Document Document Title
US08786092B2 Semiconductor integrated circuit device
A semiconductor integrated circuit device includes: a rectangular shaped semiconductor substrate; a metal wiring layer formed on or over the semiconductor substrate; and a passivation layer covering the metal wiring layer. A corner non-wiring region where no portion of the metal wiring layer is formed is disposed in a corner of the semiconductor substrate. A slit is formed in a portion of the metal wiring layer which is close to the corner of the semiconductor substrate. The passivation layer includes a first passivation layer which is formed on the metal wiring layer and a second passivation layer which is formed on the first passivation layer. The first passivation layer is formed of a material that is softer than a material of the second passivation layer.
US08786091B2 Semiconductor apparatus having a high-aspect penetrating electrode and manufacturing method thereof
A semiconductor apparatus with a penetrating electrode having a high aspect ratio is manufactured with a low-temperature process. In one embodiment a first electrode 3 and a second electrode 6 of a semiconductor substrate 1 that are provided at the front and rear surface sides, respectively, are electrically connected by a conductive object 7 filled in a contact hole 4 and an extended portion 6a of the second electrode 6 extends to the contact hole 4. Even though the contact hole 4 has a high aspect ratio, film formation using the low-temperature process is enabled by using the conductive object 7, instead of forming the second electrode 6 on a bottom portion of the contact hole 4.
US08786089B2 Manufacturing method of semiconductor device, semiconductor device and electronic apparatus
A manufacturing method of a semiconductor device includes exposing a wiring layer which is formed of an alloy including two or more types of metals having different standard electrode potentials, on one surface side of a semiconductor substrate and performing a plasma process of allowing plasma generated by a mixture gas of a gas including nitrogen and an inert gas or plasma generated by a gas including nitrogen to irradiate a range which includes an exposed surface of the wiring layer.
US08786088B2 Semiconductor device including ultra low-K (ULK) metallization stacks with reduced chip-package interaction
In complex semiconductor devices, sophisticated ULK materials may be used in metal line layers in combination with a via layer of enhanced mechanical stability by increasing the amount of dielectric material of superior mechanical strength. Due to the superior mechanical stability of the via layers, reflow processes for directly connecting the semiconductor die and a package substrate may be performed on the basis of a lead-free material system without unduly increasing yield losses.
US08786087B2 Semiconductor device having damascene interconnection structure that prevents void formation between interconnections having transparent dielectric substrate
A semiconductor device is made up of a first insulating layer having a through hole; a first interconnection which includes a first conductive layer, a first barrier layer, and a first main interconnection, and a second interconnection connected to one of the first conductive layer and the first barrier layer. Accordingly, the semiconductor device can avoid a problem where the material of the first main interconnection transfers from a portion connected to the second interconnection due to electromigration to form a void, with the result that the first interconnection is disconnected from the second interconnection.
US08786086B2 Semiconductor device including wiring having main portion and extended portion
A semiconductor device includes a semiconductor substrate; an insulating film formed over the semiconductor substrate, there being formed in the insulating film a trench that in a sectional view has a stepped shape; and a wiring formed in the trench, wherein the wiring includes, a main portion with a first thickness; and an extended portion with a second thickness that is thinner than the first thickness and that extends outward from a side of the main portion.
US08786084B2 Semiconductor package and method of forming
A semiconductor package includes a semiconductor die attached to a support having electrically conductive paths, the semiconductor die having a bond-pad electrically connected to the electrically a conductive path on the support by a bond-wire of a first metallic composition, the bond-wire and the bond-pad being coated with a protection layer of a second metallic composition.
US08786082B2 Semiconductor structure having no adjacent bumps between two adjacent pads
A semiconductor structure is provided. The semiconductor structure includes a substrate, at least two pads, a passivation layer, at least two under bump metallization (UBM) layers and at least two bumps. The pads are disposed adjacent to each other on the substrate along the first direction. The passivation layer covers the substrate and the peripheral upper surface of each pad to define an opening. Each of the openings defines an opening projection along the second direction. The opening projections are disposed adjacent to each other but not overlapping with each other. Furthermore, the first direction is perpendicular to the second direction. The UBM layers are disposed on the corresponding openings, and the bumps are respectively disposed on the corresponding UBM layers. With the above arrangements, the width of each bump of the semiconductor structure of the present invention could be widened without being limited by the bump pitch.
US08786081B2 Method and device for circuit routing by way of under-bump metallization
A semiconductor device includes a substrate that contains a plurality of electronic components/elements. The semiconductor device includes an interconnect structure disposed over the substrate, the interconnect structure containing a plurality of interconnect layers. The semiconductor device includes a passivation layer disposed over the interconnect structure. The semiconductor device includes an Under-Bump Metallization (UBM) layer disposed over the passivation layer, the UBM layer containing a UBM pad and a plurality of UBM devices, the UBM devices including at least one of: a UBM trace that is electrically coupled to one of the electronic components through the interconnect structure, and a dummy UBM device. The semiconductor device includes a solder bump disposed on, and electrically coupled to, the UBM pad.
US08786079B2 Antenna switch modules and methods of making the same
Antenna switch modules and methods of making the same are provided. In certain implementations, an antenna switch module includes a package substrate, an integrated filter, and a silicon on insulator (SOI) die attached to the package substrate. The SOI die includes a capacitor configured to operate in the integrated filter and a multi throw switch for selecting amongst the RF signal paths. In some implementations, a surface mount inductor is attached to the package substrate adjacent the SOI die and is configured to operate in the integrated filter with the capacitor. In certain implementations, the inductor is formed from a conductive layer of the package substrate disposed beneath a layer of the package substrate used to attach the SOI die.
US08786078B1 Vehicles, power electronics modules and cooling apparatuses with single-phase and two-phase surface enhancement features
Jet-impingement, two-phase cooling apparatuses and power electronics modules having a target surface with single- and two-phase surface enhancement features are disclosed. In one embodiment, a cooling apparatus includes a jet plate surface and a target layer. The jet plate surface includes a jet orifice having a jet orifice geometry, wherein the jet orifice is configured to generate an impingement jet of a coolant fluid. The target layer has a target surface, single-phase surface enhancement features, and two-phase surface enhancement features. The target surface is configured to receive the impingement jet, and the single-phase surface enhancement features and the two-phase enhancement features are arranged on the target surface according to the jet orifice geometry. The single-phase surface enhancement features are positioned on the target surface at regions associated with high fluid velocity, and the two-phase surface enhancement features are positioned on the target surface at regions associated with low fluid velocity.
US08786077B2 Semiconductor device having a first substrate containing circuit element connected to radiation plate on a cover plate with metal vias
Certain embodiments provide a semiconductor device including a first substrate, a circuit element, a second substrate, a metal layer, and a radiation plate. The circuit element is formed on a front surface of the first substrate and has an electrode. The second substrate has a first face, and is laminated on the first substrate so that the first face of the second substrate faces a front surface of the first substrate. The second substrate has a via hole arranged on the electrode. The metal layer is formed inside of the via hole. The radiation plate is formed on a second face of the second substrate, and is connected to the metal layer.
US08786074B2 Packaging device for matrix-arrayed semiconductor light-emitting elements of high power and high directivity
A packaging device for matrix-arrayed semiconductor light-emitting elements of high power and high directivity comprises a metal base, an array chip and a plurality of metal wires. The metal base is of highly heat conductive copper or aluminum, and a first electrode area and at least one second electrode area which are electrically isolated are disposed on the metal base. The array chip is disposed on the first electrode area, on which multiple matrix-arranged semiconductor light-emitting elements and at least one wire bond pad adjacent to the light-emitting elements are disposed. The light-emitting element is a VCSEL element, an HCSEL element or an RCLED element. The metal wires are connected between the wire bond pad and the second electrode area to transmit power signals. Between the bottom surface and the first electrode area is disposed a conductive adhesive to bond and facilitate electrical connection between the two.
US08786073B2 Packaging device for matrix-arrayed semiconductor light-emitting elements of high power and high directivity
A packaging device for matrix-arrayed semiconductor light-emitting elements of high power and high directivity comprises a metal base, an array chip and a plurality of metal wires. The metal base is of highly heat conductive copper or aluminum, and a first electrode area and at least one second electrode area which are electrically isolated are disposed on the metal base. The array chip is disposed on the first electrode area, on which multiple matrix-arranged semiconductor light-emitting elements and at least one wire bond pad adjacent to the light-emitting elements are disposed. The light-emitting element is a VCSEL element, an HCSEL element or an RCLED element. The metal wires are connected between the wire bond pad and the second electrode area to transmit power signals. Between the bottom surface and the first electrode area is disposed a conductive adhesive to bond and facilitate electrical connection between the two.
US08786070B2 Microelectronic package with stacked microelectronic elements and method for manufacture thereof
A microelectronic package may include a stacked microelectronic unit including at least first and second vertically stacked microelectronic elements each having a front face facing a top surface of the package. The front face of the first element may be adjacent the top surface, and the first element may overlie the front face of the second element such that at least a portion of the front face of the second element having an element contact thereon extends beyond an edge of the first element. A conductive structure may electrically connect a first terminal at the top surface to an element contact at the front face of the second element, and include a continuous monolithic metal feature extending along the top surface and through at least a portion of an encapsulant, which is between the top surface and the front face of the second element, towards the element contact.
US08786068B1 Packaging of electronic circuitry
A circuit package includes: electronic circuitry, electrically conductive material forming multiple leads, and multiple connections between the electronic circuitry and the multiple leads. A portion of the electrically conductive material associated with the multiple leads (e.g., low impedance leads supporting high current throughput) is removed to accommodate placement of the electronic circuitry. Each of the multiple leads can support high current. The multiple connections between the multiple leads provide connectivity between circuit nodes on the electronic circuitry and pads disposed on a planar surface of the electronic circuit package.
US08786065B2 Substrate, light emitting device and method for manufacturing substrate
A substrate includes a first lead frame, a second lead frame, and a resin layer. The first lead frame includes a heat sink and a plurality of electrodes for external connection. The second lead frame is laminated on the first lead frame and includes a plurality of wirings for mounting light emitting elements. The resin layer is filled between the first lead frame and the second lead frame. The plurality of wirings are arranged above the heat sink. The plurality of electrodes and part of the plurality of wirings are joined with each other.
US08786064B2 Semiconductor package and method for manufacturing the same and semiconductor package module having the same
Disclosed herein is a semiconductor chip, including: a first substrate having a concave formed on one surface thereof and an opening formed on a bottom surface of the concave; a second substrate contacting the other surface of the first substrate; and a semiconductor chip mounted in the concave.
US08786063B2 Integrated circuit packaging system with leads and transposer and method of manufacture thereof
A method of manufacture of an integrated circuit packaging system includes: conductively bonding a first surface of a transposer to an inner end of a lead separate from the transposer; conductively bonding a die to the first surface of the transposer; and encapsulating the inner end with a mold compound having a bottom mold surface that is exposed and is coplanar with a surface of the transposer opposite the first surface.
US08786062B2 Semiconductor package and process for fabricating same
A package carrier includes: (a) a dielectric layer defining a plurality of openings; (b) patterned electrically conductive layer, embedded in the dielectric layer and disposed adjacent to a first surface of the dielectric layer; a plurality of electrically conductive posts, disposed in respective ones of the openings, wherein the openings extend between a second surface of the dielectric layer to the patterned electrically conductive layer, the electrically conductive posts a connected to the patterned electrically conductive layer, and an end of each of the electrically conductive posts has a curved profile and is faced away from the patterned electrically conductive layer; and (d) a patterned solder resist layer, disposed adjacent to the first surface of the dielectric layer and exposing portions of the patterned electrically conductive layer corresponding to contact pads. A semiconductor package includes the package carrier, a chip, and an encapsulant covering the chip and the package carrier.
US08786057B2 Integrated circuit on corrugated substrate
By forming MOSFETs on a substrate having pre-existing ridges of semiconductor material (i.e., a “corrugated substrate”), the resolution limitations associated with conventional semiconductor manufacturing processes can be overcome, and high-performance, low-power transistors can be reliably and repeatably produced. Forming a corrugated substrate prior to actual device formation allows the ridges on the corrugated substrate to be created using high precision techniques that are not ordinarily suitable for device production. MOSFETs that subsequently incorporate the high-precision ridges into their channel regions will typically exhibit much more precise and less variable performance than similar MOSFETs formed using optical lithography-based techniques that cannot provide the same degree of patterning accuracy. Additional performance enhancement techniques such as pulse-shaped doping and “wrapped” gates can be used in conjunction with the segmented channel regions to further enhance device performance.
US08786056B2 Semiconductor light emitting elements comprising a plating substrate with a projecting tab, or comprising an exposed seed layer
A method of forming a semiconductor light emitting element. The method can include forming a seed layer on a semiconductor layer assembly including at least one nitride semiconductor layer. An insulating mask can be formed on the seed layer. The insulating mask can include a plurality of element areas separated by cross spaces. Each element area of the plurality of element areas can be connected to at least one of the other element areas of the plurality of element areas. The seed layer can be plated such that a plating substrate is formed in each of the plurality of element areas.
US08786055B2 Solid-state imaging device, method for manufacturing solid-state imaging device, method for manufacturing solid-state imaging element, and semiconductor device
A solid-state imaging device includes a semiconductor substrate configured to include a solid-state imaging element that is provided with a photoelectric conversion region, and a scribe line region that is provided along a periphery of the solid-state imaging element, a wiring layer that is formed to be layered on the semiconductor substrate, a support substrate that is formed to be layered on the wiring layer, and a groove that is provided between a blade region in the scribe line region and the solid-state imaging element, in the semiconductor substrate and penetrates through the semiconductor substrate.
US08786052B2 Nitride semiconductor crystal producing method, nitride semiconductor epitaxial wafer, and nitride semiconductor freestanding substrate
A nitride semiconductor crystal producing method, a nitride semiconductor epitaxial wafer, and a nitride semiconductor freestanding substrate, by which it is possible to suppress the occurrence of cracking in the nitride semiconductor crystal and to ensure the enhancement of the yield of the nitride semiconductor crystal. The nitride semiconductor crystal producing method includes growing a nitride semiconductor crystal over a seed crystal substrate, while applying an etching action to an outer end of the seed crystal substrate during the growing of the nitride semiconductor crystal.
US08786043B2 High performance GeSi avalanche photodiode operating beyond Ge bandgap limits
Avalanche photodiodes (APDs) having at least one top stressor layer disposed on a germanium (Ge)-containing absorption layer are described herein. The top stressor layer can increase the tensile strain of the Ge-containing absorption layer, thus extending the absorption of APDs to longer wavelengths beyond 1550 nm. In one embodiment, the top stressor layer has a four-layer structure, including an amorphous silicon (Si) layer disposed on the Ge-containing absorption layer; a first silicon dioxide (SiO2) layer disposed on the amorphous Si layer, a silicon nitride (SiN) layer disposed on the first SiO2 layer, and a second SiO2 layer disposed on the SiN layer. The Ge-containing absorption layer can be further doped by p-type dopants. The doping concentration of p-type dopants is controlled such that a graded doping profile is formed within the Ge-containing absorption layer to decrease the dark currents in APDs.
US08786042B2 Photodetector with a plasmonic structure
This photodetector capable of detecting electromagnetic radiation comprises: a doped semiconductor absorption layer for said radiation, capable of converting said radiation into charge carriers; a reflective layer that reflects the incident radiation that is not absorbed by semiconductor layer towards the latter, located underneath semiconductor layer; and a metallic structure placed on semiconductor layer that forms, with semiconductor layer, a surface Plasmon resonator so as to concentrate the incident electromagnetic radiation on metallic structure in the field concentration zones of semiconductor layer. Semiconductor zones for collecting charge carriers that are oppositely doped to the doping of semiconductor layer are formed in said semiconductor layer and have a topology that complements that of the field concentration zones.
US08786025B2 Semiconductor device and method for forming same
A system and method for forming a resistor system is provided. An embodiment comprises a resistor formed in a U-shape. The resistor may comprise multiple layers of conductive materials, with a dielectric layer filling the remainder of the U-shape. The resistor may be integrated with a dual metal gate manufacturing process or may be integrated with multiple types of resistors.
US08786020B2 Method of fabricating a semiconductor device including a gate having a plurality of fingers extended over a plurality of isolation regions
Embodiments of the present invention describe a semiconductor device implementing the reduced-surface-field (RESURF) effect. The semiconductor device comprises a source/drain region having a plurality of isolation regions interleaved with source/drain extension regions. A gate electrode is formed on the semiconductor device, where the gate electrode includes gate finger elements formed over the isolation regions to induce capacitive coupling. The gate finger elements enhance the depletion of the source/drain extension regions, thus inducing a higher breakdown voltage.
US08786013B2 Trench transistor
A method of forming a device is disclosed. A substrate defined with a device region is provided. A buried doped region is formed in the substrate in the device region. A gate is formed in a trench in the substrate in the device region. A channel of the device is disposed on a sidewall of the trench. The buried doped region is disposed below the gate. A distance from the buried doped region to the channel is a drift length LD of the device. A surface doped region is formed adjacent to the gate.
US08786012B2 Power semiconductor device and a method for forming a semiconductor device
A power semiconductor device has a semiconductor body which includes an active area and a peripheral area which both define a horizontal main surface of the semiconductor body. The semiconductor body further includes an n-type semiconductor layer, a pn junction and at least one trench. The n-type semiconductor layer is embedded in the semiconductor body and extends to the main surface in the peripheral area. The pn junction is arranged between the n-type semiconductor layer and the main surface in the active area. The at least one trench extends in the peripheral area from the main surface into the n-type semiconductor layer and includes a dielectric layer with fixed negative charges. In the vertical direction, the dielectric layer is arranged both below and above the pn junction. The dielectric layer with fixed negative charges typically has a negative net charge. Further, a method for forming a semiconductor device is provided.
US08786009B2 Substrate structures including buried wiring, semiconductor devices including substrate structures, and method of fabricating the same
A semiconductor device includes a substrate structure including a first substrate and a second substrate, and a buried wiring interposed between the first substrate and the second structure, where the buried wiring is in direct contact with the second substrate. The semiconductor device further includes a vertical transistor located in the second substrate of the substrate structure. The vertical transistor includes a gate electrode and a semiconductor pillar, and the buried wiring is one of source electrode or a drain electrode of the vertical transistor.
US08786006B2 Flash memory device having a graded composition, high dielectric constant gate insulator
A graded composition, high dielectric constant gate insulator is formed between a substrate and floating gate in a flash memory cell transistor. The gate insulator comprises amorphous germanium or a graded composition of germanium carbide and silicon carbide. If the composition of the gate insulator is closer to silicon carbide near the substrate, the electron barrier for hot electron injection will be lower. If the gate insulator is closer to the silicon carbide near the floating gate, the tunnel barrier can be lower at the floating gate.
US08786003B2 Nonvolatile semiconductor memory device and method for manufacturing same
According to one embodiment, a nonvolatile semiconductor memory device includes: a substrate; a memory unit provided on the substrate; and a non-memory unit provided on the substrate. The memory unit includes: a first stacked body including a plurality of first electrode films and a first inter-electrode insulating film, the plurality of first electrode films being stacked along a first axis perpendicular to the major surface, the first inter-electrode insulating film being provided between two of the first electrode films mutually adjacent along the first axis; a first semiconductor layer opposing side surfaces of the first electrode films; a first memory film provided between the first semiconductor layer and the first electrode films; and a first conductive film provided on the first stacked body apart from the first stacked body. The non-memory unit includes a resistance element unit of the same layer as the conductive film.
US08786000B2 Semiconductor device suppressing peeling of lower electrode of capacitor
A method of manufacturing a semiconductor device includes: forming a core insulating film that includes first openings, on a semiconductor substrate; forming cylindrical lower electrodes that cover sides of the first openings with a conductive film; forming a support film that covers at least an upper surface of the core insulating film between the lower electrodes; forming a mask film in which an outside of a region where at least the lower electrodes are formed is removed, by using the support film; and performing isotropic etching on the core insulating film so as to leave the core insulating film at a part of an area between the lower electrodes, after the mask film is formed.
US08785995B2 Ferroelectric semiconductor transistor devices having gate modulated conductive layer
Ferroelectric semiconductor switching devices are provided, including field effect transistor (FET) devices having gate stack structures formed with a ferroelectric layer disposed between a gate contact and a thin conductive layer (“quantum conductive layer”). The gate contact and ferroelectric layer serve to modulate an effective work function of the thin conductive layer. The thin conductive layer with the modulated work function is coupled to a semiconductor channel layer to modulate current flow through the semiconductor and achieve a steep sub-threshold slope.
US08785992B2 Light-guiding structure, image sensor including the light-guiding structure, and processor-based system including the image sensor
An example embodiment relates to a light-guiding structure. The light-guiding structure may include a bottom surface and a sidewall defined by a first, a second, and a third insulating layer disposed on a semiconductor substrate. The bottom surface may be parallel to a main surface of the semiconductor substrate and may be disposed in the first insulating layer. The sidewall may penetrate the second and third insulating layers to extend to the first insulating layer, and the sidewall may be tapered with respect to the main surface of semiconductor substrate. The light-guiding structure may be included in a image sensor. The image sensor may be included in a processor-based system.
US08785991B2 Solid state imaging device, method for producing the same, and electronic apparatus
A solid state imaging device includes a photoelectric conversion portion in which the shape of potential is provided such that charge is mainly accumulated in a vertical direction.
US08785986B1 BCMD image sensor with junction gate for back side or front side illumination
The invention describes the solid-state image sensor array and in particular describes in detail the junction gate BCMD pixel sensor array that can be used in the back side illuminated mode as well as in the front side illuminated mode. The pixels generally do not need addressing transistors and the reset is accomplished in a vertical direction to the junction gate, so no additional reset transistor is needed for this purpose. As a result of this innovation the pixel maintains large charge storage capacity when its size is reduced, has low noise due to the nondestructive charge readout, and no RTS noise. The pixel interface generated dark current is also drained to the gate, so the image sensor array operates with very low dark current noise even at high temperatures. The junction gate also serves as a drain for the overflow charge.
US08785985B2 Sensor for detecting a component of a gas mixture
A sensor for detecting a first component in a gas mixture is disclosed having a gas-sensitive electrode and a catalyst which is arranged on and/or spaced apart from the electrode in a porous carrier ceramic. The catalyst has the effect that a second component in the gas mixture is chemically altered such that the component contributes to no substantial change in the potential of the electrode.
US08785984B2 Method for making multi-step photodiode junction structure for backside illuminated sensor
A method of making a backside illuminated sensor is provided. A substrate is provided and a high energy ion implantation is performed over the substrate to implant a first doped region. A layer is formed over the substrate and a self-align high energy ion implantation is performed over the substrate to implant a second doped region over the first doped region. The combined thickness of the first and second doped region is greater than 50 percent of thickness of the substrate and the distance between back surface of the substrate and the first and second doped regions is less than 50 percent of thickness of the substrate. In this way, an enlarged light sensing region is formed through which electrons generated from back surface of the surface may easily reach the pixel.
US08785982B2 Pixel for depth sensor and image sensor including the pixel
A unit pixel of a depth sensor including a light-intensity output circuit configured to output a pixel signal according to a control signal, the pixel signal corresponding to a first electric charge and a second electric charge, a first light-intensity extraction circuit configured to generate the first electric charge and transmit the first electric charge to the light-intensity output circuit, the first electric charge varying according to an amount of light reflected from a target object and a second light-intensity extraction circuit configured to generate the second electric charge and transmit the second electric charge to the light-intensity output circuit, the second electric charge varying according to the amount of reflected light. The light-intensity output circuit includes a first floating diffusion node. Accordingly, it is possible to minimize waste of a space, thereby manufacturing a small-sized pixel.
US08785981B1 Non-replacement gate nanomesh field effect transistor with pad regions
A gate-first processing scheme for forming a nanomesh field effect transistor is provided. An alternating stack of two different semiconductor materials is patterned to include two pad regions and nanowire regions. A semiconductor material is laterally etched selective to another semiconductor material to form a nanomesh including suspended semiconductor nanowires. A stack of a gate dielectric, a gate electrode, and a gate cap dielectric is formed over the nanomesh. A dielectric spacer is formed around the gate electrode. An isotropic etch is employed to remove dielectric materials that are formed in lateral recesses of the patterned alternating stack. A selective epitaxy process can be employed to form a source region and a drain region.
US08785978B2 Integrated circuit including cross-coupled transistors having gate electrodes formed within gate level feature layout channels with electrical connection of cross-coupled transistors through same interconnect layer
A semiconductor device includes a cross-coupled transistor configuration formed by first and second PMOS transistors defined over first and second p-type diffusion regions, and by first and second NMOS transistors defined over first and second n-type diffusion regions, with each diffusion region electrically connected to a common node. Gate electrodes of the PMOS and NMOS transistors are formed by conductive features which extend in only a first parallel direction. At least a portion of each of the first and second p-type diffusion regions are formed over a first common line of extent that extends perpendicular to the first parallel direction. The first and second n-type diffusion regions are formed in a spaced apart manner relative to the first parallel direction, such that no single line of extent that extends across the substrate perpendicular to the first parallel direction intersects both the first and second n-type diffusion regions.
US08785976B2 Polarization super-junction low-loss gallium nitride semiconductor device
A low-loss GaN-based semiconductor device is provided.The semiconductor device has the InzGa1-zN layer (where 0≦z<1), the AlxGa1-xN layer (where 0
US08785975B2 GAN vertical superjunction device structures and fabrication methods
A semiconductor device includes a III-nitride substrate of a first conductivity type, a first III-nitride epitaxial layer of the first conductivity type coupled to the III-nitride substrate, and a first III-nitride epitaxial structure coupled to a first portion of a surface of the first III-nitride epitaxial layer. The first III-nitride epitaxial structure has a sidewall. The semiconductor device further includes a second III-nitride epitaxial structure of the first conductivity type coupled to the first III-nitride epitaxial structure, a second III-nitride epitaxial layer of the first conductivity type coupled to the sidewall of the second III-nitride epitaxial layer and a second portion of the surface of the first III-nitride epitaxial layer, and a third III-nitride epitaxial layer of a second conductivity type coupled to the second III-nitride epitaxial layer. The semiconductor device also includes one or more dielectric structures coupled to a surface of the third III-nitride epitaxial layer.
US08785973B2 Ultra high voltage GaN ESD protection device
In an ultra high voltage lateral GaN structure having a 2DEG region extending between two terminals, an isolation region is provided between the two terminals to provide for reversible snapback.
US08785971B2 Transient voltage suppressor without leakage current
A transient voltage suppressor without leakage current is disclosed, which comprises a P-substrate. There is an N-type epitaxial layer formed on the P-substrate, and a first N-heavily doped area, a first P-heavily doped area, an electrostatic discharge (ESD) device and at least one deep isolation trench are formed in the N-epitaxial layer. A first N-buried area is formed in the bottom of the N-epitaxial layer to neighbor the P-substrate and located below the first N-heavily doped area and the first P-heavily doped area. The ESD device is coupled to the first N-heavily doped area. The deep isolation trench is not only adjacent to the first N-heavily doped area, but has a depth greater than a depth of the first N-buried area, thereby separating the first N-buried area and the ESD device.
US08785967B2 Local crystallization by heat treatment
Disclosed is a crystallization apparatus capable of locally crystallizing amorphous silicon. The crystallization apparatus includes a heat emission part, a support part and a roller. The heat emission part emits heat upon receiving a heat emission source. The support part supports the heat emission part and provides the heat emission source to the heat emission part. The roller receives the heat emission part and has at least one opening to provide heat to a target (e.g., amorphous silicon). Local crystallization is performed without causing damage to a substrate.
US08785964B2 Panel light comprising a light-emitting device
In a sealing method of a top-emission organic light emitting element, in the case of using a method of filling with a sealing agent between a substrate mounted with pixels and an opposed substrate, the organic light-emitting element is degraded by ultraviolet rays when irradiation of the ultraviolet rays is performed toward the pixels in order to achieve ultraviolet curing of the sealing agent filling on the pixels. It is an object of the present invention to propose a method for avoiding this phenomenon to provide an organic light-emitting device with superior stability. In order for a sealing agent 13 filling on a pixel portion 14 to have a larger absorbance to ultraviolet rays, an ultraviolet-absorbent material is dispersed in a sealing agent to make an adjustment so that the absorbance of ultraviolet absorption wavelength of 400 nm or less becomes 1 or more.
US08785954B2 Organic light-emitting device
An organic light-emitting device includes a substrate, an anode including Ag on the substrate, a transparent inorganic thin-film layer on the anode, the transparent inorganic thin-film layer being in contact with the anode and having non-conductive characteristics; and an emitting layer and a cathode disposed sequentially on the inorganic thin-film layer.
US08785952B2 Light emitting device and light emitting device package including the same
A light emitting device is disclosed. The light emitting device includes a first electrode and a second electrode, which have different areas, thereby achieving enhanced bonding reliability.
US08785950B2 Chip with semiconductor electricity conversion structure
A semiconductor electricity conversion structure is provided. The semiconductor electricity conversion structure includes: a substrate; and at least one semiconductor electricity conversion structure formed on the substrate, the at least one semiconductor electricity conversion structure including: at least one semiconductor electricity-to-light conversion unit for converting an input electric energy into a light energy, and at least one semiconductor light-to-electricity conversion unit for converting the light energy back into an output electric energy, in which a number of the semiconductor electricity-to-light conversion unit is in proportion to a number of the semiconductor light-to-electricity conversion unit to realize an electricity conversion, and an emitting spectrum of the semiconductor electricity-to-light conversion unit and an absorption spectrum of the semiconductor light-to-electricity conversion unit are matched with each other.
US08785948B2 Light-emitting device and electronic apparatus
A light-emitting device includes a drive transistor that controls a current to be supplied to a light-emitting element from a power supply line, an element continuity portion that electrically connects the drive transistor with the light-emitting element, an initializing transistor that is turned ON to diode-connect the drive transistor, and a connecting portion that electrically connects the drive transistor with the initializing transistor. The power supply line includes a first portion extending in a predetermined direction. The element continuity portion and the connecting portion are formed from the same layer as that of the power supply line and are located on one side along the width of the first portion across the drive transistor.
US08785943B2 Nitride semiconductor device, nitride semiconductor wafer, and method for manufacturing nitride semiconductor layer
According to one embodiment, a nitride semiconductor device includes a foundation layer, a first stacked intermediate layer, and a functional layer. The foundation layer includes an AlN buffer layer formed on a substrate. The first stacked intermediate layer is provided on the foundation layer. The first stacked intermediate layer includes a first AlN intermediate layer provided on the foundation layer, a first AlGaN intermediate layer provided on the first AlN intermediate layer, and a first GaN intermediate layer provided on the first AlGaN intermediate layer. The functional layer is provided on the first stacked intermediate layer. The first AlGaN intermediate layer includes a first step layer in contact with the first AlN intermediate layer. An Al composition ratio in the first step layer decreases stepwise in a stacking direction from the first AlN intermediate layer toward the first step layer.
US08785937B2 Organic light-emitting display apparatus and method of manufacturing the same
An organic light-emitting display apparatus that includes a thin film transistor comprising an active layer, a gate electrode, and source and drain electrodes electrically connected to the active layer; a pixel electrode formed on the same layer as the gate electrode; a light-emitting layer formed on the pixel electrode; a passivation layer formed on upper surfaces of the source and drain electrodes and upper surfaces of wirings formed on the same layer as the source and drain electrodes; an organic insulating layer that covers the thin film transistor, comprises an opening that exposes an upper surface of the pixel electrode, and directly contacts the passivation layer; and a facing electrode that is formed on the light-emitting layer, and is formed to directly contact the organic insulating layer to face the pixel electrode.
US08785933B2 Semiconductor device
A semiconductor device of the present invention includes a gate electrode which includes a pair of first protrusions and a second protrusion provided between the pair of first protrusions; a gate insulating film covering the gate electrode; a semiconductor film which is in contact with the gate insulating film and overlaps with the pair of first protrusions and the second protrusion; and a pair of electrodes which is in contact with the semiconductor film and overlaps with the pair of first protrusions. The side edges of the semiconductor film are on the outer sides than the top surfaces of the pair of first protrusions in the direction of the channel width of the semiconductor film. The side edges of the pair of electrodes are on the outer sides than the top surfaces of the pair of first protrusions in the direction of the channel width of the semiconductor film.
US08785932B2 IR sensing transistor and manufacturing method of display device including the same
An IR sensing transistor according to an exemplary embodiment of the present invention includes: a light blocking layer formed on a substrate; a gate insulating layer formed on the light blocking layer; a semiconductor formed on the gate insulating layer; a pair of ohmic contact members formed on the semiconductor; a source electrode and a drain electrode formed on respective ones of the ohmic contact members; a passivation layer formed on the source electrode and the drain electrode; and a gate electrode formed on the passivation layer, wherein substantially all of the gate insulating layer lies on the light blocking layer.
US08785922B2 Thin film transistor, organic luminescence display including the same, and method of manufacturing the organic luminescence display
A thin film transistor (TFT) including a substrate; a gate electrode formed over the substrate, an active layer insulated from the gate electrode by using a gate insulation film; an etch stop layer which is formed over the active layer and includes first and second holes for exposing the active layer; a first electrode; and a second electrode including a first part and a second part. The first part is formed over the etch stop layer, and the second part is received in the second hole, contacts the active layer directly, and connects the first part to the active layer. At least one portion of the first part of the second electrode overlaps with the gate electrode. The second part of the second electrode does not overlap with and is separated from the gate electrode.
US08785921B2 Device comprising positive hole injection transport layer, method for producing the same and ink for forming positive hole injection transport layer
A device capable of having an easy production process and achieving a long lifetime. The device has a substrate, two or more electrodes facing each other disposed on the substrate and a positive hole injection transport layer disposed between two electrodes among the two or more electrodes. The positive hole injection transport layer has a transition metal-containing nanoparticle containing at least a transition metal compound including a transition metal oxide, a transition metal and a protecting agent, or at least the transition metal compound including the transition metal oxide, and the protecting agent.
US08785920B2 Semiconductor thin film, semiconductor thin film manufacturing method and semiconductor element
An amorphous oxide thin film containing amorphous oxide is exposed to an oxygen plasma generated by exciting an oxygen-containing gas in high frequency. The oxygen plasma is preferably generated under the condition that applied frequency is 1 kHz or more and 300 MHz or less and pressure is 5 Pa or more. The amorphous oxide thin film is preferably exposed by a sputtering method, ion-plating method, vacuum deposition method, sol-gel method or fine particle application method.
US08785914B2 Piezoelectric nanowire structure and electronic device including the same
A piezoelectric nanowire structure includes a base substrate, a plurality of piezoelectric nanowires disposed on the base substrate, and a piezoelectric organic material layer disposed on the base substrate and covering the plurality of piezoelectric nanowires.
US08785913B2 Buffer bilayers for electronic devices
The present invention relates to buffer bilayers, and their use in electronic devices. The bilayer has a first layer including (i) at least one electrically conductive polymer doped with at least one non-fluorinated polymeric acid and (ii) at least one highly-fluorinated acid polymer. The bilayer has a second layer which is a reacted layer from a metal which can be one or more transition metals, Group 13 metals, Group 14 metals, or lanthanide metals.
US08785909B2 Non-planar semiconductor device having channel region with low band-gap cladding layer
Non-planar semiconductor devices having channel regions with low band-gap cladding layers are described. For example, a semiconductor device includes a vertical arrangement of a plurality of nanowires disposed above a substrate. Each nanowire includes an inner region having a first band gap and an outer cladding layer surrounding the inner region. The cladding layer has a second, lower band gap. A gate stack is disposed on and completely surrounds the channel region of each of the nanowires. The gate stack includes a gate dielectric layer disposed on and surrounding the cladding layer and a gate electrode disposed on the gate dielectric layer. Source and drain regions are disposed on either side of the channel regions of the nanowires.
US08785903B2 Memory cell array and variable resistive memory device including the same
A memory cell array and a resistive variable memory device including the memory cell array are provided. The memory cell array includes a memory group. The memory cell array includes a pair of word lines, an inter-pattern insulating layer interposed between the pair of word lines, and a plurality of active pillars, each having one side contacted with the inter-pattern insulating layer and other sides surrounded by the word line.
US08785901B2 Semiconductor devices having metal oxide patterns
Methods of fabricating semiconductor devices are provided including forming a dielectric interlayer on a substrate, the dielectric interlayer defining an opening therein. A metal pattern is formed in the opening. An oxidization process is performed on the metal pattern to form a conductive metal oxide pattern, and the conductive metal oxide pattern is planarized. Related semiconductor devices are also provided.
US08785900B2 Resistive memory and methods of processing resistive memory
Resistive memory and methods of processing resistive memory are described herein. One or more method embodiments of processing resistive memory include forming a resistive memory cell material on an electrode having an access device contact, and forming a heater electrode on the resistive memory cell material after forming the resistive memory cell material on the electrode such that the heater electrode is self-aligned to the resistive memory cell material.
US08785898B2 Device and method for detecting liquid level of molten silicon using laser reflected from curved mirror
A laser liquid level detection device is provided with linear optical magnification of a curved minor. The device includes a laser device, a CCD detecting device having a curved mirror and a CCD sensor and signal processing devices disposed in the laser device and the CCD detecting device. The laser device emits a laser beam to a surface level of a liquid, which reflects the beam to the CCD detecting device, and the curved mirror directs the reflected beam onto the CCD sensor. The shape of the curved mirror is determined by a polynomial curve function so as to linearly magnify a change in a height of the surface when the bounced beam reaches the CCD sensor. The liquid level detection device enables the position of the surface level of the liquid to be detectable in real time with high accuracy.
US08785896B2 Radioactive contaminant container
Disclosed is a radioactive contaminant container including a wall that defines a containing space for containing radioactive contaminants and shields at least a portion of radiation irradiated from the radioactive contaminants, and the wall has an outer shape of a hexagonal cylinder or a substantially hexagonal cylinder.
US08785894B2 Irradiation device having transition glass seal
An irradiation device is provided having a housing having an interior chamber and an infrared emitter arranged therein. The infrared emitter has an emitter tube made of high silica content glass having a round cross section and a defined outer diameter. Electrical connection elements are made of a metallic material and led out from the emitter tube through a seal. In order to provide the emitter with a long service life and potentially higher output, which is also suitable for being enclosed by a seal that separates the regions of different media, temperatures, or pressures, the emitter tube end also has a round cross section and the defined outer diameter. Between the electrical connection element and the emitter tube there is a seal containing at least one transition glass, which has a thermal expansion coefficient lying between that of the metallic material and that of the high silica content glass.
US08785891B2 Adaptive shade window for plasma operations
An observation window is provided for use with a spray booth during a spray coating process where the observation window is located in a position to permit an operator to observe the spray coating process. The observation window is controlled to provide light transmission in the window suitable for the specific spray process being performed. The control can be automatic or operator controlled. The window is adapted to have a different light transmission during different spray processes such as plasma spray and HVOF spray.
US08785890B2 Charged particle beam apparatus permitting high-resolution and high-contrast observation
A lower pole piece of an electromagnetic superposition type objective lens is divided into an upper magnetic path and a lower magnetic path. A voltage nearly equal to a retarding voltage is applied to the lower magnetic path. An objective lens capable of acquiring an image with a higher resolution and a higher contrast than a conventional image is provided. An electromagnetic superposition type objective lens includes a magnetic path that encloses a coil, a cylindrical or conical booster magnetic path that surrounds an electron beam, a control magnetic path that is interposed between the coil and sample, an accelerating electric field control unit that accelerates the electron beam using a booster power supply, a decelerating electric field control unit that decelerates the electron beam using a stage power supply, and a suppression unit that suppresses electric discharge of the sample using a control magnetic path power supply.
US08785880B2 Chromatic aberration corrector and electron microscope
The chromatic aberration corrector (100) has a first multipole element (110) for producing a first electromagnetic field and a second multipole element (120) for producing a second electromagnetic field. The first multipole element (110) first, second, and third portions (110a, 110b, 110c) arranged along an optical axis (OA) having a thickness and producing a quadrupole field in which an electric quadrupole field and a magnetic quadrupole field are superimposed. In the first and third portions (110a, 110c), the electric quadrupole field is set stronger than the magnetic quadrupole field. In the second portion (110b), the magnetic quadrupole field is set stronger than the electric quadrupole field. The second portion (110b) produces a two-fold astigmatism component that is opposite in sign to two-fold astigmatism components produced by the first portion (110a) and third portion (110c).
US08785878B2 Charged particle beam apparatus
An apparatus includes an irradiation device configured to irradiate an object with charged particle beams, a measurement device configured to measure a characteristic of each of charged particle beams, and a controller. The measurement device includes a plate including knife edges, and a sensor configured to detect a charged particle beam incident thereon via the plate. The controller causes one charged particle beam, selected from the charged particle beams, to perform a scan relative to the measurement device so that the one charged particle beam traverses at least two knife edges among the plurality of knife edges, and to generate correction information for correcting a measurement error of the measurement device due to deformation of the plate, based on an output from the sensor upon the scan.
US08785877B2 Method for monitoring fouling in a cooling tower
Fouling in the fill portion of a cooling tower is monitored by transmitting radiation through a cooling tower, detecting the amount of radiation that has penetrated the cooling tower, and calculating the density of the fill portion of the cooling tower based on the detected radiation. A higher than expected density indicates the presence of fouling on the fill portion of the cooling tower. A rate of fouling may be established by monitoring the density of the fill portion of the cooling tower over time.
US08785872B1 Imaging method and system
An example imaging system including a detector, a transconductance amplifier, a charge integrator, and a current mirror is disclosed. The detector is coupled to a first current and configured to accumulate charges in response to light or radiation. The transconductance amplifier is configured to receive a pixel voltage of the detector and generate a second current according to the pixel voltage, wherein the pixel voltage is associated with the accumulated charges and the first current. The charge integrator is configured to generate an output signal according to a third current. The current mirror is configured to generate the first current and the third current according to the second current so that the first current gradually decreases as the pixel voltage approaches a reference voltage.
US08785869B2 System and method for providing emission mammography
A system and method for providing emission mammography are provided. The system includes a first gamma emission detector and a second gamma emission detector. The first and second gamma emission detectors are configured to compress an object therebetween. The system further includes a radioactive transmission source. At least one of the first and second gamma emission detectors is configured to detect gamma ray photons from the radioactive transmission source.
US08785867B2 Radiation detector, imaging device and electrode structure thereof, and method for acquiring an image
The present invention discloses a radiation detector, an imaging device and an electrode structure thereof, and a method for acquiring an image. The radiation detector comprises: a radiation sensitive film, a top electrode on the radiation sensitive film, and an array of pixel units electrically coupled to the radiation sensitive film. Each pixel unit comprises: a pixel electrode (which is configured to collect a charge signal in a pixel area of the radiation sensitive film), a storage capacitor, a reset transistor, a buffer transistor, a column strobe transistor, and a row strobe transistor. The column strobe transistor and the row strobe transistor are connected in series between the buffer transistor and the signal line, and transfer the voltage signal of the corresponding pixel unit in response to a column strobe signal and a row strobe signal. The radiation detector may be used for, for example, X-ray digital imaging.
US08785864B2 Organic-scintillator compton gamma ray telescope
Apparatus and methods for imaging sources of gamma rays with a large area, comparatively low-cost Compton telescope (20). The Compton telescope (20) uses multiple layers (24) of low-cost organic solid plastic or liquid scintillator, arranged in large arrays of identical scintillator pixels (28). Photodiodes, avalanche photodiodes (30), or solid-state photomultipliers are used to read out the fluorescent pulses from scintillator pixels (28). Multiple scintillator pixels (28) are multiplexed into a few fast digitizers (80) and a few fast FPGA programmable digital microprocessors (78). Selection rule methods are presented for processing multiple near-simultaneous gamma ray collisions within the Compton telescope (28) to identify trackable events that yield gamma ray image data of interest. A calibration method achieves improved energy resolution along with (x,y) position information in pixels (28) made of organic scintillator materials with multiple photodetectors (30). Synchronization trigger signals are used from a pulsed neutron source (58) to maximize the signal-to-background ratio for prompt gamma neutron activation analysis (PGNAA) of objects at greater than 2 meters range, where such trigger signals are based on the estimated range to PGNAA sources and neutron time-of-flight.
US08785861B2 Controlling PCB glass fiber orientation to limit crosstalk in a sensor module
A proximity sensing device having a light emitting assembly including a light emitting device for proximity sensing positioned on a substrate and a light emitting lens positioned along a side of the light emitting device opposite the substrate and a light receiving assembly having a light receiving device positioned on the substrate and a receiving lens positioned along a side of the light receiving device opposite the substrate. A mid wall is positioned between the light emitting assembly and the light receiving assembly which includes a crosstalk controlling portion positioned between the light emitting lens and the light receiving lens that is configured to reduce optical crosstalk between the light emitting assembly and the light receiving assembly.
US08785849B2 Ultra high precision measurement tool
A focused ion beam device is described comprising a gas field ion source with an analyzer for analyzing and classifying the structure of a specimen, a controller for controlling and/or modifying the structure of the specimen according to the analysis of the analyzer, an emitter tip, the emitter tip has a base tip comprising a first material and a supertip comprising a material different from the first material, wherein the supertip is a single atom tip and the base tip is a single crystal base tip. Furthermore, the focused ion beam device has a probe current control and a sample charge control. A method of operating a focused ion beam device is provided comprising applying a voltage between a single emission center of the supertip and an electrode, supplying gas to the emitter tip, analyzing and classifying the structure of a specimen, and controlling the structure of the specimen.
US08785845B2 Method and system for operating a time of flight mass spectrometer detection system
Dual TDC-ADC detection systems for time of flight mass spectrometry are disclosed herein. Detection systems based upon TDC generally provide higher timing resolution as opposed to detection systems based upon ADC. However, ADC generally provides increased dynamic range over TDC. By combining TDC and ADC into a tandem detector, and adjusting performance parameters of the respective converter types, the dynamic range of the dual TDC-ADC detection can be extended beyond what either detector type could have achieved individually. Composite time of flight mass spectra can be generated by aggregating individual mass spectra acquired from multiple time-of-flight extractions, and selecting the number of time-of-flight extractions to ensure overlap between the ADC and TDC dynamic ranges in the dual TDC-ADC detector system.
US08785841B1 Scintillation detector package having radioactive window therein
A scintillator package includes a housing, with a scintillator in the housing to scintillate when struck by radiation. A window seals an end of the housing to permit light emitted during a scintillation to exit the housing. The window comprises a radioactive material that is non-scintillating, and this radioactive material may be naturally occurring, such as lutetium.
US08785834B2 Solid-state image sensor, control method for the same, and electronic device
There is provided a solid-state image sensor including a plurality of unit pixels each including a photoelectric transducer generating a charge corresponding to an amount of incident light and accumulating the charge therein, a first transfer gate transferring the charge accumulated in the photoelectric transducer, a charge holding region where the charge is held, a second transfer gate transferring the charge, a floating diffusion region where the charge is held to be read out as a signal, a charge discharging gate transferring the charge to a charge discharging part, and a structure including an overflow path formed in a boundary portion between the photoelectric transducer and the charge holding region.
US08785833B2 Image pickup system and image pickup method
An image pickup system that performs image pickup control of a rolling shutter type such that an all line exposure period and a non-all line exposure period are generated and controls a light source of illumination light to increase or decrease, in a first light adjustment mode, while maintaining a light amount of the illumination light in a first period during the all line exposure period at a predetermined level, a light amount of the illumination light during a second period including the all line exposure period other than the first period and the non-all line exposure period compared with an immediately preceding second period.
US08785831B2 Image sensors and methods with high speed global shutter pixels
An image sensor includes a plurality of pixels and a row driver. Each pixel includes a photodiode, a first transfer gate, a second transfer gate, a first storage node, and a second storage node. The row driver is configured to provide signals to the first transfer gate and the second transfer gate of each pixel such that charge is transferred from the photodiode to the first storage node through the first transfer gate while a signal representing charge stored at the second storage node is output from the pixel to a column readout line. The row driver is also configured to provide signals to the first transfer gate and the second transfer gate such that charge is transferred from the photodiode to the second storage node through the second transfer gate while a signal representing charge stored at the first storage node is output from the pixel.
US08785830B2 Photovoltaic assembly for use in diffuse weather conditions and related methods
A method includes collecting site specific data, collecting field data at a site of an array of photovoltaic members, determining a current tracked irradiance of the array of photovoltaic members, calculating predicted irradiance for multiple orientations based on the site specific data and the sensed field data, or sensing an actual irradiance for multiple orientations. The method further includes determining a maximum predicted irradiance from the calculated predicted irradiance or a maximum actual irradiance from the sensed irradiance. The method further includes comparing the maximum predicted irradiance or the maximum sensed irradiance with the current tracked irradiance, and re-orienting the array of photovoltaic members to an orientation having the maximum predicted or actual irradiance if the maximum predicted or actual irradiance is greater than the current tracked irradiance.
US08785829B2 Systems, circuits, and methods for reconfiguring solar cells of an adaptive solar power system
A back sheet comprises an interconnect circuit coupling a plurality of solar cell tiles. A tiled solar cell, comprising a solar cell and encapsulating and glass layers, is inserted into the solar cell tiles. Each solar cell is individually monitored and addressed through the use of the interconnect circuit. As such, each solar cell and the interconnect circuit may be programmed or reconfigured through reconfiguration of the interconnect circuit.
US08785827B2 Microwave field director structure with vanes having a conductive material thereon
A self-supporting field director for use in heating an article in a microwave oven is characterized by a plurality of vanes, each vane extending radially outwardly from a central axis and being angularly adjacent to two other vanes. The vanes are supported by a slotted central support member. Each vane has a substrate formed from an electrically non-conductive material. A portion of at least one of the first and second major surfaces is covered by an electrically conductive material.
US08785819B2 Device for heating products used in sexual activities
A heating device includes a housing, a thermally conductive receptacle, a cover, a heating element, a temperature sensor, a user interface and a power source. The thermally conductive receptacle is disposed within the housing and is accessible through an opening. The thermally conductive receptacle is sized to receive, completely contain and heat a container containing a product used in sexual activities. The cover is attached to the housing and is disposed over the opening to provide access to the thermally conductive receptacle and enclose the container containing the product. The heating element is disposed within the housing, and is connected to the thermally conductive receptacle. The temperature sensor is disposed within the housing and is connected to the heating element or the thermally conductive receptacle. The controller is disposed within the housing and is electrically connected to the heating element, the temperature sensor, and the user interface. The controller (a) activates the heating element in response to a signal from the user interface, and (b) deactivates the heating element and provides a status indicator via the user interface whenever the temperature sensor indicates a desired temperature of between 80 and 135 degrees Fahrenheit. The power source is disposed within the housing and is connected to the first heating element and the controller.
US08785817B2 Method and apparatus for wireless remote control communication of a welder
A method and apparatus of communicating control signals to a welding power source from a remote location includes a welding system operated by control signals transmitted by a wireless remote control that can be remotely located from the welding power source. A plurality of welding parameters in the welding system are set and adjusted in response to wireless command signals transmitted to a controller including a control transceiver located on the welding power source. In this regard, an operator is able to quickly and efficiently control a welding system from a remote location, with no more cables than are necessary to perform the intended task.
US08785813B2 Laser-based material processing methods and systems
Various embodiments may be used for laser-based modification of target material of a workpiece while advantageously achieving improvements in processing throughput and/or quality. Embodiments of a method of processing may include focusing and directing laser pulses to a region of the workpiece at a pulse repetition rate sufficiently high so that material is efficiently removed from the region and a quantity of unwanted material within the region, proximate to the region, or both is reduced relative to a quantity obtainable at a lower repetition rate. Embodiments of an ultrashort pulse laser system may include a fiber amplifier or fiber laser. Various embodiments are suitable for at least one of dicing, cutting, scribing, and forming features on or within a semiconductor substrate. Workpiece materials may include metals, inorganic or organic dielectrics, or any material to be micromachined with femtosecond, picosecond, and/or nanosecond pulses.
US08785811B2 System and method for efficient laser processing of a moving web-based material
Systems and methods are described for efficient laser processing of a moving web-based material. In one embodiment, a moving web is provided at a selected speed. A laser beam is generated having a focal point positioned to provide either a score or cut in the web. The focal point of the laser beam is moved at a speed less than the selected speed for a selected distance thereby producing a discreet score or cut in the web in the machine direction. The focal point is repositioned to form another discreet score or cut once the prior discreet score or cut is formed. The repositioned focal point is moved at a speed less than the selected speed for another selected distance. The step of repositioning is repeated to form a plurality of discreet scores or cuts in the web moving at the selected speed. The laser beam is therefore able to be generated using less power than would be needed to produce the same type of discreet score or cut if the focal point were stationary as the web is moved at the selected speed.
US08785810B2 Laser optical system, repair apparatus and method using the same
According to example embodiments, a laser optical system includes a laser generator, at least one scan module, an objective lens, a relay lens, a review optical system, and a control device. The laser generator is configured to generate a laser beam. The at least one scan module is configured to reflect the laser beam generated by the laser generator and to direct the laser beam in different directions. The objective lens is configured to focus the laser beam on a substrate. The relay lens is configured to guide the laser beam scanned by the at least one scan module to within an incident range of the objective lens. The review optical system is configured to monitor, in real time, repair of the substrate using the laser beam. The control device is configured to control the at least one scan module.
US08785806B2 Submerged arc welding method with multiple electrodes for steel material
Steel is subjected to multiple-electrode submerged arc welding with three or more electrodes in which a direct-current power source is used to supply current to a first electrode, the welding by the first electrode is carried out at a current density of 250 A/mm2 or more, preferably with a wire diameter of 3.2 mm or less and a weld current of 1,000 A or more, the welding by the second electrode is carried out at a current density of 150 A/mm2 or more, preferably with a weld current of 600 A or more, one of the interelectrode spacings is 23 mm or more on a surface of the steel, and the remaining interelectrode spacings are 20 mm or less.
US08785803B2 High voltage switch
A high voltage switch is provided, comprising a pair of electrodes housed within a high pressure gas vessel and separated by a nominal distance D. At least one of the electrodes is provided with raised surface features each having a radius of curvature that is significantly smaller than the electrode separation D. Preferably one of the electrodes is flat-faced. Preferred gas pressures within the pressure vessel are in the range 300 psi to 1200 psi. When used to switch voltages of several hundred kilovolts, an operational life for the electrodes of between 400 and 1000 hours has been achieved.
US08785791B2 Through wiring substrate and manufacturing method thereof
A through wiring substrate includes a substrate having a first face and a second face; and a through-wire formed by filling, or forming a film of, an electrically-conductive substance into a through-hole, which penetrates between the first face and the second face. The through-hole has a bend part comprising an inner peripheral part that is curved in a recessed shape and an outer peripheral part that is curved in a protruding shape, in a longitudinal cross-section of the through-hole, and at least the inner peripheral part is formed in a circular arc shape in the longitudinal cross-section.
US08785790B2 High strength through-substrate vias
A component includes a support structure having first and second spaced-apart and parallel surfaces and a plurality of conductive elements extending in a direction between the first and second surfaces. Each conductive element contains an alloy of a wiring metal selected from the group consisting of copper, aluminum, nickel and chromium, and an additive selected from the group consisting of Gallium, Germanium, Indium, Selenium, Tin, Sulfur, Silver, Phosphorus, and Bismuth. The alloy has a composition that varies with distance in at least one direction across the conductive element. A concentration of the additive is less than or equal to 5% of the total atomic mass of the conductive element, and a resistivity of the conductive element is between 2.5 and 30 micro-ohm-centimeter.
US08785789B2 Printed circuit board and method for manufacturing the same
Disclosed herein are a printed circuit board (PCB) and a method for manufacturing the same. The PCB includes a base substrate, a circuit layer formed on the base substrate and including a connection pad, a solder resist layer formed on an upper portion of the base substrate and having an opening exposing the connection pad, a metal post formed on upper portions of the connection pad and the solder resist layer and having a plurality of diameters, and a seed layer formed on the upper portion of the solder resist layer and inner walls of the opening along an interface of the metal post.
US08785788B2 Wiring board with built-in electronic component and method for manufacturing the same
A wiring board with a built-in electronic component includes a substrate having an opening portion and having a first surface and a second surface on the opposite side of the first surface, and an electronic component having a third surface and a fourth surface on the opposite side of the third surface and positioned in the opening portion of the substrate such that the third surface faces the same direction as the first surface of the substrate. The electronic component has a curved surface joining the fourth surface and a side surface of the electronic component, and the opening portion of the substrate has a tapered portion formed by a tapered surface of the substrate joining an inner wall of the opening portion and the first surface and tapering from the first surface toward the second surface.
US08785787B2 Metal-based circuit board
A metal-based circuit board, which reduces the influence of thermal expansion, is provided having a structure where an insulating layer A having a large coefficient of thermal expansion is sandwiched between insulating layers B having a small coefficient of thermal expansion. Such a structure allows the insulating layers B to contract and expand so as to suppress contraction and expansion of the insulating layer A and thereby reduce the stress in the direction of negating the stress. As a result, while warpage or distortion is suppressed to be minimal, the bonding strength of the upper and the lower layer is maintained, and degree of freedom for circuit design is not impaired, thereby providing a highly reliable circuit structure.
US08785779B1 Snap-in raceway
A method and apparatus having an elongate housing and connectors. The elongate housing has a channel configured to hold a number of lines. The connectors extend from a side of the elongate housing. The connectors are configured to engage channels formed in a surface of a structure such that the elongate housing is connected to the structure.
US08785776B2 Methods and systems for coupling busway components
An electrical power distribution system is described. The system includes a ground busbar including a first opening defined therein and a busway housing including a second opening defined therein. The system also includes a fastener sealing system that includes a fastener and at least one seal. The fastener is configured to extend through the first opening and the second opening and to couple the ground busbar to the busway housing. The ground busbar contacts the busway housing, forming a ground connection therebetween.
US08785773B1 Programmable electrical outlet and keyed lock box for connection therewith
The programmable electrical outlet and keyed lock box for connection therewith is designed to program the output of electricity through an electrical outlet while simultaneously securing a male prong of an electronic appliance inside of the keyed lock box. The programmable electrical outlet includes a display and a plurality of buttons to program the electrical outlet, and an electrical cord with GFCI circuitry integrated into the male plug. The keyed lock box is specifically designed to contain and lock inside the programmable electrical outlet and the male plug of the electronic appliance. The keyed lock box includes a window to enable viewing of the display of the programmable electrical outlet. The keyed lock box also includes a snooze button extension that aligns with a snooze button located on the programmable electrical outlet.
US08785772B2 Terminal box and terminal box fixing arrangement
A terminal box includes a box body having a bottom portion, a terminal portion fixed to the box body, a pressing portion, a holding portion and a slide mechanism The bottom portion has an opening portion capable of receiving a terminal inserted therein from the outside. The terminal portion is capable of establishing electric conduction between the terminal portion and the terminal upon contact therewith. The pressing portion is switchable between a contacting state in which the pressing portion clamps the terminal with the terminal portion for establishing electric conduction between the terminal portion and the terminal and a spaced state spaced apart from the terminal portion. The holding portion holds the pressing portion integrally and is slidable on the box body in the direction of movement of the pressing portion to/away from the terminal portion.
US08785768B2 Method for vertically grounding and leading down from outer side of composite material pole tower and pole tower thereof
A method for vertically grounding and leading down form an outer side of a composite pole tower and pole tower thereof, wherein the method includes the following steps: extending an upper metal cross arm from an extended line of at least one side of a ground wire cross arm, vertically leading down a ground down-leading wire from a distal end of the upper metal cross arm, connecting the ground down-leading wire to the pole tower via a lower metal cross arm at a distance under a lower lead, and grounding the ground down-leading wire along a tower body of the pole tower, wherein when an lower portion of the tower body is a metal pipe, the ground down-leading wire is selectively directly connected to the metal pipe via the lower metal cross arm. The method facilitates in compressing the width of the transmission corridor to a maximum extent as well as designing a lightning protection, preventing the ground down-leading wire from short-circuiting with the tower body, and realizing the insulation function of the composite material tower body. The manner of using unilateral ground down-leading wire saves material, and is economical and simple in structure.
US08785767B2 Method for fixing a photovoltaic cell connector on a surface of a photovoltaic cell, photovoltaic cell connector forming die, device for fixing a photovoltaic cell connector on a surface of a photovoltaic cell
In various embodiments, a method for patterning the surface of a solder-covered photovoltaic cell connector on the light-incidence side of a photovoltaic cell is provided. The method may include heating at least a part of the solder-covered photovoltaic cell connector which is in contact with the surface of the photovoltaic cell; patterning at least a part of the surface of the heated part of the solder-covered photovoltaic cell connector so that a predetermined surface pattern is formed; and cooling the photovoltaic cell connector by means of which the pattern is fixed on the solder-covered surface of the photovoltaic cell connector.
US08785764B2 Photoelectric conversion device
A photoelectric conversion device is disclosed. In one embodiment, the device includes i) first and second substrates facing each other, wherein first and second electrodes are formed on the first and second substrates, respectively and ii) an electrolyte inlet formed to pass through the first substrate and configured to receive an electrolyte. The device may further include an inlet sealing member connected to an external surface of the first substrate and outwardly extending from a top portion of the electrolyte inlet, wherein the top portion is formed in the external surface of the first substrate, and wherein the inlet sealing member comprises an encapsulation space being in fluid communication with the electrolyte inlet.
US08785763B2 Joined nanostructures and methods therefor
Nanostructures are joined using one or more of a variety of materials and approaches. As consistent with various example embodiments, two or more nanostructures are joined at a junction between the nanostructures. The nanostructures may touch or be nearly touching at the junction, and a joining material is deposited and nucleates at the junction to couple the nanostructures together. In various applications, the nucleated joining material facilitates conductivity (thermal and/or electric) between the nanostructures. In some embodiments, the joining material further enhances conductivity of the nanostructures themselves, such as by growing along the nanostructures and/or doping the nanostructures.
US08785760B2 System and method for applying a chain of effects to a musical composition
A method for applying audio effects to one or more tracks off musical compilation is disclosed. The method comprises identifying a first virtual musician to be associated with a first instrument track; identifying a first virtual producer to be associated with the first instrument track; applying a first series of effects to the first instrument track, the first series of effects being dependent upon the first virtual musician; and applying a second series of effects to the first instrument track, the second series of effects being dependent upon the first virtual producer.
US08785759B2 Electric keyboard musical instrument, method executed by the same, and storage medium
An electric keyboard musical instrument 10 includes: keys 32; third switches 36 that detect that the keys 32 are pressed down to a position x3; various switches 12 to 15 that receive a selection of a kind of tone; and a CPU 21 that executes generating a sound with a tone of the kind received by various switches 12 to 15 in response to the third switch 36 detecting that a key 32 is pressed down to a position x3. The CPU 21 changes a time from when the third switch 36 detects that a key 32 is pressed down to position x3 until sound generation is executed, according to a kind of tone received through the various switches 12 to 15.
US08785758B2 Electronic hi-hat cymbal controller
An electronic hi-hat cymbal controller is disclosed. The controller includes a hi-hat cymbal stand with a foot pedal configured and arranged to mechanically lift a control shaft. A lower cymbal is supported by the hi-hat cymbal stand. An upper cymbal is supported by the control shaft and oriented over the lower cymbal. And a position detector is configured and arranged to detect the position of the control shaft relative to the hi-hat cymbal stand.
US08785754B1 Inbred corn line SLN55
An inbred corn line, designated SLN55, the plants and seeds of the inbred corn line SLN55, methods for producing a corn plant, either inbred or hybrid, produced by crossing the inbred corn line SLN55 with itself or with another corn plant, and hybrid corn seeds and plants produced by crossing the inbred line SLN55 with another corn line or plant and to methods for producing a corn plant containing in its genetic material one or more transgenes and to the transgenic corn plants produced by that method. This invention also relates to inbred corn lines derived from inbred corn line SLN55, to methods for producing other inbred corn lines derived from inbred corn line SLN55 and to the inbred corn lines derived by the use of those methods.
US08785753B1 Hybrid corn variety 1692667
The invention provides seed and plants of the hybrid corn variety designated 1692667. The invention thus relates to the plants, seeds and tissue cultures of the variety 1692667, and to methods for producing a corn plant produced by crossing a corn plant of variety 1692667 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety 1692667.
US08785747B1 Hybrid corn variety 122971
The invention provides seed and plants of the hybrid corn variety designated 122971. The invention thus relates to the plants, seeds and tissue cultures of the variety 122971, and to methods for producing a corn plant produced by crossing a corn plant of variety 122971 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety 122971.
US08785743B1 Soybean cultivar 1000745
Disclosed is the seed of a novel soybean cultivar, designated 1000745, a sample of which is deposited under ATCC Accession No. PTA-121011. Also disclosed are plants, or parts thereof, grown from the seed of the cultivar, plants having the morphological and physiological characteristics of the 1000745 cultivar, and methods of using the plant or parts thereof in a soybean breeding program.
US08785742B1 Soybean cultivar 1000729
Disclosed is the seed of a novel soybean cultivar, designated 1000729, a sample of which is deposited under ATCC Accession No. PTA-121009. Also disclosed are plants, or parts thereof, grown from the seed of the cultivar, plants having the morphological and physiological characteristics of the 1000729 cultivar, and methods of using the plant or parts thereof in a soybean breeding program.
US08785739B2 Soybean variety A1026577
The invention relates to the soybean variety designated A1026577. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1026577. Also provided by the invention are tissue cultures of the soybean variety A1026577 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1026577 with itself or another soybean variety and plants produced by such methods.
US08785738B2 Soybean variety A1026547
The invention relates to the soybean variety designated A1026547. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1026547. Also provided by the invention are tissue cultures of the soybean variety A1026547 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1026547 with itself or another soybean variety and plants produced by such methods.
US08785737B2 Soybean variety A1026091
The invention relates to the soybean variety designated A1026091. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1026091. Also provided by the invention are tissue cultures of the soybean variety A1026091 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1026091 with itself or another soybean variety and plants produced by such methods.
US08785735B2 Soybean cultivar HI1019210
The present invention is in the field of soybean variety HI1019210 breeding and development. The present invention particularly relates to the soybean variety HI1019210 and its progeny, and methods of making HI1019210.
US08785728B2 AAD-12 event 1606 and related transgenic soybean lines
This invention relates to soybean event pDAB4472-1606 (Event 1606). This invention includes a novel aad-12 transformation event in soybean plants comprising a polynucleotide sequence, as described herein, inserted into a specific site within the genome of a soybean cell. This invention also relates in part to plant breeding and herbicide tolerant plants. In some embodiments, said event/polynucleotide sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins.
US08785727B2 Desaturase and method for the production of polyunsaturated fatty acids in transgenic organisms
The present invention relates to a polynucleotide from Emiliana huxleyi which codes for a desaturase and which can be employed for the recombinant production of polyunsaturated fatty acids. The invention furthermore relates to vectors, host cells and transgenic nonhuman organisms which comprise the polynucleotide according to the invention, and to the polypeptides encoded by the polynucleotide. The invention furthermore relates to antibodies against the polypeptide according to the invention. Finally, the invention also relates to production methods for the polyunsaturated fatty acids and for oil, lipid and fatty acid compositions and to their use as drugs, cosmetics, foodstuffs, feedstuffs, preferably fish food, or food supplements.
US08785722B2 Dominant gene suppression transgenes and methods of using same
Pairs of plants are provided in which complementing constructs result in suppression of a parental phenotype in the progeny. Methods to generate and maintain such plants, and methods of use of said plants, are provided, including use of parental plants to produce sterile plants for hybrid seed production. Also provided are regulatory elements for pollen-preferred expression of linked polynucleotides. Also provided are methods for identifying gene function, methods for testing allelic variants, and methods for repressing transmission of transgenes.
US08785715B2 Absorbent article with a slitted absorbent core
The invention relates to slit absorbent articles and the use of slits in absorbent materials to provide improved liquid intake rate, flexibility and softness compared to the unmodified material. The absorbent material, including superabsorbent materials, are particularly useful as absorbent cores in disposable absorbent articles such as diapers, incontinent products, sanitary napkins and the like.
US08785706B2 Addition of a base to enhance product yield in alkylation reactions
A process for making styrene including providing toluene, a co-feed, and a C1 source to a reactor containing a catalyst having acid sites and reacting toluene with the C1 source in the presence of the catalyst and the co-feed to form a product stream containing ethylbenzene and styrene, wherein the C1 source is selected from methanol, formaldehyde, formalin, trioxane, methylformcel, paraformaldehyde, methylal, dimethyl ether, and wherein the co-feed removes at least a portion of the acid sites on the catalyst. The co-feed can be selected from the group of aniline, amines, cresol, anisol, and combinations thereof.
US08785703B2 Process for preparing ethylene and propylene
The present invention provides a process for preparing ethylene and/or propylene, comprising the steps of contacting a stream comprising C4+ olefins with a zeolite-comprising catalyst at a temperature in the range of from 350 to 1000° C. and retrieving an olefinic product stream comprising: ethylene and/or propylene, and a C4+ hydrocarbon fraction, comprising paraffins, normal olefins and iso-olefins; The C4+ hydrocarbon fraction is recycled while part of the fraction is purged. The part of the C4+ hydrocarbon with is purged is treated to extract C4+ isoolefins as tert-alkyl ethers. At least part of tert-alkyl ethers are converted to further ethylene and propylene.
US08785702B2 Turbine and diesel fuels and methods for making the same
A process for making diesel and turbine fuels including, providing an effective amount of branched olefins, adding active heterogeneous acid catalyst(s) to said branched olefins to produce a solvent-free mixture, heating said solvent-free mixture greater than about 100° C. for a desired amount of time depending on various conditions, to produce C16 dimers/catalyst mixture, removing said catalysts from said dimers/catalyst mixture, and adding hydrogenation catalyst(s) to said dimers under hydrogen atmosphere to produce a mixture of stable fuels.
US08785701B2 Co-processing of diesel biofeed and kerosene range hydrocarbons
Processes are provided for producing a diesel fuel product having a sulfur content of 10 ppm by weight or less from feed sources that include up to 50% by weight of a biocomponent feedstock. The biocomponent feedstock is co-processed with a heavy oil feed in a severe hydrotreating stage. The product from the severe hydrotreatment stage is fractionated to separate out a diesel boiling range fraction, which is then separately hydrotreated.
US08785699B2 Methods of higher alcohol synthesis
Systems, catalysts, and methods are provided for transforming carbon based material into synthetic mixed alcohol fuel.
US08785698B2 Methods and apparatus for production of natural L-menthol
Embodiments are provided that provide for efficient production of highly pure natural I-menthol. In some embodiments, a method for preparing natural I-menthol involves providing crude mentha oil in a crystallizer and gradually reducing the temperature of the crystallizer in a step-wise manner, thereby producing highly pure crystals in less than two weeks. The methods disclosed herein are suitable for pharmaceutical GMP.
US08785696B2 Phosphorus compound and method for preparing the same
The present invention provides a phosphorus compound of formula (I). The phosphorus compound is prepared by reacting a compound of formula (II) with alkylene carbonate. As compared with the conventional phosphorus compounds as flame-resistant additives, the phosphorus compound of the present invention has not only a high pyrolysis temperature but also excellent solubility in most of the organic solvents with high or low polarity, and is therefore a suitable flame-resistant additive for use in thermosetting or thermoplastic resins.
US08785695B2 Method for purifying compounds containing amino groups
Method for purifying compounds (I) containing amino groups from a polar phase A, where (I) is converted by reaction with an aldehyde or ketone (II) into the corresponding imine (III) which is insoluble or sparingly soluble in the polar phase A, and then the imine (III) is converted to a nonpolar phase B and separated off from phase A, and then the compound containing amino groups is recovered from the imine (III).
US08785692B2 Substituted phenylamidines and the use thereof as fungicides
The present invention relates to oxime ether-, hydrazone- or azomethine-substituted phenylamidines of the general formula (I), to a process for their preparation, to the use of the amidines according to the invention for controlling unwanted microorganisms and also to a composition for this purpose, comprising the amidines according to the invention. Furthermore, the invention relates to a method for controlling unwanted microorganisms by applying the compounds according to the invention to the microorganisms and/or their habitat.
US08785689B2 Method for purifying difluoroacetic acid chloride
A method for purifying difluoroacetic acid chloride, including the step of bringing a difluoroacetic acid chloride composition that contains at least difluoroacetic acid fluoride into contact with calcium chloride at a temperature enabling reaction thereof thereby converting difluoroacetic acid fluoride into difluoroacetic acid chloride.
US08785687B2 For preparing surface-reacted calcium carbonate and its use
The present invention relates to an economic process for preparing surface-reacted calcium carbonate. The present invention further relates to a surface-reacted calcium carbonate having an increased specific BET surface area, and the use of a process for adjusting the specific BET surface area.
US08785679B2 Hydrophilic biocidal coatings
Hydrophilic, biocidal coating compositions and methods to make and use the compositions are disclosed. The coatings include compounds with quaternary amine polyethylene glycol groups and polyaminoalkyl biguanide groups as substituents. The compounds when incorporated in paints provide hydrophilic, self-cleaning and biocidal property to the coating.
US08785677B1 Organoleptic compound
The present invention is directed to a novel compound, but-2-enoic acid 1,2-dimethyl-butyl ester, and a method of improving, enhancing or modifying a fragrance formulation through the addition of an olfactory acceptable amount of but-2-enoic acid 1,2-dimethyl-butyl ester.
US08785674B2 Process for hydrogenation of halogenoalkenes without dehalogenation
A process for preparing a compound of formula VI wherein R1 and R6 is hydrogen, substituted or unsubstituted alkyl substituted or unsubstituted aryl, or substituted or unsubstituted aralkyl; R5 is B(OR2)(OR3), or wherein R2 and R3 independently from each other represent substituted or unsubstituted alkyl, substituted or unsubstituted aryl, or substituted or unsubstituted aralkyl; or R2 and R3 cooperatively form a part of a 5- to 10-membered fused or unfused ring, optionally a chiral 5- to 10-membered fused or unfused ring; X is selected from Cl, Br, I; and * indicates a chiral center; is described.
US08785671B2 6,13-dihalogen-5,14-dihydropentacene derivative and method for producing 6,13-substituted-5,14-dihydropentacene derivative using same
The present invention provides a 6,13-dihalogen-5,14-dihydropentacene derivative and a method for production thereof. Compounds (b) and (c) are reacted through cross-coupling reaction in the presence of a metal compound and a lithiating agent to synthesize compound (d), which is then halogenated to thereby obtain a 6,13-dihalogen-5,14-dihydropentacene derivative (compound (e)). [wherein X1 and X2 are each a halogen atom, and R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 are each a hydrogen atom, an optionally substituted C1-C20 hydrocarbon group, etc.]
US08785669B2 Taxane compounds, compositions and methods
The present invention provides a method for the preparation of orally available pentacyclic taxane compounds, as well as intermediates useful in their preparation.
US08785665B2 Surfactant-enabled transition metal-catalyzed chemistry
In one embodiment, the present application discloses mixtures comprising (a) water in an amount of at least 1% wt/wt of the mixture; (b) a transition metal catalyst; and (c) one or more solubilizing agents; and methods for using such mixtures for performing transition metal mediated bond formation reactions.
US08785663B2 Polymorphic forms of Lubiprostone
There is provided a crystalline form of Lubiprostone, termed APO-II and methods for making APO-II. APO-II is a polymorphic form of Lubiprostone.
US08785658B2 Pyrrole compounds that modulate HSP90 activity
The present invention relates to substituted pyrrole compounds and compositions comprising substituted pyrrole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted pyrrole compound of the invention, or a pharmaceutical composition comprising such a compound.
US08785656B2 Telescoping synthesis of 5-amino-4-nitroso-1-alkyl-1H-pyrazole salt
A telescoping synthesis of 5-amino-4-nitroso-1-alkyl-1H-pyrazole salt derivatives of formula (I), the compound (I) itself, and its use as an intermediate in the fabrication of 1-alkyl-4,5-diaminopyrazole salts of general formula (IX). The compounds of formula (IX) can be used as precursor dyes in oxidative hair dye compositions. R is a mono- or poly-substituted or unsubstituted, straight or branched, saturated or mono- or poly-unsaturated, alkyl group. HZ and HZ′ are organic or mineral acids.
US08785654B2 Method for production of N-(2-amino-1,2-dicyanovinyl)imidates, method for production of N-(2-amino-1,2-dicyanovinyl)formamidine, and method for production of aminoimidazole derivatives
A method for producing N-(2-amino-1,2-dicyanovinyl)imidates represented by the following formula (1-III) under low temperature conditions within a short period of time in high yield is provided. In addition, a method for producing N-(2-amino-1,2-dicyanovinyl)formamidine represented by the following formula (2-II) which is suitably applicable to a cyclization reaction for producing AlCN, AlCA or the like and which enhances yield of the cyclization reaction is provided. In addition, a method for producing aminoimidazole derivatives represented by the following formula (3-V) in high yield by using diaminomaleonitrile as a starting material is provided.
US08785653B2 (3-aryl-1H-1,2,4-triazol-5-yl)-linked heterocycle derivatives
This invention is directed to compounds of formula I having the structure which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable carrier. The present invention also provides processes for the preparation of the compounds of formula I. The present invention further provides a method of treating a subject suffering from a neurodegenerative disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention also provides a method of treating a subject suffering from a drug addiction comprising administering to the subject a therapeutically effective amount of a compound of formula I. The present invention further provides a method of treating a subject suffering from a psychiatric disorder comprising administering to the subject a therapeutically effective amount of a compound of formula I.
US08785652B2 Detection of hydrogen peroxide
The present invention provides compounds useful for detection of hydrogen peroxide and methods of using same.
US08785650B2 Methods for preparing 3-substituted-6-trifluoromethyl pyridines and methods for using 6-trichloromethyl halogenated pyridines
3-substituted-6-trifluoromethyl pyridines are useful synthetic intermediates in the preparation of the N-substituted (6-haloalkylpyridin-3-yl)alkyl sulfoximines, which are useful in forming potent insecticides. Methods of forming such 3-substituted-6-trifluoromethyl pyridines are disclosed. Also disclosed are methods of using 6-trichloromethyl halogenated pyridines to form 3-substituted-6-trifluoromethyl pyridines are disclosed.
US08785647B2 Pesticidal arylpyrrolidines
The invention is directed to arylpyrrolidines compounds which exhibit excellent insecticidal efficacy and which may be used as in the agrochemical field or in the vield of veterinary medicine. The compounds are represented by formula (I): wherein the respective substituents are defined in the specification.
US08785645B2 Method for synthesizing bio-based pyridine and picolines
The present invention relates to a method for synthesizing bio-based pyridine and picolines, said method including at least the following steps: a first step involving subjecting a glycerol filler, created from the methanolysis of vegetable oils or animal fats, to a dehydration reaction leading to acrolein; a second step involving partial condensation of the effluent from the first step so as to separate a water-rich flow as well as an acrolein-rich flow; and a third step involving reacting the acrolein from the preceding step with acetaldehyde in the presence of ammonia so as to obtain, by means of a condensation reaction, the bio-based pyridine and picolines.
US08785644B2 Processes for the preparation of 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione compounds
The present invention provides new processes for the preparation of unsubstituted and substituted 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione compounds which are useful, for example, for preventing or treating diseases or conditions related to an abnormally high level or activity of TNF-α. The invention can provide improved and/or efficient processes for the commercial production of unsubstituted and substituted 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione compounds, including, but not limited to, unsubstituted 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione.
US08785643B2 Substituted bicyclic aromatic compounds as S-nitrosoglutathione reductase inhibitors
The present invention is directed to novel substituted bicyclic aromatic compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.
US08785642B2 Process for preparing 6-substituted-1-(2H)-isoquinolinones and intermediate compound
The present invention relates to novel substituted phenyl compounds of the formula and to a process for making them. The compounds can be used as intermediates for making 6-substituted-1-(2H)-isoquinolinone derivatives.
US08785641B2 Synthesis of tripodal catechol derivatives having an adamantyl basic framework for functionalizing surfaces
The present invention describes tripodal catechol derivatives with an adamantyl basic framework for the functionalization of surfaces, methods for their production and use. The remaining fourth bridgehead position is easily suitable to be further functionalised via so-called click reactions, by way of example with biomolecules, dyes, radiomarkers, polyethylene glycol or active agents.The compounds according to the present invention have the general formula X-Ad[(CH2)n—YZ]3, wherein A stands for the adamantyl skeleton, X stands for a group —(CH2)p—R5, wherein p=0 to 10 and R5 is selected from —H, —NH2, —NO2, —OH, —SH, —O—NH2, —NH—NH2, —N═C═S—, —N═C═O—, —CH═CH2, —C≡CH, —COOH, —(C═O)H, —(C═O)R6Y stands for —CH2—, —CH═CH—, —C≡C—, —O—, —S—, —S—S—, —NH—, —O—NH—, —NH—O—, —HC═N—O—, —O—N═CH—, —NR1—, -aryl-, -heteroaryl-, —(C═O)—, —O—(C═O)—, —(C═O)—O—, —NH—(C═O)—, —(C═O)—NH—, —NR1—(C═O)—, —(C═O)—NR1—, —NH—(C═O)—NH—, —NH—(C═S)—NH—, R1 stands for an alkyl group, R6 for an alkyl, alkenyl, alkynyl, aryl or heteroaryl group, and Z stands for a catechol derivative.The production of the compounds occurs by reacting a compound X-Ad[(CH2)n—Y′]3 with a reagent Y″Z to the corresponding compound X-Ad[(CH2)n—YZ]3 and subsequently purifying the reaction product.Y′ and Y″ are hereby precursors of Y. The compounds according to formula (I) according to the present invention are suitable to be used in a method to functionalize surfaces. The X group of the compounds according to the present invention is suitable to be optionally coupled to an effector, for example, by means of click chemistry.
US08785640B2 Modulators of cystic fibrosis transmembrane conductance regulator
The present invention relates to modulators of cystic fibrosis transmembrane conductance regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using modulators of CFTR.
US08785638B2 Thieno [2, 3-B] pyridine derivatives as viral replication inhibitors
The present invention relates to a series of compounds having antiviral activity, more specifically HIV (Human Immunodeficiency Virus) replication inhibiting properties. The invention also relates to methods for the preparation of such compounds, as well as to novel intermediates useful in one or more steps of such syntheses. The invention also relates to pharmaceutical compositions comprising an effective amount of such compounds as active ingredients. This invention further relates to the use of such compounds as medicines or in the manufacture of a medicament useful for the treatment of animals suffering from viral infections, in particular HIV infection. This invention further relates to methods for the treatment of viral infections in animals by the administration of a therapeutic amount of such compounds, optionally combined with one or more other drugs having anti-viral activity.
US08785635B2 Cyclopamine analogs
The invention provides novel derivatives of cyclopamine having the following formula:
US08785634B2 Spiropiperidine prolylcarboxypeptidase inhibitors
Compounds of structural formula (I) are inhibitors of prolylcarboxypeptidase (PrCP). The compounds of the present invention are useful for the prevention and treatment of conditions related to enzymatic activity of PrCP such as abnormal metabolism, including obesity; diabetes; metabolic syndrome; obesity related disorders; and diabetes related disorders.
US08785629B2 Phosphonates synthons for the synthesis of phosphonates derivatives showing better bioavailability
Synthons for the synthesis of phosphonates prodrugs POM and POC, especially for direct Cross Metathesis.
US08785627B2 Copolymerizable methine and anthraquinone compounds and articles containing them
This invention relates to polymerizable ultraviolet light absorbers and yellow colorants and their use in ophthalmic lenses. In particular, this invention relates to polymerizable ultraviolet light absorbing methane compounds and yellow compounds of the methine and anthraquinone classes that block ultraviolet light and/or violet-blue light transmission through ophthalmic lenses.
US08785625B2 Compound having heterocyclic ring
The invention provides a novel oxazolidinone derivative represented by the formula (I): wherein Ring A, X1, Ring B and R1 are as described in the description, and an antibacterial agent containing the same.
US08785623B2 Magnetic nanoparticle cellulose material
The present invention relates to ferromagnetic materials based on nano-sized bacterial cellulose templates. More specifically, the present invention provides an agglomerate free magnetic nanoparticle cellulose material and a method of forming such magnetic nanoparticle cellulose material. Further, the magnetic nonoparticles are physically attached on the cellulose material and evenly distribute.
US08785618B2 Method of delivering RNA interference and uses thereof
The invention provides a method of RNA interference, which comprises contacting the cell with a fusion protein-double stranded RNA complex, the complex comprising the double stranded RNA segment containing a double stranded RNA of interest and a fusion protein, the fusion protein comprising (1) a targeting moiety, which will specifically binds to a site on a target cell, and (2) a binding moiety, which will bind to the double stranded RNA, wherein the double stranded RNA segment initiates RNA interference in the cell.
US08785615B2 Single molecule sensitive probes for detecting RNA
The various embodiments of the present disclosure relate generally to single molecule sensitive probes for detecting RNA, and more particularly to multivalent fluorescent probes for detecting a single molecule of RNA in a cell. The present invention includes a RNA imaging probe comprising: a multivalent core comprising a plurality of attachment sites; a plurality of RNA/DNA chimeric oligonucleotides having a specificity for a target RNA, wherein a RNA/DNA chimeric oligonucleotide is bound to an attachment site of the multivalent core; and a plurality of fluorophores, wherein a fluorophore is bound to the RNA/DNA chimeric oligonucleotide.
US08785614B2 Aberrantly methylated genes in pancreatic cancer
The present invention provides a method for detecting pancreatic carcinoma in a subject. The method includes contacting a nucleic acid-containing specimen from the subject with an agent that provides a determination of the methylation state of at least one gene or associated regulatory region of the gene and identifying aberrant methylation of regions of the gene or regulatory region, wherein aberrant methylation is identified as being different when compared to the same regions of the gene or associated regulatory region in a subject not having the pancreatic carcinoma, thereby detecting pancreatic carcinoma in the subject.
US08785613B2 P. pastoris pastoris promoters, and the use thereof to direct expression of proteins in yeast, preferably using a haploid mating strategy
Novel promoters which are derived from P. pastoris pastoris which are inducible or repressible under specific growth conditions are provided. These promoters are useful for regulating the expression of a desired structural gene, e.g., a mammalian polypeptide. Particularly preferred is the use of these novel promoters to regulate gene expression in polyploidal yeast such as diploidal P. pastoris produced by mating or spheroplast fusion.
US08785612B2 Sugarcane bacilliform viral (SCBV) enhancer and its use in plant functional genomics
Identification of new enhancer sequence has significant utility in the plant functional genomics. The sugarcane bacilliform badnavirus (SCBV) transcriptional enhancer has been identified. This enhancer can be used to increase the rate of transcription from gene promoters and in activation tagging experiments. A ten-fold increase in transcription was observed when a 4× array of the SCBV enhancer was placed upstream of a truncated form of the maize alcohol dehydrogenase minimal promoter. Methods of using the SCBV transcriptional enhancer are described, as are chimeric transcription regulatory regions, constructs, cells, tissues, and organisms that comprise one or more copies of the enhancer.
US08785610B2 Algal desaturases
Provided herein are exemplary isolated nucleotide sequences encoding polypeptides having desaturase activity, which utilize fatty acids as substrates.
US08785603B2 Antibodies to 25-hydroxyvitamin D2 and D3 and uses thereof
Provided herein are antigenic molecules that can be used to generate antibodies capable of binding to a vitamin D derivative, such as 25-hydroxyvitamin D2 and/or 25-hydroxyvitamin D3, or a 25-hydroxyvitamin D analog, such as a vitamin D-C22 immunogenic molecule or compound. Antibodies produced using these antigenic molecules, and related antigenic compounds, are also described. In addition, disclosed herein are methods for detecting vitamin D deficiency in a subject, methods for treating a subject suspected of having a vitamin D deficiency, methods for monitoring progression of vitamin D deficiency in a subject, and methods for monitoring treatment of vitamin D deficiency in a subject in need thereof. Also provided are methods and reagents for the detection or quantification of 25-hydroxyvitamin D2 and D3, methods for stabilizing vitamin D analogs, and methods for separating 25-hydroxyvitamin D2 and D3 from vitamin D binding protein in a biological sample.
US08785599B2 FcγRIIB—specific antibodies and methods of use thereof
The present invention relates to antibodies or fragments thereof that specifically bind FcγRIIB, particularly human FcγRIIB, with greater affinity than the antibodies or fragments thereof bind FcγRIIA, particularly human FcγRIIA. The present invention also provides the use of an anti-FcγRIIB antibody or an antigen-binding fragment thereof, as a single agent therapy for the treatment, prevention, management, or amelioration of a cancer, preferably a B-cell malignancy, particularly, B-cell chronic lymphocytic leukemia or non-Hodgkin's lymphoma, an autoimmune disorder, an inflammatory disorder, an IgE-mediated allergic disorder, or one or more symptoms thereof. The invention provides methods of enhancing the therapeutic effect of therapeutic antibodies by administering the antibodies of the invention to enhance the effector function of the therapeutic antibodies. The invention also provides methods of enhancing efficacy of a vaccine composition by administering the antibodies of the invention.
US08785596B2 Antigen constructs useful in the detection and differentiation of antibodies to HIV
Isolated HIV-1 Group O env polypeptides obtained from the HIV-1 isolate HAM112 are claimed, as well as (a) antigen constructs comprising fusions of one or more of each of HIV-1 Group O env polypeptides and HIV-1 Group M env polypeptide and (b) further antigen constructs containing additional Group O sequences and especially the gp41 IDR of isolate HAM112. Also claimed are polynucleotide sequences encoding the above, expression vectors comprising the same, host cells transformed thereby, and immunoassay methods and kits utilizing the antigen constructs of the invention.
US08785595B2 Functionalising reagents and their uses
Reagents and methods for functionalizing polypeptides with moieties poly (alkylene glycol) molecules and glycan groups are disclosed that are based on a functionalizing reagent which comprises a nitrogen containing heterocyclic aromatic ring having a vinyl substituent that is capable of reacting with one or more thiol groups that are naturally present, or have been introduced into, the polypeptide, for example by employing a thiol group of one or more cysteine residues. The functionalizing reagent is covalently linked to a poly (alkylene glycol) molecule, such as a polyethylene glycol (PEG) molecule, or a glycan group so that the reaction between the vinyl group and the thiol group in the polypeptide covalently links the polypeptide to the poly (alkylene glycol) molecule and/or the glycan group.
US08785590B2 Polyamide
The invention provides a polyamide having a dicarboxylic acid unit containing a decahydronaphthalenedicarboxylic acid unit in an amount of 60 mol % or more, and a diamine unit.
US08785588B2 Tin-containing polyurethane resin
A tin-containing polyurethane resin having a melting temperature of 40 to 180° C., measured by DSC at a heating rate of 10 K/min and prepared by carrying out a condensation reaction between a diorganotin compound and carboxyl groups of a carboxyl-functional polyurethane resin, wherein the molar ratio between the tin and the carboxyl groups is 1:2-20; and liquid coating compositions containing solid particles of the tin-containing polyurethane resin.
US08785587B2 Polyurea- and/or polyurethane-polyorganosiloxane compounds
The invention relates to novel polyurea- and/or polyurethane polyorganosiloxane compounds, processes for the preparation thereof, and their use and novel reactive 1- or 2-component systems and cured compositions therefrom. The compounds preferably contain repeating units of the formula (2): in the polyurea- and/or polyurethane polyorganosiloxane backbone. The polyurea- and/or polyurethane polyorganosiloxane compounds can also contain polyether segments in the backbone.
US08785585B2 Temporary adhesive composition, and method of producing thin wafer
A temporary adhesive for which temporary adhesion and subsequent detachment are simple. The temporary adhesive composition includes: (A) an organopolysiloxane having a weight-average molecular weight of at least 15,000, obtained by a hydrosilylation reaction between (A1) and (A2) described below, and (B) an organic solvent having a boiling point of not more than 220° C., wherein (A1) is an alkenyl group-containing organopolysiloxane having a weight-average molecular weight exceeding 2,000, comprising 35 to 99 mol % of T siloxane units and 1 to 25 mol % of M siloxane units, and in which alkenyl groups bonded to silicon atoms represent at least 2 mol % of all the organic groups bonded to silicon atoms, and (A2) is a specific organohydrogenpolysiloxane having at least two silicon atom-bonded hydrogen atoms or a specific hydrosilyl group-containing compound.
US08785584B2 Propylene-based terpolymers for films
A propylene/ethylene/1-hexene terpolymer containing from 1.0 wt % to 2.5 wt %, of ethylene derived units and from 2.0 wt % to 4.0 wt % of 1-hexene derived units, the sum of the amounts of propylene, ethylene and 1-.hexene derived units being 100, having the following features: a) the amount (Wt %) of 1-hexene (C6) and the amount (Wt %) of ethylene (C2) fulfill the following relation: C2<−0.18C6+2.86; b) Polydispersity index (PI) ranging from 2 to 10; c) melting temperature ranging from 125° C., to 139° C.; d) solubility in xylene at 25° C. below 10 wt %; e) melt index (MFR) of from 4 to 6 g/10′ dg/min, according to ISO method 1133; and f) crystallization temperature ranging from 85° C. to 100° C.
US08785583B2 Process for continuously producing water-absorbing polymer particles
A process for continuously producing water-absorbing polymer particles by polymerizing a monomer solution comprising acrylic acid and/or salts thereof, wherein the acrylic acid supplied has a dimeric acrylic acid content of at least 0.02% by weight and the dimeric acrylic acid content is kept essentially constant.
US08785581B2 Fluoroelastomer, curable composition and cured rubber article
A noncrystalline fluoroelastomer which is a copolymer consisting essentially of vinylidene fluoride and a fluoromonomer represented by the general formula (1): CH2═CFRf  (1) wherein Rf is a straight or branched fluoroalkyl group containing 1 to 12 carbon atoms, and has a vinylidene fluoride units/fluoromonomer units mol ratio of 78/22 to 22/78 and a glass transition temperature of not higher than 25° C.
US08785578B2 Paper coatings of amphiphilic, non-water-soluble comb-branched (meth)acrylic polymers, uses thereof
Polymers, paper coating compositions, and coated paper.
US08785575B2 Process for the preparation of ethylene propylene copolymers
A polymerization process comprising contacting under polymerization conditions ethylene and at least propylene to obtain a copolymer containing from 96% by mol to 71% by mol of ethylene derived units, in the presence of a catalyst system obtainable by contacting: b) at least a metallocene compound of formula (I), b) alumoxane or a compound capable of forming an alkyl metallocene cation; and optionally c) an organo aluminum compound; wherein the groups R1-R4, L, M and W are described in the text.
US08785564B2 Resin material
A resin material contains a polymer of a composition containing an isocyanate and an acrylic resin having OH-group-containing side chains in which a proportion of OH-group-containing side chains each having 6 or more carbon atoms relative to all of the OH-group-containing side chains is about 76 mol % or more and about 100 mol % or less.
US08785560B2 Employing pretreatment and fluorination of fluoropolymer resin to reduce discoloration
Process for reducing thermally induced discoloration of fluoropolymer resin produced by polymerizing fluoromonomer in an aqueous dispersion medium to form aqueous fluoropolymer dispersion and isolating said fluoropolymer from the aqueous medium by separating fluoropolymer resin in wet form from the aqueous medium and drying to produce fluoropolymer resin in dry form. The process comprises: pretreating the aqueous fluoropolymer dispersion and/or the fluoropolymer resin in wet or dry form; and exposing the fluoropolymer resin in dry form to fluorine.
US08785558B2 Process for the production of condensation polymers via in-reactor chain extension and products thereof
Methods for forming high molecular weight chain-extended condensation polymers are disclosed. The methods include adding a chain extender during the polymerization process of a condensation polymer to provide a chain-extended condensation polymer, wherein the chain extender comprises a polymerization product of at least one epoxy-functional (meth)acrylic monomer, and at least one styrenic and/or (meth)acrylic monomer.
US08785557B2 Use of aqueous hybrid binders for gloss paints
The present invention relates to the use of aqueous hybrid binders for producing coating compositions, more particularly in high-gloss coating materials (high-gloss paints), and also to a process for their preparation with low residual monomer content.
US08785554B2 Crystalline block composites as compatibilizers
Embodiments of the invention provide crystalline block composites and their use as compatibilizers. The crystalline block composites comprise i) a crystalline ethylene based polymer; ii) a crystalline alpha-olefin based polymer and iii) a block copolymer comprising a crystalline ethylene block and a crystalline alpha-olefin block.
US08785551B2 Catalyst composition comprising shuttling agent for ethylene multi-block copolymer formation
A composition for use in forming a multi-block copolymer, said copolymer containing therein two or more segments or blocks differing in chemical or physical properties, a polymerization process using the same, and the resulting polymers, wherein the composition comprises the admixture or reaction product resulting from combining: (A) a first metal complex olefin polymerization catalyst, (B) a second metal complex olefin polymerization catalyst capable of preparing polymers differing in chemical or physical properties from the polymer prepared by catalyst (A) under equivalent polymerization conditions, and (C) a chain shuttling agent.
US08785547B2 Toughening cross-linked thermosets
Grafted triglycerides comprising an acrylated triglyceride grafted with a fatty acid residue containing 4 to 28 carbon atoms. Also described are methods for making a grafted triglyceride and for curing a material selected from vinyl esters and unsaturated polyesters and mixtures thereof and optionally a reactive diluent. The method includes the steps of mixing a grafted triglyceride of the present invention with a material selected from vinyl esters, unsaturated polyesters and mixtures thereof to form a mixture, and curing the mixture to form a cured resin system. A cured resin system comprising a cured product obtained by the foregoing method and composites containing the cured product and a filler or reinforcing material are also disclosed. This method also includes use of the grafted triglycerides to make toughened resin and composite systems with reduced hazardous air pollutants without significantly reducing the glass transition temperature and significantly increasing the viscosity.
US08785545B2 Refrigerator interior liner
A refrigerator interior liner can be made of a composition including a monovinylaromatic polymer matrix having an average molecular weight in weight Mw above 150,000 g/mol; rubber particles; and low- Mw plasticizers. The rubber particles can have an RPS volume of about 8.5 μm, a monomodal distribution, a swell index above 13.8, and an RPVF of at least 39%. The composition can be prepared by forming a polymerizable mixture including a monovinylaromatic monomer, and dissolving a viscous rubber in the polymerizable mixture. A free radical initiator and a chain transfer agent can be contacted with the polymerizable mixture at conditions whereby phase inversion subsequently occurs. The chain transfer agent can produce an increase of the rubber to PS phase viscosity ratio within the inversion reactor. Polymerization can be continued until a monovinylaromatic polymer matrix having rubber particles dispersed therein is obtained.
US08785538B2 Electromagnetic wave shielding thermoplastic resin composition and plastic article including the same
Disclosed herein are an electromagnetic wave shielding thermoplastic resin composition and a plastic article including the same. The electromagnetic wave shielding thermoplastic resin composition comprises about 100 parts by weight of a thermoplastic resin comprising a polycarbonate resin, a polyester resin, or a combination thereof, about 1 to about 30 parts by weight of stainless steel fiber, and about 0.01 to about 10 parts by weight of carbon nanotubes.
US08785536B2 Use of acrylic polymers neutralized by lithium as dispersing agents or grinding aid agents of mineral materials in an aqueous medium
The invention pertains to the use of a homopolymer of acrylic acid or a copolymer of acrylic acid with a water-soluble monomer, as a dispersing agent or grinding aid agent in a method for manufacturing an aqueous suspension of mineral materials through dispersion and/or grinding, characterized in that the carboxylic groups of said agent are fully or partially neutralized by the lithium ion and in that it exhibits a viscosity index of between 0.01 and 0.08.
US08785535B2 Fibrous basic magnesium sulfate powder and method for producing same
A fibrous basic magnesium sulfate powder which does not contain CO2 in an amount of more than 0.15% by mass, or a fibrous basic magnesium sulfate powder which has a ratio of the infrared absorption within the wave number range of 1,400-1,440 cm−1 relative to the infrared absorption within the wave number range of 3,180-3,530 cm−1 of 0.005 or less. The fibrous basic magnesium sulfate powders exhibit improved physical property-improving effect when dispersed in a resin material.
US08785534B2 Use of polyamides that are resistant to corrosion and stress cracking
The use of thermoplastic molding materials comprising A) 10 to 98.8% by weight of a mixture formed from a1) 40 to 70% by weight of nylon-6,6 or nylon-4,6 or nylon-6 or mixtures thereof, a2) 30 to 60% by weight of a polyamide having a ratio of methylene to amide groups of 7 to 12, B) 1 to 50% by weight of a fibrous or particulate filler, C) 0.1 to 3% by weight of a lubricant, D) 0.05 to 3% by weight of a heat stabilizer, E) 0 to 40% by weight of further additives, where the sum of the percentages by weight A) to E) and a1) and a2) adds to 100%, for production of stress cracking- and corrosion-resistant moldings.
US08785532B2 Diamino-alcohol compounds, their manufacture and use in coatings applications
A new class of compounds, namely diamino alcohols, is described, along with a process for their production and their use as dispersing additives for coating formulations.
US08785529B2 Nucleating agents for polyolefins based on metal salts
Described herein are novel metal salts capable as nucleating agents for polyolefins. The present invention relates to such salts synthesized by reacting potassium hydroxide with carboxylic acids and further, to the achievement of high crystallization temperatures in polypropylene compositions upon dispersal therein of formulations containing one or more of the said metal salts.
US08785527B2 Synthetic resin composition and automotive interior/exterior material comprising the same
Disclosed are a synthetic resin composition having more excellent weather resistance and an automotive interior/exterior material comprising the synthetic resin composition.Specifically disclosed are a synthetic resin composition comprising, per 100 parts by mass of a synthetic resin, as Component (A) a hindered amine compound represented by the following general formula (I): (wherein R represents an alkyl group having 1 to 30 carbon atoms or the like; and n represents an integer of 1 to 6) or the following general formula (II): (wherein R represents an alkyl group having 1 to 30 carbon atoms or the like) in an amount of 0.01 to 20 parts by mass, and as Component (B) a sulfur-containing antioxidant in an amount of 0.01 to 20 parts by mass; and an automotive interior/exterior material comprising the synthetic resin composition.
US08785525B2 Thermosetting light-reflecting resin composition, optical semiconductor element mounting board produced therewith, method for manufacture thereof, and optical semiconductor device
There is provided a thermosetting light-reflecting resin composition that has a high level of various characteristics required of optical semiconductor element mounting boards, such as optical properties and thermal discoloration resistance, provides high releasability during molding such as transfer molding, and allows molding processes to be performed continuously. There are also provided a highly-reliable optical semiconductor element mounting board and an optical semiconductor device each produced with the resin composition, and methods for efficient production thereof. A thermosetting light-reflecting resin composition is prepared and used, which includes (A) an epoxy resin, (B) a curing agent, (C) a curing catalyst, (D) an inorganic filler, (E) a white pigment, (F) an additive, and (G) a release agent as major components, wherein the resin composition, after curing, has a diffuse reflectance of 80% or more at a light wavelength of 400 nm; and the resin composition is possible to perform transfer molding 100 times or more continuously.
US08785523B2 Phosphorus loaded particles and methods for their preparation and use
A flame retardant additive includes red phosphorus adsorbed into a porous carrier. The carrier may be mixed with white phosphorus above its melting point (41° C.), so that liquid phosphorus is pulled into the pores of the carrier by capillary action. The phosphorus-loaded carrier may be heated above 250° C. to convert the white phosphorus to red phosphorus. The resulting red phosphorus-loaded carrier may retain flame retardant activity, and may also be protected from the environment for easier handling and formulation. By employing a carrier of a suitably small particle size, it is practical to incorporate the flame retardant red phosphorus-loaded carrier in thin films.
US08785522B2 Low-permittivity resin composition
The present invention relates to a low-dielectric resin composition having sufficiently low dielectric constant and dissipation factor, a low-dielectric film formed of the low-dielectric resin composition, processes for producing the low-dielectric resin composition and the low-dielectric film, and a coating agent for low-dielectric films. According to the present invention, there are provided (1) a low-dielectric resin composition including hollow silica particles having an average particle size of from 0.05 to 3 μm and a BET specific surface area of less than 30 m2/g, and a matrix resin in which the hollow silica particles are dispersed; (2) a low-dielectric film including the low-dielectric resin composition; (3) a process for producing the low-dielectric resin composition which includes the steps of preparing hollow silica particles (A) containing air inside thereof or core/shell type silica particles (B) in which a material capable of being dissipated by calcination to form hollow portions therein is encapsulated; calcination the hollow silica particles (A) or the core/shell type silica particles (B) at a temperature higher than 950° C. to prepare hollow silica particles (C); and dispersing the hollow silica particles (C) in a matrix resin-forming material to prepare a dispersion of the particles; and (4) a coating agent for low-dielectric films including the hollow silica particles, and a matrix resin-forming material in which the hollow silica particles are dispersed.
US08785519B2 Anionic latex as a carrier for bioactive ingredients and methods for making and using the same
This invention relates to latex compositions that incorporate at least one bioactive component such as an antibacterial or an antifungal agent, and methods for making and using such latex compositions. The latex compositions disclosed herein can be prepared by the emulsion polymerization of the latex component monomers in the presence of the at least one bioactive component.
US08785515B2 Sensitizer for cationic photoinitiators
Polycyclic aromatic compounds of formula (I) having at least two conjugated aromatic rings at least one of which has a substituent comprising a cyclic carbonate group can be used as sensitizers for cationic photoinitiators, especially iodonium compounds, and may also function as monomers in cationically initiated radiation curable compositions, especially coating compositions, such as printing inks and varnishes.
US08785513B2 Fiber-reinforced composites and method for the manufacture thereof
The present invention relates to fiber-reinforced composites, particularly application-oriented composites useful in dental and medical applications/appliances, such as fiber reinforced dental composites, and to a method for the manufacture thereof. Particularly the invention concerns random glass fiber-reinforced restorative composite resins with semi-interpenetrating polymer network matrix and their use in dental applications like cavity fillings, core composites, provisional and semi-permanent crown and bridge composite, cements and adhesives.
US08785511B2 Silicone-containing polyurethane foam
Low density silicone-containing polyurethane foams with excellent surface characteristics are prepared by reacting a foamable composition containing a siloxane of the formula and an isocyanate, in the presence of at least one blowing agent.
US08785510B2 Alkenyl aromatic foam with low solubility hydrofluorocarbon
Prepare a closed-cell alkenyl aromatic polymer foam by an extrusion process using a blowing agent composition that contains at least 30 weight-percent of the chlorine-free hydrofluorocarbon blowing agent such that the foam has a density of 48 kilograms per cubic meter or less, contains more than 50 weight-percent styrene-acrylonitrile copolymer based on total polymer weight and at least eight weight-percent of a chlorine-free hydrofluorocarbon blowing agent that has a lower solubility in polystyrene than 1,1,2,2-tetrafluoroethane (HFC-134).
US08785509B2 Superinsulation with nanopores
This invention relates to the field of thermal insulation. In particular, the invention describes superinsulation articles having a desired porosity, reduced pore size and cost-effective methods for manufacturing such articles. In one aspect of the present invention, the article may comprise a material system with at least about 20% porosity. In a further aspect of the invention, an article may comprise greater than about 25% of nanopores having a pore size no greater than about 1500 nanometers in its shortest axis.
US08785508B2 Pre-expanded polypropylene resin beads and process for producing same
The present invention provides pre-expanded polypropylene resin beads comprising (A) a glycerin monoester of a C6 to C24 fatty acid and/or a polyglycerin monoester of a C6 to C24 fatty acid and (B) a glycerin diester of a C6 to C24 fatty acid(s) and/or a polyglycerin diester of a C6 to C24 fatty acid(s), in such a manner that a weight ratio [=(A)/(B)] between (A) and (B) in the polypropylene resin particles is 1.3 or more but 10 or less, and a total content [=(A)+(B)] is 0.3 parts by weight or more but 5 parts by weight or less with respect to 100 parts by weight of the polypropylene resin. The resin particles can be excellently used in in-mold foaming, without requiring washing with a chemical like nitric acid or metaphosphate soda, and can provide a polypropylene resin in-mold foamed product with good antistatic properties.
US08785504B2 4-hydroxy benzoate derivatives for use in the treatment of infection, inflammation or pain
A compound of the general formula (I) is provided for use in the topical treatment of infection, inflammation and/or pain: wherein R1 independently represents a methylene group, an ethylene group or a straight or branched chain C3 to C6 alkylene group; R2 independently represents a hydrogen atom, a methyl group, an ethyl group or a straight or branched chain C3 to C20 alkyl group; x represents 0 or an integer from 1 to 4 and y represents 0 or an integer from 1 to 4, wherein the sum of x and y is 4; and Z represents a hydrogen atom or (HOR1)yR2xN+; compositions including the compound; use of the compound in the manufacture of a medicament; and methods of medical treatment including the topical application of the compound.
US08785501B2 Anti-cancer tamoxifen-melatonin hybrid ligand
A particularly constructed tamoxifen-melatonin hybrid ligand gives new and unexpectedly improved results in the prevention and treatment of cancer, particularly breast cancer. The hybrid ligand comprises either tamoxifen or 4-hydroxytamoxifen and also melatonin, with the tamoxifen or 4-hydroxytamoxifen and melatonin's being linked by an unsubstituted C2-C6 alkyl linker between the tamoxifen amine and the carbonyl of melatonin.
US08785496B2 Method of using beta-hydroxy-beta-methylbutyrate for treating disease-associated wasting
The present invention relates to methods for the prevention and treatment of chronic inflammatory diseases, cancer, and involuntary weight loss. In the practice of the present invention patients are enterally administered HMB alone or alternatively in combination with eicosapentaenoic (20:5 ω-3), FOS, carnitine and mixtures thereof. HMB may be added to food products comprising a source of amino-nitrogen enriched with large neutral amino acids such as leucine, isoleucine, valine, tyrosine, threonine and phenylalanine and substantially lacking in free amino acids.
US08785495B2 Compositions including beta-hydroxy-beta-methylbutyrate
The present invention relates to methods for the prevention and treatment of chronic inflammatory diseases, cancer, and involuntary weight loss. In the practice of the present invention patients are enterally administered HMB alone or alternatively in combination with eicosapentaenoic (20:5 ω-3), FOS, carnitine and mixtures thereof. HMB may be added to food products comprising a source of amino-nitrogen enriched with large neutral amino acids such as leucine, isoleucine, valine, tyrosine, threonine and phenylalanine and substantially lacking in free amino acids.
US08785494B2 Calcium sensing receptor modulating compounds and pharmaceutical use thereof
The invention relates to novel calcium-sensing receptor (CaSR) modulating trifluoromethylphenylene cyclopentylene compounds represented in formula (I) and derivatives thereof, to said compounds for use as a medicament, to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases with said compounds, and to the use of said compounds in the manufacture of medicaments.
US08785486B2 Imidazo[1,2-A]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors
The present invention relates to novel compounds, in particular novel imidazo[1,2-a]piridine derivatives according to Formula (I). The compounds according to the invention are positive allosteric modulators of metabotropic receptors-sub-type 2 (‘mGluR2’) which are useful for the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which the mGluR2 subtype of metabotropic receptors is involved. In particular, such diseases are central nervous system disorders selected from the group of anxiety, schizophrenia, migraine, depression, and epilepsy. The invention is also directed to pharmaceutical compositions and processes to prepare such compounds and compositions, as well as to the use of such compounds for the prevention and treatment of such diseases in which mGluR2 is involved.
US08785480B2 Functionalized pyridine N-oxides and processes for the preparation of the same
In one embodiment, processes for the preparation of certain functionalized pyridine N-oxides are provided. In one form, the functionalized pyridine N-oxides include 2-substituted-5-(1-alkylthio)alkyl-pyridine N-oxides. Further embodiments, forms, objects, features, advantages, aspects, and benefits shall become apparent from the description.
US08785478B2 Viral polymerase inhibitors
The present invention relates to viral polymerase inhibitors of formula (I) or salts, N-oxides, solvates, hydrates, racemates, enantiomers or isomers thereof, processes for their preparation and their use in the treatment of Flaviviridae viral infections such as Hepatitis C virus (HCV) infections.
US08785477B2 Hexahydropyrrolo[3,4-b]pyrrole derivatives, preparation methods and pharmaceutical uses thereof
Hexahydropyrrolo[3,4-b]pyrrole derivatives, preparation methods and pharmaceutical uses thereof are provided. Specifically, dipeptidyl peptidase IV inhibitors presented by following formula (I) are provided. Such compounds can be used for treating or preventing the diseases associated with dipeptidyl peptidase IV, such as diabetes, obesity and hyperlipemia. The compounds presented by formula (I) and pharmaceutically acceptable salts thereof, a method for preparing a pharmaceutical composition thereof and their uses in the manufacture of medicaments for treating or preventing the disease associated with dipeptidyl peptidase IV are provided.
US08785475B2 Lipoic acid derivatives
Lipoic acid derivatives and pharmaceutical formulations containing lipoic acid derivatives are useful in the treatment and prevention of disease characterized by disease cells that are sensitive to lipoic acid derivatives.
US08785470B2 Heterocyclic compounds and uses thereof
Compounds and pharmaceutical compositions that modulate kinase activity, including PI3 kinase activity, and compounds, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with kinase activity, including PI3 kinase activity, are described herein.
US08785469B2 Method of treating atherogenic dyslipidemia
The present invention relates to methods of treating metabolic syndrome, Type 2 diabetes mellitus, atherogenic dyslipidemia and/or obesity. The present invention also relates to methods of restoring the incretin effect, to restoring physiologic control of glucagon levels, to restoring first-phase insulin secretion, and to restoring the physiologic glucose-dependent insulin secretion. The methods of the present invention comprise administration of a selective κ-receptor antagonist, such as guanidinylated naltrindole (GNTI), or pharmaceutically acceptable derivatives thereof to a subject in need thereof.
US08785464B2 Pyrimidine derivatives that inhibit FAK/PTK2
The present invention includes compounds of general formula (1) wherein A, X, R1 and R2 are defined as in claim 1, which are suitable for the treatment of diseases characterized by excessive or abnormal cell proliferation, and their use for preparing a medicament having the above-mentioned properties.
US08785462B2 5-hydroxypyrimidine-4-carboxamide derivative
The present invention provides a compound which enhances the production of erythropoietin. The present invention provides a compound represented by formula (1): [wherein, R1: formula (1A): [wherein, R4 and R5: H, halogen, or alkyl; R6: H, halogen, alkyl, or the like; R7: substitutable hydroxyalkyl, substitutable hydroxyhalo alkyl, substitutable alkoxyalkyl, or the like; substituent group α: oxo, hydroxy, amino, or the like; ring Q1: a monocyclic heterocyclic group; ring Q2: a monocyclic hydrocarbon ring group, or a monocyclic heterocyclic group; ring Q3: a monocyclic hydrocarbon ring group, or a monocyclic heterocyclic group; X: a single bond, methylene, ethylene, or the like]; R2: alkyl, or methylsulfanyl; and R3: H, or methyl], or the like.
US08785461B2 Process for preparing bosentan
The present invention relates to a novel intermediate useful in the preparation of bosentan and to processes for the preparation of said intermediate and bosentan. The invention further relates to compositions comprising bosentan prepared according to the processes of the invention and their use in the treatment of endothelin-receptor mediated disorders.
US08785460B2 Tricyclic compounds and use thereof
There is provided a compound of the formula (I′): wherein x is a nitrogen or CRx, Rx is a hydrogen, etc., R1 is an optionally substituted hydrocarbon group, etc., R2 is an optionally substituted hydrocarbon group, etc., ring A is 5- to 8-membered heterocyclic ring, etc., and each of Y1, Y2 and Y3 is an optionally substituted carbon or a nitrogen, etc.; or a salt thereof or a prodrug thereof, which have CRF receptor antagonistic activity and use thereof.
US08785456B2 Substituted isoquinolin-1(2H)-ones, and methods of use thereof
Chemical entities that modulate PI3 kinase activity, pharmaceutical compositions containing the chemical entities, and methods of using these chemical entities for treating diseases and conditions associated with P13 kinase activity are described herein.
US08785455B2 Polymorph of linagliptin benzoate
The present invention relates to a novel polymorph of Linagliptin benzoate and to methods for its preparation. Furthermore the present invention relates to the use of the novel polymorph for the preparation of a medicament. In addition the present invention relates to pharmaceutical compositions comprising an effective amount of the novel polymorph of Linagliptin benzoate.
US08785447B2 Use of dopamine D3 receptor ligands for the production of drugs for treating renal function disorders
The invention relates to the use of dopamine D3 receptor ligands for the production of drugs for treating renal function disorders.
US08785446B2 Treating post-seizure patients
Patients are subject to a post-seizure treatment regime to separately inhibitor consecutive targets of an epileptogenic cascade comprising neurotransmitter receptor signaling, kinase/phosphatase activity, protein translation, and apoptosis or inflammation.
US08785445B2 7-phenoxychroman carboxylic acid derivatives
Compounds of Formula I: (I) in which A, A1, R1, R7a, R7b, R8 and R10 have the meanings given in the specification, are DP2 receptor inhibitors useful in the treatment of useful in the treatment and prevention of immunologic diseases, allergic diseases such as asthma, allergic rhinitis and atopic dermatitis, and other inflammatory diseases mediated by prostaglandin D2 (PGD2). The compounds of Formula I may also be useful in treating diseases or medical conditions involving the Th2 T cell via production of IL-4, IL-5 and/or IL-13.
US08785443B2 Methods of using prodrugs of methyl hydrogen fumarate and pharmaceutical compositions thereof
Prodrugs of methyl hydrogen fumarate, pharmaceutical compositions comprising prodrugs of methyl hydrogen fumarate, and methods of using prodrugs of methyl hydrogen fumarate and pharmaceutical compositions thereof for treating diseases such as psoriasis, asthma, multiple sclerosis, inflammatory bowel disease, and arthritis are disclosed.
US08785442B2 Compound as antagonist of lysophosphatidic acid receptor, composition, and use thereof
The present invention relates to a compound as antagonist of LPA receptor, and a pharmaceutical composition comprising the same. The present invention also relates to the use of the compound and the composition, and a method of using the compound to treat, prevent or diagnose diseases, disorders or conditions associated with one or more of the LPA receptors.
US08785436B2 1,3-oxazines as BACE 1 and/or BACE2 inhibitors
The present invention provides compounds of formula I having BACE1 and/or BACE2 inhibitory activity, their manufacture, pharmaceutical compositions containing them and their use as therapeutically active substances. The active compounds of the present invention are useful in the therapeutic and/or prophylactic treatment of e.g. Alzheimer's disease and type 2 diabetes.
US08785433B2 Quinoline derivatives as PI3 kinase inhibitors
Invented is a method of inhibiting the activity/function of PI3 kinases using quinoline derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of quinoline derivatives.
US08785428B2 Vermin poison
Use of an orally or nasally available formulation of Tretazicar for poisoning vermin. An orally available or nasally available formulation of Tretazicar, wherein in the orally available formulation the Tretazicar is protected from acid hydrolysis, and provided that the formulation is not solid Tretazicar in a gelatin capsule. A formulation of Tretazicar in which the Tretazicar is protected from acid hydrolysis, wherein the formulation is present in a liquid form. A combination of Tretazicar and bait. A method of poisoning vermin comprising making available to the vermin an orally or nasally available formulation of Tretazicar and allowing the vermin to ingest or inhale the formulation of Tretazicar.
US08785426B1 Testosterone gel compositions and related methods
Described are gel compositions containing active pharmaceutical ingredient such as testosterone, solvent, and thickener, the gel compositions being useful for transdermal administration of the active ingredient to a patient, and related methods. Certain embodiments of the gel composition specifically exclude Hsieh enhancer.
US08785420B2 Combination/association of adapalene and benzoyl peroxide for treating acne lesions
Acne lesions, whether of inflammatory and/or non-inflammatory type, are simultaneously or sequentially treated and their number reduced, via daily topical regimen, with the combination or association of adapalene or pharmaceutically acceptable salt thereof and benzoyl peroxide (BPO).
US08785417B2 Absorbent hydrophobic boronate galactomannan complexes and process for producing same
Absorbent boronate-galactomannan complexes comprising a hydrophobic group are disclosed. The boronate-galactomannan complexes are solid materials capable of gel forming upon contacting with liquids. The boronate-galactomannan complexes are particularly suitable for absorbing liquids.
US08785416B2 Sulphated disaccharides for the treatment of neurodegenerative and/or neurovascular diseases
The present invention relates to the use of a series of sulphated disaccharides for the preparation of a medicament for the treatment or prevention of a neurodegenerative and/or neurovascular disease, of a traumatic brain injury or of a traumatic spinal cord injury. The present invention also relates to the use of said sulphated disaccharides for the preparation of a neuroprotective medicament or of an antioxidant medicament. The neurodegenerative and/or neurovascular diseases are preferably: Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis and stroke.
US08785407B2 Antisense antiviral agent and method for treating ssRNA viral infection
The invention provides antisense antiviral compounds and methods of their use in inhibition of growth of viruses of the picornavirus, calicivirus, togavirus and flavivirus families, as in treatment of a viral infection. The antisense antiviral compounds have morpholino subunits linked by uncharged phosphorodiamidate linkages interspersed with cationic phosphorodiamidate linkages.
US08785405B2 Compounds for treating cancer and other diseases
This invention provides a method of synthesizing new active compounds for pharmaceutical uses including cancer treatment, wherein the cancers comprise breast, leukocytic, liver, ovarian, bladder, prostatic, skin, bone, brain, leukemia, lung, colon, CNS, melanoma, renal, cervical, esophageal, testicular, spleenic, kidney, lymphatic, pancreatic, stomach and thyroid cancers. This invention is an anti adhesion therapy which uses the compound as a mediator or inhibitor of adhesion proteins and angiopoietins. It inhibits excess adhesion and inhibits cell attachment. It modulates angiogenesis. The compounds also use as mediator of cell adhesion receptor, cell circulating, cell moving and inflammatory diseases.
US08785402B2 Compositions and assays for treatment and diagnosis of helicobacter pylori infection and conditions
Methods of diagnosing Helicobacter pylori infection or associated conditions are based in part on the correlation of the presence of a α-L-fucosidase 2 marker with the infection. Methods and compositions for treating or preventing Helicobacter pylori infection or associated conditions are based in part on administering an α-L-fucosidase 2 inhibitor to an infected subject or a subject at risk of developing the infection.
US08785398B2 Methods of treatment using CTLA4 mutant molecules
The present invention provides soluble CTLA4 mutant molecules which bind with greater avidity to the CD80 and/or CD86 antigen than wild type CTLA4 or non-mutated CTLA4Ig. The soluble CTLA4 molecules have a first amino acid sequence comprising the extracellular domain of CTLA4, where certain amino acid residues within the S25-R33 region and M97-G107 region are mutated. The mutant molecules of the invention may also include a second amino acid sequence which increases the solubility of the mutant molecule.
US08785397B2 Cosmetic use of apolipoprotein D type proteins
The subject of the present invention is the use, in particular the cosmetic and/or therapeutic use, of the apolipoprotein D, of polypeptides derived from this protein or of analogues thereof, of a nucleic sequence encoding such a polypeptide or of an agent modulating the activity or of the expression of such a polypeptide, in particular for stimulating terminal epithelial differentiation.The invention also relates to the use of the protein apolipoprotein D, of polypeptides derived from this protein or of analogues thereof, or of a nucleic sequence encoding such a polypeptide as a marker for evaluating the state of the epidermis.
US08785388B2 TAT-BH3 methods for treating arthritis
The present invention is directed to compositions and methods for treating immune system mediated disease. In particular, certain embodiments of the present invention use BH3 mimetic therapy as an efficacious treatment of the effector phase of RA wherein the compositions and methods of the present invention markedly reduce the level of the Bcl-2 antagonist protein Bim present in RA synovial tissue as compared to control patients. Therefore, the present invention involves restoring the function of Bim in order to ameliorate inflammatory arthritis. In connection therewith, systemic delivery of a peptide to the BH3 domain of Bim effectively inhibits the development of K/B×N serum transfer-induced arthritis which closely resembles the effector phase of RA.
US08785386B2 Benzazepine derivatives useful as vasopressin antagonists
The present invention provides a benzazepine compound that can maintain for a long period of time the blood level of tolvaptan enabling to provide the desired pharmaceutical effects. The benzazepine compound of the present invention is represented by general formula (1) wherein R1 represents a —CO—(CH2)n—COR2 group (wherein n is an integer of 1 to 4, and R2 is (2-1) a hydroxy group; (2-2) a lower alkoxy group optionally substituted with a hydroxy group, a lower alkanoyl group, a lower alkanoyloxy group, a lower alkoxycarbonyloxy group, a cycloalkyloxycarbonyloxy group, or 5-methyl-2-oxo-1,3-dioxol-4-yl; or (2-3) an amino group optionally substituted with a hydroxy-lower alkyl group), or the like.
US08785382B2 Lipid therapy
A method including introducing into a blood stream a delipidated high density lipoprotein (HDL) and a bioactive agent. A composition including a delipidated high density lipoprotein (HDL) and an auxiliary agent in a form suitable for delivery into a blood vessel. A composition including Apo A1 comprising a hydrophobic ligand suitable to interact with cell surface binding sites. A composition including Apo A1 and an agent selected to one of increase the ATP-binding cassette protein 1 (ABCA1) transporter expression in macrophages and protect ABCA1 from thiol-mediated degradation.
US08785377B2 Tetrazolyl macrocyclic hepatitis C serine protease inhibitors
The present invention relates to compounds of Formula I, II, III or IV, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising a compound of the present invention.
US08785376B2 Isolation, identification, and uses of antifungal compounds
In one aspect, the invention relates to isolated compounds useful as antifungal agents, for example, compounds having a structure represented by a formula: wherein R1 is hydrogen or hydroxyl; wherein R2 is hydrogen or xylose; and wherein R3 and R4 are each hydrogen or together oxygen, or a pharmaceutically acceptable salt thereof; methods of isolating and purifying same; pharmaceutical compositions comprising same; agricultural compositions comprising same; and methods of treating and/or preventing fungal infections using same. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
US08785373B2 Agents capable of downregulating an MSF-A-dependent HIF-1alpha and use thereof in cancer treatment
Methods and pharmaceutical compositions for the treatment of cancer or acute ischemia are provided. Also provided are methods of identifying agents capable of preventing the formation of or dissociating the MSF-A-HIF-1alpha protein complex, and methods of determining the prognosis of an individual having cancer by identifying the presence or absence of such a protein complex.
US08785372B2 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof
Provided are 1-aryl-5-alkyl pyrazole compounds, of formula (I): wherein: R1 is hydrogen, cyano, halogen, R8, formyl, —C(O)R8, —C(O)OR8, —C(O)NR9R10, or —C(S)NH2; R2 is R8 or —S(O)mR11; R3 is methyl, ethyl or C1-C4 haloalkyl; R4, R5 and R7 are independently hydrogen, halogen, alkyl, haloalkyl, cyano or nitro; R6 is halogen, alkyl, haloalkyl, alkoxy, haloalkyloxy, cyano, nitro, —C(O)R12, —S(O)nR12 or SF5; Z is a nitrogen atom or C—R13; R8 is alkyl, haloalkyl, cycloalkyl or halocycloalkyl; R9 is hydrogen, alkyl, haloalkyl or alkoxy; R10 is hydrogen, alkyl, haloalkyl or alkoxy; R11 is alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl or cycloalkyl; R12 is alkyl or haloalkyl; R13 is hydrogen, halogen, cyano, nitro, alkyl, haloalkyl, alkoxy or haloalkoxy; m is 0, 1 or 2; and n is 0, 1 or 2; or a salt thereof, the method of making compounds of formula (I) and the use of these compounds against ectoparasites, endoparasites and pests.
US08785371B2 Drug delivery of temozolomide for systemic based treatment of cancer
The present invention relates to methods of drug delivery for the treatment of a condition or disease, such as cancer. In one embodiment, the invention provides a method of preparing a multifunctional nanoconjugate of temozolomide (TMZ) by conjugating TMZ in its hydrazide form to a polymalic acid platform. In another embodiment, the polymalic acid platform is conjugated to a monoclonal antibody to transferrin receptor, a trileucine (LLL) moiety, and/or a polyethylene glycol (PEG) moiety. The present invention relates to methods of drug delivery for the treatment of a condition or disease, such as cancer. In one embodiment, the invention provides a method of preparing a multifunctional nanoconjugate of temozolomide (TMZ) by conjugating TMZ in its hydrazide form to a polymalic acid platform. In another embodiment, the polymalic acid platform is conjugated to a monoclonal antibody to transferrin receptor, a trileucine (LLL) moiety, and/or a polyethylene glycol (PEG) moiety.
US08785368B2 Solid soap comprising trimethylglycine
The object of the present invention is to improve the solidification point and the hardness of a soap of the fatty acid soap series wherein a large amount of myristic acid is blended. The solid soap of the present invention to achieve the above-described object is characterized by comprising a fatty acid soap and 1 to 8 mass % of betaine, and in that the content of myristic acid is 50 mass % or more in the total fatty acid of the fatty acid soap.
US08785367B2 Cleansing sheet
A cleansing sheet including a nonwoven sheet impregnated with a cleaning agent, the cleaning agent containing 99.80 wt % to less than 99.95 wt % of purified water and more than 0.05 wt % to 0.20 wt % of a bactericidal preservative, the bactericidal preservative including more than 0.025 wt % to 0.10 wt % benzalkonium chloride, more than 0.0025 wt % to 0.01 wt % iodopropynyl butylcarbamate, and more than 0.0225 wt % to 0.09 wt % glycol, based on the total weight of the cleaning agent taken as 100 wt %. The cleaning sheet can be applied to the delicate skin of infants or the sensitive skin of elderly people.
US08785365B2 Alpha-amylase variants stabilized against dimerization and/or multimerization, method for the production thereof, and detergents and cleansers containing these alpha-amylase variants
The present invention relates to α-amylase variants that are stabilized to dimerization and/or multimerization, in particular at elevated temperatures or high pH, by point mutagenesis of positively polarized or charged or neutral surface amino acids to give more negatively polarized or charged amino acids. The invention further relates to methods of increasing the stability of an α-amylase to dimerization and/or multimerization brought about by electrostatic interactions whereby at least one amino acid residue on the surface of the starting molecule, which makes a neutral or positively polar or charged contribution to the electrostatic potential of said molecule, is replaced with a more negatively polar or negatively charged amino acid residue. The α-amylase variants obtained thereby exhibit better stability to influences of the solvent, increased processivity, and are suited for numerous industrial areas of use, in particular as active ingredients in detergents and cleansers.
US08785364B2 Liquid laundry detergents comprising a silicone anti-foam
Dual-usage aqueous liquid detergent compositions having suds compatability and improved cleaning, said composition containing from about 1% to about 60%, by weight of the composition, of a surfactant system wherein said surfactant system contains at least 35%, by weight of the surfactant system, of alkylethoxysulfate; from 0% to about 10%, by weight of the surfactant system, of nonionic surfactant; from 0% to about 10%, by weight of the surfactant system, of soap; further contains from about 0.001% to about 4.0%, by weight of the composition, of an anti-foam selected from organomodified silicone polymers with aryl or alkylaryl substituents combined with silicone resin and the primary filler is modified silica; and mixtures thereof; and contains from about 0.01% to about 2.5%, by weight of the composition, of a structurant.Methods of using such detergent compositions for laundering textiles.
US08785360B1 Method and system for color changing contact lens solution
A used contact lens is placed in a contact lens receptacle. An aqueous composition is added to the contact lens receptacle, the aqueous composition capable of changing from a first appearance to a second appearance in response to an interaction with the used contact lens after a predetermined period of time.
US08785357B2 Composition containing heterocyclic compounds and a method of lubricating an internal combustion engine
The present Invention relates to the use of a compound in a lubricating composition as an engine oil antiwear and/or extreme pressure agent, wherein the compound is a heterocycle having a hydrocarbyl group containing 6 to 40 carbon atoms, wherein the heterocycle is either (i) a heterocycle compound having a functional group selected from the group consisting of at least one of an ester, an amide, a salt and an acid, or (ii) a pyrimidine.
US08785356B2 Method for the production of a lightweight magnesium silicate proppant and a proppant
The invention relates to oil and gas industry, i.e. techniques for making proppants designed to be used as propping agents in oil and gas recovery by the method of formation hydraulic fracturing. A method for the production of a lightweight magnesium silicate proppant, the method comprises heat processing of a magnesium-containing component—a source of magnesium oxide, its co-grinding with a silica-containing component, pelletizing of the batch prepared, sintering and sieving of the pellets prepared, wherein the batch comprises (in terms of calcined substance), in % by weight: SiO2-6 4-72, MgO-11-18, natural impurities—remainder, wherein the heat processing is carried out at temperature not more than 1080 degrees C. A lightweight magnesium silicate proppant is characterized in that the proppant is produced by said method. At least one of the group: serpentine, brucite, caustic magnesite, talc may be used said magnesium-containing component. Said components may comprise serpentine gravel and quartz-feldspar sand at the following ratio, wt. %: serpentine gravel—30-40, quartz-feldspar sand—60-70. The sintering is performed at temperature 1140-1190 degrees C.
US08785351B2 Herbicidal compositions containing bentazon and ALS inhibitor and ACCase inhibitor
Herbicidal compositions comprising (a) bentazon-sodium and (b) an ALS inhibitor and (c) an ACCase inhibitor controls susceptible and resistant weeds in crops, e.g., rice, wheat, barley, oats, rye, sorghum, corn/maize, pastures, grasslands, rangelands, fallowland, turf, tree and vine orchards and IVM, but also additionally in ALS and ACC'ase tolerant crops.
US08785348B2 Method of preparing carrier to separate nucleic acids, carrier and micro channel to separate nucleic acids, and method and apparatus for separating nucleic acids
The present disclosure relates to a method and apparatus for separating nucleic acids. A carrier may include a porous microbead having cation-exchangeable groups attached to the surface of the porous microbead. Capturing chains modified with positively charged functional groups and having a base sequence complementary to a target nucleic acid chain sequence are immobilized on to the surface of the porous microbead. In various embodiments, capturing chains are immobilized on to the surface of the porous microbead through an ion exchange bond or a covalent bond with the cation-exchangeable groups of the porous microbead. In some cases, the porous microbead has a number of through pores adapted to permit a solution to pass rapidly through the through pores and a number of diffusive pores adapted to permit a solute of the solution to diffuse into the diffusive pores. A solution having a target nucleic acid chain corresponding to the target nucleic acid chain sequence of the capturing chains may be passed through a channel that is packed with porous microbeads so as to result in hybridization of the capturing chain and the target nucleic acid chain. The porous microbeads may be structured such that the pressure in the channel upon passing of the solution through the channel does not build significantly.
US08785347B2 Gulf oil spill underwater oleophilic hydrophobic oil-capturing water permeable drag-net
An underwater oleophilic hydrophobic oil-capturing water permeable drag-net with the porous oil-capturing water-repelling and water-permeable component positioned in the back of and connected to the drag-net that can be dragged vertically through the underwater oil spill area of the Gulf to remove oil is presented. The invention is made of various sizes depending on the area of the oil spill area; including 100 ft high (north to south), 100 ft wide (east to west) and 10 ft deep (front to back). The net mesh-like material is made from threads and wires knotted, twisted, and woven to form a regular pattern with fine spaces between the threads with each strand of a metal, plastic, wire and fiber net-type material made of and covered with organic and inorganic Oleophilic hydrophobic and superhydrophobic, oil attracting and oil bonding molecules, materials or sorbents including Superhydrophobic materials. The underwater drag-net collects large amounts of oil from the Gulf and reduces the negative impact of the Gulf oil spill on the Gulf and its shores.
US08785345B2 Method for preparing hydrorefining catalyst
A method for preparing hydrorefining catalyst comprises the following steps: (1) mixing an aqueous ammonia solution with a polyamine complexing agent to form a mixed solvent; (2) adding a cobalt salt to the mixed solvent, dissolving the cobalt salt, and then adding a molybdenum salt and optional salts of other active components, and dissolving them to prepare an impregnating solution; and (3) impregnating a support with the impregnating solution, followed by aging, drying, and activating the impregnated support to form a hydrorefining catalyst. The hydrorefining catalyst prepared by this method has good activity, selectivity and stability in use.
US08785334B2 Select transistor, method for making select transistor, memory device, and method for manufacturing memory device
A select transistor for use in a memory device including a plurality of memory transistors connected in series includes a tunnel insulating layer formed on a semiconductor substrate, a charge storage layer formed on the tunnel insulating layer, a blocking insulating layer formed on the charge storage layer and configured to be irradiated with a gas cluster ion beam containing argon as source gas, a gate electrode formed on the blocking insulating layer, and a source/drain region formed within the semiconductor substrate at both sides of the gate electrode.
US08785332B2 Method and apparatus for plasma dicing a semi-conductor wafer
The present invention provides a method for plasma dicing a substrate. The method comprising providing a process chamber having a wall; providing a plasma source adjacent to the wall of the process chamber; providing a work piece support within the process chamber; placing the substrate onto a support film on a frame to form a work piece work piece; loading the work piece onto the work piece support; providing a cover ring disposed above the work piece; generating a plasma through the plasma source; and etching the work piece through the generated plasma.
US08785327B2 Method of manufacturing semiconductor device
According to one embodiment, a method of manufacturing a semiconductor device, includes forming first layer on first and second regions in substrate, first layer having first width in first region and having larger dimension than first width in second region, forming first sidewall on first layer, forming second layer covering first sidewall in the second region and forming third layer having second width smaller than first width on the side face of first sidewall having second width after removing first layer, forming second and third sidewalls having second width so that second and third sidewalls is adjacent to first sidewall across third layer by second width in first region and across second and third layers by second interval larger than second width in the second region.
US08785323B2 Method of forming an interconnect structure having an enlarged region
A method of forming an interconnect structure that may reduce or eliminate stress induced voids is provided. In an embodiment, a via is formed below a conductive line to provide an electrical connection to an underlying conductive region. The conductive line includes a widened region above the via. The widened region serves to reduce or eliminate stress induced voids between the via and the underlying conductive region. In another embodiment, one or more redundant lines are formed extending from a conductive region, such as a contact pad, such that the redundant line does not electrically couple the conductive region to an underlying conductive region. In a preferred embodiment, the redundant lines extend from a conductive region on a side adjacent to a side having a conductive line coupled to a via.
US08785320B2 Structure and process for metallization in high aspect ratio features
A high aspect ratio metallization structure is provided in which a noble metal-containing material is present at least within a lower portion of a contact opening located in a dielectric material and is in direct contact with a metal semiconductor alloy located on an upper surface of a material stack of at least one semiconductor device. In one embodiment, the noble metal-containing material is plug located within the lower region of the contact opening and an upper region of the contact opening includes a conductive metal-containing material. The conductive metal-containing material is separated from plug of noble metal-containing material by a bottom walled portion of a U-shaped diffusion barrier. In another embodiment, the noble metal-containing material is present throughout the entire contact opening.
US08785316B2 Methods for forming semiconductor materials by atomic layer deposition using halide precursors
Methods of depositing a III-V semiconductor material on a substrate include sequentially introducing a gaseous precursor of a group III element and a gaseous precursor of a group V element to the substrate by altering spatial positioning of the substrate with respect to a plurality of gas columns. For example, the substrate may be moved relative to a plurality of substantially aligned gas columns, each disposing a different precursor. Thermalizing gas injectors for generating the precursors may include an inlet, a thermalizing conduit, a liquid container configured to hold a liquid reagent therein, and an outlet. Deposition systems for forming one or more III-V semiconductor materials on a surface of the substrate may include one or more such thermalizing gas injectors configured to direct the precursor to the substrate via the plurality of gas columns.
US08785314B2 Etch bias homogenization
Methods and memory devices formed using etch bias homogenization are provided. One example method of forming a memory device using etch bias homogenization includes forming conductive material at respective levels over a substrate. Each respective level of conductive material is electrically coupled to corresponding circuitry on the substrate during patterning of the respective level of conductive material so that each respective level of conductive material has a homogenized etch bias during patterning thereof. Each respective level of conductive material electrically coupled to corresponding circuitry on the substrate is patterned.
US08785313B2 Method of manufacturing device having a blocking structure
A method of manufacturing a semiconductor device, and the method includes forming a stack of a work function layer, a blocking structure, and a metal cap layer sequentially on a substrate. The forming of the blocking structure includes sequentially depositing at least a metal diffusion prevention layer over the work function layer and an electrical performance enhancement layer over the metal diffusion prevention layer before forming the metal cap layer. The electrical performance enhancement layer includes a TiN layer having a Ti/N ratio greater than 1.
US08785311B2 Film forming method, semiconductor device, manufacturing method thereof and substrate processing apparatus therefor
In a method for forming a stacked substrate of a MOS (Metal Oxide Semiconductor) structure including an oxide film serving as a gate insulating film formed on a semiconductor material layer having a film or substrate shape; and a conductive film serving as a gate electrode formed on the oxide film, a polysilane film on the semiconductor material layer is formed by coating a polysilane solution on a surface of a substrate to which the semiconductor material layer is exposed. A film containing metal ions is formed on the polysilane film by coating a metal salt solution thereon, and the polysilane film and the film containing metal ions are respectively modified into a polysiloxane film and a film containing fine metal particles to form the stacked substrate.
US08785309B2 Spatial orientation of the carbon nanotubes in electrophoretic deposition process
A new method of electrophoretic nanotube deposition is proposed wherein individual nanotubes are placed on metal electrodes which have their length significantly exceeding their width, while the nanotube length is chosen to be close to that of the metal electrode. Due to electrostatic attraction of individual nanotube to the elongated electrode, every nanotube approaching the electrode is deposited along the electrode, since such an orientation is energetically favorable. This method offers opportunity to produce oriented arrays of individual nanotubes, which opens up a new technique for fabrication and mass production of nanotube-based devices and circuits. Several such devices are considered. These are MESFET- and MOSFET-like transistors and CMOS-like voltage inverter.
US08785302B2 Crystal silicon film forming method, thin-film transistor and display device using the crystal silicon film
A crystal silicon film forming method according to the present invention includes: forming a metal film; forming an insulating film on the metal film, and forming a crystal silicon film made of polycrystal Si on the insulating film. In the forming of an insulating film, the insulating film is formed within a film thickness range of 160 nm to 190 nm. The forming of a crystal silicon film includes forming an amorphous silicon film made of a-Si on the insulating film, within a film thickness range of 30 nm to 45 nm, and forming the crystal silicon film from the amorphous silicon film by irradiating the amorphous silicon film with a light of a green laser.
US08785301B2 Method of cleaning silicon carbide semiconductor
A method of cleaning a SiC semiconductor includes the steps of forming an oxide film at the surface of a SiC semiconductor, and removing the oxide film. At the step of forming an oxide film, an oxide film is formed using ozone water having a concentration greater than or equal to 30 ppm. The forming step preferably includes the step of heating at least one of the surface of the SiC semiconductor and the ozone water. Thus, there can be obtained a method of cleaning a SiC semiconductor that can exhibit cleaning effect on the SiC semiconductor.
US08785294B2 Silicon carbide lamina
A method of fabricating an electronic device includes providing a silicon carbide or diamond-like carbon donor body and implanting ions into a first surface of the donor body to define a cleave plane. After implanting, an epitaxial layer is formed on the first surface, and a temporary carrier is coupled to the epitaxial layer. A lamina is cleaved from the donor body at the cleave plane, and the temporary carrier is removed from the lamina. In some embodiments a light emitting diode or a high electron mobility transistor is fabricated from the lamina and epitaxial layer.
US08785288B2 Methods of making memory cells
Some embodiments include a memory cell having a data storage region between a pair of conductive structures. The data storage region is configured to support a transitory structure which alters resistance through the memory cell. The data storage region includes two or more portions, with one of the portions supporting a higher resistance segment of the transitory structure than another of the portions. Some embodiments include a method of forming a memory cell. First oxide and second oxide regions are formed between a pair of conductive structures. The oxide regions are configured to support a transitory structure which alters resistance through the memory cell. The oxide regions are different from one another so that one of the oxide regions supports a higher resistance segment of the transitory structure than the other.
US08785285B2 Semiconductor devices and methods of manufacture thereof
Semiconductor devices and methods of manufacture thereof are disclosed. In one embodiment, a method of manufacturing a semiconductor device includes forming a channel region in a workpiece, and forming a source or drain region proximate the channel region. The source or drain region includes a contact resistance-lowering material layer comprising SiP, SiAs, or a silicide. The source or drain region also includes a channel-stressing material layer comprising SiCP or SiCAs.
US08785284B1 FinFETs and fin isolation structures
FinFETs and fin isolation structures and methods of manufacturing the same are disclosed. The method includes patterning a bulk substrate to form a plurality of fin structures of a first dimension and of a second dimension. The method includes forming oxide material in spaces between the plurality of fin structures of the first dimension and the second dimension. The method includes forming a capping material over sidewalls of selected ones of the fin structures of the first dimension and the second dimension. The method includes recessing the oxide material to expose the bulk substrate on sidewalls below the capping material. The method includes performing an oxidation process to form silicon on insulation fin structures and bulk fin structures with gating. The method further includes forming a gate structure over the SOI fin structures and the bulk fin structures.
US08785282B2 Two step poly etch LDMOS gate formation
A method of making a transistor includes etching a first side of a gate, the gate including an oxide layer formed over a substrate and a conductive material formed over the oxide layer, the etching removing a first portion of the conductive material, implanting an impurity region into the substrate such that the impurity region is self-aligned, and etching a second side of the gate to remove a second portion of the conductive material.
US08785279B2 High voltage field balance metal oxide field effect transistor (FBM)
A semiconductor power device formed in a semiconductor substrate comprising a highly doped region near a top surface of the semiconductor substrate on top of a lightly doped region supported by a heavily doped region. The semiconductor power device further comprises source trenches opened into the highly doped region filled with conductive trench filling material in electrical contact with the source region near the top surface. The semiconductor power device further comprises buried P-regions disposed below the source trenches and doped with dopants of opposite conductivity from the highly doped region. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.
US08785278B2 Nano MOSFET with trench bottom oxide shielded and third dimensional P-body contact
A semiconductor power device may include a lightly doped layer formed on a heavily doped layer. One or more devices are formed in the lightly doped layer. Each device may include a body region, a source region, and one or more gate electrodes formed in corresponding trenches in the lightly doped region. Each of the trenches has a depth in a first dimension, a width in a second dimension and a length in a third dimension. The body region is of opposite conductivity type to the lightly and heavily doped layers. The source region is formed proximate the upper surface. One or more deep contacts are formed at one or more locations along the third dimension proximate one or more of the trenches. The contacts extend in the first direction from the upper surface into the lightly doped layer and are in electrical contact with the source region.
US08785277B2 Method of manufacturing the trench power semiconductor structure
A method of manufacturing a trench power semiconductor structure is provided. The method comprising the steps of: providing a base, forming a dielectric pattern layer on the base to define an active region and a terminal region, wherein a portion of the base in the active region and the terminal region is covered by the dielectric pattern layer; selectively forming a first epitaxial layer on the base without being covered by the dielectric pattern layer; removing the dielectric pattern layer in the active region to form a gate trench on the base, and forming a gate dielectric layer on the first epitaxial layer and on the inner surface of the gate trench; forming the gate structure in the gate trench; utilizing the dielectric pattern layer to forming a body on or in the first epitaxial layer; and forming a source on the upper portion of the body.
US08785273B2 FinFET non-volatile memory and method of fabrication
A method of manufacturing a FinFET non-volatile memory device and a FinFET non-volatile memory device structure. A substrate is provided and a layer of semiconductor material is deposited over the substrate. A hard mask is deposited over the semiconductor material and the structure is patterned to form fins. A charge storage layer is deposited over the structure, including the fins and the portions of it are damaged using an angled ion implantation process. The damaged portions are removed and gate structures are formed on either side of the fin, with only one side having a charge storage layer.
US08785271B2 DRAM cell based on conductive nanochannel plate
A capacitor is formed in nano channels in a conductive body. Embodiments include forming a source contact through a first inter layer dielectric (ILD), forming a conductive body on the first ILD, forming a second ILD on the conductive body, forming drain and gate contacts through the second ILD, conductive body, and first ILD, forming nano channels in the conductive body, forming an insulating layer in the channels, and metalizing the channels. An embodiment includes forming the nano channels by forming a mask on the second ILD, the mask having features with a pitch of 50 nanometers (nm) to 100 nm, etching the second ILD through the mask, etching the conductive body through the mask to a depth of 80% to 90% of the thickness of the conductive body, and removing the mask.
US08785264B2 Organic TFT array substrate and manufacture method thereof
According to an embodiment of the disclosed technology, a manufacture method of an organic thin film transistor array substrate is provided. The method comprises: forming a first pixel electrode, a source electrode, a drain electrode and a data line in a first patterning process; forming an organic semiconductor island and a gate insulating island in a second patterning process; forming a data pad region in a third patterning process; and forming a second pixel electrode, a gate electrode and a gate line in a fourth patterning process.
US08785262B2 Self-aligned carbon nanostructure field effect transistors using selective dielectric deposition
Self-aligned carbon nanostructure field effect transistor structures are provided, which are foamed using selective dielectric deposition techniques. For example, a transistor device includes an insulating substrate and a gate electrode embedded in the insulating substrate. A dielectric deposition-prohibiting layer is formed on a surface of the insulating substrate surrounding the gate electrode. A gate dielectric is selectively formed on the gate electrode. A channel structure (such as a carbon nanostructure) is disposed on the gate dielectric A passivation layer is selectively formed on the gate dielectric. Source and drain contacts are formed on opposing sides of the passivation layer in contact with the channel structure. The dielectric deposition-prohibiting layer prevents deposition of dielectric material on a surface of the insulating layer surrounding the gate electrode when selectively forming the gate dielectric and passivation layer.
US08785261B2 Microelectronic transistor having an epitaxial graphene channel layer
The present disclosure relates to the field of microelectronic transistor fabrication and, more particularly, to forming a graphene layer as a channel layer for a microelectronic transistor.
US08785257B2 Array substrate for display device
Disclosed is array substrate including a pixel region having a switching region, a driving region and a storage region. A switching TFT in the switching region includes a first gate electrode, a first gate insulating layer, a switching active layer on the first gate insulating layer, a switching source electrode on a first switching ohmic contact layer, and a switching drain electrode on a second switching ohmic contact layer; a driving TFT in the driving region is connected to the switching TFT and includes a first gate electrode, a second gate insulating layer, a driving active layer on the second gate insulating layer, a driving source electrode on a first driving ohmic contact layer, and a driving drain electrode on a second driving ohmic contact layer; wherein at least one of the switching and driving TFTs further includes a second gate electrode over the switching or driving active layers.
US08785250B2 Methods and apparatus for flip-chip-on-lead semiconductor package
Fabrication of a semiconductor package includes placing a conductive material on a protrusion from a leadframe to form a first assembly, forming a non-conductive mask about the protrusion, and placing a die on the first assembly, the die having an active area. Fabrication can further include reflowing the conductive material to form a second assembly such that a connection extends from the die active area, through the conductive material, to the protrusion. A semiconductor package includes a leadframe having a protrusion, a conductive material reflowed to the protrusion, and a die having an active area coupled to the protrusion by the reflowed solder.
US08785248B2 Wafer level packaging using a lead-frame
Wafer level packaging using a lead-frame. When used to package two or more chips, a final product having QFN package-like finish. The final product will also have a performance rivaling or exceeding that of a corresponding monolithic chip because of the very close connection of the two or more chips and the ability to tailor the fabrication processing of each chip to only that required for the devices on that chip. The wafer level packaging can also be used to package monolithic chips, as well as chips having active devices on one chip and passive devices on a second chip. Various exemplary embodiments are disclosed.
US08785247B2 Chip package and method for forming the same
According to an embodiment, a chip package is provided, which includes: a substrate having a first surface and a second surface; a device region formed in the substrate; a passivation layer formed overlying the first surface of the substrate; at least a polymer planarization layer formed overlying the passivation layer; a package substrate disposed overlying the first surface of the substrate; and a spacer layer disposed between the package substrate and the passivation layer, wherein the spacer layer and the package substrate surround a cavity overlying the substrate, wherein the polymer planar layer does not extends to an outer edge of the spacer layer.
US08785246B2 Multiple seal-ring structure for the design, fabrication, and packaging of integrated circuits
A semiconductor circuit design includes an outer seal-ring and an inner seal-ring for each sub-section of the design that may potentially be cut into separate die. The use of multiple seal-rings permits a single circuit design and fabrication run to be used to support flexibly packaging different product releases having different numbers of integrated circuit blocks per packaged unit.
US08785237B2 Method of forming variable resistance memory device
A method of forming a variable resistance memory device includes forming an opening in an insulating layer, and forming a variable resistance layer by filling the opening with an antimony rich antimony-tellurium compound.
US08785236B2 Solar cell contact formation using laser ablation
The formation of solar cell contacts using a laser is described. A method of fabricating a back-contact solar cell includes forming a poly-crystalline material layer above a single-crystalline substrate. The method also includes forming a dielectric material stack above the poly-crystalline material layer. The method also includes forming, by laser ablation, a plurality of contacts holes in the dielectric material stack, each of the contact holes exposing a portion of the poly-crystalline materiat layer; and forming conductive contacts in the plurality of contact holes.
US08785235B2 Apparatus and method for producing solar cells
A method and apparatus for forming a solar cell. The apparatus includes a housing defining a vacuum chamber and a rotatable substrate apparatus configured to hold a plurality of substrates on a plurality of surfaces wherein each of the plurality of surfaces are disposed facing an interior surface of the vacuum chamber. A first sputtering source is configured to deposit a plurality of absorber layer atoms of a first type over at least a portion of a surface of each one of the plurality of substrates. An evaporation source is disposed in a first subchamber of the vacuum chamber and configured to deposit a plurality of absorber layer atoms of a second type over at least a portion of the surface of each one of the plurality of substrates. A first isolation source is configured to isolate the evaporation source from the first sputtering source.
US08785231B2 Method of making semiconductor device
A semiconductor device includes a sensor portion, a cap portion, and an ion-implanted layer. The sensor portion has a sensor structure at a surface portion of a surface. The cap portion has first and second surfaces opposite to each other and includes a through electrode. The surface of the sensor portion is joined to the first surface of the cap portion such that the sensor structure is sealed between the sensor portion and the cap portion. The ion-implanted layer is located on the second surface of the cap portion. The through electrode extends from the first surface to the second surface and is exposed through the ion-implanted layer.
US08785230B2 Localized surface plasmon resonance sensor using chalcogenide materials and method for manufacturing the same
A localized surface plasmon resonance sensor may include a localized surface plasmon excitation layer including a chalcogenide material. The chalcogenide material may include: a first material including at least one of selenium (Se) and tellurium (Te); and a second material including at least one of germanium (Ge) and antimony (Sb). The localized surface plasmon excitation layer may be prepared by forming a thin film including the chalcogenide material and crystallizing the thin film to have a predetermined pattern by irradiating laser on the thin film.
US08785225B2 Thin-film transistor pixel structure having shielding layer and manufacturing method thereof
A thin-film transistor (TFT) pixel structure and manufacturing method thereof are described. The TFT pixel structure includes a substrate, first conducting layer, gate insulation layer, channel layer, second conducting layer, contact holes, passivation layer and transparent conducting layer. The method includes: forming gate insulation layer on substrate and covering scan lines, gate electrode layer and shielding layer; forming the second conducting layer on substrate; and patterning the second conducting layer for generating data lines, drain layer, and source layer on channel layer to construct thin-film transistors, channel layer being disposed between the shielding layer and source layer, wherein when light beam illuminates on substrate, the shielding layer is correspondingly disposed to channel layer along an emitting direction of the light beam for shielding channel layer from light beam by the shielding layer to solve the problems of abnormal display quality and image sticking and maintain aperture rate.
US08785219B1 Optoelectronic semiconductor device and the manufacturing method thereof
The present application provides a method of manufacturing an optoelectronic semiconductor device, comprising the steps of: providing a substrate; forming an optoelectronic system on the substrate; forming a barrier layer on the optoelectronic system; forming an electrode on the barrier layer; and annealing the optoelectronic semiconductor device; wherein the optoelectronic semiconductor device has a first forward voltage before the annealing step and has a second forward voltage after the annealing step, and a difference between the second forward voltage and the first forward voltage is smaller than 0.2 Volt.
US08785217B2 Tunable radiation source
An energy distribution of soft error-inducing radiation likely to be encountered by an electronic circuit during operation is determined. A tuned radiation source having a source energy distribution similar to the determined energy distribution is prepared. The electronic circuit is tested using the tuned radiation source.
US08785216B2 Substrate processing apparatus, substrate processing method, and program for implementing the method
A substrate processing method which is capable of enhancing productivity in manufacturing product substrates. In process chambers of an etching apparatus, etching is carried out on a substrate as an object to be processed, and dummy processing is carried out on at least one non-product substrate before execution of the etching. A host computer determines whether or not the dummy processing is to be executed. The host computer determines whether or not the interior of each of the process chambers and is in a stable state, and omits the execution of the dummy processing when it is determined that it is in the stable state.
US08785215B2 Method for repairing damage of dielectric film by cyclic processes
A method for repairing process-related damage of a dielectric film includes: (i) adsorbing a first gas containing silicon on a surface of the damaged dielectric film without depositing a film in the absence of reactive species, (ii) adsorbing a second gas containing silicon on a surface of the dielectric film, followed by applying reactive species to the surface of the dielectric film, to form a monolayer film thereon, and (iii) repeating step (ii). The duration of exposing the surface to the first gas in step (i) is longer than the duration of exposing the surface to the second gas in step (ii).
US08785213B2 Method of fabricating non-volatile memory device having small contact and related devices
A sacrificial pattern is formed to partially cover the pipe-shaped electrode. A sacrificial spacer is formed on a lateral surface of the sacrificial pattern. The sacrificial spacer extends across the pipe-shaped electrode. The sacrificial spacer has a first side and a second side opposite the first side. The sacrificial pattern is removed to expose the pipe-shaped electrode proximal to the first and second sides of the sacrificial spacer. The pipe-shaped electrode exposed on both sides of the sacrificial spacer may be primarily trimmed. The pipe-shaped electrode is retained under the sacrificial spacer to form a first portion, and a second portion facing the first portion. The second portion of the pipe-shaped electrode is secondarily trimmed. The sacrificial spacer is removed to expose the first portion of the pipe-shaped electrode. A data storage plug is formed on the first portion of the pipe-shaped electrode.
US08785212B2 Oligosaccharide modification and labeling of proteins
The present invention generally relates to methods of functionalizing proteins, particularly antibodies, at oligosaccharide linkages, methods of humanizing antibodies by modifying glycosylation, as well as to novel antibodies linked to modified oligosaccharides. The invention further relates to kits that may be used to produce the antibodies of the invention.
US08785211B2 Methods using pores
The invention relates to a method of identifying an individual nucleotide, comprising (a) contacting the nucleotide with a transmembrane protein pore so that the nucleotide interacts with the pore and (b) measuring the current passing through the pore during the interaction and thereby determining the identity of the nucleotide. The invention also relates to a method of sequencing nucleic acid sequences and kits related thereto.
US08785208B2 Fluorescent metal ion indicators with large stokes shifts
The present invention provides fluorogenic compounds for the detection of target metal ions wherein the compounds exhibit a Stokes shift greater than 50 nm and the detectable signal is modulated by photoinduced electron transfer (PET). The present compounds consist of three functional elements, the ion sensing moiety (chelating moiety), the reporter moiety (fluorophore or fluorescent protein) and spacer or linker between the sensing and reporter moieties of the present compound that allows for PET upon binding of a metal ion and excitation by an appropriate wavelength.
US08785207B2 Method and apparatus for measuring multiple parameters in-situ of a sample collected from environmental systems
The present invention relates generally a method and apparatus for measuring multiple parameters in-situ in a sample collected from an environmental system via a single device. In one embodiment, the method includes collecting the sample from said environmental system via the single device, measuring a first parameter of the sample in-situ via the single device, adding a reagent tot the sample within the single device to create a reagent infused sample and measuring a second parameter of the sample in-situ via the single device using the reagent infused sample.
US08785204B2 Methods of assaying for tetrahydrocannabinol
The invention provides a method of assaying for tetrahydrocannabinol in a body fluid. The method includes contacting a sample of body fluid with an imine capable of reacting with tetrahydrocannabinol to yield a quinone imine, and detecting the formation of a quinone imine, where the sample is contacted with the reagent compound at a pH of at least 10.5.
US08785200B2 Transfection reagents
Disclosed are cationic lipid compounds and compositions of lipid aggregates for delivery of macromolecules and other compounds into cells. The compounds can be used alone or in combination with other compounds to prepare liposomes and other lipid aggregates suitable for transfection or delivery of compounds to target cells, either in vitro or in vivo. The compounds are preferably polycationic and preferably form highly stable complexes with various anionic macromolecules, particularly polyanions such as nucleic acids. These compounds have the property, when dispersed in water, of forming lipid aggregates which associate strongly, via their cationic portion, with polyanions. Also disclosed are intermediates for preparing the compound and compositions of the invention and methods of using the compounds to introduce other compounds into cells.
US08785196B2 Methods for modulating osteochondral development using bioelectrical stimulation
Compositions and methods are provided for modulating the growth, development and repair of bone, cartilage or other connective tissue. Devices and stimulus waveforms are provided to differentially modulate the behavior of osteoblasts, chondrocytes and other connective tissue cells to promote proliferation, differentiation, matrix formation or mineralization for in vitro or in vivo applications. Continuous-mode and pulse-burst-mode stimulation of cells with charge-balanced signals may be used. Bone, cartilage and other connective tissue growth is stimulated in part by nitric oxide release through electrical stimulation and may be modulated through co-administration of NO donors and NO synthase inhibitors. Bone, cartilage and other connective tissue growth is stimulated in part by release of BMP-2 and BMP-7 in response to electrical stimulation to promote differentiation of cells. The methods and devices described are useful in promoting repair of bone fractures, cartilage and connective tissue repair as well as for engineering tissue for transplantation.
US08785195B2 Covered micro gel fiber
A microfiber showing improved mechanical strength, which comprises a micro gel fiber consisting of collagen gel or the like covered with high strength hydrogel such as alginate gel.
US08785192B2 Endothelial cell production by programming
The invention generally regards methods for providing endothelial cells and precursors of endothelial cells from a variety of cell sources, such as pluripotent stem cells. Also provided are therapeutic compositions including the provided endothelial cells, and methods of using them for the treatment of subjects.
US08785191B2 Concentration of stem cells obtained during orthopaedic surgeries
Methods for isolating and concentrating bone marrow stromal cells drawn from various surgical sites (for example, the proximal humeral head during rotator cuff repair, or the distal femur during ACL surgery) during arthroscopic or open orthopaedic surgery. The pluripotent cells obtained from the bone marrow aspirate can then be reimplanted during the same surgery to improve healing.
US08785186B2 Hybrid cells for treating cancer patients
The present invention relates to cancer treatment compositions and methods for treating a specific cancer patient population. In particular, the application describes methods of treating a patient with cancer, such as a neuroblastoma, with a hybrid cell preparation.
US08785185B2 Differentiation of human embryonic stem cells
The present invention provides methods to promote the differentiation of pluripotent stem cells into cells expressing markers characteristic of the pancreatic endocrine lineage that co-express PDX1, NKX6.1, but do not express CDX2 and NGN3.
US08785183B2 Active plastic material in oil
A method is provided of prolonging the shelf life of probiotic lactic-acid producing bacteria formulated in oil, by using a specific moisture absorbing technology.
US08785178B2 Perifusion device
A perifusion device includes at least one sample container for cells, the sample container having an inlet and an outlet. The container receives test liquid through the inlet and discharges the liquid through the outlet. A receptacle housing has a plurality of receptacles for receiving fluid from the outlet of the sample container. A drive is connected to the receptacle housing for moving the receptacle housing such that liquid samples are collected sequentially from the outlet of the sample containers. A computer can be provided to control movement of the receptacle housing at predetermined times, and to record data identifying liquid samples in the receptacles. The test liquid includes at least one stimuli for the cells, which can be the presence, absence, or concentration of a compound in the liquid, or a physical property of the liquid such as temperature. The liquid collected in the receptacles is analyzed to determine the response of the cells to the stimuli.
US08785177B2 Methods for nano-mechanoporation
Methods for creating a transient nanoscale opening in a cell membrane and methods for transporting a desired species through the nanoscale opening are provided. A nano-sized needle-like tip can be used to mechanically slice the cell membrane to create a transient, localized nanoscale slit. The nanoscale slit may be used for transferring exogenous molecules into a living cell.
US08785176B2 Post protein hydrolysis removal of a potent ribonuclease inhibitor and the enzymatic capture of DNA
The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample.
US08785172B2 Savinase variants having an improved wash performance on egg stains
Subtilase variants having an improved wash performance on egg stains. These subtilases are useful exhibiting excellent or improved wash performance on egg stains when used in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions.
US08785169B2 Cutinase-producing genetically engineered microorganism and use thereof
The present invention relates to the field of bioengineering and discloses a cutinase-producing genetically engineered microorganism and use thereof. Recombinant plasmid Tfu_0883-hlyAs/pET20b(+) was constructed and transformed into E. coli BL21(DE3) to obtain recombinant E. coli strain Tfu_0883-hlyAs/pET20b(+)/E. coli BL21(DE3). Specific growth rate was maintained at a certain value using fed-batch fermentation mode. After fermenting 30-34 hours, the enzyme activity in the supernatant reached 700-750 U/mL. The present invention uses glycerol as the main raw material and employs semi-synthetic medium, has the advantages of good stability and ease of control, and is suitable for large-scale production.
US08785166B2 Increased production of isobutanol in yeast with reduced mitochondrial amino acid biosynthesis
Yeast cells with reduced activity of certain enzymes involved in branched chain amino acid biosynthesis in yeast mitochondria are described. Target enzymes include threonine deaminase, isopropylmalate synthase, and optionally branched chain amino acid transaminase.
US08785161B2 Method for producing L-amino acids using bacteria of the enterobacteriaceae family
There is disclosed a method for producing L-amino acid, for example L-threonine, L-lysine, L-histidine, L-phenylalanine, L-arginine or L-glutamic acid, using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified to enhance an activity of D-xylose permease.
US08785159B2 Extracellular secretion of recombinant proteins
Nucleic acids encoding secretion signals, expression vectors containing the nucleic acids, and host cells containing the expression vectors are disclosed. Also disclosed are polypeptides that contain the secretion signals and methods of producing polypeptides, including methods of directing the extracellular secretion of the polypeptides. Exemplary embodiments include cellulase proteins fused to secretion signals, methods to produce and isolate these polypeptides, and methods to degrade lignocellulosic biomass.
US08785155B2 Process for obtaining biochemicals in a zero-liquid discharge plant
A method is presented for the production of cellulosic ethanol, acetic acid and derivatives from the extract containing fibers and hemicelluloses after steam cooking of biomass in a host plant. The process is integrated with the host plant process to minimize the effect of loss of heat value from the extracted hemicelluloses and eliminate the need for the waste water treatment plant.
US08785152B2 Process for production of non-natural protein having ester bond therein
A non-natural protein having at least one ester bond in its polypeptide main chain is synthesized by using an in vivo translation system in a ribosome. The following components (a) to (c) are expressed in a cell or an cell extraction solution in the presence of an α-hydroxy acid: (a) an aminoacyl-tRNA synthetase which can activate the α-hydroxy acid; (b) suppressor tRNA which can bind to the α-hydroxy acid in the presence of the aminoacyl-tRNA synthetase; and (c) a gene encoding a desired protein having a nonsense mutation or a frame-shift mutation at a desired site.
US08785151B2 Biosynthetically generated pyrroline-carboxy-lysine and site specific protein modifications via chemical derivatization of pyrroline-carboxy-lysine and pyrrolysine residues
Disclosed herein is pyrroline-carboxy-lysine (PCL), a pyrrolysine analogue, which is a natural, biosynthetically generated amino acid, and methods for biosynthetically generating PCL. Also disclosed herein are proteins, polypeptides and peptides that have PCL incorporated therein and methods for incorporating PCL into such proteins, polypeptides and peptides. Also disclosed herein is the site-specific derivatization of proteins, polypeptides and peptides having PCL or pyrrolysine incorporated therein. Also disclosed herein is the crosslinking of proteins, polypeptides and peptides having PCL or pyrrolysine incorporated therein.
US08785149B2 In vitro cellular bioassay for neurotoxicity testing
The present invention provides neurotoxicity and developmental neurotoxicity screening methods employing primary cultured neurons from Drosophila.
US08785148B2 Method and device for rapid detection of bacterial antibiotic resistance/susceptibility
Described herein is a method and a device for expediting delivery of an agent to a damaged bacterial cell. In one embodiment, the methods and devices are useful for screening candidate antibiotics. In another embodiment, the methods and devices described herein are used to determine susceptibility of bacteria to an antibiotic. The methods also provide a method for determining an appropriate antibiotic to treat an individual having a bacterial infection.
US08785137B2 Method for renal disease diagnosis using Rab23 as marker
Use of Annexin A1 or Rab23 as a biomarker for diagnosing kidney disease or assessing efficacy of kidney disease treatment.
US08785135B2 Mutant G-protein coupled receptors and methods for selecting them
The present invention relates in some aspects to mutant G protein coupled receptors (GPCRs) and methods for selecting those with increased stability. In certain aspects, the invention relates to the selection and preparation of mutant GPCRs which have increased stability under a particular condition compared to their respective parent proteins.
US08785132B2 Aptamer sandwich assays
The present invention provides methods for identifying the plurality of aptamers that bind to different sites of a target molecule and methods for using the same, for example, in sandwich assays. In particular, the plurality of aptamers binding to different sites of the target molecules is identified from a library of aptamers identified from the same SELEX process.
US08785129B2 Method and probe set for detecting cancer
Methods for detecting cancer that include hybridizing a set of chromosomal probes to a biological sample obtained from a patient, and identifying if aneusomic cells are present in a selected subset of cells obtained from the biological sample are described. A set of chromosomal probes and kits for detecting cancer that include sets of chromosomal probes, are also described.
US08785125B2 Compositions, reaction mixtures and methods for detecting nucleic acids from type A1 and/or type C1 human papillomavirus
Nucleic acid oligonucleotide sequences are disclosed which include amplification oligomers and probe oligomers which are useful for detecting multiple types of human papillomaviruses (HPV) associated with cervical cancer. Methods for detecting multiple HPV types in biological specimens by amplifying HPV nucleic acid sequences in vitro and detecting the amplified products are disclosed.
US08785121B2 Single-stranded nucleic acid molecule for controlling gene expression
Provided is a novel nucleic acid molecule that is a single-stranded nucleic acid molecule including an expression inhibitory sequence that inhibits expression of a target gene. The single-stranded nucleic acid molecule includes, in sequence from the 5′ side to the 3′ side: a 5′ side region (Xc); an inner region (Z); and a 3′ side region (Yc). The inner region (Z) is composed of an inner 5′ side region (X) and an inner 3′ side region (Y) that are linked to each other. The 5′ side region (Xc) is complementary to the inner 5′ side region (X). The 3′ side region (Yc) is complementary to the inner 3′ side region (Y). At least one of the inner region (Z), the 5′ side region (Xc), and the 3′ side region (Yc) includes the expression inhibitory sequence.
US08785116B2 Methods for evaluating the suitability of an organ for transplant
Methods of determining the health of an organ, such as a transplant organ, by measuring the ex-situ oxygen consumption rate of the organ. Systems for preserving and transporting organs while monitoring viability by measuring oxygen consumption rates.
US08785114B2 Method for manufacturing micro-structure
A micro-structure is manufactured by patterning a sacrificial film, forming an inorganic material film on the pattern, providing the inorganic material film with an aperture, and etching away the sacrificial film pattern through the aperture to define a space having the contour of the pattern. The patterning stage includes the steps of (A) forming a sacrificial film using a composition comprising a cresol novolac resin and a crosslinker, (B) exposing patternwise the film to first high-energy radiation, (C) developing, and (D) exposing the sacrificial film pattern to second high-energy radiation and heat treating for thereby forming crosslinks within the cresol novolac resin.
US08785113B2 Method and materials for reverse patterning
A silsesquioxane resin is applied on top of the patterned photo-resist and cured to produce a cured silsesquioxane resin on top of the pattern surface. Subsequently, a reactive ion etch recipe containing CF4 to “etch back” the silicon resin to the top of the photoresist material, exposing the entire top surface of the organic based photoresist. Then, a second reactive ion etch recipe containing O2 to etch away the organic photoresist. The result is a silicon resin film with via holes with the size and shape of the post that were patterned into the photoresist. Optionally, the new pattern can be transferred into the underlying layer(s).
US08785111B2 Hydrophilic nanoporous materials
The present application discloses a method for preparing and rendering hydrophilic a nanoporous material of a polymer matrix which has a porosity of 0.1-90% (v/v), such that the ratio between the final water absorption (% (w/w)) and the porosity (% (v/v)) is at least 0.05, the method comprising the steps of: (a) preparing a precursor material comprising at least one polymeric component and having a first phase and a second phase; (b) removal of at least a part of the first phase of the precursor material prepared in step (a) so as to leave behind a nanoporous material of the polymer matrix; (c) irradiating at least a part of said nanoporous material with light of a wave length of in the range of 250-400 nm (or 200-700 nm) in the presence of oxygen and/or ozone. Corresponding hydrophilic nanoporous materials are also disclosed.
US08785101B2 Toner
Provided is a toner containing toner particles, each of which includes a binder resin containing a polyester as a main component, a colorant, and a wax, in which the binder resin includes a block polymer in which a segment capable of forming a crystalline structure and a segment incapable of forming a crystalline structure are bonded, the toner has a maximum endothermic peak from the binder resin, as determined by differential scanning calorimetry measurement, with a peak temperature in a specific range and with an endothermic quantity in a specific range, and the wax is an ester wax having a functionality of 3 or more.
US08785098B2 Transparent toner for electrostatic latent image development, method for producing the same, electrostatic latent image developer, toner cartridge, process cartridge, and image forming apparatus
The invention provides a transparent toner for electrostatic latent image development, containing a polyester resin and a release agent, the difference between an endothermic peak Tm of the release agent in a temperature increasing process and an exothermic peak Tc of the release agent in a temperature decreasing process when measured by an ASTM method with a differential scanning calorimeter (DSC) is from about 40° C. to about 50° C., and the degree of exposure of the release agent at the surface of the toner as determined quantitatively by X-ray photoelectron spectroscopy (XPS) is about 10% or less.
US08785092B2 Toner additives
The disclosure relates generally to toner additives, and in particular, toner additives that provide desired higher toner charge and low relative humidity (RH) sensitivity. The toner additives comprise titania nanotubes or titania nanosheets in combination with or in place of the commonly used anatase or rutile crystalline titania.
US08785088B2 Colored composition, colored cured film, color filter, method for producing color filter, liquid crystal display device, solid-state imaging device, and novel dipyrromethene metal complex compound or tautomer thereof
Provided is a colored composition including at least one selected from the group consisting of a compound represented by the following formula (I) and a tautomer thereof: wherein in formula (I), R2 to R5 each independently represent a hydrogen atom or a monovalent substituent; R7 represents a hydrogen atom, a halogen atom, an alkyl group, an aryl group or a heterocyclic group; Ma represents a metal or a metal compound; X3 and X4 each independently represent NR, a nitrogen atom, an oxygen atom, or a sulfur atom, wherein R represents a hydrogen atom, an alkyl group, an alkenyl group, an aryl group, a heterocyclic group, an acyl group, an alkylsulfonyl group, or an arylsulfonyl group; X5 represents a group required to neutralize the charge of Ma; a represents 1 or 2; and R8 to R17 each independently represent a hydrogen atom or a monovalent substituent, provided that at least one of R8 to R17 represents a particular polymerizable substituent.
US08785087B2 Pigment-dispersed composition, curable composition, color filter and production method thereof
The present invention provides a pigment-dispersed composition including at least a polymer compound (A-1) having at least one selected from the structural units represented by the following formulae (1) to (3), a pigment (B) and a solvent (C), and a pigment-dispersed composition including at least a resin (D) having an acid number of 100 mg KOH/g or more, a dispersion resin (A-2) having an acid number of less than 100 mg KOH/g and an unsaturation equivalent of less than 600, a pigment (B), and a solvent (C) [R1 to R20: a hydrogen atom, a monovalent organic group; A1 to A3: an oxygen atom, a sulfur atom, —N(R21)—; G1 to G3: a divalent organic group; X, Z: an oxygen atom, a sulfur atom, —N(R22)—; Y: an oxygen atom, a sulfur atom, a phenylene group, —N(R23)—; and R21 to R23: an alkyl group].
US08785086B2 Reflective mask blank, method of manufacturing the same, and reflective mask
To solve a problem of reduction in accumulated energy due to backward scattering, leading to degradation in CD linearity, which is caused when a generally used high-contrast resist is used in the manufacture of a reflective mask. A reflective mask blank for manufacturing a reflective mask includes a substrate, a multilayer reflective film which is formed on the substrate and adapted to reflect exposure light, and an absorber film which is formed on the multilayer reflective film and adapted to absorb the exposure light. A resist film for electron beam writing is formed on the absorber film and the contrast value γ of the resist film for electron beam writing is 30 or less.
US08785079B1 Metal-foam electrodes for batteries and fuel cells
This invention provides metal-foam electrodes for batteries and fuel cells. In some variations, an electrode includes a first metal layer disposed on a second metal layer, wherein the first metal layer comprises an electrically conductive, open-cell metal foam with an average cell diameter of about 25 μm or less. The structure also includes smaller pores between the cells. The electrode forms a one piece monolithic structure and allows thicker electrodes than are possible with current electrode-fabrication techniques. These electrodes are formed from an all-fluidic plating solution. The disclosed structures increase energy density in batteries and power density in fuel cells.
US08785078B2 Fuel cell
The present invention provides a fuel cell which is capable of improving electric power generation efficiency at a time of high-temperature operation. The fuel cell 10 comprising: a membrane electrode assembly 4; and a pair of gas separators 7, 8 sandwiching the membrane electrode assembly 4 therebetween, wherein at least one of the gas separator(s) 7 and/or 8 comprises a compact layer(s) 7c and/or 8c which is capable of preventing permeation of fluid and a porous layer (s) 7d and/or 8d which allows permeation of fluid, and the porous layer(s) 7d and/or 8d is impregnated with a water-soluble liquid having higher boiling point than that of water.
US08785076B2 Portable fuel cell systems and methods therefor
A fuel cell system including, among other things, one or more of a fuel cell, a fuel reservoir, a current collecting circuit, a plenum, or a system cover. The fuel reservoir is configured to store fuel, and may include a regulator for controlling an output fuel pressure and a refueling port. A surface of the fuel reservoir may be positioned adjacent a first fuel cell portion. The current collecting circuit is configured to receive and distribute fuel cell power and may be positioned adjacent a second fuel cell portion. The plenum may be formed when the fuel reservoir and the first fuel cell portion are coupled or by one or more flexible fuel cell walls. The system cover allows air into the system and when combined when a fuel pressure in the plenum, may urge contact between the fuel cell and the current collecting circuit.
US08785074B2 Fuel cell stack compression devices and methods
A ceramic baffle is configured to place a load on a stack of electrochemical cells and direct a reactant feed flow stream to the stack.
US08785070B2 Direct oxidation fuel cells with improved cathode gas diffusion media for low air stoichiometry operation
A cathode for use in a direct oxidation fuel cell (DOFC) comprises a gas diffusion medium (GDM) including a backing layer and a microporous layer comprising a fluoropolymer and an electrically conductive material, wherein loading of the fluoropolymer in the microporous layer is in the range from about 10 to about 60 wt. %. In use, a concentrated solution of a liquid fuel is supplied to an anode and an oxidant to the cathode of the fuel cell, and the fuel cell may be operated at a low oxidant stoichiometry ξc not greater than about 2.5.
US08785065B2 Catalyst for generating hydrogen and method for generating hydrogen
The present invention provides a catalyst for generating hydrogen, containing a composite metal of iron and nickel, the catalyst used in a decomposition reaction of at least one compound selected from the group consisting of hydrazine and hydrates thereof; and a method for generating hydrogen, including contacting the catalyst for generating hydrogen with at least one compound selected from the group consisting of hydrazine and hydrates thereof. According to the invention, hydrogen can be efficiently generated with improved selectivity in the method for generating hydrogen that utilizes the decomposition reaction of hydrogen.
US08785061B2 CO conversion catalyst for use in fuel cell in DSS operation, method for producing the same, and fuel cell system
To provide a CO conversion catalyst for use in a fuel cell in a DSS operation, which includes a Cu—Al-Ox catalyst, in which the Cu—Al-Ox catalyst has a boehmite phase formed in at least a part of the Cu—Al-Ox catalyst. The CO conversion catalyst has an improved degree of dispersion of Cu metal by the boehmite phase formed therein, and hence can be prevented from sintering of copper caused due to steam, thereby achieving improved durability with respect to the function as the CO conversion catalyst.
US08785059B2 Power generation
A method and apparatus are disclosed for generating electrical power during negative pressure therapy. The apparatus includes a fuel cell, comprising an anode element and a cathode element, arranged to collect biological fluid from a wound site to which a negative pressure is applied and electro-oxidize a component of the biological fluid at the anode element and/or electro-reduce a component of the biological fluid at the cathode element.
US08785058B2 Integrated biofuel cell with aligned nanotube electrodes and method of use thereof
The present disclosure provides for a method of forming, producing or manufacturing functionalized and soluble nanomaterials, most specifically carbon nanotubes on a substrate, which can be used in the production or manufacture of biofuel cells. One embodiment provides for the coupling of biofuel cells with a nanomaterial, wherein the nanomaterial supports catalytic enzymes. Another embodiment provides for a biofuel cell which uses enzymes immobilized on nanomaterials as electrodes. Another embodiment provides for the construction of a biofuel cell, wherein the application of a microwave process, and/or an electrochemical technique, is used to develop a biofuel cell having nanomaterial/enzyme-based electrodes on a substrate. Another embodiment provides for a composite of nanomaterial grown on a substrate, coupled to tethered or bonded enzymes, which makes it possible to fabricate direct electron transfer electrodes. A method for producing a nanomaterial-substrate system is also disclosed.
US08785051B2 Nonaqueous-electrolyte battery and method for producing the same
Provided are a nonaqueous-electrolyte battery in which short circuits between the positive- and negative-electrode layers can be suppressed with certainty and a method for producing the battery. A nonaqueous-electrolyte battery 100 includes a positive-electrode active-material layer 12 containing a Li-containing oxide; a negative-electrode active-material layer 22 on which deposition of Li metal can occur; and a sulfide-solid-electrolyte layer (SE layer) 3 disposed between these active-material layers 12 and 22. The SE layer 3 of the nonaqueous-electrolyte battery 100 includes a powder-formed layer 31 and a dense-film layer 32 formed on a surface of the powder-formed layer 31 by a vapor-phase process. In the nonaqueous-electrolyte battery 100, the powder-formed layer 31 is formed by a compression-molding process on a positive-electrode body including the positive-electrode active-material layer 12 and the dense-film layer 32 is then formed by a vapor-phase process on the positive-electrode body that is provided with the powder-formed layer 31 and serves as a substrate.
US08785050B2 Lithium ion secondary battery
Provided is a lithium-ion secondary battery having an excellent initial capacity as well as a good capacity retention rate. The battery comprises a positive electrode comprising a positive electrode active material, a negative electrode comprising a negative electrode active material, and a non-aqueous liquid electrolyte. The negative electrode active material comprises a graphitic material that satisfies each of the following properties: (a) in its Raman spectrum obtained by Raman scattering analysis using an exciting light at a wavelength of 532 nm, having a ratio of its D-peak intensity ID to its G-peak intensity IG, an R value (ID/IG), of 0.15 or smaller; and (b) having a full width at half maximum of the G peak, ΔvG, of 23 cm−1 or smaller. The secondary battery has a capacity retention rate of 70% or greater when subjected to 500 cycles of charging and discharging at a constant current rate of 2 C at 60° C.
US08785045B2 Active material, electrode, battery, and method of manufacturing active material
An active material comprises a core particle containing LiCo(1-x)MxO2 and/or Li(Mn(1-y)My)2O4, and a coating part covering at least part of a surface of the core particle, while the coating part contains LiVOPO4. Here, M is at least one element selected from the group consisting of Al, Mg, and transition elements, 0.95≧x≧0, 0.2≧y≧0, and V in LiVOPO4 may partly be substituted by at least one element selected from the group consisting of Ti, Ni, Co, Mn, Fe, Zr, Cu, Zn, and Yb.
US08785041B2 Electrode and production method thereof
An electrode includes a collector formed with a conductive resin layer and an active material layer formed on the conductive resin layer. The active material layer comprises an active material and a binder polymer, and the conductive resin layer is bonded by thermal fusion bonding to the active material layer.
US08785040B2 Positive electrode for rechargeable lithium battery, method for manufacturing the same, and rechargeable lithium battery including the same
A positive electrode for a rechargeable lithium battery including a net-type current collector and a positive active material layer formed on both sides of the current collector and also including a positive active material and a binder and having a thickness of about 150 μm or more, a method of manufacturing the same, and a rechargeable lithium battery including the same.
US08785038B2 Negative electrode active material
A negative electrode active material and a secondary battery are provided. The negative electrode active material can be useful in maintaining excellent cell efficiency and lifespan while showing high-capacity properties, and the secondary battery may be manufactured using the negative electrode active material.
US08785033B2 Assembled battery
In an assembled battery including at least two unit cells provided within a supporter, each unit cell is a thin laminate cell packaged with a laminate, and each unit cell is covered by at least one resin. Thus, the assembled battery has a stable performance without structure breakdown or a fracture of the connection tab even when vibration is applied.
US08785031B2 Polymer electrolyte fuel cell separator made of pure titanium or titanium alloy and method of production of same
The present invention provides a polymer electrolyte fuel cell separator made of pure titanium or a titanium alloy superior in contact resistance with carbon paper and a method of production of the same, that is, a separator having a surface layer part to which conductive compound particles are affixed, characterized in that the surface oxide has a thickness of 3 to 15 nm in range, an average carbon concentration in a range from an outermost surface, including the oxide layer, to a depth of 100 nm is 0.02 to 6 at %, and the conductive compound particles have an average particle size of 0.01 to 20 μm. Further, the method of production of the present invention is characterized by forming, blast treating a surface of the formed article by particles comprised of conductive compound particles of an average particle size of 0.01 to 20 μm covering a surface of superhard core particles, impregnating it by a nitric acid aqueous solution of a concentration of 15 to 71 mass % and a temperature of 40 to 100° C. for 30 seconds to 180 minutes by spraying or dipping, then washing it.
US08785030B2 Flexible battery and method for producing the same
Disclosed is a flexible battery including a sheet-like electrode group, an electrolyte, and a housing with flexibility enclosing the electrode group and electrolyte. The housing includes a film material folded into two in which the electrode group is inserted. The film material has two facing portions respectively facing two principal surfaces of the electrode group, a fold line which is between the two facing portions and along which the film material is folded, and two bonding margins respectively set around the two facing portions. The two bonding margins are bonded to each other into a bonded portion. At least the two facing portions of the film material are formed in a corrugated shape having a plurality of ridge and valley lines arranged in parallel to each other. The ridge lines in one of the two facing portions are overlapped with the valley lines in the other. The fold line is parallel to the ridge and valley lines.
US08785029B2 Connection plate for battery terminals and method for manufacturing connection plate for battery terminals
A connection plate for battery terminals capable of inhibiting a base and a battery terminal connection portion from being detached from each other is provided. This connection plate for battery terminals (2) includes a battery terminal connection portion (4) fitted into a second hole (31) of a base (3) made of first metal, including a hole for connection (42) into which a second battery terminal (1b) is inserted and a flange portion (4b), while the battery terminal connection portion is constituted by at least a first layer (40) made of second metal, arranged on a side opposite to the base and a second layer (41) made of third metal, arranged between the base and the first layer.
US08785025B2 Air-cooled battery pack
A battery pack includes first and second battery cells, a first duct, the first duct having an inlet at a first end and an inclined surface at a second end opposite the first end, and a main body, the main body being connected to the first duct and encompassing the first and second battery cells. The inclined surface may have a first edge and a second edge opposite the first edge, the first edge being adjacent to the battery cells, the inclined surface being inclined such that the second edge is closer to the inlet than the first edge is, and a gap may be between the first and second battery cells, the gap providing a passage for a heat transfer medium to flow from the first duct between the first and second battery cells.
US08785024B2 Combination of heat pipe and louvered fins for air-cooling of Li-Ion battery cell and pack
A heat pipe is described. The heat pipe includes a heat pipe body containing a working fluid; and a louvered cooling fin adjacent to one end of the heat pipe body, the louvered cooling fin extending outward from a surface of the heat pipe body. Air-cooled battery packs containing the heat pipe are also described.
US08785023B2 Cascade redox flow battery systems
A reduction/oxidation (“redox”) flow battery system includes a series of electrochemical cells arranged in a cascade, whereby liquid electrolyte reacts in a first electrochemical cell (or group of cells) before being directed into a second cell (or group of cells) where it reacts before being directed to subsequent cells. The cascade includes 2 to n stages, each stage having one or more electrochemical cells. During a charge reaction, electrolyte entering a first stage will have a lower state-of-charge than electrolyte entering the nth stage. In some embodiments, cell components and/or characteristics may be configured based on a state-of-charge of electrolytes expected at each cascade stage. Such engineered cascades provide redox flow battery systems with higher energy efficiency over a broader range of current density than prior art arrangements.
US08785016B2 Battery pack
A battery pack includes a core pack including a unit cell; a protection circuit module electrically connected to the core pack and including a switch contact portion; a frame accommodating the core pack and the protection circuit module; and a cover including a recessed portion covering at least a part of the core pack, facing the switch contact portion, and extending toward the protection circuit module.
US08785012B2 Fuel cell bypass diode structures and attachment methods
A fuel cell system includes a fuel cell stack which includes a plurality of fuel cells contacted in series by a plurality of interconnects. The various embodiments provide systems and methods for coupling a fuel cell stack with an electric bypass module within a hot zone. The bypass module may include elements for conducting a current between interconnects in a fuel cell stack and thereby bypass a failed fuel cell that has become a resistive parasitic load.
US08785010B2 Glass substrate for a magnetic disk and magnetic disk
Provided are a magnetic disk substrate and a method of manufacturing the same, wherein the magnetic disk substrate has very few defects present on its surface with an arithmetic mean roughness (Ra) at a level in the vicinity of 0.1 nm and thus is suitable as a substrate for a magnetic disk with high recording density. The magnetic disk glass substrate is such that the arithmetic mean roughness (Ra) of the main surface of the glass substrate measured using an atomic force microscope with a resolution of 256×256 pixels in a 2 μm×2 μm square is 0.12 nm or less and the number of defects detected to have a size of 0.1 μm to 0.6 μm in plan view and a depth of 0.5 nm to 2 nm is less than 10 per 24 cm2, wherein the defects are each detected using a shift in wavelength between incident light and reflected light upon irradiating and scanning helium neon laser light with a wavelength of 632 nm on the main surface of the glass substrate.
US08785008B2 Zirconia sintered bodies with high total light transmission and high strength, uses of the same, and process for producing the same
The invention relates to the use of a sintered body obtained by subjecting a primary sintered body having a relative density of 95% or higher produced from a fine yttria-containing zirconia powder to HIP sintering at a temperature of 1,200-1,600° C. and a pressure of 50 MPa or higher. This sintered body is either a sintered body which has a total light transmittance, as measured at a thickness of 0.5 mm, of 43% or higher and a three-point bending strength of 1,700 MPa or higher or a zirconia sintered body which has a total light transmittance, as measured at a thickness of 1 mm, of 40% or higher and a three-point bending strength of 500 MPa or higher and which combines high strength and total light transmission.
US08785001B2 Organic electroluminescent devices
The present invention relates to mixtures of organic materials, to the use of these mixtures in organic electroluminescent devices, and to organic electroluminescent devices comprising these mixtures.
US08785000B2 Steel sheet with hot dip galvanized zinc alloy coating and process to produce it
Steel strip provided with a hot dip galvanized zinc alloy coating layer, in which the coating of the steel strip is carried out in a bath of molten zinc alloy, the zinc alloy in the coating consisting of: 0.3-2.3 weight % magnesium; 0.6-2.3 weight % aluminum; optional <0.2 weight % of one or more additional elements; unavoidable impurities; the remainder being zinc in which the zinc alloy coating layer has a thickness of 3-12 μm.
US08784999B2 Weldable metal article
The invention relates to an extruded or rolled clad metal article having a core metal layer and a cladding metal layer on at least one surface of the core layer, wherein the metals of the core metal layer and the cladding metal layer are each aluminum alloys, preferably an aluminum-magnesium alloy, having at least Sc in a range of 0.05% to 1%, and wherein the Sc-content in the core metal layer is lower than in the cladding metal layer. This further relates to a welded structure incorporating such a metal article.
US08784996B2 Extrusion coating composition
Multimodal polyethylene compositions are provided. Extrusion compositions including the multimodal polyethylene are provided. The extrusion composition further include a high pressure low density polyethylene and optionally other additives and/or polyethylenes. Extruded articles made from the polyethylene extrusion compositions are also provided.
US08784995B2 Grain oriented electrical steel sheet and method for manufacturing the same
A grain oriented electrical steel sheet has linear grooves for magnetic domain refinement formed on a surface thereof and may reduce iron loss by using these linear grooves, where the proportion of those linear grooves having crystal grains directly beneath themselves, each crystal grain having an orientation deviating from the Goss orientation by 10° or more and a grain size of 5 μm or more, is controlled to 20% or less, and secondary recrystallized grains are controlled to have an average β angle of 2.0° or less, and each secondary recrystallized grain having a grain size of 10 mm or more is controlled to have an average β-angle variation of 1° to 4°.
US08784990B2 Adhesive film composition for glass lamination
Provided is a resin composition based on polyalkylene carbonate for use as an adhesive film composition for glass lamination, and more particularly, to a resin composition in which a plasticizer and isocyanate are added to polypropylene carbonate or polyethylene carbonate as polyalkylene carbonate to introduce a urethane group. As such, the resin composition of the present invention can improve an adhesive strength by addition of isocyanate, and secure flexibility by using the plasticizer. In particular, an adhesive sheet based on polyalkylene carbonate can decompose a polymer laminate layer through simple heat treatment to fully collect glass when defects of glass lamination are generated, thereby reducing the loss of glass due to process failure, be stable to moisture so that transport, storage, and use thereof are not limited, and perform lamination even at a lower process temperature.
US08784989B2 Sealant compositions having a novel plasticizer
A sealant composition having from about 0.1 to about 90 weight % of a polymer selected from the group consisting of butyls, acrylics, urethanes, polysulfides, and silicone modified polymers, and at least one C4 to C8 alkyl terephthalate.
US08784986B2 Coated article and method for manufacturing same
A coated article includes a substrate and a Si—B—C—N ceramic coating deposited on the substrate by magnetron sputtering process. The Si—B—C—N ceramic coating is an amorphous coating, the weight of elemental Si in the coating is between about 30 wt % and about 60 wt % of the total weight of Si, B, C and N, the weight of elemental B in the coating is between about 10 wt % and about 20 wt % of the total weight of Si, B, C and N, the weight of elemental C in the coating is between about 10 wt % and about 20 wt % of the total weight of Si, B, C and N, the weight of elemental N in the coating is between about 20 wt % and about 30 wt % of the total weight of Si, B, C and N.
US08784983B2 Expanded porous polytetrafluoroethylene film-laminated sheet, and gasket composed of said sheet
The laminated sheet of this invention is a sheet including expanded porous polytetrafluoroethylene films laminated by thermal compression bonding, wherein the sheet has a specific surface area of 9.0 m2/g or larger and a density of from 0.4 g/cm3 to lower than 0.75 g/cm3, thereby making it possible to improve both the creep resistance and the adhesiveness between the films of the expanded porous PTFE film-laminated sheet.
US08784981B2 Stainless steel-and-resin composite and method for making same
A stainless steel-and-resin composite includes a stainless steel part and a resin part bonded to the stainless steel part. The stainless steel part has a porous film resulted from anodizing formed thereon. The porous film defines pores with an average diameter of about 100 nm-500 nm. The resin part is integrally bonded to the surface of the stainless steel part having the porous film, with portions of the resin part penetrating in the pores. The resin part mainly comprises crystalline thermoplastic synthetic resin.
US08784979B2 Thermally sprayed gastight protective layer for metal substrates
In a thermally sprayed, gastight protective layer for metal substrates, such as Fe, Ni, Al, Mg and/or Ti, the spray powder for the purpose includes at least two components. The first is a silicate mineral or rock and the second is a metal powder and/or a further silicate mineral or rock. The silicate mineral or rock component in the spray powder has an alkali content of less than 6 percent by weight.
US08784975B2 Self-aligned wafer bonding
A wafer article includes a substrate, two or more hydrophilic areas disposed on the substrate, hydrophobic areas surrounding the hydrophilic areas, and a eutectic bonding material disposed on the substrate. A wafer apparatus including two wafers having complimentary hydrophilic regions and eutectic bonding material is disclosed and a method of forming a bonded wafer articles is disclosed.
US08784973B2 Resin bonding method by photoirradiation, method for producing resin article, resin article produced by the same method, method for producing microchip, and microchip produced by the same method
A resin bonding method according to the present invention is a resin bonding method for bonding a first resin and a second resin including (I) a step of irradiating spaces containing oxygen molecules with vacuum ultraviolet light having a wavelength of 175 nm or less, the spaces being in contact with surfaces of the first and second resins; and (II) a step of, after the irradiation, subjecting the surfaces to temperature rise while the surfaces are in contact with each other, to bond the first resin and the second resin together with the surfaces serving as bonding surfaces. In the step (I), the surfaces of the first and second resins may be further irradiated with the vacuum ultraviolet light. In this case, a light amount of the vacuum ultraviolet light having reached the surfaces is preferably, for example, 0.1 J/cm2 or more and 10 J/cm2 or less.
US08784969B2 Meshwork made of ribbons
A meshwork made of ribbons (1, 2) is described which are connected with each other by way of a thermoplastic filler material. In order to provide simple constructional conditions it is proposed that the ribbons (1, 2) which are laid in at least two groups and intersect one another in groups are fixed between two cover layers (3, 4) with respect to their mutual position, which layers have an at least two-layer configuration with a bonding layer which faces the ribbons (1, 2) and is made of a thermoplastic material and with a carrier layer having a higher tensile strength, which layers are connected with each other and with the ribbons (1, 2) by way of the bonding layer.
US08784965B2 Method of creating two-sided template from a single recorded master
The embodiments disclose a method of creating two-sided template from a single recorded master, including fabricating a first template using a single recorded master, wherein the first template has a changed duty cycle and an unchanged servo arc orientation, creating a replicate of the first template, wherein the replicate has a mirrored servo arc orientation and a changed duty cycle and fabricating a second template using the replicate to produce a predetermined mirrored servo arc orientation and a predetermined duty cycle for imprinting on a second side of a patterned stack.
US08784959B2 Injection-molded composite construct
A frame is injection molded onto a group of panels to form a container. The panels extend at least partially around, and at least partially define, a cavity of the container.
US08784957B2 Flat container comprising thermoplastic resin and method for molding the same
The invention realizes easy manufacturing of a flat container molded by blow molding, in which the wall thickness of a container wall is made uniform, and which provides improved mechanical strength, heat resistance, etc. and has a good appearance.The flat container obtained by the blow molding of a polyester resin is characterized in that the container has a flatness ratio of not less than 1.3, and in that its body has a wall thickness ratio of a maximum wall thickness to a minimum wall thickness of not more than 1.6, a difference in elongation between a maximally stretched portion and a minimally stretched portion of not more than 150% in a tensile test at 95° C., a crystallinity of not less than 30%, and a difference in TMA non-load change between a maximally stretched portion and a minimally stretched portion of not more than 500 μm at 75° C. and 100° C.
US08784956B2 Resin composition for forming receiving layer, and receiving substrate; printed matter, conductive pattern, and electric circuit produced by using the resin composition
An object to be achieved by the present invention is to provide a resin composition for forming a receiving layer, the resin composition being capable of forming, among receiving layers that can carry a fluid such as an ink, a receiving layer having excellent, adhesion to various types of supports and capable of forming a receiving layer which has excellent printing properties without causing bleeding of a fluid such as an ink. The present invention relates to a resin composition for forming a receiving layer, the resin composition containing a urethane resin (A), a vinyl polymer (B), and an aqueous medium (C), in which the urethane resin (A) has an alicyclic structure in an amount of 2,000 to 5,500 mmol/kg relative to the total amount of the urethane resin (A), and a hydrophilic group.
US08784948B2 Methods and apparatuses for controlling gas flow conductance in a capacitively-coupled plasma processing chamber
Apparatuses are provided for controlling flow conductance of plasma formed in a plasma processing apparatus that includes an upper electrode opposite a lower electrode to form a gap therebetween. The lower electrode is adapted to support a substrate and coupled to a RF power supply. Process gas injected into the gap is excited into the plasma state during operation. The apparatus includes a ground ring that concentrically surrounds the lower electrode and has a set of slots formed therein, and a mechanism for controlling gas flow through the slots.
US08784947B2 Silsesquioxane compound having polymerizable functional group
To provide a composition comprising a silsesquioxane compound that is capable of producing a coating film with excellent heat resistance and scratch resistance, and that has excellent compatibility with general polymerizable unsaturated compounds as well as polymerizable unsaturated compounds with high polarity.A silsesquioxane compound comprising organic groups each directly attached to a silicon atom of the compound, at least one of the organic groups being an organic group having one or more urethane bonds and one (meth)acryloyloxy group.
US08784944B2 Plasma-spray powder manufacture technique
A ceramic thermal barrier coating having improved erosion resistance includes a metallic layer and a ceramic layer positioned on the metallic layer. The ceramic layer includes a first powder, a second powder, and a third powder. The first powder and the second powder are alloyed together prior to being mixed with the third powder.
US08784943B2 Process for guniting refractory mixes using conventional dry gunning equipment and refractory mixes for use in same
A dry refractory mix and a method for apply the dry refractory mix to a surface. One aspect of the invention utilizes gunning mixes without cement. The dry refractory mix also may include a setting agent that is homogeneously blended with the refractory mix. In operation, when used with pneumatic systems, dry refractory material is fed into a hopper of a gunnite machine, introduced into an air flow, and conveyed by air through one or more hoses to a nozzle. A liquid binder is introduced into the air flow for mixing with the suspended dry refractory material at or before the nozzle. A fitting, such as a water ring with holes, may be used for injecting the binder into the air flow containing the dry refractory material. The mixed refractory/binder material is discharged through the nozzle for application to a surface.
US08784942B2 Spray texture material compositions, systems, and methods with anti-corrosion characteristics
A system for dispensing texture material in a desired spray pattern that substantially matches an existing texture pattern on a target surface comprises an aerosol dispenser, concentrate, and propellant material. The aerosol dispenser has an inner surface comprised at least in part of tin-plated steel. The concentrate comprises a solvent/carrier comprising water, a resin/binder, filler material, a first anti-corrosion material, and a second anti-corrosion material.
US08784937B2 Glass substrates having carbon nanotubes grown thereon and methods for production thereof
Methods for growing carbon nanotubes on glass substrates, particularly glass fiber substrates, are described herein. The methods can include depositing a catalytic material or a catalyst precursor on a glass substrate; depositing a non-catalytic material on the glass substrate prior to, after, or concurrently with the catalytic material or catalyst precursor; and exposing the glass substrate to carbon nanotube growth conditions so as to grow carbon nanotubes thereon. The glass substrate, particularly a glass fiber substrate, can be transported while the carbon nanotubes are being grown thereon. Catalyst precursors can be converted into a catalyst when exposed to carbon nanotube growth conditions. The catalytic material or catalyst precursor and the non-catalytic material can be deposited from a solution containing water as a solvent. Illustrative deposition techniques include, for example, spray coating and dip coating.
US08784930B2 Transparent conductive film having high optical transmittance and method for manufacturing the same
The present invention pertains to a transparent conductive film including a conductive layer having different thicknesses so as to increase the optical transmittance while maintaining the conductivity of the transparent conductive film. The present invention also pertains to a process for the preparation of the above-mentioned transparent conductive film.
US08784924B2 Heat-expanded food products
This invention relates to heat-expanded synthetic cheese products, heat-expandable precursors for forming same, the preparation of the precursor and the cheese products, and the use of a sugar alcohol for improving the organoleptic properties and/or the volume expansion % of the heat-expandable precursors and/or heat-expanded synthetic cheese products. The invention provides a heat-expanded synthetic cheese product, comprising:—from about 20% to about 59% by weight of a milk protein or a source thereof; from about 10% to about 50% by weight of a starch; from about 2% to about 24% by weight of a sugar alcohol; from about 3% to about 15% by weight of water; wherein the heat-expanded synthetic cheese product comprises no more than 10% by weight of fat, the percentages being percentages by weight of the total product, and wherein the heat-expanded synthetic cheese product is a microwave-expanded synthetic cheese product or a radiofrequency (RP)-expanded synthetic cheese product.
US08784923B2 Raw materials, methods and fruits and vegetables pertaining to sugar content improvement, sugar component adjustment, and tastes adjustment
The present invention provides a sugar content-improving material that can prevent oxidative damage of fruits and vegetables after harvesting as well as can improve the sugar content, a method for improving the sugar content of fruits or vegetables, fruits or vegetables having an improved sugar content, a sugar component-adjusting material, a method for adjusting a sugar component of fruits and vegetables, fruits or vegetables having an adjusted sugar component, a taste-adjusting material, a method for adjusting the taste of fruits or vegetables, and fruits or vegetables having adjusted taste. The sugar content-improving material includes a breathable, permeable and flexible sheet containing proanthocyanidin and trehalose. The proanthocyanidin is contained in the sheet in a proportion of 250 to 300 mg/m2. The trehalose is contained in the sheet in a proportion of 5 g/m2.
US08784921B2 Method for concentrating lipids
As a method for an efficient concentration of lipid components from food materials, a method for concentrating lipids contained in a crustacean, which comprises heating squeezed liquid prepared by squeezing the whole crustacean or a part thereof and separating the heated squeezed liquid into solids containing lipid components and liquid containing water-soluble components. Those are useful as the method by which lipids abundantly containing the phospholipid are prepared easily and at a low cost. Furthermore, the solids containing the lipids prepared by said method or a dried product thereof, lipids extracted therefrom and a composition abundantly containing the useful lipids derived from crustaceans are useful as materials for pharmaceuticals, ingredients for foods or feed, etc.
US08784920B2 System and method for packaging
In one embodiment of an apparatus and process for packaging foodstuffs or other materials in a rigid container sealed by a flexible cover, a desired quantity of material to be packaged containing or together with some water or other liquid is placed in the container, the flexible cover is secured on the container so as to leave at least one unsealed opening, the container is heated and/or placed in a partial vacuum to bring the liquid above its boiling point to cause or permit vapor generated by the boiling liquid to expel other gases from the container through the unsealed opening, and the container is sealed while gas or vapor is still flowing out of the container through the unsealed opening.
US08784919B2 Method of preparing a tuber
The present invention is a method of preparing a tuber for consumption, with the tuber having added food ingredients in the tuber. The tuber is thoroughly cooked. The tuber is frozen to provide rigidity about the skin of the tuber, while leaving a portion of the flesh unfrozen. A portion of the flesh of the tuber is removed either prior to or after cooking. The desired added food material is inserted through a hole in the skin and into the void where flesh of the tuber was removed. The tuber may then be completely frozen for later preparation and consumption.
US08784917B2 Food product
The invention concerns a new food product (1) in the form of a meal comprising food (4) and a sauce (5), intended to be mixed for consumption of the meal, in closed packaging (1) comprising a container (2) in which the food (4) is placed and a lid (3) in which the sauce (5) is placed, the sauce being separated from the food by a seal (7) which closes off the part of the lid (3) facing the food (4) characterized in that the container (2) comprises a mechanism (11) to tear the seal (7) when the lid (3) is turned concurrently to the container (2) between a pre-tearing position of the seal (7) and a tearing position of the seal (7).
US08784916B2 Packaging for two or more bars located one above the other
A packaging for foodstuffs and/or semi-luxury products produced in the form of bars, such as chocolate bars, containing two or more bars lying on top of each other, wherein each bar is wrapped in a sheet on all sides and the bars thus wrapped are enveloped by a wrapper sheet, characterized in that all bars lie flatly on top of each other in the form of a stack of bars and all bars lying on top of each other are embraced by a single continuous wrapper sheet, namely on at least three adjacent sides of each individual bar, with all fold lines of the wrapper sheet running parallel to each other.
US08784911B2 Compositions for treatment and prevention of diabetic complications using Osteomeles schwerinae
The present invention relates to a treatment agent for diabetic complications, and a method for the treatment of diabetic complications using the same. The present invention confirmed that Osteomeles schwerinae extract and its fractions inhibited the generation of AGEs, the index for diabetic complications, inhibited the activation of aldose reductase, had anti-cataract activity, and had anti-oxidative activity. Thus, the present invention relates to a preventive and therapeutic agent for diabetic complications containing the said Osteomeles schwerinae extract and its fraction as an active ingredient.
US08784910B2 Antimicrobial compositions
The present invention provides an antimicrobial composition comprising an antimicrobial effective amount (such as a preservative, bactericidal, and/or fungicidal effective amount) of a mixture comprising at least two of: (a) lemon grass oil; (b) cinnamaldehyde, cinnamon oil, Cinnamomum cassia, cinnamon extract, cassia leaf oil, 3,4-dihydroxycinnamic acid or salt thereof, or a mixture thereof; (c) sorbic acid, or a salt thereof; (d) erythorbic acid, or a salt thereof; (e) benzoic acid, or a salt thereof; (f) arabinogalactan, galactoarabinan, or a mixture thereof; (g) a hexahydro-iso-alpha-acid, tetrahydro-iso-alpha-acid, or a mixture thereof; (h) Achillea fragrantissima (Santolina fragrantissima Forssk., lavender cotton) oil; and (i) δ-gluconolactone. The present invention also provides a product (preferably a product other than a foodstuff, pharmaceutical, or cosmetic) comprising a preservative effective amount of cinnamaldehyde or a mixture of cinnamaldehyde and one or more alkanol-dialkyl hydantoins.
US08784909B2 Mud mask with real tea leaf and method for making the same
A mud mask with real green tea leaves is described. The mud mask is made by separating a real green tea leaf batch into a first sub-batch, a second sub-batch, and a third sub-batch. The first sub-batch is ground into a fine powder, while the second sub-batch remains as whole leaves and the third sub-batch is chopped into partially chopped leaves. The fine powder and whole leaves are added to hot water for a period of time to form a brewed tea. Thereafter, the partially chopped leaves and mud components are added to the brewed tea to form a mud solution, which is mixed to form the mud product. The mud product is packaged and allowed to marinate, which allows the leaves to begin releasing their nutrients and antioxidants into the mud formula, after which the mud mask includes atypical and unusually high levels of nutrients, antioxidants and caffeine.
US08784908B1 Composition of a bone repair mixture
A composition of a bone repair mixture has a quantity of allograft particulate bone having a bone particle distribution of particle sizes less than 700 micron and a quantity of biologic carrier material intermixed with the particulate bone. The biologic carrier material is one of collagen, porous collagen or a collagen mixture. Preferably, the carrier material is exclusively collagen.
US08784906B2 Organic lubricant
A vaginal lubricant of primarily organic materials has excellent properties for relieving vaginal dryness.
US08784900B2 Antimicrobial solutions containing dichlorine monoxide and methods of making and using the same
Methods and products are provided for treating a wound or infection in a mammal or disinfecting a surface with a hypochlorous acid solution that has been activated by a catalyst. Additionally provided is a process for preparing an antimicrobial product that produces an activated hypochlorous acid solution for use as an antimicrobial.
US08784898B2 Methods of wound care and treatment
Provided are electrokinetically-altered fluids (e.g., gas-enriched electrokinetic fluids) comprising an ionic aqueous solution of charge-stabilized oxygen-containing nanostructures in an amount sufficient to provide modulation of at least one of cellular membrane potential and cellular membrane conductivity, and therapeutic compositions and methods for use in treating a wound to a surface tissue or a symptom thereof. The electrokinetically-altered fluids or therapeutic compositions and methods include electrokinetically-altered ionic aqueous fluids optionally in combination with other therapeutic agents. Particular aspects provide for regulating or modulating intracellular signal transduction associated with said inflammatory responses by modulation of at least one of cellular membranes, membrane potential, membrane proteins such as membrane receptors, including but not limited to G-Protein Coupled Receptors (GPCR), and intercellular junctions (e.g., tight junctions, gap junctions, zona adherins and desmasomes). Other embodiments include particular routes of administration or formulations for the electrokinetically-altered fluids (e.g., electrokinetically-altered gas-enriched fluids and solutions) and therapeutic compositions.
US08784897B2 Methods of therapeutic treatment of eyes
Provided are electrokinetically-altered aqueous fluids (e.g., gas-enriched electrokinetic fluids) comprising an ionic aqueous solution of charge-stabilized oxygen-containing nanostructures in an amount sufficient to provide modulation of at least one of cellular membrane potential and cellular membrane conductivity, and therapeutic compositions and methods for use in treating an irritation, infection or inflammatory eye condition, comprising administering to, by contacting the eye of a subject in need thereof a therapeutically effective amount of an electrokinetically-altered aqueous fluid. The electrokinetically-altered fluids or therapeutic compositions and methods include electrokinetically-altered ionic aqueous fluids optionally in combination with other therapeutic agents. Other embodiments include particular routes of administration or formulations for the electrokinetically-altered fluids (e.g., electrokinetically-altered gas-enriched fluids) and therapeutic compositions for use in treating eye conditions. Certain embodiments relate to cosmetic and/or therapeutic fluids and/or methods of treatment utilizing the fluids to treat a cosmetic and/or therapeutic symptom related to eye conditions and/or diseases.
US08784892B2 Method and composition for burned skin
The present invention is directed to the use of an agent selected from ethyl alcohol, isopropyl alcohol or a mixture thereof and a topically acceptable polymeric carrier in the preparation of a composition for the treatment of burns.
US08784891B2 Compositions for regenerating defective or absent myocardium
Compositions of the invention for regenerating defective or absent myocardium comprise an emulsified or injectable extracellular matrix composition. The composition may also include an extracellular matrix scaffold component of any formulation, and further include added cells, proteins, or other components to optimize the regenerative process and restore cardiac function.
US08784884B2 Pancreatic enzyme compositions and methods for treating pancreatitis and pancreatic insufficiency
Compositions of the present invention, comprising the combination of enterically coated and uncoated pancreatic enzyme-containing beads are useful for treating or preventing pancreatitis pain, and optionally disorders associated with digestive enzyme deficiencies.
US08784881B2 Liposomal curcumin for treatment of diseases
The present invention provides compositions and methods for the treatment of a human patient. The methods and compositions of the present invention include composition for the efficient loading of curcumin, comprising: an amount of a curcuminoid:liposome complex effective to load curcumin into the liposome, wherein the curcuminoids has between 2 to 9 weight percent of the total composition and the curcuminoids are natural or synthetic.
US08784877B2 Transdermal levonorgestrel device and delivery
Described are transdermal drug delivery systems for the transdermal administration of levonorgestrel, comprising a polymer matrix and levonorgestrel acetate. Methods of making and using such systems also are described.
US08784875B2 Collagen for use in the treatment of skin diseases
The invention relates to collagen for use in the treatment of inflammatory and degenerative skin diseases and damage to the skin connected therewith, such as in particular in the treatment of psoriasis, dermatitis, neurodermitis, rosacea, urticaria (hives), pruritus (itching), skin eczema and actinic keratosis. In particular, the invention relates to freeze-dried collagen in the form of layered dressings, sheets, pads or masks for the aforementioned use.
US08784870B2 Controlled release compositions for modulating free-radical induced damage and methods of use thereof
Disclosed herein are compositions and methods for the treatment of otic diseases or conditions with free-radical modulating agent compositions and formulations administered locally to an individual afflicted with an otic disease or condition, through direct application of these compositions and formulations onto or via perfusion into the targeted auris structure(s).
US08784869B2 Controlled release delivery system for nasal applications and methods of treatment
This invention relates to a gel formulation for nasal administration of a controlled release formulation of hormones to the systemic circulation and/or to the brain. The special lipophilic or partly lipophilic system of the invention leads to higher bioavailability of the active ingredient caused by sustained serum levels in plasma but also leads to a more favorable serum level profile. The special lipophilic or partly lipophilic system also allows for the modulation of brain functioning. The invention also relates to the nasal administration of steroid hormones for treatment of female sexual dysfunction (FSD) or female arousal disorder.
US08784868B2 Degradable therapeutic delivery device
A biodegradable biodelivery device is disclosed. The biodelivery device is formed from a polymer comprising the reaction product of a polyol and a polyacid. When exposed to water, the polymer degrades through hydrolysis. Of particular advantage, the polymer can be formed so as to be elastic and flexible. In one embodiment, the polymer is formed into a vaginal insert. As the polymer degrades, the polymer releases acid to a vaginal environment for decreasing the pH of the environment.
US08784864B2 Bone repair material and method for producing the same
Bone repair materials are disclosed, from which ions are hardly eluted in living body and which are superior in apatite-forming ability and resistance to apatite peeling and have a scratch resistance high enough for practical use. The material comprises a substrate made of titanium or titanium alloys, and a surface layer, made substantially of titanium oxide, along the surface of the substrate. The substrate has on the surface thereof irregularities of from 1 nm to 10 μm in average in both width and depth. The layer has a zeta potential of +4.5 mV or more under an aqueous solution environment of pH 6 to 8, and a critical scratch resistance of 35 mN or more when vibration 100 μm in amplitude is added to a stylus with a spring constant of 200 g/mm on the surface layer and the stylus is moved at a rate of 10 mm/sec under a load increasing at a rate of 100 mN/min.
US08784862B2 Compounds and method for coating surfaces in a hemocompatible manner
The invention concerns oligosaccharides and polysaccharides as well as the use of these oligosaccharides and/or polysaccharides, which contain the sugar unit N-acylglucosamine or N-acylgalactosamine for the production of hemocompatible surfaces as well as methods for the hemocompatible coating of surfaces with said oligosaccharides and/or polysaccharides, which imitate the common biosynthetic precursor substance of heparin, heparan sulphates and chitosan. The invention further describes methods for producing said oligosaccharides and/or polysaccharides and discloses various possibilities of using hemocompatibly coated surfaces. The invention relates particularly to the use of said oligosaccharides and/or polysaccharides on stents with at least one according to invention deposited hemocompatible coating, which contains an antiproliferative, antiinflammatory and/or antithrombotic active agent, methods for the preparation of said stents as well as the use of said stents for the prevention of restenosis.
US08784861B2 Swellable fiber- and microfiber-forming polyether-esters and applications thereof
Biomedical and tissue engineering devices, such as surgical sutures and microporous scaffolds, respectively, which undergo swelling and increase in dimensions when placed in aqueous environments such as living tissues, are produced by the melt-spinning or electrostatic spinning into strong monofilament and multifilament yarns or microfibrous fabrics, respectively. Such devices are formed from especially high molecular weight crystalline polyether-esters having a minimum inherent viscosity of 0.8 dL/g and heat of fusion of at least 5 J/g, wherein the polyether-esters are made by grafting to a polyester component a polyether glycol component having a minimum molecular weight of about 1 kDa with at least one cyclic monomer.
US08784860B2 Local administration of a combination of rapamycin and cilostazol for the treatment of vascular disease
Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the formation of blood clots.
US08784857B2 Articles incorporating absorbent polymer and ceragenin compound
An absorbent article includes an absorbent polymer and a ceragenin compound. The ceragenin compound has a sterol group and a plurality of cationic groups that mimic naturally occurring antimicrobial peptides. The ceragenin compound is associated with the absorbent polymer such that upon absorption of a fluid, the ceragenin compound is incorporated or maintained in the absorbent article.
US08784856B2 Meadowfoam-based bioherbicide products
Particular aspects provide methods for converting glucosinolate in a glucosinolate-containing plant material to glucosinolate breakdown products (GBPs), comprising: providing an amount of processed glucosinolate-containing plant material, the processed material being depleted of oil and glucosinolate converting enzyme activity by virtue of said processing; providing an amount of glucosinolate converting enzyme activity; mixing the processed material with the amount enzyme activity; hydrating the mixture; and incubating the hydrated mixture, wherein the glucosinolates are enzymatically converted to GBPs. Preferably, the processed plant material comprises a oilseed-derived seedmeal material (e.g., meadowfoam seedmeal) from which the oil has been removed by the processing (e.g., solvent extraction and/or heat treatment). In particular embodiments, the glucosinolate converting enzyme activity comprises at least one of a myrosinase activity and a nitrile-forming activity. Additional aspects provide low-fat compositions (e.g., herbicide, fungicide, insecticide, bacteriostatic or bactericidal, cosmetic, cosmeceutical or pharmaceutical) comprising GBPs derived from a glucosinolate-containing plant material.
US08784855B2 Pesticides based on vicinal diols
Pesticides based on vicinal diols, are available to control arthropod ectoparasites such as Pediculus Humanus, Dermatophagoides pteronyssinus, Musca domestica, the Blattidae, Blatella Germanica, and Periplaneta Americana, by introducing to the locus of an infestation of the pest, a composition containing as active ingredient a vicinal diol.
US08784854B2 Cosmetic product comprising UV-blocking cosmetic composition impregnated into expanded urethane foam
The present invention relates to a cosmetic product comprising a UV-blocking W/O or O/W composition of low viscosity packaged in a compact-type container. More specifically, the invention relates to a UV-blocking cosmetic product prepared by impregnating a UV-blocking W/O or O/W cosmetic composition of low viscosity into expanded urethane foam, preparing a compact formulation from the expanded urethane foam impregnated with the composition, and then packaging the compact formulation in a cosmetic container. Thus, the UV-blocking cosmetic product is convenient for the user to carry and use and also has a skin-cooling effect.
US08784852B2 Topical skin care composition
The present invention is directed to a topical skin care composition. The composition has the unique ability to treat acne without drying out the user's skin. In particular, the composition includes a base, an antibacterial agent, at least one anti-inflammatory agent, and at least one antioxidant. The antibacterial agent may be benzoyl peroxide.
US08784851B2 Topical formulations containing sporopollenin
Topical formulation containing an active substance which is chemically or physically bound to, or encapsulated within, an exine shell of a naturally occurring spore. The active substance can be released from the exine shell on application to a living or non-living surface. The invention may be used to provide gradual release of an active substance over a period of time subsequent to application of the formulation to the surface.
US08784841B2 Therapeutic use of at least one botulinum neurotoxin in the treatment of pain associated with diabetic neuropathy
The present invention relates to at least one botulinum neurotoxin for treatment of prevention of pain associated with diabetic neuropathy wherein said botulinum neurotoxin is prepared for local administration, wherein the local administration is not in the central nervous system (CNS), and wherein pain is treated at a site distant to the site of administration.
US08784840B2 Method for screening modulators of apoptosis
The use and screening of modulators of apoptosis is disclosed. The modulators may be, for example, modulator of NF-κB activity. The modulators may be used, for example, in the treatment of NF-κB-mediated diseases, conditions, and injuries.
US08784839B2 Attenuated live vaccines
Disclosed is an attenuated flavivirus live vaccine comprising a flavivirus mutant, characterized in that the flavivirus mutant has a deletion in the capsid protein of at least more than 4 successive amino acids, wherein the carboxy-terminal hydrophobic region is not affected by the deletion.
US08784832B2 Synthetic antigen based on the ligand domain of the Plasmodium vivax duffy binding protein
The disclosure provides compositions that are useful for eliciting a strain-transcending immune response in an animal or human directed against the blood-stage of the malarial parasite Plasmodium vivax. The compositions are based on the ligand domain of Plasmodium vivax Duffy binding protein (PvDBPII). Polar charged polymorphic residues within the dominant strain-specific B-cell epitope were mutated to uncharged residues (e.g. serine, alanine and threonine). This DEKnull variant of PvDBPII produced in bacteria can be purified and refolded in vitro to mimic conformation and erythrocyte binding function of native DBPII. Immunogenicity of DEKnull was confirmed by administration to mice. Compared to the naturally-occurring, strain variant DBPII, DEKnull elicits antibodies that are more broadly reactive with different strain variants of DBPII and enhances production of functional inhibitory antibodies to the shared protective epitopes of native DBPII.
US08784831B2 P. gingivalis antigenic composition
The present invention provides an antigenic composition, the composition comprising at least one recombinant protein. The recombinant protein comprises at least one epitope. The epitope is reactive with an antibody which is reactive with a polypeptide having the sequence set out in SEQ. ID. NO. 3 or SEQ. ID. NO. 5. The invention also provides methods and compositions for the production of the recombinant protein. Also provided are methods for the diagnosis, treatment and prevention of P. gingivalis infection.
US08784830B2 Antigen peptide and use thereof
In order to provide an effective vaccine against infection with Propionibacterium acnes, the present invention provides a peptide which is a peptide consisting of a specific amino acid sequence or a peptide consisting of an amino acid sequence derived from the specific amino acid sequence by deletion, substitution, insertion, or addition of one or more amino acids, the peptide suppressing, by immune response, inflammation caused by infection with Propionibacterium acnes.
US08784827B2 Chimeric fusion proteins and virus like particles from Birnavirus VP2
The field of the invention refers to chimeric Virus Like Particles (VLP) derived from Birnavirus chimeric VP2 protein. In particular, the invention refers to chimeric VP2 fusion proteins which incorporate insertions and/or substitutions with one or more amino acids or particular peptide of interest while maintaining the capacity to assemble in the form of VLP. The invention identifies particular insertion and/or substitutions sites within VP2 P loop regions and outside said P loop regions. The invention also incorporates methods for the identification of preferred insertion and substitution sites within VP2 for the incorporation of particular amino acids and peptides of interest. The resulting chimeric VLP are of interest in the design of therapeutic and prophylactic vaccines as well as in the design of drug delivery systems, carriers for DNA and RNA in gene therapy, as targeted agents, in the development of antitoxins, and as diagnostic reagents.
US08784820B2 Plasminogen-activating antibody, use and producing method thereof and agent including the same
An antibody for activating plasminogen is provided. The antibody is produced from a hybridoma cell line deposited on Nov. 24, 2011 under accession number BCRC 960433 at Food Industry Research and Development Institute, 331 Shih-Pin Road, Hsinchu 300, Taiwan. The uses and producing method of the antibody, and an agent including the antibody used for treating stroke, myocardial infarction or syndromes cause by thrombus are also disclosed.
US08784818B2 Anti-VEGFR-3 antibody compositions
The present invention provides anti-VEGFR-3 monoclonal antibodies, pharmaceutical compositions containing said antibodies and uses of said antibodies in the treatment of disease.
US08784810B2 Treatment of amyloidogenic diseases
The invention provides preferred dosage ranges, maximum concentrations, average concentrations and monitoring regimes for use in treatment of Alzheimer's disease using antibodies to Aβ. The invention also provides monitoring regimes that as can assess changes in symptoms or signs of the patient following treatment.
US08784795B2 Methods for determining personalized treatment compositions for prostate cancer and breast cancer
The present disclosure provides methods for selecting a treatment composition, or therapy, for the treatment of a cancer, such as prostate or breast cancer, in a patient wherein the treatment composition includes administering a combination of at least two components selected from two different classes of compounds. Methods for treating a patient using the selected treatment composition are also provided, together with methods for monitoring the efficacy of the treatment composition during a treatment period.
US08784790B2 Method for treating chronic wounds with an extracellular polymeric substance solvating system
Chronic wounds may be treated by debriding necrotic and other devitalized tissue from the wound, and applying to the wound an extracellular polymeric substance solvating system comprising a metal ion sequestering agent, surfactant and buffering agent. The solvating system disrupts biofilms which may be present in the wound and aids or enables the resumption of normal healing.
US08784788B2 Gel carrier for releasing active ingredients
A gel carrier for releasing active ingredients is formed from a co-polymer blend and an active ingredient blend. The co-polymer blend and active ingredient blend are combined and allowed to cool to a desired temperature. When the gel carrier floats in, is immersed, or is exposed to water-based materials, active ingredients are leached out of the gel carrier.
US08784782B2 Compounds comprising linked heteroaryl moieties and their use as novel umami flavor modifiers, tastants and taste enhancers for comestible compositions
The inventions disclosed herein relate to the discovery of the use of compounds having the formula shown below and certain subgenera or species thereof, as flavor or taste modifiers, particularly, savory (“umami”) taste modifiers, savory flavoring agents and savory flavor enhancers in foods, beverages, and other comestible compositions.
US08784781B2 Manufacture of chewing gum product with radiofrequency
The present invention features a process for making a chewing gum product including the steps of forming a powder blend containing a gum base into the desired shape of the chewing gum product and applying radiofrequency energy to the shape for a sufficient period of time to soften the gum base to fuse the shape into the chewing gum product.
US08784780B2 High oil-content emollient aerosol foam compositions
Described herein are high oil-content emulsions and compositions for the treatment of inflammatory skin disorders. The emulsions may be formulated as aerosol compositions. The aerosol propellant may be a hydrofluoroalkane propellant. The emulsions or compositions may comprise active agents, such as corticosteroids. Also described are methods of treating inflammatory skin disorders, comprising the step of applying to an affected area of a subject in need thereof a therapeutically-effective amount of an inventive emulsion or aerosol composition.
US08784779B2 Color change of chalcone-containing oral care formulations
Oral care compositions and methods are described in which the composition includes a chalcone color change component, which may be phenyl-3-methoxy-4-hydroxystyryl ketone. The color change component is induced to change colors by addition of saliva and/or by a change in pH of the composition. The composition and methods provide benefits including providing visual cues to the user.
US08784773B2 Hydrogel nanocomposite wound dressing and a method of synthesizing the same
The various embodiments herein provide hydrogel nanocomposite wound dressing comprising a polymeric basal matrix, a reinforcing agent, a biological sensor and an antibiotic for a slow release in a wound when applied. The polymeric basal matrix is made up of polyvinyl alcohol polymer with an amount of 1-15% by weight. The reinforcing agent comprises clay nanoparticles to inhibit a sudden drug release. The clay nanoparticles comprise montmorillonite nano particles with an amount of 0-2% by weight. The biological sensor is a peptide chain. The peptide chain is thrombin sensitive with an amount from 50 to 200 mg. The antibiotic is gentamycine with an amount of 1-3% by weight. The embodiments herein also provide a method of synthesizing the hydrogel nanocomposite wound dressing.
US08784769B2 Polyelectrolyte multilayer thin film catalyst and method for producing same
Disclosed herein is a catalyst, including, in one example: a carrier, a polymer electrolyte multilayer film formed on the carrier, and metal particles dispersed in the polymer electrolyte multilayer film. The catalyst can be easily prepared, and can be used to produce hydrogen peroxide in high yield in the presence of a reaction solvent including no acid promoter.
US08784766B1 Diamond synthesis employing nanoparticle seeds
Iron nanoparticles were employed to induce the synthesis of diamond on molybdenum, silicon, and quartz substrates. Diamond films were grown using conventional conditions for diamond synthesis by hot filament chemical vapor deposition, except that dispersed iron oxide nanoparticles replaced the seeding. This approach to diamond induction can be combined with dip pen nanolithography for the selective deposition of diamond and diamond patterning while avoiding surface damage associated to diamond-seeding methods.
US08784761B2 Single absorber vessel to capture CO2
A system for removing carbon dioxide from a flue gas stream is provided, the system comprising an absorber vessel configured to receive a flue gas stream, the absorber vessel comprising a first absorption stage configured to receive the flue gas stream and contact it with a first ionic solution, a second absorption stage configured to receive flue gas which has passed the first absorption stage and contact it with a second ionic solution, a first sump vessel, and a second sump vessel. Furthermore, a method for removing CO2 from a flue gas stream containing CO2 is provided, the method comprising the steps of a) contacting a flow of a first ionic solution comprising NH3 with a flue gas stream to remove a first portion of CO2 from the flue gas stream, b) collecting the used ionic solution from step a) in a first sump vessel, c) recycling ionic solution from the first sump vessel to step a), d) contacting a flow of a second ionic solution comprising NH3 with the flue gas stream to remove a second portion of CO2 from the flue gas stream, e) collecting the used ionic solution from step d) in a second sump vessel, and f) recycling ionic solution from the second sump vessel to step d).
US08784759B2 NOx storage catalyst with reduced Rh loading
The present invention relates to a nitrogen oxide storage catalyst comprising: a substrate; a first washcoat layer disposed on the substrate, the first washcoat layer comprising metal oxide support particles and a nitrogen oxide storage material comprising at least one metal compound selected from the group consisting of alkaline earth metal compounds, alkali metal compounds, rare earth metal compounds, and mixtures thereof, at least a portion of said at least one metal compound being supported on the metal oxide support particles; and a second washcoat layer disposed over the first washcoat layer, said second washcoat layer comprising Rh, wherein the first washcoat layer contains substantially no Rh, and wherein the second washcoat layer is disposed on 100-x % of the surface of the first washcoat layer, x ranging from 20 to 80.
US08784753B2 Thermal cycler with self-adjusting lid
A thermal cycling instrument for PCR and other reactions performed on multiple samples with temperature changes between sequential stages in the reaction procedure is supplied with a thermal block to provide rapid changes and close control over the temperature in each sample vessel and a pressure plate incorporated into a motorized lid that detects anomalies in the reaction vessels or in their positioning over the thermal block, and automatically adjusts the plate position to achieve an even force distribution over the sample vessels.
US08784750B2 Automatic analyzer using a sample container having an information recording member
A sample is contained in a sample container and a physical relationship between the sample and a sample ID thereof is established. However, after the sample ID is read by a bar code reader and the sample is transferred to an analysis-dedicated small sample container, the sample ID and the sample are separated from each other. Following the end of analysis, therefore, the sample ID must be merged with a corresponding analysis result. A read/write-enable ID carrier is provided on an analysis-dedicated sample container into which the sample is pipetted or on a tank for holding the analysis-dedicated sample container. When the sample is pipetted or when the analysis-dedicated sample container is moved, the sample ID and other information are transferred to the read/write-enable ID carrier.
US08784747B2 Fragrance dispenser for use with portable electronic device
A cover for holding and protecting a scent insert for use with a portable electronic device or other electronic device such as an IPOD, IPAD, MP3 player, laptop, for example, including a pocket for holding a removable scented insert. The pocket is an integral part of the cover or a removable pocket which is held on to the outside of the cover with an adhesive, for example. The aromatic insert is a scent impregnated porous plastic insert or plastic insert having a permeable layer sealed with nonpermeable peelable layers of plastic or paper film wherein a top layer is removed as desired, thus releasing the desired aroma. The exterior surface of the pocket is porous or includes apertures or slits for transferring the scent outside of the pocket insert holder.
US08784746B2 Systems, components, and methods for sterilizing medical waste
To improve throughput of biomedical waste treatment, the present inventors devised an exemplary ozone-based system including a shredder, a roll-off treatment bin with ozone injectors, an ozone source, and a controller. The controller monitors electric current drawn by the shredder as shredded waste enters the ozone-enriched treatment bin. In response to current falling below a predetermined low level, indicating that a batch of waste has been shredded and loaded into the treatment bin, the controller starts a treatment timer. The timer measures elapsed ozone treatment or exposure time. If additional waste is added to the shredder and a subsequent low-current condition is detected, the controller restarts the treatment timer. Expiration of the timer indicates that the waste in the roll-off bin is sterilized and ready for transport to landfills. The exemplary system provides continuous waste processing and promises to boost throughput by 50% over some conventional ozone-based waste-treatment systems.
US08784745B2 Methods for manipulating liquid substances in multi-chambered receptacles
A receptacle having a plurality of interconnected chambers arranged to permit multiple process steps or processes to be performed independently or simultaneously. The receptacles are manufactured to separate liquid from dried reagents and to maintain the stability of the dried reagents. An immiscible liquid, such as an oil, is included to control loading of process materials, facilitate mixing and reconstitution of dried reagents, limit evaporation, control heating of reaction materials, concentrate solid support materials to prevent clogging of fluid connections, provide minimum volumes for fluid transfers, and to prevent process materials from sticking to chamber surfaces. The receptacles can be adapted for use in systems having a processing instrument that includes an actuator system for selectively moving fluid substances between chambers and a detector. The actuator system can be arranged to concentrate an analyte. The detector can be used to detect an optical signal emitted by contents of the receptacle.
US08784744B2 Device making phosphorus by thermal process
The present invention discloses an apparatus for thermally refining phosphorus. The apparatus comprises: a melting furnace for melting rock phosphate into melts, including a feed port and a melt outlet; and a reduction-oxidation furnace including a furnace body which gas a melt inlet, a slag outlet, and a fume outlet, and a blow gun, wherein the melt inlet and the melt outlet are in communication with each other and wherein the blow gun has an end inserted into the furnace body. The content of impurities in fumes containing phosphorus pentaoxide is low, and the phosphorus pentaoxide can be easily extracted with a high purity of the phosphorus pentaoxide and at low cost by means of the apparatus for thermally refining phosphorus according to the present invention.
US08784740B2 Exhaust gas denitrizer
An exhaust gas denitrizer removes nitrogen oxides from rejoined exhaust gas using a denitrification reactor after supplying ammonia gas to the rejoined exhaust gas made up of main exhaust gas cooled by a fuel economizer by flowing through a main duct and bypass exhaust gas maintained at high temperature by flowing through a bypass duct adapted to bypass the fuel economizer. At a meeting place between the main exhaust gas and bypass exhaust gas in the main duct, three partition plates are installed with plate surfaces turned to an inflow direction of the bypass exhaust gas, partitioning a main exhaust gas channel into a plurality of sub-channels. Upstream-side ends of the partition plates face the incoming bypass exhaust gas by being shifted from one another toward an upstream side of the main exhaust gas starting from an inflow side of the bypass exhaust gas.
US08784737B2 Introducing an analyte into a chemical analyzer
A chemical pre-concentrator includes a conduit defining a flow path between two ends and having a heating element disposed within the conduit, such that the heating element has at least one sorbent material deposited directly on at least a portion of a conductive surface of the heating element. Some such heating elements are in the form of electrically conductive strips defining both a plurality of apertures through the strip and a series of undulations spaced along the flow path.
US08784734B2 Reusable sheaths for separating magnetic particles
An assembly that utilizes reusable sheaths for covering magnetic rods for collecting particles in an inverse magnetic particle process. The magnetic rod is removed from the reusable sheath to release particles at the same or a different location. The reusable sheaths can be assembled in a cylindrical plate, which can be rotated to position a clean sheath for each step of the inverse magnetic particle process. When not being used for particle separation, the sheaths can be washed of potentially contaminating solution in wash receptacles.
US08784732B1 Autoclave and method for treating regulated medical waste using injection of bursts of stream
A steam autoclave for treating Regulated Medical Waste that uses a condensate drainage system that provides for condensate drainage while the steam autoclave chamber remains pressurized during the steam treatment cycle to create pressure variations in the autoclave which are used to initiate the introduction of repeated bursts of steam into the waste during the steam treatment cycle. The repeated bursts of steam into the autoclave during the steam treatment cycle agitates the steam and waste contained in the autoclave, thereby enhancing steam penetration into the waste being treated and thereby enhancing biological kill efficacy.
US08784731B2 Foot/footwear sterilization system
A foot/shoe sanitizing system includes a housing having at least one opening and at least one ultraviolet emitting device supported within the housing. The ultraviolet emitting devices direct ultraviolet light around and/or through the set of foot/shoe support bars towards the foot or shoe placed on the foot/shoe support bars. The ultraviolet emitting devices are controllably powered to emit ultraviolet light and/or ozone onto the foot/shoe. In a preferred embodiment, the ultraviolet emitting device emits light that includes short wavelength ultraviolet light, causing the formation of ozone in the area of the shoe, thereby killing pathogens that are not easily killed with ultraviolet light alone. The system includes a sheet of activated carbon for catalyzing the ozone into harmless concentrations of carbon monoxide and carbon dioxide.
US08784728B2 Micro-grained, cryogenic-milled copper alloys and process
There is provided cryogenic milled copper alloys and methods of making the alloys. The alloys are fine grained and possess desirable physical properties stemming from the fine grain size. Embodiments include desirable physical properties, such as potentially high strength. Some embodiments of the cryogenic milled copper alloys may also be tailored for ductility, toughness, fracture resistance, corrosion resistance, fatigue resistance and other physical properties by balancing the alloy composition. In addition, embodiments of the alloys generally do not require extensive or expensive post-cryogenic milling processing.
US08784727B2 Molten metal furnace
An improved molten metal furnace including an enlarged buffer plate of nickel-based superalloy material which seals and separates the furnace burners from the product to be heated. The seal from the buffer plate provides for the creation of a generally inert atmosphere for the bath of molten metal. Additionally, angling the interconnecting passageways between the furnace regions improve the thermal efficiency of the circulating molten metal.
US08784722B2 Method and apparatus for producing hook fasteners
Apparatus and process are described for forming projections on a substrate for use as hook-type fasteners in touch fastening systems, wherein vibration energy may be used to soften a substrate which may be positioned between a mold and a source of vibration. The mold may include a plurality of cavities into which the softened substrate may be forced to form the projections. The substrate may comprise a film, sheet, web, composite, laminate, etc. and be useful as an attachment strip for temporary or permanent fastening. The source of vibration may be an ultrasonic horn. The process to form such projections may be operated in a continuous, semi-continuous or intermittent manner.
US08784717B2 Process and apparatus for moulding and curing tyres
A process for molding and curing tires, includes introducing a green tire into a curing mold, the mold including a first sidewall plate and a second sidewall plate, a ring of circumferential sectors circumscribing a mold cavity, an expandable bladder delimited by a membrane, and at least one bead molding ring which is movable between a first contracted operating position and a second extended operating position; and molding and curing the green tire in the curing mold; and between introducing the green tire and molding and curing it, the process includes extending the at least one bead molding ring from the first contracted operating position to the second extended operating position; forming a circumferential bearing surface which bears against a first axially inner surface portion of a first annular fixing structure of the green tire; pressing a second axially inner surface portion of the first annular fixing structure by expanding the membrane at a pre-molding pressure which is lower than a molding pressure, so as to bring the first annular fixing structure into contact with the first sidewall plate thus shaping an axially outer surface portion of the first annular fixing structure by means of the first sidewall plate and shaping the first axially inner surface portion of the first annular fixing structure by means of the circumferential surface of the at least one bead molding ring.
US08784715B2 Structure of parts made from plural composite pieces and method of building those parts
A pre-molded part is formed by pre-molding an insert with a pre-molded member, and then the pre-molded part is inserted into an over-molded member composed of thermo plastic resin. After applying a heat treatment with a temperature lower than a crystalline melting point of the pre-molded part to the pre-molded part surrounding the insert, a firm contact between the insert and the resin surrounding the insert without a gap at the interface between those parts is obtained.
US08784713B2 Method of making articles with super-hydrophobic and/or self-cleaning surfaces
Super-hydrophobic and self-cleaning articles produced by imprinting exposed surfaces with suitable fine-grained and/or amorphous metallic embossing dies to transfer a dual surface structure, including ultra-fine features less than or equal to 100 nm embedded in and overlaying a surface topography with macro-surface structures greater than or equal to 1 micron are disclosed.
US08784704B2 Broadband artificial dielectric with dynamically optical control
A material is provided for switching dielectric constant between distinct first and second values responsive to electromagnetic radiation having a specified energy. The material includes a medium transparent to the radiation and a plurality of particulates. Each particulate has a dipole that assumes one of distinct first and second parameters that correspond to the first and second values. The particulates are suspended within the medium. The parameters are either dipole span or charge strength. The dipole of each particulate sets to the first parameter by default and sets to the second parameter in response to the radiation. The particulates can be composed from undoped semi-insulating gallium arsenide. The medium can be polymethylmethacrylate, for example.
US08784703B2 Method of making highly-confined semiconductor nanocrystals
A method of making a colloidal solution of high confinement semiconductor nanocrystals includes: forming a first solution by combining a solvent, growth ligands, and at most one semiconductor precursor; heating the first solution to the nucleation temperature; and adding to the first solution, a second solution having a solvent, growth ligands, and at least one additional and different precursor than that in the first solution to form a crude solution of nanocrystals having a compact homogenous semiconductor region. The method further includes: waiting 0.5 to 20 seconds and adding to the crude solution a third solution having a solvent, growth ligands, and at least one additional and different precursor than those in the first and second solutions; and lowering the growth temperature to enable the formation of a gradient alloy region around the compact homogenous semiconductor region, resulting in the formation of a colloidal solution of high confinement semiconductor nanocrystals.
US08784699B2 In-Ga-Zn-type oxide, oxide sintered body, and sputtering target
An oxide including indium (In), gallium (Ga) and zinc (Zn), wherein diffraction peaks are observed at positions corresponding to incident angles (2θ) of 7.0° to 8.4°, 30.6° to 32.0°, 33.8° to 35.8°, 53.5° to 56.5° and 56.5° to 59.5° in an X-ray diffraction measurement (CuKα rays), and one of diffraction peaks observed at positions corresponding to incident angles (2θ) of 30.6° to 32.0° and 33.8° to 35.8° is a main peak and the other is a sub peak.
US08784698B2 Surface structures for enhancement of quantum yield in broad spectrum emission nanocrystals
Disclosed are inorganic nanoparticles comprising a body comprising cadmium and/or zinc crystallized with selenium, sulfur, and/or tellurium; a multiplicity of phosphonic acid ligands comprising at least about 20% of the total surface ligand coverage; wherein the nanocrystal is capable of absorbing energy from a first electromagnetic region and capable of emitting light in a second electromagnetic region, wherein the maximum absorbance wavelength of the first electromagnetic region is different from the maximum emission wavelength of the second electromagnetic region, thereby providing a Stokes shift of at least about 20 nm, wherein the second electromagnetic region comprises an at least about 100 nm wide band of wavelengths, and wherein the nanoparticle exhibits has a quantum yield of at least about 10%. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
US08784695B2 Method for manufacturing polyurethane nanocomposite comprising expanded graphite and composition thereof
Disclosed herein is a method of manufacturing a nanocomposite using expanded graphite. The method is characterized in that monomers are formed into a polymer between the plate-shaped layers of the expanded graphite, and the polymer is intercalated therebetween, so that the plate-shaped layers of the expanded graphite are completely exfoliated or are formed into graphene, with the result that the expanded graphite is completely dispersed in a polymer matrix. The nanocomposite manufactured by this method has excellent electrical conductivity and thermal conductivity because the expanded graphite is uniformly dispersed in this nanocomposite.
US08784689B2 Color-changing composition
The present invention relates to a color-changing composition and a multiple-component material including a substrate and a printed layer on the substrate. The printed layer includes a color-changing composition to indicate a change in condition, such as a change in wetness. The color-changing composition includes a matrix-forming component, a leuco dye, a Lewis Acid, a neutral surfactant and an organic solvent.
US08784684B2 Polymerizable compound, polymerizable liquid crystalline composition, macromolecular compound and film
A compound which has a benzoxazinone ring and an aromatic ring that directly bonds to the benzoxazinone ring, and has a mesogenic core substituted by a substituent having a polymerizable functional group is excellent in terms of durability, colorless, and exhibits a high Δn while having an azomethine bond.
US08784683B2 Liquid crystalline polyester composition, method of producing the same and molded product manufactured from the same
A liquid crystalline polyester composition contains at least 100 parts by weight of liquid crystalline polyester having different structural units and 10 to 100 parts by weight of glass fiber, wherein the glass fiber has a weight-average fiber length (Mw) of 200 to 500 μm, and content of specific glass fiber having fiber length of not less than 1500 μm is 0.1 to 5.0 percent by weight to a total amount of the glass fiber.
US08784678B2 Reverse iron ore flotation by collectors in aqueous nanoemulsion
The present invention relates to a process for concentration of silicate-containing minerals and ores by froth flotation, in particular to a reverse flotation process, in the presence of a finely dispersed collecting agent characterized by a specific droplet size distribution.
US08784676B2 Waferless auto conditioning
A method for reducing contamination in an etch chamber is provided. A substrate with a metal containing layer is placed in the etch chamber. The metal containing layer is etched, producing nonvolatile metal residue deposits on surfaces of the etch chamber, wherein some of the metal residue of the metal residue deposits is in a first state. The substrate is removed from the etch chamber. The chamber is conditioned by converting metal residue in the first state to metal residue in a second state, where metal residue in the second state has stronger adhesion to surfaces of the etch chamber than metal residue in the first state.
US08784673B2 Highly organized single-walled carbon nanotube networks and method of making using template guided fluidic assembly
Methods for fabricating templates for nanoelement assembly and methods for fluid-guided assembly of nanoelements are provided. Templates are fabricated by plasma modification of surface hydrophilicity and production of a network of hydrophobic trenches having a hydrophilic bottom surface. Single-walled carbon nanotubes (SWNT) can be assembled into stable films, ribbons, and wires of nanoscale thickness and nanoscale or microscale width and length. The nanofilm assemblies prepared according to the invention are highly conductive and can be used in the fabrication of a wide variety of microscale and nanoscale electronic devices.
US08784669B2 Oxidation process
A batch process for the treatment of an aqueous solution so that the treated product is more desirable for disposal includes obtaining an influent batch of aqueous solution for treatment, treating the batch of solution by an advanced oxidation process. The advanced oxidation process including causing ozone to be mixed with the solution, maintaining the mixture of solution and ozone at a pressure above atmospheric for a time of at least two seconds. In a preferred embodiment of the process, the process includes continuously recirculating the fluid to be treated, through a recirculation conduit, the recirculation conduit including an ozone injector and the ozone injector is adapted to inject ozone into the aqueous solution as the aqueous solution circulates through an ozone injector. Influent to be treated may be selected from the group including sewage, septage, leachate, ballast or other aqueous solutions where it is desirable to treat the fluid prior to disposal, further treatment, or reuse. The process is carried out to improve a level of disinfection and/or denutrification of the effluent.
US08784652B2 Swimming pool cleaner with a rigid debris canister
A swimming pool cleaner of the type movable along an underwater pool surface to clean debris therefrom. The pool cleaner includes a body having a debris inlet and a debris outlet. A rigid debris-collection canister is secured to the body over the debris outlet to collect debris in the rigid canister and pass filtered water either back into the pool or to a remote suction system such that the collected debris remain at the pool-cleaner body for easy maintenance while allowing free flow of water through the rigid canister. The rigid canister is shaped to minimize obstructions to the pool cleaner movement in the pool by providing improved buoyancy and limiting entrapment of the cleaner by underwater pool structures. The cleaner body is adapted for securement of either a water-suction hose connected to a remote suction system or a venturi-line structure connected to a water-flow line fed by a remote pump such that the pool cleaner is interchangeably usable as a suction cleaner and as a pressure cleaner.
US08784645B2 Process for producing hydrocarbon oil
The method for manufacturing a hydrocarbon oil of the present invention comprises a first step wherein a plurality of reaction zones filled with a specific catalyst is disposed in series and a feedstock oil containing an oxygen-containing hydrocarbon compound derived from an animal or vegetable oil is supplied and hydrotreated under the conditions of a hydrogen pressure of 1 MPa or more and 10 MPa or less in each of the reaction zones; and a second step wherein hydrogen, hydrogen sulfide, carbon dioxide and water are removed from a product to be treated obtained in the first step to obtain a hydrocarbon oil. Among the plurality of reaction zones, the inlet temperature of the reaction zone disposed on the most upstream side is 150° C. or more and 250° C. or less, the inlet temperature of the second most upstream reaction zone or below is equal to or higher than the condensation temperature of water, and the outlet temperature of the reaction zone disposed on the most downstream side is 260° C. or more and 360° C. or less. The feedstock oil comprises a recycled oil containing a specific amount of a part of the hydrocarbon oil obtained in the second step and a specific amount of a sulfur-containing hydrocarbon compound.
US08784642B2 Lubricating oil composition for lubricating automotive engines
A lubricating oil composition of SAE viscosity grade 0W20 which comprises a base oil and additive components comprising a nitrogen-containing ashless dispersant, an alkaline earth metal-containing detergent, a phosphorus-containing wear inhibitor, an oxidation inhibitor and a viscosity index improver and which shows a viscosity index of 200-240, a HTHS viscosity of not less than 2.9 mPa·s s at 150° C. and a Noack evaporation loss of not more than 13% favorably gives a high fuel economy and high wear inhibition to a four cycle gasoline engine of motorcycles and a diesel engine mounted on motor cars equipped with an exhaust gas post-processing apparatus.
US08784640B2 Amperometric electrochemical sensor and method for manufacturing same
An amperometric electrochemical sensor with a fixed potential used in a probe for measuring the content of an oxidation reduction substance dissolved in a liquid, in particular the chlorine content. The sensor (1) includes an insulating substrate (2), a set of electrodes consisting of a working electrode (3), an auxiliary electrode (4) and a reference electrode, at least one of the working electrode (3) and auxiliary electrode (4) being configured on the insulating substrate (2). At least one of the working electrode (3) and auxiliary electrode (4) is covered with an insulating layer (8), the insulating layer (8) including at least one opening exposing at least one of the working electrode (3) and auxiliary electrode (4).
US08784628B2 E-coating method for archery bow components
An archery bow is provided including an archery component such as a cable guard and/or cable guide that includes an e-coat film to minimize wear abrasion on a cable, bowstring or other element. A metal surface of an archery component optionally can be immersed in a bath of charged coating particles, and the metal surface can be caused to have an electrical charge. The charged coating particles can be electrodeposited on the metal surface to provide a coating.
US08784627B2 Graft copolymers, their preparation and use in capillary electrophoresis
The invention relates to graft copolymers, their preparation, and compositions, such as electrophoresis separation media, containing the same; also to ultra-high molecular weight poly(N,N-dimethylacrylamide) (“poly(DMA)”) polymers, their preparation, and compositions, such as electrophoresis separation media, containing the same; and more particularly to supports, such as capillaries, containing these polymers and methods for separating biomolecules, especially polynucleotides, using capillary electrophoresis. The graft copolymers can be prepared by, e.g., grafting polyacrylamide units onto a poly(DMA) backbone. Separation media comprising such graft copolymers or ultra-high molecular weight poly(DMA) polymers yield superior performance in the analysis and separation of biomolecules by capillary electrophoresis.
US08784626B2 Bio-analysis using ball-ended incident and output optical fibers
A detection optics configuration for bio-analysis, in which the direction of incident radiation, the axis of the separation channel, and the direction of collection of the output radiation are coplanar at the detection zone. The detection configuration incorporates ball-end optical fibers to direct incident radiation at and collection of output radiation from the detection zone. The detection optics configuration may be implemented in an improved bio-separation instrument, in particular a capillary electrophoresis instrument.
US08784625B2 Sensor element containing a sealing element for a functional component
A sensor element having a layered construction and configured to detect a physical property of a gas or a liquid includes a functional component situated in the interior, which functional component is connected electrically to a conductor element, which conductor element extends up to the outer surface or up into the surroundings of the sensor element. The sensor element has at least one sealing element which adjoins the functional component and/or the conductor element. The conductor element and the at least one sealing element are configured to be gas-tight at least regionally in the interior of the sensor element and are situated in such a way that the functional component is separated gas-tight from the surroundings of the sensor element.
US08784620B2 Method of operating a diaphragm electrolytic cell
Described is a method for improving the operation of an electrolytic cell having an anolyte compartment, a catholyte compartment and a synthetic diaphragm separating the compartments, wherein liquid anolyte is introduced into the anolyte compartment and flows through the diaphragm into the catholyte compartment, which method involves introducing particulate material comprising halocarbon polymer short fiber, e.g., fluorocarbon polymer short fiber, into the anolyte compartment in amounts sufficient to lower the flow of liquid anolyte through the diaphragm into the catholyte compartment. In the case of an electrolytic cell wherein aqueous alkali metal chloride, e.g., sodium chloride, anolyte is introduced continuously into the anolyte compartment, thereby to produce a catholyte liquor containing alkali metal hydroxide and hypochlorite ion, the foregoing method is useful for decreasing the concentration of hypochlorite ion in the catholyte liquor and oftentimes increasing the concentration of alkali metal hydroxide in the catholyte liquor. Also describes adding at least one member chosen from halocarbon polymer microfibril, halocarbon polymer fiber, clay mineral, oxides and/or hydroxides of alkaline earth metals, and zirconium oxide/hydroxide in conjunction with the halocarbon polymer short fiber to the anolyte compartment, e.g., while the cell is operating.
US08784618B2 Working electrode design for electrochemical processing of electronic components
An electroplating apparatus is provided that includes a plating tank for containing a plating electrolyte. A counter electrode, e.g., anode, is present in a first portion of the plating tank. A cathode system is present in a second portion of the plating tank. The cathode system includes a working electrode and a thief electrode. The thief electrode is present between the working electrode and the counter electrode. The thief electrode includes an exterior face that is in contact with the plating electrolyte that is offset from the plating surface of the working electrode. In one embodiment, the thief electrode overlaps a portion of the working electrode about the perimeter of the working electrode. In one embodiment, a method is provided of using the aforementioned electroplating apparatus that provides increased uniformity in the plating thickness.
US08784612B2 Storage stable solutions of optical brighteners
The instant invention relates to storage stable solutions of optical brighteners based on certain salt forms of anilino-substituted bistriazinyl derivatives of 4,4′-diaminostilbene-2,2′-disulphonic acid and of organic acids which do not need extra solubilizing additives.
US08784608B2 Methods for beating pulp, methods for treating process waters, and methods for producing pulp and paper
The first invention aims to provide a method for preparing stiffer bulky pulp at a freeness level comparable to that obtained by mechanical treatments to improve the bulkiness of product paper by searching for a method capable of adjusting freeness while suppressing damage to pulp fibers and internal fibrillation in a process for producing pulp. The second invention aims to strip contaminants deposited on pulp fibers and/or inorganic particles to reduce adhesion of the contaminants and decrease microorganisms in a treatment of process water containing long pulp fiber fractions used in a process for producing pulp and paper, thereby clarifying process water and thus preparing high-quality pulp and paper.According to the first invention, cavitation is generated in a pulp suspension preferably by a liquid jet and the resulting fine bubbles are introduced into the pulp suspension to adjust the pulp suspension to a desired freeness by means of the impact force induced by collapse of the fine bubbles in a process for producing pulp. According to the second invention, process water containing 50% by weight or less, based on total solids, of long pulp fiber fractions used in a process for producing pulp and/or paper is treated by cavitation generated by a liquid jet and then returned to the process for producing pulp and/or paper and reused.
US08784607B2 Process for the production of bleached wood particles and pale to white wood-base materials
The present invention relates to a process for the production of bleached wood particles and a process for the production of pale to white wood-base materials which are produced from the bleached wood particles.
US08784604B2 Method and apparatus for out-of-autoclave adhesive shear bonding of structures
The shear bonding method is configured to facilitate bonding of structures in an out-of-autoclave environment. The shear bonding method includes bonding a plurality of frame members to the interior of a tapered tailboom. The frames are located on a bayonet type tool. An adhesive pack is applied to each frame. The bayonet type tool is inserted into the tailboom until the adhesive packs come into contact with the interior walls of the tailboom. Conductive heating tiles are applied to the tailboom. The conductive heating tiles are controlled to achieve and maintain viscosity of the adhesive packs. During this period the bayonet tool is actuated so that the frames are translated in relation to the tailboom. The heating tiles are then controlled to achieve and maintain the adhesive at a requisite curing temperature.
US08784603B2 Actuator device including nanoscale fiber films
A method for making an actuator capable of dry actuation is provided. The method includes providing a first nanoscale fiber film, providing a second nanoscale fiber film, positioning a solid polymer electrolyte at least partially between and adjacent to the first nanoscale fiber film and the second nanoscale fiber film, and then affixing the solid polymer electrolyte to the first nanoscale fiber film and the second nanoscale fiber film. The nanoscale fiber films may be buckypapers, made of carbon nanotubes. The actuator is capable of dry actuation.
US08784601B1 Applying polyester onto metal substrate
The present invention is a laminating process which is directed toward economical production methods for scalable amounts of production which develop properties suitable for a broad based product line. In particular, the product is capable of important key components of commercial properties such as adhesion, scratch resistance, chemical inertness, and bending without failure.
US08784600B2 Method for adhering glass
A method for adhering glass including cleaning ceramic printed glass using a first solution containing dodecylbenzenesulfonic acid, p-toluenesulfonic acid, and a solvent, and cleaning the glass using a second solution containing an alkoxysilane compound. Thereafter, a glass primer is applied to the glass, an adhesive is applied, and the glass is adhered to an adherend. The first solution includes not less than 0.1 mass % and not more than 10 mass % of the dodecylbenzenesulfonic acid, and not less than 0.01 mass % and not more than 5 mass % of the p-toluenesulfonic acid, per 100 mass % of the solvent.
US08784599B2 Laser induced thermal imaging apparatus and method of manufacturing organic light emitting display device using the same
A laser induced thermal imaging (LITI) apparatus includes a stage configured to support an acceptor substrate and a supporting portion configured to support a donor film and to move the donor film up and down relative to the stage so as to adjust a distance between the acceptor substrate and the donor film. The donor film includes a thin film to be disposed on the acceptor substrate. The stage includes a discharging outlet through which gas between the acceptor substrate and the donor film is discharged to the outside. The LITI apparatus may be used to laminate a film on an acceptor substrate including an organic light emitting display device.
US08784597B2 Method for reinforcing a glass of touch panel and reinforcement structure thereof
The present invention provides a method for reinforcing a glass of a touch panel and a reinforcement structure thereof. The method provides at least one protective film and at least one glass substrate. One side of the glass substrate is adhered to one side of the protective film. The glass substrate adhered with the protective film is dipped in an adhesive reservoir. The glass substrate adhered with the protective film is taken out of the adhesive reservoir. After the adhesive is hardened, a reinforcement layer is formed on the other side and the periphery of the glass substrate. The present invention makes the surface of the glass to be more flat with an increased strength.
US08784596B2 Method for making and joining composite sandwich shell edge joint
A method for joining fittings to a composite sandwich shell edge includes laying up an inner facesheet and positioning a wrapped flute mandrel on top; applying a layer of adhesive on the inner facesheet and positioning spacer-supported fittings on top; applying adhesive over the co-bonded fittings and laying up an outer facesheet forming an assembly; curing the assembly under heat and pressure; removing the fittings by first collapsing the spacers and removing the flute mandrel; placing an adhesive layer on the fittings with collapsible spacers inserted therein; reinserting the fittings between the inner and outer facesheets and effecting bonding and curing; and removing the spacers from the fittings by collapsing the spacers.
US08784593B2 Method for manufacturing absorptive article
A method for manufacturing an absorbent article includes joining, one longitudinal end portion of a main absorbent body base material to a back-side band base material and another longitudinal end portion of the absorbent body base material to the abdominal-side band base material, folding the main absorbent body base material and overlapping the back-side band base material with the abdominal-side band base material, temporarily joining the overlapped back-side band base material and abdominal-side band base material cutting the temporarily joined back-side band base material and abdominal-side band base material and forming a back-side band base material piece and an abdominal-side band base material piece, and transporting the back-side band base material piece, the abdominal-side band base material piece and the main absorbent body base material in a transport direction with the back-side band base material piece and the abdominal-side band base material piece in a temporarily joined state.