Document Document Title
US08742593B2 Electrical connection for multichip modules
A semiconductor chip is provided. The semiconductor chip includes a semiconductor substrate, a circuit on the substrate, an insulating layer formed on the circuit, and a plurality of electrically floating conductor lines formed on the insulating layer, at a major surface of the semiconductor chip.
US08742586B2 Stacked multilayer structure and manufacturing method thereof
A stacked multilayer structure according to an embodiment of the present invention comprises: a stacked layer part including a plurality of conducting layers and a plurality of insulating layers, said plurality of insulating layers being stacked alternately with each layer of said plurality of conducting layers, one of said plurality of insulating layers being a topmost layer among said plurality of conducting layers and said plurality of insulating layers; and a plurality of contacts, each contact of said plurality of contacts being formed from said topmost layer and each contact of said plurality of contacts being in contact with a respective conducting layer of said plurality of conducting layers, a side surface of each of said plurality of contacts being insulated from said plurality of conducting layers via an insulating film.
US08742585B2 Semiconductor device having a plurality of pads of low diffusible material formed in a substrate
A semiconductor device with a connection pad in a substrate, the connection pad having an exposed surface made of a metallic material that diffuses less readily into a dielectric layer than does a metal of a wiring layer connected thereto.
US08742583B2 Seal ring in an integrated circuit die
The formation of a seal ring in a semiconductor integrated circuit (IC) die is described. Through-silicon vias (TSVs) are typically formed in a semiconductor IC die to facilitate the formation of a three dimensional (3D) stacking die structure. The TSVs may be utilized to provide electrical connections between components in different dies of the 3D stacking die structure. A seal ring is formed in the inter-metal dielectric (IMD) layers of an IC die, enclosing an active circuit region. The real ring is formed prior to the formation of the TSVs, preventing moistures or other undesired chemical agents from diffusing into the active circuit region during the subsequent processes of forming TSVs.
US08742582B2 Solder interconnect on IC chip
A semiconductor chip suited for being electrically connected to a circuit element includes a line and a bump. The bump is connected to the line and is adapted to be electrically connected to the line. A plane that is horizontal to an active surface of the semiconductor chip is defined. The area that the connection region of the line and the bump is projected on the plane is larger than 30,000 square microns or has an extension distance larger than 500 microns.
US08742572B2 Microelectronic devices and methods for manufacturing microelectronic devices
Microelectronic devices and methods for manufacturing microelectronic devices are disclosed herein. An embodiment of one such method includes forming a plurality of through holes in a substrate with the through holes arranged in arrays, and attaching a plurality of singulated microelectronic dies to the substrate with an active side of the individual dies facing toward the substrate and with a plurality of terminals on the active side of the individual dies aligned with corresponding holes in the substrate. The singulated dies are attached to the substrate after forming the holes in the substrate.
US08742564B2 Chip package and method for forming the same
An embodiment of the invention provides a chip package which includes a substrate having a first surface and a second surface; a conducting pad structure located on the first surface; a dielectric layer located on the first surface of the substrate and the conducting pad structure, wherein the dielectric layer has an opening exposing a portion of the conducting pad structure; and a cap layer located on the dielectric layer and filled into the opening.
US08742555B2 Lead frame having a flag with in-plane and out-of-plane mold locking features
A semiconductor device lead frame having enhanced mold locking features is provided. The lead frame has a flag with bendable edge features along the edge of the flag. Each edge feature is shaped to resist movement against encapsulating mold material in a plane of the edge feature. By bending a portion of the edge feature, improved mold locking of the flag is provided in multiple planes.
US08742551B2 Semiconductor package and method of manufacturing the same
A semiconductor package including: a lead frame including a chip attachment unit and a lead unit; a semiconductor chip that is mounted on the chip attachment unit of the lead frame; a wire that electrically connects the semiconductor chip to the lead unit; an insulation layer formed in the lead frame under the chip attachment unit; and an encapsulant that seals an upper portion of the lead frame, the semiconductor chip, and the wire, wherein the lead unit does not protrude to the outside of the encapsulant.
US08742549B2 Shallow trench isolation structure
A semiconductor structure includes: a substrate with at least a trench therein, wherein the trench is filled with an insulation layer; a first polysilicon layer disposed on the insulation layer and covering at least two opposite borders of a top surface of the insulation layer; a second polysilicon layer disposed above the first polysilicon layer and the substrate; and a dielectric layer disposed between the first and second polysilicon layers, wherein the first and second polysilicon layers are respectively shaped as first and second strips.
US08742547B2 Semiconductor wafer and its manufacture method, and semiconductor chip
A semiconductor wafer includes: a first semiconductor chip area formed with a semiconductor element; a second semiconductor chip area formed with a semiconductor element; and a scribe area sandwiched between the first and second semiconductor chip areas; wherein: the first semiconductor chip area includes a first metal ring surrounding the semiconductor element formed in the first semiconductor chip area; and the metal ring is constituted of a plurality of metal layers including a lower metal layer and an upper metal layer superposed upon the lower metal layer, and the upper metal layer is superposed upon the lower metal layer in such a manner that an outer side wall of the upper metal layer is flush with the outer side wall of the lower metal layer or is at an inner position of the first semiconductor chip area relative to the outer side wall of the lower metal layer.
US08742539B2 Semiconductor component and method for producing a semiconductor component
One aspect of the invention relates to a semiconductor component with a semiconductor body with a top side and with a bottom side. A first coil that is monolithically integrated with the semiconductor body is arranged distant from the bottom side and comprises N first windings, wherein N≧1. The first coil has a first coil axis that extends in a direction different from a surface normal of the bottom side.
US08742537B2 Semiconductor device and method of manufacturing the same
Disclosed is a semiconductor device including: a semiconductor substrate; first and second element isolating trenches that are formed in one main surface of the semiconductor substrate separately from each other; a first insulating material that is formed within the first element isolating trench; a plurality of first element formation regions that are surrounded by the first element isolating trench; first semiconductor elements that are respectively formed in the first element formation regions; a second insulating material that is formed within the second element isolating trench; a second element formation region that is surrounded by the second element isolating trench; a second semiconductor element that is formed in the second element formation region; and a stress relaxation structure that is formed between the first element isolating trench and the second element isolating trench.
US08742535B2 Integration of shallow trench isolation and through-substrate vias into integrated circuit designs
A method of manufacturing an IC, comprising providing a substrate having a first side and a second opposite side, forming a STI opening in the first side of the substrate and forming a partial TSV opening in the first side of the substrate and extending the partial TSV opening. The extended partial TSV opening is deeper into the substrate than the STI opening. The method also comprises filling the STI opening with a first solid material and filling the extended partial TSV opening with a second solid material. Neither the STI opening, the partial TSV opening, nor the extended partial TSV opening penetrate an outer surface of the second side of the substrate. At least either: the STI opening and the partial TSV opening are formed simultaneously, or, the STI opening and the extended partial TSV opening are filled simultaneously.
US08742531B2 Electrical devices including dendritic metal electrodes
The present invention relates generally to electrical devices. The present invention relates more particularly to electrical devices including dendritic metal electrodes. One aspect of the present invention is an electrical device comprising a first electrode comprising at least one dendritic metal structure; a second electrode; and an electrically active structure disposed between the dendritic metal structure and the second electrode.
US08742530B2 Conduction element, manufacturing method thereof, wiring element, information input device, display device, and electronic apparatus
A conduction element includes a substrate which has a first wave surface and a second wave surface, and a laminate film which is formed on the first wave surface and where two or more layers are laminated, where the laminate film forms a conduction pattern, and the first wave surface and the second wave surface satisfy a relationship below. 0≦(Am1/λm1)<(Am2/λm2)≦1.8 (Here, Am1: average width of vibration in the first wave surface, Am2: average width of vibration in the second wave surface, λm1: average wavelength of the first wave surface, λm2: average wavelength of the second wave surface).
US08742527B2 Solid state imaging device, solid state imaging element, portable information terminal device and method for manufacturing the solid state imaging element
According to one embodiment, a solid state imaging device includes a sensor substrate curved such that an upper face having a plurality of pixels formed is recessed and an imaging lens provided on the upper face side.
US08742526B2 Photoelectric conversion device
A photoelectric conversion device including a substrate, a photoelectric conversion element including a first electrode, a second electrode and an organic compound layer and a sealing member that are disposed in this order. When a cross section of the photoelectric conversion device in a thickness direction is observed with the sealing member being placed at an upper side, a bonding member seals the organic compound layer at an outside thereof. An output electrode on the sealing member has a protrusion. A side conductive portion is electrically connected with the protrusion in an up-and-down direction. A substrate conductive member electrically connected with the first electrode and the second electrode extends to an outside of the bonding member. An electrical connecting member electrically connects the side conductive portion to the substrate conductive member at a further outside of the bonding member.
US08742525B2 Solid-state imaging device, method of manufacturing solid-state imaging device, and electronic apparatus
A solid-state imaging device includes pixels each having a photoelectric conversion element for converting incident light to an electric signal, color filters associated with the pixels and having a plurality of color filter components, microlenses converging the incident light through the color filters to the photoelectric conversion elements, a light shielding film disposed between the color filter components of the color filters, and a nonplanarized adhesive film provided between the color filters and the light shielding film.
US08742522B2 Method of making a semiconductor radiation detector
A method of making a semiconductor radiation detector wherein the metal layers which serve as the cathode and anode electrodes are recessed from the designated prospective dice lines which define the total upper and lower surface areas for each detector such that the dicing blade will not directly engage the metal during dicing and therefore prevent metal from intruding upon (smearing) the vertical side walls of the detector substrate.
US08742520B2 Three axis magnetic sensor device and method
A method and structure for a three-axis magnetic field sensing device is provided. The device includes a substrate, an IC layer, and preferably three magnetic field sensors coupled to the IC layer. A nickel-iron magnetic field concentrator is also provided.
US08742519B2 Magnetic storage element and magnetic memory
Disclosed herein is a magnetic storage element including: a reference layer configured to have a magnetization direction fixed to a predetermined direction; a recording layer configured to have a magnetization direction that changes due to spin injection in a direction corresponding to recording information; an intermediate layer configured to separate the recording layer from the reference layer; and a heat generator configured to heat the recording layer. A material of the recording layer is such a magnetic material that magnetization at 150° C. is at least 50% of magnetization at a room temperature and magnetization at a temperature in a range from 150° C. to 200° C. is in a range from 10% to 80% of magnetization at a room temperature.
US08742516B2 HF-MEMS switch
A high frequency-MEMS switch with a bendable switching element, whose one end is placed on a high resistivity substrate provided with an insulator, furthermore with a contact electrode to supply charge carriers to the substrate, wherein an electrical field can be produced to create an electrostatic bending force on the switching element between the switching element and the substrate, wherein at least one implantation zone is formed in the substrate, essentially directly beneath the insulator, the implantation zone is contacted with the contact electrode, which is located above the insulator, through an opening in the insulator, and also has ohmic contact with the substrate.
US08742505B2 Apparatus comprising a first transistor including a channel in a fin and a second transistor including a channel in a fin
One or more embodiments relate to an apparatus comprising: a first transistor including a channel in a fin; and a second transistor including a channel in a fin, the channel of the first transistor being doped with a first dopant of a first polarity and counter-doped with a second dopant of a second polarity opposite to the first polarity, a concentration of the first dopant being approximately equal to a concentration of the second dopant, wherein the first transistor and the second transistor are of a same conductivity type.
US08742501B2 Power semiconductor devices and methods for manufacturing the same
A power semiconductor device that realizes high-speed turnoff and soft switching at the same time has an n-type main semiconductor layer that includes lightly doped n-type semiconductor layers and extremely lightly doped n-type semiconductor layers arranged alternately and repeatedly between a p-type channel layer and an n+-type field stop layer, in a direction parallel to the first major surface of the n-type main semiconductor layer. A substrate used for manufacturing the semiconductor device is fabricated by forming trenches in an n-type main semiconductor layer 1 and performing ion implantation and subsequent heat treatment to form an n+-type field stop layer in the bottom of the trenches. The trenches are then filled with a semiconductor doped more lightly than the n-type main semiconductor layer for forming extremely lightly doped n-type semiconductor layers. The manufacturing method is applicable with variations to various power semiconductor devices such as IGBT's, MOSFET's and PIN diodes.
US08742500B2 Semiconductor device
A semiconductor device is disclosed wherein a peripheral region with a high breakdown voltage and high robustness against induced surface charge is manufactured using a process with high mass productivity. The device has n-type drift region and p-type partition region of layer-shape deposited in a vertical direction to one main surface of n-type semiconductor substrate with high impurity concentration form as drift layer, alternately adjacent parallel pn layers in a direction along one main surface. Active region through which current flows and peripheral region enclosing the active region include parallel pn layers. P-type partition region has impurity concentration distribution where concentration decreases from surface toward substrate side, n-type surface region disposed on parallel pn layers in peripheral region, p-type guard rings disposed separately from each other on n-type surface region, and field plate disposed on inner and outer circumferential sides of p-type guard rings, and electrically connected.
US08742499B2 Semiconductor device and manufacturing method thereof
In a semiconductor chip in which LDMOSFET elements for power amplifier circuits used for a power amplifier module are formed, a source bump electrode is disposed on an LDMOSFET formation region in which a plurality of source regions, a plurality of drain regions and a plurality of gate electrodes for the LDMOSFET elements are formed. The source bump electrode is formed on a source pad mainly made of aluminum via a source conductor layer which is thicker than the source pad and mainly made of copper. No resin film is interposed between the source bump electrode and the source conductor layer.
US08742498B2 High voltage semiconductor device and fabricating method thereof
A method for fabricating a high voltage semiconductor device is provided. Firstly, a substrate is provided, wherein the substrate has a first active zone and a second active zone. Then, a first ion implantation process is performed to dope the substrate by a first mask layer, thereby forming a first-polarity doped region at the two ends of the first active zone and a periphery of the second active zone. After the first mask layer is removed, a second ion implantation process is performed to dope the substrate by a second mask layer, thereby forming a second-polarity doped region at the two ends of the second active zone and a periphery of the first active zone. After the second mask layer is removed, a first gate conductor structure and a second gate conductor structure are formed over the middle segments of the first active zone and the second active zone, respectively.
US08742496B2 Sonos memory cells having non-uniform tunnel oxide and methods for fabricating same
Methods for forming a memory cell are disclosed. A method includes forming a source-drain structure in a semiconductor substrate where the source-drain structure includes a rounded top surface and sidewall surfaces. An oxide layer is formed on the top and sidewall surfaces of the source-drain structure. The thickness of the portion of the oxide layer that is formed on the top surface of the source-drain structure is greater than the thickness of the portion of the oxide layer that is formed on the sidewall surfaces of the source-drain structure.
US08742495B2 High-voltage vertical transistor with a varied width silicon pillar
In one embodiment, a vertical HVFET includes a pillar of semiconductor material a pillar of semiconductor material arranged in a loop layout having at least two substantially parallel and substantially linear fillet sections each having a first width, and at least two rounded sections, the rounded sections having a second width narrower than the first width, a source region of a first conductivity type being disposed at or near a top surface of the pillar, and a body region of a second conductivity type being disposed in the pillar beneath the source region. First and second dielectric regions are respectively disposed on opposite sides of the pillar, the first dielectric region being laterally surrounded by the pillar, and the second dielectric region laterally surrounding the pillar. First and second field plates are respectively disposed in the first and second dielectric regions.
US08742491B2 FinFET process compatible native transistor
Provided is a top-channel only finFET device. The devices described herein may provide a native device that is compatible with a finFET process flow. A gate may be formed on the top of a fin providing the channel region of the device. In an embodiment, the gate is provided only on one side of the channel, for example, on the top of the fin. The sidewalls of the fin including channel may abut an isolation structure. In an embodiment, isolation structures are formed between the fins to provide a planar surface for the formation of a gate.
US08742490B2 Vertical power transistor die packages and associated methods of manufacturing
The present technology is directed generally to a semiconductor device. In one embodiment, the semiconductor device includes a first vertical transistor and a second vertical transistor, and the first vertical transistor is stacked on top of the second vertical transistor. The first vertical transistor is mounted on a lead frame with the source electrode of the first vertical transistor coupled to the lead frame. The second vertical transistor is stacked on the first vertical transistor with the source electrode of the second vertical transistor coupled to the drain electrode of the first vertical transistor.
US08742487B2 Nonvolatile semiconductor memory device provided with charge storage layer in memory cell
A nonvolatile semiconductor memory device includes a semiconductor substrate, a first insulation layer formed on the semiconductor substrate, a charge storage layer formed on the first insulation layer, a second insulation layer formed on the charge storage layer and including a first high dielectric insulating film which has a higher relative permittivity than a silicon nitride film and a second high dielectric insulating film which has a higher relative permittivity than a silicon nitride film, the first and second high dielectric insulating films being structured so that a silicon oxide film is interposed between them, a control electrode formed on the second insulation layer, a first portion formed between the charge storage layer and the second insulation layer and containing silicon and nitrogen, and a second portion containing silicon and oxygen and located between the charge storage layer and the second insulation layer.
US08742486B2 Flash memory cells having trenched storage elements
An embodiment of the present invention is directed to a memory cell. The memory cell includes a first trench formed in a semiconductor substrate and a second trench formed in said semiconductor substrate adjacent to said first trench. The first trench and the second trench each define a first side wall and a second sidewall respectively. The memory cell further includes a first storage element formed on the first sidewall of the first trench and a second storage element formed on the second sidewall of the second trench.
US08742479B2 Semiconductor device and method of manufacturing the same
A transistor is formed on a semiconductor substrate, and thereafter a first insulating film is formed. Subsequently, a ferroelectric capacitor is formed on the first insulating film, and then a second insulating film is formed on the ferroelectric capacitor. Thereafter, the upper surface of the second insulating film is planarized. Subsequently, a contact hole which reaches one of impurity regions of the transistor is formed, and thus a plug is formed by embedding a conductor in the contact hole. Thereafter, a hydrogen barrier layer is formed of aluminum oxide or the like. Then, a third insulating film is formed on the hydrogen barrier layer. Subsequently, contact holes which are connected to the ferroelectric capacitor and the plug are formed. Thereafter, a conductor is embedded in the contact holes, and thus interconnections are formed.
US08742478B2 Graphene transistor having air gap, hybrid transistor having the same, and methods of fabricating the same
A graphene transistor includes: a gate electrode on a substrate; a gate insulating layer on the gate electrode; a graphene channel on the gate insulating layer; a source electrode and a drain electrode on the graphene channel, the source and drain electrode being separate from each other; and a cover that covers upper surfaces of the source electrode and the drain electrode and forms an air gap above the graphene channel between the source electrode and the drain electrode.
US08742473B2 Semiconductor devices having lightly doped channel impurity regions
Semiconductor devices are provided including a gate across an active region of a substrate; a source region and a drain region in the active region on either side of the gate and spaced apart from each other; a main channel impurity region in the active region between the source and drain regions and having a first channel impurity concentration; and a lightly doped channel impurity region in the active region adjacent to the drain region. The lightly doped channel impurity region has the same conductivity type as the main channel impurity region and a second channel impurity concentration, lower than the first channel impurity concentration. The lightly doped channel impurity region and the main channel impurity region contain a first element. The lightly doped channel impurity region also contains a second element, which is a different Group element from the first element.
US08742469B2 Active chemically-sensitive sensors with correlated double sampling
Methods and apparatus relating to FET arrays for monitoring chemical and/or biological reactions such as nucleic acid sequencing-by-synthesis reactions. Some methods provided herein relate to improving signal (and also signal to noise ratio) from released hydrogen ions during nucleic acid sequencing reactions.
US08742466B2 Three-dimensional semiconductor device including a mold structure providing gap regions and an interconnection structure including a plurality of interconnection patterns formed in the gap regions
Provided are a three-dimensional semiconductor device and a method of fabricating the same. The three-dimensional semiconductor device may include a mold structure for providing gap regions and an interconnection structure including a plurality of interconnection patterns disposed in the gap regions. The mold structure may include interlayer molds defining upper surfaces and lower surfaces of the interconnection patterns and sidewall molds defining sidewalls of the interconnection patterns below the interlayer molds.
US08742464B2 Power routing in standard cells
An integrated circuit created from a cell library of compact cells. The cell library includes cells having a metal trace routed along the boundary of the cells for carrying a power supply voltage. The cells also include another metal trace routed along the interior of the cells for carrying another power supply voltage. A cell pin carrying an input signal or output signal of the cell is located outside of the region between the two power rails. By routing the power supply voltages and cell pins of the cell in this manner, the integrated circuit created from the cell is extremely compact while still complying with various design rules.
US08742462B2 Integrated circuit including cross-coupled transistors having gate electrodes formed within gate level feature layout channels with gate contact position specifications
First and second PMOS transistors are defined over first and second p-type diffusion regions. First and second NMOS transistors are defined over first and second n-type diffusion regions. Each diffusion region is electrically connected to a common node. Gate electrodes are formed from conductive features that are each defined within any one gate level channel that is uniquely associated with and defined along one of a number of parallel gate electrode tracks. At least a portion of each of the first and second p-type diffusion regions are formed over a first common line of extent that extends perpendicular to the first parallel direction. The first and second n-type diffusion regions are formed in a spaced apart manner relative to the first parallel direction, such that no single line of extent that extends across the substrate perpendicular to the first parallel direction intersects both the first and second n-type diffusion regions.
US08742460B2 Transistors with isolation regions
A transistor device is described that includes a source, a gate, a drain, a semiconductor material which includes a gate region between the source and the drain, a plurality of channel access regions in the semiconductor material on either side of the gate, a channel in the semiconductor material having an effective width in the gate region and in the channel access regions, and an isolation region in the gate region. The isolation region serves to reduce the effective width of the channel in the gate region without substantially reducing the effective width of the channel in the access regions. Alternatively, the isolation region can be configured to collect holes that are generated in the transistor device. The isolation region may simultaneously achieve both of these functions.
US08742454B2 Semiconductor device
In a semiconductor device having a semiconductor substrate on which a diode and an IGBT are formed, a cathode region of the diode and a collector region of the IGBT are formed in a range exposed to one surface of the semiconductor substrate. On the surface, a first conductor layer that is in contact with the cathode region, and a second conductor layer that is in contact with the collector region are formed. The work function of the second conductor layer is larger than the work function of the first conductor layer.
US08742447B2 Light emitting device, light emitting device package and lighting system
Disclosed are a light emitting device, a light emitting device package, and a lighting system. The light emitting device includes a light emitting structure including a first conductive semiconductor layer, an active layer and a second conductive semiconductor layer; a substrate over the light emitting structure; a first reflective layer having a plurality of dielectric layers including a first dielectric layer having a first refractive index over the substrate, and a second dielectric layer having a second refractive index different from the first refractive index over the first dielectric layer; and a second reflective layer over the first reflective layer, the second reflective layer having a refractive index lower than the refractive index of each dielectric layer of the first reflective layer.
US08742444B2 Semiconductor light-emitting device
A semiconductor light-emitting device (A) having a simple configuration whereby it is possible to easily and accurately confirm whether or not ultraviolet light is being emitted, the semiconductor light-emitting device comprising: a semiconductor light-emitting element (1) for emitting ultraviolet light in an ultraviolet or deep ultraviolet region; a cap part (6) having a through-hole (63) in the top part through which ultraviolet light passes and encircling the semiconductor light-emitting element (1); a translucent cover (7) for transmitting ultraviolet light, the translucent cover being disposed so as to hermetically close up the through-hole (63); and a UV-excited phosphor (8) which is excited by ultraviolet light and which emits visible light, the UV-excited phosphor being disposed inside the cap part (6).
US08742443B2 Light emitting diode epitaxial structure and manufacturing method of the same
An LED epitaxial structure includes a substrate, a buffer layer, a functional layer and a light generating layer. The buffer layer is located on a top surface of the substrate. The functional layer includes a plurality of high-temperature epitaxial layers and low-temperature epitaxial layers alternatively arranged between the buffer layer and light generating layer. A textured structure is formed in the low-temperature epitaxial layer. A SiO2 layer including a plurality of convexes is located on the textured structure to increase light extraction efficiency of the LED epitaxial structure. A manufacturing method of the LED epitaxial structure is also disclosed.
US08742442B2 Method for patterning an epitaxial substrate, a light emitting diode and a method for forming a light emitting diode
A method for patterning an epitaxial substrate includes: (a) forming an etch mask layer over an epitaxial substrate, and patterning the etch mask layer using a patterned cover mask layer to form the etch mask layer into a plurality of spaced apart mask patterns; and (b) etching the epitaxial substrate that is exposed from the mask patterns, and removing the mask patterns such that the epitaxial substrate is formed with a plurality of spaced apart substrate patterns.
US08742440B2 Nitride semiconductor light-emitting element and method for producing same
Disclosed is a nitride semiconductor light-emitting element comprising a p-type nitride semiconductor layer 1, a p-type nitride semiconductor layer 2, and a p-type nitride semiconductor layer 3 placed in order above a nitride semiconductor active layer, wherein the p-type nitride semiconductor layer 1 and p-type nitride semiconductor layer 2 each contain Al, the average Al composition of the p-type nitride semiconductor layer 1 is equivalent to the average Al composition of the p-type nitride semiconductor layer 2, the p-type nitride semiconductor layer 3 has a smaller band gap than the p-type nitride semiconductor layer 2, the p-type impurity concentration of the p-type nitride semiconductor layer 2 and the p-type impurity concentration of the p-type nitride semiconductor layer 3 are both lower than the p-type impurity concentration of the p-type nitride semiconductor layer 1, and a method for producing same.
US08742439B2 Nitride based light emitting device
A nitride based light emitting device is disclosed. More particularly, a nitride based light emitting device capable of improving light emitting efficiency and reliability thereof is disclosed. The nitride based light emitting device includes a first conductive semiconductor layer connected to a first electrode, a second conductive semiconductor layer connected to a second electrode, an active layer located between the first conductive semiconductor layer and the second conductive semiconductor layer and having a quantum well structure, a first insertion layer located in at least one of a boundary between the first conductive semiconductor layer and the active layer and a boundary between the second conductive semiconductor layer and the active layer, and a second insertion layer located adjacent to the first insertion.
US08742433B2 Semiconductor light emitting apparatus
A light emitting apparatus with a combination of a plurality of LED chips and a phosphor layer is provided and can be configured to significantly reduce variations in chromaticity and luminance. The plurality of semiconductor light emitting devices (LED chips) are disposed with a gap therebetween, and the phosphor layer is formed on the upper surface thereof to bridge over the gaps between the LED chips. The phosphor layer may be uniform in thickness, but can be less in thickness over the gaps between the LED chips than on the upper surface of the LED chips. The phosphor layer can be continuously formed on the upper surface of the array of the chips with no phosphor layer present in between the chips. This configuration allows for reducing variations in luminance and chromaticity which may result from the gaps or the phosphor layer present in between the gaps.
US08742430B2 Organic light emitting element
An object of the present invention is to provide an organic light emitting element where light emitted from the light emitting layer is efficiently emitted to the outside, and thus, the efficiency of light emission is higher. The present invention provides an organic light emitting element where a first reflective electrode 22, an electron transport layer 23, a light emitting layer 24, a hole transport layer 25, a hole injection layer 26 and a second transparent electrode 27 are formed on a glass substrate 21, and a light extraction layer 28 having an average index of refraction of 1.4 made of titanium particles having an index of refraction of 2.6 and an average particle diameter of 150 nm and silica sol.
US08742427B2 Semiconductor element
A semiconductor element according to the present invention can perform both a transistor operation and a diode operation via its channel layer. If the potential Vgs of its gate electrode 165 with respect to that of its source electrode 150 is 0 volts, then a depletion layer with a thickness Dc, which has been depleted entirely in the thickness direction, is formed in at least a part of the channel layer 150 due to the presence of a pn junction between a portion of its body region 130 and the channel layer 150, and another depletion layer that has a thickness Db as measured from the junction surface of the pn junction is formed in that portion of the body region 130. If the dielectric constant of the wide bandgap semiconductor is identified by ∈s, the dielectric constant and the thickness of the insulating film 160 are identified by ∈i and Di, respectively, the sum of Dc and Db is identified by Ds, and the absolute value of the turn-on voltage of the diode is identified by Vf0, then Ds
US08742425B2 Thin film transistor array substrate, organic light-emitting display device comprising the same, and method of manufacturing the same
A thin film transistor array substrate includes a thin film transistor including a gate electrode, an active layer, and source and drain electrodes, a pixel electrode on a same layer as the gate electrode, a lower electrode of a capacitor, the lower electrode being on the same layer as the gate electrode, a first insulating layer on the gate electrode and the lower electrode, a second insulating layer between the active layer and the source and drain electrodes, an upper electrode on the first insulating layer, the upper electrode including a first layer made of a same material as the active layer, and a second layer made of a same material as the source and drain electrodes, and a third insulating layer that covers the source and drain electrodes and the upper electrode and exposes the pixel electrode.
US08742424B2 Shift register and display apparatus
The present invention provides a shift register and a display device, each of which operates stably. The present invention relate to a shift register, comprising a thin-film transistor which includes a source electrode, a drain electrode, and a gate electrode, the thin-film transistor being a bottom gate thin-film transistor which includes a comb-shaped source/drain structure, the gate electrode being provided with at least one of a cut and an opening in at least one of a region overlapping with the source electrode and a region overlapping with the drain electrode.
US08742423B2 Thin-film transistor array and image display device in which thin-film transistor array is used
In a thin-film transistor array according to an embodiment of the present invention, thin-film transistors are disposed in a matrix array, the thin-film transistor including a gate electrode that is formed on a substrate, a gate insulating layer that is formed on the gate electrode, a source electrode that is formed on the gate insulating layer, a pixel electrode that is formed on the gate insulating layer, a drain electrode that is connected to the pixel electrode, and a semiconductor layer that is formed between the source electrode and the drain electrode, the gate electrode is connected to a gate line while the source electrode is connected to a source line, the thin-film transistor is formed within a region of the source line and the thin-film transistor array includes a stripe insulating film such that the source line and the semiconductor layer are covered with the stripe insulating film.
US08742422B2 Semiconductor device and manufacturing method thereof
The semiconductor device includes a driver circuit portion including a driver circuit and a pixel portion including a pixel. The pixel includes a gate electrode layer having a light-transmitting property, a gate insulating layer, a source electrode layer and a drain electrode layer each having a light-transmitting property provided over the gate insulating layer, an oxide semiconductor layer covering top surfaces and side surfaces of the source electrode layer and the drain electrode layer and provided over the gate electrode layer with the gate insulating layer therebetween, a conductive layer provided over part of the oxide semiconductor layer and having a lower resistance than the source electrode layer and the drain electrode layer, and an oxide insulating layer in contact with part of the oxide semiconductor layer.
US08742420B2 Gate driving circuit, display substrate having the same and method of manufacturing the display substrate
A gate driving circuit includes a plurality of stages outputting gate signals to a plurality of gate lines. Each of the stages includes a circuit transistor, a capacitor part, a first connecting electrode and a second connecting electrode. The circuit transistor outputs the gate signal to an output electrode in response to a control signal inputted to a control electrode. The capacitor part is disposed adjacent to the circuit transistor, and includes a first electrode, a second electrode disposed over the first electrode, a third electrode disposed over the second electrode and a fourth electrode disposed over the third electrode. The first connecting electrode electrically connects the control electrode to the first and third electrodes. The second connecting electrode electrically connects the output electrode to the second and fourth electrodes.
US08742416B2 Display panel, method of manufacturing display panel, display device, and electronic apparatus
A display panel includes: gate lines disposed on a first substrate; signal lines extending across the gate lines and including portions, other than portions thereof that extend across the gate lines, disposed on the same surface as the gate lines, the portions that extend across the gate lines being disposed in positions facing the gate lines with an insulating film interposed therebetween; transistors having gate electrodes connected to the gate lines, source electrodes connected to the signal lines and disposed on the insulating film, and drain electrodes disposed on the insulating film; pixel electrodes connected to the drain electrode and disposed on the insulating film; a protective film covering the transistors and the pixel electrodes; and a common electrode disposed on the protective film.
US08742414B2 Composition for an oxide thin film, a preparation method of the composition, a method for forming an oxide thin film using the composition, an electronic device including the oxide thin film, and a semiconductor device including the oxide thin film
Provided are a composition for an oxide thin film, a preparation method of the composition, a method for forming an oxide thin film using the composition, an electronic device including the oxide thin film, and a semiconductor device including the oxide thin film. The composition for the oxide thin film includes a metal precursor and nitric acid-based stabilizer. The metal precursor includes at least one of a metal nitrate, a metal nitride, and hydrates thereof.
US08742412B2 Thin film transistor using an oxide semiconductor and display
A thin film transistor includes a gate electrode, a gate insulation layer, a channel layer, a source electrode, and a drain electrode formed on a substrate, in which: the channel layer contains indium, germanium, and oxygen; and the channel layer has a compositional ratio expressed by In/(In+Ge) of 0.5 or more and 0.97 or less.
US08742411B2 Adhesive film and method of encapsulating organic electrode device using the same
An adhesive film, and a product and method of encapsulating an organic electronic device (OED) using the same are provided. The adhesive film serves to encapsulate the OED and includes a curable hot-melt adhesive layer including a curable resin and a moisture absorbent, and the curable hot-melt adhesive layer includes a first region coming in contact with the OED upon encapsulation of the OED and a second region not coming in contact with the OED. Also, the moisture absorbent is present at contents of 0 to 20% and 80 to 100% in the first and second regions, respectively, based on the total weight of the moisture absorbent in the adhesive layer.
US08742410B2 Fused polycyclic heteroaromatic compound, organic thin film including the compound and electronic device including the organic thin film
A low-molecular-weight fused polycyclic heteroaromatic compound, an organic thin film and an electronic device including the fused polycyclic heteroaromatic compound, include a compact planar structure in which six or more rings are fused together, and thereby exhibits high charge mobility, and furthermore, enables the use of a deposition process or a room-temperature solution process when applied to devices, therefore realizing improved processibility.
US08742406B1 Soft lithography microlens fabrication and array for enhanced light extraction from organic light emitting diodes (OLEDs)
Provided are microlens arrays for use on the substrate of OLEDs to extract more light that is trapped in waveguided modes inside the devices and methods of manufacturing same. Light extraction with microlens arrays is not limited to the light emitting area, but is also efficient in extracting light from the whole microlens patterned area where waveguiding occurs. Large microlens array, compared to the size of the light emitting area, extract more light and result in over 100% enhancement. Such a microlens array is not limited to (O)LEDs of specific emission, configuration, pixel size, or pixel shape. It is suitable for all colors, including white, for microcavity OLEDs, and OLEDs fabricated directly on the (modified) microlens array.
US08742404B2 Organic light emitting display device and manufacturing method thereof
An organic light emitting diode display comprises: a substrate; an active layer formed with a semiconductor material on the substrate; a first insulation layer formed on the semiconductor layer; a pixel electrode formed on the first insulation layer and generated by alternately stacking a plurality of pixel metal layers and a plurality of pixel transparent conductive layers; a gate electrode formed on the first insulation layer and formed in a configuration different from that of the pixel electrode; a second insulation layer formed on the first insulation layer so as to cover the gate electrode with an insulation layer opening for revealing the pixel electrode; a source electrode and a drain electrode respectively formed on the second insulation layer and electrically connected to the active layer; an organic emission layer formed on the pixel electrode; and a common electrode formed on the organic emission layer.
US08742398B2 Quantum dot-fullerene junction based photodetectors
A photodetector includes one or more photodiodes and a signal processing circuit. Each photodiode includes a transparent first electrode, a second electrode, and a heterojunction interposed between the first electrode and the second electrode. Each heterojunction includes a quantum dot layer and a fullerene layer disposed directly on the quantum dot layer. The signal processing circuit is in signal communication each the second electrode. The photodetector may be responsive to wavelengths in the infrared, visible, and/or ultraviolet ranges. The quantum dot layer may be treated with a chemistry that increases the charge carrier mobility of the quantum dot layer.
US08742397B2 Semiconductor light emitting device and method for manufacturing the same
A semiconductor light emitting device includes a first nitride semiconductor layer, a dopant doped semiconductor layer on the first nitride semiconductor layer, an active layer on the dopant doped semiconductor layer, a delta doped layer on the active layer, a superlattice structure on the delta doped layer, an undoped layer on the superlattice layer, a second nitride semiconductor layer including a first n-type dopant, a third nitride semiconductor layer including a second n-type dopant, and a fourth nitride semiconductor layer including a third n-type dopant.
US08742396B2 III nitride epitaxial substrate and deep ultraviolet light emitting device using the same
A III nitride epitaxial substrate which makes it possible to obtain a deep ultraviolet light emitting device with improved light output power is provided. A III nitride epitaxial substrate includes a substrate, an AlN buffer layer, a first superlattice laminate, a second superlattice laminate and a III nitride laminate in this order. The III nitride laminate includes an active layer including an AlαGa1-αN (0.03≦α) layer. The first superlattice laminate includes AlaGa1-aN layers and AlbGa1-bN (0.9
US08742392B2 Bipolar multistate nonvolatile memory
Embodiments generally include a method of forming a nonvolatile memory device that contains a resistive switching memory element that has an improved device switching capacity by using multiple layers of variable resistance layers. In one embodiment, the resistive switching element comprises at least three layers of variable resistance materials to increase the number of logic states. Each variable resistance layer may have an associated high resistance state and an associated low resistance state. As the resistance of each variable resistance layer determines the digital data bit that is stored, the multiple variable resistance layers per memory element allows for additional data storage without the need to further increase the density of nonvolatile memory devices. Typically, resistive switching memory elements may be formed as part of a high-capacity nonvolatile memory integrated circuit, which can be used in various electronic devices, such as digital cameras, mobile telephones, handheld computers, and music players.
US08742391B2 Non-volatile semiconductor memory
A non-volatile semiconductor memory includes a word line extending in a first direction, a first electrode connected to the word line electrically, an ion diffusion layer with connected to the first electrode electrically, a second electrode connected to the ion diffusion layer electrically and formed of a metal to be diffused into the ion diffusion layer when a positive voltage is supplied thereto, and a bit line extending in a second direction perpendicular to the first direction, the bit line connected to the second electrode electrically. The ion diffusion layer has a first region disposed on the first electrode and a second region disposed between the first region and the second electrode, and the metal is more difficult to diffuse into the second region than into the first region.
US08742389B2 Variable resistance memory device and method of forming the same
According to example embodiments, a variable resistance memory device may include memory cells, in which contact areas between word lines and a variable resistance layer are almost constant. The variable resistance memory device may include a vertical electrode on a substrate, horizontal electrode layers and insulating layers sequentially and alternately stacked on the substrate. The horizontal electrode layers and the insulating layers may be adjacent to the vertical electrode. The variable resistance layer may be between the vertical electrode the horizontal electrode layers. A thickness of one of the horizontal electrode layers adjacent to the substrate may be thickness than a thickness of an other of the horizontal electrode layers that is spaced apart from the substrate.
US08742385B2 Beam distortion control system using fluid channels
Paper and continuous web scanners operate at varying and high temperature conditions that cause distortion of the support beams and ultimately misalignment of the scanner heads. Circulating a heat transfer fluid between the support beams and through segmented fluid channels within the beam allows tuning of the beam's deflection when operating in an uneven thermal environment. The heat transfer rate can be modulated through various techniques, including: (1) varying the flow rate through each channel under manual or automatic control, (2) controlling the inlet fluid temperature of each channel with fluid immersion heaters or coolers, and (3) setting up the flow sequence via distribution channels that are, for example, in parallel, serial, or mixed.
US08742382B2 Neutron reflector block, side reflector including the neutron reflector block and nuclear reactor having such side reflector
The invention relates to a neutron reflector block. The neutron reflector block comprises a first portion and a second portion. The first portion has a first end face and oppositely located intermediate shoulders which are spaced from the first end face. The first end face and the intermediate shoulders are bounded by spaced side faces and spaced upper and lower faces. The second portion protrudes from the first portion between the intermediate shoulders and has spaced side faces and spaced upper and lower faces. The second portion side faces are more narrowly spaced relative to the first portion side faces. The second portion also has a second end face located oppositely to the first end face.
US08742378B2 Target supply unit
A target supply unit may include: a reservoir for storing a target material; a heater provided inside the reservoir for heating the target material stored in the reservoir; a heater power supply for supplying current to the heater; and a target outlet for outputting the target material stored inside the reservoir.
US08742373B2 Method of ionization
A plasma is formed from one or more gases in a plasma chamber using at least a first power and a second power. A first ion species is generated at said first power and a second ion species is generated at said second power. In one embodiment, the first ion species and second ion species are implanted into a workpiece at two different energies using at least a first bias voltage and a second bias voltage. This may enable implantation to two different depths. These ion species may be atomic ions or molecular ions. The molecular ions may be larger than the gases used to form the plasma.
US08742369B2 Value documents and other articles having taggants that exhibit delayed maximum intensity emissions, and methods and apparatus for their authentication
Value documents or other articles having authentication features, authentication apparatuses, and methods of authentication are provided that relate to the use of taggants that absorb radiation from an illumination source and emit radiation in a manner that has a maximum intensity occurring a duration of time after the illumination source has been switched off. The taggants include a crystalline composition comprising a host crystal lattice doped with a first rare earth active ion, and in some examples a second rare earth active ion.
US08742367B2 Multi-purpose measurement system
An apparatus for optically analyzing samples contained in sample sites of a sample holder, the apparatus has a first light source and at least one second light source, a monochromator having an input to which first light source is optically connected or connectable and an output for monochromatized light, light guiding portion for guiding light originating from the first and from the at least one second light sources to the sample sites, and a detector for detecting light from the sample sites. A light relay having a first input optically connected to the output of the monochromator, at least one second input optically connected or connectable to a second light source such that the light from the second light source by-passes the monochromator, and a first output for guiding light from selected input of the light relay to the sample sites. Based on the apparatus and light relay a versatile sample analyzer can be achieved in a cost-effective manner.
US08742363B2 Method and apparatus for ionizing gases using UV radiation and electrons and identifying said gases
The invention relates to a method for ionizing and identifying gases, wherein the gases to be identified are ionized in a reaction chamber and the product ions are measured, wherein the measurement of the product ions takes place via electrical fields acting on the product ions and the detection is performed with a detector for ions. It is provided that ionization takes place via UV radiation, and that simultaneously or sequentially ionization by electrons takes place. The invention further relates to a device for ionizing and identifying gases, which includes an ion source chamber having an ion source and an ion mobility spectrometer. For this purpose, a partition between the ion source chamber and the ion mobility spectrometer has a UV-transparent window and a window permeable for electrons, wherein UV radiation and electron radiation can be generated in the ion source chamber with the ion source.
US08742362B2 Laser ion source
According to one embodiment, a laser ion source is configured to generate ions by application of a laser beam, the laser ion source including a case to be evacuated, an irradiation box disposed in the case and including a target which generates ions by irradiation of laser light, an ion beam extraction mechanism which electrostatically extracts ions from the irradiation box and guides the ions outside the case as an ion beam, a valve provided to an ion beam outlet of the case, the valve being opened at ion beam emission and being closed at other times, and a shutter provided between the valve and the irradiation box, the shutter being intermittently opened at ion beam emission and being closed at other times.
US08742360B2 Compton camera
Plural camera heads are each placed in a position capable of detection of radiation emitted from a radiation source. Compton cones obtained from the detection data output from each of the plural camera heads are projected onto three-dimensional space and an image based on the radiation source is reconstructed. In addition, projected images from projecting Compton cones obtained from the detection data output from each camera head onto two-dimensional planes are also employed for determining a three-dimensional space excluding regions where the radiation source is not present. Reconstruction of images based on the radiation source is then performed within the determined three-dimensional space.
US08742357B2 Radiation sensor and dosimeter
A semiconductor radiation sensor (100), comprising a substrate (102), a carrier material (104) mounted to the substrate (102), and a semiconductor detector (106) mounted to the carrier material (104). A radiation sensitive portion of the semiconductor detector (106) is oriented towards the carrier material (104) and generally away from the substrate (102), and the carrier material is adapted to transmit radiation to the radiation sensitive portion of the semiconductor detector (106). A dosimeter comprising the radiation sensor (100) and a method of manufacturing the radiation sensor (100) are also provided.
US08742352B2 Occupancy sensor with multi-position rotary switch
An occupancy sensor has a body and a lens cover. The body includes an enclosure, a human movement sensing component and at least one multi-position rotary switch. The at least one multi-position rotary switch is configured through the enclosure of the body, has a plurality of switching positions and is rotatable between the switching positions. The lens cover is attached to the body and covers the human movement sensing component. With the above-mentioned structure, a user can easily and accurately rotate the multi-position rotary switch to adjust a function of the sensor because the multi-position rotary switch can be positioned in one of the switching positions, and thereby no excessive or deficient adjustment will be made.
US08742349B2 Portable radiographic detector exterior battery latch and methods for using the same
A radiographic imaging detector can include a housing, a radiographic imaging array enclosed by the housing, and a recess to releasably contain a battery in an outer surface of the housing. Certain exemplary embodiments of securing methods and/or battery latch apparatus for the closable recess of the DR detector can include a first catch mechanism configured to be released by force applied in a first direction, a second catch mechanism released by force applied in a second direction different from the first direction, where movement in the first direction can operate to disengage the first catch mechanism from the second catch mechanism, where movement in the second direction can operate to disengage the second catch mechanism for access to the recess, where the second catch mechanism is nearby the first catch mechanism, and where the first and second catch mechanism are actuated using one hand of an operator.
US08742348B2 Muon monitoring system for charged particle radiation therapy
A muon monitoring system for particle radiation therapy includes: a shield for a selective passing, by eliminating particles and radiation produced due to the high energy particles and radiation pulses, of the delay positrons emitted due to decay of muons stopped at a position corresponding to the Bragg peak position; a positron detector for detecting positrons from a designated direction and detecting the delay positrons passed through the shield opening by each of positron detecting plates for providing information of positron produced positions and time of delay simultaneous signals; and a control/analysis apparatus generating a delay signal at a timing delayed by a predetermined time period from a completion of irradiation of the high energy particle radiation pulses, and performing a process to generate μSR signals segmented for each positron generating position by analyzing detected results obtained by operating the positron detector for a predetermined number of times.
US08742346B1 Sputter removal of material from microscopy samples with RF generated plasma
A plasma system for changing a microscopy material sample comprises a microscopy material sample holder for holding a microscopy material sample in place in a desired orientation, and a receptacle holder for receiving the sample holder and an RF antenna. The microscopy sample is positioned relative to the antenna so that no point on the antenna is in direct line-of-sight contact with the microscopy sample. This feature of avoiding direct line-of-sight contact between the antenna and the sample assists in preventing, or at least minimizing, ion sputtering of system component material onto the specimen or sample 10 that is being trimmed. Moreover, portions of the system which are in direct line-of-sight contact with the sample are comprised of material having a low sputtering yield, preferably carbon. The material may comprise graphite, and may be in the form of a carbon coating or a carbon paint.
US08742345B1 Method for detecting electron beam of scanning electron microscope and for detecting fine patterns
Methods for detecting an electron beam of a SEM and for detecting fine patterns are provided. Line patterns having a length in a first direction can be formed on a detection sample. A power spectral density (PSD) curve of a standardized model, formed under a same exposure process of the detection sample, can be obtained. An edge contour of each line pattern of the detection sample can be obtained by the SEM and can be sampled at a sampling frequency to obtain a variation range at a sampling point on the edge contour in a second direction that is perpendicular to the first direction. A PSD curve of the detection sample can be obtained according to the variation range and can be compared with the PSD curve of the standardized model to determine whether an electron beam of the SEM has a high quality in the second direction.
US08742342B2 Electron microscope
A scanning electron microscope suppresses a beam drift by reducing charging on a sample surface while suppressing resolution degradation upon observation of an insulator sample. An electron microscope includes an electron source and an objective lens that focuses an electron beam emitted from the electron source, which provides an image using a secondary signal generated from the sample irradiated with the electron beam. A magnetic body with a continuous structure and an inside diameter larger than an inside diameter of an upper pole piece that forms the objective lens is provided between the objective lens and the sample.
US08742341B2 Testing apparatus using charged particles and device manufacturing method using the testing apparatus
A system for further enhancing speed, i.e. improving throughput in a SEM-type inspection apparatus is provided. An inspection apparatus for inspecting a surface of a substrate produces a crossover from electrons emitted from an electron beam source 25•1, then forms an image under a desired magnification in the direction of a sample W to produce a crossover. When the crossover is passed, electrons as noises are removed from the crossover with an aperture, an adjustment is made so that the crossover becomes a parallel electron beam to irradiate the substrate in a desired sectional form. The electron beam is produced such that the unevenness of illuminance is 10% or less. Electrons emitted from the sample W are detected by a detector 25•11.
US08742340B2 Methods of preparing liquid blends for building calibration curves for the effect of concentration on laser-induced fluorescence intensity
Disclosed herein are methods for determining and replicate unknown ratios of original target liquid blends, such as hydrocarbon fuel blends or contaminants, by using an in-process fluorescence-monitored procedure. The methods rely on trial-and-error mixing of the fuel ingredients into a single container. At the end of the trial-and-error procedure, the formed blend becomes an exact replica of the target fuel blend. The methods can also be used to build calibration curves without employing sets of previously prepared standard solutions.
US08742337B2 Ion source with surface coating
A mass spectrometer includes an Electron Impact (“EI”) or a Chemical Ionization (“CI”) ion source, and the ion source includes a first coating or surface. The first coating or surface is formed of a metallic carbide, a metallic boride, a ceramic or DLC, or an ion-implanted transition metal.
US08742336B2 Bio-chip for secondary ion mass spectroscopy and method of fabricating the same
There are provided a bio-chip for secondary ion mass spectrometry and a method of fabricating the same, the bio-chip, which is a bio-chip for analyzing a biochemical material using the secondary ion mass spectrometry, including: a substrate; and core-shell particles positioned above substrate, wherein the core-shell particles each include a metal nanoparticle as a core and a metal shell surrounding the metal nanoparticle.
US08742333B2 Method to perform beam-type collision-activated dissociation in the pre-existing ion injection pathway of a mass spectrometer
Described herein are methods and systems related to the use of the pre-existing ion injection pathway of a mass spectrometer to perform beam-type collision-activated dissociation, as well as other dissociation methods. Following injection and selection of a particular ion type or population, that population can be fragmented using the pre-existing ion injection pathway or inlet of a mass spectrometer. This is achieved by transmitting the ions back along the ion injection pathway. As the ions pass into the higher pressure regions located in or near the atmospheric pressure inlet, the ions are fragmented and then trapped. Following fragmentation and trapping, the ions can either be re-injected into the primary ion selection device or sent on to a secondary mass analyzer.
US08742332B2 Mass spectrometer and mass spectrometry method
A mass spectrometer and a mass spectrometry method adapted for mass spectrometry of a hardly volatile minuscule organic foreign matter of several μm often causing a device defect are disclosed. A sample gasified by a sample heating probe is introduced into an ion source, and the sample thus ionized is detected by being separated in accordance with the mass-to-charge ratio. In this mass spectrometry technique, the sample heating probe is covered with a cylindrical gas guide mechanism, and the gasified sample is led efficiently to the ion source by the gas guide mechanism, thereby making possible the contribution by the sample components which otherwise might be dispersed and wasted in the prior art. As a result, the mass spectrometry with higher sensitivity and S/N than in the prior art is realized.
US08742331B2 Imidazolium-based liquid salts and methods of use thereof
Imidazolium-based dicationic liquid salts and methods of using such imidazolium-based dicationic liquid salts in techniques such as ESI-MS are provided.
US08742330B2 Specific phase range for ion injection into ion trap device
When ions accumulated in the exit side end of ion guide are to be injected into ion trap as packets, the application of square wave high frequency voltage to ring electrode from main voltage generating unit is stopped. Once nearly all the ions have been injected into ion trap, the application of square wave high frequency voltage from main voltage generating unit to ring electrode is momentarily started, at which time the application of square wave high frequency voltage is started from a phase in the range of 90°±40° or 270°±40°. It is thereby possible to reduce the extent of spread of ions immediately after application of high frequency voltage and to improve the ion trapping efficiency.
US08742325B1 Photodetector array on curved substrate
In some applications, it may be desirable to position multiple photodetectors at precise locations on a curved focal surface defined by an optical system. To achieve this positioning, the photodetectors may be mounted at desired locations on a flexible substrate that is in a flat configuration. The flexible substrate with mounted photodetectors can then be shaped to substantially conform to the shape of the curved focal surface. This shaping can be accomplished by clamping the flexible substrate between at least two clamping pieces. The curved flexible substrate clamped between the at least two clamping pieces can be positioned relative to the optical system such that the photodetectors are positioned at desired three-dimensional locations on the curved focal surface.
US08742324B2 Structure for shielding a gap between members
An imaging device support structure includes a master flange having an opening portion through which an optical axis A passes, an imaging device which is attached to the master flange via the attachment plate and is positioned in the opening portion as viewed in an optical axis A direction, and a shielding member which shields a gap between the master flange and the imaging device in the opening portion. The shielding member is pressed against the opening edge of the first opening portion. The opening edge of the first opening portion has a substantially polygonal shape with corner portions which outwardly protrude.
US08742322B2 Encoder and interferometer that generate M-phase signals by multiplying N-phase signals by M coefficient sets, where N is not less than 6 and M is not smaller than 2
The laminated diffractive optical element includes plural diffraction gratings (21, 22 and 23) laminated with each other, the respective diffraction gratings being formed of a same light-transmissive material. In the element, reflective films are formed on grating surfaces (11 and 12) of the respective diffraction gratings, each of the reflective films being disposed between the diffraction gratings. Each of the reflective films reflects light in a specific wavelength range and transmits light in a wavelength range different from the specific wavelength range, the specific wavelength ranges of the respective reflective films being different from each other. The grating surfaces of the respective diffraction gratings are formed in shapes different from each other according to the specific wavelength ranges corresponding to the respective reflective films.
US08742321B2 Origin location detection circuit
An origin location detection circuit in an encoder. The encoder includes a scale on which an origin pattern indicating an origin is provided and a detection head relatively displaceable with respect to the scale. The origin location detection circuit includes a comparator for generating an origin signal indicating a location of the origin from an output voltage signal, which is output from a detector of the detection head and has been affected by involvement of the origin pattern; a DC voltage detection circuit smoothing the output voltage signal; and a differential amplifier circuit performing differential amplification of the output voltage signal and a DC voltage signal output from the DC voltage detection circuit. A differential amplifier signal of the differential amplifier circuit is input to the comparator.
US08742320B2 Spectral module and method for manufacturing spectral module
The present invention provides a highly reliable spectral module. When light L1 proceeding to a spectroscopic unit (4) passes through a light transmitting hole (50) in the spectral module (1) in accordance with the present invention, only the light having passed through a light entrance side unit (51) formed such as to become narrower toward a substrate (2) and entered a light exit side unit (52) formed such as to oppose a bottom face (51b) of the light entrance side unit (51) is emitted from a light exit opening (52a). Therefore, stray light M incident on a side face (51c) or bottom face (51b) of the light entrance side unit (51) is reflected to the side opposite to the light exit side unit (52) and thus is inhibited from entering the light exit side unit (52). Therefore, the reliability of the spectral module (1) can be improved.
US08742317B2 Visible light receiver circuit
A visible light receiver circuit, which reduces the influence of ambient light, has a simple configuration, and generates low noise, is provided. The visible light receiver circuit includes a photoelectric conversion unit. The photoelectric conversion unit includes a photodiode having a cathode connected to a power source, a resistor connected in series to an anode of the photodiode, and a nonlinear resistive circuit connected in parallel to the resistor. The nonlinear resistive circuit includes, for example, a series circuit including a Zener diode and a resistor.
US08742312B2 Optical detector suitable for use in light curtains
A planar detector for use in light curtains, which generates electric signals as a function of absorbed light and is provided with a plurality of tapping points for the generated signals. The magnitude of the signals at the respective tapping points is dependent on their distance to the partial surfaces where the light is absorbed. As a function of the magnitude ratios between the signals at several tapping points, the distance ratios of the respective tapping points to those partial surfaces, where the light is absorbed, can be calculated. The detector is configured as a flexible layered structure made of organic material. The tapping points are disposed at a distance from the edges of the layered structure. Electric connection lines to the tapping points are connected along their longitudinal extension to the layered structure of the detector.
US08742308B2 Imaging array device structure with separate charge storage capacitor layer
An imaging array comprises a photodetector layer, a readout IC (ROIC) layer, and a charge storage capacitor layer which is distinct from the photodetector and ROIC layers; the layers are electrically interconnected to form the array. The capacitors within the charge storage capacitor layer are preferably micromachined; the charge storage capacitor layer can be an interposer layer or an outer layer.
US08742307B2 Solar panel device
The invention relates to a solar panel device that comprises a fixed anchoring holder (10), which includes at least one mobile panel holder (20) bearing at least one solar panel (30, 31), at least three jacks (40, 41, 42) with a jack body connected to the anchoring holder and a mobile rod capable of translation in said body, and at least three ball and socket joints (50, 51, 52). Each ball and socket joint is connected (i) to the mobile panel holder and (ii to the rod of the jacks, and the mobile panel holder (i) is capable of translation and (ii) can be oriented according to the respective position of the rods of the at least three jacks. The invention can particularly be used for producing electricity in residential housings.
US08742306B2 Calibrated energy transfer
Apparatuses, methods, kits, and systems relating to transferring electromagnetic energy to an energy application zone via a source of electromagnetic energy are disclosed. Some apparatuses may include a processor configured to determine a preliminary amount of energy to be dissipated in an object located at least partially in the energy application zone and determine a corrected amount of energy based on the preliminary amount of energy and calibration information. The processor may be further configured to estimate an amount of energy dissipated in the object. The processor may also be configured to cause the source to transfer energy to the energy application zone at least until the energy dissipated in the object as estimated equals the corrected amount of energy.
US08742300B2 Inverter system
An inverter system includes inverting circuitry for inverting an input DC signal into a square wave or quasi-square wave AC signal across a resistance, and a controller for causing the inverting circuitry to invert the input DC signal into the AC signal. The DC signal is a DC voltage having a value that ranges from 24-32 volts DC. The AC signal is an AC voltage having a value that ranges from 115-230 volts AC RMS.
US08742298B2 Dental firing or press furnace
The invention relates to a dental firing or press furnace (10) that enables the production of at least one dental restoration part (62). The dental firing or press furnace is provided with a firing space (12) that is heatable with the aid of a heating device (22), preferably, a resistance heating device. A heat-conducting element (50) having a specific thermal conductivity of at least 100 W/mK is arranged on the floor of the firing space (12).
US08742290B2 Robot system
This robot system includes a robot, a laser emitting portion moved by the robot, emitting a laser beam to a target workpiece, and a control portion controlling the laser emitting portion to emit the laser beam on the basis of information regarding an arbitrarily-shaped work locus and movement information of the laser emitting portion.
US08742289B2 Laser lift-off apparatus
In order to separate a material layer from a substrate at the boundary face between the substrate and the material layer, a laser light is applied to a workpiece from the substrate side through a mask, the work having the material layer formed on the substrate. The laser beam is split into a plurality of small area laser light by the mask 44, and two or more irradiation regions are formed on the workpiece. Adjacent irradiation regions are separated from each other, and an edge part of each irradiation region and an edge part of an adjacent irradiation region, which extend in a direction parallel to the relative moving direction of the workpiece, are arranged such that the edge of the irradiation region and the edge of the adjacent irradiation region are sequentially overlapped each other as the work is moved.
US08742287B2 Lighting solution for apparatuses for vacuum insulating glass (VIG) unit tip-off, and/or associated methods
Certain example embodiments of this invention relate to apparatuses for sealing the tips of pump-out tubes of vacuum insulating glass (VIG) units, and/or associated methods. In certain example embodiments, a laser source used in sealing the pump-out tube is thermally insulated from the VIG unit and emits a laser beam through one or more windows in an oven towards a mirror located therein. The mirror is located so as to redirect the laser beam onto the pump-out tube to thereby seal it. For instance, a substantially horizontal laser beam emitted from a laser source located outside the oven enters into the oven through one or more windows and is reflected by a mirror towards the pump-out tube to be sealed. The repositioning of the laser source advantageously can change its effective focal length and/or the location of the laser beam, e.g., because of the fixed location of the mirror.
US08742285B2 Method of oxidation utilizing a gliding electric arc
A method for oxidizing a combustible material. The method includes introducing a volume of the combustible material into a plasma zone of a gliding electric arc oxidation system. The method also includes introducing a volume of oxidizer into the plasma zone of the gliding electric arc oxidation system. The volume of oxidizer includes a stoichiometrically excessive amount of oxygen. The method also includes generating an electrical discharge between electrodes within the plasma zone of the gliding electric arc oxidation system to oxidize the combustible material.
US08742283B2 Induction device
A device for sustaining a plasma in a torch is provided. In certain examples, the device comprises a first electrode configured to couple to a power source and constructed and arranged to provide a loop current along a radial plane of the torch. In some examples, the radial plane of the torch is substantially perpendicular to a longitudinal axis of the torch.
US08742282B2 Ablative plasma gun
A plasma gun with two gap electrodes on opposite ends of a chamber of ablative material such as an ablative polymer. The gun ejects an ablative plasma at supersonic speed. A divergent nozzle spreads the plasma jet to fill a gap between electrodes of a main arc device, such as an arc crowbar or a high voltage power switch. The plasma triggers the main arc device by lowering the impedance of the main arc gap via the ablative plasma to provide a conductive path between the main electrodes. This provides faster triggering and requires less trigger energy than previous arc triggers. It also provides a more conductive initial main arc than previously possible. The initial properties of the main arc are controllable by the plasma properties, which are in turn controllable by design parameters of the ablative plasma gun.
US08742277B2 Method for separating mineral impurities from calcium carbonate-containing rocks by X-ray sorting
The present invention relates to a method for separating mineral impurities from calcium carbonate-containing rocks by comminuting the calcium carbonate-containing rocks to a particle size in the range of from 1 mm to 250 mm, separating the calcium carbonate particles by means of a dual energy X-ray transmission sorting device.
US08742275B1 Cantilevered integrated function keys
According to one general aspect of the invention, an input device includes a collapsible structure and a sheet of material. The sheet of material is disposed above the collapsible structure and includes an attached edge that is affixed to a housing of the input device, creating a pivot point. The sheet of material also includes a front edge opposite the attached edge, a left edge, and a right edge. The sheet of material has a width extending from the left edge to the right edge and a height extending from the front edge to the pivot point. A first opening is formed proximate the front edge of the sheet of material. The collapsible structure is disposed below a portion of the sheet of material located between the front edge and a midpoint of the height of the sheet. The collapsible structure is approximately centered between the left and right edges.
US08742274B2 Switching device
In a switching device (1), in particular a line circuit breaker and/or a residual current circuit breaker, having a housing (2) and having switching contacts for closing and/or opening at least one circuit, wherein a tripping apparatus for automatically disconnecting the switching contacts is provided, wherein the housing (2) has at least one front side (3), the invention proposes, for the purpose of meeting changing requirements from the market or the customers quickly, flexibly and at favorable cost, clipping a cover cap (4) onto the front side (3).
US08742272B2 Electrical contacts with laser defined geometries
According to various aspects, exemplary embodiments are provided of electrical contacts, which may be used for establishing an electrical pathway between first and second electrically conductive surfaces. In an exemplary embodiment, an electrical contact may include an electrically conductive base member and at least one resilient contact member. The at least one resilient contact member may have a configuration at least partially defined by a laser cut in or into the electrically conductive base member. The at least one resilient contact member may also be formed so as to protrude outwardly from the electrically conductive base member.
US08742267B2 Electromagnetic interference shielding assembly and electronic device having same
An electromagnetic interference shielding assembly for use in an electronic device is disclosed. The electronic device includes a circuit board and an alternating current cable including one end connected to the circuit. The electromagnetic interference assembly includes an electromagnetic interference shielding plate. The circuit board is mounted on the electromagnetic interference shielding plate. The alternating current cable includes a segmental portion arranged adjacent to the electromagnetic interference shielding plate. The segmental portion extends substantially parallel to the electromagnetic interference shielding plate. The electromagnetic interference shielding plate defines a plurality of slots each extending in a direction perpendicular to an extending direction of the segmental portion of the alternating current cable. The parallel slots, as a whole, extend along the extending direction of the segmental portion and spatially corresponding to the segmental portion.
US08742261B2 Transparent conductive film and touch panel using the same
A transparent conductive film includes a number of first transparent conductive stripes extending along a first direction and a number of second transparent conductive stripes extending along a second direction and intersecting the number of first transparent conductive stripes. The first conductive stripes are spaced from each other and extend substantially along a first direction. The second transparent conductive stripes are spaced from each other and extend substantially along a second direction. The first transparent conductive stripes are electrically connected with the second transparent conductive stripes. The first transparent conductive stripes and the second conductive stripes are arranged in patterns such that the transparent conductive film has an anisotropic impedance. The first direction is a low impedance direction. A resistivity of the transparent conductive film in the low impedance direction is smaller than the resistivity of the transparent conductive film in the second direction and any other direction.
US08742257B2 Terminal fixing device for control cable
A cable cap of a control cable has a small-diameter portion and a large-diameter portion on an outer tube side, and a large-diameter portion on a tip side. A bracket includes a cutout groove, into which the small-diameter portion of the cable cap can be inserted from above, an engaging projection that is formed in such a manner as to project from an inner wall of the cutout groove toward another inner wall opposite to the inner wall, and an engaging recess to be engaged with an edge portion of an outer peripheral surface of the large-diameter portion on the outer tube side in a state in which the outer tube side of the control cable is inclined around the small-diameter portion as a fulcrum engaged with the engaging projection by operating force from the outside.
US08742256B2 Electronic device enclosure
An electronic device enclosure includes a rear panel and a blocking board. The rear panel comprises a front surface and a back surface opposite to the front surface. A through opening is defined in the rear panel. The blocking board comprises a main body, a first flange and a second flange opposite to the first flange. A first stopping piece is extends from the first flange. A second stopping piece is extended from the second flange. A latch portion is located on the first flange. A first protrusion is located on the second flange. The latch portion and the second protrusion extend through the through opening by being elastically deformed, the latch portion and the second protrusion abut on the front surface, and the first stopping piece and the second stopping piece abut on the back surface.
US08742252B2 Elongated photovoltaic cells in casings with a filling layer
A solar cell unit comprising a cylindrical shaped solar cell and a transparent tubular casing is provided. The tubular shaped solar cell comprises a back-electrode, a semiconductor junction circumferentially disposed on the back-electrode and a transparent conductive layer disposed on the semiconductor junction. The transparent tubular casing is circumferentially sealed onto the transparent conductive layer of the cylindrical shaped solar cell. A solar cell unit comprising a cylindrical shaped solar cell, a filler layer, and a transparent tubular casing is provided. The cylindrical shaped solar cell comprises a cylindrical substrate, a back-electrode circumferentially disposed on the cylindrical substrate, a semiconductor junction circumferentially disposed on the back-electrode, and a transparent conductive layer disposed on the semiconductor junction. The filler layer is circumferentially disposed on the transparent conductive layer and the transparent tubular casing is circumferentially disposed onto the filler layer.
US08742244B2 Electronic hi-hat cymbal controller
An electronic hi-hat cymbal controller is disclosed. The controller includes a hi-hat cymbal stand having a pedal and a shaft. The pedal is configured and arranged to move the shaft. A lower cymbal is mounted to the hi-hat cymbal stand and an upper cymbal is mounted to the shaft. A sensor assembly is mounted to the hi-hat cymbal stand. The sensor assembly is configured and arranged to detect the position of the upper cymbal relative to the lower cymbal.
US08742240B2 Tom holder
A tom holder has a holder body, a pivoting member supported pivotably with respect to the holder body, and a rod, which projects from the pivoting member with the tom fixed to the rod. The tom holder has a pair of openings located at opposed positions. The tom holder is configured to be usable in either a first mode, in which the rod projects from the first opening, and a second mode, in which the rod projects from the second opening.
US08742237B1 Haploid-inducer corn line designated AX6012
A haploid-inducer corn line, designated AX6012, the plants and seeds of the haploid-inducer corn line AX6012, methods for producing a corn plant, either inbred or hybrid, produced through use of the haploid-inducer corn line AX6012 are disclosed. This invention also relates to methods for generating homozygous diploid corn plants from heterozygous diploid corn plants.
US08742233B2 Variety corn line NPFA6899
The present invention provides an inbred corn line designated NPFA6899, methods for producing a corn plant by crossing plants of the inbred line NPFA6899 with plants of another corn plant. The invention further encompasses all parts of inbred corn line NPFA6899, including culturable cells. Additionally provided herein are methods for introducing transgenes into inbred corn line NPFA6899, and plants produced according to these methods.
US08742231B1 Maize inbred PH1M3D
A novel maize variety designated PH1M3D and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1M3D with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1M3D through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1M3D or a locus conversion of PH1M3D with another maize variety.
US08742230B1 Maize inbred PH12JZ
A novel maize variety designated PH12JZ and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH12JZ with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH12JZ through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH12JZ or a locus conversion of PH12JZ with another maize variety.
US08742228B2 Plants and seeds of hybrid corn variety CH095686
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH095686. The invention thus relates to the plants, seeds and tissue cultures of the variety CH095686, and to methods for producing a corn plant produced by crossing a corn plant of variety CH095686 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH095686.
US08742219B2 Soybean variety XB31Q12
A novel soybean variety, designated XB31Q12 is provided. Also provided are the seeds of soybean variety XB31Q12, cells from soybean variety XB31Q12, plants of soybean XB31Q12, and plant parts of soybean variety XB31Q12. Methods provided include producing a soybean plant by crossing soybean variety XB31Q12 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB31Q12, methods for producing other soybean varieties or plant parts derived from soybean variety XB31Q12, and methods of characterizing soybean variety XB31Q12. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB31Q12 are further provided.
US08742213B2 Soybean cultivar S090160
A soybean cultivar designated S090160 is disclosed. The invention relates to the seeds of soybean cultivar S090160, to the plants of soybean cultivar S090160, to the plant parts of soybean cultivar S090160, and to methods for producing progeny of soybean cultivar S090160. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar S090160. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar S090160, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar S090160 with another soybean cultivar.
US08742212B2 Soybean cultivar S080197
A soybean cultivar designated S080197 is disclosed. The invention relates to the seeds of soybean cultivar S080197, to the plants of soybean S080197, to plant parts of soybean cultivar S080197, and to methods for producing a soybean plant produced by crossing soybean cultivar S080197 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars, or breeding cultivars, and plant parts derived from soybean variety S080197, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar S080197, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing the cultivar S080197 with another soybean cultivar.
US08742209B2 Melon variety NUN 1101
The invention relates to the field of Cucumis melo, in particular to a new variety of Cucumis melo reticulatus, NUN 1101 ME, plants, seeds and melon fruits.
US08742206B2 Multileaf spinach
Spinach having significantly more leaves per plant as compared to known spinach and, inter alia, cells of these plants, seeds and other propagation material as well as harvestable parts of these plants, and methods for obtaining, and using and uses of these plants and parts thereof.
US08742205B2 Dominant negative mutant KRP protein protection of active cyclin-CDK complex inhibition by wild-type KRP
Disclosed are mutant CDK inhibitor (CKI) polypeptides having dominant negative antagonist activity against wild-type CKI proteins, as well as related compositions, including nucleic acids and vectors encoding the mutant CKI polypeptides and transformed host cells and transgenic plants comprising such nucleic acids and vectors. Also disclosed are related methods for using the mutant proteins to modulate cell division in cells, particularly plant cells.
US08742200B2 Derivation of embryonic stem cells and embryo-derived cells
This present invention provides novel methods for deriving embryonic stem cells and embryo-derived cells from an embryo without requiring destruction of the embryo. The invention further provides cells and cell lines derived without embryo destruction, and the use of the cells for therapeutic and research purposes. It also relates to novel methods of establishing and storing an autologous stem cell line prior to implantation of an embryo, e.g., in conjunction with reproductive therapies such as IVF.
US08742199B2 Absorbent article having dryness indicating graphic
An absorbent article including features facilitating toilet training of a wearer is provided. The article includes at least a first appearing graphic that changes from an initial, less visible state to a subsequent, more visible state in the absence of wetness, thereby to provide positive encouragement to a child during toilet training. The appearing graphic becomes less visible if subjected to liquid. A wetness sensation member may also be provided to give tactile, negative sensation to the child, thereby giving feedback received by at least two different senses. Additionally or alternatively, a second appearing graphic, different from the first appearing graphic, may be provided to increase a child's interest in the toilet training process. The first and second appearing graphics may become visible at different times, thereby providing a sequential or spaced reveal of the image.
US08742198B2 Dehydration sensors having polymeric base-buffered inks
A dehydration sensor having a stable, printable, buffered-ink composition that enables one to miniaturize the detection zone and permits both buffer and indicator dye to be applied in the same area of a detection zone, without need for a conventional, large buffer pad region. The ink composition includes a weak polymeric base as its primary buffering agent.
US08742194B2 Hydrocarbon-containing mixture and method and system for making the same
A hydrocarbon-containing mixture including acetylene and butenyne is disclosed. The hydrocarbon-containing mixture can include 10% to 89% acetylene, 10% to 89% butenyne, and at least 0.25% dimethyl butadiyne. A method and system for producing the hydrocarbon-containing mixture is also disclosed. The system can include an acetylene production subsystem comprising at least one vessel and an acetylene output for delivering acetylene to a finishing vessel via a finishing vessel inlet. The finishing vessel can include a diffuser in fluid communication with the finishing vessel inlet, and gas exiting the diffuser can pass through a reaction chamber filled with solid calcium carbide before passing through a finishing vessel outlet.
US08742189B2 Catalyst for the dehydroaromatisation of methane and mixtures containing methane
The present invention relates to a catalyst for dehydroaromatizing C1-C4-aliphatics, said catalyst being obtainable by twice treating a zeolite from the group of MFI and MWW with NH4-containing mixtures, in each case with subsequent drying and calcination. The catalyst comprises molybdenum and, if appropriate, as further elements, Cu, Ni, Fe, Co, Mn, Cr, Nb, Ta, Zr, V, Zn and/or Ga.The present invention further provides a process for dehydroaromatizing a mixture comprising C1-C4-aliphatics by conversion in the presence of the catalyst.
US08742188B2 Process for preparing ethylene and/or propylene and an iso-olefin-depleted olefinic product
The present invention provides a process for preparing ethylene and/or propylene and an iso-olefin-depleted olefinic product, comprising the steps of: a) providing a C5 hydrocarbon-comprising stream, comprising C5 cyclopentene and C5 iso-olefins; b) subjecting the C5 hydrocarbon-comprising stream to an etherification process with methanol and/or ethanol wherein at least part of the C5 iso-olefins are converted with methanol and/or ethanol to an tert-alkyl ether, and retrieving an etherification product stream; c) separating at least part of the etherification product stream into at least an ether-enriched stream and a first iso-olefin-depleted olefinic product; d) converting at least part of the tert-alkyl ether in the ether-enriched stream to ethylene and/or propylene by contacting at least part of the ether-enriched stream with a molecular sieve-comprising catalyst at a temperature in the range of from 350 to 1000° C. and retrieving a second olefinic product comprising ethylene and/or propylene.
US08742184B2 Process for hydrogenation of carboxylic acids and derivatives to hydrocarbons
Process for hydrogenating a carboxylic acid or derivative thereof by feeding a carboxylic acid or derivative thereof and hydrogen to a reactor, maintaining conditions therein such that hydrogen reacts with the carboxylic acid and/or derivative thereof to form a product stream including one or more hydrocarbons and one or more oxides of carbon and feeding the product stream to a flash separator. A vapor fraction including the one or more oxides of carbon is separated from a liquid fraction having the one or more hydrocarbons. The concentration of carbon oxides in the flash separator is at or below a predetermined value.
US08742183B2 Production of aviation fuel from biorenewable feedstocks
A process has been developed for producing aviation fuel from renewable feedstocks such as plant oils and animal fats and oils. The process involves treating a renewable feedstock by hydrogenating and deoxygenating to provide n-paraffins having from about 8 to about 24 carbon atoms. At least some of the n-paraffins are isomerized to improve cold flow properties. At least a portion of the paraffins are selectively cracked to provide paraffins meeting specifications for different aviation fuels such as JP-8.
US08742179B2 Method for producing aryl, heteroaryl, or alkenyl-substituted unsaturated hydrocarbon
The present invention relates to a method for producing aryl-, heteroaryl- or alkenyl-substituted unsaturated hydrocarbons, containing: reacting aryl halides, heteroaryl halides or alkenyl halides with alkynes or alkenes in the presence of a palladium catalyst to obtain a crude product, and subsequently distillatively purifying the crude product in the presence of a compound having at least one NC═S group.
US08742170B2 Preparation of methionine or selenomethionine from homoserine via a 4-substituted 2-aminobutanoic acid intermediate
Provided herein are processes for the production of methionine or selenomethionine from homoserine. In particular, the processes proceed via the production of 4-substituted 2-aminobutanoic acid intermediates or derivatives thereof.
US08742169B2 Acrolein manufacturing method and acrylic acid manufacturing method
The present invention relates to a method for producing acrolein, comprising step (1) of subjecting glycerol to dehydration reaction in the presence of a copper compound and a compound containing a heteroatom; step (2) of recovering acrolein generated in the dehydration reaction step (1); step (3) of recovering part or all of the copper compound which remained after the recovery of acrolein; step (4) of treating part or all of the recovered copper compound with at least one member selected from a group consisting of an oxidizing agent and acid; and step (5) of returning part or all of the copper compound treated in the above step to step (1); and a method for producing acrylic acid, comprising reacting acrolein obtained by the above method with molecular oxygen. The production method of the present invention enables efficient production of acrolein and acrylic acid from glycerol contained in plant oil and animal fats derived from carbon dioxide in air without depending on the oxidation of propylene derived from fossil resources.
US08742165B2 Low interfacial tension surfactants for petroleum applications
The invention relates to a class of novel surfactants that have utility in the recovery and/or extraction of oil.
US08742163B2 Method for producing methacrylated benzophenones
The invention relates to a method for producing methacrylated benzophenones and to the uses thereof.
US08742158B2 Protease inhibitors
The present invention provides HIV protease inhibitors of formulas I, IA, IB, Ib or II, or pharmaceutically acceptable salts thereof, wherein R2 may be, for example, 2-pyridyl-CH2—, 3-pyridyl-CH2—, 4-pyridyl-CH2—, a sulfonyl group as described in the formulas herein including benzenesulfonyl or thiophenesulfonyl groups, R2a—CO)—, R2a being selected from the group consisting of piperonyl, 2-pyranzinyl (unsubstituted or substituted with H, or an alkyl of 1 to 4 carbon atoms) or a picolylamine group as described herein, wherein R3 may be, for example, a phenyl group or diphenylmethyl group as described herein, and wherein Cx may be, for example, COOH, CONR5R6, CH2OH or CH2OR7.
US08742154B2 Block ABA silicone polyalkyleneoxicie copolymers, methods of preparation, and applications for employing the same
There is provided herein a linear tri-block copolymer having the average formula (1): ABA  (1) wherein A is a polyalkyleneoxide unit or an aliphatic modified polyalkyleneoxide unit both of the general formula: R5O(CaH2aO)dY and wherein B is an internal polysiloxane unit of the general formula: [X(CaH2aO)bR2[SiO(R1)2]cSi(R1)2R2(OCaH2a)bX] wherein X and Y are divalent organic groups selected from a secondary amine or a tertiary amine and a ring-opened epoxide, such that when X is a ring-opened epoxide, Y is a secondary or tertiary amine, and when Y is a ring-opened epoxide, X is a secondary or tertiary amine. In addition, there is provided herein a method of making a linear tri-block copolymer having the average formula (1) and personal care and softener compositions comprising the same, specifically a hair conditioner.
US08742150B2 Castor oil fatty acid based estolide esters and their derivatives as potential lubricant base stocks
Castor oil was hydrolysed to castor fatty acids and self condensed to get a ricinoleic acid-based estolide of about 95 acid value. The carboxylic group of the estolide on subsequent esterification with linear or branched chain alcohols and also on acetylation of free hydroxy group yielded castor oil fatty acids based estolide esters and their acetates. All the products were evaluated for total acid number (TAN), viscosity, viscosity index, pour point, flash point, and copper strip corrosion and found to be potential lubricant basestocks.
US08742146B2 Process for improving the selectivity of an EO catalyst
The present invention relates to a process for improving the overall selectivity of an EO process for converting ethylene to ethylene oxide utilizing a highly selective EO silver catalyst containing a rhenium promoter wherein following normal operation a hard strip of the chloride on the surface of the catalyst is conducted in order to remove a portion of the chlorides on the surface of the catalyst. Following the hard strip, the catalyst is optionally re-optimized. Surprisingly, it has been found that the selectivity of the catalyst following the hard strip may be substantially higher than the selectivity prior to the hard strip.
US08742145B2 Method for manufacturing an epoxy compound and method for epoxidizing a carbon—carbon double bond
The present invention provides a method for producing an epoxy compound, comprising oxidizing a carbon-carbon double bond of an organic compound by hydrogen peroxide in the presence of a neutral inorganic salt and a mixed catalyst of a tungsten compound (a), at least one phosphorus compound selected from the group consisting of phosphoric acids, phosphonic acids, and salts thereof (b) and a surfactant (c), and an epoxidizing method comprising oxidizing a carbon-carbon double bond by hydrogen peroxide in the presence of the catalyst and the neutral inorganic salt.
US08742139B2 No-carrier-added nucleophilic [F-18] fluorination of aromatic compounds
Phenyliodonium ylide derivatives substituted with electron donating as well as electron withdrawing groups on the aromatic ring are shown for use as precursors in aromatic nucleophilic substitution reactions. The iodonium ylide group is substituted by nucleophiles such as halide ions to provide the corresponding haloaryl derivatives. No-carrier-added [F-18]fluoride ion exclusively substitutes the iodonium ylide moiety in these derivatives and provides high specific activity F-18 labeled fluoro derivatives. Protected L-dopa-6-iodonium ylide derivative have been synthesized as a precursors for the preparation of no-carrier-added 6-[F-18]fluoro-L-dopa. The iodonium ylide group in this L-dopa.derivative is nucleophilically substituted by no-carrier-added [F-18]fluoride ion to provide a [F-18]fluoro intermediates which upon acid hydrolysis yielded 6-[F-18]fluoro-L-dopa.
US08742138B2 Compounds as hypoxia mimetics, and compositions and uses thereof
This invention relates to new compounds that can serve as hypoxia mimetics. This invention also relates to methods of increasing HIF levels or activity in a subject or treating a condition associated with HIF levels or activity in a subject by administering to the subject at least one of these compounds.
US08742135B1 Compound amycolamicin, method for producing the same, and use of the same
A compound having a structure expressed by the following Structural Formula (1), tautomers thereof, or salts of the compound or the tautomers.
US08742132B2 Indolylmaleimide derivatives processes for their production and pharmaceutical compositions
A compound of formula (I) wherein R denotes another heterocyclic residue and wherein Ra, Rb, Rc, Rd and Re, are as defined in the specification, processes for their production, their uses, in particular in transplantation, and pharmaceutical compositions containing them.
US08742130B2 Hydrate forms of 1,2,4-triazole, processes for manufacture thereof, and compositions thereof
The present invention provides new hydrate forms of triazole, triazole alkaline salt, and alkali doped 1,2,4-triazole. The present invention also discloses processes for manufacturing new hydrate forms of triazole, triazole alkaline salt, and alkali-doped 1,2,4-triazole. The present invention also relates to compositions for different applications of new hydrate forms of triazole, triazole alkaline salt, and alkali doped 1,2,4-triazole. In addition, the present invention provides co-crystal form of triazole with acid, and methods of preparing thereof.
US08742128B2 Process for producing pyridine compound, and pyridine compound
Provided is a process for producing a high-purity pyridine compound from a crude pyridine compound that contains a diazine compound as an impurity, the method including a reaction step of reacting the crude pyridine compound with an aluminum hydride compound, and a distillation step of distilling the product obtained from the reaction step. The aluminum hydride compound preferably contains one or more compounds selected from lithium aluminum hydride and sodium aluminum hydride.
US08742122B2 Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
The present invention relates to a substantially a solid form of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Compound 1, Solvate Form A and Compound 1, HCl Salt Form A), processes for making such forms, pharmaceutical compositions thereof, and methods of treatment therewith.
US08742119B2 Pyruvate kinase M2 modulators, therapeutic compositions and related methods of use
Compositions comprising compounds that modulate pyruvate kinase M2 (PKM2) are described herein. Also described herein are methods of using the compounds that modulate PKM2 in the treatment of cancer.
US08742118B2 Methods for preparing intermediates of perampanel
Methods for the synthesis of 2-alkoxy-5-(pyridin-2-yl)pyridine of formula I or salts thereof are provided.
US08742117B2 Oxime derivatives
The present invention relates to novel oxime derivatives of the general formula (I), their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods for their preparation, use of these compounds in medicine and the intermediates involved in their preparation.
US08742116B2 Cycloalkylamine substituted isoquinolone derivatives
The invention relates to 6-substituted isoquinolone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
US08742115B2 Co-crystals and salts of CCR3-inhibitors
This invention relates to co-crystals and salts of CCR3 inhibitors of formula 1, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases related with the CCR3-receptor.
US08742114B2 Nucleic acid detections and methods of their use
The invention describes the preparation and use of fluorescent stains for nucleic acids derived from unsymmetrical cyanine dyes, dimmers, trimers, or tetramers. In particular, the invention describes unsymmetric cyanine dyes, dimmers, trimer and tetramers having a water soluble substituent. The dyes of the invention possess superior fluorescent properties when complexed with nucleic acids, and have utility in any application which requires detection of nucleic acids, such as detection of nucleic acids in solution, in gels, in blots, in microarrays, and in bacteria and cells, and for use in analysis of cell structure, membrane integrity, and function. The presence of the water soluble substituent results in improved water soluability and stability, resulting in improved detection of nucleic acids.
US08742112B2 Heterocyclic compound and its use for control of an arthropod pest
A heterocyclic compound represented by formula (1): wherein A1, A2, R1, R2, R3, R4, n and so on are defined in tha description, has an excellent control effect on arthropod pests and is useful for control of arthropod pests.
US08742111B1 Synthesis of intermediate anilino methyl esters used in the production of synthetic opioid analgesics
An improved process or method of synthesis of carfentanil and other potent opioid analgesics of the N-alkyl 4-substituted 4-piperidinylamide class which can be used as morphine substitutes.
US08742108B2 Light-emitting material comprising orthometalated iridium complex, light-emitting device, high efficiency red light-emitting device, and novel iridium complex
A light-emitting material comprises iridium and at least one ligand represented by the following formula: wherein R11 and R12 each represents an alkyl group, an aryl group, a heteroaryl group, an alkoxy group, a cyano group or a cyclic structure obtained by connection of one of a plurality of R11s to another of said plurality of R11s, or one of a plurality of R12s to another of said plurality of R12s, or one of the R11s to one of the R12s; m1 represents an integer from 0 to 4; m2 represents an integer from 0 to 6.
US08742106B2 Disubstituted heteroaryl-fused pyridines
The invention relates to compound of the formula (I′) in which the substituents are as defined in the specification; in free form or in salt form; to its preparation, to its use as medicament and to medicaments comprising it.
US08742105B2 Polymorphs of raltegravir potassium
The present invention provides novel polymorphs of raltegravir potassium, processes for their preparation and pharmaceutical compositions comprising them. Thus for example, raltegravir potassium was added to water and stirred for 15 minutes, the solution was filtered on hiflo bed and the bed washed with water, the resulting solution was subjected to freeze drying at −180 deg C. for 13 hours to give raltegravir potassium amorphous form.
US08742104B2 Saturated N-heterocyclic carbene-ligand metal complex derivatives, preparing method thereof, and preparing method of silane compound by hydrosilylation reaction using the same as catalyst
Provided are a saturated N-heterocyclic carbene-ligand metal complex derivative, a method for preparing the same, and a method for preparing a silane compound by hydrosilylation using the same as a catalyst. To describe in more detail, the metal complex derivative has a saturated N-heterocyclic carbene derivative and an olefin ligand at the same time. A silane compound is prepared by hydrosilylation in the presence of the metal complex derivative as a catalyst. The provided metal complex derivative of the present invention has superior stability during hydrosilylation reaction and is capable of effectively performing the hydrosilylation reaction at low temperature even with small quantity. Further, a product with superior regioselectivity may be obtained. In addition, after the hydrosilylation reaction is completed, the metal complex derivative may be recovered and recycled.
US08742102B2 Process for enantiomeric separation of racemic dihydro-1,3,5 triazines via preferential crystallization
A new process for the enantiomeric separation of racemic 3,6-dihydro-1,3,5-triazine derivatives for the treatment of disorders associated with insulin-resistance syndrome, by preferential crystallization.
US08742100B2 Small molecule inhibitors of isoprenylcysteine carboxyl methyltransferase with potential anticancer activity
The present invention generally relates to inhibitors of isoprenylcysteine carboxyl methyltransferase (Icmt), in particularly to compounds that inhibit Icmt activity and pharmaceutical compositions thereof. The invention also relates to methods of disease treatment using the same.
US08742094B2 Method for the solid phase-based production of phosphate-bridged nucleoside conjugates
The invention relates to a method for producing phosphate-bridged nucleoside conjugates. In the method, a cyclosaligenyl nucleotide is produced first, to which a linker is added, which is used to perform the immobilization on a solid phase. A subsequent reaction with corresponding nucleophiles results in the desired phosphate-bridged nucleoside conjugates, which can then again be cleaved from the solid phase-bound linker.
US08742089B2 Methods and compositions for expressing negative-sense viral RNA in canine cells
The present invention provides novel canine pol I regulatory nucleic acid sequences useful for the expression of nucleic acid sequences in canine cells such as MDCK cells. The invention further provides expression vectors and cells comprising such nucleic acids as well as methods of using such nucleic acids to make influenza viruses, including infectious influenza viruses.
US08742087B2 Mucin antigen vaccine
Provided are expression vectors for generating an immune response to a mucin. The vectors comprise a transcription unit encoding a secretable polypeptide, the polypeptide comprising a secretory signal, a mucin antigen and CD40 ligand. Also provided are methods of generating an immune response against cells expressing a mucin by administering an effective amount of the vector. Further provided are methods of generating an immune response against cancer cells expressing a mucin in an individual by administering an effective amount of the vector. Still further provided are methods of overcoming anergy to a mucin self antigen by administering an effective amount of the vector.
US08742086B2 Polynucleotide encoding a mutant dehalogenase to allow tethering to functional groups and substrates
A mutant hydrolase optionally fused to a protein of interest is provided. The mutant hydrolase is capable of forming a bond with a substrate for the corresponding nonmutant (wild-type) hydrolase which is more stable than the bond formed between the wild-type hydrolase and the substrate and has at least two amino acid substitutions relative to the wild-type hydrolase. Substrates for hydrolases comprising one or more functional groups are also provided, as well as methods of using the mutant hydrolase and the substrates of the invention. Also provided is a fusion protein capable of forming a stable bond with a substrate and cells which express the fusion protein.
US08742079B2 Saccharide-containing protein conjugates and uses thereof
Conjugates of a saccharide and a biomolecule, covalently linked therebetween via a non-hydrophobic linker and methods of preparing same are disclosed. Also disclosed are medical uses utilizing such conjugates. Glycosylation reagents for use in preparing these conjugates are also disclosed. Glycosylated proteins, characterized by improved performance, are also disclosed.
US08742077B2 Method for preparing 1,6:2,3-dianhydro-β-D-mannopyranose
The invention relates to a method for preparing 1,6:2,3-dianhydro-â-D-mannopyranose and is characterized in that it includes a step of cyclizing the compound C, where R is an alykyl group and R′ is an activating agent, in an alcohol/alcoholate mixture under anhydrous conditions.
US08742076B2 Nemorubicin metabolite and analog reagents, antibody-drug conjugates and methods
The present invention relates to antibody-drug conjugate compounds of Formula I: Ab-(L-D)p  I where one or more nemorubicin metabolite or analog drug moieties (D) are covalently attached by a linker (L) to an antibody (Ab) which binds to one or more tumor-associated antigens or cell-surface receptors. These compounds may be useful in methods of diagnosis or treatment of cancer, and other diseases and disorders.
US08742059B2 Polymer precursor, high transparency polyimide precursor, polymer compound, resin composition and article using thereof
A polymer precursor including a part which sequences an unsaturated bond having a π electron orbit and a single bond alternately is disclosed. The polymer precursor has a first functional group and a second functional group which form a repeating unit constituting a polymer skeleton of an end product by an intramolecular reaction. At least a part of a conjugated state formed by the π electron orbit in the molecule is disconnected or weakened due to a three-dimensional structure of the molecule and a transmittance with respect to an electromagnetic wave of at least one wavelength selected from the group consisting of 436 nm, 405 nm, 365 nm, 248 nm and 193 nm is improved.
US08742049B2 Long chain-branched ethylene-alpha olefin copolymer
The present invention relates to an ethylene-alpha olefin copolymer comprising long chain branches (LCB), while having a narrow molecular weight distribution. The ethylene-alpha olefin copolymer can be prepared by a continuous solution polymerization process using an activated catalyst composition containing a Group 4 transition metal compound having a monocyclopentadienyl ligand, to which a quinoline amino group is introduced.
US08742048B2 Two-part, cyanoacrylate /cationically curable adhesive systems
Two part cyanoacrylate/cationically curable adhesive systems, are provided.
US08742042B2 Process for the preparation of ethylene copolymers
A polymerization process comprising contacting under polymerization conditions ethylene and at least one alpha olefin of formula CH2=CHA wherein A is a C2-C20 alkyl radical to obtain a copolymer containing from 95% by mol to 50% by mol of ethylene derived units in the presence of a catalyst system obtainable by contacting: b) at least a metallocene compound of formula (I) b) alumoxane or a compound capable of forming an alkyl metallocene cation; and optionally c) an organo aluminum compound; wherein the groups R1-R4, L, M and W are described in the text.
US08742038B2 Resist composition for immersion exposure, method of forming resist pattern using the same, and fluorine-containing compound
A resist composition for immersion exposure, including a base component (A) that exhibits changed solubility in an alkali developing solution under action of acid, an acid generator component (B) that generates acid upon exposure, and a fluorine-containing compound (C) represented by a general formula (c-1) shown below that is decomposable in an alkali developing solution: wherein R1 represents an organic group which may contain a polymerizable group, with the proviso that said polymerizable group has a carbon-carbon multiple bond, and the carbon atoms forming the multiple bond are not directly bonded to the carbon atom within the —C(═O)— group in general formula (c-1); and R2 represents an organic group having a fluorine atom.
US08742036B2 Catalyst metering device
The invention relates to a catalyst metering device with a valve formed of an iron-based alloy steel hardened to a Rockwell hardness C of at least 60. The device can be used for metering of a catalyst for an ethylene polymerization reaction. The invention further relates to ethylene polymerization wherein the catalyst is metered in a catalyst metering device with a iron-based alloy steel hardened valve, as well as to a ethylene polymerization reactor comprising such a catalyst metering device.
US08742035B2 Method of controlling a polymerization reactor
Embodiments of the invention provide a method of controlling a gas-phase polymerization process. The method includes determining a difference between a control variable of the polymerization process, such as the production rate, and the desired value of the control variable; adjusting or maintaining a first manipulated variable to at least partially compensate for the difference between the control variable and the desired value; and adjusting or maintaining a second manipulated variable to at least partially compensate for the effect of adjusting or maintaining the first manipulated variable. The first and second manipulated variables can include process variables such as the fluidized bed weight, the catalyst concentration, the concentration of one or more monomers, the flow of one or more comonomers, the ratio of one comonomer to another comonomer, the activator concentration, the ratio of an activator to selectivity control agent, the concentration of a chain transfer agent, and the retardant concentration.
US08742033B2 Method of stabilizing resorcinol resins and gel compositions made therefrom
A method of stabilizing a resorcinol-aldehyde resin comprises heating a resorcinol-aldehyde resin in the substantial absence of an acid or base catalyst at a temperature from about 130° C. to about 180° C. for a sufficient amount of time to render the resin stable in an aqueous solution, wherein the resorcinol-aldehyde resin prior to heating is a novolak resin. The stabilized resins have many useful applications. For example, they can be used to make aerogels and xerogels. They also can be used to make dipping solutions to improve the adhesion between rubber and tire cords in a tire, belt, or hose.
US08742030B2 Polyamine polyamidoamine epihaloohydrin compositions and processes for preparing and using the same
Compositions of and processes for preparing a polyamine-polyamidoamine-epihalohydrin resin generally include reacting a first polyamine, a polyamidoamine, and an epihalohydrin to form the polyamine-polyamidoamine-epihalohydrin (PPAE) resin, wherein the polyamidoamine is prepared by reacting a polycarboxylic acid or a polycarboxylic acid derivative with a second polyamine to form the polyamidoamine, wherein a molar ratio of the polyamine to the polycarboxylic acid is 1.05 to 2.0. The PPAE resin can be used in an adhesive formulation for use in creping applications for forming paper products such as tissue products.
US08742029B2 Copolyester blends with improved melt strength
Blends comprising 65-95 wt % poly(trimethylene terephthalate-co-sebacate), 5 to 35 wt % polylactic acid and a chain extender are provided that exhibit greatly increased melt strength compared to that of poly(trimethylene terephthalate-co-sebacate) alone. Such improvements allow these compositions to be processed readily by melt-blowing, which is useful for packaging and for preparing items such as biodegradable garbage bags.
US08742026B2 Process for producing water-absorbing polymer particles with improved permeability
The invention relates to a process for producing water-absorbing polymer particles with improved permeability, comprising the steps of polymerization, drying, grinding, classification and thermal surface postcrosslinking, with pneumatic conveying between grinding and classification.
US08742018B2 High Tg epoxy systems for composite applications
A thermoset resin, including the reaction product of: an epoxy resin mixture including at least one cycloaliphatic epoxy resins; a cycloaliphatic anhydride hardener; and a catalyst; wherein the reaction product has a glass transition temperature greater than or equal to 210° C. Also disclosed is a process for forming a thermoset resin, including: admixing two or more epoxy resins and a cycloaliphatic anhydride hardener to form a curable composition, wherein the epoxy resins include at least one cycloaliphatic epoxy resin; thermally curing the curable composition at a temperature of at least 150° C. to result in a thermoset resin having a glass transition temperature of at least 210° C. Such curable compositions may include: 35 to 65 weight percent of an epoxy resin mixture having at least one cycloaliphatic epoxy resins; 35 to 65 weight percent of a cycloaliphatic anhydride hardener; and from greater than 0 to 10 weight percent of a catalyst.
US08742017B2 Antistatic agent and resin composition containing same
There is provided an antistatic agent that preserves its antistatic property for a long period of time and has the appearance and the transparency that are not impaired when kneaded into a resin, and a resin composition containing the antistatic agent. An antistatic agent including a block copolymer which is obtained from a reaction product of a polyolefin (a) having one end being acid-modified and a diol and/or a diamine (b) having a polyoxyalkylene chain, and in which a part or all of acid groups remaining in the reaction product is neutralized with an alkaline substance. A thermoplastic resin composition including the antistatic resin. A film or sheet including the thermoplastic resin composition.
US08742016B2 Method for producing carboxylated ethylene polymer blends
Procedure for the manufacture of carboxylated ethylene polymer blends, in which in a 1st step, in a fluid mixing reactor, to 100 pbw of a particulate ethylene polymer—chosen from among ethylene homopolymers (HDPE, LDPE) and/or linear ethylene copolymers with 2 to ≦20 wt.-% polymerized-in C3-12-olefin units (LLDPE, EOP), with a melt-flow rate MFR (190° C./2.16 kg)≧20 g/10 min—are added 0.05-15 pbw of a α,β-ethylenically unsaturated mono and/or dicarboxylic acid or its anhydride (carboxyl monomer), or a monomer mixture containing at least one carboxyl monomer and 0.01-10 pbw of a radical initiator or initiator mixture, and graft-polymerizing at reaction temperatures of 30-120° C., over a reaction time of 5-120 min and subsequently, in a 2nd step, reacting a mixture continuously fed into a reaction extruder of 100 pbw of the modified ethylene polymer obtained in the 1st solid phase step, 150-4,000 pbw of an ethylene polymer or polymer blend with a melt flow rate MFR (190° C., 2.16 kg)<20 g/10 min, as well as 0-4,000 pbw of an olefinic elastomer, at temperatures of 160-260° C. and continuously removing the graft-modified ethylene polymer blend that has a degree of carboxylation of 0.05-1 wt.-%. The products obtained are especially suitable as adhesion promoters and/or adhesives for numerous substrates, preferably on and between metallic surfaces.
US08742014B2 Liquid resin composition and cured product using the liquid resin composition
An object of the invention is to provide a liquid resin composition with low viscosity while containing polymer particles. Further, another object of the invention is to provide a liquid resin composition containing a large quantity of polymer particles without increasing the viscosity of the liquid resin composition. A liquid resin composition of the invention is comprising a liquid resin component and polymer particles each having an elastic core layer, an intermediate layer formed with a monomer having two or more double bonds and coated on the core layer, and a shell layer coated on the intermediate layer; wherein the polymer particles are dispersed at a ratio of their volume average particle diameter (Mv) to their number average particle diameter (Mn) of 3 or lower.
US08742013B2 Synthesis of lipoamide-grafted high molecular compound and method therefor
The present disclosure provides polymer compounds binding with lipoamide produced by the reaction of the primary amine group of lipoamide with the carboxy group of polysaccharide compounds such as chondroitin sulfates, carboxymethyl celluloses, or hyaluronic acids; functional compounds such as peptides, proteins, growth factors; or drugs; or biocompatible polymers such as poly(ethylene oxide), poly(vinyl alcohol), or poly(vinyl pyrrolidone). The present disclosure also provides their synthesis methods, products of hydrogels and films using the same as and methods for manufacturing the products.
US08742012B2 Thermosetting film-forming compositions that produce atrane-containing cured coatings
The invention includes a thermosetting film-forming composition comprising a polytrialkanolamine reacted with a crosslinking agent composition. The composition forms a three-dimensional crosslinked network having atrane-containing linkages.
US08742009B2 Temporary adhesive composition, and method of producing thin wafer
A temporary adhesive for which temporary adhesion is simple and subsequent detachment is also simple, meaning productivity can be improved. Also, a method of producing a thin wafer that uses the temporary adhesive. The temporary adhesive composition comprises: (A) an organopolysiloxane comprising: (I) 40 to 99 mol % of siloxane units represented by R1SiO3/2 (T units), (II) 0 to 49 mol % of siloxane units represented by R2R3SiO2/2 units (D units) and (III) 1 to 25 mol % of siloxane units represented by R4R5R6SiO1/2 units (M units) (wherein each of R1 to R6 represents an unsubstituted or substituted monovalent hydrocarbon group of 1 to 10 carbon atoms), and having a weight-average molecular weight exceeding 2,000, and (B) an organic solvent having a boiling point of not more than 220° C.
US08742008B2 Process for preparing siloxane-based compositions and derivative compositions thereof
A process for forming a new group of siloxane-based compositions by a one-step co-hydrolysis and the compositions formed thereof. The siloxane-based compositions being functionalized with a carbon-carbon double (C═C) bond and a silicon-hydrogen (Si—H) bond. The C═C bond and hydrogen (H) each being attached directly to a silicon (Si) atom of the silicon-oxygen (Si—O) backbone of the siloxane-based composition. The C═C bond may be from a vinyl or an aromatic radical like a phenyl substituent. The C═C bond substituent provides the functionality needed for forming crosslinkages through standard dehydrocoupling catalysts without the need for siloxane fluids or organic compounds containing alkyl or aryl functional groups. The process provides for varying proportions of silanes as starting monomers to tailor the desired silicon, carbon, hydrogen and oxygen ratios in the siloxane-based compositions or resins. The siloxane-based compositions may be used as precursors or replacement resins in the fabrication of other materials.
US08742007B2 Color developing colorless primer
The intense purple dye normally found in purple primers for use in the adhesive bonding of plastics is replaced with a leuco dye capable developing a visually intense color when activated through contact with the particular plastic being bonded or a complementary solvent cement.
US08742006B2 Cross-linkable nitrile rubber composition and cross-linked rubber
A cross-linkable nitrile rubber composition comprising a nitrile rubber (A1) including an α,β-ethylenically unsaturated nitrile monomer unit and having iodine value of 120 or less, silica (B1) having CaO value determined by X-ray fluorescence composition analysis of 0.5 wt % or more, and a crosslinking agent (C1). According to the present invention, a cross-linkable nitrile rubber composition, capable of giving a highly-saturated cross-linked nitrile rubber having excellent mechanical properties such as elongation and small compression set, and excellent in workability, and a cross-linked rubber obtained by crosslinking the rubber composition can be provided.
US08742004B1 Coating system having long-term durability and chemical resistance
A highly durable coating composition particularly suited for use on printed articles requiring protection from exposure to the natural elements, chemical exposure, or abrasion. The coating composition generally comprises a fluoropolymer resin, an acrylic polyol resin and a melamine resin. Optionally, a polyisocyanate crosslinking agent may also be included to accelerate curing of the coating.
US08742002B2 Release coating with low friction coefficient
A composition of a release coating, for furnishing a release liner with a layer of the release coating, has a release agent and 0.01% by weight to 30% by weight (based on the overall composition) of a finely particulate additive in the form of three-dimensional bodies based on polymers prepared from vinyl building blocks.
US08742001B2 Nanocomposite material containing polymer binders
The invention relates to a nanocomposite material that contains a polymer binder, a filler and a fraction of nanoparticles, characterized in that the fraction of nanoparticles comprises multi-layered carbon particles having a toroid-like shape with a size of 15 to 150 nm, wherein the ratio between the outer diameter and the thickness of the toroid body is in a range of (10-3):1. This nano-modification makes it possible to obtain an efficient compaction and hardening of the nanocomposite material close to the filler/binder inter-phase barrier, and accordingly to increase the average density, elasticity, hardness and resistance of the material. The invention can be used for making various parts and articles for use in mechanical engineering and transport, including instrument holders for the precise surface treatment of parts.
US08741998B2 Thermally conductive and electrically insulative polymer compositions containing a thermally insulative filler and uses thereof
Disclosed herein are compositions comprising a. from 35 to 80 vol % of a thermoplastic polymer; b. from 5 to 45 vol % of a thermally insulative filler with an intrinsic thermal conductivity less than or equal to 10 W/mK; and c. from 5 to 15 vol % of a thermally conductive filler with an intrinsic thermal conductivity greater than or equal to 50 W/mK, wherein the composition is characterized by: i. a thermal conductivity of at least 1.0 W/mK; ii. a thermal conductivity of at least 7 times the total filler volume fraction times the thermal conductivity of the pure thermoplastic polymer; and iii. a volume resistivity of at least 107 Ohm·cm. Also disclosed are articles and methods of use therefor.
US08741997B2 Use of amphiphilic copolymers as agents for improving the thermal stability and UV resistance of chlorinated and filled thermoplastic materials, process for the fabrication of the said materials
The present invention consists of the use, in a chlorinated and filled thermoplastic composition containing at least one chlorinated thermoplastic resin and at least one mineral filler, as an agent improving the thermal stability and UV resistance of the said composition, of a linear amphiphilic copolymer characterized in that: it consists of at least one hydrophilic monomer and at least one hydrophobic monomer, it has an average molar mass by weight of between 5,000 g/mol and 20,000 g/mol and a polymolecularity index less than or equal to 3, and preferentially an average molar mass by weight of between 10,000 g/mol and 15,000 g/mol, and a polymolecularity index less than or equal to 2.5. It also concerns a manufacturing process for a chlorinated and filled thermoplastic composition implementing the said copolymer, as well as the composition obtained directly by the said process.
US08741995B2 Surface-treated calcium carbonate and paste-like resin composition containing same
A calcium carbonate having a surface treated with a surface treating agent containing a sodium salt or a potassium salt of a fatty acid, the surface treating agent containing a sodium salt or a potassium salt of palmitic acid in an amount of PW in terms of acid, the surface treating agent containing a sodium salt or a potassium salt of stearic acid in an amount of SW in terms of acid, a total amount of PW and SW being PW+SW≧90, a ratio of PW to SW being 0.30≦PW/SW≦1.1, the surface-treated calcium carbonate having a BET specific surface area of SA2 of 15≦SA2≦48, and the sodium salt or the potassium salt of the fatty acid being used for the treatment in an amount of FA and a ratio (FA/SA2) being 0.095≦FA/SA2≦0.135.
US08741990B2 Adhesive composition
The invention relates to an adhesive composition comprising hydrophilic silicone elastomers and hydrophobic silicone elastomers and optionally water absorbent material, wherein the ratio between the hydrophilic silicone elastomers and the hydrophobic silicone elastomers is from 95:5 to 5:95. The adhesive is suited for medical use due to its skin-friendliness. The invention further relates to a medical device comprising said adhesive composition.
US08741989B2 Incorporation of a resin dispersion to improve the moisture resistance of gypsum products
This invention relates to a composition suitable for use in making moisture resistant gypsum products. In particular, this invention relates to resin dispersions and their use in combination with gypsum to form moisture resistant gypsum compositions which are settable by hydration. Further, the invention relates to moisture resistant products formed from such settable gypsum compositions, e.g. panels and boards, and a method for the manufacture of such moisture resistant gypsum products.
US08741986B2 Methods and devices for continuous production of polymeric dispersions
The present invention is directed to the use of continuous extrusion devices to form high quality polymer dispersions. Screw extruder devices of the present invention inject water into a zone of high pressure, temperature, and shear to cause the rapid inversion of a weld in less than, for example, one minute, which compares very favorably with conventional batch methods, which can take, for example, two or more hours to complete an inversion. This rapid inversion—a surprising result given the extended time inversion requires in batch processes—allows for the continuous production of polymer dispersions.
US08741985B2 Resin emulsion for sealer
A resin composition for sealers as well as a resin composition for sealers and a paint composition for sealers that contains the resin composition for sealers are useful for sealers to be used with such inorganic building materials as ceramic-based building materials. The resin emulsion for sealers is a resin emulsion which contains emulsion particles having an inner layer and an outer layer. The inner layer is formed with a polymer which is formulated by means of emulsion polymerization of a monomer component containing styrene and a monomer other than the styrene, and the outer layer is formed with a polymer which is formulated by means of emulsion polymerization of a monomer component containing a carboxyl-group-containing monomer and a monomer other than the carboxyl-group-containing monomer.
US08741984B2 Aqueous ink, ink jet recording method, ink cartridge, recording unit and ink jet recording apparatus
The invention provides an aqueous ink comprising a polymer having hydroxyl groups and a pigment, which can provide images excellent in scratch resistance and highlighter resistance and can inhibit the seeping out phenomenon of the polymer and the deterioration of ejection characteristics even when it is stored for a long period of time. The aqueous ink comprises a polymer having hydroxyl groups, a pigment and a water-soluble organic solvent, wherein the water-soluble organic solvent comprises a polyhydric alcohol having a value of number of hydroxyl groups/number of carbon atoms in its molecule of 0.50 or less.
US08741980B2 Hardenable two part acrylic composition
A hardenable two part acrylic composition, a polymer component of the two part hardenable composition and a method of producing a polymer component of the two part composition are disclosed. The hardenable two part acrylic composition includes an acrylic polymer composition first part and an acrylic monomer composition second part. The acrylic polymer composition first part includes a first type of acrylic polymer particles wherein each first type of acrylic polymer particle is formed of a network of coalesced emulsion polymerized acrylic microparticles or is macroporous. The acrylic polymer composition may include emulsion polymerised acrylic polymer particles of particle size between 10 and 2000 nm and includes the use of acrylic polymer particles formed of a network of coalesced emulsion polymerized acrylic microparticles as a dough time reduction agent in a hardenable two part acrylic composition.
US08741978B2 Prepregs and cured in place solid surfaces prepared therefrom
A prepreg which is capable of being cured-in-place into a solid surface by irradiation, heating or a combination of the two is prepared. The cured-in-place solid surfaces can be used as veneer cladding for rigid substrates such as floor and wall tiles, kitchen and bath counter tops, sinks, cabinet door veneers, bath surrounds, architectural surfaces such as columns and roofs and the like.
US08741976B2 Process for producing aerogels or xerogels
A process for producing porous aerogels or xerogels includes a reaction of at least one polyfunctional isocyanate with an amine component. The amine component includes at least one polyfunctional substituted aromatic amine. The reaction is in the presence of a solvent and a catalyst. Aerogels and xerogels that can be obtained in this way can be used as insulation material and in vacuum insulation panels.
US08741974B2 Method of forming filter in fluid flow path in microfluidic device
A method for forming a filter in a fluid flow path in a microfluidic device is provided. The method includes introducing a photopolymerization reaction solution into the microfluidic device; and performing polymerization of photopolymerization reaction solution to form a filter in the fluid flow path in a microfluidic device.
US08741959B2 Paracetamol for parenteral administration
The invention relates to an aqueous pharmaceutical composition, preferably an infusion solution, for parenteral administration which contains paracetamol and has an electrical conductivity of not more than 200 μS cm−1.
US08741951B2 Non-steroidal compounds for androgen receptor modulation
The present invention concerns compounds of general Formula (I): method of preparation and uses thereof.
US08741947B2 Biologically active macrolides, compositions, and uses thereof
The present invention provides a compound of the formula (I) or (II, wherein R1 is H, alkyl, alkenyl or aryl, R2 is H, alkyl or aryl, R3 is H, a alkyl, alkenyl or aryl, R4 and R4-R8 are independently R10, C(O)R10 or SO2R10, wherein R10 is H, alkyl, alkenyl or aryl, and R9 is R9a, C(O)R9a or SO2R9a, wherein R9a is H, alkyl, alkenyl or aryl. R9a can be unsubstituted or substituted with one or more oxo(═O), OR9b, OC(O)R9b, OSO2R9b, NHR9b, NHC(O)R9b and NHSO2R9b groups. R9b is H, alkyl, alkenyl, or aryl. R9b can be unsubstituted or substituted with one or more groups such as oxo(═O), OR9c, CO2R9c, CO2R9c and OC(O)R9c. R9c is H, or a unsubstituted or substituted alkyl, alkenyl or aryl. The present invention further provides a composition comprising at least one compound of the present invention and a pharmaceutically acceptable carrier, alone or in combination with at least one additional active agent. The present invention further provides a method of treating a condition treatable by the inhibition of vacuolar-type (H+)-ATPase and a method of treating cancer.
US08741946B2 Inhibitors of flaviviridae viruses
Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections (e.g. hepatitis C infections), particularly drug resistant Flaviviridae virus infections.
US08741942B2 Inhibitors of cellular necrosis
The present invention relates to compounds and pharmaceutical preparations and their use in therapy for preventing or treating trauma, ischemia, stroke and degenerative diseases associated with cell death. Methods and compositions of the invention are particularly useful for treating neurological disorders associated with cellular necrosis.
US08741935B2 Nicotine delivery product and method for producing it
A nicotine delivery product comprising the reaction product of a nicotine/cation exchange resin complex and an organic polyol; and a method for preparing it comprising (a) mixing an aqueous suspension of a nicotine/cation exchange resin complex with an organic polyol or an aqueous solution thereof, and (b) removing water from the mixture to produce said nicotine delivery product. The nicotine delivery product has a nicotine release rate of at least 80% over a 10 minute period. It is particularly suited for use in smoking substitution devices delivering nicotine such as chewing gum, patches, lozenges, melting tablets and tablets for chewing.
US08741934B2 Inhibitors of ion channels
The invention is directed to compounds of Formula I in which: R5, R6, B and Z are defined supra.
US08741928B2 Protected antimicrobial compounds for high temperature applications
Provided are protected antimicrobial compounds which are useful for controlling microorganisms in aqueous or water-containing systems, such as oil or gas field fluids, at elevated temperature. The antimicrobial compounds are of the formula I: wherein R, R1, R2, X and Y are as defined herein.
US08741925B2 Modulators of ATP-binding cassette transporters
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
US08741924B2 Compounds and methods for treatment of systemic lupus erythematosus
Small molecule compounds are provided for treating lupus as are methods of treating lupus using these compounds.
US08741921B2 N-(imidazolidin-2-ylidene)-heterocyclopenta[b]pyridine derivatives as modulators of alpha 2 adrenergic receptors
The present invention relates to novel N-(imidazolidin-2-ylidene)-heterocyclo penta[b]pyridine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.
US08741914B2 Antiviral compounds and uses thereof
This invention relates to: (a) compounds and salts thereof that, inter alia, inhibit HCV; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; (e) methods of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and compositions.
US08741912B2 Deazapurines useful as inhibitors of Janus kinases
The present invention relates to compounds useful as inhibitors of protein kinases, particularly of JAK family kinases. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The compounds are generally represented by structural formula I or pharmaceutically acceptable salts thereof:
US08741911B2 Raf inhibitor compounds
The present invention provides a pyrido[2,3-d]pyrimidine compound, or a pharmaceutically acceptable salt thereof, that inhibits Raf and, therefore, may be useful in treating cancer.
US08741908B2 Inhibitors of bruton's tyrosine kinase
Disclosed herein are compounds that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk, such as those having the structure of Formula (B) Methods for the preparation of the compounds are disclosed. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.
US08741907B2 Alkyl-substituted pyrazolopyrimidines
The invention relates to alkyl-substituted pyrazolopyrimidines, process for their preparation, and the use thereof for producing medicaments for improving learning and/or memory. The alkyl-substituted pyrazolopyrimidines are of the formula (I): with the variables as defined in the claims.
US08741901B2 Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
The compounds of the present invention are represented by the chemical structure found in Formula (I): wherein: the carbon atom designated * is in the R or S configuration; and X is a fused bicyclic carbocycle or heterocycle selected from the group consisting of benzofuranyl, benzo[b]thiophenyl, benzoisothiazolyl, benzoisoxazolyl, indazolyl, indolyl, isoindolyl, indolizinyl, benzoimidazolyl, benzooxazolyl, benzothiazolyl, benzotriazolyl, imidazo[1,2-a]pyridinyl, pyrazolo[1,5-a]pyridinyl, [1,2,4]triazolo[4,3-a]pyridinyl, thieno[2,3-b]pyridinyl, thieno[3,2-b]pyridinyl, 1H-pyrrolo[2,3-b]pyridinyl, indenyl, indanyl, dihydrobenzocycloheptenyl, tetrahydrobenzocycloheptenyl, dihydrobenzothiophenyl, dihydrobenzofuranyl, indolinyl, naphthyl, tetrahydronaphthyl, quinolinyl, isoquinolinyl, 4H-quinolizinyl, 9aH-quinolizinyl, quinazolinyl, cinnolinyl, phthalazinyl, quinoxalinyl, benzo[1,2,3]triazinyl, benzo[1,2,4]triazinyl, 2H-chromenyl, 4H-chromenyl, and a fused bicyclic carbocycle or fused bicyclic heterocycle optionally substituted with substituents (1 to 4 in number) as defined in R14; with R1, R2, R3, R4, R5, R6, R7, R8, and R14 defined herein.
US08741898B2 Polycyclic heteroaryl substituted triazoles useful as Axl inhibitors
Polycyclic heteroaryl substituted triazoles and pharmaceutical compositions containing the compounds are disclosed as being useful in inhibiting the activity of the receptor protein tyrosine kinase Axl. Methods of using the compounds in treating diseases or conditions associated with Axl activity are also disclosed.
US08741895B2 Pyrrolo[2,3-b]pyridin-4-yl-amines and pyrrolo[2,3-b]pyrimidin-5-yl-amines as Janus kinase inhibitors
The present invention provides pyrrolo[2,3-b]pyridine-4-yl amines pyrrolo[2,3-b]pyrimidin-4-yl amines that modulate the activity of Janus kinases and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases and cancer.
US08741894B2 Arylsulfonamide CCR3 antagonists
Provided herein are arylsulfonamides that are useful for modulating CCR3 activity, and pharmaceutical compositions thereof. Also provided herein are methods of their use for treating, preventing, or ameliorating one or more symptoms of a CCR3-mediated disorder, disease, or condition.
US08741891B1 N-substituted noribogaine prodrugs
This invention relates generally to prodrugs of noribogaine. This invention also relates to pharmaceutical compositions comprising the prodrugs of noribogaine as well as method of treating pain, addiction and/or stress using such compounds and/or pharmaceutical compositions.
US08741888B2 Sleep aid composition and method
A sleep composition including zolpidem and quetiapine in combination provides a healthy sleep pattern allowing the user to get seven or eight hours sleep. The amount of each ingredient in the combination is lower than the amount usually needed to provide this amount of sleep when the ingredients are being used alone.
US08741887B2 Azetidinyl diamides as monoacylglycerol lipase inhibitors
Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula (I) as follows: wherein Y, Z, R1, and s are defined herein.
US08741886B2 Baclofen and acamprosate based therapy of neurological disorders
The present invention relates to combinations and methods for the treatment of neurological disorders related to glutamate excitotoxicity and Amyloid β toxicity. More specifically, the present invention relates to novel combinatorial therapies of Multiple Sclerosis, Alzheimer's disease, Alzheimer's disease related disorder, Amyotrophic Lateral Sclerosis, Parkinson's disease, Huntington's disease, neuropathic pain, alcoholic neuropathy, alcoholism or alcohol withdrawal, or spinal cord injury, based on Baclofen and Acamprosate combination.
US08741884B2 Compounds for the treatment of hepatitis C
The disclosure provides compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.
US08741882B2 Anti-diabetic compounds
The preset invention relates to a new oral anti-diabetic compound prepared by synthesizing a steroid and a guanide or biguanide, which is eliminated via the hepatic route, instead of the renal route, to avoid adverse effects of administering metformin in diabetic patients with renal dysfunction. A pharmaceutical composition comprising the compound of the invention and the method for treating diabetes using the compound are also provided.
US08741881B2 Testosterone gel and method of use
The present invention relates to an improved transdermal hydroalcoholic testosterone gen formulation that provides, among other things, a desirable pharmacokinetic hormone profile, and methods of use.
US08741879B2 Petroleum jelly-free unguent compositions comprising vitamin D compounds and optionally steroidal anti-inflammatory agents
Novel compositions in petroleum jelly-free unguent form, in particular for topical application, contain a vitamin D compound and optionally an active agent of the family of steroidal anti-inflammatory agents.
US08741877B2 Polylactides compositions and uses thereof
The present invention provides compositions and methods relating to polylactides which may be used for drug delivery (e.g., parenteral delivery), wherein an organic solvent is not required.
US08741875B2 Compounds as receptor modulators with therapeutic utility
The present invention relates to novel amine derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
US08741872B2 Self-gelling alginate systems and uses thereof
Kits and compositions for producing an alginate gel are disclosed. The kits and compositions comprise soluble alginate and insoluble alginate/gelling ion particles. Methods for dispensing a self-gelling alginate dispersion are disclosed. The methods comprise forming a dispersion of insoluble alginate/gelling ion particles in a solution containing soluble alginate, and dispensing the dispersion whereby the dispersion forms an alginate gel matrix. The methods may include dispensing the dispersion into the body of an individual. An alginate gel having a thickness of greater than 5 mm and a homogenous alginate matrix network and homogenous alginate gels free of one or more of: sulfates citrates, phosphates, lactates, EDTA or lipids are disclosed. Implantable devices comprising a homogenous alginate gel coating are disclosed. Methods of improving the viability of pancreatic islets, or other cellular aggregates or tissue, following isolation and during storage and transport are disclosed.
US08741871B2 Trehalose compound, method for producing same, and pharmaceutical product containing the compound
A trehalose compound having high immunopotentiating activity and low toxicity is represented by formula (1). (In the formula, X and X′ each represents a phenyl, a naphthyl, R1—CHR1— (wherein R1 and R2 each represents a C7-C21 alkyl group or the like) or the like; and n and n′ each independently represents an integer of 0-3). The compound exhibits a high activating effect on macrophages and neutrophils.
US08741870B2 Axl receptor tyrosine kinase aptamer inhibitor for use in therapy
The present invention concerns a nucleotide aptamer having the sequence: 5′-AUGAUCAAUCGCCUCAAUUCGACAGGAGGCUCAC-3′(SEQ ID NO: 1) for use in the treatment and/or prevention and/or diagnosis of an Axl receptor tyrosine kinase induced disorder and a pharmaceutical composition comprising the same. The invention also relates to a method for the diagnosis of an Axl receptor tyrosine kinase induced disorder in a patient from which a sample is obtained and related diagnostic kit.
US08741859B2 Fungicide composition for agriculture and horticulture and method for preventing plant diseases
The present invention provides a composition in which a fungicidal effect against a cultivated crop infected by a plant disease is stable and highly active. An excellent agricultural or horticultural fungicide composition for controlling a plant disease is provided by using (a) at least one imidazole compound represented by formula (I): wherein R represents a C1-6 alkyl group or a C1-6 alkoxy group; and n represents an integer of 1 to 5 and (b) polyoxins as active ingredients; by combination as compared to a single use of each compound, and a plant disease is thereby controlled.
US08741857B1 Treatments for actinic keratoses
A composition of gentamicin and colchicine in a dermatologically acceptable cream base provided improved clearance of actinic keratoses following topical application for 1 to 3 months. The composition provides improved clearance of recalcitrant actinic keratoses. Furthermore, the treatment causes less pain and irritation than other topical treatments for actinic keratoses.
US08741854B2 Compositions and methods for feeding poultry
Feed supplements for poultry raised using a rapid growth regimen are disclosed herein. The supplements include D-ribose in an amount effective to improve the resistance to cardiomyopathy in the poultry. Methods for feeding poultry are also disclosed herein.
US08741852B2 Peptides having antimicrobial activity
Disclosed herein is a peptide for inhibiting growth of bacterial pathogens in a biological sample, characterized by an amino acid sequence selected from a group consisting of Gly-Leu-Phe-Asp-Lys-Trp-Ala-Trp-Trp-Arg-Trp-Arg-Arg (SEQ ID NO:1), Gly-Leu-Phe-Asp-Ile-Trp-Ala-Trp-Trp-Arg-Trp-Arg-Arg (SEQ ID NO:2), Gly-Leu-Phe-Asp-Ile-Trp-Lys-Trp-Trp-Arg-Trp-Arg-Arg (SEQ ID No:3), Gly-Leu-Phe-Asp-Ile-Trp-Lys-Lys-Trp-Arg-Trp-Arg-Arg (SEQ ID NO:4), and Gly-Leu-Phe-Asp-Ile-Trp-Lys-Lys-Leu-Arg-Trp-Arg-Arg (SEQ ID NO:5).
US08741851B2 Peptides having antimicrobial activity
Disclosed herein is a peptide for inhibiting growth of bacterial pathogens in a biological sample, characterized by an amino acid sequence selected from a group consisting of Pro-His-Trp-Trp-Lys-Trp-Ala-Trp-Trp-His-His-Arg-Arg (SEQ ID NO:1), Lys-His-Trp-Trp-Lys-His-Asp-Trp-Trp-Arg-Trp-Arg-Arg (SEQ ID NO:2), and Ile-Leu-Trp-Trp-Leu-Leu-Ala-Trp-Trp-Arg-Trp-Pro-His (SEQ ID NO:3).
US08741850B2 Compounds modulators of VEGF activity and uses thereof
Compounds of general formula (1): X1Y1X2Y2X3Y3X4Y4Y5X5X6Y6X7Y7X8X9X10 wherein X1-X10 are any natural or unnatural amino acids and Y1 is Gln; Y2 is Met or Leu; Y3 is He; Y4 is Pro or Ser; Y5 is His or Gly; Y6 is Gln or Pro; Y7 is He or Tyr or their homolog or ortolog are described; these compounds are able to bind to the VEGF receptors and to modulate the angiogenesis mediated by the VEG.
US08741847B2 Agent and methods for reducing inflammatory markers
A method for treating an autism spectrum condition includes administering an effective dose of a TNF-α inhibiting agent to a person having an autism spectrum condition or pervasive development disorder and at least one of elevated TNF-α in the cerebrospinal fluid or elevated TNF-α in the serum, as compared to normal conditions; and lowering at least one of the elevated TNF-α in the cerebrospinal fluid or elevated TNF-α in the serum. A TNF-α inhibiting agent includes at least one of Lenalinomide; Thalidomide; L-Carnosine; Infliximab; Etanercept; a stem cell preparation; derivatives thereof, isomers thereof, or pharmaceutically acceptable salts thereof.
US08741846B2 Storage-stable, functionally intact fibrinogen
Method for the production of a fibrinogen solution from an aqueous solution that contains functionally intact fibrinogen and is contaminated with profibrin and/or fibrin monomers and/or fibrin monomer complexes and/or fibrin split products, characterized in that the contaminations are precipitated using a non-denaturing precipitating agent at a temperature ranging from −4° to +4° and calcium ion activity not exceeding that of a 1,000 μM CaCl2 solution and are separated from the solution by means of filtering or centrifugation process.
US08741844B2 Use of mutated antithrombins for treating or preventing coagulation disorders
Use of a mutated antithrombin having substantially no activity, in particular no anticoagulant activity, possibly in association with an anticoagulant, for the preparation of a drug intended for the prevention or treatment of pathologies linked to or associated with coagulation disorders.
US08741838B2 Control of growth and repair of gastro-intestinal tissues by gastrokines and inhibitors
A novel group of gastrokines called Gastric Antrum Mucosal Protein is characterized. A member of the group is designated AMP-18. AMP-18 genomic DNA, cDNA and the AMP-18 protein are sequenced for human, mouse and pig. The AMP-18 protein and active peptides derived from it are cellular growth factors. Surprisingly, peptides capable of inhibiting the effects of the complete protein, are also derived from the AMP-18 protein. Cytoprotection and control of mammalian gastro-intestinal tissue growth and repair (restitution) is facilitated by the use of the proteins, making the proteins candidates for therapies in inflammatory bowel disease, mucositis, and gastric ulcers.
US08741836B2 Polypeptides
The invention relates to polypeptides comprising an amino acid sequence which is an analogue of pramlintide, pharmaceutical compositions comprising these polypeptides, and these polypeptides for use as medicaments.
US08741835B2 Use of a ghrelin agonist to improve the catabolic effects of glucocorticoid treatment
A method and pharmaceutical composition for inhibiting the effect of glucocorticoids, particularly dexamethasone, which suppress growth hormone secretion, by administering ghrelin or a ghrelin analogue, for example, H-Inp-D-Bal-D-Trp-Phe-Apc-NH2 (SEQ ID NO:73) or other suitable ghrelin agonist, to counteract the catabolic effects of dexamethasone and other natural glucocorticoids.
US08741833B2 Self-assembling peptides incorporating modifications and methods of use thereof
The invention relates to a novel class of self-assembling peptides, compositions thereof, methods for the preparation thereof and methods of use thereof. The invention also encompasses methods for tissue regeneration, increasing the production of extracellular matrix proteins, and methods of treatment comprising administering self-assembling peptides.
US08741826B2 Dimethylsulfoxide formulation in mixture with additive for lowering the crystallization point of same, and applications of said mixture
Use of at least one diol and/or of at least one triol as a dimethyl sulfoxide (DMSO) additive for lowering the crystallization point thereof. The DMSO formulation is used in combination with the abovementioned additive as a paint-stripping composition, a surface-cleaning composition, a graffiti-cleaning composition, a surface-cleaning composition in the microelectronics field, such as a photoresist stripper, a DMSO-based agrochemical composition, or as a constituent of an abovementioned composition, as a polymer-dissolving solvent, or as a constituent of a composition that is useful in the field of cosmetology or pharmacy.
US08741825B2 Hair washing composition
To provide a cleansing composition showing excellent properties during cleansing and rinsing while satisfying foam performance.The hair cleansing composition according to the invention contains the following ingredients (A), (B), (C), and (D) at a weight ratio of Ingredient (A) to Ingredient (B) [(A)/(B)] is of from 0.1 to 1.2 and at a weight ratio of Ingredient (A) to Ingredient (C) [(A)/(C)] of from 0.1 to 1.2: (A) an ether carboxylate surfactant, (B) an ether sulfate surfactant, (C) a betaine amphoteric surfactant, (D) a cationic-group containing copolymer obtained by the copolymerization of a monomer mixture containing three monomers.
US08741822B2 Esters for use as a base stock and in lubricant applications
This invention relates to base ester compounds and complex ester compounds that can be used as a base stock for lubricant applications or a base stock blend component for use in a finished lubricant or for particular applications, and methods of making the same. The base ester compounds and complex esters described herein comprise dimer and/or trimer esters, and their respective branched derivatives.
US08741821B2 Nanoparticle additives and lubricant formulations containing the nanoparticle additives
A method for reducing a friction coefficient adjacent a lubricated surface, and a lubricant composition for reducing a friction coefficient between lubricated surfaces. The method includes providing an amount of metal-containing dispersed in a fully formulated lubricant composition containing a base oil of lubricating viscosity, wherein the nanoparticles have an average particles size ranging from about 1 to about 10 nanometers. The lubricant composition containing the metal-containing nanoparticles is applied to a surface to be lubricated.
US08741819B2 Composite particles and method of forming
Composite particles and a method of forming composite particles are described. The composite particles comprise at least one inorganic nanoparticle covalently bound to at least one inorganic microparticle with a linking compound. Lubricant compositions and sprayable dispersion compositions comprising composite particles are also described.
US08741815B2 Methods and devices for amplification of nucleic acid
The present invention relates to methods and devices for amplifying nucleic acid, and, in particular, amplifying so as to generate products on a surface without the use of emulsions. In a preferred embodiment, a plurality of groups of amplified product are generated on the surface, each group positioned in different (typically predetermined) locations on said surface so as to create an array.
US08741810B2 In vitro methods of producing and identifying immunoglobulin molecules in eukaryotic cells
The present invention relates to a high efficiency method of expressing immunoglobulin molecules in eukaryotic cells. The invention is further drawn to a method of producing immunoglobulin heavy and light chain libraries, particularly using the trimolecular recombination method, for expression in eukaryotic cells. The invention further provides methods of selecting and screening for antigen-specific immunoglobulin molecules, and antigen-specific fragments thereof. The invention also provides kits for producing, screening and selecting antigen-specific immunoglobulin molecules. Finally, the invention provides immunoglobulin molecules, and antigen-specific fragments thereof, produced by the methods provided herein.
US08741801B2 Catalytic platinum and its 3d-transition-metal alloy nanoparticles
Platinum (Pt)-based alloys are effective catalysts for oxygen reduction reaction (ORR) or fuel oxidation in proton exchange membrane fuel cells (PEMFCs). A wet-chemical approach for preparing monodisperse Pt3Ni, Pt3Co and Pt3Fe nanocubes and Pt3Ni nanoctahedra which are terminated with {100} and {111} facets, respectively, were developed. Such nanoscaled electrocatalysts supported on carbon black with controlled shape, e.g., octahedral configuration, is provided. ORR activity on the Pt3Ni nanoctahedra is ˜5.1 fold higher than that of nanocubes with a similar size, and their C-supported samples are highly active with respect to commercial Pt/C.
US08741800B2 Hydrothermal performance of catalyst supports
A high surface area catalyst with a mesoporous support structure and a thin conformal coating over the surface of the support structure. The high surface area catalyst support is adapted for carrying out a reaction in a reaction environment where the thin conformal coating protects the support structure within the reaction environment. In various embodiments, the support structure is a mesoporous silica catalytic support and the thin conformal coating comprises a layer of metal oxide resistant to the reaction environment which may be a hydrothermal environment.
US08741794B2 Glass substrate for display and display
A glass substrate for a display, which is formed of a glass having a light weight and having high refinability with decreasing environmental burdens, the glass comprising, by mass %, 50 to 70% of SiO2, 5 to 18% of B2O3, 10 to 25% of Al2O3, 0 to 10% of MgO, 0 to 20% of CaO, 0 to 20% of SrO, 0 to 10% of BaO, 5 to 20% of RO (in which R is at least one member selected from the group consisting of Mg, Ca, Sr and Ba), and over 0.20% but not more than 2.0% of R′2O (in which R′ is at least one member selected from the group consisting of Li, Na and K), and containing, by mass %, 0.05 to 1.5% of oxide of metal that changes in valence number in a molten glass, and substantially containing none of As2O3, Sb2O3 and PbO.
US08741791B2 Crystallized glass with negative coefficient of thermal expansion and method for manufacturing the same
A crystallized glass with negative coefficient of thermal expansion includes 38 wt % to 64 wt % of silica (SiO2); 30 wt % to 40 wt % of alumina (Al2O3); and 5 wt % to 12 wt % of lithium oxide (Li2O) as a basic component, and further includes more than one component selected from the group consisting of 0.5 wt % to 15 wt % of zirconia (ZrO2), 0.5 wt % to 6.5 wt % of titanium dioxide (TiO2), 0.5 wt % to 4 wt % of phosphorus pentoxide (P2O5), 2 wt % to 5 wt % of magnesium oxide (MgO), and 0 wt % to 5 wt % of magnesium fluoride (MgF2) in addition to the basic components. The crystallized glass may have a high negative coefficient of thermal expansion so that it has an advantage that it can be used as a thermal expansion compensation material according to the temperatures of all kinds of glasses and similar products thereof.
US08741790B2 PTFE/fiberglass composite for use as a conveyor belt
A PTFE/fiberglass composite for use as a conveyor belt comprises a fiberglass fabric having oppositely facing surfaces. The fabric has a structure defining a substantially uniform pattern of openings extending from one to the other of its major surfaces, with the average area of the individual openings being at least about 0.20258 mm2. PTFE films are laminated to the major surfaces of the fabric. The laminated films are interconnected by fluroropolymer ties extending through the fabric openings and are adhered to the major surfaces with a peel strength of between about 5-13 pli. The composite has a thickness of less than about 20 mils and a fiberglass content of less than about 25%.
US08741789B2 Flame resistant textile materials providing protection from near infrared radiation
A flame resistant textile material comprises a textile substrate, a flame retardant finish applied to the textile substrate, and an infrared-absorbing finish applied to the textile substrate.
US08741788B2 Formation of silicon oxide using non-carbon flowable CVD processes
A method of forming a silicon oxide layer is described. The method may include the steps of mixing a carbon-free silicon-and-nitrogen containing precursor with a radical precursor, and depositing a silicon-and-nitrogen containing layer on a substrate. The silicon-and-nitrogen containing layer is then converted to the silicon oxide layer.
US08741786B2 Fabrication method of semiconductor device
A disclosed fabrication method of a semiconductor device includes steps of depositing a dielectric film on a semiconductor substrate; thermally treating the dielectric film; and irradiating an ionized gas cluster onto the thermally treated dielectric film.
US08741785B2 Remote plasma radical treatment of silicon oxide
Embodiments described herein generally relate to methods for manufacturing flash memory devices. In one embodiment, the method includes generating a plasma comprising nitrogen-containing radicals in a remote plasma applicator, flowing the plasma comprising nitrogen-containing radicals into a processing region of the processing chamber where a semiconductor device is disposed, wherein the semiconductor device has a substrate comprising an oxide layer formed thereon, exposing an exposed surface of the oxide layer to the nitrogen-containing radicals, and incorporating nitrogen in the exposed surface of the oxide layer of the substrate.
US08741783B2 Cleaning method, method of manufacturing semiconductor device, substrate processing apparatus and recording medium
A method of cleaning an inside of a processing chamber is provided according to an embodiment of the present disclosure. The method includes supplying a fluorine-based gas and a nitrogen oxide-based gas as the cleaning gas, into the processing chamber heated to a first temperature, and removing a deposit by a thermochemical reaction. The method further includes changing a temperature in the processing chamber to a second temperature higher than the first temperature, and supplying the fluorine-based gas and the nitrogen oxide-based gas as the cleaning gas, and removing extraneous materials, remaining on the surface of the member in the processing chamber, by a thermochemical reaction.
US08741781B2 Methods of forming semiconductor constructions
Some embodiments include a semiconductor construction having a pair of lines extending primarily along a first direction, and having a pair of contacts between the lines. The contacts are spaced from one another by a lithographic dimension, and are spaced from the lines by sub-lithographic dimensions. Some embodiments include a method of forming a semiconductor construction. Features are formed over a base. Each feature has a first type sidewall and a second type sidewall. The features are spaced from one another by gaps. Some of the gaps are first type gaps between first type sidewalls, and others of the gaps are second type gaps between second type sidewalls. Masking material is formed to selectively fill the first type gaps relative to the second type gaps. Excess masking material is removed to leave a patterned mask. A pattern is transferred from the patterned mask into the base.
US08741779B2 Plasma processing apparatus and plasma processing method
A plasma processing apparatus for processing an object to be processed using a plasma. The apparatus includes a processing chamber defining a processing cavity for containing an object to be processed and a process gas therein, a microwave radiating antenna having a microwave radiating surface for radiating a microwave in order to excite a plasma in the processing cavity, and a dielectric body provided so as to be opposed to the microwave radiating surface, in which the distance D between the microwave radiating surface and a surface of the dielectric body facing away from the microwave radiating surface, which is represented with the wavelength of the microwave being a distance unit, is determined to be in the range satisfying the inequality 0.7×n/4≦D≦1.3×n/4 (n being a natural number).
US08741778B2 Uniform dry etch in two stages
A method of etching silicon oxide from a multiple trenches is described which allows more homogeneous etch rates among trenches. The surfaces of the etched silicon oxide within the trench following the etch may also be smoother. The method includes two dry etch stages followed by a sublimation step. The first dry etch stage removes silicon oxide quickly and produces large solid residue granules. The second dry etch stage remove silicon oxide slowly and produces small solid residue granules in amongst the large solid residue granules. Both the small and large solid residue are removed in the ensuing sublimation step. There is no sublimation step between the two dry etch stages.
US08741770B2 Semiconductor device and method for patterning vertical contacts and metal lines in a common etch process
Interlayer connections, i.e., vertical connections, may be formed on the basis of a hard mask material, which may be positioned below, within or above an interlayer dielectric material, wherein one lateral dimension is defined by a trench mask, thereby obtaining a desired interlayer connection in a common patterning process. Furthermore, the thickness of at least certain portions of the metal lines may be adjusted with a high degree of flexibility, thereby providing the possibility of significantly reducing the overall resistivity of metal lines in metal levels, in which device performance may significantly depend on resistivity rather than parasitic capacitance.
US08741767B2 Method of forming semiconductor device
A semiconductor device includes a semiconductor substrate including a cell region and a core region adjacent to the cell region, active regions in the cell region and the core region, an interlayer insulating layer covering the active regions, upper cell contacts penetrating the interlayer insulating layer in the cell region, the upper cell contacts being adjacent to each other along a first direction and being electrically connected to the active regions, and core contacts penetrating the interlayer insulating layer in the active regions of the core region, the core contacts being adjacent to each other along the first direction and including upper connection core contacts electrically connected to the active regions, and dummy contacts adjacent to the upper connection core contacts, the dummy contacts being insulated from the active regions.
US08741764B2 Semiconductor device and method of forming conductive pillars having recesses or protrusions to detect interconnect continuity between semiconductor die and substrate
A semiconductor device has a semiconductor die and conductive pillar with a recess or protrusion formed over a surface of the semiconductor die. The conductive pillar is made by forming a patterning layer over the semiconductor die, forming an opening with a recess or protrusion in the patterning layer, depositing conductive material in the opening and recess or protrusion, and removing the patterning layer. A substrate has bump material deposited over a conductive layer formed over a surface of the substrate. The bump material is melted. The semiconductor die is pressed toward the substrate to enable the melted bump material to flow into the recess or over the protrusion if the conductive pillar makes connection to the conductive layer. A presence or absence of the bump material in the recess or protrusion of the conductive pillar is detected by X-ray or visual inspection.
US08741758B2 Cross-hair cell wordline formation
Methods and devices depicting fabrication of non-planar access devices having fins and narrow trenches, among which is a method that includes wet etching a conductor to form a recessed region and subsequently etching the conductor to form gates on the fins. The wet etching may include formation of recesses which are may be backfilled with a fill material to form spacers on the conductor. Portions of a plug may be removed during the wet etch to form overhanging spacers to provide further protection of the conductor during the dry etch.
US08741754B2 Fabricating method of non-volatile memory
A fabricating method of a non-volatile memory is provided. A tunneling dielectric layer and a first conductive layer are sequentially formed on a substrate. Isolation structures are formed in the first conductive layer, the tunneling dielectric layer and the substrate. The first conductive layer is patterned to form protruding portions. A portion of the isolation structures is removed, so that a top surface of each isolation structure is disposed between a top surface of the first conductive layer and a surface of the substrate. An inter-gate dielectric layer is formed on the substrate. A second conductive layer is formed on the inter-gate dielectric layer. The second conductive layer is patterned to form control gates, and the first conductive layer is patterned to form floating gates. The protruding portion of each floating gate is fully covered and surrounded by the control gate in any direction.
US08741748B1 Method to grow group III-nitrides on copper using passivation layers
Group III-nitride epilayers can be grown directly on copper substrates using intermediate passivation layers. For example, single crystalline c-plane GaN can be grown on Cu (110) substrates with MOCVD. The growth relies on a low temperature AlN passivation layer to isolate any alloying reaction between Ga and Cu.
US08741746B2 Silicon on germanium
A monolayer or partial monolayer sequencing processing, such as atomic layer deposition (ALD), can be used to form a semiconductor structure of a silicon film on a germanium substrate. Such structures may be useful in high performance electronic devices. A structure may be formed by deposition of a thin silicon layer on a germanium substrate surface, forming a hafnium oxide dielectric layer, and forming a tantalum nitride electrode. The properties of the dielectric may be varied by replacing the hafnium oxide with another dielectric such as zirconium oxide or titanium oxide.
US08741744B2 Method of forming a gate pattern and a semiconductor device
This disclosure is directed to a method of forming a gate pattern and a semiconductor device. The method comprises: providing a plurality of stacked structures which are parallel to each other and extend continuously in a first direction, and which are composed of a gate material bar and an etching barrier bar thereon; leaving second resist regions between gaps to be formed adjacent to each other across gate bars by a second photolithography process; selectively removing the etching barrier bars by a second etching process; forming a third resist layer having a plurality of openings parallel to each other and extending continuously in a second direction substantially perpendicular to the first direction by a third photolithography process; and forming the gate pattern by a third etching process. The method is capable of having a larger photolithography process window and better controlling the shape and size of a gate pattern.
US08741740B2 Method for manufacturing SOI substrate
An SOI substrate is manufactured by forming an embrittled layer in a bond substrate by increasing the dose of hydrogen ions in the formation of the embrittled layer to a value more than the dose of hydrogen ions of the lower limit for separation of the bond substrate, separating the bond substrate attached to the base substrate, forming an SOI substrate in which a single crystal semiconductor film is formed over the base substrate, and irradiating a surface of the single crystal semiconductor film with laser light.
US08741739B2 High resistivity silicon-on-insulator substrate and method of forming
A semiconductor structure and a method of forming the same. In one embodiment, a method of forming a silicon-on-insulator (SOI) wafer substrate includes: providing a handle substrate; forming a high resistivity material layer over the handle substrate, the high resistivity material layer including one of an amorphous silicon carbide (SiC), a polycrystalline SiC, an amorphous diamond, or a polycrystalline diamond; forming an insulator layer over the high resistivity material layer; and bonding a donor wafer to a top surface of the insulator layer to form the SOI wafer substrate.
US08741736B2 Semiconductor device with improved on-resistance
A semiconductor device includes a source, a drain, and a gate configured to selectively enable a current to pass between the source and the drain. The semiconductor device includes a drift zone between the source and the drain and a first field plate adjacent the drift zone. The semiconductor device includes a dielectric layer electrically isolating the first field plate from the drift zone and charges within the dielectric layer close to an interface of the dielectric layer adjacent the drift zone.
US08741734B2 Semiconductor device and method of fabricating the same
A semiconductor device includes a semiconductor substrate having a trench defining an active region. A wall oxide is formed on side walls of the active region extending in the longitudinal direction, and an element isolation layer is formed in the trenches. A method of manufacturing a semiconductor device includes forming line-shape first trenches on a semiconductor substrate so as to define an active region; forming a wall oxide on surfaces of the first trenches; forming a second trench which separates the active region into a plurality of active regions; and filling the trenches with an element isolation layer.
US08741728B2 Circuit, biasing scheme and fabrication method for diode accessed cross-point resistive memory array
Methods, systems, structures and arrays are disclosed, such as a resistive memory array which includes access devices, for example, back-to-back Zener diodes, that only allow current to pass through a coupled resistive memory cell when a voltage drop applied to the access device is greater than a critical voltage. The array may be biased to reduce standby currents and improve delay times between programming and read operations.
US08741724B2 Method of manufacturing semiconductor device
A semiconductor device includes first, second and isolation regions; a first insulating film and gate electrode formed over the first region; a second insulating film and gate electrode formed over the second region; a first sidewall formed on a side of the first gate electrode and a second sidewall formed on a side of the second gate electrode; first source and drain regions formed adjacent opposite sides of the first gate electrode; second source region adjacent to the one side of the first gate electrode and overlapping the first source region, an impurity concentration of the second source region being different from an impurity of the first source region; a second drain region overlapping the first drain region and overlapping the first gate electrode; and a metal silicide formed on the first source region and the first drain region.
US08741723B2 Methods of forming self-aligned contacts for a semiconductor device
One illustrative method disclosed herein involves forming gate structures for first and second spaced-apart transistors above a semiconducting substrate, forming an etch stop layer above the substrate and the gate structures, performing at least one angled ion implant process to implant at least one etch-inhibiting species into less than an entirety of the etch stop layer, after performing at least one angled ion implant process, forming a layer of insulating material above the etch stop layer, performing at least one first etching process to define an opening in the layer of insulating material and thereby expose a portion of the etch stop layer, performing at least one etching process on the exposed portion of the etch stop layer to define a contact opening therethrough that exposes a doped region formed in the substrate, and forming a conductive contact in the opening that is conductively coupled to the doped region.
US08741719B1 Integrating formation of a logic transistor and a non-volatile memory cell using a partial replacement gate technique
A thermally-grown oxygen-containing gate dielectric and select gate are formed in an NVM region. A high-k gate dielectric, barrier layer, and dummy gate are formed in a logic region. The barrier layer may include a work-function-setting material. A first dielectric layer is formed in the NVM and logic regions which surrounds the select gate and dummy gate. The first dielectric layer is removed from the NVM region and protected in the logic region. A charge storage layer is formed over the select gate. The dummy gate is removed, resulting in an opening. A gate layer is formed over the charge storage layer in the NVM region and within the opening in the logic region, wherein the gate layer within the opening together with the barrier layer form a logic gate in the logic region, and the gate layer is patterned to form a control gate in the NVM region.
US08741716B2 Semiconductor device with a gate having a bulbous area and a flattened area underneath the bulbous area and method for manufacturing the same
A semiconductor device with a gate having a bulbous area and a flattened area underneath the bulbous area is presented. The semiconductor device includes a semiconductor substrate, an isolation layer, a gate insulation layer, and gates. The semiconductor substrate has recess parts that have first grooves which have bulbous-shaped profiles and second vertically flattened profile grooves which extend downward from the first grooves. The gates are formed in the recess parts in which the gate insulation layer is double layered in the bulbous profile areas and is single layered in the flattened profile areas.
US08741715B2 Gate electrodes for millimeter-wave operation and methods of fabrication
A transistor device having a tiered gate electrode fabricated with methods using a triple layer resist structure. The triple layer resist stack is deposited on a semiconductor structure. An exposure pattern is written onto the resist stack using an e-beam writer, for example. The exposure dose is non-uniform across the device. Portions of the three resist layers are removed with a sequential development process, resulting in tiered resist structure. A conductive material is deposited to form the gate electrode. The resulting “Air-T” gate also has a three-tiered structure. The fabrication process is well-suited for the production of gates small enough for use in millimeter wave devices.
US08741714B2 Support lines to prevent line collapse in arrays
Methods for preventing line collapse during the fabrication of NAND flash memory and other microelectronic devices that utilize closely spaced device structures with high aspect ratios are described. In some embodiments, one or more mechanical support structures may be provided to prevent the collapse of closely spaced device structures during fabrication. In one example, during fabrication of a NAND flash memory, one or more mechanical support structures may be set in place prior to performing a high aspect ratio word line etch for forming the NAND strings. The one or more mechanical support structures may comprise one or more fin supports that are arranged in a bit line direction. In another example, the one or more mechanical support structures may be developed during the word line etch for forming the NAND strings.
US08741709B2 Vertical power MOSFET and IGBT fabrication process with two fewer photomasks
A process for fabrication of a power semiconductor device is disclosed in which a single photomask is used to define each of p-conductivity well regions and n-conductivity type source regions. In the process a single photomask is deposited on a layer of polysilicon on a wafer, the polysilicon layer is removed from first regions of the power semiconductor device where the p-conductivity well regions and the n-conductivity type source regions are to be formed, and both p-conductivity type and n-conductivity type dopants are introduced into the wafer through the first regions.
US08741708B2 Transistor and method for forming the same
A transistor and a method for forming the transistor are provided. The transistor can be formed over a substrate including a first region and second regions on opposite sides of the first region. On the substrate, a first SiGe layer can be formed, followed by forming a first silicon layer on the first SiGe layer and forming a second SiGe layer on the first silicon layer. The second SiGe layer and the first silicon layer within the second regions are removed. The first silicon layer within the first region is removed to form a cavity such that the second SiGe layer is floated. An isolating layer is formed in the cavity. Second silicon layers are formed in the second regions. A gate structure is formed on the second SiGe layer within the first region and the second silicon layers are doped to form a source and a drain.
US08741705B2 Metal-oxide-semiconductor high electron mobility transistors and methods of fabrication
A method of fabricating Group III-V semiconductor metal oxide semiconductor (MOS) and III-V MOS devices are described.
US08741696B2 Methods of forming pillars for memory cells using sequential sidewall patterning
The present invention provides apparatus, methods, and systems for fabricating memory structures methods of forming pillars for memory cells using sequential sidewall patterning. The invention includes forming first features from a first template layer disposed above a memory layer stack; forming first sidewall spacers adjacent the first features; forming second features that extend in a first direction in a mask layer by using the first sidewall spacers as a hardmask; depositing a second template layer on the mask layer; forming third features from the second template layer; forming second sidewall spacers adjacent the third features; and forming fourth features that extend in a second direction in the mask layer by using the second sidewall spacers as a hardmask. Numerous additional aspects are disclosed.
US08741693B2 Method for manufacturing package structure with micro-electromechanical element
A package structure includes a micro-electromechanical element having a plurality of electrical contacts; a package layer enclosing the micro-electromechanical element and the electrical contacts, with a bottom surface of the micro-electromechanical element exposed from a lower surface of the package layer; a plurality of bonding wires embedded in the package layer, each of the bonding wires having one end connected to one of the electrical contacts, and the other end exposed from the lower surface of the package layer; and a build-up layer structure provided on the lower surface of the package layer, the build-up layer including at least one dielectric layer and a plurality of conductive blind vias formed in the dielectric layer and electrically connected to one ends of the bonding wires. The package structure is easier to accurately control the location of an external electrical contact, and the compatibility of the manufacturing procedures is high.
US08741690B2 Packaged semiconductor device with encapsulant embedding semiconductor chip that includes contact pads
A method of manufacturing a semiconductor package includes embedding a semiconductor chip in an encapsulant. First contact pads are formed on a first main face of the semiconductor package and second contact pads are formed on a second main face of the semiconductor package opposite the first main face. A diameter d in micrometers of an exposed contact pad area of the second contact pads satisfies d≧(8/25)x+142 μm, where x is a pitch of the second contact pads in micrometers.
US08741689B2 Thermal pre-treatment process for soda lime glass substrate for thin film photovoltaic materials
A method for fabricating a thin film solar cell includes providing a soda lime glass substrate comprising a surface region, treating the surface region with one or more cleaning process including an aqueous solution to remove one or more contaminants and/or particulates, and forming a lower electrode layer overlying the surface region. The method also includes performing a thermal treatment process to remove any residual water species to substantially less than a monolayer of water species from the lower electrode layer and soda lime glass substrate. The thermal treatment process changes a temperature of the soda lime glass substrate from a first temperature to a second temperature to pre-heat the soda lime glass substrate. Additionally, the method includes transferring the soda lime glass substrate, which has been preheated, to a deposition chamber and forming a layer of photovoltaic material overlying the lower electrode layer within the deposition chamber.
US08741688B2 Methods of forming a metal chalcogenide material
Accordingly, a method of forming a metal chalcogenide material may comprise introducing at least one metal precursor and at least one chalcogen precursor into a chamber comprising a substrate, the at least one metal precursor comprising an amine or imine compound of an alkali metal, an alkaline earth metal, a transition metal, a post-transition metal, or a metalloid, and the at least one chalcogen precursor comprising a hydride, alkyl, or aryl compound of sulfur, selenium, or tellurium. The at least one metal precursor and the at least one chalcogen precursor may be reacted to form a metal chalcogenide material over the substrate. A method of forming a metal telluride material, a method of forming a semiconductor device structure, and a semiconductor device structure are also described.
US08741685B2 Sulfurization and selenization of electrodeposited CIGS films by thermal annealing
The invention relates to a method for production of thin layers of semiconductor alloys of the I-III-VI2 type, including sulphur, for photovoltaic applications, whereby a heterostructure is firstly deposited on a substrate comprising a thin layer of precursor I-III-VI2 which is essentially amorphous and a thin layer, including at least some sulphur, the heterostructure is then annealed to promote the diffusion of the sulphur into the precursor layer and the at least partial crystallization of the I-III-VI2 alloy of the precursor layer with a stoichiometry which hence includes sulphur. A layer of selenium may also be deposited to assist the recrystallization processes or annealing.
US08741684B2 Co-integration of photonic devices on a silicon photonics platform
Disclosed are methods for co-integration of active and passive photonic devices on a planarized silicon-based photonics substrate. In one aspect, a method is disclosed that includes providing a planarized silicon-based photonics substrate comprising a silicon waveguide structure, depositing a dielectric layer over the planarized silicon-based photonics substrate, selectively etching the dielectric layer, thereby exposing at least a portion of the silicon waveguide structure, selectively etching the exposed portion of the silicon waveguide structure to form a template, using the silicon waveguide structure as a seed layer to selectively grow in the template a germanium layer that extends above the dielectric layer, and planarizing the germanium layer to form a planarized germanium layer, wherein the planarized germanium layer does not extend above the dielectric layer.
US08741679B2 Surface treatment method by using the NH3 plasma treatment to modify the sensing thin-film
The NH3 plasma treatment by remote plasma is firstly proposed to replace the covalent bonding process during surface modification procedure that for amine bond generation.
US08741678B2 Transparent conductive electrode stack containing carbon-containing material
A transparent conductive electrode stack containing a work function adjusted carbon-containing material is provided. Specifically, the transparent conductive electrode stack includes a layer of a carbon-containing material and a layer of a work function modifying material. The presence of the work function modifying material in the transparent conductive electrode stack shifts the work function of the layer of carbon-containing material to a higher value for better hole injection into the OLED device as compared to a transparent conductive electrode that includes only a layer of carbon-containing material and no work function modifying material.
US08741677B2 Display device and manufacturing method of the same
A display device free of contact resistance between a drain electrode (or a source electrode) and a pixel electrode. The display device includes a gate electrode, a gate insulating layer covering the gate electrode, a semiconductor layer formed over the gate insulating layer, and a source electrode and a drain electrode separated from each other and in partial-contact with and over the semiconductor layer, and one of the source electrode and the drain electrode also serves as a pixel electrode, the other of the source electrode and the drain electrode also serves as a signal line, and a low resistant conductive layer is preferably formed over the other of the source electrode and the drain electrode. The low resistant conductive layer can be formed by an electroplating method or the like.
US08741676B2 Method of manufacturing OLED-on-silicon
A method of manufacturing an Organic Light Emitting Diode (OLED). A substrate (101) is provided, and a plurality of pixel electrodes (102) is formed on the substrate resulting in at least one gap (105) between two adjacent pixel electrodes. A dielectric material (103) is deposited in the gap. The resulting structure is subjected to a process which ensures that at least a portion of the surface of the pixel electrodes is not covered by the dielectric material. At least the portion of the surface of the pixel electrodes is covered with a layer of an organic compound so as to form the OLED.
US08741675B2 Method of manufacturing semiconductor light emitting device and mask for application of paste used therefor
Provided are a mask for an application of paste and a method of manufacturing a semiconductor light emitting device by using the same. The method includes preparing a light emitting structure including first and second conductive semiconductor layers and an active layer disposed therebetween, which has at least one electrode formed on a surface of the light emitting structure; disposing a mask having an open part exposing a portion of the surface of the light emitting structure therethrough and a recess part corresponding the electrode in a region thereof on a surface of the light emitting structure; and applying wavelength conversion material-containing paste to the surface of the light emitting structure through the open part.
US08741674B2 Group-III nitride semiconductor laser device, and method for fabricating group-III nitride semiconductor laser device
Provided is a group-III nitride semiconductor laser device with a laser cavity of high lasing yield, on a semipolar surface of a support base in which the c-axis of a hexagonal group-III nitride is tilted toward the m-axis. First and second fractured faces to form the laser cavity intersect with an m-n plane. The group-III nitride semiconductor laser device has a laser waveguide extending in a direction of an intersecting line between the m-n plane and the semipolar surface. In a laser structure, a first surface is opposite to a second surface. The first and second fractured faces extend from an edge of the first surface to an edge of the second surface. The fractured faces are not formed by dry etching and are different from conventionally-employed cleaved facets such as c-planes, m-planes, or a-planes.
US08741673B2 Polarized light emitting diode device and method for manufacturing the same
The present invention relates to a polarized light emitting diode (LED) device and the method for manufacturing the same, in which the LED device comprises: a base, a light emitting diode (LED) chip, a polarizing waveguide and a packaging material. In an exemplary embodiment, the LED chip is disposed on the base and is configured with a first light-emitting surface for outputting light therefrom; and the waveguide, being comprised of a polarization layer, a reflection layer, a conversion layer and a light transmitting layer, is disposed at the optical path of the light emitted from the LED chip; and the packaging material is used for packaging the waveguide, the LED chip and the base into a package.
US08741671B2 Method for manufacturing light emitting device having an active layer formed over a Ga-face
A method for manufacturing a light emitting device is disclosed. The disclosed method includes forming a first-conductivity-type semiconductor layer over a first substrate such that a first surface of the first-conductivity-type semiconductor layer is adjacent to the first substrate, disposing a second substrate on a second surface of the first-conductivity-type semiconductor layer opposite the first surface, separating the first substrate, disposing a third substrate on the first surface, separating the second substrate, and forming an active layer and a second-conductivity-type semiconductor layer over the second surface. In accordance with the method, it is possible to use a relatively inexpensive substrate. As a semiconductor layer is formed over a Ga-face of a gallium nitride semiconductor layer, an increase in light emission efficiency is achieved.
US08741670B2 Method for producing integrated optical device
A method for producing an integrated optical device includes the steps of growing a first stacked semiconductor layer including a first optical waveguiding layer, a first cladding layer, and a side-etching layer; etching the first stacked semiconductor layer through a first etching mask; growing, a second stacked semiconductor layer including a second optical waveguiding layer and a second cladding layer through the first etching mask; and forming a reverse-mesa ridge structure by etching the first and second cladding layers. The step of etching the first stacked semiconductor layer includes a step of forming an overhang by etching the side-etching layer by wet etching. In the step of growing the second stacked semiconductor layer, the second cladding layer is grown at a lower growth temperature and a higher V/III ratio comparing to those in the growth of the second optical waveguiding layer.
US08741668B1 Thin overlay mark for imaging based metrology
A thin overlay structure for use in imaging based metrology is disclosed. The thin overlay structure may include a first structure and second structure, the first and second structures designed to have a common center of symmetry, both structures being invariant to a 180 degree rotation about the common center of symmetry, wherein a mark region defining the extent of the structures is characterized by a first direction and a second direction orthogonal to the first direction, a length of the mark region along the first direction being greater than a length of the mark region along the second direction.
US08741666B1 Methods relating to intermetallic testing of bond integrity between bond pads and copper-containing bond wires
Methods relating to intermetallic compound testing of copper-based wire bonds are provided. For example, a method is generally provided for testing the integrity of wire bonds formed between copper-containing wires and the bond pads of a plurality of microelectronic devices. In one embodiment, the method includes selecting at least one wire bond sample produced in conjunction with the wire bonds formed between the copper-containing wires and the bond pads of the microelectronic devices. One or more copper-containing wires of the wire bond sample are contacted with a liquid copper etchant, which contains a sulfate-based oxidizing agent dissolved in a solvent, to cause separation of the copper-containing wires from the bond pads and exposure of the underlying wire-pad interfaces. Intermetallic compounds formed at the exposed wire-pad interfaces are then measured to assess the integrity of the wire bonds.
US08741664B2 Magnetic tunnel junction self-alignment in magnetic domain wall shift register memory devices
A method of fabricating a self-aligning magnetic tunnel junction the method includes patterning a lithographic strip on a second magnetic material deposited on a first magnetic material that is disposed on a substrate, forming a top magnetic strip by etching an exposed portion of the second magnetic material, patterning a nanowire and a magnetic reference layer island over the substrate and forming the nanowire and the magnetic reference layer island by etching an exposed portion of the first magnetic layer and an exposed portion of the top magnetic strip, wherein an interface between the magnetic nanowire and the magnetic reference layer island is an magnetic tunnel junction aligned with a width of the nanowire.
US08741660B2 Sampling device
The present invention generally relates to devices, systems, and methods for acquiring and/or dispensing a sample without introducing a gas into a microfluidic system, such as a liquid bridge system. An exemplary embodiment provides a sampling device including an outer sheath; a plurality of tubes within the sheath, in which at least one of the tubes acquires a sample, and at least one of the tubes expels a fluid that is immiscible with the sample, in which the at least one tube that acquires the sample is extendable beyond a distal end of the sheath and retractable to within the sheath; and a valve connected to a distal portion of the sheath, in which the valve opens when the tube extends beyond the distal end and closes when the tube retracts to within the sheath.
US08741657B1 Nanocomposite thin films for optical gas sensing
The disclosure relates to a plasmon resonance-based method for gas sensing in a gas stream utilizing a gas sensing material. In an embodiment the gas stream has a temperature greater than about 500° C. The gas sensing material is comprised of gold nanoparticles having an average nanoparticle diameter of less than about 100 nanometers dispersed in an inert matrix having a bandgap greater than or equal to 5 eV, and an oxygen ion conductivity less than approximately 10−7 S/cm at a temperature of 700° C. Exemplary inert matrix materials include SiO2, Al2O3, and Si3N4 as well as modifications to modify the effective refractive indices through combinations and/or doping of such materials. Changes in the chemical composition of the gas stream are detected by changes in the plasmon resonance peak. The method disclosed offers significant advantage over active and reducible matrix materials typically utilized, such as yttria-stabilized zirconia (YSZ) or TiO2.
US08741655B2 Transport system for test sample carrier
A transport system is provided for a sample testing machine. The transport system includes a carrier holding a set of test sample devices and a drive subsystem for moving the carrier through the sample testing machine. The drive subsystem includes a reciprocating motor-driven block engaging the carrier and moving the carrier back and forth in a predetermined longitudinal path extending along a longitudinal axis from an entrance station to a plurality of processing stations in the sample testing machine. The processing stations are accessed as the carrier is moved along the path. The carrier includes features in the form of slots or voids that are detected by strategically placed optical interrupt sensors. As the carrier moves, the slots are detected by the sensors to thereby continuously track the position of the carrier and the test devices as they are moved through the instrument.
US08741652B2 Genetically transformed microorganisms with simultaneous enhancement of reduction potential and reductive enzyme activities for biomass fermentation
The present invention describes the genetic engineering of production microorganisms used in biotechnology to improve their properties so that they produce industrially useful products more efficiently from fermentable sugars derived from biomass. The engineered microorganisms endowed with functional coupling of oxidation and reduction of substrates by dehydrogenases requiring pyridine nucleotides (NAD/NADH) result in simultaneous enhancement of reduction potential enzyme activity involving the transfer of electrons. In particular, this invention relates to the construction of an excisable gene expression cassette for expression of two different dehydrogenases leading to enhanced production of ethanol.
US08741648B2 Reprogramming T cells and hematopoietic cells
Methods and compositions relating to the production of induced pluripotent stem cells (iPS cells) are disclosed. For example, induced pluripotent stem cells may be generated from CD34+ hematopoietic cells, such as human CD34+ blood progenitor cells, or T cells. Various iPS cell lines are also provided. In certain embodiments, the invention provides novel induced pluripotent stem cells with a genome comprising genetic rearrangement of T cell receptors.
US08741641B2 Methods for evaluating the stage of ovarian cancer or the survival rate of an ovarian cancer patient
An object of the present invention is to provide a method for detecting cancer through identification of genes exhibiting characteristic behavior in the cases of cancer such as ovarian cancer, and a cell growth inhibitor. The present invention provides a method for detecting cancer, which comprises detecting canceration including malignancy of a specimen through detection of at least one alteration of a gene existing in a chromosomal region 2q14. 2, 3p24. 1, 3q26. 2, 3q29, 4q34. 2, 6q23, 9p21. 3, 11q13. 3, 13q22.1, 13q33. 1, 13q33. 3, 15q12, 15q15. 1, 17p12, 17p13. 1, 17p13. 3, 18q21. 1, 18q21. 2, 18q21. 31, 18q21. 32, 18q21. 33, 18q23, 20q13. 13, 20q13. 2, 20q13. 31, 20q13. 33, Xp11. 23, Xp13.1, Xp13. 3, Xp26. 2, Xp26. 3, or Xq28 in the specimen.
US08741638B2 In vitro expansion of postpartum-derived cells in roller bottles
Methods for the maximizing parameter of the in vitro growth and expansion of mammalian cells, specifically postpartum-derived cells in containers such as roller bottles is described. Methods of optimizing growth rate and cell yield in such culture systems are provided. The methods are particularly adapted for human postpartum-derived cells, such as umbilicus-derived cells.
US08741635B2 Method of cell isolation
The present invention relates generally to a method for the generation of a substantially homogenous population of undifferentiated cells. More particularly, the present invention relates to a method for isolating a substantially homogenous population of stem cells, and in particular, mammary stem cells (MaSCs). The MaSCs of the present invention are isolated on the basis of differential levels of proteins present on their cell surface. The MaSCs of the present invention are particularly useful as targets for identifying agents which modulate MaSC survival, self-renewal, proliferation and/or differentiation in both normal and diseased tissue such as, but not limited to, tumor tissue, and, also as source of tissue for the regeneration, replacement and/or augmentation of tissue damaged and/or lost after disease or injury.
US08741633B2 Recombinant vectors
Methods and materials are provided for integrating heterologous nucleic acids into the genome of a cell or virus without disrupting expression of genes adjacent to the insertion site.
US08741625B2 Microorganism and deodorizer containing the same
Thermophilic microorganisms having a deodorizing ability for short chain fatty acids, which are the offensive odor components, are provided. Disclosed are thermophilic microorganisms having a deodorizing ability for short chain fatty acids, which belong to Bacillus licheniformis.
US08741623B2 Process for the production of cadaverine
Process for the production of cadaverine by constructing a recombinant microorganism which has a deregulated lysine decarboxylase gene and at least one deregulated gene selected from the group (i) which consists of aspartokinase, aspartatesemialdehyde dehydrogenase, dihydrodipicolinate synthase, dihydrodipicolinate reductase, tetrahydrodipicolinate succinylase, succinyl-amino-ketopimelate transaminase, succinyl-diamino-pimelate desuccinylase, diaminopimelate epimerase, diaminopimelate dehydrogenase, arginyl-tRNA synthetase, diaminopimelate decarboxylase, pyruvate carboxylase, phosphoenolpyruvate carboxylase, glucose-6-phosphate dehydrogenase, transketolase, transaldolase, 6-phosphogluconolactonase, fructose 1,6-biphosphatase, homoserine dehydrogenase, phophoenolpyruvate carboxykinase, succinyl-CoA synthetase, methylmalonyl-CoA mutase, provided that if aspartokinase is deregulated as gene (i) at least a second gene (i) other than aspartokinase has to be deregulated, and cultivating said microorganism.
US08741620B2 Human lysosomal proteins from plant cell culture
A device, system and method for producing glycosylated proteins in plant culture, particularly proteins having a high mannose glycosylation, while targeting such proteins with an ER signal and/or by-passing the Golgi. The invention further relates to vectors and methods for expression and production of enzymatically active high mannose lysosomal enzymes using transgenic plant root, particularly carrot cells. More particularly, the invention relates to host cells, particularly transgenic suspended carrot cells, vectors and methods for high yield expression and production of biologically active high mannose Glucocerebrosidase (GCD). The invention further provides for compositions and methods for the treatment of lysosomal storage diseases.
US08741617B2 DNA polymerases with increased 3′-mismatch discrimination
Disclosed are mutant DNA polymerases having increased 3′-mismatch discrimination relative to a corresponding, unmodified polymerase. The mutant polymerases are useful in a variety of disclosed primer extension methods. Also disclosed are related compositions, including recombinant nucleic acids, vectors, and host cells, which are useful, e.g., for production of the mutant DNA polymerases.
US08741616B2 Regio- and enantioselective alkane hydroxylation with modified cytochrome P450
Cytochrome P450 BM-3 from Bacillus megaterium was engineered using a combination of directed evolution and site-directed mutagenesis to hydroxylate linear alkanes regio- and enantioselectively using atmospheric dioxygen as an oxidant. Mutant 9-10A-A328V hydroxylates octane primarily at the 2-positio to form S-2-octanol (40% ee). Another mutant, 1-12G, hydroxylates alkanes larger than hexane primarily at the 2-position, but forms R-2-alcohols (40-55% ee). These biocatalysts are highly active for alkane substrates and support thousands of product turnovers. These regio- and enantio-selectivities are retained in whole-cell biotransformations with E. coli, where the engineered P450s can be expressed at high levels and the expensive cofactor is supplied endogenously.
US08741612B2 Microorganisms and processes for the production of isoprene
The present invention provides a novel biosynthetic pathway for the production of isoprene from 3-methyl-2-buten-1-ol or 2-methyl-3-buten-2-ol. Further embodiments provide non-naturally occurring microorganism that have been modified to produce isoprene from 3-methyl-2-buten-1-ol or 2-methyl-3-buten-2-ol and methods of producing isoprene using said microorganism.
US08741611B2 Methods for improving malic acid production in filamentous fungi
The present invention relates to methods of producing a C4 dicarboxylic acid, comprising: (a) cultivating a filamentous fungal host cell comprising a polynucleotide selected from the group consisting of a heterologous first polynucleotide encoding a C4 dicarboxylic acid transporter, a heterologous second polynucleotide encoding a malate dehydrogenase, and a heterologous third polynucleotide encoding a pyruvate carboxylase; wherein the filamentous fungal host cell is capable of secreting increased levels of the C4 dicarboxylic acid compared to the filamentous fungal host cell without the heterologous polynucleotide when cultivated under the same conditions; and (b) recovering the C4 dicarboxylic acid. The present invention also relates to methods for increasing C4 dicarboxylic acid production, filamentous fungal host cells and malate dehydrogenase variants.
US08741601B2 Method for producing a cell capable of high-yield production of heteroproteins
The present invention provides a cell capable of high-yield production of polypeptides and a method for producing the same.The present invention relates to a method for producing a cell capable of high-yield production of a desired polypeptide, wherein a strongly bicarbonate transporter-expressing cell into which DNA encoding the desired polypeptide has been introduced is cultured in the presence of a high concentration of methotrexate and a cell capable of high-yield production of the desired polypeptide is selected from among surviving cells.
US08741596B2 Smart packaging for detecting microorganisms
The present invention relates to novel smart packaging, designed using a novel material comprising a partially polar adsorbent solid base impregnated with a solution of vanillin, which allows the growth of microorganisms in different types of products to be detected visually without having to be in direct contact with the microorganism or with the medium containing same.
US08741594B2 Mitochondrial enoyl coenzyme A hydratase 1 as marker for diagnosing stomach cancer
The present invention relates to mitochondrial protein that can be used as a marker for diagnosing stomach cancer. According to the present invention, the marker for diagnosing stomach cancer comprises mitochondrial enoyl coenzyme A hydratase 1.
US08741590B2 Subcutaneous glucose electrode
A small diameter flexible electrode designed for subcutaneous in vivo amperometric monitoring of glucose is described. The electrode is designed to allow “one-point” in vivo calibration, i.e., to have zero output current at zero glucose concentration, even in the presence of other electroreactive species of serum or blood. The electrode is preferably three or four-layered, with the layers serially deposited within a recess upon the tip of a polyamide insulated gold wire. A first glucose concentration-to-current transducing layer is overcoated with an electrically insulating and glucose flux limiting layer (second layer) on which, optionally, an immobilized interference-eliminating horseradish peroxidase based film is deposited (third layer). An outer (fourth) layer is biocompatible.
US08741589B2 Monitoring two dimensions of diabetes pathogenesis
Provided are methods for determining concurrently with a simple, minimally invasive test, the adequacy of pancreatic beta-cell compensation and/or the presence of tissue insulin resistance in a subject human or an experimental animal. The methods allow for the determination of a subject's or experimental animal's susceptibility to developing type 2 diabetes mellitus (DM2) or to progression to more advanced forms of DM2. Among other uses, the methods allow for diagnostic classification of subjects for decisions regarding therapeutic interventions, clinical differentiation between type 1 DM and DM2, clinical monitoring of treatments intended to reduce risk of developing DM2 in non-diabetic subjects, clinical monitoring of agents intended to improve existing DM2 and to prevent progression of DM2, clinical development and testing of new compounds, candidate agents, or candidate therapies for preventing progression to DM2 or disease progression in existing DM2, and preclinical screening of candidate agents or candidate therapies in experimental animals to identify and characterize agents having insulin-sensitizing properties, pancreatic stimulatory or regenerative properties or other desirable actions.
US08741587B2 ARMET as a marker for cancer
Disclosed is a method aiding in the assessment of cancer. More specifically disclosed is the use of the arginine-rich metastasized in early tumors protein (=ARMET) as a universal marker of different cancer types. ARMET aids in the assessment of pulmonary or lung cancer (LC) or of colon cancer, e.g., of non-small cell lung carcinoma (NSCLC) or colorectal cancer (CRC), but also likely of other specific types of cancer. Such specific cancer types are, e.g., breast, ovary, cervix, head and neck, endometrium, melanoma, bladder, kidney, pancreas, prostate, esophagus, stomach or bile duct cancer. Further disclosed is a method for assessing cancer from a liquid sample, derived from an individual by measuring ARMET in the sample. Measurement of ARMET can, e.g., be used in the early detection of cancer or in the surveillance of patients who undergo surgery.
US08741586B2 Antibodies against HER2 truncated variant CTF-611
The present invention relates to a method of diagnosis and therapy of cancers expressing the HER2 receptor.The invention provides antibodies or fragments thereof that recognise an epitope of the HER2 receptor truncated form CTF-611, said epitope being defined by a sequence included in SEQ ID NO: 2, and that are capable of discriminating between CTF-611 and CTF-616 (represented by SEQ ID NO:7), preferably additionally capable of discriminating between CTF-611 and CTF-613 (represented by SEQ ID NO:6).The invention also provides a method of cancer diagnosis using the disclosed antibodies, which comprises the detection of the presence of the HER2 receptor truncated form consisting of the amino acid sequence SEQ ID NO: 1 in a patient sample.
US08741585B2 Electronic methods for the detection of analytes
The present invention is directed to the detection of target analytes using electronic techniques, particularly AC techniques.
US08741584B2 Follistatin-like protein-1 as a biomarker for inflammatory disorders
The present invention relates to methods and compositions for diagnosis of inflammatory disorders, and in non-limiting embodiments, of inflammatory disorders associated with elevated interleukin-1β (“IL-1β”), based on increased levels of follistatin-like protein 1 (“FSTL-1”). In particular non-limiting embodiments, the invention further provides for methods of identifying subjects with systemic onset juvenile idiopathic arthritis (“SOJIA”) who are at increased risk for developing macrophage activation syndrome (“MAS”) comprising detecting, in said subjects, hyper-increased levels of FSTL-1. In additional non-limiting embodiments, the invention provides for methods of identifying subjects with Kawasaki disease who are at increased risk of developing aortic aneurysms comprising detecting, in said subjects, hyper-increased levels of FSTL-1.
US08741583B2 Method of identifying compounds that inhibit fertilization
A method of identifying compounds that inhibit fertilization is provided. The method can include selecting compounds that bind to equatorin protein. Two types of equatorin protein, a long form and a short form, can be present in the testis. The amino acid sequence of mouse equatorin from positions 101 to 146 including the 138th O-glycosylated threonine residue contains an epitope recognized by anti-equatorin antibody MN9 that has an effect of inhibiting fertilization. In addition, the MN9 antibody also binds to human sperm. Compounds that bind to the epitope can inhibit fertilization. Both forms of mouse equatorin can be used as well as human equatorin to identify compounds that inhibit fertilization.
US08741582B2 Detection of a specific DEK isoform as a urine-based biomarker for bladder cancer
The present invention is directed to a method of detecting a DEK protein isoform 2 in a human urine sample using ELISA. Methods and compositions for detection of DEK isoform 2 in human urine are provided herein. The presence of DEK isoform 2 in urine is shown to correlate with bladder cancer in humans.
US08741581B2 Markers for cancer detection
The present invention relates to methods for detecting, prognosing and staging cancers, in particular cancers of the gastrointestinal tract. The methods of the invention comprise detecting specific protein markers in a tissue of interest, wherein the detected levels thereof may be indicative of pre-cancerous or cancerous tissue, or the stage or prognosis of a cancer. Further provided are methods of treating cancer, and cancer detection kits.
US08741578B2 Methods of detecting chronic lymphocytic leukemia with Hsp90 and ZAP-70
Provided are compositions and methods useful for treating and diagnosing cell proliferative disorders associated with Hsp90 and/or ZAP-70.
US08741572B1 Methods of screening for compounds for treating muscular dystrophy using mIGF1 mRNA translation regulation
The present invention provides compounds and assays for the identification and validation of compounds for use in the treatment of muscular mystrophy (MD), or a form thereof, in which said compounds increase the post-transcriptional expression of a target gene (i.e., mIGF1, ITGA7, or UTRN).
US08741571B2 Using populations of beads for the fabrication of arrays on surfaces
The present invention provides a method of creating an array of features. The method can include steps of (a) providing a plurality of beads, wherein each bead in the plurality of beads includes probe content; (b) contacting the plurality of beads with a surface to produce a layer of beads on the surface; and (c) transferring the probe content from the beads to the surface to create an array of spatially discrete features on the surface, wherein each spatially discrete feature includes probe content from a bead in the plurality of beads.
US08741568B2 Detection of human papillomavirus
There is provided an in vitro method of detecting human papillomavirus nucleic acid in a sample, comprising: (a) contacting said sample with forward and reverse oligonucleotide primers, wherein said primers bind to target sites in the human papillomavirus L1 gene, or the complement thereof, under conditions suitable to promote amplification of a portion of said human papillomavirus L1 gene or complement, thereby generating an amplicon; (b) contacting said amplicon with a probe, wherein the probe binds to a target site within said amplicon; and (c) detecting binding of said probe to said amplicon; wherein said forward primer binds to a target site having the sequence SEQ ID NO: 1; and wherein said reverse primer binds to a target site having the sequence SEQ ID NO: 2.
US08741566B2 Immunohistochemistry and in situ hybridization detection method
The invention provides compositions and methods for the detection of targets in a sample; in particular, an immunohistochemistry (IHC) sample. Probes and detectable labels may be provided in multiple layers in order to increase the flexibility of a detection system, and to allow for amplification to enhance the signal from a target. The layers may be created by incorporating probes and detectable labels into larger molecular units that interact through nucleic acids base-pairing, including peptide-nucleic acid (PNA) base-pairing. Optional non-natural bases allow for degenerate base pairing schemes. The compositions and methods are compatible with immunohistochemistry (IHC), but also could be used in immunocytochemistry (ICC), in situ hybrid.
US08741561B2 Gene sets for detection of ultraviolet A exposure and methods of use thereof
Ultraviolet radiation (UVR) has profound effects on human skin. However, its effects on the global transcriptome in vivo have not been well characterized. In addition, the contribution of the UVA component of UVR has not been previously assessed in vivo. Disclosed herein is the identification of sets of genes that are either up-regulated or down-regulated in response to UVA exposure. The gene sets described herein can be used to accurately identify skin samples that have been exposed to UVA and to assess the ability of a sun protection product to block the effects of UVA.
US08741554B2 Patterning process and resist composition
A pattern is formed by coating a first positive resist composition comprising a base resin, a photoacid generator, and a base generator onto a substrate to form a first resist film, patternwise exposure, PEB, and development to form a first resist pattern, heating the first resist pattern for causing the base generator to generate a base for inactivating the pattern to acid, coating a second positive resist composition comprising a C3-C8 alcohol and an optional C6-C12 ether onto the first resist pattern-bearing substrate to form a second resist film, patternwise exposure, PEB, and development to form a second resist pattern.
US08741551B2 Method and composition of a dual sensitive resist
The present disclosure provides a sensitive material. The sensitive material includes a polymer that turns soluble to a base solution in response to reaction with acid; a plurality of photo-base generators (PBGs) that decompose to form base in response to radiation energy; and a thermal sensitive component that generates acid in response to thermal energy.
US08741548B2 Patterning process
A pattern is formed by applying a first positive resist composition onto a substrate, heat treatment, exposure, heat treatment and development to form a first resist pattern; causing the first resist pattern to crosslink and cure by irradiation of high-energy radiation of up to 180 nm wavelength or EB; further applying a second positive resist composition onto the substrate, heat treatment, exposure, heat treatment and development to form a second resist pattern. The double patterning process reduces the pitch between patterns to one half.
US08741546B2 Patterning process and resist composition
A pattern is formed by coating a first positive resist composition comprising a copolymer comprising lactone-containing recurring units, acid labile group-containing recurring units and carbamate-containing recurring units, and a photoacid generator onto a substrate to form a first resist film, patternwise exposure, PEB, and development to form a first resist pattern, heating the first resist pattern for inactivation to acid, coating a second positive resist composition comprising a C3-C8 alcohol and an optional C6-C12 ether onto the first resist pattern-bearing substrate to form a second resist film, patternwise exposure, PEB, and development to form a second resist pattern.
US08741545B2 Fluorine-free fused ring heteroaromatic photoacid generators and resist compositions containing the same
The present invention relates to a fluorine-free photoacid generator (PAG) and a photoresist composition containing the same. The PAG is characterized by the presence of an onium cationic component and a fluorine-free fused ring heteroaromatic sulfonate anionic component containing one or more electron withdrawing substituents. The onium cationic component of the PAG is preferably a sulfonium or an iodonium cation. The photoresist composition further contains an acid sensitive imaging polymer. The photoresist composition is especially useful for forming material patterns on a semiconductor substrate using 193 nm (ArF) lithography.
US08741543B2 Resist composition and method for producing resist pattern
A resist composition having a resin having a structural unit represented by the formula (I), a resin being insoluble or poorly soluble in alkali aqueous solution, but becoming soluble in an alkali aqueous solution by the action of an acid and not including the structural unit represented by the formula (I), and an acid generator having an acid labile group, wherein R1, A1, A13, A14, X12 are defined in the specification.
US08741541B2 Compound, resin, photoresist composition, and method for producing photoresist pattern
A compound represented by formula (I): wherein T1 represents a single bond or a C6-C14 aromatic hydrocarbon group, L1 represents a C1-C17 divalent saturated hydrocarbon group in which a methylene group may be replaced by an oxygen atom or a carbonyl group, L2 and L3 each independently represent a single bond or a C1-C6 divalent saturated hydrocarbon group in which a methylene group may be replaced by an oxygen atom or a carbonyl group, ring W1 and ring W2 each independently represent a C3-C36 hydrocarbon ring, R1 and R2 each independently represent a hydrogen atom, a hydroxyl group, or C1-C6 alkyl group, R3 and R4 each independently represent a hydroxyl group, or C1-C6 alkyl group, R5 represents a hydroxyl group or a methyl group, m represents 0 or 1, and t and u each independently represent an integer of 0 to 2.
US08741540B2 Hard mask composition, method of forming a pattern, and semiconductor integrated circuit device including the pattern
A hard mask composition, a method of forming a pattern, and a semiconductor integrated circuit device, the hard mask composition including a solvent; and an aromatic ring-containing compound, the aromatic ring-containing compound including at least one of a moiety represented by the following Chemical Formula 1 and a moiety represented by the following Chemical Formula 2:
US08741535B2 Laser irradiation device and method of fabricating organic light emitting display device using the same
A laser irradiation device and a method of fabricating an organic light emitting display device (OLED) using the same are disclosed. The laser irradiation device includes: a laser source generating a laser beam; a mask disposed below the laser source and patterning the beam and a projection lens disposed below the mask and determining magnification of the laser beam through the mask, wherein the laser beam penetrating the mask has different doses in at least two regions. Thus, the laser irradiation device can maximize emission efficiency and enhance the quality of a transfer layer pattern when an organic layer of the OLED is formed using the laser irradiation device.
US08741533B2 Method of manufacturing toner
A method of manufacturing toner is provided. The method includes preparing a first liquid by dissolving or dispersing toner components in an organic solvent, preparing a second liquid by emulsifying the first liquid in an aqueous medium, and evaporating the organic solvent from the second liquid. The toner components include a colorant, a release agent, and one or both of a binder resin and a precursor thereof. The evaporating includes flowing down the second liquid as a liquid film in substantially a vertical direction along an inner wall surface of a pipe that is depressurized, heating the liquid film at a temperature not higher than a glass transition temperature of the binder resin, and supplying the pipe with a depressurized water vapor from a supply opening disposed on an upper part of the pipe.
US08741532B2 Toner with improved charging
The disclosure describes a toner process in which portion-wise addition of colorant(s) during particle formation is used to control the distribution of colorant within the toner particle, thereby enhancing A zone charge.
US08741530B2 Image forming apparatus
A method of forming an image on a substrate with an electrophotographic photoreceptor and a toner, a photosensitive layer of the electrophotographic photoreceptor contains a resin having a structural unit represented by the following formula (A) the toner containing toner matrix particles formed in an aqueous medium; the toner has a volume median diameter (Dv50) of from 4.0 μm to 7.0 μm; and the relationship between the volume median diameter (Dv50) and the percentage in number (Dns) of toner particles having a particle diameter of from 2.00 μm to 3.56 μm satisfies following formula (1) Dns≦0.233EXP(17.3/Dv50)  (1).
US08741525B2 Resin coated carrier, two-component developer, developing device and image forming apparatus
The resin coated carrier is used with a toner in which an external additive having an average primary particle size of 50 nm or more is added to a toner particle, and has a carrier core and a resin coating layer on the surface of the carrier core. In the resin coated carrier, the following expression (1) is satisfied: 0.5≦−log {(A/C)/(B/C)}≦2.5  (1) wherein A represents a volume resistance value (Ω/cm) of the resin coated carrier in an electric field of 1000 V/cm that is obtained by conducting a stirring test, B represents a volume resistance value (Ω/cm) of the resin coated carrier in an electric field of 1000 V/cm before the stirring test, and C represents a volume resistance value (Ω/cm) of the carrier core in an electric field of 1000 V/cm.
US08741523B2 Toner for developing electrostatic image and manufacturing method thereof
A toner for developing electrostatic image comprising a toner particle containing a binding resin is disclosed. which, and In the toner the binding resin has a domain-matrix structure composed of a high elastic resin composing a domain and a low elastic resin composing a matrix, an arithmetic mean value of ratio (L/W) of the Length L to Width W of the domains is 1.5 to 5.0, domains having Length L in the range of 60 to 500 nm exist 80 number % or more, and domains having Width Win the range of 45 to 100 nm exist 80 number % or more, in a viscoelastic image of a cross section of the toner particle observed via an atomic force microscope.
US08741515B2 Image holding member for image forming apparatus, process cartridge, and image forming apparatus
Provided is an image holding member for an image forming apparatus including a support; and a photosensitive layer disposed on the support and containing a compound represented by the following formula (I): wherein in the formula (I), R1's each independently represent a substituted or unsubstituted, linear or branched alkyl group having from 1 to 8 carbon atoms; Ar's each independently represent a substituted or unsubstituted phenyl group, a substituted or unsubstituted monovalent polynuclear aromatic hydrocarbon group having two aromatic rings, a substituted or unsubstituted monovalent condensed aromatic hydrocarbon group having two or three aromatic rings, or a substituted or unsubstituted monovalent aromatic heterocyclic group; and n's each independently represent a number of from 0 to 7.
US08741512B2 Additive for electrophotographic photoreceptor, electrophotographic photoreceptor, process cartridge, and image forming apparatus
Provided is an additive for an electrophotographic photoreceptor which is represented by Formula (I): wherein, A represents an m-valent organic group derived from arylamine represented by Formula (II) or Formula (III); T represents a divalent hydrocarbon group having from 1 to 10 carbon atoms; Rf represents a branched hydrocarbon group having from 3 to 10 carbon atoms in which at least one hydrogen atom is substituted with a fluorine atom; l represents 0 or 1; and m represents an integer of 1 to 4: wherein, Ar1, Ar2, and Ar3 each independently represent a substituted or unsubstituted aryl group having from 6 to 20 carbon atoms; Ar4, Ar5, Ar6, and Ar7 each independently represent a substituted or unsubstituted aryl group having from 6 to 20 carbon atoms; and X represents a divalent organic group represented by Formula (IV), Formula (V), or Formula (VI):
US08741511B1 Determination of lithography tool process condition
A method for forming an integrated circuit (IC) is presented. The method includes providing a wafer having a substrate prepared with a photoresist layer. The photoresist layer is processed by passing a radiation from an exposure source of a lithography tool through a mask having a pattern. The process parameters of the lithography tool are determined by performing a pattern matching process. The photoresist layer is developed to transfer the pattern on the mask to the photoresist layer.
US08741506B2 Mask and repairing method therefor
The present invention provides a mask and a repairing method therefor. A reference area is selected in a configuration pattern of a mask template, the reference area is corresponding to a to-be-shaded area of a mask; a repair area is formed on a drillable member according to the reference area; a hollow area is formed in the repair area of the drillable member, the hollow area is corresponding to the to-be-shaded area; the drillable member is attached to the mask, the hollow area is corresponding to the to-be-shaded area; and shading material is coated on the drillable member, so as to form a shaded layer on the to-be-shaded layer.
US08741505B2 Device and method for stacking fuel cell stack
Disclosed is a device and method for stacking a fuel cell stack, which enables automated accurate stacking of components constituting the fuel cell stack by using a phosphor coated thereon. Accordingly, when a membrane-electrode assembly (MEA), a separation plate, etc. are automatically stacked in sequence they are coated with phosphor at a predetermined position on each of the MEA, the separation plate, etc. A phosphor sensor is then positioned and configured to automatically determine whether or not the MEA and separator have been accurately stacked by detecting the presence of phosphor on the stacked MEA and separator plate respectively.
US08741500B2 Fuel cell stack and fuel cell system
A fuel cell stack formed by stacking two or more fuel cell layers each constituted of one or more unit cell and a fuel cell system including the same are provided. Any two fuel cell layers adjacent to each other each have one or more gap region. At least a part of the gap region in one fuel cell layer of any two fuel cell layers adjacent to each other is in contact with a unit cell constituting the other fuel cell layer. The gap region in one fuel cell layer and the gap region in the other fuel cell layer communicate with each other. The fuel cell stack is excellent in fuel or oxidizing agent supply performance and it realizes high power density.
US08741499B2 Solid oxide fuel cell
The solid oxide fuel cell of the present invention has a substrate (1); an electrolyte (3) that is disposed on one surface of the substrate (1); and at least one electrode element E having an anode (5) and a cathode (7) disposed on the same surface of the electrolyte (3) with a predetermined space therebetween.
US08741496B2 Fuel cell system with dilution and purge control and control method thereof
The object of the present invention is to provide a fuel cell system enabling an improvement in fuel consumption and a method for controlling thereof. A fuel cell system 1 includes a fuel cell 10, an air pump 21, an air supply channel, a hydrogen supply channel, a hydrogen tank, a hydrogen discharge channel, a hydrogen reflux channel, an air discharge channel, a purge valve 441, and a control device 30. The control device 30 includes a dilution judgment portion 31 judging whether dilution of hydrogen gas has been completed; an air increase portion 33 for increasing an air mass in the air discharge channel; a power production calculation portion 34 calculating an amount of power production based on the air mass increased; and a fuel cell drive portion 35 driving the fuel cell 10 to produce electric power to obtain the amount of power production calculated.
US08741493B2 Fuel production system
A fuel production system and has an object to provide a fuel production system that is capable of producing HC with high efficiency by using variable energy. A first device is a CO/H2 generating device that simultaneously generates CO and H2 by performing electrolysis on CO2 and water. A second device is a H2 generating device that generates H2 by performing electrolysis on water. When electric power derived from natural energy is used, the first device is seriously affected by its variation. Therefore, a steady-state portion of generated electric power (straight line in a figure) is supplied to the first device while the remaining variable portion (the portion above the straight line) is supplied to the second device.
US08741492B2 Lithium air battery
A main object of the present invention is to provide a lithium air battery which can use different battery properties according to the current density at the time of discharge. The present invention attains the object by providing a lithium air battery comprising a cathode layer, an anode layer, and an electrolyte layer formed between the cathode layer and the anode layer, characterized in that the cathode layer further comprises a first cathode layer having at least oxygen reduction ability and a second cathode layer having at least Li ion storage ability, and the second cathode layer contains a cathode active material having an average voltage of less than 2.0 V (vs. Li) or an average voltage of more than 2.9 V (vs. Li).
US08741490B2 Thickening agent for alkaline battery, and alkaline battery
Provided are a thickening agent for an alkaline battery, which can satisfactorily retain long-term discharge characteristics (discharge quantity and discharge time) and provide excellent impact resistance, and an alkaline battery used therewith. In the invention, the thickening agent for an alkaline battery comprises (A) a crosslinked polymer comprising, as essential constituent units, (a1) a water-soluble vinyl monomer and/or (a2) a vinyl monomer being converted into (a1) by hydrolysis, (b) a hydrolyzable crosslinking agent undergoing alkaline hydrolysis, and (c) a non-hydrolyzable crosslinking agent not undergoing alkaline hydrolysis, wherein (b) and (c) each has a content of 0.05% to 1% by weight based on the weight of (A), and satisfies Requirements (1) and (2) described below: Requirement (1): the weight ratio (b)/(c) between (b) and (c) is from 1.0 to 5.0; Requirement (2): a specific solution (S1) has a viscosity of 25 to 100 Pa·s at 25° C.
US08741488B2 Electrode including Si-containing material layer and porous film, and lithium battery employing the same
An electrode which has a Si-containing material layer and a porous film, and a lithium battery employing the same. In the electrode, the Si-containing material layer is applied on an electrode current collector and/or an electrode active material to protect the surface of the electrode current collector from oxidation. Also, the applied Si-containing material layer enhances the adhesion between the electrode current collector and the electrode active material to improve cycle life characteristics. Also, it increases the adhesion between the electrode active material and the porous film to reduce resistance, and to improve ohmic contacts and to lower the Shottkey barrier. In addition, the electrode includes the porous film functioning as a separator, and thus can provide a battery which is safe under conditions of overcharge and heat exposure without needing an additional separator.
US08741486B1 Polymer matrix energy storage device and method of making the same
In one embodiment, an energy storage device is provided which includes a cathode and an anode with a separator therebetween. At least one of the cathode or the anode has a rigid polymer matrix with an active material and elongated electrically conducting material having ion conducting moieties bonded thereto within the polymer matrix.
US08741481B2 Anode and battery
A battery capable of obtaining superior cycle characteristics and safety is provided. The battery includes a cathode, an anode, and an electrolytic solution. The electrolytic solution is impregnated in a separator provided between the cathode and the anode. The anode has an insulative coat on an anode active material layer provided on an anode current collector. The coat contains an insulating material such as a meal hydroxide and a metal oxide. The coat is in a form of plate divided into a plurality of portions. The insulation property of the coat prevents internal short circuit. A plurality of portions of the coat prevent separation of the anode active material layer and decomposition of the electrolytic solution. Further, even when short circuit occurs, heat generation is prevented by heat absorption characteristics of the coat.
US08741475B2 Secondary battery
A secondary battery includes an electrode assembly, a collector plate electrically connected to the electrode assembly and having a bottom surface support portion facing a bottom surface of the electrode assembly, and a case surrounding the electrode assembly and the collector plate.
US08741474B2 Battery assembly
A battery assembly includes a housing having an inside surface and an outside surface. The outside surface has a bottom portion, a side portion, and a junction portion between the bottom portion and the side portion. The inside surface defines an internal cavity, and a drain aperture extends through the wall from the outside surface to the cavity at the junction portion. At least one battery cell is disposed within the cavity. A contact is coupled to the housing and is in electrical communication with the battery cell.
US08741472B2 Electric storage device
An electric storage device includes: a battery block including a chassis with a plurality of storage cells installed therein; a control unit placed on the chassis for monitoring states of the plurality of storage cells based on signals concerning their physical quantities; a plurality of wires arranged on the chassis for directing the signals to the control unit; a confining member fixed on one surface of the chassis, where the control unit is placed, for defining a route along which the plurality of wires are arranged. The confining member includes a first direction restrainer defining the route for bending the wires, withstanding a reaction force accompanying bending of the plurality of wires, and a second direction restrainer withstanding a force exerted by the plurality of wires which are inserted into the route and tend to be lifted up toward a leaving direction from the one surface of the chassis.
US08741468B2 Film-packaged electric device
To provide a film-packaged battery 1 in which battery element 2 formed by collectively joining a plurality of positive and negative extending portions 2a and 2b to positive and negative electrode leads 3a and 3b for each polarity, is surrounded by laminate films 5 and 6 which are formed by laminating at least heat fusion layer 10 and metal layer 11. Protection member 4a having a melting point lower than that of heat fusion layer 10 is arranged at least between each of joining portions 20a and 20b of positive and negative electrode extending portions 2a and 2b, and heat fusion layer 10 of laminate film 5 which layer face the each of joining portions 20a and 20b.
US08741467B2 Battery packs suitable for use with battery powered appliances
Cooling air intake port (52), cooling air exhaust port (55), and securing walls (86, 87), which contact and secure the side surfaces of one or more battery cells (72), may be defined within two battery pack housing halves (50, 80). When battery pack (99) is assembled, at least one cooling air passage (91, 92) is defined by the side surfaces of the battery cells, the interior surface of the battery pack housing, and the securing walls. The cooling air passage connects the cooling air intake port to the cooling air exhaust port. By forcing cooling air through the cooling air passage, the battery cells can be effectively and efficiently cooled.
US08741465B2 Battery cooling structure
A battery cooling structure includes: a battery provided in a luggage room of a vehicle; an air intake duct, including an air inlet open in a vehicular cabin, for supplying air in the vehicular cabin to the battery as cooling air; and a partition panel standing away from a rear seat with a clearance therebetween so as to section the luggage room and the vehicular cabin and provided with a duct hole in which the air intake duct is inserted. The partition panel is provided with an air exhaust hole for exhausting air in the luggage room to the vehicular cabin. The air exhaust hole is formed at a location spaced away from the duct hole. Such a configuration provides a battery cooling structure suppressing an adverse effect caused by exhaust of heated cooling air.
US08741461B2 Battery pack having waterproof structure
A battery pack includes terminals (33) and a lock hook (37b). The terminals (33) are fastened onto a circuit board (74) and connected to rechargeable batteries (39). The terminals are exposed externally of a casing (31). The hook (37b) protrudes from a surface of the casing (31), and holds the battery pack on a charger (100). A hook opening window (24) is open in one of the surfaces of the casing. The hook (37b) can protrude from the surface of the casing (31). A drain hole (28) is open in another surface of the casing. A partition rib (25) is arranged between a path and an electronic circuit. The path is separated from the circuit. The path extends inside the casing (31) from the window (24). The circuit is mounted on the board (74). The window (24) communicates with the hole (28) through the path.
US08741460B2 Lithium ion secondary battery
A lithium ion secondary battery includes a flat-shaped electrode wound body. Positive and negative terminals are connected respectively to the body and placed to partially protrude from a battery lid. Assuming that the body length in a winding axial direction is W, the body size in a direction perpendicular to the axial direction and parallel to the flat surfaces is H, and a distance between a farthest position in a connecting range of one of the terminals, in which the terminal is connected to an uncoated portion, from the lid and the body edge located on the lid side is X, the values W, H, and X are determined so that a point defined in a plane (X/H, H/W) by values (X/H) and (H/W) is located in a triangle defined by joining three points, (0.50, 0.70), (0.32, 0.40), and (0.70, 0.40) in the same plane.
US08741458B2 Battery with over-pressure protection
A battery assembly includes a sealed battery cell container holds a positive and negative electrode and an electrolyte. Deflection-responsive means engages at least one outer face of the container and is responsive to deflection thereof for operating a cut-off switch to break the electrical continuity of the battery assembly. Flat battery cell containers may be stacked in different arrangements within a coupling structure, the arrangements defining either a cavity between the coupling structure and an adjacent container face, or a cavity between faces of adjacent cell containers. A membrane switch received in the cavity is actuated by bulging of a cell container wall. A control circuit operates the cut-off switch in response to actuation of the membrane switch.
US08741457B2 Rechargeable lithium batteries comprising means for the sorption of harmful substances in the form of a multilayer polymeric sheet
Rechargeable lithium batteries are described comprising an airtight container, electrodes immersed in an electrolytic solution and spaced apart by means of one or more separators, electrical contacts connected to the electrodes and a means for sorbing harmful substances formed of a multilayer polymeric sheet (10) comprised of an inner layer (12) of a polymeric material containing particles (11) of one or more getter materials for the sorption of the harmful substances, and at least one external protective layer (13) of a polymeric material impermeable to the electrolyte, wherein all the polymeric materials are permeable to the harmful substances.
US08741451B2 Crystal film, crystal substrate, and semiconductor device
A crystal foundation having dislocations is used to obtain a crystal film of low dislocation density, a crystal substrate, and a semiconductor device. One side of a growth substrate (11) is provided with a crystal layer (13) with a buffer layer (12) in between. The crystal layer (13) has spaces (13a), (13b) in an end of each threading dislocation D1 elongating from below. The threading dislocation D1 is separated from the upper layer by the spaces (13a), (13b), so that each threading dislocation D1 is blocked from propagating to the upper layer. When the displacement of the threading dislocation D1 expressed by Burgers vector is preserved to develop another dislocation, the spaces (13a), (13b) vary the direction of its displacement. As a result, the upper layer above the spaces (13a), (13b) turns crystalline with a low dislocation density.
US08741443B2 Disposable food tray
A repulpable and recyclable case ready food tray is disclosed for carrying various food items, such as meat, poultry and produce that is typically used for retail display. The food tray is formed from paperboard made from natural wood fiber that is coated to provide a waterproof food cavity for preventing leakage of liquid from the food item and a moisture proof exterior support surface which allows excess liquid to be released from the food tray during the manufacturing process while providing a moisture proof surface to prevent wicking of liquid into the food tray if the tray is placed on a wet surface.
US08741440B2 Non-stick ceramic coating composition and process
A series of new non-stick ceramic coating materials prepared from organic-inorganic hybrid materials, including silica sol, MTMS, FAS and PDMS (Polydimethylsiloxane) using the sol-gel process. The hybrid materials have good mechanical properties and are fashioned into a main ceramic network and good non-stick properties from organic non-stick compounds. The non-stick ceramic coating consists of two layers applied to cookware and for other applications.
US08741439B2 Laminated glass interlayer and laminated glass
The present invention aims to provide an intermediate film for laminated glass which, in the case of being used for constituting a laminated glass, enables to improve the sound-insulating property of the obtained laminated glass, and a laminated glass. The intermediate film 1 for laminated glass of the present invention comprises a first layer 2 which contains a polyvinyl acetal resin and a plasticizer, and the polyvinyl acetal resin and the first plasticizer are a polyvinyl acetal resin and a first plasticizer which have a cloud point of 5° C. or lower when the cloud point is measured using a solution prepared by dissolving 8 parts by weight of the polyvinyl acetal resin in 100 parts by weight of the first plasticizer; and the laminated glass 11 of the present invention comprises first and second components for laminated glass, and the intermediate film 1 for laminated glass sandwiched between the first and second components for laminated glass.
US08741429B2 Fixing heater and manufacturing method thereof
A fixing heater is provided that employs, as a heating element, a material having small heat capacity and excellent wear resistance. A metal or semi-metal compound that can act as an electrical conduction inhibiting material is mixed into a carbon-containing resin such as a furan resin, chlorinated vinyl chloride resin, etc., and a pattern of a heating element is formed on a substrate, by screen printing, and then is sintered at temperature of about 1000° C. to obtain a fixing heater including amorphous carbon and having NTC characteristics.
US08741428B2 Surface-coated cutting tool and manufacturing method thereof
A surface-coated cutting tool according to the present invention includes a base material and a coating film formed on the base material. The coating film includes at least one TiCN layer. The TiCN layer has a columnar crystal region. The columnar crystal region is characterized by having a composition of TiCxNy(in which 0.65≦x/(x+y)≦0.90), having a (422) plane having a plane spacing of 0.8765 Å to 0.8790 Å and having TC (220) showing a maximum value in an orientation index TC (hkl).
US08741426B2 Blends comprising epoxy resins and mixtures of amines with guanidine derivatives
The present invention provides a blend comprising one or more epoxy resins and a mixture which comprises 0.3 to 0.9 amine equivalent, per equivalent of epoxide of the epoxy resin used, of a hardener component a) and as hardener component b) a compound of the formula I, a process for preparing this blend, the use of the blend of the invention for producing cured epoxy resin, and an epoxy resin cured with the blend of the invention.
US08741425B2 All ceramics solid oxide fuel cell
The present invention provides an all ceramics solid oxide cell, comprising an anode layer, a cathode layer, and an electrolyte layer sandwiched between the anode layer and the cathode layer, wherein the electrolyte layer comprises doped zirconia and has a thickness of from 40 to 300 μm; wherein the anode layer and the cathode layer both comprise doped ceria or both comprise doped zirconia; and wherein the multilayer structure formed of the anode layer, the electrolyte layer and the cathode layer is a symmetrical structure. The present invention further provides a method of producing said solid oxide cell.
US08741423B2 Carbon nanotube plate and application thereof
A carbon nanotube plate is provided. The plate includes a first carbon nanotube layer composed of many first carbon nanotubes and a second carbon nanotube layer disposed on the first carbon nanotube layer. The second carbon nanotube layer is composed of many second carbon nanotubes placed in an orderly manner on the first carbon nanotube layer. At least two second carbon nanotubes are located along a curve. The surface of the second carbon nanotube layer has a whirlpool pattern.
US08741420B2 Component and methods of fabricating and coating a component
A component is disclosed. The component comprises a substrate comprising an outer surface and an inner surface, where the inner surface defines at least one hollow, interior space, where the outer surface defines one or more grooves, and where each of the one or more grooves extends at least partially along the surface of the substrate and has a base. One or more access holes extend through the base of a respective groove to place the groove in fluid communication with respective ones of the at least one hollow interior space. The component further comprises a coating disposed over at least a portion of the substrate surface, where the coating comprises one or more layers. At least one of the layers defines one or more permeable slots, such that the respective layer does not completely bridge each of the one or more grooves. The grooves and the coating together define one or more channels for cooling the component.
US08741419B2 Nanocarbon material-composite substrate and manufacturing method thereof
Disclosed is a nanocarbon material-composite substrate including a substrate, a three-dimensional structural pattern formed on the substrate, and a nanocarbon material formed on a surface of the substrate, wherein the nanocarbon material is disposed at least on side surfaces of the three-dimensional structural pattern.
US08741417B2 Films having switchable reflectivity
Compositions, structures and methods that relate to films having switchable reflectivity and anti-reflectivity depending on ambient conditions, such as temperature. A film with switchable reflectivity and anti-reflectivity includes a nanostructured first layer having nanopillars associated with nanowells. A hydrogel occupies at least a portion of the nanowells. As the hydrogel moves from a dehydrated state to a hydrated state, the surface of the film switches from being reflective to being anti-reflective in a repeatable and reversible process.
US08741414B2 Sheet for producing a multilayer optical recording medium and multilayer optical recording medium
A sheet for producing a multilayer optical recording medium having a repeated structure in which a plurality of optical recording layers are laminated, wherein the sheet has a structure such that a unit comprising at least a release assisting layer, an optical recording layer having a thickness of 1 to 1,000 nm and a pressure sensitive adhesive layer are disposed on a process film, the release assisting layer is disposed on the surface of the process film, and a pressure sensitive adhesive layer is disposed as the outermost layer, and an absolute value of difference between refractive indices of the release assisting layer and the pressure sensitive adhesive layer at a wavelength of 660 nm is 0.11 or smaller; and a multilayer optical recording medium obtained by using the sheet. The sheet enables to release the process film and transfer the optical recording layer while the condition of the surface of the optical recording layer is kept excellent. The multilayer optical recording medium has a great recording density and exhibits excellent property for recording.
US08741411B2 Multi-piece board and method for manufacturing the same
A method for manufacturing a multi-piece board having a frame section and a multiple piece sections connected to the frame section includes forming a frame section from a manufacturing panel for the frame section, sorting out multiple acceptable piece sections by inspecting quality of piece sections, forming notch portions in the frame section and the acceptable piece sections such that the notch portions allow the acceptable piece sections to be arranged with respect to the frame section, provisionally fixing the piece sections and the frame section in respective positions, injecting an adhesive agent into cavities formed by the notch portions when the frame section and the piece sections are provisionally fixed to each other, and joining the acceptable piece sections with the frame section by curing the adhesive agent injected into the cavities.
US08741401B2 Recording medium
A recording medium includes a support; and an ink-receiving layer, the ink-receiving layer having a lower layer and an upper layer, in which the lower layer contains fine inorganic particles, polyvinyl alcohol, and boric acid, the fine inorganic particles including at least one compound selected from alumina, hydrated alumina, and vapor-phase-process silica, in which the upper layer contains fine inorganic particles, polyvinyl alcohol, and boric acid, the fine inorganic particles including at least one compound selected from alumina and hydrated alumina, in which the lower layer has a boric acid content of 2.0% by mass to 7.0% by mass with respect to polyvinyl alcohol, and in which the upper layer has a boric acid content of 10.0% by mass to 30.0% by mass with respect to polyvinyl alcohol.
US08741397B2 Liquid crystal display element, liquid crystal composition, aligning agent, method for producing liquid crystal display element, and use of liquid crystal composition
Disclosed is a liquid crystal display element which is composed of a pair of substrates (1) at least one of which is transparent. The liquid crystal display element comprises, between the pair of substrates, a transparent electrode (2), an aligning agent (3) that contains at least reactive monomers and/or oligomers (5), and a liquid crystal layer. The liquid crystal display element is characterized in that an alignment layer is obtained by polymerizing the reactive monomers or oligomers contained in the aligning agent, and the liquid crystal layer is composed of a liquid crystal composition that contains a compound (4) having at least one benzene ring in each molecule, said benzene ring containing at least one fluorine atom and being disubstituted by halogen atoms.
US08741396B2 Method for forming amorphous carbon nitride film, amorphous carbon nitride film, multilayer resist film, method for manufacturing semiconductor device, and storage medium in which control program is stored
An amorphous carbon film, which has excellent etching resistance and is capable of reducing reflectance when a resist film is exposed to light, is form. A method for manufacturing a semiconductor device includes forming an object film to be etched on a wafer, supplying a process gas containing a CO gas and an N2 gas into a processing container, forming an amorphous carbon nitride film from the supplied CO gas and N2 gas, forming a silicon oxide film on the amorphous carbon nitride film, forming an ArF resist film on the silicon oxide film, patterning the ArF resist film, etching the silicon oxide film by using the ArF resist film as a mask, etching the amorphous carbon nitride film by using the silicon oxide film as a mask, and etching the object film to be etched by using the amorphous carbon nitride film as a mask.
US08741395B2 Apparatus and method for carbon fiber surface treatment
An apparatus and method for enhancing the surface energy and/or surface chemistry of carbon fibers involves exposing the fibers to direct or indirect contact with atmospheric pressure plasma generated using a background gas containing at least some oxygen or other reactive species. The fiber may be exposed directly to the plasma, provided that the plasma is nonfilamentary, or the fiber may be exposed indirectly through contact with gases exhausting from a plasma discharge maintained in a separate volume. In either case, the process is carried out at or near atmospheric pressure, thereby eliminating the need for vacuum equipment. The process may be further modified by moistening the fibers with selected oxygen-containing liquids before exposure to the plasma.
US08741394B2 In-situ deposition of film stacks
Methods for depositing film stacks by plasma enhanced chemical vapor deposition are described. In one example, a method for depositing a film stack on a substrate, wherein the film stack includes films of different compositions and the deposition is performed in a process station in-situ, is provided. The method includes, in a first plasma-activated film deposition phase, depositing a first layer of film having a first film composition on the substrate; in a second plasma-activated deposition phase, depositing a second layer of film having a second film composition on the first layer of film; and sustaining the plasma while transitioning a composition of the plasma from the first plasma-activated film deposition phase to the second plasma-activated film deposition phase.
US08741393B2 Method for producing metalized fibrous composite sheet with olefin coating
A composite sheet is manufactured by depositing a multi-layer coating on the outer surface of a substrate, the coating comprising a metal layer and an outer polymeric layer formed from a precursor comprising a composition capable of being polymerized and/or cross-linked by free-radical processes. After the precursor is applied, the composite sheet is exposed to beam radiation and ozone, which both promote conversion of the precursor. The function of the cured polymeric layer includes protecting the metal layer from corrosion. The use of both beam radiation and ozone promotes substantially full conversion and curing of the precursor, even in portions of the substrate that are geometrically shadowed from incident beam radiation.
US08741392B2 Anodically assisted chemical etching of conductive polymers and polymer composites
A novel activation/etch method is disclosed for conductive polymer substrates and conductive polymer composite substrates to achieve good adhesion to subsequently applied coatings. The method in a preferred case involves anodically polarizing conductive polymers/polymer composites in aqueous etching solutions.
US08741388B2 Compositions and methods for providing coatings; materials; application techniques; and, resulting coated substrates
Techniques and compositions for applying films to a variety of substrates, from water-borne coating compositions, are provided. The techniques involve providing desiccant and applying the desiccant with water-borne film-forming composition, in application to a substrate. The desiccant composition provides for take up of free water in of the film-forming composition, without total reliance on ambient conditions, to advantage. Compositions, methods, techniques and resulting constructions are described. The techniques can be applied in wet thick film applications, but are not limited to such applications.
US08741384B2 Method of synthesizing branched gold nanoparticles having controlled size and branching
A method of synthesizing branched gold nanoparticles is described, starting from an aqueous solution of gold nanoparticle spherical seeds, which is subjected to a growth treatment with an aqueous solution comprising hydroxylamine or a salt thereof as a reducing agent and 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) as an agent that directs the shape of the nanostructure, and by subsequent addition of an aqueous solution of chloroauric acid (HAuCl4). The structural features and the properties of the branched gold nanoparticles obtained by the method of the invention are also described.
US08741383B2 Method of producing optical film and coating liquid for production of optical film
Provided is a method of producing an optical film which has an excellent strength and a low refractive index, and can be used for an optical antireflective film. The production method includes preparing a coating liquid including a capsule having a shell of a halogenated compound of an element of Group 2 by forming an emulsion of one of an aqueous solution including a compound containing an element of Group 2 and an aqueous solution including a compound containing a halogen, and an organic solvent, applying the coating liquid on a substrate, and heating the coating liquid, thereby forming an optical film containing a hollow particle having the shell of a halogenated compound of an element of Group 2.
US08741379B2 Rotatable support elements for stents
Various embodiments of methods and devices for coating stents are described herein.
US08741378B1 Methods of coating an implantable device
Methods of coating an implantable device, such as a stent, are provided.
US08741375B2 Mixed amino acid metal salt complexes
A mixed amino acid metal salt complex of the mixed amino acids, lysine and glutamic acid associated with trace metals selected from the group consisting of iron, manganese, copper and zinc to provide highly bioavailable sources of the iron, manganese, copper and zinc and as well to take advantage of the different amino acid transport pathways of lysine and glutamic acid.
US08741369B2 Microwaveable dough compositions
Microwavable dough compositions are provided that are effective for providing products with improved texture using microwave heating. More specifically, the microwavable dough compositions include a blend of fiber, hydrocolloid, methylcellulose and functional surfactants in amounts that are effective for providing a cooked dough having improved firmness for an extended time after microwave cooking.
US08741368B2 Method and apparatus for deep-frying foods
A method for deep-frying foods in which the foods to be deep-fried are delivered to hot oil or fat and transported out of the hot oil after a predetermined residence time, wherein a steam zone with superheated steam is generated above a free surface of the oil, which shields the oil from the ambient air, and from which a flow of steam corresponding to an amount of water evaporating from the deep-fried foods is withdrawn.
US08741367B2 Food product forming apparatus and process
The present invention is related to a food product-forming apparatus, with a movable form-body, in which the food product is formed, and a knock out cup, which executes a knock-out-movement, that removes the food product from the form-body, whereas the knock out cup comprises an at least partially permeable bottom, through which a fluid-medium can be ejected and whereas, during the knock-out movement, a fluid-medium cushion is created, at least temporarily beneath the permeable bottom. The present invention furthermore comprises a process for the production of food products.
US08741363B2 Surfactant-containing preparation comprising licochalcone A
Cosmetic hair- and/or body-cleansing compositions comprising licochalcone A or an extract of Radix Glycyrrhiza inflata and one or more surfactants and, optionally, further comprising cosmetic and/or dermatological active ingredients, auxiliaries and additives.
US08741358B2 Ghrelin production promoter
The objectives are to find a substance or a composition capable of promoting the production of ghrelin with physiological activities such as growth hormone secretion effect, and to provide a pharmaceutical comprising it as the active ingredient. The pharmaceutical is a ghrelin production promoter comprising Rikkunshi-to as the active ingredient.
US08741355B2 Calcium carbonate granulation
Highly compactable granulations and methods for preparing highly compactable granulations are disclosed. More particularly, highly compactable calcium carbonate granulations are disclosed. The granulations comprise powdered materials such as calcium carbonate that have small median particle sizes. The disclosed granulations are useful in pharmaceutical and nutraceutical tableting and provide smaller tablet sizes upon compression than previously available.
US08741352B2 Graft materials containing ECM components, and methods for their manufacture
Described are packaged, sterile medical graft products containing controlled levels of a growth factor such as Fibroblast Growth Factor-2 (FGF-2). Also described are methods of manufacturing medical graft products wherein processing, including sterilization, is controlled and monitored to provide medical graft products having modulated, known levels of a extracellular matrix factor, such as a growth factor, e.g. FGF-2. Preferred graft materials are extracellular matrix materials isolated from human or animal donors, particularly submucosa-containing extracellular matrix materials. Further described are ECM compositions that are or are useful for preparing gels, and related methods for preparation and use.
US08741348B2 Physically and chemically stable nicotine-containing particulate material
A nicotine-containing particulate material for release of nicotine, the material comprising a combination of nicotine or a pharmaceutically acceptable salt, complex or solvate thereof and a microcrystalline cellulose. The particulate material is stable upon storage and releases nicotine relatively fast. The particulate material can be used in the manufacture of nicotine containing pharmaceutical composition, wherein the release of nicotine can be designed to be relatively fast so as to obtain a fast onset of action.
US08741347B2 Method for forming cyclodextrin polymer and lipophilic compound emulsions, resulting emulsions, and compositions including said emulsions
The present invention relates to a method for preparing a cyclodextrin polymer and/or a hydrophilic polymer emulsion having cyclodextrins as well as lipophilic compounds, the emulsions having a remarkable stability. In particular, the method includes: (i) adding a lipophilic compound into an aqueous solution of a cyclodextrin unit polymer or hydrophilic polymer having cyclodextrins; (ii) forming an emulsion from the mixture resulting from step (i). The invention also relates to the resulting emulsions, i.e. stabilized emulsions by a non-covalent and non-crystalline inclusion complex consisting of (i) a cyclodextrin unit polymer or a hydrophilic polymer having cyclodextrins and (ii) a lipophilic compound. The invention also relates to the use of said emulsions in the cosmetic, pharmaceutical and/or agri-food fields.
US08741345B2 Modified release pharmaceutical compositions of dexlansoprazole
Modified release oral pharmaceutical compositions of dexlansoprazole or pharmaceutically acceptable salts or hydrated forms thereof in the form of a bilayer tablet and processes for the manufacture of the tablet composition and its use in the treatment of gastrointestinal disorders.
US08741344B1 Dispersible tablet
The present invention relates to a tablet comprising Nimorazole. In particular, the invention concerns a pharmaceutical composition or a tablet comprising Nimorazole or a pharmaceutically acceptable salt, for dispersion in water and administration via a tube to a patient with swallowing difficulties.
US08741341B2 Manufacturing and packaging room temperature stable dronabinol capsules
The invention provides a method of manufacturing and packaging a room temperature stable cannabinoid dosage in an oil-based carrier, wherein the method employs the use of blister packaging and an inert gas atmosphere during blister packaging. The invention also provides a room temperature stable cannabinoid dosage prepared by the methods of the invention.
US08741339B2 Active targeting polymer micelle encapsulating drug, and pharmaceutical composition
The present invention provides an active targeting polymer micelle encapsulating a drug, preventing an inappropriate release of a drug which may damage a normal cell. A polymer micelle 100 includes a backbone polymer unit 10 that has a target binding site 11 and a backbone polymer unit 20 that has a drug 14 and is free from the target binding site 11, such polymer units 10 and 20 being disposed in a radial arrangement in a state where the target binding site 11 is directed outward and the drug 14 is directed inward, in which: i) when the micelle is bound to a target 40 while maintaining the radial arrangement, the micelle is taken up into a cell 50 supplying the target 40 through endocytosis, and the drug 14 is released into the cell 50 by collapse of the radial arrangement in the cell 50; and ii) when the radial arrangement collapses in blood 60 before the micelle is bound to a target 40, the unit 20 is excreted through metabolism, to thereby prevent a normal cell from being damaged by the drug 14.
US08741338B2 Targeted delivery to human diseases and disorders
The present invention provides a system presenting site-specific accumulation through a ligand that specifically targets a receptor overexpressed on the surface of specific cells within a target organ, like, for example, tumor cells and/or vascular cells of tumor blood vessels. Moreover, this invention provides a method where, upon internalization of the previous-mentioned system by the target cells, triggered release at a high rate of the associated agent takes place, permitting efficient intracellular delivery and, thus, increased concentration of the transported cargo at the target site. Overall, this invention provides a method for the diagnosis, prevention and treatment of human diseases and disorders.
US08741336B2 Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, Alzheimer'S disease, sleep disorders, Parkinson'S disease, AIDS, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
Systems and methods for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and treating hyperglycemia, Alzheimer's disease, sleep disorders, Parkinson's disease, Attention Deficit Disorder and nicotine addiction involve synchronizing and tailoring the administration of nutraceuticals, medications and other substances (for example, stimulants) in accordance with the body's natural circadian rhythms, meal times and other factors. Improved control of blood glucose levels, extended alertness, and weight control, and counteracting of disease symptoms when they are at their worst are possible. An automated, pre-programmable transdermal administration system is used to provide pulsed doses of medications, pharmaceuticals, hormones, neuropeptides, anorexigens, pro-drugs, stimulants, plant extracts, botanicals, nutraceuticals, cosmeceuticals, phytochemicals, phytonutrients, enzymes, antioxidants, essential oils, fatty acids, minerals, vitamins, amino acids, coenzymes, or other physiological active ingredient or precursor. The system can utilize a pump, pressurized reservoir, a system for removing depleted carrier solution, or other modulated dispensing actuator, in conjunction with porous membranes or micro-fabricated structures.
US08741335B2 Hemostatic compositions, assemblies, systems, and methods employing particulate hemostatic agents formed from hydrophilic polymer foam such as Chitosan
Improved hemostatic agents take the form of granules or particles that can be used to stanch, seal, or stabilize a site of hemorrhage, including a noncompressible hemorrhage.
US08741333B2 Compositions and methods for treating dermatitis or psoriasis
The present invention is drawn to adhesive solidifying formulations for treating skin disorders, such as dermatitis or psoriasis. The formulation can include a drug, a solvent vehicle, and a solidifying agent. The solvent vehicle can include a volatile solvent system including at least one volatile solvent, and a non-volatile solvent system including at least one non-volatile solvent, wherein the non-volatile solvent system is capable of facilitating the delivery of the drug at therapeutically effective rates over a sustained period of time. The formulation can have a viscosity suitable for application to a skin surface prior to evaporation of the volatile solvents system. When applied to the skin, the formulation can form a solidified layer after at least a portion of the volatile solvent system is evaporated.
US08741332B2 Compositions and methods for dermally treating neuropathic pain
The present invention is drawn to adhesive solidifying formulations for treating neuropathic pain. The formulation can include a drug suitable for treating neuropathic pain, a solvent vehicle, and a solidifying agent. The solvent vehicle can include a volatile solvent system including at least one volatile solvent, and a non-volatile solvent system including at least one non-volatile solvent capable of facilitating the delivery of the drug at therapeutically effective rates over a sustained period of time. The formulation can have a viscosity suitable for application to a skin surface prior to evaporation of the volatile solvents system. When applied to the skin, the formulation can form a solidified layer after at least a portion of the volatile solvent system is evaporated.
US08741330B2 Transluminal drug delivery methods and devices
Transluminal drug delivery method and device embodiments can include a urethral suppository formulated to prevent or treat diseases of the urethra and surrounding organs, such as interstitial cystitis or urethritis, by enhancing the absorption of a therapeutic agent of the suppository into body tissues without adversely affecting the natural defense mechanisms of these tissues. Adverse effects on the glycosaminoglycan (GAG) barrier can be mitigated or eliminated by the presence of a suitable polysaccharide in the suppository.
US08741326B2 Modified two-component gelation systems, methods of use and methods of manufacture
A bioscaffolding can be formed from a mixture of gel components of different gelation systems. For example, a bioscaffolding can be formed by mixing at least two different components of at least two different two-component gelation systems to form a first mixture and by mixing at least two different components (other than the components that make up the first mixture) of the at least two different two-component gelation systems to form a second mixture. A treatment agent, such as a cell type or a growth factor, can be added to either the first mixture or the second mixture. In some embodiments, the treatment agent is not added to either mixture. The first mixture can be co-injected with the second mixture to form a bioscaffolding in an infarct region for treatment thereof.
US08741321B2 Capsule whose envelope is separately imperceptible during the topical use thereof
A capsule for cosmetic and/or dermatological ingredients and processes for the production thereof. The capsule comprises an envelope which is solid, semisolid and/or dimensionally stable and comprises one or more substances which are selected from waxes, emulsifiers, and natural and synthetic polymers. The capsule may also comprise a filling.
US08741318B2 Multicomponent and biocompatible nanocomposite materials, methods of synthesizing same and applications of same
One aspect of the present invention relates to a method of synthesizing a multicomponent and biocompatible nanocomposite material, which includes: synthesizing a gold/hydroxyapatite (Au/HA) catalyst; distributing the Au/HA catalyst into a thin film; and heating the thin film in a reactor with a carbon source gas to perform radio frequency chemical vapor deposition (RF-CVD) to form the nanocomposite material, where the nanocomposite material includes a graphene structure and Au/HA nanoparticles formed by the Au/HA catalyst and distributed within the graphene structure. In another aspect, a multicomponent and biocompatible nanocomposite material includes: a graphene structure formed with a plurality of graphene layers and Au/HA nanoparticles distributed within the graphene structure. The nanocomposite material is formed by heating an Au/HA catalyst thin film with a carbon source gas to perform radio frequency chemical vapor deposition (RF-CVD).
US08741315B2 Methods of treating tumors in immune-privileged sites
A method of treating cancer in an immune-privileged site of a subject in need thereof is provided. The method comprises systemically administering to an area outside the immune-privileged site of the subject, a therapeutically effective amount of naive, viable cells of a tumor of the subject, the tumor being in the immune-privileged site so as to generate an immune response in the subject, thereby treating the cancer in the immune-privileged site of the subject.
US08741307B2 Hybrid prokaryotic-eukaryotic tubulins and use thereof
The present invention embraces hybrid Prosthecobacter-eukaryotic tubulin proteins and use thereof for identifying agents that modulate the activity of tubulin.
US08741305B2 Protein composition for inducing an immune response in a vertebrate comprising a plurality of protein variants covering the heterogeneity of a single antigen, AMA1
The present invention relates to a protein composition suitable for inducing an immune response in a vertebrate comprising 2 to 10 protein variants of a single antigen, which is the APICAL MEMBRANE ANTIGEN 1 (PfAMA1 OR AMA1) of a Plasmodium species. The antigen comprises a plurality of variable amino acid positions, wherein the amino acid sequences of said protein variants, in combination, represent both the frequency of occurrence of each amino acid at said variable amino acid positions and the linkage between the variable amino acid positions, and wherein said frequency of occurrence is at least between 10% to 20% such as 10%, 11%, 12%, 13%, . . . , 20% in the single antigen, and wherein at least 75% of the linkages between the variable amino acid position is presented by the combination of protein variants.
US08741304B2 Chimeric vaccine for Haemophilus influenzae-induced disease
The invention described herein relates to a chimeric protein comprising the NTHi twitching pilus major subunit protein (PilA) presenting a portion of the NTHi OMP P5 protein. The invention provides for vaccine compositions comprising the recombinant chimeric protein and methods of eliciting an immune response using the recombinant chimeric proteins of the invention.
US08741302B2 Polypeptide derived from Enterococcus and its use for vaccination
A medicament for the treatment or the prevention of a bacterial infection is disclosed which contains a polypeptide having a contiguous sequence of at least six amino acids of SEQ ID NO:1. Said polypeptide can be used for the preparation of a vaccine against an Enterococcus infection.
US08741297B2 Preparation of isolated agonist anti-EDAR monoclonal antibodies
The present invention concerns the preparation of substantially purified agonist anti-EDAR monoclonal antibodies or isolated monoclonal antibody fragments or antigen binding portions or fragments thereof. The invention further relates to isolated agonist anti-EDAR monoclonal antibodies or isolated monoclonal antibody fragments or antigen binding portions or fragments thereof as well as their use in the treatment of X-linked hypohidrotic ectodermal dysplasia and tooth agenesis. The invention also relates to a pharmaceutical composition comprising said isolated agonist anti-EDAR monoclonal antibodies or isolated monoclonal antibody fragments or antigen binding portions or fragments thereof and to a method of treating X-linked hypohidrotic ectodermal dysplasia and tooth agenesis. Finally, the present invention concerns a pharmaceutical kit comprising said isolated agonist anti-EDAR monoclonal antibodies or isolated monoclonal antibody fragments or antigen binding portions or fragments thereof.
US08741295B2 PD-1 antibodies and PD-L1 antibodies and uses thereof
The invention relates to PD-1 antibodies and PD-L1 antibodies and uses thereof.
US08741287B2 PlGF-1 assay and kits and components thereof
The present disclosure relates to glycosylated and deglycosylated human PlGF-1, methods of using the glycosylated and deglycosylated human PlGF-1, antibodies that bind to human PlGF-1, methods of using the antibodies and human PlGF-1 immunoassays and kits.
US08741286B2 Serene protease derivatives and uses in the prevention or the treatment of blood coagulation disorders
The present invention relates to chimeric derivatives of serine protease zymogen containing the activation peptide of factor X or a fragment thereof for improving the half-life of said derivatives. Preferably, said chimeric derivatives are protein C and factor X derivatives. The invention also relates to said derivatives for the prevention or treatment of blood coagulation disorders.
US08741284B2 Crystallized oxalate decarboxylase and methods of use
Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate concentration using oxalate decarboxylase crystals are also disclosed. Additionally disclosed are methods of producing protein crystals.
US08741275B2 Malodor neutralizing compositions comprising undecylenic acid or citric acid
Compositions comprising undecylenic acid or citric acid and certain esters are effective for reducing malodors. The esters are in the molecular weight range of between 150-200 when the acid is undecylenic acid and in the range of between 130-230 when the acid is citric acid. These compositions can be used in perfumed products, household products and personal care products.
US08741270B2 Bonding tissues and cross-linking proteins with naphthalimide compounds
Naphthalimide compounds are used in tissue bonding and protein cross-linking applications. When activated by an activating agent, such as light in the 400-500 nm absorption range, the naphthalimide compounds form chemically-reactive species that cross-link proteins, bond connective tissues together, and bond tissues and other biomaterials together. A naphthalimide-labeled biomolecule, such as a naphthalimide-labeled chitosan, is also capable of bonding tissues without subsequent direct illumination of the contacted tissue area. The naphthalimide compounds may be used in tissue or arterial repair, stabilization of an expanded arterial wall after angioplasty, tethering pharmaceutical agents to tissue surfaces to provide local drug delivery, and for chemically bonding skin care products, sunscreens, and cosmetics to the skin.
US08741267B1 Method for treating periodontal disease
A periodontal medicament composition comprising povidone iodine, an agar carrier, and optionally a bio-compatible, radio-opaque salt, for treating periodontal disease is disclosed, along with a method for preparing the same. A method is also disclosed for delivering the periodontal medicament composition, while in a liquid state, into the periodontal pocket of a patient afflicted with periodontitis whereupon due to the unique properties of the agar carrier, it solidifies to the contours of the periodontal pocket to form a periodontal medicament implant for releasing the povidone iodine over a period of time. In addition, a prepackaged periodontal medicament delivery system for treating the periodontal disease is disclosed which comprises (i) a tubular dispensing apparatus for retaining and storing one or more treatment units of the periodontal medicament composition in a solid state, and for delivery of the composition after conversion to a liquid state to the periodontal pocket of a patient afflicted with the periodontal disease; and (ii) a funnel-shaped tubular device adapted for coupling with the dispensing apparatus to facilitate the delivery of the periodontal medicament composition into the periodontal pocket. For storage and shipping or transport, the tubular dispensing apparatus and funnel-shaped tubular device are packaged in a light-resistant container.
US08741265B2 Penetrating pharmaceutical foam
The invention relates to an alcohol-free cosmetic or pharmaceutical foam composition comprising water, a hydrophobic solvent, a surface-active agent, a gelling agent, an active component selected from the group of urea, hydroxy acid and a therapeutic enhancer and a propellant. The foam further comprises active agents and excipients with therapeutic properties having enhanced skin penetration.
US08741264B2 Self-sterilizing products
Self-sterilising products, and in particular novel products comprising phthalocyanine derivatives bound to polymers, a process for the preparation of said products and their use for preparing self-sterilising industrial and medical articles or devices, are described.
US08741263B2 Method and apparatus for kidney function analysis
A method and apparatus for determining physiological data related to an animal, such as kidney diagnostics data, is provided. The method includes injecting a mixture of a first and a second molecule into an animal (e.g., a human patient), determining a molecular ratio of the molecules, and determining the physiological data based on the molecular ratio. The apparatus includes a number of finger receiving apertures, a light generation circuit, a light detection circuit, a pulse counting circuit, and a user interface.
US08741262B2 Targeted radiotherapy
The present invention concerns a therapeutically labeled napthodianthrone or phenanthro[1,10,9,8-opqra]perylene-7,14-dione compound, which comprises a chemical element or an isotope that has an unstable nucleus and emits radiation during its decay to a stable form sufficient to destroy neighboring cells or tissues for use in a targeted radiotherapy to enhance curability of a warm-blooded animal that has been subjected to a necrosis-inducing antitumor therapy. A particular advantage of present invention is that viable rim resistant to a necrosis-inducing antitumor therapy such as vascular targeting agent (VTA) can be supplemented by one single or repeated doses of a therapeutically radiolabeled small molecule necrosis-avid chemical compound treatment to enhance the curability. Examples of necrosis inducing therapies are for instance minimally invasive tumor ablations applied chemically by percutaneous injection of ethanol or acetic acid, or physically by cryotherapy, microwave, focused ultrasound, interstitial laser therapy and radio-frequency ablation (RFA); by chemotherapies using cytotoxic agents or vascular targeting agents (VTA); and by external or internal radiotherapies.
US08741261B2 Methods for carbon isotope labeling synthesis by transition metal-promoted carbonylation via isocyanate using azides and carbon-isotope monoxide
Methods and reagents for transition metal-promoted carbonylation via isocyanate using carbon-isotope labeled carbon monoxide are provided. The resultant carbon-isotope labeled compounds are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.
US08741256B1 Preparation of lithium carbonate from lithium chloride containing brines
This invention relates to a method for the preparation of lithium carbonate from lithium chloride containing brines. The method can include a silica removal step, capturing lithium chloride, recovering lithium chloride, supplying lithium chloride to an electrochemical cell and producing lithium hydroxide, contacting the lithium hydroxide with carbon dioxide to produce lithium carbonate.
US08741255B2 Oxidation process
Peroxo-carbonates derived from molten alkali and/or Group II metal salts, particularly carbonate salts are used as catalysts in oxidation and epoxidation reactions. Transition metal compounds may be included to improve the selectivity of the reactions.
US08741254B2 Method of preparing bundle type silicon nanorod composite through electroless etching process using metal ions and anode active material for lithium secondary cells comprising the same
The present invention relates to a method of preparing a porous silicon nanorod structure composed of columnar bundles having a diameter of 50-100 nm and a length of 2-5 μm, and a lithium secondary cell using the porous silicon nanorod structure as an anode active material. The present invention provides a high-capacity and high-efficiency anode active material for lithium secondary cells, which can overcome the low conductivity of silicon and improve the electrode deterioration attributable to volume expansion because it is prepared by electrodepositing the surface of silicon powder with metal and simultaneously etching the silicon powder partially using hydrofluoric acid.
US08741251B2 Granular mesoporous silica and preparation method thereof
Disclosed are granular mesoporous silica and a preparation method thereof. The preparation method includes preparing powdered silica containing a structure derivative to form mesopores; preparing a molded precursor including the powdered silica and an inorganic binder or an organic binder; preparing a granular molded article having a predetermined shape by extruding or injection-molding the molded precursor; and removing the structure derivative by calcinating the granular molded article. The granular mesoporous silica represents superior pore characteristics and is used as an adsorbent capable of effectively removing pollutants in water treatment and air pollution treatment.
US08741250B2 Hydroxylation of icosahedral boron compounds
The present invention relates to a synthetic method for producing a per-hydroxylated icosahedral boron compound via catalytic hydroxylation of icosahedral boron compound using a soft electrophile.
US08741248B2 Ammonia salts as regenerable CO2 sorbents
The present method describes the absorbing and desorbing of a gaseous reactant on a solid reactant. The solid reactant is an ammonia salt selected from the group consisting of alkali ammonium salts, alkali ammonium earth salts or a combination thereof.
US08741245B2 Carbon dioxide-absorbing solution and method of recovering carbon dioxide
A method of recovering carbon dioxide, includes bringing gas to be processed containing carbon dioxide (CO2) and oxygen into contact with the CO2-absorbing solution in an absorption column to form a CO2-rich solution; circulating the solution in a regeneration column to thermally release and recover CO2 and recirculating the absorbing solution as a CO2-poor solution inside the absorption column; and performing heat exchange between the solution being delivered from the absorption column to the regeneration column and the solution recirculated from the regeneration column to the absorption column, wherein an alkanolamine aqueous solution containing a silicone oil and/or an organosulfur compound is added to the solution inside the absorption column and/or the solution recirculated from the regeneration column to the absorption column to adjust the composition of the absorbing solution inside the absorption column.
US08741241B2 Methods and systems for an engine emission control system
Systems and methods are provided for a layered emission control device coupled to an exhaust manifold. Various formulations may be incorporated in a plurality of layers of the device to enable various emission control functions to be grouped within spatial constraints. For example, a first layer may include a first, oxidizing catalyst, a second layer may include a HC trap, and a third layer may include a second, different oxidizing catalyst, the second layer positioned between the first and third layers. The layers may be organized to reduce functional interference and improve functional synergy between the various emission control functions.
US08741239B2 Method and apparatus for operation of CO/VOC oxidation catalyst to reduce NO2 formation for gas turbine
A power generating apparatus including a gas turbine engine combusting a fuel in air to produce shaft power and producing a flow of exhaust gases including oxides of nitrogen (NOx), carbon monoxide (CO) and hydrocarbons (HC). An emissions treatment apparatus includes in the exhaust gas flowpath a CO oxidation catalyst disposed at a location with an exhaust gas temperature for which the CO oxidation catalyst advantageously limits NO2 production. The emissions treatment apparatus further includes an ammonia injection apparatus, a mixing section, and a selective catalytic reduction element disposed downsteam of the ammonia injection apparatus and adapted for reduction of NOx.
US08741234B2 Disposable cartridge for fluid analysis
A disposable blood analysis cartridge for analyzing a blood sample including an optical absorbance measurement channel is described. The optical absorbance measurement channel includes a plasma separation region and at least one sub channel including a cuvette that is in fluid communication with the plasma separation region and configured to receive a plasma portion of a blood sample that has been passed through the plasma separation region. A negative pressure may be applied to the cartridge to draw the sample through the plasma separation region and into the sub channel including the cuvette.
US08741230B2 Systems and methods of sample processing and fluid control in a fluidic system
This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The methods and devices are particularly useful for providing point-of-care testing for a variety of medical applications.
US08741229B2 Sample analyzer, reagent information displaying method and computer program product
The present invention is to present a sample analyzer, comprising: a reagent holder for holding a first and a second reagents; a display; a display controller for controlling the display so as to display a display screen including a first information displaying region for displaying one of a plurality of reagent information regarding the first reagent and a second information displaying region for displaying one of a plurality of reagent information regarding the second reagent; and a display switch receiver for receiving a display switch instruction of reagent information displayed in each of the first and second information displaying regions, wherein the display controller switches a first reagent information displayed in the first information displaying region to a second reagent information and switches a third reagent information displayed in the second information displaying region to a fourth reagent information, when the display switch receiver has received the display switch instruction.
US08741222B2 Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
Various systems, devices, NO2 absorbents, NO2 scavengers and NO2 recuperator for generating nitric oxide are disclosed herein. According to one embodiment, an apparatus for converting nitrogen dioxide to nitric oxide can include a receptacle including an inlet, an outlet, a surface-active material coated with an aqueous solution of ascorbic acid and an absorbent wherein the inlet is configured to receive a gas flow and fluidly communicate the gas flow to the outlet through the surface-active material and the absorbent such that nitrogen dioxide in the gas flow is converted to nitric oxide.
US08741220B2 Breathing assistance apparatus
The present invention provides a breathing assistance apparatus that has a convenient and effective method of cleaning internal conduits inside the apparatus. The breathing assistance apparatus is preferably a gases supply and humidification device. The cleaning method is a method of disinfection that is automated so minimal training is required to disinfect in particular an internal elbow conduit within the device. It is therefore not necessary to dismantle the gases supply and humidification device, therefore, inadvertent damage to the internal parts of the device is avoided. The present invention also provides a method of disinfecting a heated breathing conduit and a patient interface.
US08741218B2 Automatic analyzer
An analytic method uses a labeled antigen, labeled antibody, tracer, etc. in which a radio isotope, fluorescent dye, luminescent dye, enzyme, etc. is bonded to an antibody or an antigen bonded to a protein as an object of analysis for performing an assay of a trace amount of a substance such as a hormone, tumor marker, infective pathogen marker, infective antibody, etc., for blood, serum, plasma, or body fluid as a sample or specimen. The analysis is enabled at high sensitivity, with less generation of noises and at low background. When an assay is performed based on the antigen-antibody reaction for a sample in an analytic method by fluorometry or luminometry, detection or measurement of non-specific fluorescence or luminescence such as interference light is eliminated or removed effectively irrespective of the property of the sample or the level of the concentration of substances contained in the sample.
US08741217B2 Titanium alloy for corrosion-resistant materials
There is provided a titanium alloy for corrosion-resistant materials, which contains 0.01-0.12% by mass in total of at least one of platinum group elements; at least Si and one of, or both of, Sn and Mn, selected from the group consisting of Al, Cr, Zr, Nb, Si, Sn and Mn, wherein the total content of Al, Cr, Zr, Nb, Si, Sn and Mn is 5% by mass or less; and the residue comprising Ti and impurities.
US08741212B2 Intermetallic-containing composite bodies, and methods for making same
Composite bodies made by a silicon metal infiltration process that feature a silicon intermetallic, e.g., a metal silicide. Not only does this give the composite material engineer greater flexibility in designing or tailoring the physical properties of the resulting composite material, but the infiltrant also can be engineered compositionally to have much diminished amounts of expansion upon solidification, thereby enhancing net-shape-making capabilities. These and other consequences of engineering the metal component of composite bodies made by silicon infiltration permit the fabrication of large structures of complex shape.
US08741211B2 Method for making a wafer level aluminum nitride substrate
Disclosed is a method for making a pure aluminum nitride substrate. At first, aluminum nitride is mixed with a water-resistant material and an adhesive material. The mixture is made into grains in a granulation process. The grains are molded into a nugget in a steel mode by hydraulic pressure. The nugget is subjected to a cold isostatic pressing process. At a low temperature, the water-resistant material and the adhesive material are removed from the nugget. Then, the nugget, boron nitride and nitrogen are introduced into and sintered in an oven, thus providing a pure aluminum nitride substrate. The purity and quality of the aluminum nitride substrate are high. The aluminum nitride substrate can be used in a light-emitting diode. The method is simple, the yield is high, and the heat radiation of the aluminum nitride substrate is excellent.
US08741210B2 Beta-spodumene-cordierite composition, article, and method
Porous spodumene-cordierite honeycomb bodies of high strength but low volumetric density, useful for the manufacture of close-coupled engine exhaust converters, gasoline engine particulate exhaust filters, and NOx integrated engine exhaust filters, are provided through the reactive sintering of batches comprising sources of magnesia, alumina and silica together with a lithia source, such as a spodumene or petalite ore.
US08741207B2 Method for manufacturing a plastic fuel tank comprising a built-in neck
A method for manufacturing a plastic fuel tank including a built-in neck, by molding a parison in a mold. The neck is molded by locally deforming the parison using a concave counter-form and a convex form configured to enter the counter-form, these two parts being secured one of them to the mold and the other to a core located inside the mold, or vice versa.
US08741201B2 Fiber reinforced composite stents
Polymeric composite stents reinforced with fibers for implantation into a bodily lumen are disclosed.
US08741200B2 Method of making self-supporting insulating end cone liners and pollution control devices
The invention provides a method of making a flexible and self-supporting insulating end cone liner comprising resilient and compressible non-intumescent material molded into a single, continuous piece having a three dimensional cone shape, with the insulating material comprising inorganic fibers and a binder, as well as a method of making a pollution control device that includes such an end cone liner.
US08741197B2 Antimicrobial, antifungal and antiviral rayon fibers
The invention provides an antimicrobial, antifungal and antiviral polymeric material, comprising rayon fibers and a single antimicrobial, antifungal and antiviral component consisting essentially of microscopic water insoluble particles of copper oxide incorporated in said fibers wherein a portion of said particles in said fibers are exposed and protruding from the surface of the fibers and wherein said particles release Cu++ when exposed to water or water vapor.
US08741191B2 High density powdered material liner
A method of making an explosive charge liner comprises introducing powdered material into a basin defined by a die block, where a punch is shaped to interact with the basin, excluding the powdered material from a central portion of the basin, pressing the punch into the powdered material in the basin to form the explosive charge liner, and removing the explosive charge liner from the die block. The explosive charge liner comprises an aperture in an apex area of the explosive charge liner corresponding to the central portion when removed from the die block.
US08741188B2 Ophthalmic devices comprising photochromic materials having extended pi-conjugated systems
The present invention provides ophthalmic devices comprising at least one photochromic material which is an indeno-fused naphthopyran having a pi-conjugation extending group bonded to the 11-position of the indeno-fused naphthopyran, the pi-conjugation extending group having at least one pendent halo-substituted group bonded thereto. The pi-conjugation extending group extends the pi-conjugation system of said indeno-fused naphthopyran. The 13-position of the indeno-fused naphthopyran is substantially free of spiro-substituents. The invention further provides photochromic materials of specified structure, photochromic compositions, photochromic articles and optical elements that include the photochromic materials. Other non-limiting embodiments relate to methods of making the ophthalmic devices comprising photochromic materials.
US08741186B2 Vegetable oil of high dielectric purity, method for obtaining same and use in an electrical device
A dielectric high purity vegetable oil—free from antioxidants and/or external additives to be used in electric equipment such as transformers, as isolating element and as cooling means and a method for obtaining the same in which the dielectric high purity vegetable oil—is obtained by means of the optimization of the bleaching steps—and deodorizing—from the Refining process—known as Modified Caustic Refining Long-Mix (RBD).
US08741178B2 Blue light emitting glass and preparation method thereof
Blue light emitting glass and the preparation method thereof are provided. The blue light emitting glass has the following composition: aCaO.bAl2O3.cSiO2.xCeO2, wherein a, b, c and x are, by mol part, 15-55, 15-35, 20-60 and 0.01-5 respectively. The preparation method comprises: weighing the raw materials according to the composition of the blue light emitting glass; mixing the raw materials uniformly and melting the raw materials to obtain glass melt; molding the glass melt to obtain transparent glass; thermally treating the transparent glass under reducing atmosphere, and thereafter obtaining the finished product. The blue light emitting glass obtained has intense broadband excitation spectrum in ultraviolet region and emits intense blue light under the excitation of ultraviolet light. It is suitable for using as luminescent medium material.
US08741173B2 Hydroformylation process
A combination of calixarene bisphosphite ligand and an organophosphine ligand. The combination can be employed with a catalytic metal to form a complex catalyst. The catalyst can be employed in ahydroforaiylation process for producing a mixture of aldehydes.
US08741171B2 Dedusting compositions and methods for making and using same
Compositions for reducing the formation of dust and methods for making and using same are provided. The composition can include an emulsion comprising one or more pitches, one or more fatty acids, one or more rosins, or any combination thereof. The composition can also include one or more film forming polymers, one or more oils, or a combination thereof.
US08741170B2 Ferrite particles for bonded magnet, resin composition for bonded magnet and molded products using the same
The present invention relates to ferrite particles for bonded magnet, having a volume-average particle diameter of 2.1 to 2.7 μm and a particle diameter x90 of 4.3 to 5.4 μm wherein the x90 represents a particle diameter at which a cumulative percentage of particles under sieve (undersize particles) based on a volume thereof is 90%, when determined from a particle size distribution thereof measured by using a laser diffraction type particle size distribution measuring apparatus.
US08741169B2 Heat storage composition comprising sodium sulfate decahydrate and superabsorbent
The present invention relates to a heat storage composition comprising 60-98% by weight of sodium sulfate decahydrate and 1-10% by weight of one or more superabsorbents 1-10% by weight of one or more nucleators and 0-20% by weight of one or more water-soluble salts, based in each case on the heat storage composition, said superabsorbent comprising, in polymerized form, a) at least 50 mol %, based on the superabsorbent, of one or more monoethylenically unsaturated monomers comprising acid groups, the degree of neutralization of the monoethylenically unsaturated monomers comprising acid groups being 15 to 85 mol %, and b) 0.015 to 0.1 mol %, based on the total amount of monomers, of at least one crosslinker, to a process for production thereof and to the use thereof as a heat-storing building material and as a heat storage element for motor vehicles, walls of transport vessels or other heat storage vessels.
US08741167B1 Etching composition and its use in a method of making a photovoltaic cell
This invention provides a method of making a photovoltaic cell. The method uses an etching composition comprising one or more onium salts selected from the group consisting of iodonium salts and sulfonium and an organic medium to etch the anti-reflection coating. Also provided is a photovoltaic cell made by this method.
US08741166B2 Plasma etching method
A plasma etching method that can improve an etching selection ratio of a film to be etched to a film different from the film to be etched compared with the related art is provided. The present invention provides a plasma etching method for selectively etching a film to be etched against a film different from the film to be etched, in which plasma etching of the film to be etched is performed using a gas that can cause to generate a deposited film containing similar components as components of the different film.
US08741163B2 Method for producing a composite body having a self-supporting surface
A method is provided for producing a composite body made of at least one self-supporting surface and at least one element connected to the surface in a coating process. The method includes providing a negative mold including the at least one element of the composite body, selectively ablating a surface of the negative mold to be coated with the at least one self-supporting surface by a defined first thickness so that the at least one element stands out from the surface as a projection at least in areas, depositing one or more layers for forming the at least one self-supporting surface having a defined second thickness, wherein an elevation forms in the area of the projection of the at least one element, leveling the coated surface, wherein the elevation is removed, and selectively removing at least parts of the negative mold.
US08741160B2 Method for manufacturing solar cell and solar cell manufactured by the same method
Disclosed are a method for manufacturing a solar cell by processing a surface of a silicon substrate for a solar cell, a solar cell manufactured by the method, and a substrate processing system for performing the method. The method for manufacturing a solar cell comprises protrusion forming step including wet-etching process and for forming a plurality of minute protrusions on a light receiving surface of a crystalline silicon substrate, and planarization step of planarizing the bottom surface, the opposite surface to the light receiving surface of the substrate during or after the protrusion forming step.
US08741159B2 Touch screen panel and fabricating method for the same
A method of fabricating a touch screen panel according to an embodiment of the present invention includes: forming a reinforcing layer on the top and the bottom of a glass substrate by reinforcing the entire surface of the glass substrate defining a plurality of unit cell regions; forming the touch screen panels in the unit cell regions on a side of the glass substrate with the reinforcing layers; cutting the reinforced glass substrate into the touch screen panels; forming passivation layers on the outer surfaces of the touch screen panels and sequentially stacking the touch screen panels; and simultaneously with the stacking, performing healing on the non-reinforced cut-sides of the stacked touch screen panels.
US08741156B2 Hybrid photocatalysts, the method of their synthesis and use
The subject of the invention is a hybrid photocatalyst which is a layered aluminosilicate, possibly organically modified, containing compounds introduced into the aluminosilicate galleries bearing groups such as porphyrin, rose bengal, anthracene, pyrene, perylene, tetracene, rubrene, naphthalene, phthalocyanines, coumarins, and methylene blue, which are organic chromophores able to absorb visible and/or ultraviolet light and sensitize photochemical reactions. The invention includes also the methods of synthesis and application of the photocatalysts for the photocatalytical degradation of water pollutants.
US08741149B2 Mass spectrometer
A method of chemical separation includes dispensing a sample from a sample pumping system, pumping a solvent from a solvent gradient pumping system to elute the dispensed sample through a separation column, identifying an analyte of interest in the eluting sample, and pumping a solvent from the sample pumping system for peak parking of the analyte in the separation column.