Document Document Title
US09006781B2 Devices for monolithic data conversion interface protection and methods of forming the same
Apparatus and methods for monolithic data conversion interface protection are provided herein. In certain implementations, a protection device includes a first silicon controlled rectifier (SCR) and a first diode for providing protection between a signal node and a power high supply node, a second SCR and a second diode for providing protection between the signal node and a power low supply node, and a third SCR and a third diode for providing protection between the power high supply node and the power low supply node. The SCR and diode structures are integrated in a common circuit layout, such that certain wells and active regions are shared between structures. Configuring the protection device in this manner enables in-suit input/output interface protection using a single cell. The protection device is suitable for monolithic data conversion interface protection in sub 3V operation.
US09006775B1 Light-emitting diode
A light-emitting diode (LED), including a first semiconductor layer defining several light-emitting regions and non-light-emitting regions; an active layer and a second semiconductor layer sequentially formed over the first semiconductor layer in the light-emitting regions; a transparent conductive layer formed over the second semiconductor layer; a Bragg reflector structure formed over the transparent conductive layer and including several first via holes; a metal layer formed over the Bragg reflector structure and connected to the transparent conductive layer through the first via holes; a passivation layer covering the metal layer and including several second via holes; several third via holes exposing the first semiconductor layer in the non-light-emitting regions; several first electrodes filling the third via holes and connected to the first semiconductor layer; and several second electrodes filling the second via holes and connected to the metal layer.
US09006771B2 Organic light emitting diode and method for manufacturing the same
An exemplary embodiment of the present invention provides an organic light emitting diode, comprising a substrate, a first electrode, an organic material layer, and a second electrode, wherein a trench comprising a concave part and a convex part is provided on the substrate, the first electrode is provided on the substrate on which the trench is formed by being deposited, and an auxiliary electrode is provided on the first electrode. The organic light emitting diode according to the exemplary embodiment of the present invention may increase surface areas of the first electrode and the auxiliary electrode formed on the substrate, thereby implementing a low resistance electrode. In addition, since a line width of the electrode is not increased, it is possible to prevent a decrease of an opening ratio of the organic light emitting diode.
US09006770B2 Light emitting diode carrier
A light emitting diode (LED) carrier assembly includes an LED die mounted on a silicon submount, a middle layer that is thermally conductive and electrically isolating disposed below the silicon submount, and a printed circuit board (PCB) disposed below the middle layer. The middle layer is bonded with the silicon submount and the PCB.
US09006769B2 Organic electroluminescence element
Provided is a highly-reliable organic electroluminescence element in which loss of light due to surface plasmons generated on a metal surface is suppressed, the efficiency of light extraction to outside the element, and short circuits are unlikely to occur. The organic electroluminescence element includes a metal layer (1), on a surface of which a nanosize uneven structure is provided by a nanoparticle arrangement structure (6) in which nanoparticles (6a) are arranged in a planar fashion, and an organic layer (3) disposed on the uneven surface of the metal layer (1) and constituted by a plurality of layers including a light-emitting layer (31). Each interface between the plurality of layers of the organic layer (3) is flatter than the uneven surface of the metal layer (1).
US09006767B2 Luminophore composition for UV-visible light conversion and light converter obtained therefrom
A luminophore composition comprising amorphous aluminoborate powders is disclosed. The composition is obtainable by preparing an aluminoborate resin by a wet chemical route based on precursors solutions substantially free from monovalent and divalent cations; drying the resin to obtain a solid; grinding the solid to obtain a powder; pyrolyzing the powder at a pyrolysis temperature lower than the crystallization temperature of the composition; and calcinating the powder so pyrolyzed at a calcination temperature lower than the crystallization temperature of the composition. Furthermore, a process for the preparation of said composition is disclosed. The composition is particularly suitable for use in solid-state lighting, and for example for converting UV light into warm white visible light.
US09006763B2 Semiconductor light-emitting device and light source device using the same
A semiconductor light-emitting device according to the present invention is a semiconductor light-emitting device 10 including a solid-state light-emitting element 11 and a wavelength converter 12 that converts primary light emitted by the solid-state light-emitting element 11 into light having a longer wavelength, wherein the wavelength converter 12 includes a wavelength converting layer 12a made from a translucent inorganic formed body containing phosphors, and a binder layer 12b; the wavelength converter 12 is disposed on a main light extraction surface 11a of the solid-state light-emitting element 11; and the binder layer 12b is disposed along an emission direction of light emitted from the main light extraction surface 11a.
US09006761B2 Light-emitting device
A light-emitting device includes a substrate (4), a light-emitting element (10) mounted on the substrate (4), a first resin (12) disposed to cover an upper portion of the light-emitting element (10), a second resin (14) disposed to cover a lower portion of the light-emitting element (10), a first phosphor (18) contained in the first resin (12), and a second phosphor (20) contained in the second resin (14). The first phosphor (18) converts light emitted directly from the light-emitting element (10) into a first phosphor-converted light having a wavelength longer than that of the light emitted directly from the light-emitting element (10) and emits the first phosphor-converted light, and the second phosphor (20) converts the light emitted directly from the light-emitting element (10) into a second phosphor-converted light having a wavelength longer than that of the first phosphor-converted light and emits the second phosphor-converted light. Because both the first and second resins (12, 14) have portions in contact with the light-emitting element (10), respectively, the first and second phosphors (18, 20) receive the light emitted directly from the light-emitting element (10) to convert the light emitted from the light-emitting element (10) into the first and second phosphor-converted lights, respectively. Positions of the first and the second resins are arranged depending on the wavelength range of light which respective phosphors can convert.
US09006760B2 Display panel and display device
A display panel includes: a substrate on which a plurality of feed terminals corresponding to a plurality of pixels are provided; a plurality of pixel electrodes corresponding to the respective pixels; a common electrode common to the pixels; and a plurality of light-emitting layers corresponding to the respective pixels and provided between the pixel electrodes and the common electrode. In plan view, within each of the pixels, the light-emitting layer and the feed terminal do not overlap, feed terminals of each column of pixels are provided in a column, and the common electrode is electrically connected to conductive layers, the conductive layers each having a shape of a line that overlaps a corresponding one of the columns of feed terminals. Accordingly, the display panel achieves a high aperture ratio even with the conductive layers formed therein.
US09006759B2 Light-emitting device
A light-emitting device is provided that aims not to affect a service life and characteristics of light emission and includes two electrodes formed on the upper surface of a substrate with a gap at a central portion of the upper surface of the substrate between the two electrodes, a first light-emitting diode element mounted on the first electrode, and a second light-emitting diode element mounted on the second electrode. The first light-emitting diode element includes a pair of element electrodes on an upper surface of the first light-emitting diode element and the second light-emitting diode element includes a pair of element electrodes on an upper surface of the second light-emitting diode element. The first light-emitting diode element is connected by a wire to the first electrode and/or the second electrode. The second light-emitting diode element is connected by a wire to the first electrode and/or the second electrode.
US09006758B2 Light-emitting element and display device using same
A light-emitting element includes a reflective electrode, a light-transmitting electrode disposed opposite the reflective electrode, a light-emitting layer emitting blue light disposed between the reflective electrode and the light-transmitting electrode, and a functional layer disposed between the reflective electrode and the light-emitting layer. The optical thickness of the functional layer is no less than 428.9 nm and no more than 449.3 nm.
US09006754B2 Multichip light emitting diode (LED) and method of manufacture
The present invention provides a multichip LED and method of manufacture in which white light is produced. Specifically, a plurality of electrically interconnected LED chips (e.g., interconnected via red metal wire) is selected for conversion of light to white light. In a typical embodiment, the LED chips comprise: a blue LED chip, a red LED chip, a green LED chip, and a target LED chip whose light output is converted to white light. A wavelength of a light output by one or more of the plurality of chips will be measured. Based on the wavelength measurement, a conformal coating is applied to the one or more of the LED chips. The conformal coating has a phosphor ratio that is based on the wavelength. Moreover, the phosphor ratio is comprised of at least one of the following colors: yellow, green, or red. Using the conformal coating the light output of the target LED is then converted to white light. In a typical embodiment, these steps are performed at the wafer level so that uniformity and consistency in results can be better obtained. Several different approaches can be implemented for isolating the coating area. Examples include the use of a paraffin wax, a silk screen, or a photo resist. Regardless, this approach allows multiple chips to be treated simultaneously.
US09006751B2 Luminous vehicle glazing and manufacture thereof
A luminous vehicle glazing containing: a first sheet having a first and a second main face; a peripheral light source, the emitting face facing an injection side, which is a side of the second face; a surface diffusion extractor, which extracts the guided light via the first and/or the second main face, or a volume diffusion extractor in the first sheet; a fluid-tight cap, which covers the peripheral light source and is impermeable to liquid water or water vapor, wherein the cap is a facial cap, faces the second face, joined by a fastening element, and associated with an interfacial sealing element.
US09006750B2 Optical semiconductor package, optical semiconductor module, and manufacturing method of these
An optical semiconductor package has a base material that includes a principal surface, an optical semiconductor element that is located on the principal surface of the base material to project or receive light, and an optical transparency sealing layer that seals the optical semiconductor element while covering the principal surface of the base material. An air gap having a shape surrounding an optical axis of the optical semiconductor element is provided in the optical transparency sealing layer such that the light is reflected by an interface of a portion corresponding to an inner circumferential surface of the air gap in an interface formed by the air gap and the optical transparency sealing layer.
US09006749B2 Quantum dot laser diode and method of manufacturing the same
Provided are a quantum dot laser diode and a method of manufacturing the same. The method of manufacturing a quantum dot laser diode includes the steps of: forming a grating structure layer including a plurality of gratings on a substrate; forming a first lattice-matched layer on the grating structure layer; forming at least one quantum dot layer having at least one quantum dot on the first lattice-matched layer; forming a second lattice-matched layer on the quantum dot layer; forming a cladding layer on the second lattice-matched layer; and forming an ohmic contact layer on the cladding layer. Consequently, it is possible to obtain high gain at a desired wavelength without affecting the uniformity of quantum dots, so that the characteristics of a laser diode can be improved.
US09006746B2 Schottky barrier diode and method for manufacturing schottky barrier diode
A Schottky barrier diode and a method of manufacturing the diode are provided. The diode includes an n− type epitaxial layer disposed on a first surface of an n+ type silicon carbide substrate and a plurality of p+ regions disposed within the n− type epitaxial layer. An n+ type epitaxial layer is disposed on the n− type epitaxial layer, a Schottky electrode is disposed on the n+ type epitaxial layer, and an ohmic electrode is disposed on a second surface of the n+ type silicon carbide substrate. The n+ type epitaxial layer includes a plurality of pillar parts disposed on the n− type epitaxial layer and a plurality of openings disposed between the pillar parts and that expose the p+ regions. Each of the pillar parts includes substantially straight parts that contact the n− type epitaxial layer and substantially curved parts that extend from the substantially straight parts.
US09006743B2 Thin film transistor, thin film transistor array substrate, and method for making the same
The present invention provides a thin film transistor including a first drain electrode, a second drain electrode, a first source electrode, and a second source electrode, wherein the first drain electrode and the first source electrode jointly define a first U-shaped channel facing toward a first direction. Wherein the second drain electrode and the second source electrode jointly define a second U-shaped channel facing a second direction which is different to the first direction, wherein the bottom width of the second U-shaped channel is larger then the bottom width of the first U-shaped channel. The present invention further provides an array substrate of the thin film transistor, and a method for making the array substrate. By way of the forgoing, short-circuit between the source electrode and the drain electrode resulted from the cleaning agent residue located in the bottom of the U-shaped channel of the thin film transistor can be avoided.
US09006742B2 Thin film transistor array panel
A manufacturing method of a thin film transistor array panel includes: simultaneously forming a gate conductor and a first electrode on a substrate, using a non-peroxide-based etchant; forming a gate insulating layer on the gate conductor and the first electrode; forming a semiconductor, a source electrode, and a drain electrode on the gate insulating layer; forming a passivation layer on the semiconductor, the source electrode, and the drain electrode; and forming a second electrode layer on the passivation layer.
US09006736B2 Semiconductor device
To give favorable electrical characteristics to a semiconductor device. The semiconductor device includes an insulating layer, a semiconductor layer over the insulating layer, a pair of electrodes over the semiconductor layer and each electrically connected to the semiconductor layer, a gate electrode over the semiconductor layer, and a gate insulating layer between the semiconductor layer and the gate electrode. The insulating layer includes an island-shaped projecting portion. A top surface of the projecting portion of the insulating layer is in contact with a bottom surface of the semiconductor layer, and is positioned on an inner side of the semiconductor layer when seen from above. The pair of electrodes covers part of a top surface and part of side surfaces of the semiconductor layer. Furthermore, the gate electrode and the gate insulating layer cover side surfaces of the projecting portion of the insulating layer.
US09006733B2 Semiconductor device and method for manufacturing thereof
In a semiconductor device including a transistor using an oxide semiconductor film, stable electric characteristics can be provided and high reliability can be achieved. A structure of the semiconductor device, which achieves high-speed response and high-speed operation, is provided. In a semiconductor device including a transistor in which an oxide semiconductor film, a gate insulating film, and a gate electrode layer are stacked in order and a sidewall insulating layer is provided on the side surface of the gate electrode layer, the sidewall insulating layer has an oxygen-excess regions, which is formed in such a manner that a first insulating film is formed and then is subjected to oxygen doping treatment, a second insulating is formed over the first insulating film, and a stacked layer of the first insulating film and the second insulating film are etched.
US09006730B2 Metal oxide semiconductor structure and production method thereof
A metal oxide semiconductor structure and a production method thereof, the structure including: a substrate; a gate electrode, deposited on the substrate; a gate insulation layer, deposited over the gate electrode and the substrate; an IGZO layer, deposited on the gate insulation layer and functioning as a channel; a source electrode, deposited on the gate insulation layer and being at one side of the IGZO layer; a drain electrode, deposited on the gate insulation layer and being at another side of the IGZO layer; a first passivation layer, deposited over the source electrode, the IGZO layer, and the drain electrode; a second passivation layer, deposited over the first passivation layer; and an opaque resin layer, deposited over the source electrode, the second passivation layer, and the drain electrode.
US09006729B2 Semiconductor device and manufacturing method thereof
It is an object to provide a method for manufacturing a highly reliable semiconductor device having a thin film transistor formed using an oxide semiconductor and having stable electric characteristics. The semiconductor device includes an oxide semiconductor film overlapping with a gate electrode with a gate insulating film interposed therebetween; and a source electrode and a drain electrode which are in contact with the oxide semiconductor film. The source electrode and the drain electrode include a mixture, metal compound, or alloy containing one or more of a metal with a low electronegativity such as titanium, magnesium, yttrium, aluminum, tungsten, and molybdenum. The concentration of hydrogen in the source electrode and the drain electrode is 1.2 times, preferably 5 times or more as high as that of hydrogen in the oxide semiconductor film.
US09006724B2 Organic light emitting diode display
An organic light emitting diode (OLED) display includes a pixel part on a substrate, the pixel part being configured to display an image, a peripheral part at a peripheral area of the pixel part, the peripheral part including a chip on film connection part, and a chip on film connected to the chip on film connection part, the chip on film connection part including a chip on film bonding part, the chip on film being attached to the chip on film bonding part, and an array test part separated from the chip on film bonding part, the array test part being contacted with a probe pin.
US09006723B2 Organic light-emitting diode (OLED) display
An organic light-emitting diode (OLED) display is disclosed. In one aspect, the OLED display includes a substrate, an organic light-emitting portion, a sealing member, and first and second connecting members. The organic light-emitting portion includes a first electrode positioned on the substrate, an organic light-emitting layer formed on the first electrode, and a second electrode formed on the organic light-emitting layer. The sealing member includes a first conductive layer positioned on the organic light-emitting portion and electrically connected to the second electrode, a second conductive layer electrically connected to the first electrode, and an insulating layer interposed between the first and second conductive layers. The first connecting member is connected to the first conductive layer to supply a first power source, and the second connecting member is connected to the second conductive layer to supply a second power source.
US09006722B2 Light emitting display
A light emitting device includes a pixel defining layer including a plurality of pixel defining layer elements, on a substrate; a first electrode in a space defined by the substrate and the pixel defining layer; a light emitting layer in a space defined by the first electrode and the pixel defining layer; and a second electrode on the light emitting layer and the pixel defining layer. The second electrode includes a plurality of layers, and an insulating layer between the plurality of layers, overlapping the light emitting layer, and exposing a layer among the plurality of layers in an area corresponding to the pixel defining layer.
US09006721B2 Organic light-emitting diode
An organic light-emitting diode includes a substrate, a first electrode on the substrate, a second electrode facing the first electrode, an emission layer interposed between the first electrode and the second electrode, a hole transportation region between the first electrode and the emission layer, and an electron transportation region interposed between the emission layer and the second electrode. The hole transportation region includes a first compound represented by Formula 1 below, and at least one of the hole transportation region and the emission layer includes a second compound represented by Formula 100 below: wherein Ar101, Ar102, xa, xb, R101-R119, Ar50, Ar60, R51-R60 and p are further defined.
US09006719B2 OLED pixel structure and OLED panel each having three colored light emitting zones arranged in parallel
The present disclosure provides an organic light emitting diode (OLED) pixel structure and an OLED panel. The pixel structure comprises a plurality of colored light emitting zones arranged in parallel. The colored light emitting zone of each color is divided into a second zone, a first zone, and a third zone. A distance is set between the second zone and the first zone, and a distance is set between the second zone and the third zone. Anodes of the first zone, the second zone, and the third zone are connected with a first reference voltage by a thin film transistor (TFT), a cathode of the second zone is connected to a second reference voltage, a cathode of the first zone is connected to a first interface, and a cathode of the third zone is connected to a second interface.
US09006718B2 Organic electroluminescence display panel and manufacturing method
A organic EL display panel and similar are provided so as to constrain a gradual increase in contact resistance between a common electrode and a power supply layer. In a panel including a substrate, a pixel electrode, a power supply layer formed with separation from the pixel electrode, a resin partition layer having an aperture over the power supply layer and over the pixel electrode, an organic light-emitting layer, a functional layer in contact with the organic light-emitting layer in the aperture and electrically connected to the power supply layer, and a common electrode, an inorganic film is disposed between the functional layer and side walls of an opening for the aperture over the power supply layer in the resin partition layer.
US09006717B2 Organic light-emitting display apparatus and method of manufacturing organic light-emitting display apparatus
An organic light-emitting display apparatus includes a substrate, a plurality of organic light-emitting diodes on the substrate, and a plurality of capacitors located next to at least one side of one of the organic light-emitting diodes. The capacitors are arranged inside trenches within the substrate.
US09006716B2 Dopant for a hole conductor layer for organic semiconductor components, and use thereof
The invention relates to novel metal-organic materials for hole injection layers in organic electronic components. For example, in light-emitting components such as organic light diodes (OLED) or organic light-emitting electrochemical cells (OLEEC) or organic field effect transistors or organic solar cells or organic photo detectors. Luminescence (cd/m2), efficiency (cd/A), and service life (h) of organic electronic components such as from organic light diodes in particular are highly dependent on the exciton thickness in the light-emitting layer and on the quality of the charge carrier injection and are also limited by same, among other things. The invention relates to a hole injection layer consisting of quadratic planar mononuclear transition metal complexes such as copper 2+ complexes, for example, which are embedded into a hole-conducting matrix.
US09006715B2 Electronic device
A method of making an electronic device comprising a double bank well-defining structure, which method comprises: providing an electronic substrate; depositing a first insulating material on the substrate to form a first insulating layer; depositing a second insulating material on the first insulating layer to form a second insulating layer; removing a portion of the second insulating layer to expose a portion of the first insulating layer and form a second well-defining bank; depositing a resist on the second insulating layer and on a portion of the exposed first insulating layer; removing the portion of the first insulating layer not covered by the resist, to expose a portion of the electronic substrate and form a first well-defining bank within the second well-defining bank; and removing the resist. The method can provide devices with reduced leakage currents.
US09006705B2 Device with strained layer for quantum well confinement and method for manufacturing thereof
The disclosed technology relates to transistors having a strained quantum well for carrier confinement, and a method for manufacturing thereof. In one aspect, a FinFET or a planar FET device comprises a semiconductor substrate, a strain-relaxed buffer layer comprising Ge formed on the semiconductor substrate, a channel layer formed on the strain-relaxed buffer layer, and a strained quantum barrier layer comprising SiGe interposed between and in contact with the strain-relaxed buffer layer and the channel layer. The compositions of the strain-relaxed buffer layer, the strained quantum barrier layer and the channel layer are chosen such that a band offset of the channel layer and a band offset of the strained quantum barrier layer have opposite signs with respect to the strain-relaxed buffer layer.
US09006693B2 Energy degrader and charged particle irradiation system including the same
An energy degrader includes: a damping unit that attenuates energy of incident charged particles and has a thickness changing stepwise or continuously according to a position of a two-dimensional coordinate system within a plane crossing a traveling direction of charged particles; and a driving unit that performs translational driving of the damping unit in first and second axial directions that are directions of two axes crossing each other in the two-dimensional coordinate system.
US09006687B2 Optical unit, fluorescence detection device, and fluorescence detection method
A first lens configured to convert light from the objective lens into parallel light includes a concave lens part having a concave curved face in a center portion of a flat face, and a convex lens part having a convex curved face around a flat face. Further, the first lens includes first and second regions configured to diverge light through the flat face and the concave curved face and a third region configured to collect light through the convex curved face and the concave curved face. When the sample is on a sample table and sealed in a two-dimensional electrophoresis substrate, light totally reflected by a side surface of the objective lens enters the second region. In contrast, when the sample is directly on the sample table, the light enters the third region.
US09006683B2 Portable sterilizing device
A portable sterilizing device for sterilizing at least one of a feeding bottle, a nipple, a bottle stopper, and a cap comprises: a sterilization covering body and a containing bottle. The sterilization covering body includes a covering member and a sterilizing member provided on the covering member, a UV-light emitting unit of the sterilizing member is emitting the UV light in a covering direction. The containing bottle includes a body portion and a connecting portion extensively formed from the body portion, the body portion covering the covering member along the covering direction in a manner that the connecting portion is attached to the attaching portion so as to form a containing space that faces toward the UV light for the sterilization. Thus, the portable sterilizing device has the advantages of small size and low power consumption, and therefore it is convenient for baby caretaker to portably carry it.
US09006676B2 Apparatus for monitoring ion implantation
An apparatus for monitoring an ion distribution of a wafer comprises a first sensor and a sensor. The first sensor, the second sensor and the wafer are placed in an effective range of a uniform ion implantation current profile. A controller determines the ion dose of each region of the wafer based upon the detected signal from the first sensor and the second sensor. In addition, the controller adjusts the scanning frequency of an ion beam or the movement speed of the wafer to achieve a uniform ion distribution on the wafer.
US09006672B2 Neutron detection
A neutron detector includes a microchannel plate having a structure that defines a plurality of microchannels, and layers of materials disposed on walls of the microchannels. The layers include a layer of neutron sensitive material, a layer of semiconducting material, and a layer of electron emissive material. For example, the layer of neutron sensitive material can include boron-10, lithium-6, or gadolinium.
US09006670B2 X-ray detector
An X-ray detector includes a top receiving container in which one or more subjects are disposed, an X-ray detection unit that detects shadow images of the one or more subjects when X-rays are radiated to the one or more subjects and calculates an X-ray radiation angle of the radiated X-rays based on the shadow images of the one or more subjects, and a bottom receiving container having a receiving space in which the X-ray detection unit is received.
US09006669B2 Radiation detector
According to one embodiment, a radiation detector includes a photodetector including a fluorescent film configured to convert radiation into light, and a photoelectric conversion element configured to convert light into an electrical signal, a circuit board configured to electrically drives the photodetector, and electronically processes an output signal from the photodetector, and a connection board configured to electrically connect the photodetector and circuit board, and including a flexible circuit board, and an IC mounting board connected to the flexible circuit board, less flexible than the flexible circuit board, and including an IC semiconductor element.
US09006666B2 Positron tomography imaging apparatus and method for multiphase flow
The present invention relates to a positron tomography imaging apparatus for a multiphase flow in an oil pipeline, which apparatus utilizes positron and electron annihilation generating a pair of coincidence gamma-rays of 511 keV energy as tomography imaging means and provides an on-line tomography imaging function for metering a multiphase flow in an oil pipeline of an oil field. The apparatus comprises a plurality of sets of parallel high-precision gamma-ray detector arrays with a particular space structure arrangement, a positron radioactive source and a shield, and can acquire a phase fraction of such multiphase flow mixture as oil, gas and water under a condition of a single radioactive source by combining an image processing function. The design of a plurality of sets of high-precision detector arrays also greatly improves accuracy of a multiphase flow metering and its applicability in multiphase flows of different flow patterns. The video information of fluid generated by it will significantly enrich oil, gas metering information for petroleum industry and provide basic data for a more effective reservoir management and production optimization.
US09006663B2 Radiation dosimeter detection system and method
A method for real-time RL and/or ROSL dose rate measuring in an environment exposed to a radiation source(s). The method comprises the steps of exposing a dosimeter to the environment for irradiation by the radiation source(s), the dosimeter comprising a phosphor-doped fluoroperovskite compound, sensing the RL or ROSL emitted light from the dosimeter during irradiation by the radiation source(s) and generating a representative light detection signal, and recording or generating a real-time measure of dose rate in the environment based on the light detection signal. A radiation dosimeter detection system comprising a phosphor-doped fluoroperovskite compound, the dosimeter coupled to a detector by an optical fiber. The detector comprises first and second optical stimulation sources that transmit light over the optical fiber to the dosimeter in first and second wavelength ranges. An optical detector senses light emitted from the dosimeter from which read-out dose information is generated.
US09006652B2 Phase shift method for a TEM
A method of electron microcopy passes an electron beam through a phase plate, specifically a Zernike type phase plate, comprising a central hole, and a thin film causing a phase shift of the electrons passing through said film. This phase shift causes the Contrast Transfer Function (CTF) to change from a sine-like function to a cosine-like function. The phase plate is equipped with a film in the form of an annulus, carried by a much thinner film. As a result only in a small spatial frequency range (for low frequencies) the phase is changed (and thus the CTF), and for other spatial frequencies the phase shift is negligible, and thus the CTF remains unchanged. Due to the much smaller thickness of the carrier film the scattering of electrons is negligible as well.
US09006650B2 Direct measurements of nanoparticles and virus by virus mass spectrometry
Apparatus and methods for performing mass spectrometry of a nanoparticle or virus analyte. Apparatus may include a laser desorption plate, a mass analyzer configured to measure mass over the range of m/z from 105 to 1010, an electrical shield surrounding the mass analyzer, and a charge sensitive detector, wherein the laser firing is phase lock synchronized with the applied radiofrequency voltages.
US09006647B2 Mass spectrometer
A collision or fragmentation cell is disclosed comprising a plurality of electrodes wherein a first RF voltage is applied to an upstream group of electrodes and a second different RF voltage is applied to a downstream group of electrodes. The radial confinement of parent ions entering the collision or fragmentation cell is optimized by the first RF voltage applied to the upstream group of electrodes and the radial confinement of daughter or fragment ions produced within the collision or fragmentation cell is optimized by the second different RF voltage applied to the downstream group of electrodes.
US09006646B2 Mass spectrometry apparatus
There is provided a mass spectrometry apparatus comprising: an ion source arranged in a substantially horizontal orientation and from which a quantity of ions may be sourced, an ion filter device arranged for receiving a stream of ions for filtering thereof; and, an ion guide arranged so as to guide ions sourced from the ion source toward the ion filter device. The ion source and the ion filter device are arranged relative to one another so that the profile of the apparatus is reduced so as to minimize the effective footprint of the apparatus.
US09006642B2 Focus adjustable apparatus
An embodiment of the invention provides a focus adjustable apparatus adapted to be disposed on a transparent substrate to modulate a plurality of rays passing through the transparent substrate. The focus adjustable apparatus includes a light modulation device, an eye tracking device, an eyesight status device and a controller. The light modulation device receives the rays from the transparent substrate and adjusts an emergent angle of each ray. The eye tracking device tracks a position of a user and estimates a distance between the user and the focus adjustable apparatus. The eyesight status device obtains an eyesight data of the user. The controller provides a control signal to drive the light modulation device by estimating the emergent angle of the each ray according to the distance between the user and the focus adjustable apparatus and the eyesight data of the user.
US09006639B2 Pixel architecture with the control terminal of a first switch coupled to the control terminal of a second switch and method
In accordance with an embodiment, a pixel includes at least two switches, each switch having a control terminal and first and second current carrying terminals. The control terminals of the first and second switches are commonly connected together. In accordance with another embodiment, a method for transferring charge from a first switch to a capacitance includes applying voltage to the commonly connected control terminals of the first and second switches.
US09006638B2 Dual-mode capacitive transimpedance amplifier, and read-out device incorporating the same
A capacitive transimpedance amplifier for a detector unit capable of generating first and second detection currents comprises: a read-out circuit including an integration capacitor coupled between an input node connected to the detector unit, and a common node between first and second transistors connected in series, and a sampling and holding unit coupled between the first common node and an output node for sampling and holding a voltage at the first common node; and a switch unit connected to control ends of the first and second transistors and the input node, and operable between a first state, where the first detection current is read out, and a second state, where the second detection current is read out.
US09006631B2 Image sensor and row averaging method for image sensor
An image sensor and a row averaging method for an image sensor capable of simultaneously selecting the pixels of the same color in the same column of different rows in a pixel array and performing a signal process, thereby preventing an increase in an area and a decrease in the sensing speed of the pixels in the sub-sampling mode and the binning mode of the image sensor.
US09006630B2 Quality of optically black reference pixels in CMOS iSoCs
Aspects relate to improved optically black reference pixels in a CMOS iSoc sensor. A system can include a pointer P1 that indicates pixels to be read out during a readout time interval, a pointer P2 that indicates pixels to be reset during the time interval, and a pointer P3 that preserves a validity of a frame. The system also includes a pointer P4 configured to mitigate an integration time of column fixed pattern noise (FPN) rows independently of the integration time of other rows. In some aspects, pointer P4 can mitigate blooming into sampled rows from surrounding rows. Pointer P4 can be continuously rotated, in an aspect. Further, in some aspects, pointer P4 can jump on a second cycle to arrive one line before pointer P1.
US09006629B2 Controlling laser power
An intensity of radiation emitted from at least two laser diodes of a projecting apparatus is optimized by providing an offset distance between at least two focal points of the at least two laser diodes and providing a maximum value for radiation intensity emitted by each of the laser diodes, irrespective of simultaneous transmission by one of the laser diodes with another of the laser diodes. The intensity of the radiation emitted from each of the at least two laser diodes is adjusted such that an aggregated value of the radiation intensity emitted by all of the laser diodes within a predefined period of time may exceed a threshold value allowed for the maximum permissible exposure to radiation.
US09006628B2 Small smart weapon and weapon system employing the same
A weapon and weapon system, and methods of manufacturing and operating the same. In one embodiment, the weapon includes a warhead having destructive elements. The weapon also includes a folding lug switch assembly that provides a mechanism to attach the weapon to a delivery vehicle and is configured to close after launching from the delivery vehicle, thereby satisfying a criterion to arm the warhead. The weapon still further includes a guidance section including an antenna configured to receive mission data before launching from the delivery vehicle and further configured to receive instructions after launching from the delivery vehicle to guide the weapon to a target.
US09006627B2 Lighting system for use with a microwave oven
A microwave oven includes a top wall, side walls, and a bottom wall at least partially defining a cavity of the microwave oven, and a table coupled to the bottom wall. The table has a top surface and an opposing bottom surface. The top surface is configured to support an item within the cavity. A light source directs light to the table. The table is configured to diffuse light emitted from the light source into the cavity.
US09006618B2 Combined seat heater and capacitive occupancy sensor
A combined seat heater and capacitive occupancy sensor comprises a heating element (10) connected between a first (21) and a second (22) node, and a capacitive sensing network connected to the heating element to apply an oscillating voltage thereto and to derive the capacitive load of the heating element. A common mode choke (16) connects the first and second node to a third (23) and fourth (24) node, respectively. The capacitive sensing network comprises an oscillator (28), AC-coupled to the third and/or the fourth node to drive oscillating voltage into that node, and a transimpedance amplifier (32), which has a first input to receive the oscillating voltage as reference voltage and a second input operatively connected to the heating element. The transimpedance amplifier maintains a voltage on its second input equal to the reference voltage by driving a current into the second input. An output signal (44) indicates the AC component of the current driven into the second input.
US09006616B2 Portable spa monitoring and control circuitry
Control circuitry for controlling a spa water heater, wherein a microcontroller is configured to detect zero crossings of an A.C. line voltage from a voltage sense signal, to cause closing of a first heater relay and a second heater relay, to detect the time at which heater current is initially sensed by a current sensor after the initial closing of the second heater relay, to measure a time delay between the time that the second heater relay is closed and the time at which heater current is initially sensed, and to adjust the time at which a second closing of the second heater relay occurs such that zero crossings of the heater current occur at the same time as zero crossings of the voltage waveform. The control circuitry further includes a voltage sense circuit comprising a first diode connected in series with a current limiting resistance connected in series with a Zener diode, which is in turn connected in series with an optical coupler LED.
US09006615B2 Temperature auto-compensation grill
A temperature auto-compensation grill includes rotatingly connected upper and lower grilling units; a heating circuit including a heater and a thermostat having a change-over switch; and an operating mechanism including a linkage that is slidingly connected to the lower grilling unit, a first end of the linkage making contact with the change-over switch and a second end of the linkage extending from the lower grilling unit and making contact with the withstand portion of the upper grilling unit in an open position. The upper grilling unit has a withstand portion withstands that contacts the second end of the linkage and slidingly pushes the linkage when the upper grilling unit rotates from a closed position to an open position. The thermostat has a first steady temperature in the closed position, and a second steady temperature in the open position, and the first steady temperature is lower than the second steady temperature.
US09006606B2 Flexible drill and method of joining nitinol to dissimilar metals
A flexible drill with a shaft having a nitinol portion (or nitinol region) provided between a stainless steel driver end and a stainless steel drill tip. The flexible drill with nitinol shaft is provided with a bearing surface to allow centering within a drill guide, low friction bearing and flexibility to drill around a curve. The bearing surface may be formed of a fluoropolymer such as LDPE (Low Density Polyethylene). The flexible drill shaft may be used through a drill guide, such as a curved drill sleeve.
US09006602B2 Gas insulated switchgear
A gas insulated switchgear includes an enclosure, a first fixed conductor, one side of the first fixed conductor being bent at a right angle and another side of the first fixed conductor being fixed on one side of the enclosure, a second fixed conductor configured to be spaced apart from the first fixed conductor and configured to be fixed on another side of the enclosure, a screw configured to form an axis on inner of the enclosure and being spaced apart from the first and second fixed conductors and a movable conductor configured to move along the axis through a rotation of the screw, one side of the movable conductor being in contact with the second fixed conductor.
US09006601B2 Arc chamber for bi-directional DC
A circuit breaker including a pair of separable contacts and an arc chamber is provided. The separable contacts include a fixed contact having an upper surface. The arc chamber includes magnetic members disposed on either side of the separable contacts. The magnetic members have a lower surface below the fixed contact upper surface.
US09006599B2 Method and device for sorting products
The invention concerns a method and apparatus for sorting a stream of products by scanning this stream of products with a bundle of concentrated light and analyzing the light originating from the scanned products and a background element, wherein this background element is chosen such that the corresponding detected light signal differs from the light signals originating from the products to be sorted in at least one parameter and wherein one or more control signals are generated by shifting the background level of the observed light signals to a signal level chosen such that, in the thus obtained signal, the signal level of the signal of a scanned product to be accepted distinguishes itself from the signal level of the signal of a scanned product to be rejected.
US09006592B2 Entertainment button device and game machine
An entertainment button device includes: an entertainment button that a player can push; and a button-up-and-down mechanism configured to move the entertainment button up and down from a predetermined normal operation position to a protruding position in which the entertainment button protrudes upward from the normal operation position. The button-up-and-down mechanism includes: a bias member configured to bias the entertainment button in a moving-up direction; a shaft member extending in a moving direction of the entertainment button; a rotating mechanism configured to rotate the shaft member; an engagement part configured to move up and down together with the entertainment button; and a spiral guide part formed on an outer periphery of the shaft member in a spiral manner, wherein the engagement part engages with the spiral guide part.
US09006581B2 Printed wiring board and method of manufacture thereof
A printed wiring board, including a printed wiring member which respectively has object conductor that is subjected to electromagnetic wave shielding on at least one surface of an insulating layer; and an electromagnetic wave shielding member which has an electromagnetic wave shielding layer composed of a low-resistance section and a high-resistance section on at least one surface of a base film. The printed wiring member and the electromagnetic wave shielding member are bonded together with interposition of insulating adhesive layers, and with arrangement of the electromagnetic wave shielding layer separately and in opposition so that the object conductor is covered. The electromagnetic wave shielding layer and the object conductor are composed of the same type of conductive material, and the electromagnetic wave shielding layer is not exposed at the circumferential end faces of the printed wiring board.
US09006580B2 Method of manufacturing multilayer wiring substrate, and multilayer wiring substrate
Disclosed is a method of manufacturing a multilayer wiring substrate having a principal plane of the substrate and a rear plane thereof, having a structure such that a plurality of resin insulating layers and a plurality of conductor layers are laminated, and a plurality of chip component connecting terminals to which chip components are connectable are disposed on the principal plane of the substrate. This method has a feature including a plating layer forming process in which product plating layers which provide the plurality of chip component connecting terminals and a dummy plating layer on the surrounding of the product plating layers are formed on the surface of an exposed outermost resin insulating layer at the principal plane of the substrate. This method permits a thickness dispersion of the chip component connecting terminals to be suppressed and permits a connection reliability thereof to the chip components to be increased.
US09006574B2 Undersea cable, multilayer tape for water shielding layer of undersea cable, and method for improving fatigue characteristics of undersea cable
A power line core in an undersea cable includes a conducting member, an insulating member, a shield layer, a water shielding layer, an anticorrosion layer and the like. The insulating member is provided on an outer periphery portion of the conducting member. The insulating member is made of, for example, crosslinked polyethylene. The shield layer is provided on an outer periphery of the insulating member. The water shielding layer is provided on an outer periphery portion of the shield layer. The water shielding layer includes a multilayer tape in which a metal layer is sandwiched by resin layers. The anticorrosion layer is provided on an outer periphery portion of the water shielding layer. In the cross section of the multilayer tape, the metal layer has a corrugated shape.
US09006573B2 Motor vehicle lock composed of mechanical and electrical, electromotive and/or electronic components
A motor vehicle lock containing mechanical locking elements and/or latching elements as well as electrical, electromotive, and/or electronic components that interact with the mechanical locking elements and/or latching elements, wherein the electrical, electromotive, and/or electronic components are attached to a part of a housing (10), wherein an electric line attached to the part of the housing (10) is connected to at least one of the electrical, electromotive, and/or electronic components, wherein the electric line comprises a single-strand or multi-strand, flexible cable, wherein a cable path (19a, 19b) of the cable (8) passes through a cable conduit (15) disposed in the part of the housing (10), wherein the cable conduit (15) comprises a permanently, plastically-deformed material, at least at one side of the cable path (19a, 19b), whereby a deformation (V) in the material immobilizes the cable (8) in the cable conduit (15).
US09006571B2 Bus system connecting bus bars and a method of connecting bus bars
According to an aspect of the disclosure, there is provided an electrical distribution bus system that includes first and second bus bars, a dielectric insulator, and at least one fastener coupling the bus bars and dielectric insulator. Each of the bus bars includes an elbow portion from which a pair of straight portions extends at elbow angles, the straight portions being disposed at right angles to each other. The dielectric insulator has a length and a width, the width being no greater than twice the length, the length extending perpendicularly between the elbow portions. The fastener couples the dielectric insulator between the bus bars, the dielectric insulator electrically insulating the first and second bus bar from one another.
US09006569B2 Electrically isolated heat dissipating junction box
A junction box used for making electrical connections to a photovoltaic panel. The junction box has two chambers including a first chamber and a second chamber and a wall common to and separating both chambers. The wall may be adapted to have an electrical connection therethrough. The two lids are adapted to seal respectively the two chambers. The two lids are on opposite sides of the junction box relative to the photovoltaic panel. The two lids may be attachable using different sealing processes to a different level of hermeticity. The first chamber may be adapted to receive a circuit board. The junction box may include supports for mounting a printed circuit board in the first chamber. The second chamber is configured for electrical connection to the photovoltaic panel. A metal heat sink may be bonded inside the first chamber. The first chamber is adapted to receive a circuit board for electrical power conversion, and the metal heat sink is adapted to dissipate heat generated by the circuit board.
US09006568B2 Synthesis of photovoltaic conjugated polymers
A method of making a fluorothieno[3,4-b]thiophene derivatives and photovoltaic polymers containing same using 3-bromothiophene-2-carboxylic acid as a starting material. This synthetic route provides an easier synthesis as well as greater yield and a purer product, which produces superior results over the prior art less pure products. The resulting materials can be used in a variety of photovoltaic applications and devices, especially solar cells.
US09006565B2 Opaque fluoropolymer composition comprising white pigments for photovoltaic elements of solar cells
A fluoropolymer composition having a total luminous transmittance (TT) of less than 15%, when measured according to ASTM D1003 on a sample having a thickness of about 50 μm, said composition comprising: at least one hydrogen-containing fluoropolymer [polymer (A)]; from 5 to 80% by weight of (A) of at least one inorganic pigment [pigment (I)]; and from 1 to 99% by weight of (I) of at least one per(halo)fluoropolymer chosen among tetrafluoroethylene (TFE) copolymers having a dynamic viscosity at a shear rate of 1 rad×sec−1 of less than 100 Pa×sec at a temperature of 280° C. [polymer (B)]. By adding polymer (B) to the composition based on polymer (A) it is advantageously possible to obtain an even dispersion of the pigment (I) so that a composition possessing outstanding opacity and still being processable under the form of films, so as to provide adequate mechanical properties, can be manufactured therefrom.
US09006564B2 Method of manufacturing solar cell and solar cell
A method for manufacturing a solar cell (100) includes the steps of removing a resist film (50) and removing a part of an n-type amorphous semiconductor layer (12n).
US09006562B2 High-concentration solar cell chip
A high-concentration solar cell includes an epitaxial layer structure, an upper patterned electrode on the top surface, and a back electrode on the back surface. The upper patterned electrode includes a primary pattern and a secondary pattern, where the primary pattern is composed of a series of small metal isosceles trapezoids around the perimeter of the cell. The narrower base of each metal trapezoid points toward an interior of the cell. A lead soldering pad is located within each metal trapezoid for being soldered to an external conductor for carrying the solar cell current. The secondary pattern consists of thin spaced conductors that connect to the angled sides and base of each trapezoid and spread current across the top surface of the cell. The current along the angled sides of each trapezoid is well-distributed to all the spaced conductors connected to the angled sides to avoid current crowding.
US09006560B2 Solar receiver
A lightweight reflector with a load bearing structure based on a tensile spoke-wheel. The spoke structure is especially compatible with dish parabolic mirrors, but has utility as a carrier structure for any round functional surface, including flat or slightly-curved mirrors used in central tower solar systems, parabolic dishes for radio telescopes and antennas, and for non-concentrating thin film solar panels. There are no radial members loaded in compression. All the spokes pull the rim inwards, and the rim is compressed in the circumferential direction. The imbalance in spoke tension results from the application of load provides the rigidity of the rim in respect to the hub, both for in-plane and out-of-plane forces. Ribs stiffen the spokes to resist wind and gravity, but are not structurally supported by either the hub or the rim. Lightweight reflector tiles match the wheel structure and create the reflective surface.
US09006557B2 Systems and methods for reducing current and increasing voltage in thermoelectric systems
A thermoelectric assembly and method are provided. The thermoelectric assembly can extend at least partially around a perimeter of a first fluid conduit. The thermoelectric assembly can include a plurality of thermoelectric sub-assemblies aligned with one another along the perimeter of the first fluid conduit. Each thermoelectric sub-assembly can include a plurality of thermoelectric elements in parallel electrical communication with one another, and at least one shunt a plurality of electrically insulating elements to prevent current flow in a plane perpendicular to the first direction between adjacent thermoelectric sub-assemblies.
US09006554B2 Human interface device with optical tube assembly
A human interface device may include at least one analog control pressure surface that may operate in conjunction with at least one optical tube assembly (OTA) to allow precision human control of signal modulation, such as an audio signal being generated by a musical instrument. Each OTA may be incorporated within a body and may include a tube and an emitter-sensor pair wherein when pressure is applied to at least one of the pressure surfaces, the amount of light transferred within a sensor-emitter pair of an OTA is altered to selectively effect the signal modulation. Any type of control range may be expressed that depends on dynamic range and “touch” control. Accordingly, the human interface device may allow more “feeling” or expressiveness through application of pressure rather than positioning.
US09006553B2 Rod-shaped electronic percussion instrument
A rod-shaped electronic percussion instrument is provided. A rod-shaped percussion instrument, which has a striking surface made of an elastic material in a substantially rectangular shape when viewed from above, is characterized in including: a plate-shaped member, which is made of a hard material in a substantially rectangular shape and is elastically supported by a position facing a bottom surface side of the striking surface; and two sensors, which are disposed on a surface side of the plate-shaped member and detect a vibration due to striking on the striking surface, wherein the two sensors are connected to electrically combine detection signals detected by the sensors and output the same.
US09006542B1 Maize inbred PH1VTZ
A novel maize variety designated PH1VTZ and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1VTZ with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1VTZ through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1VTZ or a locus conversion of PH1VTZ with another maize variety.
US09006536B1 Sorghum inbred PHA4CZQIT
A novel sorghum variety designated PHA4CZQIT and seed, plants and plant parts thereof. Methods for producing a plant that comprise crossing sorghum variety PHA4CZQIT with another plant. Methods for producing a plant containing in its genetic material one or more traits introgressed into PHA4CZQIT through backcross conversion and/or transformation, and to the sorghum seed, plant and plant part produced thereby. Hybrid sorghum seed, plant or plant part produced by crossing the sorghum variety PHA4CZQIT or a locus conversion of PHA4CZQIT with another sorghum variety.
US09006534B1 Soybean cultivar S120115
A soybean cultivar designated S120115 is disclosed. The invention relates to the seeds of soybean cultivar S120115, to the plants of soybean cultivar S120115, to the plant parts of soybean cultivar S120115, and to methods for producing progeny of soybean cultivar S120115. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar S120115. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar S120115, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar S120115 with another soybean cultivar.
US09006532B2 Soybean variety DLL1348
The soybean variety DLL1348 is disclosed. The invention relates to seeds, plants, plant cells, plant tissue, harvested products and soybean lint as well as to hybrid soybean plants and seeds obtained by repeatedly crossing plants of variety DLL1348 with other plants. The invention also relates to plants and varieties produced by the method of essential derivation from plants of DLL1348 and to plants of DLL1348 reproduced by vegetative methods, including but not limited to tissue culture of regenerable cells or tissue from DLL1348.
US09006531B2 Soybean variety DLL1069
The soybean variety DLL1069 is disclosed. The invention relates to seeds, plants, plant cells, plant tissue, harvested products and soybean lint as well as to hybrid soybean plants and seeds obtained by repeatedly crossing plants of variety DLL1069 with other plants. The invention also relates to plants and varieties produced by the method of essential derivation from plants of DLL1069 and to plants of DLL1069 reproduced by vegetative methods, including but not limited to tissue culture of regenerable cells or tissue from DLL1069.
US09006528B2 Soybean cultivar SJ1012389
The present invention is in the field of soybean variety SJ1012389 breeding and development. The present invention particularly relates to the soybean variety SJ1012389 and its progeny, and methods of making SJ1012389.
US09006527B2 Soybean cultivar SJ1012347
The present invention is in the field of soybean variety SJ1012347 breeding and development. The present invention particularly relates to the soybean variety SJ1012347 and its progeny, and methods of making SJ1012347.
US09006516B2 Hybrid carrot variety nun 85021 cac
The present invention relates to plants of a carrot variety NUN 85021 CAC and seeds and progeny thereof. The invention further relates to methods for producing a carrot plant by traditional breeding methods. The invention further relates to a method for producing a carrot plant containing in its genetic material one or more transgenes.
US09006515B2 Pollen preferred promoters and methods of use
Compositions and methods for regulating expression of heterologous nucleotide sequences in a plant are provided. Compositions include nucleotide sequences encompasses a strong pollen preferred promoter which drives strong, specific expression of gene products in pollen. Also provided is a method for expressing a heterologous nucleotide sequence in a plant using a promoter sequence disclosed herein.
US09006514B2 Plant membrane O-acyl transferase (MBOAT) family protein sequences and their uses for altering fatty acid compositions
This invention is in the field of biotechnology, in particular, this pertains to polynucleotide sequences encoding membrane bound O-acyltransferase genes and the use of these acyltransferases for altering fatty acid profiles in oilseed plants. Methods for increasing elongation and desaturation conversion efficiencies are also disclosed.
US09006512B1 Maize inbred PH17W6
A novel maize variety designated PH17W6 and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH17W6 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH17W6 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH17W6 or a locus conversion of PH17W6 with another maize variety.
US09006509B2 Absorbent article with high quality ink jet image produced at line speed
A mass produced absorbent article having an image of a quality that is commercially acceptable. The image is produced by ink jet printheads applying ink to a web moving at high speed under the jets in the course of manufacturing the article. The image is printed at low resolution but is characterized in part by a higher coverage area ratio and brightness.
US09006503B2 Organic electroluminescence devices containing substituted benzo[C]phenanthrenes
The present invention relates to substituted benzo[c]phenanthrene derivatives and to the production and to the use thereof in electronic devices, and to the electronic devices themselves. The present invention relates in particular an electronic device containing 10-benzo[c]phenanthrene derivatives of, e.g., formula (II) substituted with at least one aromatic unit or at least one diarylamino unit.
US09006492B2 Process for depolymerizing polysulfides and the preparation of bis-mercapto-diethers
The invention related to a process for the preparation of a bismercaptodiether by reacting a polysulfide with a monothiol in the presence of a base and to a process for the depolymerization of a polysulfide by reacting said polysulfide with a monothiol in the presence of a base. These processes enable the preparation of bismercaptodiethers without inorganic salt formation.
US09006487B2 Amine-containing lipids and uses thereof
Nitrogen-containing lipids prepared from the conjugate addition of amines to acrylates, acrylamides, or other carbon-carbon double bonds conjugated to electron-withdrawing groups are described. Methods of preparing these lipids from commercially available starting materials are also provided. These amine-containing lipids or salts forms of these lipids are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the amino moiety of these lipids, they are particularly suited for the delivery of polynucleotides. Complexes or nanoparticles containing the inventive lipid and polynucleotide have been prepared. The inventive lipids may also be used to in preparing microparticle for drug delivery. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings.
US09006485B2 Aniline type compounds
The present invention relates to compounds of the formula (I) wherein R1 and R2 independently of one another are hydrogen, C1-C10-alkyl, C1-C10-haloalkyl, C3-C10-cycloalkyl, C3-C10-halocycloalkyl, C2-C10-alkenyl, C2-C10-haloalkenyl or together represent an aliphatic chain, or the like; R3 is halogen, cyano, C1-C8-alkyl, C1-C8-haloalkyl, C3-C8-cycloalkyl, C3-C8-halocycloalkyl, C2-C8-alkenyl, C2-C8-haloalkenyl, C1-C8-alkoxy, phenyl, or the like; R4 is hydrogen, C1-C10-alkyl, C1-C10-haloalkyl, C3-C8-cycloalkyl, C3-C8-halocycloalkyl, C2-C10-alkenyl, C2-C10-haloalkenyl, phenyl, or the like; t is 0 or 1; p is 0, 1, 2, 3 or 4. The present invention also relates to a process for preparing a compound of the formula (I) which comprises reacting a compound of the formula II with a compound of the formulae III or IV: where t, p, R1 R3, R3 and R4 are as defined in any of claims 1 to 6 and where A− is an equivalent of an anion having a pKB of at least 10 (determined under standard conditions in water).
US09006484B2 Polymer having bis(diphenylphosphino)binaphthyl groups
A polymer having bis(diphenylphosphino)binaphthyl groups that can be used as a catalyst for an addition reaction, especially an asymmetric 1,4-addition reaction, or a reduction reaction, especially an asymmetric reduction reaction, and that can be easily recovered and recycled. The polymer having the bis(diphenylphosphino)binaphthyl groups is one resulting from repetition of a racemic or optically active 2,2′-bis(diphenylphosphino)-1,1′-binaphthyl compound substituted at 5-position thereof with an unsaturated terminal of one (meth)acryloyl group of a compound having multiple (meth)acryloyl groups, that another 2,2′-bis(diphenylphosphino)-1,1′-binaphthyl compound of a next unit is substituted at 5′-position thereof with an unsaturated terminal of another (meth)acryloyl group of the compound having multiple (meth)acryloyl groups so as to have a molecular weight of 1500 to 10000. The reduction catalyst comprises this polymer and a transition metal.
US09006482B2 Process for preparing methylene bis-(dialkylamino-dithioformate) in one step
A process for preparing methylene bis-(dialkylamino-dithioformate) in one step includes: simultaneously feeding all or part of four raw materials: dialkylamine, an aqueous solution of sodium hydroxide, dichloromethane and carbon disulfide through a constant-flow pump into a continuous flow reactor; performing the reactions in the continuous flow reactor under a temperature of 10 to 100° C. and with a residence time of 10 to 100 s; simply separating of the obtained reaction products to give the final product. The process synthesizes the product in one step by using the continuous flow reactor. The rapid mass transfer and heat transfer in the continuous flow reactor promote the main reaction, reduce side reactions, improve the product color, and shorten the operation time. Moreover, the yield is relatively high and the quality of the final product meets the requirements.
US09006481B2 Process and apparatus for preparing isocyanates
The invention relates to a process for preparing isocyanates by reacting the corresponding amines with phosgene in the gas phase, optionally in the presence of an inert medium, in which phosgene and amine are first evaporated and then superheated further to reaction temperature, and the superheated phosgene and amine are mixed and fed to a reactor in which the phosgene and the amine are converted to the isocyanate, wherein the residence time of the phosgene at temperatures greater than 300° C. is not more than 5 s, and/or the temperature of heat transfer surfaces in contact with phosgene is not more than 20 K above the phosgene temperature to be established. The invention further relates to an apparatus for preparing isocyanates by reacting the corresponding amines with phosgene in the gas phase.
US09006479B2 Process for preparing polyol esters
The present invention relates to a process for preparing polyol esters by reacting polyols with linear or branched aliphatic monocarbocxylic acids having 3 to 20 carbon atoms, the reaction taking place in the presence of a Lewis acid comprising at least one element from groups 4 to 14 of the Periodic Table of the Elements as catalyst, and in the presence of an adsorbent, the reaction product being subjected subsequently to a steam treatment.
US09006478B2 Diurethane gelators for curable ink applications
The disclosure provides a diurethane gelator having the structure of Formula I. wherein R1 and R1′ each, independently of the other, is a C1-C22 saturated aliphatic hydrocarbon group selected from the group consisting of (1) linear aliphatic groups, (2) branched aliphatic groups, (3) cyclic aliphatic groups, (4) aliphatic groups containing both cyclic and acyclic portions, any carbon atom of the saturated aliphatic hydrocarbon group may be optionally substituted with an alkyl group (cyclic or acyclic), wherein (1) and (2) groups have a carbon number of from about 1 to about 22 carbons, and wherein (3) and (4) groups have a carbon number of from about 4 to about 10 carbons; and X is selected from the group consisting of: (i) an alkylene group, (ii) an arylene group, (iii) an arylalkylene group, and (iv) an alkylarylene group.
US09006475B2 Organometallic compound preparation
A method of continuously manufacturing organometallic compounds is provided where two or more reactants are conveyed to a reactor having a laminar flow contacting zone, a heat transfer zone, and a mixing zone having a turbulence-promoting device; and causing the reactants to form the organometallic compound.
US09006474B2 Method for producing refined a fat or oil
A method for manufacturing a refined fat or oil, including: carrying out a first steam treatment of bringing a fat or oil into contact with water vapor; and subsequently carrying out a second steam treatment of bringing the fat or oil having a temperature lower by 10° C. or more than a temperature of the fat or oil in the first steam treatment into contact with water vapor in the presence of an organic acid.
US09006472B2 Methods for the synthesis of 13C labeled plasmalogen
A method for preparing 13C labeled plasmalogens as represented by Formula B: The method involves producing a 13C labeled cyclic plasmalogen precursor of Formula A: and conversion of the precursor to a plasmalogen of Formula B.
US09006470B2 Method of synthesizing low color furan diesters
The present invention relates to a method of synthesizing a low colored furan-2,5-dicarboxylate derivative plasticizer by utilizing purified FDCA (pFDCA), which has very low level 5-formyl furan-2-carboxyic acid (FFCA) and very low level colored bodies, and an alcohol.
US09006467B2 1,2,3-triazole containing artemisinin compounds and process for preparation thereof
The present invention relates to 1,2,3-triazole containing artemisinin compounds and process for preparation thereof. Described herein is the synthesis, bioassay results and usefulness of the artemisinin derived compounds resulting from 1,3-dipolar cycloaddition reaction of artemisinin derived azide or alkyne with aliphatic or aromatic diazides. These 1,2,3-triazole containing artemisinin derived compounds embodied in this document are found to be active against various cancer cell-lines.
US09006466B2 Use of coumarin derivatives for the preparation of drugs for treating skin diseases
A compound of formula (I-1) wherein n equals 0 or 1, Z represents O or S, R1 represents one group chosen among the group consisting of hydrogen, C1-C7 alkyl, substituted, or not, by a halogen, a hydroxyl or a —O—R12 group, wherein R12 is a C1-C7 alkyl, a group —CH2—O—CO—R5 wherein R5 is chosen among a hydrogen atom and a C1-C7 alkyl, substituted or not by at least one halogen, a group —O—R13, wherein R13 is chosen among hydrogen and a C1-C7 alkyl, an amine or a —CH2— amine, R′1 represents a group chosen among hydrogen and —O—R14, wherein R14 is chosen among hydrogen and a C1-C7 alkyl, and R2 is chosen among the group consisting of a C1-C7 alkyl, a C3-C6 cycloalkyl, an aryl group, and an heteroaryl group for the treatment of pathologies involving excess activity of at least one member of the kallikrein family.
US09006463B2 Slow release of organoboronic acids in cross-coupling reactions
A method of performing a chemical reaction includes reacting a compound selected from the group consisting of an organohalide and an organo-pseudohalide, and a protected organoboronic acid represented by formula (I) in a reaction mixture: R1—B-T  (I); where R1 represents an organic group, T represents a conformationally rigid protecting group, and B represents boron having sp3 hybridization. When unprotected, the corresponding organoboronic acid is unstable by the boronic acid neat stability test. The reaction mixture further includes a base having a pKB of at least 1 and a palladium catalyst. The method further includes forming a cross-coupled product in the reaction mixture.
US09006460B2 Process for preparing aminocyclohexyl ether compounds
The present invention relates to a process for preparing aminocyclohexyl ether compounds of Formula I: or the pharmaceutically acceptable salts and esters thereof. In particular, the instant invention is directed towards a process for preparing (1R,2R)-2-[(3R)-Hydroxypyrrolidinyl]-1-(3,4-dimethoxyphenethoxy)-cyclohexane as well as various intermediates.
US09006455B2 Hepatitis C virus inhibitors
The present disclosure relates to methods for making compounds useful in the treatment of Hepatitis C virus (HCV) infection.
US09006453B2 Process for preparation of zolmitriptan
The present invention provides a convenient and industrially viable process for preparation of Zolmitriptan (I) having desired purity. The invention specifically relates to a method for isolating (S)-4-(4-hydrazinobenzyl)-1,3-oxazolidin-2-one hydrochloride (IIIa) of desired purity by separating the undesired inorganic side products such as stannous hydroxide by manipulation of pH at different stages and finally treating with N,N-dimethylamino butyraldehyde diethyl acetal in an acidic medium to provide Zolmitriptan (I) conforming to regulatory specifications.
US09006451B1 2-anilinonicotinyl based chalcones useful as potential anticancer agents and process for preparation thereof
The present invention provides a compound of general formulae A useful as potential antitumor agents against human cancer cell lines and a process for the preparation thereof.
US09006450B2 Compounds, pharmaceutical compositions and uses thereof
The invention relates to new piperidine derivatives of the formula I to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.
US09006444B2 Phenyl carboxamide-containing spleen tyrosine kinase (SYK) inhibitors
The invention provides certain phenyl carboxamide-containing compounds of the Formula (I); or pharmaceutically acceptable salts thereof, wherein A and B are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase.
US09006443B2 Process for preparing quinoline-3-carboxamide derivatives
Disclosed herein is an improved, commercially viable and industrially advantageous process for the preparation of quinoline-3-carboxamide derivatives such as laquinimod, or a pharmaceutically acceptable salt thereof, in high yield and purity.
US09006441B2 Conjugate addition reactions using bifunctional cinchona-alkaloid-based catalysts
One aspect of the present invention relates to quinine-based and quinidine-based catalysts. Another aspect of the present invention relates to a method of preparing a chiral, non-racemic compound from a prochiral electron-deficient alkene, comprising the step of: reacting a prochiral electron-deficient alkene with a nucleophile in the presence of a catalyst; thereby producing a chiral, non-racemic compound; wherein said catalyst is a derivatized quinine or quinidine.
US09006440B2 Furopyridine derivatives
Compounds of the formula I in which R1 and R2 have the meanings indicated in Claim 1, are inhibitors of Syk, and can be employed, inter alia, for the treatment of rheumatoid arthritis and/or systemic lupus.
US09006439B2 Camptothecin derivatives having anti-tumor activity
Disclosed are novel camptothecin derivatives having anti-tumor activity (the basic structure thereof is as shown in the figure) and compositions of such compounds and use thereof. The compounds according to the present invention exhibit very good water solubility and stability, show good selectivity among drugs of the same category, and have a very high therapeutic index. Such compounds are promising as therapeutic agents for treating tumors.
US09006434B2 Crystals of glycine derivative and pharmaceutical use thereof
A crystal of (S,E)-2-(2,6-dichlorobenzamido)-5-[4-(methyl-pyrimidin-2-ylamino)phenyl-yl]pent-4-enoic acid has excellent chemical and physical stability, and a medical use thereof.
US09006433B2 Substituted pyrimidines
The present invention relates to substituted pyrimidines useful as HIF prolyl hydroxylase inhibitors to treat anemia and like conditions.
US09006426B2 Squaric acid derivatives as inhibitors of the nicotinamide
The present application discloses novel squaric acid derivatives of the formula A: from —C(═O)—, —S(═O)2—, —C(═S)— and —P(═O)(R5)—; B: -, —O—, —NR6— and —C(═O)—NR6—; D: -, —O—, —CR7R8— and —NR9; m=0-12; n=0-12; m+n=1-20; p=0-2; R1: heteroaryl, aryl; R2: H, C1-12-alkyl, C3-12-cycloalkyl, —[CH2CH2O]1-10—(C1-6-alkyl), C1-12-alkenyl, aryl, heterocyclyl, heteroaryl; R3: C1-12-alkyl, C3-12-cycloalkyl, —[CH2CH2O]1-10—(C1-6-alkyl), C1-12-alkenyl, aryl, heterocyclyl, heteroaryl; or R2 and R3: N-containing heterocyclic/heteroaromatic ring; R4 and R4*: H, C1-12-alkyl, C1-12-alkenyl; and pharmaceutically acceptable salts and prodrugs thereof, and their use in the treatment of diseases/conditions caused by an elevated level of NAMPRT (inflammatory and tissue repair disorders, particularly rheumatoid arthritis, inflammatory bowel disease, asthma and CPOD, osteoarthritis, osteoporosis and fibrotic diseases; dermatosis; autoimmune diseases including systemic lupus erythematosis, multiple sclerosis, psoriatic arthritis, ankylosing spondylitis, tissue and organ rejection, Alzheimer's disease, stroke, atherosclerosis, restenosis, diabetes, glomerulonephritis, cancer, cachexia, inflammation associated with infection and viral infections, adult respiratory distress syndrome, ataxia telengiectasia).
US09006417B2 Non-liposomal systems for nucleic acid delivery
The present invention provides novel, stable lipid particles having a non-lamellar structure and comprising one or more active agents or therapeutic agents, methods of making such lipid particles, and methods of delivering and/or administering such lipid particles. More particularly, the present invention provides stable nucleic acid-lipid particles (SNALP) that have a non-lamellar structure and that comprise a nucleic acid (such as one or more interfering RNA), methods of making the SNALP, and methods of delivering and/or administering the SNALP.
US09006414B2 Recombinant DNA for gene suppression
Anti-sense-oriented RNA gene suppression agents in the form of a loop of anti-sense-oriented RNA is produced in cells of transgenic organisms, e.g. plants, by transcription from a recombinant DNA construct which comprises in 5′ to 3′ order a promoter element operably linked to an anti-sense-oriented DNA element and a complementary DNA element.
US09006409B2 Methods of increasing secretion of polypeptides having biological activity
The present invention relates to methods for producing a secreted polypeptide having biological activity, comprising: (a) transforming a fungal host cell with a fusion protein construct encoding a fusion protein, which comprises: (i) a first polynucleotide encoding a signal peptide; (ii) a second polynucleotide encoding at least a catalytic domain of an endoglucanase or a portion thereof; and (iii) a third polynucleotide encoding at least a catalytic domain of a polypeptide having biological activity; wherein the signal peptide and at least the catalytic domain of the endoglucanase increases secretion of the polypeptide having biological activity compared to the absence of at least the catalytic domain of the endoglucanase; (b) cultivating the transformed fungal host cell under conditions suitable for production of the fusion protein; and (c) recovering the fusion protein, a component thereof, or a combination thereof, having biological activity, from the cultivation medium.
US09006400B2 Fibroblast growth factor-21-Fc fusion proteins
The invention relates to the identification of fusion proteins comprising polypeptide and protein variants of fibroblast growth factor 21 (FGF21) with improved pharmaceutical properties. Also disclosed are methods for treating FGF21-associated disorders, including metabolic conditions.
US09006397B2 FN14 binding proteins and uses thereof
The present disclosure provides proteins comprising antibody antigen binding domains that bind to Fn14 and uses thereof. The present disclosure also provides methods for treating wasting disorders, such as cachexia.
US09006395B2 Recombinant toxin fragments
A single polypeptide is provided which comprises first and second domains. The first domain enables the polypeptide to cleave one or more vesicle or plasma-membrane associated proteins essential to exocytosis, and the second domain enables the polypeptide to be translocated into a target cell or increases the solubility of the polypeptide, or both. The polypeptide thus combines useful properties of a clostridial toxin, such as a botulinum or tetanus toxin, without the toxicity associated with the natural molecule. The polypeptide can also contain a third domain that targets it to a specific cell, rendering the polypeptide useful in inhibition of exocytosis in target cells. Fusion proteins comprising the polypeptide, nucleic acids encoding the polypeptide and methods of making the polypeptide are also provided. Controlled activation of the polypeptide, is possible and the polypeptide can be incorporated into vaccines and toxin assays.
US09006391B2 Method for the preparation of cyclopeptides
The present invention relates to a method for preparing cyclopeptides by means of protection with a substituted boronic acid. The present invention also discloses novel boronate esters of cyclopeptides of general formula (8).
US09006389B2 Repeat protein from collection of repeat proteins comprising repeat modules
A repeat protein from a collection of repeat proteins, wherein each repeat protein of said collection comprises a repeat domain, which comprises a set of consecutive repeat modules, wherein the repeat modules have the same fold and stack tightly to create a superhelical structure having a joint hydrophobic core, wherein each of the repeat modules is derived from one or more repeat units and wherein the repeat units comprise framework residues, which contribute to the folding topology of the repeat unit or contribute to an interaction with a neighboring repeat unit, and target interaction residues, which contribute to an interaction with a target substance, wherein the repeat proteins of the collection differ from other repeat proteins in the collection in at least one amino acid position of the repeat modules is described as are related pharmaceuticals and nucleic acid molecules.
US09006387B2 Anti-viral compounds
Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
US09006385B2 Elastomeric epoxy materials and the use thereof
Thermoset elastomer compositions are disclosed. Such elastomers are the reaction product of (a) an ambient temperature liquid epoxy-terminated prepolymer formed by reacting a polyoxyalkyleneamine having a molecular weight of from 3000 to 20,000 with an excess of epoxide, wherein the polyoxyalkyleneamine has at least 3 active hydrogen atoms and (b) a curing agent comprising at least one amine or polyamine having an equivalent weight of less than 200 and having 2 to 5 active hydrogen atoms. Such elastomers can be used in applications such as for sealants, adhesives, coatings, gaskets, jointing and cast elastomers.
US09006383B2 Method for producing copolymer of diallylamine and sulfur dioxide
Provided is a process for producing a copolymer of a diallylamine and sulfur dioxide which copolymer has a higher molecular weight and water-solubility than that obtained by a conventional production process by copolymerizing the diallylamine and sulfur dioxide in the presence of an acid and a radical polymerization initiator in a polar solvent.
US09006382B2 Synthesis polyesters with precisely sequenced two or more structural units
The present invention related to compositions and methods of producing polyesters with two and/or more different structural units and the materials of polyesters with structure sequence exactly specified therefore produced, and various articles produced from such exactly sequenced polyesters. More particularly, homogeneous copolymers with precisely defined sequences of various hydroxyl acids and their derivatives are produced according to the present invention.
US09006378B2 Color stable thermoplastic composition
A plastic article formed from a thermoplastic composition including a polycarbonate having repeating structural carbonate units according to the formula: in which at least 60 percent of the total number of R1 groups contain aromatic moieties and the balance thereof are aliphatic, alicyclic, or aromatic. The composition also includes an epoxy additive having at least two epoxy groups per molecule and a phenolic diphosphite derived from pentaerythritol. The thermoplastic composition exhibits a dE (2000 hrs.) value of less than 1.5 after 2000 hours of heat aging at 130° C., measured according ISO 11664-4:2008(E)/CIE S 014-4/E:2007 using CIE illuminant D65 and a 2.5 mm thick molded plaque of the thermoplastic composition.
US09006377B2 Resin composition and uses of the same
A resin composition is provided. The resin composition comprises: an epoxy resin; and a hardener, which is a stable solution obtainable from the following steps: (a) adding a N,O-heterocyclic compound of formula I or II and a DOPO-based compound into an organic solvent to provide a reaction solution: wherein R1 to R3, W1, W2, m, n, p and q are as defined in the specification; (b) heating the reaction solution to carry out a ring-opening reaction to provide a polymer solution; and (c) cooling the polymer solution to obtain the stable solution, wherein the organic solvent is unreactive to the N,O-heterocyclic compound and the DOPO-based compound, and the amounts of the DOPO-based compound and the hardener are as defined in the specification.
US09006376B2 Germole containing conjugated molecules and polymers
Embodiments of the invention are directed to Ge comprising heterocyclic compounds which can be used for the preparation of homopolymers and copolymers. The copolymers can be donor-acceptor (DA) alternating copolymers where the donor unit is a Ge comprising heterocyclic unit. The polymers can be used as materials in solar cells and other photovoltaic devices, transistors, diodes, light emitting devices (LEDs), conductors, supercapacitors, batteries, and electrochromic devices.
US09006375B2 Accelerated cure of isocyanate terminated prepolymers
A method for preparing a polyurethane elastomer, the method comprising mixing an isocyanate terminated prepolymer and a nitrogen-containing organic salt to form a prepolymer mixture and reacting the prepolymer in the prepolymer mixture with a methylenedianiline metal salt coordination complex chain extender to form the polyurethane elastome. The nitrogen-containing organic salt is selected from the group consisting of an ammonium salt, an imidazolium salt, a pyridinium salt, a pyrrolidinium salt, a piperidinium salt, and a morpholinium salt.
US09006374B2 Curable composition
This application relates to a curable composition and its use. The curable composition may exhibit excellent processibility and workability. The curable composition has excellent light extraction efficiency, crack resistance, hardness, thermal and shock resistance and an adhesive property after curing. The curable composition may provide a cured product exhibiting stable durability and reliability under severe conditions for a long time and having no whitening and surface stickiness.
US09006370B1 Transparent abrasion-resistant coatings for plastic substrates and water-based method to prepare same
Optically clear abrasion (or scratch) and chemical-resistant coatings for use on plastic surfaces and methods for making the coating. These coatings can also be used on metallic substrates for improving their hardness and anti-corrosion (or barrier) properties. The coating composition includes at least one silane which has at least one non-hydrolyzable radical containing an epoxy group, at least one aluminum alkoxide, at least one hydrolyzable silicon compound, at least one acid, and water. The coating composition is a molecular composite formulation and is free from particulate materials.
US09006369B2 Water based lignin epoxy resins, methods of using and making the same
Water based lignoepoxy resins, and methods for their preparation and use are provided. Methods of making lignoepoxy resins without the use of volatile organic compounds are also provided.
US09006368B2 Propylene-based terpolymers for film
A propylene/ethylene/1-hexene terpolymer containing from 1.0 wt % to 2.5 wt %, of ethylene derived units and from 2.0 wt % to 3.5 wt % of 1-hexene derived units, the sum of the amounts of propylene, ethylene and 1-.hexene derived units being 100, having the following features: a) the amount (Wt %) of 1-hexene (C6) and the amount (Wt %) of ethylene (C2) fulfill the following relation (i): 0.5
US09006360B2 Controlled-release amine-catalyzed, sulfur-containing polymer and epdxy compositions
Compositions comprising sulfur-containing polymers such as polythioethers and polysulfides, polyepoxides, and controlled-release amine catalysts useful in aerospace sealant applications are disclosed. The compositions exhibit extended pot life and the rate of curing can be tailored for specific applications.
US09006359B2 Imbibing process for contact lens surface modification
Medical devices having a wettable, biocompatible surface are described herein. Processes for producing such devices are also described.
US09006357B2 Curable polysiloxane composition
A curable composition comprises (a) at least one polyorganosiloxane, fluorinated polyorganosiloxane, or combination thereof comprising reactive silane functionality comprising at least two hydroxysilyl moieties; (b) at least one polyorganosiloxane, fluorinated polyorganosiloxane, or combination thereof comprising reactive silane functionality comprising at least two hydrosilyl moieties; and (c) a catalyst composition comprising (1) at least one base selected from amidines, guanidines, phosphazenes, proazaphosphatranes, and combinations thereof, and (2) at least one Lewis acid; wherein at least one of the components (a) and (b) has an average reactive silane functionality of at least three.
US09006354B2 Composite composition of inorganic oxide particles and silicone resin, method of manufacturing the same, transparent composite, and method of manufacturing the same
A method of manufacturing a composite composition, having: bonding a dispersant to the surfaces of inorganic oxide particles to provide dispersibility in a hydrophobic solvent to the inorganic oxide particles, and then dispersing the inorganic oxide particles in a hydrophobic solvent; substituting the dispersant bonded to the surfaces of the inorganic oxide particles with a surface modifier, which is a polydimethylsiloxane-skeleton polymer having one functional group at one terminal end, in the hydrophobic solvent in which the organic oxide particles are dispersed to bond the functional group of the polydimethylsiloxane-skeleton polymer to the surfaces of the inorganic oxide particles; and conjugating a silicone resin and the inorganic oxide particles obtained in the previous step, wherein the surface thereof is modified by bonding the polydimethylsiloxane-skeleton polymer having one functional group at one terminal end thereof, to obtain a composite composition.
US09006343B2 Blends of co-precipitated hydrogenated ethylene-dicyclopentadiene and elastomeric polymers to provide impact modified structural polyolefins
Disclosed is the preparation of compositions which are blends of certain types of hydrogenated ethylene-dicyclopentadiene (E/DCPD) copolymers in combination with elastomeric polymers. An E/DCPD copolymer and an elastomeric polymer are co-dissolved in a common liquid reaction medium which is then subjected to hydrogenation conditions. These hydrogenation conditions serve to hydrogenate in-situ at least a portion of the residual double bonds of the E/DCPD copolymer component and possibly also eliminate any residual unsaturation which might be present in the elastomeric polymers. This combination of materials which has been hydrogenated in-situ can then be co-precipitated to form a polymer composition which can be molded into polyolefin materials of improved structural, thermal and mechanical properties with desirable impact resistance.
US09006342B2 Bimodal polyethylene composition and articles made therefrom
The invention relates to a polyethylene composition with a bimodal molecular weight distribution and articles made therefrom, such as high topload blow moldings and transmission and distribution pipes. The composition comprises a low-molecular-weight (LMW) ethylene homopolymer component and a homogeneous, high-molecular-weight (HMW) ethylene interpolymer component, wherein the LMW component is characterized as having a molecular weight distribution, MWDL, of less than about 8. The composition is characterized as having a bimodal molecular weight distribution, and a ductile-brittle transition temperature, Tdb, of less than −20° C. In some embodiments, the HMW component is characterized by a reverse comonomer distribution.
US09006341B2 Polyolefin fibres
A polyolefin composition comprising: A) 20-95 wt % of a propylene homo-polymer or a crystalline co-polymer of propylene with ethylene and/or an alpha-olefin having 4-10 carbon atoms, containing 85 wt % or more of propylene, having an isotactic index equal to or higher than 80; B) 5-80 wt % of a copolymer of butene-1 with ethylene and/or an alpha-olefin having 3-10 carbon atoms having: a content of butene-1 derived units of 80 wt % wt or more, molecular weight distribution Mw/Mn of less than 3 flexural modulus of 60 MPa or less. Fibres and spun bond (woven non woven), disposable sanitary items (e.g. diapers) thereof.
US09006337B2 Method for making a polymer, a polymer article, a biodevice, and cyclic carbonate
The present invention relates to a method for making a polymer wherein during ring opening polymerisation is incorporated into the polymer chain at least one cyclic (alkyl) carbonate monomer having the formula (1) wherein Y is optional and represents the residue of a sulfhydryl reacted group, X represents a functional group reactive with a sulfhydryl group, L=—[CH2]n with n=0-10, or L=—[CH2]p-S—S—[CH2]q with p and q are 0-5 or L=-[PEG]- with PEG is a group that comprises a —[CH2CH2O]m-group with m=1-200, and R2 is hydrogen, methyl or ethyl. Optionally a cyclic (alkyl) acryloyl carbonate, or other additional monomer A may be used as comonomer. The polymer may be formed into a polymer article, such as a polymer film, such as a coating and modified and/or cross linked, to a polymer or polymer article obtainable, and to a biodevice, their use, and to the cyclic (alkyl)carbonates.
US09006336B2 Curable polysiloxane coating composition
A curable composition comprises (a) at least one polyorganosiloxane, fluorinated polyorganosiloxane, or combination thereof comprising reactive silane functionality comprising at least two hydroxysilyl moieties; (b) at least one polyorganosiloxane, fluorinated polyorganosiloxane, or combination thereof comprising reactive silane functionality comprising at least two hydrosilyl moieties; and (c) a catalyst composition comprising at least one carbene; wherein at least one of the components (a) and (b) has an average reactive silane functionality of at least three.
US09006333B2 Method for manufacturing fine polytetrafluoroethylene powder
A method for manufacturing a polytetrafluoroethylene fine powder characterized by including the steps of (1) preparing an aqueous dispersion containing polytetrafluoroethylene, water, and a surfactant (A); (2) coagulating the polytetrafluoroethylene in the aqueous dispersion by agitating the aqueous dispersion with a discharge flow-type impeller; (3) collecting a wet powder of the polytetrafluoroethylene; and (4) drying the wet powder of the polytetrafluoroethylene.
US09006331B2 Latex particles imbibed with a thermoplastic polymer
The present invention relates to a process for imbibing a step-growth polymer into thermoplastic latex particles and a composition made by such a process. The composition is useful, for example, as a coating, an adhesive, a sealant, a primer, a caulk, a stain, or a filler for a variety of substrates.
US09006330B2 Thermal stabilizer-free thermoplastic resin composition and method of preparing the same
Disclosed are a thermal stabilizer-free thermoplastic resin composition and a method of preparing the same. The thermal stabilizer-free thermoplastic resin composition has superior impact resistance, falling ball impact resistance and gloss without using a separate thermal stabilizer. Particularly, the thermal stabilizer-free thermoplastic resin composition improves production efficiency when applied to a squeezing dehydrator because the thermoplastic resin composition is prepared without using a drying process.
US09006327B2 Process for preparing precomposites based on nanotubes, particularly carbon nanotubes
The subject of the present invention is a process for preparing a precomposite based on nanotubes, comprising bringing said nanotubes into contact with at least one given plasticizing agent.It also relates to a precomposite thus obtained, and to its use for conferring at least one electrical, mechanical and/or thermal property on a polymer material.It also relates to the use of a given plasticizer for improving the dispersion and/or mechanical properties and/or electrical conductivity and/or thermal conductivity of nanotubes in a polymer matrix.
US09006321B2 Composition made from natural rubber and a polyimine compound
Reinforced rubber composition, exhibiting improved hysteresis, based on at least (a) an elastomeric matrix predominantly based on natural rubber, (b) a reinforcing filler and (c) a specific polyimine compound in a small proportion, preferably ranging from 1 to 5 mmol per 100 g of elastomer.This rubber composition is intended, for example, for the manufacture of a semi-finished rubber product intended for the tires of motor vehicles.
US09006319B2 Hydrostable polyetherimide blends, methods of manufacture, and articles formed therefrom
A composition comprising, based on the total weight of the composition, from 10 to 90 wt. % of a polyetherimide with a weight average molecular weight from 10,000 to 80,000 Daltons; from 10 to 90 wt. % of a polymer selected from polycarbonates, polyester-polycarbonates, polyalkylene terephthalates, or a combination thereof, from 0.005 to 1 wt. % of a hydrotalcite having a particle size of less than 10 micrometer and a magnesium oxide to aluminum oxide mole ratio of 1.0 to 5.0; from 0.01 to 1.0 wt. % of a phosphorus-containing stabilizer; from 0.01 to 1.00 wt. % of a hindered phenol stabilizer; optionally, from 0 to 3 wt. % of a polyolefin; and optionally, from 0 to 5 wt. % of an inorganic metal oxide.
US09006315B2 Thermoplastic starch compositions
The present invention relates to improvements in prevention of discoloration of thermoplastic starch materials and their blends with other thermoplastic materials.
US09006314B2 Thermoset particles with enhanced crosslinking, production, and their use in oil and natural gas drilling applications
Use of two different methods, either each by itself or in combination, to enhance the stiffness, strength, maximum possible use temperature, and environmental resistance of thermoset polymer particles is disclosed. One method is the application of post-polymerization process steps (and especially heat treatment) to advance the curing reaction and to thus obtain a more densely crosslinked polymer network. The other method is the incorporation of nanofillers, resulting in a heterogeneous “nanocomposite” morphology. Nanofiller incorporation and post-polymerization heat treatment can also be combined to obtain the benefits of both methods simultaneously. The present invention relates to the development of thermoset nanocomposite particles. Optional further improvement of the heat resistance and environmental resistance of said particles via post-polymerization heat treatment; processes for the manufacture of said particles; and use of said particles in the construction, drilling, completion and/or fracture stimulation of oil and natural gas wells are described.
US09006308B2 Reinforcing filler for rubber
The present invention describes a reinforcing filler for rubber comprising the synergistic combination of precipitated silica with a pore structure defined by a maximum between 25 nm and 35 nm, a total pore volume between 1.3 cm3/g and 1.6 cm3/g, and a compression factor between 1.3 10−2 and 2.3 10−2 MPa−1, and at least one crystalline alkaline silicate corresponding to the general formula of the crystalline alkaline silicates, said crystalline alkaline silicate being swelled and/or layered in the presence of an organic cationic compound in the form of ammonium salt of the +NR4 type according to the formula [CnH2n+1N(CH3)3]+. The rubber formulation obtained by this reinforcing filler composition does present a great reduction of energy dissipated in the tread without compromising the abrasion resistance and elastic modulus properties.
US09006306B2 Flame retardant polymer compositions
In one aspect, the invention relates to crosslinkable, flame retardant polymer compositions are provided comprising a polyamide or polyester; a flame retardant system; a crosslinking agent; and a flame retardant system coagent. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
US09006304B2 Aqueous polyurethane-polyurea dispersions
The present invention relates to aqueous polyurethane-polyurea dispersions which stabilize a foam—produced by mechanical expansion—without addition of further foam-stabilizing components in such a way that aqueous foams are obtainable which are stable both during temporary storage and during processing, so that they can be applied in the form of foam also by customary application methods and substantially retain the foam structure even after drying.
US09006299B2 Method for removal of metal ions from an aqueous solution
The present invention relates to a method for removal of metal ions from an aqueous solution, which comprises contacting the aqueous solution with a phosphazene-formaldehyde resin as well as an ion exchange resin comprising a phosphazene-formaldehyde resin.
US09006294B2 Oral pharmaceutical formulation of pelubiprofen with improved dissolution rate and stability
Disclosed is an oral pharmaceutical formulation of pelubiprofen which is improved in dissolution rate and stability. As a result of an improvement in the dissolution rate of pelubiprofen, the oral pharmaceutical formulation can show high bioavailability and thus exert pharmacological effects thereof rapidly. It also can be stored with high stability as a result of the minimal generation of related compounds.
US09006293B2 Compositions containing xanthohumol-cyclodextrin complexes
The invention provides compositions comprising xanthohumol/cyclodextrin complexes that are water soluble and that have increased stability relative to xanthohumol alone.
US09006292B2 Metadichol® liquid and gel nanoparticle formulations
The present invention provides methods of regulating physiological and metabolic parameters and of treating diseases by administering metadichol to a subject in need of such regulation and/or treatment. Metadichol can be administered as a liquid or gel formulation.
US09006290B2 Cycloalkyl-hydroxyl compounds and compositions for cholesterol management and related uses
The present invention relates to novel cycloalkyl-hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer's Disease, cancer, cardiovascular disease, diabetic nephropathy, diabetic retinopathy, a disorder of glucose metabolism, dyslipidemia, dyslipoproteinemia, hypertension, impotence, inflammation, insulin resistance, lipid elimination in bile, obesity, oxysterol elimination in bile, pancreatitis, Parkinson's disease, a peroxisome proliferator activated receptor-associated disorder, phospholipid elimination in bile, renal disease, septicemia, Syndrome X, thrombotic disorder. Compounds and methods of the invention can also be used to modulate C reactive protein or enhance bile production in a patient. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents.
US09006278B2 Controlled release systems of pluribioactive antifungal drugs and applications thereof
Controlled release systems release at least one pluribioactive antifungal drug exhibiting at least one additional bioactivity from the group consisting of spermiostatic, antineoplastic, antibacterial, antirestenotic and antiviral activities. The drug release system is designed for use as a spermiostatic contraceptive, intravaginal ringed-mesh which may also exhibit antiviral activity, an in situ-forming implant for treating different forms of cancer and topical film for treating or preventing bacterial and fungal infections.
US09006275B2 Compounds as cannabinoid receptor ligands and uses thereof
The present invention relates to compounds of formula (I), or pharmaceutically acceptable salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1, R2, R3, R4, and L2, are defined in the specification, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
US09006272B2 Pharmaceutical compositions and method for treating inflammation in cattle and other animals
Novel transdermal preparations combining a non-steroidal anti-inflammatory drug (NSAID) such as flunixin, are disclosed. Methods for using and administering such preparation in the treatment of inflammatory conditions in bovines, including bovine respiratory disease, are also disclosed.
US09006269B2 Azetidine derivatives
Compounds of formula (I) are inhibitors of fatty acid amide hydrolase, (FAAH), and which are useful in the treatment of diseases or medical conditions which benefit from inhibition of FAAH activity, such as anxiety, depression pain, inflammation, and eating, sleep, neurodegenerative and movement disorders: Wherein Ar1 is optionally substituted phenyl or optionally substituted monocyclic heteroaryl having 5 or 6 ring atoms; Ar2 is optionally substituted phenyl, optionally substituted monocyclic heteroaryl having 5 or 6 ring atoms or optionally substituted fused bicyclic heteroaryl having 5 or 6 ring atoms in each fused ring; and Ar3 is a divalent radical selected from the group consisting of optionally substituted phenylene and optionally substituted monocyclic heteroarylene radicals having 5 or 6 ring atoms.
US09006268B2 Prolylcarboxypeptidase inhibitors
Compounds of structural formula I are inhibitors of prolylcarboxypeptidase (PrCP). The compounds of the present invention are useful for the prevention and treatment of conditions related to the enzymatic activity of PrCP such as abnormal metabolism, including obesity; diabetes; metabolic syndrome; obesity related disorders; and diabetes related disorders.
US09006265B2 Substituted fused pyrimidinones and dihydropyrimidinones
The use of substituted fused pyrimidinones and dihydropyrimidinones of the formula (I) or salts thereof where the radicals of the formula (I) are each as defined in the description, for enhancing stress tolerance in plants to abiotic stress, and for invigorating plant growth and/or for increasing plant yield.
US09006264B2 Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
Imidazo-quinoline, -pyridine, and -naphthyridine ring systems (particularly quinolines, tetrahydroquinolines, pyridines, [1,5]naphthyridines, [1,5]tetrahydronaphthyridines) substituted at the 1-position with a cyclic substituent, pharmaceutical compositions containing the compounds, methods of making these compounds, and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
US09006263B2 Compounds and methods for treatment of hypertension
Hydrogenated pyrido[4,3-b]indoles, pyrido[3,4-b]indoles and azepino[4,5-b]indoles are described. The compounds may bind to and are adrenergic receptor α2B antagonists. The compounds may also bind to and antagonize adrenergic receptor α1B. The compounds may find use in therapy, e.g., to (i) reduce blood pressure and/or (ii) promote renal blood flow and/or (iii) decrease or inhibit sodium reabsorption. The compounds may also be used to treat diseases or conditions that are, or are expected to be, responsive to a decrease in blood pressure. Use of the compounds to treat cardiovascular and renal disorders is particularly described.
US09006261B2 Fluorescent perylene derivatives for direct detection of heparin
The invention relates to a perylene diimide derivative and to an in vitro method for preparing the same. In addition, the invention relates to a method for detecting heparin in a sample using perylene diimide derivatives, wherein the interaction of the perylene diimide derivative with heparin modulates the intensity of the fluorescent signal of the mixture compared to the solution. The invention also comprises a diagnostic kit for detecting heparin in a sample in vitro, comprising the perylene diimide derivative, as well as the use of the perylene diimide derivative for neutralizing the anticoagulant activity of heparin.
US09006258B2 Method of treating female sexual dysfunction with a PDE1 inhibitor
The present invention relates to a new use for compounds that inhibit phosphodiesterase 1 (PDE1), e.g., that inhibit PDE1-mediated suppression of the dopamine D1 receptor and/or progesterone signaling pathways, including, e.g., methods of treatment or prophylaxis for conditions which may be ameliorated by enhancing the progesterone signaling response, particularly female sexual dysfunction.
US09006256B2 Antitumor agent for thyroid cancer
The present invention provides pharmaceutical compositions and therapeutic methods for treating diseases such as multiple endocrine neoplasia type IIA, multiple endocrine neoplasia type IIB, familial medullary thyroid carcinoma, thyroid carcinoma, papillary thyroid carcinoma, sporadic medullary thyroid carcinoma, Hirschsprung disease, pheochromocytoma, parathyroid hyperplasia and mucosal neuromas of the gastrointestinal tract. The therapeutic methods and pharmaceutical compositions use a RET kinase inhibiting substance, such as 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7-methoxy-6-quinolinecarboxamide and pharmacologically acceptable salts thereof, and involve a step of administering the RET kinase inhibiting substance to a patient.
US09006243B2 HIV inhibiting 6-substituted pyrimidines
HIV replication inhibitors of formula R1 is hydrogen; aryl; formyl; C1-6alkylcarbonyl; C1-6alkyl; C1-6alkyloxycarbonyl; R2, R3, R6 and R7 are hydrogen; hydroxy; halo; C3-7cycloalkyl; C1-6alkyloxy; carboxyl; C1-6alkyloxycarbonyl; cyano; nitro; amino; mono- or di(C1-6alkyl)amino; polyhaloC1-6alkyl; polyhaloC1-6alkyloxy; —C(═O)R9; optionally substituted C1-6alkyl, C2-6alkenyl or C2-6alkynyl; R4 and R5 are hydroxy; halo; C3-7cycloalkyl; C1-6alkyloxy; carboxyl; C1-6alkyloxycarbonyl; formyl; cyano; nitro; amino; mono- or di(C1-6alkyl)amino; polyhaloC1-6alkyl; polyhaloC1-6alkyloxy; —C(═O)R9; cyano; —S(═O)rR9; —NH—S(═O)2R9; —NHC(═O)H; —C(═O)NHNH2; —NHC(═O)R9; Het; —Y-Het; optionally substituted C1-6alkyl, C2-6alkenyl or C2-6alkynyl; R5 is pyridyl, —C(═O)NR5aR5b; —CH(OR5c)R5d; —CH2—NR5eR5f; —CH═NOR5a; —CH2—O—C2-6alkenyl; —CH2—O—P(═O)(OR5g)2; —CH2—O—C(═O)—NH2; —C(═O)—R5d; X is —NR1—, —O—, —CH2—, —S—; pharmaceutical compositions containing these compounds as active ingredient and processes for preparing said compounds and compositions.
US09006241B2 Pyrimidine derivatives
The invention provides novel pyrimidine derivatives of formula (I), methods of preparing such compounds, pharmaceutical compositions containing such compounds, and methods for using such compounds in treatment of diseases including cancer; wherein R1-R11, Z, and Y are as defined in the specification.
US09006240B2 Method for assay on the effect of vascularization inhibitor
The present invention provides a method of predicting the antitumor effect of an angiogenesis inhibitor. It is possible to predict the antitumor effect of an angiogenesis inhibitor by evaluating the EGF dependency of a tumor cell for proliferation and/or survival and using the EGF dependency as an indicator. Since the antitumor effect of an angiogenesis inhibitor correlates with the EGF dependency of a tumor cell for proliferation and/or survival, the angiogenesis inhibitors is capable of producing excellent antitumor effect when combined with a substance having EGF inhibitory activity.
US09006239B2 2-aryl-4-quinazolinones and their pharmaceutical compositions
Provided is a compound of the formula I or a pharmaceutically acceptable salt, solvate or stereoisomer thereof: wherein Ar represents R5, R7, R8, R2′, R4′, R5′, R6′, R7′, R8′ independently represent H, OH, F, Cl, Br, methoxyl group, NH2 group or NMe2 group; X represents NH, O or S; and R6 is selected from the group consisting of: pyrrolidinyl group, piperidinyl group, morpholino group, methoxyl group, and dimethylamine group. The present invention also provides a composition comprising the compound of formula I. The compound and the composition in accordance with the present invention are effective on treating or alleviating a disease or disorder, such as malignant glioma.
US09006238B2 Pyrazolo pyridine derivatives as NADPH oxidase inhibitors
The present invention is related to pyrazolo pyridine derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
US09006232B2 Pyrimidone derivatives
A compound represented by the formula (I) or a pharmaceutically acceptable salt thereof: wherein Z represents nitrogen atom or C—X; X represents hydrogen atom or fluorine atom; R1 is hydrogen atom or a C1-C3 alkyl group; L represents single bond or a C1-C6 alkylene group which may be substituted; Y represents single bond, sulfur atom, oxygen atom, NH, or the like; R2 represents hydrogen atom or a cyclic group which may be substituted, which is used for preventive and/or therapeutic treatment of a disease caused by abnormal activity of tau protein kinase 1 such as a neurodegenerative diseases (e.g. Alzheimer disease).
US09006221B2 Method of modulating ship activity
A method of treating or preventing an immune disorder, such as graft versus host disease, in a subject. The method includes the administering a SHIP1 inhibitor, such as 3α-aminocholestane, to a subject in need of treatment. Thus, SHIP1 inhibitors taught herein represent a novel class of small molecules that have the potential to enhance allogeneic transplantation, boost innate immunity and improve the treatment of hematologic malignancies.
US09006220B2 23-yne-vitamin D3 derivative
To provide a novel vitamin D3 derivative useful as a therapeutic agent for osteoporosis.Provided is a vitamin D3 derivative represented by the following formula (1) or a medicinally acceptable solvate thereof: wherein R1 represents a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, an alkylcarbonyloxyalkyl group with each alkyl having 1 to 6 carbon atoms, or an arylcarbonyloxyalkyl group with the aryl having 6 to 10 carbon atoms and the alkyl having 1 to 6 carbon atoms; R2 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms or, together with the other R2 and the carbon atom to which they are bound to, may form a cyclic alkyl group having 3 to 6 carbon atoms; R3 represents an alkyl group having 1 to 6 carbon atoms or, together with the other R3 and the carbon atom to which they are bound to, may form a cyclic alkyl group having 3 to 6 carbon atoms; X represents an oxygen atom or a methylene group; and n represents an integer of 1 or 2.
US09006209B2 Uracyl spirooxetane nucleoside phosphoramidates
This invention relates to a stereochemically pure uracyl spirooxetane nucleoside phosphoramidate which inhibits the hepatitis C virus (HCV).
US09006208B2 Agent for treatment of dry eye characterized by combining P2Y2 receptor agonist and hyaluronic acid or salt thereof, method for treating dry eye, and use of the P2Y2 receptor agonist and hyaluronic acid or salt thereof
An agent for treatment of dry eye comprising a combination of a P2Y2 receptor agonist at a therapeutically effective concentration and hyaluronic acid or a salt thereof at a therapeutically effective concentration, which agent has a dosage form of an ophthalmic agent, can promote the secretion of tear remarkably and can improve corneal epithelial disorders remarkably, and is therefore expected to be a novel agent for treatment of dry eye.
US09006207B2 Compositions useful for treating disorders related to TRPA1
Compounds and compositions for treating disorders related to TRPA1 are described herein.
US09006206B2 Composition and methods for modulating cell proliferation and cell death
Described herein are compositions and methods for modulation of p53-dependent cell death and cell proliferation. The compositions are microRNAs and associated nucleic acids.
US09006205B2 Antisense oligonucleotides against neutral sphingomyelinase and neutral sphingomyelinase inhibitor GW4869 for degenerative neurological disorders
Alzheimer's disease (AD) is the most common human neurodegenerative disease of the CNS resulting in progressive neuronal death and memory loss. Despite intense investigations, no effective therapy is available to stop its onset or halt its progression. It was discovered that antisense oligonucleotide against neutral sphingomyelinase and GW4869, a chemical inhibitor of neutral sphingomyelinase, inhibit activation of glial cells and protect neurons in AD cell culture and animal models. These results suggest the following new treatment options for AD patients: Antisense oligonucleotide against neutral sphingomyelinase and GW4869.
US09006204B2 Aptamers for prion diagnostics and aptamer binding detection system
There is disclosed PrPSc aptamers. There is further disclosed PrPSc aptamers. There is further disclosed an infectious agent or neurodegenerative disease bifunctional aptamer comprising a first sequence component, and a second sequence component, wherein the first sequence component is a complement binding sequence component selected from the group consisting of SEQ ID NOs 1-89 and 92-96, each having a 5′ end and a 3′ end, wherein the second sequence component binds to a specific infectious agent, and wherein the second sequence component sequence is inserted into the first sequence component from 1 to 5 bases from the 5′ end.
US09006202B2 Method and compositions for treating HIV infection
A method for treating latent HIV infection is disclosed. The method includes administering to a subject in need of such treatment an effective amount of an anti-IκBα agent, an anti-IκBε agent or both; and administering to the subject an effective amount of an antiviral agent. A pharmaceutical composition for treating latent HIV infection is also disclosed.
US09006195B2 Regulation of hematopoietic stem cell functions through microRNAs
The present disclosure relates to regulation of functions of hematopoietic stem cells (HSCs) by delivering of miRNAs, including miR-125b, miR-126, and miR-155, to HSCs. For example, in some embodiments, blood output in a mammal can be increased by administering miR-125b, miR-126, and/or miR-155 oligonucleotides. Also disclosed are methods for promoting hematopoietic stem cell engraftment and method for treating a myeloproliferative disorder.
US09006189B2 Triazole compounds and methods of making and using the same
The present invention provides triazole macrocyclic compounds useful as therapeutic agents. More particularly, these compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents.
US09006188B2 Co-crystals of dapagliflozin
The present invention provides novel co-crystal forms of dapagliflozin, namely a dapagliflozin lactose co-crystal and a dapagliflozin asparagine co-crystal, to pharmaceutical compositions comprising same, methods for their preparation and uses thereof for treating type 2 diabetes.
US09006187B2 Thiophene derivative as SGLT2 inhibitor and pharmaceutical composition comprising same
The present invention relates to a novel compound with thiophene ring having an inhibitory activity against sodium-dependent glucose cotransporter 2 (SGLT2) being present in the intestine and kidney, and a pharmaceutical composition comprising the same as an active ingredient, which is useful for preventing or treating metabolic disorders, particularly diabetes. The prevention also provides a method for preparing same, a pharmaceutical composition containing same, and a method for preventing or treating metabolic disorders, particularly diabetes.
US09006185B2 Use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of various diseases
The present invention refers to the use of protein kinase inhibitors and more specifically to the use of inhibitors of the protein kinase c-Jun amino terminal kinase, JNK inhibitor sequences, chimeric peptides, or of nucleic acids encoding same as well as pharmaceutical compositions containing same, for the treatment of various diseases or disorders strongly related to JNK signaling, wherein these diseases or disorders are selected from autoimmune disorders, cardiovascular diseases, cancerous diseases, diabetes, including diabetes type 1 or type 2, inflammatory diseases, hair loss, including Alopecia areata, diseases of the lung, neuronal or neurodegenerative diseases, diseases of the liver, diseases of the spine, diseases of the uterus, viral infectious diseases and depressive disorders.
US09006184B2 Cancer vaccine composition
A cancer vaccine composition for human leukocyte antigen (HLA)-A*0206-positive persons, comprising a protein product of the tumor suppressor gene WT1 or a partial peptide thereof.
US09006182B2 Light activated composite tissue adhesives
A light activated collagen-flavin composite layer incorporating riboflavin is applied as treatment for infected lesions. These composites have also been found to be strong tissue adheives that are effective in closing and sealing wounds, fixation of grafts/ implants and anastomoses. Advantages include speed of closure, reduced infection due to the elimination of foreign matter, evidence of accelerated wound healing and the ease of use in complex surgery, especially when watertight seals, limited access or small repair size are important factors. The riboflavin in the collagen layer is exposed to light (e.g., light having a wavelength between 360-375 nm or 440-480 nm), decomposing the riboflavin to form reactive oxygen species (ROS). Strong crosslinks between the collagen composite and tissue results. In addition, similar exposures eradicate pathogens in the wound.
US09006178B2 Double-acylated GLP-1 derivatives with a linker
The invention relates to a derivative of a GLP-1 analog, which analog comprises a first K residue at a position corresponding to position 18 of GLP-1(7-37) (SEQ ID NO: 1), a second K residue at another position, and a maximum of twelve amino acid changes as compared to GLP-1(7-37); which derivative comprises two protracting moieties attached to said first and second K residue, respectively, via a linker, wherein the protracting moiety is selected from Chem. 1: HOOC—(CH2)x—CO—*, and Chem. 2: HOOC—C6H4-0-(CH2)y—CO—*, in which x is an integer in the range of 6-18, and y is an integer in the range of 3-17; and the linker comprises Chem. 3: *—NH—(CH2)q—CH[(CH2)w—NH2]—CO—*, wherein q is an integer in the range of 0-5, and w is an integer in the range of 0-5; or a pharmaceutically acceptable salt, amide, or ester thereof. The invention also relates to the pharmaceutical use thereof, for example in the treatment and/or prevention of all forms of diabetes and related diseases, as well as to corresponding novel peptides and side chain intermediates. The derivatives are potent, protracted, and suitable for oral administration.
US09006172B2 Peptide analogs for treating diseases and disorders
A peptide having a sequence selected from SEQ ID NO:11, SEQ ID NO:12, SEQ ID NO:13, SEQ ID NO:14, SEQ ID NO:15, SEQ ID NO:16, SEQ ID NO:17 and SEQ ID NO:18. Said peptide used for the treatment of type I diabetes, Type II diabetes, metabolic syndrome, or obesity, or of apetite suppression, or for mitigating insulin resistance, or for reducing an undesirably high fasting serum glucose level, or for reducing an undesirably high peak serum glucose level, or for reducing an undesirably high peak serum insulin level, or for reducing an undesirably large response to a glucose tolerance test.
US09006167B2 Cleaning composition
Provided is an aqueous cleaning composition comprising at least one surfactant, xanthan gum, and a carbonate salt, wherein the composition has a turbidity of less than 16 NTU. Also provided is a method of cleaning a substrate by applying the cleaning composition to the substrate.
US09006165B2 Low-VOC cleaning substrates and compositions comprising a cationic biocide and glycol ether solvent
A cleaning composition for sanitizing and/or disinfecting hard surfaces, comprising:a cationic biocide, surfactant and low levels of VOC solvents. The cleaning composition is adapted to clean a variety of hard surfaces without leaving behind a visible residue and creates low levels of streaking and filming on the treated surface. The cleaning composition contains less than 5% by weight of VOCs. The cleaning composition may be used alone as a liquid or spray formulation or in combination with a substrate, for example, a pre-loaded cleaning wipe.
US09006164B2 Resist remover composition and method for removing resist using the composition
The present invention is directed to provide a resist remover composition for semiconductor substrate which enables to remove a resist simply and easily in the photolithography process in the semiconductor field, and a method for removing a resist comprising that the composition is used. The present invention relates to a resist remover composition for semiconductor substrate, comprising [I] a carbon radical generating agent, [II] an acid, [III] a reducing agent, and [IV] an organic solvent, and having pH of lower than 7, and a method for removing a resist, comprising that the composition is used.
US09006160B2 Lubricating oil compositions containing epoxide antiwear agents
A lubricating oil composition comprising (a) a major amount of an oil of lubricating viscosity; and (b) an oil soluble epoxide compound having the following structure: wherein X is hydrogen or a substituted or unsubstituted C1 to C20 hydrocarbyl group, wherein the substituted hydrocarbyl group is substituted with one or more substituents selected from hydroxyl, alkoxy, ester or amino groups and Y is —CH2OR, —C(═O)OR1 or —C(═O)NHR2, wherein R, R1 and R2 are independently hydrogen or C1 to C20 alkyl or alkenyl groups; and further wherein the oil of lubricating viscosity does not contain a carboxylic acid ester.
US09006159B2 Star polymer lubricating composition
The invention provides a lubricating composition containing (a) 0.001 wt % to 15 wt % of a polymer with radial or star architecture; (b) an overbased detergent; (c) a dispersant; and (d) an oil of lubricating viscosity. The invention further provides a method for lubricating a mechanical device with the lubricating composition.
US09006157B2 Silicone wax emulsion and method of manufacture
Disclosed herein are silicone wax emulsions and methods of manufacturing the same. One method of manufacturing silicone wax emulsions as disclosed herein comprises charging alpha-olefins of C-18 or greater chain length to a heating and mixing vessel along with undecylenic acid and blocking the carboxylic acid of the undecylenic acid with a compound containing a trimethylsilyl group by adding the compound in sufficient quantity and heating as a melt until blocking is complete. While maintaining a melt temperature, a silicone polymer containing methyl hydrogen siloxy units is added, followed by a hydrosilation reaction catalyst to effect a hydrosilation reaction. This results in an acid functional silicone polymer. The acid functional silicone polymer is combined with an emulsifier, and the molten combination is added to a stirred solution of alkaline agent and water that has been heated to a temperature above the silicone wax melting point. This process produces silicone wax emulsions with excellent qualities.
US09006154B2 Methods for determining reactive index for cement kiln dust, associated compositions and methods of use
A variety of methods and compositions are disclosed, including, in one embodiment, a method of treating a well comprising: providing a treatment fluid comprising a base fluid and a blended cementitious component, wherein the blended cementitious component comprises kiln dust from two or more different sources; and introducing the treatment fluid into a well bore.
US09006152B2 Cement compositions and associated methods comprising sub-micron calcium carbonate and latex
Methods and compositions are provided that relate to cement compositions comprising sub-micron calcium carbonate and latex. An embodiment includes a cement composition comprising: cement, water, sub-micron calcium carbonate having a particle size in a range of from greater than 100 nanometers to about 1 micron, and latex.
US09006146B2 Superconducting cable
An AC superconducting cable with an insulating layer on the external circumference of a conductor, and wherein: the insulating layer includes a first insulating layer, a second insulating layer and a third insulating layer, from the inside layer to the outside layer; the insulating layer is impregnated with liquid nitrogen; the product of the dielectric constant ∈1 of the first insulating layer and the dielectric loss tangent tan δ1 and the product of the dielectric constant ∈2 of the second insulating layer and the dielectric loss tangent tan δ2 fulfilling the relationship ∈1×tan δ1>∈2×tan δ2; and the product of the dielectric constant ∈2 of the second insulating layer and the dielectric loss tangent tan δ2 and the product of the dielectric constant ∈3 of the third insulating layer and the dielectric loss tangent tan δ3 fulfilling the relationship ∈2×tan δ2<∈3×tan δ3.
US09006145B2 Agrochemical formulations of microcapsules for compounds containing carboxamide groups
The present invention is directed towards microcapsules, uses and methods of microencapsulation with improved properties regarding agglomeration, bleeding and control of the reaction. The invention is especially suitable for chemical compounds with at least one carboxamide group, preferably for microencapsulation of those compounds wherein the carbonyl group is attached to a nitrogen atom or nitrogenated heterocycle and wherein the microencapsulation reaction may be too vigorous. The microcapsules are characterized by a mixed glycoluril-polyurea polymer wall, wherein the polyurea groups come from a urea-formaldehyde resin and not from isocyanate monomers or prepolymers. The process of making such microcapsules a dispersant in the oil phase of the type of block copolymer of vinylpyrrolidone/vinylalkene and/or vinylpyrrolidone/vinyl acetate and the microencapsulation reaction may be carried out without the presence of any polyamine/polyol acting as a catalyst.
US09006134B2 Particulate water absorbing agent and manufacturing method of same
The application relates to the particulate water absorbing agent of the present invention composed primarily of a polyacrylic acid- or polyacrylate-based water absorbing resin and containing a chelating agent and a phosphorous compound. Accordingly, the particulate water absorbing agent composed primarily of a water absorbing resin achieves both excellent water absorbing properties and anti-coloring effect which would normally be incompatible. A particulate water absorbing agent for absorbent core is provided that is suitable for actual use.
US09006131B2 Composite oxide for exhaust gas purification catalyst, method for manufacturing the same, coating material for exhaust gas purification catalyst, and filter for diesel exhaust gas purification
A composite oxide for an exhaust gas purification catalyst is provided which can burn PM in diesel engine exhaust gas at low temperatures and has a good S desorption property. The composite oxide for an exhaust gas purification catalyst is composed of Ce, Bi, Pr, R, and oxygen in a molar ratio of Ce:Bi:Pr:R=(1−x−y−z):x:y:z. The ratios of Ce, Bi, Pr, and R satisfy 0
US09006130B2 Alumina nanotube/nanorod supported hydrodesulfurization nanocatalyst, method of preparation and application
The invention relates to a hydrodesulfurization nanocatalyst, use of the hydrodesulfurization nanocatalyst in a hydrodesulfurization process and a process for producing the hydrodesulfurization nanocatalyst. The hydrodesulfurization nanocatalyst can include a nanostructured alumina material, at least one metal selected from group VI B of the periodic table of elements, and at least one metal selected from group VIII B of the periodic table of elements.
US09006127B2 Support for silver catalyst in ethylene oxide production, methods for preparing the same, silver catalyst prepared therefrom, and use thereof
The present invention relates to a support for silver catalyst used in the ethylene oxide production, a preparation method for the same, a silver catalyst prepared from the same, and its use in the ethylene oxide production. The silver catalyst produced from the silver catalyst support has an improved activity, stability and/or selectivity in the production of ethylene oxide by epoxidation of ethylene.
US09006121B2 Construction articles and methods of forming same
A pipe choke for use in drilling and mining operations comprising a body including a first end and a second end configured to couple to a pipe, an opening extending through the body from the first end to the second end, and wherein the body includes a first phase comprising recrystallized silicon carbide and a second phase comprising silicon.
US09006118B2 Flame resistant filler cloth and mattresses incorporating same
A filler cloth includes cellulosic fibers treated with a flame retardant chemistry such that the filler cloth has a char length of less than about nine inches when tested in accordance with NFPA 701, such that thermal shrinkage of the filler cloth at 400° F. is less than about 35% in any direction, and such that the filler cloth maintains flame and heat resistant integrity when impinged with a gas flame in accordance with testing protocols set forth in Technical Bulletin 603 of the State of California Department of Consumer Affairs. The filler cloth cellulosic fibers are treated with a flame retardant chemistry such that the filler cloth has a Frazier air permeability of less than about 400 cfm and a thermal resistance rating of at least about 3 when tested according to NFPA 2112.
US09006114B2 Method for selectively removing a spacer in a dual stress liner approach
By integrating a spacer removal process into the sequence for patterning a first stress-inducing material during a dual stress liner approach, the sidewall spacer structure for one type of transistor may be maintained, without requiring additional lithography steps.
US09006111B2 Pattern forming method
A pattern-formation process including: providing a substrate material having on a major surface a difficult-to-access recess formed by a 1st mask; depositing a 2nd mask having a higher etching resistance than the 1st mask by physical evaporation on the upper surface of the 1st mask and peripherally on a side of the recess, the second mask forming a series of films; and etching the substrate material via the 1st and 2nd mask, wherein forming the 2nd mask includes depositing the 2nd mask material by physical evaporation vertically onto the major surface of the substrate material; and the recess is sized such that, upon deposition, the 2nd mask material cannot substantially reach the bottom of the recess. Accordingly, portions of the recesses formed by the etching masks can be processed by etching even when those recesses are 25 nm or less, and especially 20 nm or less in size.
US09006110B1 Method for fabricating patterned structure of semiconductor device
A method for fabricating a patterned structure of a semiconductor device includes: forming first mandrels and second mandrels on a substrate, wherein a first spacing is defined between the two adjacent first mandrels and a second spacing is defined between the two adjacent second mandrels, the first spacing being wider than the second spacing; forming a cover layer to cover the first mandrels while exposing the second mandrels; etching the cover layer and the second mandrels; removing the cover layer; concurrently forming first spacers on the sides of the first mandrels and a second spacers on the sides of the second mandrels after removing the cover layer; and transferring a layout of the first and second spacers to the substrate so as to form fin-shaped structures.
US09006107B2 Patterned structure of semiconductor device and fabricating method thereof
A method for fabricating a patterned structure in a semiconductor device is provided. First, a substrate with a first region and a second region is provided. Then, a plurality of sacrificial patterns is respectively formed within the first region and the second region. A first spacer is then formed on the sidewalls of each of the sacrificial patterns followed by forming a mask layer to cover the sacrificial patterns located within the first region. Finally, the first spacer exposed from the mask layer is trimmed to be a second spacer and the mask layer is then removed.
US09006105B2 Method of patterning platinum layer
A method of patterning a platinum layer includes the following steps. A substrate is provided. A platinum layer is formed on the substrate. An etching process is performed to pattern the platinum layer, wherein an etchant used in the etching process simultaneously includes at least a chloride-containing gas and at least a fluoride-containing gas.
US09006102B2 Hybrid TSV and method for forming the same
Generally, the subject matter disclosed herein relates to conductive via elements, such as through-silicon vias (TSV's), and methods for forming the same. One illustrative method of forming a conductive via element disclosed herein includes forming a via opening in a substrate, the via opening extending through an interlayer dielectric layer formed above the substrate and a device layer formed below the interlayer dielectric layer, and extending into the substrate. The method also includes forming a first portion of the conductive via element comprising a first conductive contact material in a bottom portion of the via opening, and forming a second portion of the conductive via element comprising a second conductive contact material different from the first conductive contact material in an upper portion of the via opening and above the first portion.
US09006099B2 Semiconductor device and method of forming a power MOSFET with interconnect structure silicide layer and low profile bump
A semiconductor device has a substrate with a source region and a drain region formed on the substrate. A silicide layer is disposed over the source region and drain region. A first interconnect layer is formed over the silicide layer and includes a first runner connected to the source region and second runner connected to the drain region. A second interconnect layer is formed over the first interconnect layer and includes a third runner connected to the first runner and a fourth runner connected to the second runner. An under bump metallization (UBM) is formed over and electrically connected to the second interconnect layer. A mask is disposed over the substrate with an opening in the mask aligned over the UBM. A conductive bump material is deposited within the opening in the mask. The mask is removed and the conductive bump material is reflowed to form a bump.
US09006097B2 Cu pillar bump with electrolytic metal sidewall protection
A method of forming a bump structure includes providing a semiconductor substrate and forming an under-bump-metallurgy (UBM) layer on the semiconductor substrate. The method further includes forming a mask layer on the UBM layer, wherein the mask layer has an opening exposing a portion of the UBM layer. The method further includes forming a copper layer in the opening of the mask layer and removing a portion of the mask layer to form a space between the copper layer and the mask layer. The method further includes performing an electrolytic process to fill the space with a metal layer and removing the mask layer.
US09006096B1 Processes and structures for IC fabrication
The present invention discloses methods and apparatuses for the separations of IC fabrication and assembling of separated IC components to form complete IC structures. In an embodiment, the present fabrication separation of an IC structure into multiple discrete components can take advantages of dedicated IC fabrication facilities and achieve more cost effective products. In another embodiment, the present chip assembling provides high density interconnect wires between bond pads, enabling cost-effective assembling of small chip components. In an aspect, the present process coats the component surfaces to facilitate the bonding of the bond pads. In another aspect, the present process coats the bond pads with shelled capsules to facilitate the bonding of the bond pads.
US09006095B2 Semiconductor devices and methods of manufacture thereof
Semiconductor devices and methods of manufacture thereof are disclosed. In one embodiment, a method of manufacturing a semiconductor device includes providing a workpiece including a conductive feature formed in a first insulating material and a second insulating material disposed over the first insulating material. The second insulating material has an opening over the conductive feature. The method includes forming a graphene-based conductive layer over an exposed top surface of the conductive feature within the opening in the second conductive material, and forming a carbon-based adhesive layer over sidewalls of the opening in the second insulating material. A carbon nano-tube (CNT) is formed in the patterned second insulating material over the graphene-based conductive layer and the carbon-based adhesive layer.
US09006089B2 Nonvolatile memory device and method for fabricating the same
The technology of the present invention relates to a non-volatile memory device and a fabrication method thereof. The non-volatile memory device includes channel layers protruding vertically from a substrate, a plurality of hole-supply layers and a plurality of gate electrodes, which are alternately stacked along the channel layers, and a memory film interposed between the channel layers and the gate electrodes and between the hole-supply layers and the gate electrodes. According to this technology, the hole-supply layers are formed between the memory cells such that sufficient holes are supplied to the memory cells during the erase operation of the memory cells, whereby the erase operation of the memory cells is smoothly performed without using the GIDL current, and the properties of the device are protected from being deteriorated due to program/erase cycling.
US09006088B2 Method for forming semiconductor gate structure and semiconductor gate structure
A method for forming a semiconductor gate structure and a semiconductor gate structure are provided. The method includes: providing a substrate with a Ge layer as a surface thereof; forming a Sn layer on the Ge layer, in which an interface between the Ge layer and the Sn layer is a GeSn layer; removing the Sn layer to expose the GeSn layer; forming a GeSnOx passivation layer by performing an oxidation treatment for the GeSn layer, or forming a GeSnN or GeSnON passivation layer by performing a passivation treatment for the GeSn layer; and forming a gate stack on the GeSnOx , GeSnN or GeSnON passivation layer.
US09006083B1 Epitaxially growing GaN layers on silicon (100) wafers
Methods and structures for GaN on silicon-containing substrates are disclosed, comprising a texturing process to generate a rough surface containing (111) surface, which then can act as an underlayer for epitaxial GaN. LED devices are then fabricated on the GaN layer. Variations of the present invention include different orientations of silicon layer instead of (100), such as (110) or others; and other semiconductor materials instead of GaN, such as other semiconductor materials suitable for LED devices.
US09006077B2 Gate length independent silicon-on-nothing (SON) scheme for bulk FinFETs
Methods for fabricating integrated circuits and FinFET transistors on bulk substrates with active channel regions isolated from the substrate with an insulator are provided. In accordance with an exemplary embodiment, a method for fabricating an integrated circuit includes forming fin structures overlying a semiconductor substrate, wherein each fin structure includes a channel material and extends in a longitudinal direction from a first end to a second end. The method deposits an anchoring material over the fin structures. The method includes recessing the anchoring material to form trenches adjacent the fin structures, wherein the anchoring material remains in contact with the first end and the second end of each fin structure. Further, the method forms a void between the semiconductor substrate and the channel material of each fin structure with a gate length independent etching process, wherein the channel material of each fin structure is suspended over the semiconductor substrate.
US09006075B2 Memory cells, semiconductor devices including such cells, and methods of fabrication
Memory cells are disclosed, which cells include a cell material and an ion-source material over the cell material. A discontinuous interfacial material is included between the cell material and the ion-source material. Also disclosed are fabrication methods and semiconductor devices including the disclosed memory cells.
US09006074B2 High voltage hybrid polymeric-ceramic dielectric capacitor
An integrated circuit includes isolation capacitors which include a silicon dioxide dielectric layer and a polymer dielectric layer over the layer of silicon dioxide. The silicon dioxide dielectric layer and the polymer dielectric layer extend across the integrated circuit. Top plates of the isolation capacitors have bond pads for wire bonds or bump bonds. Bottom plates of the isolation capacitors are connected to components of the integrated circuit. Other bond pads are connected to components in the integrated circuit through vias through the silicon dioxide dielectric layer and the polymer dielectric layer.
US09006071B2 Thin channel MOSFET with silicide local interconnect
A semiconductor structure and method of manufacturing the same are provided. The semiconductor structure includes a semiconductor substrate having an isolated area comprising a first region and a second region. A first raised RSD region is formed in the first region and a second RSD region is formed in the second region. The first RSD region and second RSD region is separated laterally by a portion of the isolated area. A continuous silicide interconnect structure is formed overlying the first RSD region, the second RSD region and the portion of the isolated area situated between RSD regions. A contact may be formed on the surface of the silicide interconnect.
US09006063B2 Trench MOSFET
A method for forming a trench MOSFET includes doping a body region of the trench MOSFET in multiple ion implantation steps each having different ion implantation energy. The method further comprises etching the trench to a depth of about 1.7 μm.
US09006061B2 Vertical metal insulator metal capacitor
A method of forming a capacitor comprises forming a first electrode of the capacitor over a substrate. The first electrode includes a bottom conductive plane and a plurality of first vertical conductive structures on the bottom conductive plane. The method also comprises forming an insulating structure over the first electrode. The method further comprises forming a second electrode of the capacitor over the insulating structure. The second electrode includes a top conductive plane and a plurality of second vertical conductive structures under the top conductive plane. The first vertical conductive structures of the plurality of first vertical conductive structures and the second vertical conductive structures of the plurality of second vertical conductive structures are interlaced with each other.
US09006059B2 CMOS transistor and method for fabricating the same
The invention provides a method for fabricating a CMOS transistor and a method for fabricating an array substrate. The method for fabricating a CMOS transistor comprises a step of forming channels, which comprises: depositing an amorphous silicon layer on a substrate, and crystallizing the amorphous silicon layer into a poly-silicon layer; implanting boron atoms into the poly-silicon layer and then forming an N channel region and a P channel region by etching the poly-silicon layer implanted with the boron atoms; forming a photoresist-partially-retained region corresponding to the N channel region and a photoresist-completely-retained region corresponding to the P channel region through a single patterning process; and removing the photoresist in the photoresist-partially-retained-region and retaining a part of the photoresist in the photoresist-completely-retained region using an ashing process, implanting phosphorus atoms through ion implantation thereby forming an N channel and a P channel.
US09006054B2 Lateral diode compatible with FinFET and method to fabricate same
A method to fabricate a diode device includes providing a fin structure formed in a SOI layer. The fin structure has a sacrificial gate structure disposed on the fin structure between a first end of the fin structure and a second end of the fin structure. The method further includes depositing first doped semiconductor material on the first and second ends of the fin structure, where the first doped semiconductor material on the first end of the fin structure has one of the same doping polarity or an opposite doping polarity as the first doped semiconductor material on the second end of the fin structure. The method further includes removing the sacrificial gate structure to form a gap between the deposited first doped semiconductor material; depositing a second doped semiconductor material within the gap and forming first and second electrical contacts conductively connected to the first doped semiconductor material.
US09006044B2 Graphene device and method of manufacturing the same
A method of manufacturing a graphene device may include forming a device portion including a graphene layer on the first substrate; attaching a second substrate on the device portion of the first substrate; and removing the first substrate. The removing of the first substrate may include etching a sacrificial layer between the first substrate and the graphene layer. After removing the first substrate, a third substrate may be attached on the device portion. After attaching the third substrate, the second substrate may be removed.
US09006043B2 Manufacturing method of semiconductor device
The invention provides a technique to manufacture a highly reliable semiconductor device and a display device at high yield. As an exposure mask, an exposure mask provided with a diffraction grating pattern or an auxiliary pattern formed of a semi-transmissive film with a light intensity reducing function is used. With such an exposure mask, various light exposures can be more accurately controlled, which enables a resist to be processed into a more accurate shape. Therefore, when such a mask layer is used, the conductive film and the insulating film can be processed in the same step into different shapes in accordance with desired performances. As a result, thin film transistors with different characteristics, wires in different sizes and shapes, and the like can be manufactured without increasing the number of steps.
US09006041B2 Bipolar punch-through semiconductor device and method for manufacturing such a semiconductor device
A method for manufacturing a bipolar punch-through semiconductor device is disclosed, which includes providing a wafer having a first and a second side, wherein on the first side a high-doped layer of the first conductivity type having constant high doping concentration is arranged; epitaxially growing a low-doped layer of the first conductivity type on the first side; performing a diffusion step by which a diffused inter-space region is created at the inter-space of the layers; creating at least one layer of the second conductivity type on the first side; and reducing the wafer thickness within the high-doped layer on the second side so that a buffer layer is created, which can include the inter-space region and the remaining part of the high-doped layer, wherein the doping profile of the buffer layer decreases steadily from the doping concentration of the high-doped region to the doping concentration of the drift layer.
US09006040B2 Systems and methods for fabricating semiconductor devices having larger die dimensions
A method of fabricating a semiconductor device is disclosed. A photosensitive material is coated over the device. A plurality of masks for a chip layout are obtained. The plurality of masks are exposed to encompass a chip area of the device using at least one reticle repeatedly. The at least one reticle is of a set of reticles. The chip area has a resultant dimension greater than a dimension of the at least one reticle. A developer is used to remove soluble portions of the photosensitive material forming a resist pattern in the chip area.
US09006035B2 Method for manufacturing package structure with electronic component
A fabrication method of manufacturing a package a plurality of electronic components in an encapsulation body, firstly, mounting the plurality of electronic components and one ends of a plurality of metal resilient units on a substrate. After that, the plurality of electronic components and the plurality of metal resilient units are encapsulated on the substrate to form an encapsulation body with another ends of the plurality of metal resilient units exposed on an exterior surface of the encapsulation body. Then etching remaining epoxy resin on the other ends of the plurality of metal resilient units.
US09006033B2 Method of making package with interposer frame
A method of forming a package on package structure includes bonding a semiconductor die and an interposer frame to a substrate, and the interposer frame surrounds the semiconductor die. The semiconductor die is disposed in an opening of the interposer frame, and the interposer frame has a plurality of TSHs. The plurality of TSHs is aligned with a plurality of bumps on the substrate. The method also includes positioning a packaged die over the semiconductor die and the interposer frame. The packaged die has a plurality of bumps aligned with the plurality of TSHs of the interposer. The method further includes performing a reflow process to allow solder of the plurality of bumps of the substrate and the solder of the plurality of bumps of the packaged die to fill the plurality of TSHs.
US09006030B1 Warpage management for fan-out mold packaged integrated circuit
An integrated circuit includes a stacked conductive layer interposer and a first die at least partially encapsulated in a mold material. The first die is mechanically and electrically attached to a top surface of the stacked conductive layer interposer using solder bumps. The integrated circuit further includes a first warpage correction layer.
US09006022B2 Method for fabricating phase change memory
A method is provided for fabricating a phase change memory. The method includes providing a semiconductor substrate having a bottom electrode connecting with one or more semiconductor devices, and forming a first dielectric layer on the semiconductor substrate. The method also includes forming a loop-shape electrode in the first dielectric layer, and forming a second dielectric layer having a first opening exposing a portion of the first dielectric layer and a portion of the loop-shape electrode. Further, the method includes forming a phase change layer in the first opening of the second dielectric layer such that a contact area between the phase change layer and the loop-shape electrode may be controlled to achieve desired contact, and forming a top electrode.
US09006018B2 Method of manufacturing a solid-state imaging device
A solid-state imaging device including a substrate; a wiring layer formed on a front side of the substrate in which pixels are formed; a surface electrode pad section formed in the wiring layer; a light-shielding film formed on a rear side of the substrate; a pad section base layer formed in the same layer as the light-shielding film; an on-chip lens layer formed over the light-shielding film and the pad section base layer in a side opposite from the substrate side; a back electrode pad section formed above the on-chip lens layer; a through-hole formed to penetrate the on-chip lens layer, the pad section base layer, and the substrate so as to expose the surface electrode pad section; and a through-electrode layer which is formed in the through-hole and connects the surface electrode pad section and the back electrode pad section.
US09006017B2 Photoelectric conversion device and method for manufacturing the same
A circuit layer is formed on a surface of a substrate and includes a transistor. A photoelectric conversion element includes a photoelectric conversion layer of a chalcopyrite-type semiconductor provided between a first electrode and a second electrode. A supply layer is formed between the circuit layer and the photoelectric conversion layer and contains an Ia group element. Diffusion of the Ia group element to the photoelectric conversion layer improves the photoelectric conversion efficiency. A protective layer is formed between the supply layer and the circuit layer and prevents the diffusion of the Ia group element to the circuit layer.
US09006014B2 Fabrication of three-dimensional high surface area electrodes
A method for fabricating three dimensional high surface electrodes is described. The methods including the steps: designing the pillars; selecting a material for the formation of the pillars; patterning the material; transferring the pattern to form the pillars; insulating the pillars and providing a metal layer for increased conductivity. Alternative methods for fabrication of the electrodes and fabrication of the electrodes using CMOS are also described.
US09006012B2 Organic light emitting diode display and method of manufacturing the same
A method of manufacturing an organic light emitting diode display according to an exemplary embodiment of the present invention includes: forming a first electrode on a substrate; forming an insulation layer on the first electrode; etching the insulation layer to expose the first electrode so as to form a pixel defining layer having the same height as the first electrode; forming an organic layer including one or more emission layers on the first electrode of a sub-pixel region defined by the pixel defining layer by applying a laser-induced thermal imaging (LITI) method; and forming a second electrode on the organic layer.
US09006009B2 Organic light emitting diode display device and method of fabricating the same
In an organic light emitting diode (OLED) display device and a method for fabricating the same, OLED pixels are patterned through a photolithography process, so a large area patterning can be performed and a fine pitch can be obtained, and an organic compound layer can be protected by forming a buffer layer of a metal oxide on an upper portion of the organic compound layer or patterning the organic compound layer by using a cathode as a mask, improving device efficiency. In addition, among red, green, and blue pixels, two pixels are patterned through a lift-off process and the other remaining one is deposited to be formed without patterning, the process can be simplified and efficiency can be increased.
US09006005B2 Flip light emitting diode chip and method of fabricating the same
A method of fabricating a light emitting diode device comprises depositing conductive material to cover a portion of surface of a conductive and reflective layer to form a first contact pad, and surfaces between adjacent first trenches to form a second contact pad; and depositing a first passivation layer over uncovered portion of surface of the conductive and reflective layer to form a first planar passivation contact surface between the first contact pad and the second trench and depositing bonding material to cover a portion of surface of the first contact pad, a portion of the second contact pad and a portion of the first planar passivation contact to form a first light emitting diode bonding pad on the first contact pad, a second light emitting diode bonding pad on the second contact pad, and a third light emitting diode bonding pad on the first planar passivation contact.
US09006001B2 Simple scatterometry structure for Si recess etch control
Dimensions of structures in integrated circuits are shrinking with each new fabrication technology generation. Maintaining control of profiles of structures in transistors and interconnects is becoming more important to sustaining profitable integrated circuit production facilities. Measuring profiles of structures with many elements in integrated circuits, such as MOS transistor gates with recessed regions for Si—Ge epitaxial layers, is not cost effective for the commonly used metrology techniques: SEM, TEM and AFM. Scatterometry is technically unfeasible due to the number of elements and optical constants. The instant invention is a simplified scatterometry structure which reproduces the profiles of a structure to be profiled in a simpler structure that is compatible with conventional scatterometric techniques. A method of fabricating a transistor and an integrated circuit using the inventive simplified scatterometry structure are also disclosed.
US09006000B2 Tj temperature calibration, measurement and control of semiconductor devices
A semiconductor device, such as a semiconductor die, is disclosed including embedded temperature sensors for scanning the junction temperature, Tj, at one or more locations of the semiconductor die while the die is operating. Once a temperature of a hot spot is detected that is above a temperature specified for the die or package containing the die, the die/package may be discarded. Alternatively, the functionality of the die may be altered in a way that reduces the temperature of the hot spots.
US09005994B2 Methods for biomolecule and biomolecule complex (BMC) detection and analysis and the use of such for research and medical diagnosis
The present application pertains to improved methods of detecting biomolecules in a biological sample (or system), In particular, embodiments discussed herein allow for the detection of biomolecule complexes. The embodiments enable for the first time the elucidation of the significance of biomolecule complexes for certain disease states, which in turn enables the diagnosis of disease states based on the identity and complexing level of a biomolecule complex in a particular biological sample.
US09005991B2 Device and method for testing biological samples
Devices and methods for testing a biological sample for an analyte of interest are provided that make use of a reaction chamber for receiving a reaction mixture, a housing positioned below the reaction chamber for receiving a test cassette, and a door that is positioned in the top portion of the housing. The door includes a ramp that extends downwardly into the housing such that biasing the ramp upwards opens the door into the cavity of the reaction chamber and places the reaction chamber in fluid communication with the insertion area to thereby allow the reaction mixture to flow onto a test cassette and allow for the determination of an amount of an analyte of interest.
US09005988B2 Method to assess multiphase fluid compositions
A method for the assessment of a multiphase (aqueous and organic) sample phase, the method comprising adding at least one detection molecule to the multiphase sample; detecting a signal emitted from the detection molecule/multiphase sample mixture, the signal being detectably different when the at least one detection molecule is present in one of either an organic phase, an aqueous phase or an interface between said organic phase and said aqueous phase of the multiphase sample; and analyzing the detected signal to assess the properties of a phase or an interface between phases. A system for use in such a method, use of at least one detection molecule for the assessment of a multiphase sample, and a composition for use in the assessment of a multiphase sample are also disclosed.
US09005987B2 Methods for quantitative target detection and related devices and systems
Described herein are methods for quantitative target detection in a sample through use of microbeads and related devices and systems.
US09005984B2 Determining feline proBNP
Methods and compositions are disclosed for determining feline proBNP or fragments thereof in a sample. In one method, feline proBNP or fragments thereof are determined by providing a feline sample, contacting the sample with at least one antibody that binds an epitope in the region from amino acids 68 to 80 of feline proBNP, and determining the presence of the feline proBNP or fragments thereof present in the sample. Antibodies that bind feline proBNP and kits comprising such antibodies are also disclosed.
US09005983B2 Electro-chemical sensor
The present invention provides an electrochemical sensor having a solid electrically conductive substrate and a compound immobilized thereon which has binding affinity for an analyte species to be detected and also displays electrochemical behavior which is modified upon binding of that analyte species, so that binding of an analyte species can be detected by measuring electrochemical properties, such as by voltammetry. Desirably the immobilized compound contains both a first moiety with binding affinity for the analyte and a separate second moiety which is a redox system whose electrochemical oxidation/reduction properties become modified when the first moiety binds the analyte. The analyte binding moiety may be a diol or polyol and preferably is a sugar. The electrochemical sensor finds use in methods of analyzing reservoir and process fluids, particularly at a subterranean location. The electrochemical sensor may be a component of a downhole tool, adapted for deployment downhole.
US09005979B2 Method for determining origin of alcohol or sugar containing products
A method for determining origins of food products, and more specifically for determining geographic and/or biological origin of food products containing alcohols or sugars includes preparing an alcohol sample from a product in question, removing exchangeable hydrogen/deuterium atoms from alcohol molecules of the sample, determining the isotopic composition of non-exchangeable hydrogen/deuterium atoms from sample alcohol, and analyzing results for adulteration or determination of product origin. In addition, alcohol δ13C and δ18O isotopic values, along with δ18O isotopic value of the product water are used for the analysis. Products containing sugar are also subjected to tightly controlled fermentation.
US09005975B2 Method for selecting clone of induced pluripotent stem cells
To efficiently identify and select a clone from clones of induced pluripotent stem cells (iPS cell) having low tumor formation rate in vivo when allowed to differentiate and transplanted in a living body, iPS cells of the clones are induced to differentiate, undifferentiated cells among the cells after the induction of differentiation are detected, and a clone having the content of the undifferentiated cell below a control is selected.
US09005973B2 Targeted genomic modification with partially single-stranded donor molecules
Disclosed herein are donor molecules comprising single-stranded complementary regions flanking one or more sequences of interest. The donor molecules and/or compositions comprising these molecules can be used in methods for targeted integration of an exogenous sequence into a specified region of interest in the genome of a cell.
US09005970B2 Method of culturing cells under regulation in the extension direction
[PROBLEMS] Relating to a bioassay method with the use of cultured cells and cell culture for a therapeutic purpose in the case of determining the efficacy of a drug or the like or examining the toxicity thereof, it is intended to provide a method of culturing cells under regulation in the extension direction and a cell culture plate. [MEANS FOR SOLVING PROBLEMS] A cell culture plate having a plural number of side walls (1) and a plural number of space structures (3) for providing cultured cells which are formed by the side walls (1), wherein the side walls (1) are provided with openings (2) so that the space structures (3) are linked together. By using this cell culture plate, a method of culturing cells under regulation in the extension direction can be provided.
US09005964B2 Endodermal progenitor cells
The present invention relates to endodermal progenitor cells and methods of isolation, culture, differentiation and use thereof.
US09005963B2 Amino acid sequences directed against cellular receptors for viruses and bacteria
The present invention relates to amino acid sequences that are directed against (as defined herein) human cellular receptors for viruses and/or bacteria such as e.g. NANOBODIES specifically recognizing hCD4, hCXCR4, hCCR5, hTLR4, human alphaV integrin, human beta3 integrin, human beta1 integrin, human alpha2 integrin, hCD81, hSR-BI, hClaudin-1, hClaudin-6 and hClaudin-9, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. The amino acid sequences may be used to prevent human cell entry of HIV, HCV, adenoviruses, hantavirus, herpesvirus, echo-virus 1 and others.
US09005962B2 Regionalised endoderm cells and uses thereof
The present invention relates to the generation of anterior definitive endoderm (ADE) cells from embryonic stem cells and the differentiation of such cells to, for example, pancreatic or liver cells. The invention also relates to cell lines, cell culture methods, cells markers and the like and their potential uses in a variety of applications.
US09005961B2 Infectious cDNA of an approved vaccine strain of measles virus, use for immunogenic compositions
The invention relates to a cDNA molecule which encodes the nucleotide sequence of the full length antigenomic (+)RNA strand of a measles virus (MV) originating from an approved vaccine strain, for example, the Schwarz strain. It also concerns the preparation of infectious recombinant viruses and immunogenic compositions using the cDNA.
US09005958B2 Cell or tissue cultivation apparatus and method of cultivation
A cultivation apparatus and a cultivation method of a culture such as a cell or tissue. Provided are an incubator unit for accommodating a culture and a lever that penetrates through the incubator unit and can move in circular arc around a fulcrum as a center, the fulcrum being set at a wall of the incubator unit or in the vicinity thereof, then displacement is imparted to the culture by operating the lever. Bending force can be acted on the culture (cell construct) such as a cell or tissue, so that without any increase or decrease of a culture fluid in the incubator unit, namely, without any increase or decrease of pressure to the culture fluid, displacement required for cultivation can be imparted to the culture in the incubator unit. By curving, continuous compression and extension are generated in a direction of thickness from a concave portion to a convex portion of the curving.
US09005956B2 Method for extracting phosphorous from solids using active leaching and phosphate-accumulating microorganisms
The present invention relates to a method of selectively obtaining phosphorus from solids containing heavy metals and phosphate. In this method, the solid is treated under acidic aerobic conditions using microorganisms comprising leaching microorganisms and polyphosphate-accumulating microorganisms, so that the heavy metals and the phosphates are released from the solid and the released phosphates may be taken up by the polyphosphate-accumulating microorganisms. The phosphorus-enriched biomass that is obtained in this manner is separated and may be utilized, e.g., as organic fertilizer.
US09005954B2 Methods for isolating bacteria
The present invention relates to compositions and methods to identify novel bacteria and metabolites derived therefrom. More specifically, the invention describes a novel method to isolate bacteria producing metabolites of interest from environmental samples. Particularly, the invention discloses a method to select rare antibiotic producing bacteria. The invention can be used from any sample and allows the isolation of bacteria having e.g., pharmaceutical or agrochemical interest.
US09005953B2 Recombinant microorganism having butanol production capacity and butanol production method
This invention relates to a recombinant microorganism having improved butanol production capacity and butanol production with the use of such recombinant microorganism with good efficiency. In this invention, the acetoacetyl-CoA synthase gene encoding an enzyme capable of synthesizing acetoacetyl-CoA from malonyl-CoA and acetyl-CoA and a group of genes involved in butanol biosynthesis that enables synthesis of butanol from acetoacetyl-CoA are introduced into a host microorganism.
US09005949B2 Pregnancy-associated plasma protein-A2 (PAPP-A2) polynucleotides
The present invention provides pregnancy associated plasma protein A2 (PAPP-A2), its nucleotide and amino acid sequences, antisense molecules to the nucleotide sequences which encode PAPP-A2, expression vectors for the production of purified PAPP-A2, antibodies capable of binding specifically to PAPP-A2, hybridization probes or oligonucleotides for the detection of PAPP-A2-encoding nucleotide sequences, genetically engineered host cells for the expression of PAPP-A2, and methods for screening for pathologies in pregnant and non-pregnant patients. Methods for screening for altered focal proliferation states in pregnant and/or non-pregnant patients, which include detecting levels of PAPP-A2, are also described.
US09005948B2 EGVII endoglucanase and nucleic acids encoding the same
The present invention provides a novel endoglucanase nucleic acid sequence, designated egl7, and the corresponding EGVII amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding EGVII, recombinant EGVII proteins and methods for producing the same.
US09005947B2 BGL7 beta-glucosidase and nucleic acids encoding the same
The present invention provides a novel β-glucosidase nucleic acid sequence, designated bgl7, and the corresponding BGL7 amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BGL7, recombinant BGL7 proteins and methods for producing the same.
US09005946B2 Variant endoglucanases and related polynucleotides
The invention provides variants of the Clostridium thermocellum endoglucanase (CelG) that have improved endoglucanase activity compared to the wild type enzyme. Also provided are related polynucleotides, compositions, vectors, host cells, and methods of use.
US09005944B2 Bone cell delivery device
Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to subjects.
US09005942B2 Enhanced animal cell growth using ultrasound
A method of increasing the rate of growth of an animal cell or cell culture include the use of ultrasound at a frequency greater than about 1 MHz.
US09005937B2 Dual cofactor specific ribitol dehydrogenase and use thereof
There are provided a novel ribitol dehydrogenase, a residue determining double coenzyme specificity, and a method for preparing L-ribulose using the same, and more particularly, to a ribitol dehydrogenase producing rare sugars, nucleic acid molecules encoding the same, a vector including the nucleic acid molecules, a transformant including the vector, a mutant of the ribitol dehydrogenase, and a method for preparing L-ribulose using the ribitol dehydrogenase. The ribitol dehydrogenase having double coenzyme specificity, which is derived from Zymomonas mobilis, can effectively be used for preparing high-priced rare sugars and an investigation of coenzyme specificity determinants for the ribitol dehydrogenase is applied for all of dedydrogenases as a based technique.
US09005936B2 Liquefied biomass
The invention is directed to a liquefied sugar beet and/or sugar cane biomass material as well as production methods and uses thereof. The liquefied biomass is storage stable and can be used for the production of a product resulting from fermentation.
US09005927B2 Multi-chain eukaryotic display vectors and uses thereof
A eukaryotic expression vector capable of displaying a multi-chain polypeptide on the surface of a host cell is provided, such that the biological activity of the multi-chain polypeptide is exhibited at the surface of the host cell. Such a vector allows for the display of complex biologically active polypeptides, e.g., biologically active multi-chain polypeptides such as immunoglobulin Fab fragments. The present invention describes and enables the successful display of a multi-chain polypeptide on the surface of a eukaryotic host cell. Preferred vectors are described for expressing the chains of a multi-chain polypeptide in a host cell separately and independently (e.g., under separate vector control elements, and/or on separate expression vectors, thus forming a matched vector set). The use of such matched vector sets provides flexibility and versatility in the generation of eukaryotic display libraries, for example the ability to generate and to display multi-chain polypeptides by combining and recombining vectors that express variegations of the individual chains of a multi-chain polypeptide. Entire repertoires of novel chain combinations can be devised using such vector sets.
US09005922B2 Sensor chip for screening topoisomerase inhibitor and screening method thereof
The present invention discloses a sensor chip for screening a topoisomerase inhibitor and a screening method thereof. The sensor chip comprises topoisomerase I and a biochip. The topoisomerase I is immobilized on the biochip, and the topoisomerase I has DNA catalytic activity. This provides a rapid screening method for topoisomerase I inhibitors.
US09005919B2 Method and device for the production of a fertilizer precursor and of a fertilizer
The invention relates to a method and a device for the production of a fertilizer precursor or of a fertilizer. The method comprises the following method steps: a) production of an acidic source solution (05) in which at least one organic acid is present in dissolved form; b) addition of the acidic source solution (05) to at least one substance containing minerals; c) artificial weathering of the minerals present in the substance containing minerals by means of the source solution. The device for producing organomineral fertilizer comprises at least one device for providing an organomineral compound or a substance containing minerals, at least one device for at least one mechanical preprocessing of the organo-mineral compound and at least one solution storage device (50) which comprises an outlet device (51) which makes possible a release of an acidic source solution (05) onto the provided mechanically pretreated compound, wherein an addition of the acidic source solution (05) to the compound triggers at least the technical weathering of the minerals comprised in the substrate.
US09005917B2 Variable color two-photon fluorescent probe, method for imaging thiol activation in mitochondrion using same, and method for manufacturing the variable color two-photon fluorescent probe
The present invention relates to a two-photon fluorescent probe, more particularly a two-photon fluorescent probe represented by Formula 1, a method for preparing same and a method for imaging thiols in mitochondria using same. The two-photon fluorescent probe according to the present invention, having two probes introduced in one molecule, can selectively dye mitochondria and emit intense fluorescence by reacting with thiols. Accordingly, it can be used to image the distribution and activation of thiols in a living cell or an intact living tissue.
US09005916B2 Blood cell analyzer, blood cell analyzing method, and non-transitory storage medium
The present invention is a blood cell analyzer. When only measuring one or more measurement items included in one group, a first sample supplying operation is performed which includes aspirating a blood sample by a first amount. When measuring one or more measurement items included in the one group and another measurement item not included in the one group, a second sample supplying operation and a third sample supplying operation are performed. The second sample supplying operation includes aspirating the blood sample by the first amount for the measurement items included in the one group, and the third sample supplying operation includes aspirating the blood sample by a second amount for the another measurement item.
US09005915B2 Method for in vitro blood testing
Method for determining the presence of a malady in a patient by measuring the degree of reaction of individual types of white blood cells (basophils, eosinophils, neutrophils, monocytes and lymphocytes) in the patient's blood. The degree of reaction of each type of white blood cells is determined by comparing the volumetric size distributions of the types of white blood cells before and after exposure to suspected reactants. Positive results of a change in the volumetric size distribution of the individual types of white blood cells in response to exposure to a specific reactant indicates the presence of a specific malady, such as an allergic reaction to the suspected reactant.
US09005912B2 Hybridoma cell line for producing antibody for type II collagen
The present invention provides a hybridoma cell line (DSM ACC3145), wherein the hybridoma cell line produces an antibody which specifically binds to an amino acid sequence of type II collagen comprising: K-G-E-P-G-D-D-G-P-S-C (as set forth in SEQ ID NO. 1); and a method for detecting osteoarthritis, by identifying a presence of type II collagen in a urine sample through containing the urine sample with the said antibody.
US09005911B2 Methods for identifying inhibitors of botulinum neurotoxins
A system and method for identifying a botulinum neurotoxin inhibitor employing a botulinum neurotoxin substrate complex having a peptide substrate, preferably SNAP-25, a reporter domain on one side of said peptide substrate and an immobilization domain on the opposite side of said peptide substrate. The botulinum neurotoxin inhibitor is identified by its ability to decrease the relative amount of cleaved complex, detected through measuring a decrease in complex bound to a solid support. The method of the present invention also utilizes novel cells that express a botulinum neurotoxin substrate complex. Also provided are novel stable cell lines that express the botulinum toxin substrate complex and viral vectors capable of efficiently expressing an active light chain of the BoNT within mammalian cells.
US09005909B2 Whole blood assay for measuring AMPK activation
A method of sample analysis is provided. In certain embodiments, the method comprises: a) labeling cells of a blood sample using an antibody that specifically binds to phospho-AMPK or a phosphorylated target thereof, to produce a labeled sample; and b) measuring antibody binding by a population of blood cells of the labeled sample using flow cytometry. In particular embodiments, the method may further comprise, prior to the labeling step: contacting blood with a test agent ex vivo or in vivo; and comparing the evaluation to results obtained from a reference sample of blood cells.
US09005908B2 Mycobacterial infections
The present invention relates to Mycobacterial infections and provides a method of diagnosing infections of Mycobacterium avium subsp. paratuberculosis (Map), the causative agent of Johne's disease. In addition, the invention also provides as kits for use in the diagnosis of Map infections and vaccines/immunogenic compositions.
US09005906B2 Tetrahydropyran nucleic acid analogs
The present disclosure describes tetrahydropyran nucleoside analogs, oligomeric compounds prepared therefrom and methods of using the oligomeric compounds. More particularly, tetrahydropyran nucleoside analogs are provided, having one or more chiral substituents, that are useful for enhancing properties of oligomeric compounds including nuclease resistance and binding affinity. In some embodiments, the oligomeric compounds provided herein hybridize to a portion of a target RNA resulting in loss of normal function of the target RNA.
US09005904B2 Risk markers for cardiovascular disease
Provided herein methods for determining whether a subject, particularly a human subject, is at risk of developing, having, or experiencing a complication of cardiovascular disease, and methods of treating subjects who are identified by the current methods of being at risk for cardiovascular disease. In one embodiment, the method comprises determining levels of one or more oxidized apolipoprotein A-I related biomolecules in a bodily sample from the subject. Also, provided are kits and reagents for use in the present methods. Also provided are methods for monitoring the status of cardiovascular disease in a subject or the effects of therapeutic agents on subjects with cardiovascular disease. Such method comprising determining levels of one or more oxidized apolipoprotein A-I related molecules in bodily samples taken from the subject over time or before and after therapy.
US09005902B2 Tuberculosis diagnostic test
A method of diagnosing in a host infection by or exposure to a mycobacterium which expresses ESAT-6 comprising (i) contacting a population of T cells from the host with one or more peptides or analogues selected from the peptides represented by SEQ ID NO:1 to 11 and analogues thereof which can bind a T cell receptor which recognises any of the said peptides, and (ii) determining whether the T cells of said T cell population recognise the peptide(s) and/or analogue(s). The method may performed in vivo. Peptides and a kit which enable the method to be carried out are provided.
US09005900B2 TLE3 as a marker for chemotherapy
Methods of using TLE3 as a marker for predicting the likelihood that a patient's cancer will respond to chemotherapy. Methods of using TLE3 as a marker for selecting a chemotherapy for a cancer.
US09005897B2 Method of deriving progenitor cell line
We disclose a method comprising: (a) providing an embryonic stem (ES) cell; and (b) establishing a progenitor cell line from the embryonic stem cell; in which the progenitor cell line is selected based on its ability to self-renew. Preferably, the method selects against somatic cells based on their inability to self-renew. Preferably, the progenitor cell line is derived or established in the absence of co-culture, preferably in the absence of feeder cells, which preferably selects against embryonic stem cells. Optionally, the method comprises (d) deriving a differentiated cell from the progenitor cell line.
US09005896B2 Method for amplifying nucleic acids
The present invention describes methods for amplifying a target nucleic acid wherein target nucleic acids hybridize to capture probe nucleic acids which are immobilized to a support via their 5′ end. The hybridization product is further extended with a polymerase to form a double stranded nucleic acid. To this double stranded nucleic acid, a hairpin nucleic acid is ligated. This ligation product is further amplified and sequenced.
US09005894B2 Determination of KIR haplotypes associated with disease
Disclosed is a method of determining KIR genotypes for one or more individuals in parallel, the method comprising: for each individual, amplifying the polymorphic exon sequences of the KIR genes, pooling the KIR amplicons, performing emulsion PCR followed by pyrosequencing in parallel to determine all the amplicon sequences present in the individual to determine which KIR alleles are present in the individual.
US09005887B2 Detection of an analyte in a sample
There is provided mechanisms for the detection of an analyte in a sample. The mechanisms utilize at least a first measurement channel comprising a detection reactant corresponding to the analyte to be detected, and at least a microstructure associated with the first measurement channel. When the mechanisms are in use, the sample is introduced into the first measurement channel and propagated by way of the first measurement channel towards the microstructure. If the analyte is present in the sample, the analyte interacts with the detection reactant to form a networked product, and the microstructure is configured to filter the networked product.
US09005886B2 Method for cryopreservation of human spermatozoa free from seminal plasma using a fast and simple aseptic vitrification-devitrification process; portable kit for carrying out the method; and use of the same for treatment of disorders related to reproductive failures
The present invention discloses a method for cryopreservation of human spermatozoa: the method comprises providing spermatozoa free from seminal liquid; mixing the spermatozoa with vitrification medium, wherein the main cryoprotectant agent is 0.1-0.3 M sucrose; placing the sample inside straws and rapidly freezing them; refrigerating the straws with no need of liquid N2; and devitrifying the sample in a medium of the present invention. The present invention furthermore discloses a portable kit that makes easy to implement the method, said kit comprising vitrification and devitrification solutions in the volumes required to develop the method and the physical support to carry out the same, i.e. the straws. The use of this kit is also disclosed for the treatment of disorders related to reproductive failures.
US09005881B2 Method of lithography
A lithography method of manufacturing integrated circuits is disclosed. A combination photoalignment-photoresist layer is formed on a substrate. A treatment is performed on the combination photoalignment-photoresist layer. The combination photoalignment-photoresist layer is exposed to a predetermined pattern. The combination photoalignment-photoresist layer is developed to form a pattern and expose a portion of the substrate.
US09005878B2 Forming patterns using thiosulfate polymer compositions
A thiosulfate polymer composition includes an electron-accepting photosensitizer component, either as a separate compound or as an attachment to the thiosulfate polymer. The thiosulfate polymer composition can be applied to various articles and used to form a predetermined polymeric pattern after photothermal reaction to form crosslinked disulfide bonds, removing non-crosslinked polymer, and reaction with a disulfide-reactive material.
US09005877B2 Method of forming patterns using block copolymers and articles thereof
A method for patterning a layered structure is provided that includes performing photolithography to provide a developed prepattern layer on a horizontal surface of an underlying substrate, modifying the prepattern layer to form spaced apart inorganic material guides, casting and annealing a layer of a self-assembling block copolymer to form laterally-spaced cylindrical features, forming a pattern by selectively removing at least a portion of one block of the self-assembling block copolymer, and transferring the pattern to the underlying substrate. The method is suitable for making sub-50 nm patterned layered structures.
US09005875B2 Pre-patterned hard mask for ultrafast lithographic imaging
A method of fabricating a substrate including coating a first resist onto a hardmask, exposing regions of the first resist to electromagnetic radiation at a dose of 10.0 mJ/cm2 or greater and removing a portion of said the and forming guiding features. The method also includes etching the hardmask to form isolating features in the hardmask, applying a second resist within the isolating features forming regions of the second resist in the hardmask, and exposing regions of the second resist to electromagnetic radiation having a dose of less than 10.0 mJ/cm2 and forming elements.
US09005874B2 Compound, polymeric compound, acid generator, resist composition, and method of forming resist pattern
There are provided a novel compound, a polymeric compound, a resist composition, an acid generator and a method of forming a resist pattern the compound represented by general formula (1-1): wherein each of R1 and R3 independently represents a single bond or a divalent linking group; A represents a divalent linking group; each of R2 and R4 independently represents a hydroxyl group, a hydrocarbon group which may have a substituent, or a group represented by general formula (1-an1), (1-an2) or (1-an3), provided that at least one of R2 and R4 represents a group represented by general formula (1-an1), (1-an2) or (1-an3); and n0 is preferably 0 or 1, and wherein Y1 represents a single bond or —SO2—; R5 represents a linear or branched monovalent hydrocarbon group of 1 to 10 carbon atoms, cyclic monovalent hydrocarbon group of 3 to 20 carbon atoms or monovalent hydrocarbon group of 3 to 20 carbon atoms having a cyclic partial structure which may be substituted with a fluorine atom; and M+ represents an organic cation or a metal cation,
US09005871B2 Sulfonium derivatives and the use therof as latent acids
Compounds of the formula (I), wherein Ar1 is for example phenylene or biphenylene both unsubstituted or substituted; Ar2 and Ar3 are for example independently of each other phenyl, naphthyl, biphenylylyl or heteroaryl, all optionally substituted; or Ar1 and Ar2 for example together with a direct bond, O, S or (CO), form a fused ring system; R is for example hydrogen, C3-C30cycloalkyl or C1-C18alkyl; and R1, R2 and R3 independently of each other are for example C1-C10haloalkyl; are effective photoacid generators (PAG).
US09005869B2 Developing agent and method for producing the same
A method for producing a developing agent including preparing a dispersion liquid containing first fine particles containing a binder resin and second fine particles containing a color developable compound, a color coupler, and a color eraser, and aggregating the first and second fine particles in the dispersion liquid to form aggregated particles.
US09005867B2 Porous toner and process for making the same
A process includes forming a filter cake from a slurry of emulsion aggregation toner particles and washing the filter cake with an alcohol to create porous toner particles.
US09005864B2 Toner, two-component developer and image forming apparatus
A toner including: toner base particles; and an external additive, the toner base particles each comprising a binder resin and a colorant, wherein the external additive comprises non-spherical particles and spherical particles, wherein the non-spherical particles are each a secondary particle in which spherical primary particles are coalesced together, and wherein the non-spherical particles and the spherical particles in the external additive satisfy a relationship expressed by the following formula (1): 3Ca(%)
US09005856B2 Hydroxygallium porphyrazine derivative mixture and electrophotographic photoconductor
A hydroxygallium porphyrazine derivative mixture including: a plurality of different hydroxygallium porphyrazine derivatives each represented by the following General Formula (A-2): where A1, A2, A3, A4, B1, B2, B3 and B4 each independently represent a nitrogen atom or a carbon atom bonded to hydrogen, with the proviso that both of A1 and B1 are carbon atoms each bonded to hydrogen or only one of A1 and B1 is a nitrogen atom, both of A2 and B2 are carbon atoms each bonded to hydrogen or only one of A2 and B2 is a nitrogen atom, both of A3 and B3 are carbon atoms each bonded to hydrogen or only one of A3 and B3 is a nitrogen atom, and both of A4 and B4 are carbon atoms each bonded to hydrogen or only one of A4 and B4 is a nitrogen atom.
US09005851B2 Phase shift mask blank and phase shift mask
The present invention provides a photomask blank used for producing a photomask to which an ArF excimer laser light is applied, wherein: a light-shielding film is provided on a light transmissive substrate; the light-shielding film has a laminated structure in which a lower layer, an interlayer and an upper layer are laminated in this order from the side close to the light transmissive substrate; the thickness of the entire light-shielding film is 60 nm or less; the lower layer is made of a film containing a metal and has a first etching rate; the upper layer is made of a film containing a metal and has a third etching rate; the interlayer is made of a film containing the same metal as that contained in the lower layer or the upper layer and has a second etching rate that is lower than the first etching rate and the third etching rate; and the thickness of the interlayer is 30% or less of the thickness of the entire light-shielding film.
US09005849B2 Photomask having a reduced field size and method of using the same
A photomask used for manufacturing a semiconductor device includes a substrate; and one or more layers disposed over the substrate, the one or more layers defining a full field area and a reduced field area with a primary pattern being formed in the reduced field area, wherein the full field area is defined by a width of at least 90 mm and a length of at least 100 mm, and the reduced field area is defined by a width within the range of approximately 20-80 mm and a length within the range of approximately 20-80 mm, a center point of the primary patterned area being spaced a predetermined distance from a center point of the photomask so that the primary patterned area avoids photomask defects.
US09005848B2 Photomask having a reduced field size and method of using the same
A photomask used for manufacturing a semiconductor device includes a substrate; and one or more layers disposed over the substrate, the one or more layers defining a full field area and a reduced field area with a primary pattern being formed in the reduced field area, wherein the full field area is defined by a width of at least 90 mm and a length of at least 100 mm, and the reduced field area is defined by a width within the range of approximately 20-80 mm and a length within the range of approximately 20-80 mm.
US09005847B2 Fuel cell fabrication using photopolymer based processes
A method for fabricating a fuel cell component includes the steps of providing a mask having a plurality of radiation transparent apertures, a radiation-sensitive material having a sensitivity to the plurality of radiation beams, and a flow field layer. The radiation-sensitive material is disposed on the flow field layer. The radiation-sensitive material is then exposed to the plurality of radiation beams through the radiation transparent apertures in the mask to form a diffusion medium layer with a micro-truss structure.
US09005844B2 Structure of solid oxide fuel cell
On each of upper and lower surfaces of a flat-plate-like support substrate having a longitudinal direction and having fuel gas flow channels formed therein, a plurality of power-generating elements A connected electrically in series are disposed at predetermined intervals along the longitudinal direction. On each of the upper and lower surfaces of the support substrate, a plurality of recesses are formed at predetermined intervals along the longitudinal direction. Each of the recesses is a rectangular-parallelepiped-like depression defined by four side walls arranged in a circumferentially closed manner and a bottom wall. That is, in the support substrate, frames are formed to surround the respective recesses. Fuel electrodes of the power-generating elements A are embedded in the respective recesses.
US09005840B2 Polymer fuel cell stack and polymer fuel cell separator pair
A fuel cell separator pair has first and second separators having front and back surfaces, a corrugated plate portion shaped in a wave form at the central portion, and a flat plate portion formed in the peripheral portion and surrounding the corrugated plate portion, wherein the corrugated plate portion of the front surface constitutes a reaction gas channel and the corrugated plate portion of the back surface constitutes a coolant channel. The back surfaces of the first and second separators are facing each other. The flat plate portions of the first and second separators are arranged on top of each other so as to be in contact with each other. The flat plate portion of the second separator protrudes toward the outside beyond the flat plate portion of the first separator. The fuel cell separator pair has a seal member (A) disposed on the flat plate portion of the front surface of the first separator, a seal member (B) disposed on the flat plate portion of the front surface of the second separator, and a seal member (C) disposed on the region protruding beyond the flat plate portion of the first separator in the flat plate portion of the back surface of the second separator.
US09005837B2 Gasket for fuel cell system manifold seal
A gasket for a manifold seal for a fuel cell system includes a first layer of fibrous ceramic material having a first compressibility, a second layer of fibrous ceramic material having a second compressibility and a third layer of fibrous ceramic material having third compressibility. The third layer of fibrous ceramic material is positioned between and engaged with the first layer of fibrous ceramic material and the second layer of fibrous ceramic material. The third compressibility is less than the first compressibility and less than the second compressibility.
US09005835B2 Fuel cell with reduced mass transfer limitations
This disclosure related to polymer electrolyte member fuel cells and components thereof.
US09005834B2 Polymer electrolyte fuel cell
A polymer electrolyte fuel cell comprises a plurality of stacked cells each having an ionic conductive electrolyte membrane, an anode placed on one side of the electrolyte membrane, a cathode placed on the other side of the electrolyte membrane, and a conductive separator on which a first refrigerant channel for flow of a refrigerant is formed in center part thereof. The separator comprises penetration holes constituting a manifold which extend in a direction of stacking of the plurality of cells and through which the refrigerant flows and second refrigerant channels for communication between the penetration holes and the first refrigerant channel. A plurality of protrusions that protrude into the penetration holes from parts of wall surfaces of the penetration holes that are located peripherally in connection parts between the penetration holes and the second refrigerant channels.
US09005833B2 System having high-temperature fuel cells
The invention relates to a system having high-temperature fuel cells, for example SOFCs. A reformer connected upstream of the high-temperature fuel cells at the anode side, a start burner for the preheating of the cathodes of the high-temperature fuel cells, an afterburner and an operating heat exchanger are present at the system in accordance with the invention. Oxidizing agent can be supplied to the high-temperature fuel cell cathodes through the operating heat exchanger. In addition, it can be heated with the exhaust gas of the high-temperature fuel cells. Exhaust gas conducted through the operating heat exchanger can flow in an exhaust gas line together with environmental air and can then be conducted away into the environment as cooled exhaust gas.
US09005831B2 Offset control arrangement and method for controlling voltage values in a fuel cell system
An offset control arrangement is disclosed for controlling voltage values in a fuel cell system including an anode side, a cathode side and an electrolyte between the anode side and the cathode side. The fuel cell system can include at least one fuel cell array of at least two fuel cells, and at least one load for performing load function. The offset control arrangement can include voltage monitoring for monitoring an input voltage of the load, a control processor for processing the monitoring information, and at least one offsetting source in serial connection to the at least one fuel cell array, with a power level of the offsetting source being substantially low compared to the power level of the fuel cell array, and the offsetting source being arranged to perform at least unidirectional shifting of fuel cell array output voltage.
US09005825B2 Bus bar assembly for an electrochemical cell stack
An electrochemical cell stack assembly is disclosed comprising a member made of an elastic and electrically conductive material placed between a bus bar and a starter plate. The elastic, electrically conducting member covers at least a peripheral region along a perimeter of a recess housing the bus bar to distribute compression forces over an interface area between the bus bar and an insulator end plate, thereby reducing shear stresses in the starter plate when the stack is compressed. An elastic pad also may be arranged in the recess and between the insulator end plate and the bus bar.
US09005824B2 Lithium secondary battery
There is provided a lithium secondary battery including a positive electrode, a negative electrode, a nonaqueous electrolyte liquid and a separator, that is subjected to a constant-current constant-voltage charge with a stop voltage of more than 4.25V before its use. The lithium secondary battery uses the nonaqueous electrolyte liquid having contained 0.1 to 5 mass % of a phosphonoacetate compound represented by the following general formula (1), and having contained 0.1 to 5 mass % of 1,3-dioxane. In General Formula (1), each of R1, R2 and R3 is independently hydrocarbon groups having a carbon number of 1 to 12 with or without substituent of a halogen atom, and n is 0 to 6 integers.
US09005822B2 Functional electrolyte for lithium-ion batteries
Functional electrolyte solvents include compounds having at least one aromatic ring with 2, 3, 4 or 5 substituents, at least one of which is a substituted or unsubstituted methoxy group, at least one of which is a tert-butyl group and at least one of which is a substituted or unsubstituted polyether or poly(ethylene oxide) (PEO) group bonded through oxygen to the aromatic ring, are provided.
US09005821B2 Secondary battery
A nonaqueous electrolyte secondary battery includes: a positive electrode; a negative electrode; and a nonaqueous electrolyte, wherein an open circuit voltage in a completely charged state per pair of a positive electrode and a negative electrode is from 4.25 to 6.00 V; and at least one member selected from the group consisting of sulfonic anhydrides represented by the following formulae (1) to (4) is contained in a nonaqueous electrolytic solution
US09005819B2 Anode for secondary battery and secondary battery having the same
The present invention relates to an anode for a secondary battery, comprising: a wire-type current collector; a metal-based anode active material layer formed on the surface of the wire-type current collector, and comprising a metallic active material; and a graphite-based anode composite layer formed on the surface of the metal-based anode active material layer, and comprising a mixture of a graphite-based active material, a conductive material and a first polymer binder.The anode of the present invention has the metal-based anode active material layer together with the graphite-based anode composite layer acting as a buffer, thereby preventing the metallic active material from being isolated or released even if excessive volume expansion occurs during charging and discharging processes. Also, the graphite-based anode composite layer has good affinity with an organic electrolyte solution to compensate the defect of the metallic active material having low affinity with an organic electrolyte solution.
US09005815B2 Negative active material for rechargeable lithium battery, method of preparing same, and rechargeable lithium battery
A negative active material for a rechargeable lithium battery, a method of manufacturing the same, and a rechargeable lithium battery including the negative active material. The negative active material includes carbon particles having interplanar spacing (d002) ranging from about 0.34 nm to about 0.50 nm at a 002 plane, measured by X-ray diffraction using CuKα, and nitrogen on the surface of the carbon particles.
US09005805B2 Secondary battery of novel structure
Disclosed herein is a plate-shaped secondary battery configured to have a structure in which an electrode assembly of a cathode/separator/anode structure is mounted in a battery case in a sealed state by thermal welding, wherein a protuberance is formed at an outer edge sealed portion of an electrode assembly receiving part of the battery case such that the protuberance protrudes upward and downward from the sealed portion, and the protuberance extends along the outer edge of the electrode assembly receiving part continuously in a curved line or in a straight line in a state in which the protuberance is adjacent to the electrode assembly receiving part.
US09005801B2 Battery module, electronic apparatus, electric power storage system, electric power system, and electric vehicle
A battery module includes a plurality of battery supports each having a face orthogonal to the stacking direction, and a side face, the battery supports each containing a plurality of cells and being made of an insulating material, a coupling part that is located between the face of one battery support and the face of another adjacent battery support, and contracts in the stacking direction upon stacking the battery supports to bring the faces of the battery supports into intimate contact, a group of cells including the battery supports stacked with the coupling part being placed between the battery supports, a base plate, and first and second regulating plates placed facing each other in a standing position on the base plate, the first and second regulating plates sandwiching the group of cells arranged between the first and second regulating plates and stacked with the coupling part being contracted.
US09005793B2 Energy storage article and method
Systems and methods for obtaining and/or maintaining a column height of an electrolyte relative to a separator surface within an energy storage device. Embodiments of the invention provide a wicking component, a current collector, and a bias component. The current collector is positioned to force the bias component to press the wicking component tight to an inner surface of a separator. The bias component maintains contact between the wicking component and the surface of separator and creates a capillary gap in which sodium wicks.
US09005789B2 Jelly-roll type electrode assembly pattern-coated with active material and secondary battery including the same
Provided is a jelly-roll type electrode assembly pattern-coated with active materials manufactured by winding and compressing a separator and an anode and a cathode arranged on both sides of the separator. The anode includes anode flat coated portion coated with an anode active material and anode curved uncoated portion not coated with the anode active material, which are alternately formed. The cathode includes a cathode flat coated portion coated with a cathode active material and a cathode curved uncoated portion not coated with the cathode active material, which are alternately formed.
US09005787B2 Secondary battery
A secondary battery, in which working pressure and rupture pressure of a safety vent are effectively controlled with respect to a slope of the safety vent and shapes of rupturable grooves. The secondary battery includes an electrode assembly arranged within a can, a cap assembly coupled to the can and including a lower portion arranged above the electrode assembly and having a through-hole arranged at a center thereof, a safety vent electrically connected to the electrode assembly through the through-hole and an insulator arranged between the safety vent and the lower portion of the cap assembly, wherein a first distance between a portion of the safety vent arranged at a region near the through-hole and the lower portion of the cap assembly is smaller than a second distance between a portion of the safety vent positioned furthest from the through-hole and the lower portion of the cap assembly.
US09005782B2 Magnetic disk and method of manufacturing the same
Provided is a magnetic disk that is excellent in durability, particularly in LUL durability and CFT properties, and thus has high reliability despite the low flying height of a magnetic head following the rapid increase in recording density in recent years and despite the very strict environmental resistance following the diversification of applications. A magnetic disk (10) has at least a magnetic layer (6), a carbon-based protective layer (7), and a lubricating layer (8) provided in this order over a substrate (1). The lubricating layer (8) contains a compound having a perfluoropolyether main chain in a structure thereof and having a polar group other than at ends of a molecule thereof.
US09005777B2 Heterocyclic compound, organic light-emitting diode including the heterocyclic compound, and flat display device including the organic light-emitting diode
A heterocyclic compound represented by Formula 1 below, and an organic light-emitting diode including the heterocyclic compound, and a flat display device including the organic light-emitting diode. wherein Ar1 to Ar4, X1, X2, Y1, Y2, L1, and m are defined as in the specification.
US09005775B2 Composition, film using the composition, charge transport layer, organic electroluminescence device, and method for forming charge transport layer
A composition includes: (B) an arylamine derivative having at least one polymerizable group; and (A) a cyano group-free azo based polymerization initiator.
US09005769B2 Substrate for wear-proof orthopaedic joints, of non ferrous metal with a nitride-based coating
Substrates for joints for orthopaedic implants are described, wherein at least one of the sliding surfaces of non-ferrous metal alloys, in particular of cobalt, chromium, molybdenum alloys, has a coating consisting of niobium nitride nanolayers alternating with chromium nitride nanolayers, the lot being protected by a chromium nitride microlayer.
US09005766B2 Biaxially-oriented polyester film for use as wrap-around container label, and wrap-around container label
The invention provides a biaxially-oriented polyester film that comprises a biaxially oriented polyethylene terephthalate film and contains 9000 ppm or less of ethylene terephthalate cyclic trimer, has a molten specific resistance of within 1.0×108Ω·cm, and at least one surface of the film has a surface resistivity of 13 log Ω or less under a relative humidity of 65 %. The invention also provides a wrap-around label for a container produced from the film.
US09005763B2 Barrier layers comprising Ni-inclusive ternary alloys, coated articles including barrier layers, and methods of making the same
Certain example embodiments relate to Ni-inclusive ternary alloy being provided as a barrier layer for protecting an IR reflecting layer comprising silver or the like. The provision of a barrier layer comprising nickel, chromium, and/or molybdenum and/or oxides thereof may improve corrosion resistance, as well as chemical and mechanical durability. In certain examples, more than one barrier layer may be used on at least one side of the layer comprising silver. In still further examples, a NixCryMoz-based layer may be used as the functional layer, rather than or in addition to as a barrier layer, in a coating.
US09005757B2 Metal-salen complex compound and method for producing the same
The present invention provides a metal-salen complex compound having a controlled grain size that enables the metal-salen complex compound to exert its pharmacological effects as a medicine, at a target region. This metal-salen complex compound is composed of the following that has a crystal grain size of 8 μm or less, and that is represented by the chemical formula below. N,N′-Bis(salicylidene)ethylenediamine metal M is Fe, Cr, Mn, Co, Ni, Mo, Ru, Rh, Pd, W, Re, Os, Ir, Pt, Nd, Sm, Eu, or Gd.
US09005753B2 Fibers of UHMWPE and a process for producing thereof
The invention relates to a process for producing gel-spun ultra high molecular weight polyethylene (UHMWPE) fibres having high tensile strengths and improved creep rates wherein the UHMWPE used in said process is characterized by a difference in the phase angle according to Formula (1) Δδ=δ0.001−δ100 of at most 42°, wherein δ0.001 is the phase angle at an angular frequency of 0.001 rad/sec; and δ100 is the phase angle at an angular frequency of 100 rad/sec as measured with a frequency sweep dynamic rheological technique at 150° C. on a 10% solution of UHMWPE in paraffin oil, provided that δ100 is at most 18°. The invention further relates to gel-spun UHMWPE fibres produced thereof. The gel-spun UHMWPE fibres of the invention have a tensile strength of at least 4 GPa, and a creep rate of at most 5×10−7 sec−1 as measured at 70° C. under a load of 600 MPa. The gel-spun UHMWPE fibres produced thereof are useful in a variety of applications, the invention relating in particular to ropes, medical devices, composite articles and ballistic-resistant articles containing said UHMWPE fibres.
US09005751B2 Fibers comprising nanodiamond and platinum nanocolloid, and bedding formed thereby
Fibers containing nano-sized diamond and platinum nanocolloid, and bedding formed thereby.
US09005749B2 Intermediate transfer members
An intermediate transfer member that includes a mixture of superhydrophobic dimpled polyimide particles, an optional conductive component, and an optional polymer.
US09005748B1 Coating containing borosilicate flake glass
A coating material containing borosilicate flake glass is disclosed, together with methods for the preparation and use thereof.
US09005741B1 Multi-spectral cloak system
Fabric has a printed pattern with a base color and at least one design color. The design color has a plurality of irregular, non-repeating spots. The printed pattern is adapted to abate identification of the fabric by a light responsive device. The fabric also includes metal extending throughout. The metal is adapted to abate identification of the fabric by an infrared, heat responsive device.
US09005739B2 Laminated articles and their production
A laminated article comprises a substrate having opposite major surfaces, and a multi-layer lamination composition comprising (i) a base layer and (ii) an adhesion layer bonded to at least one surface of the base layer. The adhesion layer (ii) comprises a propylene copolymer which comprises units derived from propylene and from about 3 to about 25 wt % of units derived from ethylene and/or a C4 to C8 alpha-olefin and which has a melting temperature less than about 105° C. and a heat of fusion less than about 75 J/g. The lamination composition is thermally laminated to the substrate such that said adhesion layer (ii) is bonded to at least one major surface of said substrate.
US09005735B2 Composite of metal and resin and manufacturing method thereof
A composite of metal and resin includes a metal piece and a resin piece. The metal piece includes a surface. Micropores are formed on the surface. The micropores have inlet diameters smaller than bottom diameters thereof. The resin piece is partially inserted into the micropores to combine with the metal piece.
US09005734B2 Articles of commerce having three-dimensional sheets
A sanitary article is disclosed. The sanitary article comprises a disposable, macroscopically three-dimensional sheet. The sheet has a first surface and a second surface. One of the surfaces comprises a macroscopic three-dimensional texture. The macroscopic three-dimensional texture comprises peaks and valleys such that the textured surface may have an Average Peak to Peak Distance in the range of about 3 mm to about 16 mm, an Average Height Differential in the range of 1 mm to about 3 mm, and a Surface Topography Index in the range of about 0.1 to about 5. The sanitary article may comprise a surfactant on the sheet.
US09005732B2 Friction-tolerant disks made of fiber-reinforced ceramic
A composition comprising polymer-bound fiber tows containing carbon fibers, the polymer-bound fiber tows having an average length of 3 mm to 50 mm measured in the fiber direction, and an average bundle thickness of 0.1 mm to 10 mm measured perpendicular to the fiber direction, and in which at least 75% of all polymer-bound fiber tows have a length that is at least 90% and not greater than 110% of the average length combined with a carbon-ceramic material.
US09005731B2 Composite plate and method of draining a composite plate
The present invention concerns a composite plate (1) comprising a first cover layer (3), a second cover layer (5), and a core layer (7) arranged between the first and the second cover layers (3, 5) and having a plurality of cells (9) which are at least partially open towards the first cover layer (3) and which are separated from each other by walls as well as a method of draining such a composite plate (1). In order to provide such a composite plate (1) in which improved resistance to ingress of liquid or formation of liquid accumulations is guaranteed in a simple and continual fashion it is proposed that a draining layer (13) is provided in the first cover layer (3), wherein the cells (9) are at least partially covered by the draining layer (13).
US09005725B1 Transparent ink-jet recording films, compositions, and methods
Transparent ink-jet recording films, compositions, and methods are disclosed. Such films do not exhibit excessive ink drying times. These films exhibit high maximum optical densities and have low haze values. These films are useful for medical imaging.
US09005721B2 Liquid-crystal display
Disclosed are liquid-crystal (LC) media for use in LC displays of the PS (polymer stabilized) or PSA (polymer sustained alignment) type which contain a liquid-crystal (LC) mixture that contains one or more compounds of formula I
US09005717B2 Methods for making environmental barrier coatings using sintering aids
Methods for making an environmental barrier coating using a sintering aid involving: applying a bond coat layer to the ceramic component; combining at least an organic solvent and a primary transition material selected from a rare earth disilicate or a doped rare earth disilicate to produce a transition layer slurry; applying at least the transition layer slurry, and optionally an outer layer slurry and/or a compliant layer slurry to the component; and sintering the component to produce the environmental barrier coating. The sintering step causes a reaction between a slurry sintering aid and constituents of at least one of the transition, outer and compliant layers to form a secondary material and reduce porosity in the coating.
US09005716B2 Method for making solvent based environmental barrier coatings using sintering aids
Methods for making an environmental barrier coating using a sintering aid including combining at least an organic solvent and a primary transition material to produce a transition layer slurry; applying a bond coat layer and then the transition layer slurry to the component; drying the applied transition layer slurry; infiltrating into the dried transition layer slurry a sol-gel solution containing an aqueous or organic solvent solution of, respectively, a water-soluble or solvent-soluble salt sintering aid; and sintering the infiltrated transition layer slurry to produce the environmental barrier coating having at least the bond coat layer and a transition layer; wherein during sintering a reaction between the primary transition material and the sintering aid results in the transition layer having a porosity of from 0% to about 15% by volume of the transition layer.
US09005715B2 Method for the surface treatment of large parts, gripper of parts suitable for implementing such a method, use of said gripper and treatment cubicle
A system and method of painting parts of large dimensions that present a certain amount of flexibility that makes their shape geometrically unstable in the event of being moved. The surface of a part is moved in front of a paint spray device by an arm of a robot, while the spray device remains stationary relative to the robot and while the part is being deformed. Other elements include a gripper for gripping parts of large dimensions, the gripper being adapted to implement the method; an installation; and a booth for performing surface treatment of parts.
US09005712B2 Method for forming a multilayer coating
The present disclosure is directed to a method of applying at least one layer of a waterborne primer composition, at least one layer of a waterborne basecoat composition and at least one layer of a clearcoat composition to a substrate followed by a heating step which simultaneously cures the applied layers of coating composition.
US09005711B2 Method for forming a lubricating film
A method of forming a lubricating film on a surface, comprising applying to a surface a multiphasic composition comprising at least one (per)fluoropolyether (PFPE) lubricant, water and from 0.1 to 3% by weight of water of at least one thickening agent, said multiphasic composition having a viscosity, when measured at 21° C. at a shear rate of 1 sec−1 of at least 10 Pa×sec so as to form a layer, and drying said layer to form a lubricating film. The Applicant has found that by the use of the multiphasic composition as above detailed it is advantageously possible to convey to surface to be lubricated the PFPE lubricant by using application techniques (doctor blade, metering rod, . . . ) as those suitable for solid-like greases, while the actual conveyed lubricant behaves in lubrication as an oil, avoiding the use of fluorinated solvents.
US09005710B2 Footwear assembly method with 3D printing
Methods and systems are disclosed for apparel assembly using three-dimensional printing directly onto fabric apparel materials. Disclosed is a method and system for direct three-dimensional printing and assembly of an article of apparel, including designing a three-dimensional pattern for printing, positioning at least a portion of the article on a tray in a three-dimensional printing system, the portion being positioned substantially flat on the tray, printing a three-dimensional material directly onto the article using the designed pattern, curing the printed material, and removing the article from the three-dimensional printing system.
US09005704B2 Methods for depositing films comprising cobalt and cobalt nitrides
Cobalt-containing films, as well as methods for providing the cobalt-containing films. Certain methods pertain to exposing a substrate surface to a precursor and a co-reactant to provide a cobalt-containing film, the first precursor having a structure represented by: wherein each R is independently C1-C6 substituted or un-substituted alkanes, branched or un-branched alkanes, substituted or un-substituted alkenes, branched or un-branched alkenes, substituted or un-substituted alkynes, branched or un-branched alkynes or substituted or un-substituted aromatics, L is a coordinating ligand comprising a Lewis base.
US09005702B2 Re-usable high-temperature resistant softgoods for aerospace applications
High-temperature fabrics with a coatings to provide oxidation protection at high temperatures, and capable of being formed into a variety of softgoods parts, and methods for their manufacture are disclosed.
US09005699B2 Method for manufacturing magnetic recording medium
A method for manufacturing a magnetic recording medium includes the steps of (a) forming a perpendicular magnetic recording layer and (b) applying an ion beam to regions between tracks of the perpendicular magnetic recording layer so as to form separation regions for magnetically separating the tracks from each other. In the step (a), a continuous film layer composed of a multilayer film is formed, and CoB layers and Pd layers are laminated in the multilayer film. In the step (b), the CoB layers and the Pd layers are melted by the ion beam so as to form an alloy of metals contained in the CoB layers and the Pd layers to thereby form the separation regions.
US09005696B2 Medical device for bone implant and method for producing such a device
A bone implantable medical device made from a biocompatible material, preferably comprising titania or zirconia, has at least a portion of its surface modified to facilitate improved integration with bone. The implantable device may incorporate a surface infused with osteoinductive agent and/or may incorporate holes loaded with a therapeutic agent. The infused surface and/or the holes may be patterned to determine the distribution of and amount of osteoinductive agent and/or therapeutic agent incorporated. The rate of release or elution profile of the therapeutic agent may be controlled. Methods for producing such a bone implantable medical device are also disclosed and employ the use of ion beam irradiation, preferably gas cluster ion beam irradiation for improving bone integration.
US09005695B2 Composite stent with inner and outer stent elements and method of using the same
An endoprosthesis comprising a stent, a cover fully covering the stent wherein the cover has variable porosity in the radial direction; and an adhesion layer connecting the stent to the cover. Another aspect of the invention is a method of implanting an endoprosthesis which includes a stent, providing a cover with variable porosity in the radial direction, connecting the stent to the cover with an adhesion layer to form a covered stent, and implanting the covered stent within a body lumen of a patient.
US09005693B2 Artificial fingerprint material, process of application, and method of evaluating fingerprint resistance qualities of a surface
An artificial fingerprinting solution that includes a heated blend of glyceryl trioleate and artificial sebum configured to approximate the fingerprint oil of a human. The artificial fingerprinting solution may also be included in a kit that also includes an artificial fingerprint stamp that has an artificial fingerprint transfer member that imitates a human fingerprint and is capable of receiving and holding at least a portion of the artificial fingerprint solution when the artificial fingerprinting transfer member contacts the artificial fingerprint solution.
US09005692B2 Distillation process
A process of reducing the agricultural residue (AR) content of a citrus oil, comprising (a) vacuum batch-distilling an AR-containing cold-pressed citrus oil to give a low-AR distillate and a high-AR residue; (b) subjecting the high-AR residue from (a) to thin film evaporation to give a high-AR distillate and a low-AR residue; (c) subjecting the high-AR distillate from (b) to a further batch distillation to give a redistilled low-AR distillate and a waste high-AR redistilled residue; and (d) combining the distillate of (a), the residue of (b) and the redistilled distillate of (c) to give a low-AR citrus oil. The oil thus produced has not only a reduced content of ARs such as insecticides, fungicides, herbicides and miticides, but it also contains most or even all of the desirable citrus components substantially eliminated by conventional distillation processes.
US09005691B2 Method for producing a confectionery semi-processed product, such as a chocolate-type product
A method of producing a semifinished confectionary product, such as chocolate or similar, using at least one centrifugal unit for simultaneously grinding and mixing at least some of the ingredients of the semifinished product, and which includes an elongated processing chamber with a substantially horizontal axis, at least one inlet for the ingredients to be processed and one outlet for the processed ingredients, and a powered shaft fitted inside the processing chamber, coaxially with the axis, and fitted with a succession of radial appendixes arranged between the inlet and the outlet; the method including the steps of loading at least a first ingredient of the semifinished product through the inlet; grinding the first ingredient inside the grinding and mixing unit by rotating the shaft at a first speed; loading at least a second ingredient through the inlet, after grinding; rotating the shaft at a second speed to grind and mix the ingredients to form a mixture of the same grain size as the semifinished product; loading at least a third ingredient through the inlet; mixing the third ingredient with the previously ground mixture to form a further mixture; bringing the further mixture to a given temperature to obtain the semifinished product; and transferring the semifinished product to a storage or packaging station.
US09005690B2 Aerated products with reduced creaming
A flowable aerated composition is provided which comprises hydrophobin and a yield stress agent, the composition having a continuous phase viscosity, measured at a shear rate of 10 s−1, of from 0.01 to 2000 Pa s, and a continuous phase apparent yield stress of at least 4 Pa.
US09005689B2 Process for the preparation of a flavor active composition
The invention concerns a flavor active composition obtainable by a multi-step reaction comprising a first reaction between an amino compound and a carbonyl compound to obtain a first intermediate reaction mixture, a second reaction with a second amino compound alone or in combination with a carbonyl compound to obtain a second intermediate reaction mixture, further separate reactions with another amino compound alone or in combination with a carbonyl compound to obtain further intermediate reaction mixture, further separate reactions with compounds from other chemical classes such as alcohols, phenolic compounds, epoxydes or organic acids and combinations thereof leading to suitable intermediates, a last reaction comprising a mixture of all the preceding intermediate mixtures alone or in combination with amino and/or carbonyl compounds to obtain the final flavor composition.
US09005680B2 Oral compositions comprising propolis
Oral compositions are provided that comprise a propolis extract; a halogenated diphenyl ether non-ionic antibacterial agent; an anionic polymeric copolymer of methyl vinyl ether and maleic anhydride; and a source of fluoride ions. The oral composition can be in a form of a mouth rinse, a dentifrice, a confectionary, a medicament, or a film. Methods of making and using the oral compositions are also provided.
US09005679B2 Use of extracts of Capraria biflora in the prevention and/or treatment of senile cataracts
The invention provides methods for treating and/or preventing the recurrence of a senile cataract, and/or for inhibiting the development of a senile cataract and/or an incipient senile cataract, in a human or animal subject. The invention further provides nutraceutical compositions suited for the same, derived from an extract of the plant Capraria biflora. The compositions comprise the extract in a therapeutically sufficient amount for the treatment and/or prophylaxis of a senile cataract in a human and/or animal subject.
US09005671B2 Concentrated aqueous bromine solutions and their preparation
This invention provides concentrated aqueous biocidal solutions formed from bromine chloride, sodium hydroxide, and sulfamic acid. The weight ratio of bromine chloride:sodium hydroxide:sulfamic acid used in forming the concentrated solution is such that for every 10.5 to 11.5 parts by weight of bromine chloride used, 15.3 to 17.5 parts by weight of sodium hydroxide and 11.0 to 12.5 parts by weight of sulfamic acid are used, the biocidal solution containing at least about 100,000 ppm (wt/wt) of active bromine based on the total weight of the solution.
US09005665B2 Compositions and methods for treating and preventing porcine reproductive and respiratory syndrome
Disclosed herein are methods and compositions for treating or preventing Porcine reproductive and respiratory syndrome (PRRS) infection in a subject.
US09005663B2 Methods for producing silver nanoparticles
An exemplary embodiment of the invention is a method for making silver nanoparticles, and includes steps of reacting a silver salt with a phosphene amino acid to make silver nanoparticles. Exemplary phosphene amino acids include trimers, with a particular example being a trimeric amino acid conjugate containing one phosphene group. In an exemplary method of the invention, the silver nanoparticles may be produced in timer periods of less than about 30 minutes, and at temperatures of less than about 40° C. Other methods of the invention are directed to methods for stabilizing silver nanoparticles.
US09005662B2 Biocompatible polyelectrolyte complexes and methods of use
An article comprising a polyelectrolyte complex comprising an interpenetrating network of at least one predominantly positively charged polyelectrolyte polymer and at least one predominantly negatively charged polyelectrolyte polymer, the polyelectrolyte complex further comprising a plurality of closed-shell pores, the plurality of pores having at least one average transverse dimension between about 100 nanometer and about 1000 micrometers.
US09005657B2 In situ mixing and application of hydrocolloid systems for pre- and post harvest use on agricultural crops
In-situ methods of applying ethylene response manipulation formulations are disclosed. The formulations comprise at least one ethylene response manipulation agent which is at least partially encapsulated, a polyol liquid medium, or a hydrogel medium, or a combination of polyol and hydrogel medium. A preferred ethylene response manipulation agent is 1-methylcyclopropene.
US09005656B2 Activated nitric oxide donors and methods of making and using thereof
Described herein are compositions useful in anticancer treatment and prevention. The compositions are composed of (a) an O2-aryl substituted diazeniumdiolate and (b) an amphiphile, wherein the amount of amphiphile is sufficient to produce a liposome or micelle. The compositions described herein provide numerous advantages such as increased solubility and stability of the O2-aryl substituted diazeniumdiolate in vivo. The compositions also do not induce hypotension. Methods for using the compositions in anticancer treatment and prevention are also described herein.
US09005653B2 Transdermal delivery of hormones with low concentration of penetration enhancers
The present invention relates to a patch comprising a drug-containing layer with low content of hormones, such as gestodene, and optionally an estrogen (e.g. ethinyl estradiol). Upon administering the patch to a woman, plasma levels of at least 1.0 ng/ml of Gestodene is achieved at steady state conditions without the need of incorporating penetration enhancers or permeation enhancers in the drug-containing layer. Satisfactorily plasma levels of the hormones is also achieved throughout a period of at least 1 week, making the patch applicable for being used in female contraception with the concept of administering the patch ones weekly.
US09005652B2 Chewable tablet containing phenylephrine
A chewable pharmaceutical composition comprising phenylephrine, artificial sweetener, and a substantially aldehyde-free matrix is provided. The composition has phenylephrine stability suitable for a typical commercial product with a two year shelf life. A method of manufacture of the composition and a method of use are also provided.
US09005649B2 Methods for making controlled delivery devices having zero order kinetics
A method of making an injectable or implantable active agent delivery device capable of delivering a diagnostic, therapeutic, and/or prophylactic agent to a desired targeted site having orifice(s) on the surface is disclosed herein providing unidirectional release of the agent at a controlled desirable rate. The agent may include, but is not limited to, drugs, proteins, peptides, biomarkers, bioanalytes, and/or genetic material. The technology of the invention is based on parallel processing to fabricate micro-holes on tubes employing photo-lithography and reactive ion etching techniques and also incorporates a simple molding method to form the micro-holes on flexible polymer tubes, including bio-degradable tubes. The parallel processing method of the instant invention is fast, economical and well suited for mass production. The developed device, due to its composite structure, has the ability to combine several release mechanisms, leading to zero-order release kinetics for most of the time.
US09005642B2 Intumescent fire retardant paint with insecticide
Intumescent fire retardant paint includes an insecticide. The paint can be a latex. Another active agent, for example, a mold inhibitor, may be included. The insecticide may be, for example, a termiticide.
US09005640B2 Fabric and fibre conditioning additives
A fabric, fiber, hair or skin conditioning additive for use in a liquid cleaning product is encapsulated within a shell comprising a silicon-containing polymer network.
US09005636B2 Pharmaceutical composition comprising metformin and rosuvastatin
This invention relates to oral pharmaceutical compositions of metformin and rosuvastatin. In detail, a pharmaceutical composition comprising metformin, rosuvastatin, sustained release carriers and/or excipients reduces the side effects caused by statins and enhances safety, patients' convenience and compliance with its one-per-day dosage. In addition, regulation of an early effective blood concentration of the drug and maintenance of the drug's concentration at a steady level in vivo by a controlled-release can be advantageously used as a pharmaceutical composition for preventing and treating hyperlipidemia.
US09005632B2 Compositions, methods and uses for poxvirus elements in vaccine constructs against influenza virus subtypes or strains
Embodiments of the present invention generally disclose methods, compositions and uses for generating and expressing poxvirus constructs. In some embodiments, constructs may contain an influenza virus gene segment. In certain embodiments, methods generally relate to making and using compositions of constructs including, but not limited to, poxvirus vaccine compositions having two or more influenza gene segments. In other embodiments, vaccine compositions are reported of use in a subject.
US09005629B2 Method for treating cancer with an antibody to CD223 protein
Mammals with cancer are treated with an antibody which specifically binds to CD223 protein and inhibits negative T cell regulatory function of CD223. The mammal may be a human. The antibody may be a monoclonal antibody. The amount of the antibody administered may be sufficient to enhance an immune T cell response to the cancer.
US09005628B2 Biotherapy for pain
The present invention is directed to analgesic Clostridial neurotoxin derivatives comprising polypeptides having a long-lasting SNARE protein-selective endopeptidase activity. These derivatives selectively bind to and are internalized by non-neuronal cells secreting cytokines or sensory neurons in preference to motor neurons or autonomic neurons. The invention is also directed to nucleic acid constructs encoding such polypeptides, and methods of making such derivatives and nucleic acid constructs, and methods of treating pain, such as chronic pain, by administering such derivatives to a patient suffering from, or at risk of suffering from such pain.
US09005624B2 Binding molecules capable of neutralizing rabies virus and uses thereof
Provided are binding molecules that specifically bind to rabies virus and are capable of neutralizing the virus. Further provided are nucleic acid molecules encoding the binding molecules, compositions comprising the binding molecules and methods of identifying or producing the binding molecules. The binding molecules can be used in the diagnosis, prophylaxis and/or treatment of a condition resulting from rabies virus. In certain embodiments, they can be used in the post-exposure prophylaxis of rabies.
US09005621B2 Human binding molecules capable of binding to and neutralizing influenza B viruses and uses thereof
Described are binding molecules, such as human monoclonal antibodies, that bind to hemagglutinin of influenza B viruses, and have a broad neutralizing activity against such influenza viruses. These binding molecules do not bind to hemagglutinin of influenza A viruses. Further provided are nucleic acid molecules encoding the binding molecules, and compositions comprising the binding molecules. The binding molecules can be used in the diagnosis of, prophylaxis against, and/or treatment of influenza B virus infections.
US09005620B2 Compounds
Binding members, e.g. human antibody molecules, which bind interleukin-6 (IL-6) and neutralize its biological effects. Use of binding members for IL-6 in medical treatment e.g. for treating inflammatory diseases and tumors associated with IL-6.
US09005615B2 Methods for treatment of inflammatory diseases
The present invention provides methods of treating inflammatory diseases in a subject comprising administering to the subject a therapeutically effective amount of an agent that inhibits pigment epithelium-derived factor (PEDF) and methods of screening for agents that inhibit PEDF.
US09005614B2 PRLR-specific antibody and uses thereof
PRLR-specific antibodies are provided, along with pharmaceutical compositions containing such antibody, kits containing a pharmaceutical composition, and methods of preventing and treating cancer.
US09005607B2 Stem cell culture method
Methods for culturing pluripotent stem cells on fiber scaffolds are provided which result in the expansion of the number of stem cells without loss of pluripotency. Cells obtained by such methods, implants containing such cells and medical methods using such cells are also disclosed.
US09005602B2 Modified vaccinia virus strains for use in diagnostic and therapeutic methods
Modified viruses and methods for preparing the modified viruses are provided. Vaccines that contain the viruses are provided. The viruses can be used in methods of treatment of diseases, such as proliferative and inflammatory disorders, including cancer, and as anti-tumor and/or antiangiogenic agents. The viruses also can be used in diagnostic methods.
US09005601B2 Methods and compositions including spore-forming bacteria for increasing the health of animals
Methods, compositions and bacterial isolates for improving the gastrointestinal health of animals and in particular of poultry are provided herein. The methods include administering an endospore-forming bacteria to an animal. The bacteria are selected for the ability to reduce the growth and presence of bacterial pathogens, such as Salmonella, Clostridium, and Campylobacter, in the gastrointestinal tract of the animal. The bacteria are also selected for the ability to improve at least one production parameter in the animal.
US09005598B2 Conjugated proteins and peptides
Novel compounds of the general formula (I): in which X represents a polymer; Q represents a linking group; W represents an electron-withdrawing moiety or a moiety preparable by reduction of an electron-withdrawing moiety; each of R1 and R2 independently represents a hydrogen atom or a C1-4alkyl group; and either Z1 represents a protein or a peptide linked to CR2 via a nucleophilic moiety, and Z2 represents a molecule linked to CR2 via a nucleophilic moiety, or Z1 and Z2 together represent a single group derived from a protein or peptide linked to CR via two nucleophilic moieties.
US09005597B2 Formulation for treatment of vaginal dryness
The present invention is directed to a composition for treating vaginal dryness and lack of lubrication comprising: a poloxamer component; a phospholipid component; an optional oil component; and a non-aqueous carrier; wherein the composition is substantially anhydrous. In another aspect, the present invention is directed to a method of treating vaginal dryness comprising the step of administering to a patient suffering from vaginal dryness the above composition.
US09005596B2 Bi-functional co-polymer use for ophthalmic and other topical and local applications
The invention contemplates a copolymer which is a graft or block copolymer useful to change wettability and surface characteristics of biological surfaces. Methods for use of these formulations and coatings to change wettability and sterically stabilize, and lubricate biological surfaces in a subject, for example, in the treatment of dry eye syndrome, and to prevent adherence of unwanted proteins, for example in the treatment of contact lens intolerance, are provided.
US09005595B2 Chinese medicine hair-blackening preparation and formula and preparation method therefor
A Chinese medicine hair-blackening preparation and formula and a preparation method therefor, wherein the preparation comprises ginger, astragalus mongholicus, polygonum multiflorum, black sesame, angelica sinensis, fructus lycii, ligusticum wallichii, salvia miltiorrhizae, chrysanthemum indicum, red dates, black soya bean, walnuts, cortex mori radicis, fructus liqustri lucidi, eclipta alba, mulberry fruit, fat extract of silkie, fat extract of duck, 65% ethanol solution and 40% ethanol solution; the preparation is prepared by using techniques of mixing, grinding, soaking and extraction to produce an ointment; the preparation is suitable for all hair and scalp types, and when it is used after hair wash, it produces no allergic reactions or toxic side-effects, thereby allowing the medically active elements to penetrate quickly into the skin and to be absorbed by the skin to achieve quickly visible hair blackening effect.
US09005594B2 Method for lightening human keratin fibers using at least one anhydrous composition, at least one organic amine, and at least one oxidizing agent, and device for use thereof
A novel process for lightening human keratin fibers comprising applying to the fibers at least one anhydrous composition (A) comprising at least one fatty substance and at least one surfactant, at least one composition (B) comprising at least one organic amine having a pKb less than 12, and at least one composition (C) comprising at least one oxidizing agent and leaving the compositions on the fibers for a period of time sufficient to lighten the fibers; and a multi-compartment device or kit, wherein at least one first compartment comprises the at least one anhydrous composition (A), at least one second compartment comprises the at least one composition (B), and at least one third compartment comprises the at least one composition (C).
US09005592B2 Compositions having HASE rheology modifiers
A monomer compound that contains at least one polymerizable functional group per molecule, and at least one bicycloheptyl-, bicycloheptenyl-, or branched (C5-C42)alkyl-polyether radical per molecule, wherein the bicycloheptyl- or bicycloheptenyl-polyether radical may optionally be substituted on one or more of the ring carbon atoms by one or two (C1-C6)alkyl groups per ring carbon atom is useful in making polymers, particularly pH responsive polymers.
US09005587B2 Anti-bacterial and mineralizing calcium phosphate compositions
The present invention provides compositions including saturated calcium phosphate (sCaP) solutions, that may be prepared from mixtures of calcium deficient apatite and one or more of sodium fluoride and zinc chloride, or F or Zn ions. The solutions may be prepared from mixtures of calcium compounds and one or more of sodium or potassium phosphates, sodium or potassium fluoride and zinc salts with, for instance, either phosphoric or hydrochloric acids. Such compositions may be useful for increasing occlusion of dentin tubules, decreasing bacterial attachment to dentin tubules, decreasing bacterial growth or colonization on tooth surfaces such as enamel and dentin surfaces including on dentin tubules, increasing resistance to acid dissolution, inhibiting dental caries formation and progression and tooth decay and inhibiting development of tooth hypersensitivity.
US09005586B2 Dentifrice containing zinc ions and polyphosphate ions
The invention includes a dentifrice composition that comprises a zinc ion source, a polyphosphate ion source, an anethole and a silica. The silica has a mean particle size of about 5 to about 12 microns, an Einlehner hardness of about 1 to about 20, and an oil absorption of about 40 to less than about 100 cc/100 g. The composition contains zinc ions and polyphosphate ions in a weight ratio of about 0.1:1 to about 10:1 and has a RDA value of about 100 to about 200 and a PCR value of about 75 to about 110. Related methods are also included.
US09005583B2 Chain-end functionalized poly(ethykene oxide) and process for the preparation of a nano-sized transition metal or metal salt using the same
There is provided a novel chain-end functionalized PEO of formulas (I) to (IV) prepared via living anionic polymerization and chain-end functionalization, as well as a simple method of preparing nano-sized transition metal or metal salt particles using the same, which can be readily stabilized even in an aqueous medium. The water-soluble PEO-based polymers having various functional groups (including a drug group such as vitamin and anti-cancer agent) and the process of preparing nano-sized transition metal or metal salt particles using the same can be advantageously used in the development of new materials for drug delivering system and imaging, e.g., a contrast agent and an anti-cancer agent simultaneously.
US09005582B2 Hyperthermia therapeutic agent delivery system
A medical delivery system that enables the delivery of therapeutic agents to malignant tissue utilizing delivery agents and heating of the delivery agents thereby causing the release of the therapeutic agents within the tumor is disclosed. The therapeutic agents may be chemotherapy agents, radiation therapy agents, and other appropriate materials. The magnetic nanoparticles encapsulated by the therapeutic agents in a biocompatible coating may be delivered to tumor sites utilizing attenuated strains of bacteria that seek and reside at tumor sites. An alternating magnetic field device with a prescribed frequency range may be used to induce heating of the magnetic nanoparticles in the patient thereby melting the coating and releasing the therapeutic agents within the tumor.
US09005579B2 Methods and compositions for enhanced immunological therapy and targeting of gram-positive bacteria
The present invention relates to methods and compositions for use in modulating, including inhibiting the growth and/or reducing the virulence of gram-positive bacteria. The present invention provides methods and compositions for disrupting the cell wall and/or cell membrane in gram-positive bacteria such that cell wall or cell membrane target(s) are rendered exposed or accessible and sensitive to a modulation thereof. Methods for modulation of one or more gram-positive bacterial cell wall or cell membrane targets in a gram-positive bacteria are provided comprising disrupting the cell wall such that the cell wall or cell membrane target, which is particularly a sortase, is rendered exposed or accessible and sensitive to a modifying, modulating or binding agent, which is particularly an antibody or fragment thereof, wherein the cell wall or cell membrane target is inaccessible or relatively insensitive to the modifying, modulating or binding agent in the absence of cell wall disruption.
US09005577B2 Substrate based PET imaging agents
The present application is directed to radiolabeled imaging agents comprising a radiolabel, and a substrate, pharmaceutical compositions comprising radiolabeled imaging agents, and methods of using the radiolabeled imaging agents. The present application is further directed to methods of preparing the radiolabeled imaging agent. Such imaging agents can used in imaging studies, such as Positron Emitting Tomography (PET) or Single Photon Emission Computed Tomography (SPECT).
US09005569B2 Microstructure and manufacturing method therefor
A microstructure that can develop non-conventional and novel physical properties and a method for producing the same are provided. Ethanol is added to a mixture solution produced by adding a surfactant solution to a peroxotitanic acid aqueous solution to produce precipitates, and the precipitates collected from the mixture solution are let dried to produce precursor powders 5. The precursor powders 5 are calcined at a predetermined temperature. Accordingly, a microstructure 2 can be produced which is formed of monophasic Ti4O7 in nano size. The microstructure 2 of monophasic Ti4O7 produced in this fashion can be fine-grained in nano size unlike prior-art crystals.
US09005568B2 Process for production of powder of perovskite compound
The invention provides a process for production of powder of perovskite compound which comprises: the first step for obtaining an aggregate of perovskite compound which comprises at least one A group element selected from the group consisting of Mg, Ca, Sr, Ba and Pb and at least one B group element selected from the group consisting of Ti, Zr, Hf and Sn, and which is represented by the general formula ABO3 wherein A is at least one A group element and B is at least one B group element; and the second step for heating the aggregate of perovskite compound obtained in the first step in a solvent at a temperature in a range from 30° C. to 500° C. whereby disintegrating the aggregate. The process makes it unnecessary to resort to a conventional mechanical crushing means or to make use of impact caused by milling media or airflow, but it makes possible to obtain a powder of perovskite compound which is not contaminated with impurities derived from milling media or chipping particles but has a high purity and a narrow particle size distribution.
US09005567B2 Method for producing isolatable oxide microparticles or hydroxide microparticles
A method for producing isolatable oxide microparticles or hydroxide microparticles using an apparatus that processes a fluid between processing surfaces of processing members that are arranged opposite each other so as to be able to approach to or separate from each other and such that at least one can rotate relative to the other. At least two fluids are mixed and oxide microparticles or hydroxide microparticles are separated, said two fluids including: a fluid containing a microparticle raw material solution comprising a microparticle raw material mixed into a solvent, and a fluid containing a microparticle-separation solution. Immediately thereafter, the following are mixed to obtain isolatable oxide microparticles or hydroxide microparticles: a fluid containing the separated oxide microparticles or hydroxide microparticles; and a fluid containing a microparticle-treatment-substance-containing solution that contains a microparticle-treatment substance that adjusts the dispersibility of the separated oxide microparticles or hydroxide microparticles.
US09005566B2 Staged combustion of sulfureous combustible effluents with recovery of the sulfur in the claus process
A process for advantageously efficiently treating a sulfureous combustible effluent stream by recovering the sulfur in elemental form comprises a step of combustion of the sulfureous combustible effluent stream with an oxidant gas in excess, and then a step of post-combustion of the effluents from the combustion step with an acidic gas. The stream of the post-combustion effluents, free of chemical compounds that are harmful to the efficacy of the Claus catalysts, is treated in a Claus unit, which performs the recovery of the sulfur in elemental form.
US09005565B2 Method and apparatus for forming graphene
A method of forming graphene comprises supplying energy to at least a portion of an organic material monolayer disposed on a substrate. The energy is sufficient to carbonize the at least a portion of the monolayer exposed thereto to form a layer of graphene on the substrate.
US09005564B2 Carbon nanotubes and method for manufacturing the same
Disclosed are carbon nanotubes and a method for manufacturing the same. Advantageously, the method provides a high yield of potato or sphere-shaped non-bundled carbon nanotubes having a bulk density of 80 to 250 kg/m3, an ellipticity of 0.9 to 1.0 and a particle diameter distribution (Dcnt) of 0.5 to 1.0 using a two-component carbon nanotube catalyst comprising a catalyst component and an active component.
US09005563B2 Silicon wafer and method for producing it
Silicon wafers having an oxygen concentration of 5·1017 to 7.5·1017 cm−3 have the following BMD densities after the following thermal processes, carried out alternatively: a BMD density of at most 1·108 cm−3 after a treatment for three hours at 780° C. and subsequently for 16 hours at 1000° C., and a BMD density of at least 1·109 cm−3 after heating of the silicon wafer at a heating rate of 1 K/min from a start temperature of 500° C. to a target temperature of 1000° C. and subsequent holding at 1000° C. for 16 hours. The wafers are prepared by a method of irradiation of a heated wafer with flashlamp which delivers energy which is from 50 to 100% of the energy density necessary for melting the wafer surface.
US09005557B2 Production of high purity lithium compounds directly from lithium containing brines
A process for reducing the amount of magnesium in a lithium-containing brine by adding an aqueous solution of KCl to the brine to precipitate at least some of the magnesium as carnallite salt is disclosed. Lithium salts prepared using this magnesium removal process are also disclosed.
US09005545B2 Method for detecting biomolecules electrically and biochip therefor
The present invention relates to a method for detecting the presence and/or the reaction of a biomolecule by monitoring changes of electrical property accurately according to the biological, biochemical or chemical reaction of the biomolecule, and a biochip provided for this purpose.
US09005542B2 Storage system for storing laboratory objects at low temperatures
The storage arrangement has a chamber. Several Dewar flasks are arranged in the chamber and above them a picking device. The picking device has at least one cassette lift, with which storage cassettes can be removed from above from the Dewar flasks. This arrangement is suitable for storing laboratory objects at very low temperatures.
US09005541B2 Medical sterilization container with gas-exchange filter
A medical sterilization container has a removable container cover, which is provided in a wall area (4) with gas-exchange openings (5), with a filter unit (55) for gas exchange has an interchangeable filter sheet covering the gas-exchange openings (5) on the inside, which is arranged within a ring-shaped circumferential frame element (15) and is held pressably against an inside of the wall area (4) by a pressure washer (36) provided with openings (45). The pressure washer (36) is detachably connected to frame element (15) or the wall area (4) and has a ring groove (48) with a preferably elastic sealing ring (49), which seals the wall area (4) provided with the gas-exchange openings (5) against the frame element (15). To prevent a shifting of and/or damage to the filter sheet during a clamping process, the pressure washer (36) can be pressed against the wall area (4) by a spring washer (35). The spring washer (35) is provided with bayonet connection elements (38) which can be meshed and unmeshed with bayonet catch elements (20) of the frame element (15). The spring washer (35) is rotatable opposite the pressure washer (36) about a common central axis of rotation of the pressure washer (36) and of the spring washer (35).
US09005539B2 Chamber sealing member
A reaction chamber including an upper region for processing a substrate, a lower region for loading a substrate, a susceptor movable within the reaction chamber, a first sealing member positioned on a perimeter of the susceptor, a second sealing member positioned between the upper region and the lower region, wherein the first and second sealing members are selectively engaged with one another to limit communication between the upper region and the lower region.
US09005537B1 Continuous flow, high capacity system for rapidly converting the combination natural gas and coal to liquid fuels
A continuous high capacity system for converting a combination of natural gas and coal into liquid fuel, using a pug for blending less than 200 micron diameter particulate with a plasticizing agent; a sealing auger for forming an agglomerated material and sealing, a cutting device, a vacuum chamber to remove air from the cut material, a second sealing auger for forming a de-aerated agglomerated material and sealing, a second cutting device, a gas injection chamber for impregnating the de-aerated cut material with natural gas, an extruder forming an extrudate, a heating chamber to evolve at least one gas; a pressure sensor and temperature sensors in the heating chamber, a cooling chamber providing controlled pressure and controlled temperature cooling of the evolved gasses, wherein the cooling chamber liquefies sequentially at least 50 percent of the evolved gasses forming a liquid.
US09005533B2 PCM device and catalytic converter
A PCM device (1) is provided for an exhaust system of an internal combustion engine, especially of a motor vehicle. A simplified installation of the PCM device (1), with reduced heat stresses, is achieved through the provision of at least one storage plate (2), which has two plate bodies (3, 4), which follow each other, enclose a storage space (7) filled with heat storage material (18) and have a wave structure (5, 6) each. The wave structure (5) of one plate body (3) extends sloped in relation to the wave structure (6) of the other plate body (4).
US09005530B2 Compressor with an internal disinfecting UV light source
The air compressor has an air intake, a tank, means for pressurizing the air in the tank and an air outlet connected to the tank. High power 365 nm UV LED light sources are mounted within the tank to disinfect the interior tank surface. The light source has a cover for protecting the light source which may take the form of a quartz diverging lens for directing the output of the light source toward the portion of the interior tank surface where fluid tends to accumulate, such as the bottom of the tank. Air flow is directed through the area proximate the light source to remove particles from the light source cover. The effect of this air flow can be amplified by creating turbulence proximate the light sources utilizing a member with an arcuate profile.
US09005529B2 Ion generating apparatus and air purifying apparatus
A housing having a suction port and a discharge port, an impeller 21 and a casing 22 that houses the impeller 21, an air blower 2 housed in the housing, a filter that lets through the air suctioned from the suction port by the air blower 2, and two ion generating sections that generate positive and negative ions are provided. The ion generating section is arranged on a circular-arc guide wall 2a in the casing 22. The positive and negative ions generated by the ion generating section are efficiently included in the air passing through as laminar flow along the circular-arc guide wall 22a.
US09005527B2 Transient decay amperometry biosensors
A biosensor system determines an analyte concentration of a biological sample using an electrochemical process without Cottrell decay. The biosensor system generates an output signal having a transient decay, where the output signal is not inversely proportional to the square root of the time. The transient decay is greater or less than the −0.5 decay constant of a Cottrell decay. The transient decay may result from a relatively short incubation period, relatively small sample reservoir volumes, relatively small distances between electrode surfaces and the lid of the sensor strip, and/or relatively short excitations in relation to the average initial thickness of the reagent layer. The biosensor system determines the analyte concentration from the output signal having a transient decay.
US09005522B2 Silver alloy
A platinum-free silver alloy may include about 0.1% to 0.9% Au, about 83% to 90% Ag, about 2% to 3% Pd, about 3% to 5% Zn, about 2% to 8% Cu, about 0.01% to 0.4% B, about 0.1% to 0.3% Ge, and about 0.01% to 0.03% Ir.
US09005520B2 Steel compositions for special uses
The invention concerns steels having excellent resistance over time, in a corrosive atmosphere due to oxidizing environments such as, for example, fumes or water vapor, under high pressure and/or temperature. The invention concerns a steel composition for special applications, said composition containing, by weight, about 1.8 to 11% of chromium (and preferably between about 2.3 and 10% of chromium), less than 1% of silicon, and between 0.20 and 0.45% of manganese. It has been found that it is possible to adjust the contents of the composition based on a predetermined model, selected to obtain substantially optimal properties with respect to corrosion in specific conditions of high temperature performances. Said model can involve as additive of as residue at least one element selected among molybdenum, tungsten, cobalt, and nickel.
US09005516B2 Manufacturing method of zeolite structure
The manufacturing method includes a mixing step of mixing a plurality of zeolite particles, an inorganic binding material and an organic binder, to prepare a zeolite raw material, a forming step of extruding the zeolite raw material to obtain a formed zeolite article, and a firing step of firing the formed zeolite article to prepare the zeolite structure. The mixing step includes an inorganic binding material containing at least one type of silica sol selected from the group consisting of acid silica sol, silica sol containing silica particles coated with alumina, cationic silica sol, silica sol containing string-like silica particles, and silica sol containing bead-like silica particles. A content ratio of silica particles contained in the silica sol selected from the group is from 10 to 30 mass% with respect to 100 mass% of the zeolite particles.
US09005512B2 Method for forming patterns and method for producing patterned substrates
A resist layer constituted by a resist composition (which may include unavoidable impurities) including a polymerizable compound that includes polyfunctional monomers that become polymers having three dimensional structures by cross linking when polymerized and a polymerization initiating agent which is activated by one of light and an electron beam is formed on a substrate. A surface of a mold having a predetermined pattern of protrusions and recesses is pressed against the resist layer. Light is irradiated onto the resist layer to cure the resist layer. The mold is separated from the resist layer under conditions that the temperature of the resist layer is 40° C. or greater.
US09005510B2 Processes for producing polymer fibers by electrospinning, colloidal dispersions for use therein, and polymer fibers prepared by such processes
Processes for forming polymer fibers, comprising: (a) providing a colloidal dispersion of at least one essentially water-insoluble polymer in an aqueous medium; and (b) electrospinning the colloidal dispersion; polymer fibers prepared by such processes; and colloidal dispersions comprising: at least one essentially water-insoluble polymer in an aqueous medium; and at least 10% by weight of a water-soluble polymer having a solubility in water of at least 0.1% by weight.
US09005509B2 Injection molding flow control apparatus and method
An apparatus for controlling the rate of flow of mold material to a mold cavity, including a valve system in fluid communication with an actuator to drive the actuator at one or more rates of travel, the valve system having a start position, one or more intermediate drive rate positions and a high drive rate position, the start position holding the valve pin in a gate closed position; a controller that instructs the valve system to move from the start position to the one or more intermediate drive rate positions and to remain in the one or more intermediate drive rate positions for one or more corresponding predetermined amounts of time and further drives the valve system to move from the one or more intermediate drive rate positions to the high drive rate position on expiration of the one or more predetermined amounts of time.
US09005506B2 Manufacturing method and manufacturing apparatus of fiber reinforced composite material
A manufacturing method and a manufacturing apparatus of a fiber reinforced composite material are provided, in which the whole fiber-based material is impregnated with a resin and a molding can be performed with high dimensional accuracy. A manufacturing method of a fiber reinforced composite material according to the present invention includes fixing a fiber-based material having a first surface to a first mold to provide an opening for the first surface; setting a second mold having a second surface such that the first surface faces the second surface through a space; filling resin into the space; and relatively moving the second mold and the first mold to bring the second surface closer to the first surface, such that the fiber-based material is impregnated with the resin.
US09005505B2 Identification device and method for manufacturing thereof
Device for identifying articles such as animals, comprising a male part and a female part, which male part comprises an arrow-shaped element and which female part is provided with a passage with a front end and a rear end, wherein the arrow-shaped element can be inserted into the passage along the front end, wherein the passage is provided close to the front end with at least one protruding element, and wherein the passage is partly closed close to the rear end by a closing part, wherein the partly closed passage, including the protruding element, are manufactured integrally from a hard material; method for manufacturing such a device.
US09005502B2 Mold and manufacturing method thereof
The object of the invention is to provide a mold that is capable of high-precision, stable patterning, and improved in terms of handleability as well, and a manufacturing method thereof. The mold of the invention has a pattern-formation surface defined by one surface, wherein the pattern-formation layer has a projection-and-depression structure area for patterning, and a base surface defined by another surface. At least the pattern-formation layer and the base surface each comprise a polydimethylsiloxane layer. Given a low-molecular-weight siloxane of a cyclic structure represented by [—Si(CH3)2O—]k where k is an integer of 3 to 20 inclusive, the polydimethylsiloxane layer positioned on the pattern-formation layer comprises a high-content polydimethylsiloxane layer containing the low-molecular-weight siloxane in a larger amount, and the polydimethylsiloxane layer positioned on the base surface comprises a low-content polydimethylsiloxane layer containing the low-molecular-weight siloxane in a smaller amount.
US09005498B2 Method for manufacturing soundproofing material using polyurethane foam from car seat foam and composition thereof prepared thereby
Disclosed is a method for manufacturing a soundproofing material by finely crushing a discarded car seat, mixing the crushed car seat with polyester fiber, low-melting polyester fiber such as LM PET, polypropylene fiber and hemp, and carding the resulting mixture, and a soundproofing material composition prepared thereby. The disclosed method allows recycling of polyurethane foam of the discarded car seat into a soundproofing material composition having superior appearance quality and soundproofing performance. The disclosed method also prevents generation of excessive static electricity and allows preparation of a soundproofing material with smooth surface.
US09005497B2 Moulding method for rubber blocks using steam
The present invention relates to a method for molding rubber blocks by combining rubber chips and a urethane binder, and more specifically to a molding method for rubber blocks whereby it is possible to improve the processing time and the physical properties of the product by introducing high-temperature steam during molding. The present invention has advantageous effects in that the molding can take place in a short time without affecting the physical properties of the product even in situations involving heavy molded products, and in that there is no risk of ignition due to self-heating even if the finished products are kept stacked.
US09005496B2 Asymmetric membranes
Asymmetric membranes comprising a first asymmetric porous zone including a first porous asymmetry that increases from the first exterior surface through the first porous zone of the bulk, and a second asymmetric porous zone including a second porous asymmetry that increases from the second exterior surface through the second porous zone of the bulk, wherein the first average pore size is larger than the second average pore size, as well as methods of making and using the membranes, are disclosed.
US09005494B2 Preparation of capsules
Prior art processes for producing protein-based capsules (for example, capsules for use in electrophoretic media) tend to be wasteful because they produce many capsules outside the desired size range, which is typically about 20 to 50 μm. Capsule size distribution and yields can be improved by either (a) emulsifying a water-immiscible phase in a preformed coacervate of the protein; or (b) using a limited coalescence process with colloidal alumina as the surface-active particulate material.
US09005486B2 Proton conducting ceramics in membrane separations
Perovskite materials of the general formula SrCeO3 and BaCeO3 are provided having improved conductivity while maintaining an original ratio of chemical constituents, by altering the microstructure of the material. A process of making Pervoskite materials is also provided in which wet chemical techniques are used to fabricate nanocrystalline ceramic materials which have improved grain size and allow lower temperature densification than is obtainable with conventional solid-state reaction processing.
US09005485B2 High performance die attach adhesives (DAAs) nanomaterials for high brightness LED
The present invention relates to a composition for a one-part die attach adhesives material useful for packaging semi-conductors including HB-LED. The composition of the present invention includes a thermal and electrical conductive filler, a polymer matrix and a solvent which form a material with high thermal conductivity, low curing temperature and high self-life temperature. The present invention also relates to a method of preparing said composition by mixing a size-selected and surface-modified filler formulation, a polymer matrix and a non-reactive organic solvent together followed by curing the mixture at a low temperature.
US09005482B2 Paste composition for rear electrode of solar cell and solar cell including the same
A paste composition for a rear electrode of a solar cell according to an embodiment comprises conductive powder including a first powder having a first mean particle diameter, a second powder having a second mean particle diameter larger than the first mean particle diameter, and a third powder having a third mean particle diameter larger than the second mean particle diameter, and an organic vehicle.
US09005477B2 Liquid crystal composition containing polymerizable compound and liquid crystal display element using the same
A liquid crystal composition containing a polymerizable compound according to the present invention is used in a liquid crystal display element in which a liquid crystal alignment capability is provided through polymerization. The liquid crystal composition contains a polymerizable compound that polymerizes without a photopolymerization initiator or with an extremely small amount of photopolymerization initiator. Therefore, the alignment properties after the polymerization become more stable and the display characteristics do not degrade. Thus, the polymerizable compound is suitable as a practical component of the liquid crystal composition. A liquid crystal display element that uses the liquid crystal composition containing a polymerizable compound according to the present invention can be suitably used for VA and IPS liquid crystal display elements.
US09005472B2 Aqueous polishing agent and graft copolymers and their use in a process for polishing patterned and unstructured metal surfaces
An aqueous polishing agent, comprising, as the abrasive, at least one kind of polymer particles (A) finely dispersed in the aqueous phase and having at their surface a plurality of at least one kind of functional groups (a1) capable of interacting with the metals and/or the metal oxides on top of the surfaces to be polished and forming complexes with the said metals and metal cations, the said polymer particles (A) being preparable by the emulsion or suspension polymerization of at least one monomer containing at least one radically polymerizable double bond in the presence of at least one oligomer or polymer containing a plurality of functional groups (a1); graft copolymers preparable by the emulsion or suspension polymerization of at least one monomer containing at least one radically polymerizable double bond in the presence of at least one oligomeric or polymeric aminotriazine-polyamine condensate; and a process for the chemical and mechanical polishing of patterned and unstructured metal surfaces making use of the said aqueous polishing agent.
US09005469B2 Compressor and refrigeration cycle device using same
According to a compressor and a refrigeration cycle device using same of the present invention, a refrigerant and refrigeration oil 103 are sealed in an container 101, the refrigerant is a hydrofluoroolefin having double bond of carbon in its composition or a mixture of hydrofluoroolefin as a base component and hydrofluorocarbon having no double bond, and at least one of benzotriazole, dialkyl dithiophosphoric acid zinc, dialkyl selenium, metal phenate, and organic nitrogen compound is included in the refrigeration oil 103, and it is an object to suppress the decomposition and polymerization of refrigeration oil and a refrigerant, and to secure reliability of the compressor and the refrigeration cycle device.
US09005468B2 Heat-transfer fluids and use thereof in countercurrent heat exchangers
The invention relates to a ternary composition comprising difluoromethane, 3,3,3-trifluoropropene and a hydrocarbon-derived compound containing at least two fluorine atoms and having a boiling point of between −30 and −18° C., which is selected from 1,1-difluoroethane, 2,3,3,3-tetrafluoropropene and 1,3,3,3-tetrafluoropropene. This composition is particularly suitable for use as a heat-transfer fluid in the presence of countercurrent heat exchangers.
US09005466B2 Highly insulative and highly stable piezoelectric single LTGA crystal, method for producing the same, piezoelectric element using said single LTGA crystal, and combustion pressure sensor
In accordance with the present invention, there is provided a method for producing a single LTGA crystal from a polycrystalline starting material prepared from a mixture of La2O3, Ta2O5, Ga2O3, and Al2O3, wherein a mixture having a composition represented by y(La2O3)+(1−x−y−z)(Ta2O5)+z(Ga2O3)+x(Al2O3) (in the formula, 0
US09005460B2 Layer-by-layer removal of graphene
The present invention provides methods of selectively removing one or more graphene layers from a graphene material by: (1) applying a metal to a surface of the graphene material; and (2) applying a hydrogen containing solution to the surface of the graphene material that is associated with the metal. The hydrogen containing solution dissolves the metal along with one or more layers of graphene associated with the metal, thereby removing the layer(s) of graphene from the graphene material. In some embodiments, the hydrogen containing solution is an acidic solution, such as hydrochloric acid. In some embodiments, the metal is zinc. In some embodiments, the methods of the present invention are utilized to selectively remove one or more layers of graphene from one or more targeted sites on the surface of a graphene material.
US09005459B2 Film deposition method and film deposition apparatus
A disclosed film deposition method includes steps of loading plural substrates each of which includes a pattern including a concave part in a reaction chamber in the form of shelves; depositing a silicon oxide film on the plural substrates by supplying a silicon-containing gas and an oxygen-containing gas to the reaction chamber; etching the silicon oxide film deposited on the plural substrates in the step of depositing by supplying a fluorine-containing gas and an ammonia gas to the reaction chamber; and alternately repeating the step of depositing and the step of etching.
US09005458B2 Photonic device structure and method of manufacture
Disclosed method and apparatus embodiments provide a photonic device with optical isolation from a supporting substrate. A generally rectangular cavity in cross section is provided below an element of the photonic device and the element may be formed from a ledge of the supporting substrate which is over the cavity.
US09005455B2 Device and a method for separating a suspension
A device for extracting a liquid phase from a suspension, the device being characterized in that it comprises: a main duct for conveying a flow of said suspension, the duct being of a length that is sufficient to enable a layer of said suspension to develop that is depleted in solid phase; flow disturbance means for disturbing the flow of said suspension, said means being provided in the main duct and being adapted to cause at least one recirculation vortex to form so as to increase locally the thickness of said depleted layer; and liquid extraction means disposed in a region of the device where said suspension is enriched in liquid phase as a result of said recirculation vortex.A method of extracting a liquid phase from a suspension, the method comprising injecting said suspension into such a device at a flow rate suitable for causing at least one recirculation vortex to be formed, and extracting a fraction of said suspension that is enriched in liquid as a result of said vortex.
US09005454B2 Methods and compositions for treating water-containing systems
Methods and compositions for improving water quality by reducing chlorine demand, decreasing disinfection by-products and controlling deposits in water systems include adding low concentrations of supplemental oxidants, for example, RE-Ox® to the systems.
US09005451B2 Method and device for treating an effluent
Method and device for treating a liquid effluent, in which this effluent enters a vessel. An intermediate level of liquid in the vessel is detected; an influx of a dilution liquid into the vessel is instigated; a high level of liquid in the vessel is detected; the influx of dilution liquid is stopped and a discharge of the fluid is instigated; a low level of liquid in the vessel is detected; the discharge of the liquid is stopped; and, while it is being discharged, the discharged liquid is exposed to light radiation in at least one treatment channel.
US09005449B2 Use of moss to reduce disinfection by-products in water treated with disinfectants
A method of reducing disinfection by-products in water treated with disinfectants including contacting the water with an amount of a non-decomposed moss effective to reduce the level of disinfection by-products. A method of determining the effectiveness of a first method of reducing disinfection by-products in water treated with disinfectants, the first method including contacting the water with an amount of a non-decomposed moss effective to reduce the level of disinfection by-products, the method including determining the effectiveness of the first method by measuring the level of the disinfection by-products in water treated with disinfectants and contacted with the amount of non-decomposed moss.
US09005447B2 Purification procedure for the preparation of the radioactive tracer 3′-deoxy-3′-[18F] fluorothymidine ([18F]FLT)
A procedure for the preparation of the radioactive tracer 3′-deoxy-3′-[18F]fluorothymidine ([18F]FLT) comprises the following steps: a) preparation of anhydrous [18F]F-fluoride; b) labelling of a precursor, for example 3-N-Boc-1-[5′-O-(4,4′-dimethoxytrityl)-3′-O-nitrophenylsulfonyl-2′-deoxy-β-D-lyxofuranosyl]thymidine; c) hydrolysis of the mixture obtained by means of the previous steps; d) purification of the mixture to obtain the radioactive tracer [18F]FLT. In this procedure steps a), b) and c) are carried out by means of known methods. In step d) the mixture obtained after step c) is purified by means of the passage through a ventilated filter and one or more cartridges of the cationic exchange type (e.g. a Chromafix PS-H+), one or more cartridges of the reversed phase type, and finally a passage through cartridges either of the alumina N type, or diol cartridges, or anionic exchange cartridges or a combination thereof. Furthermore, the mixture which is present in the cartridges is eluted with H2O for injection, whereby the resulting product is forwarded to a container or ampoule for the collection of [18F]FLT.
US09005445B2 Method of testing integrity of microporous membrane
The present invention provides a method of testing the integrity of a microporous membrane using a colloid solution containing metal particles or metal compound particles that can accurately determine the integrity of a virus removal membrane formed of hydrophilized synthetic polymer that has been subjected to protein solution filtration, and to provide a method of producing the colloid solution. The colloid solution comprises a solvent and metal particles dispersed in the solvent, and the solvent comprises components (A) and (B), (A) and (C), or (A), (B), and (C), wherein the component (A) is an anionic polymer having a sulfonic acid group, the component (B) is at least one nonionic surfactant selected from the group consisting of a nonionic surfactant having a polycyclic structure in a hydrophobic moiety and a polyoxyethylene sorbitan fatty acid ester, and the component (C) is a water-soluble polymer having a pyrrolidone group.
US09005444B2 Separation of rebaudioside A from stevia glycosides using chromatography
Disclosed are methods for the chromatographic separation of rebaudioside A from stevioside in glycoside solutions that are derived from stevia. The chromatographic separation may be an adsorb/desorb type of chromatographic separation or a fractionation type of chromatographic separation.
US09005437B2 Appliances for the alkalizing of water
The invention is directed to point of use devices and appliances for alkalizing water that is to be ingested. The devices comprise straws, carafes, countertop units, water bottle units, and any other devices that will treat the water at the point of use. The water will flow through the point of use devices or appliances longitudinally or radially. The point of use device or appliance will contain an alkalizing formulation that will increase the pH of the water to preferably above about 8. The amount of water that can be treated will depend on the amount of alkalizing formulation used and the size and capacity of the device or appliance for the alkalizing formulation. The alkalizing formulation will supply to the water being treated one or more of potassium, calcium, and magnesium ions. The water prior to contacting the treatment compound can be filtered through a purification formulation to remove particulates, heavy metals, and various organic compounds. The purification formulation can be a form of activated carbon.
US09005434B2 Water filter
A water filter including a housing, at least one cylindrical filter component disposed within the housing, an inflow pipe extending through, and parallel to a longitudinal axis of, the at least one cylindrical filter component, the inflow pipe including a series of openings arranged along the length of the inflow pipe so as to cause a cyclonic motion of the contaminated water out of the inflow pipe and into contact with the at least one cylindrical filter component, a first outflow pipe that delivers filtered water from the at least one cylindrical filter component, and a second outflow pipe that delivers contaminants from the at least one cylindrical filter component.
US09005433B2 Integrated process for in-situ organic peroxide production and oxidative heteroatom conversion
An oxidative treatment process, e.g., oxidative desulfurization or denitrification, is provided in which the oxidant is produced in-situ using an aromatic-rich portion of the original liquid hydrocarbon feedstock. The process reduces or replaces the need for the separate introduction of liquid oxidants such as hydrogen peroxide, organic peroxide and organic hydroperoxide in an oxidative treatment process.
US09005431B2 Process and apparatus for distributing hydrocarbon feed to a catalyst stream
A process and apparatus described is for distributing hydrocarbon feed to catalyst in a riser. Hydrocarbon feed is delivered to a plenum in the riser. Nozzles from the plenum inject feed into the riser to contact the catalyst. Streams of regenerated catalyst and carbonized catalyst may be passed to the riser and mixed around an insert in a lower section of a riser. The plenum may be located in the riser.
US09005423B2 Pipeline communications
Communications systems are provided for use with an impressed current cathodic protection (ICCP) system having single or multiple ICCP components. A pipeline may be provided by connecting multiple pipeline sections together as an integrated pipeline where each section has an associated ICCP system. A communications signal comprising an AC signal is impressed on the pipeline and received by receivers associated with power supplies associated with each ICCP system. Upon reception of the AC signal, a controllable switch is operated within the power supplies to synchronously disconnect them from their power source and thereby enable accurate testing of the ICCP system.
US09005421B2 Silicides for photoelectrochemical water splitting and/or the production of electricity
The invention relates to a method for the photoelectrochemical production of hydrogen and oxygen and for the simultaneously or separately conducted photoelectrical/photovoltaic production of electricity, characterized in that water is brought into contact with silicides, while applying light at the same time, or the contact with water can be foregone if electricity is produced exclusively. The invention enables the production of hydrogen and oxygen in a simple way directly from water, wherein the use of UV light and cost-intensive catalysts can be foregone.
US09005419B2 Composition and method for gel electrophoresis with in-situ calibration
The invention relates to, among other things, a method for performing electrophoresis with in-situ calibration. The method includes combining a volume of a test sample with a volume or quantity of a calibrating sample to form a final volume, where the volume of the calibrating sample includes a known concentration of a calibrator and the final volume includes a known ratio of test sample to calibrating sample. The method also includes depositing a loading fraction in a receiving well of an electrophoretic gel, in which the loading fraction is a fraction of the final volume, and separating the loading fraction along a common separation lane of the electrophoretic gel such that components of the test sample and the calibrator are separated from one another along the common separation lane. The method also includes detecting the calibrator and separated components of the test sample within the common separation lane and measuring the level of the calibrator and separated components of the test sample based on the detecting, thereby performing electrophoresis with in-situ calibration.
US09005417B1 Devices, systems, and methods for microscale isoelectric fractionation
Embodiments of the present invention provide devices, systems, and methods for microscale isoelectric fractionation. Analytes in a sample may be isolated according to their isoelectric point within a fractionation microchannel. A microfluidic device according to an embodiment of the invention includes a substrate at least partially defining a fractionation microchannel. The fractionation microchannel has at least one cross-sectional dimension equal to or less than 1 mm. A plurality of membranes of different pHs are disposed in the microchannel. Analytes having an isoelectric point between the pH of the membranes may be collected in a region of the fractionation channel between the first and second membranes through isoelectric fractionation.
US09005415B2 Electrode strip and sensor strip and manufacture method thereof and system thereof
The present disclosure relates to an electrode strip, a sensor strip, a system thereof and a manufacturing method thereof. The sensor strip includes a first reactive film, a second reactive film and a vent hole. The first reactive film includes a substrate, a first electrode layer and a first insulation layer. The first end of the first insulation layer is concaved to a first depth to form a first reactive area. The second reactive film includes a second electrode layer and a second insulation layer. The first end of the second insulation layer is concaved to a second depth to form a second reactive area. The vent hole penetrates the second insulation layer, the second electrode layer and the first insulation layer so as to connect the first reactive area and the second reactive area.
US09005413B2 Film formation apparatus
A film formation apparatus includes: a chamber having an inner space in which both a body to be processed and a target are disposed so that the body to be processed and the target are opposed to each other, a first magnetic field generation section generating a magnetic field in the inner space to which the target is exposed; a second magnetic field generation section generating a perpendicular magnetic field so as to allow perpendicular magnetic lines of force thereof to pass between the target the body to be processed; and a third magnetic field generation section disposed at upstream side of the target as seen from the second magnetic field generation section.
US09005412B2 Electrolyzer
An exemplary electrolyzer includes an electrode plate assembly including a plurality of perforated electrode plates and electrically conductive busbars. The plurality of electrode plates includes one or more positive electrode plates interleaved with one or more negative electrode plates. Each electrode plate has a first aperture and a second aperture, the second aperture being larger than the first aperture and lined with a non-conductive grommet. The plurality of electrically conductive busbars includes a first positive conductive busbar and a first negative conductive busbar. Respective conductive busbars extend through the first aperture of corresponding positive and negative electrodes and through the non-conductive grommet of the second aperture of each corresponding negative and positive electrode. The first positive conductive busbar is in electrical contact with each positive electrode and insulated from each negative electrode, and the first negative conductive busbar is in electrical contact with each negative electrode and insulated from each positive electrode.
US09005411B2 Electrochemical compression system
An electrochemical compressor includes one or more electrochemical cells through which a working fluid flows, and an external electrical energy source electrically connected to the electrochemical cell. Each electrochemical cell includes an anode connected to the electrical energy source; a cathode connected to the electrical energy source; an ion exchange membrane disposed between and in electrical contact with the cathode and the anode to pass an electrochemically motive material of the working fluid from the anode to the cathode, the ion exchange membrane comprising polar ionic groups attached to nonpolar chains; and a non-aqueous solvent comprising polar molecules, the polar molecules of the non-aqueous solvent being associated with and electrostatically attracted to the polar ionic groups of the ion exchange membrane.
US09005409B2 Electro chemical deposition and replenishment apparatus
An electrochemical deposition apparatus adapted to deposit metal onto a surface of a substrate, the apparatus has a frame configured for holding a process electrolyte. A substrate holder is removably coupled to the frame, the substrate holder supporting the substrate in the process electrolyte. An anode fluid compartment is removably coupled to the frame and containing an anolyte and having an anode facing the surface of the substrate, the anode fluid compartment further having a ion exchange membrane disposed between the anode and the surface of the substrate, the anode fluid compartment removable from the frame as a unit with the ion exchange membrane and the anode. The holder, the anode and the membrane are arranged in the frame so that ions from the anode pass through the ion exchange membrane into and primarily replenish ions in the process electrolyte depleted by ion deposition onto the surface of the substrate.
US09005408B2 Method and apparatus for extracting noble metals from inorganic granular waste catalysts
The leaching and precipitation of noble metals when circulating an electrolyte through a vertical cylindrical electrolytic cell comprising a fixed granular catalyst bed and a three-dimensional cathode filled with activated carbon granules are performed in the same step. Because the electrochemical leaching process and the electrochemical sorption process are performed simultaneously, the consumption of electric energy is reduced and the use of equipment becomes easy. An apparatus for extracting noble metals from inorganic granular waste catalysts comprises a vertical type electrolytic cell, conduit lines, an electrolyte circulating pump, a unit for automatically maintaining the required acidity of the electrolyte being circulated, a filter for filtering activated carbon particles from the electrolyte, control valves, and stop valves. The electrolytic cell comprises a heat exchanger for heating the electrolyte being circulated, an insoluble anode and a three-dimensional cathode filled with activated carbon granules.
US09005407B2 Method of fabricating composite field emission source
A method of fabricating a composite field emission source is provided. A first stage of film-forming process is performed by using RF magnetron sputtering, so as to form a nano structure film on a substrate, in which the nano structure film is a petal-shaped structure composed of a plurality of nano graphite walls. Afterward, a second stage of film-forming process is performed for increasing carbon accumulation amount on the nano structure film and thereby growing a plurality of nano coral-shaped structures on the petal-shaped structure. Therefore, the composite field emission source with high strength and nano coral-shaped structures can be obtained, whereby improving the effect and life of electric field emission.
US09005405B2 Extractive distillation process for benzene recovery
Recovering high purity benzene from hydrocarbon feedstock containing aromatics and non-aromatics is implemented by simple and low-cost modifications to conventional extractive distillation columns (EDCs). Methyl cyclohexane (MCH) that is generated through non-selective hydrogenation of toluene in hydrodesulfurization (HDS) units is a major contaminant in benzene production. To meet MCH specifications, often times the extractive distillation (ED) process for recovering purified benzene is operated with excessive benzene loss to the overhead raffinate stream, producing a lower quality non-aromatic product. Novel techniques (1) remove operational constrictions of the HDS unit on MCH production, thus lengthening the catalyst life and (2) allow the EDC to drive essentially any amount of MCH away from the bottom benzene product without concerns with benzene loss to the overhead raffinate stream and (3) recover benzene from the overhead raffinate stream to upgrade the quality of non-aromatic product and increase the benzene product recovery.
US09005403B2 Rotary evaporator
A rotary evaporator comprising a motor, a rotary joint movably inserted to a motor rotor of the motor by a sleeve in an axial direction, a collection flask attached to the rotary joint at one end of the joint, with a condenser attached to the other end of the joint. The condenser is adapted to receive a cooling coil from an immersion cooler. The cooling coil is attached to the base unit of the immersion cooler via an insulated hose. The rotary evaporator is adapted to provide various ways to remove heat from the flask in the water bath, whether by mechanically lowering the water bath, dropping fluid from the bath into an underlying reservoir, or raising and lowering the rotary evaporator out of the bath. Where the rotary evaporator is raised and lowered, the immersion cooler can remain in place if the hose connecting the base unit to the cooling coil is sufficiently long, or the condenser includes a flexible portion that accommodates the upward and downward movement.
US09005400B2 Device and method for controlling the conversion of biomass to biofuel
Embodiments presented herein describe an apparatus and method to control the conversion of carbonaceous materials, particularly biomass and those biomass resources, into a high performance solid fuel. This method, and the apparatus described as the means to accomplish this method, provides a process having a control system that enables the system to produce a fuel of uniform quality, even with a change in biomass supply.
US09005399B2 Pin seamed press felt with triple layer base fabric
A press felt includes: a base fabric comprising a plurality of repeat units, each of the repeat units comprising a plurality of exterior machine direction (MD) yarns, each of which includes an upper run and a lower run merging with seam loops at each end, a plurality of middle MD yarns positioned between the upper and lower runs of the exterior MD yarns, a plurality of cross machine direction (CMD) yarns interwoven with the exterior MD yarns and the middle MD yarns in a predetermined regular weave pattern, the seam loops defining the longitudinal ends of the press felt; and a batt layer overlying the base fabric.
US09005398B2 Composition and use of hydrogenated alkyl ketene dimers
Latent dispersants were made by the hydrogenation of an alkyl ketene dimer, alkenyl ketene dimer, or ketene multimer. Adding the latent dispersant to paper or paperboard increased its resistance to water and water vapor while maintaining recyclability and repulpability. Additionally, provided is a method for increasing the repulpability of a wax coated paper or paperboard. Dispersants made by the hydrolysis of the alkyl ketene dimer, alkenyl ketene dimer, and ketene multimer are also described.
US09005394B2 Anti-soiling agent composition
[Object] To provide an anti-soiling agent compound that can sufficiently prevents adhesion of pitch to a dry part region.[Solution] The present invention provides an anti-soiling agent composition for preventing pitch contamination in a dry part of a paper-making process, and the composition has a polysiloxane compound represented by the following formula (1), wherein the number of amino-modified groups per molecule of the polysiloxane compound is in a range from 0.5 to 5.[wherein, a substituent R1 represents a methyl group or an amino-modified group represented by the following formula (2), and the number n of repeating siloxane units represents an integer in a range from 50 to 1000, andwherein, each of a substituent R2 and a substituent R3 independently represents an alkylene group having carbon atoms of 1 to 6, and the number m of repeating amino-alkylene units represents an integer in a range from 0 to 2].
US09005393B2 Method and apparatus for phase change enhancement
A method of operating an evaporator is described. In evaporator feed water, a Taylor bubble is developed which has an outer surface including a thin film in contact with an inner surface of an outer wall of an evaporator tube. The Taylor bubble is heated as it rises within the evaporator tube so that liquid in the thin film transitions into vapor within the bubble.
US09005392B2 Apparatuses and methods for seaming substrates
A method of joining substrate portions includes positioning the substrate portions such that the substrate portions overlap at an overlap area. The substrate portions each have a melting temperature and an outer surface. A fluid is heated to a temperature sufficient to at least partially melt the substrate portions. A jet of the heated fluid is directed from a fluid orifice onto the substrate portions at the overlap area. The heated fluid penetrates at least one of the outer surfaces of the substrate portions. The substrate portions are at least partially melted using the heated fluid. The substrate portions are compressed using a pressure applying surface adjacent the fluid orifice to join the substrate portions together at the overlap area.
US09005391B2 Method and apparatus for transfer lamination
An embodiment of the inventive method of transfer lamination bonding a first metallized side of a film to a substrate. Then a breakaway coating is applied to a second, non-metallized side of the film after the first metallized side has been bonded to the substrate. The bonded film and substrate are then placed in an oven. The film is then stripped from the substrate leaving metal from the film deposited on the substrate. The application of the breakaway coating is performed as an inline part of the transfer lamination process thereby providing an ease of manufacture presently unknown.
US09005381B2 Method of moulding a wind turbine blade
A method of molding a wind turbine blade in a mold is provided. The method includes applying a film to an inside surface of a mold, assembling component layers for the wind turbine blade on the film, performing curing to harden the component layers, and subsequently removing the cured wind turbine blade from the mold. Also provided is a film suitable for use in a wind turbine blade molding process and a mold suitable for molding a wind turbine blade.
US09005380B2 High performance liquid rocket propellant
Disclosed is a high performance hydrocarbon fuel characterized by a hydrogen content greater than 14.3% by weight, a hydrogen to carbon atomic ratio greater than 2.0 and/or a heat of combustion greater than 18.7 KBtu/lb. The disclosed fuels generally have a paraffin content that is at least 90% by mass and a C12-C20 isoparaffin content of at least 40% by mass.
US09005379B2 Process for obtaining a pipe for supplying fuel to an internal combustion engine
The present invention relates to a process for producing a pipe, particularly for supplying fuel to an engine, comprising the steps of: prearranging a pipe made of stainless steel (1), executing a hot-pressing operation at at least one end (3) of the pipe (1); and subjecting the at least one end (3) of the pipe (1) to heat treatment, followed by cooling.
US09005377B2 Method of modifying a physical property of an endodontic instrument
Methods for modifying a physical characteristic of finished endodontic instruments made from one or more superelastic alloys is described which include heat treating one or more finished endodontic instruments in a salt bath for a specific time (e.g., from about four hours to about six hours), at a specified temperature (e.g., from about 475° C. to about 550° C.), and preferably at a specified pH range.
US09005374B2 Permanent magnet and manufacturing method thereof
There are provided a permanent magnet and a manufacturing method thereof capable of decreasing an activity level of a calcined body activated by a calcination process. To fine powder of milled neodymium magnet is added an organometallic compound solution containing an organometallic compound expressed with a structural formula of M-(OR)x (M represents V, Mo, Zr, Ta, Ti, W or Nb, R represents a substituent group consisting of a straight-chain or branched-chain hydrocarbon, x represents an arbitrary integer) so as to uniformly adhere the organometallic compound to particle surfaces of the neodymium magnet powder. Thereafter, desiccated magnet powder is held for several hours in hydrogen atmosphere at 200 through 900 degrees Celsius. Thereafter, the powdery calcined body calcined through the calcination process in hydrogen is held for several hours in vacuum atmosphere at 200 through 600 degrees Celsius for a dehydrogenation process.
US09005373B2 Treatment solution for producing chrome and cobalt-free black conversion coatings
The invention relates to chromium- and cobalt-free treatment solutions for producing black coatings which afford corrosion protection. The treatment solution of the invention contains oxo cations or complex halogen ions or mixtures of oxo cations and complex halogen ions, an oxidant and an organic sulphur compound.
US09005368B2 Method for operating a dishwasher
In a method for operating a dishwasher containing wash items, in particular a household dishwasher, at least at times a heated liquid to the wash items is applied during at least two of a plurality of program steps. A desorption process for desorption of a reversibly dehydratable drying material of a sorption drying system is effected at least at times. The desorption process is carried out at least partially before or during a first of the at least two program steps, with heated liquid being applied to the wash items during the at least two program steps.
US09005365B2 Method and apparatus for depositing LED organic film
In one embodiment the disclosure relates to an apparatus for depositing an organic material on a substrate, including a source heater for heating organic particles to form suspended organic particles; a transport stream for delivering the suspended organic particles to a discharge nozzle, the discharge nozzle having a plurality of micro-pores, the micro-pores providing a conduit for passage of the suspended organic particles; and a nozzle heater for pulsatingly heating the micro-pores nozzle to discharge the suspended organic particles from the discharge nozzle.
US09005364B2 Palette modular device for collection and recovery of metals in thin film deposition equipment
An electro-mechanical system for the collection and recovery of materials inside thin-film deposition facilities, comprising multiple elements able to intercept the wasted particles of material during a coating process. These elements are disposed in individual modules (1, 5), possibly combined in multiple configurations according to the shape of the deposition chamber; swivel, depending on the material to be recovered, thanks to a power unit (4), a transmission system (6, 10, 15a, 15b), an electronic interface (9) to automate the rotation of the elements. These elements can be palettes (3) placed vertically in each of the modules (1, 5), made of a composite material, characterized by a core of metallic material or alumina and by two surface polymeric layers with low adhesion to the selected core and therefore easily removable, but at the same time resistant to the temperature and pressure conditions inside the deposition chamber.
US09005362B2 Method for growing group III nitride crystal
The present invention is to provide a method for growing a group III nitride crystal that has a large size and has a small number of pits formed in the main surface of the crystal by using a plurality of tile substrates. A method for growing a group III nitride crystal includes a step of preparing a plurality of tile substrates 10 including main surfaces 10m having a shape of a triangle or a convex quadrangle that allows two-dimensional close packing of the plurality of tile substrates; a step of arranging the plurality of tile substrates 10 so as to be two-dimensionally closely packed such that, at any point across which vertexes of the plurality of tile substrates 10 oppose one another, 3 or less of the vertexes oppose one another; and a step of growing a group III nitride crystal 20 on the main surfaces 10m of the plurality of tile substrates arranged.
US09005361B2 Defoamer compositions for building-product mixtures
The present application relates to compositions comprising at least one siloxane and at least one superplasticizer based on polycarboxylate ethers or sulphonates of lignin, melamine or naphthalene or of resins thereof, and to the use of such compositions as or in building-product mixtures or building products, especially mortar mixtures or concrete mixtures. Preferably the siloxane is a branched siloxane containing at least one “T” unit and containing at least two different polyoxyalkylene moieties.
US09005357B2 Method of preparing molybdenum oxide films
Present invention relates to methods of preparing molybdenum oxide inks and molybdenum oxide films, and use of the molybdenum oxide films as hole-transporting layers in optoelectronic devices. The ink for forming a hybrid molybdenum (VI) oxide (MoO3) film on a substrate comprises an ammonium molybdate, at least one inorganic salt different from ammonium molybdate, and a solvent or a solvent mixture.
US09005352B2 Trap canister for adsorbing fuel vapor
Embodiments of the invention are directed towards a trap canister for adsorbing fuel vapor contained in breakthrough gas discharged from a main adsorbent canister. The main adsorbent canister is connected to a fuel tank has a case defining an adsorption chamber therein and an adsorbent filled in the adsorption chamber. The case has a first end open to the atmosphere and a second end for introducing breakthrough gas into the adsorption chamber. The adsorbent filled in the adsorption chamber adsorbs the fuel vapor contained in the breakthrough gas. The trap canister further has a bypass path for bypassing the adsorption chamber and a valve configured to block the bypass path and to allow for opening during refueling. This prevents the fuel vapor from flowing into the atmosphere during normal operation while also decreasing pressure loss during refueling.
US09005351B2 Desiccant tablet encapsulated in a special cloth
The invention relates to a system of encapsulating a hygroscopic salt tablet of the type used to absorb moisture in closed environments. Said encapsulation consists of seamless cloth, usually “non-woven”, arranged so that it includes folds that minimize the air chamber between the tablet and the covering thereof. Said arrangement allows the tablet to work more effectively than other similar ones by eliminating the resistance that the air causes to the absorption of moisture. Said tablet begins to work when the ambient moisture is greater than 55%-60% and is used inside a plastic device that has slots to absorb the moist air and has a bottom container for deposit of a brine resulting from the process of absorbing moisture.
US09005350B2 Trap canisters
A trap canister for adsorbing fuel vapor contained in break-through gas discharged from a main canister. The trap canister may include a trap case having an adsorption chamber defined therein and containing an adsorption material, so that the break-through gas flows through the adsorption material in a gas flow direction. The adsorption chamber may include a gas introduction side and a gas outlet side located on a downstream side of the gas introduction side along the gas flow direction. The adsorption chamber may have a passage with a cross-sectional area gradually decreasing from the gas introduction side toward the gas outlet side. The trap canister may further include a temperature control device configured to control the temperature of the adsorption material.
US09005343B2 Integrated leukocyte, oxygen and/or CO2 depletion, and plasma separation filter device
A blood filter device comprising: a housing comprising an outer wall and a first inlet, a first outlet and a second outlet; a membrane which is capable of separating plasma from the blood, wherein the membrane forms an inner chamber; a leukocyte and oxygen and/or carbon dioxide depletion media disposed wherein the inner chamber, the leukocyte and oxygen and/or carbon dioxide depletion media is capable of depleting leukocytes and oxygen and/or carbon dioxide from the blood; an outer chamber disposed between the outer wall and the membrane, wherein the plasma which permeates through the membrane enters the outer chamber and exits the filter device via the first outlet; whereby the blood which has been depleted of oxygen and/or carbon dioxide, leukocytes and plasma exists and filter device via the second outlet.
US09005341B2 Sealing device and method
The present disclosure relates to a sealing device 20 for a control rod 17, passing through an aperture 15c in a wall 15, wherein the control rod 17 is connected between an actuator 13, placed on one side of the wall, and a controlled entity 9a, placed on the other side of the wall, such that the actuator can control the controlled entity with motion of the control rod. The sealing device 20 includes a packing box 37 through which the control rod 17 passes and a seal 41 which provides a sealing function between the control rod 17 and the packing box 37. The packing box 37 is moveable with the control rod 17 in relation to the wall 15. Wall aperture 15c is sized to allow movement of the control rod 17 within aperture 15c. A flexible member 39 surrounds a portion of control rod 17 and extends between the packing box 37 and the wall 15, in a gastight communication with each. As such, the subject sealing device allows movement of the control rod without compromising the sealing function efficiency thereof.
US09005336B2 Monoterpene component-rich essential oil, method for producing same and method for remediating environmental pollutants using the essential oil
To develop a means for effectively utilize terpene compounds contained in tree leaves, whereby branches and leaves cut in tree thinning and pruning can be effectively utilized as a resource. For this purpose, provided are a monoterpene component-rich essential oil containing 90% or more of monoterpene components; a method for producing the monoterpene component-rich essential oil which includes subjecting coniferous leaves to microwave steam distillation and collecting a distillate thus obtained; and a method for removing environmental pollutants which includes bringing the monoterpene component-rich essential oil into contact with atmosphere containing the environmental pollutants.
US09005334B2 Water-proof air-permeable filter and use of the same
A water-proof air-permeable filter (1) includes: a resin film (2) having formed therein a plurality of through pores (21); and a treated layer (3) having hydrophobicity and oil repellency, and formed on at least one of both surfaces in the thickness direction of the resin film (2) such that the treated layer (3) has openings (31) at positions corresponding to the through pores (21). The through pores (21) each have a predetermined size larger than or equal to 0.01 μm and smaller than or equal to 10 μm, and are uniformly distributed such that a density of the through pores falls within specific limits included in a range from 10 to 1×108 pores/mm2.
US09005333B1 Systems and methods for reducing ammonia emissions from and for recovering the ammonia liquid effluents
A system and method for passive capture of ammonia in an ammonia-containing liquid effluent. The invention allows for the passage of ammonia through microporous hydrophobic gas-permeable membranes and its capture in a circulated stripping solution with concomitant production of a concentrated non-volatile ammonium salt.
US09005331B2 Platinum-coated non-noble metal-noble metal core-shell electrocatalysts
Core-shell particles encapsulated by a thin film of a catalytically active metal are described. The particles are preferably nanoparticles comprising a non-noble core with a noble metal shell which preferably do not include Pt. The non-noble metal-noble metal core-shell nanoparticles are encapsulated by a catalytically active metal which is preferably Pt. The core-shell nanoparticles are preferably formed by prolonged elevated-temperature annealing of nanoparticle alloys in an inert environment. This causes the noble metal component to surface segregate and form an atomically thin shell. The Pt overlayer is formed by a process involving the underpotential deposition of a monolayer of a non-noble metal followed by immersion in a solution comprising a Pt salt. A thin Pt layer forms via the galvanic displacement of non-noble surface atoms by more noble Pt atoms in the salt. The overall process is a robust and cost-efficient method for forming Pt-coated non-noble metal-noble metal core-shell nanoparticles.
US09005329B2 Fine grained cemented carbide with refined structure
The present invention relates to a fine grained WC-Co cemented carbide. By adding an extremely small amount of Ti, V, Zr, Ta or Nb alone or in combinations, a grain refined cemented carbide structure with less abnormal WC-grains has been obtained.
US09005327B2 Apparatus, method and system for receiving and/or discharging medium for disposal
A device for receiving and/or discharging a disposal medium from cleaning and/or rinsing processes of an application apparatus can comprise a separation equipment which is provided to receive the disposal medium discharged by the application device and to subject the disposal medium to a separation. The device can also comprise a receiving equipment which is provided to receive a disposal medium and a suction device which is provided to suction and/or suction off at least a part of the disposal medium led to or into the receiving equipment.
US09005326B2 Cyclone separator
A cyclone separator has individual cyclones each provided with a cell tube with a guide device that causes a gas stream passing through the cell tube to rotate. A particle discharge is positioned perpendicularly to a longitudinal axis of the cyclone separator and discharges particles separated from the gas stream. The discharge direction of the separated particle is perpendicular to the longitudinal axis of the cyclone separator and is oriented toward the particle discharge. The individual cyclones include at least four individual cyclones that are arranged such that a connecting line, connecting of these four individual cyclones those individual cyclones that are neighboring each other at a minimal spacing, respectively, forms a diamond, wherein the sides of the diamond are positioned at an angle of 30 to 60 degrees relative to discharge direction.
US09005325B2 Cyclonic separation apparatus
A cyclonic separation apparatus for a vacuum cleaner, the cyclonic separation apparatus comprising: a first cyclonic separating unit comprising a hollow cylindrical dirt container with a central axis and an air inlet port arranged tangentially through a side of the dirt container; a second cyclonic separating unit comprising at least one cyclone with an axial inlet port, an axial outlet port and a discharge nozzle and a substantially cylindrical intermediate wall surrounding the inlet port of the at least one cyclone, wherein the cyclonic separation apparatus comprises at least one protruding lip arranged to impede return of separated material from said longitudinal end of the dirt container and wherein the at least one lip protrudes radially inwardly from an inner surface of the dirt container or protrudes radially outwardly from the intermediate wall.
US09005320B2 Enhanced plasma gasifiers for producing syngas
A plasma gasification reactor, and process for its operation, with one or both of, first, a quench zone within an upper part of a top section of the reactor and, second, feed ports through a lateral wall of a middle section of the reactor for supplying feed material to a feed bed within the middle section and the feed ports located proximate the feed bed. The quench zone is provided with nozzles for introducing a fluid to reduce the temperature of molten solid bits sufficiently to minimize their sticking within external ductwork. The middle section feed port arrangement assists in more thorough reaction of light particles in the feed material that may otherwise exit with gaseous products.
US09005319B2 Tar removal for biomass gasification systems
The disclosed embodiments provide systems for the removal and use of tar from a biomass gasification system. For example, in one embodiment, a biomass gasification system includes a reactor configured to gasify a biomass fuel in the presence of air to generate a producer gas. The system also includes an absorber configured to receive a mixture of the producer gas and tar and to absorb the tar into an organic solvent to produce treated producer gas and a rich solvent mixture containing at least a portion of the tar. The system further includes a recycle line configured to direct the rich solvent mixture to a biomass gasifier.
US09005318B2 Process for upgrading low rank carbonaceous material
A process for upgrading brown coal having a first water content including subjecting the brown coal to a conditioning step which includes heating the brown coal to a first temperature to produce a conditioned brown coal having a second water content which is lower than the first water content; attritioning the conditioned brown coal to enable water to be released from the microstructure of the brown coal and thereby producing an admixture of the brown coal and released water; forming aggregates of the admixture; drying the aggregates to produce upgraded brown coal having a third water content which is lower than the second water content.
US09005317B2 Method for producing solid fuel and solid fuel produced by the method
Modified solid fuel manufacturing method and modified solid fuels manufactured using the manufacturing method. When solid fuels are manufactured by crushing low grade coal, mixing the crushed low grade coal with solvent oil to prepare a slurry, heating the slurry to at least the boiling point of water to evaporate moisture included in the slurry, separating the solvent oil from the slurry to produce charcoal dust and compression compacting said charcoal dust, by heating the slurry to at least the boiling point of water, the non-volatile components included in the low grade coal are extracted with the solvent oil, the outer surface of the low grade coal and the internal surfaces of the pores are coated with the extracted non-volatile components, and the content of heavy oil added from the outside will be less than 0.5 mass % relative to the solid fuel after drying.
US09005315B2 Bisphenol A compounds as markers for liquid hydrocarbons and other fuels and oils
A method for marking a petroleum hydrocarbon or a liquid biologically derived fuel by adding at least one compound having formula (I), wherein R1 and R2 independently represent hydrogen or C1-C4 alkyl groups, and G represents hydrogen or at least one substituent selected from the group consisting of C1-C18 alkyl and C1-C18 alkoxy.