having a melt flow rate (MFR) determined according to ISO method 1133 (230° C., 2.16 kg ranging from 0.3 to less than 11 g/10 min.
US09035004B2 Semiconducting compounds and devices incorporating same
Disclosed are molecular and polymeric compounds having desirable properties as semiconducting materials. Such compounds can exhibit desirable electronic properties and possess processing advantages including solution-processability and/or good stability.
US09035003B2 High capacity magnetic nanoparticles as supports for reagents and catalysts
A magnetic particle-polymer hybrid material can include: a substance having a structure of Formula 1 or derivative or salt thereof: Z(Y-Triazole-CH2—X—CH2—(FP)n)m (Formula 1), wherein Z is a magnetic particle smaller than 1 mm; n and m are independently integers; Y includes a first linker having an alkyl and/or aryl linked to the magnetic particle; X is CH2 or a heteroatom; FP is a functionalized polymer having: a first structure derived from a first norbornene compound linked to the magnetic particle through the Y-Triazole-CH2—X—CH2 linker; and one or more monomeric units each including a second structure derived from a second norbornene compound, where one of the monomeric units is linked to the first structure through a saturated or unsaturated alkyl, each monomeric unit includes a functional group capable of binding with another substance.
US09034994B2 Systems and methods for real-time catalyst particle size control in a polymerization reactor
Polymerization reactor systems providing real-time control of the average particle size of catalyst system components are disclosed. Methods for operating such polymerization reactor systems also are described.
US09034990B2 Compatibilized polypropylene heterophasic copolymer and polylactic acid blends for injection molding applications
Injection molded articles and process of forming the same are described herein. The processes generally include providing a polyolefin including one or more propylene heterophasic copolymers, the polyolefin having an ethylene content of at least 10 wt. % based on the total weight of the polyolefin; contacting the polyolefin with a polylactic acid and a reactive modifier to form a compatiblized polymeric blend, wherein the reactive modifier is produced by contacting a polypropylene, a multifunctional acrylate comonomer, and an initiator under conditions suitable for the formation of a glycidyl methacrylate grafted polypropylene (PP-g-GMA) having a grafting yield in a range from 1 wt. % to 15 wt. %; and injection molding the compatibilized polymeric blend into an article.
US09034989B2 Branched PHA compositions, methods for their production, and use in applications
Branched PHA compositions, and related methods and articles are disclosed.
US09034986B2 Solvent-free crosslinked polyrotaxane material and process for production of same
A material comprising crosslinked polyrotaxanes which exhibits desired viscoelasticity, particularly stress-strain characteristics with a wide low-stress region, in spite of being free from solvent; and a process for production of the same. The material comprises a first polyrotaxane bearing first cyclic molecules and a second polyrotaxane bearing second cyclic molecules, and the first and second polyrotaxanes are crosslinked via the first and second cyclic molecules. The material is free from solvent and exhibits a stress of 2.0 MPa or below at 50% strain.
US09034983B2 Poly(butylene-co-adipate terephthalate), method of manufacture and uses thereof
A method for preparing poly(butylene terephthalate-co-adipate) copolymer by polymerizing 1,4-butane diol, an adipic acid component and an aromatic dicarboxy compound derived from polyethylene terephthalate, and a polyester component residue in the presence of a catalyst under conditions effective to form poly(butylene terephthalate-co-adipate) oligomers; adding a quencher; and reacting the quenched poly(butylene terephthalate-co-adipate) oligomers with a chain extender.
US09034977B2 Polymer product and the use of the same as dispersing agent
The invention relates to a polymer product obtained by polymerization ofi) at least one monomer selected from N-vinylformamide and vinyl acetate, andii) maleic anhydrideto give a copolymer comprising N-vinylformamide and/or vinyl acetate and maleic anhydride followed by hydrolyzing formamide groups originating from N-vinylformamide to amino groups and/or acetate groups originating from vinyl acetate to hydroxyl groups and acid anhydride to dicarboxylic acid groups to give a water-soluble copolymer comprising amine and/or hydroxyl and carboxyl groups, wherein the molar ratio of the N-vinylformamide and/or vinyl acetate monomer to the maleic anhydride monomer is from 70:30 to 30:70. The polymer product can be used as a dispersing agent or as a scale inhibiting agent.
US09034976B2 Hydrogenated petroleum resin pellet production method
After a cyclopentadiene compound and a vinyl aromatic compound are thermally polymerized, the obtained copolymer is subjected to a hydrogenation reaction to form a hydrogenated product. After most of the hydrogenation solvent is separated by a solvent evaporation tank from the hydrogenated product, an additive separately prepared by dissolving an antioxidant is added to the hydrogenated product to form a mixture. While the hydrogenation solvent is a naphthenic solvent, the additive is prepared by dissolving the antioxidant in an aromatic additive solvent having the same carbon atoms as those of the hydrogenation solvent. Then, the low-molecular-weight component as well as the remaining hydrogenation solution and the additive solvent are separated by a thin-film evaporator from the mixture. The obtained molten resin is pelletized to produce hydrogenated petroleum resin pellets. The time for uniformly blending the antioxidant can be shortened.
US09034975B2 Composite material for structural applications
Composite material that contain epoxy resin which is toughened and strengthened with thermoplastic materials and a blend of insoluble particles. The uncured matrix resins include an epoxy resin component, a soluble thermoplastic component, a curing agent and an insoluble particulate component composed of elastic particles and rigid particles. The uncured resin matrix is combined with a fibrous reinforcement and cured/molded to form composite materials that may be used for structural applications, such as primary structures in aircraft.
US09034973B2 Composition for forming intermediate film for laminated glass, intermediate film for laminated glass and laminated glass
The object of the present invention is to provide an intermediate film for laminated glass which prevents reductions of transparency and appearance property caused by permeation of moisture and water. The above object is attained by the present invention, i.e., a composition for forming an intermediate film for a laminated glass which comprises ethylene-vinyl acetate copolymer and a compound having alkyleneoxy group. The composition of the present invention enables the formation of an intermediate film for a laminated glass that restrains white spots from occurring by the permeation of moisture and water.
US09034970B2 Curable fiberglass binder comprising salt of inorganic acid
Formaldehyde-free binder compositions are described that include an aldehyde or ketone, a nitrogen-containing salt of an inorganic acid, and an acidic compound. The acidic compound may be an organic acid, such as maleic acid or citric acid among others. The acidic compound is supplied in quantities that lower the pH of the binder composition to about 5 or less. The binder compositions may be used in methods of binding fiberglass and the resulting fiberglass products have an improved tensile strength due to the addition of the acidic compound.
US09034969B2 Rubber composition comprising a thiazoline
A rubber composition for the manufacture of tires, based on a blend of at least one diene elastomer chosen from natural rubber and synthetic polyisoprene and of one or more diene elastomers chosen from the group consisting of polybutadienes, butadiene copolymers and isoprene copolymers, on one or more reinforcing fillers and on a vulcanization system, the said vulcanization system comprising one or more thiazoline compounds of formula:
US09034968B2 Cationic polymers for treating construction aggregates
The present invention provides methods, admixture compositions for treating clay-bearing aggregates used for construction purposes, and aggregate compositions for construction purposes. The clay-bearing aggregates are treated with a cationic copolymer made from two and preferably three different monomer components. Cementitious compositions containing the treated aggregates are also described.
US09034967B2 Non-halogenated polyolefin compounds having good processing properties
A non-halogenated flame retardant thermoplastic compound is disclosed. The compound comprises one or more grafted polyolefin resins, non-halogenated flame retardant, non-halogenated processing aid, a compatibilizer, and, optionally, other additives. The non-halogenated processing aid found to be useful, among several candidates, was a dendritic polymer.
US09034966B2 Flame retardant polycarbonate compositions
The present invention relates to impact-modified polylactic acid/polycarbonate compositions, containing A) 48 to 90 parts by weight, based in each case on the sum of the parts by weight of components A+B+C+D, of aromatic polycarbonate, B) 1 to 40 parts by weight, based in each case on the sum of the parts by weight of components A+B+C+D, of polylactic acid, C) 0.5 to 15 parts by weight, based in each case on the sum of the parts by weight of components A+B+C+D, of graft polymer, D) 2 to 25 parts by weight, based in each case on the sum of the parts by weight of components A+B+C+D, of a salt of a phosphinic acid and optionally additional components such as vinyl polymers and additives, which are distinguished by an optimum combination of high heat resistance, good flame retardance and excellent mechanical properties, to the use of the polycarbonate compositions for the production of mouldings and the mouldings themselves.
US09034964B2 Waterborne coating compositions containing low-VOC coalescents that are hydroxypivalyl hydroxypivalate esters
Waterborne coating compositions are disclosed that include a latex emulsion polymer, and, as a coalescent, a diester of hydroxypivalyl hydroxypivalate. The coating compositions of the invention have a reduced VOC content and provide satisfactory coalescing activity.
US09034963B2 Transparent thermoplastic resin composition having improved whitening resistance at low temperature and excellent impact strength
A transparent thermoplastic resin composition includes (A) a rubber-modified graft copolymer which is prepared by copolymerizing (a2) a (meth)acrylic acid alkyl ester monomer, (a3) a styrene-based monomer and (a4) an acrylonitrile-based monomer onto (a1) a butadiene-based rubber polymer; (B) a styrene-based copolymer having a glass transition temperature of about 90 to about 100° C. which is prepared by copolymerizing (b1) a methacrylic acid alkyl ester monomer, (b2) an acrylic acid alkyl ester monomer, (b3) a styrene-based monomer and (b4) an acrylonitrile-based monomer; and (C) a silicone oil. The composition can have improved whitening resistance at low temperatures and/or excellent impact strength.
US09034961B2 Rubber composition and tire using the same
In order to provide a rubber composition in which dispersibility of silica is improved and in which a viscosity of an unvulcanized rubber is lowered and a heat build-up improving effect of a vulcanized rubber is well exerted, and a tire prepared by using the rubber composition, the rubber composition is endowed with a constitution in which 100 parts by mass of at least one rubber component selected from natural rubber and/or diene base synthetic rubbers are compounded with 55 to 200 parts by mass of silica and 0.5 to 15 parts by mass of at least one of alkanolamines represented by the following Formula (I): [in Formula (I), R1 represents an alkyl group or an alkenyl group having 1 to 24 carbon atoms, and the above alkyl group and alkenyl group may be any of a linear group, a branched group and a cyclic group; m and n represent an average addition molar number, and m and n are numerical values which represent m+n=1 to 20].
US09034960B2 Antidrift composition
A solid, water-soluble fast-dissolving antidrift composition includes a urea-based complex-forming component (i) complexed with an antidrift component (ii), the antidrift composition optionally further including an adjuvant component (iii).
US09034957B2 High-flow hollow-fiber membranes containing polymer blends
A composition for making polymeric fiber membranes, for use in non-cryogenic separation of gases, substantially improves product flow, with only a small decrease in the recovery ratio. The composition is a spin dope including tetrabromo bis-phenol A polycarbonate (TBBA-PC) and tetrabromo bishydroxyphenylfluorene polycarbonate (TBBHPF-PC), in proportions, by weight, ranging (in percent) from about 60/40 to 40/60, and n-methyl pyrrolidinone (NMP) and triethylene glycol (TEG), wherein the ratio of the amounts of NMP to TEG, by weight, is in the range of about 1.6-2.5. The spin dope is used to make hollow fibers for use in gas-separation membrane modules.
US09034952B2 Reduced salt precipitation in carbohydrate containing binder compositions
Aqueous binder compositions with reduced rates of salt precipitation are described. The compositions may include a carbohydrate and a sequestrant for sequestering one or more multivalent ions (e.g., Ca2+, Mg2+, Ba2+, Al3+, Fe2+, Fe3+, etc.). The sequestrant reduces a precipitation rate for the multivalent ions from the aqueous binder composition. Methods of reducing salt precipitation from a binder composition are also described. The methods may include the steps of providing an aqueous binder solution having one or more carbohydrates. They may also include adding a sequestrant for one or more multivalent ions to the aqueous binder solution. The sequestrant reduces a precipitation rate for the multivalent ions from the binder composition.
US09034951B2 Imitation wood
An imitation wood composition or a composition for making imitation wood, comprising a mixture of 30-40 wt % PVC resin and 30-40 wt % rice-husk and/or peanut-shell powder having a particle size of 0.42-0.25 mm (40-60 mesh). Further disclosed is an imitation wood produced by extruding the imitation wood composition or the composition for making imitation wood. The imitation wood exhibits an appearance and feel very similar to natural wood and can be processed using conventional wood tools. The imitation wood can be painted and adhesively bonded without problems and is suitable for outdoor applications, in particular in humid or wet environments, because of the very high weathering resistance thereof.
US09034950B2 Rubber composition and pneumatic tire
The purpose of the present invention is to provide a rubber composition with which it is possible to produce a tire that retains wear resistance and has excellent frictional force on ice, and a pneumatic tire using the rubber composition. The rubber composition of the present invention is a rubber composition comprising a diene rubber, carbon black and/or a white filler, and a master batch prepared by premixing a non-diene rubber and an organic peroxide, wherein a total content of carbon black and white filler is from 20 to 70 parts by mass per 100 parts by mass of diene rubber and a content of the non-diene rubber in the master batch is from 3 to 30 parts by mass per 100 parts by mass of the diene rubber.
US09034949B2 Method for producing flame-proofed thermoplastic molding compounds
The invention relates to a method for producing thermoplastic molding compounds, comprising: A) 40 to 99 wt % of at least one thermoplastic polymer, B) 1 to 60 wt % of a flame-proofing agent component containing an expandable graphite, and C) 0 to 60 wt % of further additives, by melt-mixing components A), B) and C) in a screw-type extruder, wherein the screw-type extruder, along the feed direction, comprises, in the following order, at least one dosing zone, a plastifying zone, a homogenizing zone, a second dosing zone, and a discharge zone, in that the dosing takes place into the screw-type extruder having the length L, wherein the length L is defined as the section starting with the first dosing unit for adding components A, B and/or C and ending, in the feed direction, at the discharge opening, a melt is generated after adding components A, B and C in the range of 0 liter to 0.15 liter in a first method step in the presence of component B1), and in a second method step, after the addition of component B1) in the range of 0.5 liter to 0.95 liter, component B1) is mixed into said melt, wherein said method offers technical advantages.
US09034948B2 Additive process for production of dimensionally stable three dimensional objects
Generally, compositions and methods of producing dimensionally stable three dimensional objects using an additive build up process. Specifically, materials combinable in an additive build up process using a materials printer for the production of stable three dimensional molds useful in the production of molded or formed parts.
US09034942B2 Polymer material, ophthalmic lens and contact lens
Provided is a polymer material having superior water wettability and lubricity, and enabling persistence of the same by allowing the surfactant to be retained by the polymer material so as not to be gradually released. The present invention is directed to a polymer material including:[I] a polymer having a constitutional unit derived from (A) a polymerizable compound having an acryloyloxy group and not having a silicon atom; and [II] a surfactant. The content of the surfactant [II] is preferably 0.05% by mass or greater and 1% by mass or less. The surfactant [II] is preferably a nonionic surfactant having a polyoxyethylene group.
US09034941B2 Hydrophilic gels from polyurethane-based photoinitiators
The present invention relates to the use of polymeric photoinitiators based on polyalkyletherurethane backbones in the production of hydrophilic gels, in particular hydrogels. The invention relates to methods for manufacturing hydrophilic gels using said polymeric photoinitiators, and the hydrophilic gels thus obtained.
US09034934B1 Polythylene aerogels and method of their production
A method for making polyethylene aerogels, including high molecular weight aerogels, commences by in a hydrocarbon solvent (e.g., toluene or benzene) in which polyethylene is insoluble at room temperature, adding polyethylene to the solvent heated to a temperature at which said polyethylene is soluble to form a reaction mixture. A free-radical catalyst is added to the reaction mixture and the reaction mixture is held until the desired gelation of the polyethylene has been achieved. The reaction mixture is cooled to about room temperature; and the hydrocarbon solvent is replaced with a gas (e.g., CO2 or air) to form the polyethylene aerogel. Optionally, the cooled reaction mixture can be contacted with an anti-solvent for polyethylene to replace the hydrocarbon solvent with the anti-solvent. Silica aerogel particles can be encapsulated in polyethylene aerogel by adding the particles to the polyethylene gelation reaction mixture.
US09034932B1 Zwitterionic-bias material for blood cell selection
The invention provides a zwitterionic-bias material for blood cell selection, being a copolymer formed by zwitterionic structural units and charged structural units wherein the zwitterionic structural unit comprises at least one positively charged moiety and one negatively charged moiety, a distance between the positively charged moiety and the negatively charged moiety is a length of 1˜5 carbon-carbon bonds, and the zwitterionic structural units and charged structural units are randomly arranged to have zwitterionic-bias.
US09034928B2 Methods for metabolic imaging
The present embodiments disclose the preparation of hyperpolarized 13C dialkyl succinate compounds and hyperpolarized 13C dialkyl fumarate compounds and their use in real time, in vivo metabolic imaging of the TCA cycle.
US09034926B2 Topical nitrone spin trap compositions for psoriasis
Psoriasis is treated by application of a composition containing a nitrone spin trap such as α-phenyl t-butyl nitrone (PBN) and derivatives thereof. Preferred compositions and method of treatments further comprise at least one adjunctive ingredient including fatty acid esters of ascorbic acid such as ascorbyl palmitate and ascorbyl stearate, and polyenylphosphatidylcholine.
US09034924B2 N-acyl basic amino acid dispersion
Provision of an N-acyl basic amino acid dispersion superior in dispersibility. The present invention provides a production method of an N-acyl basic amino acid dispersion having a pH of 2 to 12, comprising (1) a step of dissolving an N-acyl basic amino acid in a base solution, and (2) a step of mixing the obtained N-acyl basic amino acid solution with one or more equivalents of an acid relative to the base.
US09034919B2 Bioactive-rich concentrates and nutritive and therapeutic products containing same
This invention relates generally to the field of compositions for use as nutraceuticals, food additives or adjuncts to conventional drug therapies. In particular, the invention relates to compositions derived from natural oil sources which can be used for effective and inexpensive treatment of cardiovascular diseases, hypercholesterolemia, diabetes, cerebrovascular disease, neurological disorders, or liver abnormalities.
US09034914B2 Pharmaceutical composition comprising rotigotine salts (acid or Na), especially for iontophoresis
The present invention relates to new salts of 6-(propyl-(2-thiophen-2-ylethyl)amino)tetralin-1-ol(rotigotine), their use as a medicament, for example for the treatment of CNS disorders like Parkinson Disease, RLS, fibromyalgia and/or depression, in particular through electromotive administration. The present invention relates to pharmaceutical formulations suitable for iontophoresis that provide enhanced iontophoretic delivery of rotigotine to at least one target tissue. The formulations are further characterized by good to excellent solubility of the salts in aqueous solutions.
US09034913B2 Process for annealing amorphous atorvastatin
Processes for annealing amorphous atorvastatin is described. Pharmaceutical compositions and formulations containing annealed amorphous atorvastatin are also described.
US09034911B2 Composition of a 5-HT2A serotonin receptor modulator useful for the treatment of disorders related thereto
The present invention relates to certain compositions of a 5-HT2A serotonin receptor modulator and methods for their preparation. The compositions disclosed herein are useful for increasing slow wave sleep, improving sleep consolidation, improving sleep maintenance and improving sleep quality, and for treating insomnia and related sleep disorders, dyssomnias, parasomnias and nonrestorative sleep and the like. The compositions disclosed herein are further useful for treating platelet aggregation, coronary artery disease, myocardial infarction, transient ischemic attack, angina, stroke, atrial fibrillation, thrombosis, asthma or symptoms thereof, agitation or symptoms thereof, behavioral disorders, drug induced psychosis, excitative psychosis, Gilles de la Tourette's syndrome, manic disorder, organic or NOS psychosis, psychotic disorders, psychosis, acute schizophrenia, chronic schizophrenia, NOS schizophrenia and related disorders, diabetic-related disorders and progressive multifocal leukoencephalopathy and the like.
US09034910B2 Methods of treating alpha adrenergic mediated conditions
Described herein are compounds for and methods of treating conditions or diseases in a subject by administering to the subject a pharmaceutical composition containing an effective amount of an α-adrenergic modulator. The compounds and methods are also useful for alleviating types of pain, acute, neuropathic and chronic.
US09034907B2 Inhibitors of glutaminyl cyclase
Compounds of formula (I), combinations and uses thereof for disease therapy, or a pharmaceutically acceptable salt, solvate or polymorph thereof, including all tautomers and stereoisomers thereof wherein: R1 represents and R2, R3, R4, R5, R6, X1, X2, X3, X4, Y and Z are as defined throughout the description and the claims.
US09034902B2 Methods for treatment of attention deficit hyperactivity disorder
Therapeutic compositions and methods for treatment of attention deficit disorder (ADD) or attention deficit hyperactivity disorder (ADHD) include dosage forms that deliver a therapeutic amount of active drug in a delayed and controlled release formulation. The dosage form can be administered at night and drug release is delayed for from 4 to 6 hours or longer, followed by an ascending release rate.
US09034901B2 Pitavastatin calcium and process for its preparation
The invention provides the process for the preparation of pitavastatin and its pharmaceutically acceptable salts thereof. In particular, the invention provides a process for the preparation of stable pitavastatin calcium in crystalline form having water content less than 5% wt/wt. The present invention also provides stable crystalline form of pitavastatin calcium substantially free from crystal Form-A and use thereof for pharmaceutical compositions.
US09034896B2 N-(imidazolidin-2-ylidene)-heterocyclopenta[b]pyridine derivatives as modulators of alpha 2 adrenergic receptors
The present invention relates to novel N-(imidazolidin-2-ylidene) Heterocyclopenta[b]pyridine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
US09034895B2 Composition and methods for treating glioblastoma
The disclosure provides methods of treating glioblastoma, methods of screening for compounds that treat glioblastoma, and pharmaceutical compositions useful the treatment of glioblastoma.
US09034894B2 Derivate, preparation method and use of 10-methoxycamptothecin
Provided is a 10-methoxycamptothecine derivate of formula (1), wherein R is selected from hydrogen, C1-6 alkyl, C1-6 haloalkyl, aryl substituted C1-6 alkyl, phosphate substituted C1-6 alkyl, amino-substituted C1-6 alkyl, carboxyl substituted C1-6 alkyl, hydroxyl substituted C1-6 alkyl, and amide-substituted C1-6 alkyl; R1 is selected from hydrogen and t-butoxycarbonyl substituted amino. Also provided in the present invention are the preparation method of the derivate and the use thereof in anti-tumor drug preparation.
US09034890B2 Combined acetylcholinesterase inhibitor and quaternary ammonium antimuscarinic therapy to alter progression of cognitive diseases
A method administers quaternary ammonium anti-cholinergic muscarinic receptor antagonists in combination with acetyl-cholinesterase inhibitors to treat either cognitive impairment or acute delirium. This therapy results in a modification of a cognitive disorder or disease, namely a slow down in the disease progression. In one preferred embodiment, the disease is dementia with Lewy Bodies. New formulations for quaternary ammonium anti-cholinergic muscarinic receptor antagonists are also disclosed.
US09034888B2 Substituted 2-imidazolidones and analogs
Compounds of formula (I): wherein R1, R2, R3, R4, R7, R6, R7, R8, R9, A, X and Y as defined herein are provided as useful for the treatment of cancer or for the manufacture of anti-cancer agents.
US09034886B2 4-aminoquinazoline derivatives and uses thereof
The present invention provides a 4-aminoquinazoline derivative having the chemical structure of the following formula, and the use thereof. It is demonstrated by the pharmacological experiment that, the compound or a salt thereof according to the present invention not only has distinct inhibitory effect on histone deacetylases, but also has stronger differentiation induction and anti-proliferative activities for certain tumor cells. It can be used in the treatment of cancers and diseases related to cell differentiation and proliferation. Excellent efficacy is observed especially for leukemia and a solid tumor. As demonstrated by the animal test, the compound or a salt thereof according to the present invention is less toxic.
US09034884B2 Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as JAK inhibitors
The present invention provides heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines of Formula I: wherein X, Y, Z, L, A, R5, n, m, and r are defined above, as well as their compositions and methods of use, that modulate the activity of Janus kinases (JAKs) and are useful in the treatment of diseases related to the activity of JAKs including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.
US09034883B2 Vasoprotective and cardioprotective antidiabetic therapy
The present invention relates to certain DPP-4 inhibitors for treating and/or preventing oxidative stress, vascular stress and/or endothelial dysfunction as well as to the use of such DPP-4 inhibitors in treatment and/or prevention of diabetic or non-diabetic patients, including patient groups at risk of cardiovascular and/or renal disease.
US09034881B2 Treatment for vitiligo
Compounds I and II, as well as prodrugs, hydrates, solvates, N-oxides, salts and pharmaceutical compositions containing them, are useful for treating vitiligo. In certain embodiments, the compounds are provided in topical compositions.
US09034878B2 Treatment of diseases
The invention provides (i) a method of treating metabolic syndrome in an animal, (ii) a method of suppressing the appetite of an animal, (iii) a method of treating obesity in an animal, (iv) a method of reducing the weight of an animal in need thereof, (v) a method of reducing a blood lipid level in an animal in need thereof, (vi) a method of treating non-alcoholic steatohepatitis in an animal, and (vii) a method of inhibiting adipogenesis. The methods comprise administering an effective amount of an active ingredient, wherein the active ingredient comprises a diketopiperazine, a prodrug of a diketopiperazine or a pharmaceutically-acceptable salt of either of them to the animal. The invention also provides a kit comprising a container holding a diketopiperazine, a prodrug of a diketopiperazine or a pharmaceutically-acceptable salt of either of them; and instructions for administration. The diketopiperazines have the formula given in the application.
US09034877B2 Bifunctional/polyfunctional dopamine D2/D3 agonist as neuroprotective agents for treatment of neurodegenerative diseases
A precursor for the deposition of a thin film by atomic layer deposition is provided. The compound has the formula MxLy where M is a metal and L is an amidrazone-derived ligand or an amidate-derived ligand. A process of forming a thin film using the precursors is also provided.
US09034874B2 Carbamate/urea derivatives
The invention relates to compound of the formula I or a salt thereof, wherein the substituents are as defined in the specification; to its preparation, to its use as medicament and to medicaments comprising it.
US09034873B2 Pyridazine and pyrrole compounds, processes for obtaining them and uses
The present disclosure describes compounds of the following formula in which: the groups A, which may be identical or different, represent a group n is an integer equal to 1 or 2, Y represents an oxygen or sulfur atom, a methylene, hydroxymethylene, carbonyl or thiocarbonyl group, or a group of formula the groups R, which may be identical or different, represent a hydrogen, an alkyl, alkylamine, hydroxyl-alkyl or alkyloxy chain containing from 1 to 6 carbons, or a —COOH, —CONH2, —COOR2 or —CONHR2 group in which R2 is an alkyl chain containing from 1 to 6 carbons, or, when the substituents R are identical in the 2-pyridinyl groups, the substituents R2 may together form an ethereal cyclic alkyl chain, with the exception of the compounds: 2,6-di[5-(2-pyridyl)pyrrol-2-yl]pyridine and bis[5-(6-methyl-2-pyridyl)pyrrol-2-yl]methane.
US09034869B2 Bridged heterocyclic compounds and methods of use
This disclosure relates to new compounds that may be used to modulate a histamine receptor in an individual. Novel compounds are described, including new bridged heterocyclic[4,3-b]indole compounds. Pharmaceutical compositions are also provided. Pharmaceutical compositions comprising the compounds are also provided, as are methods of using the compounds in a variety of therapeutic applications, including the treatment of a cognitive disorder, psychotic disorder, neurotransmitter-mediated disorder and/or a neuronal disorder.
US09034865B2 Pyrido [4,3-B] indole and pyrido [3,4-B] indole derivatives and methods of use
This disclosure is directed to pyrido[4,3-b]indole and pyrido[3,4-b]indole derivatives. Pharmaceutical compositions comprising the compounds are also provided, as are methods of using the compounds in a variety of therapeutic applications, including the treatment of a cognitive disorder, psychotic disorder, neurotransmitter-mediated disorder and/or a neuronal disorder.
US09034864B2 Azetidinyloxyphenylpyrrolidine compounds
The invention provides certain azetidinyloxyphenylpyrrolidine compounds, particularly compounds of formula I wherein R is hydrogen or methyl, and pharmaceutical compositions thereof. The invention further provides methods of using a compound of formula I to treat overactive bladder.
US09034863B2 Compositions and methods for inhibiting entry of a hepatic virus
The present invention embraces Niemann-Pick C1-like 1 protein antagonists and agents that inhibit hepatic virus infection for use in the prevention and treatment of a hepatic virus infection.
US09034862B2 Compositions and methods for the treatment of cancer
The present invention relates to compositions, kits, and methods for treatment of cancers. In some cases, the composition comprises a platinum compound comprising a phenanthridine ligand.
US09034852B2 Substituted phenoxy N-alkylated thiazolidinediones as estrogen related receptor-α modulators
The present invention relates to compounds of Formula (I), methods for preparing these compounds, compositions, intermediates and derivatives thereof and for treating a condition including but not limited to ankylosing spondylitis, artherosclerosis, arthritis (such as rheumatoid arthritis, infectious arthritis, childhood arthritis, psoriatic arthritis, reactive arthritis), bone-related diseases (including those related to bone formation), breast cancer (including those unresponsive to anti-estrogen therapy), cardiovascular disorders, cartilage-related disease (such as cartilage injury/loss, cartilage degeneration, and those related to cartilage formation), chondrodysplasia, chondrosarcoma, chronic back injury, chronic bronchitis, chronic inflammatory airway disease, chronic obstructive pulmonary disease, diabetes, disorders of energy homeostasis, gout, pseudogout, lipid disorders, metabolic syndrome, multiple myeloma, obesity, osteoarthritis, osteogenesis imperfecta, osteolytic bone metastasis, osteomalacia, osteoporosis, Paget's disease, periodontal disease, polymyalgia rheumatica, Reiter's syndrome, repetitive stress injury, hyperglycemia, elevated blood glucose level, and insulin resistance.
US09034849B2 Fatty acid amide hydrolase inhibitors
The present invention provides fatty acid amide hydrolase inhibitors, solid forms thereof, compositions thereof, and methods of making and using the same.
US09034847B2 Inhibiting inflammation with milk oligosaccharides
A method of inhibiting inflammation in a subject comprising the administration of milk oligosaccharides or glycoconjugates containing milk oligosaccharides is disclosed.
US09034844B2 6′-sialyllactose salts and process for their synthesis and for the synthesis of other alpha-sialyloligosaccharides
The present invention relates to a process of synthesis of α-sialyl oligosaccharides and in particular of 6′-sialyllactose and its salts comprising a step of coupling by Koenigs-Knorr reaction under conditions that allow its use on an industrial scale.
US09034843B2 Ophthalmic composition
The present invention provides an ophthalmic composition which stabilizes the tear film during wearing contact lens, prevents eye dryness, imparts a favorable sensation in using, is highly convenient with no risk of misuse and shows a high efficiency in the course from manufacturing to sales. More specifically, the present invention provides a wetting solution—eye drops for contact lenses comprising (A) one or more member(s) selected from the group consisting of a cellulose-based polymer, a vinyl-based polymer, polyethylene glycol and dextran; and (B) one or more member(s) selected from the group consisting of chondroitin sulfate, alginic acid and salts thereof; and (C) a nonionic surfactant.
US09034838B2 miR-31 in duchenne muscular dystrophy therapy
The invention relates to the therapy of Duchenne Muscular Dystrophy (DMD) by means of modulating the amount of a specific miRNA (miR-31).
US09034836B2 Gene therapy for amyotrophic lateral sclerosis and other spinal cord disorders
This disclosure provides methods and compositions for treating disorders or injuries that affect motor function and control in a subject. In one aspect, the invention a transgene product is delivered to a subject's spinal cord by administering a recombinant neurotrophic viral vector containing the transgene to the brain. The viral vector delivers the transgene to a region of the brain which is susceptible to infection by the virus and which expresses the encoded recombinant viral gene product. Also provided are compositions for delivery of a transgene product to a subject's spinal cord by administering a recombinant neurotrophic viral vector containing the transgene to the subject's brain.
US09034834B2 Antiviral supplement formulations
The disclosure provides an oral antiviral supplement composition comprising a lysine, an ascorbic compound, a flavonoid glycoside, a threonine, and a pyridoxine. The disclosure also provides a method of reducing viral replication in a cell comprising treating a virus-infected cell with a composition of the disclosure. The disclosure further provides a method for the treatment and prophylaxis of a viral infection in a patient comprising administering a composition of the disclosure.
US09034827B2 Syndecan peptides and polypeptides as inhibitors of cancer
The invention provides for peptides from syndecan 1 and methods of use therefor. These peptides can inhibit α4β6 interaction with HER2, thereby preventing tumor cell growth and tissue invasion.
US09034826B2 Use of epidermal growth factor for the morphofunctional restoration of peripheral nerves in diabetic neuropathy
The present invention is relevant to human medicine, and, in particular, to the use of Epidermal Growth Factor (EGF) in a pharmaceutical composition, said composition is administered through infiltration at the periphery of nerve trunks and/or ganglia, for the morphofunctional restoration of peripheral nerves in painful, sensory-motor neuropathy, as well as ischemic neuritis. It is also relevant to an EGF containing composition, where this molecule can be formulated together with anesthetic or analgesic drugs, or encapsulated in microspheres, and their use for the morphofunctional restoration of peripheral nerves in painful, sensory-motor neuropathy, as well as in ischemic neuritis.
US09034825B2 Treatment of myocardial injury with humanin analogs
Provided are methods of using humanin and humanin analogs to treat a mammal exhibiting or at risk for insulin resistance, increase insulin sensitivity in a mammal exhibiting or at risk for insulin resistance, treat type-2 diabetes mellitus, metabolic syndrome, and neurodegeneration, treat and prevent myocardial injury, and determine longevity.
US09034824B2 Antioxidant, anti-inflammatory, anti-radiation, metal chelating compounds and uses thereof
Potent compounds having combined antioxidant, anti-inflammatory, anti-radiation and metal chelating properties are described. Short peptides having these properties, and methods and uses of such short peptides in clinical and cosmetic applications are described.
US09034822B2 Methods of using antibodies during anticoagulant therapy of dabigatran and/or related compounds
The present invention relates to antibody molecules against anticoagulants, in particular dabigatran, and their use as antidotes of such anticoagulants.
US09034819B2 Method of lowering cholesterol and triglycerides by administering exendins
Provided herein are pharmaceutical formulations containing exendins, exendin agonists, or exendin analog agonists that are administered at therapeutic plasma concentration levels over a sustained period of time to lower total cholesterol levels; to lower LDL-cholesterol levels; to lower triglyceride levels; to treat dyslipidemia; to treat and slow the progression of atherosclerosis; and to treat, prevent, and reduce the risk of heart attacks and strokes in patients. In the pharmaceutical formulations and methods of the invention, the exendin may be exendin-4, an exendin-4 agonist, or an exendin-4 analog agonist. The pharmaceutical formulations may be polymer-based pharmaceutical formulations that may be administered once weekly. An exemplary pharmaceutical formulation comprises 5% (w/w) of exenatide, about 2% (w/w) of sucrose, and about 93% (w/w) of a poly(lactide-co-glycolide) polymer, wherein the poly(lactide-co-glycolide) polymer is in the form of microspheres encapsulating the exenatide.
US09034818B2 Pharmaceutical formulations comprising an insulin derivative
The invention concerns a soluble pharmaceutical formulation comprising an insulin derivative wherein the formulation further comprises more than 4 zinc atoms per 6 molecules of the insulin derivative, and a citric acid monohydrate and/or a histidine compound used in an amount sufficient to increase the tendency of the insulin derivative to self-associate into dodecamers. The invention further comprises a process for preparing the soluble pharmaceutical formulation.
US09034815B2 Polypeptide for treating or preventing adhesions
The described invention provides compositions and methods for treating or preventing adhesions in a subject in need thereof, the method comprising the step of (a) administering an adhesion-reducing amount of a composition comprising a polypeptide having the amino acid sequence YARAAARQARAKALARQLGVAA [SEQ ID NO: 1] or a functional equivalent thereof and a carrier. The methods are clinically useful for reducing formation of adhesions initially and for therapeutic treatment of existing scars.
US09034812B2 Compositions and methods for treating biofilms
Compositions and methods for treating biofilm formation and growth on a substrate are provided. The composition comprises 1 ppb to 1,000 ppm of at least one D-amino acid and 1 ppm to 60,000 ppm of at least one biocide. The method comprises contacting the substrate with 1 ppb to 1,000 ppm of at least one D-amino acid and 1 ppm to 60,000 ppm of at least one biocide. The compositions and methods are effective for preventing, reducing or eliminating biofilm formation or biofilm growth or both, as well as eradicating established, recalcitrant biofilms, particularly biofilms comprising sulfate reducing bacteria that are known to cause microbiologically influenced corrosion, biofouling, or both.
US09034807B2 Spacer fluid additive
A spacer fluid comprises a fluid and a viscosity agent. The viscosity agent is a mixture of at least two polyvinylalcohol compositions. A first polyvinylalcohol composition comprises polyvinylalcohols having a first degree of hydrolysis and a second polyvinylalcohol composition comprises polyvinylalcohols having a second degree of hydrolysis. The first and second degrees of hydrolysis are substantially different such that the rheology of the spacer fluid is stable during temperatures changes.
US09034805B2 Fluid treatment systems, compositions and methods for metal ion stabilization in aqueous solutions
Fluid treatment systems and compositions are provided including (a) at least one material including (1) at least one carboxylic acid functional group and (2) at least one sulfur-containing group selected from the group consisting of sulfonyl functional groups, sulfonate functional groups and mixtures thereof; and (b) at least one scale control agent. The fluid treatment systems and compositions can be used to treat aqueous systems, for example as fracturing fluids for treating aqueous compositions found in subterranean formations. Methods for inhibiting formation and/or precipitation of calcium salts in an aqueous composition using the fluid treatment systems or compositions also are provided.
US09034804B2 Fluid treatment systems, compositions and methods for metal ion stabilization in aqueous solutions and/or enhanced fluid performance
Fluid treatment systems and compositions are provided including (a) at least one material including (1) at least one carboxylic acid functional group and (2) at least one sulfur-containing group selected from the group consisting of sulfonyl functional groups, sulfonate functional groups and mixtures thereof; and (b) at least one friction reducing agent selected from the group consisting of guar gums, polyacrylamides, hydratable cellulosic materials, viscoelastic surfactants, and mixtures thereof. The fluid treatment systems and compositions can be used to treat aqueous systems, for example as fracturing fluids for use in fracturing subterranean formations. Methods for inhibiting formation and/or precipitation of metal oxides in an aqueous composition using the fluid treatment systems or compositions also are provided.
US09034803B2 Fluids comprising chitosan crosslinked by titanate
The current application discloses fluids and methods for treating a subterranean formation penetrated by a wellbore. In one aspect, there is provided a fluid comprising chitosan and titanate, where the fluid has an increased viscosity compared with a solution containing chitosan without titanate. In another aspect, there is provided a method of using such fluid to treat a subterranean formation penetrated by a wellbore. The method may comprise mixing chitosan and titanate in a carrying medium, forming a gel comprising chitosan and titanate, introducing the gel into a subterranean formation, and treating the subterranean formation with the gel.
US09034802B2 Friction reduction fluids
The invention provides an oilfield suspending friction reducer treatment composition fluid comprising from about 0.001 weight percent to about 0.5 weight percent of a drag reducing surfactant; at least one drag reducing enhancer selected from the group consisting of polymeric drag reduction enhancers, monomeric drag reduction enhancers, and mixtures thereof.
US09034801B2 Clay inhibitors for the drilling industry
The hydration of clays in drilling operations can be inhibited by employing an aqueous based drilling fluid containing from about 0.2 to about 5 wt % of a hydration inhibitor that comprises bis-hexamethylene-triamine, bis-hexamethylene-triamine salts, or mixtures thereof.
US09034800B2 Fluid loss additives and methods of making and using same
A non-aqueous wellbore servicing fluid comprising a fluid loss additive wherein the fluid loss additive comprises the reaction product of (i) a functional polymer and (ii) an oligomerized fatty acid. A method of conducting an oil-field operation comprising placing a non-aqueous wellbore servicing fluid downhole wherein the non-aqueous wellbore servicing fluid comprises a fluid loss additive comprising the reaction product of (i) a functional polymer and (ii) an oligomerized fatty acid.
US09034799B2 Thermoset nanocomposite particles, processing for their production, and their use in oil and natural gas drilling applications
Use of two different methods, either each by itself or in combination, to enhance the stiffness, strength, maximum possible use temperature, and environmental resistance of thermoset polymer particles is disclosed. One method is the application of post-polymerization process steps (and especially heat treatment) to advance the curing reaction and to thus obtain a more densely crosslinked polymer network. The other method is the incorporation of nanofillers, resulting in a heterogeneous “nanocomposite” morphology. Nanofiller incorporation and post-polymerization heat treatment can also be combined to obtain the benefits of both methods simultaneously. The present invention relates to the development of thermoset nanocomposite particles. Optional further improvement of the heat resistance and environmental resistance of said particles via post-polymerization heat treatment; processes for the manufacture of said particles; and use of said particles in the construction, drilling, completion and/or fracture stimulation of oil and natural gas wells are described.
US09034797B2 Array printing
The invention provides a method of printing, onto a substrate (12), an array (14) of spots of reagent compositions for use in a chemical and/or biochemical analysis. The method includes displacing an array of reagent composition containing capillary tubes (22) arranged alongside one another from an inoperative position to an operative position in which open ends of the capillary tubes (22) simultaneously impinge against a substrate and thereafter displacing the array of tubes (22) from the operative position back to the inoperative position. The invention extends to a printing apparatus (10), a method of printing a layered array of spots of reagent compositions, a method of introducing reagent compositions into the tubes, a reagent introducing device for introducing reagent compositions into the tubes and a printing installation which includes the printing apparatus (10) and the reagent introducing device.
US09034796B2 Method for analysis using nucleic acid microarray
An analytical method aided with a nucleic acid microarray, the nucleic acid microarray having a spot (X 1) onto which a first probe nucleic acid is immobilized, the method includes: allowing a labeled sample nucleic acid (A 1) of a sample to be tested to hybridize with the first probe nucleic acid; providing the spot (X 1) with a labeled verification nucleic acid (B) that has a sequence capable of hybridizing with at least a part of the first probe nucleic acid and is labeled with a label different from the labeled sample nucleic acid (A 1), and allowing the labeled verification nucleic acid (B) to hybridize with at least the first probe nucleic acid at all spots; measuring a labeled quantity value (F 1) of the labeled sample nucleic acid (A 1); and measuring a labeled quantity value (Fc 1) of the labeled verification nucleic acid (B).
US09034794B2 Method for post-emergence crabgrass control
The present invention provides a method for post-emergence selective crabgrass control by applying a composition comprising a first herbicide and a second herbicide in which the first herbicide is 2,4-dinitro-N3,N3-dipropyl-6-(trifluoromethyl)-1,3-benzenediamine and the second herbicide is N-[2,4-dichloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]phenyl]methanesulfonamide to a locus where one to two leaf growth stage crabgrass is present.
US09034792B2 Antifungal compositions
The present invention relates to new antifungal compositions and their use in the treatment of agricultural products.
US09034791B2 Method for controlling noxious organisms
To provide a method which exerts excellent controlling effects on noxious organisms in a field of soybean, corn or cotton.A method for controlling noxious organisms in a field of soybean, corn or cotton, wherein at least one PPO inhibitor compound selected from the group consisting of flumioxazin, sulfentrazone, saflufenacil, oxyfluorfen, fomesafen-sodium, and a compound represented by formula (I): is applied to the field before, at or after sowing a soybean, corn or cotton seed treated with fludioxonil.
US09034790B2 Thermally-responsive record material
The invention describes a thermally-responsive record material substantially free of aromatic isocyanate. The record material comprises a support having provided thereon a heat-sensitive composition comprising a substantially colorless dye precursor comprising a fluoran; and a developer material selected from the group consisting of 4,4′-diaminodiphenylsulfone and 3,3′-diaminodiphenylsulfone, which upon being heated react with said dye precursor to develop color, and including a binder material. Optionally, a modifier compound is included in the heat-sensitive composition. The modifier compound can be selected from the group consisting of a fatty acid amide, preferably a saturated fatty acid amide such as an alkyl amide, a bis methylene alkyl amide, or a bis ethylene alkyl amide, or any of 1,2-diphenoxy ethane, dimethyl diphenoxy ethane, and dimethyl phthalate.
US09034788B2 Filter material comprising porous organic polymers
The invention relates to a unit which comprises a multitude of particles based on porous organic polymers, wherein the organic polymers are obtainable by poly(acetylcyclotrimerization) of polyacetyl-functionalized or polyacetylated aromatics and/or polyacetyl-functionalized or polyacetylated polycycles, and to the different uses or possible applications of this unit.
US09034787B2 Ceramic articles and methods of producing ceramic articles
A ceramic article may comprise a sintered phase ceramic composition comprising aluminum titanate (Al2TiO5), zirconium titanate (ZrTiO4), and a niobium-doped phase.
US09034785B2 Accelerator solution and process for curing curable resins
Solution suitable for accelerating the cure of a curable resin using a peroxide, said accelerator solution comprising (i) at least one organic solvent, (ii) a manganese salt, a copper salt, or a combination thereof, and (iii) an iron complex of a tetradentate, pentadentate or hexadentate nitrogen donor ligand.
US09034780B2 Heavy aromatics processing catalyst and process of using the same
This disclosure relates to a catalyst system adapted for transalkylation a C9+ aromatic feedstock with a C6-C7 aromatic feedstock, comprising: (a) a first catalyst comprising a first molecular sieve having a Constraint Index in the range of 3-12 and 0.01 to 5 wt. % of at least one source of a first metal element of Groups 6-10; and (b) a second catalyst comprising a second molecular sieve having a Constraint Index less than 3 and 0 to 5 wt. % of at least one source of a second metal element of Groups 6-10, wherein the weight ratio of the first catalyst over the second catalyst is in the range of 5:95 to 75:25 and wherein the first catalyst is located in front of the second catalyst when they are brought into contacting with the C9+ aromatic feedstock and the C6-C7 aromatic feedstock in the present of hydrogen.
US09034778B2 Fail safe protective wrapping
Electrically conductive paths are positioned in and extend transversely across the width of the backing of strips of wrapping material. The electrically conductive paths provide means for conducting electrical current through spirally wrapped protective materials from the surrounding earth to voids formed adjacent the overlapped edges of the wrapping material and thus permit cathodic protection for pipe surfaces exposed to voids formed as a result of improper application or bonding failures of the wrapping material.
US09034776B2 Method to produce a composite material
Method of producing an elastic composite material comprising the step of impregnating a fiber fabric with a liquid epoxy system comprising a non-aromatic epoxy resin and a hardener, and curing the impregnated fabric, whereby the epoxy system exhibits a tensile modulus lower than 15 MPa after cure.
US09034774B2 Film forming method using plasma
This film forming method comprises: a first material gas supply step (A) wherein a first raw material gas is supplied over the substrate to be processed so that a first chemical adsorption layer, which is adsorbed on the substrate by means of the first raw material gas is formed on the substrate to be processed, a second material gas supply step (C) wherein a second raw material that is different from the first raw material gas is supplied over the substrate, on which the first chemical adsorption layer has been formed, so that a second chemical adsorption layer, which is adsorbed by means of the second raw material gas, is formed on the first chemical adsorption layer; and a plasma processing step (E) wherein a plasma processing is carried on at least the first and second chemical adsorption layers using microwave plasma.
US09034773B2 Removal of native oxide with high selectivity
Provided are methods and systems for removing a native silicon oxide layer on a wafer. In a non-sequential approach, a wafer is provided with a native silicon oxide layer on a polysilicon layer. An etchant including a hydrogen-based species and a fluorine-based species is introduced, exposed to a plasma, and flowed onto the wafer at a relatively low temperature. The wafer is then heated to a slightly elevated temperature to substantially remove the native oxide layer. In a sequential approach, a wafer is provided with a native silicon oxide layer. A first etchant including a hydrogen-based species and a fluorine-based species is flowed onto the wafer. Then the wafer is heated to a slightly elevated temperature, a second etchant is flowed towards the wafer, and the second etchant is exposed to a plasma to complete the removal of the native silicon oxide layer and to initiate removal of another layer such as a polysilicon layer.
US09034768B2 Depositing tungsten into high aspect ratio features
Methods and apparatuses for filling high aspect ratio features with tungsten-containing materials are provided. The method involves providing a partially fabricated semiconductor substrate and depositing a tungsten-containing layer on the substrate surface to partially fill one or more high aspect ratio features. The method continues with selective removal of a portion of the deposited layer such that more material is removed near the feature opening than inside the feature. In certain embodiments, removal may be performed at mass-transport limited conditions with less etchant available inside the feature than near its opening. Etchant species are activated before being introduced into the processing chamber and/or while inside the chamber. In specific embodiments, recombination of the activated species is substantially limited and/or controlled during removal, e.g., operation is performed at less than about 250° C. and/or less than about 5 Torr.
US09034767B1 Facilitating mask pattern formation
Mask pattern formation is facilitated by: providing a mask structure including at least one sacrificial spacing structure disposed above a substrate structure; disposing a spacer layer conformally over the mask structure; selectively removing the spacer layer, leaving, at least in part, sidewall spacers along sidewalls of the at least one sacrificial spacing structure, and providing at least one additional sacrificial spacer over the substrate structure, one additional sacrificial spacer of the at least one additional sacrificial spacer being disposed in set spaced relation to the at least one sacrificial spacing structure; and removing the at least one sacrificial spacing structure, leaving the sidewall spacers and the at least one additional sacrificial spacer over the substrate structure as part of a mask pattern.
US09034764B2 Method of forming wide trenches using a sacrificial silicon slab
A method of forming an encapsulated wide trench includes providing a silicon on oxide insulator (SOI) wafer, defining a first side of a first sacrificial silicon slab by etching a first trench in a silicon layer of the SOI wafer, defining a second side of the first sacrificial silicon slab by etching a second trench in the silicon layer, forming a first sacrificial oxide portion in the first trench, forming a second sacrificial oxide portion in the second trench, forming a polysilicon layer above the first sacrificial oxide portion and the second sacrificial oxide portion, and etching the first sacrificial oxide portion and the second sacrificial oxide portion.
US09034761B2 Heteroleptic (allyl)(pyrroles-2-aldiminate) metal-containing precursors, their synthesis and vapor deposition thereof to deposit metal-containing films
Disclosed are metal-containing precursors having the formula Compound (I) wherein: —M is a metal selected from Ni, Co, Mn, Pd; and —each of R-1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are independently selected from H; a C1-C4 linear, branched, or cyclic alkyl group; a C1-C4 linear, branched, or cyclic alkylsilyl group (mono, bis, or tris alkyl); a C1-C4 linear, branched, or cyclic alkylamino group; or a C1-C4 linear, branched, or cyclic fluoroalkyl group. Also disclosed are methods of synthesizing and using the disclosed metal-containing precursors to deposit metal-containing films on a substrate via a vapor deposition process.
US09034759B2 Method for forming interlevel dielectric (ILD) layer
A method for forming an interlevel dielectric (ILD) layer includes the following steps. A MOS transistor on a substrate is provided. A first undoped oxide layer is deposited to cover the substrate and the MOS transistor. The first undoped oxide layer is planarized. A phosphorus containing oxide layer is deposited on the first undoped oxide layer. A second undoped oxide layer is deposited on the phosphorus containing oxide layer.
US09034757B2 Method for manufacturing a component having an electrical through-connection
A method for manufacturing a component having an electrical through-connection is described. The method includes the following steps: providing a semiconductor substrate having a front side and a back side opposite from the front side, producing an insulating trench, which annularly surrounds a contact area, on the front side of the semiconductor substrate, filling the insulating trench with an insulating material, producing an electrical contact structure on the front side of the semiconductor substrate by depositing an electrically conductive material in the contact area, removing the semiconductor material remaining in the contact area on the back side of the semiconductor substrate in order to produce a contact hole which opens up the bottom side of the contact structure, and depositing a metallic material in the contact hole in order to electrically connect the electrical contact structure to the back side of the semiconductor substrate.
US09034753B2 Method of forming conductive contacts on a semiconductor device with embedded memory and the resulting device
A method is disclosed that includes forming a conductive logic contact in a logic area of a semiconductor device, forming a bit line contact and a capacitor contact in a memory array of the semiconductor device, and performing at least one first common process to form a first metallization layer comprising a first conductive line in the logic area that is conductively coupled to the conductive logic contact and a bit line in the memory array that is conductively coupled to the bit line contact. The method further includes performing at least one second common process to form a second metallization layer comprising a first conductive structure conductively coupled to the first conductive line in the logic area and a second conductive structure in the memory array that that is conductively coupled to the capacitor contact.
US09034748B2 Process variability tolerant hard mask for replacement metal gate finFET devices
Embodiments include a method comprising depositing a hard mask layer over a first layer, the hard mask layer including; lower hard mask layer, hard mask stop layer, and upper hard mask. The hard mask layer and the first layer are patterned and a spacer deposited on the patterned sidewall. The upper hard mask layer and top portion of the spacer are removed by selective etching with respect to the hard mask stop layer, the remaining spacer material extending to a first predetermined position on the sidewall. The hard mask stop layer is removed by selective etching with respect to the lower hard mask layer and spacer. The first hard mask layer and top portion of the spacer are removed by selectively etching the lower hard mask layer and the spacer with respect to the first layer, the remaining spacer material extending to a second predetermined position on the sidewall.
US09034745B2 Semiconductor device and method for manufacturing the same
A semiconductor device and a method for manufacturing the same are disclosed. A semiconductor device includes a contact hole formed over a semiconductor substrate so as to open an active region, a contact plug coupled to the active region in the contact hole and having a height lower than that of the contact hole, and a bit line that is coupled to the contact plug and has the same width as the contact plug. When forming a bit line of a cell region, a barrier metal layer is formed between a bit line contact plug and a bit line conductive layer, such that interfacial resistance is reduced, a thickness of the bit line conductive layer is increased, conductivity is improved, and the height of overall bit line is reduced, resulting in reduction in parasitic capacitance.
US09034741B2 Halo region formation by epitaxial growth
A semiconductor device and method for manufacturing the same, wherein the method includes fabrication of field effect transistors (FET). The method includes growing a doped epitaxial halo region in a plurality of sigma-shaped source and drain recesses within a semiconductor substrate. An epitaxial stressor material is grown within the sigma-shaped source and drain recesses surrounded by the doped epitaxial halo forming source and drain regions with controlled current depletion towards the channel region to improve device performance. Selective growth of epitaxial regions allows for control of dopants profile and hence tailored and enhanced carrier mobility within the device.
US09034739B2 Semiconductor devices and fabrication methods
A method of making a semiconductor device comprises: providing a semiconductor wafer having a semiconductor layer; forming a first mask layer over the semiconductor layer; forming a second mask layer over the first mask layer; annealing the second mask layer to form islands; etching through the first mask layer and the semiconductor layer using the islands as a mask to form an array of pillars; and growing semiconductor material between the pillars and then over the tops of the pillars.
US09034726B2 Semiconductor process
A semiconductor structure is located in a recess of a substrate. The semiconductor structure includes a liner, a silicon rich layer and a filling material. The liner is located on the surface of the recess. The silicon rich layer is located on the liner. The filling material is located on the silicon rich layer and fills the recess. Furthermore, a semiconductor process forming said semiconductor structure is also provided.
US09034724B2 Semiconductor substrate for photonic and electronic structures and method of manufacture
A method of forming a substrate with isolation areas suitable for integration of electronic and photonic devices is provided. A common reticle and photolithographic technique is used to fabricate a mask defining openings for etching first and second trench isolation areas in a substrate, with the openings for the second trench isolation areas being wider than the openings for the first trench isolation areas. The first and second trench isolation areas are etched in the substrate through the mask. The second trench isolation areas are further etched to the deeper than the first trench isolation areas. The trench isolation areas are filled with oxide material. Electrical devices can be formed on the substrate and electrically isolated by the first trench isolation areas and photonic devices can be formed over the second trench isolation areas and be optically isolated from the substrate.
US09034722B2 Method of removing a compound semiconductor layer from a compound semiconductor device
A method for manufacturing a compound semiconductor device so as to separate a first substrate from a compound semiconductor laminated structure which includes forming a first compound semiconductor layer over a first substrate containing AlxGa1-xN (0≦x<1) and having a first band gap; forming a second compound semiconductor layer over the first compound semiconductor layer containing AlyInzGa1-y-zN (0
US09034716B2 Method of making a FinFET device
A FinFET device is fabricated by first receiving a FinFET precursor. The FinFET precursor includes a substrate, fins on the substrate, isolation regions on sides of the fins and dummy gate stacks on the substrate including wrapping a portion of the fin, which is referred to as a gate channel region. The dummy gate stacks is removed to form a gate trench and a gate dielectric layer is deposited in the gate trench. A metal stressor layer (MSL) is conformably deposited on the gate dielectric layer. A capping layer is deposited on the MSL. A thermal treatment is applied to the MSL to achieve a volume expansion. Then the capping layer is removed and a metal gate (MG) is formed on the MSL.
US09034713B2 Method of fabricating high voltage metal-oxide-semiconductor transistor device
The present invention provides a method of fabricating a HV MOS transistor device, including forming a deep well in a substrate, and the deep well; forming a first doped region in the deep well, and the first doped region, wherein a doping concentration of the first doped region and a doping concentration of the deep well in at least one electric field concentration region has a first ratio, the doping concentration of the first doped region and the doping concentration of the deep well outside the electric field concentration region has a second ratio, and the first ratio is greater than the second ratio; and forming a high voltage well in the substrate, and forming a second doped region and a third doped region respectively in the deep well and in the high voltage well.
US09034705B2 Method of forming semiconductor device
A method of forming a semiconductor device is disclosed. At least one gate structure is provided on a substrate, wherein the gate structure includes a first spacer formed on a sidewall of a gate. A first disposable spacer material layer is deposited on the substrate covering the gate structure. The first disposable spacer material layer is etched to form a first disposable spacer on the first spacer. A second disposable spacer material layer is deposited on the substrate covering the gate structure. The second disposable spacer material layer is etched to form a second disposable spacer on the first disposable spacer. A portion of the substrate is removed, by using the first and second disposable spacers as a mask, so as to form two recesses in the substrate beside the gate structure. A stress-inducing layer is formed in the recesses.
US09034700B1 Integrated circuit devices including finFETs and methods of forming the same
Integrated circuit devices including Fin field effect transistors (finFETs) and methods of forming those devices are provided. The methods may include forming a fin on a substrate and forming a gate line on the fin. The method may also include forming a first recess in the fin having a first width and a first depth and forming a second recess in the first recess having a second width that is less than the first width and having a second depth that is greater than the first depth. The method may further include forming a source/drain region in the first and second recesses.
US09034695B2 Integrated thermal solutions for packaging integrated circuits
A method includes attaching a wafer on a carrier through an adhesive, and forming trenches in the carrier to convert the carrier into a heat sink. The heat sink, the carrier, and the adhesive are sawed into a plurality of packages.
US09034691B2 Thin film transistor, thin film transistor array panel including the same, and method of manufacturing the same
A thin film transistor, a thin film transistor array panel including the same, and a method of manufacturing the same are provided, wherein the thin film transistor includes a channel region including an oxide semiconductor, a source region and a drain region connected to the channel region and facing each other at both sides with respect to the channel region, an insulating layer positioned on the channel region, and a gate electrode positioned on the insulating layer, wherein an edge boundary of the gate electrode and an edge boundary of the channel region are substantially aligned.
US09034685B2 Methodology for forming pnictide compositions suitable for use in microelectronic devices
The present invention provides methods for making pnictide compositions, particularly photoactive and/or semiconductive pnictides. In many embodiments, these compositions are in the form of thin films grown on a wide range of suitable substrates to be incorporated into a wide range of microelectronic devices, including photovoltaic devices, photodetectors, light emitting diodes, betavoltaic devices, thermoelectric devices, transistors, other optoelectronic devices, and the like. As an overview, the present invention prepares these compositions from suitable source compounds in which a vapor flux is derived from a source compound in a first processing zone, the vapor flux is treated in a second processing zone distinct from the first processing zone, and then the treated vapor flux, optionally in combination with one or more other ingredients, is used to grow pnictide films on a suitable substrate.
US09034679B2 Method for fabricating multiple types of MEMS devices
A method entails providing a substrate with a structural layer having a thickness. A partial etch process is performed at locations on the structural layer so that a portion of the structural layer remains at the locations. An oxidation process is performed at the locations which consumes the remaining portion of the structural layer and forms an oxide having a thickness that is similar to the thickness of the structural layer. The oxide electrically isolates microstructures in the structural layer, thus producing a structure. A device substrate is coupled to the structure such that a cavity is formed between them. An active region is formed in the device substrate. A short etch process can be performed to expose the microstructures from an overlying oxide layer.
US09034672B2 Method for manufacturing light-emitting devices
A method of manufacturing a light-emitting device includes forming a first optical element on a first carrier, wherein the first optical element comprises an opening; forming a light-emitting element in the opening; forming a second optical element on the light-emitting element; forming a second carrier on the first optical element and the second optical element; removing the first carrier after forming the second carrier on the first optical element and the second optical element; and forming two separated conductive structures under the first optical element.
US09034670B2 Solar cell and method for manufacturing such a solar cell
A method (100; 100a; 100b; 100c) for manufacturing a solar cell from a semiconductor substrate (1) of a first conductivity type, the semiconductor substrate having a front surface (2) and a back surface (3). The method includes in a sequence: texturing (102) the front surface to create a textured front surface (2a); creating (103) by diffusion of a dopant of the first conductivity type a first conductivity-type doped layer (2c) in the textured front surface and a back surface field layer (4) of the first conductivity type in the back surface; removing (105; 104a) the first conductivity-type doped layer from the textured front surface by an etching process adapted for retaining texture of the textured front surface; creating (106) a layer of a second conductivity type (6) on the textured front surface by diffusion of a dopant of the second conductivity type into the textured front surface.
US09034667B2 Apparatus and method for endpoint detection during electronic sample preparation
A method for detecting an endpoint during removal of material from an electronic device includes while removing material from an electronic device-under-test (DUT) using a tip driven by a spindle, applying an input signal to the DUT via the tip and using an output signal received from one of the DUT and a mounting plate to which the DUT is attached to determine an endpoint for removal of material.
US09034664B2 Method to resolve hollow metal defects in interconnects
A method of repairing hollow metal void defects in interconnects and resulting structures. After polishing interconnects, hollow metal void defects become visible. The locations of the defects are largely predictable. A repair method patterns a mask material to have openings over the interconnects (and, sometimes, the adjacent dielectric layer) where defects are likely to appear. A local metal cap is formed in the mask openings to repair the defect. A dielectric cap covers the local metal cap and any recesses formed in the adjacent dielectric layer.
US09034662B2 MR enhancing layer (MREL) for spintronic devices
The performance of an MR device has been improved by inserting one or more Magneto-Resistance Enhancing Layers (MRELs) into approximately the center of one or more of the magnetic layers such as an inner pinned (AP1) layer, spin injection layer (SIL), field generation layer (FGL), and a free layer. An MREL is a layer of a low band gap, high electron mobility semiconductor such as ZnO or a semimetal such as Bi. The MREL may further comprise a first conductive layer that contacts a bottom surface of the semiconductor or semimetal layer, and a second conductive layer that contacts a top surface of the semiconductor or semimetal layer.
US09034660B2 Detection of analytes via nanoparticle-labeled substances with electromagnetic read-write heads
A first set of antibodies are bonded to a substrate, and are exposed to and bonded with target antigens. A second set of antibodies are bonded to nanoparticles, and the nanoparticle labeled antibodies are exposed to the targeted antigens. An electromagnetic write-head magnetizes the nanoparticles, and then a read-sensor detects the freshly magnetized nanoparticles. The substrate comprises a flexible film or a Peltier material to allow selective heating and cooling of the antigens and antibodies. Nanoparticles of different magnetic properties may be selectively paired with antibodies associated with different antigens to allow different antigens to be detected upon a single scan by the read-sensor.
US09034656B2 Signal amplification in lateral flow and related immunoassays
The present invention provides methods, devices, compositions (e.g., capture complexes), and kits useful for enhancing the detection of antibodies in a test sample. The methods, devices, and compositions utilize detectable Fc-binding molecules such as Protein A, Protein G, and/or an Fc-specific antibody to amplify the signal of a detected antibody in immunoassays, such as lateral flow assays.
US09034652B2 Colloidal Coomassie stain
Colloidal formulation for staining proteins and methods of their use are provided.
US09034650B2 Site-specific serine recombinases and methods of their use
The present invention provides a method for obtaining site-specific recombination in a eukaryotic cell, the method comprising providing a eukaryotic cell that comprises a first recombination attachment site and a second recombination attachment site; contacting the first and second recombination attachment sites with a prokaryotic recombinase polypeptide, resulting in recombination between the recombination attachment sites, wherein the recombinase polypeptide can mediate recombination between the first and second recombination attachment sites, the first recombination attachment site is a phage genomic recombination attachment site (attP) or a bacterial genomic recombination attachment site (attB), the second recombination site is attB or attP, and the recombinase is selected from the group consisting of a Listeria monocytogenes phage recombinase, a Streptococcus pyogenes phage recombinase, a Bacillus subtilis phage recombinase, a Mycobacterium tuberculosis phage recombinase and a Mycobacterium smegmatis phage recombinase, provided that when the first recombination attachment site is attB, the second recombination attachment site is attP and when the first recombination attachment site is attP, the second recombination attachment site is attB. The invention also describes compositions, vectors, and methods of use thereof, for the generation of transgenic cells, tissues, plants, and animals. The compositions, vectors and methods of the present invention are also useful in gene therapy applications.
US09034640B2 Bioreactor for controlling cellular growth
A system includes a first chamber configured to receive a hydrogel and a scaffold comprising a cell, wherein the hydrogel is in fluid communication with the scaffold, and wherein the hydrogel includes a plurality of unidirectional pores. The system also includes a second chamber configured to receive a first fluid and a second fluid, wherein the second chamber includes a wall that separates the first fluid from the second fluid. The system further includes a porous membrane configured to separate the first chamber from the second chamber. The wall is configured to move along the porous membrane as cellular extensions are projected into at least a portion of the plurality of unidirectional pores of the hydrogel.
US09034634B2 Sample metering device and assay device with integrated sample dilution
In one embodiment, the invention is to a sample metering device, comprising a sample holding chamber oriented between a sample entry port and a sample isolation unit and having a diluent introduction port disposed therebetween for introduction of a diluent into the sample holding chamber. The volume within the sample holding chamber between the diluent introduction port and the sample isolation unit defines a metered volume of a sample for analysis. In another embodiment, the invention is to an apparatus and method for rapid determination of analytes in liquid samples by various assays including immunoassays incorporating a sample dilution feature, preferably suitable for low range sample dilution, and preferably capable of being used in the point-of-care diagnostic field.
US09034632B2 Compositions and methods for culturing microorganisms
This disclosure provides compositions and methods for culturing microorganisms. The disclosure includes mixtures of different microorganisms, especially mixtures of cyanobacteria with fermentative microorganisms. For example, methods and compositions related to co-cultures of yeast and cyanobacteria are provided. Also provided are feedstocks derived from cyanobacteria as well as methods of making such feedstocks and methods of culturing microorganisms in such feedstocks.
US09034629B2 Recombinant synthesis of medium chain-length alkanes
The present disclosure identifies methods and compositions for modifying photoautotrophic organisms as hosts, such that the organisms efficiently produce alkanes, and in particular the use of such organisms for the commercial production of alkanes and related molecules. Other materials, methods, and compositions are also described.
US09034627B2 Method for producing glucosidase, enzyme composition, and method for hydrolyzing biomass
A method for producing a mutant glucosidase includes introducing DNA encoding a secretion signal sequence and DNA encoding Asn-X-Ser or Asn-X-Thr into DNA encoding a glucosidase derived from a thermophile, and introducing the resulting DNA into a eukaryotic microorganism and expressing it as a secretory protein. An enzyme composition contains the mutant glucosidase.
US09034624B2 Process for the synthesis of conjugates of glycosaminoglycanes (GAG) with biologically active molecules, polymeric conjugates and relative uses thereof
The present invention relates to a process for the synthesis of conjugates of glycosaminoglycanes (GAG) with biologically active molecules of varying nature, comprising small molecules and macro-molecules. In particular, the present invention relates to the conjugation of hyaluronic acid (HA) and its derivatives with polypeptides and proteins with a biological action, such as, for example, interferons, erythropoietins, growth factors, insulin, cytokines, antibodies and hormones.An object of the present invention also relates to isolatable intermediates obtained by the partial or total reaction of GAG with protected amino aldehydes in the conjugation process mentioned above.
US09034623B2 Nanoengineered biophotonic hybrid device
Apparatus, compositions, methods, and articles of manufacture are disclosed relating to the design and production of biological components and/or their incorporation in devices and systems, including biohybrid photosensitive devices and systems. In some embodiments, biological components include light antenna structures that collect light and emit Stokes-shifted light to a photoactive non-biological component. In some embodiments, the characteristics of biological components are engineered via force-adaptation of an organism or adaptive system. In some embodiments, biological components are modified by removing reaction centers or other structure not contributing to desired performance.
US09034622B2 Preparation for photodynamic control of microorganisms and use thereof
The invention relates to a preparation for the photodynamic control of micro-organisms, said preparation being in a liquid or pasty form and containing a photosensitizer which comprises a dyestuff and produces singlet oxygen when irradiated by means of light. The micro-organisms can be marked by means of the dyestuff. The aim of the invention is to improve said preparation in order to enable an improved photodynamic control. To this end, the preparation contains an active ingredient for amplifying or weakening the oxidative action of the singulet oxygen by chemical manipulation of the dyestuff or the nanoenvironment thereof. In a particular form of embodiment, a rinsing solution is used before the irradiation.
US09034621B2 Method and device for operating a fermentation plant
A method for operating a fermentation plant with at least one digester that is supplied with a substrate. The substrate is percolated using a percolate from a percolate container and biogas that is generated via the percolation process in the digester or/and in the percolate container is drawn off. The drawn off biogas is treated in a biogas treatment device and the CO2-containing exhaust gas that is generated during the treatment is introduced into the digester using a purge line, for forcing out and drawing off the biogas that was generated in the digester. Alternatively CO2-containing biogas that was generated in an additional digester in a different fermentation process can be introduced into the digester for forcing out and drawing off the biogas that was generated in the digester. The CO2-containing purge gas is forced to pass through the substrate dislodging any trapped biogas.
US09034618B2 Method for sustaining microorganism culture in syngas fermentation process in decreased concentration or absence of various substrates
The present invention relates to methods for sustaining microorganism culture in a syngas fermentation reactor in decreased concentration or absence of various substrates comprising: adding carbon dioxide and optionally alcohol; maintaining free acetic acid concentrations; and performing the above mentioned steps within specified time.
US09034617B2 Processes for the anaerobic bioconverison of syngas to oxygenated organic compound with in situ protection from hydrogen cyanide
Processes are disclosed for the anaerobic bioconversion of syngas to oxygenated organic compound that use an in situ method for protecting the microorganisms from hydrogen cyanide contained in the syngas that passes to the fermentation broth. The fermentation broth is maintained at a pH of between about 4 and 6, and dissolved metal cation of one or more of iron, cobalt, nickel and zinc is provided to the fermentation broth in an amount sufficient to form, under the conditions of the fermentation broth, a substantially insoluble metal complex with the metal cation and cyanide anion. The rate of formation of the insoluble complex is sufficiently high that that the amount of cyanide that is taken up by microorganisms does not result in an undue adverse effect on the population of microorganisms.
US09034616B2 Butanal production using engineered Streptomyces coelicolor
A method of producing butanal by optimizing the growth of Streptomyces using cellulose as food source, overexpressing a key ‘gate’ enzyme in butyric acid/butyraldehyde production, and knocking out the isobutyryl-CoA synthase gene to shunt the pathway. Optionally, the produced butanal can be isolated and converted into butanol.
US09034615B2 Glycolic acid production by fermentation from renewable resources
The present invention provides a method for the biological production of glycolic acid from a fermentable carbon source in a microorganism. In one aspect of the present invention, a process for the conversion of glucose to glycolic acid is achieved by the use of a recombinant organism comprising a host E. coli transformed i) to attenuate the glyoxylate consuming pathways to other compounds than glycolate ii) to use an NADPH glyoxylate reductase to convert glyoxylate to glycolate iii) to attenuate the level of all the glycolate metabolizing enzymes and iv) increase the flux in the glyoxylate pathway. In another aspect of the present invention, the process for the production of glycolic acid from a fermentable carbon source, using a recombinant E. coli, is improved by increasing the NADPH availability in the cells. Optionally the glycolic acid produced can be purified through a step of polymerization to at least glycolic acid dimers and recovered by depolymerization from glycolic acid dimers, oligomers and/or polymers.
US09034610B2 Polypeptides and biosynthetic pathways for the production of monatin and its precursors
Methods and compositions that can be used to make monatin from glucose, tryptophan, indole-3-lactic acid, indole-3-pyruvate, and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid, are provided. Methods are also disclosed for producing the indole-3-pyruvate and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid intermediates. Compositions provided include nucleic acid molecules, polypeptides, chemical structures, and cells. Methods include in vitro and in vivo processes, and the in vitro methods include chemical reactions.
US09034609B2 Bio-engineered multi-enzyme complexes comprising xylanases and uses thereof
The present invention relates to bio-engineered multi-enzyme complexes having synergistic enzyme activity comprising xylanases and optionally further comprising additional carbohydrate active enzymes. Such complexes are advantageous for degrading recalcitrant cellulosic biomass.
US09034606B2 Detection of an amplification reaction product using pH-sensitive dyes
Methods are provided for a rapid, low cost approach to monitoring an amplification reaction. This includes monitoring the progress of isothermal or PCR amplification reactions to completion using pH-sensitive dyes that are either colored or fluorescent. Compositions are described that include a mixture of a DNA polymerase, deoxyribonucleotide triphosphate and a weak buffer of less than 1 mM Tris or equivalent or no buffer.
US09034605B2 Reagents and methods for PCR
Modified double-stranded oligonucleotides that have terminal regions on each of their strands, that have a hybrid length of 6-50 nucleotides long, that have a melting temperature Tm of at least 32° C., and that include 2-4 modifying groups, each covalently attached to a different terminal region, preferably to a terminal nucleotide, said modifying groups being polycyclic substituents that do not have bulky portions that are non-planar, said modified oligonucleotide being capable of binding to the 5′ ex-nuclease domains of DNA polymerases and, when included in a PCR or other primer-dependent DNA amplification reaction at a concentration, generally not more than 2000 nM, that is effective for at least one of the functions of suppressing mispriming, increasing polymerase selectivity against 3′ terminal mismatches, increasing polymerase selectivity against AT-rich 3′ ends, reducing scatter among replicates, suppressing polymerase 5′ exonuclease activity, and inhibiting polymerase activity; as well as amplification reaction mixtures containing such modified double-stranded oligonucleotides, and amplification reactions, amplification assays and kits that include such modified double-stranded oligonucleotides.
US09034602B2 Modified beta-lactamases and methods and uses related thereto
The present invention relates to pharmaceuticals and modified beta-lactamases. Specifically, the invention relates to novel recombinant beta-lactamases and pharmaceutical compositions comprising the beta-lactamases. Also, the present invention relates to methods for modifying a beta-lactamase, producing the beta-lactamase and treating or preventing beta-lactam antibiotic induced adverse effects. Furthermore, the present invention relates to the beta-lactamase for use as a medicament and to the use of the beta-lactamase in the manufacture of a medicament for treating or preventing beta-lactam antibiotics induced adverse effects. Still further, the invention relates to a polynucleotide and a host cell comprising the polynucleotide.
US09034598B2 Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of leucyl-tRNA synthetases
Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
US09034596B1 Method for fluorescent staining of cellular and intracellular membranes
The method for fluorescent staining of cellular and intracellular membranes includes contacting a cell sample, such as a cell culture, with a fluorescent probe including Zn(II) meso-tetrakis(N-n-hexylpyridinium-4-yl)porphyrin tetrachloride (ZnTnHex-4-PyPCl4). The fluorescent probe is an amphiphilic, water-soluble compound. The fluorescent probe does not interfere with cell culture media components or other staining products. The fluorescent probe is not harmful to cells.
US09034593B2 Vaginal indicator to detect biomarkers of good health
A diagnostic kit for biomarkers of beneficial vaginal health is described. The kit includes a first detection zone within which a D-lactic acid detection signal is capable of being generated, wherein the presence or quantity of D-lactic acid, is determinable from the D-lactic acid detection signal. The kit further includes a second detection zone within which a hydrogen peroxide detection signal is capable of being generated, wherein the presence or quantity of hydrogen peroxide, is determinable from the hydrogen peroxide detection signal.
US09034589B2 Magnetic separation of cells
An apparatus, system, and method for magnetic separation of cells are disclosed. By combining inkjet printing technology and magnetic labeling of cells, accurate cell counts are obtained using an optical microscope. Mouse CD4+ lymphocytes are attached to micron sized magnetic beads and printed through a modified, commercial inkjet printer. The labeled cells are then attached to a glass slide covering a permanent magnet. Cell counts can be obtained by use of regular and inverted optical microscopes and imaging software. The magnetically-labeled beads are collected for evaluation on a modified polymer coupon that is placed in front of a permanent magnet and the unlabeled cells fall into an excess container. Flow cytometry results verify the presence of the CD4+ protein on the LBRM-33 lymphocytes membrane. Protein-specific attachment of magnetic microspheres to the lymphocytes is utilized for sorting CD4+ lymphocytes.
US09034587B2 Methods of diagnosing cancer
A method of diagnosing cancer or a pre-malignant lesion is disclosed. The method comprises determining a level of CD24 expressed on peripheral blood cells of a subject in need thereof, wherein the level of CD24 above a predetermined threshold is indicative of the cancer or the pre-malignant lesion.
US09034585B2 Diabetes-related biomarkers and methods of use thereof
The invention describes biomarkers which can be used to predict the likelihood that an individual will develop Diabetes. The biomarkers can also be used to screen large groups in order to identify individuals at risk of developing Diabetes.
US09034573B1 Molecular structure of RHD negative
The RH blood group antigens derive from two genes, RHD and RHCE, that are located at chromosomal position 1p34.1-1p36. In whites, a “cde” haplotype with a deletion of the whole RHD gene occurs with a frequency of about 40%. The relative position of the two RH genes and the location of the RHD deletion was previously unknown. A model for the RH locus was developed using RHD- and RHCE-related nucleotide sequences deposited in nucleotide sequence databases along with PCR and nucleotide sequencing. The open reading frames of both RH genes had opposite orientations. The 3′ ends of the genes faced each other and were separated by about 30,000 base pairs (bp) that contained the SMP1 gene. The RHD gene was flanked by two DNA segments, dubbed Rhesus boxes, that had about 9,000 bp length, 98.6% homology, and identical orientation. The Rhesus box contained the RHD deletion occurring within a stretch of 1,463 bp of identity. A PCR-SSP and a PCR-RFLP for specific detection of the RHD deletion was devised. The molecular structure of the RH gene locus explains mechanisms for generating RHD/RHCE hybrid alleles and the RHD deletion. Specific detection of the RHD negative genotype is now possible. The utility of the RHD PCR is limited by the incomplete knowledge of presumably rare RHD positive alleles in D negative. 1068 serologically RhD-negative samples were checked by PCR-SSP for the presence of RHD specific nucleotide sequences. 48 Samples were positive and were then assigned to specific PCR patterns or distinct RHD alleles. Seven PCR patterns were identified, three of which were not described previously, and four new RHD alleles that were RhD-negative because of nonsense or splice mutations. Another three new haplotypes represented a Del phenotype. Three samples were mislabeled weak D or partial D. The sensitivity of current RHD PCR methods exceeded routine serology. As the molecular background of D-negative alleles causing false-positive RHD PCR in whites is more heterogeneous than anticipated, improvements in test specificity will critically depend on detecting RhD-negative RHD positive alleles.
US09034572B2 Calibratable sensor unit for reaction vessels
The present invention relates to a calibration method of a sensor unit connected to a reaction vessel, wherein the sensor unit comprises at least one sensor device configured to be calibrated, at least one compartment containing a calibrating agent, and a housing. The method comprising inserting a sensitive element of the at least one sensor device into a compartment of the sensor unit containing a calibrating agent, withdrawing the sensitive element from the compartment; inserting the sensitive element into the reaction vessel and locking the sensor device in position, wherein the steps of the method are irreversible.
US09034570B2 Methods of forming patterns
Some embodiments include methods of forming patterns of openings. The methods may include forming spaced features over a substrate. The features may have tops and may have sidewalls extending downwardly from the tops. A first material may be formed along the tops and sidewalls of the features. The first material may be formed by spin-casting a conformal layer of the first material across the features, or by selective deposition along the features relative to the substrate. After the first material is formed, fill material may be provided between the features while leaving regions of the first material exposed. The exposed regions of the first material may then be selectively removed relative to both the fill material and the features to create the pattern of openings.
US09034567B2 Method for manufacturing liquid crystal display device, and liquid crystal display device
Provided is a method for manufacturing a liquid crystal display device that includes a photoalignment film. The photoalignment film is formed from a liquid crystal alignment agent, and aligns liquid crystal molecules horizontally to the main face of the at least one of the substrates. The liquid crystal alignment agent contains a solvent and at least two kinds of polyamic acids or their derivatives obtained by reacting diamine and tetracarboxylic dianhydride. At least two of the diamines and at least one of the tetracarboxylic dianhydrides are compounds represented by predetermined formulas. The method includes the steps of: (1) forming the film of the liquid crystal alignment agent; (2) pre-baking the film; (3) irradiating the pre-baked film with light; and (4) post-baking the irradiated film, the step (4) including an operation of post-baking the film multiple times at temperatures ranging from low to high temperatures.
US09034566B2 Resin composition for forming optical waveguide and optical waveguide using the composition
A resin composition for forming an optical waveguide brings together excellent bending resistance, a low refractive index, and low tackiness suitable for a roll-to-roll (R-to-R) process as a material for forming an optical waveguide, in particular, a material for forming a clad layer. The resin composition for forming an optical waveguide to be used in formation of an optical waveguide includes a polyvinyl acetal compound having a structural unit represented by the following general formula (1) as a main component: in the formula (1), R represents an alkyl group having 1 to 3 carbon atoms, and k, m, and n represent ratios of respective repeating units in a main chain and each represent an integer of 1 or more.
US09034561B2 Photosensitive composition comprising an acrylate compound
The present invention relates to a photosensitive composition including an acrylate-based compound having an adamantyl structure. It is possible to manufacture an organic thin film that is easily stripped without decreasing the strength of the thin film by using the photosensitive composition.
US09034555B2 Method for producing liquid developer
A method for producing a liquid developer containing toner particles containing a resin containing a polyester and a pigment, and an insulating liquid, wherein the toner particles are dispersed in the insulating liquid, including: step 1: melt-kneading the resin and the pigment, and pulverizing a melt-kneaded mixture to provide toner particles; step 2: dispersing the toner particles obtained in the step 1 in the insulating liquid in the presence of a basic dispersant to provide a dispersion of toner particles; and step 3: wet-milling the dispersion of toner particles obtained in the step 2 to provide a liquid developer, wherein the basic dispersant is an amide compound obtained by a reaction between a polyethyleneimine and a polyester (D) obtained by self-condensation of 12-hydroxystearic acid. The liquid developer obtained by the method of the present invention can be suitably used in development of latent images formed in, for example, an electrophotographic method, an electrostatic recording method, an electrostatic printing method, or the like.
US09034554B2 Method of producing gallium phthalocyanine crystal and method of producing electrophotographic photosensitive member using the method of producing gallium phthalocyanine crystal
Provided is a method of producing an electrophotographic photosensitive member having improved sensitivity and capable of outputting an image having less image defects due to a ghost phenomenon not only under a normal-temperature, normal-humidity environment but also under a low-temperature, low-humidity environment as a particularly severe condition. The method of producing a gallium phthalocyanine crystal includes subjecting a gallium phthalocyanine and a specific amine compound, which are added to a solvent, to a milling treatment to perform crystal transformation of the gallium phthalocyanine. In addition, the gallium phthalocyanine crystal is used in the photosensitive layer of the electrophotographic photosensitive member.
US09034549B2 Toner
A toner is provided that exhibits a satisfactory heat-resistant storability and an excellent low-temperature fixability. The toner has toner particles each of which contains at least a binder resin and a wax, and is characterized in that this toner is obtained by attaching a metal compound to the surface of the toner particle and thereafter performing a surface treatment with a hot air current; the binder resin contains at least a polyester resin; and the metal compound is formed by coordinating or bonding a specific aromatic oxycarboxylic acid to a metal.
US09034547B2 Electrophotography toner
Main performances of a toner are significantly affected by a shape and surface characteristics of toner particles. Using an external additive may be a factor that complicates control of surface characteristics of the toner particles, and anti-offset properties of toner change according to a wax and a binder composition at a surface portion of the toner particles. Provided is a toner usable in electrophotography, wherein the toner has improved durability, fixability, charging stability, and cleaning properties through an appropriate distribution of a binder, a wax, and an external additive on a surface portion of toner particles.
US09034544B2 Compound, charge transporting film, photoelectric conversion device, and electrophotographic photoreceptor using the compound, method of producing electrophotographic photoreceptor, process cartridge, and image forming apparatus
Provided is a compound represented by the following Formula (I): wherein in Formula (I), F represents a charge transporting skeleton, L represents a divalent linking group including a —(CH2)n—O— group, m represents an integer of from 1 to 8, and n represents an integer of from 3 to 6.
US09034543B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus
An electrophotographic photoreceptor includes a conductive substrate; a charge generating layer provided on the conductive substrate; a charge transporting layer provided on the charge generating layer, which is configured to include a charge transporting material and a polycarbonate; and an outermost surface layer provided on the charge transporting layer, which is constituted with a cured film formed of a composition including a chain polymerizable compound having at least a charge transporting skeleton and a chain polymerizable functional group in the same molecule, and has an A value represented by the following equation (1) being from 0.1 to 0.3, and a B value represented by the following equation (2) being 0.02 or less, each of which is determined by an Attenuated total reflection Fourier transform infrared spectroscopy: A=(S1/S13)−(S0/S03)  Equation (1) B=S2/S23  Equation (2).
US09034542B2 Method and system for forming patterns with charged particle beam lithography
In a method for fracturing or mask data preparation or mask process correction for charged particle beam lithography, a plurality of shots are determined that will form a pattern on a surface, where shots are determined so as to reduce sensitivity of the resulting pattern to changes in beam blur (βf). In some embodiments, the sensitivity to changes in βf is reduced by varying the charged particle surface dosage for a portion of the pattern. Methods for forming patterns on a surface, and for manufacturing an integrated circuit are also disclosed, in which pattern sensitivity to changes in βf is reduced.
US09034533B2 Fuel cell stack and fuel cell system with plurality of generation modules
A fuel cell has a structure in which generation modules are stacked. In each of the generation modules, there are cells are stacked. Each of the cells generates unitary power from fuel energy. A fuel cell system including the fuel stack operates either all or some of the generation modules in consideration of the quantity of power consumed by a load.
US09034523B2 Organosilicon polymer, solid electrolyte and solid-state lithium-ion battery
The present disclosure discloses an organosilicon polymer, a solid electrolyte comprising the organosilicon polymer, and a corresponding solid-state lithium-ion battery. The organosilicon polymer of the present disclosure is a polymer compound comprising both an inorganic backbone-chain structure and an organic side-chain structure, and has the characteristics of both the organic polymer and the inorganic polymer as well as many unique properties. Therefore, the solid electrolyte formed by the organosilicon polymer and the solid-state lithium-ion battery thereof have many good characteristics including a good lithium-ion-conduction capability, better resistance to high temperatures, a wider range of operating temperatures, and better thermal stability.
US09034522B2 Method of fabricating a patterned solid polymeric electrolyte
A method of fabricating a solid polymeric electrolyte having a pattern includes mixing constituents including a liquid electrolyte, a photo-crosslinking agent, and inorganic particles to form an electrolyte paste; dispersing together the constituents of the electrolyte paste; coating the electrolyte paste on a substrate; pressing the electrolyte paste with a patterned mold having a shape to copy the shape of the patterned mold onto the electrolyte paste and provide said pattern; and illuminating an ultraviolet light onto the electrolyte paste to induce a photo-crosslinking reaction and cure the photo-crosslinking agent of the electrolyte paste, wherein said solid polymeric electrolyte includes a polymer matrix having a mesh structure, the polymer matrix being formed of the cured photo-crosslinking agent; inorganic particles distributed in the polymer matrix; and a lithium salt and an organic solvent impregnated between the polymer matrix and the inorganic particles.
US09034521B2 Anode material of excellent conductivity and high power secondary battery employed with the same
Provided is an anode material for an electrode mix comprising a carbon material and a lithium titanium oxide (LTO), wherein a ratio of an average particle size of LTO relative to that of the carbon material is in a range of 0.1 to 20%, and LTO is distributed mainly on a surface of the carbon material. The anode material of the present invention can prevent excessive formation of a SEI film, and is of a high capacity due to a high energy density and exhibits excellent output characteristics and rate characteristics. Further, it has superior electrolyte wettability which consequently results in improved battery performance and life characteristics.
US09034520B2 Positive active material for lithium secondary battery
Disclosed is a positive active material for a lithium secondary battery. The positive active material includes a lithium molybdenum oxide having an X-ray diffraction (XRD) pattern with peaks at 11.5±2°, 21±2°, 38±2°, and 64±2° 2-theta (2θ) and represented by Formula 1: LixMoO3, where 1
US09034517B1 Capacitors having conditioned carbon for electrodes
There is provided an improvement for capacitors having activated carbon electrodes by the use of an electrolyte solution containing a carbonate of the formula RO(C═O)OR1 and a conductive salt such as a lithium salt or a quaternary ammonium salt at a concentration of from 0.6 to 3 mol/l.
US09034516B2 Materials prepared by metal extraction
A method for extracting ions from an active material for use in a battery electrode includes mixing the active material and an activating compound to form a mixture. The mixture is annealed such that an amount of ions is extracted from the active material, an amount of oxygen is liberated from the active material, and an activated active material is formed. Embodiments of the invention include the activated active material, the electrode, and the primary and secondary batteries formed from such activated active materials.
US09034514B2 Electric storage device
In order to accurately protect current collectors included in an electric storage device, the electric storage device includes an electric storage element 3 arranged inside an electric storage device case BC; an electrode terminal 5 arranged outside the electric storage device case; a current collector 4 including a first posture part FP and a second posture part SP, the first posture part FP extending along a surface of the electric storage device case on which the electrode terminal 5 is arranged, the second posture part SP extending from an end portion of the first posture part toward the side opposite to the electrode terminal, the current collector fixed at the first posture part FP by means of a fixing member 8 penetrating through an opening formed in the electric storage device case, the current collector supporting the electric storage element 3 by the second posture part SP, thereby electrically connecting the electrode terminal 5 and the electric storage element 3; and a reinforcing member 13 arranged on the side of the first posture part FP where the electric storage element 3 is present, so as to extend longer toward the second posture part side than the fixing member 8, and sandwiched and fixed between the first posture part FP and the fixing member 8.
US09034513B2 Energy storage device
An energy storage device includes an electrode assembly, a container that contains the electrode assembly therein, a metallic cover member that closes the opening of the container and has a first fitting portion, and a current collector having a second fitting portion that is fitted to the first fitting portion in a fitted state. Thus, the compact energy storage device having a large capacity can suppress the positional deviation between the cover member and the current collector.
US09034511B2 Power storage apparatus, connection apparatus, power storage system, electronic device, motor-driven vehicle, and electric power system
A power storage apparatus having a battery unit housed in a case includes external terminals of positive and negative poles for providing, from outside the case, electrical connection to corresponding positive and negative poles of the battery unit; and electronic parts, wherein only when a connection with the battery unit is cut from at least one of the external terminals of both the poles, the electronic parts can be accessed.
US09034507B2 Arrangement having at least one battery
A battery pack having at least one battery with two electrical contacts in which a parallel circuit comprising a first and a second resistor is arranged between a first contact and a first pole, the first resistor switches off at a first temperature, the second resistor switches off at a second temperature, the first temperature is higher than the second temperature, and the first resistor has a higher current carrying capability than the second resistor. The circuit serves as fuse protection for the battery against overheating both when the battery is charging and when the battery is discharging.
US09034505B2 Battery housing for powered surgical tool
A battery housing for a driver of a powered surgical tool. The battery housing includes a casing with an opening for inserting at least one battery into the casing, a door for closing the opening when the door is in its closed position, and a driver interface for removably attaching the battery housing to a driver of a powered surgical tool. The door includes at least one part that is configured for being blocked by the driver when the door is moved out of its closed position and the battery housing is attached to the driver, such that the door cannot be opened when the battery housing is attached to the driver.
US09034504B2 Apparatus for preventing deformation of plastic battery pack case for a vehicle
Disclosed is an apparatus and method for preventing deformation of a plastic battery pack case for a vehicle, in which the side of the battery pack case is subjected to reverse deformation to absorb the deformation occurring after compression molding and to ensure the dimensions of a mounting portion of various components including battery packs, thereby ensuring an internal space of the battery pack case. To this end, the present invention provides an apparatus for preventing deformation of a plastic battery pack case for a vehicle, the apparatus including: a base having a case insertion space; a fixing portion for fixing a battery pack case inserted into the case insertion space; and a deformation producing portion inserted into the battery pack case and preventing the case from being deformed by pressing the inside of the case to be reversely deformed in the lateral direction.
US09034502B2 Battery installation structure for electric vehicles
A battery tray is fixed onto a front battery cross member lower and a rear battery cross member lower. The battery pack is mounted on the battery tray. The front battery cross member lower and the rear battery cross member lower come into contact with a deformable zone of the battery tray and the end face of each of battery cross member uppers at attachment portions. Space is created between the battery pack and the battery cross member uppers. The battery cross member uppers are welded so that a deformable zone having relatively low rigidity is formed. In this way, the front battery cross member lower and the rear battery cross member lower are fixed to a pair of side members through the battery cross member uppers.
US09034501B2 Electric storage unit
An electric power storage unit includes plural storage element blocks, an external bus bar for electrically connecting the storage element blocks, a base made of metal for fixing the storage element blocks, and a cover fixed to the base for accommodating the storage element blocks. Each of the storage element blocks includes plural electric power storage elements connected electrically to each other, and a case made of heat-conductive insulating resin for holding the electric power storage elements. This electric power storage unit reduces variation of cooling of the electric power storage elements, hence having high reliability.
US09034500B2 Laminated electrode-type battery, manufacturing method therefor, vehicle, and device
Provided are a laminated electrode-type battery having high joint strength and mechanical strength around a connecting portion between a positive-electrode current collector and a positive-electrode core member and around a connecting portion between a negative-electrode current collector and a negative-electrode core member, a manufacturing method therefor, a vehicle, and a device. The leading end of a positive-electrode core member and a positive-electrode current collector are joined by a connecting material. The melting point of the connecting material for positive-electrode is lower than that of the positive-electrode core member. Meanwhile, the leading end of a negative-electrode core member and a negative-electrode current collector are joined by a connecting material. The melting point of the connecting material for negative-electrode is lower than that of the negative-electrode core member.
US09034498B2 Secondary battery
A secondary battery including: an electrode assembly; a case for accommodating the electrode assembly and an electrolytic solution; and an identifying tape disposed in the case and that discolors when reacted with the electrolytic solution, wherein the identifying tape includes: a base film; an adhesive material disposed on one surface of the base film; and a discoloration material disposed on one surface of the base film.
US09034497B2 Vehicle battery pack container
A vehicle battery pack container is provided. The container includes a base member, a peripheral wall coupled to the base member, and a cover member coupled to the peripheral wall. The container further includes a venting device having a venting housing and a flow diverter member disposed within an interior region of the venting housing. The venting housing is coupled to the base member and is in fluid communication with an aperture in the base member. The venting housing has a tubular portion and a first end portion having a plurality of apertures extending therethrough. The flow diverter member has a central shaft, a first flow diverter plate, and a second flow diverter plate.
US09034495B2 Fuel cell system
A fuel cell system performs control such that when a power requirement for the fuel cell is lower than a predetermined value, a supply of a reaction gas to a fuel cell is stopped to keep an output voltage from the fuel cell equal to a high-potential avoidance voltage that is lower than an open end voltage. The fuel cell system further controls the output voltage from the fuel cell with the high-potential avoidance voltage set to be an upper limit when the power requirement for the fuel cell is equal to or higher than a predetermined value. By setting the upper limit of the output voltage of the fuel cell to be the high-potential avoidance voltage, which is lower than the open end voltage, the catalyst can be inhibited from being degraded by an increase in the output voltage from the fuel cell up to the open end voltage.
US09034493B2 Integrated battery and IC
Consistent with an example embodiment, there is an apparatus comprising a carrier, a laminated battery provided on a major surface of the carrier, and an integrated circuit. The laminated battery includes a bottom electrode layer, an electrolyte layer, and a top electrode layer. The integrated circuit is connected to the bottom electrode layer and the top electrode layer. The integrated circuit is surrounded by the laminated battery on the major surface of the carrier.
US09034488B2 Coated metallic products and methods for making the same
The present invention relates generally to jewelry articles comprising a substrate and a metallic, external coating.
US09034487B2 Light-emitting element material, light-emitting element, electronic device, and lighting device
A light-emitting element material including an ionic iridium complex in which a 2,6-bis(2-picolinyl)pyridine structure is coordinated to iridium is provided. Alternatively, a light-emitting element material including an ionic iridium complex represented by the following structural formula (1) is provided. In addition, a light-emitting element including the light-emitting element material is provided.
US09034486B2 Triazole derivative, heterocyclic compound, light-emitting element, light-emitting device, electronic device and lighting device
A triazole derivative represented by General Formula (G0) is provided. In the General formula (G0), A represents a substituted or unsubstituted carbazolyl group, a substituted or unsubstituted dibenzothiophenyl group, or a substituted or unsubstituted dibenzofuranyl group, E represents substituted or unsubstituted triazolo [4,3 f]phenanthridine or substituted or unsubstituted triazolo [3,4-α]isoquinoline, and Ar represents a substituted or unsubstituted arylene group having 6 to 13 carbon atoms. E-Ar-A  (G0)
US09034483B2 Phosphorescent materials
Phosphorescent materials and devices having high efficiency and stability, narrow spectrum, and improved processibility. In particular, iridium complexes containing acac-derived ligands with branched alkyl substituents with branching at a position further than the α position to the carbonyl group, were found to be suitable for use as emitters in OLED devices.
US09034480B2 Hot-dip Al—Zn coated steel sheet
There is provided a hot-dip Al—Zn coated steel sheet that has a steel sheet containing Si and Mn as a base steel sheet and has excellent coating appearance and corrosion resistance. The Al—Zn coating layer has an Al content in the range of 20% to 95% by mass. The Al—Zn coating layer has a Ca content in the range of 0.01% to 10% by mass. Alternatively, the Ca and Mg content is in the range of 0.01% to 10% by mass. A steel sheet surface layer within 100 μm from a surface of the base steel sheet directly under the Al—Zn coating layer contains 0.06 to 1.0 g/m2 per surface of an oxide of at least one selected from Fe, Si, Mn, Al, P, B, Nb, Ti, Cr, Mo, Cu, and Ni in total.
US09034478B2 Method for making a sheet of degradable paper, use of said sheet for making a mandrel defining a roll carrier, degradable paper sheet, and mandrel including at least one of said sheets
A method for making a water-degradable paper sheet involves the following: providing at least one strip of a water-soluble binding material in the form of a dry film; providing at least two strips each made of at least one ply of cellulose wadding; placing the strip of water-soluble binding material between the two strips of cellulose wadding; humidifying, assembling and pressing the three strips; and drying the complex strip thus obtained. The sheet thus obtained can be used for making a roll carrier mandrel by helically winding one or more strips from the sheet about a cylinder. Articles produced from the sheet can particularly be used in the field of products for sanitary or domestic use.
US09034473B2 Method for passivating a metallic surface with a basic composition
A method for passivating a metallic surface, by treating the surface with a basic aqueous composition comprising one polymer comprising acidic groups, a cationic crosslinker and a volatile basic compound, allows a durable passivation of fragile metal surfaces.
US09034471B2 Powder coating compositions and a method for coating a substrate, such as a thermally sensitive substrate
The invention relates to a powder resin with amp from 60 to 110° C., and a particle size from 10 to 250 μm, which comprises the reaction product of a reactive composition comprising: a) an isocyanate component comprising a polyisocyanate with functionality of at least 2, b) an alcoholic component, comprising: b1) at least one polyol with OH functionality from 2 to 4, b2) a monoalcohol component comprising: b2.1) a monoalcohol, bearing an ethylenic unsaturation b2.2) a saturated alcohol selected from the group of fatty alcohols, b2.3) optionally, an additional saturated monoalcohol from non fatty monoalcohols the molar ratios of OH functional groups, of the said alcoholic components b2.2) (possibly b2.3)) and b2.1) being defined so that the OH molar ratio of b2.2)/b2.1) or of [b2.2)+b2.3)]/b2.1) ranges from higher than 0.25 to 2, with the proviso that: the resulting said powder resin does bear at least one urethane unit with branched structure resulting from the reaction of an isocyanate component a) with a polyol component b), with said component a) having an average functionality higher than 2 or otherwise (if not higher than 2) the said component b1) having an average functionality higher than 2, with the resulting resin having no any crosslinked structure and being soluble in an organic solvent. The invention does also relate to a powder coating composition comprising the said resin and the resulting coatings and coated substrates for protective or decorative uses.
US09034470B2 Resin composition, multi-layered film and photovoltaic module including the same
A resin composition, a multi-layered film, a backsheet for photovoltaic modules, a method thereof, and a photovoltaic module are provided. The multi-layered film including a coating layer including a fluorine-based polymer has an excellent durability and weather resistance, and also exhibits high interfacial adhesive strength to a substrate since the multi-layered film is formed by coating a cured product of the resin composition including the fluorine-based polymer, an acrylic polymer including a thermosetting functional group, and a heat-curing agent on the substrate. In addition, drying can be performed at a low temperature during the manufacture of the multi-layered film so that the manufacturing costs can be decreased, productivity can be increased, and the deterioration of the product due to heat modification, heat shock, and the like, can be prevented. The multi-layered film can be effectively used as a backsheet for various photovoltaic modules.
US09034466B2 Sliding member
Slide member is provided with an Cu-based bearing alloy layer including hard particles, and DLC layer laminated over Cu-based bearing alloy layer. At least some of the hard particles included in Cu-based bearing alloy layer are exposed on DLC layer side surface.
US09034465B2 Thermally insulative attachment
A thermally insulative component is a thermal barrier panel attached to a rigid structural member with means for attaching the insulative component to an external structure. The connection between the structural member and the thermal barrier panel is mechanically compliant to minimize intercomponent stress build up during operation. The thermal barrier panel is a fiber wrapped ceramic oxide foam insulating structure.
US09034464B2 Single layer film and hydrophilic material comprising the same
There is stably provided a hydrophilic cured product, such as a single-layer film, in which anionic hydrophilic groups are concentrated at a surface that is in contact with the air and which is excellent in transparency and adhesion to a substrate and tends to be rarely cracked. The hydrophilic cured product or single-layer film comprising a resin composition is produced by applying a mixture containing a polyvalent monomer (II) having two or more (meth) acryloyl groups and a compound (IV) having a specific group and a sulfonic acid group to a substrate or the like, drying the mixture if necessary, and then performing polymerization.
US09034458B2 Edge-protected product and finishing method
An edge-protected product and finishing method therefor. The product comprises a first we and a second web bonded intermittently to the peripheral regions of a major surface of the sheet material to be protected. The bonded webs provide the desired level of protection to the peripheral regions and the edge surfaces of the sheet material. The intermittent bonding allows for the clean and convenient separation of the sheet material and the webs that a continuously bonded web would not be able to provide. Where laser cutting is used to separate the protected product, the edge-protected product with intermittent bonding areas allows for the separation without laser irradiation to the web material, thus no generation of toxic fume or charring due to oxidation, melting and/or disintegration of the web material caused by laser heating. The invention is particularly useful for protecting thin glass sheets, especially those in the form of a spool.
US09034452B2 Mold-in touch fastening product
A male touch fastener strip includes an elongated base and a field of male fastener elements. The male touch fastener strip also includes longitudinal barrier walls rising from the broad face of the base on either side of the field of male fastener elements, and a pair of segmented walls. Each segmented wall and its nearest longitudinal barrier wall define therebetween a foam relief space. Each segmented wall defines a flow gap for allowing the foam material to enter the foam relief space.
US09034451B2 Splicing adhesive tape comprising splittable connector elements
A splicing adhesive tape having a first carrier and a first splittable connector element having a left and a right boundary edge, wherein at least one of said two edges is not straight and comprises protrusions that are round at the locations thereof protruding out the farthest, and a second splittable connector element having a left and a right boundary edge, wherein at least one of said two edges is straight, wherein the first and the second splittable connector element are disposed adjacent to each other on the carrier.
US09034448B2 Methods for preparing modified release liners and modified adhesive articles
Adhesive articles are prepared through the use of modified release liners. The modified release liners include a fracturable layer and a release surface partially covering the fracturable layer. The modified release liners may be prepared by selective coating of a release material onto the fracturable layer or by selective treatment of a release surface to expose portions of the fracturable layer. Upon removal of an adhesive layer adhered to the modified release liner, portions of the fracturable layer of the release liner adhere to the adhesive layer to form a modified adhesive layer.
US09034444B2 Paper and cardboard packaging with barrier coating of a polymer mixture
Paper or cardboard packaging produced from recycled paper contaminated by mineral oil, where the packaging includes a barrier layer obtained by applying an aqueous polymeric dispersion containing a mixture of at least two polymers A and B. Polymer A is obtained by emulsion polymerization of C1-C4 alkyl(meth)acrylates, acid monomers, e.g., acrylic acid or methacrylic acid, 0-20 wt % of acrylonitrile and 0-10 wt % of further monomers, where the glass transition temperature of copolymer A is greater than +45° C. and the glass transition temperature of polymer B is less than +10° C. The mean value calculated from the glass transition temperatures of the individual polymers is +10 to +45° C. The barrier layer may be situated on one of the surfaces of the packaging or form one of multiple layers of a multilayered packaging coating or be situated as a coating on one side of an inner bag situated within the packaging.
US09034441B2 Impact energy attenuation system
A new and novel impact energy attenuation material, impact energy attenuation module employing the material and a fit system for optimizing the performance thereof is provided. Non-linear energy attenuating material consisting of a plurality of loose particles is employed for impact energy dissipation. The loose particles are preferably spherical elastomeric balls. An impact energy attenuation module includes a container that holds the loose particles. The impact energy attenuation module can be provided in a wide range of sizes and shapes and the loose particles can be provided in different materials, sizes, density, compaction and hardness to suit with the application at hand. A matrix of impact energy attenuation module are provided about the surface of a shell to provide the required impact energy attenuation. The material, impact energy attenuation module and system of the present invention are well suited for protection of body parts and other cushioning and protection needs.
US09034427B2 Method of forming opaque layer, recording process, ink set, ink cartridge, and recording apparatus
A method of forming an opaque layer includes forming a first layer by discharging droplets of an ink composition containing a metallic pigment on a record medium by an ink-jet recording process and forming a second layer by discharging droplets of an ink composition containing a white pigment on the record medium by an ink-jet recording process. The opaque layer is formed on the record medium on the side where the first layer and the second layer are formed in a region where the first layer and the second layer overlap each other.
US09034426B2 Nanostructured thermoplastic polyimide films
Structured films containing multi-walled carbon nanotubes (“MWCNTs”) have enhanced mechanical performance in terms of strength, fracture resistance, and creep recovery of polyimide (“PI”) films. Preferably, the loadings of MWCNTs can be in the range of 0.1 wt % to 0.5 wt %. The strength of the new PI films dried at 60° C. increased by 55% and 72% for 0.1 wt % MWCNT and 0.5 wt % MWCNT loadings, respectively, while the fracture resistance increased by 23% for the 0.1 wt % MWCNTs and then decreases at a loading of 0.5 wt % MWCNTs. The films can be advantageously be created by managing a corresponding shift in the annealing temperature at which the maximum strength occurs as the MWCNT loadings increase.
US09034425B2 Method and apparatus for applying adhesive on an elastic strand in a personal disposable hygiene product
A method of dispensing adhesive onto a stretched elastic strand includes applying a first volume of adhesive onto a first portion of the elastic strand, applying a second volume of adhesive onto a second portion of the elastic strand, and applying a third volume of adhesive onto a third portion of the elastic strand. The second volume is less than the first and third volumes. When the elastic strand is adhered to a substrate to form a personal disposable hygiene product, the first and third portions of the elastic strand define opposing ends of the elastic strand, which are adhered with a larger amount of adhesive to resist creep at the opposing ends. The reduction of adhesive in the second or central portion between the opposing ends significantly reduces the adhesive add on in the personal disposable hygiene product.
US09034422B2 Method of doping surfaces
Disclosed herein are methods of treating an article surface. The method comprises removing a metal oxide surface from the metal substrate to expose a metal surface; and delivering particles comprising a dopant from at least one fluid jet to the metal surface to impregnate the surface of the article with the dopant. The method also comprises delivering substantially simultaneously a first set of particles comprising a dopant and a second set of particles comprising an abrasive from at least one fluid jet to a surface of an article to impregnate the surface of the article with the dopant.
US09034421B2 Method of forming electrodes comprising sulfur and porous material comprising carbon
The present invention relates to electrochemical cells, electrodes, and related methods. In some embodiments, a removable filler material may be employed during fabrication of an electrochemical cell, or component thereof, to produce electrochemical devices having improved cell performance and rate capability. Electrochemical cells may exhibit enhanced utilization of electroactive species and/or increased accessibility of electroactive species within the electrochemical cell during operation. In some cases, the invention may provide electrodes which advantageously possess both high loading of an electroactive species (e.g., greater than 1.5 mg/cm2), while also maintaining the stability and good mechanical properties of the electrode.
US09034420B2 Touch screen substrate and method of manufacturing a touch screen substrate
A method of manufacturing a touch screen substrate includes forming a sensing electrode on a substrate, spraying a first ink and a second ink on the substrate including the sensing electrode, where the first ink includes a first solvent and insulation balls having a first diameter and the second ink includes a second solvent and conductive balls having a second diameter smaller than the first diameter, and hardening the first and second inks on the substrate, to fix the insulation balls on the substrate and the conductive balls on the sensing electrode formed on the substrate.
US09034416B2 Method of fabricating organic electroluminescent display device
A method for fabricating an organic electroluminescent display device usable for large-area applications includes: preparing a first substrate; preparing a transfer plate having at least one transfer pattern; forming a first electrode on the first substrate; forming organic light emitting patterns on the at least one transfer pattern on the transfer plate within a region; and bonding the first substrate to the transfer plate, and after the bonding, transferring the organic light emitting patterns from the transfer plate onto the first substrate using a pressure difference between an area within the region and an area outside of the region.
US09034409B2 Flavoring substance-included cellulose
The present invention concerns a flavoring substance-included cellulose, comprising or consisting of cellulose and flavoring substances included in the cellulose, methods for producing such flavoring substance-included celluloses, and mixtures comprising flavoring substance according to the invention.
US09034408B2 Packaging
Atmosphere control members (ACMs) are used in various ways. In one aspect, at least one of the atmospheres in contact with the ACM is cause to flow over the surface of the ACM. In another aspect, the ACM is an internal ACM which does not form part of the exterior surface of a container. In another aspect, the ACM forms part of a reusable module. In another aspect, a plurality of sealed containers, each including an ACM, are stored in an outer container also including an ACM. FIGS. 3-5 illustrate a shipping container (11) comprising an internal ACM (3) having one surface which is exposed to the packaging atmosphere within the shipping container and an opposite surface which is part of a closed chamber (2) to which gases can be supplied in a controlled fashion.
US09034407B2 Method and system for treating food items with an additive and solid carbon dioxide
Embodiments of the invention generally provide methods and systems that distribute an additive in solid carbon dioxide in an interior of food processing equipment. The additive may be injected into a flow of liquid carbon dioxide upstream of an expander at or adjacent to the interior. Injection of the additive into the interior may be alternated with directing a flow of expanded carbon dioxide into the interior. In some embodiments, the freezing point of the additive with or without a diluent composition and/or additive(s) is lower than a temperature of the liquid carbon dioxide.
US09034395B2 Processes and apparatus for extraction of active substances and enriched extracts from natural products
Processes for preparing extracts of natural products such as plant material, and for preparing purified extracts from crude extracts of natural products, by extraction with hot gas. Apparatus suitable for use in preparing extracts of natural products are also described.
US09034393B2 Bioactive acid agrichemical compositions and use thereof
Bioactive agrichemical concentrates and compositions having improved bioactivity comprising combinations of acid solutions and conventional bioactive agrichemical actives or formulations.
US09034391B2 Compositions with enhanced bioavailability and fast acting inhibitor or gastric acid secretion
The present invention relates to the use of pharmaceutically acceptable zinc salts, preferably water soluble zinc salts alone or optionally, in combination with one or more of a protein pump inhibitor (PPI), H2 blocker, anti-H. pylori antibiotic/antimicrobial, cytoprotective agent or a combination agent as otherwise described herein for providing fast action with optional long duration effect in reducing gastric acid secretion, raising the pH of the stomach during resting phase as well as decreasing the duration of stomach acid release during a secretagogue phase and for treating conditions including gastroesophageal reflux disease (GERD), non-erosive reflux disease (NERD), Zollinger-Ellison syndrome (ZE disease), ulcer disease, and gastric cancer, as well as preventing or reducing the likelihood of ulcer disease. In addition, the present methods are useful for treating patients who are non-responsive to proton pump inhibitors (PPI) and as an alternative to traditional therapies or conditions which are caused by rapid and complete inhibition of secretagogue induced acid secretion. The present invention also relates to the use of one or more water soluble zinc salts, administered in combination with a therapeutic compound or agent (second therapeutic agent) which may be delivered orally with enhanced bioavailability (compared to compounds which are administered in the absence of water soluble zinc salts) or other favorable benefits. In addition, therapeutic agents which exhibit sensitivity to low pH may be advantageously orally administered in combination with an effective amount of at least one water soluble zinc salt. Compositions according to the present invention exhibit greater bioavailability of the active agent when formulated in combination with a water soluble zinc salt in oral dosage form than when administered with the water soluble zinc salt.
US09034388B2 Bioeffective krill oil compositions
This invention discloses new krill oil compositions characterized by having high amounts of phospholipids, astaxanthin esters and/or omega-3 contents. The krill oils are obtained from krill meal using supercritical fluid extraction in a two stage process. Stage 1 removes the neutral lipid by extracting with neat supercritical CO2 or CO2 plus approximately 5% of a co-solvent. Stage 2 extracts the actual krill oils by using supercritical CO2 in combination with approximately 20% ethanol. The krill oil materials obtained are compared with commercially available krill oil and found to be more bioeffective in a number of areas such as anti-inflammation, anti-oxidant effects, improving insulin resistances and improving blood lipid profile.
US09034384B2 Polyurea microcapsules
The present invention relates to polyurea core-shell microcapsules having a polyurea shell comprising the reaction product of a polyisocyanate with guanazole and an amino acid. The invention concerns the capsules themselves as well as perfuming compositions and perfumed articles containing them and a process for producing them.
US09034381B2 Process to control particle size
A multi-stage process to control the particle size of a pharmaceutical substance comprising the steps of: passing the pharmaceutical substance through a first stage of a particle size reduction process with a first set of particle size control parameters to obtain a feedstock of reduced median particle size and lesser distribution of median particle size for a second stage of a particle size reduction process; passing the feedstock, through a second stage of a particle size reduction process with a second set of particle size control parameters; optionally, using the product of the second stage or subsequent stages as a feedstock in further stages of a multi-stage particle size reduction process with a set of particle size control parameters for each stage; and collecting a pharmaceutical substance with a median particle size greater than 10 μm and with a narrow, reproducible distribution of median particle sizes.
US09034379B2 Processing of acylchitosan hydrogels
An article containing N-acylchitosan is manufactured by a process comprising the steps of providing a mixture containing chitosan and/or N-acylchitosan, and extruding the mixture to form an N-acylchitosan hydrogel. Alternatively, the process comprising the steps of providing a chitosan and/or N-acylchitosan hydrogel, and extruding the hydrogel. An article with a memorized shape is formed by fixing the N-acylchitosan hydrogel in a desired shape, and at least partially drying the fixed hydrogel. A patient is treated by injecting the N-acylchitosan hydrogel.
US09034374B2 Acoustically sensitive drug delivery particles comprising non-lamellar forming phosphatidylethanolamine
Novel acoustically sensitive drug carrying particles comprising non-lamellar forming lipids are disclosed, as well as uses and methods thereof. The drug carrying particles accumulate in the diseased target tissue and efficiently release their pay-load upon exposure to acoustic energy.
US09034369B2 Article comprising calcium for reducing the production of TSST-1
Articles comprising one or more calcium salts are provided. The articles can contain one or more calcium salts in an amount effective to reduce the production of TSST-1 by at least about 50% when measured by the Shake Flask Method. In certain embodiments, the one or more calcium salts can be substantially non-lethal to Staphylococcus aureus when measured by the Shake Flask Method, and/or to Lactobacillus crispatus, Lactobacillus gasseri, and/or Lactobacillus iners when measured by the Maximum Tolerated Dose Test.
US09034368B2 Method of topically applying glycopyrrolate solution using absorbent pad to reduce sweating
This invention relates to a convenient and safe product and method of applying glycopyrrolate topically in order to reduce excessive sweating in localized areas for those who suffer from this condition. This invention also relates to combining oral and topical delivery of glycopyrrolate to reduce excessive sweating and minimize side effects. This invention also relates to a convenient and safe product and method of applying glycopyrrolate topically to areas of compensatory sweating after endoscopic thoracic sympathectomy.
US09034366B2 Composition and method to alleviate joint pain using a mixture of fish oil and fish oil derived, choline based, phospholipid bound fatty acid mixture including polyunsaturated EPA and DHA
Beneficial and synergistic effects for alleviating joint pain and symptoms of osteoarthritis and/or rheumatoid arthritis have been found using a mixture of fish oil and fish oil derived, choline based, phospholipid bound fatty acid mixture including polyunsaturated EPA and DHA either alone or in combination with other active constituents, including astaxanthin and polymeric hyaluronic acid or sodium hyaluronate (hyaluronan) in an oral dosage form.
US09034364B2 Cell-adhesive, enzymatically crosslinked flavonoid hydrogels and methods for making same
There are provided methods for producing a hydrogel that is capable of adhesion of cells and which comprises enzymatically cross-linked conjugates of a hydrogel forming agent and a flavonoid, formed from a reaction using peroxide and peroxidase. Hydrogels produced by such methods and methods of using the hydrogels are also provided.
US09034363B2 Drug-eluting insertable medical device for treating acute myocardial infarction, thrombus containing lesions and saphenous-vein graft lesions
A method for delivering at least one drug at a target site in a blood vessel for treating at least one of an acute myocardial infarction, a thrombus containing lesion and a saphenous-vein graft lesion is disclosed. The method includes delivering nano-carriers at the target site. The nano-carriers include one or more drugs encapsulated with a first biological agent. The nano-carriers further include a second biological agent in contact with one or more of the first biological agent and the one or more drugs. The first biological agent and the second biological agent have a first dissolution rate and a second dissolution rate respectively. The first dissolution rate is different from the second dissolution rate. The one or more drugs are released at the target site from the nano-carriers at a first release rate and a second release rate in response to dissolution of the first biological agent and the second biological agent, respectively.
US09034357B2 Anti-adhesion barrier
The present disclosure relates to medical devices comprising at least a first film layer and at least a second gel layer and to methods for preparing such devices.
US09034356B2 Porous osteoimplant
The invention is directed toward porous composites for application to a bone defect site to promote new bone growth. The inventive porous composites comprise a biocompatible polymer and a plurality of particles of bone-derived material, inorganic material, bone substitute material or composite material. In certain embodiments, the porous composites are prepared using a method that includes a supercritical fluid (e.g., supercritical carbon dioxide) treatment. The invention also discloses methods of using these composites as bone void fillers.
US09034350B2 Cleansing composition
A post-foaming cleansing composition comprises at least one anionic surfactant, at least one non-ionic gelling agent and at least one post-foaming agent. The ratio of anionic surfactant:non-ionic gelling agent is 4:1 or greater such that during manufacture a gel structure is formed. The gel structure remains substantially unchanged for at least 4 minutes after the addition of the said post-foaming agent to the remainder of the composition.
US09034346B2 Implantable or insertable medical device resistant to microbial growth and biofilm formation
Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents.
US09034345B2 GNA1870-based vesicle vaccines for broad spectrum protection against diseases caused by Neisseria meningitidis
The present invention generally provides methods and compositions for eliciting an immune response against Neisseria spp. bacteria in a subject, particularly against a Neisseria meningitidis serogroup B strain.
US09034343B2 Attenuated human parainfluenza virus, methods and uses thereof
The invention provides self replicating infectious recombinant paramyxoviruses. The recombinant paramyxovirus preferably have one or more attenuating mutations. In some embodiments, the recombinant paramyxovirus has a separate variant polynucleotide encoding a P protein and a separate monocistronic polynucleotide encoding a V protein. In some embodiments, recombinant paramyxovirus have at least one temperature sensitive mutation and one non-temperature sensitive mutation. Also provided are compositions and methods for using the recombinant paramyxoviruses as described herein.
US09034327B2 G protein coupled receptor protein and use thereof
Disclosed are novel GPCR (G Protein Coupled Receptor) proteins and genes encoding the same. Also provided is the use of the proteins and the genes. Particularly, contemplated are a novel GPCR (G Protein Coupled Receptor) polypeptide, a polynucleotide coding for the same, a recombinant vector carrying the polynucleotide or a fragment thereof, host cells transformed with the vector, a transgenic animal infected with the vector. Also, a composition for detecting a cancer marker, comprising an agent capable of measuring the expression level of mRNA or protein of the GPCR polynucleotide, a kit for the diagnosis of cancer, comprising the composition, and a method for detecting the GPCR polypeptide and a gene encoding the polypeptide are provided. Further, a composition for the treatment and prevention of cancer, comprising an oligonucleotide inhibiting the expression of a gene encoding the GPCR polypeptide or an antibody against the GPCR protein, and a method for screening a modulator of the GPCR protein or a cancer therapeutic agent are provided.
US09034324B2 Anti-BCMA antibodies
This invention provides antibodies that recognize the B Cell Maturation Antigen (BCMA) and that bind naïve B cells, plasma cells, and/or memory B cells. The invention further provides methods for depleting naïve B cells, plasma cells, and memory B cells, and for treating B cell-related disorders, including lymphomas and autoimmune diseases.
US09034318B2 Chemically modified cystathionine beta-synthase enzyme for treatment of homocystinuria
The invention provides reagents and methods for enzyme replacement therapy using chemically modified species of human cystathionine β-synthase (CBS) to treat homocystinuria and other related diseases and disorders.
US09034311B2 Pyridin-2(1 H)-one derivatives as JAK inhibitors
New pyridin-2(1H)-one derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).
US09034310B2 Interferon-statin combination cancer therapy
A method for pharmacological treatment of cancers and other diseases is presented which includes the novel combination of a statin (Hmg-CoA reductase inhibitor, such as lovastatin, simvastatin, atorvastatin, cerivastatin, fluvastatin, pravastatin, or newer agents), with an interferon (such as interferon alfa-2b or others) and also including concurrent administration of selenium and calcium. The method disclosed in this invention is useful because it can prove more effective than previously known therapies for certain diseases and because its use may be more tolerable, less disfiguring, and less expensive than other methods. The method here disclosed can be readily reproduced by any person skilled in the art of treating disease.
US09034304B2 Sunscreen composition
The invention relates to a high SPF sunscreen composition. There is a problem of achieving high SPF while keeping the total amount of sunscreens in the compositions relatively low. It is desirable, that the enhanced SPF benefit could be achieved through synergistic interaction of commonly used ingredients, thereby the present applicants have been working on solving this problem and have surprisingly found that cosmetic compositions comprising dibenzoylmethane or its derivative in combination with an oil soluble UV-B sunscreen when incorporated in a sunscreen composition along with a non-ionic surfactant of a select class meeting certain HLB requirements, provide the enhanced SPF benefits when applied on the substrate of interest.
US09034302B2 Mineral sunscreen composition and process for protecting skin from photodamage and aging
The present invention is directed to a composition and method for protecting a keratinous substrate from harmful UV rays by applying onto the substrate a composition containing: (a) at least one oil phase thickening agent chosen from an activated clay; (b) at least one substantially solid form dispersing aid; (c) at least one non-volatile solvent; (d) at least one inorganic sunscreen active; (e) at least one emulsifier; (f) at least one volatile solvent; and (g) water, and wherein (a) and (b) are present in the composition in a ratio by weight ranging from greater than 1:4 to less than 1:10.
US09034301B2 Remineralization promoter and composition for oral cavity
It is intended to provide a remineralization promoter for tooth enamel and a composition for an oral cavity, which can highly effectively promote the remineralization of tooth enamel and strongly inhibit dental caries. The remineralization promoter for tooth enamel and the composition for an oral cavity are characterized by containing amorphous hydroxyapatite and/or amorphized hydroxyapatite showing two peaks at 2θ=31 to 35° in X-ray diffraction. The amorphized hydroxyapatite is obtained by reacting calcium salt with phosphate in an aqueous solution and drying the reaction solution at a temperature of 10 to 70° C.
US09034300B2 Composition and method for medical imaging of body cavities
A foamed aqueous image enhancing composition containing cellulose and/or cellulose derivative(s), has a pH between 5.5 and 7, wherein the viscosity of the composition is less than 1800 mPa·sec, and wherein a gas is maintained in the composition for at least 1 minute after preparation. The combination of low viscosity and foam stability makes the composition particularly suitable in patency tests and fallopian tube sterilization checks.
US09034299B2 ATF4 inhibitors and their use for neural protection, repair, regeneration, and plasticity
In one aspect, the invention relates to a method for identifying a drug candidate with activity as a neuroprotective agent. The method includes determining whether a compound reduces ATF4 activity; and identifying the compound that reduces ATF4 activity as a drug candidate.
US09034298B2 Chelating amphiphilic polymers
Described are amphiphilic polymers that are provided with chelating moieties. The amphiphilic polymers are block copolymers comprising a hydrophilic block and a hydrophobic block, with the chelating moieties linked to the end-group of the hydrophilic block. The disclosed polymers are capable of self-assembly into structures such as micelles and polymersomes. With suitable metals present in the form of coordination complexes with 5 the chelating moieties, the chelating amphiphilic polymers of the invention are suitable for use in various imaging techniques requiring metal labeling, such as MRI (T 1/T 2 weighted contrast agents or CEST contrast agents) SPECT, PET or Spectral CT.
US09034297B2 Production of nano-structures
A process for the production of nano-structures is presented, involving providing a graphite flake comprising graphene layers; intercalating the graphite flake to form a graphite intercalation compound exhibiting Stage I, II or III intercalation; and exfoliating the graphite intercalation compound by exposing it to a temperature between about 1600° C. and about 2400° C. such that a plurality of individual graphene layers are separated from the graphite intercalation compound.
US09034293B2 Process for preparing hydrocyanic acid by catalytic dehydration of gaseous formamide—direct heating
Process for preparing hydrocyanic acid by catalytic dehydration of gaseous formamide, wherein the dehydration of formamide is coupled with an exothermic reaction by the reactor used in the dehydration comprising two separate fluid paths which are separated by a common reactor wall, with one fluid path being provided for the dehydration of formamide and the second fluid path being provided for the exothermic reaction.
US09034289B1 Method and apparatus for prolonging the service life of a collective protection filter using a guard bed
A method for extending the service life of a Collective Protection (CP) filter includes: providing at least one CP filter comprising a filter bed; and passing an airstream through a guard bed configured to protect the filter bed by removing one or more of airborne contaminants and battlefield contaminants. An apparatus for extending the service life of a CP filter includes: a CP filter comprising a filter bed; and a guard bed configured to protect the filter bed by removing one or more of airborne contaminants and battlefield contaminants.
US09034288B2 Alkanolamine CO2 scrubbing process
A CO2 amine scrubbing process uses an absorbent mixture consisting of an alkanolamine CO2 sorbent in combination with a non-nucleophilic base. The alkanolamine has oxygen and nitrogen sites capable of nucleophilic attack at the CO2 carbon atom. The nucleophilic addition is promoted in the presence of the non-nucleophilic, relatively stronger base, acting as a proton acceptor. The non-nucleophilic base promoter, which may also act as a solvent for the alkanolamine, can promote reaction with the CO2 at each of the reactive hydroxyl and nucleophilic amine group(s) of the alkanolamines. In the case of primary amino alkanolamines the CO2 may be taken up by a double carboxylation reaction in which two moles of CO2 are taken up by the reacting primary amine groups.
US09034283B2 Hybrid process using ion exchange resins in the selective recovery of nickel and cobalt from leaching effluents
The present invention is directed to a hybrid process using ion exchange resins in the selective recovery of nickel and cobalt of leaching effluents that is comprised of the steps of processing (1) the laterite ore (M), which is then treated through leaching (2) (either atmospheric or under pressure), considering solutions from the solid-liquid separation step of existing plants already in operation (2) as well, in a way that the downstream process comprises an ion exchange hybrid circuit, wherein the first ion exchange step (3) with resins (Re) exhibits specific selectivity conditions for the removal of iron, aluminum and copper and an increased pH, and the second ion exchange step (4) allows the removal of nickel and cobalt.
US09034282B2 Catalytic reactor including one cellular area having controlled macroporosity and a controlled microstructure and one area having a standard microstructure
The invention relates to a catalytic reactor including: at least one first architecture/microstructure including a ceramic and/or metal cellular architecture having a pore size of 2 to 80 ppi and a macroporosity of more than 85%, and a microstructure having a grain size of 100 nm to 5 microns, and skeleton densification of more than 95%, and a catalytic layer; and at least one second architecture/microstructure including a spherical or cylindrical architecture having a pore size of 0.1 to 100 μm and a macroporosity of less than 60%, and a microstructure having a grain size of 20 nm to 10 μm and a skeleton densification of 20% to 90%, and a catalytic layer; the first and second architecture/microstructure being stacked inside said reactor.
US09034281B2 Device for separating a membrane from a support
A device (1, 100) for separating a membrane (81, 91) to analyze from a support (83, 93), the membrane being mounted in a frame (82, 92), itself mounted on a support, having a body (10) comprising a longitudinal recess (11, 110, 120) for translational reception of the assembly constituted by the frame mounted on the support, the recess having a first end (12) and a second end (13) and longitudinal sides (14A, 14B, 111, 121) facing each other between said two ends, the device having bearing means (30, 112, 122) for a first member of the frame/support group between the first and the second end of the recess, which are adapted to serve as a bearing for the first member of the frame/support group once the assembly is disposed in the recess, each of the sides having a ramp (15A, 15B, 112, 122) adapted to engage a gripping member (84, 73) of the second member of the frame/support group when the assembly is translationally moved from the first to the second end, said ramps being adapted to separate the support from the frame during said translational movement by bearing on said gripping member of the second member of the frame/support group, the first member of the frame/support group then bearing on the bearing means, such that the frame and the support are separated once the translational movement has arrived at the second end.
US09034279B2 Bio-chip
There is provided a bio-chip, including a fixing plate having a plurality of guide grooves formed in one surface thereof, a first substrate having a plurality of support plates inserted into the guide grooves, and a plurality of pillars protruded from one surface of the respective support plates, and having a biomaterial disposed thereon.
US09034276B2 Oestrus detector
An oestrus detector 100 includes a reservoir portion 135 which contains a colored liquid. The detector 100 further includes a generally planar portion 110 that is attached to and sealed from the reservoir portion 135, except for an open or closed passage 111 in a seal line separating the reservoir portion 135 and the generally planar portion 110. In use the liquid is squeezed from the reservoir portion 135, through the passage 111, and into the generally planar portion 110, when the reservoir portion 135 receives pressure.
US09034275B2 Chemical sensor using metal nano-particles and method for manufacturing chemical sensor using metal nano-particles
A chemical sensor using metal nano-particles and a method for manufacturing a chemical sensor using metal nano-particles are provided. The chemical sensor includes: metal nano-particles; single-ligand organic molecules (or a single molecule) that binds to the metal nano-particles by using a metal bonding functional group; a substrate bonding functional group formed at the metal nano-particles and the single-ligand organic molecules as bound to each other; a substrate; electrodes formed on the substrate and having an interdigitate (IDT) structure; and a substrate functional group formed on the substrate and positioned between the electrodes, wherein the substrate bonding functional group and the substrate functional group are covalently bonded.
US09034274B2 Vehicular air cleaner
The present invention relates to a vehicular air cleaner. A DOR (Direct Ozone Reduction) system for suppressing deterioration of a purifying function of an ozone purifying material is provided. Active oxygen is produced by an ozone purifying function of activated carbon. The probability that the active oxygen contacts with a fin of a radiator on a rear surface side is higher than that on a front surface side of the radiator. Accordingly, the activated carbon on the rear surface side of the radiator is easily oxidized as compared with the activated carbon on the front surface side. Therefore, in the fin, a coating amount of the activated carbon on the front surface side of the radiator is adjusted to be larger than a coating amount of the activated carbon on the rear surface side. Thus, the probability that the active oxygen contacts with the activated carbon can be reduced.
US09034272B2 Apparatus for synthesizing oligonucleotides and methods of use
The present invention relates to apparatus and methods for synthesizing oligonucleotides wherein a reaction zone has a variable volume based on the position of a piston, and the piston is adjusted to control the amount of headspace above solid support in the reaction zone. Methods and apparatus that limit the size or existence of the headspace are described.
US09034269B2 Diesel oxidation catalyst comprising palladium, gold and ceria
The present invention relates to a diesel oxidation catalyst comprising a carrier substrate, and a first washcoat layer disposed on the substrate, the first washcoat layer comprising palladium supported on a support material comprising a metal oxide, gold supported on a support material comprising a metal oxide, and a ceria comprising compound, as well as a process for the preparation of such catalyst.
US09034263B2 Assay plates, reader systems and methods for luminescence test measurements
Luminescence test measurements are conducted using an assay module having integrated electrodes with a reader apparatus adapted to receive assay modules, induce luminescence, preferably electrode induced luminescence, in the wells or assay regions of the assay modules and measure the induced luminescence.
US09034260B2 Apparatus and method for selecting particles
The invention provides a device and a method for flow cytometric fractionation of particles contained in a fluid stream, wherein sections of the fluid stream, especially droplets if the fluid stream is a droplet stream, are irradiated with a laser. The laser disposed for the irradiation of the sections of the fluid stream can have a wavelength which is absorbed by the fluid and can have a sufficient radiation duration and radiation intensity to deflect sections of the fluid stream.
US09034259B2 Flow cytometer and flow cytometry
One embodiment of the present invention is to provide a system for sorting cell particles in a liquid flow, which comprises a flow-defining block including a flow chamber receiving a sample conduit and a flow cell having a flow channel. The system also comprises a strobe block including a imaging device for taking an image of a jet flow ejected from the flow-defining block and a plurality of droplets in a given image area. The flow-defining block and the strobe block are detachably connected each other. Further the strobe block includes a nozzle plate having a nozzle channel between a receiving end and a nozzle. The flow-defining block includes a discharge end opposite to the receiving end and a channel enlarged portion of which cross section taken along a predetermined plane perpendicular to a flow direction has an area increasing towards the discharge end. The discharge end and the receiving end have substantially the same open distance in the predetermined plane perpendicular to the flow direction.
US09034257B2 High throughput flow cytometry system and method
The invention provides systems, compositions, kits and methods for automated processing of biological samples and analysis using a flow cytometer.
US09034256B2 Method and apparatus for preparing a solution of shear sensitive material
The invention provides a novel apparatus and method for preparing a solution of a shear sensitive material.
US09034255B2 Purified hydrogen peroxide gas microbial control methods and devices
The present invention relates to methods and devices for providing microbial control and/or disinfection/remediation of an environment. The methods generally comprise: generating a Purified Hydrogen Peroxide Gas (PHPG) that is substantially free of, e.g., hydration, ozone, plasma species, and/or organic species; and directing the gas comprising primarily PHPG into the environment such that the PHPG acts to provide microbial control and/or disinfection/remediation in the environment, preferably both on surfaces and in the air.
US09034249B2 Automated sterilization process integrated with a blow fill seal machine
A process and system for sterilization of a product pathway of a blow-fill-seal machine. The process comprises steps of: (1) isolating a holding tank from the product pathway; (2) supplying a sterilizing agent to the product pathway of the BFS machine when the holding tank is isolated; (3) stopping the supply of sterilizing agent to the product pathway when a threshold is reached; and (4) supplying filtered compressed air to the product pathway when the supply of sterilizing agent is stopped. The process is preferably executed automatically without human intervention once initiated. Also described is a system for carrying out the process including a processor, valves and temperature and/or pressure sensors which provide information to the processor to determine when to open and close the valves to supply sterilizing agent and/or compressed air to the product pathway or holding tank.
US09034245B2 Method for forming a tubular medical device
A method and process for at least partially forming a medical device that is at least partially formed of a metal alloy which improves the physical properties of the medical device.
US09034244B2 Gas-transfer foot
The present invention includes a molten metal pump and associated components that enable gas to be released into a stream of molten metal. The gas may be released into the molten metal stream (preferably into the bottom of the stream) flowing through a passage. Such a stream may be within the pump discharge and/or within a metal-transfer conduit extending from the pump discharge. The gas is released by using a gas-transfer foot that is positioned next to and is preferably attachable to the pump base or to the metal-transfer conduit. Preferably, the conduit (and/or discharge) in which the gas is released comprises two sections: a first section having a first cross-sectional area and a second section downstream of the first section and having a second cross-sectional area, wherein the second cross sectional area is larger than the first cross-sectional area. Preferably, the gas is released into or near the second section so that the gas is released into an area of relatively lower pressure.
US09034241B2 Handle for container, handle-equipped container, and method for manufacturing handle and container
The present invention provides a handle for a container, a handle-equipped container, and a method for manufacturing same. It is accordingly possible to provide a container that has a cross-sectional shape that is substantially quadrangular and allows for exceptional storability, has favorable blow-molding properties, presents none of a variety of anomalies in the container and the handle, and has adequate strength to withstand drop impact.
US09034238B2 System, method, and apparatus for solar heated manufacturing
A system for a thermal manufacturing system including a heliostat and a mold. The heliostat includes at least one reflecting surface, a steering mechanism and a controller. The steering mechanism is coupled to the at least one reflecting surface and capable of directing at least a first portion of the at least one reflecting surface toward a first one of multiple, selectable focal points. The mold is located in a second one of the selectable focal points. A manufacturing method is also disclosed.
US09034236B2 Substrate-based additive fabrication process
The invention relates to a substrate-based method for forming a three-dimensional object by additive fabrication by coating a liquid radiation curable resin comprising from 30 to 80 wt % of cationically curable compounds on a substrate, contacting the liquid radiation curable resin with a previously cured layer, selectively exposing the layer of liquid radiation curable layer to actinic radiation thereby forming a cured layer, separating the cured layer at the substrate, and repeating the steps a sufficient number of time in order to build up a three-dimensional object.
US09034231B2 Cup lid
A liquid container includes a brim forming a mouth opening into a product receiving chamber formed in a cup. A lid is coupled to the rim to close the mouth of the cup.
US09034230B2 Method for making an elastomeric apertured web
A method for making an elastomeric apertured web comprises providing a precursor web comprising a laminate which is subjected to incremental stretching to form an elastomeric precursor web. A forming apparatus is provided comprising a first member and a second member, wherein the first member comprises a mating member, and the second member comprises teeth which are joined to the second member. The elastomeric precursor web is moved through the forming apparatus, wherein apertures are formed in the elastomeric precursor web material as the teeth on the second member penetrate the mating member forming an elastomeric apertured web. The elastomeric apertured web exhibits a WVTR of at least about 1000 g/m2/day.
US09034225B2 Process for producing implants and components by directing shaping
The invention relates to a method for producing implants and components by direct shaping. The method includes the steps of producing a mold for the implants or components to be produced, making allowances for changes in geometry occurring during after-treatment after the implants or components are removed from the mold, and, providing partial areas of the mold with a structured surface for transferring this structure to the surfaces of the implants or components. In the method, raw material is introduced into the mold and, after remaining in the mold for a certain period of time, the hardened raw material is then removed from the mold to allow the implants or components to take on the structured surface of the mold as well as its geometry. The demolded implants or components are finally subjected to any after-treatment that may be necessary.
US09034223B2 Optical film and process for producing the same
An optical film of high planarity that even in the use of an optical film material containing a non-resinous additive in an amount of 5 mass % or more, would exhibit inexpensive satisfactory roll cleaning effects, and that would find application in, especially, various functional films such as a retardation film and a protective film for polarization plate for use in a liquid crystal display apparatus, etc.; and a process for producing the optical film. There is disclosed a process for producing an optical film according to a melting casting film forming method, including extruding a melt of resin blend containing a resin and 5 mass % or more of non-resinous additive through a casting die into a film form, wherein a first roller (5) for cooling has a temperature of the melting point of the additive to the glass transition temperature (Tg) of the resin blend. Preferably, the first roller (5) for cooling has a peripheral speed (S1) exhibiting a ratio between the same and the peripheral speed (S3) of a third roller (7) for cooling, S3/S1, of 1.001 to 1.05. Preferably, a filmlike molten blend is pressed against the first roller (5) for cooling at a linear pressure of 0.5 to 50 N/mm by means of a second roller (6) for pressure application.
US09034222B2 Method for producing photonic wire bonds
A method for making optical connections with optical waveguides includes mounting the optical waveguides or a device comprising the optical waveguides, on a component carrier. A partial region of the optical waveguides is embedded in a volume of resist material. Positions of the optical waveguides to be connected are detected with reference to a coordinate system using a measuring system. Favorable, three-dimensional geometries are determined for optical waveguide structures for connecting the optical waveguides to each other at predetermined connecting locations and the optical waveguide structure geometries are converted to a machine-readable dataset. The optical waveguide geometries in the volume of the resist material are three-dimensionally structured using a direct-writing lithography device operating on the basis of the machine-readable dataset. The structured resist material is treated using physical or chemical methods to form at least one optical waveguide structure having ends connected to predetermined connecting locations of the optical waveguides.
US09034220B2 Restoration and preservation formulation for polymeric products
A composition for restoration and treatment of polymeric materials and related methods of manufacture are provided; and the composition comprises: at least one solvent and at least one UV protectant, wherein the solvent is designed to soften a surface of the polymeric material and the UV protectant is designed to bond to the polymeric material to restore color and appearance of the polymeric material.
US09034217B2 Voltage nonlinear resistor
The present invention provides a voltage nonlinear resistor containing zinc oxide as a major component, wherein the degree of orientation f(100) of the (100) plane of zinc oxide is 0.40 or more and is represented by the following equation: f(100)=I(100)/(I(100)+I(002)+I(101)), where I(hkl) represents the peak intensity (integral) of a (hkl) plane.
US09034214B2 Fine silver particle powder, method for manufacturing the same, silver paste using the powder, and method of use of the paste
A method suitable for mass production of nanoparticles with a uniform particle diameter is provided. It is an object to provide a powder of the nanoparticle obtained by this method, a dispersion containing the nanoparticles, and a paste containing the nanoparticles. There is provided a method for manufacturing silver particles including the step of reducing silver in a silver solution containing a protective agent composed of an organic material and a copper component in an amount of 1 to 1,000 ppm relative to the amount of silver to obtain particles having an average particle diameter (DTEM) of 5 to 100 nm as measured using a transmission electron microscope.
US09034213B2 Separation of single-walled carbon nanotubes by electronic type using block copolymers
The separation of single-walled carbon nanotubes (SWNTs), by electronic type using centrifugation of compositions of SWNTs and surface active block copolymers in density gradient media.
US09034211B2 Composite conductive polymer composition, method of manufacturing the same, solution containing the composition, use of the composition
The purpose is to provide a technique which enables various kinds of conductive polymer composition to be dissolved in an organic solvent and to be used to form a conductive membrane on a target portion easily. Provided is a composite conductive polymer composition, a method of manufacturing the same, and a solution obtained by dissolving the composition in a alcohol-based, glycol-based, or ether-based solvent. The composition is obtained by doping a π-conjugated polymer (β) with a polymer compound (A), wherein the polymer compound (A) is obtained from (a-1) a monomer having a sulfonic acid group and a polymerizable vinyl group in an amount of 20 to 75 mol %, (a-2) a polar monomer having a hydrophilic group and a polymerizable vinyl group in an amount of 20 to 80 mol %, and (a-3) another polymerizable monomer in an amount of 0 to 20 mol %, and the π-conjugated polymer (β) is obtained from a monomer compound selected from the formulas (I) to (III) in the formula (I) to (III), at least one of R1 to R4 represent —OH or an alkoxy group of C1 to C6, and the other groups represent H, —OH, alkyl group of C1 to C4, or an alkoxy group of C1 to C6; at least one of R5 and R6 represent —OH or an alkoxy group of C1 to C6, and the other group represents H, —OH, an alkyl group of C1 to C4, or an alkoxy group of C1 to C6, or R5 and R6 jointly represent an alkylenedioxy group of C1 to C8; and R7 represents H, —OH, an alkyl group of C1 to C6 or an aromatic ring group.
US09034210B2 Feedstock and method for preparing the feedstock
A feedstock for injection molding includes a ceramic filler that is sinterable to produce a ceramic with a positive temperature coefficient of electrical resistance, a matrix for binding the ceramic filler, the matrix having a melting point lower than a melting point of the ceramic filler, and metallic impurities. A content of the metallic impurities in the feedstock is lower than 10 ppm.
US09034207B2 Phosphor, manufacturing method of phosphor and light emitting device including the same
A phosphor is represented by a general Formula: EuxMyL3−x−ySi6−zAlzN11−(z+y+z)O(z+y+z) and satisfies 0.00001≦x≦2.9999, 0.0001≦y≦2.99999 and 0≦z≦6.0. L is at least one element selected from La, Y, Gd and Lu. M is at least one element selected from Ca, Sr, Ba and Mn.
US09034205B2 Luminescent material and preparation method thereof
The formula of a luminescent material is NaY1-xLnxGeO4, wherein Ln is lanthanon, and the value of x is 0
US09034204B2 Gold coating of rare earth nano-phosphors and uses thereof
Novel core-shell nanoparticles comprising a phosphorescent core and metal shell as well as methods of synthesizing and using said core-shell nanoparticles are provided. In a preferred embodiment, the phosphorescent core comprises an upconverting phosphor and the shell comprises gold.
US09034200B2 Plasma etching of diamond surfaces
The present invention relates to a method of producing a diamond surface including the steps of providing an original diamond surface, subjecting the original diamond surface to plasma etching to remove at least 2 nm of material from the original surface and produce a plasma etched surface, the roughness Rq of the plasma etched surface at the location of the etched surface where the greatest depth of material has been removed satisfying at least one of the following conditions: Rq of the plasma etched surface is less than 1.5 times the roughness of Rq of the original surface, or Rq of the plasma etched surface is less than 1 nm.
US09034197B2 Method for separately processing regions on a patterned medium
The disclosure relates generally to a method for fabricating a patterned medium. The method includes providing a substrate with an exterior layer under a lithographically patterned surface layer, the lithographically patterned surface layer comprising a first pattern in a first region and a second pattern in a second region, applying a first masking material over the first region, transferring the second pattern into the exterior layer in the second region, forming self-assembled block copolymer structures over the lithographically patterned surface layer, the self-assembled block copolymer structures aligning with the first pattern in the first region, applying a second masking material over the second region, transferring the polymer block pattern into the exterior layer in the first region, and etching the substrate according to the second pattern transferred to the exterior layer in the second region and the polymer block pattern transferred to the exterior layer in the first region.
US09034196B2 Microfluidic device with a filter
A microfluidic device with a filter includes a substrate; a flowpath including a well formed in the substrate in fluid communication with a channel formed in the substrate; and a filter disposed across the flowpath and associated with the channel.
US09034195B2 Diffuser/emulsifier for aquaculture applications
A method of treatment of water in an aquatic environment. Water is first pumped from a reservoir to a first mixing station. An inert gas is introduced into the pumped water at the first mixing station to provide inert gas saturated water, which inert gas saturated water will displace undesired gasses in the water in the reservoir. The inert gas saturated water is then pumped to a sparging column such that the inert gas and undesired gasses will be released from the inert gas saturated water to provide depleted water.
US09034191B2 Vibration-assisted dialysis method
Disclosed herein are an apparatus and method of increasing dialysis dose and waste removal with the introduction of mechanical energy, such as vibration, to a hemodiafiltration membrane The method generally includes providing a dialyzer that includes a vibration element in engaged vibratory communication with a hemodiafiltration membrane The method also includes enabling extracorporeal flow of pre-dialyzed blood and a dialysate through the dialyzer and respectively past opposing surfaces of a vibrating hemodiafiltration membrane to achieve a solute clearance from the pre-dialyzed blood that is at least about 10% greater than a solute clearance from the pre-dialyzed blood obtained in the absence of the engaged vibratory communication Various apparatus are also disclosed, each of which includes a vibration element in vibratory communication with the dialyzer.
US09034189B2 Pressurized hollow fiber membrane module
Disclosed is a pressurized hollow fiber membrane module that exhibits improved durability without deterioration in packing density and permeation flux. The pressurized hollow fiber membrane module includes a composite hollow fiber membrane comprising a tubular braid woven by yarns and a polymer film on the outer surface of the tubular braid. At least one of the yarns comprises a small-fineness filament and a medium-fineness filament. The small-fineness filament comprises first monofilaments having a fineness of 0.01 to 0.4 denier, the medium-fineness filament comprises second monofilaments having a fineness higher than 0.4 and lower than 3, and a ratio of thickness of the tubular braid to outer diameter thereof is 15 to 35%.
US09034188B2 Cleaning structure for floating oil and substance on water surface
A cleaning structure for floating oil and substance on water surface provided by the present invention comprises at least one cleaning ball and a threading rope. The cleaning ball comprises a plurality of yarns arranged in parallel, and a tie is used for bundling the yarns at the middle section to form a ball structure. A fixing ring is threaded with the tie, and the threading rope is threaded through the fixing ring of each of the cleaning balls. The tie of each of the cleaning balls can be threaded with the threading rope in equal intervals beforehand, and the cleaning balls formed by bundling the side by side arranged yarns with the ties are arranged on the threading rope in equal intervals to form the cleaning structure. The yarns of the cleaning ball can be made of water repellent fiber yarn or water repellent reticulated yarn which can be spread as an expanded absorbing surface while floating on water surface, and the gaps of each of the fiber yarns are formed as spaces for absorbing floating oil and substance. The cleaning structure made of the water repellent material can be prevented from absorbing water and sinking. Thereby, floating oil and substance can be cleaned effectively.
US09034183B2 Method for sanitizing water dispensed from a water dispenser having a reservoir
A method and apparatus of sanitizing drinking water to be dispensed from a water dispenser having a reservoir includes the steps of providing the ozone gas generator that generates an ozone gas stream, transmitting the ozone gas stream from the generator to the water dispenser reservoir, mechanically breaking up the ozone gas stream inside the reservoir to produce ozone gas bubbles, and using the ozone gas bubbles to disinfect water in the reservoir. The ozone gas stream can be mechanically broken up using a pump such as, for example, an impeller type pump.
US09034178B2 Fluid filter assembly with sight glass
A fluid filter assembly with sight glass provides an upper housing carrying a transparent sight glass for visualizing the interior of the filter assembly and fluids passing therethrough. A sight glass retainer secures the sight glass within the upper housing. A screen filter is carried between the upper housing and a mating lower housing. A fluid inlet port is defined in the upper housing above the screen filter and a fluid output port is defined in the lower housing below the screen filter. The sight glass retainer carries plural fluid deflectors and plural sight glass supports for fluid dispersion and fluid cooling. A pressurized air input communicating with fluid inlet port allows pressurized air to be injected into the assembly to force fluids through the screen filter and out of the filter assembly. A low pressure drain valve and a bypass valve are carried in the lower housing.
US09034177B2 Drainage device for closed chamber containing liquid
A drainage device for draining liquid out of a closed chamber includes an air cylinder, a driving assembly, a first channel, a second channel, a first sealing assembly, a second sealing assembly, and a controller. The air cylinder includes a main body defining a receiving chamber, an action piston positioned in the receiving chamber of the main body, and a connecting rod connected to the action piston. The main body defines a liquid inlet and a liquid outlet, both of which communicate with the receiving chamber, and the presence of a fixed piston with a seal in each of the inlet and outlet creates a double-acting one-way valve when the action piston is moved up and down.
US09034176B2 Radio frequency heating of petroleum ore by particle susceptors
A method for heating materials by application of radio frequency (“RF”) energy is disclosed. For example, the disclosure concerns a method for RF heating of petroleum ore, such as bitumen, oil sands, oil shale, tar sands, or heavy oil. Petroleum ore is mixed with a substance comprising susceptor particles that absorb RF energy. A source is provided which applies RF energy to the mixture of a power and frequency sufficient to heat the susceptor particles. The RF energy is applied for a sufficient time to allow the susceptor particles to heat the mixture to an average temperature greater than about 212° F. (100° C.). Optionally, the susceptor particles can be removed from the mixture after the desired average temperature has been achieved. The susceptor particles may provide for anhydrous processing, and temperatures sufficient for cracking, distillation, or pyrolysis.
US09034172B2 Electrochemical test sensor
An electrochemical test sensor for detecting the concentration of an analyte in a fluid sample. The electrochemical test sensor includes a housing that has a first end and a second opposing end. The housing includes an opening at the first end to receive a fluid test sample. An electrode assembly includes a substrate, a working electrode, a counter electrode and a reagent. The substrate has a first surface and an opposing second surface. The working electrode is disposed on the first surface of the substrate, and the counter electrode is disposed on the second surface of the substrate. The electrode assembly is positioned within the housing to define a reaction channel. The electrochemical test sensor may be used with a removable lancet mechanism or integrated within a lancet mechanism to form one integral unit.
US09034161B2 Sperm separation devices and associated methods
The present invention provides methods, devices, and kits for separating and selecting top sperm from a sperm sample of a subject. In one aspect, for example, such a method can include removing a portion of negatively charged protein from sperm in the sperm sample, immobilizing the sperm, electrophoretically separating the sperm, and selecting mature sperm based on electromotility properties.
US09034156B2 Sputtering apparatus
Provided is a sputtering apparatus which deposits a metal catalyst on an amorphous silicon layer at an extremely low concentration in order to crystallize amorphous silicon, and particularly minimizes non-uniformity of the metal catalyst caused by a pre-sputtering process without reducing process efficiency. This sputtering apparatus improves the uniformity of the metal catalyst deposited on the amorphous silicon layer at an extremely low concentration. The sputtering apparatus includes a process chamber having first and second regions, a metal target located inside the process chamber, a target transfer unit moving the metal target and having a first shield for controlling a traveling direction of a metal catalyst discharged from the metal target, and a substrate holder disposed in the second region to be capable of facing the metal target. A distance difference between a linear distance, which is a distance between a substrate loaded on the substrate holder and the metal target, and a length of the first shield is less than 3 cm.
US09034155B2 Inorganic-particle-dispersed sputtering target
Provided is an inorganic-particle-dispersed sputtering target in which inorganic particles are dispersed in a Co base material, wherein the inorganic particles have an electric resistivity of 1×101 Ω·m or less and the volume ratio of the inorganic particles in the target is 50% or less. The sputtering target thus adjusted is advantageous in that, when sputtering is performed using a magnetron sputtering device comprising a DC power source, the inorganic particles are less charged, and arcing occurs less frequently. Accordingly, by using the sputtering target of the present invention, the occurrence of particles attributable to the arcing reduces, and a significant effect of improving the yield in forming a thin film is obtained.
US09034153B2 Nonmagnetic material particle dispersed ferromagnetic material sputtering target
Provided is a nonmagnetic material particle dispersed ferromagnetic material sputtering target comprising a material including nonmagnetic material particles dispersed in a ferromagnetic material. The nonmagnetic material particle dispersed ferromagnetic material sputtering target is characterized in that all particles of the nonmagnetic material with a structure observed on the material in its polished face have a shape and size that are smaller than all imaginary circles having a radius of 2 μm formed around an arbitrary point within the nonmagnetic material particles, or that have at least two contact points or intersection points between the imaginary circles and the interface of the ferromagnetic material and the nonmagnetic material. The nonmagnetic material particle dispersed ferromagnetic material sputtering target is advantageous in that, in the formation of a film by sputtering, the influence of heating or the like on a substrate can be reduced, high-speed deposition by DC sputtering is possible, the film thickness can be regulated to be thin, the generation of particles (dust) or nodules can be reduced during sputtering, the variation in quality can be reduced to improve the mass productivity, fine crystal grains and high density can be realized, and the nonmagnetic material particle dispersed ferromagnetic material sputtering target is particularly best suited for use as a magnetic recording layer.
US09034152B2 Reactive sputtering apparatus
A reactive sputtering apparatus includes a chamber, a substrate holder provided in the chamber, a target holder which is provided in the chamber and configured to hold a target, a deposition shield plate which is provided in the chamber so as to form a sputtering space between the target holder and the substrate holder, and prevents a sputter particle from adhering to an inner wall of the chamber, a reactive gas introduction pipe configured to introduce a reactive gas into the sputtering space, an inert gas introduction port which introduces an inert gas into a space that falls outside the sputtering space and within the chamber, and a shielding member which prevents a sputter particle from the target mounted on the target holder from adhering to an introduction port of the reactive gas introduction pipe upon sputtering.
US09034151B2 Alignment film forming apparatus and method
An alignment film forming apparatus and a method are provided to form an alignment film for a liquid crystal in a single process of simultaneously executing a film deposition process of ion beam sputtering and an alignment process. The method greatly restricts the size of a substrate. An alignment film forming apparatus includes a target disposed on a top surface side of a substrate and having a sputtering surface defining a sharp angle to the top surface of the substrate, a transfer table that transfers the substrate in a predetermined direction, and an ion source disposed on the top surface side of the substrate in such a way that an ion beam is irradiated on the sputtering surface of the target. An ion beam reflected at the sputtering surface is irradiated on a sputtering film formed on the substrate. The apparatus includes a mask disposed in such a way as to cover a part of the top surface of the substrate on an upstream side of a position where the sputtering film is formed, and a temperature regulator which regulates the temperature of the target.
US09034149B2 Method for fabricating a high coercivity hard bias structure for magnetoresistive sensor
A hard bias (HB) structure for longitudinally biasing a free layer in a MR sensor is disclosed that includes a mildly etched seed layer and a hard bias (HB) layer on the etched seed layer. The HB layer may contain one or more HB sub-layers stacked on a lower sub-layer which contacts the etched seed layer. Each HB sub-layer is mildly etched before depositing another HB sub-layer thereon. The etch may be performed in an IBD chamber and creates a higher concentration of nucleation sites on the etched surface thereby promoting a smaller HB average grain size than would be realized with no etch treatments. A smaller HB average grain size is responsible for increasing Hcr in a CoPt HB layer to as high as 2500 to 3000 Oe. Higher Hcr is achieved without changing the seed layer or HB material and without changing the thickness of the aforementioned layers.
US09034147B2 Method to reduce heat radiation losses through coke oven chamber doors and walls by adapting the coal cake in height or density
A method for reducing the coking time in the oven area near the door or end wall and for improving coke quality and situation of emissions by compensating for radiation losses through coke oven chamber doors and end walls is described. This compensation is accomplished by varying the height of the coal cake in the environment of the frontal coke oven chamber doors. The variation is achieved both by increasing or decreasing the coal cake over part of the length or over the entire length of the coke oven chamber door. The reduction in the height of the coal cake can be generated by omission of coal or coal compacts, the increase in height can be accomplished by stacking of coal and pressing or adding of coal compacts, with it also being envisaged to omit the pressing cycle so as to obtain a recess with a lower coal cake density which also has less heat radiation.
US09034145B2 Use of nanocrystaline cellulose and polymer grafted nanocrystaline cellulose for increasing retention, wet strength, and dry strength in papermaking process
The invention provides methods and compositions for improving the characteristics of paper substrates. The method involves adding to a paper substrate an NCC-polymer. NCC-polymers have unique chemical properties which result in improvements in wet strength, dry strength and drainage retention properties of the paper substrates.
US09034143B2 Inductive/capacitive hybrid plasma source and system with such chamber
A plasma processing chamber having capacitive and inductive coupling of RF power. An RF power source is connected to an inductive coil and to a top electrode via a variable capacitor to control the ratio of power applied to the coil and electrode. The bottom electrode, which is part of the chuck holding the substrates, is floating, but has parasitive capacitance coupling to ground. No RF bias is applied to the chuck and/or the substrate, but the substrate is chucked using DC power. In a system utilizing the chamber, the chuck is movable and is loaded with substrates outside the chamber, enter the chamber from one side for processing, exit the chamber from an opposite side after the processing, and is unloaded in an unloading chamber. The chuck is then transported back to the loading chamber. Substrates are delivered to and removed from the system using conveyor belts.
US09034138B2 Method for manufacturing polarizing plate
A method for manufacturing a polarizing plate, the method comprising bonding a first transparent protective film and a second transparent protective film to both sides of a polarizer with an adhesive layer interposed between the polarizer and each of the first and second transparent protective films, wherein the first and second transparent protective films have different elasticities (elastic modulus×thickness (μm)), the three films are pressure-bonded by being simultaneously allowed to pass between a pair of rolls, a direction in which the polarizer is fed and allowed to pass between the pair of rolls is inclined toward the high-elasticity film. The polarizing plate obtained by the method can be suppressed the occurrence of bubbles between the polarizer and the transparent protective films.
US09034137B2 In-situ, multi-stage debulk, compaction, and single stage curing of thick composite repair laminates
A method for fabricating a repair laminate for a composite part having an exposed surface includes applying a bonding material to the exposed surface and forming an uncured ply stack assembly on the bonding material. The uncured ply stack assembly is formed by forming and compacting a series of uncured ply stacks. The ply stack assembly and bonding material are then cured.
US09034136B2 Production method for artificial marble containing amethyst and vermiculite
Provided is a method of producing an artificial marble containing amethyst and vermiculite. The artificial marble includes amethyst representing superior performance in terms of a far-infrared emission effect and an antimicrobial property with a fine appearance, and vermiculite serving as an inorganic filler material and representing a superior adiabatic effect with a light weight. The artificial marble has a structure in which the first base layer including amethyst and the second base layer including vermiculite are laminated on each other.
US09034131B2 Method and apparatus for arranging granular material
A method includes steps of: carrying an air-permeable web while holding the first surface of the web on a carrying surface; dispensing powder particles onto the second surface of the web; drawing the first air from a plurality of suction holes in the carrying surface through the web, thereby holding the powder particles in a predetermined pattern on the second surface of the web; and giving at least a part of the first air flow components flowing in directions along the second surface of the web by means of an airflow deflector opposing the second surface of the web, thereby moving powder particles on non-suction areas between the suction holes on the web, thus arranging the powder particles in a predetermined pattern on the web.
US09034123B2 Cu—Ni—Si-based copper alloy sheet material and method of manufacturing same
This invention provides a copper alloy sheet material containing, in mass %, Ni: 0.7%-4.2% and Si: 0.2%-1.0%, optionally containing one or more of Sn: 1.2% or less, Zn: 2.0% or less, Mg: 1.0% or less, Co: 2.0% or less, and Fe: 1.0% or less, and a total of 3% or less of one or more of Cr, B, P, Zr, Ti, Mn and V, the balance being substantially Cu, and having a crystal orientation satisfying Expression (1): I{420}/I0{420}>1.0  (1), where I{420} is the x-ray diffraction intensity from the {420} crystal plane in the sheet plane of the copper alloy sheet material and I0{420} is the x-ray diffraction intensity from the {420} crystal plane of standard pure copper powder. The copper alloy sheet material has highly improved strength, post-notching bending workability, and stress relaxation resistance property.
US09034109B2 Dishwasher with wash load detection
A method of operating a dishwasher having a tub at least partially defining a treating chamber for receiving utensils and a spraying system spraying liquid in the treating chamber, to determine at least one parameter of the cycle of operation based on the set of load condition by selectively spraying liquid in multiple portions of the treating chamber.
US09034105B2 Solid precursor sublimator
An apparatus and method for holding a solid precursor in a sublimator such that the solid precursor can be vaporized for saturating a carrier gas. The apparatus may include alternating disks or shelves that form inner and outer passages, as well as spaces between the disks for fluidicly coupling the passages to create a winding, tortuous fluid flow path through the sublimator for optimizing solid vapor saturation. The method may include directing a carrier gas into a sublimation chamber, around the first shelf in the outer passage, over the first shelf in the space, around the second shelf in the inner passage, and back out of the sublimation chamber.
US09034099B2 Cement that is resistant to internal sulfate reactions and to external sulfate attacks
The present invention relates to a novel cement which makes possible the preparation of concrete, grout or mortar which is resistant to internal sulfate reactions and to external sulfate attacks, and also the use of this cement for the preparation of concrete, grout or mortar.
US09034095B2 Greenish blue pigment, colorant composition containing said pigment, and image recording material
An object is to overcome the drawbacks of conventional blue phthalocyanine pigments upon the formation of images, and to develop a blue pigment that can satisfactorily exhibit a greenish blue color high in chroma and excellent in colorfulness, brightness, dispersibility, hue, tinting power and the like and that is applicable to various image recording methods. The object can be achieved by a greenish blue pigment, which exhibits a greenish blue hue of high chroma and contains a pigment represented by the following formula (I): wherein the number, m, of substituent phthalimidomethyl group(s) is in a range of 1.0≦m≦5.0, and the number, n, of a substituent sulfonic group R1 is in a range of 0.05≦n≦1.0.
US09034093B2 Process for improving the transfer properties of bitumen
Additives may be used to lower the set up point for bitumen thereby allowing it to be transported from place to place more easily. Additives useful for lowering the set up point of bitumen include alkylphenol formaldehyde resins and oxyalkylated alkylphenol formaldehyde resins; amines and esters; solvents; and combinations thereof.
US09034089B2 Ink formulation
The disclosed invention relates to the use of molybdenum (VI) peroxo complex containing an amino acid, such as MoO(O2)2(GLY)(H2O), in marking applications, as well as to ink formulations comprising such complexes.
US09034085B2 Aliphatic amine based nanocarbons for the absorption of carbon dioxide
A composition of matter, and method to make same, for a nano-based material including a nanocarbon support to which is attached an aliphatic amine. In particular, the composition of matter is an aliphatic amine-nanocarbon material that includes a nanocarbon (NC) support, such as C60, nano-graphite, graphene, nanocarbon ribbons, graphite intercalation compounds, graphite oxide, nano-coal, nanohorns, and combinations thereof, and further includes an aliphatic amine, such as polyethyleneimine (PEI).
US09034083B2 Array of hollow fibers and a system and method of manufacturing same
An array of hollow fibers including a plurality of hollow fibers of a predetermined diameter configured to receive a gas having oxygen therein and transfer the oxygen to a fluid and/or transfer carbon dioxide in the fluid to a gas. The array is configured in a predetermined pattern having a predetermined packing density that is a fraction of a total cross-sectional area of the array occupied by the hollow fibers.
US09034081B2 Down-flow direct contact cooler
Systems and methods are contemplated for down-flow cooling of a feed gas. Contemplated systems can include a housing having an inlet conduit disposed within an upper portion and configured to receive a first stream. First and second stages can be disposed within the housing, with the first stage disposed upstream of the second stage and having a first cooling stream, and the second stage having a second cooling stream that is colder than the first cooling stream. The housing can be configured such that the first stream is cooled by down-flow heat exchange with the first and second cooling streams to produce a conditioned stream depleted of at least a portion of water condensed from the feed gas.
US09034080B2 Method and device for producing a fluid enriched with carbon dioxide from a waste gas of a ferrous-metallurgy unit
The present invention relates to a process and apparatus for producing a fluid enriched in carbon dioxide starting from a waste gas from a ferrous metallurgy unit.
US09034077B2 Fast gas chromatograph method and device for analyzing a sample
A fast gas chromatograph (GC) method and device for obtaining fast gas chromatography analysis, in which a capillary gas chromatography column is inserted into a resistively heated metal tube located mostly outside a heated oven, which serves as a heated transferline to a flexible column that enters a resistively heated metal tube from a gas chromatograph injector and exits into a gas chromatograph detector. The resistively heated metal tube of the fast GC device has an internal diameter that is over twice the external diameter of the GC column so as to enable the insertion of several capillary GC column loops. The process of column insertion into or removal from the heated tube is aided by touching it with an ultrasound vibrating device that remarkably reduces the friction during column insertion into the metal tube heater.
US09034074B2 Process for producing reduced iron pellets, and process for producing pig iron
In a method for producing a reduced iron pellet, when a powder formed article including iron oxide and carbon is heated and reduced in a rotary hearth furnace, a formed article produced using a raw material, in which an average diameter of the iron oxide is 50 microns or less and a ratio of carbon monoxide to carbon dioxide in a reduction zone is from 0.3 to 1, is reduced at a temperature of 1400° C. or less, thereby producing a reduced iron pellet in which a metallization ratio of iron is 50 to 85% and a ratio of residual carbon is 2% or less.
US09034073B2 Method for making metal-based nano-composite material
A method for making a metal-based nano-composite material is disclosed. In the method, a semi-solid state metal-based material is provided. The semi-solid state metal-based material is stirred and nano-sized reinforcements are added into the semi-solid state metal-based material to obtain a semi-solid state mixture. The semi-solid state mixture is heated to a temperature above a liquidus temperature of the metal-based material, to achieve a liquid-metal-nano-sized reinforcement mixture. The liquid-metal-nano-sized reinforcement mixture is ultrasonically processed at a temperature above the liquidus temperature by conducting ultrasonic vibrations to the liquid-metal-nano-sized reinforcement mixture along different directions at the same time.
US09034072B2 Compositions of substantially spherical particles and methods of making thereof
An improved composition comprising substantial spherical UFP particles and an active agent, such as NBPT, and optionally other components is used as an additive for liquid and solid fertilizers, typically containing urea. Methods of making the compositions and their use are also disclosed.
US09034069B2 Engineered topsoil for use in land reclamation and a method of producing the same
An engineered topsoil for use in soil reclamation and a method of producing the same are disclosed that seek to replicate undisturbed native reference topsoil from near the site in need of land reclamation. The engineered topsoil is formed from a base amount of subsoil and amendment comprised of an effective amount of surrogate humin material sufficient to replicate the estimated humin organic carbon content of the native reference topsoil, and an effective amount of plant residue material sufficient to replicate the estimated non-humin organic carbon content of the native reference topsoil.
US09034067B2 Cyclone separating apparatus of vacuum cleaner
A multi-cyclone separating apparatus of vacuum cleaner comprises a upstream cyclone forming upstream separating chamber inside, downstream cyclones at least one of which forming downstream separating chamber inside, the upper part of the upstream cyclone chamber is connected with an air inlet passage, said upstream cyclone has a upstream guide air intake inside, the downstream cyclone has a downstream air intake and the downstream cyclone has a downstream guide outlet inside, an air passage is formed between upstream guide air intake and downstream guide outlet which connected with the two. The multi-cyclone separating apparatus also comprises an outer cyclone body, the upstream cyclone is located inside of the outer cyclone body and the entrance of air inlet passage is located at the outer cyclone body or extend to the outside of the outer cyclone body.
US09034065B2 Exhaust gas purification system
A diesel particulate defuser (DPD) for collecting particulate matter (PM) in exhaust gas is connected to an exhaust pipe of a diesel engine, and when the amount of PM in the DPD becomes equal to or greater than a predetermined amount, the exhaust gas temperature of the diesel engine is increased by performing exhaust pipe injection and DPD is automatically regenerated. In such an exhaust gas purification system, an exhaust gas temperature during DPD regeneration in automatic regeneration is detected, a difference between the detected exhaust gas temperature and a target regeneration temperature is determined, and in a case where an exhaust pipe injection amount is PID controlled based on the difference, when a transition is made from the traveling automatic regeneration to the idle automatic regeneration conducted during a stop, an integral control term in the PID control is reset to zero to control the exhaust pipe injection amount.
US09034061B2 Agglomerated particulate low-rank coal feedstock and uses thereof
The present invention relates generally to processes for preparing agglomerated particulate low-rank coal feedstocks of a particle size suitable for reaction in a fluidized-bed reactor and certain other gasification reactors and, in particular, for coal gasification and combustion applications. The present invention also relates to integrated coal gasification and combustion processes including preparing and utilizing such agglomerated particulate low-rank coal feedstocks.
US09034058B2 Agglomerated particulate low-rank coal feedstock and uses thereof
The present invention relates generally to processes for preparing agglomerated particulate low-rank coal feedstocks of a particle size suitable for reaction in certain gasification reactors and, in particular, for coal gasification. The present invention also relates to integrated coal gasification processes including preparing and utilizing such agglomerated particulate low-rank coal feedstocks.
US09034056B2 Foam dyeing agent for keratinous fibers with improved color uptake
The present application provides preparations for changing the color of keratinic fibers, containing in a cosmetically acceptable carrier, at least one color-changing agent, at least one soap, at least one non-ionic surfactant of formula (I), in which R1 denotes an alkyl or alkenyl residue having 5 to 21 carbon atoms, R2 denotes a C2-C4 monohydroxyalkyl residue, and R3 denotes hydrogen, a C1-C4 alkyl residue or a C2-C4 monohydroxyalkyl residue, and at least one propellant wherein the preparation is in the form of a foam, and a proportion of gas in the foam is at least 50% by volume.
US09034053B2 Methods and devices for conduit occlusion
The present invention comprises systems, methods and devices for the delivery of compositions for occluding or of means for opening conduits. The implantable occlusive material may be delivered pre-formed or in situ cured and, may be a resorbable material that supports tissue ingrowth that eventually replaces the material leaving little or no original material in place. The delivery system is positioned to allow for placement of the occlusive material into the body conduit. Use of delivery systems, methods and devices for re-opening an occluded body conduit are also included.
US09034052B2 Delivery systems containing bioactive materials
A delivery system comprising a covering containing at least a first substance for release to a surgical site is provided. The covering includes an elongated containment portion having at least one compartment, wherein the covering includes an elongated containment having a first end and a second end. At one end the elongated containment defines an opening configured to receive at least one substance. The at least one substance can be DBM or a mixture of demineralized fibers and particles in a ratio of 30:70. The delivery system also includes a closing member that can close the elongated containment prior to insertion at a surgical site. The closing member can be drawing strings, stitches, sutures, wing sutures, heat seals, adhesion, pressure fittings, coil ring, twist tie. The substance contained in the delivery system can also be enclosed by twisting and folding over a portion of the covering.
US09034051B2 Bone repair material and method for producing the same
A bone repair material being superior in apatite-forming ability and its stability in a storage and high in scratch resistance is disclosed. The material is produced by a method comprising the steps of: immersing a substrate made of titanium or a titanium alloy in a first aqueous solution that does not contain calcium ions but contains at least one cation selected from the group consisting of sodium ions and potassium ions and is alkaline; immersing the substrate in a second aqueous solution that does not contain phosphate ions but contains calcium ions; heating the substrate in a dry atmosphere; and treating the substrate with hot water of 60° C. or higher or with steam.
US09034036B2 Seamless-vision, tilted intraocular lens
A variable focus intraocular lens comprises an optic coupled to at least one haptic at a rigid flexion that sets a non-zero angle between the optic and the haptic.
US09034034B2 Devices for reducing left atrial pressure, and methods of making and using same
A device for regulating blood pressure between a patient's left atrium and right atrium comprises an hourglass-shaped stent comprising a neck region and first and second flared end regions, the neck region disposed between the first and second end regions and configured to engage the fossa ovalis of the patient's atrial septum; and a one-way tissue valve coupled to the first flared end region and configured to shunt blood from the left atrium to the right atrium when blood pressure in the left atrium exceeds blood pressure in the right atrium. The inventive devices may reduce left atrial pressure and left ventricular end diastolic pressure, and may increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits. The inventive devices may be used, for example, to treat subjects having heart failure, pulmonary congestion, or myocardial infarction, among other pathologies.
US09034032B2 Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods
Devices and methods for implantation at a native mitral valve having a non-circular annulus and leaflets. One embodiment of the device includes a valve support having a first region configured to be attached to a prosthetic valve with a plurality of prosthetic leaflets and a second region. The device can further include an anchoring member having a longitudinal dimension and including a first portion configured to contact tissue at the non-circular annulus, a second portion configured to be attached to the valve support, and a lateral portion between the first portion and the second portion. The second portion of the anchoring member is attached to the second region of the valve support while in a low-profile configuration in which the anchoring member and the valve support are configured to pass through vasculature of a human. The lateral portion is transverse to the longitudinal dimension. The anchoring member and the valve support are configured to move from the low-profile configuration to an expanded configuration in which the first portion of the anchoring member at least partially adapts to the non-circular annulus of the native mitral valve and the first region of the valve support is spaced inwardly from the first portion of the anchoring member relative to the longitudinal dimension of the anchoring member such that a shape of the first region of the valve support is at least partially independent of a shape of the first portion of the anchoring member.
US09034031B2 Prosthetic device including electrostatically spun fibrous layer and method for making the same
In accordance with certain embodiments of the present disclosure, a process of forming a prosthetic device is provided. The process includes forming a dispersion of polymeric nanofibers, a fiberizing polymer, and a solvent, the dispersion having a viscosity of at least about 50,000 cPs. A tubular frame is positioned over a tubular polymeric structure. Nanofibers from the dispersion are electrospun onto the tubular frame to form a prosthetic device. The prosthetic device is heated.
US09034030B2 Helical arm tie down
An arrangement for temporarily retaining a side arm (36) of a stent graft (30) in a selected position during loading thereof onto a deployment device, the side arm extending from an ostium (38) in the tubular body (32) and substantially helically around and along the tubular body to an open end (40). A first tie down wire (48) is stitched through the tubular body and through the side arm and then through the biocompatible graft material of the tubular body at the open end of the side arm. The stent graft can then be loaded into a sheath of a deployment device for the stent graft. There can be a second tie down wire (50) stitched through the biocompatible graft material of the tubular body and through the side arm and then through the biocompatible graft material of the tubular body at the ostium end of the side arm. The first and/or second tie down wires can be withdrawn after the stent graft is loaded into the sheath or left in place until delivery.
US09034026B2 Implant for influencing blood flow
An implant for blood vessels, in particular to influence the flow of blood in the area of arteriovenous malformations. The implant has a wall comprising individual filaments combined so as to form a circular braiding, the circular braiding being positioned in elongated form and with a reduced diameter in an insertion catheter and expanding at the placement site thus adapting to the vessel diameter and increasing its braiding density.
US09034024B2 Method for treatment of varicocele
A minimally invasive method for treating varices in especially sensitive areas, including pelvic varices in females, varicoceles, and also oesophageal varices is presented. The method comprises the steps of making a micro incision into the blood vessels of a patient, endoscopically inserting a catheter device into the blood vessel of a patient and advancing the distal end of the catheter to reach the varix or varices. For treatment of male varicocele, insertion is preferably made directly at the testicle. Alternatively, insertion can be made in the femoral vein and advanced using a catheter. Preferably, x-ray, angiography, or other imaging techniques are used to visualize and position the catheter. An optical fiber is then inserted into the catheter and the distal end is advanced to a predetermined point near the varix or varices. Optical fiber distal end is preferably a slim, radial 360 degree emitting fiber end. Laser energy of preferably 1470±30 nm is then transmitted to the varix to close the blood vessel. Other wavelengths with similar or greater absorption in blood/water than at 1470 nm are also effective. Imaging techniques such as angiographies may again be performed to confirm closure of the vein. The laser source linked to a radial emitting fiber allows for thermo occlusion of varicoceles using about 2-3 W of emitting power with little or no pain or discomfort for patient. The present invention is an out-patient procedure that requires no anesthesia and minimal recovery time, and does not require that any foreign objects be left in the body. This method has been shown to have a high success rate and minimum pain or side effects for the patient.
US09034018B2 Spinal stabilization system with rigid and flexible elements
A spinal stabilization system generally comprises first and second anchor members configured to be secured to first and second vertebrae within a patient's body, a flexible element secured to the first anchor member, and a rigid element secured to the second anchor member. An end portion of the rigid element is coupled to an end portion of the flexible so that the system is able to provide both rigid and dynamic stabilization. The coupling is maintained even if the flexible element relaxes after a period of time within the patient's body.
US09034015B2 Surgical device for correction of spinal deformities
The present invention relates generally to a surgical device for the correction of deformities of the spinal column and finds particular, although not exclusive, utility in devices which are surgically implantable. Presently known implantable surgical devices are unable to provide for the progressive correction of spinal deformities assisted by active movements of the human body without fusion of the involved part of the spinal column. The present surgical device comprises a spinal column straightening means for permitting the relative rotation of two substantially adjacent vertebrae about a common axis substantially only in opposite rotational directions.
US09034013B2 Systems, devices, and methods for securing tissue using a suture having one or more protrusions
Systems, devices, and methods are provided for securing soft tissue to bone. One exemplary embodiment of a surgical repair construct includes an anchor, a filament having a snare on one end and a collapsible loop on another end, and a suture having a plurality of stationary protrusions. The suture is configured to be coupled to detached tissue and have its ends passed through an opening in the snare. The snare can be collapsed around the suture so at least one of the protrusions is proximal of the collapsed snare. The anchor can be disposed in bone and the filament coupled thereto. Accordingly, collapsing the snare around the suture couples the tissue to bone, and applying tension to a tensioning limb of the filament can collapse the loop to incrementally tighten and secure the tissue to bone. Other exemplary systems, devices, and methods for use with tissue repair are also provided.
US09034006B2 Method and apparatus for retrieving an embolized implant
A retrieval portion is attached to an implantable device to facilitate retrieval of the implantable device in the unlikely event of embolization. The retrieval portion may comprise one or more loops, or a plurality of extensions. Methods of retrieving an implantable device are disclosed. Various adapters are disclosed for use with a conventional snare for grasping an implantable device.
US09034005B2 Vascular embolization with an expansible implant
A vascular implant formed of a compressible foam material has a compressed configuration from which it is expansible into a configuration substantially conforming to the shape and size of a vascular site to be embolized. Preferably, the implant is formed of a hydrophilic, macroporous foam material, having an initial configuration of a scaled-down model of the vascular site, from which it is compressible into the compressed configuration. The implant is made by scanning the vascular site to create a digitized scan data set; using the scan data set to create a three-dimensional digitized virtual model of the vascular site; using the virtual model to create a scaled-down physical mold of the vascular site; and using the mold to create a vascular implant in the form of a scaled-down model of the vascular site. To embolize a vascular site, the implant is compressed and passed through a microcatheter, the distal end of which has been passed into a vascular site. Upon entering the vascular site, the implant expands in situ substantially to fill the vascular site. A retention element is contained within the microcatheter and has a distal end detachably connected to the implant. A flexible, tubular deployment element is used to pass the implant and the retention element through the microcatheter, and then to separate the implant from the retention element when the implant has been passed out of the microcatheter and into the vascular site.
US09033999B2 Surgical threading device with removable suture
A threading device assembly for use in plastic surgery that includes a threading rod and a removable suture assembly secured to the threading rod. The threading rod includes an elongated tube with first and second opposite ends and a reduced diameter portion defined therein, and a translucent light guide extending through the elongated tube. The light guide allows light to be transmitted through the material comprising the light guide from one end of the tube to the other. The removable suture assembly includes a cuff positioned in and at least partially around the reduced diameter portion of the elongated tube, and a suture secured to the cuff.
US09033996B1 System, method and apparatus for placing therapeutic devices in a heart
The present invention relates to a system and method for positioning a sheath and guiderail catheter into the Coronary Sinus (CS) to introduce pacing therapy within a heart of a subject. The guiderail catheter can be customized into a shape compatible with the subject's anatomy and also provide for shapeability of the guiderail catheter. The method includes introducing the sheath into the heart of the subject, with the sheath positioned in the right atrium. The guiderail catheter is introduced into the heart of the subject through the distal end of the sheath and advanced past the distal end of the sheath into the right atrium of the heart to a position near the septum and further guiding the distal end of the guiderail catheter into the coronary sinus.
US09033994B2 Bone graft delivery device
Aspects of the claimed invention relate generally to devices for delivering bone graft compositions to implants that have been positioned between vertebral bodies during surgery and methods of using such devices. Embodiments of the invention provide ease of bone graft delivery in situ while providing an environment for the mixing of bone graft, insertion of the bone graft, and packing of the graft into the voids above and below the implant.
US09033979B2 Articulating ablation and division device with blood flow sensing capability
A laparoscopic liver resection device is described. The device combines the Radiofrequency Ablation (RFA) technology with a cutting mechanism, a blood-flow sensor and a flexible actuation mechanism to simultaneously coagulate and cut the liver tissue and detect the presence of blood flow to confirm avascularity. The present invention eliminates the risk of excess bleeding due to cutting too deep and reduces recovery time and the time spent on re-coagulation of coagulated areas, thereby shortening duration of surgery. Also embodiments prevent excess ablation by stopping ablation activity on the target tissue as soon as insufficient or no blood flow in the target tissue is detected. Thus a closed loop control for a bloodless tissue/organ division method is provided.
US09033978B2 High-frequency treatment instrument
A high-frequency treatment instrument having a sheath; an elongated extension member; a narrow portion provided on an inner surface of the sheath; and a pressing member which allows the elongated extension member to advance and retract only in a part of the sheath. The elongated extension member is advanced to form a first treatment electrode extending along a central axial line of the sheath and the elongated extension member is further advanced to form a second treatment electrode which intersects with the central axial line of the sheath.
US09033974B2 Multi-functional surgical cautery device, system and method of use
A surgical cautery device, system, and method of use may apply bipolar and/or sesquipolar electrocautery to target tissue via a pair of instruments with other primary surgical functions. The surgical cautery device and system may include first and second elements capable of forming an electrical circuit. The second element may be independently positionable with respect to the first element. The first and second elements may also include a surgical component with an independent surgical function. Exemplary surgical components include a rotary blade, a cutting tool, a grasper tool, a micro-scissors tool, a micro-grasping forceps tool, a dissector, a micro-dissector, curette, and a suction cannula. On some occasions, one of the surgical components may be interchangeable with another surgical component.
US09033968B1 Methods and systems of temperature based alarms, esophageal cooling and/or automatic interrupt (shut-off) during a cardic ablation procedure
A method and system for increasing safety of cardiac ablation procedures comprises a computer based system that monitors the esophageal temperature. During atrial fibrillation ablations, based on a pre-determined increase in esophageal temperature, the computer based system activates different levels of alarm(s), and/or initiates ablation energy interrupt based on pre-defined programmed values. In one embodiment, an esophageal cooling means is incorporated for cooling the esophagus during the procedure. If the temperature starts to increase a cooling means can be initiated and/or an ablation interrupt means is activated based on pre-determined events.
US09033967B2 Cryotreatment devices and methods of forming conduction blocks
Cryotreatment devices and methods of ablating tissue within the body are disclosed. A cryotreatment device in accordance with an exemplary embodiment of the present invention includes an elongated member having one or more needle-like ablation tips configured to induce necrosis at a target site within the heart. A cooling fluid such as a cryogen may be injected through a lumen extending into the distal portion of the device. The ablation tips can be configured to pierce and ablate surrounding tissue, blocking electrical stimuli that can cause fibrillations or other arrhythmias of the heart. The device may also include means for controlling the transmural depth at which the ablation tips are inserted into the cardiac tissue. Methods of forming a contiguous line of conduction block in accordance with the present invention are also disclosed.
US09033965B2 Nested balloon cryotherapy
A cryotherapy system includes a cryotherapy catheter having an inflatable balloon portion and a pressure regulator. The inflatable balloon portion includes an outer balloon and an inner balloon within the outer balloon. The inner balloon is configured to receive during a cryotherapy procedure a cryogenic agent for extracting heat from body tissue at a desired location. The inflatable balloon portion is at a distal end of the cryotherapy catheter. The pressure regulator is adapted to maintain a positive pressure between the inner balloon and the outer balloon during a cryotherapy procedure.
US09033964B2 Target structure used for generating charged particle beam, method of manufacturing the same and medical appliance using the same
Provided are a target structure used for generating a charged particle beam, a method of manufacturing the same, and a medical appliance using the same. The target structure includes a target layer and a support having a through hole used as a progressing path of a laser beam or a charged particle beam.
US09033961B2 Cardiac ablation catheters for forming overlapping lesions
Methods and instruments are disclosed for creating lesions in tissue, especially cardiac tissue, for treatment of arrhythmias and the like, by employing an elastic balloon and an energy emitter, which is independently positionable within the lumen of the instrument and adapted to project a series of spots of ablative energy through a transmissive region of the balloon to a target tissue site. The energy emitter preferably is configured such the spots of energy result in a series of lesions formed in the target tissue region when the emitter is activated, the lesions having an average area ranging from about 5 mm2 to about 100 mm2. In one aspect of the invention, percutaneous ablation instruments are disclosed in the form of catheter bodies having one or more balloon structures at the distal end region of the instrument and an energy emitting element, which is independently positionable and rotatable within a lumen of the instrument and adapted to project ablative energy through a transmissive region of the balloon to a target tissue site in contact with, or proximal to, the balloon surface.
US09033951B2 Occlusion detection for a fluid infusion device
A device for delivering fluid to a user includes a housing, a drive motor assembly in the housing, a force sensor, and an electronics module. The drive motor assembly regulates delivery of fluid by actuating a piston of a fluid reservoir, and the force sensor generates output levels in response to force imparted thereto during, for example, fluid delivery operations. The electronics module processes the output levels of the force sensor to assess the operating health of the force sensor, to check for occlusions in the fluid delivery path, and to monitor the seating status of the fluid reservoir.
US09033949B2 Needle protection device
A device (2) for bringing a first vessel member (6, 26) in fluid communication with a needle member (4), which device (2) includes an adaptor (20) having a housing (14) with a holding arrangement (16, 18) configured to secure the needle (4) to the housing (14), where the housing (14) has at least a first opening (38, 40) sealed by a seal (10, 12); a cutting device (32, 34) configured to perforate the seal (10, 12). The cutting device (32, 34) is configured to perforate the seal (10, 12) and thereby break the seal (10, 12) by bringing the seal (10, 12) into contact with the cutting device (32, 34) by moving the adaptor (20) towards the vessel member (6, 26) in a manner in which the needle member (4) is not brought into contact with the seal (10, 12).
US09033947B2 Disposable absorbent articles with zones comprising elastomeric components
Absorbent articles having a liquid permeable topsheet, a liquid impermeable backsheet, and an absorbent core disposed between said topsheet and said backsheet are disclosed. The absorbent articles include a thermoplastic elastomer joined to or disposed in a stretch zone on at least one component or region of the absorbent article to impart an elastic resistance that provides sizing or shaping capabilities to the article. The absorbent article can be in the form of diapers, pull-on diapers, training pants, sanitary napkins, wipes, bibs, incontinence briefs or inserts.
US09033943B2 Wound drainage control apparatus
A wound drainage device flow regulator for controlling fluid flow from a wound to a container. The regulator provides selective communication between a conduit and the container. The device includes a valve for communication between the conduit and the container in response to a level of vacuum in the conduit below a selected value. The valve has a diaphragm exposed to atmospheric pressure on one side and to the level of vacuum in the conduit on the other side. A force is applied to the diaphragm in opposition to atmospheric pressure. The difference between the force applied and the force generated by atmospheric pressure provides a control force required to be applied by the level of vacuum in the conduit to close the valve to interrupt communication between container and conduit. A lock mechanism locks the adjustable force mechanism at a desired adjustment corresponding to a desired level of vacuum.
US09033940B2 Eye treatment system with fluidics pump interface
An eye treatment system for performing an ocular surgical procedure contains an eye treatment probe or handpiece, a treatment console, an eye treatment cassette, and a pump formed by the engagement of the treatment cassette with the treatment console. The handpiece is configured to provide at least irrigation fluid to, and aspiration of fluid from, a subject eye. The treatment console comprises a controller configured to control the eye treatment probe. The eye treatment cassette engages the treatment console to couple the eye treatment probe with the treatment console. The pump comprises a pump head having a plurality of projections disposed to rotate about an axis, a ramp disposed near the rotating projections, and a resilient channel configured to transfer fluid when engaged by the ramp and the plurality of projections. The ramp is configured to reduce pressure fluctuations with the eye during a surgical procedure and comprises and entrance portion, a central portion, and an exit portion. The entrance portion has an arcuate extent over which the projections close the channel as the head rotates. The central portion has an arcuate extent over which the channel is sealed by the projections as the head rotates. The exit portion has an arcuate extent over which the projections open the channel as the head rotates. The ramp is configured such that the arcuate extent of the entrance portion is unequal to the arcuate extent of the exit portion.
US09033939B2 Nasal applicator
A nasal applicator for nasally administering medicinal active pharmaceutical substances and/or ingredients, in particular painkillers or analgetics, includes a dosage device for dosedly discharging the active pharmaceutical substance, dosage determining logic for determining the discharged amount of active pharmaceutical substance as well as a locking device for locking the dosage device, in particular when the determined amount of discharged active pharmaceutical substance reaches a predetermined level. The locking device for locking the discharge dosage device is controlled by an electronic control device with a patient data memory into which an individual patient's control data may be inputted via an input device for individually locking the dosage device for a specific patient.
US09033936B2 Medicament delivery device
Medicament delivery device comprising relatively movable housing parts, a medicament container, a proximal plunger rod part and distal plunger rod part in threaded engagement with each other, wherein said proximal plunger rod part is movably arranged in relation to said housing part sand in contact with a stopper of said medicament container, a lever pivotally attached to said housing parts and to the distal plunger rod part. The housing parts are ergonomically shaped having a grip-size for achieving a full hand grip and wherein said distal housing part and said proximal housing part are operably interconnected to each other through said lever such that a relative movement of said housing parts is capable of operating the lever for setting and injecting a dose.
US09033932B2 Medicament delivery device
Provided is a medicament delivery device (100) that is reliable, safe and intuitive to use and at the same time is easy to use when handling. This is achieved by a medicament delivery device (100) comprising a tubular housing (120, 130) having a proximal end (308) and an opposite distal end (309), an actuator member (110) being coaxially arranged at the distal end (309) of the tubular housing (120, 130) and movably arranged, in relation to the tubular housing (120, 130) and a cap (140) being releasably connected to the proximal end (308) of the tubular housing (120, 130) wherein the medicament device (100) further comprises a longitudinal actuator interlocking member (150) movably arranged within the tubular housing (120, 130) and interactively connected to both the actuator member (110) and to the cap (140) for controlling movement of the actuator member (110). Thus the cap (140) acts as a device enabler, i.e. it is impossible to actuate the medicament delivery device (100) until the cap (140) has been removed.
US09033929B2 Fluid removal in a surgical access device
The present invention generally provides methods and devices for removing fluid from a surgical instrument. Surgical access devices and seal systems are generally provided having one or more valves or seal assemblies to create a closed system between the outside environment and the environment in which the surgical access device is being inserted. In one embodiment, a seal assembly is provided and can include a seal having an opening configured to receive a surgical instrument therethrough and a fluid remover in the form of a sorbent element, a scraper element, a wicking element, or any combination thereof can be associated with the seal and configured to remove fluid from the opening and/or a surgical instrument.
US09033924B2 Systems for fluid reservoir retention
A fluid reservoir for use with a fluid infusion device is provided. The fluid reservoir can include a first portion having a first end and a second end. The first end can include an alignment feature and a delivery port. The fluid reservoir can include a second portion coupled to the second end of the first portion, with a portion of the second portion movable within the first portion to advance a fluid out of the delivery port. The fluid reservoir can also include a reservoir defined between the first portion and the second portion that receives the fluid.
US09033920B2 Determining catheter status
A method for monitoring the status of an implanted catheter includes monitoring changes in pressure within a lumen of a catheter associated with physiological parameters (“physiological pressure”) and changes in pressure within the lumen of the catheter associated with bolus infusion of fluid into the catheter or bolus withdrawal of infusion from the catheter (“bolus pressure”). Methods that employ monitoring both physiological pressure and bolus pressure can provide information that cannot be obtained from monitoring physiological pressure or bolus pressure alone.
US09033916B2 Catheter with multi-functional control handle having rotational mechanism
A catheter for use in a patient's heart, especially for mapping a tubular region of the heart, has a catheter body, a deflectable intermediate section and a distal mapping assembly that has a generally circular portion adapted to sit on or in a tubular region of the heart. A control handle of the catheter allows for single-handed manipulation of various control mechanisms that can deflect the intermediate section and contract the mapping assembly by means of a deflection control assembly and a rotational control assembly. The deflection control assembly has a deflection arm and a rocker member. The rotational control assembly has an outer rotational member, an inner rotational member and a cam. A pair of puller members are responsive to the deflection control assembly to bi-directionally deflect the intermediate section. A third puller member is responsive to the rotational control assembly to contract the generally circular portion of the mapping assembly.
US09033913B2 Breastshield unit
A breastshield unit for expressing human breastmilk has a receiving part for receiving a human nipple, an underpressure chamber for applying an under-pressure to the nipple, wherein the receiving part opens into this underpressure chamber, and a membrane for generating an underpressure in the underpressure chamber. The membrane is designed in one or more pieces and at least partially surrounds the receiving part. This breastshield unit permits a separation of media in the area near the breast. It is small and easy to clean and is suitable in particular for use as a hands-free breastshield unit.
US09033912B2 Drug delivery system
A drug delivery device for delivering a drug pellet to a site beneath the skin of a patient is provided, the drug delivery device including a housing having a chamber configured to hold at least one drug pellet, the chamber having a loading end and a delivery end, the loading end of the chamber having an opening for receiving a plunger and a drug pellet and the delivery end having an opening for receiving the plunger and passage of the drug pellet. The housing includes at least one hole substantially perpendicular to the chamber and formed to at least partially intersect the chamber. A capture pin is provided configured to be receivable within the at least one hole.
US09033905B2 Pneumatic compression garment with noise attenuating means
A pneumatic compression garment includes a flexible member for placement on a limb of a human body. A bladder in the flexible member defines an inflatable chamber. The bladder has an opening through which the inflatable chamber is inflated. A port mounted on the bladder has an air inlet adapted for communication with a source of pressurized air and an air outlet in communication with the inflatable chamber via the opening in the bladder. Pressurized air is delivered from into the inflatable chamber for inflating the inflatable chamber and thereby applying a compression force to the limb when the flexible member is in place on the limb. An air diverter affixed to an inside surface of a first sheet of the bladder and configured to divert air entering the inflatable chamber from directly impinging against an inside surface of a second sheet of the bladder.
US09033901B2 System for determining individual user anthropometric characteristics related to mattress preference
A measuring device to aid mattress selection has an upstanding frame with a plurality of vertically space-apart horizontal illuminated strips. A camera mounted in front of the frame takes front view and side view images of a person standing in front of the illuminated strips. These images are delivered to an associated computer having means to determine the body mass distribution and the spine curvature of the person based on the images of the strips taken by the camera and in particular based on those portions of the image of the illuminated strips blocked by the person standing in front of the illuminated strips. This information can then be used to aid in appropriate mattress selection for the person.
US09033899B2 Oral care implement
A toothbrush comprising: a body comprising a handle and a head; a plurality of tooth cleaning elements extending from the head; an oral member coupled to the body, the oral member comprising a water-soluble material; a reservoir in the body; and a fluid pathway in the body, the fluid pathway in fluid communication with the oral member.
US09033897B2 Method for determining the molecular composition of a target tissue or another body structure, and its diagnostic applications
The present invention relates to a sampling instrument adapted for taking a sample in situ and in vivo or taking a sample ex vivo of a target tissue or body structure, in a maximum quantity of less than 10−6 g, the instrument comprising an elongated active member (10) with a distal operative end (11) having at least one retaining surface (12) arranged for contacting directly the target tissue or body structure, capturing and retaining molecules of the target tissue or body structure thereto.
US09033895B2 Endoscope including an torque generation component or torque delivery component disposed within an insertable portion of the endoscope and a surgical cutting assembly insertable within the endoscope
An endoscope for removing tissue at a surgical site includes an elongated tubular body insertable within a mammalian cavity of a patient. An instrument channel extends between a first opening at a distal end and a second opening at a proximal end of the tubular body and is sized and configured to receive a surgical cutting assembly that includes an aspiration channel configured to remove material entering the endoscope via a distal end of the surgical cutting assembly. A torque generation component configured to generate torque is positioned within the distal end and configured to provide the generated torque to a coupling component. The coupling component is positioned at the distal end of the elongated tubular member and configured to actuate a cutting component of the surgical cutting assembly responsive to actuation of the torque generation component.
US09033892B2 Predictive drowsiness alarm method
A method for predicting drowsiness is disclosed. By obtaining average heart beat rate values of a driver, and according to the characteristics of the heart beat rate values over a period of time, the method is utilized to determine whether the human being is going to sleep. The method comprises the following steps: detecting a heart beat rate of a driver; calculating a curve of the heart beat rate average during a time interval of X minutes; determining an accumulated length of duration during which the calculated linear regression slope values are smaller than the predetermined slope value Z; determining whether the accumulated length of duration is greater than a time threshold T to generate a drowsiness detecting result; and determining whether to raise an alarm based on the drowsiness detecting result.
US09033888B2 Ultrasound imaging system using beamforming techniques for phase coherence grating lobe suppression
High-frequency ultrasound imaging can be performed with greater quality and suppressed grating lobes by using methods and systems for effectively reducing the temporal length of transmit grating lobe signals in received ultrasound echoes. Systems and methods are provided for improved high-frequency ultrasound imaging. In various aspects, the method of shortening the time domain of grating lobe signals comprises splitting an array of N transmit elements into K sub-apertures. In further aspects, the grating lobes are suppressed by performing signal processing of the shortened grating lobe signals. In certain aspects, the signal processing method comprises weighting the samples by a calculated phase coherence factor.
US09033887B2 Mitral valve detection for transthoracic echocardiography
A mitral valve is detected in transthoracic echocardiography. The ultrasound transducer is positioned against the chest of the patient rather than being inserted within the patient. While data acquired from such scanning may be noisier or have less resolution, the mitral valve may still be automatically detected. Using both B-mode data representing tissue as well as flow data representing the regurgitant jet, the mitral valve may be detected automatically with a machine-learnt classifier. A series of classifiers may be used, such as determining a position and orientation of a valve region with one classifier, determining a regurgitant orifice with another classifier, and locating mitral valve anatomy with a third classifier. One or more features for some of the classifiers may be calculated based on the orientation of the valve region.
US09033886B2 Ultrasound treatment device
The invention concerns a device for treatment of an organ or tissue of a living being. The device comprises at least one treatment transducer for emission of ultrasound waves, preferably high intensity focused ultrasound (HIFU) waves, focusable on a focal point within or on the surface of said organ or tissue, as well as means for rotating said treatment transducer around an axis which intersects said focal point. The device further comprises synchronization means for synchronizing the rotation of the treatment transducer with at least the emission of ultrasound waves from said treatment transducer and/or an additional imaging transducer.
US09033885B2 System and method for energy delivery to tissue while monitoring position, lesion depth, and wall motion
Systems and methods for ablating tissue include an ablation device having an energy source and a sensor. The energy source provides a beam of energy directable to target tissue, and the sensor senses energy reflected back from the target tissue. The sensor collects various information from the target tissue in order to facilitate adjustment of ablation operating parameters, such as changing power or position of the energy beam. Gap distance between the energy source and target tissue, energy beam incident angle, tissue motion, tissue type, lesion depth, etc. are examples of some of the information that may be collected during the ablation process and used to help control ablation of the tissue.
US09033882B2 Gas supersaturation monitoring
A system and method include generating at least one bubble in tissue using ultrasound. The at least one bubble generated is detected and correlated to gas saturation of the tissue.
US09033877B2 Device and method for determining blood glucose characteristics
A device is provided for determining blood glucose characteristics including a display configured for presenting a graphical representation of a plurality of measurements of blood glucose values, wherein the graphical representation comprises a trend indicator indicating an approximate value trend in the sensed blood glucose value over a recent series of measurements, based on graphical segments having different graphical styles assigned to different ranges of sensed blood glucose values to indicate a transition from a first range to a second range of sensed blood glucose values. An associated method for operating a device for determining blood glucose characteristics is also provided.
US09033876B2 Method and apparatus for deriving and reporting a physiological status of an individual utilizing physiological parameters and user input
Various methods and apparatuses for measuring a state parameter of an individual using signals based on one or more sensors are disclosed. In one embodiment, a first set of signals is used in a first function to determine how a second set of signals is used in one or more second functions to predict the state parameter. In another embodiment, first and second functions are used where the state parameter or an indicator of the state parameter may be obtained from a relationship between the first function and the second function. The state parameter may, for example, include calories consumed or calories burned by the individual. Various methods for making such apparatuses are also disclosed.
US09033872B2 Laparoscopic cannula with suturing capability
A cannula for use in laparoscopic surgery has a central passage which may accept a trocar to create a laparoscopic incision in a body wall to an inner body cavity. A tubular section of the cannula is then pressed into the incision to form a port. After completion of the operation a needle having a blunt distal end with a suture-engaging notch surrounded by a sheath with a sharpened edge is pressed through inclined passages in the side walls of the cannula so as to extend into the body tissue on one side of the cannula and into the body cavity, carrying the suture which is then grasped by an instrument to remove the suture and join it to a needle projecting from the opposite side of the cannula. The needle is then withdrawn so the suture may be knotted on the outer side of the body wall.
US09033871B2 Gravity referenced endoscopic image orientation
An endoscope having a longitudinal axis, a view vector angularly offset from said longitudinal axis, an accelerometer, and an image rotator effectively responsive to said accelerometer, wherein said accelerometer is arranged for measuring rotations about a measurement axis which is generally parallel to said view vector. Through the use of this apparatus, an image is maintained in an upright orientation.
US09033870B2 Pluggable vision module and portable display for endoscopy
Various embodiments for providing removable and pluggable opto-electronic modules for illumination and imaging for endoscopy or borescopy are provided for use with portable display devices. Generally, various medical or industrial devices can include one or more solid state or other compact electro-optic illuminating elements located thereon. Additionally, such opto-electronic modules may include illuminating optics, imaging optics, and/or image capture devices. The illuminating elements may have different wavelengths and can be time-synchronized with an image sensor to illuminate an object for imaging or detecting purpose or other conditioning purpose. The removable opto-electronic modules may be plugged in on the exterior surface of a device, inside the device, deployably coupled to the distal end of the device, or otherwise disposed on the device.
US09033869B2 Cochlear lead
A cochlear lead includes a plurality of electrodes configured to stimulate an auditory nerve from within a cochlea and a flexible body supporting the plurality of electrodes along a length of the flexible body. A stiffening element is slidably encapsulated within the flexible body, the stiffening element extending past a most distal electrode at the tip of the cochlear lead, wherein a distal portion of the stiffening element plastically deforms upon insertion into a curved portion of the cochlea.
US09033868B2 Couplings for interconnecting components of an electro-mechanical surgical device
A flexible shaft includes a flexible, elongated outer sheath, at least one drive shaft disposed within the outer sheath and a moisture sensor disposed within the outer sheath configured to detect moisture within the outer sheath. Another flexible shaft includes a flexible, elongated outer sheath, at least one flexible drive shaft disposed within the outer sheath and a coupling connected to a distal end of the outer sheath configured to couple to a surgical attachment.A sleeve includes an elongated shaft configured to receive a flexible shaft therein and a securing arrangement configured to selectively and variably retain the elongated shaft in any one of a number of longitudinal positions along the flexible shaft.A surgical system includes an electro-mechanical driver, an elongated, flexible sheath, at least one drive shaft disposed within the flexible sheath, a surgical attachment coupled to the at least one drive shaft, the electro-mechanical driver configured to drive the surgical attachment, a shape-retaining sleeve, at least a portion of the flexible sleeve being disposed in the shape-retaining sleeve, the shape-retaining sleeve configured to maintain the at least portion of the flexible sheath in a predetermined shape, and an arrangement variably securing the shape-retaining member to the flexible sheath in any one of a number of longitudinal positions along the flexible sheath.
US09033865B2 Treatment tool for endoscope
A treatment tool for an endoscope including: an insertion section inserted from a mouth ring provided at the base-end portion of a channel of the endoscope to the inside of the channel; an operation section provided at the base end of the insertion section; a rigid guide member having a tubular shape, externally fitted around the insertion section at the base end of the insertion section, and fixed to the operation section; and a fixing section that is externally fitted around the guide member, firmly attaches between the inner wall of the mouth ring or the channel and the guide member, and fixes the guide member to the inner wall of the mouth ring or the channel.
US09033859B2 Method and device for determining a radiotherapy treatment plan
A radiotherapy treatment plan for irradiation of an object to be irradiated is determined. The object to be irradiated includes a number of irradiation areas and the object to be irradiated is irradiated with a number of beams from different directions. The method includes determining a number of total dose conditions. One of the number of total dose conditions is assigned to a respective one of the number of irradiation areas. The method further includes determining a number of single beam dose conditions. One of the single dose conditions is assigned to a respective one of the number of beams and a respective one of the number of irradiation areas. The method also includes determining irradiation parameters for the number of beams as a function of the number of total dose conditions and the number of single beam dose conditions.
US09033857B2 Apparatus and method for continuous microfolding of sheet materials
A machine (10) and method for the continuous folding of sheet material (15) into difference three-dimensional patterns is featured. The innovative machine and method folds sheet material by force converging the sheet to a final stage that imparts a final fold or pattern. Unique programming allows for the change of convergence sequencing and change of materials. A plain die fold multiplier is placed before the final stage to double the number of folds in the sheet material and halve the height thereof.
US09033851B2 Motor drive assembly for a vehicle and a motor vehicle
A motor drive assembly can prevent a two-way roller clutch of the current speed ratio and a two-way roller clutch of the next speed ratio from engaging simultaneously, and includes a first-speed friction plate formed with engaging protrusions on the first-speed side, and a shift ring formed with engaging recesses. While the shift ring is in a first-speed shift position SP1f, the engaging protrusions are adapted to be engaged in the engaging recesses, thereby preventing rotation of the shift ring relative to the first-speed friction plate. The shift ring is provided with projections on its inner periphery. The drive assembly further includes an annular protrusion formed with cutouts. When the projections are axially and circumferentially displaced from the respective cutouts, the projections are adapted to interfere with the annular protrusion, thereby preventing axial movement of the shift ring between the first-speed shift position SP1f and a second-speed shift position SP2f.
US09033849B2 Backlash-free planetary gear unit with planet carriers preloaded relative to each other
The invention relates to a backlash-free planetary gear unit with a sun gear and with a ring gear, which mesh with at least one first planet gear of a planetary stage, wherein the planetary stage comprises a first planet carrier on which the first planet gear is rotatably mounted, wherein there is furthermore at least one second planet gear in the planetary stage that also meshes with the ring gear and the sun gear, wherein the at least one second planet gear is rotatably supported at a second planet carrier of the planetary stage, wherein the two planet carriers are in the circumferential direction of the sun gear preloaded relative to each another such that also the at least one first planet gear is preloaded relative to the at least one second planet gear in the circumferential direction of the sun gear.
US09033847B2 Automatic transmission
An automatic transmission (11) includes a planetary gear set (PS), first to third clutches (C-1 to C-3), first to third brakes (B-1 to B-3), and a counter gear (100) that outputs shifted rotation. The counter gear (100) is placed axially on one side of the planetary gear set (PS), and the second brake (B-2) is placed axially on the opposite side from of the counter gear (100) from the planetary gear set (PS). The second brake (B-2) that does not make higher speed rotation than other clutches and brakes can thus be separated from the planetary gear set (PS), and other clutches and brakes and the counter gear (100) are arranged near the planetary gear set (PS). Thus, members having a large thickness are reduced in length, whereby the automatic transmission is made compact and reduced in weight.
US09033837B2 Planetary gear for transmitting a driving torque in a vehicle, and drive unit comprising the planetary gear
A planetary gear and a drive unit having the planetary gear, the planetary gear being characterized by very good integratability. For this purpose, a planetary gear (5) for transmitting a drive torque in a vehicle is proposed, having a first sun wheel attachment (12a) and a second sun wheel attachment (12b), each of the sun wheel attachments (12a, b) being coupled to a shaft (2a, b) in a rotationally fixed manner, and the sun wheel attachments (12a, b) being rotatable relative to one another, and the sun wheel attachments (12a, b) being situated in an overlapping area (11), overlapping in the radial direction.
US09033835B2 Sprocket
The invention relates to a multipart sprocket (1), in which an inner ring (2) for fixing the multipart sprocket (1) to a wheel hub comprises through-holes (5) which are located on a common hole circle, wherein the inner ring (2) on the periphery thereof comprises radially outwardly directed inner ring lugs (2A) for receiving a gear rim (8), and the gear rim (8) comprises radially inwardly directed gear rim lugs (11) which are spatially associated with the radially outwardly directed inner ring lugs (2A), and means (12, 13, 14) are present, which connect the inner ring (2) and the gear rim (8) axially and radially.
US09033831B2 Belt-driven continuously variable transmission
A belt-driven continuously variable transmission having a downsized torque cam assembly for creating forward thrust to push a movable sheave toward a fixed sheave.The belt-driven continuously variable transmission is adapted to output a torque while changing a speed ratio continuously by altering an effective diameter position of a driving belt. The belt-driven continuously variable transmission is comprised of: an output gear, which is fitted onto the rotary shaft of the driven pulley to output the torque while being allowed to rotate relatively; a piston, which is fitted onto the rotary shaft of the driven pulley between the movable sheave and the output gear while being allowed to rotate integrally with the movable sheave and to reciprocate in an axial direction of the rotary shaft, and which increases an internal pressure of the hydraulic chamber by moving toward the movable sheave; and a torque cam assembly, which is interposed between the piston and the output gear, and which pushes the piston toward the movable sheave when the torque transmitted through the driven pulley is increased.
US09033825B2 Golf ball having an aerodynamic coating including micro surface roughness
Golf balls include: (a) a golf ball having a first set of construction specifications; (b) a coating of the golf ball having an exterior surface and (c) the exterior surface having an enhanced micro surface roughness. The enhanced micro surface roughening affects the aerodynamic properties of the ball as compared to golf balls having the same set of construction specifications but without enhanced micro surface roughness.
US09033824B2 Golf ball
A golf ball of the present invention includes: a core located in the center of the golf ball; a cover surrounding the outside of the core and having plural dimples on the surface thereof; and a paint layer surrounding the outside of the cover. The paint layer is formed of a material having rubber elasticity. When the golf ball has a μ hardness and the paint layer has a JIS-C hardness, a ratio Sp of the JIS-C hardness of the paint layer with respect to the μ hardness of the golf ball is at most approximately 15. When the cover has a Shore D hardness, a ratio Sc of the Shore D hardness of the cover with respect to the μ hardness of the golf ball may be at most approximately 25.
US09033820B2 Golf club head
A golf club head of the present invention includes a face. The face has a score line groove, a fine groove, and a land area. A depth of the fine groove is 0.01 mm or greater and less than 0.03 mm. A width of the fine groove is 0.1 mm or greater and 0.3 mm or less. A pitch of the fine groove is 0.3 mm or greater and 0.7 mm or less. Preferably, the face further has a protruding part protruding beyond the land area. Preferably, the protruding part is provided on a top blade side of the fine groove. Preferably, the protruding part extends along the fine groove.
US09033819B2 Golf club head with face insert
A golf club head is provided having a club body and a contact plate secured to the club body. The contact plate defines at least a portion of a striking surface having a plurality of striking surface grooves. The contact plate is formed using an electroforming process.
US09033818B2 Golf club head having a multi-material face
A golf club head with a multi-material face is disclosed herein. The layers of the multi-material face are preferably attached to the club head using adhesive and mechanical methods.
US09033817B2 Golf club irons including backing material behind ball striking face
Golf clubs and golf club heads, such as iron heads, may include an iron body and a ball striking plate engaged with the iron body. The ball striking plate may include a face layer and a backing layer. The face layer of the ball striking plate may be formed of a metal material, while the backing layer may be formed of a polymeric material. The backing layer isolates the face layer from the iron body. In some arrangements, the backing layer of the insert may be visible at the top, the bottom, the side and/or the front surfaces of the iron head. Methods for making such iron devices are also described.
US09033816B2 Hybrid golf shaft
Disclosed a hybrid golf shaft in which one or more aramid fiber containing prepregs (H) are laminated in a length section of 5 cm or more of the whole length of the golf shaft, and three or more carbon fiber prepregs (C) are laminated in a length section of 50 cm or more of the whole length of the golf shaft. The golf shaft is configured in that aramid prepregs (H1) or hybrid prepregs (H2) with excellent impact absorbability are arranged in a length section of 5 to 50 cm from a thin end of the golf shaft or along the whole length (L) in an axial direction of the golf shaft, to thereby effectively reduce the number of vibrations in the golf shaft when the golf ball is hit.
US09033815B2 Adjustable golf club and system and associated golf club heads and shafts
In general, aspects of this invention relate to golf clubs or golf club components incorporating adjustment members that permit ready adjustability of golf club parameters and/or interchangeability of golf club components to change a golf club configuration, and methods for providing golf clubs. According to aspects of this invention, an adjustment member may be utilized to allow the adjustability of a golf club parameter to change a golf club configuration, while ensuring there is substantially no change to other club or club head variables, parameters or characteristics. According to another aspect of this invention, an adjustment member may be utilized to allow the adjustability of two golf club parameters independently to change a golf club configuration, while ensuring there is substantially no change to other club or club head variables, parameters or characteristics.
US09033809B2 Child swing apparatus
A child swing apparatus can include a support frame, a seat support for receiving the placement of a child, a swing arm assembled with the support frame about a pivot axis, the swing arm holding the seat support, a driven part arranged radially spaced apart from the pivot axis and movable with the seat support and the swing arm relative to the support frame, and a drive mechanism assembled with the support frame, wherein the drive mechanism has a driving end operable to apply a torque on the driven part to cause swing motion of the seat support.
US09033808B1 Teeter totter apparatus
A teeter totter apparatus comprises a base portion, a caster assembly including a caster base portion having a plurality of caster base holes for fixing the caster base portion to the base portion, and a caster yoke portion rotationally coupled with the caster base portion allowing rotation of the caster yolk portion about a first axis. A beam portion coupled with the caster yolk portion includes at least one seating portion and is capable of being fixed to the caster yolk portion while allowing the beam portion to rotate about a second axis. In another aspect, a teeter totter apparatus includes a seating portion and opposing seat adjustment portion that sandwich the beam and allow the seat portion to be adjusted in position along the beam. In another aspect, a lazy Susan rotational bearing coupled between the base and yolk portions provides the rotational capabilities for the apparatus.
US09033806B2 Gaming machine
Described herein is a gaming machine (12) including a cabinet (12) having an upper portion (14) and a lower portion (16). A primary display (18) is disposed in the upper portion and a user interface (20) is disposed in the lower portion. The maximum frontal width of the lower portion is substantially less than the maximum frontal width of the upper portion such that a clearance is defined under the upper portion on each side of the lower portion.
US09033805B2 Three dimensional operations in an isometric projection
A system, computer-readable storage medium storing at least one program, and a computer-implemented method for providing three-dimensional operations in an isometric projection are presented. A graphical user interface may be presented to a user that presents an isometric projection of a virtual environment. A placement event corresponding to a user initiating a placement of a game object within the virtual environment may then be detected. The game object may be modeled with a two-dimensional model. Selection coordinates associated with the placement event are then obtained. Using the selection coordinates, it may be determined that the user selected one of a plurality of surface areas of an existing game object. Then, the game object is then inserted within the virtual environment relative to the one of the plurality of surface areas of the existing game object.
US09033803B1 Changing a virtual world based on real-world locations of players
A method of changing a virtual world of a computer-implemented game based on real-world locations of players of the computer-implemented game is disclosed. A presence of a player of the computer-implemented game is detected at a physical location. A presence of an additional player of the computer-implemented game is detected at the physical location based on a communication received from the player of the computer-implemented game. An aspect of the virtual world of the computer-implemented game is changed based on the detecting of the presence of the player at the physical location and the detecting of the presence of the additional player of the computer-implemented game at the physical location.
US09033800B2 Gaming machine
A gaming machine with more gaming excitement is provided. The gaming machine includes: a cabinet; an upper image display panel which is provided on the cabinet and displays an effect image concerning a game; a lamp body unit which includes a lamp body which is a formed object and a sensor configured to detect the player's gesture with respect to the lamp body and is provided at a position different from the upper image display panel when viewed from the front surface of the cabinet; and a controller used to start the game, and the controller detects the player's gesture by the sensor at a timing corresponding to the state of the game and displays an effect image corresponding to the detected player's gesture on the upper image display panel.
US09033799B2 Synchronizing audio in a bank of gaming machines
Systems and methods for synchronizing audio in a bank of gaming machines, such as video slot and video poker machines. Audio tracks of a game may be provided to a plurality of gaming machines and synchronized. An audio track provided to one of the gaming machines may be changed to a second audio track, in response to receiving an indication of a status change for the game. The second audio track may be synchronized with the audio tracks provided to the other gaming machines in the plurality.
US09033796B2 Automatic movement of player character in network game
A player participating in a network game moves a player character of the player by manipulating a video game apparatus of the player. As the player performs an autopilot operation, the video game apparatus moves the player character as an autopilot PC. A server apparatus manages the game which progresses according to the movement of each character, and transmits progress information of the game to the video game apparatus of each player participating in the network game. The movement of the autopilot PC is decided based on an action log recording the action of the player character responding to the manipulation of the player.
US09033794B2 Method and apparatus for providing secure and anonymous cash-out and cash-in values in a gaming system
A method, apparatus, article of manufacture, and a memory structure for providing a payout to a player is disclosed. An ATM or ATM-like device is used to cash out of and cash into gaming devices with the player's fingerprint used to securely transfer the cash-in or cash-out data between the gaming device and the ATM. An embodiment is disclosed in which the information is passed between the ATM and the gaming device via a token.
US09033783B1 Methods and systems of enabling users to actively allocate advertising resources and promote follower tracking
The present invention provides a system that allows users to directly participate in advertising resource allocation decisions for advertisers and to actively cause navigation swarms to specific websites. Swarms of users can be enabled by playing a form of hide and seek, where users (hiders) actively hide at a specific network location (the place where a swarm is desired) and other users (seekers) then actively search for the hiding users, thereby creating a swarm effect toward a particular site or set of sites.
US09033782B2 Sensing ball game machine
A sensing baseball game apparatus (10) has a game machine (12) connected to a television monitor (18). A bat input device (32) is provided with an acceleration sensor. An acceleration signal is transmitted by an infrared-ray LED (34) to an infrared-ray receiving part of the game machine (12) whereby the game machine (12) determines a moving speed of the bat input device (32) to calculate a moving parameter of a ball to be batted. Accordingly, a batted ball is moved in the game scene according to the parameter.
US09033779B2 Air diverter for a cleaning system of a combine harvester
A cleaning system for a combine harvester that includes a cleaning shoe having a sieve, a cleaning fan, an air plenum and a pair of air diverters is provided. The cleaning fan is rotatably driven for generating a flow of air and positioned within the air plenum. The air plenum extends across the entire length of the cleaning fan and includes an inlet for the intake of air, an outlet downstream the inlet for directing the flow of air in a first direction, lateral walls forming a portion of the outlet, and a bottom wall extending between the lateral walls. The pair of air diverters extends inwardly from the lateral walls. Each air diverter is configured substantially as a pyramid having a rounded corner that extends inwardly from the lateral wall and upwardly from the bottom wall.
US09033775B2 Cam and lever assembly
A cam and lever system comprising a cam having a side perpendicular to an axis of rotation of the cam and a channel on the side of the cam, the channel having a bottom wherein the channel is at least partially defined by a first wall and a second wall that diverge as the distance from the bottom increases, a lever, having a pin extending into the channel and an axis of rotation that is generally parallel to the axis of rotation of the cam, and having a configuration sufficient to provide point contact with the walls of the channel.
US09033772B2 Method for producing frozen oysters on the half shell
A method for producing frozen oysters on the half shell, which comprises the steps of freezing live oysters in their shells, so that the oysters hinges will break open; subjecting the frozen oysters to a water treatment to promote disengagement of the oysters' flesh from one thin shell; and percussing the water treated oysters, so that at least one shell will be knocked off.
US09033768B2 Method and device for machining shafts
The invention relates to a device (1) for machining a stepped shaft (2), having a workpiece rest (6); having a disk arrangement (3) which has a grinding disk (4) and a control disk (5); and having an axial stop arrangement (7), wherein the axial stop arrangement (7) has a contact adapter (8) which can be temporarily placed in contact with an end surface portion (9) of the shaft (2) and which has a punctiform contact surface (10) for contact against a stop part (11) of the stop arrangement (7).
US09033766B2 Tool for selective honing of a cylinders outer-diameter
A tool is disclosed for selective honing of the outer diameter of a cylinder using an abrasive belt in semi-circular contact upon the outer-diameter of a cylindrical work-piece to perform a similar function to honing the inner-diameter of a hollow cylinder. The belt is retained within the tool body by U-shaped restraint arms, and a slot in the tool body. A clamp block retains the ends of the belt which exit the slot. Springs on the arms, and contact of the block on the outside of the tool body, force the belt into a triangular shape inside the body. A cylindrical work-piece inserted within the triangular shaped belt causes the belt to deform into three semi-circular areas of contact between the belt and work-piece. When the work-piece is rotated, the belt abrades material from the work-piece.
US09033762B2 Method and device for preventing slip of work piece
A master servo motor and a slave servo motor that synchronously drive for rotation a master main spindle provided with a center that supports one end of a work piece and a slave main spindle provided with a center that supports the other end of the work piece are included. Before grinding, a slip detection cycle that detects a limit current value for the servo motors, at which the work piece and the centers slip, is executed and, during grinding, a grinding condition is changed to prevent a slip between the work piece and the centers in advance at the time when any one of current values of the servo motors has reached a slip threshold value set on the basis of the limit current value.
US09033759B2 Convertible headgear
Headgear that can be converted into another object, comprising a figurine provided with a hollow base which, in at least one configuration, defines an object including a volume for receiving an element. In a second configuration, the hollow base can be turned partially inside out to form a second object including another reception volume and, in a third configuration, the hollow base can be turned fully inside out to form a third object.
US09033757B2 Method of fabricating lightweight and thin liquid crystal display
In a method for fabricating a lightweight and thin liquid crystal display (LCD), a first mother substrate, a subsidiary substrate and a thin second mother substrate are provided. An edge cut is formed by cutting edges of the first and second mother substrates and the subsidiary substrate to be inclined at a predetermined angle. An array process is performed on the first mother substrate. The subsidiary substrate is attached to the second mother substrate. A color filter process is performed on the second mother substrate having the subsidiary substrate attached thereto. The first and second mother substrates are attached together. The subsidiary substrate is separated from the first and second substrates by spraying air between the second mother substrate and the subsidiary substrate, in which the edge cut is formed.
US09033755B2 Lifejacket provided with heating unit
A life jacket provided with a heating unit, capable of preventing a person wearing the life jacket from dying due to hypothermia after the person has fallen into water. The life jacket provided with a jacket main body in which a space is formed between an inner skin and an outer skin, and a floater and a heating unit which are inserted into the space of the jacket's main body includes: a heating portion for producing heat by contacting water; a water transferring member, one end of which arranged within the heating part and the other end of which exposed to a surface of the jacket's main body so that water infiltrates thereto from the other end by capillary action and permeated into the heating part; and a covering part attached on a surface of the main body of the jacket covering the other end of the water transferring member.
US09033754B2 Releasable binding systems
A releasable water ski binding system includes a trigger mechanism that causes releasable bindings to release a boot from a ski. The trigger mechanism senses a displacement of a portion of a body of a skier past a point of criticality and causes the releasable bindings to release the boot from the ski.
US09033752B2 Suspension device for outboard motor, vessel propulsion apparatus, and vessel
A swivel bracket is coupled via a horizontal bracket to a clamp bracket to be mounted on a vessel. A trim mechanism adjusts a trim angle of an outboard motor by rotating the swivel bracket about the horizontal shaft. The trim mechanism includes a trim cylinder coupled to the clamp bracket and a trim rod that is projectable and retractable from the trim cylinder. A thrust receiver is attached to the swivel bracket. The thrust receiver receives a load from the trim rod. The thrust receiver is grounded. The thrust receiver includes a conducting portion in contact with the trim rod.
US09033751B2 Connector terminal
In a connector terminal connected to an electric wire in which a conductor is covered with an outer cover, the terminal includes a barrel portion that is exposed from the outer cover and is to be crimped to the conductor coated with a covering, and an electrical connection portion electrically connected to a mating terminal, wherein a trench or a projection that is provided along a direction perpendicular to an axis of the electric wire are formed in an inner surface of the barrel portion, and a depth of the trench or a projecting dimension of the projection is made smaller than a covering thickness of the covering.
US09033747B2 Connector
A connector includes an inner plate including cavities for holding terminals connected to electric wires, a cylindrical housing which accommodates therein the inner plate, and a filling material which is filled in an interior of the housing so as to surround a periphery of the inner plate. A plurality of air bleeding holes are formed in a portion of the inner plate other than portions where the cavities are provided so as to penetrate from a front side to a back side thereof.
US09033746B1 Rail-based fastening structure for terminal block
A rail-based fastening structure for terminal blocks includes a fastening clip, a positioning rail and a bus body. The fastening clip has a base plate and two side plates each extending upward from the base plate and having an engaging hook. The positioning rail includes a bottom plate and two tracks extending upward and then outward from two opposite sides of the bottom plate, so that the bottom plate and the tracks define a valley. The bottom plate has an opening. The bus body deposited in the valley has a slot and two shoulder portions. The shoulder portions are positioned at two sides of the slot and extend toward the slot. The fastening clip is inserted into the opening through the slot so that the engaging hooks engage with the shoulder portions, respectively. Thereby, the rail-based fastening structure allows quick and convenient mounting/dismounting operation, low manufacturing costs and firm installation.
US09033743B2 Electric connection terminal and connector including the same
When a second junction portion of a terminal is pressed in the opposite direction of the direction of contact with a mating terminal, a first junction portion attempts to be displaced relatively in the direction of contact with the mating terminal as compared to the second junction portion while in a of state contact with the mating terminal, and accordingly, contact pressure of the first junction portion as to the mating terminal increases. Thus, after the mating terminal comes into contact with the first junction portion, contact pressure of the first junction portion as to the mating terminal is not reduced even when the mating terminal comes into contact with the second junction portion.
US09033742B2 Connector and illumination device
A connector (27) is adapted to be connected to a circuit board (23) and has an insulating housing (41) adapted to be mounted to one end portion of the circuit board. The housing is provided with conductive contacts (42) each having a shape along the housing. The housing has first and second portions (51, 52) that respectively face both surfaces of the circuit board when the housing is mounted to the circuit board, and a joining portion (54) joining the first and second portions together. The contacts are insulated from the circuit board in the joining portion and are exposed in the first portion so as to be capable of contacting the surface of the circuit board.
US09033732B2 Coaxial connector and connector unit
A coaxial connector is adapted to hold a connection object having a ground conductor and a signal conductor and is adapted to be fitted to a mating connector. The coaxial connector has a shell for holding the connection object. The shell comprises a first shell portion having a barrel-shaped shell contact portion, a second shell portion having shell connecting portions, positioning portions for positioning the connection object so that a contact portion of the signal conductor of the connection object is located inside the barrel-shaped shell contact portion as seen in a fitting direction of the coaxial connector and the mating connector, and fixing portions for fixing the connection object.
US09033728B2 Telecommunications patch panel with angled connector modules
A telecommunications patch panel is provided having a plurality of connector modules rotatably mounted to a frame member. Each connector module has a front face and an opposite facing rear face, and each front face includes a plurality of connector jacks. Each rear face includes a plurality of wire termination blocks. The wire termination blocks are electrically connected to the connector jacks. Each connector module is rotatable about a rotation axis relative to the frame member. A lock selectively locks each connector module to the frame member as desired. The connector jacks and the connector modules are arranged in linear arrays perpendicular to the axis of rotation.
US09033726B2 Systems for establishing electrical interconnections for helmet-mounted devices
Systems for establishing electrical interconnections for helmet-mounted devices are disclosed. A system for establishing an electrical interconnection for a helmet-mounted device is comprises a first interconnect mechanism coupled to one of a helmet and the helmet-mounted device, and a second interconnect mechanism coupled to the other one of the helmet and the helmet-mounted device. The first interconnect mechanism comprises a first frame, a biasing member, a plurality of first electrical contacts, and a first projection. The second interconnect mechanism comprises a second frame, a plurality of second electrical contacts, and a second projection. As the first interconnect mechanism is moved toward the second interconnect mechanism, the contact between the first projection and the second projection causes rotation of the first frame in a direction opposite the predetermined rotational direction.
US09033725B2 GG45 plug with hinging load bar
A communication plug is described. The communication plug can have a load bar, housing, and a divider. The load bar has a first half with first conductor receiving apertures and a second half with second conductor receiving apertures with a hinge connecting the first half and the second half. The load bar folds around the divider and then is inserted into the housing.
US09033723B2 High voltage connector
A high voltage connector is provided that includes a female body, a male body, and a safety pin. The female body has an insertion bore, a push bar, and an engagement portion. The male body is inserted in the female body. An upper end portion of the male body has an engagement hook positioned to correspond to the engagement portion to engage the engagement hook and the engagement portion when the male body is inserted into the insertion bore of the female body. In addition, a first side of the safety pin is inserted in an upper portion of the insertion bore in the female body and contacts first sides of the engagement portion and the engagement hook. A second side of the safety pin is exposed and has a pin recess into which a removal tool is to be inserted.
US09033722B2 Electric connection terminal and connector including the same
When a second junction portion of a terminal is pressed in the opposite direction of the direction of contact with a mating terminal, a first junction portion attempts to be displaced relatively in the direction of contact with the mating terminal as compared to the second junction portion while in a of state contact with the mating terminal, and accordingly, contact pressure of the first junction portion as to the mating terminal increases. Thus, after the mating terminal comes into contact with the first junction portion, contact pressure of the first junction portion as to the mating terminal is not reduced even when the mating terminal comes into contact with the second junction portion.
US09033720B2 Lever-fitting-type connector
Lever-falling prevention walls configured to prevent a pair of arm plates of a lever from falling to an inner side are provided on a collar-like plate portion of a hood to protrude in a same direction as a pair of support wall portions protrudes.
US09033716B2 Printed circuit board connectors
Contact pads on structures such as printed circuits may be coupled to each other using printed circuit connectors such as board-to-board connectors. A printed circuit connector may have interlocking metal frame structures. The metal frame structures may be soldered to traces on the printed circuits. Rectangular openings in the metal frame structures may receive a rectangular contact array structure that is separate from the metal frame structures. The contact array structure may include a dielectric carrier structure and an array of conductive contacts. The dielectric carrier structure may align the contacts with respect to pads on the printed circuits to which the metal frame structures are soldered. The contacts may be formed from metal spring structures or conductive elastomeric structures that are compressed between respective printed circuit contact pads when the metal frame structures of a printed circuit connector are attached to each other.
US09033715B2 Inter-board connection terminal and inverter and electric compressor employing the same
Provided are an inter-board connection terminal with which electrical connection between two boards can be simplified, the operability and productivity thereof can be enhanced, and reliability of electrical connection can also be ensured, as well as an inverter and an electric compressor employing the same. An inter-board connection terminal includes a group of numerous metal terminals which is inserted, individually at both tips thereof, into through-holes in boards to electrically connect two boards, wherein paired resin linking members are provided, which have a predetermined space therebetween with respect to the group of metal terminals and which join the group of metal terminals into a single unit by linking the terminals in the form of a row at both tips thereof near the bases of portions to be inserted into the through-holes in the boards.
US09033708B2 Implant-supported braced dental bridge armature made from composite material, and method for manufacturing the armature
A dental bridge armature designed to be screw-fastened onto dental implants, the dental bridge armature having reinforcing elements formed by long fibers pre-impregnated with photo-polymerizable resin which are either woven or in bundles. The reinforcing elements are in the form of a fibrous framework including a main brace and base reinforcing elements wound around a series of implant abutments screwed onto the implants. Secondary braces are also wound around the main brace and the base reinforcing elements. The braces form an angle between 15° and 85° with the base reinforcing elements. The armature is then included in a PMMA coating resin by a pressing or injection technique.
US09033706B2 Wireless recharger of complete melting type for endodontic treatment
A complete melting type cordless filling instrument for endodontic treatment is disclosed which uses a switching circuit, to be operable using a miniature dry battery for supplying DC power. The filling instrument includes a body with a battery for supplying DC power, a heater at a front end of the body to heat and melt gutta-percha, an injector mounted to the body in front of the heater to discharge the melted gutta-percha, a charging part provided at the body to charge the gutta-percha in the body, a feeding member which feeds the gutta-percha charged in the body, a filling switch which turns on the heater, and a control circuit installed in the body, to control a temperature of the heating core and an operation of the heating core. The control circuit includes the filling switch, and a switching circuit adapted to efficiently maintain electrical energy supplied from the battery.
US09033702B2 Gas burner
The present invention relates to a gas burner in which a burner body and a side plate are assembled together without a welding process, to thereby simplify manufacturing procedures and reduce manufacturing costs. To accomplish this, the gas burner of the present invention includes a plurality of burner units (110), each of which has a burner body (111) with a main flame being formed at the top thereof, a side plate (112) which forms auxiliary flame holes (116) in the spaces between both side surfaces of the burner body (111) and the side plate (112), and a plurality of supports (113, 114) protruding from the side plate (112). Both ends of each of the burner units (110) are supported by first and second brackets (200a, 200b), respectively. The supports (113, 114) formed at the side plate (112) of the burner unit are brought into contact with and are supported by supports (123, 124) formed at a side plate (122) of an adjacent burner unit (120).
US09033700B2 Apparatus and method for cleaning regenerative-burner media bed
A regenerative burner device for a furnace and a method of removing contaminants from such a device. The burner device includes a burner for introducing heat and waste gas into a furnace during ignition when supplied with fuel and a combustion gas, a media bed comprising refractory particles, and ducting for delivering combustion gas to said burner during ignition, and for drawing waste gas from said furnace on termination of ignition. The ducting causes the combustion gas and the waste gas to pass in succession through the media bed. Means are provided for periodically delivering a rapid flow of a decontaminating gas into said media bed. The rapid flow is of sufficient force to dislodge contaminants collected in the media bed from said waste gas.
US09033693B2 Unitary elastic mold and cutter combination
A unitary elastic mold and cutter combination configured to mold and cut moldable material is disclosed herein. The mold and cutter combination comprises an elastic mold cavity having an elastic bottom wall with an embossed inner surface and an elastic sidewall extending from and unitary with a perimeter of the bottom wall. An elastic cutting blade extends from and is unitary with the sidewall of the mold cavity and is configured to cut moldable material and maintain a substantially consistent perimeter upon cutting. The cutting blade comprises a cutting edge disposed between an inner cutting blade surface and an outer cutting blade surface. The mold and cutter combination may have an elasticity sufficient to release molded material therefrom by hand stretching, wherein the cutting edge, inner cutting blade surface, and the inner surface of the sidewall of the mold cavity are stretched by an amount sufficient to release the molded material.
US09033688B2 Hydraulically powered ball valve lift apparatus and method for downhole pump travelling valves
The Invention provided is a hydraulic powered down hole reciprocating pump traveling valve component to provided lifting hydraulics on the down stroke using the derived motion and pressure of petroleum liquids and gasses, such as oil, water and natural gas and also utilizing the frictional traveling forces driven by the surface equipment. Designed to utilize the elements within the pumping apparatus to obtain the hydraulic power within and transfer the energy's force to the exposed bottom end of the pressure locked traveling ball valve adjacent within the ball valve containment cage, providing ultimate lifting power to open the ball valve on the initiation of the down stroke. The component consist of a Hollow Hydraulic Power Shaft, Hollow Pressure Motion House, and a Fluid Cavity Power Drag Plunger.
US09033687B2 Hose pump with planetary gear
The invention relates to a hose pump for delivering a medium conveyed through a hose, including a housing, a drive, a carrier rotatable with respect to the housing, and a plurality of squeeze rollers that are mounted rotatably on the carrier and can be driven by the drive via a gear with a sun wheel and with a first planet wheel connected so as to rotate with the respective squeeze roller, wherein rotating squeeze rollers, during operation of the pump, press a hose, which is inserted into the pump, by squeezing the hose against an abutment and in this way convey the medium onwards through the hose in the delivery direction. In order to permit easier and quicker insertion of a hose in such a hose pump, the invention proposes that, in addition to the first planet wheel, each squeeze roller is also assigned at least a second planet wheel, which is coupled to the inner circumference, acting as a hollow wheel, of the housing in order to set the carrier in rotation from the drive during operation of the pump.
US09033683B2 Valve, fluid control device
In a fluid control device, a check valve includes a first valve housing and a first diaphragm. The first diaphragm defines a first valve chamber and a second valve chamber. An exhaust valve includes a second valve housing and a second diaphragm. The second diaphragm defines a third valve chamber and a fourth valve chamber. The check valve is opened and closed by a difference in pressure between the first valve chamber and the second valve chamber. The exhaust valve is opened and closed by a difference in pressure between the third valve chamber and the fourth valve chamber.
US09033680B2 Electric fan
An electric fan is provided, including a labyrinth structure with increased performance of preventing entry of a liquid into a receiving space to receive a stator and a rotor. A clearance is defined between an opposed wall portion of a base and an opposed wall portion of an impeller body, which are opposed to each other in an axial direction of a rotary shaft, to form a labyrinth structure. The opposed wall portion of the base and the opposed wall portions of the impeller body are shaped to form a volume expanding portion within the clearance. The volume expanding portion is constituted from a groove portion for expanding the clearance, having a volume larger than other portions within the clearance.
US09033679B2 Displacement control system for variable displacement compressor
A displacement control system (A) of a variable displacement compressor sets a target for pressure in an intake chamber or a crank chamber, on the basis of a detected evaporator-outlet air temperature and a target for evaporator-outlet air temperature. The pressure of a refrigerant in a high-pressure section is detected, and a regulating current is supplied to a solenoid (316) of a displacement control valve, on the basis of the pressure of the refrigerant in the high-pressure section and the target for pressure.
US09033678B2 Air pump having an auto-stop control device
An air pump includes a casing, a blower connected with a motor, an air flow direction switching device, an air valve, and an auto-stop control device. The air flow direction switching device includes a pressure sensor and a pressure switch. The air flow direction switching device includes a movable box and a driving device which drives the movable box. The movable box has an arm and an activation portion. An inflation switch and a deflation switch are electrically connected in parallel to a circuit and are controlled to activate by the activation portion. The pressure switch includes a dynamic contact point connected to the motor, and two static contact points respectively electrically connected to the inflation switch and the deflation switch. The dynamic contact point has a terminal which alternatively contacts the two static contact points.
US09033677B2 Fire hose adapter and method of use
A fire hose adapter comprising a body and a vacuum generator. The body having a cap and a hose connector. The cap being penetrated by a generator channel that connects an intake port with an exhaust port, the two ports being located on an exterior of the cap. The hose connector defining a vacuum channel that continuously connects the generator channel to a vacuum aperture located on an exterior of the hose connector. The vacuum generator being located within the generator channel, wherein a stream of pressurized air passes through the vacuum generator causing a reduction in air pressure in the generator channel that subsequently induces air in an interior of a fire hose section connected to the hose connector to flow into the vacuum aperture and be directed out the exhaust port.
US09033672B2 Wind turbines and wind turbine rotor blades with reduced radar cross sections
Wind turbine rotor blades with a reduced radar cross sections include a shell having a leading edge opposite a trailing edge, a structural support member that supports the shell and is disposed internal the wind turbine rotor blade between the leading edge and the trailing edge and extends for at least a portion of a rotor blade span length, wherein the structural support member comprises fiberglass, one or more cavities internal the wind turbine rotor blade, and a lightweight broadband radar absorbing filler material disposed in at least one of the one or more cavities to provide the reduced radar cross section.
US09033671B2 Wind turbines and wind turbine rotor blades with reduced radar cross sections
Wind turbine rotor blades include a shell having a leading edge opposite a trailing edge, a structural support member that supports the shell and is disposed internal the wind turbine rotor blade between the leading edge and the trailing edge and extends for at least a portion of a rotor blade span length, and a resistive cellular support structure disposed at least partially about the wind turbine rotor blade that physically supports at least a portion of the wind turbine rotor blade and at least partially absorbs radar energy.
US09033664B2 Blade for a turbine operating in water
A blade for use in water, the blade comprising an outer shell of fiber reinforced plastic defining a cavity. A substantial portion of the cavity is filled with a resin which adheres to the inner wall of the shell.
US09033660B2 Method for operating a wind turbine, arrangement and system
A method is provided for operating a wind turbine having an elongated stand apparatus, a generator rotatably mounted on the stand apparatus, and a rotor coupled to the generator via a rotor hub and the wind turbine also having an elongated rotor blade. A position of a radar system is determined with respect to the wind turbine and at least one area is determined for the rotational axis of the rotor as a function of the determined position which is not intended to be permanently assumed for alignment of the rotational axis of the rotor about the longitudinal axis of the stand apparatus. The wind turbine is operated with the at least one determined area not being permanently assumed for the alignment of the rotational axis of the rotor about the longitudinal axis of the stand apparatus.
US09033659B2 Method of manufacturing a wind turbine blade having predesigned segment
A blade for a rotor of a wind turbine is manufactured with a root region with a substantially circular or elliptical profile closest to the hub, an airfoil region with a lift generating profile furthest away from the hub and a transition region having a profile gradually changing the root region to the airfoil region. A first blade design is used for the first base part on a first longitudinal section of an airfoil region of a second blade, so that an induction factor of the first base part on the second blade deviates from a target induction factor. The first longitudinal section of the second blade is provided with flow altering devices so as to adjust the aerodynamic properties of the first longitudinal segment to substantially meet the target induction factor at the design point on the second blade.