Document Document Title
US08866315B2 Underwater electricity generation module provided with a base
The invention relates to an underwater electricity generation module provided with a base. The electricity generation module is of the type that comprises an elongate cylindrical casing (12) incorporating an electricity generation unit (25a, 25b) comprising a nuclear boiler (28, 29) associated with electricity generation means (30, 31) connected to an external electricity distribution post (7) by means of electric cables (6). The lower portion of the casing (12) is provided with a base (14) that rests on the bed of the water body and anchoring means (15) for anchoring the module (1) to the bed. The invention is characterised in that the base (14) is essentially in the form of a sledge which extends from one end of the casing (12) to the other and the ends (50, 51) of which are curved in the form of a spatula at each end of the casing (12), said base including zones for absorbing variations in the length of the casing (12), linked to the variation in the pressure applied thereto when submerged or surfaced.
US08866310B2 Semiconductor device
A semiconductor device is provided, which comprises a first semiconductor package, a second semiconductor package, and a connection structure. The first semiconductor package includes a first substrate. The first substrate includes a first region and a second region. The second semiconductor package is mounted on the first semiconductor package. The connection structure electrically connects the second semiconductor package and the first semiconductor package. The connection structure comprises first connection patterns at the first region. The first connection patterns provide a data signal at the first region. The connection structure further comprises second connection patterns at the second region. The second connection patterns provide a control/address signal at the second region. A number of the second connection patterns is less than a number of the first connection patterns.
US08866309B2 Chip package structure
A first back surface of a first chip faces toward a carrier. A first active surface of the first chip has first pads and a first insulting layer thereon. A second chip is disposed on the first chip and electrically connected to the carrier. A second active surface of the second chip faces toward the first active surface. The second active surface has second pads and a second insulting layer thereon. Bumps connect the first and second pads. First and second daisy chain circuits are respectively disposed on the first and second insulting layers. Hetero thermoelectric device pairs are disposed between the first and second chips and connected in series by the first and second daisy chain circuits, and constitute a circuit with an external device. First and second heat sinks are respectively disposed on a second surface of the carrier and a second back surface of the second chip.
US08866305B2 Methods of forming bonded semiconductor structures
Methods of forming bonded semiconductor structures include temporarily, directly bonding together semiconductor structures, thinning at least one of the semiconductor structures, and subsequently permanently bonding the thinned semiconductor structure to another semiconductor structure. The temporary, direct bond may be established without the use of an adhesive. Bonded semiconductor structures are fabricated in accordance with such methods.
US08866303B2 Semiconductor device with configurable through-silicon vias
Disclosed is a semiconductor device that comprises a plurality of through-silicon vias (TSVs), a signal line and a selective connector for causing the signal line to be either electrically connected to one of the TSVs or electrically isolated from all of the TSVs, based on a control signal.
US08866297B2 Air-gap formation in interconnect structures
A structure includes a substrate, and a first metal line and a second metal line over the substrate, with a space therebetween. A first air gap is on a sidewall of the first metal line and in the space, wherein an edge of the first metal line is exposed to the first air gap. A second air gap is on a sidewall of the second metal line and in the space, wherein an edge of the second metal line is exposed to the second air gap. A dielectric material is disposed in the space and between the first and the second air gaps.
US08866295B2 Semiconductor memory modules and methods of fabricating the same
The inventive concept provides semiconductor memory modules and methods of fabricating the same. The semiconductor memory module may include a module board having a first surface and a second surface opposite to the first surface, and memory chips mounted directly on the module board by a flip-chip bonding method. Each of the memory chips may include a passivation layer disposed on a rear surface of each of the memory chips, and the passivation layer may have a color different from a natural color of single-crystalline silicon.
US08866290B2 Molded heat spreaders
Embodiments of the present disclosure describe techniques and configurations for molded heat spreaders. In some embodiments, a heat spreader includes a first insert having a first face and a first side, the first face positioned to form a bottom surface of a first cavity, and a second insert having a second face and a second side, the second face positioned to form a bottom surface of a second cavity. The second cavity may have a depth that is different from a depth of the first cavity. The heat spreader may further include a molding material disposed between the first and second inserts and coupled with the first side and the second side, the molding material forming at least a portion of a side wall of the first cavity and at least a portion of a side wall of the second cavity. Other embodiments may be described and/or claimed.
US08866289B2 Bonding process and bonded structures
A sealing and bonding material structure for joining semiconductor wafers having monolithically integrated components. The sealing and bonding material are provided in strips forming closed loops. There are provided at least two concentric sealing strips on one wafer. The strips are laid out so as to surround the component(s) on the wafers to be sealed off when wafers are bonded together. The material in the strips is a material bonding the semiconductor wafers together and sealing off the monolithically integrated components when subjected to force and optionally heating. A monolithically integrated electrical and/or mechanical and/or fluidic and/or optical device including a first substrate and a second substrate, bonded together with the sealing and bonding structure, and a method of providing a sealing and bonding material structure on at least one of two wafers and applying a force and optionally heat to the wafers to join them are described.
US08866288B2 Semiconductor package
Disclosed herein is a semiconductor package, including: a first heat radiating plate; a second heat radiating plate formed below the first heat radiating plate; a heat radiating lead formed above the first heat radiating plate and having both ends contacted with the second heat radiating plate; an insulating layer formed above the heat radiating lead; at least one power device formed above the insulating layer; and at least one control device formed above the insulating layer.
US08866287B2 Embedded structures for package-on-package architecture
Electronic assemblies including substrates and their manufacture are described. One assembly includes a die embedded in a dielectric layer in a multilayer substrate, and a dielectric region embedded in the dielectric layer in the multilayer substrate. The multilayer substrate includes a die side and a land side, with the first dielectric region and the dielectric layer extending to the die side. A plurality of vias are positioned within the first dielectric region, the vias extending to pads on the die side. Other embodiments are described and claimed.
US08866284B2 Semiconductor device comprising an extended semiconductor chip having an extension
A semiconductor device includes a first extended semiconductor chip including a first semiconductor chip and an extension extending outwardly from a side surface of the first semiconductor chip. The semiconductor device also includes a second semiconductor chip mounted above the first extended semiconductor chip and electrically connected with the first semiconductor chip. The first extended semiconductor chip includes a first extension electrode pad provided above the extension and electrically connected with an electrode of the first semiconductor chip.
US08866281B2 Three-dimensional integrated circuits and fabrication thereof
A three-dimensional integrated circuit is disclosed, including a first interposer including through substrate vias (TSV) therein and circuits thereon; a plurality of first active dies disposed on a first side of the first interposer, a plurality of first intermediate interposers, each including through substrate vias (TSV), disposed on the first side of the first interposer, and a second interposer including through substrate vias (TSV) therein and circuits thereon supported by the first intermediate interposers.
US08866280B2 Chip package
A chip package comprising a carrier, a chip, a plurality of first conductive elements, an encapsulation, and a conductive film is provided. The carrier has a carrying surface and a back surface opposite to the carrying surface. Furthermore, the carrier has a plurality of common contacts in the periphery of the carrying surface. The chip is disposed on the carrying surface and electrically connected to the carrier. In addition, the first conductive elements are disposed on the common contacts respectively. The encapsulation is disposed on the carrying surface and encapsulating the chip. Moreover, the conductive film is disposed over the encapsulation and the first conductive elements, so as to electrically connect with the common contacts via the first conductive elements. A process for fabricating the chip package is further provided. The chip package is capable of preventing the EMI problem and thus provides superior electrical performance.
US08866279B2 Semiconductor device
A semiconductor device includes: a lead frame; a semiconductor element held by the lead frame; a frame body which is formed on the lead frame to surround the semiconductor element, cover a side surface of the lead frame, and expose a bottom surface of the lead frame; and a protective resin filling a region surrounded by the frame body. The lead frame includes an uneven part formed in a section which is part of an upper surface of the lead frame, and is covered with the frame body.
US08866278B1 Semiconductor device with increased I/O configuration
In accordance with the present invention, there is provided a semiconductor package or device including a uniquely configured leadframe sized and configured to maximize the available number of exposed lands or I/O's in the semiconductor device. More particularly, the semiconductor device of the present invention includes a die pad (or die paddle) defining multiple peripheral edge segments. In addition, the semiconductor device includes a plurality of lands which are provided in a prescribed arrangement. Connected to the top surface of the die pad is at least one semiconductor die which is electrically connected to at least some of the lands. At least portions of the die pad, the lands, and the semiconductor die are encapsulated by the package body, with at least portions of the bottom surfaces of the die pad and the lands being exposed in a common exterior surface of the package body.
US08866260B2 MIM decoupling capacitors under a contact pad
An integrated circuit structure includes one or more external contact pads with decoupling capacitors, such as metal-insulator-metal (MIM) capacitors, formed directly thereunder. In an embodiment, the decoupling capacitors are formed below the first metallization layer, and in another embodiment, the decoupling capacitors are formed in the uppermost inter-metal dielectric layer. A bottom plate of the decoupling capacitors is electrically coupled to one of Vdd and Vss, and the top plate of the decoupling capacitors is electrically coupled to the other. The decoupling capacitors may include an array of decoupling capacitors formed under the external contact pads and may include one or more dummy decoupling capacitors. The one or more dummy decoupling capacitors are MIM capacitors in which at least one of the top plate and the bottom plate is not electrically coupled to an external contact pad.
US08866257B2 System involving electrically reprogrammable fuses
An electrically reprogrammable fuse comprising an interconnect disposed in a dielectric material, a sensing wire disposed at a first end of the interconnect, a first programming wire disposed at a second end of the interconnect, and a second programming wire disposed at a second end of the interconnect, wherein the fuse is operative to form a surface void at the interface between the interconnect and the sensing wire when a first directional electron current is applied from the first programming wire through the interconnect to the second programming wire, and wherein, the fuse is further operative to heal the surface void between the interconnect and the sensing wire when a second directional electron current is applied from the second programming wire through the interconnect to the first programming wire.
US08866255B2 Semiconductor device with staggered oxide-filled trenches at edge region
A semiconductor device is provided that comprises a semiconductor substrate comprising an active area and a peripheral region adjacent the active area and structure positioned in the peripheral region for hindering the diffusion of mobile ions from the peripheral region into the active area.
US08866253B2 Semiconductor arrangement with active drift zone
A semiconductor device arrangement includes a first semiconductor device having a load path and a plurality of second semiconductor devices, each having a load path between a first and a second load terminal and a control terminal. The second semiconductor devices have their load paths connected in series and connected in series to the load path of the first semiconductor device. Each of the second semiconductor devices has its control terminal connected to the load terminal of one of the other second semiconductor devices, and one of the second semiconductor devices has its control terminal connected to one of the load terminals of the first semiconductor device. Each of the second semiconductor devices has at least one device characteristic. At least one device characteristic of at least one of the second semiconductor devices is different from the corresponding device characteristic of others of the second semiconductor devices.
US08866250B2 Multiple metal film stack in BSI chips
A device includes a semiconductor substrate, a black reference circuit in the semiconductor substrate, a metal pad on a front side of, and underlying, the semiconductor substrate, and a first and a second conductive layer. The first conductive layer includes a first portion penetrating through the semiconductor substrate to connect to the metal pad, and a second portion forming a metal shield on a backside of the semiconductor substrate. The metal shield is aligned to the black reference circuit, and the first portion and the second portion are interconnected to form a continuous region. The second conductive layer includes a portion over and contacting the first portion of the first conductive layer, wherein the first portion of the first conductive layer and the portion of the second conductive layer form a first metal pad. A dielectric layer is overlying and contacting the second portion of the first conductive layer.
US08866246B2 Holder on chip module structure
The present invention provides a holder on chip module structure including a substrate. A chip is configured on the substrate, with a sensing area. A holder is disposed on the substrate, wherein a portion of the holder is directly contacted to the chip to reduce the tilt between the chip and the holder. A transparent material is disposed on the holder, substantially aligning to the sensing area. A lens holder is disposed on the holder, and a lens is configured on the lens holder, substantially aligning to the transparent material and the sensing area.
US08866243B2 Ferromagnetic tunnel junction structure and magnetoresistive element using the same
For the present ferromagnetic tunnel junction structure, employed is a means characterized by using an MgO barrier and using a Co2FeAl full-Heusler alloy for any of the ferromagnetic layers therein. The ferromagnetic tunnel junction structure is characterized in that Co2FeAl includes especially a B2 structure and one of the ferromagnetic layers is formed on a Cr buffer layer. The magnetoresistive element is characterized in that the ferromagnetic tunnel junction structure therein is any of the above-mentioned ferromagnetic tunnel junction structure. Accordingly, a large TMR, especially a TMR over 100% at room temperature can be attained, using Co2FeAl having a smallest α though not a half-metal.
US08866242B2 MTJ structure and integration scheme
A memory device may comprise a magnetic tunnel junction (MTJ) stack, a bottom electrode (BE) layer, and a contact layer. The MTJ stack may include a free layer, a barrier, and a pinned layer. The BE layer may be coupled to the MTJ stack, and encapsulated in a planarized layer. The BE layer may also have a substantial common axis with the MTJ stack. The contact layer may be embedded in the BE layer, and form an interface between the BE layer and the MTJ stack.
US08866239B2 IC manufacturing method, IC and apparatus
A method of manufacturing an integrated circuit having a substrate comprising a plurality of components and a metallization stack over the components, the metallization stack comprising a first sensing element and a second sensing element adjacent to the first sensing element.
US08866238B2 Hybrid integrated component and method for the manufacture thereof
Hybrid integrated components including an MEMS element and an ASIC element are described, whose capacitor system allows both signal detection with comparatively high sensitivity and sensitive activation of the micromechanical structure of the MEMS element. The hybrid integrated component includes an MEMS element having a micromechanical structure which extends over the entire thickness of the MEMS substrate. At least one structural element of this micromechanical structure is deflectable and is operationally linked to at least one capacitor system, which includes at least one movable electrode and at least one stationary electrode. Furthermore, the component includes an ASIC element having at least one electrode of the capacitor system. The MEMS element is mounted on the ASIC element, so that there is a gap between the micromechanical structure and the surface of the ASIC element. According to the invention, at least one electrode of the capacitor system is separated from the layered structure of the ASIC element and instead mechanically and electrically connected to the deflectable structural element of the MEMS element, so that this electrode functions as a movable electrode of the capacitor system.
US08866231B2 Nitride semiconductor device
A nitride semiconductor device includes: first electrode interconnect layers extending in parallel with one another over the nitride semiconductor layer and divided by areas extending across a longitudinal direction of the first electrode interconnect layers; first gate electrodes extending along the first electrode interconnect layers; first gate electrode connecting interconnects extending in associated ones of the areas dividing the first electrode interconnect layers and being in connection to the first gate electrodes; first electrode connecting interconnects formed above the first gate electrode connecting interconnects and being in connection to the first electrode interconnect layers; a first electrode upper interconnects formed on the first electrode connecting interconnects with an interconnect insulating film interposed therebetween, and being in connection to the first electrode connecting interconnects through associated ones of openings of the interconnect insulating film.
US08866223B2 Process for manufacturing a power semiconductor device having charge-balance columnar structures on a non-planar surface, and corresponding power semiconductor device
An embodiment of a process for manufacturing a power semiconductor device envisages the steps of: providing a body of semiconductor material having a top surface and having a first conductivity; forming columnar regions having a second type of conductivity within the body of semiconductor material, and surface extensions of the columnar regions above the top surface; and forming doped regions having the second type of conductivity, in the proximity of the top surface and in contact with the columnar regions. The doped regions are formed at least partially within the surface extensions of the columnar regions; the surface extensions and the doped regions have a non-planar surface pattern, in particular with a substantially V-shaped groove.
US08866221B2 Super junction semiconductor device comprising a cell area and an edge area
A drift layer of a super junction semiconductor device includes first portions of a first conductivity type and second portions of a second conductivity type opposite to the first conductivity type. The first and second portions are formed both in a cell area and in an edge area surrounding the cell area, wherein an on-state or forward current through the drift layer flows through the first portions in the cell area. At least one of the first and second portions other than the first portions in the cell area includes an auxiliary structure or contains auxiliary impurities to locally reduce the avalanche rate. Locally reducing the avalanche rate increases the total voltage blocking capability of the super junction semiconductor device.
US08866212B2 Structures and methods of improving reliability of non-volatile memory devices
In one example, the memory device disclosed herein includes a gate insulation layer and a charge storage layer positioned above the gate insulation layer, wherein the charge storage layer has a first width. The device further includes a blocking insulation layer positioned above the charge storage layer and a gate electrode positioned above the blocking insulation layer, wherein the gate electrode has a second width that is greater than the first width. An illustrative method disclosed herein includes forming a gate stack for a memory device, wherein the gate stack includes a gate insulation layer, an initial charge storage layer, a blocking insulation layer and a gate electrode, and wherein the initial charge storage layer has a first width. The method further includes performing an etching process to selectively remove at least a portion of the initial charge storage layer so as to produce a charge storage layer having a second width that is less than the first width of the initial charge storage layer.
US08866211B2 Nonvolatile memory device and method of manufacturing same
A nonvolatile memory device including a cell array area in which a plurality of unit cells are arranged at least in one direction includes a plurality of memory transistors formed in the respective unit cells. Each memory transistor includes a gate pattern in which a tunnel insulating layer, a floating gate, an inter-gate insulating layer, and a control gate are laminated, and first and second junction areas arranged on opposite sides of the gate pattern, wherein the gate patterns are separated in the one direction by unit cells. The nonvolatile memory device also includes a first conduction interconnection which extends in the one direction and is arranged in a position that overlaps the control gate and a plurality of first contacts, at least one of which is arranged for each of the control gates to connect the control gates and the first conduction interconnection.
US08866208B2 Semiconductor devices including vertical transistors and methods of fabricating the same
A semiconductor device includes a first capacitor in a trench of a semiconductor substrate and an active pillar disposed on the semiconductor substrate opposite the first capacitor. The active pillar includes first region, first channel region, second region, second channel region and third region, sequentially stacked. A pillar connection pattern electrically connects the first capacitor to a first source region. A first gate electrode is disposed on a sidewall of the first channel region. A common drain region is disposed in the second region, and a common bit line is disposed on a sidewall of the common drain region. A second gate electrode is disposed on a sidewall of the second channel region, and a second source region is disposed in the third region. A second capacitor is disposed on a top surface of the second source region opposite the second channel region.
US08866204B2 Method to form finFET/trigate devices on bulk semiconductor wafers
A method for fabricating a finFET device having an insulating layer that insulates the fin from a substrate is described. The insulating layer can prevent leakage current that would otherwise flow through bulk semiconductor material in the substrate. The structure may be fabricated starting with a bulk semiconductor substrate, without the need for a semiconductor-on-insulator substrate. Fin structures may be formed by epitaxial growth, which can improve the uniformity of fin heights in the devices.
US08866203B2 Method for forming compound epitaxial layer by chemical bonding and epitaxy product made by the same method
The present invention is to provide a method for forming a compound epitaxial layer by chemical bonding, which comprises the steps of forming a contact layer on a substrate; chemically reacting atoms on a surface of the contact layer with non-metal atoms, such that the non-metal atoms form non-metal ions for chemically bonding to the atoms on the surface of the contact layer; exciting the non-metal ions by energy excitation, such that unpaired electrons of the non-metal ions not yet bound to the atoms on the surface of the contact layer become dangling bonds; and conducting chemical vapor deposition by introducing an organic metal compound and a reactant gas, wherein metal ions of the organic metal compound are bound to the dangling bonds by electric dipole attraction, and anions of the reactant gas are bound to the metal ions by ionic bonding, such that the compound epitaxial layer is formed.
US08866201B2 High-voltage transistor device with integrated resistor
A high-voltage device structure comprises a resistor coupled to a tap transistor that includes a JFET in a configuration wherein a voltage provided at a terminal of the JFET is substantially proportional to an external voltage when the external voltage is less than a pinch-off voltage of the JFET. The voltage provided at the terminal being substantially constant when the external voltage is greater than the pinch-off voltage. One end of the resistor is substantially at the external voltage when the external voltage is greater than the pinch-off voltage. When the external voltage is negative, the resistor limits current injected into the substrate. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure.
US08866192B1 Semiconductor device, high electron mobility transistor (HEMT) and method of manufacturing
A semiconductor device includes a substrate, a channel layer formed over the substrate, an active layer formed over the channel layer, and a gate structure formed over the active layer. The active layer is configured to cause a two dimensional electron gas (2DEG) to be formed in the channel layer along an interface between the channel layer and the active layer. The gate structure is configured to deplete the 2DEG under the gate structure. The active layer has a negatively charged region under the gate structure. The negatively charged region is configured to further deplete the 2DEG under the gate structure.
US08866191B2 HEMT semiconductor component with field plates
A transistor in which the electric field is reduced in critical areas using field plates, permitting the electric field to be more uniformly distributed along the component, is provided, wherein the electric field in the active region is smoothed and field peaks are reduced. The semiconductor component has a substrate with an active layer structure, a source contact and a drain contact located on said active layer structure. The source contact and the drain contact are mutually spaced and at least one part of a gate contact is provided on the active layer structure in the region between the source contact and the drain contact, a gate field plate being electrically connected to the gate contact. In addition, at least two separate field plates are placed directly on the active layer structure or directly on a passivation layer.
US08866188B1 Semiconductor devices and methods of manufacture thereof
Semiconductor devices and methods of manufacture thereof are disclosed. In one embodiment, a method of manufacturing a semiconductor device includes forming a channel region in a workpiece, and forming a source or drain region proximate the channel region. The source or drain region includes a contact resistance-lowering material layer comprising SiP, SiAs, or a silicide. The source or drain region also includes a channel-stressing material layer comprising SiCP or SiCAs.
US08866183B2 LED module
An LED module includes: a package having electrodes provided on the outer surface of opposing sidewalls, and a light-emitting element connected to the electrodes and mounted on the package; a base member having a copper metal; an insulating layer stacked on the surface of the base member and having an insulating material; and a conductive wiring pattern connected to the electrodes by soldering and formed on the surface of the insulating layer. The insulating layer has a through-hole formed by removing a part of the section where the package is positioned, and a heat dissipation unit formed by soldering between the back surface of the package and the base member, which face one another with the through-hole interposed therebetween.
US08866178B2 Light emitting device
A light emitting device may be provided that includes a conductive support member, a first conductive layer, a second conductive layer, an insulation layer between the first conductive layer and the second conductive layer, and a light emitting structure that includes a second semiconductor layer on the second conductive layer, a first semiconductor layer, and an active layer between the first semiconductor layer and the second semiconductor layer. The first conductive layer may include at least one conductive via that passes through the second conductive layer, the second semiconductor layer and the active layer. A top surface of the at least one conductive via is provided into the first semiconductor layer. The insulation layer may substantially surround a side wall of the conductive via.
US08866176B2 Display device
A structure of an EL display device which has an increased display area is provided. Further, a structure of an EL display device which has a high definition display is provided. An auxiliary electrode is formed over a first partition and side surfaces of the auxiliary electrode are covered with a second partition. A top surface of the auxiliary electrode is in contact with the conductive film which is one electrode of a light-emitting element and has a light-transmitting property, which enables a large-area display. Further, even the distance between the adjacent light-emitting elements is shortened, the auxiliary electrode can be provided between the adjacent light-emitting elements, which enables a high definition display.
US08866175B2 Optoelectronic semiconductor chip
An optoelectronic semiconductor chip includes a semiconductor layer sequence and a carrier substrate. A first and a second electrical contact layer are arranged at least in regions between the carrier substrate and the semiconductor layer sequence and are electrically insulated from one another by an electrically insulating layer. A mirror layer is arranged between the semiconductor layer sequence and the carrier substrate. The mirror layer adjoins partial regions of the first electrical contact layer and partial regions of the electrically insulating layer. The partial regions of the electrically insulating layer which adjoin the mirror layer are covered by the second electrical contact layer in such a way that at no point do they adjoin a surrounding medium of the optoelectronic semiconductor chip.
US08866167B2 Nitride semiconductor light emitting device and fabrication method thereof
The present invention relates to a GaN based nitride based light emitting device improved in Electrostatic Discharge (ESD) tolerance (withstanding property) and a method for fabricating the same including a substrate and a V-shaped distortion structure made of an n-type nitride semiconductor layer, an active layer and a p-type nitride semiconductor layer on the substrate and formed with reference to the n-type nitride semiconductor layer.
US08866157B2 Semiconductor device and method of fabricating the semiconductor device
A semiconductor device may include a first semiconductor layer formed on a substrate, a second semiconductor layer formed on the first semiconductor layer, a source electrode and a drain electrode in contact with the first semiconductor layer or the second semiconductor layer, an opening formed in the second semiconductor layer, an insulating film formed on an inner surface of the opening formed in the second semiconductor layer and above the second semiconductor layer, a gate electrode formed in the opening via the insulating film, and a protective film formed on the insulating film and including an amorphous film containing carbon as a major component.
US08866152B2 Betavoltaic apparatus and method
An exemplary thinned-down betavoltaic device includes an N+ doped silicon carbide (SiC) substrate having a thickness between about 3 to 50 microns, an electrically conductive layer disposed immediately adjacent the bottom surface of the SiC substrate; an N− doped SiC epitaxial layer disposed immediately adjacent the top surface of the SiC substrate, a P+ doped SiC epitaxial layer disposed immediately adjacent the top surface of the N− doped SiC epitaxial layer, an ohmic conductive layer disposed immediately adjacent the top surface of the P+ doped SiC epitaxial layer, and a radioisotope layer disposed immediately adjacent the top surface of the ohmic conductive layer. The radioisotope layer can be 63Ni, 147Pm, or 3H. Devices can be stacked in parallel or series. Methods of making the devices are disclosed.
US08866151B2 Semiconductor device
According to one embodiment, a semiconductor device includes a semiconductor layer of a first conductivity type, a first region of a second conductivity type selectively provided in a first major surface of the semiconductor layer, a second region of the second conductivity type selectively provided in the first major surface and connected to the first region, a first electrode provided in contact with the semiconductor layer and the first region, a second electrode provided in contact with the second region, and a third electrode electrically connected to a second major surface of the semiconductor layer opposite to the first major surface.
US08866150B2 Silicon carbide power devices including P-type epitaxial layers and direct ohmic contacts
A silicon carbide power device is fabricated by forming a p-type silicon carbide epitaxial layer on an n-type silicon carbide substrate, and forming a silicon carbide power device structure on the p-type silicon carbide epitaxial layer. The n-type silicon carbide substrate is at least partially removed, so as to expose the p-type silicon carbide epitaxial layer. An ohmic contact is formed on at least some of the p-type silicon carbide epitaxial layer that is exposed. By at least partially removing the n-type silicon carbide substrate and forming an ohmic contact on the p-type silicon carbide epitaxial layer, the disadvantages of using a p-type substrate may be reduced or eliminated. Related structures are also described.
US08866145B2 Organic light-emitting display device including an insulating layer having different thicknesses
An organic light-emitting display device includes a buffer layer on a substrate that has a plurality of insulating layers having different refractive indexes, and at least one of the insulating layers have different thicknesses on the same level. The device further includes an active layer of a thin film transistor in a thick area of the buffer layer, a pixel electrode in a thin area of the buffer layer, a gate electrode of the thin film transistor on the active layer and source and drain electrodes of the thin film transistor connected to the active layer, and a gate insulating layer between the gate electrode and the source and drain electrodes. The device also includes an emission layer on the pixel electrode, an opposite electrode facing the pixel electrode, and the emission layer is between the opposite electrode and the pixel electrode.
US08866142B2 Display device and manufacturing method thereof
The present invention relates to a display device and a manufacturing method thereof. A display device according to an exemplary embodiment of the present invention includes a substrate including a first surface and a second surface, a first line disposed on the first surface and made of a transparent metal oxide semiconductor, and a first semiconductor disposed on the first surface and made of the transparent metal oxide semiconductor.
US08866141B2 Thin film transistor and method for fabricating the same
A thin film transistor and a method for fabricating the same are disclosed. The thin film transistor includes: a gate electrode formed on a substrate and having a plurality of horizontal electrode parts spaced apart at regular intervals; a gate insulating film formed over the entire surface of the substrate including the gate electrode; an active pattern formed on the gate insulating film above the plurality of horizontal electrode parts; an etch stop film pattern formed above the active pattern and the gate insulating film so as to overlap top portions of the active pattern and the gate electrode and; a source electrode formed on the active pattern, the gate insulating film, and the etch stop film pattern so as to overlap top portions of adjacent horizontal electrode parts; and a drain electrode formed on the active pattern, the gate insulating film, and the etch stop film pattern so as to overlap top portions of horizontal electrode parts located on the outermost ends.
US08866140B2 Thin-film transistor
Making it possible to improve adhesion between the semiconductor layer and the electrodes, realize high-speed operation of the thin-film transistor by enhancing ohmic contact between these members, reliably prevent oxidation of the electrode surfaces, and realize an electrode fabrication process with few processing steps. The thin-film transistor 10 of the present invention includes a semiconductor layer 4 composed of oxide semiconductor, a source electrode 5 and a drain electrode 6 that are layers composed mainly of copper, and oxide reaction layers 22 provided between the semiconductor layer 4 and each of the source electrode 5 and drain electrode 6, and high-conductance layers 21 provided between the oxide reaction layers 22 and semiconductor layer 4.
US08866137B2 Thin film transistor array panel and manufacturing method thereof
A thin film transistor array panel includes: a gate electrode disposed on an insulation substrate; a gate insulating layer disposed on the gate electrode; a first electrode and an oxide semiconductor disposed directly on the gate insulating layer; a source electrode and a drain electrode formed on the oxide semiconductor; a passivation layer disposed on the first electrode, the source electrode, and the drain electrode; and a second electrode disposed on the passivation layer.
US08866136B2 Transistor, method of manufacturing the transistor and electronic device including the transistor
Provided are a transistor, a method of manufacturing the transistor, and an electronic device including the transistor. The transistor may include a passivation layer on a channel layer, a source, a drain, and a gate, wherein the component of the passivation layer is varied in a height direction. The passivation layer may have a multi-layer structure including a silicon oxide layer, a silicon oxynitride layer, and a silicon nitride layer sequentially stacked. The channel layer may include an oxide semiconductor.
US08866134B2 Light-emitting device and photovoltaic cell, and method for manufacturing the same
Provided are a light-emitting device and a photovoltaic cell having excellent characteristics. A light-emitting device (10) includes a cathode (34), an anode (32), a light-emitting layer (50) interposed between the cathode (34) and the anode (32), and an electron injection layer (44) provided between the cathode (34) and the light-emitting layer (50) and connected to the cathode (34), in which at least one of the anode (32) and the cathode (34) contains a conductive material having an aspect ratio of 1.5 or more, and the electron injection layer (44) contains an organic compound having at least one of an ionic group and a polar group.
US08866132B2 Semiconductor device and electronic unit
Thin-film transistors and techniques for forming thin-film transistors (TFT). In some embodiments, there is provided a method of forming a TFT, comprising forming a body region of the TFT comprising an organic semiconducting material, and forming a protective layer comprising an organic insulating material. Forming the protective layer comprises contacting the body region of the TFT with a solution comprising the organic insulating material. The organic insulating material is a material that phase separates with the organic semiconducting material when the solution contacts the organic semiconducting material. In other embodiments, there is provided an apparatus comprising a TFT. The TFT comprises a body region comprising an organic semiconducting material and a protective layer contacting the body region and comprising an organic insulating material that, when a solution comprising the organic insulating material contacts the organic semiconducting material, causes the organic insulating material to phase separate with the organic semiconducting material.
US08866128B2 Organic electroluminescent device and preparation method thereof
The present invention relates to a method capable of considerably improving the characteristics of an organic electroluminescent device. The present invention provides a method capable of reducing operating voltage and improving efficiency by inserting an inorganic oxide interlayer configured of at least one layer between light-emitting layers.
US08866127B2 Nitride semiconductor light-emitting element including Si-doped layer, and light source
A nitride semiconductor light-emitting element uses a non-polar plane as its growing plane. A GaN/InGaN multi-quantum well active layer includes an Si-doped layer which is arranged in an InyGa1-yN (where 0
US08866124B2 Diodes with native oxide regions for use in memory arrays and methods of forming the same
In a first aspect, a vertical semiconductor diode is provided that includes (1) a first semiconductor layer formed above a substrate; (2) a second semiconductor layer formed above the first semiconductor layer; (3) a first native oxide layer formed above the first semiconductor layer; and (4) a third semiconductor layer formed above the first semiconductor layer, second semiconductor layer and first native oxide layer so as to form the vertical semiconductor diode that includes the first native oxide layer. Numerous other aspects are provided.
US08866122B1 Resistive switching devices having a buffer layer and methods of formation thereof
In one embodiment, a resistive switching device includes a bottom electrode, a switching layer, a buffer layer, and a top electrode. The switching layer is disposed over the bottom electrode. The buffer layer is disposed over the switching layer and provides a buffer of ions of a memory metal. The buffer layer includes an alloy of the memory metal with an alloying element, which includes antimony, tin, bismuth, aluminum, germanium, silicon, or arsenic. The top electrode is disposed over the buffer layer and provides a source of the memory metal.
US08866119B2 Memory device and method for manufacturing same
According to one embodiment, a memory device includes a selection element layer, a nanomaterial aggregate layer, and a fine particle. The nanomaterial aggregate layer is stacked on the selection element layer. The nanomaterial aggregate layer has a plurality of micro conductive bodies aggregated with an interposed gap. The fine particle has at least a surface made of silicon oxynitride. The fine particle is dispersed between the micro conductive bodies in one portion of the nanomaterial aggregate layer piercing the nanomaterial aggregate layer in a thickness direction.
US08866117B2 Semiconductor storage device including a diode and a variable resistance element
A diode layer includes a first impurity semiconductor layer that includes a first impurity acting as an acceptor and a second impurity semiconductor layer that includes a second impurity acting as a donor. One end of a first electrode layer contacts the diode layer. One end of a polysilicon layer contacts the other end of the first electrode layer. One end of a variable resistance layer contacts the other end of the polysilicon layer and is able to change a resistance value. A second electrode layer contacts the other end of the variable resistance layer. At least one of a first area and a second area contains a third impurity. The first area includes one end of the polysilicon layer, the second area includes the other end of the polysilicon layer. The third impurity differs from the first impurity and the second impurity.
US08866116B2 Semiconductor memory devices having predetermined conductive metal levels and methods of fabricating the same
A semiconductor memory device includes a lower wiring disposed on a first region of a substrate and a gate electrode disposed on a second region of the substrate. The lower wiring includes substantially the same conductive material as the gate electrode. A wiring-insulating layer is interposed between the lower wiring and the substrate, and a gate insulating layer is interposed between the gate electrode and the substrate. A diode is disposed on the lower wiring, and a variable resistance element is electrically coupled to the diode.
US08866113B2 Electrical isolator circuit
The invention discloses an electrical isolator circuit comprising: an input stage comprising a transmitter of an opto-isolator; and an output stage comprising: a receiver of the opto-isolator; an active circuit in series with the receiver between the receiver and a power rail of the output stage; a first resistor connected to an output of the active circuit, and an input for the application of a predetermined voltage to the active circuit, the output stage being configured such that a varying output voltage is developed across the first resistor in response to input of a high voltage AC signal to the input stage. Ideally the output stage is operable to clamp the voltage across the receiver at the level of the predetermined voltage, thereby allowing for an increase in the load resistor and variable output resistor without increasing the time constant to unacceptably having regards to switching requirements.
US08866111B2 Radiation source and method for lithographic apparatus and device manufacturing method
A radiation source for generating EUV from a stream of molten fuel droplets by LPP (Laser Produced Plasma) or (Dual Laser Plasma) has a fuel droplet generator arranged to provide a stream of droplets of fuel and at least one laser configured to vaporize at least some of the droplets of fuel, whereby radiation is generated. The fuel droplet generator has a nozzle, a feed chamber, and a reservoir, with a pumping device arranged to supply a flow of fuel in molten state from the reservoir through the feed chamber and out of the nozzle as a stream of droplets. The feed chamber has an outer face in contact with a drive cavity filled with a liquid, and the liquid is driven to oscillate by a vibrator with the oscillation transmissible to the molten fuel in the feed chamber from the outer face of the feed chamber through the liquid.
US08866109B2 Charged-particle beam irradiation device
A charged-particle beam irradiation device, which irradiates an irradiation target with a charged-particle beam, includes a transport line that transports the charged-particle beam and a rotating gantry that is rotatable about a rotation axis. The transport line includes an inclination portion making the charged-particle beam travel so that the charged-particle beam is inclined to be separated from the rotation axis, and is formed to turn the charged-particle beam in a rotation direction of the rotation axis and to bend the charged-particle beam, which has turned in the rotation direction, toward the rotation axis. The rotating gantry is formed of a cylindrical portion that receives the irradiation target and supports the transport line. The inclination portion is disposed in the cylindrical portion of the rotating gantry. The charged-particle beam irradiation device further includes blocking members that block radiation emitted from the transport line disposed in the cylindrical portion.
US08866107B2 Wavefront compensation for deep tissue optical microscopy
Wavefront distortions of an optical beam are measured. The transverse optical modes of the optical beam are partitioned into a plurality of subsets of transverse optical modes, one of the subsets of transverse optical modes is selected as the current subset, and the optical beam is modulated based on the current subset by maintaining the transverse optical modes of the optical beam that are outside the current subset stable, and modulating the transverse optical modes of the optical beam within the current subset. A non-linear optical signal is generated from the modulated optical beam by directing the modulated optical beam through a non-linear optical system that includes a random scattering medium, the power of the generated non-linear optical signal is measured, and, based on the measured power, values of the spatial phase for the optical beam at transverse optical modes are extracted within the current subset.
US08866105B2 Sleeve holder assembly
A sleeve holder assembly for a radiation source is disclosed. The sleeve holder assembly comprises: an elongate radiation transparent sleeve element; a sleeve holder receptacle portion coupled to the elongate radiation transparent sleeve element; a sleeve bolt assembly portion coupled to the sleeve holder receptacle portion; a first sealing element disposed between the sleeve holder receptacle portion and the sleeve bolt assembly portion; and a locking element configured to prevent decoupling of the sleeve bolt assembly portion and the sleeve holder receptacle portion. The first sealing element is configured to provide a substantially fluid impermeable seal between the elongate radiation transparent sleeve element and the sleeve holder receptacle portion.
US08866102B2 Electron beam device with tilting and dispersion compensation, and method of operating same
An electron beam device 100 includes: a beam emitter 102 for emitting a primary electron beam 101; an objective electron lens 127 for focusing the primary electron beam 101 onto a specimen 130, the objective lens defining an optical axis 126; a beam tilting arrangement 103 configured to direct the primary electron beam 101 to the electron lens 127 at an adjustable offset from the optical axis 126 such that the objective electron lens 127 directs the electron beam 101 to strike the specimen 130 at an adjustable oblique beam landing angle, whereby a chromatic aberration is caused; a beam separator 115 having a first dispersion for separating a signal electron beam 135 from the primary electron beam 101; and a dispersion compensation element 104 adapted to adjust a compensation dispersion of the primary electron beam 101 so as to compensate for a beam aberration resulting from the first dispersion and from the chromatic aberration.
US08866099B2 Radiographic detector arrays including scintillators and methods for same
A projection radiographic imaging apparatus includes an imaging array with imaging pixels formed over an insulating substrate. A scintillator converts radiographic radiation to photoelectric radiation proximate to the imaging array. A dielectric layer disposed between the scintillator and the imaging array has a dielectric constant less than 3.0. A continuous or patterned anti-static layer disposed between the imaging array and the scintillator is connected to one or more conductive traces in the imaging array.
US08866097B2 Detector apparatus having a hybrid pixel-waveform readout system
A gamma ray detector apparatus comprises a solid state detector that includes a plurality of anode pixels and at least one cathode. The solid state detector is configured for receiving gamma rays during an interaction and inducing a signal in an anode pixel and in a cathode. An anode pixel readout circuit is coupled to the plurality of anode pixels and is configured to read out and process the induced signal in the anode pixel and provide triggering and addressing information. A waveform sampling circuit is coupled to the at least one cathode and configured to read out and process the induced signal in the cathode and determine energy of the interaction, timing of the interaction, and depth of interaction.
US08866092B2 Radiation detection system and a method of using the same
A radiation detection system can include a scintillator that is capable of emitting scintillating light in response to capturing different types of targeted radiation, a photosensor optically coupled to the scintillator, and a control module electrically coupled to the photosensor. The control module can be configured to analyze state information of the radiation detection system, and select a first technique to determine which type of targeted radiation is captured by the scintillator, wherein the first technique is a particular technique of a plurality of techniques to determine which type of targeted radiation was captured by the scintillator, and the selection is based at least in part on the analysis. In an embodiment, the radiation detection system can be used to change from one technique to another in real time or near real time to allow the radiation detection system to respond to changing conditions.
US08866091B2 Method and apparatus for acquiring images created by penetration of radioactive ray
Disclosed is an apparatus and method of acquiring images created by penetration of a radioactive ray. The apparatus includes a scintillator to generate a light signal in response to an irradiated radioactive ray, and to change an advancing direction of the generate light signal, a light receiving unit to receive the light signal whose advancing direction is changed, and a signal processing unit to convert the received light signal into an electrical signal, and acquire an image corresponding to the penetrated irradiated radioactive ray based on the converted electrical signal.
US08866087B2 Systems and methods for improving the quality of images in a PET scan
Systems, devices and methods of reconstructing an image from a positron emission tomography scan that may include detecting a plurality of photons selected from scattered photons and unscattered photons by a plurality of detectors, identifying a time interval for each of the plurality of photons by a processing device, matching each of the plurality of photons into a plurality of pairs of coincident photons based upon a substantially simultaneous time interval identified by the processing device, measuring an energy produced by each of the plurality of photons by the plurality of detectors, determining a scattering angle for each pair of coincident photons from an annihilation point relative to the position of the plurality of detectors by the processing device based on the energy produced and reconstructing an image using a reconstruction algorithm, wherein the reconstruction algorithm uses the scattering angle of each pair of coincident photons.
US08866083B2 Alarm
An optical smoke detector (10) is provided that comprises a light source (154), a light receiver (172), and a control circuit (130) for controlling operation of the detector. The control circuit (130) is configured to apply an unregulated voltage to the light source to cause it to emit light, to monitor the current through said light source (154) so as to monitor the light emitted by said light source (154); and to monitor the current generated by light received by said light receiver (172) so as to monitor the light received by said light receiver (172). The control circuit (130) generates a ratio signal representative of the ratio of the monitored currents; and compares the ratio signal with a reference value and generate a smoke detection signal in dependence thereon.
US08866082B2 Electromagnetic radiation detector with micro-encapsulation, and device for detecting electromagnetic radiation using such detectors
This electromagnetic radiation detector consists of a plurality of elementary detection micro-sites, each including a micro-detector provided with a membrane (2) that is sensitive to the radiation in question and each being provided in a micro-cavity or micro-capsule defined by a substrate (1), by an upper wall (5) used as a window that is transparent to said radiation and by side walls (4), said membrane (2) being suspended above substrate (1) by means of at least two support arms (6) that include an electrically conducting layer (17), with the ends of said arms (6) being anchored in side walls (4).
US08866081B2 High density faraday cup array or other open trench structures and method of manufacture thereof
A detector array and method for making the detector array. The detector array includes a substrate including a plurality of trenches formed therein, and a plurality of collectors electrically isolated from each other, formed on the walls of the trenches, and configured to collect charged particles incident on respective ones of the collectors and to output from the collectors signals indicative of charged particle collection. In the detector array, adjacent ones of the plurality of trenches are disposed in a staggered configuration relative to one another. The method forms in a substrate a plurality of trenches across a surface of the substrate such that adjacent ones of the trenches are in a staggered sequence relative to one another, forms in the plurality of trenches a plurality of collectors, and connects a plurality of electrodes respectively to the collectors.
US08866080B2 Faraday cup array integrated with a readout IC and method for manufacture thereof
A detector array and method for making the detector array. The array includes a substrate including a plurality of trenches formed therein, and includes a plurality of collectors electrically isolated from each other, formed on the walls of the trenches, and configured to collect charge particles incident on respective ones of the collectors and to output from said collectors signals indicative of charged particle collection. The array includes a plurality of readout circuits disposed on a side of the substrate opposite openings to the collectors. The readout circuits are configured to read charge collection signals from respective ones of the plurality of collectors.
US08866076B2 Multi-pole ion trap for mass spectrometry
An ion trap includes a containment region for containing ions, and a plurality of electrodes positioned on a regular polyhedral structure encompassing the containment region. An electrode is positioned on each vertex of the encompassing structure and at least one of the polygonal surfaces includes additional electrodes configured to form a plurality of quadrupoles on the surface. Alternating RF voltage is applied to the plurality of electrodes, so that directly neighboring electrodes are of equal amplitude and opposite polarity at any point in time. This configuration on the polyhedral structure forms a potential barrier for repelling the ions from each of the regular polygonal surfaces and containing them in the trap. Mass selective filters can be formed from the quadrupoles for parallel mass analysis in different m/z windows. Application of a small DC potential to a plate electrode outside the quadrupoles preferentially depletes single charged ions for enhanced signal-to-noise analysis.
US08866073B2 Ion trap mobility spectrometer and method of using the same
An apparatus for detecting constituents in a sample includes a casing and an ionization chamber defined by the casing. The apparatus also includes an ion collector positioned downstream of the ionization chamber. The apparatus further includes a spectral analysis device coupled to the ion collector. The spectral analysis device is configured to generate a detection spectrum representative of ions collected at the ion collector. The detection spectrum includes an analyte peak portion and a peak tailing portion. The apparatus also includes a control system that is configured to generate a first pulse having a first polarity to initiate a discharge of stored ions from the ionization chamber. The control system is also configured to generate a second pulse substantially immediately after the first pulse. The second pulse has a second polarity opposite the first polarity and is configured to reduce the peak tailing portion.
US08866070B2 Mass spectrometer
A mass spectrometer of reduced size and weight is provided which is capable to conduct highly accurate mass spectroscopy. The mass spectrometer includes an ion source adapted to ionize gas flowing in from outside in order to ionize a measurement sample and a mass spectroscopy section for separating the ionized measurement sample. The ion source has its interior reduced in pressure by differential pumping from the mass spectroscopy section and ionizes the gas when the interior pressure rises as it inhales the gas, and the mass spectroscopy section separates the ionized measurement sample when its interior pressure falls after inhale of the gas. The mass spectrometer may further include a restriction device for suppressing a flow rate of the gas the ion source inhales and an open/close device for opening and closing a flow of the gas the ion source inhales.
US08866068B2 Ion source with cathode having an array of nano-sized projections
An ion source for use in a particle accelerator includes at least one cathode. The at least one cathode has an array of nano-sized projections and an array of gates adjacent the array of nano-sized projections. The array of nano-sized projections and the array of gates have a first voltage difference such that an electric field in the cathode causes electrons to be emitted from the array of nano-sized projections and accelerated downstream. There is a ion source electrode downstream of the at least one cathode, and the at least one cathode and the ion source electrode have the same voltage applied such that the electrons enter the space encompassed by the ion source electrode, some of the electrons as they travel within the ion source electrode striking an ionizable gas to create ions.
US08866065B2 Nanowire arrays comprising fluorescent nanowires
Described herein is a nanowire array, comprising a substrate, a plurality of fluorescent nanowires extending essentially perpendicularly from the substrate and a reflective layer disposed on the substrate in areas between the fluorescent nanowires; wherein the fluorescent nanowires are operable to fluoresce at a wavelength of a collective mode of the nanowire array.
US08866063B2 Lens-free wide-field super-resolution imaging device
A system for imaging objects within a sample includes an image sensor and a sample holder configured to hold the sample, the sample holder disposed adjacent to the image sensor. The system further includes an illumination source configured to scan in two or three dimensions relative to the sensor array and illuminate the sample at a plurality of different locations. The illumination source may include, by way of example, LEDs, laser diodes, or even a screen or display from a portable electronic device. The system includes least one processor configured to reconstruct an image of the sample based on the images obtained from illumination source at the plurality of different scan positions.
US08866059B2 Solid state imaging device and differential circuit having an expanded dynamic range
A solid-state imaging device that is configurable into a small size appropriate for expanding dynamic range includes: a photodiode which is a photoelectric conversion unit that generates charge by incident light; a MOS transistor which is connected to the photodiode and transfers the charge; a floating diffusion region which is a first accumulation unit which accumulates the charge via the MOS transistor; a MOS transistor which is a second transfer unit connected to the floating diffusion region and connected in series to the MOS transistor; and a MOS transistor which is an output unit which outputs, via the MOS transistor, a signal voltage in accordance with an amount of the charge.
US08866055B2 Microwave splatter prevention fabric cover and method
The present disclosure describes a fabric cover for covering objects in a microwave. In an exemplary embodiment, the fabric cover is a fitted fabric cover (preferably made from organic or natural cotton material) that has a drawstring that can be used to secure the cover over a microwavable item. The fabric cover for microwave allows for food to be heated and keeps the microwave clean by covering the food and preventing it from splattering the inside of the microwave.
US08866052B2 Heating articles using conductive webs
A heating article is provided including a heating element including a first layer of nonwoven fibers mixed with conductive fibers, wherein the layer is divided to include a conductive region and a nonconductive region, wherein the conductive region extends in a co-extensive and co-planar pattern in a majority of the layer, and wherein the conductive region has first and second ends, and a power source removably coupled to the first and second ends. The first layer can include nonwoven fibers mixed with non-metallic conductive fibers. The heating article can also include a second layer superposed with the first layer, wherein the second layer is substantially free of non-metallic conductive fibers.
US08866051B2 Apparatus and method for applying a protective element on an optical waveguide
A device and a method are provided, for shrinking a protective element (101) shrinkable by means of the supply of heat onto an optical waveguide (100). The method involves generating thermal radiation, reflecting it and focusing it onto a focus zone in which the protective element (101) is held. The device contains a heating element (10), which generates thermal radiation, a reflector (30), which focuses the thermal radiation emitted by the heating element onto the focus zone, and a mount (20), by means of which the protective element (101) can be held in the focus zone.
US08866049B1 Methods of selectively heat treating tubular devices
A method of heat treating a tubular device may include heat treating a first longitudinal section of the tubular device to have a first austenitic finish temperature and heat treating a second longitudinal section of the tubular device to have a second austenitic finish temperature different than the first austenitic finish temperature. The tubular device may include a hypotube and/or a wire.
US08866046B2 Energization heating method and energization heating device
Provided is a technique in which blanks in different shapes are uniformly healed using energization healing. An energization heating process (S1) is a method for heating a blank (1) by connecting a pair of electrodes (10, 10) to two different end parts of the blank (1) so as to energize the electrode pair (10, 10), wherein the blank (1) is provided with void parts (cutouts (4, 4), a hole (5)) provided in a direction approximately perpendicular to the equipotential line generated between the electrode pair (10, 10), and current passages (current paths (20, 20)) are arranged in the direction approximately perpendicular to the equipotential line generated between the electrode pair (10, 10) within the regions spaced by the void parts (4, 4, 5) in the blank (1). The cutouts (4, 4) are formed with the end parts of the blank (1) as open parts, the hole (5) is provided to the inside of the blank (1), and the reverse side of the side on which the current paths (20, 20) arranged in the cutouts (4, 4) are connected to the blank (1) is connected to the electrodes (10, 10).
US08866045B2 Welder with intelligent battery charger
A system, in one embodiment, may include a portable welder having a welding output, a charging output, a welding circuit coupled to the welding output; and a charging circuit coupled to the charging output. The charging circuit may be configured to automatically adjust power to the charging output based on a feedback associated with charging a battery.
US08866041B2 Apparatus and method of manufacturing laser diode unit utilizing submount bar
A manufacturing method of laser diode unit of the present invention includes steps: placing a laser diode on top of a solder member formed on a mounting surface of a submount, applying a pressing load to the laser diode and pressing the laser diode against the solder member, next, melting the solder member by heating the solder member at a temperature higher than a melting point of the solder member while the pressing load is being applied, and thereafter, bonding the laser diode to the submount by cooling and solidifying the solder member, thereafter, removing the pressing load, and softening the solidified solder member by heating the solder member at a temperature lower than the melting point of the solder member after the pressing load has been removed, and thereafter cooling and re-solidifying the solder member.
US08866040B2 Spatter removing device for laser welder
A spatter removing device for a laser welder including an optic head to which a laser beam is transferred through an optic fiber from a laser oscillator, a cross jet mounted at one side of a lower end portion of the optic head, a safety cover provided at the outside of the optic head so as to surround the optic head, and a material injection unit that injects a material to be welded below the optic head, the device includes a discharge unit and a spatter cooling device. The discharge unit is provided with a discharge pipe that discharges a welding gas and the spatter at one side portion of the safety cover. The spatter cooling device is connected to the discharge pipe and cools the spatter so that the spatter is forcibly collected.
US08866035B2 Triaxial driving device for an electrodischarge machine tool
A triaxial driving device for electrodischarge machine tools having a three-liners-axes mechanism and an electrode tool and has a connecting mount, a first axial rotator, a base, a supporting arm, a second axial rotator, a third axial rotator and an electrode holder. The connecting mount is connected securely to the three-liners-axes mechanism. The first axial rotator is mounted in the connecting mount and has a rotating head. The base is connected securely to the rotating head of the first axial rotator and has a space. The supporting arm is rotatably mounted in the space of the base and has a connecting frame. The second axial rotator is securely connected to the base and the supporting arm and has a rotating head. The third axial rotator is connected to the supporting arm and has a rotating head. The electrode holder is connected to the third axial rotator and the electrode tool.
US08866031B2 Slim keypad structure and electronic device using the same
A slim key includes a supporting plate, at least one key cap, at least one dome and a light-permeable circuit board. The supporting plate is disposed above the circuit board and has at least one frame part. Each frame part is formed with a light-permeable hole at a central portion thereof. The key pad is disposed on the top surface of the frame part correspondingly. The circuit board has at least one conductive circuit formed thereon under the dome correspondingly. The dome is correspondingly disposed between the frame part and the circuit board. According to one embodiment, the instant disclosure also provides an electronic device with the slim keypad structure.
US08866030B2 Keyboard mounting apparatus
A mounting apparatus secures a keyboard to a base. The keyboard defines a plurality of nicks. The base comprises a supporting member and a receiving member installed on the supporting member. A plurality of resilient pieces is located on the supporting member. The receiving member defines a plurality of through holes allowing the resilient pieces to extend through. Each of the resilient pieces is elastically deformable to be over the keyboard to engage in each of the nicks.
US08866029B2 Link apparatus, weighing apparatus using a link apparatus, packaging apparatus using a link apparatus and weighing and packaging system using a link apparatus
A link apparatus supplies objects discharged from a weighing machine to package bags being conveyed successively at a high speed and comprises plural hopper groups each including n hoppers; and plural arms configured to convey an associated hopper group along a revolving path including a first area where the objects are supplied to the hopper group and a second area under which package bags are conveyed successively. The arms convey the hopper groups from the first area to the second area in a predetermined order, the n hoppers sequentially conveyed to the second area are located above the n package bags conveyed to a region under the second area; the hoppers are located above the package bags in the second area, and the hopper groups are stopped in the first area. The hopper groups discharge the objects, when the hopper groups are conveyed in the second area.
US08866026B2 Construction of reliable stacked via in electronic substrates—vertical stiffness control method
A stacked via structure for reducing vertical stiffness includes: a plurality of stacked vias, each via disposed on a disc-like structure. The disc-like structure includes a platted through hole landing with a thickness of substantially 3 μm. The platted through hole landing includes an etched pattern and a copper top surface.
US08866022B2 Printed wiring board, build-up multi-layer board, and production method therefor
A multi-layer printed-wiring-board is used in densely packaging electronic components such as semiconductors having improved function, and a production method therefor, and more specifically it achieves a multi-layer printed-wiring-board having excellent copper-foil-peel-strength and high connection-reliability in which occurrence of structural defects such as delamination (interlayer peeling) is prevented, and a production method therefor. Because of thinning of the printed-wiring-board or diversification of insulating layers constituting the printed-wiring-board, peeling such as delamination may occur between the insulating layers or in an interface between the insulating layer and the plated conductor. By providing pores in substantially the same plane as wiring patterns in the printed-wiring-board including insulating layers, wiring pattern layers made of copper foil alternately laminated on the insulating layers, and pores provided between the wiring patterns, a printed-wiring-board having high connection reliability free from delamination or cracks during heating or in heat cycle conditions.
US08866021B2 Circuit board and process for producing the same
The invention includes: applying an anisotropic conductive resin including conductive particles only to a plurality of bumps of an electronic component; placing the electronic component above a main surface of a flexible wiring board via the anisotropic conductive resin; and pressurizing the electronic component to the wiring board and curing the anisotropic conductive resin applied to the plurality of bumps to join the plurality of bumps to the electrodes of the wiring board. This can prevent a defective mounting of the electronic component.
US08866016B2 Crosslinkable polymer composition
A Polymer Composition comprising at least one unsaturated polymer, and optionally a crosslinking agent.
US08866013B2 Terminal box
A terminal box includes: a main body (101); at least one pair of terminal strips (106) which are connectable to a positive electrode and a negative electrode of a solar cell module; and a backflow prevention diode (118) bridged between the terminal strips (106) to connect the terminal strips (106). The terminal strip (106) and the backflow prevention diode (118) are contained in the main body (101). The terminal strip (106) includes: a supporting part (S) for supporting a lead wire (118a) of the backflow prevention diode (118) in a mounted state; a pinching part (K) for supporting the lead wire (118a) in a pinched state; and a recess (119B) which is provided between the supporting part (S) and the pinching part (K) and configured to position a connecting solder upon connecting the lead wire (118a) and the terminal strip (106).
US08866009B2 Ordered supramolecular system for organic photovoltaics
A structure having: a molecule of carboxymethyl amylose (CMA) in a super-helical conformation; cyanine molecules on the exterior surface of the CMA arranged in a J-aggregate formation; and a chromophore molecule in the interior space of the CMA.
US08866008B2 Transparent glass pane provided with a surface structure
A method of manufacturing a transparent pane, in particular a glass pane, which includes on at least one of its main surfaces a surface structure including an assembly of specified individual motifs in relief, in particular pyramids, cones, or truncated cones, created by embossing or by rolling. A structure is created on the surface of the pane constituted by individual motifs, based on one or more basic motifs but which are distinguished from each other by their depth, their height, and/or the perimeter of their base area, and/or by the position of their peak with respect to their base. With this variation, formation of intensity peaks of the reflected light is prevented and at the same time a high quality of light trapping is obtained by panes suitable, for example, for solar applications.
US08866002B1 Through wafer via structures for concentrated photovoltaic cells
In accordance with the present invention, there is provided multiple embodiments of a concentrated photovoltaic (CPV) receiver cell or die. In each embodiment of the present invention, the receiver die includes a multiplicity of through wafer vias or TWV's which are etched therethrough to effectively eliminate the bus bars on the top or front surface of the receiver die, connectors such as bus bars instead being effectively moved to the bottom or back surface of the receiver die. The movement of the connectors to the back surface of the receiver die provides the potential for a greater active surface area on the front surface for solar input.
US08866000B2 Ultra-efficient energy conversion device for converting light to electricity by rectifying surface plasmon polaritons
An ultra-efficient device for converting light into electricity has a dielectric medium for input light propagation, a metallic medium having an array of surface-plasmon-polariton (SPP) resonator cavities formed at nano-scale and distributed in the metallic medium below the dielectric-metal interface, each nano-scale resonator cavity having a hollow interior as a metal cathode in which a metal anode is disposed, another metallic medium electrically coupled to the anode, and another dielectric medium insulating the anode medium from the cathode medium. In each cavity, the cathode is shaped, dimensioned and spaced from the anode so that standing waves of SPP excitations generated by the input light cause quantum field emission of electrons to be rectified as an electrical output. The SPP resonator cavities may be formed in a plurality of diametral sizes corresponding to component light wavelengths to allow full spectrum energy conversion of broadband light input. High energy conversion efficiencies up to a theoretical maximum of 84% can be obtained.
US08865999B2 Thermoelectric converter with projecting cell stack
A thermoelectric converter is formed by a plenum divided into high and low pressure chambers by a partition and includes a stack of series-coupled alkali-metal thermoelectric cells that projects orthogonally from the partition into one of the chambers.
US08865997B2 Thermoelectric material, method for fabricating the same, and thermoelectric module employing the same
The invention provides a thermoelectric material, a method for fabricating the same, and a thermoelectric module employing the same. The thermoelectric material is composed of Zn4Sb(3-x)Rex, wherein 0
US08865991B1 Portable music player
A portable music player for the playback of a digital audio file comprises a memory for storing a plurality of digital audio files; an audio output; a control for setting a desired change in pitch or tempo; and a digital signal processor configured to process a digital audio file and recover an audio signal therefrom, perceptibly alter one of the pitch and the tempo of the audio signal in response to the desired change in pitch or tempo without perceptibly altering the other of the pitch and tempo, and output the altered audio signal to the audio output.
US08865988B2 Cymbal holding structure, cymbal stand having the holding structure, and fastener used in the holding structure
Provided is a cymbal holding structure and a cymbal stand that make it possible to easily perform operations of adjustment of cymbal fastening force and attachment/detachment of a cymbal with one hand without using any tools, reliably prevent the loosening of a fastener, allow a performer to concentrate on his/her performance without anxiety, cause no burden on a cymbal supporting rod and a screw portion of the fastener, have long product life cycles, and maintain smooth operability for a long period of time.
US08865981B1 Maize variety hybrid X13B630
A novel maize variety designated X13B630 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X13B630 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X13B630 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X13B630, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X13B630. This invention further relates to methods for producing maize varieties derived from maize variety X13B630.
US08865977B1 Maize variety hybrid X08A238
A novel maize variety designated X08A238 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X08A238 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X08A238 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X08A238, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X08A238. This invention further relates to methods for producing maize varieties derived from maize variety X08A238.
US08865973B1 Canola line NS6151
A novel canola variety designated NS6151 and seed, plants and plant parts thereof. Methods for producing a canola plant that comprise crossing canola variety NS6151 with another canola plant. Methods for producing a canola plant containing in its genetic material one or more traits introgressed into NS6151 through backcross conversion and/or transformation, and to the canola seed, plant and plant part produced thereby. Hybrid canola seed, plant or plant part produced by crossing the canola variety NS6151 or a locus conversion of NS6151 with another canola variety.
US08865970B2 Induced heterosis related mutations
The present invention provides plant inbred mutant parent lines producing hybrid offspring having at least one heterosis-related phenotype, particularly total yield associated phenotypes, methods for identifying same and hybrid plants produced therefrom. The present invention further discloses heterosis-related genes and provides the corresponding isolated polynucleotides.
US08865969B2 Mutant plant, a method for producing thereof and a method of increasing frequency of a genetic recombination
According to the present invention, a technique of increasing the frequency of genetic recombination in genomic DNA of a plant is established. Such technique comprises: introducing a restriction enzyme gene that can be expressed in a target plant cell into the plant cell and causing the restriction enzyme gene to be transiently expressed so as to induce genetic recombination of genomic DNA; or introducing a promoter and a restriction enzyme gene using the Agrobacterium method so as to induce genetic recombination of genomic DNA.
US08865968B2 Method for down-regulating gene expression in fungi
The present invention concerns methods for controlling fungus infestation via dsRNA mediated gene silencing, whereby the intact fungus cell(s) are contacted with a double-stranded RNA from outside the fungal cell(s) and whereby the double-stranded RNA is taken up by the intact fungal cell(s). In one particular embodiment, the methods of the invention are used to alleviate plants from fungus pests. Alternatively, the methods are used for treating and/or preventing fungal infestation on a substrate or a subject in need of such treatment and/or prevention. Suitable fungal target genes and fragments thereof, dsRNA constructs, recombinant constructs and compositions are disclosed.
US08865966B2 Pentameric CRP-producing transgenic silkworm
Pentameric CRP is produced at a high efficiency by transferring DNA, which encodes monomeric CRP, into a silkworm to thereby construct a transgenic silkworm and then collecting and purifying pentameric CRP that is produced by the transgenic silkworm constructed above.
US08865965B2 Absorbent article with high and low density portions and skin care agent thereon
An absorbent article includes a liquid permeable topsheet (10), a liquid impermeable or water repellent backsheet, and an absorbent member interposed between these sheets. The topsheet (10) is formed of a nonwoven sheet having high density portions (13A) and low density portions (14A). Each high density portion (13A) and each low density portion (14A) are different in density from each other. The high density portions (13A) and the low density portions (14A) are arranged in planar directions of the topsheet (10). The low density portions (14A) have a larger amount of a skin care agent (5) applied thereto than the high density portions (13A).
US08865964B2 Biomaterials, their preparation by electrospinning and their use in the biomedical and surgical field
There is described a new non-woven fabric produced with the electrospinning technique, and the use thereof as new biomaterial for the biomedical and surgical field.
US08865958B2 Process for ethylbenzene production
A method of producing an alkylaromatic by the alkylation of an aromatic with an alkylating agent, such as producing ethylbenzene by an alkylation reaction of benzene, is disclosed. The method includes using an H-beta catalyst to minimize process upsets due to alkylation catalyst deactivation and the resulting catalyst regeneration or replacement. The H-beta catalyst can be used in a preliminary alkylation reactor that is located upstream of the primary alkylation reactor. The H-beta catalyst used in a preliminary alkylation reactor can reduce the deactivation of the catalyst in the primary alkylation reactor.
US08865956B2 Methods for co-production of alkylbenzene and biofuel from natural oils using hydrocracking
Embodiments of methods for the production of linear alkylbenzene and optionally biofuel from a natural oil are provided. A method comprises the step of deoxygenating the natural oils to form paraffins. A first portion of the paraffins is hydrocracked to form a first stream of normal and lightly branched paraffins in the C9 to C14 range and a second stream of isoparaffins. The first stream is dehydrogenated to provide mono-olefins. Then, benzene is alkylated with the mono-olefins under alkylation conditions to provide an alkylation effluent comprising alkylbenzenes and benzene. Thereafter, the alkylbenzenes are isolated to provide the alkylbenzene product. Optionally a second portion of the paraffins and the isoparaffins are processed to form biofuel.
US08865955B2 Process and apparatus for oligomerizing one or more hydrocarbons
One exemplary embodiment is a process for oligomerizing one or more hydrocarbons. The process includes providing a feed including one or more C3 and C4 hydrocarbons to a separation zone, separating a first stream including an effective amount of C3 olefins for oligomerizing, separating a second stream including an effective amount of one or more C4 olefins for oligomerizing, providing at least a portion of the first stream to a first oligomerization zone for producing at least one of a C9 and a C12 hydrocarbon, and providing at least a portion of the second stream to a second oligomerization zone for producing at least one of a C8 and a C12 hydrocarbon.
US08865952B2 Process for producing fluorine-containing alkene
The present invention provides a process for producing fluorine-containing alkene represented by Formula (2): Rf1C(Rf2)=CH2 wherein Rf1 and Rf2 are the same or different, and are F, H, F(CF2)n- wherein n is an integer of 1 to 5, or H(CF2)m- wherein m is an integer of 1 to 5, with the proviso that Rf1 and Rf2 are not simultaneously H, by heating fluorine-containing alkane represented by Formula (1): Rf1CF(Rf2))CH3 wherein Rf1 and Rf2 are as defined above, in a gas phase to perform a dehydrofluorination reaction, the dehydrofluorination reaction being carried out in the presence of 5 mol or more of anhydrous hydrogen fluoride per mol of the fluorine-containing alkane. The process of the present invention can significantly enhance the selectivity of fluorine-containing alkene without reducing conversion in the production of fluorine-containing alkene from fluorine-containing alkane, such as fluorine-containing propane.
US08865951B2 Dual phase catalysts system for mixed olefin hydrations
Processes for producing mixed alcohols from mixed olefins and the catalyst systems for making such alcohols are provided. Additionally, processes for producing fuel compositions having mixed alcohols prepared from mixed olefins are also provided as embodiments of the present invention. The catalyst systems include a dual phase catalyst system that includes a water soluble acid catalyst and a solid acid catalyst.
US08865946B2 Process for producing fluoromethyl hexafluoroisopropyl ether
There is provided according to the present invention a process for producing fluoromethyl hexafluoroisopropyl ether ((CF3)2CH—O—CH2F), including: reacting bisfluoromethyl ether with hexafluoroisopropyl alcohol in a solvent substantially immiscible with hydrogen fluoride in the presence of a catalytic amount of a strong acid selected from sulfuric acid and any other acids stronger in acidity than sulfuric acid. The process of the present invention enables industrial production of the fluoromethyl hexafluoroisopropyl ether without using hydrogen fluoride or a large amount of sulfuric acid and thereby without causing a large amount of waste as a by-product.
US08865944B2 Process for the purification of polyol PFPE derivatives
A process for purifying a polyol (per)fluoropolyether derivative [polyol (P)] from a mixture of hydroxyl (per)fluoropolyether derivatives [mixture (M)]. Such polyol (P) comprising one or more hydroxyl (per)fluoropolyether derivatives [PFPE (OH)] comprising at least one (per)fluoropolyoxyalkylene chain (chain Rf) and at least one end-group having formula (t3) —CF2CH2OCH2CH(OH)CH2OCH2CH(OH)CH2OH. Such mixture (M) comprising the polyol (P) and at least one PFPE (OH) different from the polyol (P) and comprising at least one chain Rf and at least one end-group selected from end-groups having formula (t1) —CF2CH2OH and formula (t2) —CF2CH2OCH2CH(OH)CH2OH. The process comprises the steps of: 1) reacting the mixture (M) with a ketone, an aldehyde or a combination thereof to yield corresponding mixture of cyclic ketal/acetal (per)fluoropolyether derivatives [PFPEs (OH)p] [protected mixture (P)]; 2) carrying out a molecular distillation of the protected mixture (P) to isolate a protected product heavy residue [product (Pr)]; 3) hydrolyzing the product (Pr) to yield deprotected product [product (Pd)]; and 4) carrying out a distillation under reduced pressure of the product (Pd) to obtain polyol (P).
US08865943B2 Catalytic conversion of alcohols and aldehydes
The invention provides a process for preparing higher alcohols and/or aldehydes and also mixtures thereof by catalytic reaction of ethanol, the reaction taking place in the presence of at least one catalyst, the catalyst comprising an activated-carbon substrate which is provided with at least one metal, and more particularly has at least one metal dope.
US08865939B2 Method for producing trans-1,4-bis(aminomethyl) cyclohexane
A method for producing trans-1,4-bis(aminomethyl)cyclohexane includes a nuclear hydrogenation step of producing a hydrogenated terephthalic acid or terephthalic acid derivative by nuclear hydrogenation of a terephthalic acid or terephthalic acid derivative, the terephthalic acid or terephthalic acid derivative being at least one selected from the group consisting of terephthalic acid, terephthalic acid ester, and terephthalic acid amide; a cyanation step of treating the hydrogenated terephthalic acid or terephthalic acid derivative with ammonia, thereby producing 1,4-dicyanocyclohexane, and producing trans-1,4-dicyanocyclohexane from the obtained 1,4-dicyanocyclohexane; and an aminomethylation step of treating the trans-1,4-dicyanocyclohexane with hydrogen, thereby producing trans-1,4-bis(aminomethyl)cyclohexane. Metal oxide is used as a catalyst in the cyanation step, and the obtained trans-1,4-dicyanocyclohexane has a metal content of 3000 ppm or less.
US08865936B2 Vegetal oil derivatives
This invention comprises the use of the interesterification reaction between vegetal or animal oils and esters from monoacids (preferentially with 1 to 12 carbons) and monoalcohols (preferentially with 1 to 12 carbons). The use of ethyl acetate is preferred as it is a product that may be obtained from ethanol (renewable) and has a boiling point (77° C.), which facilitates separation by vacuum distillation at the end of the reaction and its reuse. By varying the molar ratio between glycerol triester (oil or fat) and monoalcohol ester, different proportions of glycerol esters are obtained with 1 or 2 linked fatty acids and 1 or 2 linked acids of short chain, along with the formation of fatty acid ester of monoalcohol. After the distillation of excess residual ethyl acetate, products are obtained with viscosity from 21 to 33 cPs at 25° C., in the case of the reaction with soy oil.
US08865934B2 Method for preparing ramalin
The present invention relates to a method for synthesizing ramalin, and more particularly to a method for synthesizing ramalin, which comprises allowing 2-hydrazinylphenol to react with L-glutamic acid having a protected carboxyl group at C-1 and a protected amino group at C-2, and a method for preventing decomposition of the ramalin. According to the present invention, ramalin having excellent antioxidant and anti-inflammatory activities can be synthesized in high yield, and thus can be produced in large amounts. In addition, ramalin can be stably maintained for a long period of time, and thus can be easily used for industrial purposes.
US08865932B2 Fluorinated graphene oxide and preparation method thereof
Provided are a fluorinated graphene oxide and a preparation method thereof. In the fluorinated graphene oxide, the mass percent of fluorine is 0.5%
US08865929B2 Reactive dyes for contact lenses
A method for preparing a polymerizable monomer-dye compound is provided in which a monomer, a reactive dye, and base are combined under substantially anhydrous reaction conditions to form the polymerizable monomer-dye compound, wherein the monomer comprises a pendant reactive group that covalently links to the reactive dye to form the monomer-dye compound.
US08865928B2 Process for removing dioxane from a composition
Apparatus and processes for removing dioxane from a composition, e.g., an ethoxylated fatty alcohol sulfate paste, utilize an evaporator having an inlet chamber and one or more heated channels. The process includes the step of heating the composition at a location upstream of the flow restriction to a temperature above the flashing temperature of water at a pressure of the channel inlet and applying a pressure to the heated composition to avoid such flashing. The process further includes the step of passing the pressurized, heated composition through the evaporator. The process can further include injecting a vapor into the channel. The purified, concentrated product can be diluted with water to a desired concentration.
US08865925B2 Method for manufacturing hydrophilic silicone macromer
A method for manufacturing a hydrophilic silicone macromer is provided. A hydrosilylation between a Si—H bond of a polysiloxane and a C═C bond of a hydrophilic monomer is performed by using a rhodium-containing catalyst to form the polysiloxane having a hydrophilic side chain having an amide group or a phosphoryl choline group. After performing an end-capping reaction, the hydrophilic silicone macromer is formed.
US08865920B2 N-acylation of amines
Provided herein are processes for the preparation of N-acylated amines. In particular, the processes comprise contacting an amine with an acid comprising a carboxylic acid group to form the N-acylated amine.
US08865917B2 Hardeners for thermosettable resin compositions
A multifunctional aromatic amine hardener composition including the reaction condensation product of (a) at least one aniline and (b) at least one non-aromatic cyclic dicarboxaldehyde; and a reactive thermosettable resin composition including (i) at least one multifunctional aromatic amine hardener composition curing agent, (ii) at least one thermoset resin, and optionally (c) at least one catalyst; and a process for preparing a thermoset product from the thermosettable composition. The hardener composition above and a thermoset resin may be used to prepare a thermoset product with improved thermo-mechanical behavior.
US08865916B2 Functionalized diamond nanoparticles
A diamond nanoparticle can be functionalized with a substituted dienophile under ambient conditions, and in the absence of catalysts or additional reagents. The functionalization is thought to proceed through an addition reaction.
US08865913B2 Crystalline forms and processes for their preparation
The present invention relates to crystalline Form A of 1-[(3R)-6,8-difluoro-3,4-dihydro-2H-1-benzopyran-3-yl]-1,3-dihydro-5-[2-[(phenylmethyl)amino]ethyl]-2H-imidazole-2-thione and crystalline Form B of 1-[(3R)-6,8-difluoro-3,4-dihydro-2H-1-benzopyran-3-yl]-1,3-dihydro-5-[2-[(phenylmethyl)amino]ethyl]-2H-imidazole-2-thione, processes for preparing the forms and their uses in medicine. The present invention also relates to the amorphous form of 1-[(3R)-6,8-difluoro-3,4-dihydro-2H-1-benzopyran-3-yl]-1,3-dihydro-5-[2-[(phenylmethyl)amino]ethyl]-2H-imidazole-2-thione processes for preparing it and its uses in medicine.
US08865912B2 Benzimidazole derivatives as PI3 kinase inhibitors
This invention relates to the use of benzimidazole derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide 3′ OH kinase family (hereinafter PI3 kinases), suitably, PI3Kα, PI3Kδ, PI3Kβ, and/or PI3Kγ. Suitably, the present invention relates to the use of benzimidazoles in the treatment of one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries. More suitably, the present invention relates to PI3Kβ selective benzimidazoles compounds for treating cancer.
US08865909B2 Anti-biofilm agents
Novel agents exhibiting anti-biofilm formation activity while being non-cytotoxic are provided, as well as methods of using the same, either per se or conjugated to a polymer, for preventing and/or reducing the formation of microbial biofilms and/or for disrupting microbial biofilms. The novel agents described herein include thiazolidine-2,4-diones (TZDs), pyrrolidine-2,5-diones (PYDs), imidazolidine-2,4-diones or oxazolidine-2,4-diones, substituted by an alkyl having 7-20 carbon atoms in its backbone chain.
US08865908B2 Process for the preparation of a 2-pyridylethylcarboxamide derivative
Process for the preparation of a N-[2-(2-pyridinyl)ethyl]carboxamide derivative of general formula (I) or a salt thereof Intermediate of general formula (II) Intermediate of general formula (III)
US08865905B2 Organic compounds
A compound of formula IV: wherein R1, R2, and R3 are, independently at each occurrence, a C1-C20 aliphatic radical, a C3-C20 aromatic radical, or a C3-C20 cycloaliphatic radical; Ar is heteroaryl, aryl, alkyl or cycloalkyl; b and c are, independently at each occurrence, an integer ranging from 0-4; a is an integer ranging from 0-3; and n is an integer ranging from 2 to 4.
US08865903B2 Continuous process for the alkylation of cyclic tertiary amines
A continuous process for the alkylation of tertiary amines and, in particular, to a continuous process for the quaternization of cyclic tertiary amines useful for the preparation of cyclic quaternary ammonium salts with high purity is described.
US08865902B2 Deuterated CFTR potentiators
This invention relates to compounds of Formula I: and pharmaceutically acceptable salts thereof. This invention also provides compositions comprising a compound of this invention and the use of such compositions in methods of treating diseases and conditions that are beneficially treated by administering a CFTR potentiator.
US08865900B2 Methyltetrazole sulfides and sulfones
The present invention relates to a process for the preparation of a 1-methyl-1H-tetrazole-5-thio derivative comprising reaction of a halomethyl substrate with 1-methyl-H-tetrazole-5-thiol to obtain a thio-ether compound, and oxidizing the thio-ether compound to the corresponding sulfone. In case of a chiral halomethyl substrate, the resulting chiral diol sulfone derivative is suitable as a building block for statin type compounds.
US08865898B2 Nucleoside analog or salt thereof, oligonucleotide analog, gene expression inhibitor, and nucleic-acid probe for detecting gene
A nucleoside analog and a salt thereof represented by any of the general formulae (1) to (10) below: wherein R1, R2, and R3 are the same or different groups, and each of the R1, R2 and R3 is selected from a hydrogen atom, a protecting group for a functional group in nucleic acid synthesis, a phosphate group, a phosphate group protected by a protecting group in nucleic acid synthesis, and an activated phosphate group for solid phase synthesis; and Ar is one of an aromatic hydrocarbon group and a polyaromatic hydrocarbon group.
US08865891B2 Optically-detectable enzyme substrates and their method of use
The present invention relates to compounds that are substrates for an enzyme, and upon reaction with the enzyme provide a detectable response, such as an optically detectable response. In particular, the compounds have utility in detecting the presence of a β-lactamase in a sample. In addition to the compounds, methods are disclosed for analyzing a sample for the presence of a β-lactamase, for example, as an indicator of expression of a nucleic acid sequence including a sequence coding for a β-lactamase. Kits are disclosed that include the disclosed compounds and additional components, for example, cells, antibodies, a β-lactamase or instructions for using the components in an assay.
US08865889B2 Methods for preparing alkali cellulose and cellulose ether
The invention is a method for efficiently preparing alkali cellulose having a uniform alkali distribution therein. More specifically, the invention is a method for preparing alkali cellulose comprising steps of bringing pulp into continuous contact with an alkali metal hydroxide solution in a rotary feeder type contactor to generate a contact mixture, and draining the contact mixture; and a method for preparing cellulose ether comprising use of the alkali cellulose thus prepared; an apparatus for preparing alkali cellulose, comprising a rotary feeder comprising a cyclic housing comprising an inlet port and an outlet port, a cyclic contact drum being circularly rotatable along the housing in the housing and comprising a plurality of filter cells arranged in a circumferential direction, and a filtrate-discharging tube being disposed in a diameter direction inside of the cyclic contact drum and collecting the filtrate which has passed the filter, and a drainer for draining a cake discharged from the contactor.
US08865887B2 Method for synthesizing calixarene and/or cyclodextrin copolymers, terpolymers and tetrapolymers, and uses thereof
The present invention relates to a novel method for synthesizing a composition of polymers, copolymers, terpolymers and tetrapolymers, and to the use thereof, said composition being made from: cyclodextrins, in particular α-cyclodextrin, β-cyclodextrin, γ-cyclodextrin, the derivatives or corresponding mixtures thereof, and/or calix[n]arene(s) and/or of calix[n]arene derivative(s) and/or a mixture of two or more different calix[n]arenes selected from calix[n]arenes (n=4-20) and/or the derivatives thereof, and to the uses thereof. A method was developed on the basis of direct-melt polycondensation. The invention can be used in the pharmaceutical, human medicine, veterinary medicine, chemistry, separation chemistry, environmental, electronics, biological, diagnostics, phytosanitation, medicinal food, agri-food, and cosmetics fields, and in the nutraceutical field and in the field of molecular imprints (MIP).
US08865884B2 Antisense modulation of kinesin-like 1 expression
Antisense compounds, compositions and methods are provided for modulating the expression of kinesin-like 1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding kinesin-like 1. Methods of using these compounds for modulation of kinesin-like 1 expression and for treatment of diseases associated with expression of kinesin-like 1 are provided.
US08865881B2 Delivery of proteins using adeno-associated virus (AAV) vectors
Disclosed herein are compositions, systems and methods for delivery of proteins of interest using adeno-associated virus (AAV) vectors.
US08865880B2 Identification of a novel BHD gene
The present disclosure relates to Birt-Hogg-Dubé syndrome, nucleic acids encoding the BHD gene, and methods of using the nucleic acids and proteins encoded thereby. In particular, the present disclosure relates to methods of diagnosing BHD disease and related conditions, such as spontaneous pneumothorax and kidney cancer, and methods of treating BHD skin lesions.
US08865870B2 Anti-CXCR3 antibodies and methods of use thereof
The present disclosure provides anti-CXCR3 antibodies and methods of using the antibodies to diagnose and/or treat CXCR3-associated disorders such as diabetes mellitus type I (T1D), particularly new-onset T1D. In certain embodiments, disclosed herein are CXCR3 neutralizing antibodies.
US08865868B2 Conjugated proteins with prolonged in vivo efficacy
The invention relates to conjugated proteins, in particular but not exclusively, blood coagulation factors, to processes for preparing the conjugated proteins which contain the steps of reacting a protein or glycoprotein, such as factor VIIa or human growth hormone, with a water insoluble albumin binder in the presence of an optionally substituted cyclodextrin molecule, to pharmaceutical compositions comprising the protein conjugates and to the use of the protein conjugates in therapy, in particular but not exclusively, for the treatment of diseases alleviated by blood coagulation factors such as the prophylactic treatment of hemophilia.
US08865866B2 Diphtheria toxin variant
The present invention relates to methods and compositions of modified variants of diphtheria toxin (DT) that reduce binding to vascular endothelium or vascular endothelial cells, and therefore, reduce the incidence of Vascular Leak Syndrome. One aspect of the present invention relates to a polypeptide toxophore from a modified DT, wherein the mutation is the substitution or deletion at least one amino acid residue at the amino acid residues 6-8, 28-30 or 289-291 of native DT. Another aspect of the present invention relates to a fusion protein which comprises a modified DT and a non-DT fragment. Another aspect of the present invention relates to the use of modified DT for the treatment of cancer.
US08865864B2 Mutant epidermal growth factor polypeptides with improved biological activity and methods of their making and use
Compositions that are EGF polypeptides that possess improved biological activity as compared to the biological activity exhibited by wild-type EGF are provided. Also provided are methods for the preparation of these mutants, methods for the use of these mutants, methods for rationally designing new polypeptide mutants, and methods for screening mutants polypeptides to identify novel EGF mutants with desirable biological activities.
US08865860B2 Electron donating polymer and solar cell including the same
An electron donating polymer including moiety A represented by Chemical Formula 1, and a solar cell including the electron donating polymer are provided. In Chemical Formula 1, X1 is a functional group including at least two ester residual groups and a substituted or unsubstituted divalent aliphatic organic group linking the ester residual groups, and X2 is one of hydrogen, a halogen atom, a substituted or unsubstituted C1 to C20 aliphatic group, a hydroxy group, a substituted or unsubstituted C1 to C20 alkoxy group, a substituted or unsubstituted C1 to C30 ketone group, a substituted or unsubstituted C1 to C20 ester group, a thiol group, —SR100 (wherein R100 is one of a substituted or unsubstituted C1 to C20 aliphatic group, a substituted or unsubstituted C2 to C30 aromatic group, and a substituted or unsubstituted C2 to C30 heterocycloalkyl group), and a combination thereof.
US08865856B2 Toner resins for electronic copying purposes
A polycarbonate of number average molecular weight from 500 to 10000, glass transition point from 30 to 80° C. and hydroxyl group value of 30 mg KOH/g or less. The use of the polycarbonate in a urethane modified resin used as an ingredient for the production of a toner or a developer. A urethane modified resin obtained by reacting a polymer mixture containing the polycarbonate and a polycondensed resin of glass transition point from 10 to 60° C. and hydroxyl group value from 20 to 100 mg KOH/g with a polyfunctional isocyanate compound wherein the ratio of polycarbonate to polycondensed resin is from 20:80 to 80:20 by weight and the molar ratio of isocyanate groups in the polyisocyanate compound to hydroxyl groups in the polymer mixture is from 0.4 to 1.2:1. A toner for electronic copying containing the urethane modified polycarbonate based resin. A developer containing the toner and optionally a carrier.
US08865855B2 Polycarbonate copolymer and method of producing the same
The problem to be solved by the present invention is to provide a polycarbonate copolymer containing a plant-derived raw material, which is excellent in the mechanical strength and heat-resistant and assured of small refractive index, large Abbe number, small birefringence and excellent transparency. The present invention provides a polycarbonate copolymer containing a constitutional unit derived from a dihydroxy compound represented by the following formula (1) and a constitutional unit derived from an alicyclic dihydroxy compound, wherein the Abbe number is 50 or more and the 5% thermal reduction temperature is 340° C. or more; and a method of producing this polycarbonate copolymer by reacting a dihydroxy compound represented by the following formula (1) and an alicyclic hydroxy compound with a carbonic acid diester in the presence of a polymerization catalyst.
US08865854B2 Method of synthesizing tuneably high functionality in high molecular weight natural oil polyols
Methods of one-pot synthesis of high molecular weight natural oil polyols having a functionality of between about 4 and about 8 are provided. The resultant polyols may be directly reacted with polyisocyanates to produce polyurethanes.
US08865852B2 Siloxane-based low dielectric constant thin films using cyclo-siloxane and a method for preparing the same
A low-dielectric constant thin film prepared from a silsesquioxane polymer matrix as a precursor and a method for preparing the same which comprises preparing silsesquioxane sol by adding a stereoisomer of a multi reactive cyclosiloxane to an alkoxysilane are provided. The low-dielectric-constant thin film retains a stable film state even at a curing temperature of −500° C. without being decomposed, a very uniform surface property with a low surface modulus, and a superior coatability as to be coatable smoothly with no crack even with a thickness of 500 nm or larger.
US08865851B2 Moisture-curing coating compositions comprising aprotic solvents and binders having alkoxysilane groups and method of forming a multicoat finish therewith
Disclosed is a moisture-curing coating composition based on aprotic solvents comprising a binder with a polyacrylate or polymethacrylate obtained using monomer (I) and a phosphorous- and nitrogen-containing catalyst. Also disclosed is a method of producing a multicoat finish using these coating compositions and also to the use of this method to coat interior or exterior bodywork components or to coat components for shipbuilding and aircraft construction or to coat components for household and electrical appliances or to coat plastics moldings or films.
US08865848B2 Process for olefin polymerisation using group 4 metallocene as catalysts
A process for the preparation of a random propylene copolymer comprising polymerizing propylene and at least one C2-10 alpha olefin (especially ethylene) in the presence of a catalyst; wherein said catalyst comprises: (i) a complex of formula (I): wherein M is zirconium or hafnium; each X is a sigma ligand; L is a divalent bridge selected from —R′2C—, —R′2C—CR′2—, —R′2Si—, —R′2Si—SiR2—, —R′2Ge—, wherein each R′ is independently a hydrogen atom, C1-C20-hydrocarbyl, tri(C1-C20-alkyl)silyl, C6-C20-aryl, C7-C20-arylalkyl or C7-C20-alkylaryl; each R1 is a C4-C20 hydrocarbyl radical branched at the β-atom to the cyclopentadienyl ring, optionally containing one or more heteroatoms belonging to groups 14-16, or is a C3-C20 hydrocarbyl radical branched at the β-atom to the cyclopentadienyl ring where the β-atom is an Si-atom; n is 0-3; each R18 is the same or different and may be a C1-C20 hydrocarbyl radical optionally containing one or more heteroatoms belonging to groups 14-16; each R4 is a hydrogen atom or a C1-6-hydrocarbyl radical; each W is a 5 or 6 membered aryl or heteroaryl ring wherein each atom of said ring is optionally substituted with an R5 group; each R5 is the same or different and is a C1-C20 hydrocarbyl radical optionally containing one or more heteroatoms belonging to groups 14-16; and optionally two adjacent R5 groups taken together can form a further mono or multicyclic ring condensed to W optionally substituted by one or two groups R5; and (ii) a cocatalyst comprising an organometallic compound of a Group 13 metal.
US08865834B2 Adhesive polymer composition
A novel adhesive composition suitable for composing multilayered coatings onto large, industrial equipment such as pipeline tubes is devised. The composition is a blend based on a polyethylene which determines the blend's favorable properties, which polyethylene itself can be used further in coating cables and for producing moldings, especially rotomoulded articles.
US08865833B2 Polycarbonate composition comprising nanomaterials
A method of preparing a polycarbonate nanocomposite comprising forming a reactant mixture comprising a nanomaterial, a solvent, a dihydroxy compound and an activated carbonate; and polymerizing the dihydroxy compound and the activated carbonate in the presence of the solvent to form the polycarbonate nanocomposite is disclosed. Also disclosed are polycarbonate nanocomposites prepared in accordance with this method, and thermoplastic compositions comprising the polycarbonate nanocomposites. Also disclosed are polycarbonate compositions comprising the nanomaterial.
US08865826B2 Organic/inorganic composite film and method for forming the same
The present invention provides an organic/inorganic composite film, which includes a poly(vinylidene fluoride) (PVDF) and inorganic nano-platelets dispersed therein. A weight ratio of the PVDF and the inorganic nano-platelets is between about 97:3 and 20:80. The inorganic nano-platelets have a particle size of about 20-80 nm, wherein the organic/inorganic composite film has a transparency of greater than about 85% at a wavelength between 380 and 780 nm. In addition, a method for forming the organic/inorganic composite film is also provided.
US08865822B2 Hot melt adhesive compositions having good adhesion on both polar and nonpolar substrates
A hot melt adhesive composition including a) at least one thermoplastic silane grafted poly-α-olefin that is solid at 25° C.; and b) at least one reaction product of a polyisocyanate having an isocyanate-reactive silane, wherein the isocyanate-reactive silane includes exactly one group reactive to an isocyanate group, selected from a hydroxyl group, a mercapto group, and an amino group, and wherein the reaction product includes a molecular weight Mw of less than 1500 g/mol.
US08865821B2 Polyamide moulding composition and use thereof
A thermoplastic molding composition, in particular a polyamide molding composition, consisting of, by weight: (A) 20-88%—thermoplastic material; (B) 10-60%—fibrous fillers, formed from (B1) 10-60%—glass fibers, selected from: glass fibers (B1_1) with a non-circular cross section, wherein the axis ratio of the main cross-sectional axis to the secondary cross-sectional axis is at least 2; high-strength glass fibers (B1_2) with a glass composition (substantially SiO2, AlO, and MgO; or mixtures thereof; (B2) 0-20%—glass fibers, different from glass fibers of component (B1) and have a circular cross section; and (B3) 0-20%—further fibrous fillers, different from fibers of (B1) and (B2), not based on glass, and selected from the group: carbon fibers, graphite fibers, aramid fibers, nanotubes; (C) 2-10%—LDS additive or a mixture of LDS additives; (D) 0-30%—particulate filler; (E) 0-2%—further, different additives; the sum of (A)-(E) is 100% by weight.
US08865817B2 Rapidly curing compound having good adhesive properties
A curable compound is provided, which can be obtained as a mixture of at least two components to be stored separately, of which one component includes a silane-modified polymer and the component of a second component includes an acid or basic salt containing water of crystallization. An aminic adhesion promoter is contained in one or both components or a further component, with the stipulation that no component contains all three substances. Additionally, a method is provided for accelerating the curing of a silane-modified polymer, in which an acid or basic salt containing water of crystallization is added to the silane-modified polymer.
US08865814B2 Rubber composition for tread, and pneumatic tire
Provided are a rubber composition for a tread, capable of improving the fuel economy and abrasion resistance in a balanced manner while achieving a good appearance and a good cure rate; and a pneumatic tire containing the rubber composition. The present invention relates to a rubber composition for a tread, including: a solution-polymerized styrene-butadiene rubber, carbon black, silica, and polyethylene glycol, wherein a rubber component of the rubber composition contains 60 mass % or more of the solution-polymerized styrene-butadiene rubber based on 100 mass % of the rubber component, and the rubber composition includes, per 100 parts by mass of the rubber component, 10 parts by mass or less of the carbon black, 50 parts by mass or more of the silica, and 0.1 to 3.5 parts by mass of the polyethylene glycol.
US08865807B2 Polyamide resin composition having improved physical properties including thin-wall moldability
A polyamide resin composition comprises (A) about 10 to about 70% by weight of a crystalline polyamide resin, (B) about 10 to about 70% by weight of an amorphous polyamide resin, (C) about 5 to about 30% by weight of an inorganic filler, and (D) about 10 to about 50% by weight of a white pigment. The polyamide resin composition can have good thin-wall moldability, light reflectance, yellowing resistance, impact strength and heat resistance.
US08865805B2 Tribologically modified glass-fiber reinforced polyoxymethylene
The present invention relates to a molding composition, a process for the manufacturing of said molding composition, molded parts obtainable therefrom as well as the use of the molding composition for the manufacturing of molded parts used in the automotive industry, for housings, latches, window winding systems, wiper systems, sun roof systems, seat adjustments, levers, gears, claws, pivot housing or wiper arms.
US08865796B2 Nanoparticles with multiple attached polymer assemblies and use thereof in polymer composites
Methods of synthesizing a binary polymer functionalized nanoparticle are generally provided. In one embodiment, a first anchoring compound is attached to a nanoparticle, and a first plurality of first monomers are polymerized on the first anchoring compound to form a first polymeric chain covalently bonded to the nanoparticle via the first anchoring compound. In another embodiment, a first polymeric chain can be attached to the nanoparticle, where the first polymeric chain has been polymerized prior to attachment to the nanoparticle. Thereafter, a second anchoring compound is attached to the nanoparticle, and a second plurality of second monomers are polymerized on the second anchoring compound to form a second polymeric chain covalently bonded to the nanoparticle via the second anchoring compound. Nanoparticles are also generally provided having multiple polymeric assemblies.
US08865787B2 Photocurable silicone gel composition and application thereof
The present invention relates to a photocurable silicone gel composition includes: (A) an organopolysiloxane having at least one group represented by the following general formula (1): in which R1 and R2 each represent hydrogen or an alkyl group having a carbon number of 1 to 20, in an amount of 100 parts by mass; (B) a mercaptoalkyl group-containing organopolysiloxane in an amount of parts by mass such that the number of moles of the mercaptoalkyl group is 0.01 to 1.0 mole per 1 mole of the group represented by the general formula (1) in the component (A); (C) a photopolymerization initiator in an amount of 0.01 to 20 parts by mass per 100 parts by mass of the component (A); and (D) a hindered amine compound having a group represented by the following general formula (2): in which R3 to R6 each represent hydrogen or an alkyl group having a carbon number of 1 to 20, and R7 represents hydrogen or —CH2—R8 in which R8 represents hydrogen or a monovalent organic group, in an amount of 0.001 to 10 parts by mass per 100 parts by mass of the component (A):
US08865785B2 Polishing pad
A polishing pad capable of maintaining a high level of dimensional stability upon moisture absorption or water absorption and providing high polishing rate includes a polishing layer of a polyurethane foam having fine cells, wherein the polyurethane foam includes a cured product of a reaction of (1) an isocyanate-terminated prepolymer (A) that includes an isocyanate monomer, a high molecular weight polyol (a), and a low molecular weight polyol, (2) an isocyanate-terminated prepolymer (B) that includes a polymerized diisocyanate and a polyethylene glycol with a number average molecular weight of 200 to 1,000, and (3) a chain extender.
US08865782B2 Fire-resistant polyurethane foam
A fire-resistant polyurethane foam is provided. A hydroxyl-containing inorganic fire retardant is premixed with a polyisocyanate and a polyol, respectively, to form two premixtures. Then, the two premixtures are mixed for reaction to form a fire-resistant polyurethane foam. Preferably, a combination of different particle sizes of the fire retardant is employed to maximize the amount of the fire retardant and increase the fire resistance of the foam.
US08865776B2 Use of low molecular weight amino alcohols in ophthalmic compositions
The use of low molecular weight amino alcohols in ophthalmic compositions is described. These compounds have been found to enhance the efficacy of anti-microbial preservatives.
US08865775B2 Anti-inflammatory agent and cancer-preventive agent comprising canolol or prodrug thereof and pharmaceutical, cosmetic and food comprising the same
An anti-inflammatory agent or cancer-preventive agent comprising 4-vinyl-2,6-dimethoxyphenol of the formula (1): or a PD thereof.
US08865772B2 Method for treating skin cancer
A method for treating skin cancer including the steps of applying an isothiocyanate functional surfactant to an area affected by skin cancer, wherein the isothiocyanate functional surfactant comprises at least one isothiocyanate functional group associated with an aliphatic and/or aromatic carbon atom of the isothiocyanate functional surfactant.
US08865768B2 Use of polyunsaturated ketones for the treatment of psoriasis
Psoriasis is a common, chronic, inflammatory skin disorder. This invention provides the use of a compound of formula (I) R—CO—X (Wherein R is a C16-24 unsaturated hydrocarbon group optionally interrupted by α, β, γ, or δ to the carbonyl group by a heteroatom or group of heteroatoms selected from S, O, N, SO, SO2 said hydrocarbon group comprising at least 5 non-conjugated double bonds; and X is an electron withdrawing group) in the manufacture of a medicament for the treatment of psoriasis.
US08865766B2 Ester derivatives of bimatoprost compositions and methods
Provided herein, inter alia, are prodrugs of bimatoprost, methods of using the same and compositions including the same.
US08865764B2 Compounds and methods for the treatment of cancer
The present invention provides organic arsenicals. Many of these compounds have potent in vitro cytotoxic activity against numerous human tumor cell lines, both of solid and hematological origin, as well as against malignant blood cells from patients with leukemia.
US08865756B2 Inhibitors of HCV NS5A
Provided herein are compounds, pharmaceutical compositions and combination therapies for inhibition of hepatitis C.
US08865754B2 Compounds for the treatment of neurodegenerative diseases
Compounds and their pharmaceutically acceptable salts for treatment of synucleinopathies, such as Parkinson's disease and tauopathies.
US08865753B2 Compounds as cannabinoid receptor ligands
The present application relates to thiazolylidene containing compounds of formula (I) wherein R1, R2, R3, R4, L2 and A are as defined in the specification. Compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions are also disclosed.
US08865741B2 Aminoindane compounds and use thereof in treating pain
The present application provides novel aminoindane compounds and methods for preparing and using these compounds. These compounds are useful in treating pain and/or itch in patients by administering one or more of the compounds to a patient. The methods include administering a compound of formula (I) or (II) and a TRPV1 receptor activator. In one embodiment, the TRPV1 receptor activator is lidocaine.
US08865735B2 Solid forms of a pharmaceutically active substance
The present invention provides solid forms of the compound of formula 1 and pharmaceutical uses thereof.
US08865733B2 Medication and treatment for disease
A treatment is described for diseases with symptoms that can include fatigue, muscle aches and spasms, weakness, demylenation, and nerve pain. Diseases can include fibromyalgia, depression, and auto-immune and immuno-suppressive diseases, such as MS. The treatment comprises about 1-10 mg naltrexone, at least about 20 μg vitamin B12, at least about 5 mg vitamin B6, at least about 2 mg coenzyme Q, and preferably at least one ancillary medication selected from the group consisting of diazepam, cyclcobenzaprine, clonazepam, alprazolam, 9-tetrahydrocannibinol, fumarate, caffeine, and combinations thereof. The treatment can be administered orally, and can decrease mental and physical symptoms such as, for example, fatigue, gait problems, visual dysfunction, and pain while improving cognitive skills.
US08865732B2 Heterocyclic compounds and uses thereof
New substituted heterocyclic compounds, compositions containing them, and methods of using them for the inhibition of Raf kinase activity are provided. The new compounds and compositions may be used either alone or in combination with at least one additional agent for the treatment of a Raf kinase mediated disorder, such as cancer.
US08865728B2 Combinations comprising methotrexate and DHODH inhibitors
The present disclosure relates to combinations comprising (a) methotrexate, and (b) a DHODH inhibitor and their uses.
US08865727B2 Method for treating pain syndrome and other disorders
The present invention provides the use of certain compounds to treat peripheral or central pain syndrome and other disorders associated with the T-type calcium ion channels.
US08865719B2 Substituted heterocycles and their use as allosteric modulators of nicotinic and GABAA receptors
The present invention is related to heterocycles represented by a compound of Formula I that are novel allosteric modulators of α7 nAChRs and/or GABAA receptors. The invention also discloses the treatment of disorders that are responsive to enhancement of acetylcholine action on α7 nAChRs and negative allosteric modulation of GABAA receptors in a mammal by administering an effective amount of a compound of Formula I.
US08865711B2 Phenylimidazole derivatives as PDE10A enzyme inhibitors
This invention is directed to compounds, which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula I. The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention also provides a method of treating a subject suffering from a drug addiction comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I.
US08865710B2 Methods of treating proliferative diseases
Provided herein are methods of administering N-(5-tert-butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea, or a pharmaceutically acceptable salt or solvate thereof, to human patients, including a specific patient population. Specifically, dosing, dosing schedules or dosing regimens are provided herein. Methods of treating proliferative diseases or FLT-3 mediated diseases in humans are also provided.
US08865707B2 Cholesteryl ester transfer protein inhibitors
Compounds of Formula (I), including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In the compounds of Formula (I), A1 is a cyclic group, and B is a cyclic group which is attached to the heterocyclic ring directly or through a methylene group.
US08865706B2 Heteroaryl-substituted hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds
The present invention is directed to compounds, tautomers and pharmaceutically acceptable salts of the compounds which are disclosed, wherein the compounds have the structure of Formula I, and the variables R1 and R2 are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.
US08865704B2 Wnt pathway antagonists
The present invention relates to known and novel compounds of formula (I) as herein described and pharmaceutical compositions thereof. The compounds of formula (I) have inhibitory effect on the Wnt pathway and are therefore useful in the preparation of a medicament, in particular for the treatment of cancer.
US08865701B2 Spiropyrrolidine beta-secretase inhibitors for the treatment of alzheimer'S disease
The present invention is directed to spiropyrrolidine compounds of formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.
US08865697B2 Crystalline (6R,7R)-7-{2-(5-amino-[1,2,4] thiadiazol-3-yl)-2-[(Z)-trityloxyimino]-acetylamino}-3-[(R)-1′-tert-butoxycarbonyl-2-oxo-[1,3′]bipyrrolidinyl-(3E)-ylidenemethyl]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid benzhydryl ester; its manufacture and use
A solid DMSO solvate of a compound of formula (I) is described, which is a useful intermediate for preparing the broad spectrum antibiotics Ceftobiprole and Ceftobiprole Medocaril.
US08865695B2 Steroidal compositions
Provided herein are steroid containing compositions suitable for providing therapeutically effective amounts of at least one steroid to individuals. Also provided herein are compositions comprising testosterone and/or testosterone derivatives suitable for providing therapeutically effective and safe amounts of testosterone over periods of time. Further provided are methods of treating andro- and/or testosterone deficiency in individuals by administering to the individuals compositions described herein.
US08865693B2 Prevention of infection
The invention relates to compounds and methods for the prevention and/or treatment of infection after stroke.
US08865692B2 Compositions for the treatment of gastrointestinal inflammation
Provided herein are methods for treating, preventing or alleviating the symptoms of and inflammation associated with inflammatory diseases and conditions of the gastrointestinal tract, for example, those involving the esophagus. Also provided herein are pharmaceutical compositions useful for the methods of the present invention.
US08865685B2 Esters for treatment of ocular inflammatory conditions
The present invention relates to ophthalmic compositions and methods for the treatment of dry eye and other inflammatory ocular conditions. In particular, the present invention relates to a composition comprising an esterified anti-inflammatory lipid mediator, which is an ester of an anti-inflammatory lipid mediator that is a reaction product of the anti-inflammatory lipid mediator and a polyol wherein the majority of the anti-inflammatory lipid mediator is present in an ester form. In this way, the compositions are substantially free of an acid form of the anti-inflammatory lipid mediators. This composition can be topically delivered to the ocular surface via a preparation, solution, gel, ointment, and/or strip and/or a contact lens.
US08865679B2 Use of beta-glucans against biological warfare weapons and pathogens including anthrax
The present invention provides a means to broadly protect the military and the public from injury from biological warfare weapons, particularly infective agents such as anthrax. Beta (1,3)-glucans, particularly whole glucan particles, PGG-Glucan, and microparticulate glucan, provide general immune enhancement, thereby increasing the body's ability to defend against a wide variety of biological threats. Beta (1,3)-glucans have been shown to increase the resistance to infection by anthrax and other infectious organisms when administered before and after infection. The anti-infective mechanism of β(1,3)-glucan appears to involve stimulation of the innate immune system through increased cytokine release and CR3 receptor activation. Beta (1,3)-glucan is pharmaceutically stable, relatively compact, and can also be used without significant side effects. Beta (1,3)-glucan can also enhance the effectiveness of other medical countermeasures such as antibiotics, vaccines, and immune antibodies.
US08865671B2 RNAi-mediated inhibition of spleen tyrosine kinase-related inflammatory conditions
RNA interference is provided for inhibition of spleen tyrosine kinase (Syk) mRNA expression, in particular, for treating patients having a Syk-related inflammatory condition or at risk of developing a Syk-related inflammatory condition such as allergic conjunctivitis, ocular inflammation, dermatitis, rhinitis, asthma, allergy, or mast-cell disease.
US08865670B2 RNAi-related inhibition of TNFα signaling pathway for treatment of glaucoma
RNA interference is provided for inhibition of tumor necrosis factor α (TNFα) by silencing TNFα cell surface receptor TNF receptor-1 (TNFR1) mRNA expression, or by silencing TNFα converting enzyme (TACE/ADAM17) mRNA expression. Silencing such TNFα targets, in particular, is useful for treating patients having a TNFα-related condition or at risk of developing a TNFα-related condition such as the ocular conditions associated with elevated intraocular pressure (IOP), including glaucoma and ocular hypertension.
US08865667B2 Higher-order cellular information processing devices
The invention provides various signal processing devices for integrating two or more biological signals (e.g., the presence, absence or concentration of specific ligands, etc.) to generate a status output, or a response that modulates one or more biological activities based on the status of the biological signals. The various described signal processing/integration mechanisms may be combined with one another to provide the device with more flexibility in integrating high-order cellular information. The signal processing devices of the invention have many uses in various biological systems, including gene expression control or ligand-concentration sensing.
US08865665B2 Aminoglycosides: synthesis and use as antifungals
The present invention relates to novel aminoglycoside analogs having certain substituents at the 6 position of ring III which exhibit improved antifungal activity but possess minimal antibacterial properties. The compounds of the present invention are analogues of kanamycin A. Also provided are methods of synthesizing and methods of using the compounds of the present invention. The compounds of the present invention are useful in treating or preventing fungal disease.
US08865662B2 Macrolides and their use
The invention relates to macrolide compounds of formula (I), the use of said compounds as medicaments, in particular for the treatment or prevention of inflammatory and allergic diseases, pharmaceutical compositions containing said compounds and to processes for their preparation. The invention relates in particular to macrolide compounds with antiinflammatory activity mediated primarily through inhibition of phosphodiesterase 4 (PDE4) which makes them useful for the treatment and/or prevention of inflammatory and allergic diseases such as chronic obstructive pulmonary disease (COPD), asthma, rheumatoid arthritis, atopic dermatitis or inflammatory bowel disease or proliferative diseases such as cancer.
US08865658B2 Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides
Disclosed herein are non-natural amino acids and polypeptides that include at least one non-natural amino acid, and methods for making such non-natural amino acids and polypeptides. The non-natural amino acids, by themselves or as a part of a polypeptide, can include a wide range of possible functionalities, but typical have at least one aromatic amine group. Also disclosed herein are non-natural amino acid polypeptides that are further modified post-translationally, methods for effecting such modifications, and methods for purifying such polypeptides. Typically, the modified non-natural amino acid polypeptides include at least one alkylated amine group. Further disclosed are methods for using such non-natural amino acid polypeptides and modified non-natural amino acid polypeptides, including therapeutic, diagnostic, and other biotechnology uses.
US08865654B2 Eye drops
An eyedrop containing a peptide having an amino acid sequence represented by Ser-Ser-Ser-Arg (“SSSR”), or a pharmacologically acceptable salt thereof; and a peptide having an amino acid sequence represented by Phe-Gly-Leu-Met-NH2 (“FGLM”), or a pharmacologically acceptable salt thereof. The concentration ratio between SSSR or a pharmacologically acceptable salt thereof and FGLM or a pharmacologically acceptable salt thereof is between 1/15 and 1/50. The concentration of SSSR or a pharmacologically acceptable salt thereof is between 0.001% and 0.3% (w/v) and the concentration of FGLM or a pharmacologically acceptable salt thereof is between 0.015% and 1.5% (w/V). The pH of the eye drop is maintained between 2.5 and 6.5.
US08865653B2 Method of treatment for immunogenic treatment resistant cancer
The present invention relates to the fields of genetics, immunology and medicine. The present invention more specifically relates to in vitro or ex vivo methods for determining the susceptibility to a cancer treatment of a subject having a tumor. These methods comprise a step of determining the ability of the treatment, of the subject and/or of the tumor to induce an anticancer immune response, the inability of at least one of the treatment, the subject and the tumor to induce an anticancer immune response being indicative of a resistance of the subject to the therapeutic treatment of cancer. Inventors in particular identify genes specific of a human subject or of cancerous cells which can be used to predict or assess the sensitivity of a subject to a treatment of cancer. The invention also relates to particular compounds capable of activating or enhancing the immune system of a particular subject, when the subject is exposed to a therapeutic treatment of cancer or before such an exposition. It further relates to uses of such compounds, in particular to prepare a pharmaceutical composition to allow or improve the efficiency of a therapy of cancer in a subject in need thereof. The present invention in addition provides kits, methods for selecting a compound of interest, as well as pharmaceutical compositions and uses thereof.
US08865650B2 Therapy for complications of diabetes
A method for enhancing glycemic control and/or insulin sensitivity in a human subject having diabetic nephropathy and/or metabolic syndrome comprises administering to the subject a selective endothelin A (ETA) receptor antagonist in a glycemic control and/or insulin sensitivity enhancing effective amount. A method for treating a complex of comorbidities in an elderly diabetic human subject comprises administering to the subject a selective ETA receptor antagonist in combination or as adjunctive therapy with at least one additional agent that is (i) other than a selective ETA receptor antagonist and (ii) effective in treatment of diabetes and/or at least one of said comorbidities other than hypertension. A therapeutic combination useful in such a method comprises a selective ETA receptor antagonist and at least one antidiabetic, anti-obesity or antidyslipidemic agent other than a selective ETA receptor antagonist.
US08865645B2 Method of treating lung fibrosis using ST2 polypeptide
Methods and compositions for treating fibrosis are disclosed.
US08865644B2 Rapamycin formulation using recombinant high-density lipoprotein including apolipoprotein A-I and a mutant thereof
Provided is a rapamycin formulation using a recombinant high-density lipoprotein including apolipoprotein mutant, the rapamycin formulation in which solubility of rapamycin and medical use, such as aging suppression and arteriosclerosis suppression, are improved by using recombinant high-density lipoprotein including apolipoprotein A-I and its mutant V156K.
US08865641B2 Methods of treatment of fatty liver disease by pharmacological activation of cholinergic pathways
A method of treating a fatty liver disease in a subject. The method comprises administering to the subject an effective amount of a cholinergic pathway stimulating agent, wherein the fatty liver disease is selected from non-alcoholic fatty liver (NAFL), alcoholic fatty liver (AFL), non-alcoholic steatohepatitis (NASH), alcoholic steatohepatitis (ASH), NASH-associated liver fibrosis, ASH-associated liver fibrosis, non-alcoholic cirrhosis, and alcoholic cirrhosis.
US08865636B2 Paint stripping compositions
An environmental safety paint stripping composition comprising dichloroethylene, aromatic alcohols and ethers, surfactants, corrosion inhibitors, thickeners, wax solvents and water. This paint stripping composition is particularly useful in stripping paint and other polymeric coatings from metal substrates such as aluminum and it alloys.
US08865635B1 Aqueous-based cleaning composition with a water-insoluble, fatty alcohol-based builder
An aqueous-based cleaning composition including a water-insoluble builder component and a method of providing both such builder component and such cleaning composition in the absence of heat to provide a cleaning composition which is phase stable at room temperature without loss of cleaning efficacy. The builder component is composed of a C10-C16 linear fatty monohydric alcohol, e.g., tetradecanol, and an alcohol carrier. The alcohol carrier is preferably a C1-C4 monohydric alcohol. An alkyl glucoside is preferably also included in the cleaning composition to enhance the provision of the composition as a clear solution, and to promote combination of hydrophobic and hydrophilic materials upon the mixing of components to provide the cleaning composition.
US08865633B2 Gear oil compositions
A gear oil composition, a method for operating an automotive gear, and a method for improving performance of a gear oil that includes a) a major amount of a base oil having a lubricating viscosity; b) a polysulfide extreme pressure agent; and c) a reaction product of an acylated copolymer and a polyamine.
US08865628B2 Solution for forming rare-earth superconductive film and production method thereof
Provided is a coating solution where, upon producing a rare-earth superconductive composite metal oxide film by means of a coating-pyrolysis method, cracks are not generated in the heat treatment process for eliminating organic components, even when the thickness of the rare-earth superconductive film produced in a single coating is 500 nm or more, and without having to repeat the coating and annealing process. A solution for producing a rare-earth superconductive film which is made into a homogeneous solution by dissolving, in a solvent formed by adding a polyhydric alcohol to a univalent linear alcohol having a carbon number of 1 to 8 and/or water, a metal complex coordinated, relative to metal ions of a metallic species containing rare-earth elements, barium and copper, with pyridine and/or at least one type of tertiary amine, at least one type of carboxylic acid having a carbon number of 1 to 8, and, as needed, an acetylacetonato group.
US08865627B2 Method for manufacturing precursor, method for manufacturing superconducting wire, precursor, and superconducting wire
A method for manufacturing a superconducting wire includes the following steps. A laminate metal having a first metal layer and a Ni layer formed on the first metal layer is prepared. An intermediate layer (20) is formed on the Ni layer of the laminate metal. A superconducting layer (30) is formed on the intermediate layer (20). By subjecting the laminate metal to a heat treatment after at least either of the step of forming a intermediate layer (20) and the step of forming a superconducting layer (30), a nonmagnetic Ni alloy layer (12) is formed from the laminate metal.
US08865625B2 Herbicidal picolinic acid salt composition
A herbicidal concentrate composition comprising a mixture of the monomethylamine and dimethylamine salts of at least one picolinic acid herbicide of formula (Ia): wherein X2 is selected from hydrogen and amino.
US08865624B2 Inhibitor for tobacco axillary bud growth and method for inhibiting tobacco axillary bud growth
The present invention relates to an inhibitor for tobacco axillary bud growth, the inhibitor comprising, as an active ingredient, one or more kinds of very-long chain fatty acid synthesis inhibitors such as a chloroacetamide-based herbicide, fentrazamide, cafenstrole or indanofan; an inhibitor for tobacco axillary bud growth, the inhibitor comprising the aforesaid very-long chain fatty acid synthesis inhibitor together with clorthal-dimethyl or an aliphatic alcohol having 6 to 20 carbon atoms; and a method for inhibiting tobacco axillary bud growth which comprises applying the inhibitor for tobacco axillary bud growth. The inhibitor for tobacco axillary bud growth of the present invention shows sustained drug efficacy at a low concentration, induces neither chemical injury nor disease, and can contribute to the improvement in labor productivity.
US08865623B2 Herbicidally active cyclic diones and derivatives thereof, processes for their preparation, compositions, and method of controlling weeds
Compounds of formula (I), wherein the substituents are as defined in claim 1, are suitable for use as herbicides.
US08865615B2 Ammonia oxidation catalyst, exhaust gas purification device using same, and exhaust gas purification method
Ammonia oxidation catalyst being superior in heat resistance and capable of suppressing by-production of N2O and leakage of ammonia. The ammonia oxidation catalyst (AMOX) removes surplus ammonia, in selectively reducing nitrogen oxides by adding urea or ammonia and using a selective catalytic reduction (SCR) catalyst, into exhaust gas, wherein the ammonia oxidation catalyst is made by coating at least two catalyst layers having a catalyst layer (lower layer) including a catalyst supported a noble metal element on a composite oxide (A) having titania and silica as main components, and a catalyst layer (upper layer) including a composite oxide (C) consisting of tungsten oxide, ceria, and zirconia, at the surface of an integral structure-type substrate, wherein a composition of the composite oxide (C) is tungsten oxide: 1 to 50% by weight, ceria: 1 to 60% by weight, and zirconia: 30 to 90% by weight.
US08865613B2 Catalyst for synthesis of hydrocarbons from CO and H2 and preparation method thereof
The disclosed technology relates to nanotechnology, petrochemistry, gas chemistry, coal chemistry, in particular to a catalyst based on carbon nanotubes for synthesis of hydrocarbons from CO and H2 and a preparation method thereof. The carbon nanotubes fixed in the catalyst pellet pores improve mass and heat transfer in the catalyst pellet and the catalyst bed.
US08865612B2 Titanium-based material having visible light response and excellent in photocatalytic activity and method of production of same
The provision of beautiful colored titanium which is excellent in adhesion of the pure titanium or a titanium alloy with the base material, is excellent in photocatalytic activity, and further is excellent in design properties and a method of production of the same which is excellent in productivity and uses an anodic oxidation process is made the object. A titanium-based material having visible light response and excellent in photocatalytic activity characterized in that the material has pure titanium or titanium alloy as a base material, a thickness of a titanium oxide layer which is present on its surface is 0.1 μm to 5.0 μm in range, said titanium oxide layer contains anatase-type titanium dioxide and titanium bonded with hydroxy groups, and further said titanium oxide layer contains nitrogen and carbon respectively in 0.5 to 30 mass %.
US08865607B2 Infiltrated silicon carbide bodies and methods of making
A composite article including a body made of recrystallized silicon carbide and an infiltrant, wherein the body comprises a static impact resistance of at least about 1800 MPa.
US08865605B2 Antimicrobial composition for finishing textiles
An antimicrobial composition comprising an organic antimicrobial component (K) and at least one metal salt component (M) and also, where appropriate, a solvent (L) and further auxiliary components, which comprises as organic component (K) at least one compound of the general formula (I) where the radicals independently have for example the following meanings: R1 is a branched or unbranched alkyl radical having 1 to 12 carbon atoms, R2 is a branched or unbranched alkyl radical having 1 to 12 carbon atoms, R3 is a branched or unbranched alkyl radical having 1 to 12 carbon atoms, R4 is a branched or unbranched alkyl radical having 1 to 18 carbon atoms, R5 is a branched or unbranched alkyl radical having 1 to 18 carbon atoms, R6 is a branched or unbranched alkyl radical having 8 to 18 carbon atoms; n is an integer from 1 to 6, and which comprises as metal salt component (M) at least one salt of a di- to pentavalent metal, is useful for durable finishing of textiles.
US08865604B2 Bulk carbon nanotube and metallic composites and method of fabricating
In one embodiment, a bulk carbon nanotube and metallic composite is provided. The bulk carbon nanotube and metallic composite includes a bulk carbon nanotube material layer including a plurality of carbon nanotubes, and a metal film applied across the bulk carbon nanotube material layer. The metal film penetrates into the interstices between individual carbon nanotubes to reduce an electrical resistance between the plurality of carbon nanotubes.
US08865603B2 Laser annealing systems and methods with ultra-short dwell times
Laser annealing systems and methods for annealing a semiconductor wafer with ultra-short dwell times are disclosed. The laser annealing systems can include one or two laser beams that at least partially overlap. One of the laser beams is a pre-heat laser beam and the other laser beam is the annealing laser beam. The annealing laser beam scans sufficiently fast so that the dwell time is in the range from about 1 μs to about 100 μs. These ultra-short dwell times are useful for annealing product wafers formed from thin device wafers because they prevent the device side of the device wafer from being damaged by heating during the annealing process. Embodiments of single-laser-beam annealing systems and methods are also disclosed.
US08865602B2 Edge ring lip
Embodiments of the invention generally relate to a support ring to support a substrate in a process chamber. In one embodiment, the support ring comprises an inner ring, an outer ring connecting to an outer perimeter of the inner ring through a flat portion, an edge lip extending radially inwardly from an inner perimeter of the inner ring to form a supporting ledge to support the substrate, and a substrate support formed on a top surface of the edge lip. The substrate support may include multiple projections extending upwardly and perpendicularly from a top surface of the edge lip, or multiple U-shaped clips securable to an edge portion of the edge lip. The substrate support thermally disconnects the substrate from the edge lip to prevent heat loss through the edge lip, resulting in an improved temperature profile across the substrate with a minimum edge temperature gradient.
US08865601B2 Methods for preparing a semiconductor wafer with high thermal conductivity
This invention generally relates to an epitaxial silicon semiconductor wafer with increased thermal conductivity to transfer heat away from a device layer, while also having resistance to common failure mechanisms, such as latch-up failures and radiation event failures. The semiconductor wafer comprises a lightly-doped device layer, a highly-doped protective layer, and a lightly-doped substrate. The invention is also directed to a process for forming such an epitaxial silicon wafer.
US08865599B2 Self-leveling planarization materials for microelectronic topography
Planarization methods and microelectronic structures formed therefrom are disclosed. The methods and structures use planarization materials comprising fluorinated compounds or acetoacetylated compounds. The materials are self-leveling and achieve planarization over topography without the use of etching, contact planarization, chemical mechanical polishing, or other conventional planarization techniques.
US08865584B2 Semiconductor device and manufacturing method thereof
A semiconductor device of the present invention has a purpose to form a structure of preventing outflow of solder at low costs. A semiconductor element is bonded to a substrate through a solder layer. An outflow-preventing part is provided to surround the solder layer to prevent solder outflow during soldering. The outflow-preventing part is formed by a cold spray method and has a surface in an oxidized state.
US08865581B2 Hybrid gate last integration scheme for multi-layer high-k gate stacks
A method for manufacturing a dual workfunction semiconductor device using a hybrid gate last integration scheme is described. According to one embodiment, the method includes heat-treating a first high-k film at a first heat-treating temperature to diffuse a first chemical element from a first cap layer into the first high-k film in a device region to form a first modified high-k film. The method further includes a gate-last processing scheme to form recessed features defined by sidewall spacers in the device regions and depositing a second high-k film in the recessed features. Some embodiments include forming an oxygen scavenging layer on the first high-k film, where the heat-treating the first high-k film scavenges oxygen from an interface layer to eliminate or reduce the thickness of an interface layer.
US08865578B2 Method of manufacturing polycrystalline silicon layer, and method of manufacturing transistor having the polycrystalline silicon layer
An embodiment is directed to a method of manufacturing a polycrystalline silicon layer, the method including providing a crystallization substrate, the crystallization substrate having an amorphous silicon layer on a first substrate, providing a reflection substrate, the reflection substrate having a first region with a reflection panel therein and a second region without the reflection panel, disposing the crystallization substrate and the reflection substrate on one another, and selectively crystallizing the amorphous silicon layer by directing a laser beam onto the crystallization substrate and the reflection substrate, and reflecting the laser beam from the reflection panel.
US08865575B2 Fabrication of III-nitride semiconductor device and related structures
A method of fabricating a III-nitride power semiconductor device that includes growing a transition layer over a substrate using at least two distinct and different growth methods.
US08865571B2 Dislocation engineering using a scanned laser
A method for manipulating dislocations from a semiconductor device includes directing a light-emitting beam locally onto a surface portion of a semiconductor body that includes active regions of the semiconductor device and manipulating a plurality of dislocations located proximate to the surface portion of the semiconductor body utilizing the light-emitting beam. Manipulating the plurality of dislocations includes directly scanning the plurality of dislocations with the light-emitting beam to manipulate a location of each of the plurality of dislocations on the surface portion of the semiconductor body by adjusting a temperature of the surface portion of the semiconductor body corresponding to the plurality of dislocations and adjusting a scan speed of the a light-emitting beam.
US08865569B2 Method and apparatus for dividing thin film device into separate cells
A method and apparatus for dividing a thin film device having a first layer which is a lower electrode layer, a second layer which is an active layer and a third layer which is an upper electrode layer, the layers each being continuous over the device, into separate cells which are electrically interconnected in series. The dividing of the cells and the electrical connection between adjacent cells are carried out in a single pass of a process head across the device, the process head performing the following steps in the single pass: a) making a first cut through the first, second and third layers; b) making a second cut through the second and third layers, the second cut being adjacent to the first cut; c) making a third cut through the third layer the third cut being adjacent to the second cut and on the opposite side of the second cut to the first cut; d) using a first ink jet print head to deposit a non-conducting material into the first cut; and e) using a second ink jet print head to apply conducting material to bridge the non-conducting material in the first cut and either fully or partially fill the second cut such to form an electrical connection between the first layer and the third layer, wherein step (a) precedes step (d), step (d) precedes step (e) and step (b) precedes step (e), (otherwise the steps may be carried out in any order in the single pass of the process head across the device). The process head may comprise a first part above the device and a second part beneath the device, at least one of the cuts being formed by a laser beam from the second part of the process head. The thin film device may be a solar panel, a lighting panel or a battery.
US08865566B2 Method of cutting semiconductor substrate
Multiphoton absorption is generated, so as to form a part which is intended to be cut 9 due to a molten processed region 13 within a silicon wafer 11, and then an adhesive sheet 20 bonded to the silicon wafer 11 is expanded. This cuts the silicon wafer 11 along the part which is intended to be cut 9 with a high precision into semiconductor chips 25. Here, opposing cut sections 25a, 25a of neighboring semiconductor chips 25, 25 are separated from each other from their close contact state, whereby a die-bonding resin layer 23 is also cut along the part which is intended to be cut 9. Therefore, the silicon wafer 11 and die-bonding resin layer 23 can be cut much more efficiently than in the case where the silicon wafer 11 and die-bonding resin layer 23 are cut with a blade without cutting a base 21.
US08865563B2 Film embedding method and semiconductor device
A method of forming an embedded film comprises depositing a first layer on a second layer that is disposed on a substrate and includes a material different from materials included in the first layer, forming an aperture through the first layer and into the second layer, the aperture having a side surface that includes an exposed portion of the first layer and an exposed portion of the second layer, bringing a material that includes organic molecules into contact with the exposed portion of the first layer and the exposed portion of the second layer to form a monomolecular film that covers the side surface, and forming the embedded film in the aperture with a material having a high enough affinity to the monomolecular film to substantially fill the aperture.
US08865561B2 Back-gated substrate and semiconductor device, and related method of fabrication
A method of forming a semiconductor device is disclosed. The method includes forming a set of doped regions in a substrate; forming a crystalline dielectric layer on the substrate, the crystalline dielectric layer including an epitaxial oxide; forming a semiconductor layer on the crystalline dielectric layer, the semiconductor layer and the crystalline dielectric layer forming an extremely thin semiconductor-on-insulator (ETSOI) structure; and forming a set of devices on the semiconductor layer, wherein at least one device in the set of devices is formed over a doped region.
US08865558B2 Method of forming a phase change material layer pattern and method of manufacturing a phase change memory device
A method of forming a phase change material layer pattern includes forming a phase change material layer partially filling an opening through an insulating interlayer. A plasma treatment process is performed on the phase change material layer to remove an oxide layer on a surface of the phase change material layer. A heat treatment process is performed on the phase change material layer to remove a void or a seam in the phase change material layer, sufficiently filling the opening.
US08865553B2 Semiconductor component with a window opening as an interface for ambient coupling
A window opening in a semiconductor component is produced on the basis of a gate structure which serves as an efficient etch resist layer in order to reliably etch an insulation layer stack without exposing the photosensitive semiconductor area. The polysilicon in the gate structure is then removed on the basis of an established gate etching process, with the gate insulation layer preserving the integrity of the photosensitive semiconductor material.
US08865549B2 Recessed channel insulated-gate field effect transistor with self-aligned gate and increased channel length
A metal-oxide-semiconductor transistor (MOS) and method of fabricating the same, in which the effective channel length is increased relative to the width of the gate electrode. A dummy gate electrode overlying dummy gate dielectric material is formed at the surface of the structure, with self-aligned source/drain regions, and dielectric spacers on the sidewalls of the dummy gate structure. The dummy gate dielectric underlies the sidewall spacers. Following removal of the dummy gate electrode and the underlying dummy gate dielectric material, including from under the spacers, a silicon etch is performed to form a recess in the underlying substrate. This etch is self-limiting on the undercut sides, due to the crystal orientation, relative to the etch of the bottom of the recess. The gate dielectric and gate electrode material are then deposited into the remaining void, for example to form a high-k metal gate MOS transistor.
US08865546B2 Method for manufacturing a non-volatile semiconductor memory device having contact plug formed on silicided source/drain region
A method for manufacturing a semiconductor device includes the steps of forming a flash memory cell provided with a floating gate, an intermediate insulating film, and a control gate, forming first and second impurity diffusion regions, thermally oxidizing surfaces of a silicon substrate and the floating gate, etching a tunnel insulating film in a partial region through a window of a resist pattern; forming a metal silicide layer on the first impurity diffusion region in the partial region, forming an interlayer insulating film covering the flash memory cell, and forming, in a first hole of the interlayer insulating film, a conductive plug connected to the metal silicide layer.
US08865543B2 Ge-based NMOS device and method for fabricating the same
The embodiments of the present invention provide a Ge-based NMOS device structure and a method for fabricating the same. By using the method, double dielectric layers of germanium oxide (GeO2) and metal oxide are deposited between the source/drain region and the substrate. The present invention not only reduces the electron Schottky barrier height of metal/Ge contact, but also improves the current switching ratio of the Ge-based Schottky and therefore, it will improve the performance of the Ge-based Schottky NMOS transistor. In addition, the fabrication process is very easy and completely compatible with the silicon CMOS process. As compared with conventional fabrication method, the Ge-based NMOS device structure and the fabrication method in the present invention can easily and effectively improve the performance of the Ge-based Schottky NMOS transistor.
US08865541B2 Diode isolated drain extended NMOS ESD cell
An integrated circuit contains a voltage protection structure having a diode isolated DENMOS transistor with a guard element proximate to the diode and the DENMOS transistor. The guard element includes an active area coupled to ground. The diode anode is connected to an I/O pad. The diode cathode is connected to the DENMOS drain. The DENMOS source is grounded. A process of forming the integrated circuit is also disclosed.
US08865536B2 Semiconductor device and manufacturing method thereof
As for a bypass capacitor, a first capacitor insulating film, together with a tunnel insulating film of a storage element, is formed of a first insulating film, a first electrode being a lower electrode, together with floating gate electrodes of the storage element, is formed of a doped·amorphous silicon film (a crystallized one), a second capacitor insulating film, together with a gate insulating film of transistors of 5 V in a peripheral circuit, is formed of a second insulating film, and a second electrode being an upper electrode, together with control gate electrodes of the storage element and gate electrodes of the transistors in the peripheral circuit, is formed of a polycrystalline silicon film.
US08865535B2 Fabricating 3D non-volatile storage with transistor decoding structure
Disclosed herein are techniques for fabricating a 3D stacked memory device having word line (WL) select gates. The bodies of the WL select gates may be formed from the same material (e.g., highly doped polysilicon) that the word lines are formed. Desired doping profiles in a body of a WL select gate may be achieved by various techniques such as counter-doping. The WL select gates may include TFTs that formed by etching holes in the layer in which word lines are formed. Gate electrodes and gate dielectrics may be formed in the holes. Bodies may be formed in the polysilicon outside of the holes.
US08865533B2 Thin film transistor array panel and method of manufacturing the same
A TFT array panel and a manufacturing method thereof.The TFT array panel includes an insulation substrate, a plurality of gate lines, a plurality of first dummy wiring lines, a gate insulating layer, and a plurality of data lines. The insulation substrate has a display area for displaying an image and a peripheral area outside the display area. The plurality of gate lines are formed in the display area and in a portion of the peripheral area. The plurality of first dummy wiring lines are insulated from the gate lines and formed in the peripheral area. The gate insulating later is formed on the gate lines and the first dummy wiring lines, and has at least one contact hole exposing at least lateral end portions of the first dummy wiring lines. The plurality of gate lines are formed on the gate insulating layer, define a plurality of pixel areas that form the display area by being insulated from the plurality of gate lines and crossing the plurality of gate lines, and are connected with the at least lateral end portions of the first dummy wiring lines through the at least one contact hole. With this configuration, data voltages can be efficiently applied to respective pixel electrodes of the display area even though the data line, particularly the data fan-out unit, in the peripheral area is disconnected.
US08865531B1 Multi-direction wiring for replacement gate lines
A post-planarization recess etch process is employed in combination with a replacement gate scheme to enable formation of multi-directional wiring in gate electrode lines. After formation of disposable gate structures and a planarized dielectric layer, a trench extending between two disposable gate structures are formed by a combination of lithographic methods and an anisotropic etch. End portions of the trench overlap with the two disposable gate structures. After removal of the disposable gate structures, replacement gate structures are formed in gate cavities and the trench simultaneously. A contiguous gate level structure can be formed which include portions that extend along different horizontal directions.
US08865526B2 Semiconductor device and method for manufacturing a semiconductor device
A semiconductor device mountable to a substrate is provided. The device includes a semiconductor package having at least one semiconductor die, an electrically conductive attachment region, and a packaging material in which is embedded the semiconductor die and a first portion of the electrically conductive attachment region contacting the die. A metallic shell encloses the embedded semiconductor die and the first portion of the electrically conductive attachment region.
US08865525B2 Method of making cavity substrate with built-in stiffener and cavity substrate manufactured thereby
A method of making a cavity substrate. The method includes: preparing a supporting board including a stiffener, a bump/flange sacrificial carrier, an adhesive and an electrical pad, wherein the adhesive bonds the stiffener to the sacrificial carrier; forming a careless build-up circuitry on the supporting board in contact with the bump and the stiffener; and removing the bump to form a cavity and expose the electrical pad from a closed end of the cavity; wherein the cavity is laterally covered and surrounded by the adhesive. A semiconductor device can be mounted on the cavity substrate and electrically connected to the electrical pad. The careless buildup circuitry provide signal routing for the semiconductor device while the built-in stiffener can provide adequate mechanical support for the careless build-up circuitry and the semiconductor device.
US08865524B2 Lead carrier with print-formed package components
A lead carrier provides support for an integrated circuit chip and associated leads during manufacture as packages containing such chips. The lead carrier includes a temporary support member with multiple package sites. Each package site includes a die attach pad surrounded by a plurality of terminal pads. The pads are formed of a sintered electrically conductive material. A chip is mounted upon the die attach pad and wire bonds extend from the chip to the terminal pads. The pads, chip and wire bonds are all encapsulated within a mold compound. The temporary support member can be peeled away and then the individual package sites can be isolated from each other to provide completed packages including multiple surface mount joints for mounting within an electronics system board. Edges of the pads are contoured to cause the pads to engage with the mold compound to securely hold the pads within the package.
US08865518B2 Methods for forming resistive switching memory elements
Resistive switching memory elements are provided that may contain electroless metal electrodes and metal oxides formed from electroless metal. The resistive switching memory elements may exhibit bistability and may be used in high-density multi-layer memory integrated circuits. Electroless conductive materials such as nickel-based materials may be selectively deposited on a conductor on a silicon wafer or other suitable substrate. The electroless conductive materials can be oxidized to form a metal oxide for a resistive switching memory element. Multiple layers of conductive materials can be deposited each of which has a different oxidation rate. The differential oxidization rates of the conductive layers can be exploited to ensure that metal oxide layers of desired thicknesses are formed during fabrication.
US08865517B2 Method for manufacturing thin-film transistor active device and thin-film transistor active device manufactured with same
The present invention provides a method for manufacturing thin-film transistor active device and a thin-film transistor active device manufactured with the method. The method includes providing a substrate; forming a gate terminal on the substrate through sputtering and masking operations; forming a gate insulation layer on the gate terminal through CVD; forming an oxide semiconductor layer on the gate insulation layer through sputtering and masking operations; forming a first protection layer on the oxide semiconductor layer through CVD, forming a metal layer on the first protection layer through sputtering, and forming a data line electrode through masking operation; forming a second protection layer on the first protection layer and the data line electrode through CVD and forming first, second, and third bridging holes through masking operation; forming a transparent conductive layer on the second protection layer through sputtering and patternizing the transparent conductive layer through masking operation.
US08865512B2 Thin-film solar cell
Thin-film solar cells of the CIGS-type use two integrally formed buffer layers, a first ALD Zn(O,S) buffer layer on top of the CIGS-layer and a second ALD ZnO-buffer layer on top of the first buffer layer. Both buffer layers are deposited in the same process step using ALD (atom layer deposition). The technology also relates to a method of producing the cell and a process line for manufacturing of the cell structure.
US08865510B2 Method of manufacturing solar cell
A solar cell is manufactured, which includes: a solar cell substrate including a semiconductor substrate, a p-type surface and an n-type surface exposed on a first principal surface, and a texture structure in a second principal surface; a p-side electrode disposed on the p-type surface; an n-side electrode disposed on the n-type surface; and an insulation layer formed on the first principal surface and isolating the p-side electrode and the n-side electrode from each other. The manufacturing method of the solar cell includes: forming an insulation film covering the first principal surface; forming the texture structure in the second principal surface; and removing part of the insulation film, thereby forming the insulation layer.
US08865509B2 Cleaning method of silicon substrate and manufacturing method of solar battery
A cleaning method of a silicon substrate includes a first step of etching a surface of a silicon substrate by a metal-ion-containing mixed aqueous solution of an oxidizing agent and hydrofluoric acid and of forming a porous layer on the surface of the silicon substrate, a second step of etching a pore of the porous layer by mixed acid mainly containing hydrofluoric acid and nitric acid and of forming texture on the surface of the silicon substrate, a third step of etching the surface of the silicon substrate on which the texture is formed with an alkaline chemical solution, and a fourth step of treating the silicon substrate etched by the alkaline chemical solution by ozone-containing water, of generating an air bubble within the pore formed in the silicon substrate, and of removing metal and organic impurities from within the pore.
US08865506B1 Roll-to-roll solution process method for fabricating CIGS solar cells and system for the same
A method for fabricating a solar cell commences by bonding a first metal-coated substrate to a second metal-coated substrate to provide a bonded substrate. The bonded substrate is then coated with a first precursor solution to provide a coated bonded substrate. Finally, the procedure de-bonds the coated bonded substrate to provide a first solar cell device and a second solar cell device. A system for fabricating the solar cell comprises a first precursor solution deposition system containing a first precursor solution for deposition on a substrate, a first heating element for heating the substrate after deposition of the first precursor solution, a second precursor solution deposition system containing a second precursor solution for deposition on the substrate, and a second heating element for heating the substrate after deposition of the second precursor solution.
US08865504B2 Patterning
A method for patterning an article, the article comprising a first layer of a first material, a first major surface of the first layer being in intimate contact with some or all of a first major surface of a second layer of a second different material the method comprising providing a first thread carrying a first species to remove at least a portion of the first layer, and providing a second thread aligned with and adjacent the first thread and contacting the first and second threads with the first layer to remove at least part of the first layer.
US08865492B2 Method of forming current-injecting/tunneling light-emitting device
An apparatus and method for making same. Some embodiments include a light-emitting device having a light-emitting active region; a tunneling-barrier (TB) structure facing adjacent the active region; a TB grown-epitaxial-metal-mirror (TB-GEMM) structure facing adjacent the TB structure, wherein the TB-GEMM structure includes at least one metal is substantially lattice matched to the active region; and a conductivity-type III-nitride crystal structure adjacent facing the active region opposite the TB structure. In some embodiments, the active region includes an MQW structure. In some embodiments, the TB-GEMM includes an alloy composition such that metal current injectors have a Fermi energy potential substantially equal to the sub-band minimum energy potential of the MQW. Some embodiments further include a second mirror (optionally a GEMM) to form an optical cavity between the second mirror and the TB-GEMM structure. In some embodiments, at least one of the GEMM is deposited on, and lattice matched to, a substrate.
US08865489B2 Printed assemblies of ultrathin, microscale inorganic light emitting diodes for deformable and semitransparent displays
Described herein are printable structures and methods for making, assembling and arranging electronic devices. A number of the methods described herein are useful for assembling electronic devices where one or more device components are embedded in a polymer which is patterned during the embedding process with trenches for electrical interconnects between device components. Some methods described herein are useful for assembling electronic devices by printing methods, such as by dry transfer contact printing methods. Also described herein are GaN light emitting diodes and methods for making and arranging GaN light emitting diodes, for example for display or lighting systems.
US08865482B2 Method of detecting the circular uniformity of the semiconductor circular contact holes
A method of detecting the circular uniformity of semiconductor circular contact holes. Several detection circuit structures are disposed on the semiconductor wafer: N-type active regions and P-type active regions; silicon dioxide layers separate the N-type active regions from the P-type active regions; the N-type active regions are formed in the P well and the P-type active regions are formed in the N well; polysilicon gates bridge the N-type active regions and the P-type active regions; gate oxide layers insulate the P-type regions and the N-type regions from the polysilicon gates, so that the P-type regions and the N-type regions are independent; the N-type active regions connect with circular contact holes while the P-type active regions and the polysilicon gates connect with oval contact holes; a electron beam scanner detects the circular uniformity of the contact holes. This invention advantageously reflects effectively and comprehensively the circular uniformity of the contact holes.
US08865474B2 Automated laboratory system
An automated laboratory system and method allow high-throughput and fully automated processing of materials, such as liquids including genetic materials. The invention includes a variety of aspects that may be combined into a single system. For example, processing may be performed by a plurality of robotic-equipped modular stations, where each modular station has its own unique environment in which processes are performed. Transport devices, such as conveyor belts, may move objects between modular stations, saving movement for robots in the modular stations. Gels used for gel electrophoresis may be extruded, thus decreasing the time needed to form such gels. Robotically-operated well forming tools allow wells to be formed in gels in a registered and accurate way.
US08865473B2 Luminescence detecting apparatuses and methods
A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. A detecting apparatus may be configured so that light from luminescent samples pass through a collimator, a first lens, a filter, and a camera lens, whereupon an image is created by the optics on the charge-coupled device (CCD) camera. The detecting apparatus may further include central processing control of all operations, multiple wavelength filter wheel, and/or a robot for handling of samples and reagents.
US08865470B2 Instrument setup system for a fluorescence analyzer
The present invention reagents and methods for setting up an instruments having a multiplicity of detector channels for analyzing a multiplicity of fluorescent dyes. The present invention is particularly applicable in the field of flow cytometry.
US08865469B2 Methods of transforming a Listeria
Site-specific Listeria integration vectors and methods for their use are provided. The subject vectors include a bacteriophage integrase gene and a bacteriophage attachment site, where in many embodiments the bacteriophage that is the source of these elements is a listeriophage. In certain embodiments, the subject vectors further include a multiple cloning site, where the multiple cloning site may further include a polypeptide coding sequence, e.g., for a heterologous antigen. The subject vectors and methods find use in a variety of different applications, including the study of Listeria species and the preparation of Listeria vaccines.
US08865468B2 Homologous recombination in an algal nuclear genome
Exemplary transformation methods are provided for introducing deoxyribonucleic acid (DNA) into the nucleus of an algal cell. A transformation construct may be prepared, with the transformation construct having a first sequence of DNA similar to a corresponding first sequence of nuclear DNA, a second sequence of DNA similar to a corresponding second sequence of the nuclear DNA, and a sequence of DNA of interest inserted between the first and second sequences of DNA of the transformation construct. A target sequence of DNA inserted between the first and second corresponding sequences of the nuclear DNA may be transformed, resulting in replacement of the target sequence of DNA with the sequence of DNA of interest. Also provided are exemplary transformation constructs, with some transformation constructs having a first sequence of DNA similar to a corresponding first sequence of nuclear DNA of an algal cell, a second sequence of DNA similar to a corresponding second sequence of nuclear DNA of the algal cell, and a sequence of DNA of interest inserted between the first and second sequences of the transformation construct.
US08865467B2 Single lentiviral vector system for induced pluripotent (iPS) stem cells derivation
The present invention is based on the discovery that a single lentiviral vector expressing multiple individual transcription factor proteins from a single multi-cistronic mRNA can reprogram a fibroblast cell to a stem cell-like cell. These reprogrammed induced pluripotent stem (iPS) cells are pluripotent. Additions of the Cre-LoxP sequences into the single lentiviral vector facilitate excision of the vector after reprogramming in achieved. Addition of a maker gene into the single lentiviral vector facilitates detection of the presence of the vector in an iPS. The invention provides compositions and methods of producing iPS cells using a single multi-cistronic lentiviral vector.
US08865465B2 Polymer matrices for cell culture
Synthetic cell culture surfaces, including a hydrophobe modified cellulose or an hydroxylated acrylate polymer composition and optionally including a silica source, cell culture coating and cell culture articles incorporating the composition, and methods of making and using the articles for cell culture, as defined herein.
US08865464B2 Microfluidic cell culture device
Microfluidic devices for cell culturing and methods for using the same are disclosed. One device includes a substrate and membrane. The substrate includes a reservoir in fluid communication with a passage. A bio-compatible fluid may be added to the reservoir and passage. The reservoir is configured to receive and retain at least a portion of a cell mass. The membrane acts as a barrier to evaporation of the bio-compatible fluid from the passage. A cover fluid may be added to cover the bio-compatible fluid to prevent evaporation of the bio-compatible fluid.
US08865456B2 Nucleic acid collection device and nucleic acid collection amount estimation method
The present invention provides a nucleic acid collection device that can estimate the nucleic acid collection amount when collecting nucleic acids from a biological sample containing nucleic acids. The nucleic acid collection device comprises a sucking and discharging unit for sucking in and forcing out a sample containing nucleic acids, a collector for collecting the nucleic acids by sucking in and forcing out the sample using the sucking and discharging unit, a pressure measurer for measuring a discharging pressure when forcing out the sample and a sucking pressure when sucking in the sample, and measuring a differential pressure that is the difference between the discharging pressure and the sucking pressure, and an estimator for estimating the collection amount of nucleic acids collected based on the differential pressure.
US08865454B2 Flow through system, flow through device and a method of performing a test
The invention relates to a flow through system for quantifying a target component in a liquid. The flow through system comprises a flow-through device comprising a flow path comprising a marker section, a capture section downstream to said marker section, and at least two quantification sections. The marker section comprises a non-immobilized marker. The capture section comprises a capture zone with an immobilized capture agent, and the at least two quantification sections comprise a pre-capture quantification section placed downstream to the marker section and up stream to the capture section, and a post-capture quantification section placed downstream to the capture section. The system further comprises a quantification unit for each of said quantification sections. The quantification unit(s) being arranged to quantify marker containing components and/or particles passing through said respective quantification sections. The invention also relates to a flow through device for such flow through system and a method of determining the amount of target component in a liquid using a flow through system.
US08865451B2 Transgenic algae engineered for higher performance
The present disclosure relates to transgenic algae having increased growth characteristics, and methods of increasing growth characteristics of algae. In particular, the disclosure relates to transgenic algae comprising a glutamine phenylpyruvate transaminase transgene and to transgenic algae comprising a glutamine phenylpyruvate transaminase transgene and a glutamine synthetase.
US08865445B2 Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
US08865440B2 Microorganisms having enhanced resistance to acetate and methods of use
The present invention provides isolated or genetically modified strains of microorganisms that display enhanced resistance to acetate as a result of increased expression of a sodium proton antiporter. The present invention also provides methods for producing such microbial strains, as well as related promoter sequences and expression vectors. Further, the present invention provides methods of producing alcohol from biomass materials by using microorganisms with enhanced resistance to acetate.
US08865438B2 Process for the preparation of a monovalent succinate salt
A process for the preparation of a monovalent succinate salt includes: a) fermenting a carbohydrate source to succinic acid by means of a micro-organism, b) adding a alkaline earth metal hydroxide, carbonate and/or hydrogencarbonate, the alkaline earth metal being calcium or magnesium, as neutralising agent during the fermentation in an aqueous medium and causing the formation of calcium succinate or magnesium succinate, c) reacting the alkaline earth metal succinate salt in an aqueous medium with a monovalent hydroxide, carbonate and/or hydrogencarbonate base to form an alkaline earth metal hydroxide, carbonate and/or hydrogencarbonate and a monovalent succinate salt, d) separating the monovalent succinate salt from the alkaline earth metal hydroxide, carbonate and/or hydrogencarbonate, and e) recycling the alkaline earth metal hydroxide, carbonate and/or hydrogencarbonate to step b.
US08865437B2 Enzymes useful for peracid production
Acetyl xylan esterases and variants thereof having perhydrolytic activity are provided for producing peroxycarboxylic acids from carboxylic acid esters and a source of peroxygen. Multi-component peracid generation systems comprising an enzyme catalyst having perhydrolytic activity are also provided, as are methods of using the present enzyme catalyst to produce peroxycarboxylic acids. The polypeptide having perhydrolytic activity may be used to produce peroxycarboxylic acids suitable for use in a variety of applications such as cleaning, disinfecting, sanitizing, bleaching, wood pulp processing, paper pulp processing, and personal care applications.
US08865435B2 Enzymes useful for peracid production
Acetyl xylan esterases and variants thereof having perhydrolytic activity are provided for producing peroxycarboxylic acids from carboxylic acid esters and a source of peroxygen. Multi-component peracid generation systems comprising an enzyme catalyst having perhydrolytic activity are also provided, as are methods of using the present enzyme catalyst to produce peroxycarboxylic acids. The polypeptide having perhydrolytic activity may be used to produce peroxycarboxylic acids suitable for use in a variety of applications such as cleaning, disinfecting, sanitizing, bleaching, wood pulp processing, paper pulp processing, and personal care applications.
US08865433B2 Method for qualitative and quantitative detection of common wheat
Disclosed are: a method for detecting common wheat among from wheat varieties contained in a sample of interest such as a food raw material or a processed food specifically, with high sensitivity, and in a qualitative and/or quantitative manner; a method for discriminating between common wheat and a wheat variety other than common wheat (e.g., durum wheat) contained in a food raw material or a processed food and detecting the common wheat in a qualitative and/or quantitative manner; and a primer set, a nucleic acid probe, and a detection kit, each of which can be used in the methods employing a PCR method. Specifically disclosed are: a method for detecting the occurrence of common wheat in a sample of interest, which comprises carrying out a PCR method using a nucleic acid extracted from the sample as a template and using a primer comprising the nucleotide sequence represented by SEQ ID NO:5 and a primer comprising the nucleotide sequence represented by SEQ ID NO:6 and detecting the occurrence of a PCR amplification product; and a method for detecting the occurrence of common wheat in a sample of interest, which comprises carrying out a quantitative PCR method using a nucleic acid extracted from the sample as a template and using a primer comprising the nucleotide sequence represented by SEQ ID NO:5, a primer comprising the nucleotide sequence represented by SEQ ID NO:6 and a nucleic acid probe comprising the nucleotide sequence represented by SEQ ID NO:11 and detecting the occurrence of common wheat qualitatively and/or quantitatively.
US08865427B2 Perifusion device
A perifusion device includes at least one sample container for cells, the sample container having an inlet and an outlet. The container receives test liquid through the inlet and discharges the liquid through the outlet. A manifold having a plurality of liquid inlets, control valves, and liquid outlets can be provided. A receptacle housing has a plurality of receptacles. A drive is connected to the receptacle housing for moving the receptacle housing. A programmable controller can be provided to control movement of the receptacle housing. The test liquid includes at least one stimuli for the cells. The liquid collected in the receptacles is analyzed to determine the response of the cells to the stimuli.
US08865426B2 Screening method using gelatinase-mediated EphA4 cleavage reaction as an indicator
The object of the present invention is to provide a method for screening a substance that affects gelatinase-mediated EphA4 processing. The present invention provides a method for screening a substance that affects gelatinase-mediated EphA4 processing, which comprises the steps of: (a) allowing a first biological composition containing gelatinase or a biologically active fragment thereof to be contacted with a second biological composition containing EphA4 in the presence and absence of a candidate substance; (b) measuring the presence or amount of the EphA4 ectodomain and/or endodomain fragment; and (c) selecting the candidate substance as a substance that affects gelatinase-mediated EphA4 processing if the results of the step (b) measured in the presence of the candidate substance are changed in comparison with the results of the step (b) measured in the absence of the candidate substance.
US08865425B2 Reagent and reagent kit for measurement of FDP, and measurement method
The present invention relates to a reagent for the measurement of FDP comprising a carrier sensitized with at least two monoclonal antibodies selected from three monoclonal antibodies having different reactivity towards FDP. The present invention also relates to a reagent kit comprising the reagent and a method for measurement of FDP using the reagent or reagent kit.
US08865423B2 Method and kit for quantitatively determining small, dense LDL cholesterol
A method for fractional measurement of small, dense LDL, which is adaptable for an autoanalyzer, and a reagent for measurement, are provided, making it possible to conduct rapid and convenient analysis with good sensitivity without pretreatment of a specimen. The method for quantitatively determining small, dense LDL cholesterol in a sample comprises the steps of: (1) eliminating cholesterol in LDL other than small, dense LDL in the presence of phospholipase; and (2) quantitatively determining cholesterol in lipoproteins remaining in step (1) above.
US08865419B2 Method for the screening of conserved secreted proteins
Conserved polypeptides from protozoan parasitic species which are secreted through the endoplasmic reticulum/Golgi dependent secretory pathway, their identification and their use.
US08865413B2 Pancreatic cancer targets and uses thereof
The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or nucleic acid molecules differentially expressed in pancreatic diseases (PCAT) and antibodies binds to PCAT. The present invention provides that PCAT is used as targets for screening agents that modulates the PCAT activities. Further, the present invention provides methods for treating diseases associated with pancreas.
US08865412B2 Methods and assays for oversulfated glycosaminoglycans
Methods and assays for oversulfated glycosaminoglycans are provided. In an embodiment, the present disclosure provides a method for detecting oversulfated glycosaminoglycan (OS-GAG) in a heparin sample. The method comprises placing the heparin sample onto a support comprising immobilized heparin and contacting the heparin sample on the support with a binding compound that attaches to the heparin and forms a heparin-binding compound complex. The binding compound also has a greater affinity for attaching to the OS-GAG than to the heparin in the heparin sample and forms an OS-GAG-binding compound complex. The method can further comprise detecting an amount of the heparin-binding compound complex on the support, and determining an amount of OS-GAG in the heparin sample based on the amount of the heparin-binding compound complex on the support.
US08865401B2 Purification and concentration of proteins and DNA from a complex sample using isotachophoresis and a device to perform the purification
A method of simultaneously co-purifying and concentrating nucleic acid and protein targets is described. The method includes automation of the entire sample preparation process, performed by having an analyst add a sample into a device that performs all of the steps necessary to prepare a sample for analysis. The method provides for samples that are not split during the sample preparation process and where common purification methods can be used for purifying multiple analytes.
US08865397B2 Method for cooling an organ with a transparent cooling gel
For cooling organs and tissues in transplantation medicine, only ice preparations are used so far which are not soft like a gel and are brought to the necessary degree of comminution by mechanically comminuting frozen, sterile, pyrogen-free isotonic infusion solutions, such as 5% glucose or 0.9% saline, with great effort. The lack of gel-like consistency of the preparations and the expensive production process are very disadvantageous.Therefore, it was necessary to produce a cooling preparation for transplantation medicine, which in a temperature range from −5° C. to 4° C. is gel-like and soft, transparent and sufficiently mechanically stable and yet remains formable. In accordance with the invention, such preparation can be produced from gelatin solutions in the concentration range of 3-20 wt-%, which are isotonized or adjusted to 280-650 mosmol/kg and are almost pH-neutral, by simple cooling and/or freezing.
US08865395B2 Method of forming resist pattern
A method of forming a resist pattern, comprising: a step of forming a resist film on a substrate using a resist composition containing a base component (A) which exhibits decreased solubility in an organic solvent under action of acid and an acid-generator component (B) which generates acid upon exposure; a step of subjecting the resist film to exposure; a step of patterning the resist film by a negative-tone development using a developing solution containing the organic solvent to form a resist pattern; a step of applying a coating material to the resist pattern, thereby forming a coating film; a step of performing a thermal treatment at a temperature lower than the softening point of the resist pattern, thereby heat shrinking the coating film to narrow an interval between the resist pattern; and a step of removing the coating film.
US08865392B2 Photosensitive resin composition and cured product thereof
Disclosed is a photosensitive resin composition containing a cationic photopolymerization initiator (A) and an epoxy resin (B) having two or more epoxy groups in each molecule, which is characterized in that the cationic photopolymerization initiator (A) is a cationic photopolymerization initiator (A-1) that is represented by formula (1).
US08865391B2 Chemically amplified negative resist composition, photo-curable dry film, making method, pattern forming process, and electric/electronic part protecting film
A chemically amplified negative resist composition is provided comprising (A) a resin having a crosslinking group, (B) a crosslinker, (C) a photoacid generator capable of generating an acid upon exposure to light of wavelength 190-500 nm, (D) a solvent, and (E) an isocyanuric acid. The resist composition overcomes the stripping problem that the film is stripped from metal wirings of Cu or Al, electrodes, and SiN substrates.
US08865388B2 Electrophotographic toner and process for producing electrophotographic toner
Disclosed is an decolorizable electrophotographic toner, containing a binder resin, an electron-donating color-developable agent, and a wax having a color-developing action and having an acid value of 60 mgKOH/g or more.
US08865385B2 Toner
The present invention provides a toner that gives satisfactory fixing image quality in both high-speed fixing process and low-speed fixing process and shows excellent image quality for a long time by inhibiting inside contamination even in repeated use. In a toner including toner particles containing a binder resin, a hydrocarbon wax, and a coloring agent, the hydrocarbon wax is prescribed by a relationship in total amounts of components having carbon atoms in specific ranges in thermal desorption and GC/MS analysis when heated at 200° C. for 10 minutes.
US08865383B2 Toner, toner set, developer, developer set, image forming apparatus, image forming method, and process cartridge
A toner comprising an amorphous polyester, a crystalline polyester that is forming domains in the toner, and a colorant that is being dispersed at least in the domains of the crystalline polyester. The toner may be obtained by dispersing an oil phase including the amorphous polyester or a precursor capable of producing the amorphous polyester, the crystalline polyester, the colorant, and an organic solvent, in an aqueous medium to prepare an O/W dispersion, the oil phase; and removing the organic solvent from the O/W dispersion.
US08865371B2 Membrane electrode assembly for polymer electrolyte fuel cell and polymer electrolyte fuel cell
The present invention provides a membrane electrode assembly for a polymer electrolyte fuel cell, including: an electrolyte membrane; a catalyst layer; and a conductive porous gas diffusion layer, in which an interface between the catalyst layer and the electrolyte membrane is provided with a groove for allowing one of passage and retention of a fluid, and a polymer electrolyte fuel cell employing the membrane electrode assembly. As a result, there is provided at low costs the membrane electrode assembly for a polymer electrolyte fuel cell having improved drainage performance and the polymer electrolyte fuel cell employing the membrane electrode assembly and having stable power generation performance.
US08865370B2 Energy storage integrated framework for portable electronic devices
Embodiments of the invention relate to a fuel cell system for a portable electronic device including one or more fuel storage components, adapted to store and deliver a fuel, one or more electronic components and one or more fuel cells in contact with at least one of the one or more fuel storage components and one or more electronic components. The one or more fuel storage components are adapted to provide a secondary function, in addition to storing and delivering fuel.
US08865364B2 Solid oxide fuel cell
A solid oxide fuel cell includes two or more power generating elements each having a cathode, an anode, and an electrolyte layer placed between the cathode and the anode; an interconnector electrically connecting the power generating elements and containing a chromite-based material; and a sealing portion provided between the electrolyte layer and the interconnector and not containing either Ni or ZrO2.
US08865362B2 Gaskets and bipolar plates for PEM fuel cells
A bipolar plate (1) in combination with a sealant (50, 70) for a PEM fuel cell, wherein the bipolar plate (1) has an anode side with first flow channels (20) for transport of a proton-donating fuel or a cathode side with second flow channels (12) for transport of proton-accepting fluid, or both, wherein a sealant (50, 70) is provided parallel with the bipolar plate (1) for sealing the bipolar plate against an adjacent electrolytic membrane (40). The sealant (50, 70) has fluid channels (54a, 54b, 74a, 74b) across the sealant (50, 70) for transport of proton-donating fuel or proton-accepting fluid, respectively, across the sealant and along the bipolar plate.
US08865361B2 Instrumented fluid-surfaced electrode
An electrochemical device (such as a battery) includes at least one electrode having a fluid surface and one or more sensors configured to detect an operating condition of the device. Fluid-directing structures may modulate flow or retain fluid in response to the sensors. An electrolyte within the device may also include an ion-transport fluid, for example infiltrated into a porous solid support.
US08865360B2 Fuel cell system for a vehicle
A fuel cell system for a vehicle includes a burner for producing a heat flow by combustion of a fuel gas which reacts with an oxidant. A heating heat exchanger provided to heat a vehicle passenger compartment is arranged in a coolant circuit of the fuel cell system, and is externally heated, at least at times, by the burner.
US08865347B2 Digital alloys and methods for forming the same
Alloys of tunable compositions and corresponding optical, electrical and mechanical properties are described. Also described are their uses in optoelectronic devices and material interfaces.
US08865341B2 Electrochemical cell packaging material
Provided is a packaging material for electrochemical cells which has an identification mark that can be recognized from the outside and that is difficult to forge. The packaging material comprises a multilayer film which has a structure formed by laminating a base layer (11), an adhesive layer (13), a metal foil layer (12), an acid-modified polyolefin layer (14), and a heat-sealable layer (15) in this order, wherein the base layer (11) comprises both a oriented polyester film (11b) and a oriented nylon film (11e) with a printed layer (11c) provided on the surface of the oriented polyester film (11b) that faces the oriented nylon film (11e).
US08865337B2 Modular battery, an interconnector for such batteries and methods related to modular batteries
A modular battery includes a first planar battery cell having a first planar electrode surface, a second planar battery cell having a second planar electrode surface, and a compressible interconnector disposed between the first planar surface and the second planar surface and electrically connecting the first and second planar electrode surfaces. Other embodiments of a modular battery, an interconnector and methods are also disclosed.
US08865336B2 Separator for alkaline battery, method for producing the same, and battery
Provided is a separator for alkaline batteries which can not only prevent batteries from internal short circuit by inhibiting the dendrite formation at anode, but also enables to have a low electrical resistance. The separator for alkaline batteries comprises a composite sheet in which a base layer comprising a wet-type nonwoven material formed from alkaline resistant fibers is covered with a nanofiber layer comprising a modified polyvinyl alcohol fiber which has a fiber diameter of 10 to 1000 nm and a liquid absorption amount by fibers of 4.0 to 40.0 g/g after immersion in a 35% aqueous solution of KOH.
US08865333B2 Systems and methods for mitigating battery damage caused by coolant leaks
System and methods for mitigating battery damage in a vehicle including a liquid-cooled battery system. In certain embodiments, a system for mitigating damage caused by leaks of liquid coolant in a battery system may include a one or more coolant leak sensors. A coolant leak detection system communicatively coupled to the coolant leak sensors may be configured to detect an occurrence of a liquid coolant leak in the battery system based on information provided by the coolant leak sensors. One or more valves communicatively coupled with the coolant leak detection system may actuate by the coolant leak detection system when a leak of liquid coolant is detected, thereby allowing leaked liquid coolant to drain from the battery system.
US08865330B2 Lithium-ion battery
A battery comprise: a housing made by a metal or a metal alloy; a battery core in the housing comprising a positive plate, a separator and a negative plate; an electrolyte in the housing; a cover assembly having a positive terminal electrically connected with the positive plate and a negative terminal electrically connected with the negative plate; and a protection component to prevent the housing from being corroded by the electrolyte.
US08865328B2 Battery protecting circuit, method of controlling the same, and battery pack
A battery pack is disclosed. The battery pack has an analog front end which senses if a failure occurs in a microcontroller, and interrupts charging and discharging of the battery in response to the failure.
US08865326B2 Magnetoresistance device including layered ferromagnetic structure, and method of manufacturing the same
A layered ferromagnetic structure is composed of a first ferromagnetic layer positioned over a substrate; a second ferromagnetic layer positioned over the first ferromagnetic layer; and a first non-magnetic layer placed between the first and second ferromagnetic layers. The top surface of the first ferromagnetic layer is in contact with the first non-magnetic layer. The first ferromagnetic layer includes a first orientation control buffer that exhibits an effect of enhancing crystalline orientation of a film formed thereon.
US08865324B2 Production method for a bulk SiC single crystal with a large facet and monocrystalline SiC substrate with homogeneous resistance distribution
A method is used to produce a bulk SiC single crystal. A seed crystal is arranged in a crystal growth region of a growing crucible. An SiC growth gas phase is produced in the crystal growth region. The bulk SiC single crystal having a central longitudinal mid-axis grows by deposition from the SiC growth gas phase, the deposition taking place on a growth interface of the growing bulk SiC single crystal. The SiC growth gas phase is at least partially fed from an SiC source material and contains at least one dopant from the group of nitrogen, aluminum, vanadium and boron. At least in a central main growth region of the growth interface arranged about the longitudinal mid-axis, a lateral temperature gradient of at most 2 K/cm measured perpendicular to the longitudinal mid-axis is adjusted and maintained in this range. The bulk SiC single crystal has a large facet region.
US08865321B2 Organic electroluminescent devices
The present invention relates to electronic devices, in particular organic electroluminescent devices, which comprise compounds of the formula (1), and to the corresponding compounds and to the use thereof in organic electroluminescent devices.
US08865308B2 Forced entry resistant transparent laminate
A forced entry resistant transparent laminate comprising a combined rigid and energy absorbing laminate panel assembly having a strike side surface opposing a direction of an anticipated threat, bonded together with a transparent, ether-based thermoplastic elastomer interlayer interposed between glass or polymer layers, where the thermoplastic elastomer interlayer further includes a transparent polyurethane having an ultra-high modulus of elasticity. The energy absorbing layers include a transparent, quasi-thermoset cast from an aliphatic urethane bonded to the rigid laminate layers.
US08865307B2 Method and system for producing graphene and functionalized graphene
This disclosure includes a process that unexpectedly can produce very inexpensive graphene, functionalized graphenes, and a new compound called graphenol in particulate or dispersions in solvents. The process can also produce graphene layers on metallic and nonmetallic substrates. Further, the graphenol, functionalized graphenes, and graphene can be utilized to form nanocomposites that yield property improvements exceeding anything reported previously.
US08865303B2 Highly reflective roofing system
A cool roofing system includes highly reflective calcined kaolin particles having a solar reflectance of 80% to 92%. When applied to a roofing substrate, the highly reflective kaolin particles produce a roofing system having a solar reflectance greater than or equal to 70%.
US08865300B2 Curved bullet proof glass made of glass, glass-ceramic or ceramic mechanically curved on the strike-face layer
A curved bullet-proof composite comprising: a glass or glass-ceramic external strike-face layer having been subjected to an ion exchange process and which is mechanically curved; at least one glass or glass-ceramic intermediate layer; an internal plastic layer; and an adhesive material between the strike-face layer, the at least one intermediate layer and the internal plastic layer.
US08865299B2 Multi-layered acrylic retardation film and fabrication method thereof
The present invention provides a retardation film that comprises a) a first acrylic resin layer; and b) a second acrylic resin layer that is layered on at least one side of a) the first acrylic resin layer and comprises an acrylic resin and 1 to 20 parts by weight of rubber component based on 100 parts by weight of the acrylic resin. The retardation film according to the present invention has excellent optical transparency, haze, brittleness, mechanical strength, heat resistance, durability, and the like.
US08865297B2 Heterogeneous surfaces
Condensation can be an important process in both emerging and traditional power generation and water desalination technologies. Superhydrophobic nanostructures can promise enhanced condensation heat transfer by reducing the characteristic size of departing droplets via a surface-tension-driven mechanism. A superhydrophobic surface can include a heterogeneous surface.
US08865295B2 Process for the preparation of a multilayer structure comprising a substrate, a crystalline organic barrier layer, and a printed pattern; and products obtained
The invention provides a process for making a multilayer structure with a printed pattern by providing a film substrate having a crystalline organic compound layer, wherein the substrate optionally has a metal or metaloxide layer between the film substrate and the organic compound layer; applying a printed pattern via a plurality of printing rolls wherein the following steps are performed: optionally, applying as a first layer a primer over the whole surface, applying one or more ink layers on the film to obtain a printed pattern, and optionally, applying a cover varnish to obtain a film substrate with a crystalline organic compound layer and a printed pattern. The invention further relates to a laminate comprising a multilayer structure and a plastic film; the laminate preferably comprises a primer substantially covering the whole surface of the organic compound layer, on which primer the print is present.
US08865294B2 Thermoplastic multi-ply film with metallic appearance
Laminated multi-ply films where one film layer is substantially unpigmented and the other film layer is substantially pigmented can provide a metallic appearance when the substantially unpigmented film layer is cold stretched either prior to lamination or during the lamination step. This surprising result provides an inexpensive way to produce films with a metallic appearance. Trash bags having an inner bag and an outer bag laminated together may be formed according to this process.
US08865291B2 Plasma-resistant member
A plasma-resistant member according to the present invention includes a base member formed of a silicon nitride sintered body, an aluminum nitride sintered body, an alumina sintered body, or a silicon carbide sintered body; and a thin film formed on a surface of the base member and composed of an yttrium compound or a spinel, wherein the thin film has, in a surface of the thin film, a plurality of projections for supporting a wafer, and a ratio a2/a1 of a film thickness a2 of portions of the thin film that include the projections to a film thickness a1 of portions of the thin film that do not include the projections satisfies 1
US08865290B2 Fastening clip assembly
A fastening clip assembly configured to securely fasten to a mounting stud of a panel includes a main clip and a tapered member, such as a tapered locking pin. The main clip may include a central column defining a central passage. The central column may include a ledge. The tapered locking pin integrally connects to the central column through at least one flash joint integrally connected to the main clip proximate the ledge. The said tapered locking pin is configured to move into the central passage in order to securely fasten the assembly to the mounting stud.
US08865289B2 Incrementally stretched films with increased tear resistance and methods for making the same
Methods of incrementally stretching thermoplastic films in the machine direction include elongating the films in the machine direction without reducing the films' machine-direction tear resistance. In one or more implementations, methods of incrementally stretching thermoplastic films include reducing the gauge of the films without reducing the films' machine-direction tear resistance. The methods can involve cold stretching the films and imparting transverse-direction extending linear rib pattern into the film. The linear ribs can have alternating thick and thin gauges. Incrementally stretched thermoplastic films can have a machine-direction tear resistance that is equal to or greater than the machine-direction tear resistance of the film prior to stretching.
US08865284B2 Fabric mosaic element and method for making the same
Fabric mosaic element characterized in that it comprises a plurality of tesserae including, in a sequence and mutually bonded, a fabric, an anti-fraying material and a flexible layer constituted of a natural or man-made material, of a density ranging between 150 kg/m3 and 350 kg/m3, said tesserae being fixed to a of thermoplastic material layer in correspondence of the respective flexible layer.
US08865282B2 Protective cover plate
A protective cover plate mainly comprises a substrate, a printing layer, an ultraviolet layer and an adhesive layer, wherein the printing layer is disposed at a side surface of the substrate. The printing layer is formed with at least a pattern. The pattern protrudes the substrate to form a segmental difference surface. The ultraviolet layer is disposed to another side surface of the printing layer relative to the substrate, and the ultraviolet layer is disposed with at least a filling portion. The filling portion can be relatively located near the pattern to fill the segmental difference surface of the pattern to flat the surface. A side of the ultraviolet layer is disposed with the adhesive layer. The plate can be adhered to the article by utilizing the adhesive layer. The protective cover plate does not only have flat appearance but also achieves dustproof and dirt prevention efficacies.
US08865280B2 Fuel hose and method for producing the same
A fuel hose according to an aspect of the present disclosure includes: a tubular inner rubber layer; a resin layer formed on an outer circumferential surface of the inner rubber layer; and an outer rubber layer formed on an outer circumferential surface of the resin layer, wherein the inner rubber layer includes a rubber material containing the following Components (A), (B) and (C), the outer rubber layer includes a rubber material containing the following Components (A′), (B) and (C′), and the resin layer includes a resin material containing the following Component (X) as a main component: (A) acrylonitrile-butadiene rubber, (A′) blend rubber containing acrylonitrile-butadiene rubber and acrylic rubber, (B) a sulfur vulcanizing agent, (C) an amine catalyst to form bonding points, (C′) an amine catalyst to form bonding points, which contains 1,5-diazabicyclo(4.3.0)non-5-ene salt (DBN salt), and (X) tetrafluoroethylene-perfluoro(alkylvinylether)-chlorotrifluoroethylene copolymer.
US08865274B2 Liquid crystal display device, alignment film, and methods for manufacturing the same
A liquid crystal display device is provided, including a liquid crystal layer interposed between a first display panel and a second display panel; and an alignment film formed on at least one of the first and second display panels, the alignment film including first polysiloxanes and second polysiloxanes disposed on the first polysiloxanes, wherein a first portion of silicon atoms of the second polysiloxanes are bonded to vertical functional groups interacting with liquid crystal molecules in the liquid crystal layer, and to first pre-tilting functional groups aligning the liquid crystal molecules in the liquid crystal layer to be tilted with respect to at least one of the first and second display panels by being cross-linked. The bonding structure of the first and the second polysiloxanes being different.
US08865273B2 Photoalignment compound, photoalignment composition, display substrate having an alignment layer, and method for manufacturing the display substrate
A photoalignment compound is represented by the following Chemical Formula 1, wherein “x” represents an integer in a range of 1 to 4, each of R1 and R2 represents —(CH2)n—, “n” represents an integer in a range of 1 to 6, at least one of the (—CH2-)s in R1 is replaceable with R3 represents —(CH2)mCH3, “m” represents an integer in a range of 1 to 12, each hydrogen atom of R3 is replaceable with F or Cl, R4 represents an amino group, aniline group, carboxy group, hydroxyl group, cyano group, alkylene group, or functional groups being represented by the following Chemical Formulas 2, 3, 4, or 5, each hydrogen atom of Chemical Formula 1 is replaceable with —O(CH2)kCH3, —(CH2)kCH3, F, or Cl, and “k” represents an integer in a range of 1 to 3, or 0.
US08865272B2 Liquid crystal displays
In an embodiment of the present disclosure, a liquid crystal display is provided. The liquid crystal display includes an upper substrate, a lower substrate opposite to the upper substrate, and a liquid crystal layer disposed between the upper substrate and the lower substrate, wherein the liquid crystal layer includes a first chiral compound and a second chiral compound, and the first chiral compound and the second chiral compound are enantiomeric and separated from each other.
US08865270B2 Method for manufacturing power storage device
The power extraction efficiency of a nonaqueous electrolyte secondary battery such as a lithium ion battery is improved. A material having magnetic susceptibility anisotropy such as an olivine type oxide including a transition metal element is used for active material particles. The active material particles and an electrolyte solution are mixed to form a slurry. The slurry is applied to a current collector, and then the current collector is left in a magnetic field. Thus, the active material particles are oriented. With the use of active material particles oriented in such a manner, the power extraction efficiency can be improved.
US08865268B2 Method and apparatus
A method and apparatus, the method including: forming a recess in a graphene layer wherein the recess creates a boundary between a first portion of the graphene layer and a second portion of the graphene layer; depositing electrically insulating material within the recess; and depositing an electrically conductive material over the insulating material.
US08865267B2 Coated board of wood-based material and a method of producing same
A method for coating a board of wood-based material, comprising the steps of providing a board of wood-based material; applying a first liquid coating; applying at least a second liquid coating onto the still wet first coating, so that a partial mixture of the coatings takes place; curing the applied coatings by means of radiation, wherein the coatings are selected so that the cured resultant coating has a hardness gradient wherein the hardness of the resultant coating decreases with increasing depth viewed from the surface of the resultant coating.
US08865264B2 Plasma coatings and method of making the same
A method of coating a substrate surface. The method includes plasma spraying a direct-spray component onto a substrate surface, and plasma spraying an over-spray component onto the substrate surface. The direct-spray and over-spray components form a plasma coating surface contacting at least a portion of the substrate surface.
US08865263B2 Papermaking additives for roll release improvement
Compositions and methods for reduction in adhesion between wet paper web and roll surfaces in papermaking process are disclosed. The method is particularly useful for improvements in press section roll release.
US08865259B2 Method and system for inline chemical vapor deposition
Disclosed are an inline chemical vapor deposition method and system for fabricating a device. The method includes transporting a web or discrete substrate through a deposition chamber having a plurality of deposition modules. A buffer layer, a window layer and a transparent conductive layer are deposited onto the substrate during passage through a first deposition module, a second deposition module and a third deposition module, respectively. Advantageously, the steps for generating the buffer layer, window layer and transparent conductive layer are performed sequentially in a common vacuum environment of a single deposition chamber and the use of a conventional chemical bath deposition process to deposit the buffer layer is eliminated. The method is suitable for the manufacture of different types of devices including various types of solar cells such as copper indium gallium diselenide solar cells.
US08865256B2 Tire surface printing method and tire printing device
A tire printing device includes a printer head (2), positioned near a rotating tire (1), that ejects and applies coating material, an unevenness detection sensor (3) that detects a predetermined raised/recessed character on the surface of the rotating tire (1) and a PC (10) that sets the origin of rotation of the tire (1) based on a signal detected by the unevenness detection sensor (3) and synchronizes the operation start time of the printer head (2) with the origin of rotation in order to maintain a constant relationship between the position of the raised/recessed character and the position of application of the coating material. Desired printing is performed by the printer head (2) ejecting and applying the coating material onto a surface of the rotating tire (1) after the rotating tire is mounted on a rim and inflated to a regular shape by being applied with an internal pressure.
US08865253B2 Method of coloring surface of zirconium-based metallic glass component
A method of coloring a surface of a zirconium-based metallic glass component that includes the step of imparting interference colors by carrying out an anodizing process using an alkaline solution to form a film having a thickness of 300 nm or less on the surface of the zirconium-based metallic glass component.
US08865247B2 Needle coating formulation having lubricity and durability
A medical device coated with a novel lubricious coating is disclosed. The coating contains a pre-oxidized hydrophobic polymer, a cross-linking agent, a silicone or siloxane polymer, a slip agent and a catalyst.
US08865245B2 Edible fat powders
The invention relates to edible fat powders having a full width at half maximum of the first order long spacing X-ray diffraction peak of 0.17 to 0.80 degrees and a free flowing density of 10 to 350 g/l; with the proviso that when the free flowing density is equal to or greater than C, the full width at half maximum is equal to or greater than ((A*free flowing density)+B), wherein A is 0.0005625, B is 0.213 degrees and C is 90 g/l. The invention further relates to a method of preparing a fat continuous spread comprising the use of such edible fat powder.
US08865241B1 Mutant bacterial strains of the genus Sphingomonas deficient in production of polyhydroxybutyrate and a process of clarification of sphingans and compositions thereof
The invention relates to mutant strains of the genus Sphingomonas which have a mutation in at least one gene encoding a protein involved in polyhydroxybutyrate (“PHB”) synthesis that allows the mutant strains to produce PHB-deficient Sphingans. The invention is also directed to a process for preparing a clarified Sphingan solution comprising heating aqueous Sphingan solution, in particular PHB-deficient Sphingan solution, to a clarification temperature of about 30° C. to about 70° C., and treating the solution with a clarification agent and enzymes. In addition, the invention is directed to a food or industrial product comprising a PHB-deficient and/or clarified Sphingan. One particular embodiment of the invention is directed to a clarified, PHB-deficient high-acyl gellan and the processes of making thereof.
US08865239B2 Humectant infused jerky treat
The invention relates to compositions and methods for making human consumable jerky treats. The invention provides moist, flavorful jerky treats and methods for making such treats.
US08865238B2 Bacterium
The present invention relates to a bacterial cell with texturizing property, starter cultures comprising the cell, and dairy products fermented with the starter culture.
US08865235B2 Microbicidal and antiparasitic compositions
Pharmaceutical or dermo-dermo-cosmetic compositions for topical and intravaginal application for treatment of human and veterinary affections caused by anaerobic organisms or parasites comprising quassinoids or plant extracts containing these phytochemicals, in effective amounts. Such compositions can be administered topically or intravaginally to patients in need thereof in various pharmaceutical dosage forms.
US08865234B1 Topical pain reliever
Analgesic formulations to be applied topically that are reported to relieve moderate to severe pain due to tendonitis, fibromyalgia, shingles, insect bites and bee stings, ACL, arthritis, and sinus headaches. In many cases, test subjects report immediate pain relief with a single application and complete pain elimination with only a few applications. The formulations are in a coconut oil base which is skin friendly. The primary active ingredient is wrightia tinctoria, which when combined with other ingredients, causes the formulation to exhibit a synergistic effect on pain relief unexpected from using the ingredients alone or in combination.
US08865225B2 Composition comprising a solid state hypothiocyanite salt of a cation
A solid composition is provided herein comprising at least one hypothiocyanite salt (OSCN—) of a cation in an amorphous and/or crystalline powder form. Also provided herein are methods of making the composition and methods of treating various conditions, such as airborne infection, lower respiratory tract infection or upper respiratory tract infection.
US08865224B2 Allogeneic cellular immunotherapy for opportunistic infection
A method for stimulating the immune system in immunocompromised patients in order to treat opportunistic infection. The method involves the infusion of intentionally mismatched allogeneic cells. In order to prevent graft vs. host disease complications, the allogeneic cells can be irradiated prior to infusion.
US08865220B2 Method for controlled release of parathyroid hormone from encapsulated poly(lactic-glycolic)acid microspheres
The present invention provides a method for producing a controlled release microsphere with mean average size greater than 50 μm, comprising preparing a water-in-oil (w/o) emulsion comprising an inner aqueous layer containing a pharmaceutically effective amount of a biologically active polypeptide with activity similar to parathyroid hormone, and an oil layer containing a polymer substance of poly(lactic-co-glycolic acid) (PLGA), then adding the w/o emulsion into aqueous polyvinyl alcohol (PVA) solution to form a water-in-oil-in-water (w/o/w) double emulsion and then desorbing the solvent in the oil layer. The present invention also provides a controlled release microsphere prepared by the method and use thereof.
US08865218B2 Microencapsulation process of sertoli cells, microcapsules obtained and use for treatment of type I diabetes mellitus
The invention relates to the use of Sertoli cells (SC) microencapsulated into hydrogel-based microcapsules, for the prevention and/or treatment of Type 1 diabetes mellitus (T1DM) and to a process for producing microcapsules, preferably shaped as microspheres.
US08865206B1 Surface modified multilayered nanostructures for dermal delivery
Dermal delivery is best suited for the various skin diseases or disorders. However, the stratum corneum limits the permeation of number of suitable pharmaceutical agents for dermal delivery. Certain embodiments of the present invention include surface modified multilayered nanostructures. The modification was completed by using fatty acids enabling delivery of a significant amount of one or more pharmaceutical agent(s) into deeper layers of the epidermis and dermis to treat skin diseases or disorders. Each active pharmaceutical agent can be encapsulated into the separate layers of the nanostructures.
US08865200B2 Sustained release compositions containing progesterone receptor modulators
Disclosed are sustained release compositions for vaginal or transdermal administration that contain a progesterone receptor modulator such as CDB-2914 (also referred to as VA-2914), and methods of using them for long term contraception or therapeutic purposes. Also disclosed are methods for making the compositions.
US08865197B2 Food formulation for aquatic animals with integrated targeted delivery of bioactive agents
An encapsulated formulation for food and bioactive agent delivery to aquatic animals includes various combinations of nutrients, a digestion enhancer, bioactive agents, and a local absorption enhancer. The bioactive agents and absorption enhancer may be encapsulated within a delay layer for targeted release at an area of the digestive tract distinct from the region of nutrient release. The bioactive agents and absorption enhancer may be coated with a sticky coating so that they tend to adhere to the inner surfaces of the wall of the digestive tract, thereby localizing their release and enhancing their effect. Instead of bioactive agents themselves, precursors may be delivered so as to generate the bioactive agents locally. The encapsulated precursors of a specific bioactive agent are separately contained in capsules which themselves can be adhesive to one another.
US08865196B2 Antimicrobial compositions
An environmentally- and user-friendly, aqueous antimicrobial solution comprising effective amounts of hydrogen peroxide, glycolic acid, and at least one antimicrobially-active solvent chosen from benzyl alcohol and phenoxyethanol; concentrated versions of same; kits that can be used to make same; wipes containing same; and the use of same in a method of antimicrobial treatment of a surface contaminated with a microorganism (e.g. bacterial or fungal spore such as C. Difficile).
US08865192B2 Flavor oils with reduced sulfur content and use in oral care compositions
The present invention relates to flavor oils including mint-, fruit- and spice-type flavors that are specially processed to substantially eliminate low-molecular weight sulfur compounds, in particular dimethyl sulfoxide (DMSO), which has been found to be the main precursor of malodorous species such as dimethyl sulfide and methyl mercaptan. These malodorous species are produced via oxidation-reduction reactions involving such sulfur-containing compounds present in flavor oils. A preferred processing method is an aqueous-washing process, which has advantages of being simple, inexpensive and easy to implement while importantly avoiding the problems of typical processes including non-selective removal of desirable components and subjecting the flavor oils to extreme conditions that may destroy other components and result in undesirable changes in flavor or odor character. Other processing methods to selectively remove non-desired components include (1) distillation to remove polar low boiling point components, (2) filtration through adsorbents selective for sulfur compounds, (3) countercurrent extraction and (4) column chromatography. The processing methods may optionally be followed by reengineering to add back desired components that may have been removed or altered during the processing. The specially processed flavor oils are particularly useful in oral care compositions comprising components with chemical reducing capability such as stannous ions, which react with the sulfur-containing compounds to produce malodorous products.
US08865190B2 Pharmaceutical compositions for the coordinated delivery of NSAIDs
The present invention is directed to drug dosage forms that release an agent that raises the pH of a patient's gastrointestinal tract, followed by a non-steroidal anti-inflammatory drug. The dosage form is designed so that the NSAID is not released until the intragastric pH has been raised to a safe level. The invention also encompasses methods of treating patients by administering this coordinated release, gastroprotective, antiarthritic/analgesic combination unit dosage form to achieve pain and symptom relief with a reduced risk of developing gastrointestinal damage such as ulcers, erosions and hemorrhages.
US08865188B2 Methods and compositions for controlling assembly of viral proteins
Provided herein are methods and compositions for controlling assembly of modified viral core proteins, for example, into a viral capsid or a nanocage. In some embodiments, the disclosed modified viral core proteins comprise at least one mutation or modification that can substantially prevent assembly of the viral core proteins until assembly is desired. In some embodiments, assembly of the viral core proteins may be triggered, for example, by contacting the viral core proteins with a reducing agent and/or by reducing the concentration of a denaturant. The viral core proteins may self-assemble to form a viral capsid or nanocage.
US08865187B2 Compositions comprising lecithin oils and NSAIDs for protecting the gastrointestinal tract and providing enhanced therapeutic activity
A novel pharmaceutical composition is provided by which nonsteroidal anti-inflammatory drugs (NSAIDs) are added directly to phospholipid-containing oil such as lecithin oils or to a bio-compatible oil to which an phospholipid has been added to make a NSAID-containing formulation that possess low gastrointestinal (GI) toxicity and enhanced therapeutic activity to treat or prevent inflammation, pain, fever, platelet aggregation, tissue ulcerations and/or other tissue disorders. The composition of the invention are in the form of a non-aqueous solution, paste, suspension, dispersion, colloidal suspension or in the form of an aqueous emulsion or microemulstion for internal, oral, direct or topical administration.
US08865185B2 Methods of use for HSV-1 and HSV-2 vaccines
This invention provides methods of treating, suppressing, inhibiting, reducing an incidence, reducing the pathogenesis of, ameliorating the symptoms of, or ameliorating the secondary symptoms of a primary or recurring Herpes Simplex Virus (HSV) infection, or prolonging the latency to a relapse of an HSV infection, and disorders and symptoms associated with same and inducing an anti-HSV immune response in a subject comprising the step of contacting the subject with a composition comprising a mutant HSV strain comprising an inactivating mutation in a Us8 gene, followed by a second contacting with the composition.
US08865182B2 Adenoviral-based vectors
The present invention provides replication competent adenoviral vectors capable of expressing antigens from infectious pathogens, such as influenza virus. The adenoviral vectors can be used to vaccinate subjects against the infectious pathogens. The adenoviral vectors comprise heterologous sequences encoding the antigens. The heterologous sequences can be inserted into various locations in the adenoviral vectors, including in or near specific E3 deletions and/or integrated into the adenoviral hexon coding region. The adenoviral vectors can be derived from any adenoviral serotype, particularly an Ad4 or Ad7 serotype.
US08865179B2 Aptameric IgE peptides in a protein scaffold as an allergy vaccine
A method is disclosed wherein an antigenic B-cell epitope is discovered by in vitro transcription and translation of pre-determined sequence on thermostable protein scaffolds detected by antibodies to a native protein. Immune reactivities of IgE B-cell epitopes from pre-determined IgE sequences from the constant region, engaged in binding to high affinity IgE Fc receptors, placed in a loop of green fluorescent protein (GFP) were shown immuno-reactive with anti-IgE. Moreover, the antigenic B-cell epitope can be further optimized by molecular evolution, selected by conformer antibody and receptor on solid phase via ribosome display. Alternatively, a random aptameric antigenic sequence inserted into a loop of the protein scaffold, mimicking a pre-determined sequence of a native protein, can be selected by solid phase conformer antibody and receptor via ribosome display. High affinity binding of B-cell epitopes selected from the random aptameric library with antibodies to native pre-determined B-cell epitope of a native protein can be optimized by molecular evolution with error-prone RT-PCR by ribosome display.
US08865177B2 Pressure sore treatment
Methods for treating a pressure sore or for preventing development of a pressure sore by local administration of a Clostridial toxin, such as a botulinum neurotoxin, to a pressure sore or to a pressure point, or to the vicinity thereof.
US08865176B2 Methods and compositions for generating bioactive assemblies of increased complexity and uses
The present invention concerns methods and compositions for making and using bioactive assemblies of defined compositions, which may have multiple functionalities and/or binding specificities. In particular embodiments, the bioactive assembly is formed using dock-and-lock (DNL) methodology, which takes advantage of the specific binding interaction between dimerization and docking domains (DDD) and anchoring domains (AD) to form the assembly. In various embodiments, one or more effectors may be attached to a DDD or AD sequence. Complementary AD or DDD sequences may be attached to an adaptor module that forms the core of the bioactive assembly, allowing formation of the assembly through the specific DDD/AD binding interactions. Such assemblies may be attached to a wide variety of effector moieties for treatment, detection and/or diagnosis of a disease, pathogen infection or other medical or veterinary condition.
US08865175B2 Increasing anti-IL-1α antibodies in a subject
Method of detecting individuals at risk for atherosclerosis and related vascular diseases involving the detection of IL-1α autoantibodies, as well as therapeutic methods to prevent or treat atherosclerosis and related vascular disease by administering a pharmaceutical composition comprising IL-1α autantibodies.
US08865172B2 Method for reducing the number of unwanted molecules in bodily fluids
A method for reducing the number of selected antibodies in a subject's blood, the method comprising removing blood from the subject, passing the blood along an enclosed pathway, wherein the pathway comprises one or more semi-permeable hollow fibers with one or more membranes having surfaces positioned substantially perpendicular to the length of the one or more hollow fiber and antigens specific for the antibodies immobilized on the one or more membranes, returning the treated blood to the internal circulation of the subject, wherein the returned treated blood has a reduced number of selected antibodies compared to before treatment.
US08865168B2 Methods and compositions to regulate hepcidin expression
The present invention provides new systems and strategies for the regulation of iron metabolism in mammals. In particular, methods of using agonists and antagonists of TGF-β superfamily members to modulate the expression or activity of hepcidin, a key regulator of iron metabolism, are described. The inventive methods find applications in the treatment of diseases associated with iron overload, such as juvenile hemochromatosis and adult hemochromatosis, and in the treatment of diseases associated with iron deficiency, such as anemia of chronic disease and EPO resistant anemia in end-stage of renal disease. The present invention also relates to screening tools and methods for the development of novel drugs and therapies for treating iron metabolism disorders.
US08865165B2 Monoclonal antibody against group 2 allergen of Dermatophagoides pteronyssiuns, hybridoma cell line producing thereof, strip, kit and method using said monoclonal antibody for dust mite assay
This present invention discloses a monoclonal antibody which specifically recognizes and binds to a epitope of group 2 allergen of Dermatophagoides pteronyssiuns, usually named Der p 2, and a hybridoma cell line producing thereof. Furthermore, this invention also discloses a strip, kit and method utilizing said monoclonal antibody for the detection of the presence of dust mite allergens and the calculation of dust mite number in the environment.
US08865164B2 Detecting complement activation
Methods of detecting complement activation including steps of detecting in a sample from a subject a level of iC3b wherein the detecting involves specific interaction between the iC3b and a non-cross-reactive antibody thereto, comparing the detected level with a reference level, which reference level is within a range of about 10 ng/ml to about 5,000 ng/ml, wherein determination that the detected level is above the reference level indicates that the subject is suffering from or susceptible to undesirable and/or pathologic complement activation, and administering treatment to treat undesired complement activation if the detected level is above the reference level. Other methods of detecting complement activation with or without measuring iC3b are also provided.
US08865163B2 Pharmaceutical compositions and methods of treatment
The present invention provides pharmaceutical compositions comprising an activated potentiated form of an antibody to human cannabinoid receptor and use in the treatment of obesity and related metabolic disorders. The present invention further provides pharmaceutical compositions comprising an activated potentiated form of an antibody to human cannabinoid receptor and activated potentiated form of an antibody to protein S-100 for use in the treatment of addiction to psychoactive substances.The present invention provides methods for treating obesity and related metabolic disorders and substance abuse.
US08865161B2 Adsorbent for an oral administration, and agent for treating or preventing renal or liver disease
An adsorbent for an oral administration, comprising a surface-modified spherical activated carbon wherein an average particle diameter is 50 to 200 μm, a specific surface area determined by a BET method is 700 m2/g or more, a bulk density is less than 0.54 g/mL, a total amount of acidic groups is 0.30 to 1.20 meq/g, and a total amount of basic groups is 0.20 to 0.9 meq/g is disclosed. The adsorbent for an oral administration has a high adsorbability, and is capable of adsorbing a large amount of toxins during a retention period in an intestine, and of remarkably reducing an amount of urinary proteins excretion.
US08865159B2 Treatment of tumors by ablating bone marrow-derived endothelial progenitor cells
This invention provides methods of treating tumors and other conditions characterized by abnormal neoangiogenesis by inhibiting bone marrow-derived endothelial progenitor cells.
US08865158B2 Bacteriophages for reducing toxicity of bacteria
A genetically modified bacteriophage is disclosed which comprises: (i) an exogenous polynucleotide which encodes an agent which reduces the toxicity of a bacterium; and (ii) an exogenous polynucleotide which encodes a selectable marker. Uses thereof and kits comprising same are also disclosed.
US08865153B2 Microorganisms for imaging and/or treatment of tumors
Modified viruses encoding transporter proteins and methods for preparing the modified viruses are provided. Vaccines that contain the viruses are provided. The viruses also can be used in diagnostic methods, such detection and imaging of tumors. The viruses also can be used in methods of treatment of diseases, such as proliferative and inflammatory disorders, including as anti-tumor agents.
US08865149B2 Polymeric reagents comprising a ketone or a related functional group
Polymeric reagents comprising a polymer attached, either directly or through one or more atoms, to a ketone or a related functional group such as ketone hydrate, thione, monothiohydrate, dithiohydrate, hemiketal, monothiohemiketal, dithiohemiketal, ketal, or dithioketal are provided. The polymeric reagents are useful for, among other things, forming polymer-active agent conjugates. Related methods, compositions, preparations, and so forth are also provided.
US08865144B2 Personal care compositions comprising responsive particles
Personal care compositions comprising responsive particles. In one aspect, the responsive particle comprises: (1) a particle core having an interfacial surface, (2) a first polymer having a first property, and (3) a second polymer having a contrasting property. The first polymer and the second polymer are attached at different locations to the interfacial surface of the particle core. In another aspect, the responsive particle comprises: (1) a particle core having an interfacial surface, (2) at least one block co-polymer comprising a first block and a second block, wherein said first block has a first property and said second block has a second property, and (3) optionally, at least one other polymer having a third property. The block co-polymer and the optional other polymer (if present) are attached to the interfacial surface of the particle core, and at least one of the properties contrasts. The personal care compositions also comprise a dermatologically acceptable carrier. Also disclosed are methods of making responsive particles.
US08865138B2 Melanin modification compositions and methods of use
A method for the modification of melanin distribution, and the composition thereof to modify melanin distribution are disclosed. A method for the reduction of melanin distribution, and the composition thereof to reduce melanin distribution are disclosed. A representative composition comprises 4-ethoxybenzaldehyde and one or more additional active agents as well as a pharmaceutically acceptable carrier or excipient. Carriers and excipients may be formulated for topical administration. Compositions may also be formulated for transdermal administration. The compositions may be used for the prevention and treatment of pigmentation disorders, by way of non-limited example, post-inflammatory hyperpigmentation and others. The compositions may be used for lightening skin.
US08865134B2 Chewing gum
Chewing gum comprising an extract from coffee enriched in at least one ester formed between a trans-cinnamic acid and quinic acid wherein the amount of said at least one ester in the gum is 0.1 to 50 wt %.
US08865130B2 Methods and compositions for diagnostic and therapeutic targeting of COX-2
The presently disclosed subject matter provides compositions that selectively bind cyclooxygenase-2 and comprise a therapeutic and/or diagnostic moiety. Also provided are methods for using the disclosed compositions for diagnosing (i.e., by imaging) a target cell and/or treating a disorder associated with a cyclooxygenase-2 biological activity.
US08865126B2 Vitamin-targeted imaging agents
The invention relates to compounds and methods for targeting radionuclide-based imaging agents to cells having receptors for a vitamin, or vitamin receptor binding derivative or analog thereof, by using such a vitamin as the targeting ligand for the imaging agent. The invention provides a compound of the formula for use in such methods. In the compound, V is a vitamin that is a substrate for receptor-mediated transmembrane transport in vivo, or a vitamin receptor binding derivative or analog thereof, L is a divalent linker, R is a side chain of an amino acid of the formula H2NCHRCOOH, M is a cation of a radionuclide, n is 1 or 0, K is 1 or 0, and the compound can be in a pharmaceutically acceptable carrier therefor. The vitamin-based compounds can be used to target radionuclides to cells, such as a variety of tumor cell types, for use in diagnostic imaging of the targeted cells.
US08865125B2 Radioiodination method
The present invention provides a novel method of labelling biological targeting molecules (BTMs) of interest with radioiodine. Also provided are novel radioiodinated BTMs prepared using the method, as well as radiopharmaceutical compositions comprising such radioiodinated BTMs. The invention also provides radioiodinated intermediates useful in the method, as well as in vivo imaging methods using.
US08865117B2 Membrane reactor and process for the production of a gaseous product with such reactor
The invention provides an integrated catalyst and membrane reactor for the production a predetermined gas such as hydrogen. The reactor comprises a gas flow channel, comprising a plurality of alternating catalyst sections and membrane sections, wherein each catalyst section comprises a catalyst bed and each membrane section comprises a plurality of membranes, and wherein the membranes are selectively permeable for the predetermined gaseous species.
US08865115B2 Process for the preparation of nanoparticulate zinc oxide
The present invention relates to a process for the preparation of nanoparticulate zinc oxide in the form of aqueous suspensions or in the form of pulverulent solid. Furthermore, the invention relates to the use of zinc oxide particles and suspensions prepared in this way in cosmetic sunscreen preparations, as stabilizer in plastics, in paints, in coatings and as antimicrobial active ingredient.
US08865111B2 Filmy graphite and process for producing the same
A process for producing a filmy graphite includes the steps of forming a polyimide film having a birefringence of 0.12 or more and heat-treating the polyimide film at 2,400° C. or higher.
US08865110B2 Method for producing graphite film and graphite film produced by the method
A graphite film excelling in heat conductivity, especially, a graphite film of high heat conductivity that even when its thickness is large, would not suffer damage by heat treatment. There is provided a process for producing a graphite film, including graphitizing a raw material film of a polymer film and/or carbonized polymer film, characterized by including (i) holding the raw film in a vessel capable of direct passage of current through voltage application and (ii) applying voltage to the vessel to thereby induce electrification so that graphitization is carried out. There is further provided a process for producing a graphite film, characterized by including the step of holding the raw material film in vessel (A) being electrifiable, subsequently holding the resultant vessel (A) in vessel (B) being electrifiable and effecting current passage through the whole so that graphitization is carried out.
US08865104B2 Method and apparatus for producing high yields of carbon nanostructures
An apparatus for producing high yields of carbon nanostructures is disclosed. The apparatus includes an electric arc furnace and a feeder that directs solid carbon dioxide into an electrical arc generated by the electric arc furnace.
US08865102B2 Carbon material and method for producing same
A method of producing a carbon material which is mainly composed of graphene-containing carbon particles is provided. The method includes a step of producing carbon particles from an organic material by maintaining a mixture containing the organic substance as a starting material, hydrogen peroxide and water under conditions of a temperature of 300° C. to 1000° C. and a pressure of 22 MPa or more. The method further includes a step of heat-treating the carbon particles at a higher temperature than the temperature maintained in the carbon particle producing step. The carbon material produced by the present method has a structure in which substances such as ions can easily enter and leave the graphene structures of the carbon particles, making the carbon material be useful as active materials of secondary batteries and electric double layer capacitors.
US08865096B2 Process for the joint production of sodium carbonate and sodium bicarbonate
A process for the production of sodium carbonate and sodium bicarbonate out of trona, comprising crushing trona ore and dissolving it in a leaching tank containing a solution comprising sodium carbonate and sodium bicarbonate, and an additive selected from the group consisting of: phosphates, phospholipids, carboxylates, carboxilic acids, and combinations thereof, saturated in sodium bicarbonate, in order to produce solid particles suspended in a production solution comprising sodium carbonate, the solid particles containing insoluble impurities and at least 65% by weight of sodium bicarbonate. The solid particles are separated from the production solution containing sodium carbonate. At least part of the production solution containing sodium carbonate is taken out of the leaching tank.
US08865090B2 Micro fluid system support and manufacturing method thereof
A support unit for a microfluidic system includes a first support; a first adhesive layer provided on a surface of the first support; and a hollow filament laid on a surface of the first adhesive layer to have an arbitrary shape and functioning as a flow channel layer of the microfluidic system.
US08865087B2 Steam sterilizer
A sterilizer for sterilizing instruments and devices disposed therein. The sterilizer includes a vessel that has an inner wall and an outer wall. The inner wall defines a sterilization chamber. The outer wall is spaced from the inner wall to define a cavity surrounding the sterilization chamber. A heating element for vaporizing a fluid is disposed in a lower portion of the cavity. A fluid circuit is fluidly connected to the vessel to convey fluid to the cavity, to convey steam from the cavity to the sterilization chamber and to exhaust steam from the sterilization chamber. The fluid circuit includes a conduit that fluidly connects the sterilization chamber to the cavity. A valve is disposed in the conduit for controlling the flow of steam from the cavity to the sterilization chamber. A boiler pump is provided for conveying fluid to the cavity of the vessel.
US08865086B2 Quenching apparatus for a reactor
A quenching apparatus for a reactor is disclosed. The quenching apparatus includes a quenching unit (31) and a mixing unit (41). The quenching unit includes fluid distribution pipes (33) which branch off from a central portion of the quenching unit in radial directions and eject quenching fluid, and one or more first fluid outlets (35) which are formed through the bottom of the quenching unit. The mixing unit includes inclined baffles (43), one or more partitions (42) and a second fluid outlet (45). The inclined baffles are respectively disposed under the first fluid outlets. The partitions partition a space between inner and outer sidewalls of the mixing unit into a plurality of separated spaces in which the inclined baffles are respectively disposed. Fluid guided by the inclined baffles and the partitions is discharged out of the mixing unit through the second fluid outlet.
US08865084B2 Pass-through catalytic substrate including porous ceramic beveled corner portions and methods
A pass-through catalytic substrate can comprise a plurality of porous ceramic substrate walls defining flow channels extending between an inlet end and an outlet end of the catalytic substrate. The pass-through catalytic substrate can include a plurality of porous ceramic beveled corner portions positioned at intersecting corners of the substrate walls within the flow channels. In one example, the porous ceramic beveled corner portions each include a heat capacity less than about 1.38 J/cm3/K. In another example, a catalytic washcoat layer can be provided for coating the porous ceramic substrate walls and the porous ceramic beveled corner portions. Methods for producing a pass-through catalytic substrate also provide porous ceramic beveled corner portions.
US08865080B2 Devices, processes and methods for the production of lower alkyl esters
Embodiments of a process for production of biodiesel from a transesterification reaction of alcohol and triglycerides in a multi-zone tubular reactor is disclosed. Alkyl esters and glycerin are formed from reactants in a reaction mixture as the reaction mixture flows through the zones. The zones include an entrance zone, an exit zone, and an intermediate zone between the entrance and exit zones. The zones are characterized by physical properties such as viscosity, density, composition, and flow regime. The entrance and intermediate zones include static mixers that perform structured mixing that increases the conversion and yield. The degree of mixing provided by the mixers is different in the zones to account for differences in physical properties. Additionally, the product stream from the reactor is passed through a coalescer to increase droplet size of a dispersed glycerin phase, facilitating both rapid separation of the glycerin phase from the biodiesel phase, and increased conversion and yield in a decanter.
US08865074B2 Sample analysis cartridge and sample analysis cartridge reader
A sample analysis cartridge and a sample cartridge reader are provided. In measuring a particular component included in a sample flowing in a microfluidic channel, a numerical value of hematocrit is reflected to thus improve the accuracy of measurement of the particular component.
US08865071B2 Test tape device
A test tape device is disclosed herein for use with a replaceable analytical tape cassette, where the device includes a housing having a cassette compartment covered by a cassette door and a housing opening for sample application, a protective cover that can be moved between a closed position covering the housing opening and a release position allowing access to the housing opening and a door lock for retaining the cassette door in the closed position, wherein the protective cover is coupled with the door lock via an interlocking mechanism, such that the door lock can only be unlocked in the release position of the cover.
US08865065B2 Ozone sanitizing system
A device for sanitizing objects using ozone is disclosed having a container defining an enclosed space and a selectively closeable opening for enclosing the space, an ozone generator, an ozone converter, a controller, and a timer working together to generate a predetermined concentration of ozone within the enclosed space and maintain approximately the same concentration for a predetermined period of time. Also disclosed are assemblies and methods detecting and warning of entrapment within the enclosure and halting ozone production when it occurs. Further disclosed are devices and methods for coupling a maintenance device to the sanitizing system to perform various maintenance operations such as adjusting operational control parameters, and observing conditions within the enclosed chamber in real-time such as temperature, humidity, and ozone concentration.
US08865063B2 Method and apparatus for automated active sterilization of fully implanted devices
The current invention provides this advance in infection control via its unique application of active sterilization to a catheter or implant. While most catheters, and many implants, are passive devices, the current invention will provide an active component as a integral part of the implanted catheter or device to continuously or intermittently sterilize the exposed surfaces/areas of the device. This active sterilization may be accomplished by a variety of mechanisms, including, application of heat, RF, microwave, ultrasound, ultraviolet radiation or other energy capable of sterilizing the device or dislodging any problematic Biofilm that may form. The active sterilization may also employ the pumping of a sterilizing chemical from an attached drug reservoir, the use of electricity or freezing temperatures or any other mechanism for either inhibiting, killing or dislodging any infectious material in contact with the implant. One major advantage of this design is that through the use of a small, battery powered or inductively powered sterilization element, the implanted catheter or device can be effectively sterilized without requiring the standard removal surgery, waiting period, then replacement of the infected device. This is expected to translate into greatly improved outcomes (particularly for devices where infection may be catastrophic, ie a prosthetic knee or hip), greatly improved costs, and greatly improved longevity of susceptible devices (ie IV ports, etc.).
US08865057B2 Apparatus and methods for industrial-scale production of metal matrix nanocomposites
Apparatus and methods for industrial-scale production of metal matrix nanocomposites (MMNCs) are provided. The apparatus and methods can be used for the batch production of an MMNC in a volume of molten metal housed within the cavity of a production chamber. Within the volume of molten metal, a flow is created which continuously carries agglomerates of nanoparticles, which have been introduced into the molten metal, through a cavitation zone formed in a cavitation cell housed within the production chamber.
US08865054B1 Method for manufacturing aluminum-titanate-based ceramic honeycomb structure
A method for manufacturing a ceramic honeycomb structure includes kneading titania particles, alumina particles and binder such that raw material paste including the titania particles, the alumina particles and the binder is prepared, extruding the raw material paste through a die for forming a honeycomb structure such that a body made of the raw material paste and having the honeycomb structure is formed, supporting the body extruded from the die on a holder while moving the holder along extrusion direction at a moving speed relative to an extruding speed of the raw material based on a target diameter size set for the body such that the diameter of the body held by the holder changes to the target diameter size, and sintering the body having the honeycomb structure with the target diameter size such that a ceramic body having the honeycomb structure with the target diameter size is formed.
US08865052B2 Crosslinkable thermoplastic polyurethane
The TPU of this invention contains unsaturation in its polymeric backbone. The unsaturation can be present in the soft segment or in the hard segment or in both the soft and hard segments of the TPU. The TPU can be molded like a thermoplastic, and can be subsequently crosslinked by exposure to electron beam irradiation into thermoset articles having excellent chemical resistance, dimensional stability, set properties, heat resistance, oxidative resistance, and creep resistance. In one embodiment, the TPUs of this invention are the reaction product (1) a hydroxyl terminated intermediate, (2) a polyisocyanate, (3) a saturated glycol chain extender, and (4) a glycol chain extender containing carbon-carbon double bonds, such as the allyl moieties present in trimethylolpropane monoallyl ether. In another embodiment of this invention, the thermoplastic polyurethane which is crosslinkable by e-beam irradiation is comprised of the reaction product of (1) a saturated hydroxyl terminated intermediate, (2) an unsaturated hydroxyl terminated intermediate, wherein the unsaturated hydroxyl terminated intermediate contains carbon-carbon double bonds, (3) a polyisocyanate, and (4) a saturated glycol chain extender.
US08865051B1 Method of making a crosslinked overmolded assembly
A process for making a crosslinked assembly includes steps of: selecting a desired performance parameter for a molded assembly of a first polymeric component and a second polymeric component bonded to the first polymeric component, controlling a first crosslinking percentage for the first polymeric component and a second crosslinking percentage for the second polymeric component independently to provide the desired performance parameter for the assembly, orienting the assembly at an angle between an orientation axis of the assembly and a electron beam direction, exposing the oriented assembly a predetermined number of times (N) to the electron beam operable to deliver a predetermined amount of radiation (R) in the electron beam direction providing a total radiation exposure proportional to (N×R) providing the first component crosslinking percentage and the second component crosslinking percentage, the resulting assembly having the desired performance parameter.
US08865050B2 Method for curing a composite part layup
A composite part layup is cured using a set of tools adapted to hold the layup and which include at least one tool face contacting the layup. Means are provided for heating the tool face to cure the part layup, and for selectively cooling sections of the tool face.
US08865049B2 Method for producing transfer structure and matrix for use therein
There are provided a method for producing a transfer structure, in which detachment between a transfer-receiving material and a matrix can be easily achieved without destroying the fine pattern, the transfer pattern of the matrix is satisfactorily transferred to the transfer-receiving material, and the durability of the matrix is maintained for a long time during repeated transfer; and a matrix for use in the method. A film of a silane coupling agent represented by the following formula (I) is formed on a surface of a matrix having a transfer pattern formed on the surface thereof, a transfer-receiving material is applied thereon to transfer the pattern on the surface of the matrix, and the transfer-receiving material is detached from the matrix to obtain a transfer structure formed of the transfer-receiving material. In formula (I), n represents an integer of 8, 10, 12 or 14; m represents an integer of 3 or 4; and X, Y and Z each independently represent a hydrolyzable group that is a methoxy group, an ethoxy group, a propoxy group, an isopropoxy group, or a halogen atom.
US08865046B2 Imprinting of partial fields at the edge of the wafer
Edge field patterning of a substrate having full fields and partial fields may include patterning using a template having multiple mesas with each mesa corresponding to a field on the substrate. Polymerizable material may be deposited solely between the template and the full fields of the substrate. A non-reactive material may be deposited between the template and partial fields of the substrate.
US08865044B2 Hockey blade with wrapped, stitched core
A construct for a hockey blade that includes a foam core. The foam core includes a first core face, a second core face, and a core edge. A first layer of resin preimpregnated tape is wrapped continuously around the first core face, the core edge and the second core face. A thread is stitched along the first layer of preimpregnated tape. A second layer of resin preimpregnated tape wrapped continuously around the first layer of resin preimpregnated tape.
US08865042B2 Mold for thermoplastic resin molding, cavity mold, and process for producing the cavity mold
A process for producing a heat-insulating cavity mold, characterized by producing two members, i.e., a metallic surface layer member (1) for forming a metallic surface layer (5) of a cavity mold in a mold for thermoplastic resin molding and a cavity mold main body member (9) for forming the cavity mold, forming a heat-insulating layer (10′) on a bonding surface of the member (9), bonding the two members to each other, and subsequently eliminating an unnecessary part (3, 12) of the metallic surface layer member to form the metallic surface layer (5); a heat-insulating cavity mold; and a mold for thermoplastic resin molding which employs the cavity mold. The mold for thermoplastic resin molding is characterized by being a heat-insulating mold comprising: the heat-insulating cavity mold produced by the production technique from a metallic surface layer member made of a metal having low thermal conductivity and a cavity mold main body member made of a metal having high thermal conductivity; and a core mold produced from an SUS steel material for molds.
US08865040B2 Highly conductive composites for fuel cell flow field plates and bipolar plates
This invention provides a fuel cell flow field plate or bipolar plate having flow channels on faces of the plate, comprising an electrically conductive polymer composite. The composite is composed of (A) at least 50% by weight of a conductive filler, comprising at least 5% by weight reinforcement fibers, expanded graphite platelets, graphitic nano-fibers, and/or carbon nano-tubes; (B) polymer matrix material at 1 to 49.9% by weight; and (C) a polymer binder at 0.1 to 10% by weight; wherein the sum of the conductive filler weight %, polymer matrix weight % and polymer binder weight % equals 100% and the bulk electrical conductivity of the flow field or bipolar plate is at least 100 S/cm. The invention also provides a continuous process for cost-effective mass production of the conductive composite-based flow field or bipolar plate.
US08865036B2 Stretch-blowing method and machine
A method for stretch-blowing containers of preforms in a blow-molding station of a blow-molding machine, where a stretching bar is adjusted during a stretching process via an electric servomotor by taking along the preform bottom until it contacts a mold cavity bottom of a blow mold, and where in the final phase or at the end or after termination of the stretching process the force transmitted by the servomotor to the stretching bar is reduced in a controlled manner by a maximum force. A stretch-blowing machine, including an electronic programmable control unit having an input section for programming a fixed or a variable reduction of the force the servomotor transmitted in a final phase or upon termination or after termination of each stretching process to the stretching bar with regard to a maximum force and a fixed or a variable period of time for the force reduction and/or a fixed or a variable force reduction waiting time.
US08865034B2 System for building formwork for concrete stairs and related methods
The present invention provides a system to build formworks for building concrete stairs which is durable and reusable, which can be rapidly mounted and dismantled on site and which is adjustable to a variety of flight of stairs having different widths, rises and pitches. The system comprises (a) at least one side plate which can be releasably secured to a supporting structure on a footing; the side plate defining a side of at least one stair and defining the depth of a tread of said stair; (b) at least one riser member for defining the rise of the at least one stair; the riser member being complementary to the side plate; and (c) means for fastening the riser member to the side plate; wherein the side plate and riser member are reusable.
US08865033B2 Process for producing a dental appliance
The invention relates to a process for producing a dental appliance, the process comprising the steps of a) providing a mixture of a liquid, an inorganic binder precursor being able to undergo a sol/gel reaction and a glass or glass ceramic powder, b) casting the mixture into a mold, c) drying the cast mixture in the mold to obtain a machinable dental appliance, d) optionally machining the dental appliance to obtain a dental workpiece, e) optionally removing the dental appliance or dental workpiece from the mold, f) optionally sintering the dental appliance or dental workpiece and to a dental appliance obtainable by such a process.
US08865029B2 Photochromic polymer and composition comprising photochromic polymer
A photochromic polymer comprising at least one siloxane oligomer and at least two photochromic groups covalently linked to one or both terminuses of the siloxane oligomer and compositions containing photochromic siloxane polymers with narrow polydispersity. The photochromic polymer enhances switching speed in rigid host polymers.
US08865026B2 Thermosetting adhesive
A thermosetting adhesive is configured to include a photoradical generator which generates radicals from irradiation of active energy rays in a thermosetting insulating adhesive component. In a repair method when this thermosetting adhesive is used, a cured matter of the thermosetting adhesive is made soluble or swellable in a predetermined solvent by irradiating the cured matter with active energy rays from the substrate side or the electronic component side prior to separating the electronic component from the substrate, and the cured matter is removed using such solvent. Alternatively, the cured matter of the thermosetting adhesive is made soluble or swellable in a predetermined solvent by irradiating the cured matter with active energy rays after the electronic component has been separated from the substrate, and the cured matter is removed using such solvent.
US08865025B2 Doped conjugated polymers, devices, and methods of making devices
Use of certain materials in hole injection or hole transport layers can improve the operational lifetimes in organic electronic devices. Compositions comprising a doped conjugated polymer, doped with a redox dopant, including iodonium salt, can increase lifetimes. Inks can be formulated and cast as films in organic electronic devices including OLEDs, PHOLEDs, and OPVs. One embodiment provides a composition with a conjugated polymer doped with a redox dopant. Non-aqueous based inks can be formulated. Iodonium salts can be used.
US08865024B2 Lipophilic antioxidant
The present invention relates to a composition containing a first component selected from the group consisting of at least one polyphenol, at least one phenolic diterpene and combinations thereof, (b) at least one glyceride, (c) at least one hydrophilic emulsifier, and (d) at least one hydrophobic emulsifier. Also disclosed is the use of this composition as a lipophilic antioxidant.
US08865022B2 Phosphor particles and making method
Phosphor particles are provided in the form of spherical polycrystalline secondary particles consisting of a multiplicity of primary particles, including a garnet phase having the composition: (AxByCz)3C5O12 wherein A is Y, Gd, and/or Lu, B is Ce, Nd, and/or Tb, C is Al and/or Ga, and x, y and z are in the range: 0.002
US08865014B2 Fire extinguishing composition generating fire extinguishing substance by high temperature sublimation
The present invention relates to a fire extinguishing composition which generate fire extinguishing substance by high temperature sublimation; the fire extinguishing composition comprising a fire extinguishing material which, in a heating process, can sublimate and release a fire extinguishing substance with fire extinguishing properties; the content of the fire extinguishing material is at least 80 wt %. When the fire extinguishing composition is in use, a pyrotechnic agent as a heat source and a power source; and the purpose of fire extinguishing is achieved by: igniting the pyrotechnic agent, generating a large quantity of fire substance from the fire extinguishing composition in the use of high temperature produced by burning pyrotechnic agent, and the fire substance sprays out together with the pyrotechnic agent. When compared with traditional aerosol fire extinguishing systems, gas fire extinguishing systems and water type extinguishing systems, the present invention can provide a more efficient and safer fire extinguishing composition.
US08865012B2 Methods for processing a substrate using a selectively grounded and movable process kit ring
Methods for processing a substrate are provided herein. In some embodiments, a method for processing a substrate may include placing a substrate atop a substrate support disposed beneath a processing volume of a process chamber having a grounded shield surrounding the process volume and a conductive cover ring selectably supportable by the grounded shield; positioning the substrate support in a first position such that the substrate support is not in contact with the conductive cover ring and such that a conductive member electrically coupled to the cover ring contacts the grounded shield to electrically couple the cover ring to the grounded shield; and performing a plasma enhanced etch process on the substrate.
US08865011B2 Method for optimizing the spectral performance of scintillator crystals
The invention provides a method for optimizing the spectroscopy performance of a spectroscopy scintillator by surrounding the scintillator by a reflector material, performing a scan measuring resolution and light output at three or more axial locations on the crystal, where at least one location is close to the PMT or below the crystal (near the PMT) at least one location is at the end away from the PMT of the scintillator), and adjusting the surface finish of the crystal and/or the reflector to obtain equal light output and optimal resolution over the length and different azimuth of the crystal.
US08865008B2 Two step method to fabricate small dimension devices for magnetic recording applications
A two part ion beam etch sequence involving low energy (<300 eV) is disclosed for fabricating a free layer width (FLW) as small as 20-25 nm in a MTJ element. A first etch process has one or more low incident angles and accounts for removal of 70% to 100% of the MTJ stack that is not covered by an overlying photoresist layer. The second etch process employs one or more high incident angles and a sweeping motion that is repeated during a plurality of cycles. Sidewall slope may be adjusted by varying the incident angle during either of the etch processes. FLW is about 30 nm less than an initial critical dimension in the photoresist layer while maintaining a MR ratio over 60% and low RA (resistance×area) value of 1.0 ohm-μm2.
US08864998B1 Bead fluid treatment self-cleaning apparatus and method
Reactive beads interact with a fluid to be treated in a treatment chamber that retains the beads in the chamber and provides a geometry which promotes the fluid flow agitation of the beads to enhance the treatment.
US08864997B2 Method for conducting maintenance on a chromatography column
The present invention relates to methods for conducting maintenance on chromatography columns used in industrial-scale chromatography. In particular, the invention is concerned with safer methods for performing maintenance on such columns, such as cleaning and replacing bed supports, distributors, nozzles, O-rings and other column components, by the use of a handling device to support, lift, carry and manipulate such column components.
US08864996B2 Reduction of conradson carbon residue and average boiling points utilizing high pressure ultrafiltration
This invention relates to a process for producing a product stream with improved reduction of Conradson Carbon Residue (“CCR”) and a reduced average boiling point from a heavy hydrocarbon feedstream utilizing a high-pressure, low-energy separation process. The invention may be utilized to reduce the CCR content and reduce the average boiling point in heavy hydrocarbon feedstreams, such as whole crudes, topped crudes, synthetic crude blends, shale oils, bitumen, oil from tar sands, atmospheric resids, vacuum resids, or other heavy hydrocarbon streams. This invention also results in a process with an improved CCR separation efficiency while maintaining permeate flux rates.
US08864992B2 Phosphate recovery from acid phase anaerobic digesters
A method for recovering phosphate from sewage treatment plants using multi-stage anaerobic digestion includes the treatment of organic acid digest with calcium hydroxide, calcium oxide, and similar compounds to raise pH to near neutral values and precipitate calcium phosphate compounds such as brushite and similar amorphous compounds. The method includes the formation of calcium phosphates on weak-acid ion exchange columns and membranes in contact with organic acid digest. The system includes removal of the calcium phosphate compounds formed by sedimentation, either static or against an upwelling flow, centrifugation, or filtration.
US08864991B2 Module for assembly of a disc filter
The present invention refers to a module (2) for assembly of a filter frame (1) for at least one filter disc (not shown) of a rotatable disc filter, which filter frame is provided for supporting at least two filter segments (not shown), which filter segments together form the outer part of said filter disc. The module (2) comprises an intermediate member (5) intended to beat least partially provided between two adjacent filter segments. According to the invention, the intermediate member (5) comprises at least two parts (6, 7) which are interconnectable with each other in the radial direction of the disc filter
US08864989B2 Upward-type filtering apparatus characterized in laminating method of filtering material
[Object] It is an object of the present invention to provide a filtering apparatus capable of efficiently filtering a large volume of to-be filtered water, in which its filtering material is less prone to be clogged, and even if the filtering material is clogged, it is possible to wash the filtering material.[Solving Means] An upward-type filtering apparatus (1) includes a pressure container (2) and a filtering material (3) made of gravels, filtering sands or particles. The filtering material (3) includes a filtering portion (9) having a plurality of layers which are laminated on one another such that particle diameters thereof are gradually reduced from a lower portion to an upper portion of the filtering portion, and a filtering sand flowing-out preventing portion (10) including a plurality of layers which located on the filtering portion and which are laminated on one another on the filtering portions (9) such that particle diameters thereof are gradually increased from the lower portion to the upper portion of the filtering sand flowing-out preventing portion. The filtering material (3) is charged into the pressure container (2) up to a ceiling thereof, or the filtering material (3) is forcibly pressed down by a retainer member (26) or a weight from above so as to suppress a case where the filtering material (3) floats up. Raw water is sent from a lower portion of the pressure container (2) under pressure of 0.05 MPa or higher.
US08864988B2 Superficially porous particles and methods of making and using same
Disclosed are porous-shell particles, methods of making the particles, and uses thereof. In one aspect, the porous-shell particles are superficially porous particles.
US08864986B1 Pool skimmer basket system
The present invention relates to apparatuses for improving pool skimmers. In some embodiments, the apparatus is a pool skimmer basket system that includes a skimmer basket, a first tube that is attached to the skimmer basket, and a second tube that is adjacent to and rotatable relative to the first tube. The first tube includes a longitudinal slot that feeds water into the skimmer basket. Without being bound by any particular theory, it is believed that the slot increases the velocity of water flowing into the basket and that the system increases the debris-holding capacity and allows one to avoid having to reach through dirty water to remove the skimmer basket.
US08864975B2 Integrated hydroprocessing with high productivity catalysts
Integrated hydroprocessing methods using high activity, low density catalysts are provided. The high activity catalysts allow for lower temperature operation, which reduces catalyst degradation, while the low density of the catalysts means a corresponding reduction in the amount of metal needed to fill a reactor volume. The methods allow for flexible processing of feedstocks with a variety of wax contents.
US08864974B2 Hydrogen generator
A hydrogen generator comprising an enclosure, a series of spaced plates contained within the enclosure and defining between them liquidtight cells, with a plate forming a first wall of each cell of a nobler material than a plate forming a second wall of that cell, and where a first place of the series is an anode arranged to be connected to a power supply and the last plate of the series is a cathode arranged to be connected to a power supply, an inlet to each cell arranged to allow an electrolyte to flow into the cell, and an outlet from each cell arranged to allow an electrolyte and hydrogen gas to flow out of the cell.
US08864973B2 Device for dielectrophoretic manipulation of particles
A device for dielectrophoretic manipulation of suspended particulate matter comprises a plurality of interleaved layers of electrically conductive and non-conductive material wherein at least one channel is defined through a plurality of the interleaved layers of electrically conductive material.
US08864967B2 Device for moving and treating volumes of liquid
A device for displacing a small volume of liquid under the effect of an electric control, including a first substrate with a hydrophobic surface provided with a first electrical conductor, a second electrical conductor positioned facing the first conductor, and a third conductor, forming with the second conductor, a mechanism for analyzing or heating a volume of liquid.
US08864962B2 Electrolyser module
A feed water addition means for an electrolyser module comprising a plurality of structural plates each having a sidewall extending between opposite end faces with a half cell chamber opening and at least two degassing chamber openings extending through the structural plate between the opposite end faces.
US08864960B2 Fluorine gas generating apparatus
A fluorine gas generating apparatus generating a fluorine gas by electrolyzing hydrogen fluoride in molten salt, includes: an electrolytic cell including, above a liquid level of molten salt, a first gas chamber into which a product gas mainly containing the fluorine gas generated at an anode immersed in the molten salt and a second gas chamber separated from the first gas chamber into which a byproduct gas mainly containing a hydrogen gas generated at a cathode immersed in the molten salt; a hydrogen fluoride supply source retaining hydrogen fluoride to be replenished in the electrolytic cell; a refining device trapping a hydrogen fluoride gas evaporated from the molten salt in the electrolytic cell and mixed in the product gas generated from the anode to refine the fluorine gas; and a recovery facility conveying and recovering the hydrogen fluoride trapped in the refining device in the electrolytic cell or the hydrogen fluoride supply source.
US08864957B2 Vanadium oxide thin films
Thin films of vanadium oxide having exceptionally high metal-insulator transition properties are synthesized by RF sputtering. An Al2O3 substrate is placed in a sputtering chamber and heated to a temperature up to about 550 degrees Celsius. Ar and O2 gases are introduced into the sputtering chamber at the flow values of about 92.2 sccm and about 7.8 sccm respectively. A voltage is applied to create a plasma in the chamber. A sputtering gun with vanadium target material is ignited and kept at a power of about 250 W. The phase transition parameters of vanadium dioxide thin films, synthesized by RF sputtering, are modulated by exposing the vanadium dioxide thin film to UV (ultraviolet) radiation so as to induce a change in oxygen incorporation of the vanadium dioxide thin film.
US08864956B2 Multi-component deposition
Ion-enhanced physical vapor deposition is augmented by sputtering to deposit multi-component materials. The process may be used to deposit coatings and repair material on Ti alloy turbine engine parts. The physical vapor deposition may be ion-enhanced electron beam physical vapor deposition.
US08864949B2 System for decontaminating water and generating water vapor
A system and method for decontaminating water and generating water vapor includes introducing contaminated water in to a vessel. The water is moved through a series of rotating trays alternately separated by stationary baffles so as to swirl and heat the water to effect the vaporization thereof to produce a vapor having at least some of the contaminants separated therefrom. The vapor is removed from the vessel for condensing apart from the separated contaminants and the remaining water. The vapor may be passed through a turbine connected to an electric generator. Sensors in a controller may be employed to adjust the speed of rotation of the trays or water input into the vessel in response to the sensed conditions. The treated water may be recirculated and reprocessed through the vessel to increase the purification thereof.
US08864947B2 Vertical pyrolysis equipment for coal material
Disclosed is a vertical pyrolysis equipment for coal material, which comprises an enclosed kiln body with an inlet and an outlet, a flame-gas heating pipelines provided inside the kiln body, coal material propulsion and pyrolysis passage formed between the flame-gas heating pipelines and inner wall of the kiln body, coal pyrolysis gas collecting tube communicated with the coal material propulsion and pyrolysis passage provided on the kiln. The heat generated by flame-gas heating pipelines is conducted and radiated to coal powder in the coal material propulsion and pyrolysis passage. The coal powder sufficiently absorbs the heat and is pyrolyzed into fuel gas, tar gas and coal with high heat value inside the coal material propulsion and pyrolysis passage. The pyrolyzed fuel gas and tar gas are transferred to the gas dedusting-liquifying mechanism outside the kiln through the connecting coal pyrolysis gas collecting tube for collecting, dedusting, separating and high-pressure liquefying.
US08864945B2 Method of making a multi-ply wiper/towel product with cellulosic microfibers
A method of making a multi-ply wiper/towel product with cellulosic microfibers. The method includes compactively dewatering a nascent web that includes at least about 10% fibrillated cellulosic microfibers and has an apparently random distribution of fibers. The dewatered web having the apparently random distribution of fibers is applied to a transfer surface. The web is belt-creped from the transfer surface utilizing a generally planar polymeric creping belt provided with a plurality of perforations through the belt. The belt-creping step occurs under pressure in a belt creping nip defined between the transfer surface and the creping belt. The web is dried to form a dried web that includes a plurality of fiber-enriched hollow domed regions protruding from an upper side of the dried web. The hollow domed regions have a sidewall of a relatively high local basis weight formed along at least a leading edge thereof. The web also has connecting regions of a relatively lower local basis weight forming a network interconnecting the hollow domed regions of the dried web, and transition areas provided with upwardly and inwardly inflected consolidated fibrous regions that transition from the connecting regions into the sidewalls of the hollow domed regions formed along at least the leading edge thereof.
US08864944B2 Method of making a wiper/towel product with cellulosic microfibers
A method of making a multi-ply wiper/towel product with cellulosic microfibers. The method includes compactively dewatering a nascent web that includes at least about 10% fibrillated cellulosic microfibers and has an apparently random distribution of fibers. The dewatered web having the apparently random distribution of fibers is applied to a transfer surface. The web is belt-creped from the transfer surface utilizing a creping belt. The belt-creping step occurs under pressure in a belt creping nip defined between the transfer surface and the creping belt. The web is dried to form a dried web having a plurality of fiber-enriched hollow domed regions protruding from an upper side of the dried web. The hollow domed regions have a sidewall of a relatively high local basis weight formed along at least a leading edge thereof. The web also has connecting regions of a relatively lower local basis weight forming a network interconnecting the hollow domed regions of the dried web, and transition areas provided with upwardly and inwardly inflected consolidated fibrous regions that transition from the connecting regions into the sidewalls of the hollow domed regions formed along at least the leading edge thereof.
US08864943B2 Method for preparing nonionic water-soluble cellulose ether
Provided is a method for preparing nonionic water-soluble cellulose ether having low insoluble content and providing a transparent solution. More specifically, provided is a method for preparing nonionic water-soluble cellulose ether comprising at least the steps of: drying a pulp sheet or pulp chips into which the pulp sheet has been converted, bringing the dried pulp sheet or pulp chips into contact with an alkali metal hydroxide solution to obtain alkali cellulose, draining the alkali cellulose, and reacting the drained alkali cellulose with an etherifying agent.
US08864942B2 Process for producing bleached pulp
A method for producing bleached pulp, including processing unbleached pulp obtained by cooking a lignocellulose substance, followed by treatment with peroxomonosulfuric acid and thereafter by multistage chlorine-free bleaching treatment starting from chlorine dioxide treatment; a method for producing bleached pulp, including processing unbleached pulp for alkali-oxygen bleaching followed by chlorine-free bleaching treatment or totally chlorine-free bleaching treatment to bleach it to a degree of brightness of from 70 to 89%, and further followed by treatment with peroxomonosulfuric acid; and paper produced by the use of the bleached pulp produced according to these production methods, at a papermaking pH of at most 6.
US08864941B2 Separation of lignin from hydrolyzate
A method for the production water insoluble reactive lignin having low sulfur content and lignosulfonates from lignocellulosic material in a batch or continuous process. Lignocellulosic material is fractionated to produce water insoluble native lignin and lignosulfonates in various ratios, while preserving the cellulose and hydrolyzed hemicelluloses using water, ethanol and sulfur dioxide.
US08864940B2 Fruit fiber article and manufacturing thereof
An article including a first fiber derived from a first natural source and a second fiber derived from a fruit. A method of manufacturing an article may include combining a first and second fiber to form a fiber mixture, where the first and second fibers are obtained from discrete materials, and where at least one of the fibers is derived from an edible fruit of a plant. The article may be formed from the fiber mixture.
US08864939B2 Manufacturing feedstock from fruit by-product processing
A system and method of manufacturing a feedstock for producing paper fiber from fruit of a plant may include providing a by-product source inclusive of fiber from the edible fruit after a process for removing a majority of the edible fruit is used to produce a food. One or more treatment processes to brighten the fruit by-product may be performed. The feedstock may be produced from the brightened fruit by-product.
US08864936B2 Apparatus and method for processing substrate
There are provided an apparatus and method for processing a substrate. By using the apparatus and method, plasma processing can be individually performed on each of edge and rear regions of a substrate in a single chamber. The apparatus includes a chamber providing a reaction space; a stage installed in the chamber; a plasma shielding unit installed opposite to the stage in the chamber; a support unit for supporting a substrate between the stage and the plasma shielding unit; a first supply pipe provided at the stage to supply a reaction or non-reaction gas to one surface of the substrate; and second and third supply pipes provided at the plasma shielding unit, the second supply pipe supplying a reaction gas to the other surface of the substrate, the third supply pipe supplying a non-reaction gas to the other surface.
US08864933B2 Substrate treatment apparatus and substrate treatment method
In a substrate treatment method for supplying a coating solution to a substrate with projections and depressions on a front surface thereof to form a coating film on the front surface of the substrate, the coating solution is supplied to the rotating substrate to form a coating film on the front surface of the substrate, and the substrate having the coating film formed thereon is heated to adjust an etching condition of the coating film. Next, the etching solution is supplied to the rotating substrate to etch the coating film, and thereafter the coating solution is supplied to the substrate to form a flat coating film on the front surface of the substrate. Thereafter, the substrate is heated to cure the coating film. This flattens the coating film with uniformity and high accuracy without undergoing a high-load process such as chemical mechanical polishing.
US08864931B2 Mask trimming
A method for etching a dielectric layer is provided. A patterned mask with mask features is formed over a dielectric layer. The mask has isolated areas and dense areas of the mask features. The mask is trimmed by a plurality of cycles, where each cycle includes depositing a deposition layer, and selectively etching the deposition layer and the patterned mask. The selective etching selectively trims the isolated areas of the mask with respect to the dense areas of the mask. The dielectric layer is etched using the thus trimmed mask. The mask is removed.
US08864928B2 Vehicle component fabricated with a hot melt adhesive, and a method and device for the manufacture thereof
A vehicle interior component fabricated using a hot melt adhesive having two base polymers with different melting points, a higher melting point and a lower melting point, for bonding the surfaces of at least two layers of the vehicle interior component. The hot melt adhesive is applied to one of the layers in an activated state at a temperature equal to or greater than the higher melting point and closely bonds with the layer when the adhesive cools to a temperature below the higher melting point. The bond between the two layers is effected at a lower temperature corresponding to the lower melting point to enable removal of the component layers from a mold while still in a warm state.
US08864921B2 Method for annealing a strip of steel having a variable thickness in length direction
A method for annealing a strip of steel having a variable thickness in its length direction with at least thicker and thinner sections, wherein the strip has been cold rolled to form the thicker and thinner sections, one thicker and one thinner section having a length of at most a few meter. The annealing is performed by continuous annealing.
US08864917B2 Group 5 metal source carbide coated steel article and method for making same
One exemplary embodiment includes a process for forming a hard carbide coating onto a low chromium-containing steel article via a chemical deposition process carried out on a particulate mix, in which molybdenum in the form of a compound FeMo or titanium in the form of a compound FeTi, or a mixture of FeMo and FeTi, may be added to the particulate mix used to form the coating.
US08864911B2 Method for removing ionic species from desalination unit
A method for removing ionic species from a desalination unit, comprises: (a) circulating a wash stream in a closed loop comprising a desalination unit and a precipitation unit, the wash stream flowing at a linear velocity of at least 5 cm/second through the desalination unit, the wash stream becoming more saline after passage through the desalination unit; and (b) removing a portion of calcium sulfate from the wash stream by precipitation in the precipitation unit to obtain a supersaturation degree of calcium sulfate in the wash stream entering the desalination unit in a range of from about 1.0 to about 3.0.
US08864906B2 Method for producing silicon wafer
A method for producing a silicon wafer in which occurrence of slip starting from interstitial-type point defects is prevented in a part from the shoulder to the top of the straight cylinder portion of a silicon single crystal when the silicon single crystal is grown by pulling method under growth conditions entering an I-rich region. In order to prevent occurrence of slip in the range from the shoulder (10A) to the top of the straight cylinder portion (10B), the silicon single crystal (10) is pulled under conditions that the oxygen concentration Oi from the shoulder (10A) to the top of the straight cylinder portion (10B) of the silicon single crystal (10) is not lower than a predetermined concentration for preventing slip starting from interstitial-type point defects, more specifically not lower than 9.0×1017 atoms/cm3.
US08864905B2 Use of carboxymethyl chitosans as additives in agglomerating compositions
The present invention belongs to the field of binder compositions for construction, more specifically it relates to the use of carboxymethylchitosan as flocculating additive and setting accelerator in binder compositions of the cement, cement mortar, concrete, grout, stucco and similar type. The invention also relates to binder compositions comprising carboxymethylchitosan, as well as to the method for their preparation.
US08864902B2 Cement clinker, method of manufacturing the same and cement composition
A cement clinker which can be sintered at 1,300 to 1,400° C. which is lower than the conventional sintering temperature and develops excellent strength characteristics such as mortar compression strength.The cement clinker has a total content of C3A and C4AF calculated by Bogue's formulas of 22 mass % or more, a C3S content calculated by Bogue's formula of 60 mass % or more and an iron modulus (I.M.) of 1.3 or less, preferably 1.0 to 1.3. Since the total content of C3A and C4AF is 22 mass % or more, the cement clinker can be sintered at a low temperature and the reduction of strength when a cement composition is cured can be prevented by reducing the iron modulus of the cement clinker.
US08864900B2 Ultrafine nepheline syenite
A useable particulate nepheline syenite having a grain size to provide an Einlehner Abrasive Value of less than about 100 is described. The particulate nepheline syenite is generally free from agglomeration and moisture free. At least 99% of the nepheline syenite particles have a size less than 10 microns. In practice, the nepheline syenite grain size is less than about 5 microns and the distribution profile of the particulate system is generally 4-5 microns.
US08864898B2 Coating formulations for optical elements
Anti-reflective coatings and coating formulations, optical elements and processes for preparing coating formulations and optical elements are described. The coating formulations are formed from at least one alkoxysilane material and at least one high boiling solvent. The coating formulation may be applied using roller coat processes.
US08864897B2 Anti-reflective and anti-soiling coatings with self-cleaning properties
The embodiments of the invention are directed to coatings and their uses. More particularly, the embodiments of the invention are directed to coating compositions that include silane-based precursors that are used to form coatings through a sol-gel process. The coating comprise a dried gel formed from a sol comprising a hydrolyzed alkoxysilane, a hydrolyzed organosilane, and a hydrolyzed organofluorosilane, wherein the hydrolyzed organosilane and the hydrolyzed organofluorosilane are each separately prepared before combining with each other and with alkoxysilane or with another reagent. The coatings so formed are characterized by anti-reflective, abrasion resistant, and anti-soiling properties. The coatings also have extended weatherability to heat, humidity, and protection against ambient corrosives. The coatings formed from the compositions described herein have wide application, including, for example, use as coatings on the outer glass of solar cells.
US08864896B2 Method for forming organic thin film
A method is provided for forming an organic thin film comprising: 1) preparing a hydroxyl group-containing solution by mixing the following (a), (b) and (c) so that the total amount of (A) and (B) in the hydroxyl group-containing solution becomes 0.1 wt% to 80 wt%, and conducting hydrolysis to generate a hydroxyl group-containing compound; a) an adjuvant for forming an organic thin film comprising a metal surfactant (A) having at least one or more hydrolysable group, and a compound (C) that can interact with the metal surfactant in an organic solvent b) a metal surfactant having at least one or more hydrolysable group (B), and c) water 2) preparing a solution for forming an organic thin film by mixing an organic solvent and the hydroxyl group-containing solution of 1); and 3) allowing the substrate to contact with the solution for forming an organic thin film of 2).
US08864895B2 Aqueous silane systems for bare corrosion protection and corrosion protection of metals
The present invention relates to a furnace (12) for melting heated glass using burners (13), wherein the combustion energy is at least partially produced by oxy-fuel combustion, and wherein at least a portion of the oxygen used in the burners (13) is produced by separation, on a ceramic separation membrane (18), from a gaseous mixture including oxygen, the oxygen from the separation being directly channeled into at least one burner (13).
US08864893B2 Bio-based binders for insulation and non-woven mats
An aqueous binder composition is provided that includes a carbohydrate and a crosslinking agent. In exemplary embodiments, the carbohydrate-based binder composition may also include a catalyst, a coupling agent, a process aid, a crosslinking density enhancer, an extender, a moisture resistant agent, a dedusting oil, a colorant, a corrosion inhibitor, a surfactant, a pH adjuster, and combinations thereof. The carbohydrate may be natural in origin and derived from renewable resources. Additionally, the carbohydrate polymer may have a dextrose equivalent (DE) number from 2 to 20. In at least one exemplary embodiment, the carbohydrate is a water-soluble polysaccharide such as dextrin or maltodextrin and the crosslinking agent is citric acid. Advantageously, the carbohydrates have a low viscosity and cure at moderate temperatures. The environmentally friendly, formaldehyde-free binder may be used in the formation of insulation materials and non-woven chopped strand mats. A method of making fibrous insulation products is also provided.
US08864888B2 Oil-water separation device and refining device
This oil-water separation device includes: a supply port (3b) for oily water; a flow passage that causes oily water (X4, X7) supplied from the supply port to flow so that a flow component in a horizontal direction is a main flow component; a floated oil recovery port (F) provided above an upper portion of the flow passage and also at a position spaced from a start end of the flow passage; and a settled oil recovery port (T) provided beneath the flow passage. According to the oil-water separation device, it is possible to separate an oil component from oily water that contains an oil component with higher viscosity.
US08864886B2 Composite getters
A composite getter system is described. The system has NEG materials coated with a polyimide or polyamide based compound.
US08864885B2 Sheet-shaped gas adsorbent and insulating body using same
A sheet-shaped gas adsorbent according to the present invention is composed of at least a thermoplastic resin and copper ion-exchanged ZSM-5 type zeolite (12), and typically represented by, for example, a single layer sheet-shaped gas adsorbent (10), which is configured of dispersing the copper ion-exchanged ZSM-5 type zeolite (12) in the thermoplastic resin sheet (11). Also, the insulating body according to the present invention comprises a sheet-shaped gas adsorbent having the aforementioned configuration, and typically represented by, for example, a configuration, in which a core member and a sheet-shaped gas adsorbent are covered with a sheath member.
US08864883B2 Surface treatments for dessicant media in a water recovery device
A system and method recover water from an ambient airstream. Dehumidification of the airstream is also achieved by removal of the water. A device of the system includes a chamber having a group of trays that hold respective amounts of liquid desiccant in each tray. A foam media absorbs the desiccant to increase an exposed surface of the desiccant to the airstream. Fans and valves are used to control airflow through the device. A charge cycle circulates air through the device to remove water vapor from the airstream. A subsequent extraction cycle removes water collected in the liquid desiccant by a condenser communicating with the chamber. An integral heat exchanger adds heat to the chamber during the extraction cycle. A controller is used to integrate and manage all system functions and input variables to achieve a high efficiency of operational energy use for water collection.
US08864881B2 Slug suppressor apparatus and crude oil stabilization assembly and process therefor
A slug suppressor apparatus comprising an inlet separator capable of gas-liquid separation of full well stream fluid and expanded inclined liquid pipe for dampening slugs. The inlet separator has an inlet for receiving the full well stream fluid, a separated gas outlet in its upper section, and a separated liquid outlet in its lower section. The separated gas outlet and the separated outlet are operationally connected to a gas bypass line and the expanded inclined liquid pipe respectively. The expanded inclined liquid pipe has means for dampening liquid slugs and is connectable to a 3-Phase separator.
US08864879B2 System for recovery of ammonia from lean solution in a chilled ammonia process utilizing residual flue gas
Disclosed herein is a method comprising contacting a residual flue gas stream with a lean solution stream in an appendix stripper; where the residual flue gas stream comprises nitrogen, oxygen and moisture; and where the lean solution stream comprises ammonium, ammonium carbonate, ammonium bicarbonate and ammonium sulfate; forming a vapor phase that comprises ammonia vapor, water vapor, carbon dioxide and nitrogen; forming a liquid phase that comprises water, ammonium sulfate and ammonia; discharging the vapor phase to a capture system; and discharging the liquid phase to a direct contact cooler.
US08864878B2 Heat integration of a cement manufacturing plant with an absorption based carbon dioxide capture process
The present invention relates to methods and systems for improving the utilization of energy in a cement manufacturing plant comprising an absorption based contaminant, e.g. CO2, capture process using thermal regeneration of a liquid absorbent. The methods and systems of the present invention are characterized in that the thermal regeneration of the liquid absorbent is at least partially effected using a hot exhaust gas stream generated in the kiln of the cement manufacturing plant.
US08864877B2 Method for reducing evaporated fuel emission, canister and adsorbent therefor
To provide an adsorbent which achieves a low-emission performance while maintaining the adsorption performance for adsorbing an evaporated fuel component, a canister comprising the adsorbent, and a method for reducing evaporated fuel emission. A second adsorbent (e.g., a granule) filled in a second compartment disposed in a downstream side with respect to a first compartment comprises an activated carbon as an adsorption site and a solid diluent as a non-adsorption site. The adsorbent has a difference in n-butane adsorption volume of not less than 35 g/L between a n-butane vapor concentration of 5% by volume and a n-butane vapor concentration of 50% by volume measured at 25° C., a butane working capacity measured in accordance with ASTM D5228 of not less than 8 g/dL, and a butane desorption rate of not less than 45% when a purge air amount measured in accordance with ASTM D5228 is 30 bed volumes of the adsorbent volume.
US08864875B2 Regeneration of a particulate filter based on a particulate matter oxidation rate
An exhaust gas treatment system for an internal combustion engine is provided comprising an exhaust gas conduit, a particulate filter (“PF”) device, a hydrocarbon source and an electronic control module including operative logic which when implemented. The PF has a filter structure for removal of particulates in the exhaust gas and is selectively regenerated based on an amount of particulates trapped within the filter structure of the PF device. The control module is in communication with the internal combustion engine and the hydrocarbon source, and receives a regeneration signal indicating the amount of particulates trapped within the filter structure of the PF device. The electronic control module includes control logic for monitoring the internal combustion engine prior to a regeneration event. The electronic control module includes control logic for determining a plurality operating parameters of the internal combustion engine based on the monitoring.
US08864871B2 Method for manufacturing copper nanoparticles using microwaves
The present invention relates to a method for manufacturing copper nanoparticles, in particular, to a method for manufacturing copper nanoparticles, wherein the method includes preparing a mixture solution including a copper salt, a dispersing agent, a reducing agent and an organic solvent; raising temperature of the mixture solution up to 30-50° C. and agitating; irradiating the mixture solution with microwaves; and obtaining the copper nanoparticles by lowering temperature of the mixture solution.According to the present invention, several tens of nm of copper nanoparticles having a narrow particle size distribution and good dispersibility can be synthesized in mass production.
US08864864B2 Circular cylinder air filter
A circular cylinder air filter includes an inner cylindrical frame, an outer cylindrical frame, a circular disc, a bonding base and a non-woven fabric cover. The outer cylindrical frame is coaxially arranged around the inner cylindrical frame. The circular disc is fastened to a first end of the inner cylindrical frame and the outer cylindrical frame. The bonding base is fastened to an opposite second end of the inner cylindrical frame and the outer cylindrical frame. A first opening of the bonding base communicates with a first hollow region between the inner cylindrical frame and the outer cylindrical frame. A second opening of the bonding base communicates with a second hollow region within the inner cylindrical frame. The air filter medium is filled into the first hollow region through the first opening. The fabric cover encloses the outer cylindrical frame, circular disc and bonding base to expose the second opening.
US08864863B1 Three-stage separator for a vacuum waste tank system
An air and moisture separator for use with a waste tank and a vacuum source has a canister securable to the waste tank and having an inlet couplable to the waste tank and an outlet couplable to the vacuum source. An air flow path extends through the canister and through at least three different stages of air and moisture separation, including: a first air-turning stage coupled to the inlet; and a second stage of mesh or foam coupled to and subsequent to the first air-turning stage in the air flow path. An annular mesh or foam of greater density defines a third stage subsequent to the second stage, and circumscribes at least a majority of a circumferential perimeter of the mesh or foam of the second stage.
US08864861B2 Nanolaminated coated cutting tool
A cutting tool insert for machining by chip removal includes a body of polycrystalline cubic boron nitride compact (PCBN), either as a solid insert or attached to a backing body, onto which a hard and wear resistant PVD coating is deposited. The coating includes a polycrystalline nanolaminated structure of alternating A and B layers, where layer A is (Ti,Al,Me1)N and Me1 is one or more of the metal elements from group 3, 4, 5 or 6 in the periodic table, layer B is (Ti,Si,Me2)N and Me2 is one or more of the metal elements from group 3, 4, 5 or 6 in the periodic table including Al with a thickness between 0.5 and 10 μm. The insert is particularly useful in metal cutting applications generating high temperatures, e.g., high speed machining of steels, cast irons, super alloys and hardened steels.
US08864859B2 Customized polishing pads for CMP and methods of fabrication and use thereof
The present application relates to polishing pads for chemical mechanical planarization (CMP) of substrates, and methods of fabrication and use thereof. The pads described in this invention are customized to polishing specifications where specifications include (but not limited to) to the material being polished, chip design and architecture, chip density and pattern density, equipment platform and type of slurry used. These pads can be designed with a specialized polymeric nano-structure with a long or short range order which allows for molecular level tuning achieving superior thermo-mechanical characteristics. More particularly, the pads can be designed and fabricated so that there is both uniform and nonuniform spatial distribution of chemical and physical properties within the pads. In addition, these pads can be designed to tune the coefficient of friction by surface engineering, through the addition of solid lubricants, and creating low shear integral pads having multiple layers of polymeric material which form an interface parallel to the polishing surface. The pads can also have controlled porosity, embedded abrasive, novel grooves on the polishing surface, for slurry transport, which are produced in situ, and a transparent region for endpoint detection.
US08864858B1 Methods of fabricating a polycrystalline diamond compact including gaseous leaching of a polycrystalline diamond body
Embodiments of the invention relate to methods of fabricating polycrystalline diamond compacts (“PDCs”) and applications for such PDCs. In an embodiment, a method of fabricating a PDC includes providing a polycrystalline diamond (“PCD”) table in which a catalyst is disposed throughout, leaching the PCD table with a gaseous leaching agent to remove catalyst from the PCD table and bonding the at least partially leached PCD table to a substrate to form a PDC.
US08864857B1 Self regulating hydrogen generator
An apparatus for generating hydrogen gas from a replaceable aluminum pack comprising an aluminum and hydride mixture encased in a breathable membrane that is raised and lowered into a fluid contained within an enclosed tank wherein contact with the fluid releases hydrogen gas from the aluminum. A pressure transducer and microprocessor chip are provided for monitoring and regulating the rate of hydrogen production by engaging and disengaging a reversible motor that raises and lowers an inner tray on which the aluminum pack resides accordingly.
US08864852B2 Method for the fabrication of electrolyte cavities using surface micromachining
The present invention is directed to the fabrication of thin aluminum anode batteries using a highly reproducible process that enables high volume manufacturing of the galvanic cells. A method of fabricating a thin aluminum anode galvanic cell is provided, the method including, depositing a layer of catalytic metal on a surface of a first substrate, depositing and patterning a benzocyclobutene layer to form a reservoir having four sidewalls of benzocyclobutene on the surface of the catalytic layer, depositing a layer of aluminum on a surface of a second substrate and bonding the first substrate to the second substrate to form a galvanic cell bounded by the catalytic metal layer and the aluminum layer and separated by the reservoir walls of benzocyclobutene, the second substrate positioned in overlying relation to contact the four sidewalls of the reservoir with the aluminum layer facing the catalytic layer.
US08864850B2 Mixtures of reactive dyes and their use
Dye mixtures comprisingat least one dye of formula together with at least one dye from the group of formulae wherein the radicals have the definitions given in the claims, are suitable for dyeing or printing cellulose-containing fiber materials, while at the same time exhibiting good build-up behavior, and yield dyeings of deep shade having good fastness properties.
US08864849B1 Anionic azo dyestuffs for coloring keratin-containing fibers
The present specification provides for an agent for coloring keratinic fibers. The agent includes, a cosmetic carrier, a compound of formula (I), R1 and R2 independently of one another denote hydrogen, a C1-C6 alkyl group, a C2-C6 alkenyl group, a hydroxyl group, a halogen, a C1-C6 alkoxy group, an amino group, a nitro group, an acetyl amino group, or a sulfonamide group; or when in ortho-position to one another, form a 5- or 6-membered, saturated or unsaturated ring, which optionally include further heteroatoms.
US08864848B2 Zwitterionic azo dyestuffs for coloring keratin-including fibres
The invention relates to agents for coloring keratinic fibers, in particular human hair, including in a cosmetic carrier at least one compound of the formula (I). The structures the of the general formula (I) have a heterocycle A which bears a quaternary nitrogen atom and thus a positive charge. The invention furthermore relates to the use of these novel azo dyes in agents for coloring hair and to the dyes themselves.
US08864842B2 Self-cleaning stent
A stent is provided that is able to resist clogging from cumulative matter found within a fluid that passes therethrough. The stent includes a mass moveably disposed therein, wherein movement of the stent tends to dislodge any cumulative matter accumulated within the stent. As a result, the device is able to remain resident within the patient for an extended period of time before becoming clogged and needing to be replaced.
US08864841B2 Method for the displacement of the schneiderian membrane
Bioresorbable inflatable devices and tunnel incision tool and methods for treating and enlarging a tissue or an organ or a tube or a vessel or a cavity. The device is composed of a hollow expanding pouch made of a resorbable material or a perforated material that can be attached to a filling element. The pouch can be filled with a biocompatible materials, one or more times in few days interval, after the insertion of the device. While filling the pouch every few days the tissue expands and the filling material if it is bioactive start to function. The tunnel incision tool composed of a little blade that emerges from the surface of the tool in order to make shallow incisions in the surrounding tissue therefore enabling easy expansion of the tissue. This device and method can be used for example for: horizontal and vertical bone augmentation in the jaws and the tunnel incision tool is used to make shallow incisions in the periosteum when using the tunnel technique, sinus augmentation when the device is placed beneath the Schneiderian tissue, vessels widening if the pouch become a stent, fixating bone fractures etc.
US08864840B2 Intragastric implants with collapsible frames
Transoral obesity treatment devices and related methods for operation thereof are described which occupy space within a stomach and/or stimulate the stomach wall. The transoral obesity treatment devices and related methods are intended to assist a patient in maintaining a healthy body weight. Features of the devices include insertion transorally and without invasive surgery, without associated patient risks of invasive surgery, and without substantial patient discomfort. The life span of these devices may be material-dependent upon long-term survivability within an acidic stomach, but is intended to last one year or longer. The devices have the capacity to vary in size and are desirably self-actuating in that they change shape and/or volume using internal motors or actuators. The changing character of the devices helps prevent the person's stomach from compensating for the implant, such as sometimes happens with static intragastric devices.
US08864839B2 Bone implants and method of manufacture
An implant device for humans or mammals has a body structure having an exposed surface and one or more selected portions of the exposed surface having a bone formation enhancing 3-dimensional pattern. The exposed surface can be on exterior portions of the body structure or internal portions of the body structure or both. The one or more selected portions of the exposed portions having the bone formation enhancing 3-dimensional patterns are in the external exposed surfaces or in the internal exposed surfaces or both internal and external exposed surfaces.
US08864837B2 Screw-in element having changing thread profile and method for its production
The present invention relates to a screw-in element having a changing thread profile, in particular an artificial hip joint socket which may be screwed in, and a method for producing screw-in elements of this type. For the purpose of implementing a specific curve of the thread tooth height along the thread extension, it is suggested that the flank of the thread tooth pointing in the screw-in direction be implemented having a constant angle, and the other flank of the thread tooth be implemented having a changing angle. In addition, it is suggested that a type of staircase function made of ramps and steps be superimposed on the thread course to implement a clearance angle and an exposed position of the thread tooth in this way. The practical implementation of the method requires a CNC machine, preferably a CNC lathe, having a so-called B axis and a specific procedure in regard to the programming. The thread design according to the present invention results, in particular with a self-cutting design, in a reduction of the force required when screwing into tough material.
US08864836B2 ACL accommodating tibial design
Surgical methods and tibial implants (46) for accommodating the anterior cruciate ligament (ACL) during unicompartmental or bi-unicompartmental knee arthroplasty procedures.
US08864827B2 System and method for joint resurface repair
An implant comprising a first, second, and third segment wherein the second and third segments partially overlap the first segment and define a load bearing surface comprising an anterior-posterior (AP) curvature including at least two tangential curves of the portion of the articular surface of the femoral condyle, the tangential curves having different radii of curvature. A drill guide comprises a body portion including a first, second and third bushing spaced along the body portion to establish a first, second and third axes, respectively. Each axis may be substantially normal to the articular surface at three different points along a curvature of the articular surface comprising the two tangential curves. A measuring device comprises a housing defining a longitudinally passageway and an outrigger. A guide pin may be received in the longitudinal passageway and a measuring device determines how far the guide pin is in the passageway.
US08864825B2 Implant system
The present invention relates to an implant system comprising implantable material in at least partially uncured form, contained in a closed casing, under vacuum and sterilized, and a closed bag containing the casing. The system is characterized in that at least 5% of the surface of the casing comprises sheet-like material having a thickness of 0.05-5 mm and having an original form, the sheet-like material being selected from the group consisting of metallic materials, polymers, bioceramic materials and composites thereof, provided that the material, once deformed from its original form to a changed form, is capable of maintaining that changed form unless subjected to external forces.
US08864824B2 Method and apparatus for aligning a mask with the visual axis of an eye
A method is provided for increasing the depth of focus of an eye of a patient. A visual axis of the eye is aligned with an instrument axis of an ophthalmic instrument. The ophthalmic instrument has an aperture through which the patient may look along the instrument axis. A first reference target is imaged on the instrument axis at a first distance with respect to the eye. A second reference target is imaged on the instrument axis with the ophthalmic instrument at a second distance with respect to the eye. The second distance is greater than the first distance. Movement is provided such that the patient's eye is in a position where the images of the first and second reference targets appear to the patient's eye to be aligned. A mask comprising a pin-hole aperture having a mask axis is aligned with the instrument axis such that the mask axis and the instrument axis are substantially collinear. The mask is applied to the eye of the patient while the alignment of the mask axis and the instrument axis is maintained. Maintaining alignment of the mask axis and the instrument axis may be facilitated by capturing an image of the eye.
US08864823B2 Methods and apparatus for controlling the internal circumference of an anatomic orifice or lumen
An implantable device is provided for controlling shape and/or size of an anatomical structure or lumen. The implantable device has an adjustable member configured to adjust the dimensions of the implantable device. The implantable device is housed in a catheter and insertable from a minimally invasive surgical entry. An adjustment tool actuates the adjustable member and provide for adjustment before, during or after the anatomical structure or lumen resumes near normal to normal physiologic function.
US08864821B2 Methods and compositions for identifying subjects at risk of developing stent thrombosis
The invention provides methods and compositions for determining whether a subject containing a stent immobilized in a blood vessel has asymptomatic stent thrombosis or is at risk of developing clinically symptomatic stent thrombosis. In one approach, the method involves imaging a region of the blood vessel that contains the stent using a probe that contains a fluorochrome, for example, a near-infrared fluorochrome, and a targeting moiety that binds a molecular marker indicative of the presence of asymptomatic stent thrombosis or the development of symptomatic stent thrombosis. To the extent that the subject displays one or more such markers, the probe binds to the markers and increases the local concentration of the probe in the vicinity of the stent. The imaging method identifies those patients that display a higher density of such markers in the vicinity of the stent. As a result, those patients can be monitored for, and/or treated to prevent, symptomatic stent thrombosis.
US08864820B2 Selective coating of an implantable medical device
A coating and a method of coating an implantable medical device, such as a stent, is disclosed. The coating compensates for regions of higher stress and resulting strain due to the geometry of the device. Certain embodiments may include a nonuniform coating on the device in which a strain on the nonuniform coating is less than a strain on a uniform coating when the device is placed under an applied stress during use. Other embodiments may include a coating with a greater resistance to strain on higher strain regions of the device.
US08864819B2 Stented side branch graft
A stent graft (1) has a tubular body (3) defining a main lumen and a side tube (5) defining a side tube lumen and in fluid communication with the main lumen and defining a junction (13) between the tubular body and the side tube. The junction includes an acute angle of attachment (α). A first zig-zag stent (15) is wrapped around the tubular body such that a V portion of the first zig-zag stent is engaged about the acute angle of the junction and a second zig-zag stent (23) is wrapped around the side tube, such that a V portion of the second zig-zag stent is engaged about the acute angle of the junction, whereby the main lumen and the side tube are each kept open, independently, allowing fluid to flow freely therethrough.
US08864818B2 TiNxOy Modified surface for an implantable device and a method of producing the same
Implantable devices, such as stents, having a surface modified with TiNxOy or TiNxCy are disclosed.
US08864817B2 Endoprosthesis for vascular bifurcation
An apparatus for treating an area of bifurcation where a principal body conduit separates into at least two secondary conduits comprises a radially expandable first stent body. The first stent body has a substantially conical shape and a first end having a greater diameter than a second end when fully expanded. The first stent body is preferably shaped to be independent of any other stent bodies, and is free of any means for connecting to any other stent bodies when fully expanded.
US08864814B2 Method of delivering advanced endovascular graft and system
A flexible low profile delivery system for delivery of an expandable intracorporeal device, specifically, an endovascular graft, which has at least one belt circumferentially disposed about the device in a constraining configuration. The belt is released by a release member, such as a release wire, by retracting the wire from looped ends of the belt. Multiple belts can be used and can be released sequentially so as to control the order of release and placement of the endovascular graft. An outer protective sheath may be disposed about the endovascular graft while in a constrained state which must first be refracted or otherwise removed prior to release of the graft from a constrained state. The delivery system can be configured for delivery over a guiding device such as a guidewire. The delivery system can also be configured for delivery of bifurcated intracorporeal devices.
US08864813B2 Balloon/self-expanding stent graft
An intraluminal prosthesis for strengthening a lumen. The prosthesis may include a tubular graft (50) comprising a hollow flexible body (20). A self-expanding stent (19) may be coupled to the body (20) that provides enough outward radial force to expand the body. The prosthesis also includes a tubular stent (17). The tubular stent has a first diameter and a second expanded diameter. The tubular stent (17) is formable to the second diameter by application of an outwardly extending force from the interior of the tubular stent. The second diameter is at least equal to the interior diameter of the hollow flexible body (20).
US08864811B2 Bi-directional stent delivery system
A bi-directional stent delivery system includes an inner elongate shaft, a radially expandable prosthesis disposed over the inner elongate shaft, an outer elongate shaft, and a shuttle sheath disposed over the radially expandable prosthesis. The distal portion of the inner shaft is releasably coupled to the distal portion of the shuttle sheath, and the distal portion of the outer shaft is releasably coupled the proximal portion of the shuttle sheath. Distal advancement of the inner shaft advances the shuttle sheath distally when the outer shaft is uncoupled from the shuttle sheath, thereby allowing the prosthesis to radially expand from a proximal end to a distal end. Proximal retraction of the outer shaft retracts the shuttle sheath proximally when the inner shaft is uncoupled from the shuttle sheath, thereby allowing the prosthesis to radially expand from a distal end to a proximal end thereof.
US08864810B2 Device for implanting a vascular prosthesis
Implantation device for implanting a prosthesis (110) in a vessel (1), including a balloon (128) and a dilation catheter (120) for supplying fluid to the balloon (128), the dilation catheter (120) having a proximal end, a distal end (124) and a distal part designed to be introduced into the vessel (1), characterized in that the distal part includes a bend (123) and also an upstream portion (121) and a downstream portion (122) that are contiguous to the bend and that are arranged between the bend and, respectively, the proximal end and the distal end (124).
US08864807B2 Thermal regulation blanket and method of use thereof
A thermal regulation blanket includes a plurality of cells with a first reagent. A plurality of pouches with a second reagent are disposed within the plurality of cells. A plurality of dividers are disposed between each of the plurality of cells. A thermally conductive layer is disposed over the cells and the plurality of dividers. When the first reagent and the second reagent mix, a thermal reaction occurs which modifies a temperature of the thermally conductive layer. A method of providing thermal therapy to a patient includes positioning the patient on a thermal regulation blanket, an abdomen of the patient is engaged with at least one abdominal blanket of the thermal regulation blanket. At least one cell of the thermal regulation blanket is activated to begin providing thermal therapy to the patient. A temperature of the thermal regulation blanket is monitored with a temperature sensor. At least one additional cell is activated to adjust the temperature of the thermal regulation blanket.
US08864805B2 System for optical stimulation of target cells
Various systems and methods are implemented for controlling stimulus of a cell. One such method is implemented for optical stimulation of a cell expressing a NpHR ion pump. The method includes the step of providing a sequence of stimuli to the cell. Each stimulus increases the probability of depolarization events occurring in the cell. Light is provided to the cell to activate the expressed NpHR ion pump, thereby decreasing the probability of depolarization events occurring in the cell.
US08864802B2 Implant for bone fixation
An implant for use in orthopedic surgery for fixation of bone has a shaft region and a head region, both including a plurality of holes for receiving bone fasteners. The head region of the implant has a central screw hole and threaded surrounding screw holes surrounding the central screw hole in a defined configuration.