Document Document Title
US08907382B2 Semiconductor device and fabrication method thereof
A semiconductor device is provided. An insulating buried layer is formed in a substrate. Deep trench insulating structures are formed on the insulating buried layer. A deep trench contact structure is formed between the deep trench insulating structures. The deep trench contact structure is electrically connected with the substrate under the insulating buried layer.
US08907381B2 Reduced short channel effect of III-V field effect transistor via oxidizing aluminum-rich underlayer
In one embodiment, a method of forming a semiconductor device is provided that may include forming a semiconductor device including a gate structure on a channel portion of III-V semiconductor substrate. The III-V semiconductor substrate including a III-V base substrate layer, an aluminum containing III-V semiconductor layer that is present on the III-V base substrate layer, and a III-V channel layer. Oxidizing a portion of the aluminum containing III-V semiconductor layer on opposing sides of the gate structure. Forming a raised source region and a raised drain region over the portion of the aluminum containing III-V semiconductor layer that has been oxidized. Forming interconnects to the raised source region and the raised drain region.
US08907374B2 Insulated gate bipolar transistor
Embodiments of the present invention provide an IGBT, which relates to the field of integrated circuit manufacturing, and may improve a problem of tail current when the IGBT is turned off. The IGBT includes a cell region on a front surface, a terminal region surrounding the cell region, an IGBT drift region of a first conductivity type, and an IGBT collector region on a back surface. The IGBT collector region is connected to the IGBT drift region and under the IGBT drift region. The IGBT drift region includes a first drift region under the cell region and a second drift region under the terminal region. The IGBT collector region includes a cell collector region of a heavily doped second conductivity type under the first drift region and a non-conductive isolation region adjacent to the cell collector region.
US08907371B2 Light emitting diode package and light emitting device having the same
An LED package includes a light transmissive encapsulation, an LED die embedded in the encapsulation from a bottom surface of the encapsulation, a positive electrode electrically connected to an anode of the LED die, and a negative electrode electrically connected to a cathode of the LED die. The encapsulation includes a light emitting surface opposite to the bottom surface thereof. The LED die includes a front surface for outputting light outward, and a back surface opposite to the front surface. The front surface is covered by the encapsulation and faces the light emitting surface of the encapsulation. The back surface is exposed outside. A light emitting device is provided by mounting the LED package to a circuit board. The circuit board has a heat conductor connecting with the LED die.
US08907370B2 Electronic devices with yielding substrates
In accordance with certain embodiments, a semiconductor die is adhered directly to a yielding substrate with a pressure-activated adhesive notwithstanding any nonplanarity of the surface of the semiconductor die or non-coplanarity of the semiconductor die contacts.
US08907368B2 Double collimator LED color mixing system
The present invention is directed to a lighting apparatus. In one embodiment the lighting apparatus includes a plurality of light emitting diode (LED) chips. A first optic is coupled to the plurality of LED chips. A diffuser is coupled to the first optic. In addition, a second optic is coupled to the diffuser.
US08907365B2 OLEDs comprising light extraction substructures and display devices incorporating the same
An organic light emitting diode comprising a light extraction substructure and a diode superstructure is provided. The light extraction substructure comprises a light expulsion matrix distributed over discrete light extraction waveguide elements and a waveguide surface of the glass substrate. The light expulsion matrix is distributed at varying thicknesses to enhance the planarity of a diode superstructure-engaging side of the light extraction substructure and to provide light expulsion sites at the waveguide element termination points of the discrete light extraction waveguide elements. In operation, light originating in the organic light emitting semiconductor material of the diode superstructure is coupled to the discrete waveguide elements of the light extraction substructure as respective coupled modes characterized by an approximate coupling length defined as the propagation distance required for an optical mode to be coupled from the superstructure waveguide to one of the discrete waveguide elements of the light extraction substructure.
US08907364B2 LED package comprising encapsulation
Light emitting elements (110) are situated on a film (210), then surrounded by a reflective structure (250) that is placed or formed on the film (210). Thereafter, the reflective structure (250) is filled with an encapsulant (270), affixing the light emitting element (110) within the reflective structure (250). The film (210) may then be removed, exposing the contacts (230) for coupling the light emitting element (110) to an external power source. The encapsulated light emitting elements (110) within the reflective structure (250) are diced/singulated to provide the individual light emitting devices. The encapsulant (270) may be molded or otherwise shaped to provide a desired optical function.
US08907363B2 Light emitting device, light emitting device package and lighting system including the same
A light emitting device is described, including a second conductive type semiconductor layer; an active layer over the second conductive type semiconductor layer; a first conductive type semiconductor layer over the active layer; a second electrode in a first region under the second conductive type semiconductor layer; a current blocking layer including a metal; and a first electrode over the first conductive type semiconductor layer. Further, the first electrode has at least one portion that vertically overlaps the current blocking layer.
US08907356B2 LED package structure
An LED package structure comprises a 3D substrate, LED chips, wires, and resin encapsulants. The 3D substrate has a stepped contour and includes a first chip accommodation region and at least one second chip accommodation region surrounding the first chip accommodation region. A first electric contact and a second electric contact are arranged in the first chip accommodation region. The LED chips are arranged in the border of the 3D substrate. The wires are used to connect the LED chips in series or in series firstly and in parallel next. One of the wires connects the first electric contact and one of the LED chips. Another one of the wires connects the second electric contact and another one of the LED chips. The resin encapsulants respectively encapsulate the LED chips. The LED package structure is characterized in using a 3D substrate to facilitate wiring and increase the beam angle.
US08907347B2 Thin film transistor array panel and method for manufacturing the same, and liquid crystal display
A thin film transistor array panel includes a substrate, a first thin film transistor formed on the substrate, a color filter formed on the first thin film transistor and having a through hole, a capping layer formed on the color filter and having an opening, and a pixel electrode formed on the capping layer and connected to the first thin film transistor through the through hole. The opening exposes the color filter outside the through hole.
US08907346B2 Imprint apparatus, imprint method, and manufacturing method of semiconductor device
An imprint apparatus according to embodiments includes a stage, a dropping unit that drops resist, an imprinting unit that presses a circuit pattern of a template against the resist on a transfer target substrate, an underlying position detecting unit, a correcting unit, and a dropping position control unit. The underlying position detecting unit detects a position of an underlying pattern on the transfer target substrate. The correcting unit corrects a dropping position of the resist on a basis of a position of the underlying pattern. The dropping position control unit causes the resist to be dropped onto a dropping position after correction on the transfer target substrate on the basis of corrected dropping position.
US08907342B2 Thin film transistor array substrate, color filter substrate and display device
Embodiments of the disclosed technology provide to a thin film transistor array substrate comprising a first base substrate; a gate line formed on the first base substrate; and two data lines separately formed on the first base substrate; wherein the two data lines are located on both sides of the gate line respectively in the direction of data signal transmission but do not overlap with the gate line. The two data lines can be electrically connected through conductive elements for transmitting data signals.
US08907341B2 Thin-film semiconductor device and method for fabricating thin-film semiconductor device
A thin-film semiconductor device includes a semiconductor device part and a capacitor part. The semiconductor device part includes: a light-transmitting first gate electrode; a light-shielding second gate electrode; a first insulating layer; a semiconductor layer; a second insulating layer; and a source electrode and a drain electrode. The capacitor part includes: a first capacitor electrode made of a light-transmitting conductive material; a dielectric layer; and a second capacitor electrode. The second gate electrode, the semiconductor layer, and the second insulating layer have outlines that are coincident with one another in a top view.
US08907339B2 X-ray detector
An X-ray detector including a thin film transistor (TFT) substrate and a photo-diode array layer is disclosed. Each thin film transistor in the TFT substrate includes: a substrate; a gate-electrode on the substrate; a gate insulating layer on the gate-electrode; a semiconductor layer on the gate insulating layer, wherein a portion of the semiconductor layer covers the gate-electrode; an etching stop layer covering the semiconductor layer; a source-electrode and a drain-electrode respectively disposed on the etching stop layer, wherein the source-electrode and the drain-electrode are respectively electrically connected to the semiconductor layer through conductive via-holes each having a base portion at the semiconductor layer, and at least one of the projection areas of the base portions vertically projected on the substrate has a non-overlapping region beyond the projection area of the gate-electrode vertically projected on the substrate; and a passivation layer covering the source-electrode and the drain-electrode.
US08907336B2 Stable amorphous metal oxide semiconductor
A thin film semiconductor device has a semiconductor layer including a mixture of an amorphous semiconductor ionic metal oxide and an amorphous insulating covalent metal oxide. A pair of terminals is positioned in communication with the semiconductor layer and define a conductive channel, and a gate terminal is positioned in communication with the conductive channel and further positioned to control conduction of the channel. The invention further includes a method of depositing the mixture including using nitrogen during the deposition process to control the carrier concentration in the resulting semiconductor layer.
US08907335B2 Display device and method for manufacturing the same
With an increase in the definition of a display device, the number of pixels is increased, and thus the numbers of gate lines and signal lines are increased. The increase in the numbers of gate lines and signal lines makes it difficult to mount an IC chip having a driver circuit for driving the gate line and the signal line by bonding or the like, which causes an increase in manufacturing costs. A pixel portion and a driver circuit driving the pixel portion are provided over the same substrate. The pixel portion and at least a part of the driver circuit are formed using thin film transistors in each of which an oxide semiconductor is used. Both the pixel portion and the driver circuit are provided over the same substrate, whereby manufacturing costs are reduced.
US08907334B2 Oxide for semiconductor layer of thin-film transistor, sputtering target, and thin-film transistor
Disclosed is an oxide for a semiconductor layer of a thin-film transistor, said oxide being excellent in the switching characteristics of a thin-film transistor, specifically enabling favorable characteristics to be stably obtained even in a region of which the ZnO concentration is high and even after forming a passivation layer and after applying stress. The oxide is used in a semiconductor layer of a thin-film transistor, and the aforementioned oxide contains Zn and Sn, and further contains at least one element selected from group X consisting of Al, Hf, Ta, Ti, Nb, Mg, Ga, and the rare-earth elements.
US08907331B2 Display unit and electronic apparatus
A display unit comprising an organic layer between a light-emitting section portion of a first electrode layer and a light-emitting section portion of a second electrode layer. Light is emissible from within the organic layer. An aperture-defining insulating film is between a contact section of the first electrode layer and a gap section portion of the second electrode layer. The thickness of the gap section portion of the second electrode layer is greater than the thickness of the light-emitting section portion of the second electrode layer.
US08907330B2 Organic light emitting diode display and manufacturing method thereof
An organic light emitting diode display including a substrate, a first electrode on the substrate, a light-emitting layer on the first electrode, a second electrode on the light-emitting layer, and a p-doping layer between the first electrode and the light-emitting layer.
US08907313B2 Controlling ReRam forming voltage with doping
An internal electrical field in a resistive memory element can be formed to reduce the forming voltage. The internal electric field can be formed by incorporating one or more charged layers within the switching dielectric layer of the resistive memory element. The charged layers can include adjacent charge layers to form dipole layers. The charged layers can be formed at or near the interface of the switching dielectric layer with an electrode layer. Further, the charged layer can be oriented with lower valence substitution side towards lower work function electrode, and higher valence substitution side towards higher work function electrode.
US08907312B2 Cytometry system with solid numerical-aperture-increasing lens
A flow cytometry system includes a flow element through which a cell is transported in a flowing fluid. The flow element includes a bore bounded by a wall. A light source is configured to illuminate the cell. An optical system receives light emanating from the cell and directs at least some of the received light to a light sensor. The optical system includes a numerical-aperture-increasing lens at a wall of the flow element. At least some of the received light passes through the numerical-aperture-increasing lens. The flow cytometry system may also include a beam splitter that directs two wavelength bands of the emanating light such that light in two wavelength band preferentially reach different sensing locations via different paths. The system may also include an optical element placed in one of the paths, shifting a focal location of the affected path to compensate for chromatic aberration of the numerical-aperture-increasing lens.
US08907310B2 EUV optics
In a first aspect, a method of fabricating an EUV light source mirror is disclosed which may comprise the acts/steps of providing a plurality of discrete substrates; coating each substrate with a respective multilayer coating; securing the coated substrates in an arrangement wherein each coated substrate is oriented to a common focal point; and thereafter polishing at least one of the multilayer coatings. In another aspect, an optic for use with EUV light is disclosed which may comprise a substrate; a smoothing layer selected from the group of materials consisting of Si, C, Si3N4, B4C, SiC and Cr, the smoothing layer material being deposited using highly energetic deposition conditions and a multilayer dielectric coating. In another aspect, a corrosion resistant, multilayer coating for an EUV mirror may comprise alternating layers of Si and a compound material having nitrogen and a 5th period transition metal.
US08907309B2 Treatment delivery control system and method of operation thereof
The invention relates to a method and apparatus for control of a charged particle cancer therapy system. A treatment delivery control system is used to directly control multiple subsystems of the cancer therapy system without direct communication between selected subsystems, which enhances safety, simplifies quality assurance and quality control, and facilitates programming. For example, the treatment delivery control system directly controls one or more of: an imaging system, a positioning system, an injection system, a radio-frequency quadrupole system, a ring accelerator or synchrotron, an extraction system, a beam line, an irradiation nozzle, a gantry, a display system, a targeting system, and a verification system. Generally, the control system integrates subsystems and/or integrates output of one or more of the above described cancer therapy system elements with inputs of one or more of the above described cancer therapy system elements.
US08907305B2 Charged particle detector
A charged particle beam system for imaging and processing targets is disclosed, comprising a charged particle column, a secondary particle detector, and a secondary particle detection grid assembly between the target and detector. In one embodiment, the grid assembly comprises a multiplicity of grids, each with a separate bias voltage, wherein the electric field between the target and the grids may be adjusted using the grid voltages to optimize the spatial distribution of secondary particles reaching the detector. Since detector lifetime is determined by the total dose accumulated at the area on the detector receiving the largest dose, detector lifetime can be increased by making the dose into the detector more spatially uniform. A single resistive grid assembly with a radial voltage gradient may replace the separate grids. A multiplicity of deflector electrodes may be located between the target and grid to enhance shaping of the electric field.
US08907302B2 Flow rectifier for closed pipelines
A channel for a UV irradiation device, in which the UV irradiation device is disposed in a closed channel and an inlet cone is provided in the direction of flow upstream of a UV reactor, which, as part of the wall of the channel, increases the cross section of the channel from an incoming pipeline cross section to a cross section of the reactor, in which a flow rectifier with at least one inner first guide element and at least one outer second guide element is disposed in the inlet cone, wherein the inner guide element is a substantially circular, cylindrical pipe and the outer guide element runs substantially parallel to the outer wall and is disposed at a distance from the outer wall.
US08907298B1 Method for axial alignment of charged particle beam and charged particle beam system
A method for axial alignment of a charged particle beam relative to at least three stages of multipole elements and a charged particle beam system capable of making the axial alignment. Some parts of the orbit of the beam or the distributions of three astigmatic fields, or both, are simultaneously translated in a direction perpendicular to the optical axis such that astigmatisms of the same order and same type due to axial deviations between successive ones of the astigmatic fields cancel.
US08907297B2 Multi-dimensional photocathode system
A photocathode system includes a plurality of photocathodes, and at least one combining device. The photocathodes have individually adjustable voltages, and each photocathode generates an individual electron bunch at an emission period. The combining device combines the individual electron bunches, generated at each emission period, into a combined bunch along a combined axis. The timing of the individual electron bunches is independently adjustable, so that an electron bunch with a lower energy arrives at the combined axis earlier in time compared to another electron bunch with a higher energy, thereby allowing the combined beam of electron bunches to be longitudinally compressed. The photocathodes may be distributed along a 1D column, or a 2D array, or a 3D array, or any arbitrary configuration. A linac is located near a longitudinal focusing point to boost beam energy and therefore freeze bunch length and emittance.
US08907296B2 Charged particle beam system aperture
An improved beam-defining aperture structure and method for fabrication is realized. An aperture opening is made in a thin conductive film positioned over a cavity in a support substrate, where the aperture size and shape is determined by the opening in the conductive film and not determined by the substrate.
US08907294B2 Image pickup apparatus, image pickup system, method for controlling image pickup apparatus, method for controlling image pickup system, and programs
An image pickup apparatus includes a detector having pixels divided into first and second pixel groups, a signal processor including a reading circuit unit including first and second reading circuits, an A/D conversion unit including first and second A/D converters, a digital data processing circuit, and a controller. The controller instructs the signal processor to perform a signal processing operation several times of adding direct current potentials to analog electric signals of pixels from the reading circuit unit, supplying the signals to the A/D conversion unit, and outputting digital data to the digital data processing circuit while the direct current potentials are changed, and an average processing operation of averaging the digital data for the pixels using the digital data processing circuit.
US08907293B2 Boron coated straw neutron detectors distributed in a moderator material
The present invention includes an apparatus and method for neutron radiation detection. The apparatus comprises combining thin walled, boron-coated straw tubes with a plastic moderator material interspersed around the tubes. The method involves using such an apparatus through application of voltage to a central wire running inside the tubes and collecting electrical pulses generated thereby.
US08907292B2 Tungstate-based scintillating materials for detecting radiation
A tungstate-based scintillating material and a method for using a tungstate-based scintillating material is provided. In addition, a radiation detector and an imaging device incorporating a tungstate-based scintillating material are provided.
US08907289B2 Subatomic particle detector capable of ignoring shock induced counts
A subatomic particle detection apparatus includes a scintillator to scintillate if struck by subatomic particles, and to scintillate if subjected to mechanical stresses, the scintillator to emit an electrical discharge if scintillating due to the mechanical stresses. A detector is optically coupled to the scintillator to detect scintillations by the scintillator. Furthermore, an antenna is associated with the scintillator and/or the detector to detect the electrical discharge. In addition, circuitry is coupled to the detector and the antenna to determine whether the scintillator scintillated due to the mechanical stresses, based upon the antenna detecting the electrical discharge.
US08907286B2 Gas phase cooling and mixture analysis
A system includes a cold cell tube configured to receive a mixture of a target gas and a buffer gas to cool the target gas to a temperature at which a partial pressure of the target gas is greater than the saturated vapor pressure of the target gas while maintaining at least a portion of the target gas in the gas phase. The system also includes a spectroscopic module configured to detect the cooled target gas in the cold cell tube; and an analysis module configured to determine a characteristic of the target gas based on the results of the detecting.
US08907285B2 Pyroelectric detector and method for manufacturing same, pyroelectric detection device, and electronic instrument
A pyroelectric detector includes a pyroelectric detection element, a support member, a fixing part and a first reducing gas barrier layer. A first side of the support member faces a cavity and the pyroelectric detection element is mounted and supported on a second side opposite from the first side. An opening part communicated with the cavity is formed on a periphery of the support member in plan view from the second side of the support member. The fixing part supports the support member. The first reducing gas barrier layer covers a first surface of the support member on the first side, a side surface of the support member facing the opening part, and a part of a second surface of the support member on the second side and the pyroelectric detection element exposed as viewed from the second side of the support member.
US08907283B2 Battery-operated object detecting device
A battery-operated object detecting device (D) includes a detecting unit (U) adapted to be driven by an electric cell (12) mounted thereon, and a transmitting device (20) driven by the electric cell (12) in the detecting unit (U) for wireless transmitting at least a low battery signal being indicative of a reduction in voltage of the electric cell (12). An electric power sharing unit (30) for outputting a supply voltage to the transmitting device (20) includes a voltage changing circuit (32) for changing, based on a low battery detection result from a low battery detecting circuit (13), to a voltage necessary for causing a low battery determining circuit (21) of the transmitting device (20) to change the supply voltage from the electric cell (12) to a voltage for determining a low battery state.
US08907275B1 Method and apparatus to improve the separation capacity in a sequence of ion filters incorporating at least two ion mobility analyzers
A method and an apparatus are described to improve the separation capacity of an ion analyzer incorporating at least two stages of ion mobility analysis. The new invention utilizes possible use of different mixtures of gases and dopants in each stage, control over different concentrations of gases and dopants in each stage, and allowance of passage of the selected ions from one stage to the next while avoiding the mixing of the gases and dopants among stages. The new invention also includes a method to reduce the time required to identify the physical properties in a set of ion filters where at least one of the filters is a scannable ion mobility analyzer. The present invention also includes how to provide a set of scannable ion mobility analyzers operating in series, wherein each stage can be operated as a filter, or allowing for the passage of all ions.
US08907273B1 Vacuum chamber for ion manipulation device
An ion manipulation method and device is disclosed. The device includes a pair of substantially parallel surfaces. An array of inner electrodes is contained within, and extends substantially along the length of, each parallel surface. The device includes a first outer array of electrodes and a second outer array of electrodes. Each outer array of electrodes is positioned on either side of the inner electrodes, and is contained within and extends substantially along the length of each parallel surface. A DC voltage is applied to the first and second outer array of electrodes. A RF voltage, with a superimposed electric field, is applied to the inner electrodes by applying the DC voltages to each electrode. Ions either move between the parallel surfaces within an ion confinement area or along paths in the direction of the electric field, or can be trapped in the ion confinement area. A predetermined number of pairs of surfaces are disposed in one or more chambers, forming a multiple-layer ion mobility cyclotron device.
US08907272B1 Radio frequency device to separate ions from gas stream and method thereof
A method for transporting ions within a mass spectrometer comprises: inputting the ions and neutral molecules to a first end of an ion transport apparatus comprising a plurality of non co-planar ring-shaped electrode portions having respective central apertures having centers that lie along a common axis and that define an ion channel, the radii of the central apertures decreasing in a direction from the first end to a second end of the ion transport apparatus; applying a set of Radio Frequency voltages to the plurality of electrode portions such that the ions remain substantially confined to the ion channel while passing from the first to the second end; and exhausting the neutral molecules from the ion transport apparatus though a plurality of channels or apertures other than the apertures that define the ion channel, the exhausting performed in one or more directions that are non-perpendicular to the axis.
US08907271B2 Introduction of ions into electrostatic ion traps
Ions are introduced into a Kingdon ion trap in which the ions can oscillate harmonically in a potential well in the longitudinal direction, essentially decoupled from their transverse motion by a Kingdon ion guide, which can consist of a drill-hole through the wall of the ion trap housing electrodes and a central wire. An injection potential is first applied to the wire, but once the heaviest ions of interest have been injected into the trap, the potential of the wire is switched to the potential of the housing electrodes, to trap the ions in the trap. The ions introduced into the Kingdon ion trap may come from a small ion cloud, located in a Paul trap.
US08907266B2 Light-receiving device array, optical receiver module, and optical transceiver
A light-receiving device array includes a photodiode array that is provided with plural light-receiving sections each of which includes a first conductivity type electrode and a second conductivity type electrode, and a carrier, wherein the carrier includes plural pair of electric lines each of which is formed from a first electric line connected to the first conductivity type electrode of each light-receiving section, and a second electric line connected to the second conductivity type electrode of the light-receiving section, a first ground electrode that extends between one pair of electric lines of the plural pair of electric lines and a pair of electric lines adjacent to the one pair of electric lines, and a second ground electrode that is formed on a part of the rear surface and is electrically connected to the first ground electrode.
US08907261B1 Electromagnetic wave detection
Embodiments of the invention are directed toward systems and methods for detecting a laser beam incident at a sensor. Embodiments of the invention may also determine the incident angle, the wavelength of the light, the power, and/or the pulse rate of the incident laser beam. This information can be used to conduct real time countermeasures and/or may be communicated to a control station. Some embodiments may also include a device that includes a photo detector and a m mask ask. The mask may include a plurality of line and/or circular apertures. Some of the apertures may be located on the mask to activate pixels in the top and/or bottom of the photo detector when illuminated from a zero angle (zenith). Embodiments of the invention also include methods that perform a number of related functions.
US08907256B2 Heater
There is disclosed a heater which does not excessively heat a lubricating fluid but can rapidly raise a temperature of the lubricating fluid, even when a size thereof is small. A heater includes a honeycomb structure section including partition walls which contain a ceramic as a main component and generate heat by electrical conduction, and a plurality of cells which are partitioned and formed by the partition walls and extend through the honeycomb structure section from one end to another end to become through channels of a lubricating fluid; and a pair of electrodes which become an anode and a cathode to come in contact with the honeycomb structure section, thereby conducting the electricity through the partition walls of the honeycomb structure section.
US08907252B2 Electric oven and procedure for cooking a food product in a very low level of fat substance
An electric oven for cooking a food product in a fat substance comprises a cooking chamber, at least one electrical heating resistance housed in the cooking chamber, a vessel mountable inside the cooking chamber and housing, at least one rotatable stirring blade that is able to rotate the food product to cover the food product with a film of fat substance, and a drive pin to drive said stirring blade in rotation. The stirring blade is configured so as to displace the food product such that at last a portion of the food product comes into contact with the fat substance for combined cooking by action of air on the portion of the food product located above the fat substance and by action of fat substance immersion at least on a portion of the food product immersed in said fat substance.
US08907244B2 Work measuring method, electric discharge machining method, and electric discharge machining apparatus
The present invention includes steps of, determining a search starting position; setting a center position, and a first position and a second position with a distance provided therebetween; obtaining a measurement point group including measurement points of the center position, the first position, and the second position; and determining a measurement point closest to the tip portion in the measurement point group based on positions of the measurement points in a second direction and selecting a position of the measurement point in a first direction as a selected position. When the measurement point group is obtained initially after the determination of the search starting position, the search starting position is set as the center position; and when the measurement point group is obtained after the selection of the selected position, the selected position is set as the center position. The distance is narrowed for every selection of the selected position.
US08907241B2 Sorting apparatus
An apparatus and a method for sorting particles into quality classes are disclosed. The apparatus comprises a measurement device (400) for determining at least one analytical property of said particles. A transport device (300) transports the particles past the measurement device. A sorting device (500) is operatively coupled to the measurement device and sorts the particles into at least two quality classes based on the analytical property. To achieve rapid and reliable transport, the transport device comprises a transport surface (310) configured to move in a transport direction. The transport surface has a plurality of perforations. The transport device further comprises a pump (130) for applying a pressure differential to these perforations, to cause particles fed to the transport device to be aspirated to the perforations and to be transported on the transport surface past the measurement device to the sorting device. In preferred embodiments, the transport surface is implemented as an endless transport belt or as a transport drum.
US08907239B2 Circuit interrupter and indicator apparatus
A circuit interrupter includes an indicator apparatus having a pair of movable elements and a connection apparatus that enables the pair of movable elements to be cooperable. One of the movable elements is connected with an indicator element that indicates an OPEN and/or a CLOSED condition of the circuit interrupter. A pair of engagement structures are situated on the pair of movable elements and enable the pair of movable elements to be engageable with one another. A biasing element extends between the pair of movable elements and is configured to absorb some of the kinetic energy of a trip event, which resists breakage of the indicator apparatus. The indicator element changes states when the set of separable contacts are at a relatively small amount of separation and does not require the set of separable contacts to reach the end of their travel before changing state.
US08907236B2 Floating stationary contact to create stable, low resistance contact joints
A floating contact assembly for use in a circuit breaker includes a contact, a floating member, a bearing element, a jaw member, and a flexible conductor. The floating member includes a joint surface and the contact is electrically connected to a surface of the floating member opposite the joint surface. The bearing element is configured to abut the joint surface of the floating member such that the floating member is configured to rotate about a first axis that passes through the bearing element. The jaw member is configured to electrically connect the floating contact assembly to an external electrical component and the flexible conductor electrically couples the jaw member to the floating member.
US08907234B2 Hybrid current switching device
A hybrid current switching device has a casing which includes a main current switch having first fixed and movable contacts connected in series with first and second terminals, a power switch device connected in parallel with the main current switch and switchable between an on-state and an off-state, a secondary current switch having second fixed and movable contacts and being connected in series with the power switch device, and a movable-contacts holding shaft on which the first and second movable contacts are mounted. The contacts-holding shaft is positioned inside the casing rotating around a rotation axis to move the movable contacts between a closed position where they are coupled with the corresponding fixed contacts and an open position where they are electrically separated therefrom. The first and second movable contacts are mounted on the rotating shaft with an angular offset relative to each other when in the open position.
US08907231B2 Display arrangement
An apparatus and a method are disclosed. The apparatus includes: a display panel having a length, a width and a depth; and a film including a first portion, extending along a surface of the display panel defined by the length and the width, and a second portion, extending at least partially along the depth, coupled to an electronic device housing.
US08907227B2 Multiple surface integrated devices on low resistivity substrates
The present invention relates to a device with portions of the device on plural substrate surfaces. The device includes a low resistivity substrate having first and second surfaces with a first electrically-conductive device component disposed over a first surface. An intermediate electrically-insulating layer may be disposed between the electrically-conductive component and the low resistivity substrate. A second electrically-conductive component is disposed over the second surface of the low resistivity substrate. A cavity formed in the low resistivity substrate is at least partially filled with a high resistivity material. One or more electrically-conducting pathways are formed in the high resistivity material electrically connecting the first electrically conductive component and the second electrically-conductive component to form a device. Exemplary devices include inductors, capacitors, antennas and active or passive devices incorporating such devices. Vertically integrated device systems can be formed using the device.
US08907225B1 Structures and methods related to detection, sensing, and/or mitigating undesirable structures or intrusion events on structures
A method and an apparatus for mitigating electrical failures caused by intrusive structures. Such structures can be tin whiskers forming on electrical circuits. In an illustrative embodiment, nano-capsules are filled with some type of insulative and adhesive fluid that is adapted to bind to and coat an intrusive structure, e.g., a whisker, making the whisker electrically inactive and thereby reducing the electrical faults that can be caused by the whisker. In another illustrative embodiment, randomly oriented nano-fibers having an elastic modulus higher than tin or any other whisker material is used to arrest a growth or movement of a whisker and further reduce a likelihood that a whisker can cause an electrical fault.
US08907222B2 Adjustable cover for conductors and insulators
A cover apparatus can cover an electrical insulator and an electrical conductor. The cover apparatus includes one or more leg sections for covering a portion of the electrical conductor. The cover apparatus includes a cover section coupled to the one or more leg sections and covering a portion of the electrical insulator. The cover section includes a body portion and an adjustable portion coupled to the body portion at a coupling location. The adjustable portion can be adjusted such that a dimension of the adjustable portion is adjusted according to a dimension of the electrical insulator. An example method of forming a cover apparatus for covering an electrical insulator and an electrical conductor is also provided.
US08907221B1 Reinforced intelligent cables
Provided are cables for transmitting media data between media transmitters and receivers. A cable includes an integrated circuit for performing this data transmission and, in certain embodiments, various other functions. The integrated circuit may be enclosed in a base member used to support one of the connectors of the cable. The cable also includes a flexible member extending between this base member and another connector. A portion of the cable protrudes into the base member and makes electrical connections to conductive points of the integrated circuit or, more specifically, to conductive points on a connection pad of the circuit. The cable is rigidly supported and mechanically secured to the base member to preserve these electrical connections, particularly when mechanical stress is applied to the flexible member. In certain embodiments, the base member includes one or more notch members and/or enclosure members to ensure this support.
US08907220B2 High-speed card cable
Techniques described herein generally relate to ground planes. In some examples, an electrical cable is described that can include multiple signal lines. The multiple signal lines can be arranged to extend along a length of the electrical cable. A ground plane can be spaced apart from the multiple signal lines. The ground plane can include a mesh structure and an electrically conductive layer that is arranged to coat the mesh structure. The mesh structure can include multiple resin fibers.
US08907216B2 Cable port protection apparatus
A cable port protection apparatus includes a frame that is configured to be secured to a housing of an electronic device, and a cable retention mechanism attached to the frame that is configured to prevent unintentional removal of a cable from a cable port of the electronic device. The cable retention mechanism includes a pair of spaced-apart arms extending outwardly from the frame to define a cable receiving space. A gate is operably associated with the spaced-apart arms and is movable by a user between open and closed positions. When in an open position, a cable can be inserted by a user through the cable receiving space and connected to a cable port. When in a closed position, the cable is prevented by the gate from becoming disconnected from the cable port and from exerting potentially damaging forces on the cable port.
US08907213B2 Electric junction box
An electric junction box for preventing brackets, while inclined to each other, from being fastened together, comprises a first cassette block and a second cassette block. Brackets of the first block and the second block are stacked onto each other, a bolt is passed through each of the through holes, and the blocks are fastened together. A metal collar formed tubular in nearly eclipse cross-sectional shape is also attached to inner surfaces of the through holes formed into nearly ellipse cross-sectional shape. Each of the collars is attached to each of the brackets so that long axes of the collars intersect to each other.
US08907212B2 Junction box with improved heat dissipation
A junction box includes a cable connecting box and a cover covering the cable connecting box. The cable connecting box includes an insulative block, a plurality of contacting foils retained in the insulative block and a plurality of diodes. Each diode connects with two neighborly contacting foils. The contacting foils are insert-molded with the insulative block. Based on thermal radiation properties of the plastic material is superior to that of the metal material, as the contacting foils transfer the heat to the insulative block, the insulative block would deliver the heat to the cable connecting box, then the heat would be delivered to the cover. Such that, the heat dissipates outside quickly from the junction box.
US08907210B2 Semiconductor material and its application as an absorber material for solar cells
This invention describes a semiconductor material of general formula (I) Me12Me21-xMe3xMe4(C11-yC2y)4, in which x stands for a numeric value from 0 to 1, and y stands for a numeric value of 0 to 1, as well as its use as an absorber material in a solar cell. The metal Mel is a metal which is selected from the metals in group 11 of the periodic table of the elements (Cu, Ag or Au). The metals Me2 and Me3 are selected from the elements of the 12th group of the periodic table of elements (Zn, Cd & Hg). The metal Me4 is a metal which is selected from the 4th main group of the periodic table of elements (C, Si, Ge, Sn and Pb). The non-metals C1 and C2 are selected from the group of chalcogenides (S, Se and Te).
US08907207B2 Solar cell module
A solar cell module according to an embodiment includes a solar cell device and a support structure supporting the solar cell device. The solar cell device is a belt-like solar cell device including first portions arranged in one direction such that major surfaces thereof face each other, and a second portion interposed between the first portions. The edges of the first portions that correspond to a pair of long sides of the solar cell device are parallel to each other. Two adjacent first portions incline forwardly and backwardly with respect to the one direction. The second portion includes one or more planar or curved surfaces to connect the two adjacent first portions to each other.
US08907204B2 Thin film photoelectric conversion device and method for manufacturing the same
Provided is a thin film photoelectric conversion device with maximized output characteristic, which is achieved by improving an uneven current value of a photoelectric conversion cell caused by an uneven film thickness and an uneven film quality of a photoelectric conversion semiconductor layer, which may be generated in scaling up an integrated-type thin film photoelectric conversion device. The thin film photoelectric conversion device includes: a substrate, a transparent electrode layer, a photoelectric conversion unit, and a back electrode layer. An increasing rate ΔZt of the film thickness Zt of the transparent electrode layer along X and an increasing rate ΔZs of the film thickness Zs of the photoelectric conversion unit along X have different signs, wherein one line segment in a parallel direction to a main surface of the substrate is taken as X″.
US08907197B2 Performance information processing apparatus, performance information processing method, and program recording medium for determining tempo and meter based on performance given by performer
A performance-information processing apparatus processes performance information entered thereto. When the performance information is entered in a time interval between (i) a starting time point, at which performance information of one note starts entering and (ii) a first timing, that is a certain time after another performance information of a note has been entered after the performance information of said one note was entered, a tempo determining unit determines a tempo of the performance information, based on the performance information entered in the time interval, and a meter determining unit which determines a meter of the performance information based on the tempo determined by the tempo determining unit.
US08907194B2 System for computer-assisted interpretation of pre-recorded music
The invention relates to a computer-aided prerecorded-music-interpretation system. The system comprises at least one musical actuator (A1, A2) actuatable by an interpreting artist user, memory means for storing musical information (MM) relating to the score of a piece of music to be interpreted by the user, and means for transmitting the musical information to an electronic/computerized device (A4) adapted for producing audio signals on the basis of the musical information received. The memory (MM) for the musical information defines the totality of the musical events (EM) constituting the piece of music to be interpreted. The invention is usable in the field of prerecorded-music interpretation.
US08907184B1 Soybean cultivar 90559121658
A soybean cultivar designated 90559121658 is disclosed. Embodiments of the invention include the seeds of soybean 90559121658, the plants of soybean 90559121658, to plant parts of soybean 90559121658, and methods for producing a soybean plant produced by crossing soybean 90559121658 with itself or with another soybean variety. Embodiments of the invention include methods for producing a soybean plant containing in its genetic material one or more genes or transgenes and the transgenic soybean plants and plant parts produced by those methods. Embodiments of the invention also relate to soybean cultivars, breeding cultivars, plant parts, and cells derived from soybean 90559121658, methods for producing other soybean cultivars, lines or plant parts derived from soybean 90559121658, and the soybean plants, varieties, and their parts derived from use of those methods. Embodiments of the invention further include hybrid soybean seeds, plants, and plant parts produced by crossing 90559121658 with another soybean cultivar.
US08907181B1 Soybean cultivar 21239
Disclosed is the seed of a novel soybean cultivar, designated 21239, a sample of which is deposited under ATCC Accession No. PTA-121150. Also disclosed are plants, or parts thereof, grown from the seed of the cultivar, plants having the morphological and physiological characteristics of the 21239 cultivar, and methods of using the plant or parts thereof in a soybean breeding program.
US08907177B2 Soybean variety A1037391
The invention relates to the soybean variety designated A1037391. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1037391. Also provided by the invention are tissue cultures of the soybean variety A1037391 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1037391 with itself or another soybean variety and plants produced by such methods.
US08907175B2 Soybean variety A1036609
The invention relates to the soybean variety designated A1036609. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1036609. Also provided by the invention are tissue cultures of the soybean variety A1036609 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1036609 with itself or another soybean variety and plants produced by such methods.
US08907174B2 Soybean variety A1036466
The invention relates to the soybean variety designated A1036466. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1036466. Also provided by the invention are tissue cultures of the soybean variety A1036466 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1036466 with itself or another soybean variety and plants produced by such methods.
US08907171B2 Soybean variety A1035334
The invention relates to the soybean variety designated A1035334. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1035334. Also provided by the invention are tissue cultures of the soybean variety A1035334 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1035334 with itself or another soybean variety and plants produced by such methods.
US08907170B2 Soybean variety A1035315
The invention relates to the soybean variety designated A1035315. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1035315. Also provided by the invention are tissue cultures of the soybean variety A1035315 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1035315 with itself or another soybean variety and plants produced by such methods.
US08907166B2 Soybean variety A1036233
The invention relates to the soybean variety designated A1036233. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1036233. Also provided by the invention are tissue cultures of the soybean variety A1036233 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1036233 with itself or another soybean variety and plants produced by such methods.
US08907161B1 Maize inbred PH1C2K
A novel maize variety designated PH1C2K and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1C2K with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1C2K through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1C2K or a locus conversion of PH1C2K with another maize variety.
US08907154B2 Sanitary napkins with hydrophobic lotions
A catamenial device comprising a liquid pervious topsheet, the topsheet having an inner surface oriented toward the interior of the absorbent article and an outer surface oriented toward the body of the wearer when the absorbent article is being worn. At least a portion of the topsheet outer surface comprises an effective amount of a lotion coating which is semi-solid or solid at about 25° C. and which is partially transferable to the wearer's body. The lotion coating comprises from about 60 to about 99.9% of a carrier comprising a petroleum based hydrocarbon and lower molecular weight glycols or polyols and from about 0.2 to about 65% of a fatty alcohol with a melting point from about 450 C to about 110° C. A backsheet is joined to the topsheet and an absorbent core is disposed between the topsheet and the backsheet.
US08907153B2 Adhesive peel-forming formulations for dermal delivery of drugs and methods of using the same
The present invention is drawn to adhesive peel-forming formulations for dermal delivery of a drug. The formulation can include a drug, a solvent vehicle, and a peel-forming agent. The solvent vehicle can include a volatile solvent system having one or more volatile solvent, and a non-volatile solvent system having one or more non-volatile solvent, wherein the non-volatile solvent system has a solubility for the drug that is within a window of operable solubility for the drug such that the drug can be delivered at therapeutically effective rates over a sustained period of time. The formulation can have a viscosity suitable for application to a skin surface prior to evaporation of the volatile solvents system. When applied to the skin, the formulation can form a solidified peelable layer after at least a portion of the volatile solvent system is evaporated.
US08907149B2 Process for the production of chlorinated propenes
Processes for the production of chlorinated propenes are provided. The present processes make use of a feedstream comprising 1,2-dichloropropane, a by-product in the production of chlorohydrin, as a low cost starting material, alone or in combination with 1,2,3-trichloropropane. Selectivity of the process is enhanced over conventional processes employing successive chlorinations and/or dehydrochlorinations, by conducting at least one chlorination in the presence of an ionic chlorination catalyst. The present processes may also generate anhydrous HCl as a byproduct that can be removed from the process and used as a feedstock for other processes, providing further time and cost savings.
US08907139B2 Process for acetal removal in the purification of a crude ethanol product
Recovery of ethanol from a crude ethanol product obtained from the hydrogenation of acetic acid. Separation and purification processes of the crude ethanol products are employed to allow recovery of ethanol and hydrolyze acetal impurities by the addition of an acid stream.
US08907137B2 Epoxy resin production
A process comprising contacting a polyhydric phenol or a polyaliphatic alcohol with an epihalohydrin in the presence of a catalyst comprising a Schiff base metal complex is disclosed.
US08907123B2 Process for the acetoxylation of olefins in the gas phase
Yield and selectivity of olefin acetoxylation are improved through the use of successive catalyst zones of different reactivities, the successive zones contained in one or more reaction tubes arranged is parallel.
US08907121B2 Methyl methacrylate purification process
A process for purifying methyl methacrylate (MMA) is described. The process involves contacting liquid MMA having impurities therein with a sulphonic acid resin, in the presence of formaldehyde or a suitable source of methylene or ethylene of formula I. R5 and R6 are independently selected from C1-C12 hydrocarbons or H; X is either O or S; n is an integer from, 1 to 100; and m is 1 or 2: The compound of formula I may be suitable source of formaldehyde.
US08907120B2 Perfluoropolyether-containing compounds with oxalylamino groups
Compounds containing at least one perfluoropolyether segment and at least two oxalylamino groups as well as methods of making these compounds are described. The compounds can be polymeric materials or can be used in the preparation of various copolymeric materials by reaction with compounds having at least two primary or secondary amino groups.
US08907119B2 Process for preparing mercaptoalkyl carboxylates
In the acid-catalyzed esterification of mercaptoalkyl alcohols by means of carboxylic acids to form mercaptoalkly carboxylates, formation of undesirable, usually sparingly soluble by-products usually occurs. The process of the invention in the absence of acid catalysts avoids the formation of such by-products. Particularly when the esterification of the invention is carried out as reactive distillation using reactive column and residence vessel, good degrees of conversion can also be obtained without acid catalyst and at the same time the formation of the by-products can be largely avoided.
US08907117B2 Anti-tumor and anti-inflammatory dicinnamoyl-glycerol esters and their analogues
Synthetic dicinnamate compounds and their analogs are disclosed that exhibit anti-tumor activity and/or an anti-inflammatory activity, and have beneficial activity principally in destroying cancer cells. Furthermore, methods for the extraction of the extracts are disclosed.
US08907115B2 Synthesis and characterization of first row transition metal complexes containing α-keto hydrazonate ligands as potential precursors for use in metal film deposition
A compound that is useful for forming a metal by reaction with a reducing agent is described by formula (I): wherein M is a metal selected from Groups 3 through 12 of the Periodic Table; R1 and R2 are each independently H or C1-C6 alkyl; and R3 is H or C1-C8 alkyl.
US08907112B2 Method for preparing epoxide
A method for producing an epoxide is disclosed. The method includes performing a reaction of an olefin compound and an oxidant by using a titanium-silicon molecular sieve as a catalyst, in the presence of a silicon oxide containing an alkaline earth metal as a coagent. The selectivity and yield of epoxide are increased by using a silicon oxide containing an alkaline metal as a coagent.
US08907111B2 Neuraminidase inhibitor compounds, compositions and methods for the use thereof in anti-viral treatments
Compounds having a structure of Formula I and compositions comprising these compounds are provided. Uses of such compounds and compositions are provided for treatment or prophylaxis of viral infection. In particular, compounds and compositions may be for use in the treatment or prophylaxis of viral influenza.
US08907108B2 P-type organic semiconductor material and optoelectronic device utilizing the same
Disclosed is a p-type organic semiconductor material having the formula: Each Con is the same and consists of a conjugated oligomer. Each EW is the same and consists of an electron withdrawing group. The p-type organic semiconductor material can be applied in an active layer of an optoelectronic device, such as an organic solar cell, an organic light-emitting diode, or an organic thin-film transistor.
US08907104B2 Synthesis of enone intermediate
The tetracycline class of antibiotics has played a major role in the treatment of infectious diseases for the past 50 years. However, the increased use of the tetracyclines in human and veterinary medicine has led to resistance among many organisms previously susceptible to tetracycline antibiotics. The recent development of a modular synthesis of tetracycline analogs through a chiral enone intermediate has allowed for the efficient synthesis of novel tetracycline analogs never prepared before. The present invention provides a more efficient route for preparing the enone intermediate.
US08907100B2 Lansoprazole compound and novel preparation method thereof
A process for purifying lansoprazole comprises 1) loading crude lansoprazole material onto a macroporous resin column; 2) concentrating the eluate from the column in a crystallization vessel by vacuum; 3) seeding lansoprazole crystal; 4) crystallizing the lansoprazole; 5) separating the precipitated crystals. The process especially has large processing capacity, can be carried out continuously and therefore suitable for industrial production, improving the quality of formulated products and reducing side effects.
US08907099B2 Nitrocatechol derivatives as COMT inhibitors
New compounds of formula I are described. The compounds have potentially valuable pharmaceutical properties in the treatment of some central and peripheral nervous system disorders.
US08907097B2 Pyrido[4,3-b]indoles containing rigid moieties
This disclosure is directed to pyrido[4,3-b]indoles having rigid moieties. The compounds in one embodiment are pyrido[4,3-b]indoles having an unsaturated hydrocarbon moiety. The compounds in another embodiment are pyrido[4,3-b]indoles having a cycloalkyl, cycloalkenyl or heterocyclyl moiety. Pharmaceutical compositions comprising the compounds are also provided, as are methods of using the compounds in a variety of therapeutic applications, including the treatment of a cognitive disorder, psychotic disorder, neurotransmitter-mediated disorder and/or a neuronal disorder.
US08907090B2 Processes for preparing different forms of (S)-(+)-Clopidogrel bisulfate
The invention provides improved processes for the preparation of hydrated form of (S)-(+)-Clopidogrel bisulfate as well as improved processes for the preparation of form-I and form-II of (S)-(+)-Clopidogrel bisulfate.
US08907089B2 Fused heterocyclic ring derivative and use thereof
The present invention provides a fused heterocycle derivative having a strong Smo inhibitory activity, and use thereof.Specially, the present invention relates to a compound represented by the formula wherein each symbol is as defined in the specification, or salt thereof, and a medicament containing the compound or a prodrug thereof, which is an Smo inhibitor or an agent for the prophylaxis or treatment of cancer.
US08907084B2 Process for the preparation of 2-(2-aminoethoxy) ethanol (2AEE) and morpholine with 2AEE: morpholine >3
The invention relates to a process for the production of 2AEE with selectivity towards 2AEE being significantly higher i.e. the ratio of 2AEE:morpholine >3. DEG and Ammonia are reacted in a continuous mode in hydrogen atmosphere in the presence of a catalyst at temperature of 150° C. to 250° C. and pressure of 10 Bar to 20 Bar, the products being separated by distillation. The catalyst used is metal and its oxide or metal oxide on silica or alumina support. The molar ratio of ammonia:DEG is >20 and the molar ratio of hydrogen:DEG is >1, preferably 1-30. The reactants are optionally fed in a downward flow mode. The catalyst charged into the reactor has metal and its oxide or metal oxide equivalent to a metal content of 10% to 70% on the support.
US08907082B2 1,2-bis-(4,7-dimethyl-1,4,7-triazacyclonon-1-yl)-ethane and intermediate for the synthesis of same
The present invention provides improved processes for the synthesis of 1,4-ditosyl-1,4,7-triazacyclonone, comprising deprotecting a compound of formula (C): wherein P is tosylate or arylsulfonate, with an acidic medium to form 1,2-bis(1,4,7-triazacyclonon-1-yl)-ethane; and subsequently adding formaldehyde and formic acid to the acidic medium to form 1,2-bis-(4,7-dimethyl-1,4,7-triazacyclonon-1-yl)-ethane (Me4-DTNE). The syntheses of intermediates are also disclosed.
US08907081B2 Long wavelength absorbing porphyrin photosensitizers for dye-sensitized solar cells
A long wavelength absorbing porphyrin/metalloporphyrin molecule is provided, made up of a porphyrin macrocycle and an anchor group for attachment to a substrate. A molecular linking element is interposed between the porphyrin macrocycle and the anchor group. The porphyrin/metalloporphyrin molecule also includes an (aminophenyl)amine group, either N,N-(4-aminophenyl)amine or N-phenyl-N-(4-aminophenyl)amine, where an amino moiety of the 4-aminophenyl group is derivatized by an element such as hydrogen, haloalkanes, aromatic hydrocarbons, halogenated aromatic hydrocarbons, heteroarenes, halogenated heteroarenes, or combinations of the above-mentioned elements.
US08907075B2 Compositions and methods for gene silencing
Compositions and methods for modulating the expression of a protein of interest are provided.
US08907071B2 Toxin peptide therapeutic agents
Disclosed is a DNA encoding a composition of matter of the formula (X1)a—(F1)d—(X2)b—(F2)e—(X3)c  (I) and multimers thereof, in which F1 and F2 are half-life extending moieties, and d and e are each independently 0 or 1, provided that at least one of d and e is 1; X1, X2, and X3 are each independently -(L)f-P-(L)g-, and f and g are each independently 0 or 1; P is a ShK peptide analog of no more than about 80 amino acid residues in length; L is an optional linker; and a, b, and c are each independently 0 or 1, provided that at least one of a, b and c is 1. A DNA encoding the ShK peptide analog is disclosed. Also disclosed are an expression vector comprising the DNA, and a host cell comprising the expression vector.
US08907070B2 Glycolipids of branched chain alkyl oligosaccharides for liquid crystal and related applications
Glycolipids of branched chain alkyl oligosaccharides include a primary alcohol branched in the 2-position and an oligosaccharide, covalently bond to the alcohol in either α- or β-linkage (shown in Formula I and Formula II). These compounds show phase behavior not found for the corresponding straight chain counterparts. The properties involve an ambient temperature liquid crystalline appearance and thermotropic liquid crystal phase polymorphism. The formation of cubic phases is considered most interesting with respect to life science applications, e.g. liposomes for drug delivery. Depending on the choice of sugar head group and alkyl tail, various levels of water miscibility may be adjusted to meet applications requirements (complete solubility for emulsifier applications, e.g. cosmetic creams, to limited water swelling only, e.g. for the preparation of artificial membranes). The closed structural relationship to natural lipids also makes branched chain alkyl oligosaccharides valuable subjects for biochemical investigations, e.g. membrane studies.
US08907068B2 Anti-IL-20 antibodies and binding partners and methods of using in inflammation
The present invention relates to blocking the activity of IL-20 polypeptide molecules. IL-20 is a cytokine that is involved in inflammatory processes and human disease. IL-20RA/IL-20RB is a common receptor for IL-20. The present invention includes anti-IL-20 antibodies and binding partners, as well as methods for antagonizing IL-20 using such antibodies and binding partners.
US08907066B2 Antibody fusion proteins with a modified FcRn binding site
Disclosed are antibody fusion proteins with a modified FcRn binding site and nucleic acid molecules encoding them. The antibody fusion protein include two polypeptide chains, wherein the first polypeptide chain includes a biologically active molecule linked to at least a portion of an immunoglobulin constant region. The second polypeptide chain includes at least a portion of an immunoglobulin constant region. One of the polypeptide chains includes a mutation in the FcRn binding site that reduces binding to FcRn. Also disclosed are methods of producing the fusion proteins and methods of using the fusion proteins for treating diseases and conditions alleviated by the administration of the fusion proteins.
US08907064B2 Modified human four helical bundle polypeptides and their uses
Modified human four helical bundle (4HB) polypeptides and uses thereof are provided.
US08907057B2 Peptides that target dorsal root ganglion neurons
The present invention concerns methods and compositions that employ peptides that target dorsal root ganglion (DRG) neurons. In particular, the peptides are used to target therapeutic agents, such as proteins, liposomes, or viral particles comprising therapeutic polynucleotides, to one or more peripheral neuropathies or neuropathic pain, for example. In particular cases, the peripheral neuropathies or neuropathic pain is caused directly or indirectly by DRG neuronopathy.
US08907055B2 Mutant sox proteins and methods of inducing pluripotency
There is presently provided mutant Sox2, Sox7 and Sox17 proteins that have acquired or increased ability to induce pluripotency in a partially differentiated or fully differentiated cell. Sox7 and Sox17 are mutated to resemble in part Sox2, or Sox2 is mutated to resemble in part Sox7 or Sox17. In one aspect, the Oct4 contact interface of Sox7 or Sox17 is mutated. In another aspect, the high mobility group (HMG) of Sox2 is fused to the C-terminal activation domain of Sox7 or Sox17. Methods relating to inducing pluripotency using a mutant Sox2, Sox7 or Sox17 protein are also provided.
US08907050B2 Polymeric additive for strength, deformability, and toughness enhancement of cemetitious materials and composites
Methods are generally provided for forming a polymer-cement composite. In one embodiment of the method, a plurality of dopamine monomers is dispersed in a buffer solution. Polymerization of the dopamine monomers can then be initiated, and a cement-sand mixture can be added to the buffer solution to form a composite mixture. Finally, the composite mixture can be cured to form a polymer-cement composite. Polymer-cement composites are also generally provided that, in one embodiment, include cement, sand, and poly(dopamine), with the polymer-cement composite having a compressive strength of 8000 psi.
US08907048B2 Production method of polycarbonate resin
The present invention is a production method of a polycarbonate resin, including a step of performing melt polycondensation by continuously feeding a dihydroxy compound (A) having a predetermined moiety in a part of the structure and a carbonic acid diester each in a liquid state to a reactor, wherein the residence time from liquefaction of the dihydroxy compound to its feeding to a reactor is from 0.1 to 10 hours.
US08907047B2 Water-soluble polymer and water-soluble nanoparticle composite
A water-soluble nanoparticle complex has a plurality of accumulated nanoparticles and has excellent uniformity and stability by forming a complex of nanoparticles using a water-soluble polymer and which allows for use of nanoparticles in biochemical applications.
US08907037B2 Preparation of lignocellulosic products
A method of preparing a polymeric methylene diphenyl diisocyanate-polydialkylsiloxane resin by mixing at a temperature between 25° C. and 100° C.: (i) a polymeric methylene diphenyl diisocyanate with (ii) a polydialkylsiloxane selected from hydroxyalkyl dialkyl terminated polydialkylsiloxane having a viscosity of from 5 to 500 000 cSt at 25° C. or (hydroxyalkoxy)alkyl dialkyl terminated polydialkylsiloxane having a viscosity of from 5 to 500 000 cSt at 25° C. in an amount such that from 1 to 99% by weight of the total weight of (i) and (ii) is component (ii), optionally in the presence of a solvent; and subsequently extracting the solvent, if present.
US08907034B2 Comb architecture olefin block copolymers
Embodiments of the invention provide a comb architecture olefin block copolymer, a method of making the comb olefin block copolymer and blends comprising the comb olefin block copolymer.
US08907028B2 Aqueous mixtures comprising aminoalkyl-containing polyorganosiloxanes and silicone resins
Aqueous emulsions of organopolysiloxanes functionalized with a limited amount of aminoalkyl-functional end groups and silicone resins are storage stable, yet capable of adequate crosslinking upon application to substances to be hydrophobicized.
US08907024B2 Curable composition
An object of the present invention is to provide a curable composition that provides high hardness and can be used in adhesives and coating agents. This object can be achieved by a curable composition containing: 100 parts by weight of a reactive silyl group-containing organic polymer (A) that has a number average molecular weight of 2,000 to 6,000 and contains 1.3 to 5 reactive silyl groups per molecule; and 0 to 40 parts by weight of a plasticizer (C). This curable composition is suitable for flooring adhesives and tile adhesives, which require high hardness.
US08907021B2 Polyacrylic acid (salt)-type water absorbent resin and method for producing of same
Disclosed is a method for producing a water absorbent resin, by which a surface-crosslinked water absorbent resin having excellent physical properties can be efficiently obtained at low cost, while assuring high productivity. When the production scale is increased to a continuous production at 1 t/hr or more, the physical properties are improved and stabilized (for example, standard deviation of the physical properties is reduced) by a surface-crosslinking treatment, and the absorption against pressure (AAP) and liquid permeability (SFC) are further improved. Specifically disclosed is a method for producing a water absorbent resin, which is characterized in that the stirring shaft of the continuous mixing apparatus for the surface-crosslinking agent is heated during the mixing step of the surface-crosslinking agent or that the continuous mixing apparatus for the surface-crosslinking agent is operated at a pressure that is reduced relative to the ambient pressure and a gas flow is passed through the mixing apparatus during the mixing of the surface-crosslinking agent so that the gas flow in the mixing apparatus is 40° C. or more (when defined with respect to the gas temperature at the exit).
US08907018B2 Rotomolding resin
Resins suitable for rotomolded articles comprise a bimodal polyethylene copolymer comprising from 0.1 to 5 weight % of one or more C6-8 alpha olefins and the balance ethylene, comprising from 20 to 50 weight % of a higher molecular weight polymer component having an Mw greater than 120,000 and correspondingly from 80 to 50 weight % of a lower molecular weight polymer component having an Mw less than 100,000 having a density greater than 0.942 g/cc [but less than 0.965 g/cc] and a bent strip ESCR as determined by ASTM D 1693 in 100% Igepal® CO-630 (ethoxylated nonylphenols) for conditions A and B of greater than 1000 hours. The resulting articles have a very good balance of properties and significant ESCR.
US08907016B2 Dispersing agent containing copolymer mixture
The invention relates to a polymer composition containing 5 to 95% by weight of a copolymer H and 2 to 60% by weight of a copolymer K, the copolymers H and K each having polyether macromonomer structural units and acid monomer structural units, which are present in the copolymers H and K in each case in a molar ratio of 1:20 to 1:1, and at least 20 mol % of all structural units of the copolymer H and at least 25 mol % of all structural units of the copolymer K being present in each case in the form of acid monomer structural units, the polyether macromonomer structural units of the copolymer H having side chains containing in each case at least 5 ether oxygen atoms, the number of ether oxygen atoms per side chain of the polyether macromonomer structural units of the copolymer H varying in such a way that the corresponding frequency distribution diagram, in which the number of ether oxygen atoms per side chain of a polyether macromonomer structural unit is plotted along the abscissa and the associated frequency for the copolymer H is plotted along the ordinate, contains at least 2 maxima.
US08907014B2 Silane terminated polymer for coating, adhesives, sealant and elastomer applications
A copolymer-filled crosslinkable silane-terminated polymer having at least one crosslinkable silyl group in each molecule is provided. The copolymer-filled crosslinkable silane-terminated polymer is the reaction product of a copolymer-filled polyol and an isocyanate capped hydrosilylated polymer. The isocyanate capped hydrosilylated polymer is the reaction product of at least one isocyanate and a hydrosilylated polymer. The hydrosilylated polymer is the reaction product of a polymer having at least one unsaturated group and at least one alcoholic group in each molecule and a compound having a hydrogen-silicon bond and a crosslinkable silyl group in each molecule. The copolymer-filled crosslinkable silane-terminated polymers exhibit improved modulus and tensile strength properties while maintaining elongation properties.
US08907009B2 Method for producing polymers with a neutral color tone
A method is disclosed for producing polymers with a neutral color tone, wherein a blue and red dye are added before entry into the last polyreaction stage, wherein adjustment of a neutral color tone of the polymer, using a total dye concentration in the polymer of no more than 3 ppm and a proportion of the blue dye in the resulting dye mixture of at least 50% by weight, occurs through independent adjustment of a and b color values in the Lab color space by determination of a and b color values of the polymer without addition of dyes, establishment of the total dye concentration depending on the b-value shift to be achieved, establishment of the required mixture ratio of the colors red and blue depending on the a-value shift to be achieved, and metering of the established content of dye mixture into the reaction mixture.
US08907007B2 Process for painting substrates
The invention relates to a process for painting substrates comprising the following steps: 1. applying a coating composition to an optionally pre-coated substrate and 2. hardening the applied coating composition, wherein the coating composition comprises: A) at least one binder having functional groups containing active hydrogen, B) at least one polyisocyanate cross-linking agent having free isocyanate groups and C) at least one urethane compound having at least two —O—CO—NH— groups, wherein the urethane compound is substantially free from functional groups which are capable of entering into a cross-linking reaction with components A) and/or B) and wherein the hardening is carried out under conditions such that the component C) does not contribute to the cross-linking of the applied coating composition by chemical reaction.
US08907005B2 Powerfeed polymers having improved block resistance performance
The present invention provides emulsion copolymers and coating compositions containing the same having improved room temperature and hot block resistance in coatings wherein the copolymers have a broad measured glass transition temperature and are the copolymerization product of a vinyl monomer composition A and a softer vinyl monomer composition B having a Hansch parameter of at least 3.2, and containing one or more vinyl monomer M, such that each of which vinyl monomer(s) M would when homopolymerized provide a homopolymer having a measured Tg of 20° C. or less, such as, for example, 2-ethylhexyl acrylate. In addition, the present invention provides methods for making the emulsion copolymers by a powerfeed process comprising feeding vinyl monomer composition A into a reactor from a feed vessel while feeding, simultaneously or after a delay, vinyl monomer composition B into the feed vessel while polymerizing the monomers in the reactor.
US08907000B2 Organoclay-polyurea nanocomposites
A nanocomposite having a nanomaterial dispersed into a polymer matrix, in one embodiment exfoliated nanoclay dispersed in a polyurea matrix. A method of making PU-nanocomposites for coatings for improved mechanical properties, in one embodiment the method comprises obtaining and treating a nanomaterial, dispersing the nanomaterial into a pre-polymer matrix, mixing the pre-polymer matrix under heating to form a coating; and depositing the coating on a substrate.
US08906997B2 Multivinyl siloxane oligomer-based polymer dispersions and methods of preparing and using the same
Multivinyl siloxane oligomer-based compositions and methods for their preparation and use are described herein. The multivinyl siloxane oligomer-based compositions can be prepared as aqueous polymer dispersion. The aqueous polymer dispersions can include water and a polymer derived from at least one multivinyl siloxane oligomer having an Si—O—Si backbone and at least one alkoxy group and one or more additional monomers. Further described herein are products including the aqueous polymer dispersions and methods for their preparation and use.
US08906996B2 Spherical, amorphous calcium carbonate particles
Stabilized, spherical, amorphous calcium carbonate particles having a mean particle diameter in the range from 0.05 μm to 2.0 μm and a water content of at most 5.0 wt % measured as residual moisture at 200° C., wherein the calcium carbonate particles comprise at least one substance which has a molar mass greater than 100 g/mol and satisfies the formula R—Xn, wherein the radical R represents a radical comprising at least one carbon atom, the radical X represents a group which comprises at least one oxygen atom and at least one carbon atom, sulphur atom, phosphorus atom and/or nitrogen atom and n preferably constitutes a whole number in the range from 1 to 20, the proportion of crystalline calcium carbonate is less than 30 wt %, and the specific surface area of the calcium carbonate particles is at most 20 m2/g.
US08906995B2 Polymer compositions, method of manufacture, and articles formed therefrom
An impact resistant polycarbonate composition having improved resistance to polymer degradation comprises an aromatic polycarbonate in admixture with an elastomer-modified graft copolymer that is the product of an emulsion polymerization process, wherein composition is a product of compounding the aromatic polycarbonate and the elastomer-modified graft copolymer in the presence of a buffer comprising a potassium salt of phosphoric acid.
US08906993B2 Coating composition containing siloxane resin
[Object]To provide a coating composition excellent in coatability and free from viscosity increase caused by degradation over time, and also to provide a hardened film-formation method employing that.[Means]The present invention provides a coating composition comprising: a siloxane resin having silanol groups or alkoxysilyl groups, and a polyol having hydroxyl groups at both ends of a straight 2 to 5 carbon atom hydrocarbon chain. This coating composition enables to form a hardened film of high transparency, of high insulation and of low dielectricity.
US08906987B2 UV barrier film
Transparent polypropylene film comprising at least two UV-absorbing additives, a first additive being a non-aggregated inorganic material present in the film composition in an amount of from 0.1 to 5.0% by weight, and a second additive comprising an organic material selected from triazines, hindered amines, oxanilides, cyanoacrylates, benzotriazoles and/or benzophenones and present in the film in an amount of less than 2.0% by weight and wherein when both benzotriazole(s) and benzophenone(s) are present in the film, the ratio of benzotriazole(s) to benzophenone(s) is above 0.5.
US08906984B2 Synthesis of metal and metal oxide nanoparticle-embedded siloxane composites
Metal/metal oxide nanoparticle-embedded polymer films were synthesized in situ wherein the polymerizing agent was utilized for both reduction and polymerization (such as curing). This in situ method avoids the use of any external reducing agent/stabilizing agent and leads to a uniform distribution of nanoparticles in the polymer matrix. In some embodiments, additional heating can be utilized to form the nanoparticles embedded in the polymer film.
US08906972B1 Aqueous two phase (ATPSs) of pH-responsive poly(phosphonate-alt-sulfur dioxide) with PEG
An aqueous two-phase system (ATPS) containing a poly(oxyethylene) (POE) and a poly[sodium (diallylamino)alkylphosphonate-alt-sulfur dioxide] form a pH-responsive dianionic polyelectrolyte (DAPE). The two polymers form ATPS's at low concentrations, where the addition of HCl changes the charge types and their densities on the polymer chains.
US08906965B2 Anti-inflammatory quinic acid derivatives for radioprotection/radiomitigation
Disclosed are methods of use of analogs of quinic acids or shikimic acids for protection from the harmful effects of radiation when administered either prior to radiation exposure, after radiation exposure, or both. These methods are useful for treating humans and animals exposed to radiation and at risk for radiation sickness and/or death as the result of radiation exposure.
US08906960B2 Synergistic effect of tocotrienols and curcumin
A transdermal fluid is provided wherein the main ingredient is tocotrienol and curcumin is added to enhance the anti-cancer effects of tocotrienols. The composition is useful for the treatment or prevention of a cancer, a tumor or an inflammatory disorder, particularly breast cancer.
US08906958B2 Compounds and mixtures for influencing inflammatory states
The invention relates to certain compounds, salts of these compounds and mixtures containing or consisting of two or more such compounds, two or more such salts or one or more such compounds and one or more such salts, each for use in a method for the prophylaxis and/or treatment of inflammation, in particular of inflammation of the skin.
US08906957B2 Polyphenol-rich extract from plant material
A process is provided for preparing (1) a first composition obtained by extracting a plant material with a single phase mixture of water and at least a first organic solvent under agitation so as to obtain a first extract rich in polyphenol oligomers, wherein the first composition is the first extract, and (2) a second composition obtained by extracting at least a portion of the first extract with a biphasic mixture of water and at least a second organic solvent under agitation so as to obtain a second extract rich in polyphenol monomers, dimers, and trimers, wherein the second composition is the second extract. Food products, mendicants, and cosmetics containing the first composition or the second composition are also provided.
US08906952B2 Indole derivative or pharmaceutically acceptable salt thereof, preparation method thereof, and pharmaceutical composition for preventing or treating metabolic diseases containing same as active ingredient
The present invention relates to an indole derivative, The indole derivative according to the present invention effectively inhibits the activity of diacylglycerol acyltransferase (DGAT) which induces metabolic diseases, such as obesity, diabetes, hyperlipidemia, or fatty liver and the like in lipid metabolism, thereby effectively regulating lipid metabolism and energy metabolism, and thus can be useful in pharmaceutical compositions for preventing or treating metabolic disease.
US08906949B2 Orally disintegrating tablets of zolmitriptan and process for preparing the same
Silicon dioxide free orally disintegrating tablet formulations of zolmitriptan or a pharmaceutically acceptable salt thereof having magnesium carbonate heavy and sodium stearyl fumarate with one or more pharmaceutically acceptable excipients and a process for preparing such a formulation and its use in the treatment of migraines.
US08906944B2 Compounds as tyrosine kinase modulators
The present invention is directed to novel compounds of Formula I. The compounds of the present invention are potent tyrosine kinase modulators, and are suitable for the treatment and prevention of diseases and conditions related to abnormal activities of tyrosine kinase receptors.
US08906943B2 Synthetic compounds and methods to decrease nicotine self-administration
Methods and small molecule compounds for smoking and CNS disease harm reduction are provided. One example of a class of compounds that may be used is represented by the compound having the structure IA or IB in the form of free base or a pharmaceutically acceptable salt, hydrate or solvate thereof.
US08906938B2 C5aR antagonists
Compounds are provided that are modulators of the C5a receptor. The compounds are substituted piperidines and are useful in pharmaceutical compositions, methods for the treatment of diseases and disorders involving the pathologic activation of C5a receptors.
US08906934B2 Pyridyl-and pyrimidinyl-substituted pyrrole-, thiophene-and furane-derivatives as kinase inhibitors
The present invention provides compounds of the formula (I), or the pharmaceutically acceptable salts thereof, wherein G, W, R2, R3, R4, R5 and R6 are as defined in the specification. Further objects of the invention are processes and intermediates for the preparation of the compounds of the formula (I), pharmaceutical compositions comprising them and methods for treating cell proliferative disorders. As a matter of fact, the compounds of the formula (I) are useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.
US08906930B2 Quinazoline derivatives
Novel quinazolinamide derivatives of the formula (I), in which R1-R4 and X have the meanings indicated in Claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 plays a role.
US08906929B2 Inhibitors of human immunodeficiency virus replication
The disclosure generally relates to compounds of formula I, including compositions and methods for treating human immunodeficiency virus (HIV) infection. The disclosure provides novel inhibitors of HIV, pharmaceutical compositions containing such compounds, and methods for using these compounds in the treatment of HIV infection.
US08906928B2 Substituted pyrazolo-pyrrolo-pyridine-dione compounds
The present invention relates to substituted pyrazolo-pyrrolo-pyridine-dione compounds and methods of synthesizing these compounds. The present invention also relates to pharmaceutical compositions containing substituted pyrazolo-pyrrolo-pyridine-dione compounds and methods of treating cell proliferative disorders, such as cancer, by administering these compounds or pharmaceutical compositions to subjects in need thereof.
US08906927B2 Penta-substituted tetrahydropyrimidines with aggregation-induced emission characteristics and preparation method and use thereof
The present invention provides a series of penta-substituted tetrahydropyrimidines with aggregation-induced emission (AIE) characteristics and preparation method and use thereof. The AIE penta-substituted tetrahydropyrimidines have structures shown as formula (I). R1 is selected from a group consisting of linear or branched alkyls and substituted alkyls. R2 and R4 is respectively selected from a group consisting of linear or branched alkyls, substituted alkyls, cycloalkyls, substituted cycloalkyls, aryls, substituted aryls, polycyclic aryls, substituted polycyclic aryls, heterocyclyls, substituted heterocyclyls, aromatic heterocyclyls and substituted aromatic heterocyclyls. R3 is selected from a group consisting of aryls, substituted aryls, polycyclic aryls, substituted polycyclic aryls, aromatic heterocyclyls and substituted aromatic heterocyclyls. The penta-substituted tetrahydropyrimidines can be prepared by multi-component reactions (MCR). There are 1˜3 aryls in the structure of the penta-substituted tetrahydropyrimidines. The penta-substituted tetrahydropyrimidines possess strong AIE properties and can be used for preparing organic electro-luminescence or photo-luminescence devices, or chemical and biological fluorescent sensors or probes.
US08906926B2 Substituted diketopiperazine analogs for use as drug delivery agents
Disclosed are drug delivery systems for the delivery of small molecule and macromolecular drugs. More particularly, disclosed are substituted analogs of 3,6-di(alkyl-4 aminobutyl)-2,5-diketopiperazine (which may also be referred to DKP), their use in the formulation of both small molecule and macromolecular drugs including therapeutic, prophylactic and diagnostic agents, stabilizing agents and systems for their delivery.
US08906920B2 N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-3-(7-tert-butylpyrazolo[1,5-A][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide, a dual modulator of chemokine receptor activity, crystalline forms and processes
The present invention provides a novel antagonist: N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-3-(7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide: or a pharmaceutically acceptable salt, solvate or prodrug, thereof, having unexpected dual CCR-2 and CCR-5 receptor activity. Crystalline forms, metabolites, pharmaceutical compositions containing the same and methods of using the same as agents for the treatment of inflammatory diseases, allergic, autoimmune, metabolic, cancer and/or cardiovascular diseases are also disclosed. The present disclosure also provides processes for preparing compounds of Formula (I) as provided herein, including N-((1R,2S,5R)-5-(tert-butylamino)-2-((S)-3-(7-tert-butylpyrazolo[1,5-a][1,3,5]triazin-4-ylamino)-2-oxopyrrolidin-1-yl)cyclohexyl)acetamide. Compounds that are useful intermediates of the process are also provided herein.
US08906913B2 Azabicyclohexanes
The present invention relates to novel compounds of Formula I, their pharmaceutically acceptable derivatives, tautomeric forms, stereoisomers including R and S isomers, polymorphs, prodrugs, metabolites, salts or solvates thereof. The invention also relates to processes for the synthesis of novel compounds of Formula I, their pharmaceutically acceptable derivatives, tautomeric forms, stereoisomers, polymorphs, prodrugs, metabolites, salts or solvates thereof.
US08906911B2 Chemokine receptor antagonists
Disclosed herein are chemokine receptor antagonists of formula (I) wherein R1, R2, and R3 are as defined in the specification. Compositions comprising such compounds; and methods for treating conditions and disorders using such compounds and compositions are also described.
US08906910B2 Imidazopyridine derivatives as PI3 kinase
This invention relates to the use of imidizopyridine derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide 3′ OH kinase family (hereinafter PI3 kinases), suitably, PI3Kα, PI3Kδ, PI3Kβ, and/or PI3Kγ. Suitably, the present invention relates to the use of imidizopyridines in the treatment of one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries. More suitably, the present invention relates to PI3Kβ selective imidizopyridine compounds for treating cancer.
US08906909B2 Phosphoinositide 3-kinase inhibitors with a zinc binding moiety
The instant application relates to deazapurines, thienopyrimidines and furopyrimidines with zinc-binding moiety based derivatives and their use in the treatment of phosphoinositide 3-kinase related diseases and disorders such as cancer. The instant application further relates to the treatment of histone deacetylase related disorders and diseases related to both histone deacetylase and phosphoinositide 3-kinase.
US08906906B2 Viral replication inhibitors
The present invention relates to a series of novel compounds having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to methods for the preparation of such compounds, as well as to novel intermediates useful in one or more steps of such syntheses. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. This invention further relates to the use of such compounds as medicines or in the manufacture of a medicament useful for the treatment of animals suffering from viral infections, in particular HIV infection. This invention further relates to methods for the treatment of viral infections in animals by the administration of a therapeutical amount of such compounds, optionally combined with one or more other drugs having antiviral activity.
US08906900B2 PRMT5 inhibitors and uses thereof
Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5-mediated disorders are also described.
US08906896B2 Platinum acridine anti-cancer compounds and methods thereof
Acridine containing cisplatin compounds are disclosed that show greater efficacy than other cisplatin compounds for treating cancer. The compounds are compounds of Formula I wherein the variables are defined herein.
US08906895B2 Optically active dibenzylamine derivative, and method for preparing thereof
Substantially optically pure (S)-trans-{4-[({2-[({1-[3,5-bis(trifluoromethyl)phenyl]ethyl}{5-[2-(methylsulfonyl)ethoxy]pyrimidin-2-yl}amino)methyl]-4-(trifluoromethyl)phenyl}(ethyl)amino)methyl]cyclohexyl}acetic acid, or a salt thereof, or a solvate thereof, which has actions of reducing amount of PCSK9 protein and increasing amount of LDL receptor.
US08906889B2 C-3 cycloalkenyl triterpenoids with HIV maturation inhibitory activity
Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-3 cycloalkenyl triterpenoids that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas I, II, III and IV: wherein X can be a C4-8 cycloalkyl, C4-8 cycloalkenyl, C4-9 spirocycloalkyl, C4-9 spirocycloalkenyl, C4-8 oxacycloalkyl, C4-8 dioxacycloalkyl, C6-8 oxacycloalkenyl, C6-8 dioxacycloalkenyl, C6-9 oxaspirocycloalkyl, or C6-9 oxaspirocycloalkenyl ring. These compounds are useful for the treatment of HIV and AIDS.
US08906888B2 Low-calcemic 16,23-diene 25-oxime analogs of 1α,25-dihydroxy vitamin D3
The present invention provides novel 16,23-diene 25-oxime ether analogs of 1,25-dihydroxy vitamin D3, compositions comprising these compounds and methods of using these compounds as inhibitors of CYP24. In particular, the novel compound of the invention are useful for treating diseases which benefit from a modulation of the levels of 1,25-dihydroxy vitamin D3, for example, cell-proliferative disorders.
US08906887B2 C7-fluoro substituted tetracycline compounds
The present invention is directed to a compound represented by Structural Formula (A): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula (A) are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula (A) and its therapeutic use.
US08906879B2 Combination for the treatment of cancer
The present invention relates to a method of treating cancer in a human and to pharmaceutical combinations useful in such treatment. In particular, the method relates to a cancer treatment method that includes administering 4-amino-1-(2-deoxy-2,2-difluoro-β-D-erythro-pentofuranosyl)pyrimidin-2(1H)-on 2′, 2′-difluoro-2′-deoxycytidine, or a pharmaceutically acceptable salt thereof, and N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)6,8-dimethy; -2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide, or a pharmaceutically acceptable salt or solvate thereof, to a human in need thereof.
US08906874B2 Bi-functional shRNA targeting Stathmin 1 and uses thereof
The present invention includes bifunctional shRNAs capable of reducing an expression of a Stathmin 1 gene; wherein at least one target site sequence of the bifunctional RNA molecule is located within the Stathmin 1 gene, wherein the bifunctional RNA molecule is capable of activating a cleavage-dependent and a cleavage-independent RNA-induced silencing complex for reducing the expression level of Stathmin 1.
US08906873B2 Modulation of huntingtin expression
Provided herein are methods, compounds, and compositions for reducing expression of huntingtin mRNA and protein in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate Huntington's disease, or a symptom thereof.
US08906871B2 MicromiRs
The present invention relates to very short heavily modified oligonucleotides which target and inhibit microRNAs in vivo, and their use in medicaments and pharmaceutical compositions.
US08906867B2 Production method of solid preparation and the solid preparations produced by the method
The production method prepares a solid preparation by dissolving water-insoluble and/or water indissolvable alkaline active pharmaceutical ingredient in an acidifier-containing acid solution to obtain medicated acid liquid; homogeneously mixing alkalizer, adjuvants and the medicated acid liquid, and carrying out wet granulation. The alkalizer is a reagent to reduce the acidity of the mixture of the alkalizer and the medicated acid liquid relative to the acidity of the medicated acid liquid. The preparation method avoids the problems in mechanical pulverization, such as environmental pollution, great loss and serious security risks. This method is simply operated, has high safety coefficient and is convenient for industrialized production. Also disclosed is the solid preparation produced by the method. The solid preparation produced by the method has better dissolution performance than that produced by prior art, and has better or at least equivalent stability and content uniformity with prior art.
US08906862B2 Multiple antigen delivery system using hepatitis E virus-like particle
This invention provides a peptide/nucleic acid composition for oral/mucosal, dual-modal activation of immune protection systems.
US08906861B2 Pharmaceutical compositions comprising cyclosporins
A composition is described herein comprising cyclosporin A, polysorbate 80, a polyoxyethylene stearate, and an oil; wherein the composition is an emulsion which is ophthalmically acceptable. Methods of treating diseases or conditions using said compositions, and medicaments related thereto, are also disclosed herein.
US08906855B2 Methods and compositions for treating conditions related to lack of blood supply, shock and neuronal injuries
A pharmaceutical composition comprising an amphiphilic emulsifier, a polar liquid carrier and, optionally, a lipid component. The amphiphilic emulsifier form free-moving, optionally lipid-carrying, micelles (LMs) in the polar liquid carrier. The pharmaceutical composition is free of hemoglobin and fluorocarbon and can be used for treating conditions related to lack of blood supply and to raise the blood pressure and correct hypovolemia.
US08906853B2 [N-Me-4-hydroxyleucine]-9-cyclosporin analogues for treatment and prevention of hepatitis C infection
The present invention relates to novel cyclosporine analogues having antiviral activity against HCV and useful in the treatment of HCV infections. More particularly, the invention relates to novel cyclosporine analogue compounds, compositions containing such compounds and methods for using the same, as well as processes for making such compounds.
US08906852B2 Inhibitors of protein tyrosine kinase activity
This invention relates to compounds that inhibit protein tyrosine kinase activity. In particular the invention relates to compounds that inhibit the protein tyrosine kinase activity of growth factor receptors, resulting in the inhibition of receptor signaling, for example, the inhibition of VEGF receptor signaling. The invention also provides compounds, compositions and methods for treating cell proliferative diseases and conditions and ophthalmic diseases, disorders and conditions.
US08906847B2 Prodrug comprising a drug linker conjugate
The present invention relates to a prodrug or a pharmaceutically acceptable salt thereof comprising a drug linker conjugate D-L, wherein -D is an amine containing biologically active moiety; and -L is a non-biologically active linker moiety -L1 represented by formula (I), wherein the dashed line indicates the attachment to the amine of the biologically active moiety and wherein R1, R1a, R2, R2a, R3, R3a, X, X1, X2, X3 have the meaning as indicated in the description and the claims and wherein L1 is substituted with one to four groups L2-Z and optionally further substituted, provided that the hydrogen marked with the asterisk in formula (I) is not replaced by a substituent; wherein L2 is a single chemical bond or a spacer; and Z is a carrier group. The invention also relates to A-L, wherein A is a leaving group, pharmaceutical composition comprising said prodrugs and their use as medicaments.
US08906846B2 Method of treating inflammatory bowel disease by administering a clip-inducing agent
The disclosure relates to methods for treating disorders of the mucosal tract such as the gastrointestinal system by targeting CLIP molecules. The methods are based on that CLIP in the groove of MHC class I or II molecules of the cells lining the mucosal surfaces of the body, such as the gastrointestinal tract, provides protection from MHC Class II or MHC class I mediated cell death, and therefore are useful for treating, inhibiting the development of a multitude of illnesses and conditions of the mucosal tract, including autoimmune disease.
US08906840B2 Low VOC composition to remove graffiti
A Low-VOC, water-based graffiti cleaner containing water, Glycol Ether EB, Acetone, DBE, Acetic acid, and a small amount of fragrance. The VOC content of this composition is less than or equal to 15.5%.
US08906837B2 Skin and hand cleaning means containing super-absorbing particles
The invention relates to compositions containing at least 10 wt.-% of water in relation to the total composition, if required, one or more additional solvents, optionally one or more emollients, if necessary, one of more emulsifiers, one or more surfactants which are different from the emulsifiers. The compositions being characterized such that they contain 0.01-30 wt.-% of super absorbing particles in relation to the total composition, and to the use thereof as skin and hand cleaning means.
US08906830B2 Capture agents and related compositions, methods and systems
The present disclosure relates to capture agents for the detection and/or separation of one or more targets in a sample. Described herein are multi-ligand capture agents comprising two or more ligands, and related compositions, methods and systems. In certain embodiments, the capture agents disclosed herein can be used for performing assays, including but not limited to assays for the detection and/or separation of targets.
US08906829B2 Synergistic algicidal compositions including hydrazone derivatives and copper
The present invention relates to the use of mixtures containing hydrazone compounds and copper for controlling the growth of algae.
US08906824B2 Water-absorbing polymer structures produced using polymer dispersions
The present invention relates to a process for the production of water-absorbing polymer structures, comprising the process steps of providing of an aqueous monomer solution comprising a polymerizable, monoethylenically unsaturated monomer (α1) carrying acid groups or a salt thereof; free-radical polymerization of the aqueous monomer solution to give a polymer gel, drying of the optionally comminuted polymer gel to give water-absorbing polymer structures, and surface post-crosslinking of the optionally ground and sieved water-absorbing polymer structures, wherein a thermoplastic polymer is added to the aqueous monomer solution before process step ii) or during process step ii), preferably before process step ii), or II) the polymer gel after process step ii) and before process step iv) or during process step iv), preferably before process step iv), or III) the water-absorbing polymer structure after process step iv).
US08906817B2 Sintered calcium sulfate ceramic material and sinterable calcium sulfate ceramic material
A sintered calcium sulfate ceramic material includes a plurality of major grains of calcium sulfate solid solutions, and a plurality of reaction grains located at boundaries of the major grains. Each of the reaction grains may be selected from the group consisting of calcium silicate and calcium phosphate. A. sinterable calcium sulfate ceramic material consisting of calcium sulfate and a sintering additive is also provided. The sintering additive comprises silica (SiO2).
US08906816B2 Laminate having improved wiping properties and a method for producing the laminate
A sheet of wiping material has a first outer surface and a second outer surface and a core region between the surfaces. The wiping material includes absorbent fibers and non-absorbent fibers. The wiping material has a stratified structure with a fiber gradient and a higher ratio of absorbent fibers to non-absorbent fibers at the outer surfaces of the wiping material than in the core region. A method of producing the wiping material is described.
US08906815B2 Composite nonwoven fibrous webs and methods of making and using the same
The disclosure relates to composite nonwoven fibrous webs including a population of sub-micrometer fibers having a median diameter less than one micrometer (μm), and a population of microfibers having a median diameter of at least 1 μm. At least, one of the fiber populations is oriented, and each composite nonwoven fibrous web has a thickness and exhibits a Solidity of less than 10%. The disclosure also relates to methods of making composite nonwoven fibrous webs, and articles including composite nonwoven fibrous webs made according to the methods. In exemplary applications, the articles may be used as gas filtration articles, liquid filtration articles, sound absorption articles, surface cleaning articles, cellular growth support articles, drug delivery articles, personal hygiene articles, or wound dressing articles.
US08906812B2 Wet etch and clean chemistries for MoOx
A method of removing non-noble metal oxides from material (e.g., semiconductor material) used to make a microelectronic device includes providing the material comprising traces of the conducting non-noble metal oxides; applying a chemical mixture (or chemical solution) to the material; removing the traces of the non-noble metal oxides from the material; and removing the chemical mixture from the material. The non-noble metal oxides comprise MoOx, wherein x is a positive number between 0 and 3. The chemical solution comprises any one of HNO3-based chemicals, H2SO4-based chemicals, HCl-based chemicals, or NH4OH-based chemicals.
US08906811B2 Shallow pn junction formed by in situ doping during selective growth of an embedded semiconductor alloy by a cyclic growth/etch deposition process
A silicon/carbon alloy may be formed in drain and source regions, wherein another portion may be provided as an in situ doped material with a reduced offset with respect to the gate electrode material. For this purpose, in one illustrative embodiment, a cyclic epitaxial growth process including a plurality of growth/etch cycles may be used at low temperatures in an ultra-high vacuum ambient, thereby obtaining a substantially bottom to top fill behavior.
US08906806B2 Method of manufacturing semiconductor device
A method of manufacturing a semiconductor device comprises forming a contact hole within an interlayer insulating film of a substrate and forming a contact plug while the substrate is heated. In forming the contact plug, the substrate is held on a stage within the chamber of a sputtering apparatus through a chuck, and an ESC voltage applied to the chuck is increased stepwise in a plurality of steps. First target power is applied to a target within the chamber to form a first Al film in the contact hole. Next, second target power higher than the first target power is applied to the target within the chamber to form a second Al film on the first Al film.
US08906801B2 Processes for forming integrated circuits and integrated circuits formed thereby
Processes for forming integrated circuits and integrated circuits formed thereby are provided in which a first dielectric layer including a first dielectric material is formed on an underlying substrate. A first etch mask having at least two patterned recesses is patterned over the first dielectric layer. At least one first-level via is etched in the first dielectric layer through one patterned recess in the first etch mask with a first etchant, and the first-level via is filled with electrically-conductive material. A second dielectric layer including a second dielectric material is formed over the first dielectric layer. A second etch mask having patterned recesses corresponding to the patterned recesses of the first etch mask is patterned over the second dielectric layer. Second-level vias are etched in the second dielectric layer through the patterned recesses in the second etch mask with a second etchant and exposed to the first etchant.
US08906796B2 Method of producing semiconductor transistor
A method of producing a semiconductor transistor involving formation of an ohmic electrode on an active layer composed of a GaN-based semiconductor includes a process of forming a first layer 11 composed of tantalum nitride on an active layer 3 and a second layer 12 composed of Al layered on the first layer 11 and a process of forming ohmic electrodes 9s and 9d in ohmic contact with the active layer 3 by heat treating the first layer 11 and the second layer 12 at a temperature of from 520° C. to 600° C.
US08906793B2 Borderless contact for an aluminum-containing gate
An aluminum-containing material is employed to form replacement gate electrodes. A contact-level dielectric material layer is formed above a planarization dielectric layer in which the replacement gate electrodes are embedded. At least one contact via cavity is formed through the contact-level dielectric layer. Any portion of the replacement gate electrodes that is physically exposed at a bottom of the at least one contact via cavity is vertically recessed. Physically exposed portions of the aluminum-containing material within the replacement gate electrodes are oxidized to form dielectric aluminum compound portions. Subsequently, each of the at least one active via cavity is further extended to an underlying active region, which can be a source region or a drain region. A contact via structure formed within each of the at least one active via cavity can be electrically isolated from the replacement gate electrodes by the dielectric aluminum compound portions.
US08906789B2 Asymmetric cyclic desposition etch epitaxy
The present disclosure relates to a method of forming an epitaxial layer through asymmetric cyclic deposition etch (CDE) epitaxy. An initial layer growth rate of one or more cycles of the CDE process are designed to enhance a crystalline quality of the epitaxial layer. A growth rate of the epitaxial material may be altered by adjusting a flow rate of one or more silicon-containing precursors within a processing chamber wherein the epitaxial growth takes place. An etch rate may also be altered by adjusting a temperature or partial pressure of one or more vapor etchants, or the temperature within the processing chamber. In some embodiments, an initial layer thickness that is greater than a critical thickness of the epitaxial material for strain relaxation is achieved with a low growth rate, followed by a high growth rate for the remainder of epitaxial growth. Other methods are also disclosed.
US08906785B2 Method of epitaxially growing silicon by atomic layer deposition for TFT flash memory cell
A method of growing an epitaxial silicon layer is provided. The method comprising providing a substrate including an oxygen-terminated silicon surface and forming a first hydrogen-terminated silicon surface on the oxygen-terminated silicon surface. Additionally, the method includes forming a second hydrogen-terminated silicon surface on the first hydrogen-terminated silicon surface through atomic-layer deposition (ALD) epitaxy from SiH4 thermal cracking radical assisted by Ar flow and flash lamp annealing continuously. The second hydrogen-terminated silicon surface is capable of being added one or more layer of silicon through ALD epitaxy from SiH4 thermal cracking radical assisted by Ar flow and flash lamp annealing continuously. In one embodiment, the method is applied for making devices with thin-film transistor (TFT) floating gate memory cell structures which is capable for three-dimensional integration.
US08906783B2 Method for cutting brittle sheet-shaped structure
A method for cutting brittle sheet-shaped structure is disclosed. A brittle sheet-shaped structure having a cutting surface including a first cutting line on the cutting surface of the brittle sheet-shaped structure is formed. The cutting surface is divided into a first section and a second section, wherein the first section has a predetermined shape. At least one second cutting line is formed on the second section along part of the first cutting line or a tangent line of the first cutting line. A number of third cutting lines are formed on the second section by taking the first cutting line as endpoints. A brittle sheet-shaped structure having the predetermined shape is finally obtained by splitting the brittle sheet-shaped structure along the first cutting line, the at least one second cutting line, and the third cutting lines.
US08906778B2 Method of semiconductor manufacturing process
The present invention related to a method for manufacturing a semiconductor, comprising steps of: providing a growing substrate; forming a semiconductor substrate on the growing substrate; forming a first structure with plural grooves and between the growing substrate and the semiconductor substrate; and changing the temperature of the growing substrate and the semiconductor substrate.
US08906770B2 Semiconductor structure that reduces the effects of gate cross diffusion and method of forming the structure
Gate cross diffusion in a semiconductor structure is substantially reduced or eliminated by forming multiple n-type gate regions with different dopant concentrations and multiple p-type gate regions with different dopant concentrations so that the n-type gate region with the lowest dopant concentration touches the p-type gate region with the lowest dopant concentration.
US08906768B2 Wrap around stressor formation
For the formation of a stressor on one or more of a source and drain defined on a fin of FINFET semiconductor structure, a method can be employed including performing selective epitaxial growth (SEG) on one or more of the source and drain defined on the fin, separating the fin from a bulk silicon substrate at one or more of the source and drain, and further performing SEG on one or more of the source and drain to form a wrap around epitaxial growth stressor that stresses a channel connecting the source and drain. The formed stressor can be formed so that the epitaxial growth material defining a wrap around configuration connects to the bulk substrate. The formed stressor can increase mobility in a channel connecting the defined source and drain.
US08906764B2 Non-volatile memory (NVM) and logic integration
A method of forming an NVM cell and a logic transistor uses a semiconductor substrate. A metal select gate of the NVM cell is formed over an NVM work function setting metal, the NVM work function setting metal is on a high-k dielectric, and a metal logic gate of a logic transistor is similarly formed over work function setting and high-k dielectric materials. The logic transistor is formed while portions of the metal select gate of the NVM cell are formed. The logic transistor is protected while the NVM cell is then formed including forming a charge storage region using nanocrystals and a metal control gate over a portion of the metal select gate and a portion of the charge storage region over the substrate. The charge storage region is etched to be aligned to the metal control gate.
US08906763B2 Method of manufacturing a dynamic random access memory (DRAM) including forming contact pads of adjacent cells by laterally etching a contact opening of a cell therebetween
A DRAM device includes a substrate including an active region having an island shape and a buried gate pattern. A mask pattern is over an upper surface portion of the substrate between portions of the buried gate pattern. A capping insulating layer fills a gap between portions of the mask pattern. A first pad contact penetrates the capping insulating layer and the mask pattern, and contacts a first portion of the substrate in the active region. Second pad contacts are under the capping insulating layer, and contact a second portion of the substrate in the active region positioned at both sides of the first pad contact. A spacer is between the first and second pad contacts to insulate the first and second pad contacts. A bit line configured to electrically connect with the first pad contact, and a capacitor configured to electrically connect with the second pad contacts, are provided.
US08906762B2 Flash memory with P-type floating gate
Methods for manufacturing non-volatile memory devices including peripheral transistors with reduced and less variable gate resistance are described. In some embodiments, a NAND-type flash memory may include floating-gate transistors and peripheral transistors (or non-floating-gate transistors). The peripheral transistors may include select gate transistors (e.g., drain-side select gates and/or source-side select gates) and/or logic transistors that reside outside of a memory array region. A floating-gate transistor may include a floating gate of a first conductivity type (e.g., n-type) and a control gate including a lower portion of a second conductivity type different from the first conductivity type (e.g., p-type). A peripheral transistor may include a gate including a first layer of the first conductivity type, a second layer of the second conductivity type, and a cutout region including one or more sidewall diffusion barriers that extends through the second layer and a portion of the first layer.
US08906761B2 Method of manufacturing for semiconductor device using expandable material
A semiconductor device is manufactured using an expandable material. The method includes forming a first gate insulating layer on a substrate, forming first and second gate structures on the first gate insulating layer, the first and second gate structures being spaced apart from each other at a distance, forming an expandable material on sidewalls and upper surfaces of the first and second gate structures, forming a gap-fill layer on the expandable material between the first and second gate structures, and performing a heat-treatment process to increase the volume of the expandable material.
US08906760B2 Aspect ratio dependent deposition to improve gate spacer profile, fin-loss and hardmask-loss for FinFET scheme
Techniques disclosed herein include systems and methods for an aspect ratio dependent deposition process that improves gate spacer profile, reduces fin loss, and also reduces hardmask loss in a FinFET or other transistor scheme. Techniques include depositing an aspect ratio dependent protective layer to help tune profile of a structure during fabrication. Plasma and process gas parameters are tuned such that more polymer can collect on surfaces of a structure that are visible to the plasma. For example, upper portions of structures can collect more polymer as compared to lower portions of structures. The variable thickness of the protection layer enables selective portions of spacer material to be removed while other portions are protected.
US08906751B2 Silicon controlled rectifiers (SCR), methods of manufacture and design structures
Silicon controlled rectifiers (SCR), methods of manufacture and design structures are disclosed herein. The method includes forming a common P-well on a buried insulator layer of a silicon on insulator (SOI) wafer. The method further includes forming a plurality of silicon controlled rectifiers (SCR) in the P-well such that N+ diffusion cathodes of each of the plurality of SCRs are coupled together by the common P-well.
US08906750B2 Method of encapsulation of a microcomponent
A method for encapsulating a microcomponent positioned on a substrate, including: a) production of an electrical contact pad on the substrate; b) production of a portion of sacrificial material covering the microcomponent and the electrical contact pad; c) production of an encapsulation layer covering the sacrificial material and a first face of the substrate; d) production, through the substrate, of a hole aligned with the electrical contact pad and emerging at the portion of sacrificial material; e) elimination of the portion of sacrificial material through the hole; f) production, in the hole, of a conductive portion electrically connected to the electrical contact pad, forming a conductive via.
US08906745B1 Method using fluid pressure to remove back metal from semiconductor wafer scribe streets
A method of dividing a semiconductor wafer in which a sheet of deformable material engaging the metal layer side of the wafer has pressurized fluid applied thereto to cause the metal layer to break at the locations of wafer scribe streets.
US08906741B2 Electronic package structure having side-wing parts outside of a package layer for dissipating heat and method for making the same
A method for making an electronic package structure is provided which comprises: providing a substrate; providing an inductor module; assembling the inductor module and the substrate so that they define a space; injecting package glue into the space defined by the inductor module and the substrate so as to form a package layer.
US08906735B2 Donor substrates, methods of manufacturing donor substrates, organic light emitting display devices and methods of manufacturing organic light emitting display devices
A donor substrate includes a base layer, a light to heat conversion layer on the base layer, an interlayer on the light to heat conversion layer, a low molecular weight transfer layer on the interlayer and an organic transfer layer on the low molecular weight transfer layer. The low molecular weight transfer layer includes an element in Group I or a compound of elements in Group I and Group VII.
US08906725B2 Crystallization processing for semiconductor applications
A method and apparatus for forming a crystalline semiconductor layer on a substrate are provided. A semiconductor layer is formed by vapor deposition. A pulsed laser melt/recrystallization process is performed to convert the semiconductor layer to a crystalline layer. Laser, or other electromagnetic radiation, pulses are formed into a pulse train and uniformly distributed over a treatment zone, and successive neighboring treatment zones are exposed to the pulse train to progressively convert the deposited material to crystalline material.
US08906717B2 Organic light emitting diode display device having built-in touch panel and method of manufacturing the same
An organic light emitting diode (OLED) display device having a built-in touch panel and a manufacturing method thereof in which an OLED array and a touch array are formed on a flexible substrate and thus the OLED display device has flexibility, and a flexible printed circuit board for driving the touch array is integrally formed with a printed circuit board for driving the OLED array and thus manufacturing costs are reduced are disclosed. The OLED display device includes an OLED array formed on a lower flexible substrate, a touch array formed on an upper flexible substrate, and an adhesive layer adhering the upper flexible substrate to the lower flexible substrate such that the touch array and the OLED array face each other.
US08906713B2 LED lamp using blue and cyan LEDs and a phosphor
Many thousands of micro-LEDs (e.g., 25 microns per side) are deposited on a substrate. Some of the LEDs are formed to emit a peak wavelength of 450 nm (blue), and some are formed to emit a peak wavelength of 490 nm (cyan). A YAG (yellow) phosphor is then deposited on the LEDs, or a remote YAG layer is used. YAG phosphor is most efficiently excited at 450 nm and has a very weak emission at 490 nm. The two types of LEDs are GaN based and can be driven at the same current. The ratio of the two types of LEDs is controlled to achieve the desired overall color emission of the LED lamp. The blue LEDs optimally excite the YAG phosphor to produce white light having blue and yellow components, and the cyan LEDs broaden the emission spectrum to increase the CRI of the lamp while improving luminous efficiency. Other embodiments are described.
US08906712B2 Light emitting diode and method of fabrication thereof
A method includes providing an LED element including a substrate and a gallium nitride (GaN) layer disposed on the substrate. The GaN layer is treated. The treatment includes performing an ion implantation process on the GaN layer. The ion implantation process may provide a roughened surface region of the GaN layer. In an embodiment, the ion implantation process is performed at a temperature of less than approximately 25 degrees Celsius. In a further embodiment, the substrate is at a temperature less than approximately zero degrees Celsius during the ion implantation process.
US08906709B1 Combinatorially variable etching of stacks including two dissimilar materials for etch pit density inspection
Provided are methods of high productivity combinatorial (HPC) inspection of semiconductor substrates. A substrate includes two layers of dissimilar materials interfacing each other, such as a stack of a silicon bottom layer and an indium gallium arsenide top layer. The dissimilar materials have one or more of thermal, structural, and lattice mismatches. As a part of the inspection, the top layer is etched in a combinatorial manner. Specifically, the top layer is divided into multiple different site-isolated regions. One such region may be etched using different process conditions from another region. Specifically, etching temperature, etching duration and/or etchant composition may vary among the site-isolated regions. After combinatorial etching, each region is inspected to determine its etch-pit density (EPD) value. These values may be then analyzed to determine an overall EPD value for the substrate, which may involve discarding EPD values for over-etched and under-etched regions.
US08906706B2 Method of fabricating a mask structure for patterning a workpiece by ions
A method of fabricating workpieces includes one or more layers on a substrate that are masked with an ion implantation mask comprising two or more layers. The mask layers include a first mask layer closer to the substrate, and a second mask layer on the first mask layer. The method also comprises ion implanting one or more of the layers on the substrate. Ion implantation may form portions with altered physical properties from the layers under the mask. The portions may form a plurality of non-magnetic regions corresponding to apertures in the mask.
US08906705B2 Semiconductor device with pads of enhanced moisture blocking ability
A semiconductor device is provided having a pad with an improved moisture blocking ability. The semiconductor device has: a circuit portion including a plurality of semiconductor elements formed on a semiconductor substrate; lamination of insulator covering the circuit portion, including a passivation film as an uppermost layer having openings; ferro-electric capacitors formed in the lamination of insulator; wiring structure formed in the lamination of insulator and connected to the semiconductor elements and the ferro-electric capacitors; pad electrodes connected to the wiring structure, formed in the lamination of insulator and exposed in the openings of the passivation film; a conductive pad protection film, including a Pd film, covering each pad electrode via the opening of the passivation film, and extending on the passivation film; and stud bump or bonding wire connected to the pad electrode via the conductive pad protection film.
US08906698B2 Method and apparatus for measuring fluorescence in liquids
A method of measuring the fluorescence of a fluorescent marker compound dissolved or dispersed in a bulk material includes: (a) measuring a characteristic of the fluorescence of a mixture of said bulk material and said fluorescent marker compound; (b) quenching the fluorescence of the fluorescent marker compound to produce a quenched mixture; (c) measuring the characteristic of the fluorescence of the quenched mixture; (d) comparing the fluorescent characteristic of the mixture with the fluorescent characteristic of the quenched mixture; and (e) correcting the measured fluorescent emission characteristic for the effects of the absorbance of the bulk material. The measurement may be further corrected to account for the absorbance of the material which is also known to have an effect on the measured fluorescence. A method of tagging and identifying a bulk material with a fluorescent marker compound, and an apparatus for carrying out the methods are also described.
US08906696B2 Deformable polymer testing device
A testing device uses a selectively deformable substrate to capture and retain spherical beads for genetic experimentation. A method of fabricating the device is described in which a silicon substrate can be coated with a photosensitive, bio-compatible polymer for photolithographic patterning using a single mask exposure. The polymer is patterned with a matrix of wells, each well capable of expansion to accept placement of a bead in the well, and contraction to secure the bead in the well. The polymer can exhibit piezoelectric properties that cause it to respond mechanically to a selected electrical excitation.
US08906694B2 Organometallic fluorescent sensors for nitric oxide detection and imaging
Disclosed herein are methods of detecting the presence and/or concentration of nitric oxide using organometallic complexes and changes in fluorescence.
US08906693B2 Materials and methods for measuring nitric oxide levels in biological fluids
The subject invention presides novel devices and methods for the measurement of nitric oxide in biological samples, including wound fluid samples. These advantageous devices and methods can be used for clinicians to monitor the wound's nitric oxide metabolism and/or response to treatment.
US08906690B2 Methods for simultaneous estimation of quantitative minerology, kerogen content and maturity in gas shale and oil-bearing shale
A method for estimating characteristics of a formation including collecting a formation sample, preparing the sample, and analyzing the sample using FTIR comprising identifying the kerogen lineshape and intensity. The method includes using the lineshape to obtain kerogen maturity, using the maturity to obtain the kerogen spectrum, and using the kerogen spectrum to obtain the mineralogy and kerogen content.
US08906685B2 Hanging drop devices, systems and/or methods
The present disclosure relates general to devices, systems, and methods of using such devices in creating and handling hanging drops of fluid. The present disclosure also relates to cell culture devices, methods and/or systems of using such devices as well as the use of cell culture devices, for example, for research and high throughput screening.
US08906684B2 Three dimensional cell patterned biopolymer scaffolds and methods of making the same
Provided are methods of the production of patterned 3-dimensional biopolymer scaffolds containing living cells. The methods include selective photopolymerization of biopolymers to create patterned structures and the patterning of cells within relatively homogenous slabs of biopolymer using dielectrophoresis. Also provided are patterned 3-dimensional biopolymer scaffolds generated by the methods and their use.
US08906683B2 Methods and materials for increasing potency of cells
Disclosed herein are methods and materials for producing a more developmentally potent cell from a less developmentally potent cell. Specifically exemplified herein are methods that comprise introducing an expressible dedifferentiating polynucleotide sequence into a less developmentally potent cell, wherein the transfected less developmentally potent cell becomes a more developmentally potent cell capable of differentiating to a less developmentally potent cell of its lineage of origin or a different lineage.
US08906677B2 Generation and maintenance of stem cells
The present invention provides for the generation and maintenance of pluripotent cells by culturing the cells in the presence of an ALK5 inhibitor.
US08906676B2 Modified human four helical bundle polypeptides and their uses
Modified human four helical bundle (4HB) polypeptides and uses thereof are provided.
US08906674B2 Sample preparation apparatus and cell analyzer
A sample preparation apparatus comprising: a storage chamber that can store therein a liquid sample including an analysis target to be analyzed; a concentrated sample storage chamber that is provided to communicate with the storage chamber and that stores therein concentrated liquid having an analysis target having a higher concentration than that of the liquid sample; and an analysis target transportation section for transporting the analysis target included in the liquid sample stored in the storage chamber to the concentrated sample storage chamber. A cell analyzer is also disclosed.
US08906670B2 Zero-mode waveguides with non-reflecting walls
The application relates to improved optical containment structures, methods of manufacture and use, and systems for employing same. The optical containment structures generally comprise zero-mode waveguide structures having non-reflective walls. The non-reflective walls allow the preparation of optical containment regions in which the optical containment dimensions can be decoupled from the solution containment dimensions. The application also relates to methods for producing islands of functionality within nanoscale apertures.
US08906668B2 Synergistic bacterial compositions and methods of production and use thereof
Provided are therapeutic compositions containing Ecobiotic™ populations for prevention, treatment and reduction of symptoms associated with a dysbiosis of a mammalian subject such as a human.
US08906667B2 Increasing NADPH-dependent products
A method of increasing cellular NADPH levels by expressing one or more genes that encode an enzyme that causes the production of NADPH. The system is combined with other enzymes that require NADPH, thus improving the overall yield of the desired product.
US08906666B2 Engineering resistance to aliphatic alcohols
The present disclosure provides improved systems for the biological production of aliphatic alcohol compounds. In particular, the present disclosure provides biological systems that show improved resistance to aliphatic alcohol toxicity; in some embodiments, such improved resistance allows for increased levels of aliphatic alcohol production. In one aspect, the present disclosure provides engineered microorganisms that both produce an aliphatic alcohol compound and show resistance to that compound as measured by an ability to grow to predetermined levels in the presence of a given concentration of the compound.
US08906665B2 Methods and compositions for the recombinant biosynthesis of fatty acids and esters
The present disclosure identifies methods and compositions for modifying photoautotrophic organisms, such that the organisms efficiently convert carbon dioxide and light into compounds such as esters and fatty acids. In certain embodiments, the compounds produced are secreted into the medium used to culture the organisms.
US08906663B2 Nitrilases
The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
US08906659B2 Plasma treatment for growth factor release from cells and tissues
Aspects of the present invention are related to methods comprising contacting an endothelial cell in an endothelial cell population with a non-thermal plasma to release an angiogenic growth factor. The released angiogenic growth factor may induce endothelial cell proliferation. In certain embodiments, the angiogenic growth factor is fibroblast growth factor-2. Preferably, the non-thermal plasma may be an atmospheric pressure dielectric barrier discharge. Additional aspects of the present invention are directed to methods for treating a disease comprising promoting angiogenesis by contacting an endothelial cell in a endothelial cell population with a non-thermal plasma to release an angiogenic growth factor. The angiogenic growth factor may induce endothelial cell proliferation. Further aspects of the present invention are directed to methods for treating a disease comprising inhibiting angiogenesis by contacting an endothelial cell in a endothelial cell population with a non-thermal plasma to reduce the number of endothelial cells in the population.
US08906658B2 Compositions and methods for producing isoprene free of C5 hydrocarbons under decoupling conditions and/or safe operating ranges
The invention features methods for producing isoprene from cultured cells wherein the cells in the stationary phase. The invention also provides compositions that include these cultured cells and/or increased amount of isoprene. The invention also provides for systems that include a non-flammable concentration of isoprene in the gas phase. Additionally, the invention provides isoprene compositions, such as compositions with increased amount of isoprene or increased purity.
US08906657B2 Processes for producing fermentable sugars and energy-dense biomass for combustion
This invention provides processes to convert biomass into energy-dense biomass for combustion, alone or in combination with another solid fuel. Some embodiments provide processes for producing fermentable sugars and energy-dense biomass from cellulosic biomass, comprising extracting the feedstock with steam and/or hot water to produce an extract liquor containing hemicellulosic oligomers, dissolved lignin, and cellulose-rich solids; separating the extract liquor, to produce dewatered cellulose-rich solids; hydrolyzing the dewatered cellulose-rich solids, thereby removing a portion of the cellulose, to produce intermediate solids (with higher energy density) and a hydrolysate; drying the intermediate solids to produce energy-dense biomass; and recovering fermentable sugars from the hydrolysate. The energy-dense biomass may be pelletized into biomass pellets, which may have a similar energy density as torrefied pellets from wood. The hemicellulosic oligomers may be further hydrolyzed to produce additional fermentable sugars. The fermentable sugars may be fermented to ethanol or another product.
US08906654B2 Kluyveromyces marxianus strains and method of using strains
Described are novel Kluyveromyces marxianus strains NRRL Y-50798 and Y-50799, that were obtained by UV-C irradiation of wild-type K. marxianus NRRL Y-1109 cultures. The UV-C-mutagenized strains were incubated under anaerobic conditions on xylose or glucose medium for a period of 5 months at 46° C. before being selected. These mutagenized strains have potential application in large-scale industrial conversion of lignocellulosic sugars to fuel ethanol given their ability to ferment at temperatures at 46° C. and above.
US08906652B2 Thermal cycler for PCR including temperature control bladder
Methods and devices for performing chemical reactions under controlled temperature are described. In one embodiment, the devices provided by the invention comprise a housing dimensioned to hold a reaction chamber disposed within an interior volume of the housing. The reaction chamber has thermally conductive interior and exterior surfaces defining an internal volume therein at a first temperature. The device also includes at least one temperature-control substance at a second temperature received into said bladder and expels said temperature-control substance, the bladder expands to about substantially at least a portion of said exterior surfaces of said reaction chamber to enable thermal exchange between said temperature-control substance and the said internal volume of reaction chamber.
US08906651B2 Compositions comprising fibrous polypeptides and polysaccharides
Isolated polypeptides are disclosed comprising an amino acid sequence encoding a monomer of a fibrous polypeptide attached to a heterologous polysaccharide binding domain. Composites comprising same, methods of generating same and uses thereof are all disclosed.
US08906648B2 Recombinant production of vascular endothelial growth factor
A process for recovering and purifying refolded heparin binding proteins produced in heterologous host cells includes the step of incubation of the solubilized protein with a polyanionic species such as dextran sulfate.
US08906640B2 Methods of measuring protein and/or fat digestibility and uses thereof
The present invention provides methods for continuous measurement of protein and/or triglyceride digestibility during a meal. Stable isotope of 15N-spirulina protein and 2H5-phenylalanine was added to the nutritional supplement. Protein digestibility is calculated by measuring the ratio [15N]PHE to [2H5]PHE in plasma and the nutrition. In another embodiment, [1,1,1-13C3]tripalmitin and [2,2-2H2]palmitic acid were added to the meal. The ratio between [1-13C]palmitic acid/[2,2-2H2]palmitic acid will represent the percentage digestion of triglycerides by lipase from the pancreas.
US08906639B2 Method of determining factor XIII with the aid of plasma-based reference material
The present invention is in the field of in-vitro diagnostics and relates to a method of determining the blood-clotting factor XIII (factor XIII, F XIII) with the aid of plasma-based reference material, and a test kit for carrying out the method.
US08906638B2 Method for quantification of remnant-like lipoprotein cholesterol and kit for same
A method for quantifying remnant-like lipoprotein cholesterol in a sample simply and accurately without requiring separation operations, and a kit therefor are disclosed. A method for quantifying cholesterol in a remnant-like lipoprotein in a sample containing different lipoproteins including the remnant-like lipoprotein comprises a step (1) of erasing cholesterol in lipoproteins other than the remnant-like lipoprotein; and a step (2) of quantifying cholesterol in the remaining remnant-like lipoprotein. The step (1) is carried out under an action of a cholesterol esterase having a molecular weight of more than 40 kDa and not having a subunit having a molecular weight of not more than 40 kDa; and the step (2) is carried out under an action of a cholesterol esterase having a molecular weight of not more than 40 kDa or a cholesterol esterase having a subunit having a molecular weight of not more than 40 kDa.
US08906637B2 Methods for detecting targets
The present invention provides method and compositions for detecting target molecules present on cells and tissues. In particular, the methods involve adding primary antibodies such as scFv-targeted lactamase that are directed against a target of interest (e.g., cancer markers) to a tissue sample, followed by adding a lactam-containing compound and finally a lactamase reporter system. In some preferred embodiments, the lactamase reporters are fluorescent reporters that bind to the test tissue. In some particularly preferred embodiments, the test tissue contains at least once cancer cell and/or at least one cancer-associated marker.
US08906634B2 Monitoring and inhibiting human immunodeficiency virus infection by modulating HMGB1 dependent triggering of HIV-1 replication and persistence
Compositions and methods for modulating human immunodeficiency virus (HIV) infection involving substances that inhibit the ability of high mobility box 1 (HMGB1) protein to interact with natural killer (NK) cells. Therapeutic compositions comprising antibodies and drugs, such as glycyrrhizin, which bind to HMGB1. Methods of detecting or monitoring HIV infection involving detection or quantitation of HMGB1 or antibodies specific for HMGB1 in a biological sample.
US08906633B2 Detection of synthetic cannabinoids
The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens enable said methods and kits.
US08906630B2 Assays for detecting pathogenic respiratory bacteria
The present invention encompasses methods, assays and kits for the detection of pathogenic bacteria in a patient and for the differential diagnosis of pulmonary diseases associated with pathogenic bacteria from pulmonary diseases not associated with pathogenic bacteria.
US08906628B2 Nucleic acid amplification methods for specific detection of E. coli O157:H7 without co-detection of E. coli O55:H7
Disclosed are methods and kits for the specific detection of E. coli O157:H7 and not E. coli O55:H7 from samples such as: complex food matrices, water, beverages, fermentation broths, forensic & biological samples, and environmental samples including food processing and manufacturing surfaces. In some embodiments, a method of the disclosure comprises: hybridizing at least a first pair of polynucleotide primers to at least a first target polynucleotide sequence, hybridizing at least a second pair of polynucleotide primers to at least a second target polynucleotide sequence, amplifying the at least first and at least second target polynucleotide sequences, and detecting the first and second amplified target polynucleotide sequence products, wherein the detection of both the first amplified target polynucleotide sequence product and the second amplified target polynucleotide sequence product is indicative of the presence of E. coli O157:H7 in a sample and not E. coli O55:H7.
US08906622B2 Method of amplification
The present invention relates generally to a method of amplifying a nucleic acid region of interest and, more particularly, to a method of amplifying a nucleic acid region of interest via a nested single tube PCR. The method is designed to provide a means to selectively inactivate the functionality of the outer primer or primers and to maintain amplification efficiency throughout the reaction. The development of a means to achieve efficient amplification by the outer primer followed by efficient amplification with the inner primers, in the context of a single tube nested PCR, is useful in a range of applications including, but not limited to, the diagnosis and/or monitoring of disease conditions which are characterized by specific gene sequences and the characterization or analysis of specific gene regions of interest. Still further, the method enables quantification to be performed and not just simple detection.
US08906621B2 Cross priming amplification of target nucleic acids
The present invention relates to methods of amplification of nucleic acid sequences; more particularly, it relates to methods of amplifying target sequences by utilizing cross priming isothermal amplification. The present invention relates to methods of marking the amplification target sequence during the amplification reaction and rapid detection of the target sequence. The present invention also relates to reagent kits for rapid nucleic acid diagnosis and the nucleic acid detection of pathogenic microorganisms such as bacteria, viruses, as well as to diagnoses related to human genetic diseases.
US08906618B2 Apparatus and methods for parallel processing of micro-volume liquid reactions
Disclosed herein are apparatuses and methods for conducting multiple simultaneous micro-volume chemical and biochemical reactions in an array format. In one embodiment, the format comprises an array of microholes in a substrate. Besides serving as an ordered array of sample chambers allowing the performance of multiple parallel reactions, the arrays can be used for reagent storage and transfer, library display, reagent synthesis, assembly of multiple identical reactions, dilution and desalting. Use of the arrays facilitates optical analysis of reactions, and allows optical analysis to be conducted in real time. Included within the invention are kits comprising a microhole apparatus and a reaction component of the method(s) to be carried out in the apparatus.
US08906608B2 Methods for reducing the range in concentrations of analyte species in a sample
The present invention relates to the fields of molecular biology, combinatorial chemistry and biochemistry. Particularly, the present invention describes methods and kits for dynamically reducing the variance between analyte taken from complex mixtures.
US08906607B2 Method for modulating double-strand break-induced homologous recombination
The present invention concerns a method for modulating double-strand break-induced homologous recombination through the identification of effectors that modulate said double-strand break-induced homologous recombination by uses of interfering agents; these agents are capable of modulating double-strand break-induced homologous recombination through their respective actions on said effectors. The present invention also concerns the uses of these effectors and interfering agents and derivatives, respectively, by introducing them in an eukaryotic cell in order to modulate and more particularly to increase double-strand break-induced homologous recombination and gene targeting efficiency. The present invention also relates to specific derivatives of identified effectors and interfering agents, vectors encoding them, compositions and kits comprising such derivatives in order to modulate and more particularly to increase double-strand break-induced homologous recombination and gene targeting efficiency.
US08906601B2 Methods for stabilizing a bioprosthetic tissue by chemical modification of antigenic carbohydrates
Methods are provided herein for modifying antigenic carbohydrate epitopes within a xenographic bioprosthetic tissue by oxidation of vicinal diols to form aldehydes or acids and subsequence reductive amination of aldehydes to form stable secondary amines, or amidation or esterification of acids to form stable amides or esters. Advantageously, methods provided herein mitigate the antigenicity of the bioprosthetic tissue while leaving the overall tissue structure substantially undisturbed, and thereby enhance the durability, safety and performance of the bioprosthetic implant.
US08906595B2 Method for improving resist pattern peeling
A method of fabricating a mask is described. The method includes receiving receiving an integrated circuit (IC) design layout that has a first pattern layer including a first feature and has a second pattern layer including a second feature, wherein the first pattern layer and the second pattern layer are spatially related when formed in a substrate such that the first and second features are spaced a first distance between a first edge of the first feature and a second edge of the second feature, modifying the IC design layout by adjusting a dimension of the first feature based on the first distance, and generating a tape-out data from the modified IC design layout for mask making. The method further includes applying a logic operation (LOP) to the IC design layout.
US08906594B2 Negative-working thick film photoresist
Disclosed are compositions for negative-working thick film photophotoresists based on acrylic co-polymers. Also included are methods of using the compositions.
US08906592B2 Antireflective coating composition and process thereof
The invention relates to an antireflective coating composition comprising a crosslinkable polymer, where the crosslinkable polymer comprises at least one unit of fused aromatic moiety, at least one unit with a phenylene moiety in the backbone of the polymer, and at least one hydroxybiphenyl unit, furthermore where the polymer comprises a crosslinking moiety of structure (4), where R′3, R″3 and R′″3 are independently hydrogen or a C1-C4alkyl. The invention further relates to a process for forming an image using the composition.
US08906590B2 Antireflective coating composition and process thereof
The invention relates to an antireflective coating composition comprising a crosslinker and a crosslinkable polymer capable of being crosslinked by the crosslinker, where the crosslinkable polymer comprises a unit represented by structure (1): -A-B-C-  (1) where A is a fused aromatic ring, B has a structure (2), and C is a hydroxybiphenyl of structure (3) where R1 is C1-C4alkyl and R2 is C1-C4alkyl. The invention further relates to a process for forming an image using the composition.
US08906584B2 Photomask and method for forming pattern of semiconductor device using the same
A semiconductor device includes a cell mask pattern disposed in a cell region of a mask substrate and a vernier mask pattern disposed in a vernier region of the mask substrate. The vernier mask pattern includes a variable mask pattern portion to transfer a different shape of pattern depending on the magnitude of exposure energy.
US08906580B2 De-alloyed membrane electrode assemblies in fuel cells
Embodiments disclosed herein present a method for membrane electrode assembly (MEA) fabrication in fuel cells utilizing de-alloyed nanoparticle membranes as electrodes. A method for fabrication of a fuel cell electrode assembly, comprising: preparing a catalyst coated membrane, forming a membrane electrode assembly, assembling a fuel cell, and de-alloying the membrane electrode assembly. Further disclosed is a fuel cell apparatus, comprising a de-alloyed catalyst and a cathode comprising, a first membrane electrode assembly, wherein the de-alloyed catalyst is coated on the membrane electrode assembly.
US08906572B2 Polymer-electrolyte membrane, electrochemical fuel cell, and related method
A polymer-electrolyte membrane is presented. The polymer-electrolyte membrane comprises an acid-functional polymer, and an additive incorporated in at least a portion of the membrane. The additive comprises a fluorinated cycloaliphatic additive, a hydrophobic cycloaliphatic additive, or combinations thereof, wherein the additive has a boiling point greater than about 120° C. An electrochemical fuel cell including the polymer-electrolyte membrane, and a related method, are also presented.
US08906570B2 System and method for observing anode fluid composition during fuel cell start-up
A fuel cell system including a fuel cell stack having a plurality of fuel cells, the fuel cell stack including an anode supply manifold and an anode exhaust manifold, a first valve in fluid communication with at least one of the anode supply manifold and the anode exhaust manifold, wherein the first valve includes an inlet for receiving a fluid flow and an outlet for exhausting a fluid, a sensor for measuring at least a fluid pressure at the inlet and the outlet of the first valve, wherein the sensor generates a sensor signal representing the pressure measurement, and a processor for receiving the sensor signal, analyzing the sensor signal, and determining a composition of a fluid in the fuel cell system based upon the analysis of the sensor signal.
US08906568B2 Monitoring the operational state of a fuel cell stack
A technique is described herein for monitoring the operational state of a fuel cell stack by the detection of nonlinearity in such a manner that an external test signal for frequency response is generated and applied to the fuel cell stack during operation, the resulting signal output from the fuel cell stack is measured, and the harmonic content of the measured signal is analyzed, the method including: applying a multiple frequency test signal comprising at least two sinusoidal waves as the test signal for frequency response to the fuel cell stack; and analyzing the resulting current or voltage signal output from the fuel cell stack.
US08906567B2 Fuel cell system
The present invention detects a failure in an FC converter. A target voltage determination section determines an output target voltage for a fuel cell. A superimposition signal generation section generates a predetermined reference signal to be superimposed onto the output target voltage. A voltage command signal generation section generates a voltage command signal by superimposing the reference signal onto the output target voltage. A frequency characteristics calculation section calculates the frequency characteristics of the reference signal component superimposed on the output voltage of the fuel cell. A failure judgment section judges that a failure occurs in the FC converter if a value of the calculated frequency characteristics is less than the lower limit threshold value of an allowable range established based on reference characteristics. A gain adjustment section adjusts the gains in the FC converter so that the frequency characteristics calculated by the frequency characteristics calculation section correspond to the reference characteristics.
US08906566B2 Fuel cell stack shutdown operation controlling anode pressure using discharge fuel consumption estimate
A method including shutting down an electrochemical fuel cell stack wherein anode pressure is controlled according to a stack discharge fuel consumption estimate.
US08906561B2 Bio-fuel cell
A bio-fuel cell includes at least one bio-fuel cell element. The bio-fuel cell element includes an anode, a cathode, an anode container filled with the bio-fuel, a proton exchange membrane sandwiched between the anode and the cathode, and a guide plate. The cathode includes a catalyst layer. The catalyst layer includes a number of tube carriers having electron conductibility, a number of catalyst particles uniformly adsorbed on inner wall of each of the tube carriers, and proton conductor filled in each of the tube carriers. The tube carriers cooperatively define a number of reaction gas passages. One end of each of the tube carriers connects with the proton exchange membrane. The guide plate is disposed on a surface of the cathode away from the proton exchange membrane.
US08906559B2 Electrolyte including an additive for rechargeable lithium battery and rechargeable lithium battery including same
An electrolyte for a rechargeable lithium battery includes a non-aqueous organic solvent; a lithium salt; and an additive including vinylene carbonate, fluoroethylene carbonate, and a nitrile-based compound represented by Formula 1: wherein n ranges from 1 to 12 and R1 and R2 are independently a halogen, a hydrogen, or an alkyl group. Further, the alkyl group can be CmH(2m+1), in which m ranges from 1 to 10. The electrolyte for a rechargeable lithium battery improves storage stability of the rechargeable lithium battery at a high temperature. And, a rechargeable lithium battery including the electrolyte has improved storage stability.
US08906548B2 Actinic and electron beam radiation curable electrode binders and electrodes incorporating same
A process for manufacturing an electrode utilizing electron beam (EB) or actinic radiation to cure electrode binding polymers is provided. A process is also disclosed for mixing specific actinic or EB radiation curable chemical precursors with electrode solid particles, application of the mixture to an electrode current collector, followed by the application of actinic or EB radiation to the current collector for curing the polymer, thereby binding the electrode material to the current collector. Lithium ion batteries, electric double layer capacitors, and components produced therefrom are also provided.
US08906547B2 Negative electrode material for non-aqueous electrolyte secondary battery and non-aqueous electrolyte secondary battery
The present invention provides a negative electrode material for a non-aqueous electrolyte secondary battery that includes particles of a silicon-based active material, the particles of a silicon-based active material being coated with a film of an organosilicon compound that contains a perfluoropolyether group, and a non-aqueous electrolyte secondary battery therewith. As a result, there is provided a negative electrode material for a non-aqueous electrolyte secondary battery that is high in capacity, excellent in initial charge/discharge efficiency and cycle characteristics and high in safety and reliability, and a non-aqueous electrolyte secondary battery that uses the negative electrode material.
US08906546B2 Non-aqueous electrolyte and lithium air battery including the same
A non-aqueous electrolyte and a lithium air battery including the same. The non-aqueous electrolyte may include an oxygen anion capturing compound to effectively dissociate the reduction reaction product of oxygen formed during discharging of the lithium air battery, reduce the overvoltage of the oxygen evolution reaction occurring during battery charging, and enhance the energy efficiency and capacity of the battery.
US08906543B2 Battery having tab with insulator for electrode assembly
A battery including an electrode assembly having a positive electrode, a negative electrode and a separator interposed between the electrodes, a container housing the electrode assembly, a tab attached to a first side of an uncoated region of the electrode assembly, the tab having a terminal, a first insulator interposed between the tab and a first inner surface of the container, and a cap assembly closing the container and having the terminal passing therethrough.
US08906542B2 Sodium chalcogenide electrodes for sodium batteries
A sodium-ion electrochemical cell described herein comprises a cathode, an anode, and a non-aqueous sodium-containing electrolyte therebetween. The electrolyte comprises a sodium salt dissolved in a liquid organic carrier. The cathode comprises at least one transition metal chalcogenide compound in an initial discharged or partially discharged state and having the formula NaxMX2Cln, wherein 0
US08906541B2 Battery module with integrated thermal management system
A controller identifies a condition of a hazardous internal short by comparing patterns of series element voltages to the last known balance condition of the series elements. If the loaded or resting voltage of one or more contiguous series elements uniformly drop from the previously known condition by an amount consistent with an over-current condition, an over-current internal short circuit fault is registered. The desired response is to prevent the affected series elements from heating to a hazardous temperature by summoning the maximum heat rejection capability of the system until the short ceases and the affected elements cool, the cooling function is no longer able to operate due to low voltage, or the affected series string has drained all of its energy through the short. Also includes are responses that allow the battery pack to continue to power the cooling system even though it may enter an over-discharged state.
US08906538B2 Separator for non-aqueous secondary battery, process for producing the same, and non-aqueous secondary battery
A first object of the present invention is to provide a separator including a polyethylene microporous membrane and a heat-resistant porous layer, and that has a sufficient shutdown function and a sufficient heat resistance, and can be formed with a reduced thickness and can overcome the problem of slidability. A first aspect of the present invention is a separator for a non-aqueous secondary battery. The separator includes a microporous membrane of primarily polyethylene, and a heat-resistant porous layer of a primarily heat-resistant polymer formed on at least one surface of the microporous membrane. (1) The microporous membrane has a Gurley number of 25 to 35 sec/100 cc·μm per unit thickness. (2) The heat-resistant porous layer contains inorganic fine particles having an average particle diameter of 0.1 to 1.0 μm. (3) The inorganic fine particles are 40% to 80% in volume with respect to a total volume of the heat-resistant polymer and the inorganic fine particles. (4) The heat-resistant porous layer has a total thickness of 3 to 12 μm.
US08906534B2 Stacked multi-cell battery concept
A device is provided that includes a battery layer on a substrate, where a first battery cell is formed in the battery layer. The first battery cell includes a first anode, a first cathode, and a first electrolyte arranged between the first anode and the first cathode, where the first anode, the first cathode, and the first electrolyte are arranged in the battery layer such that perpendicular projections onto the substrate of each of the first anode and the first cathode are non-overlapping. A method of manufacturing such device is also provided. A system is also provide that includes such device for supplying power to an electronic device.
US08906532B2 Electrochemical cells with improved heat collection and transfer systems
Provided herein are electrochemical cells having improved heat collection and transfer systems. For example, one electrochemical cell includes a drawn can having a blind side and a second side opposite the blind side. The cell also includes a positive terminal disposed in the blind side of the can and electrically coupled to at least one positive electrode disposed within the can and a negative terminal disposed in the blind side of the can and electrically coupled to at least one negative electrode disposed within the can. The cell further includes a base coupled to a substantially flat edge disposed on the second side of the can. A bottom surface of the base is adapted to maintain a substantially flat configuration when coupled to a heat sink.
US08906528B2 Bicycle electric power source assembly
A bicycle electric power source assembly comprises a tubular member, an electric power source member and a restricting member. The tubular member includes an inner peripheral surface, an outer peripheral surface and a through hole that passes through the tubular member between the inner peripheral surface and the outer peripheral surface. The electric power source member is disposed inside the tubular member. The electric power source member includes a restriction accepting part. The restricting member is disposed in the through hole. The restricting member includes a restricting part that engages with the restriction accepting part to restrict relative movement of the electric power source member with respect to the tubular member in an axial direction of the tabular member.
US08906527B2 Multi-layer composite getter
A multi-layer composite getter is described. Also described is a method for the manufacturing of the multi-layer composite getter and electrochemical devices for energy storage that employ the multi-layer composite getter.
US08906523B2 Energy device with integral collector surface for electromagnetic energy harvesting and method thereof
An apparatus, method, and system to harvest and store electromagnetic energy is disclosed. The present invention uses, for example, conductive surfaces within the energy storage component itself as a means of electromagnetic energy collection. The surface may be an integral portion of the energy device, such as a charge collection surface within a battery or a capacitor that mainly provides the battery or a capacitor with a necessary function. In another embodiment of the invention a metallic or conductive surface is added to and specifically built into the energy device during manufacturing for the main purpose of collecting electromagnetic energy for the energy device but is otherwise not necessary for the energy storage component. Once the energy is collected, it can be rectified either via rectification components that were built directly into the energy storage component during its manufacture or connected external to the energy storage component but within the energy device. The so-designed energy device may represent a self-sustaining, autonomous electromagnetic energy harvesting—energy storage device.
US08906522B2 Hard non-oxide or oxide ceramic / hard non-oxide or oxide ceramic composite hybrid article
Described are hybrid articles comprising at least one hard non-oxide or oxide ceramic component of at least 95% of theoretical density directly bonded to, and different from, a hard non-oxide or oxide ceramic composite component comprising a tribology enhancing component. The at least one hard non-oxide or oxide ceramic component comprises a member of the group consisting of silicon carbide, pressureless sintered silicon carbide, liquid phase sintered silicon carbide, reaction bonded silicon carbide, tungsten carbide, aluminum oxide, and silicon nitride. The at least one hard non-oxide or oxide ceramic composite component comprises a member of the group consisting of silicon carbide, pressureless sintered silicon carbide, liquid phase sintered silicon carbide, reaction bonded silicon carbide, tungsten carbide, aluminum oxide, and silicon nitride.
US08906518B2 Triazole derivative, light-emitting element, light-emitting device, and electronic device
A substance having high excitation energy is provided. In particular, a substance having high triplet excitation energy is provided. Further, a light-emitting element, a light-emitting device, and an electronic device each having high emission efficiency and low driving voltage are provided. A triazole derivative to which an amino group is bonded is provided. In addition, a light-emitting element, a light-emitting device, and an electronic device each including the triazole derivative to which the amino group is bonded are provided.
US08906516B2 Galvannealed steel sheet having high corrosion resistance after painting
A galvannealed steel sheet having high corrosion resistance after painting includes, on a mass percent basis, C: 0.05% to 0.15%, Si: 0.1% to 1.0%, Mn: 0.5% to 2.7%, Al: ≦1.00%, P: ≦0.025%, S: ≦0.025%, and Cr: 0% to 0.8% as chemical components, the remainder being Fe and incidental impurities. The galvannealed steel sheet includes a galvannealed layer in an amount of 20 to 120 g/m2 per side, a percentage of exposed zinc metal of the galvannealed layer surface being 20% or more and less than 80%, and an amount of internal oxidation in a region disposed not more than 5 μm from the surface of the steel sheet is 0.02 g/m2 or more and 0.1 g/m2 or less: Si≦0.68%, Cr≦−1.25Si+0.85, and Si>0.68%, Cr=0, wherein Si and Cr denote respective contents (mass %) of Si and Cr.
US08906509B2 Process for the production of a dark-color multi-layer coating
A process for the production of a dark-color multi-layer coating, comprising the successive steps: (1) applying an NIR-opaque coating layer A′ from a pigmented, solvent- or waterborne coating composition A to a substrate, (2) applying a coating layer B′ from a pigmented coating composition B onto the substrate provided with coating layer A′, wherein the pigment content of coating composition A consists 90 to 100 wt. % of at least one aluminum flake pigment and 0 to 10 wt. % of at least one further pigment, which is selected in such a way that NIR-opaque coating layer A′ exhibits low NIR absorption, wherein the pigment content of coating composition A comprises <90 wt. % of 10 to 80 nm thick aluminum flake pigments, wherein the pigment content of coating composition B consists 50 to 100 wt. % of at least one black pigment with low NIR absorption and 0 to 50 wt. % of at least one further pigment, which is selected in such a way that coating layer B′ exhibits low NIR absorption and that the dark-color multi-layer coating exhibits a brightness L* (according to CIEL*a*b*, DIN 6174), measured at an illumination angle of 45 degrees to the perpendicular and an observation angle of 45 degrees to the specular, of at most 10 units, wherein the sum of the respective wt. % equals 100 wt. %, and wherein the coating layers A′ and B′ are cured.
US08906508B2 Method of toughening thermoplastic polyurethane and articles comprising toughened thermoplastic polyurethane
A method of toughening thermoplastic polyurethane (TPU). The TPU is dipped into a urethane solution having a penetrating agent, then heated and dried for a period sufficient to toughen the surface. Also, articles such as golf balls having a toughened thermoplastic polyurethane surface. The toughened thermoplastic polyurethane surface is more scuff-resistant and has a greater strain-rate shear resistance than the TPU.
US08906507B2 Coating system for achieving excellent MVSS adhesion
A coating system includes a clear coat layer and a sealant. The clear coat layer is formed from a clear coat composition that comprises a crosslinkable carbamate-functional resin and an aminoplast. Optionally, the coating system further includes a sub-clear coat layer. The sealant is bonded to the clear coat layer opposite the sub-clear coat layer. Optionally, the coating system further includes a tie coat layer and that is disposed between the sealant and the clear coat layer. An adhesion promoter is present in the clear coat composition in an amount of less than or equal to about 3% by weight based on the total weight of resin solids of the clear coat composition. Further, the adhesion promoter is present in at least one of the sub-clear coat composition and the tie coat composition in an amount sufficient to increase adhesion between the clear coat layer and the sealant.
US08906505B2 Composition for colloidal crystal comprising core-shell particles and styrene polymer
A composition for colloidal crystals including core-shell particles and a monomer having a particular structure. The core-shell particles constitute 25% to 65% by weight of the composition, and the monomer constitutes 35% to 75% by weight of the composition. The core has an average particle size from 50 to 900 nm. Each particle includes a core and a shell. The shell is formed of a linear polymer composed of at least one of styrene and a monomer having a particular structure. One end of the linear polymer is covalently bonded to the core. The refractive index of the core (n(core)) satisfies the following formulae: wherein R1 denotes a hydrogen atom or a methyl group, and y is 0 or 1, n(shell)−n(core)≧0.07, n(shell) denoting the refractive index of the shell, and n(B)−n(core)≧0.07, n(B) denoting the refractive index of the monomer (B1) after curing.
US08906502B2 Organic powder useful as the replacement of mineral filler in composites
This invention is about organic powder materials useful as the replacement of mineral or inorganic fillers in composites. The organic powder materials have particle size less than 60 μm and are visually non-differentiable in composites. The gel coat materials with the organic powder have uniform color appearance and have improved color stability when exposed to moisture.
US08906493B2 Structural composite panel for an aircraft including a protection against high energy impacts
A structural panel consisting of a stratified composite material includes one face exposed to impacts and further includes a layer consisting of a hyper-elastic material bonded adhesively to its other face. According to this embodiment, debris striking the exposed face of this composite panel will have some of its energy dissipated by the local rupture of the composite skin, while the rest of the energy is absorbed by the deformation of the layer of hyper-elastic material that captures the debris and expels it again.
US08906488B2 Biodegradable blends and films having nano-structural features
A thermoplastic polymer composition with a tertiary blend of a carbon dioxide-derived polymer, a thermoplastic cellulose derivative, and a thermoplastic compatibilizer is described. The composition can be melt-processed into flexible, thin films that have fine nano-scale structural features in both the cross-directional and machine-directional orientations, for use in various products. The films, which are made from relatively brittle materials, exhibit a greater degree of ductility, elongation capacity, and strength than the primary, original component materials as binary-blends from which the film is made.
US08906486B2 Flexible sheet materials for tensioned structures, a method of making such materials, and tensioned false ceilings comprising such materials
A flexible sheet material of thickness less than half a millimeter for making tensioned structures such as false ceilings, in particular, the material including microprojections formed by displacing the material from which it is made, said material presenting an acoustic absorption coefficient which is higher than that of the same material without said projections.
US08906485B2 High strength ultra-high molecular weight polyethylene tape articles
Processes for the production of high strength polyethylene tape articles from high strength ultra-high molecular weight multi-filament yarns, and to the tape articles, fabrics, laminates and impact resistant materials made therefrom.
US08906479B2 Compositions of polyamide and ionomer
Disclosed is a shaped article comprising a composition comprising polyamide and ionomer wherein the ionomer comprises a mixture of Zn and alkali metal (M2) cations wherein the Zn/M2 equivalent ratio is from about 0.6 to about 6. The articles prepared from the compositions with mixed ion ionomers exhibit high stiffness, hardness and toughness, good scratch resistance, desirable low melt viscosity and high processability.
US08906476B2 Composition and recording sheet with improved optical properties
A composition is provided, which comprises a water-soluble salt of a divalent metal; a complexing agent having an affinity for the divalent metal; and an optical brightening agent. Methods of using the composition, and recording sheets which include the composition, are also disclosed.
US08906470B2 Method for producing a microfabricated atomic vapor cell
The present invention relates to a method for producing a microfabricated atomic vapor cell, including a step of forming at least one cavity in a substrate and closing the cavity at one side. The method further includes: —a step of depositing a solution including an alkali metal azide dissolved in at least one of its solvents, —a step of evaporating such solvent for forming a recrystallized alkali metal azide, —a step of decomposing the recrystallized alkali metal azide in an alkali metal and nitrogen, such alkali metal depositing in the cavity of the substrate.
US08906469B2 Coating method using plasma shock wave and method for manufacturing coated substance
Disclosed is a coating method using a plasma shock wave, the method including the steps of: irradiating a pulse laser to a first surface of a mixed layer obtained by mixing powders and resin to generate a plasma, the mixed layer being formed on a second surface of a substance to be coated; striking the powders on the second surface by using a shock wave of the plasma; and forming a coat of the powders on the second surface.
US08906466B2 Esterified lignocellulosic materials and methods for making them
Methods of making esterified lignocellulosic materials and resulting compositions and articles are disclosed.
US08906465B2 Method for forming multilayer coating film
This invention provides a method for forming multilayer coating film excelling in smoothness and distinctness of image, by 3-coat-1-bake system in which a step of applying onto a coating object a water-based intermediate paint (X) to form an intermediate coating film; a step of adjusting the solid content of the intermediate coating film to 70-100 mass %; a step of applying onto the intermediate coating film a water-based base coating paint (Y) containing 30-55 mass parts of alcoholic solvent having a boiling point of 170-250° C., to form a base coating film; a step of adjusting the solid content of the base coating film to 70-100 mass %; a step of applying a clear paint (Z) comprising 40-60 mass parts of carboxyl-containing compound and 60-40 mass parts of polyepoxide onto the base coating film to form a clear coating film; and heating the intermediate coating film, base coating film and clear coating film at 100-120° C. for 3-10 minutes and thereafter further heating them at 130-160° C. for 10-30 minutes; are successively carried out.
US08906460B2 Composition for use as NOx removing translucent coating
An improved composition capable of forming a translucent coating on a construction material surface comprising at least: a) photocatalytic titanium dioxide particles having at least a de-NOx activity; b) a silicon based-material in which said particles are dispersed, wherein said silicon based material includes at least one polysiloxane; and c) particles having a de-HNO3 activity selected from calcium carbonate, magnesium carbonate and mixtures thereof.
US08906457B2 Method of atomic layer deposition using metal precursors
Methods for deposition of metal films consisting essentially of Co, Mn, Ru or a lanthanide on surfaces using metal coordination complexes are provided. The precursors used in the process include a 2-methylimine pyrrolyl ligand and/or N,N′-diisopropylformamidinato ligand. The precursors may also contain cyclopentadienyl, pentamethylcyclopentadienyl or pyrrolyl groups.
US08906447B2 Method of producing hybrid nano-filament electrodes for lithium metal or lithium ion batteries
Disclosed is a method of producing a hybrid nano-filament composition for use in a lithium battery electrode. The method comprises: (a) providing an aggregate of nanometer-scaled, electrically conductive filaments that are substantially interconnected, intersected, physically contacted, or chemically bonded to form a porous network of electrically conductive filaments, wherein the filaments comprise electro-spun nano-fibers that have a diameter less than 500 nm (preferably less than 100 nm); and (b) depositing micron- or nanometer-scaled coating onto a surface of the electro-spun nano-fibers, wherein the coating comprises an electro-active material capable of absorbing and desorbing lithium ions and the coating has a thickness less than 10 μm (preferably less than 1 μm). The same method can be followed to produce an anode or a cathode. The battery featuring an anode or cathode made with this method exhibits an exceptionally high specific capacity, an excellent reversible capacity, and a long cycle life.
US08906446B2 Apparatus and method for electroless deposition of materials on semiconductor substrates
An apparatus is provided having a closable chamber that can be sealed and is capable of withstanding an increased pressure and high temperature. The chamber has several inlet ports for the supply of various process liquids, such as deposition solutions, DI water for rinsing, etc., and a port for the supply of a gas under pressure. The apparatus also includes a solution heater and a control system for controlling temperature and pressure in the chamber. Uniform deposition is achieved by carrying out the deposition process under pressure and under temperature slightly below the boiling point of the solution. The solution can be supplied from above via a shower head formed in the cover, or through the bottom of the chamber. Rinsing or other auxiliary solutions are supplied via a radially moveable chemical dispensing arm that can be arranged above the substrate parallel thereto.
US08906443B2 Frozen aerated confections
A frozen aerated confection having an overrun of at least 40% and a fat component in an amount of 2 to 20% (by weight of the frozen aerated confection), said fat component comprising triglycerides of fatty acids wherein no more than 55% (by weight of the fatty acids) of the fatty acids in the triglycerides are saturated, less than 8% (by weight of the triglycerides) of the triglycerides are long chain SSS triglycerides; characterized in that the ratio of the percentage of fat that is solid at 5° C. to the percentage of the fatty acids in the triglycerides that are saturated (by weight of the fatty acids) is greater than 1 and in that the fat component comprises at most 60% (by weight) cocoa butter or shea nut oil.
US08906441B2 Peanut spread
Nut spreads having a stabilizer which is a blend of certain palm oil fraction stabilizers with certain cocoa butters and/or cocoa butter equivalents and/or replacers and/or substitutes and/or extenders (with similar fatty acid profile to cocoa butter). When these fats are used in combination, particularly at ratios preferred herein, they impart a smooth creamy texture to the final nut butter or nut butter based products and more importantly provide enhanced stability during storage, preventing oil separation in the final product during prolonged storage. The texture and spreadability of the final nut spread based product achieved by using this blend is also superior to the texture and spreadability obtained by using conventional palm oil alone. Preferably the cocoa butters, equivalents, replacers and substitutes are not hydrogenated.
US08906437B2 Edible container for foodstuffs and process for producing the same
An open-ended edible container for foodstuffs is provided. The open-ended container is composed of cereals and/or fruits in a sheet formed of a binder wherein the inner surface of the container is very lightly patterned while the outer surface has a smooth texture with embedded flakes. A process for manufacturing edible containers for foodstuffs is also provided and includes the steps of: pouring a liquid batter on baking plates, partially cooking the batter for providing a sheet, depositing cereals and/or fruit flakes as a layer onto the sheet, cooking the sheet, and giving the desired shape to the container. The inner surface of the container is very lightly patterned while the outer surface of the container has a rough texture with embedded flakes.
US08906436B2 Single serve beverage additive cartridge
Beverage additive cartridges, beverage brewing systems and methods of brewing a beverage whereby a beverage additive cartridge containing an ingredient is used in combination with a beverage brewing cartridge to add the ingredient of the additive cartridge to the brewed fluid flow of the brewing cartridge. The resultant brew is an ingredient-brewed fluid mixture that outflows a brewing machine via an outlet probe.
US08906434B2 Compositions and methods for reducing stool volume and stool odor
The present invention provides animal food compositions comprising high quality proteins and highly digestible carbohydrates which result in reduced stool production and stool odor upon ingestion by an animal, and methods for use.
US08906428B2 Mineral composition, and preparation method thereof
The mineral composition is prepared by mixing 100 parts by weight of deep sea water, dead sea water, underground salt water, sea water, aboveground salt water, mineral water, drinking water, fresh water, underground water or water with salt dissolved therein, 1-15 parts by weight of sea weed, 0.1-10 parts of weight of a vegetable oil, 0.1-10 parts by weight of an animal oil, 0.1-10 parts by weight of a soap or saponificated product of a vegetable oil, 0.1-10 parts by weight of a soap or saponificated product of an animal oil, 0.1-5 parts by weight of glycerin, 0.1-5 parts by weight of an alcohol, 0.1-5 parts by weight of baking powder, and 0.1-10 parts by weight of one or more acids of glacial acetic acid, phytic acid, malic acid, erythorbic acid, tartaric acid, citric acid, succinic acid and L-aspartic acid.
US08906426B2 Water-free, emulsifier-free, and preservative-free vehicle for active ingredients
A vehicle for carrying active ingredients, wherein the vehicle is water-free, emulsifier-free, and preservative free. Preferably, the vehicle is used to carry a skin care formulation for treating skin conditions that provides noticeable results within two weeks or less.
US08906419B2 Pharmaceutical composition containing water soluble drug
The present invention is directed to a process of preparing beads coated with a water soluble drug for incorporation into a pharmaceutical composition comprising: (a) preparing a supersaturated drug solution containing a desired amount of drug, which is completely saturated at a first temperature but which is supersaturated at a second temperature which is below the first temperature; and (b) coating inert beads with the drug solution, said drug solution being maintained at or below the first temperature but above the second temperature, and said beads maintained at a second temperature, wherein the second temperature is less than the first temperature and wherein the solution containing the drug is supersaturated at the second temperature, as well as to the pharmaceutical compositions containing same.
US08906415B1 Calcium phosphate nanowhisker particles, method of making and using the same
Calcium phosphate nanowhisker particles, methods of making and method of using are described.
US08906414B1 Methods and compositions for improving bioavailability of epigallocatechin gallate (EGCG)
Compositions and methods of increasing the bioavailability of catechins are presented. Compositions for increasing the bioavailability of catechins include compositions where the catechin is added to a solution of ethanol and water; compositions where the catechin is encapsulated within a nanoparticle; and compositions in which a nanoparticle complex is formed between the catechin and the nanoparticle. Each of these compositions was shown to increase bioavailability of EGCG and is useful in treating diseases such as Alzheimer's and HIV-associated dementia.
US08906411B2 Pre-compacted calcium-containing compositions
A pre-compacted materiel comprising one or more calcium-containing compounds and one or more sugar alcohols, wherein the calcium-containing compound having a polycrystallic porous structure. The pre-compacted material is preferably obtained by roller compaction and is suitable for use in the further processing of the pre-compacted material into composition like e.g. tablets.
US08906409B2 Acoustically sensitive drug delivery particles comprising non-lamellar forming phosphatidylcholine
Novel acoustically sensitive drug carrying particles comprising non-lamellar forming lipids are disclosed, as well as uses and methods thereof. The drug carrying particles accumulate in the diseased target tissue and efficiently release their payload upon exposure to acoustic energy.
US08906407B2 Protected active compound formulations of amino acids and process for their preparation
Active compound formulations for animal nutrition of amino acids, vitamins, enzymes and pigments, which are suitable for providing the active compounds in protected form for the nutrition of stock animals, in particular ruminants, and a process for the preparation of these protected active compound formulations.
US08906405B2 Isotopically modified compounds and their use as food supplements
A nutrient composition comprises an essential nutrient in which at least one exchangeable H atom is 2H and/or at least one C atom is 13C. The nutrient is thus protected from, inter alia, reactive oxygen species.
US08906401B2 Antimicrobial medical devices containing chlorhexidine free base and salt
The present disclosure invention relates to medical devices treated with a solution comprising one or more solvents and a combination of chlorhexidine free base and a water-soluble chlorhexidine salt in a weight/weight ratio of between about 1:1 to about 1:5, preferably about 1:1.
US08906393B2 Biofilm inhibiting composition
Polysaccharide-containing extracts isolated from a host cell containing nucleotide sequences encoding genes pamA, pamB and pamC, wherein the extract is capable of inhibiting biofilm formation produced by gram-negative bacteria, gram-positive bacteria and fungi, and methods to inhibit biofilm formation or remove biofilms that have already formed.
US08906392B2 Nanocluster compositions and methods
Compositions, methods of making, and methods of using nanoclusters in which the nanoclusters comprise a plurality of nanoparticles having a core of nanoparticles arranged such that the surfaces of the nanoparticles contact adjacent nanoparticles, the nanoparticles comprise an active ingredient, and the nanocluster has a mass median aerodynamic diameter of from about 0.25 μm to about 20 μm.
US08906391B2 Thermorod for active drug release and method for manufacturing the same
Disclosed is a thermorod capable of actively releasing drugs according to temperature of the thermorod and a method of manufacturing the same. The thermorod generates heat by eddy current loss and hysteresis loss in an induced magnetic field. The thermorods can effectively administer drugs, such as anti-cancer drugs, since the thermorods may be used to perform local hyperthermia at 36.5° C. or above and to actively control the active drug release and delivery according to temperature as well. The thermorods may be useful in the treatment of resting tumor cells along with hyperthermia by performing a surgical operation on lesion sites of biological tissues. Using the thermorod, the drug is effectively delivered to an affected part in response to the active drug release. This can minimize the toxicity caused by an increase in blood drug concentration, which occurs when a drug is administered by a conventional method.
US08906390B2 Synthetic lipid rafts and methods of use
Compositions and methods for delivering cargo to cells are provided. One aspect provides a synthetic vesicle containing caveolin 1 or a fragment thereof in an amount effective to form lipid rafts in the vesicle. The synthetic vesicles can be used to deliver polynucleotides, proteins, therapeutic agents, or a combination thereof to specific membrane-bound compartments of a cell. In certain aspects, the synthetic vesicles can deliver cargo to cellular organelles such as mitochondria.
US08906389B2 Determination of the efficacy of an anti-mycobacterial vaccination
The invention relates to methods and reagents for determining efficacy of vaccine, particularly of a tuberculosis vaccine.
US08906385B2 Interferon-inducing porcine reproductive and respiratory syndrome virus isolate
Provided are polynucleotides and proteins encoded by them which are useful for stimulating an immune response against Porcine reproductive and respiratory syndrome virus (PRRSV) in swine. The compositions can contain a newly discovered PRRSV strain or recombinant versions of it or polynucleotides isolated or derived from it, which can be provided as pharmaceutical preparations.
US08906384B2 Antiviral activity of bovine type III interferon against foot-and-mouth disease virus
A member of the bovine type III IFN family, boIFN-λ3, was identified and characterized. We expressed boIFN-λ3 using a recombinant replication defective human adenovirus type 5 (Ad5) and demonstrated antiviral activity against foot-and-mouth disease virus (FMDV) and vesicular stomatitis virus (VSV) in bovine cells in vitro. Cattle were inoculated with Ad5-boIFN-λ3 followed by intradermolingual or aerosol FMDV challenge. Results demonstrated that the type III IFN family is conserved in bovines and that treatment of cattle with boIFN-λ3 alone or in combination with IFN-α is able to confer delayed and reduced severity of FMD. Furthermore inoculation with Ad5-boIFN-λ3 alone conferred full protection against aerosol challenge for at least 7 days after administration suggesting that type III IFN used in combination with FMD vaccines could fill one of the current gaps in emergency vaccination against FMDV.
US08906380B2 Fungal immunostimulatory compositions
Methods are disclosed which are useful in increasing maturation of dendritic cells from CD14+ mononuclear cells, by contact with a composition comprising a fucose-containing glycoprotein fraction from Ganoderma lucidum. The extract can also be used for increasing production of a cytokine or a chemokine in a dendritic cell or CD19+ B cell. In addition, a fucose-containing glycoprotein fraction from Ganoderma lucidum can be administered to a subject identified as needing increased immunoglobulin, cytokine, or chemokine production.
US08906373B2 Use of TNF-alpha inhibitor for treatment of psoriasis
The invention describes methods of treating erosive polyarthritis comprising administering a TNFα antibody, or antigen-binding portion thereof. The invention also describes a method for testing the efficacy of a TNFα antibody, or antigen-binding portion thereof, for the treatment of erosive polyarthritis.
US08906372B2 Purified antibody composition
The invention provides a method for producing a host cell protein-(HCP) reduced antibody preparation from a mixture comprising an antibody and at least one HCP, comprising an ion exchange separation step wherein the mixture is subjected to a first ion exchange material, such that the HCP-reduced antibody preparation is obtained.
US08906371B2 Human anti-IFN-γ neutralizing antibodies as selective IFN-γ pathway inhibitors
This invention provides antibodies that interact with or bind to human interferon-gamma (IFN-γ) and methods for treating IFN-γ mediated diseases by administering a pharmaceutically effective amount of antibodies to IFN-γ. Methods of detecting the amount of IFN-γ in a sample using antibodies to IFN-γ are also provided.
US08906364B2 Antimicrobial compositions and uses thereof
The present invention provides compositions for preventing growth and proliferation of biofilm embedded microorganisms on devices comprising: (a) a cationic polypeptide and (b) a bis-guanide or a salt thereof. The invention further provides methods for preparing medical devices with such compositions.
US08906363B2 Fusion proteins for the treatment of CNS
This disclosure relates to compositions capable of use in the treatment of spinal cord injuries and related disorders of the central nervous system (CNS), and in particular, compositions including proteoglycan degrading molecules and compositions capable of blocking and/or over coming the activity of neuronal growth inhibitory molecules, as well as fusion proteins which includes a proteoglycan degrading domain and a domain capable of blocking and or over coming the activity of neuronal growth inhibitory molecules.
US08906358B2 Leishmania challenge model
The present invention provides a method for effectively and reproducibly infecting canines with Leishmania infantum using sand flies to vector the parasite. The inventive method comprises several steps, including ensuring canines are naïve to Leishmania, infecting the canines using bites of Leishmania-infected sand fly bites, and evaluating successful transmission of the Leishmania parasites.
US08906356B2 Mutant interleukin-2 (IL-2) polypeptides
The present invention relates to mutant IL-2 polypeptides that act as receptor antagonists. The mutant IL-2 polypeptides bind CD 25 but do not activate the IL-2 receptor. Also provided are methods of using the mutant IL-2 polypeptides, for example, to treat a patient who has cancer or a viral infection. The mutant polypeptides can also be used in various delivery systems.
US08906351B2 2,2′-furoin derivatives and use thereof to light skin
The invention relates to the use of compounds of the formula (I), in which R1, R2, m and n have the meanings indicated in the Claims, and/or physiologically acceptable salts, tautomers, stereoisomers and/or solvates thereof, including mixtures thereof in all ratios, for the inhibition of tyrosinase and for lightening the skin. The invention also relates to the use of the compounds of the formula (I) in the prophylaxis, therapy or progress control of pigment disorders of the skin. The invention furthermore relates to preparations comprising the compounds of the formula (I) in combination with at least one further active compound and to a process for the preparation of the preparations by mixing the compounds of the formula (I) with a vehicle which is physiologically acceptable for topical applications.
US08906350B2 Tooth whitening accelerator formulation and method of using the same
In an embodiment, a tooth whitening accelerator composition includes a salt of boric acid dissolved in a polyol carrier. The tooth whitening accelerator composition can be used in a method of whitening teeth that includes applying the tooth whitening accelerator to teeth and applying a tooth whitening formulation to the teeth.
US08906349B2 Oral care composition
Disclosed are oral care compositions and the use of such oral care compositions for treating conditions caused by biofilm formation. Also disclosed are methods for inhibiting biofilm formation and/or degrading biofilm. The oral care composition includes a sesquiterpenoid and an antimicrobial agent, in which the sesquiterpenoid and the antimicrobial agent are present in an amount effective to inhibit and/or degrade a biofilm in the oral cavity.
US08906348B2 Oral care compositions
Oral care compositions that are stable, pourable and swishable suspension containing suspending polymer(s). Optional further components include abrasives, surfactants, flavorings, colorings, anti-plaque agents, anti-tartar agents, agents for sensitive teeth, fluoride ion sources and sweeteners.
US08906347B2 Oral stannous compositions
The present invention relates to an aqueous oral composition comprising: a) from 0.2% to 3% divalent metal ions comprising: i. from 0.1% to 1.5% of zinc ions; ii. from 0.1% to 2% of tin (II) ions; and b) a source of fluoride ions; c) a silica dental abrasive; d) one or more chelants having a MW of less than 1000 and capable of forming water-soluble complexes with the zinc ions, wherein the chelants comprise less than 0.2% linear polyphosphates having a chain length of four or more; e) an orally acceptable carrier comprising at least 20% total water; wherein the pH of the composition is from 5 to 6.5, the molar ratio of the chelants to the divalent metal ions is at least 0.70:1 and at least 80% by weight of the total zinc ions are solubilised within the composition. The composition of the invention has been found to give improved antimicrobial activity from the zinc/stannous combination without significant taste, staining or stability problems, compared to compositions having lower levels of chelants.
US08906346B2 MRI contrast agent for lymphography based on iron oxide nanoparticles and method for imaging lymph node using the same
Provided are a contrast agent for contrast imaging lymph node, which includes iron oxide nanoparticles dispersed and stabilized in an aqueous medium by a mussel adhesive protein-mimetic copolymer, a method for contrast enhanced lymphography using the foregoing contrast agent, and a method for diagnosis of lymph node cancers using the foregoing contrast agent. Using such a mussel adhesive protein-mimetic copolymer, the surface of iron oxide is modified and dispersed well in water to prepare a colloidal solution, which in turn forms the contrast agent containing the colloidal solution. The inventive contrast agent does not have toxicity and is easily taken up to the lymph node to exhibit excellent contrast imaging effects. The contrast agent of the present invention is useful for diagnosis of metastatic cancers.
US08906337B2 Method for preparing graphene by using two-dimensional confined space between the layers of inorganic layered materials
The present invention relates to a method for preparing graphene using the two-dimensional confined space between the layers of inorganic layered materials. Such method comprises the following steps: mix a soluble salt of a divalent metal ion M2+, a soluble salt of a trivalent metal ion M′3+, a soluble salt of a chain alkyl anion A− and a carbon source molecule C and dissolve them in deionized and CO2-eliminated water to prepare a mixed salt solution; mix the mixed salt solution with an alkali solution under nitrogen protection and subject them to reaction and crystallization under nitrogen, and filter the suspension obtained thereafter and wash the filter cake with deionized water until the pH of the filtrate is 7 to 7.5, and then dry the filter cake to obtain layered double hydroxides with an intercalated structure; under an inert atmosphere or a reducing atmosphere, calcinate the layered double hydroxides with an intercalated structure to provide a calcinated product; add the calcinated product into a hydrochloric acid solution for ultrasonic treatment, and separate the solution by centrifugation and wash the precipitate obtained by centrifugation with deionized water until the pH of the filtrate is 6.5 to 7 to obtain the graphene.
US08906336B2 Blast furnace metallurgical coal substitute products and method
A carbonaceous material substitute product for blast furnace metallurgical coal and method of making the carbonaceous material is disclosed. A metallurgical coal substitute material is made from non-metallurgical grade coal or other carbon sources.
US08906335B2 System and method for broad-area synthesis of aligned and densely-packed carbon nanotubes
Broad-area synthesis of aligned and densely-packed carbon nanotubes (CNT) is disclosed. CNT are repeatedly synthesized and then drawn together to locally and globally achieve increased packing densities. The process synthesizes an aligned, relatively sparse forest of CNT on a catalyzed sacrificial substrate. The catalyst is removed, thereby releasing the CNT but leaving them in place on the substrate. A liquid-induced collapse produces regions of more densely packed CNT and regions where no CNT remain. A fresh catalyst is deposited on the exposed regions of the substrate and a sparse forest of aligned CNT is regrown in these regions. The CNT also may form on the tops of the densified regions of CNT. The top-growth CNT may be removed or incorporated into the solid such that the solid is expanded axially. This process, e.g., growth then densification, is repeated to form a near-continuous solid of aligned and densely packed CNT.
US08906334B2 High efficiency reactor and process
The invention includes an apparatus and process for the catalytic production of HCN from a feed gas of ammonia and a hydrocarbon gas by means of heat tubes supplying heat to the feed gas stream and heat tubes for removal of heat from the products. The invention further includes a process for N2O abatement comprising transferring heat from an exothermic N2O degradation reaction through a heat pipe.
US08906333B1 Dry scrubber system with air preheater protection
An air quality control system (AQCS) useful for treating flue gas, such as flue gas produced by a fossil fuel fired boiler, is described. In addition to flue gas treatment, the AQCS provides for air preheater flue gas outlet flue gas temperature reduction and air preheater corrosion prevention while reducing capital costs, increasing reliability and increasing operating flexibility with regard to fuel selection.
US08906330B2 Lean HC conversion of TWC for lean burn gasoline engines
The present invention relates to a catalyst composition comprising a carrier substrate, a layer (i) coated on said carrier substrate comprising at least one precious group metal, a layer (ii) comprising Rh, and a layer (iii) comprising Pd and/or Pt and being substantially free of Ce, Ba and Rh, wherein the layer (iii) has a lower weight than the layer (i) or the layer (ii). Furthermore, the present invention relates to a method for treating an exhaust gas stream using said catalyst composition.
US08906325B2 Vacuum assist for a microplate
A vacuum assist apparatus can comprise a microplate. The microplate can comprise a first surface and an opposing second surface. A plurality of wells can be formed in the first surface of the microplate. Each of the plurality of wells can be sized to receive an assay therein. A support base can comprise a fluid passage. The microplate can be positioned adjacent and in contact with the support base. A pressure device, in fluid communication with the fluid passage, can exert a vacuum within the fluid passage to actively retain the microplate in the contact with the support base.
US08906318B1 Feeding-bottle sterilizer
The present invention discloses a feeding-bottle sterilizer, comprising an upper cap, a base, and a container in which a feeding-bottle holder is placed, wherein an upper basket is arranged between the container and the upper cap, a baffle is arranged between the upper cap and the upper basket, a barrier is arranged between the base and the container, the baffle can slow down the steam flow out of the sterilizer, and a first, second, and third steam nozzle and a steam supply device are arranged on the base. The air cap of the first steam nozzle can rotate 360 degrees to ensure rapid and even steam distribution in space, the second steam nozzle stretches into the feeding bottle for sterilizing the feeding-bottle cavity, and the third steam nozzle extends into the upper basket. Furthermore, the feeding-bottle sterilizer has advantages of convenient cleaning, quick, and thorough sterilization.
US08906309B2 Method for discriminating red blood cells from white blood cells by using forward scattering from a laser in an automated hematology analyzer
A method for identifying, analyzing, and quantifying the cellular components of whole blood by use of an automated hematology analyzer and the detection of the light scattered, absorbed, and fluorescently emitted by each cell. More particularly, the aforementioned method involves identifying, analyzing, and quantifying the cellular components of whole blood by use of a light source having a wavelength ranging from about 400 nm to about 450 nm and multiple in-flow optical measurements and staining without the need for lysing red blood cells.
US08906304B2 Sample processing device, sample treatment method, and reaction container used in these device and method
Reaction containers (110) each comprising a plurality of treatment parts (wells) (501-506) are placed side by side in a reaction container set so as to be movable independently of each other in the direction of arrangement of the treatment parts (wells). A plurality of stems (401) correspond to the respective reaction containers (110) and are disposed above the reaction containers to be vertically movable and disposed in the direction crossing the direction of movement of the reaction containers. Control is performed so that when the reaction containers (110) and a stem mechanism (111) are operated together and one of the treatment parts (501-506) of each of the reaction containers (110) comes immediately below the stem mechanism (111) in accordance with a treatment procedure, a stem (401) corresponding thereto, a magnetic chip (402) attached thereto, or the cover (405) thereof can go into and out of the treatment part.
US08906302B2 Reagent preparing device, specimen measuring device and reagent preparing method
A reagent preparing device for preparing a reagent to be supplied to a measurement device for measuring a specimen, comprising: a first liquid storage unit for storing a first liquid; a reagent storage unit for storing a prepared reagent, including the first liquid and a second liquid different from the first liquid; a first liquid discarding unit for discarding the first liquid stored in the first liquid storage unit; and a controller configured for measuring an accumulated time of the first liquid in the first liquid storage unit; and controlling the first liquid discarding unit to discard the first liquid stored in the first liquid storage unit when the accumulated time reaches a predetermined time is disclosed. A specimen measuring device and a reagent preparing method are also disclosed.
US08906301B2 Combustion control system and method using spatial feedback and acoustic forcings of jets
A system is provided that includes a combustion system having a plurality of jets; a spatial monitoring system with a plurality of sensors disposed in a spatial grid within or downstream from the combustion system; and a control system configured to adjust a forcing frequency of at least one fluid jet in the plurality of fluid jets in response to sensor feedback from the spatial monitoring system.
US08906298B2 Method for protecting substrate
The present invention relates to a method for preventing or reducing contamination of a surface of a substrate, or protecting a surface of a substrate by making a surface of a substrate hydrophilic, by means of arranging, successively in relation to the substrate, a first layer containing a negatively-charged substance, and a second layer containing a positively-charged substance or containing a positively-charged substance and a negatively-charged substance on the surface of the substrate or in a surface layer of the substrate. In accordance with the present invention, a novel method for preventing or reducing adhesion of contaminants, and color degradation or color change of a substrate over time, can be provided.
US08906296B2 Oxidation resistant nickel alloy
The present invention relates to an oxidation resistant Nickel alloy, characterized in the following chemical composition (in % by weight): 4-7 Cr, 4-5 Si, 0.1-0.2 Y, 0.1-0.2 Mg, 0.1-0.2 Hf, remainder Ni and unavoidable impurities. A preferred embodiment has the following chemical composition (in % by weight): 6 Cr, 4.4 Si, 0.1 Y, 0.15 Mg, 0.1 Hf, remainder Ni and unavoidable impurities. This alloy has an improved oxidation resistance and good creep properties at high temperatures.
US08906292B2 Crucible and facecoat compositions
Crucible compositions and methods of using the crucible compositions to melt titanium and titanium alloys. More specifically, crucible compositions having intrinsic facecoats that are effective for melting titanium and titanium alloys for use in casting titanium-containing articles. Further embodiments are titanium-containing articles made from the titanium and titanium alloys melted in the crucible compositions. Another embodiment is a crucible curing device and methods of use thereof.
US08906291B2 Piston rod and cylinder seal device for aluminum bath crust breaker
A piston rod and cylinder seal device includes a cylinder defining a piston chamber extending between first and second cylinder heads. The second cylinder head has a spud receiving bore, a pressure passage communicating with the spud receiving bore, and a bore supply/vent passage. A first piston is disposed in the piston chamber. A piston rod is connected to the piston, the piston rod having a piston rod spud extending beyond the first piston and including a blind shaft receiving bore. A second piston slidably disposed in the blind shaft receiving bore has a seal member connected thereto. A contact member connected to the second cylinder head in the spud receiving bore has a central passage extending therethrough in communication with the bore supply/vent passage. The seal member when contacting the contact member acts to seal the central passage.
US08906290B2 Method for exchangeably fastening a refractory purge plug or sleeve
A container for molten metal has at least one opening in which a refractory nozzle brick is mounted. A refractory purge plug or a refractory sleeve defining an outlet opening is inserted in the nozzle brick opening. A defined gap is formed between the nozzle brick opening and the purge plug or the sleeve and is filled with a refractory mass, this mass consisting of a material which can be easily bored or milled out of the mass for the purpose of replacing the purge plug or the sleeve. In this manner, laborious cleaning steps can be avoided and the nozzle brick no longer risks being damaged.
US08906288B2 Process for producing SiC fiber-bonded ceramics
Provided is a process for producing dense SiC fiber-bonded ceramics excellent in heat resistance and having a shape hard to form by hot pressing such as an elongated shape. The process for producing SiC fiber-bonded ceramics composed of: inorganic fiber made of SiC; and interfacial layers mainly made of carbon includes vacuum-sealing a preform, prepared by forming specific silicon carbide-based inorganic fiber into a certain shape, into a capsule and hot-isostatic-pressing the preform. The process is characterized in that the ratio of the number of carbon atoms to the number of silicon atoms in the preform is 1.02 to 1.20, and before the hot isostatic pressing, the preform is heated in an inert gas atmosphere or a reducing gas atmosphere at a temperature of 1200° C. to 1800° C. to adjust the oxygen content in the inorganic fiber to 6.0% by weight or lower, and then the hot isostatic pressing is carried out.
US08906286B2 Intraluminal prostheses having polymeric material with selectively modified crystallinity and methods of making same
Methods of manufacturing polymeric intraluminal prostheses include annealing the polymeric material to selectively modify the crystallinity thereof. Annealing may be utilized to selectively modify various properties of the polymeric material of an intraluminal prosthesis, including: selectively increasing the modulus of the polymeric material; selectively increasing the hoop strength of the intraluminal prosthesis; selectively modifying the elution rate (increase or decrease) of a pharmacological agent subsequently disposed on or within the annealed polymeric material; selectively increasing/decreasing stress in the intraluminal prosthesis; and selectively modifying the polymeric material such that it erodes at a different rate.
US08906285B2 Electrohydrodynamic printing and manufacturing
An stable electrohydrodynamic filament is obtained by causing a straight electrohydrodynamic filament formed from a liquid to emerge from a Taylor cone, the filament having a diameter of from 10 nm to 100 μm. Such filaments are useful in electrohydrodynamic printing and manufacturing techniques and their application in liquid drop/particle and fiber production, colloidal deployment and assembly, and composite materials processing.
US08906284B2 Wrinkled adhesive surfaces and methods for the preparation thereof
A wrinkled adhesive surface is prepared by swelling a laterally confined elastomer layer with a polymerizable monomer composition. Swelling the elastomer layer spontaneously produces a wrinkled surface, and the wrinkles are then stabilized by polymerizing the polymerizable monomer composition. The stabilized wrinkled surfaces prepare by the method can exhibit substantially enhanced adhesion relative to smooth surfaces of the same material. The stabilized wrinkled surfaces can also exhibit adhesion that is repeatable through many cycles of contact with and separation from another surface. The adhesive characteristics of the stabilized wrinkled surfaces can be tailored by manipulating the size of the wrinkles.
US08906283B2 Stimuli-responsive surfaces and related methods of fabrication and use
Biomimetic stimuli-responsive surfaces and articles of manufacture, together with methods of fabrication and related methods of use.
US08906281B2 Imprint method, imprinting equipment, and method for manufacturing semiconductor device
In an imprint method according to one embodiment, a template on which a template pattern is formed is pushed against resist on a substrate to be transferred while the resist is cured in this state. The template is subsequently separated from the cured resist. The template is then degassed from the template pattern surface side between after the template is separated from the cured resist and till the template is pushed against resist at the next shot.
US08906279B2 Manufacturing method of polarizing plate protective film, polarizing plate protective film, polarizing plate, and liquid crystal display device
A process for producing a cellulose-ester-resin-containing protective film for polarizers through film formation by melt casting. The protective film diminishes long-period optical unevenness and suffers no unevenness even after long-term storage. Also provided are a protective film for polarizers, a polarizer employing the film, and a liquid-crystal display. The process for producing a protective film for polarizers is a process for producing by the melt casting method a polarizer-protective film containing a cellulose ester resin. The process for producing a protective film for polarizers is characterized in that the protective film contains at least one compound selected among compounds represented by the following general formula (I) and compounds having an acrylate or methacrylate group and a phenolic hydroxy group in the same molecule and that the protective film extruded from a casting die at a draw ratio of 10-30 during film formation by melt casting is transferred while holding/pressing it between a touch roll having an elastic surface and a cooling roll.
US08906276B2 Extrusion blow molded PET container and method of making
A plastic container that is fabricated from an extrudable polyethylene terephthalate (PET) using an extrusion blow molding process includes a neck portion, a bottom portion and a main body portion. The main body portion has a central opening that extends completely through the main body portion and may have generally toroidal area surrounding the central opening. The bottom portion includes a plurality of support feet and a substantially smooth central raised portion that has substantially no discontinuities such as the gate well that is commonly found on PET containers fabricated using the conventional stretch blow molding process. The neck portion may be offset from a longitudinal axis of the container so as to facilitate pouring by a consumer.
US08906275B2 Textured elements incorporating non-woven textile materials and methods for manufacturing the textured elements
A method of manufacturing a textured element may include (a) collecting a plurality of filaments upon a textured surface to form a non-woven textile and (b) separating the non-woven textile from the textured surface. Another method of manufacturing a textured element may include depositing a plurality of thermoplastic polymer filaments upon a first surface of a polymer layer to (a) form a non-woven textile and (b) bond the filaments to the polymer layer. A textured surface may then be separated from a second surface of the polymer layer, the second surface being opposite the first surface, and the second surface having a texture from the textured surface.
US08906274B2 Sealing material and method for preparing the same
A sealing material is provided, which has excellent sealing property, with cracks, fracture, and deformation being minimized. The sealing material of the invention is prepared by vulcanizing and foaming a mixture containing a rubber component containing a copolymer rubber of ethylene, an α-olefin having 3 or more carbon atoms, and a non-conjugated diene, a vulcanizing agent, and a blowing agent, and then subjecting the mixture to a cell breakage treatment, characterized in that the mixture further includes a fatty acid calcium salt and a fatty acid zinc salt.
US08906271B2 Photosensitive resin composition for color filter and color filter using the same
Disclosed is a photosensitive resin composition for a color filter and a color filter using the same. The photosensitive resin composition for a color filter includes (A) a dye-polymer composite including a structural unit derived from the compound represented by the following Chemical Formula 1, wherein each substituent is the same as defined in the detailed description; (B) an acryl-based photopolymerizable monomer; (C) a photopolymerization initiator; and (D) a solvent.
US08906269B2 Paste and solar cell using the same
The present invention relates to a paste and a solar cell using the paste. The paste according to an embodiment of the present invention comprises three and more than aluminum powders having different shape, size, and type, a glass frit, and an organic vehicle, wherein the aluminum powers includes a first powder of 40 to 50 wt %, a second powder of 20 to 30 wt %, and a third powder of 0.1 to 2 wt %, and the first to third powders have one or more than different shapes of a globular shape, a flat shape, a nano shape, and combinations thereof.
US08906268B2 Bimodal organ phantom and associated production method
A phantom for medical imaging instrumentation, the phantom including a first hydrogel matrix, said matrix containing additives for simulating the optical and acoustic properties of a living organ or tissue. In the phantom, the additives include Indian ink or haemoglobin, silica powder and titanium dioxide powder. The phantom may contain a tumor simulator in solid or liquid form. It may also comprise several hydrogel matrices, each matrix including additives in different concentrations depending on the organ or tissue simulated. A method of producing the phantom includes one or more freeze-thaw cycles for optimizing the characteristics of the phantom.
US08906263B2 Red nitride phosphors
Provided according to embodiments of the invention are phosphor compositions that include Ca1-x-ySrxEuyAlSiN3, wherein x is in a range of 0.50 to 0.99 and y is less than 0.013. Also provided according to embodiments of the invention are phosphor compositions that include Ca1-x-ySrxEuyAlSiN3, wherein x is in a range of 0.70 to 0.99 and y is in a range of 0.001 and 0.025. Also provided are methods of making phosphors and light emitting devices that include a phosphor composition according to an embodiment of the invention.
US08906261B2 Liquid crystal medium containing thiophene derivatives
The present invention relates to liquid-crystalline media (LC media) comprising thiophene derivatives and to liquid-crystal displays (LC displays) containing these LC media. The media have high optical anisotropy and preferably have a content of thiophene derivatives of 25% by weight or more.
US08906257B2 Composite getter for manufacturing photovoltaic panels
The present invention refers to a composite getter for thin-film photovoltaic panels which is made with a polymer having low H2O transmission containing one or more alkaline earth metal oxide, to a photovoltaic panel containing such composite getter and to a method for the manufacturing of photovoltaic panels.
US08906255B2 Lithium-ion secondary battery
The lithium-ion secondary battery in which a positive electrode contains Lia(M)b(PO4)cFd (M=VO or V, 0.9≦a≦3.3, 0.9≦b≦2.2, 0.9≦c≦3.3, 0≦d≦2.0) as an active material and 1 to 300 ppm of sulfur is used.
US08906254B2 Cathode material for secondary battery and manufacturing method of the same
Disclosed are a cathode material for a secondary battery, and a manufacturing method of the same. The cathode material includes a lithium manganese phosphate LiMnPO4/sodium manganese fluorophosphate Na2MnPO4F composite, in which the LiMnPO4 and Na2MnPO4F have different crystal structures. Additionally, the method of manufacturing the cathode material may be done in a single step through a hydrothermal synthesis, which greatly reduces the time and cost of production. Additionally, the disclosure provides that the electric conductivity of the cathode material may be improved through carbon coating, thereby providing a cathode material with excellent electrochemical activity.
US08906250B2 Lubricant composition for refrigerating machine and compressor using the same
A lubricating oil composition for refrigerator including a base oil and an acid scavenger, and a compressor using the composition are provided, where the acid scavenger is a polyalkylene glycol derivative represented by a formula (1) as follows: R1—[(OR2)e—OR3]f  (1) and the base oil is at least one compound selected from a group consisting of polyvinyl ether, polyalkylene glycol and an ether-base compound represented by a formula (2) as follows, Ra-[(ORb)n-(X)—(ORc)k]x-Rd  (2) where meanings of respective signs are as described in the specification.
US08906249B2 Plasma processing apparatus and plasma processing method
A plasma processing apparatus includes a beam-shaped spacer 7 which is placed at an upper opening of a chamber 3 opposed to a substrate 2 to support a dielectric plate 8. The dielectric plate 8 is supported by the beam-shaped spacer 7. In the beam-shaped spacer 7 are provided a plurality of process gas introducing ports 31, 36 which have a depression angle θd and which are provided downward and directed toward the substrate 2, as well as a plurality of rare gas introducing ports 41 having a elevation angle θe directed toward the dielectric plate 8. Improvement of processing rates such as etching rate as well as effective suppression of wear of the dielectric plate 8 can be achieved.
US08906248B2 Silicon on insulator etch
A method etching features through a stack of a silicon nitride layer over a silicon layer over a silicon oxide layer in a plasma processing chamber is provided. The silicon nitride layer is etched in the plasma processing chamber, comprising; flowing a silicon nitride etch gas; forming the silicon nitride etch gas into a plasma to etch the silicon nitride layer, and stopping the flow of the silicon nitride etch gas. The silicon layer is, comprising flowing a silicon etch gas, wherein the silicon etch gas comprises SF6 or SiF4, forming the silicon etch gas into a, and stopping the flow of the silicon etch gas. The silicon oxide layer is etched in the plasma processing chamber, comprising flowing a silicon oxide etch gas, forming the silicon oxide etch gas into a plasma, and stopping the flow of the silicon oxide etch gas.
US08906246B2 Film deposition apparatus and film deposition method
A film deposition method includes steps of transferring a substrate having a pattern including a concave part into a vacuum chamber; supplying a first reaction gas to the substrate from a first reaction gas supplying part, thereby allowing the first reaction gas to be adsorbed on the substrate; supplying a second reaction gas that reacts with the first reaction gas to the substrate from a second reaction gas supplying part, thereby allowing the first reaction gas adsorbed on the substrate to react with the second reaction gas and forming a reaction product of the first and the second reaction gases on the substrate; supplying an alteration gas to the substrate through an activated gas supplying part capable of activating the alteration gas; and supplying an etching gas to the substrate chamber through the activated gas supplying part under an environment where the reaction product is not formed.
US08906245B2 Material trivial transfer graphene
A method for transferring PMMA-coated graphene can transfer graphene to a wide variety of different substrate surfaces. It transfers graphene to different surfaces by using of Poly(methyl methacrylate) (PMMA), polymer such as sponge, and deionized (DI) water. This method comprises easy steps of coating CVD graphene with a layer of PMMA; placing the PMMA-coated CVD graphene onto a polymer to form a PMMA-coated CVD graphene on the surface of a polymer; putting this polymer with PMMA-coated CVD graphene in DI water, and finally scooping up the PMMA-coated CVD graphene with one target substrate. In this way, it transfers the CVD graphene to a target substrate surface.
US08906244B2 Method for forming a device having nanopillar and cap structures
A method for forming a device having nanopillar and cap structures on a substrate in which the substrate is first coated with a first resist having a first exposure dose to electron beam radiation, and that after coating the first resist with a second resist having a second exposure dose less than the first resist. Electron beam lithography is then used sequentially to form the nanopillars and cap structures or, alternatively, a template for the nanopillar and cap structures.
US08906243B2 Apparatus and process for treatment for immiscible liquids
The present invention relates to an apparatus for continuous treatment of two immiscible molten liquids having different densities. The apparatus comprises at least one open-ended helical reaction channel (3) arranged inside a substantially vertical housing (1), means for the continuous supply of the liquid with the higher density to the upper open end of said at least one reaction channel (3) and means for continuous supply of the liquid with the lower density to the lower open end of said at least one helical reaction channel (3), means for continuous removal of the liquid with the higher density at the lower open end of said helical reaction channel and means for removal of the liquid with the lower density from the upper open end of said helical reaction channel (3). The invention further relates to a method for continuous treatment of two immiscible molten liquids having different densities using the apparatus of the present invention.
US08906238B2 Fluid clarifier and method for clarifying a fluid
Liquid clarifier and method for clarifying liquid, comprising a liquid reactor which comprises an cylindrical tank having an upper vertical section and a lower tapered section, an inner cylinder extending along at least part of the upper section of the tank and an outlet for clarified liquid at the top of the tank, where the liquid clarifier further comprises a gas compressor adapted to inject compressed gas into the lower region of the cylinder and an inlet for an unclear liquid at the upper region of the cylinder, and at least one partition wall inside the cylinder, where the at least one partition wall create flow channels in the lower region of the inner chamber, where the compressed gas is adapted to be injected through gas inlets in flow channel/s in order to create an upward flow in the flow channel/s having gas inlets, which will create a downward flow in the flow channel/s without gas inlets, where the at least one partition wall extends out of the lower region of the cylinder. The advantage of the invention is that different kinds of liquids can be clarified in an efficient and fast way without the need of specific additives.
US08906233B2 Ring grit remover with vanes
A grit removal apparatus has a central opening between a cylindrical separation chamber above a grit storage chamber. An influent flume introduces a liquid stream directly into a lower portion of the periphery of the separation chamber, and an effluent flume removes a stream through an opening in an upper portion of the separation chamber wall. Outwardly spiraling vanes extend upwardly at the bottom center of the separation chamber, and a vertical cylindrical duct is supported above the vanes. A tunnel is defined in the separation chamber by an upper wall at the bottom of that opening and an inner wall concentric with the separation chamber wall. A ring extends inwardly from the separation chamber wall, with the tunnel upper wall defining a portion of the ring. A propeller inside the duct rotates to draw fluid flow up through the duct toward the upper portion of the separation chamber.
US08906230B2 Apparatus for treating a waste stream
An integrated unit operations for the treatment of a waste stream, such as spent caustic, is provided in a single vertical vessel having at least three separate zones: a mixing, a settling, and a mass transfer zone.
US08906227B2 Mild hydrodesulfurization integrating gas phase catalytic oxidation to produce fuels having an ultra-low level of organosulfur compounds
Desulfurization of hydrocarbon feeds is achieved by first contacting the entire feed with a hydrodesulfurization catalyst in a hydrodesulfurization reaction zone operating under mild conditions; a flashing column downstream of the hydrodesulfurization reaction zone fractionates the effluent to obtain a first fraction which contains refractory organosulfur compounds and a second fraction that is substantially free of organosulfur compounds, since the organosulfur compounds boiling in the range of this fraction were the labile organosulfur compounds which were initially removed by mild hydrodesulfurization. The first fraction is contacted with a gaseous oxidizing agent over an oxidation catalyst having a formula CuxZn1-xAl2O4 in a gas phase catalytic oxidation reaction zone to convert the refractory organosulfur compounds to SOx and low sulfur hydrocarbons. The by-product SOx is subsequently removed, producing a stream containing a reduced level of organosulfur compounds.
US08906226B2 Process for increasing aromatics production
A process for reforming a hydrocarbon stream is presented. The process involves splitting a naphtha feedstream to at least two feedstreams and passing each feedstream to separation reformers. The reformers are operated under different conditions to utilize the differences in the reaction properties of the different hydrocarbon components. The process utilizes a common catalyst, and common downstream processes for recovering the desired aromatic compounds generated.
US08906225B2 Metallophosphate molecular sieves, methods of preparation and use
A new family of crystalline microporous metallophosphates designated AlPO-57 has been synthesized. These metallophosphates are represented by the empirical formula R+rMmn+EPxSiyOz where R is an organoammonium cation such as the DEDMA+, M is a divalent framework metal such as an alkaline earth or transition metal, and E is a framework element such as aluminum or gallium. The microporous AlPO-57 compositions are characterized by a new unique ABC-6 net structure and have catalytic properties for carrying out various hydrocarbon conversion processes and separation properties for separating at least one component.
US08906223B2 High temperature reforming process for integration into existing units
A process is presented for increasing the aromatics content in a reformate process stream. The process modifies existing processes to change the operation without changing the reactors or heating units. The process includes bypasses to utilize heating capacity of upstream heating units, and passes the excess capacity of the upstream heating units to downstream process streams.
US08906221B2 Electrochemical grinding tool and method
An electrochemical grinding tool and method capable of rounding sharp edges that may be prone to cracking, for example, edge regions of cooling slots within dovetail slots of turbine wheels. The electrochemical grinding tool includes a drilling assembly, a conductive bit, and a motor for rotating the conductive bit about an axis thereof. The conductive bit of the electrochemical grinding tool is inserted into a first slot, an electrolyte solution is applied between the conductive bit of the electrochemical grinding tool and a second slot that intersects the first slot, an electrical potential is applied to the conductive bit and the turbine wheel to create a potential gradient between the conductive bit and the edge of the second slot, and material is removed from the edge of the second slot by displacing the conductive bit about and along the edge.
US08906220B2 Method for production of metallic cobalt from the nickel solvent extraction raffinate
Method for production of metallic cobalt from the raffinate from solvent extraction of nickel’. Said method comprises the following stages: (A) obtaining the raffinate from solvent extraction of nickel, for production of cobalt; (B) adding a sulfide precipitation agent to said raffinate, for cobalt sulfide and zinc sulfide precipitation; (C) removing all ammonia from the sulfidized pulp (solids and liquid); (D) subjecting the filtered solid—cobalt sulfide (and impurities)—to atmospheric leaching; (E) reducing to a minimum the zinc concentration in the cobalt round, by means of solvent extraction with D2EPHA extractant diluted in solvent, in any solvent extraction system comprising the required number of extraction, scrubbing, and stripping stages, with resident time of not less than 1 minute at each of the stages used; (F) performing nickel removal by ion exchange, for nickel purification; (G) adding sodium carbonate to the solution, for cobalt carbonate precipitation; (H) leaching the produced cobalt carbonate in a system that utilizes an acid, preferably sulfuric acid, and more preferably, the anolyte from cobalt electrolysis; (I) performing cobalt electrowinning so as to recover the cobalt from the solution in its metallic form; and (J) allowing the metallic cobalt to settle on insoluble stainless steel plates during the time required for production of the cobalt cathodes.
US08906219B2 Methods and apparatus of electrochemical production of carbon monoxide, and uses thereof
The present invention relates to an electrolytic process, methods and apparatus for the preparation of carbon monoxide and in particular to electrolysis of molten carbonates to yield carbon monoxide which may be used for chemical storage of electrical energy and further as chemical feedstock for other organic products.
US08906218B2 Apparatus and methods for uniformly forming porous semiconductor on a substrate
This disclosure enables high-productivity controlled fabrication of uniform porous semiconductor layers (made of single layer or multi-layer porous semiconductors such as porous silicon, comprising single porosity or multi-porosity layers). Some applications include fabrication of MEMS separation and sacrificial layers for die detachment and MEMS device fabrication, membrane formation and shallow trench isolation (STI) porous silicon (using porous silicon formation with an optimal porosity and its subsequent oxidation). Further, this disclosure is applicable to the general fields of photovoltaics, MEMS, including sensors and actuators, stand-alone, or integrated with integrated semiconductor microelectronics, semiconductor microelectronics chips and optoelectronics.
US08906215B2 Field effect based nanosensor for biopolymer manipulation and detection
A mechanism is provided for manipulating a molecule. The molecule is driven into a nanochannel filed with electrically conductive fluid. A first vertical electric field is created inside the nanochannel to slow down the molecule and/or immobilize the molecule. The molecule is stretched into non-folded linear chains by the first vertical electric field and a horizontal electric field. Monomers of the molecule are sequentially read.
US08906211B2 Cationic polymer based wired enzyme formulations for use in analyte sensors
Embodiments of the invention include analyte-responsive compositions and electrochemical analyte sensors having a sensing layer that includes an analyte-responsive enzyme and a cationic polymer. Also provided are systems and methods of making the sensors and using the electrochemical analyte sensors in analyte monitoring.
US08906209B2 Auto-calibrating test sensor and method of making the same
An electrochemical test sensor (10) for determining an analyte in a fluid sample, includes a base (12) and a second layer. The base (12) includes a plurality of electrodes (30,32), a working conductive lead (42) and a counter conductive lead (40) thereon. The electrodes include a working electrode (32) and a counter electrode (30). The second layer (20) assists in forming a channel (22) in which the channel includes a reagent therein. Auto-calibration information of the test sensor is performed by a plurality of auto-calibration segments (75) connected to one of the following: the working conductive lead (42), the counter conductive lead (40), or neither of the conductive leads, at least one of the plurality of auto-calibration segments (75a) being connected to the working conductive lead (42) and at least one of the plurality of auto-calibration segments (75b) being connected to the counter conductive lead (40).
US08906208B2 Sputtering apparatus, sputtering method, and electronic device manufacturing method
A sputtering apparatus includes a substrate holder which holds a substrate to be rotatable in the plane direction of the processing surface of the substrate, a substrate-side magnet which is arranged around the substrate and forms a magnetic field on the processing surface of the substrate, a cathode which is arranged diagonally above the substrate and receives discharge power, a position detection unit which detects the rotational position of the substrate, and a controller which controls the discharge power in accordance with the rotational position detected by the position detection unit.
US08906201B2 Use of acidic water in the manufacture of paper
The present invention relates to a method of manufacturing paper or cardboard, wherein paper or board pulp is diluted with an aqueous composition, which is formed from colloidal-size particles of carbonate and bicarbonate, and other states of carbonate in an aqueous solution, so that the pH in the aqueous solution remains essentially at a value of 6.0-8.3 during the formation, and water is removed from the pulp by draining, pressing, and drying. The invention also relates to a method of manufacturing the aqueous composition used for this purpose.
US08906197B2 Plasma processing chamber having electrodes for cleaning chamber
Plasma processing chamber having a bottom electrode assembly is disclosed. The assembly has an inner bottom electrode for supporting a substrate and an outer bottom electrode disposed outside of the inner bottom electrode. The outer bottom electrode defines a region for chamber cleaning, and the outer bottom electrode includes a conductive ring and an inductive coil placed under the conductive ring. Further included is a dielectric material disposed between the inner bottom electrode and the outer bottom electrode, and the dielectric material separates the inner bottom electrode from the outer bottom electrode. A switch is provided for connecting radio frequency (RF) power to either the inner bottom electrode or the outer bottom electrode. The chamber also includes a top electrode assembly with a top electrode. The top electrode is disposed above both the inner and outer bottom electrodes.
US08906189B2 Method of adhesively bonding a strip of flexible fabric to a substrate
The invention relates to a method of bonding a strip of flexible sheet onto at least one flexible or rigid support, said sheet and said support including at least one continuous fine metal foil sandwiched and bonded between two fiberglass fabrics. In accordance with the invention, the method includes a step of pressing said strip of flexible sheet against the support by means of a press while simultaneously heating said strip for at least a portion of the duration over which pressure is applied.
US08906187B2 Method of making shoulder/nozzles with film barrier liners
The method comprises an automated technique for making and inserting flexible laminate film barrier liners into the shoulder/nozzles of product tube packaging. The shoulder/nozzles are made and oriented with the shoulder opening to be facing the laminate film. The film is fed to a station that forms the nozzle aperture, die cuts the laminate film to fit into the shoulder of the shoulder/nozzle, and inserts this laminate film into the shoulder/nozzle. The laminate film can be heat bonded to the shoulder nozzle at this station or in a subsequent sealing station. After the shoulder/nozzle leaves the station that forms and inserts the laminate film into the shoulder/nozzle there can be a detection station to determine if the laminate film is properly aligned in the shoulder/nozzle. There also can be a detection station after a subsequent sealing station. Shoulder/nozzles with sealed laminate film liner are then sent to tube making. The laminate film will have a polymer layer and a barrier layer comprising ethylene vinyl alcohol copolymers, polyethylene terephthalate polymers, polyethylene naphthalate polymers and acrylonitrile methyl-acrylate copolymers The tube packages produced using these shoulder/nozzles are very useful for products which contain flavorants, such as dentifrices.
US08906179B2 Systems, tools, and methods for forming composite tubular stringers and stiffened composite structures having composite tubular stringers
Systems, tools, and methods for forming composite tubular stringers and stiffened composite structures having composite tubular stringers are disclosed. Systems include a tool, a supply of pliable blanks for forming composite tubular stringers with the tool, a supply of skin segments for forming a skin, and a layup mandrel for receiving the composite tubular stringers and the skin to form a stiffened composite structure. Tools include a wrapping mandrel for forming from a pliable blank a tubular structure with a first circumferential profile, and a transition mandrel for conforming the tubular structure to a second circumferential profile. Methods include wrapping a pliable blank around a wrapping mandrel to define a tubular structure having a first circumferential profile, and transitioning the tubular structure from having the first circumferential profile to having a second circumferential profile.
US08906165B2 Substrate processing method, storage medium storing computer program for performing substrate processing method, and substrate processing apparatus
In a substrate processing method according to the present invention, a substrate is first processed using a chemical liquid. Next, the substrate is rinsed by supplying a rinsing liquid thereto while the substrate is being rotated. Thereafter, the substrate is dried while the substrate is being rotated. The drying of the substrate includes reducing a rotating speed of the substrate to a first rotating speed lower than that of the substrate during the rinsing of the substrate, while supplying the rinsing liquid to a central portion of the substrate; moving, from the central portion of the substrate toward a peripheral edge portion thereof, a rinsing liquid supply position to which the rinsing liquid is supplied, after the rotating speed of the substrate has been reduced to the first rotating speed; and supplying a drying liquid to the substrate, after the rinsing liquid supply position has been moved.
US08906162B2 Metal organic chemical vapor deposition equipment
Metal organic chemical vapor deposition equipment is metal organic chemical vapor deposition equipment for forming a film on a substrate by using a reactant gas, and includes a susceptor heating the substrate and having a holding surface for holding the substrate, and a flow channel for introducing the reactant gas to the substrate. The susceptor is rotatable with the holding surface kept facing an inner portion of the flow channel, and a height of the flow channel along a flow direction of the reactant gas is kept constant from a position to a position, and is monotonically decreased from the position to the downstream side. It is thereby possible to improve film formation efficiency while allowing the formed film to have a uniform thickness.
US08906155B2 Clinker substitute based on calcined clay
A method for producing a clinker substitute for use in cement production includes predrying clay with an iron content >1.5 wt-% in a form of iron oxides and a kaolinite content <40 wt-% to a moisture <10 wt-%. The clay is comminuted to a grain size <2 mm. The clay is calcined by thermal treatment in a furnace at a temperature of 600 to 1000° C. The clay is thermally treated under reducing conditions at a temperature of 600 to 1000° C. so as to form a reduction product. The reduction product is intermediately cooled to a temperature <300° C. and finally cooled.
US08906152B2 Reclaimed asphalt pavement containing polyphosphoric acid modified binder
Pavement compositions containing increased amounts of reclaimed asphalt pavement (RAP) are described. Addition of polyphosphoric acid (PPA) to pavement compositions containing RAP allows increased RAP content in road pavements while maintaining acceptable properties in the final pavement composition. Methods for producing road pavements containing RAP and PPA are also provided.
US08906148B2 Bubble generator for valve or faucet
A bubble generator includes a housing engaged in a receptacle, and a casing engaged into the housing and having an outer peripheral fence and a bottom plate, and having a bulge extended upwardly from the bottom plate for forming an inner peripheral channel between the bulge and the peripheral fence, and having a passage formed in the peripheral fence and communicating with the inner peripheral channel of the casing for allowing a fluid to flow into the inner peripheral channel of the casing and to flow out through the passage of the casing and to flow into the compartment of the housing, and the casing includes a number of projections extended from the bulge for agitating the fluid and for generating air bubbles in the fluid.
US08906145B2 Compressed air supply device for a utility vehicle and air dryer cartridge
A compressed air supply device is provided for a utility or commercial vehicle. The device includes a valve housing and an air dryer cartridge which has a housing. A drying agent box, which is filled with drying agent, is arranged in the housing of the air dryer cartridge. The drying agent can be compressed by an elastic device.
US08906139B2 Method for selectively isolating hydrogen or helium using a natrolite-based zeolite, and novel natrolite-based zeolite
The present invention relates to selectively isolating gases using a natrolite-based zeolite, and more particularly, to a novel natrolite-based zeolite and to selectively isolating hydrogen and/or helium gas using a natrolite-based zeolite. The present invention is characterized in that gas containing hydrogen is brought into contact with a natrolite-based zeolite to selectively isolate the hydrogen. The present invention provides a sorbent which can selectively isolate hydrogen and/or helium, and provides a method for isolating the hydrogen and/or helium at room temperature or at a high temperature.
US08906135B1 Method of purifying a gas stream using 1,2,3-triazolium ionic liquids
A method for separating a target gas from a gaseous mixture using 1,2,3-triazolium ionic liquids is presented. Industrial effluent streams may be cleaned by removing carbon dioxide from the stream by contacting the effluent stream with a 1,2,3-triazolium ionic liquid compound.
US08906133B2 Process and plant for cooling sulfuric acid
A process for cooling an acid that is withdrawn from an absorption apparatus of a sulfuric acid plant includes pumping the acid to be cooled from an acid pump tank and supplying the acid to a shell space of a heat exchanger. Water is supplied as a heat transport medium to heat transfer elements disposed in the shell space so as to at least partially convert, by heat transfer from the acid, the water to steam. The acid which was cooled in the heat exchanger is supplied back to the absorption apparatus. The water is separated from the steam in a steam drum. The separated water is recirculated to the heat exchanger using a pump.
US08906131B2 Direct production of iron slabs and nuggets from ore without pelletizing or briquetting
Metallic iron is produced from a composition formed from a mixture of iron ore particles and particles of a reductant made of a biomass material, a coal or coke in a particulate form together with a flux and is processed in a loose, un-agglomerated non-pelletized, non-briquetted form in a reducing furnace to produce metallic iron directly from the ore. An excess of biomass or coal or coke reductant can be used to provide CO and H that can be recovered as a synthetic gas and converted to electrical or other energy. Metallic iron nuggets or slabs can be produced from manganiferous ores or concentrates. Manganese can be caused to enter the nugget or slab or the slag by adjusting the furnace temperature. Titaniferous ores or concentrates can be used to produce metallic iron slabs or nuggets and a titanium-rich slag.
US08906126B2 Filter system
The present disclosure relates to a fabric filter system, which may be used for removing particulate matter from a gas, such as a combustion process gas. The fabric filter system includes fabric filters (3) in a filter module. From the fabric filters (3), gas flows through a filter plenary space (5) and into an outlet duct (7). A flow control device (17) controls the amount of gas flowing into and through the outlet duct (7). The flow control device (17) comprises a guillotine-type damper (17). The guillotine-type damper (17) provides reliable and efficient control of the gas flow from the filter plenary space (5) into the outlet duct (7). A collar (21), fluidly connecting the filter plenary space with the outlet duct, improves the gas flow into the outlet duct (7).
US08906125B2 Catch box
A catch box may include two air intake sections of an air intake system, wherein the catch box is embodied as water separator at the same time.
US08906122B2 Coal processing operation comprising a dense media separation stage to separate a coal feedstock into lower and higher ash coal streams
A coal processing operation (10) includes in a dense media separation stage (12), subjecting a coal feedstock (18) which includes minerals to dense media separation producing a first coal stream (20) and a second coal stream (22). Coal in the first coal stream (20) is lower in ash and has a lower ash fusion temperature than coal in the second coal stream (22). Coal from the first coal stream (20) is processed in a high temperature coal processing operation (44), and coal from the second coal stream (22) is processed in a medium temperature coal processing operation (16).
US08906116B2 Mixtures of disperse dyes
The present invention relates to dye mixtures which comprise at least one dye of the formula (I) and at least one dye of the formula (II) in which R1, R2, R3, and X are defined as stated in claim 1, to processes for their preparation, and to their use.
US08906104B2 Knee prosthesis with rotatable post
A method of assembling a knee joint prosthesis for replacing a portion of a knee joint. The method includes rotatably coupling a post to an extension portion of an insert extending from a bearing member, and coupling a femoral component for articulation on the bearing member.
US08906103B2 Shoulder prosthesis
A prosthesis may include a stem, an adaptor and a head. The stem may include a longitudinal axis. The adaptor may include a first taper having a first taper axis of symmetry. The head may be rotatably supported by the adaptor and may include a semispherical articulating surface defined by a central axis of symmetry that is angled relative to the first taper axis of symmetry. The head may be coupled to the first taper and may be positionable relative to the stem through relative rotation between the head and the stem about the first taper axis of symmetry to adjust a radial offset of the head relative to the longitudinal axis of the stem. The head may be adapted to be received in a glenoid cavity of a scapula.
US08906098B2 Devices for introduction into a body via a substantially straight conduit to form a predefined curved configuration, and methods employing such devices
A device for introduction into a body in a straight configuration and assuming within the body a predefined curved configuration, includes an elongated element formed from a number of segments interconnected so as to form effective hinges therebetween. When the elongated element is confined to a straight state, the effective hinges transfer compressive forces from each segment to the next so that the elongated element can be pushed to advance it through a conduit. When the elongated element is not confined to a straight state, the effective hinges allow deflection of each segment relative to adjacent segments until abutment surfaces of the segments come into abutment, thereby defining a fully flexed state of the elongated element with a predefined curved configuration. The device can be produced with a wide range of two-dimensional and three-dimensional curved forms, and has both medical and non-medical applications.
US08906096B2 Spinal implant
An intervertebral disc prosthesis for installation in, a spinal column includes a first intervertebral plate for engaging one or both of the inferior vertebral endplate and the inferior ring apophysis of a superior vertebral body. A second intervertebral plate for engages one or both of the superior vertebral endplate and the superior ring apophysis of an inferior vertebral body. A removable insert core is located between and engages the intervertebral plates. A projection projects from one of the intervertebral plates toward the other intervertebral plate. The removable insert core at least partially surrounds the projection when installed. The removable insert core is removable from between the intervertebral plates and from around the projection while the intervertebral plates and projection remain installed.
US08906095B2 Spinal implant, instrument for preparation and method of use
The present disclosure relates to the field of spine disc implants. Exemplary embodiments of the disclosed spinal disc implants advantageously and ultimately provide fusion with the body of the vertebra and stabilization of the spine in an anatomically correct position, e.g., in cervical, thoracic and/or lumbar regions. More particularly, the present disclosure is directed to a disc implant that addresses and overcomes the shortcomings of the prior implants by providing first and second inter-vertebral elements that are movably coupled relative to each other and are adapted to permit bone in-growth over time. Thus, the disclosed spinal disc implants permit relative movement between the first and second inter-vertebral elements upon implantation and after the patient is mobilized—thereby permitting the implant to assume a desired position based on the specific and unique spinal balance of the patient in an initial post-implantation period—but then the first and second inter-vertebral elements become fixed relative to each other (i.e., fused). The present disclosure also provides advantageous instrumentation and associated methods for positioning a spine disc implant in a desired anatomical location.
US08906091B2 Component and method for assembling an implant arrangement
A component for an arrangement at an implant includes a sensor detecting a measurement variable and generating measuring data corresponding to the detected measurement variable; telemetry device transmitting data; a data transmission connection between the sensor and the telemetry device for the transmission of the measuring data therebetween; and an assembly arrangement detachably mounting the component in an implant recess of the implant wherein the component is configured to be insertable through an implant recess of an implant positioned over a target portion of a bone so that the component extends through the opening toward an outer periphery of the target portion of the bone.
US08906090B2 Auditory ossicle prosthesis
An auditory ossicle prosthesis, which at one end has a first securing element for mechanical connection to a member of the ossicular chain, which securing element is designed in the form of a loop that encloses the member, is partially open to the outside via a slit-like aperture and engages with a force fit around the member, the slit-like aperture being considerably smaller than the diameter of the member engaged by the loop, wherein, after attachment, the loop bears with a force fit on the engaged member via at least three areas, and that, in the circumferential direction around the engaged member, at least three areas of the loop do not touch the engaged member but instead each extend at a distance from the surface of the latter.
US08906088B2 Variable focus ophthalmic device including liquid crystal elements
This invention discloses methods and apparatus for providing a Variable Optic Insert into an Ophthalmic Lens. An energy source is capable of powering the Variable Optic Insert included within the Ophthalmic Lens. In some embodiments, an Ophthalmic Lens is cast-molded from a silicone hydrogel. The various Ophthalmic Lens entities may include electroactive Liquid Crystal layers to electrically control refractive characteristics.
US08906081B2 Stented vascular graft
A vascular graft incorporating a stent into a portion of its length. While various materials may be used for the vascular graft, the graft is preferably an ePTFE graft. The stent is preferably a self-expanding stent, although it may alternatively be a balloon expandable stent. The vascular graft preferably has a continuous inner tubular liner that extends between the opposing ends of the graft and provides a continuous luminal surface for blood contact that is uninterrupted by seams or joints. The length portion of the graft that does not include the stent has a greater wall thickness than does the portion including the stent.
US08906080B2 System and method for vessel access closure
Embodiments are described for closing vascular access ports, such as arteriotomies, which involve placement and deployment of an expandable device configured to prevent blood flow across a subject arteriotomy while also keeping disturbance of intravascular flow to a minimum. Suitable prostheses may comprise one or more frames constructed from lengths of flexible materials, such as shape memory alloys or polymers. Such frames may be coupled to sheetlike or tube-like structures configured to spread loads, minimize thrombosis which may be related to intravascular flow, and maintain hemostasis.
US08906079B2 Method/device for transdermal vascular treatment
Devices and transdermal methods are provided for safe and effective therapeutic treatment of the venous system, such as varicose veins. Present invention provides non-invasive and minimally invasive transdermal methods for treating varicose and spider veins, comprising the use of a radiation source in combination with a chemical fluid/composition to safely and more effectively close or shrink vein walls, providing a transdermal therapeutic method for varicose veins until now only treated with surgery or endovascular laser treatments. In a preferred embodiment a device comprises a radiation source, preferably of wavelength between about 980 and 1940 nm, being effective in causing shrinkage of the vein treated. In other preferred embodiments methods comprise the transdermal delivery of a chemical composition through a patch or gel or the injection of a chemical fluid, preferably a hypertonic solution, to the vein under treatment; and simultaneously or after a dwell time, irradiating with a radiation source transdermally. The treatment performed with the present invention results in blood vessel wall damaged, eventually closing the vein, in lesser time with practically no pain or discomfort to the patient during and after the therapy.
US08906075B2 Methods and assemblies for aligning a bone fixation plate
A bone fixation assembly is provided, including a bone fixation plate that has a plurality of apertures having different cross-sectional dimensions, and a temporary fixation wire. The temporary fixation wire includes an abutment member that can compress the bone fixation plate against an underlying bone so that the alignment of the bone fixation plate on the bone can be analyzed prior to using bone fixation members to permanently attach the bone fixation plate to the underlying bone.
US08906074B2 Expandable bone fixation implant
Bone fixation devices, assemblies, and methods are provided. An expandable bone fixation implant can be implanted into a patient and attached to an underlying bone via a percutaneous or alternative fixation procedure in order to provide fixation and stabilization of the underlying bone.
US08906073B2 Low profile periarticular tension band plating system with soft tissue neutralization cable tunnel/channel for use on the greater tuberosity of the humerus
A bone plating system comprising: a plate, where the plate is low-profile and capable of contouring to a bone; a variable number of screw holes, locking or non-locking; at least one channel or tunnel through the plate; and at least one flexible device passing through the channel or tunnel and passing through soft tissue attached to the bone. The low profile plate, in combination with the flexible device passing through the surrounding soft tissue, functions as a tension band and acts to neutralize the muscle forces tending to pull the bone apart at a fracture. The low profile tension band plating system is targeted for periarticular tensile fractures for repair of the greater tuberosity of the humerus.
US08906071B2 Low profile periartiular tension band plating system with soft tissue neutralization cable tunnel/channel for use on the olecranon
A bone plating system comprising: a plate, where the plate is low-profile and capable of contouring to a bone; a variable number of screw holes, locking or non-locking; at least one channel or tunnel through the plate; and at least one flexible device passing through the channel or tunnel and passing through soft tissue attached to the bone. The low profile plate, in combination with the flexible device passing through the surrounding soft tissue, functions as a tension band and acts to neutralize the muscle forces tending to pull the bone apart at a fracture. The low profile tension band plating system is targeted for periarticular tensile fractures for repair of the olecranon.
US08906070B2 Bone fixation device and method
For fixation of an oblique fracture in a long bone, a fixation plate is placed along the bone across the fracture and tabs extending outwardly from the plate engage the bone at upper and lower surfaces respectively of the proximal and distal fragments of the bone. By applying compressive force to the bone by the tabs, the fragments are subjected to compression force across the fracture and to a torque which opposes bone shortening.
US08906069B2 Transforaminal prosthetic spinal disc apparatus
An intervertebral prosthetic implant having a first endplate having a first surface configured to substantially engage with a first vertebral body and a second surface having an extension with a concave contact surface, the concave contact surface being spaced apart from the second surface. A second endplate is provided with a first surface configured to substantially engage with a second vertebral body and a second surface comprising a convex contact surface, and the second endplate having a securing element positioned along and above the second surface defining a first and second window on opposing sides of the second surface. The securing element extends along the width and length of the lower endplate and configured with an access hole. An extension portion extends from the first surface of the first endplate through the access hole of the securing element and contacts the second surface of the second endplate.
US08906068B1 Spinal fixation system and method
A spinal fixation system (1) for use in the fixation of a spine having a securing element (18) having a biasing member (21) located on a lower portion (44) of the securing element (18); and a substantially concave surface (25) dimensioned for at least partially circumscribing a fixation rod (15); and a retaining element (22) having: a substantially concave top surface (23) dimensioned for at least partially circumscribing a fixation rod (15); an outwardly extending wing (16); a crimping portion (42), wherein the crimping portion (42) at least partially compresses when a force is exerted on the retaining element (22); and a substantially concave bottom surface (24) dimensioned for at least partially circumscribing a head (11) of a bone fixation element (9).
US08906067B2 Posterior incremental spinal fixation system
A spinal fixation device may include a bone anchoring member, a rod receiver, and an connection member. The rod receiver may include a channel for receiving a rod projection from a first adjacent fixation assembly. The rod receiver may have a central axis such that the channel is generally perpendicular to the central axis. The connection member may have a rod projection configured to extend to a second adjacent fixation assembly. The rod receiver may be coupled to the connection member and rotatable about the central axis of the rod receiver. The interior fixation assembly may be axially fixed such that the bone anchoring member, the rod receiver and the connection member are not translatably movable relative to each other.
US08906065B2 Inter-spinous process device and method
An implantable device and method for fixation of spinous processes is presented. The device has first and second spaced plates, the first plate having a surface facing a surface of the second plate. The plates are configured for placement on either side of two adjacent spinous processes. The plates are held in place adjacent each side of the two spinous processes by a post connected to each of the plates and extending substantially therefrom the facing surface of the first plate to at least the facing surface of the second plate.
US08906063B2 Spinal facet joint implant
Superior and/or inferior facets of one or more facet joints may be replaced by superior and/or inferior facet joint prostheses. In one embodiment, a kit of superior or inferior prostheses is provided, in which the prostheses have at least two dimensions that vary among members of the kit independently of each other. Each prosthesis may have a bone engaging surface having a surface that is polyaxially rotatable against a corresponding resection of a vertebra. Each prosthesis may also have an articulating surface shaped such that, after attachment to the spine, the replaced or partially replaced facet joints provide a larger medial-lateral range of motion when the spine is flexed than when the spine is extended. Crosslinks may be used to connect left and right prosthesis together in such a manner that they are stabilized in a position in which they are seated directly against the vertebra.
US08906062B2 Apparatus for securing a spinal rod system
The present invention includes an apparatus for securing a spinal rod with an anchoring device, the apparatus including a tubular body defining a longitudinal axis from a proximal end to a distal end; a connecting element positioned within the tubular body and along the longitudinal axis, the connecting element engaged by a first internal shaft and a second internal shaft, the tubular body, first internal shaft and second internal shaft coaxial with one another; the first internal shaft rotatably engages the connecting element such that rotation of the first internal shaft results in axial translation of the connecting element; and the second internal shaft engages the connecting element such that rotation of the second internal shaft results in rotation of the connecting element.
US08906061B2 Hygienic pacifier
A device (1) for protecting a pacifier (2) includes: —a housing (3) for the pacifier, the pacifier having an external position where the pacifier is outside of the housing, the pacifier having an internal position where the pacifier is situated inside the housing; —an orifice (6) allowing the pacifier (2) to move from its internal position to its external position and from its external position to its internal position; and —elements (4, 40) for applying a return force (5) to the pacifier, the return force drawing the pacifier from its external position to its internal position. A method employed in this device is described. The pacifier is thus protected from dirt, germs and microbes and therefore the hygiene of the pacifier is improved.
US08906057B2 Aneurysm embolization by rotational accumulation of mass
This invention is a device and method for reducing blood flow into an aneurysm, especially a cerebral aneurysm, in order to promote therapeutic embolization of the aneurysm. The device comprises: at least one core member that is inserted into the aneurysm; and at least one longitudinal flexible member that is wound repeatedly around the core member within the aneurysm. The longitudinal flexible member is wound around the core member until the rotational accumulation of the flexible member reduces blood flow into the aneurysm and promotes therapeutic embolization of the aneurysm.
US08906056B2 Access trocar and related method thereof
System and method that is directed to medical treatments of organs having anatomical spaces, such as (but not limited to) the heart and the pericardial space. Specifically, an apparatus and method is provided for safely accessing anatomical spaces with surfaces to deliver medical devices or media into such spaces, or to remove fluids from such spaces. The methods and apparatus may include a first elongated member with a sharp tip used to penetrate the surface surrounding the anatomical space with a second elongated member with a helical tine used to engage the surface and lift the surface away from the underlying anatomical space. Once the first elongated member has incised the surface, it is removed, and the incision may be used as a point of entry for delivering media or medical devices into the anatomical space, or for carrying out further medical procedures.
US08906054B2 Apparatus for reducing the appearance of cellulite
A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece. The device and method cut the fibrous structures under the skin that cause cellulite at an angle substantially parallel to the surface of the skin and replace these structures with a non-cellulite forming structure by deploying a highly fibrous mesh through a single needle hole to create a highly fibrous layer directly or through wound healing processes.
US08906053B2 Systems and methods for surgical removal of brain tumors
A method for treating a brain tumor includes providing a surgical instrument having an inner member and an outer member. The outer member has a distal region forming a cutting window and an optional distal elevator tip. The inner member is rotatably received within the outer member, and has a cutting tip that is exposed at the window. The cutting tip and the distal region of the outer member combine to define a cutting implement. An opening is created through the patient's skull to provide access to a brain tumor target site. The cutting implement is delivered through the opening to the target site. The elevator tip is inserted partially between the tumor and tissue of the target site, and the cutting tip is placed into contact with the tumor and operated to cut the tumor. The target site is selectively aspirated to remove cut tumor tissue.
US08906051B2 Methods and systems for performing submucosal medical procedures
Instruments, systems and methods are provided for performing submucosal medical procedures in a desired area of the digestive tract using endoscopy. Instruments include a safe access needle injection instrument, a submucosal tunneling instrument, a submucosal dissection instrument, a mucosal resection device. Systems include a combination of one or more of such instruments with or without injectable agents. Embodiments of various methods for performing the procedures are also provided.
US08906049B2 Device for treating hardened lesions and method of use thereof
A balloon catheter is provided that may be used to dilate hardened regions of a stenosis on a vessel wall. The balloon catheter is provided with cutting elements that extend along a surface of a balloon. At least one bioactive is present, either on the cutting element, within the interior of the balloon, within the material of the balloon or on an outside surface of the balloon. The bioactive is delivered to the vessel wall upon dilation of the balloon.
US08906047B2 Mesh implant for use in reconstruction of soft tissue defects
The present invention relates to a resorbable polymeric mesh implant, that is intended to be used in the reconstruction of soft tissue defects. The mesh implant comprises at least a first and a second material, wherein the second material is substantially degraded at a later point in time than the first material following the time of implantation. The mesh implant is adapted to have a predetermined modulus of elasticity that gradually is decreased until the mesh implant is completely degraded and subsequently resorbed. Due to the gradual decrease in the modulus of elasticity of the inventive mesh implant, the regenerating tissue may gradually take over the load applied to the tissue defect area.
US08906044B2 Knot pusher device
A knot pusher device for deploying a plurality of pretied knots to a surgical site is provided. In one embodiment, the knot pusher device comprises a shaft, an inner tubular member, and an inner rod, each having a proximal end and a distal end. The inner tubular member is provided within the shaft and is radially translatable with respect to the shaft. The inner rod is provided within the inner tubular member and is slidably coupled to the inner tubular member and is axially translatable with respect thereto.
US08906043B2 Laparoscopic suturing instrument with perpendicular eccentric needle motion
A suture needle driving instrument comprises a shaft and an end effector. The end effector is located at the distal end of the shaft and includes a pair of needle grasping arms. Each grasping arm extends along a respective arm axis. The grasping arms are operable to drive a suture needle along a rotational path about an axis, such as one of the arm axes, that is offset from the central longitudinal axis of the shaft. The rotational path may be perpendicular to the axis of the shaft. A needle driven by the end effector may have an arc radius that is greater than the radius of the shaft. At least one of the needle grasping arms may include a dogleg feature positioning a distal portion of the grasping arm outside the radius of the shaft. The instrument may be used through a trocar during minimally invasive surgery.
US08906038B2 Devices and methods for laparoscopic gastric tissue reconfiguration
Devices and methods for forming and securing tissue folds and elongated invaginations in gastric tissue are used as a treatment for obesity. In several embodiments, a plurality of tissue folds is formed along the greater curvature of the stomach using laparoscopic tissue anchor deployment devices. Additional embodiments include various combinations of tissue folds, elongated invaginations, and other reconfigurations of stomach tissue using laparoscopic devices or laparoscopic devices in combination with endoscopic devices.
US08906036B2 Surgical retrieval apparatus
A surgical retrieval apparatus for receipt of multiple tissue specimens includes a collection bag, a support ring, and a flip ring. The collection bag includes first and second packets each having an outer portion and an inner portion. The first and second packets define first and second adjacent chambers, respectively, that are each configured for receipt of a tissue specimen therein. The first and second packets are coupled to both the support ring and the flip ring. The flip ring is pivotably coupled to the support ring and is rotatable relative to the support ring between a first position, wherein the first chamber is accessible for depositing a tissue specimen therein and a second position, wherein the second chamber is accessible for depositing a tissue specimen therein.
US08906035B2 Endoscopic drop off bag
A specimen retrieval device may comprise the specimen retrieval bag for retrieval biological materials, a hybrid shaft, a first collapsible arm, and a second collapsible arm. The hybrid shaft may comprise a proximal end and a distal end, wherein the distal end is flexible, and wherein the proximal end is rigid. The first collapsible arm may be located at the distal end of the hybrid shaft, and may include a first portion. The second collapsible arm may be located at the distal end of the hybrid shaft, may include a first portion and a second portion. The second portion of the second collapsible arm may extend distally beyond the first portion of the second collapsible arm. The specimen retrieval bag may have an open end and a closed end, and may be configured to be retained upon the first collapsible arm and the second collapsible arm.
US08906028B2 Bone graft delivery device and method of using the same
The present invention relates to a device and method for delivery of bone graft material to any portion of a patient which requires bone graft material. The device according to various embodiments delivers bone graft to a bone graft receiving area. The bone graft delivery device is formed such that a hollow tube and plunger selectively and controllably place bone graft material in or adjacent to the bone graft receiving area.
US08906026B2 Method and apparatus for performing an open wedge, high tibial osteotomy
An osteotomy plate for maintaining the spacing of a wedge-like opening in bone, the osteotomy plate comprising: a body having a front side and a back side; a key extending out of the back side of the body for disposition in a keyhole formed in the bone along the wedge-like opening; and a plurality of mounting holes for receiving fixation screws therein, the mounting holes being formed in the body such that when the key is disposed in the keyhole, the mounting holes direct the fixation screws into bone on either side of the wedge-like opening.
US08906025B2 Surgical instrument for impacting and extracting a shaping instrument and a shaping instrument useable therewith
A surgical instrument including a shaping instrument for shaping a bone as well as an impaction/extraction device for use with the shaping instrument is disclosed.
US08906020B2 Dynamic external fixator and methods for use
An external fixation system has a planar ring with an adjustable device having a body releasably mounted on the ring. The adjustable device includes a first member for movement in a direction generally perpendicular to the ring. A second member is mounted on the first member for movement in a direction parallel to a side wall of the planar ring. A method for treating a broken bone includes providing an external fixation system and inserting a first k-wire or half pin through a first piece of the bone and affixing the first k-wire or half pin to the ring, then inserting a second k-wire or half pin through a second piece of bone and affixing the second k-wire or half pin to the adjustable device. The pieces of bone are realigned, compressed, or distracted by adjusting at least one of the first and second adjustable members.
US08906013B2 Control handle for a contact force ablation catheter
A control handle for a steerable catheter body for navigation of the catheter body through a biological lumen and manipulation at a treatment site. The control handle includes a housing assembly that houses a piston assembly and a resistance adjusting assembly. The resistance adjusting assembly can be adjusted to provide the desired frictional characteristics of the user for control of the resistance between the piston assembly and the housing assembly. In one embodiment, the piston assembly is configured to provide a frictional resistance that varies dynamically to substantially match the restorative force across the range of catheter tip deflection. Other embodiments include a vibrating member that provides tactile feedback to the operator to indicate conditions at the distal end of the catheter, such as contact force.
US08906011B2 Medical device for use in bodily lumens, for example an atrium
A device positionable in a cavity of a bodily organ (e.g., a heart) may discriminate between fluid (e.g., blood) and non-fluid tissue (e.g., wall of heart) to provide information or a mapping indicative of a position and/or orientation of the device in the cavity. Discrimination may be based on flow, or some other characteristic, for example electrical permittivity or force. The device may selectively ablate portions of the non-fluid tissue based on the information or mapping. The device may detect characteristics (e.g., electrical potentials) indicative of whether ablation was successful. The device may include a plurality of transducers, intravascularly guided in an unexpanded configuration and positioned proximate the non-fluid tissue in an expanded configuration. Expansion mechanism may include helical member(s) or inflatable member(s).
US08906007B2 Electrosurgical devices, directional reflector assemblies coupleable thereto, and electrosurgical systems including same
A directional reflector assembly includes a tubular shaft having a proximal end and a distal end and adapted to operably engage an electrosurgical ablation probe, and a conical aperture having a proximal open apex joined to a distal end of the tubular shaft, and a distal open base, wherein an interior volume of the tubular shaft is open to the conical aperture.
US08905989B2 Tampon with segmented grooves
An intravaginal tampon is formed of compressed material and has an outer surface, an insertion end, a withdrawal end, and a center portion formed between the insertion and withdrawal ends. The outer surface has at least two segmented grooves are formed therein, and each segmented groove is separated from and spaced at a distance from an adjacent segmented groove. Each segmented groove has at least one substantially longitudinal segment and at least one accumulator segment. The arrangement of the segments provides a pooling region to impede bodily fluid flow along the outer surface of the tampon.
US08905985B2 Systems and methods for controlling operation of a reduced pressure therapy system
Negative pressure wound therapy apparatuses and dressings, and systems and methods for operating such apparatuses for use with dressings are disclosed. In some embodiments, controlling the delivery of therapy can be based on monitoring and detecting various operating conditions. An apparatus can have a controller configured to monitor the duty cycle of a source of negative pressure and, based on the monitored duty cycle, determine whether a leak is present. The controller can be configured to provide an indication that a leak is present. For example, the controller can be configured to suspend and/or pause the delivery of therapy, and to restart the delivery of therapy due to a timeout, request from a user, etc. In addition, the controller can be configured to pause and/or restart the delivery of therapy upon a request from the user, such as in response to the user operating a switch.
US08905982B2 Gas mist pressure bath system
The invention is to provide a gas mist pressure bath system, which is possible to control the amount of gas and liquid, pressure and others, and cause a gas mist to be absorbed through a skin and mucous membrane of a human living body under an optimum condition. The present system comprises a gas supply means 11, a liquid supply means 21, a gas mist supply means 31 for generating and supplying the gas mist by storing the liquid inside thereof and while injecting a gas into the stored liquid, concurrently applying supersonic vibration to this liquid, and a living-body cover member 41 for covering the skin and mucous membrane of the living body and sealing inside the gas mist supplied from the gas mist supply means, and the gas mist supply means 31 comprises a supersonic vibrator 33, and a storage 32 having the gas mist generating tank 321 and a supersonic transmission tank 322, and the gas mist within the living-body cover member is caused to contact the skin and mucous membrane of the living body at pressure of not less than a predetermined value.
US08905981B2 Pump with integrated control unit
A pump for use in anal irrigation includes a control unit integrated in the pump. The control unit includes a cylindrical housing element and a valve element fitted in the housing. The valve element and the housing element are adapted for rotating with respect to each other between a position allowing the pump to pump air into a balloon, a position allowing the pump to pump air into a reservoir bag and an evacuation position. The control unit is actuated by a handle attached to the rotatable valve element. The handle extends radially out from the rotatable valve element and the cylindrical housing.
US08905979B2 Method of administration of a pulmonary surfactant
The present invention concerns a method for treating a respiratory distress in a infant in need of such treatment, the method comprising intratracheal administration of a pulmonary surfactant by a thin tube.The invention also concerns a kit for performing said method.
US08905977B2 Surgical stapling instrument having an electroactive polymer actuated medical substance dispenser
A surgical stapling and severing instrument enables minimally invasive surgical procedures by having upper and lower jaws (i.e., anvil and staple channel) that are positioned with an elongate shaft and handle through a surgical opening, and in particular through a cannula of a trocar. A pair of fluid bladders (lift bags) are positioned in the staple channel beneath a proximally projecting lever tray so that transfer of fluid from the handle causes closing and clamping of the anvil. The bi-directional fluid control may be mechanically produced at the handle or by activating an electroactive polymer actuator. Once firing is sensed, an EAP plunger in a medical substance syringe inserted into the elongate shaft is activated to dispense a medical substance (e.g., anesthetics, adhesives, cauterizing substances, antibiotics, etc.) and is guided along a firing bar to a cutting surface of an E-beam placing the substance on tissue as severed.
US08905975B2 Container, device and method to store and expel a product
The present invention relates to a container comprising: a body; a pusher movable with respect to the body between an initial position and an end-of-use position; a locker located on the pusher and forming an abutment so as to be able to abut against the body between the initial position and the end-of-use position, wherein, the abutment abuts against the body to limit distal movement of the pusher relative to the body to a pusher locking position located between the initial position and the end-of-use position; a locking arrangement capable of, temporarily, locking the locker on the pusher so as to define a locker locking position of the locker on the pusher, the locker locking position establishing the position of the abutment relative to the pusher so as to set the pusher locking position; and, an unlocking arrangement designed so that, with triggering, the locking arrangement is released so as to allow the locker to be displaced relative to the pusher and for the pusher to be moved past the pusher locking position toward the end-of-use position.
US08905973B2 Hemostasis valve with roller seal
A hemostasis valve has a housing having proximal and distal ends defining proximal and distal openings configured for passage of a medical device therethrough. The housing further defines a cavity between the proximal and distal ends. One or more rollers are received within the cavity and define end sections and a central section having a smaller diameter than the end sections. Sleeves are disposed about the rollers and are elastically deformable to form a fluid seal around the device. The sleeves each assume a first form when the device is absent from the cavity wherein a radially inner surface of the sleeve is located at a first distance from the central section of a roller and a second form when the device is present in the cavity wherein the surface is located at a second distance, less than the first distance, from the central section of the roller.
US08905972B2 Infusion pumps
Ambulatory infusion pumps, pump assemblies, and baseplate assemblies, including cartridges, baseplates, cannulas, inserters, and related components and batteries therefor, as well as component combinations and related methods.
US08905964B2 Drug storage and dispensing devices and systems comprising the same
Drug storage and dispensing devices for dispensing a drug dosage form to a patient are disclosed. A cartridge includes a cartridge housing and a pusher. The cartridge housing defines a channel within which multiple tablets are disposed. The cartridge housing is configured to be removably coupled to a tablet dispensing device. A first portion of the pusher is disposed outside of the channel. A second portion of the pusher is movably disposed within the channel, and is configured to exert a force on the plurality of tablets to convey a first tablet from the channel into the tablet delivery device when the force is exerted on the first portion of the pusher.
US08905954B2 Systems and methods for providing a channel through an orthopedic cast
An appliance which removably stores a portion of a catheter and an adapter, where the indwelling portion of catheter is still inside the body tissue of a patient. The appliance has an aperture that permits connection of a vacuum source such as hospital suction. When the appliance containing the catheter is held against the portion of the body including the indwelling site of the catheter, the vacuum source is applied, having a tendency to hold the appliance in place against the body. An orthopedic cast can be fabricated around the appliance, after which time the vacuum can be deactivated and the appliance can be removed, revealing a channel formed in the orthopedic cast. Through the channel, the distal portion of the catheter and the adapter can be accessed, facilitating continued post-operative anesthesia, easy visual inspection for signs of infection or dislodgment of the catheter and permitting easy removal when needed.
US08905952B2 Simple portable lumbar spine distraction device and method
A simple, lightweight, portable, lumbar spinal distraction device is provided which employs a frame having concave left and right hand upper leg contacting members for asserting forces against substantially vertically oriented left and right upper leg portions of a user assuming a substantially horizontal position. The user pushes the portable frame forward by manually grasping a pair of handles, causing the left and right contacting members to press against the vertically oriented left and right upper leg portions respectively. Increased unilateral traction ability is produced by simply having the user apply extra force to one handle or the other. This will permit users suffering from unilateral pain in the buttocks, hip or leg to obtain a little extra pressure on the symptomatic side. Anyone who has suffered low back pain can relate to the fact that some days the pain feels more right sided and some days more left sided.
US08905951B2 Motorized functional electrical stimulation step and stand trainer
A functional electrical stimulation step and stand system comprising two footplates (left and right) connected to a primary drive motor that cause the footplates to move in a reciprocal motion. The footplates are further connected to corresponding servos, which allow for control of the movement of the footplate with respect to an axis. system comprises an electrical stimulation control unit. The stimulation step and stand system further comprises a control unit that has electrical stimulation leads connected to electrodes that deliver an electrical impulse to a patient's muscles. In a further embodiment, the control unit has one or more wireless stimulators.
US08905944B2 Protective cover assembly for a needle assembly
In one embodiment, the protective cover assembly has a hub that is to be mounted on a needle assembly, such as a biopsy needle assembly, a cap that is movable off the hub to move over a cannula or stylet of the needle assembly and a pair of rolls of film within the cap. The rolls of film are secured at one end to the hub to unwind over the cannula. Pressing rolls or springs press the longitudinal edges of the film strips together in sealed relation to encase the cannula while the cap receives the end of the cannula or stylet in sealed relation. In a second embodiment, the cap is integrated with a hub of a needle assembly having a cannula extending from the hub.
US08905942B2 Apparatus and method for outputting heart sounds
An apparatus for outputting heart sounds includes an implantable system and an external system. The implantable system includes a sensor for generating sensed signals representing detected heart sounds, an interface circuit and a control circuit for receiving the sensed signals, generating data representing the heart sounds therefrom, and transmitting the data to the external system via the interface circuit. The external system includes an interface circuit for communicating with the implantable system, and a control circuit for receiving the data representing the heart sounds and for generating control signals that cause an output device to generate outputs representing the sounds. The implantable system may also include a sensor(s) for detecting cardiac electrical signals. In this case, outputs representing the cardiac electrical signals are also output.
US08905939B2 Method and apparatus for continuous assessment of a cardiovascular parameter using the arterial pulse pressure propagation time and waveform
A method and apparatus for determining a cardiovascular parameter including receiving an input signal corresponding to an arterial blood pressure measurement over an interval that covers at least one cardiac cycle, determining a propagation time of the input signal, determining at least one statistical moment of the input signal, and determining an estimate of the cardiovascular parameter using the propagation time and the at least one statistical moment.
US08905937B2 Methods and apparatus for locating a surface of a body lumen
An embodiment of an apparatus for locating a surface of a body lumen is disclosed. The apparatus includes a locator assembly that has a distal end region configured to extend into an opening of the body lumen and to selectably engage at least a portion of the body lumen adjacent to the opening. The distal end region includes at least one surface engaging element that is configured to engage the surface of the body lumen. The apparatus includes a measuring device that is in electrical communication with the surface engaging element. The measuring device is configured to determine changes in measurable characteristics of the surface engaging element. Methods and apparatus for locating a surface of a body lumen are also disclosed.
US08905933B2 Ultrasonic diagnostic apparatus
An ultrasonic diagnostic apparatus capable of quantitatively obtaining a blood flow velocity unaffected by angle dependence. The apparatus includes: an ultrasonic probe including ultrasonic transducers for receiving ultrasonic echoes to output reception signals; a first movement information calculating unit for calculating first movement information on movement of a mobile element in a sound ray direction within the object based on the reception signals; a signal calculating unit for calculating azimuth direction component signals representing components of ultrasonic echoes in an azimuth direction based on the reception signals; a second movement information calculating unit for calculating second movement information on movement of the mobile element in the azimuth direction within the object based on the azimuth direction component signals; and a two-dimensional velocity calculating unit for calculating two-dimensional velocity information of the mobile element moving within the object based on the first and second movement information.
US08905927B2 System and method for non-intrusive health monitoring in the home
A hand-held device, such as a remote control, is provided for operation of a consumer appliance and is equipped with one or more biometric sensors to capture and report on the health condition of a user of the hand-held device. The data captured by such a hand-held device may be evaluated locally in the hand-held device itself or may be conveyed to a target consumer appliance either for local evaluation by that consumer appliance or for onward transmission to a central off-site monitoring service.
US08905923B2 Surgical retractor for wrist procedures
A surgical retractor configured for use in surgical procedures to repair patient wrist distal radius bone fractures. The retractor includes an elongated handle portion, a wing portion coupled to the handle portion, and a hook portion at a working end of the retractor. The hook portion is configured to engage the radius bone of a surgical patient during a procedure. The wing portion is positioned intermediate the hook portion and the elongated handle portion and configured with a sufficient width to retract the patient's pronator quadratus muscle, while having a height such that the wing portion does not contact the median nerve of the surgical patient. A portion of the retractor above the wing portion is configured to contact the median nerve while being sufficiently narrow so as not put excessive pressure on the median nerve to cause nerve damage.
US08905922B2 Devices, systems and methods for diagnosing and treating sinusitis and other disorders of the ears, nose and/or throat
Sinusitis, enlarged nasal turbinates, tumors, infections, hearing disorders, allergic conditions, facial fractures and other disorders of the ear, nose and throat are diagnosed and/or treated using minimally invasive approaches and, in many cases, flexible catheters as opposed to instruments having rigid shafts. Various diagnostic procedures and devices are used to perform imaging studies, mucus flow studies, air/gas flow studies, anatomic dimension studies, endoscopic studies and transillumination studies. Access and occluder devices may be used to establish fluid tight seals in the anterior or posterior nasal cavities/nasopharynx and to facilitate insertion of working devices (e.g., scopes, guidewires, catheters, tissue cutting or remodeling devices, electrosurgical devices, energy emitting devices, devices for injecting diagnostic or therapeutic agents, devices for implanting devices such as stents, substance eluting devices, substance delivery implants, etc.
US08905919B2 Endoscope
An endoscope includes a distal rigid portion, a bending portion comprising a first bending portion and a second bending portion and a flexible tube portion. The endoscope further includes an operation wire, a wire guide member, a bending operation portion. The endoscope further includes a regulation wire, the regulation wire being longer than the bending portion, the regulation wire being inserted through the first bending portion and the second bending portion, the regulation wire being provided to face the operation wire in the diametrical direction of the bending portion, the regulation wire regulating the bending of the bending portion so that the second bending portion is bent in a direction opposite to the bending direction of the first bending portion and the bending portion is bent in an S-shape when the first bending portion is bent.
US08905917B2 Penis extender
A system for extending a penis. The system includes a woven cylinder. The woven cylinder includes a set of fibers woven into a cylindrical shape. The woven cylinder is configured to lengthen when a force is applied to the woven cylinder and decrease in circumference when the woven cylinder lengthens. The woven cylinder is further configured to be placed on the penis of a user, applying a lateral force to the penis.
US08905915B2 Self-regulating gastric band with pressure data processing
A self-regulating gastric band apparatus for adjusting stoma size is disclosed. The apparatus includes an adjustable gastric band that has an expandable portion containing a volume of fluid. A band adjustment assembly is provided for implanting with the gastric band that includes a sensor for sensing fluid pressure in the expandable portion. The band adjustment assembly further includes a pump assembly connected to the expandable portion and to a controller that operates the pump assembly to adjust the volume of the fluid in the band based on the sensed fluid pressure. The band adjustment assembly includes memory storing an operating range relative to a target fluid pressure, and the pump assembly is operated to maintain the sensed band pressure within the operating range. The target pressure is set to maintain pressure variations below a predefined variation limit generally corresponding with satiated fill volumes for a particular patient and implanted band.
US08905907B2 Cutting device for cutting lenses
A cutting device includes a support base, a first slide module, a second slide module slidably connected to the first slide module, and a cutting module. The support base includes a support surface and a slide portion on the support surface. The first slide module is slidably positioned on the slide portion. The sliding direction of the second slide module is perpendicular to the sliding direction of the first slide module. The cutting module includes a fixed frame fixed on the second slide module, a driving device fixed on the fixed frame, and a cutter connected to the driving device. The driving device drives the cutter to rotate around a central axis of the cutter and move up and down along the central axis. The central axis is perpendicular to the support surface. The cutter includes a hollow cylindrical blade. An end surface of the blade faces the support surface.
US08905905B2 Pushup exerciser having multiple hand positioning
A pushup exerciser includes a supporting board formed of a pair of joined board sections each defining an upper surface having a plurality of post receptacles formed therein. The post receptacles are arranged in pairs with each pair suitably spaced for receiving attachment posts of a handle unit. Each post receptacle pair includes a color indicia. The color indicia are selectively colored to provide association between handle unit positions in accordance with a selected theme such as muscle group emphasis. A pair of handle units suitable for gripping during pushup exercise are locatable and attachable to the board surface at positions and angular orientations defined by the post receptacle pairs.
US08905903B2 Pulling rope fixing structure
A pulling rope fixing structure includes a handle, a grip rope, a fixing device, an elastic element and a pulling rope. The handle is a hollow tubular body with the grip rope passed through the handle; the grip rope has first and second ends with first and second openings respectively; the fixing device includes a retaining ring and a fastening element, and the fastening element has a hollow sleeve passed into the first and second openings and operated with the retaining ring to fix the grip rope. The elastic element is installed in the hollow sleeve and has a penetrating hole for passing the pulling rope and separating the pulling rope from the fixing device. The pulling rope not in a direct contact with the metal fixing device will not be worn directly during exercises, and the service life of the pulling rope can be extended effectively.
US08905902B2 Exercise kit
A kit for performing exercises. The kit includes a back board, a standing board and a bench press bar. The kit also includes a plurality of bungee cords that are of different strengths and which can be attached to the various elements of the kit to establish a precise resistance to accommodate a particular user for a particular exercise.
US08905897B2 Creep torque control method of vehicle
Disclosed is a method and power delivery system for controlling creep torque in a hybrid or electric vehicle. More specifically, a brake signal is detected and a creep torque output is controlled based on the brake signal. The creep torque is outputted for a predetermined time from a point when a brake on signal is first generated. Accordingly, a creep torque is generated for a predetermined time when a brake is being operated and backlash is eliminated between gears so as to prevent a backlash shock from the gears when the brake is released. Additionally, the vehicle may be propelled forward or backward by the creep torque in the creep torque control method of a vehicle according to an exemplary embodiment of the present invention.
US08905889B2 Planetary gear train of automatic transmission for vehicle
A planetary gear train of an automatic transmission may include: a first shaft receiving engine torque; a second parallel shaft; a first planetary gear set on the first shaft including a first element engaging the first shaft and a transmission housing, a second element engaging the first shaft and the transmission housing, and a third output element; a second planetary gear set on the second shaft, and including a fourth element engaging the first element, a fifth element connected to the third element and directly connected to an output gear, and a sixth element connected to the first shaft and engaging the first element; three transfer gears; and frictional elements including four clutches connecting the first and second elements to the first shaft and connecting the first element to the fourth and sixth elements, and two brakes connecting the first and second elements to the transmission housing.
US08905887B2 Unison ring gear assembly
Disclosed is a unison ring assembly. The assembly comprises a first unison ring and a second unison ring concentrically aligned along a principal axis, the first and second unison rings being rotatable about the principal axis. The assembly further comprises a gear mechanism configured to simultaneously rotate the first and second unison rings about the principal axis.
US08905886B2 Gear device
Disclosed is a gear device which comprises an outer cylinder fixable to one of two counterpart member; a crankshaft; a carrier configured to be fixable to the other counterpart member and formed with a through-hole, wherein the carrier is adapted to be relatively rotated with respect to the outer cylinder in interlocking relation with rotation of the crankshaft; and a cylindrical body disposed in the through-hole of the carrier. The through-hole of the carrier has an inner peripheral surface formed with an outward groove. The cylindrical body has an outer peripheral surface formed with an inward groove in opposed relation to the outward groove of the carrier. The gear device is provided with an O-ring disposed to extend from an inside of the outward groove to an inside of the inward groove.
US08905885B2 Vehicle drive device
A vehicle drive device configured with reduced axial dimensions, while still having appropriate lubrication. The vehicle drive device is configured with an input shaft coupled to an engine, a rotary electric machine, and an output shaft coupled to wheels. A power transfer mechanism couples input shaft, the rotary electric machine, and the output shaft. A case houses at least the rotary electric machine and the power transfer mechanism. An oil reserving portion capable of reserving oil supplied by rotation of the power transfer mechanism is provided above the rotor shaft inside the case. A communication oil passage is oriented between the oil reserving portion and an inner circumferential space formed inside the rotor shaft. The rotor shaft is disposed to be inserted into the inside housing space, and has a supply communication hole that communicates between the inner circumferential space and the inside housing space.
US08905878B2 Bicycle sprocket assembly
A bicycle sprocket assembly is provided with at least a first sprocket and a first axial spacer. The first sprocket includes a first sprocket mounting portion, a plurality of first sprocket arms extending radially from the first sprocket mounting portion and a first chain engaging portion disposed on radial outer ends of the first sprocket arms. The first chain engaging portion includes a plurality of first teeth. The first axial spacer is disposed on a first sprocket side surface of the first sprocket. The first axial spacer has a first spacer mounting portion and a plurality of first spacer arms extending radially from the first spacer mounting portion. The first spacer arms are partially visible from an axial view of a second sprocket side surface that faces in an opposite direction from the first sprocket side surface.
US08905876B2 Game ball cover with improved stripes
An American football is configured for direct contact with a user's hands and includes first and second transversely extending stripes and a plurality of cover panels. The cover panels have an outer surface formed of a first material. One of the cover panels is formed of first, second and third sub-panels. One of the side edges of the first and second stripes is fixedly coupled to one of the first and second sub-panels, respectively, and the other of the side edges of the first and second stripes is fixedly coupled to one of the second and third sub-panels, respectively. The stripes having an outer surface formed of a second material. The second material has a static coefficient of friction that is greater than the static coefficient of friction of the first material when measured in accordance with the standard test method for static coefficient of friction of ASTM D1894-01.
US08905875B1 Arrow system
An arrow system for reducing a kill time of a prey features an arrow shaft and an arrowhead. An arrowhead first end features a terminating point for piercing and an arrowhead second end features an arrowhead threaded rod for attaching to a shaft first end. The system features a tail component having a tail second end with a nock for interfacing with a bow string. A tail first end features a tail threaded rod for attaching to a shaft second end. A plurality of fletchings, each having a sharp edge, is located on an outer periphery of the tail component. Each fletching features a centrally located aperture. Each fletching outer periphery features a shape of a scalene triangle. Each fletching aperture features a shape of a similar triangle with respect to the scalene-triangle-shaped fletching outer periphery.
US08905873B2 Hockey stick shaft protector
A protective strip device to apply to the shaft of a hockey stick, the strip device having an inner side face, adhesive on the inner side face for bonding to the shaft of the stick, an outer facing side defining a central groove, and two spaced apart shock absorbing side abutment ridges extending lengthwise along opposite sides of the central groove, and a plurality of spaced apart openings formed along the central groove.
US08905872B2 Sporting goal transport system
A sport goal movement system that includes drive and control systems. The drive system preferably includes a motor that selectively drives one of a wheel or a track. The drive system can be integrated with and/or permanently or removably secured to the sport goal assembly. Operation of the drive system effectuates single user unassisted and possibly remote translation of the sport goal assembly relative to a ground surface.
US08905865B2 Golf ball
A golf ball includes a core, a cover covering the core, and a clear layer covering the cover. The cover has dimples and a land. An xy coordinate of a hue of an outermost layer in the core excluding a colorless and transparent layer is included in any one of eight zones I to VIII. An xy coordinate of a hue of the cover is included in any one of the eight zones I to VIII which is different from and is not adjacent to the zone in which the xy coordinate of the hue of the outermost layer is included. A ratio (T1/T2) of a thickness T1 of the cover immediately below a deepest portion of each dimple and a thickness T2 of the cover immediately below the land is equal to or greater than 0.50 but equal to or less than 0.80.
US08905862B2 Golf balls containing layers based on polyamide and fatty acid salt blends
Multi-piece golf balls having a solid core of at least one layer and cover of at least one layer are provided. At least one of the layers is formed from a thermoplastic polyamide composition, consisting essentially of a blend of about 40 to about 99% by weight polyamide and about 1 to about 60% by weight fatty acid salt. Preferably, the ball has a dual core construction. A rubber composition is preferably used to form the inner core and the polyamide composition is preferably used to form the outer core layer. The resulting ball has high resiliency along with a soft feel.
US08905857B1 Golf putter with adjustable head
A putter for use in a game of golf including a handle from which exends a shaft having a lower extension portion connected to a hosel mounted on a putter head having a front putting face, upper and lower surfaces and opposite side portions and wherein a central alignment groove extends along a central longitudinal axis of the head toward the putting face and wherein pairs of alignment members extend parallel on opposite sides of the central alignment groove and perpendicular to the putting face, and wherein at least one projection from the hosel is spaced above one of the pairs of alignment members and includes an alignment band for aligning with the one of pair of alignment members when the putter is addressed relative to a ball.
US08905856B2 Method and apparatus for determining a relative orientation of points on a rigid body
An inertial measurement unit is affixed to a rigid body. The inertial measurement includes a gyroscope that measures a first angular velocity and an angular acceleration; a first accelerometer that measures a first acceleration; a communications unit that receives a measurement signal, the measurement signal including a second acceleration transmitted from a second accelerometer, the second accelerometer being affixed to the rigid body; and a controller that calculates a relative orientation of the inertial measurement unit and the second accelerometer, and a distance separating the inertial measurement unit and the second accelerometer.
US08905854B2 Reaction component for linear induction motor
A reaction component or plate for a linear induction motor incorporates a flexibility increasing feature and a wear resistant feature.
US08905853B2 System and method for a portable ice skating rink
A portable ice skating rink comprising, a flexible rubber sheet having a first end and a second end wherein the first end is connected to the second end thereby forming a sidewall, wherein the sidewall is positioned on a horizontal surface to form the border of a closed geometric shape thereby defining a skating surface area, and a flexible, water-proof slip draped over and connected to the sidewalls, thereby forming a liner of a structure capable of containing a liquid inward of the sidewalls to create a skating surface.
US08905849B1 Updating virtual trading cards
According to particular embodiments, virtual trading cards including virtual statistics or characteristics of a virtual, game-based representation of a real-world sports player or other character, are updated periodically to reflect changes in a player's real-world performance. Adjusting the virtual characteristics using real-world performance causes the characteristics of the sports player's virtual trading card to change in a virtual environment as does a corresponding player's video game performance. Characteristics of team members are variable based on characteristics of other team members and opposing team members or other competition factors.
US08905843B2 Image integration, mapping and linking system and methodology
An adapter interface apparatus has a user input device and an associated video display. The user selects a distinguishable visual image representation for association into an audiovisual presentation, such as where that user is identified. For example, color, size graphics or shape can be used to distinguish users. In one embodiment a digitized image of each user's face is used as the distinguishable representation. Alternatively, the user can create an original image or select one of a predetermined set of visual images as the user's identification for use in the audiovisual presentation. In one embodiment, the adapter interface is coupled to an audiovisual presentation system and a storage card containing User Images. The adapter interface system integrates a selected User Image from the Storage Card into the audiovisual presentation.
US08905838B2 Detecting game play-style convergence and changing games
Gaming technologies for detecting convergence in game play and then changing a game to overcome or inhibit convergence are generally described. In one example, a representative gaming method can include: providing a game simultaneously to a plurality of computing devices; identifying a game scenario type that includes game tests provided to the computing devices; obtaining game actions from the computing devices in response to the game tests; determining a convergence of the game actions across the computing devices that pass the game tests; and changing the game tests of the game scenario type such that the game actions of the convergence fail the changed game tests. The game can be a MMORPG, the game scenario can be a battle; the game tests can be opponents; the game actions can be battle actions; and convergence can be repeated game action patterns that defeat opponents in the battles.
US08905837B2 Video slot gaming machine
A gaming machine and method are provided which provide a video slot game to a player. The video slot game includes a plurality of cells arranged in a grid. The grid has a plurality of rows and columns. The machine and method display a base instance of the video slot game and in response to occurrence of a triggering event, the base instance of the video slot game is split and a plurality of sub-instances of the video slot game are displayed.
US08905835B2 Method, system, and program product for conducting multiple concurrent bingo games
A method for conducting bingo games includes using a server to collect game play requests from a plurality of electronic player stations. The server determines if a group of the collected game play requests meets one or more predefined conditions for establishing a quorum, and if so conducts a game with the group of game play requests. Even after the game is started, the server continues to collect game play requests in preparation for conducting additional games. When enough game play requests are collected, the server starts the next game, even if previous games are still in progress.
US08905834B2 Transparent card display
Interactive gaming tables are provided that include one or more video displays. The interactive gaming tables are operable to detect and distinguish between various types of physical objects placed on the interactive gaming table, associate a function with at least one type of physical object and generate a video display window on a video display that is viewable through a transparent portion of the one type of physical object. Video images including content associated with the function can be provided in the video display window. The interactive gaming tables can be used to provide a wager-based table game where the function associated with one of the physical objects can be a function related to play of the wager-based table game or a function related to a particular player playing the wager-based game. A mostly transparent, credit-card sized object designed to be carried by a game player is one example of one type of physical object that can be utilized with the interactive gaming table.
US08905833B2 Gaming system and method for providing a matching symbols game
In various embodiments, the gaming system enables a player to select one or more playing cards from a plurality of playing cards, wherein different playing cards include or are otherwise associated with one or more different symbols. The gaming system then determines if any matches occur amongst the plurality of symbols of a plurality of playing cards (including at least the player's selected playing card(s)). Following such a determination, the gaming system determines and provides zero, one or more awards based on one or more of: (i) which, if any, matching symbols occurred amongst the plurality of symbols of the plurality of playing cards, and (ii) a quantity of symbol matches which occurred amongst the plurality of symbols of the plurality of playing cards.
US08905825B2 Container for storing knifes, utensils, and the like having integral blade sharpener
A container for storing at least one object, such as a knife, utensil, and the like, wherein the object has a blade that is occasionally dressed is disclosed. The container includes a housing presenting an object-receiving opening and a blade-dressing assembly configured to provide selective dressing of the blade. The blade-dressing assembly includes a carrier and a dressing component supported on the carrier. The carrier is shiftably supported on the housing so as to move between a storage position in which the dressing surface is incapable of engaging the blade and an operating position in which the dressing surface is engageable by the blade.
US08905822B2 Clamp nut
A flange nut for use in mounting a power tool component onto a rotatable spindle of a power tool. The flange nut includes one or more non-circular apertures into which an end of a shaped tool such as an Allen wrench may be inserted. Torquing or otherwise applying a force to a portion of the shaped tool serves to thread the nut along the spindle either towards the power tool component to secure the power tool component on the spindle or away from the power tool component to allow for removal of the power tool component.
US08905820B2 Scraper and sandblaster assembly and methods of use
A scraper and sandblaster assembly is presented including a sandblaster having at least a debris collection cover and a granular particle container for holding granular particles and a scraper configured to operate with the sandblaster, wherein the granular particle container includes a plurality of separate and distinct chambers, each chamber including a different granular particle. The sandblaster includes at least one actuation mechanism for selectively or collectively dispensing the different granular particles.
US08905818B2 Process for the manufacture of stone blocks
This invention relates to a process which may be automated for the manufacture of stone blocks for use as finished landscape stone blocks from quarry stone. The natural stone is quarried from the quarry and split into rectangular blocks, with squared ends and the top and bottom surfaces are ground with a plurality of grooves and ridges of varying heights. The ridges of varying heights are then removed thereby producing a surface having ridges of uniform height and grooves of uniform depth. The blocks may be used to form an architectural wall. The process is also applicable to pavers, steps and coping stones.
US08905816B2 Blast machine system controller
A system for system for controlling functions of a multi-feed blasting apparatus is disclosed. Tank pressure, charge/discharge control, status of a vessel cover, total hours of pressurization or operation for the vessel and individual feed lines, ambient environmental or weather conditions, and abrasive material level inside the vessel may also be monitored and controlled by the disclosed system.
US08905815B2 Racing vehicle game
A method and apparatus for controlling the position of a vehicle on a track so as to provide a slotless racing vehicle game is described. The method involves measuring the lateral position of the vehicle on the track so as to minimize the distance with a user defined lateral position. A measured velocity of the vehicle is then feedback to a steering servo in order to stabilize the vehicle's position at the desired lateral position. In particular, the gain of a controller that generates the input signal for the steering servo is varied with the reciprocal of the square of the speed of the vehicle.
US08905810B2 Plush writing toy
A plush writing toy that is attached to the user's wrist and holds a writing utensil in its front paws, legs, or hands, thereby simulating the movements of the user as the user draws, writes, colors, or paints. The plush writing toy can be manufactured to resemble an animal or any other fictional or non-fictional child's character.
US08905809B2 System and method for directing smoke in a model train system
A system and method is provided for directing smoke in a model train. In one embodiment of the present invention, the model train includes a smoke chamber physically connected to a smoke unit. The smoke unit functions to produce smoke, which is then provided to at least one smoke chamber. Each smoke chamber includes at least one exhaust opening and a valve for selectively moving smoke out of the exhaust opening(s). For example, the smoke chamber may include an intake opening, at least two exhaust openings, a piston core and a piston driven by a drive rod. By moving the drive rod, the piston can be moved through the piston core, resulting in the movement of smoke out of the exhaust openings. By positioning the exhaust openings near the wheels of the model train, the smoke system can be used to simulate steam escaping from valves or cylinders.
US08905805B2 Method of manufacturing near-field light generating element and near-field light generating element
A U-shaped groove and a V-shaped groove are formed onto a cladding disposed on a substrate, a core and a metal structure are formed inside the grooves, respectively, and then the substrate surface is planarized. Further, after a cladding is formed again, the substrate is cut and the cut surface is polished such that the metal structure inside the V-shaped groove has a predetermined thickness, thereby forming a scattering body.