最新美国发明专利第2014-02-18期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

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US08653341B2	Soybean variety A1026458 The invention relates to the soybean variety designated A1026458. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1026458. Also provided by the invention are tissue cultures of the soybean variety A1026458 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1026458 with itself or another soybean variety and plants produced by such methods.
US08653332B2	Extracellular plant ferredoxin-like protein and uses thereof Disclosed are polypeptides, nucleic acids, and related compositions that render plants resistant to bacterial pathogens. Also disclosed are transgenic plants having the nucleic acids and resistant to bacterial pathogens.
US08653331B2	Photobiological hydrogen production with switchable photosystem-II designer algae A process for enhanced photobiological H2 production using transgenic alga. The process includes inducing exogenous genes in a transgenic alga by manipulating selected environmental factors. In one embodiment inducing production of an exogenous gene uncouples H2 production from existing mechanisms that would downregulate H2 production in the absence of the exogenous gene. In other embodiments inducing an exogenous gene triggers a cascade of metabolic changes that increase H2 production. In some embodiments the transgenic alga are rendered non-regenerative by inducing exogenous transgenes for proton channel polypeptides that are targeted to specific algal membranes.
US08653329B2	Cloning and application of a pleiotropic gene Ghd7 that controls grains yield, heading date and plant height of rice The cloning and application of a pleiotropic gene Ghd7 that controls grains yield, heading date and plant height of rice are provided. The gene has the nucleotide sequence as shown in SEQ ID NO: 1. The sequence of the present gene is 3,917 bp in length, contains two exons and encodes 257 amino acids. The cDNA sequence of the gene is as shown in SEQ ID NO: 1. The present gene encodes a protein having the CCT domain of CO protein and having the amino acid sequence as shown in SEQ ID NO: 1. Rice plants transformed with GHD7 gene are obtained using transgenic technology. The transgenic plants all exhibit markedly increased yield, larger number of spikelets per panicle, delayed heading date and elevated plant height as compared to their respective controls (wild type receptors plants). The trait changes are quite consistent with the phenotypes of the two parent genotypes of GHD7 near isogenic lines of Zhenshan 97. The methods for gene cloning, breeding of near isogenic lines and transgene manipulation are also provided, as well as the application of pleiotropic gene GHD7 in research of rice breeding and plant evolution.
US08653320B2	Deodorizing super-absorbent composition The invention relates generally to an odor-absorbing superabsorbing composition, a process for production of an odor-absorbing superabsorbing composition, a composite comprising an odor-absorbing superabsorbing composition, a hygiene article comprising a composite, chemical products comprising or based on an odor-absorbing superabsorbing composition or a composite, as well as the use of an odor-absorbing superabsorbing composition or of a composite in chemical products.
US08653319B2	Cold ionizing radiation sterilization A hydratable gel-forming polymer may be sterilized by chilling the polymer below ambient temperature and sterilizing the chilled polymer using ionizing radiation (e.g., E-Beam radiation). Doing so may reduce the degradation in physical properties caused by ionizing radiation sterilization of the polymer while at ambient temperature, and may preserve or retain desired hydration or gel-forming characteristics.
US08653310B2	Process for making cis-1-chloro-3,3,3-trifluoropropene Disclosed is a process for making cis-1-chloro-3,3,3-trifluoropropene comprising reacting 3,3,3-trifluoropropyne with HCl in a reaction vessel at a yield of at least about 80%.
US08653292B2	Metal organic framework compounds The invention provides novel Zr MOFs, in particular compounds having a surface area of at least 1020 m2/g or if functionalized, having a surface area of at least 500 m2/g.
US08653290B2	Metallocene complex and polymerization catalyst composition containing the same Disclosed are a metallocene complex represented by the general formula (I), (II) or (III), and a polymerization catalyst composition containing such a metallocene complex. In the formulae (I), (II) and (III), M represents a lanthanoid element, scandium or yttrium; CpR independently represents an unsubstituted or substituted indenyl; CpR′ represents an unsubstituted or substituted cyclopentadienyl, indenyl or fluorenyl; Ra-Rf independently represents a hydrogen or an alkyl group having 1-3 carbon atoms; X and X′ respectively represent a hydrogen atom, a halogen atom, an alkoxide group, a thiolate group, an amide group, a silyl group or a hydrocarbon group having 1-20 carbon atoms; L represents a neutral Lewis base; w represents an integer of 0-3; and [B]− represents a non-coordinating anion.
US08653287B2	Decarbonylation process A process is provided for the synthesis of furan and related compounds by liquid-phase decarbonylation of furfural and derivatives, using a palladium/metal aluminate catalyst. The compounds so produced can be used as starting materials for industrial chemicals for use as pharmaceuticals, herbicides, stabilizers, and polymers such as polyether ester elastomers and polyurethane elastomers.
US08653285B2	Aminopropylidene derivative An aminopropylidene derivative having excellent histamine receptor antagonistic action, a compound which is useful as a pharmaceutical composition, especially as an active ingredient, having alleviated side effects in the central nervous system is described. In the aminopropylidene derivative, R1 and R2, which may be identical or different, stand for a hydrogen, a substituted carbonyl, a substituted carbonylalkyl, and acrylic acid, excluding a case where both are hydrogen; R3 and R4, which may be identical or different, stand for hydrogen, an alkyl which may be substituted with phenyl, or the like; A stands for unsubstituted or an oxo; B stands for a carbon or an oxygen; one of X and Y stands for a carbon and the other stands for a sulfur, a broken line part stands for a single bond or a double bond, and a wavy line stands for cis-form and/or trans-form.
US08653282B2	Preparation of dihydrothieno [3,2-D] pyrimidines and intermediates used therein The invention relates to improved methods of preparing dihydrothienopyrimidines of formula 1, and intermediates thereof, (I) wherein X is SO or SO2, preferably SO, and wherein RA, R1, R2, R3, R4 and R5 have the meanings given in the description. The methods according to this invention are more suitable for large-scale synthesis of said compounds than prior methods because the new synthetic process avoids distillation and chromatographic purification between steps and results in a higher overall yield of the desired product.
US08653277B2	Fungicidal composition and method for controlling plant diseases It is to provide a fungicidal composition having stable and high fungicidal effects against cultivated crops infected with plant diseases resulting from plant diseases.A fungicidal composition containing as active ingredients (a) a benzoylpyridine derivative represented by the formula (I) or its salt: (wherein X is a halogen atom, a nitro group, a substitutable hydrocarbon group, a substitutable alkoxy group, a substitutable aryloxy group, a substitutable cycloalkoxy group, a hydroxyl group, a substitutable alkylthio group, a cyano group, a carboxyl group which may be esterified or amidated, or a substitutable amino group, n is 1, 2, 3 or 4; R1 is a substitutable alkyl group, R2′ is a substitutable alkyl group, a substitutable alkoxy group, a substitutable aryloxy group, a substitutable cycloalkoxy group or a hydroxyl group, p is 1, 2 or 3, and R2″ is a substitutable alkoxy group or a hydroxyl group, provided that at least two of R2′ and R2″ may form a condensed ring containing an oxygen atom) and (b) at least one another fungicide.
US08653275B2	Bis-quaternary ammonium cyclophane compounds that interact with neuronal nicotinic acetylcholine receptors Provided are bis-quaternary ammonium cyclophane compounds which are modulators of nicotinic acetylcholine receptors. Also provided are methods of using the compounds for modulating the function of a nicotinic acetylcholine receptor, and for the prevention and/or treatment of central nervous system disorders, substance use and/or abuse, and or gastrointestinal tract disorders.
US08653274B2	Compounds suitable as precursors to compounds that are useful for imaging amyloid deposits The present invention relates to novel derivatives that are suitable as precursors to compounds that are useful for imaging amyloid deposits in living patients, their compositions, methods of use and processes to make such compounds. The compounds deriving from these precursors are useful in methods of imaging amyloid deposits in brain in vivo to allow antemortem diagnosis of Alzheimer's disease by positron emission tomography (PET) as well as measuring clinical efficacy of Alzheimer's disease therapeutic agents. Furthermore, the present invention also discloses the precursor compounds in crystalline form.
US08653273B2	Potent non-urea inhibitors of soluble epoxide hydrolase The present invention relates to compounds that exhibit vasodilatory and anti-inflammatory effects by inhibiting the activity of soluble epoxide hydrolase (sEH). The present invention is also directed to methods of identifying such compounds, and use of such compounds for the treatment of diseases related to dysfunction of vasodilation, inflammation, and/or endothelial cells. In particular non-limiting embodiments, components of the invention may be used to treat hypertension.
US08653271B2	Enhancing transdermal delivery of opioid antagonists and agonists using codrugs linked to bupropion or hydroxybupropion The present invention is directed to novel codrugs comprising bupropion or hydroxybupropion and an opioid antagonist or an opioid agonist joined together by chemical bonding. The codrugs provide a significant increase in the transdermal flux across human skin, as compared to the basic opioid antagonist or opioid agonist.
US08653270B2	Compounds as receptor modulators with therapeutic utility The present invention relates to novel derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
US08653267B2	Co-crystal compound of optical device The present invention discloses a co-crystal compound of optical devices. The co-crystal compound is crystallized out with hydrogen bonding by a temperature fluctuation method after mixing small organic molecules without optoelectronic properties and organic molecules having heterocyclic rings with optoelectronic properties. The photoluminescence (PL) intensity of this hydrogen-bonded co-crystal compound according to the present invention can vary with a variety of the small organic molecules without optoelectronic properties, so as to modulate the PL intensity.
US08653256B2	Method of producing turanose using amylosucrase, and sweetener using the turanose The present invention relates a method of producing turanose using amylosucrase and a sweetener including the turanose. This method enables production of high-purity turanose through an enzymatic reaction occurring by treating a solution including only sucrose or a solution including fructose and sucrose with amylosucrase.
US08653244B2	Anti-epidermal growth factor receptor antibodies and uses thereof The present invention discloses humanized anti-epidermal growth factor receptor antibodies, which have favorable binding activity (the binding affinity being 6.13×10−10 mol/L) and are able to inhibit the growth and migration of tumor cells. The present invention also discloses the preparation methods and uses of the antibodies.
US08653242B2	Therapeutic antibodies against flagellated Pseudomonas aeruginosa Improved antibodies are provided selected from human, dual-specific, chimeric or humanized antibodies, wherein said human chimeric and humanized antibodies specifically bind to flagellin type A or type B of P. aeruginosa, and said dual-specific antibodies specifically binds to flagella type A and type B of Pseudomonas aeruginosa, and said antibodies are protective against infection caused by P. aeruginosa. These antibodies as well as pharmaceutical composition comprising them are useful for the treatment of indications caused by P. aeruginosa infection.
US08653241B2	Phospholipase polypeptide and a DNA encoding same The invention relates to a DNA sequence that encodes a polypeptide with phospholipase activity and was isolated from Aspergillus and sequences derived therefrom, polypeptides with phospholipase activity encoded by these sequences as well as the use of these polypeptides for degumming of vegetable oil, for the preparation of dough and/or bakery products, for the preparation of dairy products, for processing steps in the textile industry and for related applications.
US08653234B2	Peptide vaccines for cancers expressing MPHOSPH1 or DEPDC1 polypeptides The present invention provides peptides having an amino acid sequence as set forth in SEQ ID NO: 7, 8, 9, 10, 11, 12, 192, 195, 197, 209, 225, 226, 228, 230, 240, 241, 243, 244, 249, 253, 254 or 255, as well as peptides having the above-mentioned amino acid sequences in which 1, 2, or several amino acids are substituted, deleted, or added, wherein the peptides possess cytotoxic T cell inducibility. The present invention also provides drugs for treating or preventing a disease associated with the over-expression of MPHOSPH1 and/or DEPDC1, e.g. cancers, containing these peptides as an active ingredient. The peptides of the present invention can also be used as vaccines.
US08653231B2	Synthesis of conducting polymer nanofibers using an oligomer of a monomer as an initiator The present invention involves synthesizing conducting polymer nanofibers by mixing an oxidant solution with a monomer solution, which includes a monomer and an oligomer of the monomer that is used as an initiator. The oxidant solution includes an oxidizing agent, or oxidant, such as ferric chloride to oxidize the monomer, the oligomer, or both, and begin polymerization. By including an initiator in the form of the oligomer, which may have a lower oxidation potential than the monomer, the rate of polymerization is accelerated, resulting in the nanofibrous morphology. Therefore, the conducting polymer nanofibers may be synthesized without the use of surfactants, hard templates, or seeds, resulting in a simplified and accelerated polymerization process, which enhances homogenous nucleation of the conducting polymer nanofibers.
US08653230B2	Monomers, oligomeric complexes, coordination polymers, and methods for their preparation and use Implementations and techniques for preparing and using monomers, oligomeric complexes, and coordination polymers are generally disclosed.
US08653229B2	Polymerisation of hexafluoropropylene oxide Process for the oligomerization of hexafluoropropylene oxide (HFPO) in which the sum of the dimers, trimers, tetramers, pentamers and hexamers represents less than 20% of the weight of the polymerized HFPO, the oligomers other than the dimers, trimers, tetramers, pentamers and hexamers (the remaining oligomers) having an average molecular weight ranging between 1100 and 4000 g/mol, characterized in that the process comprises the steps of contacting hexafluoropropylene oxide (HFPO) at a temperature between −30° C. to +50° C. with a catalyst system selected from potassium fluoride and di-, tri- or tetraethyleneglycol-dimethylether in the presence of a solvent which is selected from perfluorinated aliphatic or aromatic hydrocarbon with more than 3 and less than 12 C-atoms and optionally a polar group but not comprising chlorine or bromine partially fluorinated aliphatic or aromatic hydrocarbon with more than 3 and less than 12 C-atoms and optionally a polar group but not comprising chlorine or bromine at a pressure of less than 3 bars by controlled monomer addition continuous feeding or by adding the monomer in one or two portions (shots).
US08653226B2	Polyesteracetals A polyesteracetal contains —[C(O)(CR3R4)x(C(O))yOCR1R2O]— repeating unit where x is 0 to 5, y is 0 or 1, and R1, R2, R3 and R4 are independently H, C1 to C24 alkyl, C2 to C24 alkenyl, C6 to C14 aryl, C7 to C24 alkylaryl, heteroatom interrupted C1 to C24 alkyl, heteroatom interrupted C2 to C24 alkenyl, heteroatom interrupted C4 to C14 aryl, or heteroatom interrupted C5 to C24 alkylaryl, and wherein on average x>1 or y>0. The polyesteracetal can be a homopolymer or copolymer. A method of preparing the polyesteracetal comprises a ring-opening polymerization of a cyclic esteracetal monomer using a metal alkolate, metal alkoxide or metal alkyl initiator.
US08653225B2	Polyamide compound A polyamide compound containing from 25 to 50 mol % of a diamine unit that contains at least 50 mol % of an alicyclic diamine unit represented by the following general formula (I); from 25 to 50 mol % of a dicarboxylic acid unit that contains a linear aliphatic dicarboxylic acid unit represented by the following general formula (II-1) and/or an aromatic dicarboxylic acid unit represented by the following general formula (II-2) in an amount of at least 50 mol % in total; and from 0.1 to 50 mol % of a constituent unit represented by the following general formula (III): wherein, in the formulae, n indicates an integer of from 2 to 18; Ar represents an arylene group; and R represents a substituted or unsubstituted alkyl group, or a substituted or unsubstituted aryl group.
US08653218B2	Synthesis and characterization of amine terminated cycloaliphatic substituted polysiloxanes The present invention relates to novel amine terminated cycloaliphatic polysiloxanes, and preparations thereof. More particularly, the invention provides several reaction schemes for the synthesis of amino-functionalized cyclo-aliphatic silicones and the products produced by the reaction schemes. In one embodiment of the invention, an amine functionalized silicone is prepared through a base-catalyzed ring-opening reaction. In another embodiment of the invention, an amine functionalized silicone is prepared through the hydrosilation of a silicone oligomer through the blocking and deblocking of an amine terminated in a vinyl group.
US08653215B2	Process for producing water-absorbing polymer particles A process for producing water-absorbing polymer particles by polymerizing an aqueous monomer solution in a kneader having at least two shafts in axially parallel rotation, wherein the reaction mixture is transported in axial direction and the region at the start of the kneader is trace-heated.
US08653212B2	Low melt flow branched ionomers Embodiments of the present invention include a branched aromatic ionomer, and a process of making it, by co-polymerizing a first monomer comprising an aromatic moiety and an unsaturated alkyl moiety and a second monomer represented by the general formula: [R-AZ]y-MX wherein R is a hydrocarbon chain having from 2 to 40 carbons and at least one polymerizable unsaturation; A is an anionic group; M is a cationic group; Z is −1 or −2; X is +1, +2, +3, +4, or +5; and y is an integer having a value of from 1 to 4. The branched aromatic ionomer has a melt flow index ranging from 1.0 g/10 min. to 13 g/10 min. Optionally the melt flow index ranges from 1.3 g/10 min. to 1.9 g/10 min.
US08653210B2	Continuous process for the production of a superabsorbent polymer The present invention relates to a continuous process for the production of a superabsorbent polymer comprising providing an acidic liquid aqueous monomer mixture containing dissolved oxygen; continuously feeding the aqueous monomer mixture to a reactor; introducing a source of carbonate or hydrogen carbonate into the aqueous monomer mixture prior to entry into the reactor thereby forming a gas phase comprising carbon dioxide and at least a part of the dissolved oxygen, the gas phase being dispersed in the liquid phase; subjecting the gas/liquid mixture to at least partial phase separation immediately prior to or after entry into the reactor and at least partially removing the separated gaseous phase; subjecting the liquid phase in the reactor to free-radical polymerization to obtain the superabsorbent polymer, and continuously removing the superabsorbent polymer from the reactor.
US08653197B2	Thermoplastic vulcanizate composition The disclosure is directed to a thermoplastic vulcanizate composition comprising a dynamically-cured rubber; from about 20 to about 300 parts by weight of a thermoplastic resin per 100 parts by weight rubber and from about 30 to about 250 parts by weight additional oil per 100 parts by weight rubber; wherein the rubber comprises a multimodal polymer composition cured with a curing agent, the multimodal polymer composition comprising 45 to 75 wt % of a first polymer fraction and 25 to 55 wt % of a second polymer fraction, each comprising ethylene, a C3-C10 alpha-olefin, and a non-conjugated diene. A method of producing the thermoplastic vulcanizate is also disclosed.
US08653195B2	Hydrocarbon polymer modifiers for elastomeric compositions An elastomeric composition incorporating a hydrocarbon polymer modifier including piperylene, cyclic pentadiene and aromatic components, and having a softening point from 80° C. to 160° C., z-average molecular weight greater than 10,000, and at least 1 mole percent aromatic hydrogen, based on the total moles of hydrogen in the modifier. In a method, the elastomeric composition is processed with a cure package into a composition in the desired shape, which is cured to form the article. The modifier may optionally be immiscible with an elastomer in the composition and/or co-cured with the elastomer or filler in the composition. A tire or tire component may include the elastomeric composition.
US08653193B2	Polyolefin compositions and products made therefrom A polymeric composition that is suitable for use as a film or a coating. The polymeric composition comprises: (a) a first component comprising copolymer derived from ethylene and one or more C3 to C20 α-olefin comonomers. The first component has a density of about 0.911 to about 0.918 g/cm3, a compositional distribution breadth index (CDBI) of about 60% to about 85%, a melt index (MI) of about 16.0 to about 30.0 g/10 min, a molecular weight distribution (MWD) of about 1.5 to about 4.0, and a melt index ratio (MIR) of less than about 25; and (b) a second component comprising a low density polyethylene (LDPE). The second component has a g′ of about 0.8 to about 0.15 and a MI that is lower than the MI of the first component.
US08653192B2	Method for manufacturing a polyester composition having improved impact properties A method for manufacturing a thermoplastic composition including: a polyester resin (c); a mixture including a copolymer (a) of an α-olefin and of a monomer having an ethylenic unsaturation and an epoxy function, as well as a core-shell compound (b); characterized in that said method includes a first step of manufacture the mixture of (a) and (b) by extrusion at a temperature at which the copolymer (a) is in the molten state and at a maximum temperature of 60 to 180° C.; a second step of manufacturing the thermoplastic composition by extrusion or by mixing the polyester resin (c) with the mixture of (a) and (b) produced in the first step.
US08653188B2	Thermoplastic resin composition and resin molded product The object of the present invention is to provide a thermoplastic polymer composition which is excellent in the impact resistance, a fracture morphology and rigidity, as well as has a possibility of the effect for reducing environmental load.The thermoplastic resin composition comprises 15 to 85% by mass of aliphatic polyester-based resin (A) comprising the following (AI) and (AII) components, and 15 to 85% by mass of styrene-based resin (B) which is at least one selected from the group consisting of the following (BI) to (BIII). The above (AI) is an aliphatic polyester-based resin having units formed from an aliphatic diol and/or an alicyclic diol and an aliphatic dicarboxylic acid (including derivatives thereof) and/or an alicyclic dicarboxylic (including derivatives thereof) as repeating units, and the above (AII) is a polylactic acid-based aliphatic polyester resin having not less than 70 mol % of lactic acid unit content.The above (BI) is a graft copolymer obtained by polymerizing vinyl-based monomers (b2) comprising an aromatic vinyl compound and another vinyl compound copolymerizable therewith in the presence of rubber polymer (b1), the above (BII) is a polymer of vinyl-based monomers (b2), and the above (BIII) is a mixture of said (BI) and (BII).
US08653187B2	Use of nano alumina or silica dispersed in polystyrene Disclosed is a method of making a polystyrene based nanocomposite by combining a monomer with a nanoparticle to form a mixture and subjecting the mixture to polymerization conditions to produce a polymeric composite. In an embodiment the nanoparticle has been treated with an additive prior to combining with the monomer and the additive contains a silane moiety.
US08653186B2	Plasticizer-containing hardening accelerator composition The invention concerns a process for the preparation of a hardening accelerator composition by reaction of a water-soluble calcium compound with a water-soluble silicate compound and a process for the preparation of a hardening accelerator composition by reaction of a calcium compound with a silicon dioxide containing component under alkaline conditions, in both cases the reaction of the water-soluble calcium compound with the water-soluble silicate compound being carried out in the presence of an aqueous solution which contains a water-soluble comb polymer suitable as a plasticizer for hydraulic binders. The invention concerns also a composition of calcium silicate hydrate and comb polymer, its use as hardening accelerator and for the reduction of the permeability of hardened compositions.
US08653183B2	Method of curing a coating composition comprising a radical curable compound and an organoborane-amine complex A method of curing a coating composition and a method of forming a cured coating on an automobile component are provided. The coating composition comprises a radical polymerizable compound and an organoborane-amine complex having an organoborane initiator, an amine blocking agent, and water. The method of curing the coating composition comprises the steps of combining the organoborane-amine complex, the radical polymerizable compound, and water to form the coating composition. Carbon dioxide is introduced into the coating composition or into a composition including at least one of the organoborane-amine complex, the radical polymerizable compound, and water prior to forming the coating composition. Carbonic acid is formed in situ within the coating composition through reaction of the water and carbon dioxide. The organoborane-amine complex is decomplexed with the carbonic acid thereby separating the organoborane initiator and the amine blocking agent. The radical polymerizable compound is polymerized using the organoborane initiator in the presence of oxygen.
US08653180B2	Aqueous compositions comprising a blend of emulsion vinyl copolymer and polyurethane dispersion The present invention provides compositions that enable excellent early hardness development in coating applications, the compositions comprising a blend of one or more copolymer, pA, having a Tg of 20° C. or higher, and one or more polyurethane copolymer in aqueous dispersion, pB, together with one or more additive chosen from a coalescent having a normal boiling point of from 150° C. to no greater than 300° C., a naturally derived plasticizer, and mixtures thereof. The polyurethane copolymer comprises at least 40 wt. %, based on the weight of polyurethane solids, of: (i) a first polyol having a molecular weight of at least 850, wherein the first polyol is a polyether polyol, or (ii) a second polyol chosen from a polyester, a polycaprolactam, a polycarbonate and a combination thereof, wherein the second polyol has a molecular weight of at least 1,500, or (iii) a combination of one or more first polyol and one or more second polyol. The compositions may be ambient curable.
US08653179B2	Polycarbonate resin composition with good light stability and dimensional stability The present invention relates to a polycarbonate resin composition that can have excellent light stability and dimensional stability, including: (A) 70 to 95 parts by weight of a thermoplastic polycarbonate resin; (B) 5 to 40 parts by weight of a thermoplastic non-crystalline polyester copolymer; (C) 5 to 50 parts by weight of titanium dioxide; (D) 0.1 to 10 parts by weight of an organic siloxane copolymer; and (E) 0.05 to 5 parts by weight of a fluorinated polyolefin-based resin. The polycarbonate resin composition can have excellent light stability and dimensional stability and also can have excellent mechanical strength without reduced impact strength and workability. The polycarbonate resin composition can be used in molded products such as LCD backlight parts requiring product dimensional stability and other parts requiring light stability.
US08653178B2	High wear-resistant nylon composite material for rollers on airport freight vehicles and preparation method thereof A high wear-resistant nylon composite material for rollers of an airport freight vehicle and a preparation method thereof are disclosed. The composite material includes the following materials as the main components, 60-80 wt % of nylon 6 or nylon 66 or a mixture of nylon 6 and nylon 66, 5-13 wt % of glass beads, 6-14 wt % of glass fiber powder, 5-7 wt % of lubricating anti-wear agent. The composite material further includes the following materials as the auxiliary materials, 3-5 wt % of graft type toughening modifying agent, 0.3-1 wt % of antioxidant, 0.2-0.3 wt % of lubricating dispersant and 0.2-0.5 wt % of nucleating agent. The composite has characteristics such as high wear resistance, high heat resistance, relatively high toughness and skid resistance.
US08653177B2	Semiconductive resin composition The invention relates to a semiconductive resin composition containing at least two kinds of conductive fillers, wherein the difference in threshold values of percolation between at least two kinds of the conductive fillers is within a range of 10 to 50 mass %. The semiconductive resin composition of the present invention can be used widely in various form of molded products, such as component used for transport in a clean room, spin chuck, IC test socket, various rollers installed in copier, seamless belt, bearing, antistatic fiber, member for electrostatic coating, fuel tube, part around fuel or chemical tube.
US08653176B2	Thermally conductive material and thermally conductive sheet molded from the thermally conductive material Disclosed is a thermally conductive material having excellent heat conductivity and insulating properties and having flame retardancy while retaining flexibility and toughness. More specifically, there is provided a thermally conductive material comprising: a hydrogenated copolymer (1) and/or a modified hydrogenated copolymer (2) in which each has a specific structure and is contained in a specific amount; and zinc oxide (3) comprising a core part and acicular crystal parts extending from the core part in four axial directions. The thermally conductive material optionally further comprises a paraffin oil (4), a flame retardant (5), or a filler (6) having a thermal conductivity of 10 to 400 W/m·K (the zinc oxide (3) is excluded).
US08653173B2	Elastic member for ink jet Provided is an elastic member for ink jet, including a styrene-based thermoplastic elastomer and a thermoplastic resin, in which the elastic member further includes at least a nonionic surfactant having an ethylene oxide adduct, and the content of the nonionic surfactant is 0.1 to 5 mass % with respect to the styrene-based thermoplastic elastomer. The elastic member has sufficient releasability and high liquid-contact properties, which suppresses clogging of ejection orifices due to precipitation when eluted in ink.
US08653172B2	Plasticiser blends and compositions and articles made therefrom Plasticizer blends of C10 to C14 dialkyl phthalates or C8 to C10 trimellitates and C11 to C14 dialkyl adipates are provided. The blends may be used in the manufacture of flexible PVC formulations, for example, as wire and cable coatings, having in several embodiments, good performance over a wide temperature range and are particularly useful for automotive cables.
US08653164B2	Inorganic board and manufacturing method thereof An inorganic board is formed of an aluminosilicate setting material, a wooden reinforcing material and an aggregating agent. The wooden reinforcing material is covered by the aggregating agent, and this agent is covered by the aluminosilicate setting material. A method of manufacturing the inorganic board has the steps of covering a wooden reinforcing material with an aggregating agent; producing a starting material mixture by mixing the thus-obtained wooden reinforcing material with an aluminosilicate powder, an alkali metal hydroxide and water glass; and molding and curing the thus-obtained starting material mixture.
US08653159B2	Apparatus for heat-treating toner and method for producing toner An apparatus for heat-treating a toner includes a raw-material supply unit configured to supply a toner treatment space with a raw-material toner, a hot-air supply unit configured to heat-treat the raw-material toner in the toner treatment space, a suction and ejection unit configured to eject hot air used for the heat treatment of the raw-material toner, and a waste-heat recovery and supply unit configured to recover heat from the hot air ejected by the suction and ejection unit and supply the hot-air supply unit with the recovered heat.
US08653156B2	Composite material having the appearance of natural stone Disclosed is a composite material having the appearance of natural stone that made from a polymer and natural aggregate. The composite material also has an antimicrobial material incorporated into it that resists the proliferation of microbes on the surface of the material. A method for producing this material is also disclosed.
US08653154B2	Synergistic effects of blending multiple additives in UHMWPE Oxidation resistant crosslinked ultrahigh molecular weight polyethylene (UHMWPE) is described, wherein at least two different additives in the manufacture synergistically increase the oxidation resistance of crosslinked UHMWPE. This allows the manufacture of oxidation resistant crosslinked UHMWPE using lower levels of additives and/or lower levels of crosslinking irradiation or chemicals. The lower levels of additives and/or crosslinking produce crosslinked UHMWPE having desired physical properties not possible without the synergistic interaction of the additives. This crosslinked UHMWPE may be used in medical prostheses such as in bearing components having desired physical properties such as wear resistance and oxidation resistance not possible without the synergistic interaction of the additives.
US08653153B1	Violet curable ink A violet radiation curable ink including at least one curable monomer, at least one organic gellant, at least one photoinitiator, and at least one colorant, wherein the ink exhibits a reflectance on a substrate at a loading of from about 2 mg/inch2 to about 7 mg/inch2 that ranges from 50% to about 60% at a wavelength of 500 nm and that ranges from 0% to about 10% at a wavelength of about 600 nm. Also, the violet ink substantially matches PANTONE® Violet.
US08653152B2	Porous resin bead and method for producing nucleic acid using the same The present invention relates to a porous resin bead containing a first aromatic monovinyl compound-divinyl compound-(meth)acrylonitrile-second aromatic monovinyl compound copolymer, in which the second aromatic monovinyl compound contains a group capable of binding with a carboxyl group by dehydration condensation reaction, and in which the porous resin bead has a dry volume of from 2 to 3 ml/g.
US08653151B2	Articles prepared using recycled materials and methods of preparation thereof The present invention is directed to articles of manufacture having at least a portion prepared using recycled material, including but not limited recycled rubber or other polymeric materials. The articles may incorporate the recycled materials in a granulated form. In specific embodiments, the article comprises an article of footwear (i.e., a shoe). Particularly, all or part of the shoe sole may be formed using the granulated material, the granules specifically being joined together using a binder material, such as a polyurethane, preferably a moisture cure, single component polyurethane binder. The invention further provides methods of preparing articles formed of granulated materials. The inventive methods are characterized by their excellent economic benefits, ease of use, and environmental benefits.
US08653150B2	Method for decomposing thermoset resin and recovering decomposition product The present invention relates to a method for decomposing, in the presence of subcritical water, a thermosetting resin comprising a polyester moiety and a crosslinking moiety therewith to provide a compound comprising an acid residue derived from the polyester moiety and a residue derived from the crosslinking moiety, and collecting the compound in an efficient yield, specifically, which comprises steps of: (I) decomposing the thermosetting resin in the presence of subcritical water to provide a solid comprising a compound comprising an acid residue derived from the polyester moiety and a residue derived from the crosslinking moiety, (II) subjecting the solid to an organic solvent to dissolve the compound into the organic solvent, wherein the organic solvent has a higher solubility which can dissolve the compound than that of water, and (III) collecting, separating or isolating the compound from the organic solvent.
US08653149B2	Conversion of liquid heavy hydrocarbon feedstocks to gaseous products The present invention relates to processes and apparatuses for generating light olefins, methane and other higher-value gaseous hydrocarbons from “liquid” heavy hydrocarbon feedstocks.
US08653148B2	Microwave process and apparatus for breaking emulsions A oil and water emulsion breaking system having a reactor including an inner vessel connected to an inlet and an outlet of the reactor and allowing microwaves to pass therethrough, a packed bed of activated carbon retained within and across the inner vessel along at least part of a length thereof and configured for circulation of the emulsion therethrough, and a microwave applicator configured to direct microwaves to the packed bed through the inner vessel.
US08653140B2	Administration of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid for the treatment of dermatological disorders Dermatological disorders having an inflammatory or proliferative component are treated with pharmaceutical compositions containing on the order of 0.3% by weight of 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid (adapalene) or salt thereof, formulated into pharmaceutically acceptable media therefor, advantageously topically applicable gels, creams or lotions.
US08653138B2	Calcium salts of compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents The present invention relates to calcium salts of compounds of the general formula (I) wherein X is selected from the group consisting of CH2, S, or O; D is O or S; R8 is hydrogen or alkyl; E is an optionally substituted phenylene group; Y is a monocyclic or bicyclic substituted or unsubstituted 6-9 membered ring system which may contain one or more heteroatoms selected from N or S and which contains at least one aromatic ring; n is 0 or 1, and q is 0 or 1; with the proviso that compounds wherein X═CH2, q=0, Y=unsubstituted phenyl and E=unsubstituted phenylene are excluded; or a hydrate thereof.
US08653136B2	Compositions based on amino acids for improving the myocardial ventricular function in patients suffering from diabetes Compositions based on amino acids are described, for improving the myocardial ventricular function in patients suffering from diabetes, particularly but not exclusively II type diabetes. The compositions according to the invention comprise up to 75% of the branched chain amino acids leucine, isoleucine and valine, as active ingredients. Preferably, the compositions also comprise, as further active ingredients, up to 50% of threonine and lysine. Other essential amino acids are preferably also provided, in particular methionine, phenylalanine, histidine, tryphtophan, as well as non essential amino acids, in particular tyrosine and/or cyst(e)ine (i.e., cystine and cysteine). Other amino acids can be added, provided that their sum is in a percentage being lower than 20% with respect to the other active ingredients, and less than 10% for each single amino acid.
US08653135B1	Alternating sympathomimetic therapy for the treatment of respiratory aliments A combination of dosage units for alleviating respiratory ailments and a method of alleviating respiratory ailments which uses this combination of dosage units. The dosage units comprise one or more first dosage units comprising pseudoephedrine and/or a pharmaceutically acceptable salt thereof and one or more second dosage units comprising phenylephrine and/or a pharmaceutically acceptable salt thereof. This Abstract is neither intended to define the invention disclosed in this specification nor intended to limit the scope of the invention in any way.
US08653134B2	Hydroxyphenol derivatives, processes for the preparation thereof, pharmaceutical compositions them, and therapeutic uses thereof Compounds of the formula (I): in which A, R1, R2, X, Y and Z are defined in the description, the processes for the preparation of these compounds, the uses thereof for the treatment of dyslipidaemia, atherosclerosis and diabetes, and the pharmaceutical compositions comprising them.
US08653132B2	Phosphaplatins and their use in pharmaceutical compositions The present invention provides pharmaceutical compositions comprising phosphaplatins, stable isolated monomeric phosphato complexes of platinum (II) and (IV). In some embodiments, such compositions may be useful for treating cancers, including cisplatin- and carboplatin-resistant cancers. The provided phosphaplatin complexes do not readily undergo hydrolysis and are quite soluble and stable in aqueous solutions. Moreover, these complexes—unlike cisplatin, carboplatin, and related platinum-based agents—do not bind DNA. Rather, data suggests that phosphaplatins trigger overexpression of fas and fas-related transcription factors and some proapoptotic genes such as Bak and Bax. Nevertheless, the complexes exhibit tremendous cytotoxicity towards cancer cells. Thus, the present invention provides novel platinum agents that have a different molecular target than those in the art.
US08653125B2	Cyclohexane derivative having NPY Y5 receptor antagonism The present invention discloses novel cyclohexane derivatives having NPY Y5 receptor antagonistic activity. Specifically, the present invention discloses a compound represented by the formula (I), or a pharmaceutically acceptable salt or a solvate thereof: wherein A is substituted or unsubstituted aryl or heterocyclyl; a combination of X and Y is a combination selected from (X, Y)═(C(═O)N(R1), C(═O)N(R2)), (C(═O)N(R1), imidazole-1,3-diyl), (N(R1), C(═O)N(R2)), (O, C(═O)N(R2)), (C(R3)(R4), N(R2)) or (a single bond, C(═O)N(R2)); R1, R2 and R3 are independently hydrogen or substituted or unsubstituted alkyl; R5 is substituted or unsubstituted aryl or heterocyclyl; R6 is halogen, oxo, substituted or unsubstituted alkyl, substituted or unsubstituted alkoxy, substituted or unsubstituted aryloxy; m is 0 or 1; and n is an integer of 0 to 5; and B is aromatic carbocycle, monocyclic heterocycle or fused bicyclic heterocycle.
US08653124B2	Inhibition of bacterial biofilms with imidazole derivatives Disclosure is provided for imidazole derivative compounds that prevent, remove and/or inhibit the formation of biofilms, compositions comprising these compounds, devices comprising these compounds, and methods of using the same.
US08653116B2	Isoxazoline derivatives as pesticides The invention relates to new isoxazoline compounds of formula wherein the variables have the meaning as indicated in the claims; in free form and in salt form; and optionally the enantiomers and geometrical isomers thereof. The compounds of formula (I) are useful in the control of parasites, in particular ectoparasites, in and on warm-blooded animals.
US08653115B2	Heterocyclic non-nucleoside compounds, their preparation, pharmaceutical composition and their use as antiviral agents The invention relates a kind of antiviral agents, more concretely, relates to a kind of heterocyclic non-nucleoside compounds with the following structures, their preparation and pharmaceutical compositions including the compounds. The said compounds can be used as antiviral agents and as medicaments for treating diseases such as hepatitis B, influenza, herpes, HIV and so on.
US08653111B2	Substituted dihydropyrazolones for treating cardiovascular and hematological diseases The present application relates to novel substituted dihydropyrazolone derivatives, processes for their preparation, their use for treatment and/or prophylaxis of diseases and their use for the preparation of medicaments for treatment and/or prophylaxis of diseases, in particular cardiovascular and hematological diseases and kidney diseases, and for promoting wound healing.
US08653110B2	Active compound combination comprising azadirachtin and a substituted enaminocarbonyl compound Disclosed are novel active compound combinations comprising at least one substituted enaminocarbonyl compound and azadirachtin, which combinations are highly suitable for controlling animal pests such as insects and unwanted acarids. Methods of controlling insects and acarids are also disclosed.
US08653109B2	Substituted bipyridine derivatives and their use as adenosine receptor ligands The present invention relates to novel substituted 2,4′- and 3,4′-bipyridine derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of hypertension and other cardiovascular disorders.
US08653107B2	Fentanyl composition for nasal administration The treatment of acute pain with a sufficient dosage by intranasal administration of fentanyl results in a time to onset of action comparable to intravenous administration and a significantly faster onset of action than nasal titration of fentanyl. The nasal administration of a sufficient amount of fentanyl to obtain pain relief has lower maximum plasma concentrations comparable to intravenous administration and results in lower rates of adverse events like respiratory depression, nausea and vomiting. Compositions for use in the method are also disclosed.
US08653105B2	Quinoline derivatives as kinase inhibitors A series of quinoline derivatives, substituted by an optionally substituted bicyclic heteroaryl moiety consisting of two fused six-membered aromatic rings attached via an alkylene chain optionally linked to a heteroatom, being selective inhibitors of PI3 kinase enzymes, are accordingly of benefit in medicine, for example in the treatment of inflammatory, autoimmune, cardiovascular, neurodegenerative, metabolic, oncological, nociceptive or ophthalmic conditions.
US08653103B2	Solid forms of 3-(6-(1-(2,2-difluorobenzo[D][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid The present invention relates to a substantially crystalline and free solid state form of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Form I), pharmaceutical compositions thereof, and methods of treatment therewith.
US08653100B2	Tetrahydroisoquinolines, pharmaceutical compositions containing them, and their use in therapy The present invention relates to tetrahydroisoquinoline of the formula (I) or a physiologically tolerated salt thereof. The invention relates to pharmaceutical compositions comprising such tetrahydroisoquinolines, and the use of such tetrahydroisoquinolines for therapeutic purposes. The tetrahydroisoquinolines are GlyT1 inhibitors.
US08653095B2	Small molecules with antimalarial activity The present invention provides new chemical compositions with desirable biological activity and toxicity profiles for the enhanced treatment of malaria.
US08653094B2	Solid forms of (S)-ethyl 2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)-pyrimidin-4-yl)phenyl)propanoate and methods of their use Solid forms of (S)-ethyl 2-amino-3-(4-(2-amino-6-((R)-1-(4-chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl)-2,2,2-trifluoroethoxy)pyrimidin-4-yl)phenyl)propanoate and salts thereof are disclosed.
US08653090B2	Compositions and methods for treatment of the side-effects associated with administration of cancer chemotherapeutic agents A composition and method for the treatment of the side-effects associated with the administration of cancer chemotherapeutic agents involves the oral ingestion of a slow release capsule containing adenine and orotate. The administration of a protein pump inhibitor decreases systemic absorption of orotate and the administration of allopurinol decreases the formation of 2,8-dihydroxy adenine from adenine. In an alternative embodiment, cationic liposomes contain purine/pyrimidine precursors. The cationic liposomes bind to the cells lining the mucosa of the intestinal tract and then the contents of the cationic liposome are then taken up in the interior of the cells to prevent the metabolism of the cancer treatment drug 5-FU into a toxic species.
US08653086B2	Naphthamides as anticancer agents A compound (particularly useful for inhibiting cancer) according to formula I: or a pharmaceutically acceptable salt thereof, wherein: x is 0 or 1; R1-R6 are each independently H, —CN, —NO2, —NO, —OH, halogen, hydroxyalkyl, carboxyl, substituted carboxyl, aminocarbonyl, alkoxy, carbonyl or substituted carbonyl; R7 is H, alkyl, alkyl amino, aminoacyl, hydroxyacyl, heteroaryl, heterocycloalkyl, alkyl heteroaryl or alkyl heterocycloalkyl; R8 is H or alkyl; A is O or N; and Ar is an aryl, substituted aryl, heteroaryl, or substituted heteroaryl, provided that if R7 is H then Ar is aryl substituted with alkyl amino.
US08653084B2	Hydrobenzamide derivatives as inhibitors of Hsp90 The invention provides an acid addition salt of a compound of the formula (1) Also provided by the invention are processes for preparing the compound of formula (1) and alkyl analogues thereof, novel intermediates for use in the process and methods for preparing the intermediates. The invention also provides new medical uses of compounds of the formula (1) and its ethyl analogue.
US08653083B2	Hedgehog pathway antagonists to treat disease Compounds, compositions, kits and methods for modulating hedgehog pathway activity, and treating conditions related to abnormal or aberrant hedgehog pathway activity, are disclosed.
US08653080B2	Methods for screening and compounds that protect against amyloid diseases The disclosure provides methods and compositions useful for screening inhibitors of aggregation mediated proteotoxicity. The disclosure provides transgenic animals and cell useful for such screening. Also provided are compounds useful for inhibiting aggregation mediated proteotoxicity in a subject.
US08653078B2	Herbicidal pyrido[2,3-b]pyrazines The present invention relates to a method of controlling plants or inhibiting plant growth which comprises applying to the plants or to the locus thereof a herbicidally effective amount of a compound of formula (I) wherein R1, R2, R3, R4 and R5 are as defined in claim 1; or a salt or N-oxide thereof. Furthermore, the present invention relates to processes for preparing compounds of formula (I), to intermediates used in the preparation of compounds of formula (I), to herbicidal compositions comprising compounds of formula (I) and to certain novel pyridopyridines.
US08653076B2	Oxo-substituted imidazo[1,2B]pyridazines, their preparation and use as pharmaceuticals The invention relates to novel inhibitors of kinases of the general formula (I): in which Q and R1 are defined in the claims, method for preparing such inhibitors, intermediates for preparing such inhibitors and uses of such inhibitors.
US08653073B2	Dihydroindolone compounds, a process for their preparation and pharmaceutical compositions containing them Compounds of formula (I): wherein: m and n represent 1 or 2, A represents a pyrrolyl group, X represents a C(O), S(O) or SO2 group, R1 and R2 represent an alkyl group or, together with the nitrogen atom carrying them, form a heterocyclic group, R3 and R4, together with the atoms carrying them, form a heterocyclic group, R5 represents a hydrogen atom or an alkyl group, R6 represents a hydrogen atom or a halogen atom. Medicinal products containing the same which are useful in treating cancer.
US08653071B2	α4β2 neuronal nicotinic acetylcholine receptor ligands The present invention relates to novel α4β2 neuronal nicotinic acetylcholine receptor ligand compounds of the formula (I), and their derivatives, stereoisomers, pharmaceutically acceptable salts and compositions containing them. The present invention relates to novel α4β2 neuronal nicotinic acetylcholine receptor ligand compounds of the formula (I), and their derivatives, stereoisomers, pharmaceutically acceptable salts and compositions containing them.
US08653070B2	Hepatitis C virus inhibitors The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, esters, or prodrugs thereof: which inhibit RNA-containing virus, particularly the hepatitis C virus (HCV). Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
US08653068B2	Filamin A binding anti-inflammatory and analgesic A compound or its pharmaceutically acceptable salt, composition and method are disclosed that can provide analgesia and reduce inflammation. A contemplated compound has a structure that corresponds to Formula A, wherein the R group substituents, d, e, f, k, n, m, D, E, F, K, G, P, Q, W, and Z are defined within.
US08653067B2	Pharmaceutical composition for treating Alzheimer's disease A pharmaceutical composition for treating Alzheimer's disease containing a compound represented by the general formula (I); wherein ring A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group; E is lower alkylene, etc.; X is S, O, or NR1; R1 is a hydrogen atom or lower alkyl; R2a, R2b, R3a, R3b, R4a and R4b are each independently a hydrogen atom, halogen, hydroxy, etc.; n and m are each independently an integer of 0 to 3; n+m is an integer of 1 to 3; and R5 is a hydrogen atom, optionally substituted lower alkyl, etc.; its pharmaceutically acceptable salt, or a solvate thereof as an active ingredient.
US08653063B2	N-substituted saturated heterocyclic sulfone compounds with CB2 receptor agonistic activity This invention relates to compounds of formula (I) or a pharmaceutically acceptable salt thereof, wherein X, R1, R2, R3, R4, R5, R6, R7, k, m, n, p, q, r and s are each as described herein, and compositions containing such compounds, and the use of such compounds in the treatment of a condition mediated by CB2 receptor activity.
US08653062B2	Compounds as receptor modulators with therapeutic utility The present invention relates to novel cyclic amine and cycloalkyl derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of sphingosine-1-phosphate receptors.
US08653060B2	Formulations of 6-mercaptopurine The present invention provides improved formulations of 6-mercaptopurine that exhibit better bioavailability and faster dissolution than previous formulations.
US08653058B2	Compositions comprising deoxycholic acid and salts thereof suitable for use in treating fat deposits The present application is directed to an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid, wherein the composition is maintained at a pH from about 8.1 to about 8.5 such that the composition is stabilized against precipitation. Also disclosed herein, are methods for stabilizing an aqueous pharmaceutical composition comprising from about 0.4% w/v to less than about 2% w/v of a salt of deoxycholic acid against precipitation, said method comprising maintaining pH of the solution from about 8.1 to about 8.5.
US08653056B2	Method of preparation of a soluble formulation of water-insoluble pentacyclic and tetracyclic terpenoids, a soluble formulation of a pentacyclic or tetracyclic terpenoid and a pharmaceutical composition containing this soluble formulation The invention relates to a method of preparation of a soluble formulation of water-insoluble pentacyclic and tetracyclic terpenoids, wherein the water-insoluble terpenoid having a free carboxylic, hydroxy or amino functional group is derivatized on this functional group with a substituent selected from the group comprising substituents of general formula Xa bound to the hydroxy group of the terpenoid, wherein Xa is —OC—R—COOH, substituents of general formula Xa bound to the amino group of the terpenoid, wherein Xa is —OC—R—COOH, quarternary ammonium substituents of general formula Xb bound to the carboxy group of the terpenoid, wherein Xb is —(CH2)nN+R3Y—, quarternary ammonium substituents of general formula Xc bound to the carboxy group of the terpenoid, wherein Xc je —(CH2)nR+Y—, substituents of general formula Xd bound to the carboxy group of the terpenoid, wherein Xd represents —R—COOH, glycosylic substituents Xe bound by alpha or beta glycosidic bond to the hydroxy group or to the carboxy group of the terpenoid, wherein Xe is selected from the group comprising glucosyl, galactosyl, arabinosyl, rhamnosyl, lactosyl, cellobiosyl, maltosyl and the 2-deoxyanalogues thereof, and subsequently, the prepared derivative is dissolved in the solution containing water, a cyclodextrin and optionally pharmaceutically acceptable auxiliary substances, forming an inclusion derivative with the cyclodextrin. Object of the invention is further a soluble formulation of a pentacyclic or tetracyclic triterpenoid, containing an inclusion complex of the derivatized pentacyclic or tetracyclic terpenoid with a cyclodextrin, and optionally water and pharmaceutically acceptable auxiliary substances and further a pharmaceutical composition containing the soluble formulation.
US08653051B2	Use of 3-alpha-androstanediol in combination with a PDE5 inhibitor, in the treatment of sexual dysfunction The invention relates to the field of male and/or female sexual dysfunction. The invention specifically relates to the use of 3-alpha-androstanediol, preferably in combination with a type 5 phosphodiesterase (PDE5) inhibitor.
US08653047B2	Modulation of angiopoietin-like 3 expression Provided herein are methods, compounds, and compositions for reducing expression of an ANGPTL3 mRNA and protein in an animal. Also provided herein are methods, compounds, and compositions for reducing plasma lipids, plasma glucose and atherosclerotic plaques in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate any one or more of cardiovascular disease or metabolic disease, or a symptom thereof.
US08653043B2	Enhanced neoglycosides through neoglycosylation and methods of use thereof Using neoglycosylation, the impact of differential glycosylation upon the divergent anticancer and anti-HIV properties of the triterpenoid betulinic acid (BA) was examined. Each member from a library of 37 differentially glycosylated BA variants was tested for anticancer and anti-HIV activities. Enhanced analogs for both desired activities were discovered with the corresponding antitumor or antiviral enhancements diverging, based upon the appended sugar, into two distinct compound subsets.
US08653041B2	Antibacterial aminoglycoside analogs Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): including stereoisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein Q1 and Q2 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
US08653039B2	Peptide based inhibition of caPCNA interaction in cancer Peptides derived from cancer specific isoform of proliferating cell nuclear antigen (caPCNA, also known as csPCNA) or from nmPCNA-interacting proteins interfere with intracellular protein-protein interaction, thereby causing a reduction in the proliferative potential of cancer. These peptides serve as therapeutic compositions to reduce the proliferation of cancer cells and also augment existing chemotherapeutic methods.
US08653037B2	Proteins that fluoresce at infrared wavelengths or generate singlet oxygen upon illumination This invention provides novel truncation mutants of a phytochrome from the bacterium Deinococcus radiodurans. When expressed either in bacteria or mammalian cells, these mutant phytochromes spontaneously incorporate biliverdin, a ubiquitous intermediate in heme catabolism, and become fluorescent in the infrared (IR) region. These phytochromes are the first genetically encoded labels that can be excited by far-red light and fluorescent in the true IR (>700 nm). If these mutants instead incorporate protoporphyrin IX, an intermediate in heme biosynthesis, illumination now generates significant amounts of singlet oxygen. Singlet oxygen is useful because it can be used to kill individual proteins or cells, detect long-range protein-protein interactions, or generate electron-microscopic contrast. The invention also relates to methods of making and using such proteins and protein variants.
US08653036B2	Methods of treating retinitis pigmentosa The present invention relates to methods of treating retinitis pigmentosa using β-turn peptidomimetic cyclic compounds or derivatives thereof. The β-turn peptidomimetic cyclic compounds can be used alone, in combination and/or in conjunction with one or more other compounds, molecules or drugs useful in treating retinitis pigmentosa.
US08653034B2	Compositions and methods comprising phosphatidylethanolamine-binding peptide derivatives Disclosed are surprising discoveries concerning the role of anionic phospholipids and aminophospholipids in tumor vasculature and in viral entry and spread, and compositions and methods for utilizing these findings in the treatment of cancer and viral infections. Also disclosed are advantageous antibody, immunoconjugate and duramycin-based compositions and combinations that bind and inhibit anionic phospholipids and aminophospholipids, for use in the safe and effective treatment of cancer, viral infections and related diseases.
US08653032B2	Pharmaceutical composition for preventing / treating TRPV1 activity-related and inflammation-related diseases or conditions containing maillard peptide separated from well-aged traditional soy sauce as active ingredient Disclosed is a pharmaceutical composition for preventing or treating TRPV1 activity-related or inflammation-related, diseases or conditions, containing a Maillard peptide separated from well-aged traditional soy sauce as an active ingredient. The Maillard peptide in the present invention functions both as a TRPV1 agonist and a TRPV1 antagonist, and further functions as a TRPV1 activity modulator. Therefore, the Maillard peptide can be used for preventing or treating TRPV1 activity-related diseases such as pain, neurological diseases, urgent defecation, inflammatory bowel disease, respiratory diseases, urinary incontinence, overactive bladder, neurogenic / allergic / inflammatory skin diseases, skin, eye or mucosal irritation, hyperacusis, tinnitus, vestibular hypersensitivity, heart disease, etc. The Maillard peptide can further inhibit COX-2 activity, and therefore can be effectively used for preventing or treating inflammation-related diseases or conditions such as rheumatic fever, influenza, cold, throat pain, headaches, toothaches, sprains, neuralgia, synovitis, rheumatoid arthritis, degenerative arthropathies, gout, ankylosing spondylitis, psoriasis, dermatitis, etc.
US08653030B2	Pharmaceutical formulation composed of a polymer blend and an active compound for time-controlled release A formulation containing a biologically active compound having a chemical structure with hydrogen bonding sites, a first biocompatible, hydrolytically degrading polycarbonate with hydrogen bonding sites and tyrosine-derived diphenol monomer units, and a second biocompatible hydrolytically degrading polymer that is less hydrophobic than the polycarbonate, wherein the second polymer degrades hydrolytically to form acidic degradation products that promote the release of the active compound. Methods for active compound delivery are also disclosed.
US08653029B2	Flowable paste and putty bone void filler The present invention provides a composition that may be used as an implant or a bone graft substitute or extender for filling voids and/or promoting fusion of osseous tissues. The implant may comprise ceramic granules such as calcium phosphate granules and one or more polysaccharide excipients, and may be in the form of a putty or flowable paste. Optionally, the implant may also comprise a growth factor such as a bone morphogenetic protein.
US08653024B2	Use of AMPs for treatment of UTI/cystitis Provided is treatment of urinary tract infections including bladder infections caused by uropathogenic bacterial strains such as for example Escherichia coli with a beta-hairpin antimicrobial Arenicin polypeptide derived from the murine polychaeta Arenicola marina. Also provided are variants of Arenicin for treatment of urinary tract infections.
US08653023B1	Dual beneficial effect of dopamine enhancing and neuroprotective actions of PKC delta inhibitors for treatment of Parkinson's disease The present invention describes novel pharmaceutical compositions and methods for treatment of diseases, disorders, or conditions characterized by dopamine deficiency, including Alzheimer's disease, Parkinson's disease, Tourette's syndrome, schizophrenia, Huntington's disease, symptoms of attention deficit hyperactivity disorder, drug abuse and clinical depression. The treatment of the present invention utilizes PKCd inhibitors that have the dual benefit of increasing the levels of dopamine in the central nervous system while also protecting neuronal cells from neurodegeneration. The method and pharmaceutical compositions can be used to treat diseases, disorders, or conditions associated with neurodegeneration such as Parkinson's disease, Huntingson's disease, Alzheimer's disease, Parkinson's disease, cerebral ischemia, myocardial ischemia, spinal muscular atrophy, multiple sclerosis, AIDS-related encephalitis, HIV-related encephalitis, aging, alopecia, and neurological damage due to stroke, Huntington disease (HD), amyotrophic lateral sclerosis (ALS), cardiovascular diseases, inflammatory diseases, spinal cord trauma, and head injury.
US08653022B2	Use of ghrelin splice variant for treating hypercholesterolemia and/or high cholesterol and/or high cholesterol complication and/or lipemia and/or lipemia complication and/or coronary heart disease and/or weight management and/or diabetes and/or hyperglycemia The present disclosure relates, in one aspect, to use of ghrelin splice variant or an analogue thereof for the preparation of a medicament for one or more of: treatment and/or prevention of hypercholesterolemia and/or high cholesterol and/or high cholesterol complication and/or lipemia and/or lipemia complication and/or CHD and/or weight management and/or diabetes and/or hyperglycemia.
US08653021B2	Targeting PAX2 for the treatment of breast cancer The present application provides methods of prevention and/or treatment of breast cancer in a subject by inhibiting expression of PAX2. In the cancer treatment methods disclosed, the method of inhibiting expression of PAX2 can be by administration of a nucleic acid encoding an siRNA for PAX2. A method of treating cancer in a subject by administering DEFB1 is also provided. Similarly, provided is a method of treating cancer in a subject by increasing expression of DEFB1 in the subject.
US08653020B2	Selective exosite inhibition of PAPP-A activity against IGFBP-4 The present invention relates in one embodiment to PAPP-A exosite(s) interactors such as antibodies which bind to a region comprising LNR3 of PAPP-A and efficiently inhibit proteolysis of IGFBP-4, but not -5. The region comprising LNR3 represents a substrate binding exosite, which can be targeted for selective proteolytic inhibition. Accordingly, the present invention relates in one embodiment to differential inhibition of natural protease substrates by exosite targeting.
US08653014B2	Shampoo composition containing a gel network A shampoo composition having from about 5% to about 50% of a combination of sodium lauryl sulfate and sodium laureth-n sulfate, less than 3.82% of sodium laureth-n sulfate having n>1. The shampoo composition further includes from about 0.5% to about 3% of a co-surfactant selected from the group consisting of amphoteric, zwitterionic, and nonionic surfactants. The shampoo composition has a dispersed gel network phase having at least 0.05% of one or more fatty alcohols, at least 0.01% of one or more secondary surfactants, and water. The shampoo composition further includes at least about 20% of an aqueous carrier. The shampoo composition further has an enthalpy of transition from about 0 J/g to about 0.2 J/g as measured according to differential scanning calorimetry in a peak melt transition temperature range between about 18° C. to about 30° C.
US08653013B2	Nontoxic low melting point fusible alloy lubrication of electromagnetic railgun armatures and rails A railgun which has a conductive lubricant and system of delivery reduces the electrical resistance and friction of the armature-rail sliding contact, thereby decreasing the amount of heat generated at the electrical contact. The conductive lubricant may be a ternary alloy of bismuth, indium and tin. The system of delivery for the conductive lubricant may include a plurality of surface reservoirs formed in either the rail surface, the armature face, or both.
US08653011B2	Gelled hydrocarbon system and method with dual-function viscosifier/breaker additive A gelled organic-based fluid system and method of forming and using the system. The fluid system is prepared by gelling an organic solvent, a viscoelastic surfactant, and a nitrogen compound having a free electron pair such as urea in an amount effective to both increase viscosity and increase a rate of breaking the viscosity, relative to the gelled system without the nitrogen compound. In a further aspect, the method is used to treat a well penetrating a subterranean formation, for example, in a coiled tubing cleanout, or the like.
US08653009B2	Method for preventing the formation of calcium carboxylate deposits in the dewatering process for crude oil/water streams The invention relates to the use of compounds comprising three hydrophobic groups as additives to a stream of crude oil containing carboxylic acids, in particular naphthenic acids, and salt water, to prevent the formation of calcium carboxylates when the fluid is exposed to shear forces. Preferably, the compounds are added to a crude oil/water stream containing organic acids Ca2+ ions at a point between the well and the pressure reduction valve in the crude oil receiving station. The compounds have the formula (I) wherein hydrophobic groups R, R′, and R″ are, independently, an optionally substituted hydrocarbyl group or an optionally substituted acyl group having 4-22 carbon atoms; X is N, P═O or CR′″, wherein R′″ is H or a C1-C4 alkyl group; Y is C═O or CH2; a, a′, a″ b, b′ and b″ each independently are 0 or 1, the subscript 0-1 meaning that if the subscript is 0, then the group is not present in the molecule, whereas if the subscript is 1, then the group is present in the molecule; n, n′, and n″ are, independently, zero or on average at least 1, and at most 14; the sum of n, n′, and n″ is 0 or on average at least 3, and at most 42; and m, m′, and m″ are, independently, on average 0-6, and the sum of m, m′, and m″ is 0-18.
US08653008B2	Well treatment A method for delivering a scale treatment agent to a hydrocarbon producing system. The method includes the steps of contacting the system with a foam comprising the scale treatment agent, and shutting the scale treatment agent in the system for at least 0.5 hour.
US08653003B2	Pyrazol-4-yl carboxamide derivatives as microbiocides Compounds of formula (I) wherein R1 is C1-C4alkyl, C1-C4haloalkyl or C1-C4alkoxy; R2 is C1-C4alkyl; R3 is hydrogen or halogen; R4 is hydrogen, C1-C4alkyl or C1-C4halogenalkyl; R5 is hydrogen, halogen or C1-C4alkyl; R6 is hydrogen, halogen, C1-C4alkyl, C2-C6alkenyl or C3-C6alkynyl; R7 is hydrogen, halogen, C1-C6alkyl, C2-C6alkenyl, C3-C6alkynyl, C3-C6cycloalkyl-C3-C6alkynyl, C1-C6haloalkyl, C1-C6haloalkoxy, C2-C6haloalkenyl, or C2-C6haloalkenyloxy; R5 is hydrogen, halogen, C1-C4alkyl, C2-C6alkenyl, C3-C6alkynyl, amino, C1-C6alkylcarbonylamino, C1-C6alkoxycarbonylamino or C3-C6cycloalkylcarbonylamino; R9 is hydrogen, halogen, C1-C6alkyl, C1-C6alkoxy, C2-C6alkenyl, C3-C6alkynyl, C3-C6cycloalkyl-C3-C6alkynyl, halophenoxy, halophenyl, C1-C6haloalkyl, C1-C6haloalkoxy, C2-C6haloalkenyl, or C2-C6haloalkenyloxy; R10 is hydrogen, halogen, C1-C4alkyl, C1-C6alkoxy, C2-C6alkenyl or C3-C6alkynyl; X is CH2, O or S; n is 0, 1 or 2; and agronomically acceptable salts/isomers/structural isomers/stereoisomers/diastereoisomers/enantiomers/tautomers and N-oxides of those compounds, are suitable for use as microbiocides.
US08652996B2	Irreversible thermochromic pigment capsules Disclosed herein are irreversible thermochromic ink compositions including a solvent and a sublimable dye dissolved in the solvent. The solvent and the sublimable dye can be, optionally, encapsulated. Written marks made with the thermochromic ink compositions can be subjected to a force directing component and/or a heat source, to promote sublimation of the sublimable dye, thereby causing the written mark to change color or become substantially colorless.
US08652992B2	Pinning and affixing nano-active material A nanoparticle comprises a nano-active material and a nano-support. In some embodiments, the nano-active material is platinum and the nano-support is alumina. Pinning and affixing the nano-active material to the nano-support is achieved by using a high temperature condensation technology. In some embodiments, the high temperature condensation technology is plasma. Typically, a quantity of platinum and a quantity of alumina are loaded into a plasma gun. When the nano-active material bonds with the nano-support, an interface between the nano-active material and the nano-support forms. The interface is a platinum alumina metallic compound, which dramatically changes an ability for the nano-active material to move around on the surface of the nano-support, providing a better bond than that of a wet catalyst. Alternatively, a quantity of carbon is also loaded into the plasma gun. When the nano-active material bonds with the nano-support, the interface formed comprises a platinum copper intermetallic compound, which provides an even stronger bond.
US08652990B2	Method for producing catalyst for purification of exhaust gas Provided is a method for producing a catalyst for purification of exhaust gas, including the steps of: adding Zr ions to a solution containing a platinum hydroxide polymer; diluting the solution to which the Zr ions are added by using an aqueous ammonium acetate solution; immersing a support made of Al2O3, SiO2, CeO2, ZrO2, or a composite oxide of any ones of these oxides in the diluted solution, followed by heating at 60 to 70° C., to thereby support the platinum hydroxide polymer on the support; and calcining the support, on which the platinum hydroxide polymer is supported, at 150 to 800° C.
US08652989B2	Photocatalyst and reducing catalyst using the same To provide a photocatalyst having high selectivity and carrying out a reductive reaction with light having a longer wavelength. A photocatalyst has a structure in which a semiconductor and a substrate are joined, in which the substrate causes a catalytic reaction by transfer to the substrate of excited electrons, which are generated by applying light to the semiconductor.
US08652981B2	Dense silicon nitride body having high strength, high Weibull modulus and high fracture toughness Silicon nitride materials with high strength, fracture toughness values, and Weibull moduli simultaneously, due to unique large grain reinforcing microstructures and well engineered grain boundary compositions. The invention demonstrates that, surprisingly and contrary to prior art, a silicon nitride material can be made which simultaneously has high strength above about 850-900 MPa, a Weibull above about 15 and high fracture toughness (above about 8 and 9 MPa·m1/2), and has reinforcing grains longer than 5 μm, typically longer than 10 μm in the microstructure without compromising its properties and reliability. The product of this invention can be processed using a variety of densification methods, including gas-pressure sintering, hot pressing, hot isostatic pressing, but is not limited to these, and does not require multiple heat treatments for all of these features to be achieved.
US08652979B2	Tempered glass substrate Provided is a glass substrate satisfying ion exchange performance and devitrification resistance of a glass simultaneously and having higher mechanical strength compared to a conventional glass substrate. A tempered glass substrate which has a compression stress layer on a surface thereof, has a glass composition including, in terms of mole %, 50 to 85% of SiO2, 5 to 30% of Al2O3, 0 to 20% of Li2O, 0 to 20% of Na2O, 0 to 20% of K2O, 0.001 to 10% of TiO2, and 15 to 35% of Li2O+Na2O+K2O+Al2O3, has a (Li2O+Na2O+K2O)/Al2O3 value of 0.7 to 3 in terms of mole fraction, and is substantially free of As2O3 and F.
US08652970B2	Vacuum processing method and vacuum processing apparatus A processing gas is introduced to remove an oxide film on the surface of a silicon substrate 5. F radicals are allowed to act on the surface of the silicon substrate to etch a silicon layer. Then, NH3 gas, N2 gas and NF3 gas are introduced, allowing NHxFy to act on the oxidized surface of the silicon substrate 5, thereby forming (NH4)2SiF6. The resulting (NH4)2SiF6 is sublimated to remove by-products (SiOF, SiOH) on the surface of the silicon substrate 5.
US08652965B2	Production method for thick film metal electrode and production method for thick film resist One object of the present invention is to provide a method for producing a thick film metal electrode that is able to form a positive-negative reverse type resist, which has a thickness of 7 μm or more and excellent in-plane uniformity, on the circuit element formed on the silicon carbide substrate, and a method for producing a thick film resist, and the present invention provides a method for producing a thick film resist wherein a first positive-negative reverse type resist having a first viscosity is formed on an upper surface of a circuit element layer which is treated with HMDS, and a second positive-negative reverse type resist having a second viscosity, which is larger than the first viscosity, on the first positive-negative reverse type resist such that a total thickness of the first and second positive-negative reverse type resists constituting a thick film resist be 7 μm or more.
US08652963B2	MOSFET integrated circuit with uniformly thin silicide layer and methods for its manufacture An MOSFET device having a Silicide layer of uniform thickness, and methods for its fabrication, are provided. One such method involves depositing a metal layer over wide and narrow contact trenches on the surface of a silicon semiconductor substrate. Upon formation of a uniformly thin amorphous intermixed alloy layer at the metal/silicon interface, the excess (unreacted) metal is removed. The device is annealed to facilitate the formation of a thin silicide layer on the substrate surface which exhibits uniform thickness at the bottoms of both wide and narrow contact trenches.
US08652959B2	n- and p-channel field effect transistors with single quantum well for complementary circuits A complementary metal oxide semiconductor (CMOS) device in which a single InxGa1-xSb quantum well serves as both an n-channel and a p-channel in the same device and a method for making the same. The InxGa1-xSb layer is part of a heterostructure that includes a Te-delta doped AlyGa1-ySb layer above the InxGa1-xSb layer on a portion of the structure. The portion of the structure without the Te-delta doped AlyGa1-ySb barrier layer can be fabricated into a p-FET by the use of appropriate source, gate, and drain terminals, and the portion of the structure retaining the Te-delta doped AlyGa1-ySb layer can be fabricated into an n-FET so that the structure forms a CMOS device, wherein the single InxGa1-xSb quantum well serves as the transport channel for both the n-FET portion and the p-FET portion of the heterostructure.
US08652954B2	Method for manufacturing silicon carbide semiconductor device A method for manufacturing a silicon carbide semiconductor device includes the step of forming a mask pattern of a silicon oxide film by removing a portion of the silicon oxide film by means of etching employing a gas containing oxygen gas and at least one fluorine compound gas selected from a group consisting of CF4, C2F6, C3F8, and SF6.
US08652948B2	Nitride semiconductor, nitride semiconductor crystal growth method, and nitride semiconductor light emitting element During the growth of a nitride semiconductor crystal on a nonpolar face nitride substrate, such as an m-face, the gas that constitutes the main flow in the process of heating up to a relatively high temperature range, before growth of the nitride semiconductor layer, (the atmosphere to which the main nitride face of the substrate is exposed) and the gas that constitutes the main flow until growth of first and second nitride semiconductor layers is completed (the atmosphere to which the main nitride face of the substrate is exposed) are primarily those that will not have an etching effect on the nitride, while no Si source is supplied at the beginning of growth of the nitride semiconductor layer. Therefore, nitrogen atoms are not desorbed from near the nitride surface of the epitaxial substrate, thus suppressing the introduction of defects into the epitaxial film. This also makes epitaxial growth possible with a surface morphology of excellent flatness.
US08652946B2	Graphene layer formation on a carbon based substrate A system and method for forming graphene layers on a substrate. The system and methods include direct growth of graphene on diamond and low temperature growth of graphene using a solid carbon source.
US08652936B2	Vertical cavity surface emitting devices incorporating wafer fused reflectors A method of forming an optoelectronic device comprising growing a first multi-layer 2 representing a reflector on a first substrate and a second multilayer 4 representing an active region on a second substrate, the first and second substrates being lattice mismatched, fusing the first multi-layer 2 to a third substrate 3, wherein the material of the third substrate 3 is lattice matched with respect to the material of the second multi-layer 4, removing the first substrate to expose the first multi-layer 2, and fusing the first multi-layer to the second multi-layer 4.
US08652933B2	Semiconductor structure having wide and narrow deep trenches with different materials Disclosed is a method of forming a semiconductor device structure in a semiconductor layer. The method includes forming a first trench of a first width and a second trench of a second width in the semiconductor layer; depositing a layer of first material which conforms to a wall of the first trench but does not fill it and which fills the second trench; removing the first material from the first trench, the first material remaining in the second trench; depositing a second material into and filling the first trench and over a top of the first material in the second trench; and uniformly removing the second material from the top of the first material in the second trench, wherein the first trench is filled with the second material and the second trench is filled with the first material and wherein the first material is different from the second material.
US08652928B2	Method of manufacturing a semiconductor device A semiconductor device includes a substrate having a first area and a second area, a first transistor in the first area, a second transistor in the second area, an isolation layer between the first area and the second area, and at least one buried shield structure on the isolation layer.
US08652924B2	Methods of fabricating a storage node in a semiconductor device and methods of fabricating a capacitor using the same A storage node is formed in a semiconductor device by forming an interlayer insulation layer on a substrate, forming an etch stop layer and a first sacrificial layer on the interlayer insulation layer, patterning the first sacrificial layer and the etch stop layer to form a first sacrificial layer pattern and an etch stop layer pattern that define a storage node contact hole, forming a recessed first storage node conductive pattern that conformally covers a lower sidewall and a bottom surface of the storage node contact hole, forming a second storage node conductive pattern that includes a first portion surrounded by the recessed first storage node conductive pattern and a second portion conformally covering an upper sidewall of the storage node contact hole, and removing the first sacrificial layer pattern. The recessed first storage node conductive pattern and the second storage node conductive pattern constitute a storage node.
US08652921B2	Semiconductor device having a damp-proof structure and method of fabricating the same A semiconductor device has a substrate that includes a cell array region and a dummy pattern region surrounding the cell array region. The cell array region includes a cell structure having a plurality of cell active pillars extending in a vertical direction from the cell array region of the substrate and includes cell gate patterns and cell gate interlayer insulating patterns alternately stacked on the substrate. The cell gate patterns and cell gate interlayer insulating patterns have sides facing the cell active pillars. The dummy pattern region includes a damp-proof structure.
US08652920B2	Substrate with embedded patterned capacitance A process for forming a laminate with capacitance and the laminate formed thereby. The process includes the steps of providing a substrate and laminating a conductive foil on the substrate wherein the foil has a dielectric. A conductive layer is formed on the dielectric. The conductive foil is treated to electrically isolate a region of conductive foil containing the conductive layer from additional conductive foil. A cathodic conductive couple is made between the conductive layer and a cathode trace and an anodic conductive couple is made between the conductive foil and an anode trace.
US08652913B2	Method for forming silicon/germanium containing drain/source regions in transistors with reduced silicon/germanium loss By providing a protection layer on a silicon/germanium material of high germanium concentration, a corresponding loss of strained semiconductor material may be significantly reduced or even completely avoided. The protection layer may be formed prior to critical cleaning processes and may be maintained until the formation of metal silicide regions. Hence, high performance gain of P-type transistors may be accomplished without requiring massive overfill during the selective epitaxial growth process.
US08652911B2	Semiconductor device and method of manufacturing the same A method of fabricating a semiconductor device includes forming a device isolation region on a semiconductor substrate to define an active region, forming a gate electrode on the active region and the device isolation region across the active region, and forming at least one gate electrode opening portion in the gate electrode so as to overlap an edge portion of the active region, wherein the gate electrode opening portion is simultaneously formed with the gate electrode.
US08652906B2	Method for manufacturing a semiconductor device and semiconductor device A method for manufacturing a semiconductor device and semiconductor device. One embodiment provides a semiconductor substrate with an active region and a margin region bordering on the active region. The spacer layer in the margin region is broken through at a selected location and at least part of the spacer layer is removed in the active region using a common process. The location is selected such that at least part of the semiconductor mesa structure is exposed and the spacer layer in the margin region is broken through to the conductive layer and not to the semiconductor substrate.
US08652901B1	Single-mask spacer technique for semiconductor device features A method for fabricating vertical surround gate structures in semiconductor device arrays. The method includes forming pillars separated by vertical and horizontal trenches on a substrate. Forming a gate layer over the pillars and trenches such that the gate layer forms gate trenches in the horizontal trenches. The method includes forming fillers within the gate trenches, and planarizing the gate layer and fillers. The method also includes successively etching a first portion of the gate layer, removing the fillers, and etching a second portion of the gate layer.
US08652900B2	Trench MOSFET with ultra high cell density and manufacture thereof A trench MOSFET structure with ultra high cell density is disclosed, wherein the source regions and the body regions are located in different regions to save the mesa area between every two adjacent gate trenches in the active area. Furthermore, the inventive trench MOSFET is composed of stripe cells to further increase cell packing density and decrease on resistance Rds between the drain region and the source region.
US08652897B2	Semiconductor memory devices and methods of fabricating the same Provided are semiconductor memory devices and the methods of fabricating the same. The method may include forming a plurality of diode patterns in each of a plurality of first trenches, each of the plurality of first trenches including at least two active regions, the plurality of diode patterns occupying a plurality of spaces, treating the plurality of diode patterns to form a plurality of semiconductor patterns in each of the plurality of spaces, removing portions of the plurality of semiconductor patterns to form a recess in each of the plurality of spaces, treating the of the plurality of semiconductor patterns to form a plurality of diodes in each of the plurality of spaces, forming a bottom electrode on each of the plurality of diodes, forming a plurality of memory elements on each of the bottom electrodes, and forming a plurality of upper interconnection lines on the plurality of memory elements.
US08652896B2	Semiconductor memory device and fabrication process thereof A SRAM includes a first CMOS inverter of first and second MOS transistors connected in series, a second CMOS inverter of third and fourth MOS transistors connected in series and forming a flip-flop circuit together with the first CMOS inverter, and a polysilicon resistance element formed on a device isolation region, each of the first and third MOS transistors is formed in a device region of a first conductivity type and includes a second conductivity type drain region at an outer side of a sidewall insulation film of the gate electrode with a larger depth than a drain extension region thereof, wherein a source region is formed deeper than a drain extension region, the polysilicon gate electrode has a film thickness identical to a film thickness of the polysilicon resistance element, the source region and the polysilicon resistance element are doped with the same dopant element.
US08652894B2	Method for fabricating a FinFET device A FinFET device and method for fabricating a FinFET device is disclosed. An exemplary method includes forming a fin structure on a semiconductor substrate and forming a gate structure on the fin structure. A capping layer is then formed over the semiconductor substrate, fin structure, and gate structure. The capping layer is patterned to form an opening exposing a second portion of the fin structure. An epitaxial layer is grown in the opening and on the second portion of the fin structure. At least one of a source region and a drain region is provided in the epitaxial layer. The method may continue to remove the capping layer.
US08652892B2	Implant damage control by in-situ C doping during sige epitaxy for device applications Some example embodiments of the invention comprise methods for and semiconductor structures comprised of: a MOS transistor comprised of source/drain regions, a gate dielectric, a gate electrode, channel region; a carbon doped SiGe region that applies a stress on the channel region whereby the carbon doped SiGe region retains stress/strain on the channel region after subsequent heat processing.
US08652890B2	Methods for fabricating integrated circuits with narrow, metal filled openings Methods are provided for fabricating an integrated circuit that includes metal filled narrow openings. In accordance with one embodiment a method includes forming a dummy gate overlying a semiconductor substrate and subsequently removing the dummy gate to form a narrow opening. A layer of high dielectric constant insulator and a layer of work function-determining material are deposited overlying the semiconductor substrate. The layer of work function-determining material is exposed to a nitrogen ambient in a first chamber. A layer of titanium is deposited into the narrow opening in the first chamber in the presence of the nitrogen ambient to cause the first portion of the layer of titanium to be nitrided. The deposition of titanium continues, and the remaining portion of the layer of titanium is deposited as substantially pure titanium. Aluminum is deposited overlying the layer of titanium to fill the narrow opening and to form a gate electrode.
US08652889B2	Fin-transistor formed on a patterned STI region by late fin etch When forming sophisticated semiconductor devices, three-dimensional transistors in combination with planar transistors may be formed on the basis of a replacement gate approach and self-aligned contact elements by forming the semiconductor fins in an early manufacturing stage, i.e., upon forming shallow trench isolations, wherein the final electrically effective height of the semiconductor fins may be adjusted after the provision of self-aligned contact elements and during the replacement gate approach.
US08652885B2	Method of fabricating thin film transistor A method of fabricating a thin film transistor includes forming an active layer on an insulating substrate; forming a gate insulation film on the insulating substrate; forming source, drain, and body contact regions which are separated by a channel region in the active layer; forming a gate on the gate insulation film; forming an interlayer insulation film on the insulating substrate; and forming source and drain electrodes electrically connected with the source and drain regions, respectively, wherein a voltage is applied to the channel region of the active layer through the body contact region, and the body contact region is connected to the source or drain electrode.
US08652883B1	Methods of manufacture of bottom port surface mount silicon condenser microphone packages The present invention relates to a surface mount package for a silicon condenser microphone and methods for manufacturing the surface mount package. The surface mount package uses a limited number of components which simplifies manufacturing and lowers costs, and features a substrate that performs functions for which multiple components were traditionally required, including providing an interior surface on which the silicon condenser die is mechanically attached, providing an interior surface for making electrical connections between the silicon condenser die and the package, and providing an exterior surface for surface mounting the package to a device's printed circuit board and for making electrical connections between package and the device's printed circuit board.
US08652882B2	Chip package structure and chip packaging method A chip packaging method includes the steps of: attaching a first tape to a metal plate; patterning the metal plate to form a plurality of terminal pads and a plurality of leads, wherein the plurality of terminal pads and the plurality of leads are disposed on two opposite sides of a central void region, the plurality of terminal pads on each side are arranged in at least two rows spaced apart from each other in the direction away from the central void region, and each lead has a first end portion extending to the central void region and a second end portion connecting to a corresponding terminal pad; attaching a second tape having openings to the plurality of terminal pads, wherein each of the openings exposes the central void region and the first end portions of the leads; removing the first tape; attaching a chip to the plurality of terminal pads and the plurality of leads, wherein a plurality of bond pads on the chip are corresponding to the central void region; and connecting the bond pads to the first end portions of the leads with a plurality of bonding wires through the opening.
US08652881B2	Integrated circuit package system with anti-peel contact pads An integrated circuit package system includes: forming an anti-peel pad having both a concave ring and an external terminal with the concave ring, having a peripheral wall, surrounding the external terminal; connecting an integrated circuit with the anti-peel pad; and forming an encapsulation over the integrated circuit, the concave ring, and the external terminal with the encapsulation under the peripheral wall.
US08652879B2	Lead frame ball grid array with traces under die A package includes a first plated area, a second plated area, a die attached to the first plated area, and a bond coupling the die to the second plated area. The package further includes a molding encapsulating the die, the bond, and the top surfaces of the first and second plated areas, such that the bottom surfaces of the first and second plated areas are exposed exterior to the package. Additional embodiments include a method of making the package.
US08652878B2	Stress-engineered interconnect packages with activator-assisted molds A method includes providing a pad chip having contact pads, providing a spring chip having micro-springs, applying a chemical activator to one of either the pad chip or the spring chip, applying an adhesive responsive to the chemical activator on the other of the pad chip or the spring chip, aligning the pad chip to the spring chip such that the micro-springs will contact the contact pads, and pressing the pad chip and the spring chip together such that the chemical activator at least partially cures the adhesive.
US08652877B2	Method of manufacturing layered chip package A layered chip package includes a main body, and wiring that includes a plurality of wires disposed on a side surface of the main body. The main body includes a plurality of stacked layer portions. A method of manufacturing the layered chip package includes the step of fabricating a layered substructure and the step of cutting the layered substructure. The layered substructure includes: a plurality of arrayed pre-separation main bodies; a plurality of accommodation parts disposed between two adjacent pre-separation main bodies; and a plurality of preliminary wires accommodated in the accommodation parts. The accommodation parts are formed in a photosensitive resin layer by photolithography. In the step of cutting the layered substructure, the plurality of pre-separation main bodies are separated from each other, and the wires are formed by the preliminary wires.
US08652876B2	Method of manufacturing pram using laser interference lithography A method of manufacturing a phase-change random access memory includes: sequentially depositing an insulating layer, a first electrode layer, a phase change material layer, and a transfer material layer on a substrate; forming an array pattern in the transfer material layer using a laser interference lithography process; forming a metal layer on the transfer material layer having the array pattern formed; forming a second electrode layer by removing the transfer material layer; and forming a phase change layer by etching the phase change material layer using the second electrode layer as a mask. Accordingly, the manufacturing process of the phase-change random access memory may achieve an increase in speed and may be simplified.
US08652875B2	Method of manufacturing a thin-film transistor A method of manufacturing a thin film transistor is provided. The method includes forming a lower organic semiconductor layer, forming an upper organic semiconductor layer on the lower organic semiconductor layer, the upper organic semiconductor layer having solubility and conductivity higher than those of the lower organic semiconductor layer, forming a source electrode and a drain electrode spaced apart from each other and respectively overlapping the upper organic semiconductor layer, and dissolving the upper organic semiconductor layer selectively by using the source electrode and the drain electrode as a mask.
US08652873B1	Thick-film paste containing lead-vanadium-based oxide and its use in the manufacture of semiconductor devices The present invention provides a thick-film paste for printing the front side of a solar cell device having one or more insulating layers and a method for doing so. The thick-film paste comprises a source of an electrically conductive metal and a lead-vanadium-based oxide dispersed in an organic medium. The invention also provides a semiconductor device comprising an electrode formed from the thick-film paste.
US08652872B2	Solar cells and method of manufacturing thereof A photovoltaic cell, the cell comprising: a silicon substrate of bulk silicon material having front and rear surfaces; an emitter layer on the rear surface of said substrate; elongate channels through the emitter layer; elongate contacts to the bulk of the silicon substrate within at least some of the elongate channels, wherein the contacts are narrower than the channels; and gaps in the emitter between at least some of the elongate contacts and the emitter layer on the sides of the contacts.
US08652871B2	Method for depositing an amorphous silicon film for photovoltaic devices with reduced light-induced degradation for improved stabilized performance A thin film photovoltaic device on a substrate is being realized by a method for manufacturing a p-i-n junction semiconductor layer stack with a p-type microcrystalline silicon layer, a p-type amorphous silicon layer, a buffer silicon layer comprising preferably intrinsic amorphous silicon, an intrinsic type amorphous silicon layer, and an n-type silicon layer over the intrinsic type amorphous silicon layer.
US08652867B2	Micrometer-scale grid structure based on single crystal silicon and method of manufacturing the same The present invention discloses a micrometer-scale grid structure based on single crystal silicon consists of periphery frame 1 and grid zone 2. The periphery frame 1 is rectangle, and grid zone 2 has a plurality of mesh-holes 3 distributing in the plane of grid zone 2. The present invention also provides a method for manufacturing a micrometer-scale grid structure based on single crystal silicon. According to the present invention thereof, the contradiction between demand of broad deformation space for sensor and actuator and the limit of the thickness of sacrifice layer is solved. Furthermore, the special requirement of double-side transparence for some optical sensor is met.
US08652864B2	Solid-state image pickup device and method for producing the same A solid-state image pickup device includes an element isolation insulating film electrically isolating pixels on the surface of a well region; a first isolation diffusion layer electrically isolating the pixels under the element isolation insulating film; and a second isolation diffusion layer electrically isolating the pixels under the first isolation diffusion layer, wherein a charge accumulation region is disposed in the well region surrounded by the first and second isolation diffusion layers, the inner peripheral part of the first isolation diffusion layer forms a projecting region, an impurity having a conductivity type of the first isolation diffusion layer and an impurity having a conductivity type of the charge accumulation region are mixed in the projecting region, and a part of the charge accumulation region between the charge accumulation region and the second isolation diffusion layer is abutted or close to the second isolation diffusion layer under the projecting region.
US08652861B1	HPC optimization of contacts to optoelectronic devices HPC techniques are applied to the screening and evaluating the materials, process parameters, process sequences, and post deposition treatment processes for the development of ohmic contact stacks for optoelectronic devices. Simple test structures are employed for initial screening of basic materials properties of candidate materials for each layer within the stack. The use of multiple site-isolated regions on a single substrate allows many material and/or process conditions to be evaluated in a timely and cost effective manner. Interactions between the layers as well as interactions with the substrate can be investigated in a straightforward manner.
US08652860B2	Packaging photon building blocks having only top side connections in a molded interconnect structure Standardized photon building blocks are packaged in molded interconnect structures to form a variety of LED array products. No electrical conductors pass between the top and bottom surfaces of the substrate upon which LED dies are mounted. Microdots of highly reflective material are jetted onto the top surface. Landing pads on the top surface of the substrate are attached to contact pads disposed on the underside of a lip of the interconnect structure. In a solder reflow process, the photon building blocks self-align within the interconnect structure. Conductors in the interconnect structure are electrically coupled to the LED dies in the photon building blocks through the contact pads and landing pads. Compression molding is used to form lenses over the LED dies and leaves a flash layer of silicone covering the landing pads. The flash layer laterally above the landing pads is removed by blasting particles at the flash layer.
US08652856B2	Method for use in making electronic devices having thin-film magnetic components Disclosed herein is a method of forming electronic device having thin-film components by using trenches. One or more of thin-film components is formed by depositing a thin-film in the trench followed by processing the deposited thin-film to have the desired thickness.
US08652855B2	Low resistance stacked annular contact An integrated circuit contains lower components in the substrate, a PMD layer, upper components over the PMD layer, lower contacts in the PMD layer connecting some upper components to some lower components, an ILD layer over the upper components, metal interconnect lines over the ILD layer, and upper contacts connecting some upper components to some metal interconnect lines, and also includes annular stacked contacts of lower annular contacts aligned with upper annular contacts. The lower contacts and upper contacts each have a metal liner and a contact metal on the liner. The lower annular contacts have at least one ring of liner metal and contact metal surrounding a pillar of PMD material, and the upper contacts have at least one ring of liner metal and contact metal surrounding a pillar of ILD material. The annular stacked contacts connect the metal interconnects to the lower components.
US08652853B2	Hybrid preconcentrator for detection of materials A device having: one or more substrates in an enclosure having an inlet and an outlet; a template directed molecular imprinted material on the substrates; and a heater to heat the material. A method of: providing the above device including a sensor coupled to the outlet; flowing a gas though the device; heating the material; and flowing any vapor evolved from the material into the sensor.
US08652850B2	Method of quantitatively determining 8-isoprostane A method of quantitatively determining 8-isoprostane is provided that includes fluorescently labeling 8-isoprostane with a quinoxalinone derivative in an excess amount relative to 8-isoprostane, separating a fluorescently labeled 8-isoprostane from a unreacted quinoxalinone derivative by contacting a reaction mixture containing the fluorescently labeled 8-isoprostane and the unreacted quinoxalinone derivative with a cation exchange support having a sulfonic acid or a sulfonate immobilized thereon, and quantitatively determining the fluorescently labeled 8-isoprostane that has been separated from the unreacted quinoxalinone derivative.
US08652846B2	Medium derived from stem cells as a pharmaceutical composition The invention provides an apoptosis-modulating cell-free composition comprising conditioned extracellular medium of a stem cell and uses thereof, particularly therapeutic uses. Also provided is a method of obtaining such a composition and an in vitro method of modulating apoptosis.
US08652843B2	DDR1-binding agents and methods of use thereof Disclosed are DDR1 binding agents and methods of using the agents for treating diseases such as cancer. The disclosure provides antibodies that specifically bind to an extracellular domain of DDR1 and modulate DDR1 activity. The disclosure further provides methods of using agents that modulate the activity of DDRI, such as antibodies that specifically bind DDR1, to reduce the tumorigenicity of tumors comprising cancer stem cells by reducing the frequency or number of cancer stem cells in the tumor. Also described are methods of treating cancer comprising administering a therapeutically effect amount of an agent or antibody of the present invention to a patient having a tumor or cancer.
US08652842B2	Humanized immunoglobulin loci The present invention concerns methods and means to produce humanized antibodies from transgenic non-human animals. The invention specifically relates to novel immunoglobulin heavy and light chain constructs, recombination and transgenic vectors useful in making transgenic non-human animals expressing humanized antibodies, transgenic animals, and humanized immunoglobulin preparations.
US08652838B2	Platensimycin biosynthetic gene cluster of Streptomyces platensis The present invention relates to the cloning and sequence of a biosynthetic gene cluster from Streptomyces platensis that produces platensimycin and platencin. Also provided are engineered micro-organisms for the production of these compounds, and analogs thereto, as well as methods of screening for compounds with anti-bacterial activity.
US08652836B2	Defective ribosomal products in blebs (DRibbles) and methods of use to stimulate an immune response Methods are disclosed for producing defective ribosomal products (DRiPs) in blebs (DRibbles) by contacting cells with a proteasome inhibitor, and in some examples also an autophagy inducer, thereby producing treated cells. DRibbles can be used to load antigen presenting cells (APCs), thereby allowing the APCs to present the DRiPs and antigenic fragments thereof. Immunogenic compositions that include treated cells, isolated DRibbles, or DRibble-loaded APCs are also disclosed. Methods are also provided for using treated cells, isolated DRibbles, or DRibble-loaded APCs to stimulate an immune response, for example in a subject. For example, DRibbles obtained from a tumor cell can be used to stimulate an immune response against the same type of tumor cells in the subject. In another example, DRibbles obtained from a pathogen-infected cell or cell engineered to express one or more antigens of a pathogen can be used to stimulate an immune response against the pathogen in the subject.
US08652835B2	Device and method for the mechanical decollation of cells from a cell composite A device for mechanically decollating cells from a cell composite, particularly a shear rotor, a cell isolation unit including such a shear rotor and a method for decollating cells from a cell composite. The aforementioned device includes a rotor having a rotor wall, which is concentrically arranged in a receptacle. A rotor seat is connected to a motor and to which the rotor can be fixed in a detachable manner. A rotational movement of the motor can be transmitted to the rotor by means of the rotor seat. The rotor tapers longitudinally towards the bottom of the receptacle so that different circumferential speeds of the rotor can be transmitted to a liquid sample in the receptacle via the rotor wall.
US08652834B2	Culturing apparatus A culturing apparatus has a culture vessel having a first elastic seal bonded on its upper surface and a culture space formed thereon, and a joint for supplying solution such as a medium to the culture vessel and a second elastic seal having microprojection formed at the lower face. The first elastic seal has a valve for supplying or discharging solution. The second elastic seal is formed with microprojection at the position corresponding to a valve for preventing a spill. The culture vessel and the joint are sucked between the first elastic seal and the second elastic seal, thereby forming an integral seeding device.
US08652832B2	Automated analyzer The automatic analyzer repeatedly performs a first processing operation for creating a pretreated specimen with a pretreatment solution in a first reaction cell. The analyzer also repeatedly performs a second processing operation for creating a reacted specimen by reacting the pretreated specimen with a reagent in a second reaction cell. In a first control operation, a turntable is rotated through a first angle in a first direction and halted. In a second control operation, the turntable is rotated through a second angle in a second direction and halted. The second reaction cell is spaced by a second angle in a first direction from the first reaction cell. The turntable is so rotated that the first and second reaction cells are halted at least in first, second, and third positions.
US08652827B2	Radiosynthesis as an alternative energy utilization process in melanized organisms and uses thereof This present invention provides methods of enhancing the growth of a microorganism or plant by increasing its melanin content and exposing it to radiation, and methods of using melanized microorganisms to contain or exclude radiation.
US08652826B2	Marine bacterial strains of cycloclasticus and marinobacter for degradation of high-molecular-weight polycyclic aromatic hydrocarbons A composite marine bacterial liquid for the synergic degradation of high-molecular-weight polycyclic aromatic hydrocarbons (HMW PAHs) and the preparation method thereof. The composite marine bacterial liquid is generated by mixing the fermented culture liquid of a stain of Cycloclasticus sp. PY97M and a stain of Marinobacter sp. D15-8W, the cell concentration of each is 107-109 CFU/mL. The preparation method includes: inoculating the seed liquid of Cycloclasticus strains and Marinobacter strains individually into the sodium acetate medium or M8 medium, fermenting under the condition of defoaming by flowing addition of defoamer, and mixing the fermented cultures to obtain the composite marine bacterial liquid, then preparing a 5-fold concentrated liquid by centrifuging and storing at 4° C.
US08652822B2	Refrigerator-temperature stable influenza vaccine compositions Methods and compositions for the optimization and production of refrigerator-temperature stable virus, e.g., influenza, compositions are provided. Formulations and immunogenic compositions comprising refrigerator-temperature stable virus compositions are provided.
US08652821B2	Stabilized protease-containing solutions for purifying RNA-free DNA The present invention provides compositions and methods for purifying RNA-free DNA from a sample.
US08652818B2	Method for extracting protein from a fermentation product A method of producing bioproducts from a feedstock in a system configured to produce ethanol and distillers grains from a fermentation product is disclosed. A system configured to process feedstock into a fermentation product and bioproducts including ethanol and meal is disclosed. A bioproduct produced from a fermentation product produced from a feedstock in a biorefining system is disclosed.
US08652817B2	Recombinant host cells and media for ethanol production Disclosed are recombinant host cells suitable for degrading an oligosaccharide that have been optimized for growth and production of high yields of ethanol, and methods of making and using these cells. The invention further provides minimal media comprising urea-like compounds for economical production of ethanol by recombinant microorganisms. Recombinant host cells in accordance with the invention are modified by gene mutation to eliminate genes responsible for the production of unwanted products other than ethanol, thereby increasing the yield of ethanol produced from the oligosaccharides, relative to unmutated parent strains. The new and improved strains of recombinant bacteria are capable of superior ethanol productivity and yield when grown under conditions suitable for fermentation in minimal growth media containing inexpensive reagents. Systems optimized for ethanol production combine a selected optimized minimal medium with a recombinant host cell optimized for use in the selected medium. Preferred systems are suitable for efficient ethanol production by simultaneous saccharification and fermentation (SSF) using lignocellulose as an oligosaccharide source. The invention also provides novel isolated polynucleotide sequences, polypeptide sequences, vectors and antibodies.
US08652813B2	Recombinant Thermoascus aurantiacus β-glucosidase variants The present invention provides compositions and methods for the expression of recombinant β-glucosidase variants, as well as their use in the production of fermentable sugars from cellulosic biomass.
US08652808B2	Method for the production of fucosyllactose in bacterial cells The present invention relates to a cell to be stably cultured in a medium, which cell is adjusted for the production of oligosaccharides, the cell being transformed to comprise at least one nucleic acid sequence coding for an enzyme involved in oligosaccharide synthesis. In addition the cell is transformed to comprise at least one nucleic acid sequence coding for a protein of the sugar efflux transporter family, a functional homolog or derivative thereof. Further, the invention concerns a method for the production of oligosaccharides involving above cell.
US08652807B2	Lentiviral vectors for the preparation of immunotherapeutical compositions The invention relates to an immunogenic composition comprising a recombinant vector characterized in that it comprises a polynucleotide comprising the cis-acting central initiation region (cPPT) and the cis-acting termination region (CTS), these regions being of retroviral or retroviral-like origin, said vector comprising in addition a defined nucleotide sequence (transgene or sequence of interest) and regulatory signals of retrotranscription, expression and encapsidation of retroviral or retroviral-like origin, wherein the composition is capable of inducing or of stimulating a cell-mediated response for instance a CTL (Cytotoxic T Lymphocytes) response or a CD4 response, against one or several epitopes encoded by the transgene sequence present in the vector.
US08652806B2	Nucleic acids encoding for antifungal bifunctional molecules for treating fungal infection The present invention is directed to nucleic acids encoding for fusion peptides comprising a fungal targeting agent and a channel-forming domain consisting essentially of amino acids 451-626 of colicin Ia, as well as vectors having the nucleic acids of the invention and host cells having the vectors. The fusion peptides of the peptides of the present invention are particularly useful for the treatment of fungal infections in a wide variety of organisms. The fusion peptides can be prepared from the nucleic acids, such as when a vector having the nucleic acid is included in a host cell.
US08652805B2	Trapping molecular segments in nano-gaps A molecule trapping method includes forming a fluid bridge between a first reservoir and a second reservoir, translocating a molecule from the first reservoir to the second reservoir through the fluid bridge, detecting when a segment of the molecule is in the fluid bridge, breaking the fluid bridge and forming an a gap between the first and the second reservoirs, thereby trapping a segment of the molecule in the gap and making measurements on the segment of the molecule.
US08652802B2	Sampling device A portable sampling device (2) for obtaining a biological sample from a subject comprises sample collection means (8) for excising a biological sample (14) from a subject, and sample containment means (6) for containing excised sample (14) and sample preservative (12) for preserving excised sample. The sample collection means (8) includes sample cutting means (18) adapted, inuse, to cut into the subject and release the biological sample therefrom.
US08652801B2	Hydrophilic IR transparent membrane, spectroscopic sample holder comprising same and method of using same The present invention features hydrophilic IR-transparent porous membranes, particularly hydrophilic IR-transparent porous polyethylene membranes and methods of preparing the hydrophilic membranes by treatment of hydrophobic IR-transparent porous membranes with plasma. The present invention further features spectroscopic sample holders which incorporate the hydrophilic IR-transparent porous membranes and methods of identifying bacteria and other microorganisms in samples by infrared spectroscopy.
US08652798B2	Analysis of ex vivo cells for disease state detection and therapeutic agent selection and monitoring Described herein is the analysis of nanomechanical characteristics of cells. In particular, changes in certain local nanomechanical characteristics of ex vivo human cells can correlate with presence of a human disease, such as cancer, as well as a particular stage of progression of the disease. Also, for human patients that are administered with a therapeutic agent, changes in local nanomechanical characteristics of ex vivo cells collected from the patients can correlate with effectiveness of the therapeutic agent in terms of impeding or reversing progression of the disease. By exploiting this correlation, systems and related methods can be advantageously implemented for disease state detection and therapeutic agent selection and monitoring.
US08652795B2	Mutant lactate oxidase with increased stability and product, methods and uses involving the same The present disclosure relates to a mutant lactate oxidase having increased stability, a nucleic acid encoding the mutant lactate oxidase, an expression vector comprising the nucleic acid, a host cell comprising the nucleic acid or the expression vector, a method of determining lactate in a sample, the use of the mutant lactate oxidase for determining lactate, a device for determining lactate in a sample using the mutant lactate oxidase and a kit for determining lactate comprising the mutant lactate oxidase.
US08652793B2	Solid phase-bound elastase-binding assay for the measurement of alpha1-antitrypsin activity The present invention relates to a method for the measurement of active alpha1-proteinase inhibitor (A1PI) in a sample, comprising the steps of binding elastase to a solid support, letting the A1PI contained in the sample bind to the solid phase-bound elastase, and detecting solid phase-bound A1PI with a detection reagent.
US08652787B2	Use of ERBB4 as a prognostic and therapeutic marker for melanoma It is disclosed herein that members of the protein tyrosine kinase (PTK) family are highly mutated in patients with melanoma. Described herein are novel somatic mutations in the ERBB4 gene that result in increased kinase activity, transformation ability and anchorage-independent growth. These ERBB4 mutations contribute to the tumorogenicity of melanoma. Thus, provided herein is a method of predicting the prognosis of a patient with melanoma by detecting the presence or absence of a mutation in the ERBB4 gene. In some examples, the ERBB4 mutation is selected from G949A, G1354A, G1624A, C1630T, G1687A, G2506A and G2614A (numbering based on SEQ ID NO: 1). Also provided are methods of selecting a patient as a candidate for treatment with an ERBB4 and/or PI3K/AKT pathway inhibitor, and a method of identifying a therapeutic agent for the treatment of a subject diagnosed with melanoma. Oligonucleotides that specifically hybridize with an ERBB4 nucleic acid molecule comprising a novel mutation, and arrays comprising such oligonucleotides, are also provided.
US08652780B2	Restriction endonuclease enhanced polymorphic sequence detection Provided is an improved method for the detection of specific polymorphic alleles in a mixed DNA population. The method comprises enriching the relative percentage of a given polymorphic allele that is exponentially amplifiable by PCR. Also provided are methods for selectively enriching target nucleic acid, for example, fetal nucleic acid in a maternal sample. In the case of detecting fetal nucleic acid in a maternal sample, a restriction enzyme is introduced that can discriminate between the alleles of a polymorphic site. Preferably, the maternal allele is digested and nucleic acid comprising the paternal allele is relatively enriched.
US08652779B2	Nanopore sequencing using charge blockade labels The invention relates to devices and methods for nanopore sequencing. The invention includes compositions and methods of nucleic acid sequencing using a single polymerase enzyme complex comprising a polymerase enzyme and a template nucleic acid attached proximal to a nanopore, and nucleotide analogs in solution comprising charge blockade label that are attached to the polyphosphate portion of the nucleotide analog such that the charge blockade labels are cleaved when the nucleotide analog is incorporated into a growing nucleic acid and the charge blockade label is detected by the nanopore to determine the presence and identity of the incorporated nucleotide and thereby determine the sequence of a template nucleic acid.
US08652772B2	Stable recombinant yeasts for fermenting xylose to ethanol Described are recombinant yeast which ferment xylose to ethanol and which maintain their ability to do so when cultured for numerous generations in non-selective media. The preferred yeast contain multiple copies of integrated genes encoding xylose reductase, xylitol dehydrogenase, and xylulokinase fused to promoters which are non-glucose inhibited and which do not require xylose for induction. Also described are preferred methods for integrating multiple copies of exogenous DNA into host cells by transforming cells with replicative/integrative vectors, and then replicating the cells a number of times under selective pressure to promote retention of the vector in subsequent generations. The replicated vectors thus serve to integrate multiple copies of the exogenous DNA into the host cells throughout the replication/selection phase. Thereafter the selective pressure can be removed to promote loss of the vector in subsequent generations, leaving stable integrants of the exogenous DNA.
US08652771B2	Measurement of succinate in urine samples as a biomarker of kidney damage in diabetic subjects The present invention relates in general to the discovery of urinary succinate as a novel biomarker of kidney disease. More specifically, the invention provides for the measurement of succinate in urine samples that has great potential for the easy and early diagnosis of kidney damage and would allow early prediction of kidney disease and therapeutic intervention.
US08652767B2	Liquid ejection head and process for producing the same Provided is a process for producing a liquid ejection head including an ejection orifice member having a plurality of ejection orifices for ejecting liquid provided along an arrangement direction, the process including preparing a substrate provided with a resin layer which contains a photocurable resin; carrying out a first exposure treatment and a second exposure treatment which are each of an exposure treatment of subjecting the resin layer to exposure; and forming the ejection orifices of the resin layer subjected to the first exposure treatment and the second exposure treatment. An inclination angle of a side wall of the ejection orifices formed by the first exposure treatment with respect to the substrate differs from an inclination angle of a side wall of the ejection orifices formed by the second exposure treatment with respect to the substrate.
US08652766B2	Manufacturing method of display device An organic passivation film having a high transmittance and capable of setting a taper angle of a through hole within a predetermined range in a liquid crystal display device. A pixel electrode and a source electrode of a TFT are connected by way of a through hole formed in an organic passivation film. The organic passivation film having high productivity, high transmittance, and a predetermined taper angle θ of a through hole can be formed by using a chemical amplification photosensitive resin composition comprising, as a base material, an acrylic resin having a molecular weight of 4,000 to 20,000 and containing 1 to 6 wt % of a photoacid generator as the material for the organic passivation film, performing exposure and development for forming a through hole, and then performing post exposure, prebaking, and baking under appropriate conditions.
US08652761B2	Photosensitive resin laminate and thermal processing of the same A method of thermally developing photocurable printing blank to produce a relief pattern comprising a plurality of relief dots. The photocurable printing blank comprises a backing layer having at least one photocurable layer disposed thereon and a laser ablatable mask layer disposed on top of the at least one photocurable layer. The method includes the steps of (1) imaging the at least one photocurable layer by ablating portions of the laser ablatable mask layer; (2) laminating an oxygen barrier membrane to a top of the laser ablated mask layer; (3) exposing the printing blank to actinic radiation through the oxygen barrier membrane and mask layer to actinic radiation, thereby creating the relief pattern; (4) removing the oxygen barrier membrane; and (5) thermally developing the printing blank to remove the laser ablated mask layer and uncured portions of the photocurable layer and reveal the relief pattern. The presence of the oxygen harrier membrane produces printing dots having desired characteristics.
US08652760B2	Printing plate precursor for laser engraving, printing plate, and method for producing printing plate A printing plate precursor for laser engraving, including a relief forming layer including a cured resin material formed by thermally crosslinking a resin composition including at least (A) non-porous inorganic particles, (B) a binder polymer having a glass transition temperature (Tg) of 20° C. or higher, and (C) a crosslinking agent.
US08652759B2	Processing of lithographic printing plates with a developer solution containing a hydrophilic polymer A method is described for producing an imaged lithographic printing plate, wherein the developer comprises a hydrophilic polymer which comprises (m1) primary, secondary and/or tertiary amino groups, and (m2) acid groups selected from —COOH, —SO3H, —PO2H and —PO3H2, and (m3) optionally alkylene oxide units —(CHR1—CH2—O)p—, wherein R1 is H or —CH3 and p is an integer from 1 to 50.
US08652757B2	Method for forming resist underlayer film, patterning process using the same, and composition for the resist underlayer film A method for forming a resist underlayer film of a multilayer resist film having at least three layers used in a lithography, includes a step of coating a composition for resist underlayer film containing a novolak resin represented by the following general formula (1) obtained by treating a compound having a bisnaphthol group on a substrate; and a step of curing the coated composition for the resist underlayer film by a heat treatment at a temperature above 300° C. and 600° C. or lower for 10 to 600 seconds. A method for forming a resist underlayer film, and a patterning process using the method to form a resist underlayer film in a multilayer resist film having at least three layers used in a lithography, gives a resist underlayer film having a lowered reflectance, a high etching resistance, and a high heat and solvent resistances, especially without wiggling during substrate etching.
US08652753B2	Resist composition and method for producing resist pattern A resist composition having; a resin having a structural unit represented by the formula (I), a resin being insoluble or poorly soluble in alkali aqueous solution, but becoming soluble in an alkali aqueous solution by the action of an acid and not including the structural unit represented by the formula (I), an acid generator, and a salt having an anion represented by the formula (IA). wherein R1, A1, A13, X12, A14, R1A and R2A are defined in the specification.
US08652751B2	Resist composition, method for forming resist pattern, and method for producing electronic device A resist composition, which contains: a silicon compound having at least an alkyl-soluble group which may be substituted with a substituent; and a resin having an alkali-soluble group which may be substituted with an acid labile group, wherein the resist composition is designed to be subjected to immersion lithography.
US08652746B2	Manufacturing method for polyester particle dispersion liquid The present invention relates to a process for producing a dispersion of polyester particles which includes the step of emulsifying mixed polyester containing (1) an amorphous polyester containing a constitutional unit derived from a trivalent or higher-valent carboxylic acid in an amount of from 2.0 to 12.0 mol % on the basis of whole constitutional units of the whole amorphous polyester and (2) a crystalline polyester, in an aqueous medium in a single vessel, or the step of mixing the mixed polyester with an organic solvent and then adding the aqueous medium to the resulting mixture to emulsify the mixed polyester in a single vessel. The present invention also relates to a dispersion of polyester particles produced by the above production process, as well as a toner for electrophotography which is produced by subjecting the dispersion of the polyester particles to aggregation and coalescence and is excellent in both of a low-temperature fusing property and an anti-hot offset property, and a process for producing the toner.
US08652744B2	Method for manufacturing toner and toner A method for producing toner particles by ejecting a liquid from at least one ejection hole to form the liquid into liquid droplets, and solidifying the liquid droplets to produce toner particles. The ejecting is accomplished by applying a vibration to the liquid in a liquid column resonance-generating liquid chamber in which an ejection hole is formed to form a standing wave through liquid column resonance, and ejecting the liquid from the ejection hole which is formed in a region corresponding to an antinode of the standing wave to thereby form the liquid into the liquid droplets. Toner produced by the method.
US08652742B2	Method for producing print having foil image and toner image Provided is a method for producing a print having a toner image and a foil image, the method containing the steps of forming a foil transferring toner image with a foil transferring toner on an image supporting substrate produced; heating and pressing by laminating the foil transferring toner image onto a transferring foil layer of a transferring foil sheet which is composed of the transferring foil layer and a base film; forming a foil image having the transferring foil layer on the foil transferring toner image by peeling off the base film after cooling the foil transferring toner image with the transferring foil layer; and forming a toner image with an image forming toner on the image supporting substrate having the foil transferring image, wherein the foil transferring toner contains a resin produced by a vinyl monomer represented by Formula (1) and a polyvalent metal compound:
US08652738B2	Contact developing method, image forming apparatus, and process cartridge A contact developing method including supplying a two-component developer to an electrostatic latent image on a rotating image bearing member by rotating a developing sleeve and a rotatable magnet having multiple magnetic poles provided inside the developing sleeve, to develop the electrostatic latent image into a toner image. The developing sleeve and the image bearing member rotate in the same direction while facing each other. The two-component developer comprises a non-magnetic toner and a carrier. The carrier comprises a magnetic core particle and a resin layer covering the magnetic core particle. The resin layer comprises a conductive particle and a resin. The conductive particle comprises an alumina-based material and a conductive layer covering the alumina-based material. The resin is obtained by heating a copolymer comprising a monomer A unit and a monomer B unit.
US08652737B2	Toner and image forming process A toner which has i) toner base particles containing at least a binder resin and a colorant and ii) a fatty acid metal salt composition as an external additive. The fatty acid metal salt composition contains a nonionic surface-active agent and a fatty acid metal salt. This toner and an image forming process making use of the toner can keep the toner from adhering to a toner carrying member throughout running, promise a stable chargeability of the toner and can keep any deterioration of halftone image quality from being caused by excess charging of the toner and any image fog from being caused by insufficient charging of the toner.
US08652736B2	Electrophotographic developer carrier core material, electrophotographic developer carrier, methods of manufacturing the same, and electrophotographic developer The present invention provides a carrier core material for use in the production of an electrophotographic developer which, even when applied, for example, to MFPs (multifunction printers), can realize stable, high-quality and high-speed development, and has a prolonged replacing life of magnetic carriers, and a method of manufacturing the same, a magnetic carrier including the carrier core material, and an electrophotographic developer manufactured from the magnetic carrier. An electrophotographic development carrier is prepared by adding resin particles, a binder, a dispersant, a wetting agent, and water to a raw material powder, wet pulverizing the mixture, drying the pulverized product to give granulated powder, calcinatng the granulated powder, and then sintering the granulated powder to prepare a carrier core material having an internally hollow structure, and coating the carrier core material with a resin. An electrophotographic developer is manufactured by mixing the electrophotographic development carrier with a toner.
US08652734B2	Low density toner for optimal image quality and performance latitude A toner composition includes toner particles including an average diameter ranging from about 3 μm to about 10 μm, an average particle density of about 1.4 g/cm3 or less, and for a given particle size configured to have a decreased mass and reduced particle momentum. The toner particle can include one of a solid core and a solid outer shell, a porous core and a porous outer shell, and a solid outer shell with a hollow core. The porous and solid cores can include a low density material.
US08652732B2	Tunable gloss toners The present disclosure provides toners having a tunable gloss level, electrophotographic apparatus for suing such toners as well as processes for making such toners.
US08652729B2	Toner for electrostatic image development, developer for electrostatic image development, developer cartridge, process cartridge, and image-forming apparatus, and image-forming method A toner for electrostatic image development including: a toner particle containing a polyester resin and a coloring agent; and an uncolored particle containing a polyester resin and not containing a coloring agent, wherein shape factor SF1 of the uncolored particles is 110 or less, and the number of the uncolored particles is 50 or less based on 5,000 toner particles.
US08652726B2	Toner for developing electrostatic image, method of producing toner, cartridge, image forming method, and image forming apparatus A toner for developing an electrostatic image, includes: colored particles containing a colorant and a binder resin, and two or more kinds of inorganic particles that are externally added to a surface of the colored particles, in which the two or more kinds of inorganic particles contain titanium-containing particles and silica-containing particles, an exposure ratio of the surface of the colored particles is about 25% or less, and a ratio of the silica-containing particles that are in contact with the colored particles is about 10% by number or less.
US08652723B2	Toner particles comprising colorant-polyesters A toner composition including a colorant-polyester polymer having at least one colorant and at least one polyester resin, an optional non-colorant polyester polymer, an optional additional colorant, an optional wax, and an optional additive, where the colorant is covalently linked to some or all of the polyester resin and the polyester resin is obtained by polymerizing a lactone using an enzyme catalyst. Methods for preparing a toner composition including an emulsion aggregation process.
US08652722B2	Electrostatic charge image developing toner, electrostatic charging image developer, toner cartridge, process cartridge, method of producing electrostatic charge image developing toner, and image forming apparatus An electrostatic charge image developing toner contains a binder resin, a release agent, a black colorant, a methylglycine diacetate, and an aluminum element, the content of the methylglycine diacetate is in the range of from 5 ppm to 500 ppm, and the content of the aluminum element is in the range of from 0.07 atomic % to 0.18 atomic % in total element analysis using fluorescent X-rays.
US08652717B2	Image bearing member and image forming method, image forming apparatus, and process cartridge using the same An image bearing member having an electroconductive substrate, a photosensitive layer overlying the electroconductive layer, and a cross-linked surface layer overlying the photosensitive layer, which contains a cross-linked polymer and a first compound consisting essentially of a nitrogen atom and a phenyl group, biphenyl group, and condensed polycyclic hydrocarbon group, or a second compound consisting essentially of a nitrogen atom and hydrogen atoms, halogen atoms, alkyl groups, alkoxy groups, or aryl groups, substituted or non-substituted alkyl groups, substituted or non-substituted alkoxy groups, substituted or non-substituted aralkyl groups, substituted or non-substituted aryl group, substituted or non-substituted alkylene groups, cyano groups, nitro groups, or —OCO═CH2R16, in which R16 represents a hydrogen atom, a substituted or non-substituted alkyl group, a substituted or non-substituted alkoxy group, or a substituted or non-substituted aryl group.
US08652713B2	Furan derivative and electrophotographic photoconductor A furan derivative represented by the following General Formula (1): where Ar1 and Ar2 each independently represent an aryl group which may have a substituent, and R1 represents a C1-C6 alkylene group.
US08652709B2	Method of sealing a bipolar plate supported solid oxide fuel cell with a sealed anode compartment Methods of sealing a bipolar plate supported solid oxide fuel cell with a sealed anode compartment are provided. The solid oxide fuel cell includes a cathode, an electrolyte, and an anode, which are supported on a metallic bipolar plate assembly including gas flow fields and the gas impermeable bipolar plate. The electrolyte and anode are sealed into an anode compartment with a metal perimeter seal. An improved method of sealing is provided by extending the metal seal around the entire perimeter of the cell between an electrolyte and the bipolar plate to form the anode compartment. During a single-step high temperature sintering process the metal seal bonds to the edges of the electrolyte and anode layers, the metal foam flow field and the bipolar plate to form a gastight containment.
US08652708B2	Fluid flow plate with a supporting frame for a fuel cell A fluid flow plate of a fuel cell includes a main body and a supporting frame. The main body includes a plurality of fluid channels and an opening, wherein the fluid channels converge at the opening. The supporting frame, mounted on the periphery of the opening, is annular shaped and frames the fluid channels. The supporting frame includes a pair of supporting walls respectively disposed on two sides of the fluid channels.
US08652705B2	Solid polymer electrolyte and process for making same A solid polymer electrolyte membrane having a first surface and a second surface opposite the first surface, where the solid polymer electrolyte membrane has a failure force greater than about 115 grams and comprises a composite membrane consisting essentially of (a) at least one expanded PTFE membrane having a porous microstructure of polymeric fibrils, and (b) at least one ion exchange material impregnated throughout the porous microstructure of the expanded PTFE membrane so as to render an interior volume of the expanded PTFE membrane substantially occlusive; (c) at least one substantially occlusive, electronically insulating first composite layer interposed between the expanded PTFE membrane and the first surface, the first composite layer comprising a plurality of first carbon particles supporting a catalyst comprising platinum and an ion exchange material.
US08652704B2	Direct alcohol fuel cell with cathode catalyst layer containing silver and method for producing the same The direct alcohol fuel cell of the present invention is a direct alcohol fuel cell comprising an anode 20 having an anode catalyst layer 2, a cathode 30 having a cathode catalyst layer 3, and a solid polymer electrolyte membrane 1 arranged between the anode 20 and cathode 30, the direct alcohol fuel cell generating electricity by supplying the anode 20 with alcohol and water; wherein the cathode catalyst layer 3 contains a metal complex and/or a metal complex fired product formed by firing the metal complex as a catalyst.
US08652702B2	Fuel cell systems and related arrangements for limiting relative motion between fuel cells Fuel cell systems (10) and related methods for limiting fuel cell slippage are provided. A stacked plurality of adjacent fuel cells (14) collectively forming a fuel cell stack (12). The fuel cells each include a pair of first and second plates (30, 30′, 30″; 32, 32′, 32″) at respective opposite ends thereof. A first fuel cell has a first plate (30, 30′, 30″) in engagement with a second plate (32, 32′, 32″) of a second fuel cell adjacent to the first fuel cell. A slip mitigation arrangement (50, 50′, 50″) between at least one of the pairs of the first and second fuel cells comprises first and second seats (62, 62′, 62″; 64, 64′, 64″) recessed in the engagement surfaces of the first and second conductive plates respectively, and a key member (60, 60′, 60″) having opposite ends seated in the first and the second recessed seats such that relative movement between the first and the second fuel cells is limited.
US08652700B2	Fuel cell A fuel cell comprises an electrolyte electrode assembly which includes an anode electrode, a cathode electrode, and an electrolyte; a separator which includes a sandwiching portion; a fuel gas channel which is formed at a first surface of the sandwiching portion, and is covered by the anode electrode; fuel gas outlets which are formed around the fuel gas channel; an oxygen-containing gas channel which is formed at a second surface of the sandwiching portion, and is covered by the cathode electrode; and oxygen-containing gas outlets which are formed around the oxygen-containing gas channel, in which the oxygen-containing gas outlets are formed at phases different from phases of the fuel gas outlets in a thickness direction of the separator.
US08652691B1	Pre-oxidation of metallic interconnects A method of making a metal interconnect for an electrolytic cell stack includes oxidizing the metal interconnect prior to providing the oxidized metal interconnect into the electrolytic cell stack. A pre-oxidized metal interconnect for an electrolytic cell stack would not substantially further oxidize upon exposure to a subsequent oxidizing ambient at a temperature of at least 900° C. prior to or after being provided into the electrolytic cell stack.
US08652690B2	Lithium primary battery Reducing an initial voltage degrades intermediate-load discharge performance.In a lithium primary battery containing iron disulfide as a positive electrode active material, a solvent of a nonaqueous electrolyte contains DIOX and DME as main components, and further contains THF. Moreover, the content of THF is 20 vol. % or lower.
US08652689B2	Energy storage device and system An energy storage device includes a housing having an interior surface defining a volume and a plurality of solid electrolyte elements disposed in the volume. Each solid electrolyte element has a first surface that defines at least a portion of a first, cathodic chamber, and a second surface that defines a second, anodic chamber. A plurality of individual anodic chambers are thus provided, at least one of which is evacuated below atmospheric pressure. A majority of anodic chambers can be spaced from one another in a manner that provides a substantially uniform reaction rate throughout the cathodic chamber. The housing and the plurality of solid electrolyte elements together may be configured to define a second volume devoid of solid electrolyte elements and that is sufficient in size to accommodate a desired number of solid electrolyte elements and to provide an accessible cathodic chamber filling point and that is further sufficient in size to alter the volume of the cathodic chamber with respect to the volume of the plurality of anodic chambers to achieve a desired volumetric ratio between the cathodic and anodic chambers.
US08652688B2	Alginate-containing compositions for use in battery applications A silicon-based anode comprises an alginate-containing binder. The many carboxy groups of alginate bind to a surface of silicon, creating strong, rigid hydrogen bonds that withstand battery cycling. The alginate-containing binder provides good performance to the anode by (1) improving the capacity of the anode in comparison to other commercially-available binders, (2) improving Columbonic efficiency during charging and discharging cycles, and (3) improving stability during charging and discharging cycles.
US08652686B2	Substantially impervious lithium super ion conducting membranes A composite solid electrolyte includes a monolithic solid electrolyte base component that is a continuous matrix of an inorganic active metal ion conductor and a filler component used to eliminate through porosity in the solid electrolyte. In this way a solid electrolyte produced by any process that yields residual through porosity can be modified by the incorporation of a filler to form a substantially impervious composite solid electrolyte and eliminate through porosity in the base component. Methods of making the composites are also disclosed. The composites are generally useful in electrochemical cell structures such as battery cells and in particular protected active metal anodes, particularly lithium anodes, that are protected with a protective membrane architecture incorporating the composite solid electrolyte. The protective architecture prevents the active metal of the anode from deleterious reaction with the environment on the other (cathode) side of the architecture, which may include aqueous, air and organic liquid electrolytes and/or electrochemically active materials.
US08652685B2	Method of making an electrochemical cell with a catalytic electrode including manganese dioxide The invention is a process for making an electrochemical cell with a catalytic electrode including a catalyst made by a solution precipitation process via an oxidation-reduction reaction between water-soluble oxidizing and reducing agents, at least one of which includes manganese. The reaction is carried out at less than 65° C., preferably with little or no heating. The oxidizing agent does not have a cation that is reduced in the reaction, and the reducing agent does not have an anion that is reduced in the reaction.
US08652677B2	Rechargeable battery for hand-guided electromechanical tools A rechargeable battery (1) for hand-guided electromechanical tools, having a plurality of rechargeable battery cells (10) which are electrically connected to one another by means of electrical cell connectors (110), wherein the electrical cell connectors (110) are fixed to a cell connection frame (120), which is provided on one pole side (19) of the rechargeable battery cells (10), for the purpose of simplified mounting of the electrical cell connectors (110) on the rechargeable battery cells (10). Furthermore, an electromechanical tool, in particular a cordless screwdriver, a drill, a circular saw, a jigsaw, a sander, a garden appliance, having a rechargeable battery (1) according to the invention.
US08652675B2	Cooling structure of lithium ion secondary battery system The present invention relates to a cooling structure of a lithium ion secondary battery system. The cooling structure of a lithium ion secondary battery system according to the present invention provides cooling channels for lithium battery unit cells accommodated by a laterally partitioned arrangement of main frames, each having a heat radiation part and lattice-shaped paths, and partitioning frames, and allows air, blown by a cooling fan, to cool the lithium battery unit cells while passing through the cooling channels and the lattice-shaped paths. Each of the main frames has a pair of passage slots formed in both sides thereof to allow the air blown by the cooling fan to be directly blown to each accommodated lithium battery unit cell, thus forming each secondary cooling channel communicating with the pair of passage slots.
US08652672B2	Large format electrochemical energy storage device housing and module An assembly includes non-load bearing housings, each housing including several cavities. Each cavity includes a stack of freely stacked electrochemical storage cells in the housings. Each electrochemical storage cell includes an anode electrode, a cathode electrode, and a separator located between the anode electrode and the cathode electrode. The assembly is configured such that pressure applied to the assembly is born by the freely stacked electrochemical storage cells.
US08652671B2	Separator for battery, and battery and method for producing battery including the same A separator for a battery includes a porous polymer film having a first surface and a second surface opposite to the first surface, wherein the first surface has openings distributed thereon communicating with pores of the porous polymer film, and the ratio of the total area of the openings to the area of the first surface is 89% or more and 96% or less. The diameters of the openings may be within the range of 0.8 μm or more and 40 μm or less. A region with a predetermined thickness including at least the first surface of the porous polymer film preferably includes at least one selected from the group consisting of polypropylene, and a copolymer of propylene and another copolymerizable monomer.
US08652668B2	Secondary battery; solar power generation system, wind power generation system, and vehicle provided therewith; and method for fabrication of a secondary battery A secondary battery with improved life characteristics is provided. The secondary battery (lithium-ion secondary battery) has: an electrode assembly including positive electrodes and negative electrodes; and a package container for housing the electrode assembly along with non-aqueous electrolyte liquid. The package container includes a package can for housing the electrode assembly and a sealing plate sealing the opening of the package can. On the sealing plate, an elevated portion is formed that projects toward the electrode assembly and has, on the side opposite from the electrode assembly, a cavity portion for storing refill non-aqueous electrolyte liquid. The elevated portion has a hole for feeding the refill non-aqueous electrolyte liquid stored in the cavity portion toward the electrode assembly. The hole is sealed with a sealing stopper formed of a resin material letting the refill non-aqueous electrolyte liquid leak toward the electrode assembly.
US08652667B2	Battery pack A battery pack includes a bare cell; a circuit module on the bare cell and electrically connected to the bare cell; a loop antenna attached to the bare cell and electrically connected to the circuit module; and a PTC device on the loop antenna and electrically connected to the circuit module.
US08652664B2	Method for taking out a sealing plate of a fuel cell and a sealing plate directly used in the method A fuel cell sealing plate taking-out method that may include taking out a sealing plate from a stack of sealing plates one by one while an air layer exists between adjacent sealing plates of the stack of fuel cells. A protrusion may be formed beforehand at one or more surfaces of each sealing plate. Due to the air layer existing between adjacent sealing plates, it may be possible to take out the sealing plate one by one from the stack of sealing plates.
US08652662B2	Battery pack and method of fabricating the same A battery pack comprising a battery cell coupled to a circuit module and a method of fabricating the same are disclosed. A battery pack comprises a battery cell, a circuit module coupled to the battery cell, wherein the circuit module comprises a top surface, a bottom surface, and terminals on the top surface, a lead plate comprising an extension region extending from the bottom surface of the circuit module to a top region of the battery cell to couple the battery cell to the circuit module, and a cover coupled to the circuit module and the battery cell to expose the terminals to an exterior. The lead plate includes at least a first rib protruding upward from the extension region that contacts a top surface of the battery cell.
US08652661B2	Secondary battery with protection circuit module and method of manufacturing the same A secondary battery with a protection circuit module and a manufacturing method thereof are disclosed. The secondary battery includes a bare cell, and a protection circuit board including a circuit board and a coupling member positioned at least one side in the longitudinal direction of the circuit board to couple the circuit board to the bare cell. The coupling member includes a coupler fixed to the circuit board, and first and second supports respectively extending from the coupler and spaced apart from each other in the longitudinal direction of the circuit board.
US08652660B2	Glass substrate for magnetic recording medium and its use An aspect of the present invention relates to a glass substrate for a magnetic recording medium, which is comprised of glass with a glass transition temperature of equal to or greater than 600° C., an average coefficient of linear expansion at 100 to 300° C. of equal to or greater than 70×10−7/° C., a Young's modulus of equal to or greater than 81 GPa, a specific modulus of elasticity of equal to or greater than 30 MNm/kg, and a fracture toughness value of equal to or greater than 0.9 MPa·m1/2.
US08652658B2	C-plane sapphire method and apparatus A method and apparatus for the production of C-plane single crystal sapphire is disclosed. The method and apparatus may use edge defined film-fed growth techniques for the production of single crystal material exhibiting low polycrystallinity and/or low dislocation density.
US08652655B2	Electroactive materials A compound having Formula I, Formula II, or Formula III: Ar1 may independently be phenylene, substituted phenylene, naphthylene, or substituted naphthylene. Ar2 is the same or different at each occurrence and is an aryl group. M is the same or different at each occurrence and is a conjugated moiety. T1 and T2 are independently the same or different at each occurrence and are conjugated moieties which are connected in a non-planar configuration.
US08652650B2	Platinum-modified nickel-based superalloys, methods of repairing turbine engine components, and turbine engine components Platinum-modified nickel-based superalloys and turbine engine components are provided. The platinum-modified nickel-based superalloy includes, by weight, aluminum, in a range of about 7.8 percent to about 8.2 percent, tantalum, in a range of about 5.0 percent to about 6.0 percent, rhenium, in a range of about 1.6 percent to about 2.0 percent, platinum, in a range of about 0.8 percent to about 1.4 percent, hafnium, in a range of about 0.20 percent to about 0.40 percent, silicon, in a range of about 0.30 percent to about 0.60 percent, about 0.02 percent carbon, about 0.01 percent boron, and a balance of nickel. The platinum-modified a nickel-based superalloy may also include, by weight, chromium in a range of about 4.0 percent to about 5.0 percent.
US08652645B2	Osteosynthesis with nano-silver The present invention relates generally to an antibacterial coating which is composed of silver, to medical tools and to implants comprising such a coating and to a method as well to an apparatus for the production of such a coating. The medical tools or the dental or orthopaedic implant comprises a metal or metal alloy having a treated surface wherein the treated surface is at least partially converted to an oxide film by plasma electrolytic oxidation using a colloid-dispersed system and wherein the converted surface is partially covered by islands formed by colloid-dispersed silver-particles of the colloid-dispersed system. An Ag—TiO2 coating shows excellent properties in terms of antibacterial efficacy (even against multi-resistant strains), adhesion and biocompatibility. The life-time of an implant in a human body is increased. The antibacterial coating can be used in the field of traumatology, orthopaedic, osteosynthesis and/or endoprothesis, especially where high infection risk exists.
US08652642B2	Biaxially oriented polyester film The present invention provides a polyester film which is excellent in hydrolysis resistance of a base film, is hardly deteriorated in adhesion property to various members or top-coating agents, and can suitably used, for example, as a film for a protective member for protecting a back surface of solar cells. The present invention relates to a biaxially oriented polyester film in the form of a laminated film comprising a biaxially oriented polyester base film having a phosphorus element content of 0 to 170 ppm and a terminal carboxylic acid content of not more than 26 equivalents/t, and a coating layer formed on at least one surface of the biaxially oriented polyester base film which comprises a polyurethane having a polycarbonate skeleton or a polyether skeleton and a crosslinking agent, wherein the laminated film has a haze value of not more than 10%.
US08652638B2	Thick thermal barrier coating for superabrasive tool The present disclosure relates to cutting tool edges that include on a rake face a superabrasive layer and a HPHT sintered or HPHT bonded cap layer. The cap layer improves adhesion between the superabrasive layer and an optional coating system for the cutting insert and acts as a thick anti-friction layer and/or a thermal barrier coating.
US08652637B2	Porous particles with non-porous shell The present invention is core-shell polymer particles comprising a common binder polymer for the core and the shell wherein the core has a porosity and the shell is non-porous The particles have a porosity from 10 to 70 percent.
US08652635B2	Insulated wire and resin dispersion An insulated wire, which is coated, on a conductor, with a thin-film insulating layer composed of a resin dispersion, wherein the resin dispersion contains: a polyester-series resin (A) in a continuous phase; and a resin (B) having a functional group capable of reacting with the polyester-series resin, and, if necessary, an olefin-series resin (C), in a dispersed phase; and the resin dispersion.
US08652633B2	Nanoparticulate wax dispersions, process for preparing them and method of hydrophobicizing materials using them The invention provides nanoparticulate wax dispersions comprising wax solids having a solidification point of greater than 40 to 150° C., a process for preparing them, and a method of hydrophobicizing materials produced using fibers, chips or strands comprising or consisting of lignocelluloses and/or celluloses, by contacting them with the wax dispersions.
US08652624B2	Articles and methods of making the same The invention provides an article comprising a first layer and a second layer, and wherein the first layer is formed from a first composition comprising an ethylene/α-olefin/diene interpolymer, an isoprene rubber (synthetic), a natural rubber, a butadiene rubber, a styrene butadiene rubber, a chloroprene rubber, a nitrile rubber, a hydrogenated nitrile rubber, a chlorinated polyethylene, a chlorosulfonated polyethylene, an ethylene/propylene rubber, an ethylene/diene copolymer, a fluoro rubber, a polyurethane, a silicone rubber, or a combination thereof; and wherein the second layer is formed from a second composition comprising a butyl rubber, a halobutyl rubber, polyvinylidene chloride, a brominated polymer derived from a copolymer of isobutylene and p-methyl styrene, a nitrile rubber, a chloroprene rubber, a chlorosulfonated polyethylene, a chlorinated polyethylene, a polyurethane, a fluoro rubber, or a combination thereof.
US08652623B2	Coextruded films with low temperature impact resistance The invention relates to multilayer products comprising a layer (A) and a layer (B), wherein layer (A) contains polyalkyl(alkyl)acrylate and has a layer thickness <25 [mu]m, and layer (B) contains polycarbonate. The total thickness of layers (A) and (B) is 20 to 500 mm.
US08652620B2	Sliding element in an internal combustion engine, in particular a piston ring A sliding element in an internal combustion engine has a coating which has the following layers from the outside inwards: a first carbon-based layer, a second carbon-based layer which is harder and/or has a smaller proportion of hydrogen than the first carbon-based layer, a PVD layer and a bonding layer.
US08652619B2	Diffractive optical element and manufacturing method thereof A diffractive optical element according to the present invention includes: a body 1 being composed of a first optical material containing a first resin, and having a diffraction grating 2 on a surface thereof; and an optical adjustment layer 3 being composed of a second optical material containing a second resin, and provided on the body 1 so as to cover the diffraction grating 2. The first optical material has a refractive index which is smaller than a refractive index of the second optical material; the refractive index of the first optical material has a wavelength dispersion which is greater than a wavelength dispersion of the refractive index of the second optical material; and a difference in solubility parameter between the first resin and the second resin is no less than 0.8 [cal/cm3]1/2 and no more than 2.5 [cal/cm3]1/2.
US08652618B2	Multi-layer film Purpose: The present invention provides a multi-layer film comprising a polyolefin film, an aluminum foil and a polyamide layer which are laminated sequentially, wherein the aluminum foil is adhered directly to the polyolefin film without any anchor coat agent or adhesive and the multi-layer film is excellent in adhesion strength between the polyolefin film and the aluminum foil and in low-temperature resistance.The multi-layer film according to the present invention comprises an aluminum layer (B) subjected to chromium-free chemical conversion treatment, a polyolefin resin film (A) on one side of the layer (B) and a polyamide layer (C) on the other side of the layer (B), wherein the film (A) comprises a layer (A-1) composed of an acid-modified polyethylene resin (α) and a layer (A-2) composed of a crystalline polyethylene resin (β), a temperature at which the acid-modified polyethylene resin (α) has a crystallinity of 60%, Tmα60, is lower than a temperature at which the crystalline polyethylene resin (β) has a crystallinity of 60%, Tmβ60, and the layer (B) is present directly on the layer (A-1).
US08652614B2	Optical element and method for producing the same The present invention relates to an optical element comprising: a optical glass made of a phosphate glass or a fluorophosphate glass; and an optically functional film formed on a surface of the optical glass, wherein the optically functional film comprises two or more layers made of different materials, and the outermost surface layer thereof is made of a material(s) having low reactivity with phosphoric acid.
US08652611B2	Plastic moulded part for a motor vehicle A bionically designed plastic molded part is provided, in particular a carrier, for a motor vehicle, with at least one low-load region for accommodating relatively low loads, which is formed using thin-wall technology, and at least one high-load region for accommodating relatively high loads, which is formed using plastic foam technology and connected to at least one low-load region.
US08652608B2	Floor mat Floor mats for absorbing liquids, comprising a shell having a first and a second portion connected to each other in such a way that the first and the second portions of the shell form a pocket, and an absorbent material, which is a superabsorbent material is arranged in the pocket. The first and/or the second portion of the shell has a length in a range of 200 mm to 1000 mm and a width in a range of 200 mm to 600 mm, wherein the floor mat comprises three sections having a first thickness and two sections having a second thickness, wherein the second thickness is less than the first thickness.
US08652605B2	Method for producing a tubular hollow body, and tubular hollow body The invention relates to a method for producing a tubular hollow body (1) with at least three pipe openings, partly or completely consisting of plastics material. It is provided that a lost core pipe (9), which has a connection opening (13, 14) on each of its ends and has at least one docking opening (11) along its length, is produced, that the core pipe (9) is introduced into a cavity of a mould, with two non-lost core pieces (17, 18) being arranged with one of their ends (3, 4) respectively against the connection openings (13, 14) in a sealing manner and a non-lost core part (19) being arranged with one end against the docking opening (11) in a sealing manner, in that plastics material (25) is then introduced into the mould cavity to encapsulate the core pipe (9), the core pieces (17, 18) and the core part (19) and that, once the plastics material (25) has cured, the core pieces (17, 18) and the core part (19) are withdrawn from the hollow body (1) created. The invention also relates to a corresponding hollow body (1).
US08652602B1	Rotational expansion auxetic structures Auxetic structures exhibiting negative Poisson's ratios are disclosed including planar auxetic structures formed from x-axis and y-axis strands of selected waveforms. Portions of the auxetic structure referred to as unit cells comprise four joints formed by two adjacent x-axis strands overlapping two adjacent y-axis strands display symmetry about x and y axes. Each unit cell comprises four sub-unit cells formed from segments of ½ wavelength of the wave form. The planar auxetic structures may be formed into three-dimensional auxetic structures or cylindrical or spherical auxetic structures.
US08652597B2	High bulk rolled tissue products Spirally wound paper products are disclosed having desirable roll bulk, firmness and softness properties. The rolled products can be made from a multiple ply tissue webs formed according to various processes. Tissue webs having basis weights greater than about 40 grams per square meter were wound into rolls having a Kershaw roll firmness of less than about 9 mm and a roll bulk of greater than about 15 cc/g. Similarly, tissue webs having basis weights less than about 40 grams per square meter were wound into rolls having a Kershaw roll firmness of less than about 9 mm and a roll bulk of greater than about 18 cc/g.
US08652595B2	Recording medium having first set and second set of polymeric beads A recording medium includes a base substrate, a fusible layer including a first set of polymeric beads and a second set of polymeric beads, and an ink receiving layer disposed between the base substrate and the fusible layer. The first set of polymeric beads has an average volume-based particle size less than two microns. The second set of polymeric beads has an average volume-based particle size equal to or greater than five microns. The fusible layer includes a weight percent of the second set of polymeric beads of at least three percent.
US08652591B2	Retardation film, polarizing plate using same, and liquid crystal display device The purpose of the present invention is to provide: a retardation film which uses a low-substituted cellulose ester and has improved retardation after saponification and improved wet heat stability of internal haze; a polarizing plate which uses the retardation film; and a liquid crystal display device. An optical film of the present invention contains a cellulose ester and a compound represented by general formula (1), and is characterized in that the compound has an average degree of substitution within the range of 3.0-6.0 and contains a component having a degree of substitution of 4 or less in an amount of 30-80% by mass (inclusive). (In the formula, R1-R8 each represents a substituted or unsubstituted alkylcarbonyl group or a substituted or unsubstituted allylcarbonyl group, and R1-R8 may be the same as or different from one another.)
US08652590B2	Polarizing plate and liquid crystal display Disclosed is a polarizing plate having low moisture absorption, wherein fading deterioration of a polarizer is improved. A liquid crystal display using the polarizing plate is also disclosed. The polarizing plate is obtained by sandwiching a polarizer composed of a polyvinyl alcohol with an acrylic film (a) having a water vapor permeability of 100-500 g/m2·24 hr and a cellulose ester film (b1) containing no phosphate plasticizer or a cellulose ester film (b2) containing a phosphate plasticizer and an acid scavenger. The polarizing plate is arranged on at least one side of a liquid crystal cell, with the cellulose ester film (b1) or (B2) being on the liquid crystal cell side.
US08652588B2	Method of coating a surface of an article against aquatic bio fouling The invention relates to a method and apparatus for the application of a thin film coating of material onto a surface of an article which is to be exposed to aqueous conditions such as when in the sea or rivers. The invention allows for the formation of a coating which is resistant to fouling and which coating can be formed of materials which have significantly less adverse effect on the quality of the water in which the article is placed in comparison to conventional coating types.
US08652587B2	Method and apparatus for forming film This invention adopts plasma-enhanced chemical vapor deposition using the apparatus including a chamber, a pair of rotary electrode reels including a feed-out reel and a take-up reel, a plasma source, a material gas supplier, and an exhaust unit, and includes applying a negative voltage applied to the rotary electrode reels from the plasma source while a conductive substrate is fed-out from the feed-out reel and is wound on the take-up reel so that the entire surface of the substrate portion between reels contacts the material gas, whereby plasma sheath is formed along the surface of the substrate portion between reels, and the material gas is activated in the plasma sheath and thus contacts the surface of the substrate, thus forming the film on the surface of the substrate.
US08652583B2	Method for producing a three-dimensionally controlled surface coating in a cavity The cavity has first and second main walls covered by a photoresist. The photoresist is subjected to electronic or electromagnetic radiation of wavelength comprised between 12.5 nm and 15 nm. A first thickness of the photoresist is exposed to form a first area of sacrificial material and a second area of different nature defining the surface coating. The sacrificial material is removed, the surface coating is formed and has a surface against one of the main walls and a free opposite surface. The lateral dimensions of the surface coating are defined in the cavity by the radiation through the first main wall.
US08652578B2	Method of forming a cured coating composition on an automobile component A method of forming a cured coating composition on an automobile component is provided. The method utilizes a coating compound including a radical polymerizable compound and an organoborane initiator and includes the step of applying the coating composition to the automobile component. The organoborane initiator is complexed with a bi-functional noncyclic blocking agent that has a carbon backbone and two organoborane complexing moieties. The two moieties are different from each other and are selected from the group of an amine moiety, a thiol moiety, and a phosphine moiety. In addition, the two moieties are separated from each other by two to four carbon atoms to increase the nucleophilicity of the blocking agent towards the organoborane initiator. The organoborane initiator is decomplexed from the blocking agent thereby forming a radical that is used to polymerize the radical polymerizable compound and cure the coating composition on the automobile component.
US08652571B2	Spin coating method and spin coating apparatus A spin coating apparatus that supplies a coating liquid to a substrate and rotating the substrate to form a coating film, has a holding part that holds the substrate mounted thereon in a horizontal position; a rotationally driving source that rotationally drives the holding part about a rotational axis parallel with the vertical direction, thereby rotating the substrate; and a coating liquid supplying part that supplies the coating liquid to the substrate held by the holding part.
US08652570B2	Process for forming unidirectionally oriented fiber structures A process for forming a unidirectionally oriented fiber structure formed of high tenacity fibers. A plurality of yarns of high tenacity fibers are supplied, with the yarns being unidirectionally oriented. The yarns are coated with a liquid having a viscosity of about 5 to about 600 centipoises and tension is applied to the yarns. The yarns are passed through a fiber spreading device and the yarns are dried. The yarns are reduced in thickness and increased in width after passing through the fiber spreading device, with the fibers forming the yarns being spread apart, thus providing a relatively thin unidirectionally oriented fiber structure.
US08652564B2	Aminated materials for assays Protein binding onto a polymeric surface is enhanced by treating the surface with an amine-bearing polymer like poly(ethylene imine). When used in ELISA, the treated surface improves the performance of the assay.
US08652562B2	Powdery seasoning and method for producing the same A method for producing a powdery seasoning of the present invention includes hydrolyzing a protein material with a liquid koji mold cultured in a medium containing wheat bran which has been ground to pass through a 0.3 mm mesh sieve to prepare a hydrolysate, and spray drying the hydrolysate without removing a solid. According to the method for producing the powdery seasoning of the present invention, provided is a powdery seasoning which is spray-dryable without undergoing any solid removal process such as squeezing or filtering after hydrolysis, and achieves higher storage stability than prior art powdery seasoning prepared from a protein hydrolysate liquid.
US08652560B2	Packaged beverages A non-tea-based, packaged beverage with a green tea extract mixed therein contains the following ingredients (A) and (B):(A) 0.06 to 0.5 wt. % of non-polymer catechins, and(B) 9 to 13.5 mM of citric acid or a salt thereof. Its pH is from 3.4 to 4.2. The non-tea-based, packaged beverage contains catechins at a high concentration, is reduced in bitterness and astringency, is suited for long-term drinking, and is excellent in the stability of bitterness and astringency and also in the feeling as it passes down the throat, and moreover, its color tone remains stable over a long term even when packed in a clear package and stored at high temperatures.
US08652555B2	Distiller grain pellet production methods A method for producing a high density compact livestock feed from a loose granular material may include feeding distiller grain into a loading zone and passing the distiller grain into a heating zoned comprising one or more heaters and a rotating screw. The method further includes rotating the screw to transfer the treated material through the heating zone while increasing the compressive force applied to the treated material. The method may further include pressing the treated material through a compression enclosure that simultaneously applies a transverse force and a parallel force onto the treated material to form a high density compact body. The method may then include a cooling process and an extraction process.
US08652549B2	Method for post-extracting low acyl gellan gum with high solubility The invention relates to a post-extraction process for preparing low acyl gellan gum having high solubility property, the process comprising the following steps: (1) enzyme treatment of fermentation broth; (2) flocculation of fermentation broth; (3) deacylation treatment; (4) clarification treatment of deacylated solution; (5) dehydration treatment of clarified and deacylated gellan gum solution; (6) ion exchange and decoloration treatment; and (7) drying and milling. The process according to the invention produces a product, which has largely improved solubility, largely improved quality, good appearance, high transparence, and high gel strength.
US08652548B2	Fish flavour A process for producing a product having a fish flavor is provided, the process comprising preparing a composition comprising 1-20% w/w water and at least a polyunsaturated fatty acid, incubating the composition at less than 260° C. and at a reaction time sufficient for the fish flavor to develop, and optionally mixing the product with one or more other ingredients. The product obtainable by this process and methods for using the same are also provided.
US08652546B2	Morinda citrifolia based formulations for regulating T cell immunomodulation in neonatal stock animals Both liquid and dry form Morinda citrifolia enhanced animal food products are provided for increasing CD8+ T cell activation in new born animals. Both contain M. citrifolia fruit puree and other M. citrifolia plant products.
US08652545B2	Composition of a liquid dietary supplement to treat symptoms of autism spectrum disorders in children The object of the present invention is to provide an all-natural dietary supplement formulation that may be beneficial to the management of behavioral and neurological symptoms associated with autism spectrum disorders; symptoms that may not be effectively improved by conventional drug treatment and behavioral therapy alone.
US08652542B2	Composition for preventing or treating arteriosclerosis A composition according to the present invention is a composition containing extract of Panax ginseng C.A. Meyer fruit as an active ingredient for preventing or treating artherosclerosis. The extract is confirmed to effectively suppress lesions or generation of a vascular inflammation factor caused by artherosclerosis. Thus, the composition is suitable for use as an active ingredient of the composition for preventing or treating artherosclerosis.
US08652541B2	Pharmaceutical composition and method for reducing weight A method for weight reduction, involving pharmaceutical compositions, particularly homeopathic medicines for weight reduction, including the following components: Adonis vernalis, Calcium carbonicum Hahnemann, Capsicum, Cascara, Fucus vesiculosus, Graphites and Kalium Carbonicum and Phytolacca, as well as a nutritient.
US08652537B2	Herbal drug composition for cartilage protection The present invention relates to a herbal drug composition for cartilage protection comprising plant extracts of Clematis Radix, Trichosanthis Radix, and Prunellae Spica and an optimal content of rosmarinic acid to: (i) alleviate pains; (ii) inhibit the acute/chronic inflammation, platelet/whole blood aggregation, immunocyte (B-lymphcyte and T-lymphcyte) proliferation, inflammation-inducing enzyme activities, and enzyme activities associated with degradation of joint tissue; (iii) scavenge activity of toxic active oxygen radicals; and (iv) further provide excellent cartilage protection activity to be effectively used as an anti-inflammatory agent with analgesic effects, blood circulation enhancer, arthritis therapeutic agent and cartilage protective.
US08652535B2	Formulation of a mixture of free-B-ring flavonoids and flavans for use in the prevention and treatment of cognitive decline and age-related memory impairments The present invention provides a novel method for preventing and treating memory and cognitive impairment resulting from oxidative stress, inflammation and the process of aging, as well as, neurodegenerative conditions. The method is comprised of administering a composition comprising a mixture of Free-B-Ring flavonoids and flavans synthesized and/or isolated from a single plant or multiple plants to a host in need thereof. The present also includes a novel method for simultaneously inhibiting expression of pro-inflammatory cytokines, preventing ROS generation and augmenting anti-oxidant defenses. The activity of this composition is conducive to ultimately preserving cognitive function and providing a level of neuroprotection.
US08652534B2	Compositions and methods for treatment of mammalian skin Compositions useful for treatment of a wide range of skin disorders including: pre-cancerous lesions, keratotic lesions, superficial basal cell carcinomae; squamous cell carcinomae; malignant melanoma, and radiation-induced burns. In some embodiments the treatments comprise contacting human or other mammalian skin with a composition according to the disclosure. In other embodiments, administration of compositions provided is by injection. Some embodiments provide for preventive use of compositions provided towards preventing some forms of skin cancer and skin cancer-related disorders by repeated application to healthy-looking skin. Methods for providing the compositions are disclosed.
US08652529B2	Anti-misuse microparticulate oral pharmaceutical form The present invention relates to solid microparticulate oral pharmaceutical forms whose composition and structure make it possible to avoid misuse of the pharmaceutical active principle they contain. The invention relates to a solid oral pharmaceutical form which is characterized in that it contains anti-misuse means, in that at least part of the active principle it comprises is contained in coated microparticles for modified release of the active principle, and in that the coated microparticles have a coating layer which assures modified release of the active principle and simultaneously imparts crushing resistance to the coated microparticles so as to avoid misuse.
US08652527B1	Extended-release topiramate capsules An extended-release topiramate capsule that includes a capsule shell containing a single population of coated particles; wherein each coated particle includes a core and a coating thereon; wherein each particle core includes a homogeneous mixture comprising topiramate throughout its core; and wherein the coating includes one or more release controlling agent(s).
US08652523B2	Oral pharmaceutical formulation in the form of a plurality of microcapsules for prolonged release of active principle(s) with slow solubility The invention concerns microcapsules with prolonged release of active principles with low solubility, consisting of a core containing the active principle and coated with a polymer layer which controls the release of the active principle. The aim is that said oral microcapsules containing hardly soluble active principles, should have a coating film of sufficient thickness to ensure controlled permeability and should be adapted to industrial reproduction. This is achieved by the inventive microcapsules of mean diameter less than 1000 microns, and whereof the coating film contains a film-forming polymer (P1) insoluble in gastrointestinal tract fluids, a water-soluble polymer (P2), a plasticizer (PL), and optionally a lubricating surfactant (TA). Said microcapsules are characterized in that their coating films represents at least 3% p/p of dry matter, relative to their total weight and their core contains a hardly soluble active principle and a solubilizing agent (polyoxyethylene hydrogenated castor oil) which provides the core wherein it is contained with properties such that the behavior of the exposed core (non-coated) in a given dissolving test (TD), is as follows: release of 80% of active principle in less than two hours. The invention also concerns the use of such microcapsules in galenic formulation.
US08652514B2	Antimicrobial peptides Novel peptides having antimicrobial activity, and compositions containing the same.
US08652513B2	Film-forming starchy composition A film-forming starchy composition for the film-coating of solid forms or the preparation of films. The inventive composition has an amylose content of between 25 and 45%, preferably between 30 and 44% and still more preferably between 35 and 40%, the percentages being expressed by dry weight in relation to the dry weight of starch contained in the composition, and includes at least one stabilized starch. A method for the film-coating of solid forms is disclosed and includes spraying the film-forming composition onto a moving nuclei bed. The film-forming composition is used for the production of films and capsules.
US08652509B2	Method of wound hemostasis using liquid gallium nitrate A pharmaceutical composition and method for topical wound treatment by topical treatment with gallium salts, preferably gallium nitrate. In a preferred embodiment, the gallium nitrate is in an aqueous form without coagulation inhibitors such as citrate. The aqueous gallium salt formulation may be administered by a variety of methods including spraying, topical lotions, topical foams, and/or bandages containing or packaged with breakable ampoules of aqueous gallium salt formulations, and liquid bandage formulations. The aqueous gallium salt formulation may additionally contain other active and inactive ingredients, such as viscosity modifying agents, foaming agents, antiseptics, antibiotics, enzymes, fibrinogen, fibrin, polymers and growth factors.
US08652508B2	Dietary formulations and methods for treatment of inflammation and other disorders Dietary formulations in the form of an oil emulsion providing total enteral or parenteral nutrition, or in the form of food oil suitable for oral administration is provided. The formulations include about 2-60% by calories of a C20 or longer omega-3 fatty acid and about 0.05% to 1% by calories of arachidonic acid, where the formulation provides less than 1% of total calories from linoleic acid and alpha-linolenic acid, and where the fatty acids provide 5-60% of the total calories of said dietary formulation. Methods for treatment of diseases and disorders using the dietary formulations are also provided.
US08652506B2	Bio-degradable block co-polymers for controlled release A block or graft copolymer includes a first block, and a second block different from the first block, wherein the first block is a poly(lactide-glycolide) copolymer. The polymers may be formulated in compositions with drug components for use in coating medical devices such as stents. Different blocks of the block or graft copolymer degrade in the body at different rates. The drug release profile from the coating is a combination the individual release rates of the different blocks and so can be controlled by controlling the selection and relative amounts of the respective blocks.
US08652505B2	Coating for medical implants A medical implant for drug delivery comprising an inner layer of polymer material including a drug dispersed therein and an outer layer which may then mediate the release of the drug in a controllable manner. The outer layer may adhere and/or penetrate the underlying layer and offer a protective coating along with improved mechanical strength along with the ability to hydrate and become permeable to water and allow for drug release.
US08652502B2	Local vascular delivery of trichostatin A alone or in combination with sirolimus to prevent restenosis following vascular injury Medical devices, and in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number of biocompatible materials. Therapeutic drugs, agents or compounds may be mixed with the biocompatible materials and affixed to at least a portion of the medical device. These therapeutic drugs, agents or compounds may also further reduce a biological organism's reaction to the introduction of the medical device to the organism. In addition, these therapeutic drugs, agents and/or compounds may be utilized to promote healing, including the formation of blood clots. Also, the devices may be modified to promote endothelialization. Medical devices include stents, grafts, anastomotic devices, perivascular wraps, sutures and staples. In addition, various polymer combinations may be utilized to control the elution rates of the therapeutic drugs, agents and/or compounds from the implantable medical devices.
US08652495B2	Oral care composition Disclosed are oral care compositions, for example dentifrice compositions, comprising an oral care composition comprising an orally acceptable vehicle, metal oxide particles having an average particle size of no greater than a dentin tubule and at least one amino acid capable of chelating the metal oxide. The composition may comprise a polymeric adherent material for adhering the metal oxide particles in the dentin tubule. The metal oxide particles have a median particle size of 5 microns or less, and may comprise zinc oxide.
US08652493B2	Hydrophobic agents stably dispersed in oil-in-water emulsions The present invention pertains to oil-in-water emulsion compositions having hydrophobic materials stably dispersed therein and methods for making such. The preferred method of making the emulsion compositions the formation of two O/W emulsions. A first O/W emulsion is for wetting or otherwise pre-treating the hydrophobic components. Thereafter, the first emulsion is added to a second O/W emulsion after the second emulsion has been formed. Both emulsions use a ternary surfactant blend of cationic, anionic and bridging surfactants, making the finished product a double or “binary-CAN” emulsion system. Generally, the system has a bi-modal oil droplet distribution.
US08652487B2	Tolerogenic synthetic nanocarriers for inducing regulatory B cells Disclosed are synthetic nanocarrier methods, and related compositions, comprising B cell and/or MHC Class II-restricted epitopes and immunosuppressants in order to generate tolerogenic immune responses, such as the generation of antigen-specific regulatory B cells.
US08652486B2	Neutralizing immunogen (NimIV) of rhinovirus and its use for vaccine applications The invention relates to methods and compositions for preventing or treating human rhinovirus infection.
US08652477B2	Methods for treating disseminated intravascular coagulation by inhibiting MASP-2 dependent complement activation In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a living subject. In one embodiment, the invention provides methods of treating a subject suffering from a complement mediated coagulation disorder, such as disseminated intravascular coagulation. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation. In some embodiments, the MASP-2 inhibitory agent inhibits cellular injury associated with MASP-2-mediated alternative complement pathway activation, while leaving the classical (C1q-dependent) pathway component of the immune system intact. In another aspect, the invention provides compositions for inhibiting the effects of lectin-dependent complement activation, comprising a therapeutically effective amount of a MASP-2 inhibitory agent and a pharmaceutically acceptable carrier.
US08652475B2	Inhibition of factor B, the alternative complement pathway and methods related thereto Disclosed are novel inhibitors of the alternative complement pathway and particularly, novel anti-factor B antibodies. Also disclosed is the use of such inhibitors to reduce or prevent airway hyperresponsiveness and/or airway inflammation by selectively inhibiting the alternative complement pathway, thereby treating diseases in which such conditions play a role. Also disclosed is the use of such inhibitors to reduce or prevent other diseases and conditions, including ischemia-reperfusion injury, by inhibition of the alternative complement pathway.
US08652474B2	Composition comprising antibody that binds to domain II of HER2 and acidic variants thereof A composition comprising a main species HER2 antibody that binds to domain II of HER2 and acidic variants thereof is described. Pharmaceutical formulations comprising the composition, and therapeutic uses for the composition are also disclosed.
US08652473B2	Antibodies to EGF receptor epitope peptides and uses thereof The present invention relates generally to growth factor receptor epitope peptides, particularly EGF family receptor epitope peptides. The invention also relates to the use of the receptor peptides in generating antibodies which have anti-tumor or anti-cancer activity or in stimulating an immunological response. The invention further relates to antibodies specifically directed against the receptor peptides. Methods for generating an immune response and for treatment of tumors and cancer are also provided.
US08652470B2	Monoclonal antibodies directed to CD52 The invention provides antibody to canine or feline or equine antigens, e.g., canine CDS2, and methods of making and using antibodies as described.
US08652462B2	Immune regulation A method of regulating the immune system of a subject that involves removing antigen presenting cells from subject and loading preselected class II peptide fragments onto the subjects APC's outside the body of the subject.
US08652461B2	Blood-cholesterol-lowering strain of Lactobacillus delbrueckii The invention relates to a novel strain of Lactobacillus delbrueckii having blood-cholesterol-lowering properties, and to the use thereof for the manufacture of blood-cholesterol-lowering fermented products, in particular of milk products.
US08652459B2	Splitting GP41 The present invention deals with a method for therapeutic or prophylactic treatment of HIV, in particular a prophylactic vaccinal method, comprising at least: administering to a patient a first antigen comprising the broadly neutralizing epitopes of the Membrane Proximal Ectodomain Region (MPER) of gp41, and administering to the same patient a second antigen comprising a modified polypeptide comprising three contiguous segments N, L and C represented by the formula N-L-C and comprising: a N-helix region of gp41(N), a C-helix region of gp41(C), and a connecting loop comprising a synthetic linker (L) between the N and C-helices, the linker replacing amino acids 593-617 of gp41, the numbering scheme being based upon the prototypic isolate HIV-1 HxB2 Clade B strain, said polypeptide comprising the calveolin-1 neutralizing and 98.6 D epitopes, but not 2F5 and 4E10 epitopes, not the fusion peptide, the polypeptide having a minimal immunogenic cross-reactivity with human interleukin 2.
US08652450B2	Soap-based liquid wash formulations with enhanced deposition of conditioning and/or skin appearance enhancing agents The invention relates to soap-based liquid body and facial wash compositions. Using high solvent, low water compositions and incompletely naturalized fatty acids to help structure the compositions, all in combination with modified benefit agents, enhanced deposition of conditioning and/or skin appearance and/or optical enhancing agents is achieved.
US08652442B2	Bioluminescence imaging of myeloperoxidase activity in vivo, methods, compositions and apparatuses therefor Methods of imaging distribution of myeloperoxidase activity in a subject are disclosed. These methods include the use of bioluminescent substrates, including luminol and wavelength-shifted analogues of luminol. Bioluminescent myeloperoxidase substrates that emit light at longer wavelengths compared to luminol are shown to be useful for imaging myeloperoxidase activity in vivo. The disclosed methods can be used for imaging sites of inflammation and other pathological conditions associated with abnormal levels of MPO activity in vivo. Methods of synthesis of luminol analogues are also disclosed.
US08652438B2	Central nervous system labelling composition for intranasal administration and labelling method and screening method using central nervous system labelling composition for intranasal administration There is provided a central nervous system labelling composition for intranasal administration for the purpose of labelling the central nervous system from the olfactory epithelium by way of the olfactory bulb and by means of intranasal administration. Additionally, there is provided a method of non-invasively labelling the central nervous system by way of an administration route that entails little transferability to the entire body. Furthermore, there is provided a screening method using a central nervous system labelling composition for intranasal administration. A central nervous system labelling composition for intranasal administration is characterized by labelling the central nervous system from the olfactory epithelium by way of the olfactory bulb and by means of intranasal administration and by containing at least one compound expressed either by the general formula (1) or the general formula (2) shown below as effective component:
US08652435B2	High pressure reduction-oxidation desulfurization process An improved process for reduction-oxidation desulphurization uses an oxidizer operating at a pressure greater than the absorber where a liquid reduction-oxidation catalyst solution contacts a sulfur-containing gas feed stream.
US08652431B2	Metal fluorophosphate synthesis and use as an active material for a battery electrode A method of synthesis of a metal fluorophosphate having the following general formula (1): XaMb(PO4)cFd (1), in which: X is an alkaline metal selected among sodium (Na) and lithium (Li) or a mixture of said metals; M is a transition metal selected among the following elements: Co, Ni, Fe, Mn, V, Cu, Ti, Al, Cr, Mo, Nb or a combination of at least two of said metals, 0≦a≦5; 0.5≦b≦3; 0.5≦c≦3; and d is an integer equal to 1, 2 or 3. The method contains an electric-field-activated sintering process for a mixture (1) formed by at least one first phosphate-containing solid precursor and at least one second fluorine-containing solid precursor.
US08652430B2	Organic dispersion of inorganic nano-platelets and method for forming the same The present invention provides an organic dispersion of inorganic platelets, which includes an organic solvent and H-form inorganic platelets dispersed therein. The H-form inorganic platelets have a particle size of between about 20 and 80 mm and the organic dispersion has a sold content of between about 1 and 20 wt %. A method for forming the organic dispersion is also provided.
US08652428B2	System and method for removing a contaminant from a gas stream A system and method for removing contaminants from a gas stream is provided. The method can include the steps of reacting the gas stream with ozone to form solid contaminant particles and separating the solid contaminant particles from the gas stream. The solid contaminant particles can he separated from the gas stream using an adsorption material.
US08652424B2	Labels, containers, system and method for providing reagents The invention relates to systems and methods for marketing and using products such as liquid materials, especially liquid reagents for use in microbiological and cellular biological laboratory settings include the use of unique color and simple numeric or alphanumeric identifiers to quickly and easily identify any product from a catalog list of products. Methods of marketing, advertising and producing such products are also disclosed. Particular embodiments include products, product packaging and product labeling. The invention also relates to collars and sleeves for containers, as well as related methods of use.
US08652418B2	Pipette for a pipette system having pipette and syringe A pipette for a pipette system comprising a pipette and a syringe. The pipette housing has a longitudinal axis. A syringe to be handled with the pipette is insertable with its fastening portion and plunger head into the pipette housing and is removable or discardable from said pipette housing in the direction of the longitudinal axis of the pipette housing, i.e., axially. The syringe has as cylinder and a plunger with a plunger head which projects out of the end of the cylinder even when the plunger has been completely inserted into the cylinder. A pipette housing comprises an axially accessible plunger gripping device for the plunger head of the syringe. An actuating device for the plunger gripping device is mounted on the plunger displacing device and is axially displaceable with said adjusting device.
US08652413B2	Mobile body disinfection apparatus A mobile body disinfection apparatus includes a carrying structure rendered mobile by means of a plurality of wheels attached thereto, a waste collection vessel, a liquid disinfectant dispensing element operated by a photoelectric cell and/or by a dispensing timer control, a filling tank, a supply line to carry the liquid disinfectant from the tank to the dispensing element, a waste tank connected to said washbasin, a drainage line and a central command and control unit suitable to manage at least the liquid disinfectant dispensing operations. The supply line comprises, in turn, at least one pump and one filter suitable to guarantee the elimination of infective elements that might be present in the water coming from the water distribution network and to guarantee a filtering of the liquid disinfectant that might have been contaminated even after filling the apparatus.
US08652408B2	Apparatus for execution of treatment operations on microscope slides with tissue specimens An apparatus for automatic execution of different treatment operations in connection with staining of tissue specimens on microscope slides, wherein the apparatus (1) comprises an assembly of vessels (4) for receiving different liquids for staining of the tissue specimens, a loading station (2) for microscope slides (28), a conveyor (5) for transfer of carriers with microscope slides from vessel to vessel in accordance with a treatment program, an unloading station (8) for treated microscope slides, and a control unit (18) for controlling the treatment operations in accordance with a data program. The apparatus comprises different levels (I, II) having units for execution of the relevant treatment operations. Thus, a first level (I) comprises the loading station (2) and the assembly of said vessels (4) with the appurtenant conveyor (5) and a second level (II) comprises a station (6) for application of cover glasses on the stained microscope slides (28), a succeeding station (7) for drying of the cover-slipped microscope slides, and the unloading station (8), a means (9) being provided for gripping and transfer of carriers (10) with stained microscope slides from the first level (I) to the cover-slipping station (6) on the second level (II).
US08652404B2	System and method for processing waste material A system for ozone sterilization of waste material, includes a tank configured to receive waste material, ozonated water, and ozone gas. The system further includes a pump coupled to the tank to receive the waste material and the ozonated water from the tank and form a slurry. The pump includes a cutter assembly to reduce a particle size of the slurry through cutting. Additionally, the system includes a circulation loop coupled between the tank and the pump to receive the slurry from the pump and re-circulate the slurry to the tank until the slurry is sterilized. A method for ozone sterilization of waste material is also disclosed.
US08652402B2	Portable gas generating device Methods and devices for generating gas from nitrous oxide are provided as well as downstream uses for the product gas. Reactor devices of the invention are compact and incorporate a novel heat-exchange/regenerative cooling system to optimize N2O decomposition and reactor durability.
US08652399B2	Sputtering target for producing metallic glass membrane and manufacturing method thereof A sputtering target for producing a metallic glass membrane characterized in comprising a structure obtained by sintering atomized powder having a composition of a ternary compound system or greater with at least one or more metal elements selected from Pd, Zr, Fe, Co, Cu and Ni as its main component (component of greatest atomic %), and being an average grain size of 50 μm or less. The prepared metallic glass membrane can be used as a substitute for conventional high-cost bulk metallic glass obtained by quenching of molten metal. This sputtering target for producing the metallic glass membrane is also free from problems such as defects in the metallic glass membrane and unevenness of composition, has a uniform structure, can be produced efficiently and at low cost, and does not generate many nodules or particles. Further provided is a method for manufacturing such a sputtering target for forming the metallic glass membrane.
US08652388B2	Rotational vacuum assisted resin transfer molding Thickness gradients in large, cobonded composite structures resulting from gravity-induced resin migration during curing is substantially reduced by rotating the structure during the resin infusion and curing stages. The layup for the structure is placed on a rotatable tool fixture and vacuum bagged. The tool fixture is mounted on a central support tube provided with motors for rotating the tool fixture about the axis of the tube. The tube has internal passageways that deliver resin to the bagged layup and carry away excess resin from the layup using vacuum pressure. The resulting composite structures exhibit thickness gradients less than 10%.
US08652387B2	Administering device with a multi-component injection-molded housing Method of producing an administering device for infusing or injecting a product, whereby in order to mold a housing shell serving as a case for components of the administering device in a multi-component injection molding process at least one pre-molded, transparent insert part made from a first plastic material is inserted in an injection mold molded to a shape matching the shape of the housing shell, a dimensionally stable, curable second plastic material is injected into the injection mold around the insert part to render it watertight and an opening left free in the second plastic material is closed to render it watertight by injecting on an elastomeric third plastic material.
US08652384B2	Method for molding semiconductor device An apparatus for molding a semiconductor device includes an upper mold chase and a lower mold chase. The mold chases are capable of being aligned with each other, forming spaced cavities for receiving a lead frame array that includes semiconductor dies for encapsulation. The cavities are aligned in spaced, vertical columns and gates are provided at the opening of each column of cavities. A molding compound is passed through the gates and flows uninterrupted through each cavity and encapsulates the semiconductor dies.
US08652383B2	Insert part weld molding method To provide an insert part weld molding method for reliably welding an insert part to a blow molded object while preventing an unwelded portion from being created at a circumferential edge of the insert part in a thickness direction thereof. An insert part weld molding method welds a blow molded object to an insert part 3 set in a mold 7, wherein a molding surface 7a of the mold 7 is set higher than a front surface 6d of a portion to be welded of the insert part 3, and an entire surface of a circumferential edge 6b of the insert part 3 in the thickness direction thereof and a parison 11 of the blow molded object are brought into a gapless welded state. Also adopted is a method of suppressing a decrease in temperature of the insert part 3 by arranging a preheating plate 8 which is made of a high thermal conducting material and which is to become a part of the molding surface 7a of the mold 7 in a vicinity of a portion where the parison 11 and the circumferential edge 6b of the insert part 3 in the thickness direction thereof are welded, and arranging a heat insulating plate 9 between the preheating plate 8 and the mold 7.
US08652381B2	Resin transfer molding device and resin transfer molding method A resin transfer molding (RTM) molding device is designed to mold a fiber-reinforced plastic (FRP) molded body by injecting a resin composition into a mold and by impregnating the molded body therewith. The resin composition is a chain curing polymer (CCP). A CCP accommodating layer is disposed adjacent to an outer side of the molded body. The layer contains the CCP. The layer is provided with a Vf limit value, the value defined by the curing characteristics of the CCP and the characteristics of dissipation of heat from the CCP to the exterior. An element for separating the molded body is disposed between the body and the layer.
US08652378B1	Uniform films for rapid dissolve dosage form incorporating taste-masking compositions The present invention relates to rapid dissolve thin film drug delivery compositions for the oral administration of active components. The active components are provided as taste-masked or controlled-release coated particles uniformly distributed throughout the film composition. The compositions may be formed by wet casting methods, where the film is cast and controllably dried, or alternatively by an extrusion method.
US08652375B2	Method and apparatus for making scrolls from exfoliatable materials A method of making scrolls is provided that includes providing a tape having a first side and second side wherein the first side of the tape is has an adhesive disposed thereon and the second side of the tape has a release coating disposed thereon, affixing the adhesive to a solid surface, buff-coating exfoliatable particles on the release side of the tape to form a coating; and peeling the tape from the solid surface at an angle. The coating separates from the release side of the tape and curls inwards to form scrolls. The scrolls can include graphite. Also provided is a continuous method of making scrolls and an apparatus.
US08652373B2	Hydroxyapatite poly(etheretherketone) nanocomposites and method of manufacturing same Hydroxyapatite-polymer nanocomposites, which are nanoparticles/microparticles, methods for making them, and articles made from them are disclosed. These methods are capable of preparing nanocomposites exhibiting more homogeneous dispersion of nanoparticles than is seen using previous methods. Such nanocomposites and articles are useful for a wide variety of applications, such as biological, medical, biochemical, biosensor, fuel cell, and aerospace applications.
US08652372B2	Method for producing single coal compacts suitable for coke chambers Coal compacts which are suitable for coking in coke oven chambers are prepared by pressing and compacting coal in a pressing device having a design which shapes the surface of the coal compacts to provide higher surface area. Already compacted coal blocks can be pressed to generate the surface shape. The resulting coal compacts exhibit significantly improved properties during the coking process, resulting in improved gas and heat exchange. A device for compacting coal preferably contains a plate provided with shaping elements on the pressing surface.
US08652366B2	Aerosol-mediated particle synthesis Disclosed are aerosol-mediated methods for synthesizing particles for biomedical and drug delivery applications. The method is based on the production of particles from sprayed polymeric micro or nano-droplets obtained by, for example, an air-jet nebulization process that is followed by gelation and/or hardening in a crosslinking fluid, non-solvent, precipitating solvent, or supercritical fluid.
US08652364B2	Polymer film, ultraviolet absorber, merocyanine compound and process for preparing merocyanine compound A polymer film comprising at least one compound represented by formula (I) is disclosed. A1 and A2 each independently represent a group having a Hammett's σp value of 0.2 or more, or bond each other to form a cyclic active methylene structure; and X1 and X2 each independently represent a hydrogen atom, aryl group, hetero-cyclic group, cyano, N-alkyl- or N-aryl-carbamoyl, or alkyl- or aryl-oxycarbonyl, or bond each other to form a saturated ring in which nitrogen and carbon atoms are embedded, and the group and ring may have at least one substituent.
US08652355B2	Self-adhesive base polymer for electroluminescence masses Self-adhesive polymer having a relative permittivity of more than 4.5 useful as a matrix of a self-adhesive electroluminescence mass.
US08652354B2	Organic additives for improved lifetimes in organic and solution processible electronic devices Organic additives are used to improve the lifetimes of organic electronic devices, such as electroluminescent devices fabricated from polymer luminescent ink. These additives include moisture getters, thermally-activated organic/inorganic hybrids, radical scavengers, antioxidants, UV stabilizers, and photoretarders. For water and oxygen scavengers, activation at elevated temperatures or through another activation method is preferred. This allows for the handling of the device materials containing the scavenger under a lower temperature condition in air where higher levels of ambiently-supplied water or oxygen may also be present. The invention also improves operational lifetimes as getters, scavengers and similar acting additives serve to reduce detrimental reactive species that transport into the device, are generated during operation, or become reactive during operation due to the presence of excited states or external stimulation by electrical, optical or other means.
US08652349B2	Apparatus, system and method of providing a de-icing saline solution for residential use A residential de-icing apparatus, system and method. The apparatus, system and method include a first saline solution having a salinity in a range of 150-360 ppt, a residential container having a volume in a range of 2-5 gallons, a second saline solution resident in the residential container and having a salinity in a range of 30 ppt-250 ppt, wherein the second saline solution results from a mixing of the first saline solution with a volume of water, and a hand-held output nozzle physically associated with the residential container for dispersing the second saline solution at a rate in a range of 6-12 gallons per ¼ mile.
US08652337B1	Self-formed nanometer channel at wafer scale A mechanism is provided for fabricating nanochannels for a nanodevice. Insulating film is deposited on a substrate. A nanowire is patterned on the film. Insulating material is deposited on the nanowire and film. A first circular hole is formed in the insulating material as an inlet, over a first tip of the nanowire to expose the first tip. A second circular hole is formed as an outlet, over a second tip of the nanowire opposite the first tip to expose the second tip. A nanochannel connects the first and second holes by etching away the nanowire via an etchant in the first and the second holes. A first reservoir is attached over the first hole in connection with the nanochannel at a previous location of the first tip. A second reservoir is attached over the second hole in connection with the nanochannel at a previous location of the second tip.
US08652333B2	Solvent removal A process for removing a solvent from a source solution, said process comprising a) contacting the source solution with one side of a selectively permeable membrane, b) contacting a draw solution having a higher osmotic pressure (higher solute concentration) than the source solution with the opposite side of the membrane, such that solvent from the source solution passes across the membrane to dilute the draw solution by direct osmosis, c) removing solvent from the diluted draw solution to regenerate the draw solution, and d) recycling the regenerated draw solution to step a), characterized in that a portion of the draw solution is discarded or treated before and/or after the draw solution is regenerated in step c) so as to reduce the concentration of any solute species present in the draw solution from the source solution.
US08652331B2	Membrane system backwash energy efficiency A method of backwashing a membrane filtration system comprising at least one permeable membrane, preferably a hollow fiber membrane, the method comprising the step of applying a pressurized gas at a variable pressure to permeate remaining present in the system when filtration process is stopped or suspended to provide liquid for backwashing pores of the permeable membrane during a backwashing process. Also provided are methods of filtering solids from a liquid suspension using alternating liquid backwash pressures.
US08652328B2	Apparatus for filtering water or wastewater A filter for removing at least some impurities (e.g. foreign matter of any nature including a solid, a liquid or a gas) from water or wastewater. A vibrator operably associated with at least a portion of the filter for imparting a vibrational force to enhance any one or more of numerous aspects of the filtration process including: (i) installation of the filter and/or various components thereof; (ii) servicing of the filter and/or components thereof; and, (iii) operation of the filter during a filtration cycle and a cleaning cycle.
US08652326B2	Device for the continuous electrochemical deionisation with integrated membrane unit A device for the electrodeionization of an aqueous electrolyte solution, comprises an electrodeionization module (1), an ultrafiltration module (21, 22, 1201, 1202, 1203) and a connection piece (3, 10) which connects the electrodeionization module (1) and the ultrafiltration module (21, 22, 1201, 1202, 1203) such as to be able to guide a diluate produced from the electrolyte solution during operation of the device in the electrodeionization module (1) from the electrodeionization module (1) to the ultrafiltration module (21, 22, 1201, 1202, 1203); wherein the connection piece (3, 10) is devoid of an adjustable pressure-maintaining valve. Via the pressure drop occurring in the ultrafiltration modules (21, 22, 1201, 1202, 1203), these devices build up a counter pressure behind the electrodeionization module (1) which is sufficient to ensure the packing density of the ion exchanger in the electrodeionization module (1).
US08652323B2	Filter assembly for use in drainage system A filter assembly for use in drainage systems to prevent the buildup of eroded materials such as soil, leaves and other debris is disclosed. The assembly includes a unitary frame and a filter media attached to the frame and is adapted to be retained within a component of a drainage sewer such as a catch basin. A porous material filter media such as a woven or non-woven geotextile allows for the flow of water through the filter while retaining debris or soil within the filter. The filter media extends into the basin to provide volume for the retained material without blocking the entire surface of filter.
US08652322B2	Multi-component part transducer assembly and a method for determining the pressure of a fluid using the transducer The invention relates to a multi-component part transducer assembly for determining the pressure of a fluid of interest. One part of the assembly comprises a reusable transducer, another part a disposable component comprising a flexible membrane which is in pressure connection with the fluid of interest, and another part comprises a locking component for securing the reusable and disposable parts together.
US08652316B1	Electrophoresis system with picture taking device An electrophoresis system includes a pedestal including a base, two enlargements at both ends of the base respectively, two cavities in the enlargements respectively, and a transparent plate on top of the base; a photographic filter member provided on the top of the base; a control panel on one enlargement; an electrophoresis tank provided between the enlargements; a covering member releasably provided on the pedestal for concealing the electrophoresis tank; a gel block in the electrophoresis tank for holding DNA samples in place; LED lamps in each cavity, the LED lamps being for emitting blue light toward the DNA samples; a hollow mount on the covering member and including a sliding tray; a photographic filter releasably disposed on the tray; and a picture taking device mounted on the hollow mount.
US08652310B2	Trim magnets to adjust erosion rate of cylindrical sputter targets A cylindrical magnetron sputtering apparatus includes a rotating cylindrical sputtering target, a non-rotating magnet structure within the cylindrical sputtering target and at least one non-rotating trim magnet adjacent an end of the magnet structure. The trim magnets are manipulated during operation of the apparatus to alter a magnetic field produced by the magnet structure within the cylindrical sputtering cathode. As a result the shape of a racetrack discharge plasma formed at an end of the sputtering target is altered such that the formation of an erosion groove is avoided.
US08652309B2	Sputtering apparatus and electronic device manufacturing method A sputtering apparatus comprises a substrate holder, and a screening member configured to screen a substrate mount surface of a surface of the substrate holder. The screening member comprises a first screening member configured to rotate about an axis in a first direction perpendicular to the substrate mount surface and screen at least a first area, and a second screening member configured to rotate about the axis and screen at least a second area. The first and second screening members are configured to be rotated to move between a screening position at which the first screening member screens at least the first area and the second screening member screens at least the second area and a retreat position at which the first and second screening members retract from an area above the substrate mount surface and overlap each other.
US08652306B2	Method for manufacturing mask blank, method for manufacturing transfer mask, sputtering target for manufacturing mask blank To provide a method for manufacturing a mask blank capable of manufacturing a high quality mask blank that suppresses generation of defects in a thin film for forming a mask pattern with high yields, a method for manufacturing a transfer mask that manufactures the thin film of the mask blank by patterning, and a sputtering target used for manufacturing the mask blank. By using the sputtering target containing silicon and having a hardness of 900 HV or more in Vickers' hardness, the thin film for forming the mask pattern on a substrate is formed by sputtering, and the high quality mask blank that suppresses generating of defects is manufactured, and further the transfer mask is manufactured by patterning the thin film.
US08652304B2	Process for separating solids from valuable or harmful liquids by vaporisation The present invention is directed to an enhanced process for separating dissolved and suspended solids from valuable or harmful liquids and more particularly to improving the operational aspects and separation efficiency of treating certain water miscible fluids including those used for oil and gas processing such as glycols, as well as automobile and aircraft fluids, that have become contaminated with dissolved and/or suspended solid matter.
US08652301B2	Method and composition for enzymatic treatment of fiber for papermaking, and paper products made therewith A method is provided for controlling organic contaminants, such as xylans, pitch or both, that interfere with bleaching of fibers and/or cause other interference(s) in papermaking systems. The method includes contacting fibers before any bleaching thereof with a composition which contains a hemicellulolytic enzyme and an organic contaminant removal adjuvant to liberate the organic contaminants from the fibers. The treated fibers can then be bleached and further used, for example, in making paper. The present invention also relates to the treatment compositions and to paper products made with fiber materials treated with these compositions. A method of enhancing enzymatic degradation of a substrate as well as formulations and systems for achieving the same are also provided. Various substrates can be degraded or otherwise processed, including biomass, paper mill sludge, and animal hides. Enzymatic degradation can be enhanced by including one or more polymeric surfactants.
US08652297B2	Symmetric VHF plasma power coupler with active uniformity steering A coaxial VHF power coupler includes conductive element inside a hollow cylindrical outer conductor of the power coupler and surrounding an axial section of a hollow cylindrical inner conductor of the power coupler. Respective plural motor drives contacting the hollow cylindrical outer conductor are connected to respective locations of the movable conductive element.
US08652296B2	Side gas injector for plasma reaction chamber A side gas injector for a plasma reaction chamber is provided. The side gas injector includes a circular distribution plate and a cover plate. The circular distribution plate includes an injection hole for injecting a reaction gas and a distribution channel part for distributing the reaction gas such that the reaction gas introduced from the injection hole can be radially simultaneously jetted in a plurality of positions along an inner circumference surface of the distribution plate. The cover plate is coupled to a top of the distribution plate and seals a top of the distribution channel part.
US08652295B2	CMP tool implementing cyclic self-limiting CM process A chemical mechanical polishing (CMP) apparatus includes a process controller operable to execute a multi-step CMP algorithm implementing delivering a first chemical composition onto the wafer surface while on a platen for a first time duration, and without removing the wafer from the platen, delivering a second chemical composition different from the first chemical composition onto the wafer surface for a second time duration. CMP is performed with a polishing pad contacting the wafer surface using a slurry including the first chemical composition during the first time duration or the second chemical composition during the second time duration, and a non-polishing process without any contact of the polishing pad to the wafer surface using the other of the first and second chemical composition during the other of the time durations, and repeating the multi-step CMP comprising process a plurality of times on the wafer.
US08652294B2	Composition and method of use for protecting knit fabrics A composition for the protection of sheer hosiery comprising: a styrene polymer; an octylacrylamide/acrylates/butylaminoethyl methacrylate copolymer; a polyurethane-14 AMP-acrylates copolymer; and an AMP-100™ (amino methyl propanol) or triethanolamine emulsifier and surfactant; dissolved in a denatured alcohol/ethanol solvent and contained in a pump spray bottle. The composition to be sprayed on a detected imperfection and the surrounding area, and being allowed to dry, binding in a flexible, natural manner the elongated and broken fibers of the material to the surrounding weave thus preventing further damage to the hosiery.
US08652293B2	Hydrophilic biodegradable adhesives A moisture-curable and biodegradable adhesive that includes the reaction product of: (a) an isocyanate component having an average functionality of at least 2; (b) an active hydrogen component having an average functionality greater than 2.1; and (c) an ionic salt component having an average hydroxyl or amino functionality, or combination thereof, of at least 1.
US08652292B2	Curved solid wood blockboard and method for its manufacture The invention allows the realization of parts, longitudinally or transversely curved, of large dimensions, by assembling boards of solid wood side by side, with glue, and to afterward arch the resulting part. The loss of solid wood is then decreased a lot since it is thus possible to assemble several wood boards of various widths together. It allows the realization of final curved parts of almost unlimited dimension, dimension whereas dimensions are usually limited by the width of the sawing, or, in other words, by the thickness of the trees. Here, the limit is situated at the level of the capacity of equipments used to bend solid wood.
US08652291B2	Method for coating substrates and carrier substrates A method for coating substrates, containing a) applying a composition to a first side of a substrate, the composition containing an inorganic compound and the inorganic compound containing a metal such as Sc, Y, Ti, Zr, Nb, V, Cr, Mo, W, Mn, Fe, Co, B, Al, In, Tl, Si, Ge, Sn, Zn, Pb, Sb, or Bi, and an element such as Te, Se, S, O, Sb, As, P, N, C, or Ga, b) drying the composition, c) applying a coating to the first side of the substrate, the coating containing a silane, oxide particles of Ti, Si, Zr, Al, Y, Sn, Zn, Ce or mixtures thereof, a polymer and an initiator, d) drying the coating, e) applying a barrier layer to a second side of the substrate, and f) drying the barrier layer to form a dry barrier layer.
US08652290B2	Systems and methods for manufacturing composite materials using thermoplastic polymers Apparatuses and methods for bonding together two or more layers of oriented polymer material or secondary material to form a rigid member. Two or more layers of material are initially restrained along an orientation axis to prevent contraction and loss of orientation. Then, the contact surfaces of each layer of material are heated to a temperature above the melting point for each respective material. Next, the heated contact surfaces are merged together, and pressure is applied to the merged contact surfaces to combine the layers. Once combined, the layers are cooled, and a rigid unitary member is formed.
US08652285B2	Method for producing a baseball or softball A method for producing baseballs and softballs, whereby a spherical core is independently formed and then a fiber material layer is attached, this fiber material layer is evenly brushed with a layer of polyurethane (PU), and this spherical core is placed in a ball cover mold made up of two or more mold pieces, and then heated, and finally the mold is removed to reveal the complete ball. Utilizing the production tool of this invention to produce the baseballs and softballs, whereby PU is brushed onto, and penetrates into the fiber material layer on the independently formed spherical core, resulting in the ball cover forming, the ball cover and spherical core attaches and fits firmly, and the porous construction of this fiber material layer attracts air, and therefore greatly avoids bubbles forming when the outer cover is formed, which affects the quality and lifespan of the ball.
US08652284B2	Vascular graft with kink resistance after clamping A self-sealing vascular graft with kink resistance is described. The vascular graft includes a substrate that can be ePTFE, having a self-sealing region that may include several layers of material. The central section of the vascular graft may be constructed differently from surrounding self-sealing regions, in order to provide kink resistance following the clamping of the graft. Also described is a graft with a flared cuff attached to one or both ends, the attachment or transition region including reinforcement beading.
US08652281B2	Spinel ceramics via edge bonding Disclosed herein is a method for making transparent ceramic spinel windows, domes and other complex shapes via edge bonding.
US08652278B2	Method for producing a shaped body using fibers A shaped body comprised of individual, interconnected layers may be produced from fibers in accordance with a solid freeform fabrication or rapid prototyping method. The fibers may be produced by extrusion molding a thermoplastic material.
US08652274B2	Copper alloy with high strength and high conductibility, and method for manufacturing same A copper alloy includes Si to facilitate deoxidation, and can be easily manufactured even when including elements such as Cr or Sn. The copper alloy has high conductivity and high workability without negatively affecting the tensile strength. The copper alloy contains 0.2 to 0.4 wt % of Cr, 0.05 to 0.15 wt % of Sn, 0.05 to 0.15 wt % of Zn, 0.01 to 0.30 wt % of Mg, 0.03 to 0.07 wt % of Si, with the remainder being Cu and inevitable impurities. A method for manufacturing the copper alloy includes obtaining a molten metal having the described composition; obtaining an ingot; heating the ingot at a temperature of 900-1000° C. to perform a hot rolling process; cold rolling; performing a first aging process at a temperature of 400-500° C. for 2 to 8 hours; cold rolling; and performing a second aging process at a temperature of 370-450° C. for 2 to 8 hours.
US08652272B2	Suppression method for corrosion of carbon steel member A bath containing nickel ions and formic acid is injected into a film-forming aqueous solution flowing in a circulation pipe connected to a feed water pipe made of carbon steel in a BWR plant. This solution is supplied into the pipe through the circulation pipe, and a nickel metal film is formed on an inner surface of the pipe. After the film is formed, a film-forming aqueous solution containing iron (II) ions, formic acid, nickel ions, hydrogen peroxide, and hydrazine is supplied to the pipe. A nickel ferrite film is formed on the surface of the nickel metal film in the pipe. The nickel ferrite film comes into contact with water containing dissolved oxygen at or above 150° C. to transform the nickel metal film into a nickel ferrite film. A thick nickel ferrite film is formed on the inner surface of the feed water pipe.
US08652267B2	Coated-type silicon-containing film stripping process There is disclosed a coated-type silicon-containing film stripping process for stripping off to remove a coated-type silicon-containing film obtained by coating a silicon-containing film composition used in a lithography on a substrate, comprising, at least: a first step of treating the silicon-containing film with an acidic stripping solution containing sulphate ion and/or fluoride ion; and a second step of treating the silicon-containing film with an alkaline stripping solution containing a nitrogen compound. There can be provided a process for allowing a silicon-containing film, which has not been conventionally removed unless dry stripping is adopted, to be removed by a stripping process based on a stripping solution (wet stripping).
US08652263B2	Cleaning bucket system for flat mops A double bucket cleaning system for use with microfiber mat mops. One bucket contains clean water; the second holds dirty water. The second bucket has a slide press for extracting dirty water from the mop. The system can use a connector to connect the two buckets together, or a single bucket with two compartments can be used. Both designs use a footpad upon which the user stands during the pressing operation. This ensures that the device remains in place during the sliding. Finally, once the dirty water has been extracted from the mop, the user can pick up clean water from the first bucket for the next portion of the floor to be cleaned. In this way, the user is able to quickly clean a large floor with clean water, instead of repeatedly dipping the mop back into dirty water.
US08652262B2	Ultrasonic cleaning method for generating ultrasonic vibrations by a frequency modulated signal An ultrasonic cleaning method of using ultrasonic vibrations to clean an object that is immersed in a cleaning liquid in a cleaning tank is provided. The method includes generating a frequency modulated signal including at least two frequency modulated portions having modulation widths different from each other with a single frequency as a center frequency, such that among the at least two frequency modulated portions a frequency modulated portion having a smaller modulation width is generated at a timing when a frequency modulated portion having a larger modulation width reaches the center frequency. The method further includes generating the ultrasonic vibrations based on the frequency modulated signal and transferring the ultrasonic vibrations to the cleaning tank to clean the object.
US08652255B2	Method of producing epitaxial layers with low basal plane dislocation concentrations A method of: flowing a silicon source gas, a carbon source gas, and a carrier gas into a growth chamber under growth conditions to epitaxial grow silicon carbide on a wafer in the growth chamber; stopping or reducing the flow of the silicon source gas to interrupt the silicon carbide growth and maintaining the flow of the carrier gas while maintaining an elevated temperature in the growth chamber for a period of time; and resuming the flow of the silicon source gas to reinitiate silicon carbide growth. The wafer remains in the growth chamber throughout the method.
US08652253B2	Arrangement and method for manufacturing a crystal from a melt of a raw material and single crystal An arrangement for manufacturing a crystal of the melt of a raw material comprises: a furnace having a heating device with one or more heating elements, which are configured to generate a gradient temperature field directed along a first direction, a plurality of crucibles for receiving the melt, which are arranged within the gradient temperature field side by side, and a device for homogenizing the temperature field within a plane perpendicular to the first direction in the at least two crucibles. The arrangement further has a filling material inserted within a space between the crucibles wherein the filling shows an anisotropic heat conductivity. Additionally or alternatively, the arrangement may comprise a device for generating magnetic migration fields, both the filling material having the anisotropic heat conductivity and the device for generating magnetic migration fields being suited to compensate or prevent the formation of asymmetric phase interfaces upon freezing of the raw melt.
US08652252B2	Extrusion molding hydraulic composition A hydraulic composition comprising a water-soluble hydroxyalkyl alkyl cellulose, cement, aggregate, reinforcing fibers, and water is provided. The hydroxyalkyl alkyl cellulose has a degree of alkyl substitution of 1.2-1.7, the sum of the degree of alkyl substitution and the molar substitution of hydroxyalkyl is 1.5-2.0, and a proportion of glucose ring not substituted with alkyl and hydroxyalkyl groups per glucose ring unit is up to 10 mol %. The composition cures within a short time and is extrusion moldable even at elevated temperature.
US08652250B2	Composition used for high-strength and impermeable concrete A composition used for high-strength impermeable concrete. The composition contains sand, stone, cement, water reducer, water and reinforced impermeable sand. The reinforced impermeable sand includes aeolian sand and binder covering the surface of the aeolian sand. The reinforced impermeable sand can fill the gap between the sand and the stone, and well combine various components in the composition, and suppress the seepage phenomenon of the molded concrete, thereby greatly improving the strength and impermeability of the concrete.
US08652248B2	Cement mixes containing additives for altering the hardening rate of chemically bonded silico-phosphate cements and methods therefor A cement mix for preparation of a magnesium silico-phosphate cement (MSPC) with an altered hardening rate is provided. The cement mix comprises on the order of 1% of an [MF6]n− salt or acid. Upon addition of water, the mix produces a final set cement that has similar physical properties to those of a cement prepared from a mix lacking the additive, but with a significantly altered setting time. In some embodiments of the invention, the additive is provided in the form of a coating for the MgO component of the mix. In preferred embodiments, H2TiF6, Na2TiF6 and/or K2TiF6 are used as retarders, while K3AlF6 is used as an accelerant. Other embodiments use M′nMF6 compounds wherein M′ is an alkali metal, an alkaline earth metal, or H, and M is chosen from inter alia Ti (n=2), Zr (n=2), P (n=1), Al (n=3), and Sb (n=1).
US08652243B1	Gas filtration system A gas filtration apparatus includes a first pipeline configured to divide transmitted gas and air to second and third gas flows, transmit the second and third gas flows to second pipeline bundle which is configured to divide each of the second and third gas flows to two or more gas flows and transmit the divided gas flows to a plurality of filters, a purifying tank configured to contain first water for purifying the divided gas flows, a plurality of filters positioned in a lower space of the purifying tank and configured to disintegrate one or more bubbles created by the divided gas flows, and a gas outlet configured to collect a plurality of bubbles emitted from the first water and release the collected bubbles to the outside of the gas filtration apparatus.
US08652237B2	System and process for capture of H2S from gaseous process streams and process for regeneration of the capture agent A system and process are disclosed for selective removal and recovery of H2S from a gaseous volume, e.g., from natural gas. Anhydrous organic, sorbents chemically capture H2S gas to form hydrosulfide salts. Regeneration of the capture solvent involves addition of an anti-solvent that releases the captured H2S gas from the capture sorbent. The capture sorbent and anti-solvent are reactivated for reuse, e.g., by simple distillation.
US08652236B2	Method for recovery of high purity carbon dioxide The present invention describes a method for recovery of high purity carbon dioxide, which is substantially free of nitrogen oxides. This high purity carbon dioxide is obtained by introducing into the method a step in which carbon dioxide absorbed in an absorbing agent is flashed. The present invention also discloses a plant for recovery of said high purity carbon dioxide comprising an absorption column, a flash column, a stripper column, and a down stream purification unit comprising a washing column, a dehydrator, a condenser and a distillation unit.
US08652231B2	Metal complexes; use thereof for the preparation of compositions for agricultural use Novel metal complexes useful in the area of agriculture, notably as agents for treating metal deficiency. The novel metal complexes comprise at least one metal selected from the metal trace elements essential for the development of plants, at least one first ligand selected from the lignosulfonates, and derivatives thereof, and at least one second ligand selected from the multidentate organic ligands.
US08652229B2	Particle filter system incorporating nanofibers A filtration device including a filtration medium having a plurality of nanofibers of diameters less than 1 micron formed into a fiber mat in the presence of an abruptly varying electric field. The filtration device includes a support attached to the filtration medium and having openings for fluid flow therethrough. A device for making a filter material. The device includes an electrospinning element configured to electrospin a plurality of fibers from a tip of the electrospinning element, a collector opposed to the electrospinning element configured to collect electrospun fibers on a surface of the collector, and an electric field modulation device configured to abruptly vary an electric field at the collector at least once during electrospinning of the fibers. A method for making a filter material. The method provides a support having openings for fluid flow therethrough, electrospins nanofibers across an entirety of the openings, and abruptly varies an electric field at the collector at least once during electrospinning of the fibers.
US08652226B2	Abrasive particles having a unique morphology An abrasive particle having an irregular surface, wherein the surface roughness of the particle is less than about 0.95. A method for producing modified abrasive particles, including providing a plurality of abrasive particles, providing a reactive coating on said particles, heating said coated particles; and recovering modified abrasive particles.
US08652223B2	Combined synthesis gas generator In various systems and processes, synthesis gas generation may be combined. A partial oxidation reactor (POX) and a gas convectively heated steam/hydrocarbon catalytic reformer (GHR) may be combined to produce synthesis gas. In some implementations, a partial oxidation reactor, a gas convectively heated steam/catalytic reformer, and a waste hat boiler may be combined to produce synthesis gas.
US08652217B2	Prosthetic device utilizing electric vacuum pump Prosthetic devices having vacuum components operative to evacuate the interior of a prosthetic socket thereof, and control systems for use therewith. The evacuation devices preferably include at least an electrically powered vacuum pump and associated power source, and a vacuum accumulator connected to the vacuum pump. Associated control systems may be of various designs and may employ wired or wireless communication. Control of an evacuation device may be based on vacuum level, residual limb volume, residual limb motion, user activity level or other device parameters.
US08652216B2	Self deploying implant in needle Described, in certain inventive embodiments, are unique devices and methods for introducing implants into soft tissue of a patient. One of these devices includes a tissue-penetrating member that is configured to pass in its entirety through a volume of patient tissue. The tissue-penetrating member has a leading end and a trailing end, and provides a receiving space for receipt of an implant body portion for carrying the implant body portion into the volume of patient tissue. The device also includes an implant that has an implant body portion removably received in the receiving space of the tissue-penetrating member. The implant body portion is configured for deployment from the receiving space in the volume of patient tissue so as to remain deployed there along a passageway traversed by the tissue-penetrating member.
US08652215B2	Nanofilament scaffold for tissue regeneration A scaffold for tissue regeneration is provided. In a preferred embodiment, the scaffold is implantable in a patient in need of nerve or other tissue regeneration and includes a structure which has a plurality of uniaxially oriented nanofibers made of at least one synthetic polymer. Preferably, at least 75% of the nanofibers are oriented within 20 degrees of the uniaxial orientation. The scaffold beneficially provides directional cues for cell and tissue regeneration, presumably by mimicking the natural strategy using filamentous structures during development and regeneration.
US08652210B2	Femoral prostheses with lateral buttress for patella Knee prostheses featuring components that more faithfully replicate the structure and function of the human knee joint in order to provide, among other benefits: greater flexion of the knee in a more natural way by promoting or at least accommodating internal tibial rotation in a controlled way, replication of the natural screw home mechanism, and controlled articulation of the tibia and femur respective to each other in a more natural way. In a preferred embodiment, such prostheses include an insert component disposed between a femoral component and a tibial component, the insert component preferably featuring among other things a reversely contoured posterolateral bearing surface that helps impart internal rotation to the tibia as the knee flexes. Other surfaces can also be specially shaped to achieve similar results, preferably using iterative automated techniques that allow testing and iterative design taking into account a manageable set of major forces acting on the knee during normal functioning, together with information that is known about natural knee joint kinetics and kinematics.
US08652207B2	Plug components for bone tunnel A component for satisfactorily plugging a bone tunnel formed in surgery such as ACL reconstruction by regenerating bone in a space portion of the bone tunnel (e.g., a bone tunnel for an arthroscope). The plug component is made of a calcium phosphate-based material, and includes a porous part having a porosity of 50 to 85%. The plug component has a cylindrical shape such that one of its end surfaces forms an angle of 30 to 60 degrees to its central axis.
US08652200B2	Medical devices comprising drug-loaded capsules for localized drug delivery A medical device comprising a plurality of capsules, and a method of administering therapeutic agent to a patient using the same. The capsules further comprise a therapeutic agent and a multilayer polyelectrolyte shell. The medical device is adapted to apply a pressure to the capsules that is greater than or equal to the critical pressure of at least a portion of the capsules, such that therapeutic agent is released from the capsules.
US08652196B2	Stent A stent and associated method for implanting a stent within a body conduit are provided. According to one embodiment, the stent includes a plurality of annular segments arranged peripherally along a longitudinal axis to define opposing free ends, wherein each annular segment includes a plurality of interconnected segment struts. The stent also includes a plurality of connector struts each extending along the longitudinal axis between, and connecting, adjacent annular segments, wherein each connector strut includes an axial section and a compensating section. In addition, at least a portion of each of the segment struts, axial sections, and compensating sections is curved.
US08652192B2	Stent and system and method for deploying a stent The present invention is a vascular stent comprising a cylindrical wall radially expandable from a compressed state to an expanded state and including a plurality of cells. At least one cell includes a first primary member having a first restrainer member and a second primary member having a second restrainer member. When the cylindrical wall is in the expanded state, the first and second primary members are located a greater distance from each other than when the cylindrical wall is in the compressed state. The first and second restrainer members join to maintain the cylindrical wall in the compressed state. An expansion force applied to the cylindrical wall causes the first and second restrainer members to separate, thereby freeing the cylindrical wall to expand from the compressed state to the expanded state.
US08652187B2	Cuff apparatus and method for optical and/or electrical nerve stimulation of peripheral nerves Apparatus and method for making and using devices that generate optical signals, and optionally also electrical signals in combination with one or more such optical signals, to stimulate (i.e., trigger) and/or simulate a sensory-nerve signal in nerve and/or brain tissue of a living animal (e.g., a human), for example to treat nerve damage in the peripheral nervous system (PNS) or the central nervous system (CNS) and provide sensations to stimulate and/or simulate “sensory” signals in nerves and/or brain tissue of a living animal (e.g., a human) to treat other sensory deficiencies (e.g., touch, feel, balance, visual, taste, or olfactory) and provide sensations related to those sensory deficiencies, and/or to stimulate (i.e., trigger) and/or simulate a motor-nerve signal in nerve and/or brain tissue of a living animal (e.g., a human), for example to control a muscle or a robotic prosthesis.
US08652184B2	Resonant frequency device A resonant frequency device provided with a transmitter, an amplifier and an impedance matching circuit connected to an antenna, such as a plasma antenna. A voltage or current balun could be provided between the impedance matching circuit and the antenna.
US08652183B1	Multi-angle orthopedic expansion head fastener The disclosed fasteners have a substantially cylindrical expansion head to secure the fastener in a support structure. The expansion fastener has a removable locking ring, a head, and a shaft extending from the distal end of the head. The exterior of the head has at least one slot extending from the edge toward the distal end. The slots can extend partially or fully to the base of the head. In one embodiment the locking ring has at least one tab that extends beyond the periphery and a tool receiving area. In one embodiment a channel having wall periphery reduction area receives a locking ring with tabs which, when rotated to contact the reduction areas expand the head. In another embodiment the locking ring has a threaded periphery that interacts with a reduced diameter threaded periphery within the head to expand the exterior of the head.
US08652182B1	Bone plate with retainer and stop for screw lock A bone plate, having a bone screw and a rotatable lock for retaining the bone screw in place, includes a retainer element and/or a stop element. The retainer element inhibits the lock from being pushed off of the bone plate, while the stop element limits the rotational range of motion of the lock.
US08652178B2	Polyaxial pedicle screw assembly and method A method comprising attaching a screw head to a bone fixator component, wherein the screw head comprises a first portion comprising a slot and an inwardly curved bottom portion; and a second portion comprising an outwardly protruding and expandable bulbous end extending from the inwardly curved bottom portion; and wherein the bone fixator component comprises a concave socket adapted to receive the screw head; securing the bone fixator component in a bone; securing a locking pin in the screw head; engaging the locking pin with the bone fixator component; inserting a longitudinal member in the screw head; and inserting a blocker in the screw head.
US08652177B1	Systems and methods for treating spinal deformities Systems and methods of treating spinal deformity, including one or more intervertebral implants to be introduced laterally into respective intervertebral spaces, a plurality of bone screws introduced generally laterally into vertebral bodies adjacent to the intervertebral implants and/or the intervertebral implants themselves, and a cable dimensioned to be coupled to the bone screws and manipulated to adjust and/or correct the spinal deformity.
US08652174B2	Expandable interspinous process spacer An expandable interspinous process spacer implant for insertion and/or implantation between a spinous process of a superior vertebral body and a spinous process of an inferior vertebral body, the implant comprising multiple pairs of legs joined in a scissor-like fashion and pivotally coupled to each other by one or more pins, where each leg has multiple slots along its longitudinal axis. The implant further may include a pair of bearing surfaces coupled between the legs via cross pins and a first plate and second plate each of which is coupled to a pair of roller pins disposed between a pair of slots on the legs where rotation of a fastener in the fastener holes of the first and second plate results in the first plate and the second plate being drawn toward each other causing the expansion of the height of the implant.
US08652172B2	Flexible anchors for tissue fixation An anchor for securing tissue to bone can include a flexible first tubular member, a flexible second tubular member, and a first suture member. The first tubular member can include a first wall defining a first passage between first and second ends. The second tubular member can include a second wall defining a second passage between first and second ends. The first suture member can couple the first tubular member and the second tubular member. The first suture member can pass through the first wall and the first passage and the second wall and the second passage. The first tubular member and the second tubular member can engage each other and deform to form an anchoring mass upon tensioning the first suture member. A method of preparing an anchor for securing tissue to bone and a method of securing a tissue to a bone are also provided.
US08652170B2	Double ended barbed suture with an intermediate body A suture system has a double ended barbed suture with a first plurality of barbs located adjacent to a first end and a second plurality of barbs located adjacent to a second end, and a body located between the first plurality of barbs and the second plurality of barbs. The body provides an anchor that can hold tissue relative to the first end and the second end of the suture. The body can slide and be positioned on said suture.
US08652168B2	Clotting cascade initiating apparatus and methods of use and methods of closing wounds Wound closure methods and apparata are provided which utilize blood fluid by activating the clotting cascade of the blood fluid outside the body within a substantially enclosed sterile container then introducing the blood fluid to the wound site to complete clotting. Methods and apparata for providing ways of inhibiting anticoagulants and slowing fibrin clot degradation are also disclosed. Kits for practicing the invention singularly or in combination with and/or associated with preferred procedures are also disclosed.
US08652166B2	Insertion tool for a medical closure device Insertion tool for a medical closure device for the sealing of an opening in a wall of a bodily organ, comprising a tamping force source adapted to deliver a first member to a position at the opening on one side of the wall subsequently to a second member being positioned at the opening on the opposite side of the wall. The tamping force source, which is energized prior to the tamping procedure, can be for example a spring, an elastic band or a pressurized gas container. A tamping spring can be compressed or extended upon loading. The tamping force source can be released in response to a manual operation or be triggered by retraction of the insertion tool.
US08652163B2	Apparatus and method for deployment of a therapeutic device using a catheter The apparatus for deployment of an intravascular therapeutic device, includes an elongated, flexible pusher member and a therapeutic device connected to a severable portion of a first connector member mounted to the flexible pusher member with an elongated second connector member connected to the therapeutic device. The first connector member or second connector member may be capable of being broken by heat, and a heat source is provided for heating and breaking the first connector member or the second connector member to release the therapeutic device.
US08652162B2	Catheter, catheter assembly and relevant method The present invention relates to a catheter suitable for conducting and positioning a medical device in an organic cavity comprising at least one side branch, such as a blood vessel, which comprises a tubular body, having a central lumen having a cross-section suitable for the passage of the medical device and a mandrel slidable in the central lumen and distally a flexible end portion. On the outer surface of the mandrel there is a longitudinal groove defining, with the inner wall of the tubular body, a passage suitable for receiving a first guide wire in a sliding manner. In addition, in the mandrel there is an inner lumen suitable for housing a second guide wire in a sliding manner. The present invention further relates to a catheter assembly comprising the aforesaid catheter and a method of use the same.
US08652156B2	Surgical instrument A morcellator (1) for morcellating tissue within a body cavity of a patient is provided in combination with first (17) and second (18) tissue-pulling devices, and an insert (19). The morcellator (1) comprises a handle portion (2) having a lumen (6) passing therethrough, and an aperture (10) communicating with the proximal end of the lumen. A tube (3) extends from the handle portion and has a tissue cutting device (7) located at the distal end of the tube. The handle includes first (11) and second (12) valves associated with the lumen of the handle portion, and the first and second tissue-pulling devices have shafts of a first diameter and second diameter respectively. The insert (19) comprises a stem (21) and a body portion (20), the stem being received in the aperture (10) to form a substantially gas-tight seal in combination with the first valve (11). The body portion (20) remains outside the aperture and includes a third valve (22), the third valve (22) being such that is forms a substantially gas-tight seal around the shaft of the second tissue pulling device (18) when the second tissue pulling device is inserted into the lumen of the insert.
US08652152B2	Clip applying apparatus and ligation clip A clip applying apparatus is provided for applying a ligating clip to tissue. The clip applying apparatus includes, inter alia, a handle assembly, a central body portion, an anvil jaw, and a slide member movably supported in relation to the anvil jaw. The anvil jaw and the slide member are configured to define an enclosed tissue receiving area when the slide member is in an advanced position. A method is also provided for ligating tissue using the presently disclosed clip applying apparatus.
US08652147B2	Device for isolating and removing tissue from a body cavity A tissue isolation and removal device has a containment pouch that is opened and supported by the device. The pouch has two open/close portions both able to be closed and reopened. One portion positioned away from tissue being inserted in the pouch and covering the other portion to enclose or isolate any tissue captured in the other portion.
US08652144B2	Midline referencing femoral sizing caliper A sizing caliper for facilitating the selection of a femoral component of a knee prosthesis includes a caliper body, a drill guide body, a stylus tower and a graduated stylus slidably coupled to the stylus tower. The caliper body, the stylus tower and the two drill guide body portions are configured to be slidably linked to each other, whereby as the caliper body and the stylus tower are linearly displaced, in opposite directions along the longitudinal axis L of the sizing caliper, relative to the two drill guide body portions, the caliper body and the stylus tower are linearly displaced at an equal rate relative to the drill guide body portions and the drill guide holes remain located at the midpoint of an anterior/posterior dimension defined by the distance between the tip of the stylus and the base portion.
US08652143B2	Inserter device used for orthopedic surgery A surgical tool for inserting an implant in a vertebral body. The surgical tool includes a shaft with a shaft thread adapted to engage the implant, a piston coupled to the shaft thread to articulate the implant from a starting linear position to a final curvilinear position, an actuator coupled to the piston to adjust a position of the implant, and an annular structure surrounding the shaft to increase a stability of an end part of the implant on an impact of insertion. A screw attached to the piston may lock the end part of the implant. A lock lever may lock the position of the piston in at least one position, and a knob may disengage the implant from the surgical tool.
US08652142B2	Osteotomy systems Systems, including methods, apparatus, and kits, for performing osteotomies to cut bone and, optionally, to adjust bone length.
US08652141B2	Methods and devices for treating hallux valgus The various embodiments disclosed herein relate to implantable devices for the treatment of structural bone and joint deformity, including hallux valgus. More specifically, the various embodiments include systems, devices, and methods for implantation of a flexible or tension band for treating such deformity.
US08652135B2	Surgical forceps A forceps includes a housing having a shaft attached thereto and an end effector assembly disposed at a distal end of the shaft. The end effector assembly includes first and second jaw members disposed in opposed relation relative to one another. At least one of the jaws is moveable with respect to the other between a spaced-apart position and an approximated position for grasping tissue between the jaw members. A cutting assembly is disposed within a cavity defined within the first jaw member. The cutting assembly includes a cutting member that is rotatably coupled to the first jaw member and configured to rotate with respect to the first jaw member about a longitudinal axis thereof to cut tissue disposed between the jaw members.
US08652134B2	Single-use electronic apparatus having a thermal switch An electronic apparatus includes a circuit portion that is configured to control an operation of the electronic apparatus and a heat-activated mechanical switch including, for example, a shape-memory material. The shape-memory material has a property such that the shape-memory material assumes a predetermined shape when the electronic apparatus is heated to a transition temperature. The shape-memory material disables the apparatus by acting on the circuit portion when the shape-memory material assumes the predetermined shape.
US08652131B2	Eye therapy system A system for applying therapy to an eye selectively applies coolant to the corneal surface to minimize heat-related damage to the corneal surface during thermokeratoplasty. Embodiments may include an energy source, a conducting element, a coolant supply, and a coolant delivery system. The conducting element is operably connected to the energy source and extends from a proximal end to a distal end. The conducting element directs energy from the energy source to the distal end, which is positionable at the eye. The coolant delivery system is in communication with the coolant supply and is operable to deliver a micro-controlled pulse of coolant to the distal end.
US08652130B2	Method and device for soft tissue ablation A method and device for fractional skin treatment. The method includes the application of a HV pulse to the skin surface through an array of pin electrodes.
US08652129B2	Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation Apparatus, systems, and methods for achieving thermally-induced renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver a thermal element to a renal artery via an intravascular path. Thermally-induced renal neuromodulation may be achieved via direct and/or via indirect application of thermal energy to heat or cool neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers.
US08652128B2	Electrosurgical system having a sensor for monitoring smoke or aerosols An electrosurgical system includes an electrosurgical generator configured to generate electrosurgical energy and a sensor. The sensor is coupled to the electrosurgical generator and senses aerosol and/or smoke generated during application of the electrosurgical energy. The sensor generates data in response to the sensed aerosol and/or smoke and communicates the data to the electrosurgical generator. The electrosurgical generator generates the electrosurgical energy as a function of the data.
US08652122B2	Laser device and method for machining material using laser radiation Disclosed is a laser device for machining material, comprising a laser beam source which supplies pulsed laser radiation, and a variable deflection unit that introduces said laser radiation into the material at different, selectable points so as to create optical breakthroughs. The inventive laser device further comprises a pulse-selecting apparatus which modifies selected laser pulses of the pulsed laser radiation regarding at least one optical parameter in such a way that no more optical breakthroughs can be created using the modified laser pulses.
US08652121B2	Universal medical device control console A control console is disclosed for controlling one or more medical devices. The control console communicates to at least one medical device, and at least one peripheral module associated with the medical device if needed. The control console has a microprocessor for processing data to direct an operation of the medical device.
US08652119B2	Guidewire A guidewire having high rotational torque transmissibility and high pushing torque transmissibility and having favorable restorability is provided. The guidewire has an outer coil having a tapered coil portion constituted by at least one strand wound to decrease an outer diameter toward a front end of a core shaft and an inner coil arranged inside the outer coil. An outer diameter on a front side of the inner coil arranged on a front side of the tapered coil portion is smaller than an outer diameter on a rear side of the inner coil.
US08652115B2	Insert with advantageous fastener configurations and end stiffness characteristics for two-piece wearable absorbent article A two-piece wearable absorbent article (such as a diaper) including an outer cover, and particularly, an absorbent insert for use therewith, are disclosed. The insert has a fastener component disposed at either or both a forward region and a rearward region thereof, for fastening the insert within the outer cover. The end of the insert associated with the region bearing the fastener component may have a specified stiffness, to help the insert to retain structural integrity while fastened within an outer cover and while being worn. The insert may include an end support stiffener that helps impart stiffness.
US08652112B2	Ostomy device An ostomy device is provided including an ostomy pouch having an entrance opening, a body attachment wafer having a through-going opening and a coupling layer, which couples the pouch to the body attachment wafer and has a central opening therein. The body attachment wafer includes a plastic film, which is coated with a layer of skin friendly adhesive on the side thereof distal to the ostomy pouch. The coupling layer is affixed to the body attachment wafer along an attachment line extending around the central opening in the coupling layer, the attachment line being distanced from the central opening in the coupling layer. The region around the entrance opening of the pouch is affixed to the coupling layer in a landing zone located between the attachment line and the opening in the body attachment wafer.
US08652111B2	Reduced-pressure treatment systems with reservoir control A reduced-pressure system for delivering reduced pressure for medical purposes to a desired site and to receive fluids in one instance includes a reservoir having an interior space operable to contain the fluids. A reduced-pressure delivery conduit is placed in fluid communication with the interior space for delivering the reduced pressure to the desired site. A source conduit and a pressure sensor conduit are placed in fluid communication with the interior space. A pressure sensor is placed in fluid communication with the pressure sensor conduit. A reduced-pressure source is placed in fluid communication with the source conduit. A reduced-pressure control unit is associated with the pressure sensor and the reduced-pressure source and is operable to receive pressure data from the pressure sensor and supply data from the reduced-pressure source and to determine when a reservoir-full/blockage condition exists. Other systems and methods are presented.
US08652110B2	Valve-equipped hand switch and chemical liquid introduction system In a valve-equipped hand switch and a chemical liquid introduction system, a contrast medium in a syringe is delivered to a patient line through a first port, a main passage around a spacer portion, and a second port. Furthermore, a pressure (about 300 psi) of the contrast medium delivered by a chemical liquid introduction device is transmitted as a reaction force through a third plunger from a handle portion of an operation piston held by an operator. As such, the operator can directly feel the pressure of the introduced contrast medium, which gives a sense of ease to the operator during operation.
US08652109B2	Syringe with integrated valve male luer lock connector Syringe (1) including a cylinder (2) and a piston (4), in which the outlet end (6) of the cylinder (2) is integrated with a valve male luer lock connector (7).
US08652107B1	Article for securing a catheter An article prevents a drainage tube or catheter from being inadvertently moved, removed, or constricted. The article generally includes (i) a hollow conduit having a medial bend formed with an angle of between 45 and 135 degrees, and further having a lateral opening in a wall of the conduit, the opening exposing an interior space within the conduit, the wall having a means for securing a retainer in a selected position relative to the opening, (ii) a catheter positioned coaxially within the conduit, the catheter having a catheter wall, and (iii) the retainer removably secured within the opening wherein a tooth of the retainer penetratingly positioned within the catheter wall.
US08652102B2	Colonic cleansing device The present invention may provide devices suitable for insertion into a body passage. The devices may include a conduit and a distal head region located at the distal end of said conduit. A plurality of apertures on the surface of said head region and conduit may be used to direct a liquid spray outwards from said device. The apertures may be designed and spatially arranged such that when the device is inserted into a body passage, the liquid spray emitted from said apertures may be capable of both reducing the frictional contact between the device and the walls of said passage and of cleansing said passage of undesired solid and other particulate matter.
US08652092B2	Applicator The invention relates to applicators (1) for implantation of an implant, having a cylinder (2) and a plunger (3) displaceably mounted therein, which plunger (3) has a pusher plunger (31) for pushing the implant out of a cannula, the cannula being mounted on a cylinder part, the cylinder part (4) being movably guided in the cylinder (2), there being provided a gear mechanism (5) which couples the plunger (3) to the cylinder part (4), a movement of the plunger (3) relative to the cylinder (2) being converted into an opposite movement of the cylinder part (4).
US08652088B2	Method for use of microdialysis Very accurate measurements of mass transfer can be made rapidly by permitting diffusion of an agent desired to be measured into or out of a small, very precisely known volume of a microdialysis probe, then rapidly pumping or flushing (“pulsing”) the probe with a known volume of fluid as a single pulse. The diffusion and pulsing may be repeated. The method, hereinafter called pulsatile microdialysis (PMD) to distinguish it from prior art continuous flow microdialysis, is useful for measurements in a number of processes, including protein binding, adsorption to binding agents such as activated charcoal, release from microemulsion drug delivery systems, determination of drug diffusion coefficients and concentrations, and for various other purposes.The method is based on mathematical manipulation of Fick's Laws. Resulting equations were verified against experimental data using methazolamide, warfarin and benzocaine as test drugs.
US08652086B2	Systems and methods for power and flow rate control The invention is generally directed to systems and methods for fluid control, and more particularly to systems and methods for power and flow rate control for aspiration. In accordance with one embodiment, an aspiration system includes an aspiration line having distal and proximal ends and an aspiration port defined in the distal end; a fluid transport device operatively coupled to the proximal end of the aspiration line; and a flow restrictor operatively coupled to the aspiration line in between the fluid transport device and the aspiration port. To measure occlusion within the line, first and second pressure sensors are utilized, the first sensor being operatively coupled to the aspiration line between the port and the restrictor and the second sensor being operatively coupled to the aspiration line between the restrictor and the fluid transport device. The pressure differential between the two sensors can provide an indication of the onset, presence, and/or elimination of an occlusion.
US08652083B2	Anti-obesity stent The anti-obesity stent includes a tubular structure having outer and inner surfaces and proximal and distal ends. The tubular structure is sized to fit within a duodenum in substantially coaxial relation therewith. The tubular structure is impervious or semi-permeable to digestive substances and chyme within the duodenum. The anti-obesity stent includes a transport structure at least a part of which is coincident with or connected to the outer surface. The transport structure extends to the distal end of the tubular structure. At least one retainer structure is connected to the tubular structure. The retainer structure secures the tubular structure within the duodenum such that the transport structure is positioned to receive digestive fluids from a papilla of Vater on an inner surface of the duodenum. The transport structure provides a conduit for the digestive fluids therein to flow to the distal end.
US08652082B2	Blood treatment apparatus A proposed blood treatment apparatus includes: a blood treatment unit, at least one fluid pump and at least one blood pump. The blood treatment unit is configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid. The fluid pumps are configured to pass blood treatment fluid through the blood treatment unit. The blood pumps are configured to extract untreated blood from a blood source, pass extracted blood through the blood treatment unit and deliver treated blood to a target vessel. Additionally, at least one of the fluid pumps is configured to control the operation of at least one blood pump via the blood treatment fluid. Moreover, at least one of the blood pumps is integrated into a joint apparatus element, which includes the blood treatment unit. Thus, this blood pump and the unit may be mounted as well as be discarded jointly.
US08652080B2	Apparatus and method of use for a wrist extension brace An apparatus and method of use for a wrist extension brace, intended to be used to position, secure, stabilize, and extend a patient's wrist for the purpose of assisting cannulation of blood vessels in the wrist and forearm. The apparatus generally includes a frame having a fixed dorsiflexion angle and means for cushioning a patient's hand, wrist and forearm and means of attaching such to the wrist extension brace. The method of use includes the steps of attaching the apparatus to a patient's wrist and adjusting it after such attachment.
US08652079B2	Compression garment having an extension A compression garment for applying compression therapy to a wearer's body including a compression sleeve having a proximal edge and a distal edge. The sleeve includes at least one bladder. A tube is attached to the bladder. A connector on the tube connects the tube to a source of compressed fluid for inflating the bladder. The distal edge of the compression sleeve has a first portion and a second portion jutting distally from the first portion.
US08652077B2	System and method for determining depth of chest compressions Systems and methods for determining depth of compressions of a chest of a patient receiving chest compressions. A field detector is used having at least two coils at a fixed distance from each other.
US08652073B2	Parameters for an ultrasound device comprising means to generate high intensity ultrasound beam The present invention relates to a device for treatment of an ocular pathology, the device comprising at least one eye ring wherein the proximal end of said eye ring is suitable to be applied onto the globe and means to generate ultrasound beam fixed on the distal end of the eye ring, said means to generate ultrasound beam presenting a concave segment shape conformed along a single curvature corresponding to a single direction wherein the concavity is designed to be tuned towards the eyeglobe.
US08652070B2	Systems, devices, and methods for interpreting movement According to some exemplary embodiments, a method or system can involve associating a plurality of biokinetographic comparison results with a first specific dysfunction from a group of specific dysfunctions, each of the biokinetographic comparison results obtained from a comparison of a biokinetographic value to a standard for a corresponding biokinetographic variable.
US08652069B2	Apparatus including a lancet Apparatus for eliciting a blood sample comprises: a member rotatably mounted on a shaft and configured to rotate between a first position and a second position; and a curved lancet protruding from the member and configured to co-rotate with the member such as to provide skin penetration by the lancet when the member is in the second position. At least 1 mm of the end portion of the curved lancet is coincident with a line that is concentric with respect to the shaft.
US08652068B2	Integrated sensor for analyzing biological samples An integrated lancet and testing striplet for measuring a body analyte level in a health care regimen includes a skin piercing member and an analyte sensor coupled together.
US08652064B2	Sampling circuit for measuring analytes This disclosure describes an apparatus and method for measuring analytes in exhaled air. The device contains an inlet through which exhaled air is received. A tube, having a number of different paths running throughout the device, is coupled to the inlet which enables the exhaled air to be re-circulated through the device. At least one portion of the tube is configured in a non-linear fashion. This particular portion of the tube may be used to temporarily store a sample of the exhaled air. The device also contains a converter configured to partially convert an analyte in the exhaled breath from a first state to a second state as the exhaled air is being re-circulated. An analyte sensor is also included to measure the levels of the converted analyte in the exhaled breath.
US08652063B2	Non-invasively measuring physiological process Equipment (10) for non-invasively measuring a physiological process includes at least one receiver (12) to be placed relative to a body of a subject being examined to detect at least one signal from the body of the subject. A discrimination unit (20.1) determines if the at least one signal is a signal of interest associated with the physiological process. A processor (20) processes the signal of interest to enhance the signal of interest and suppresses other received signals that are not of interest.
US08652058B2	Blood vessel pressing cuff, blood pressure measuring apparatus including the blood vessel pressing cuff, and blood pressure measuring method using the blood pressure measuring apparatus A blood vessel pressing cuff includes a strap surrounding a body part, a first actuator disposed on the strap and including a first shape memory alloy which changes to a first shape memorized in advance, at a temperature equal to or higher than a first temperature, and a second actuator disposed on the strap and including a second shape memory alloy which changes to a second shape memorized in advance, at a temperature equal to or higher than a second temperature that is different from the first temperature. If the first shape memory alloy changes to the first shape, pressure applied to the body part surrounded by the strap is increased. Even when the first shape memory alloy changes to the first shape, if the second shape memory alloy changes to the second shape, the pressure applied to the body part surrounded by the strap is reduced.
US08652052B2	Biologic information detecting apparatus In measurement requiring application of pressure to a tissue of a living body such as blood pressure measurement, noise due to vibration tends to occur. It is difficult to accurately measure a pulse wave and a blood pressure value. It is also difficult to measure blood pressure in life activities or to measure blood pressure at intervals or continuously where a tonometer is always attached. There is consequently a problem of holding a biologic information detecting apparatus. The present invention solves the problems by providing an easy-to-wear biologic information detecting apparatus for stably detecting biologic information. The biologic information detecting apparatus includes a sensor for detecting biologic information in a pair of arms connected via a spindle, and the sensor is tightly attached to a projecting part in a living body, particularly, a tragus of an auricle.
US08652049B2	Ultrasonic diagnostic apparatus According to one embodiment, an ultrasonic diagnostic apparatus comprises an ultrasonic probe, an ultrasonic transmission/reception unit, an echo processing unit configured to generate complex data based on the echo signals, a phase shifting unit configured to shift a phase of each ensemble data constituted by N complex data associated with the same depth on the same ultrasonic raster in accordance with a reference phase, an interpolation processing unit configured to interpolate ensemble data associated with an interpolated raster between adjacent ultrasonic rasters based on the phase-shifted ensemble data, and an image data generation unit configured to generate image data based on the phase-shifted ensemble data and the interpolated ensemble data.
US08652046B2	Palpation algorithms for computer-augmented hand tools A method and system for performing minimally invasive tissue examination with a computer-assisted hand tool. The computer-assisted hand tool is moved into contact with the tissue under examination. An indication is received from a first sensor in the computer-assisted hand tool of each feature detected in a time interval during movement of the hand tool in contact with the tissue under examination. Each feature detected in the preset time interval is processed to determine a haptic feedback to provide to the user. A haptic feedback is generated and provided to the user via an actuator that is responsive to at least one feature detected in the time interval.
US08652045B2	System and method for characterizing tissue based upon homomorphic deconvolution of backscattered ultrasound A system and method are disclosed that facilitate characterizing vascular plaque tissue based upon spectral analysis of intravascular ultrasound echo signal segments. In particular, a power spectrum analysis of an integrated backscatter parameter renders a set of characterizing parameter values based on received intravascular ultrasound echo signal segments. The resulting parameter values are applied to plaque tissue characterization criteria to render a plaque tissue characterizations for regions of interest. The system and method include computer-executable instructions performed on a computing device to render an estimate of a system transfer function using a homomorphic deconvolution technique.
US08652042B2	Sensing moisture level of human skin A human skin moisture measuring device having an interdigitated resistive sensor formed on a plate-like transparent support is described, with a face designed to be placed into contact with the skin to be subjected to the moisture degree measurement. The device further comprises image sensing means turned towards the opposite face of the support and a lighting device arranged sideways relative to the support to direct the light radiation in the support at a prefixed angle. Means for processing the signal coming from the interdigitated resistive sensor and from the image sensing means give as output a value of the measured moisture degree that is normalized with respect to the actual surface of contact between skin and sensor.
US08652041B2	Systems and methods for assessing equipment operator fatigue and using fatigue-risk-informed safety-performance-based systems and methods to replace or supplement prescriptive work-rest regulations In a system and method for assessing and modifying fatigue, an input device receives current work-rest pattern and/or sleep data from an individual. A data aggregation and processing platform combines the current work-rest pattern and/or sleep data with previous data related to the individual to generate a fatigue assessment result, a diagnostic assessment result, and a corrective intervention result. At least one output display outputs the fatigue assessment result, diagnostic assessment result and corrective intervention result in a user-readable format to a user. The user uses this information to revise the work-rest pattern to reduce or control future fatigue risk.
US08652040B2	Telemetric apparatus for health and environmental monitoring Wearable apparatus for monitoring various physiological and environmental factors are provided. Real-time, noninvasive health and environmental monitors include a plurality of compact sensors integrated within small, low-profile devices, such as earpiece modules. Physiological and environmental data is collected and wirelessly transmitted into a wireless network, where the data is stored and/or processed.
US08652038B2	Health monitoring appliance A heart monitoring system for a person includes one or more wireless nodes; and a wearable appliance in communication with the one or more wireless nodes, the appliance monitoring vital signs.
US08652037B2	Data collection system and interface A data collection system is formed from an analyte detection meter and a base station. The meter and the base station are operatively connected to one another to transfer data from the meter. The base station is able to communicate transferred data to a data receiving server, and the transfer of data occurs in response to a defined stimulus such as the proximity of the meter and base station or an alarm set at a predetermined time of day. The data collection system can be used in combination with a system interface that provides a data management system (DMS) resident on a device such as a personal computer. The DMS can recognize a particular meter and may incorporate into the displayed information not only the data resident on the meter but also information previously transferred from the meter. The DMS may be launched on the computer as soon as connection with a meter is detected. The DMS may also reproduce the display of the particular meter on the display of the computer such that the user need only learn one set of controls. Changes to the setting of the meters may be accomplished through the computer and an update transferred and stored on the connected meter.
US08652033B2	Video stylet with directable tip A video intubation system that provides for multiple image streams to be simultaneously presented to a user, the first image stream generated by a video laryngoscope and the second image stream generated by a video stylet. The video stylet is provided with a deflection section for ease of introducing an ETT into the trachea of a patient, the video stylet having a pistol-type grip and a control interface in the form of a trigger-type lever to facilitate comfortable griping and manipulation by the user.
US08652032B2	Plug body and endoscope A forceps plug includes a tubular plug main body, and a tubular fixing member rotatably held on the outer periphery of the plug main body. The inner peripheral surface of the fixing member is provided with a pair engaging claws. A ratchet mechanism that allows the fixing member to move to an incorporated location, an attachment position, a fixed position, and a removal position in order, but stops further movement to a position where the fixing member has moved once is provided between the inner peripheral surface of the plug main body and the outer peripheral surface of the fixing member. Since the fixing member of the used forceps plug removed from a opening is stopped from being to the fixed position by the ratchet mechanism, the fixing member cannot be fixed to the opening. Reuse of the used forceps plug can be made impossible without being accompanied by destruction.
US08652029B2	Intelligent endoscope systems and methods Endoscope sheaths and associated endoscopy data collection and analysis systems and methods are described. In one implementation an endoscope sheath include a body and one or more sensors disposed in the body. The sheath may further include a leak detection apparatus configured to detect leaks in the sheath body. In addition, the sheath may include actuator apparatus, such as a balloon catheter or other surgical instrument. Data from the endoscope and endoscope sheath may be collected, fused and displayed for use in medical procedures and/or analysis.
US08652025B2	Methods and devices for diastolic assist The devices and method described herein allow for therapeutic damage to increase volume in these hyperdynamic hearts to allow improved physiology and ventricular filling and to reduce diastolic filling pressure by making the ventricle less stiff. For example, improving a diastolic heart function in a heart by creating at least one incision in cardiac muscle forming an interior heart wall of the interior chamber where the at least one incision extends into one or more layers of the interior heart wall without puncturing through the interior heart wall and the incision is sufficient to reduce a stiffness of the interior chamber to increase volume of the chamber and reduce diastolic filing pressure.
US08652024B1	Sterilizable cable system for implantable blood pump A implantable blood pump system includes a pump unit, a first percutaneous cable section, a control unit, and a second cable section connecting the control unit to the first cable section. All components except the control unit are sterilized. The connection between cable sections is removable. The connection between the control unit and second cable section is unremovable once it is assembled. The second cable section has a length sufficient to place an end outside of the sterile field for mating with the control unit during implantation.
US08652023B2	Health applications of a double helix conductor An electrical system having an underlying structure resembling the double helix most commonly associated with DNA is used to produce useful electromagnetic fields for health applications and/or medical applications.
US08652020B2	Guide nozzle for use with filter rod manufacturing apparatus A guide nozzle (112) for use with an apparatus (110) for the manufacture of filter rods for smoking articles. The guide nozzle comprises a support member (130) configured to be fixed relative to said apparatus for the manufacture of filter rods, a funnel (120) through which loose filter material is propelled, mounted to the support member and, an adjuster (140) mounted between the support member and the funnel to enable the relative position of the funnel and the support member to be adjusted to control the direction of flow of loose filter material propelled through the funnel. An apparatus for the manufacture of filter rods for smoking articles having such a guide nozzle, and a method of manufacturing a filter rod using the same.
US08652017B2	Ring saw cutting device A device for cutting tubular and rod-shaped work pieces using the whirling method includes a whirling unit on which a holder mounted so as to rotate, connected with a drive, for a saw blade having internal teeth is disposed. The holder and saw blade are provided with corresponding reference mechanisms for fixation of the saw blade in a defined position. The device also includes a mechanism for automatic replacement of the saw blade. A saw blade having internal teeth is also provided for use in this device. The saw blade has at least two indexing bores and at least two gripping openings, which are disposed offset relative to one another.
US08652016B2	Collapsible and expandible exercise weight A collapsible exercise weight comprises a first end wall portion, a second end wall portion and a peripheral outer wall that together define a substantially hollow interior. A capped aperture permits the ingress of water into and the egress of water from the substantially hollow interior. A handle connector is for connecting the collapsible exercise weight to a handle. The peripheral outer wall comprises a plurality of wide diameter bellows folds and a plurality of narrow diameter bellows folds disposed alternatingly one with the other. The wide diameter bellows folds and the narrow diameter bellows folds are each movable between an expanded configuration and a collapsed configuration. The narrow diameter bellows folds at least partially fit within adjacent ones of the wide diameter bellows folds when the narrow diameter bellows folds are in the collapsed configuration.
US08652011B2	Frame structure for a safety enclosure for a recreational structure A frame structure for a safety enclosure for a recreational structure includes at least one substantially rigid horizontal support member, at least one vertical pole member having a top end, a substantially vertical portion and portion that is not substantially vertical, and at least one end cap member. The end cap member mates with the top end of the vertical pole member and releasably receiving a horizontal support member. In one exemplary embodiment, the vertical pole member can be part of a safety enclosure. In another exemplary embodiment, at least one horizontal support member is flexibly rigid. One exemplary embodiment provides a netting-type material that is attached to one of a horizontal support member and an end cap member, such that the netting-type material forms a substantially cylindrical shaped safety enclosure space.
US08652008B2	Power transmission apparatus A power transmission apparatus mounted on a vehicle is provided with a motor that transmits power from the motor to an axle through a friction engagement element. The power transmission apparatus is further configured with a mechanical pump that pressure-feeds a fluid to a fluid pressure servo for the friction engagement element, and an electric pump that pressure-feeds the fluid to the fluid pressure servo of the friction engagement element. Furthermore, a lubrication supply passage is configured to connect to a flow passage extending from the electric pump to the fluid pressure servo. A first valve switches between opening and closing the lubrication supply passage such that, during a stop of the motor, so as to supply the fluid to the fluid pressure servo when in a driving position, and to the component to be lubricated when shifted to a neutral position.
US08652006B2	Method and apparatus for operating a powertrain system upon detecting a stuck-closed clutch A powertrain system includes a multi-mode transmission having a plurality of torque machines. A method for controlling the powertrain system includes identifying all presently applied clutches including commanded applied clutches and the stuck-closed clutch upon detecting one of the torque-transfer clutches is in a stuck-closed condition. A closed-loop control system is employed to control operation of the multi-mode transmission accounting for all the presently applied clutches.
US08652002B2	Method of operating a torque converter clutch A method of operating a torque converter clutch in an engine start-stop vehicle improves launch after an auto stop event. During the autostop event, hydraulic fluid is supplied to the torque converter clutch operator through one or more solenoid valves by an auxiliary electric pump. When the prime mover is started at the conclusion of the autostop event, the torque converter clutch is thus locked, assuring rapid and sufficient torque transfer through the torque converter to the transmission and improved acceleration during vehicle launch. As the vehicle accelerates, the hydraulic pressure in the clutch operator is reduced and slip through the clutch increased to achieve a smooth launch and return to conventional torque converter operation.
US08651999B2	Driving device A drive device has an internal combustion engine, a first electrical machine, and a second electrical machine. The first electrical machine is at least indirectly connectable to the internal combustion engine. In addition, the drive device has an output which is at least indirectly connected to an output shaft. According to the invention, a switching device is provided, using which, in a first state, the internal combustion or the first electrical machine is connectable to the output shaft or, in a second state, the second electrical machine is connectable to the output shaft.
US08651997B2	Planetary gear reducer In a planetary gear device, a first side plate as carrier is formed to a disc plate shape and secures thereto pins to protrude the pins from one end surface in an axial direction. The outside diameter of the first side plate is formed to be a small diameter on one side in the axial direction and a large diameter on the other side in the axial direction. The first side plate is provided with press-fitting hole portions with the pins press-fitted thereinto and small-diameter side concavities that are formed on the press-fitting hole portions on one side in the axial direction, that open to one end surface in the axial direction of the first side plate and that have internal surfaces being out of contact with the pins at at least parts thereof.
US08651992B2	Speed reducer, robot hand and robot Through holes are formed in a revolving gear which revolves while being engaged with a ring gear, and penetration pins are inserted in the through holes. An elastic member having a circular ring shape, which is formed so that an inner diameter thereof can move with respect to an outer diameter thereof, is mounted to either an inner circumferential surface of the through hole or an outer circumferential surface of the penetration pin. Thus, the through hole and the penetration pin do not interfere with each other, and thus, it is possible to set a small clearance between the through hole and the penetration pin to such a degree, while preventing a speed reducer from being in a locked state due to interference. As a result, it is possible to suppress a backlash between the through hole and the penetration pin.
US08651987B2	Orientation system and method A system and a method for orientation of a ring by rotation, including a cable engaging the ring which rotates about a ring axis, a motor assembly providing a first rotation reduction, and a stretcher for stretching the cable. The system has at least one proximal pulley and at least one distal pulley rotating about a pulley axis each pulley having grooves configured for receiving the cable therein. The ring is rotated by the motor assembly and the pulley assembly is configured to provide a second reduction of rotation to the ring relative to motor rotation, whereby the ring is driven via at least a double reduction of rotation relative to rotation of the motor, and the cable, the plurality of pulleys, and the ring provide a one-way mechanism.
US08651985B2	Racket frame A racket frame 2 includes a head 4, a shaft 8, and a pair of throats 6 extending from the head 4 to the shaft 8. A flexural rigidity G15 of the throats 6 in a low load range (from 5 kgf to 15 kgf) is equal to or greater than 600 kgf/mm but equal to or less than 900 kgf/mm. A flexural rigidity G55 of the throats 6 in a high load range (from 45 kgf to 55 kgf) is equal to or greater than 900 kgf/mm but equal to or less than 1200 kgf/mm. A rigidity ratio (G15/G55) of the flexural rigidity G15 and the flexural rigidity G55 is equal to or greater than 0.70 but equal to or less than 0.85.
US08651984B2	Climate variable lacrosse heads and related methods of use A first lacrosse head constructed from a first material having first properties or a second lacrosse head constructed from a second material having second properties is selectively used in lacrosse activities, based on environmental conditions, such as temperature, humidity and/or solar activity, to provide generally consistent head performance as perceived by a lacrosse player across a range of environmental conditions. The first and second heads can be identical in structure, but constructed from different materials. For example, the first head can include a polyamide, optionally, Nylon 6,6 polyamide, and the second head can include a high performance polyamide resin, optionally a polypthalamide. An environmental indicator that provides visual and/or audible output with regard to environmental conditions can be included with at least one of the first head, the second head and a shaft to which the heads can be joined. Related methods of use are also provided.
US08651983B2	Swing game A swing ball game has a top support frame member. A swing hangs from the top support frame member. The swing has a swing seat configured to swing in a front and rear direction. At least one vertical support frame member is connected to the top support frame member and supports the top support frame member. A rocker support frame member has a rocker bottom profile. The vertical support frame member is connected to the rocker support frame member. The rocker support frame member is oriented sideways so that the top support frame member can rock in a left and right direction.
US08651975B2	Golf club head with stiffening and sound tuning composite member A golf club head with sound tuning composite members forming at least a portion of the surface of the golf club head is disclosed herein. The composite members being a composite layer made out of a sandwiched core layer that is interposed inside the midsection of the composite member to provide vibration damping and sound tuning characteristics.
US08651974B2	Aerodynamic golf club A “Aerodynamic Golf Club Assembly” is designed for a minimal amount of air resistance to the face of the club head when it's in a forward swing mode. This allows the golfer to swing the club head at a higher speed, which will cause the ball to travel a longer distance. This is done by means of one or more fore and aft straight round holes that protrude from the face of the head through the hill of the head. The hill of the head has a concave surface, so a stronger vacuum is created during a forward swing mode of the head.
US08651973B2	Golf club with wind resistant shaft and golf club head Golf club, golf club shaft and golf club head structures are presented. The golf club may include a shaft having a core and an airfoil shaped skin substantially surrounding the core and in contact with the core. The golf club may further include a golf club head having a plurality of apertures formed in a front face of the golf club head and extending through an interior of the golf club head to a rear portion of the golf club head. The apertures may narrow or widen as they extend from the front face to the rear portion.
US08651972B2	Artificial sport log A lightweight, portable artificial sport log having physical properties that mimic a selected natural log is disclosed that has a hollow cylindrical shell of a suitable polymeric material defining a volume having the desired dimensions of length and diameter of a selected natural log of interest, an internal baffle support shape of a rigid polymeric foam material is fixed to said internal surface of said cylindrical shell, end closure members at ends of said hollow cylindrical shell provided with sealable fill/discharge openings for adding and draining water from the artificial log. The internal baffle volume and shape are determined such that the buoyancy of the artificial log generally equals the buoyancy of the natural log of interest and the mass moment of inertia resembles that of the natural log of interest when the artificial log is filled with water.
US08651966B2	Coupling apparatus with two couplings A coupling apparatus for transmitting torque from a drive shaft to an output shaft includes two couplings with a respective primary part and secondary part. The primary and secondary parts are twistable to a certain extent relative to one another against the force of springs. Several carriers for carrying spring plates and support plates are arranged in a distributed manner over the circumference of the coupling. There is a locating pin between two screws for positioning a carrier, the locating pin being axially parallel to the screws. One coupling is in a drive connection with the drive shaft, and the other coupling is in a drive connection with the output shaft. Every carrier which can be inserted into a respective recess in the primary part or secondary part of the respective coupling forms a premounted spring unit together with the spring plates carried by the carrier.
US08651964B2	Advanced video controller system A video control system has an accelerometer sensor connected to a microcontroller for imparting motion and orientation information to the microcontroller. An encoder/transmitter is connected to the microcontroller and converts a plurality of parallel signals from the microcontroller into a serial data stream which is wirelessly transmitted to a receiver/decoder which converts the serial data back to the original parallel signals. The receiver/decoder is connected to a keyboard encoder that is connected to the keyboard port of personal computer. The accelerometer sensor, microcontroller and encoder transmitter are adapted to be worn on a video player's person. The system allows for a realistic experience in a video environment in which movement of the video player is replicated and appreciated on a video screen.
US08651960B2	System, method and computer program for enabling an interactive game A system, method and computer program enable an interactive game. A game server, in response to a user request, provides a unique identifier associated with an instance of the interactive game. The game server forwards one or more invitations to join the interactive game in accordance with the user request. Thereafter, the game server registers one or more wireless communication devices to be used as data controllers for use by participants that join the game.
US08651959B2	Presenting and controlling wagering game marketing information Described are one or more embodiments that include a browser application (“browser”) with multiple parts. A first part of the browser (e.g., a toolbar, a dropdown, a pop-up, a widget, etc.) presents first content associated with one or more wagering games. Concurrently a second part of the browser (e.g., a main content display area) presents second content independently from presentation of the first content in the first part of the browser. In some embodiments, the first content and second content are from separate content providers with a marketing relationship. In some embodiments, in response to concurrent presentation of the first and second content, the browser application detects the marketing relationship between the content providers and presents one or more indicators. The one or more indicators indicate the marketing relationship. For example, the indicators can indicate cross-marketing, available coupons, and/or awards available via the first or second content.
US08651957B2	System and method for fantasy sports gambling A method and system for providing an interactive gaming system is disclosed. At least one interactive social gaming community allows a plurality of users to engage in a wagering contest against a single entity. An initial amount of gaming units associated with an initial user investment is allocated to each user. A payout table is dynamically generated and includes at least one threshold amount of gaming units associated with rewards available to the user. A bet request signal received from a user is automatically reconciled with an outcome of at least one type of contest occurring during an active gaming period. A user account is updated by modifying an amount of gaming units in a user account based on a result of the at least one type of contest and determines if user has earned the reward associated with the at least one threshold.
US08651956B2	Method and system for instant-on game download Disclosed are methods, apparatus, and systems, including computer program products, implementing and using techniques for a method for providing a game on demand over a data network, in a gaming machine. The gaming machine sends a request message for a game application over the data network. In a network mode, the gaming machine receives outputted results from an executed game application over a streaming channel of the data network for network-based game play. During the network-based game play, the game application is downloaded over a download channel of the data network. In a local mode, the gaming machine executes the downloaded game application independent of the network-based game play. The gaming machine switches instantaneously from the network mode to the local mode for machine-based game play, including maintaining a status of the network-based game play.
US08651955B2	Game device, control method, and computer program product A game device includes a packet processing section that processes a packet that is transferred between the game device and another game device via a network, a game calculation section that performs a game calculation process based on data transferred using a packet, and an image generation section that generates an image based on a result of the game calculation process. The game calculation section performs a game sequence process as the game calculation process in each game sequence interval. A packet that is transferred between the game device and the other game device includes a packet ID that specifies the type of data transferred using the packet, and an interval ID that specifies the game sequence interval that utilizes data transferred using the packet. The packet processing section compares the interval ID included in a received packet with the interval ID of a current game sequence interval. The game calculation section performs the game calculation process based on data included in a packet when the interval ID included in the packet coincides with the interval ID of the current game sequence interval.
US08651948B2	System and method for generating customized odds bet for an event A system for managing bets comprises a memory and a processor. The memory stores information associated with a field of participants for an event, each participant associated with particular odds for the event. The processor receives a bet that a lead participant from the field of participants will finish in a particular subset of finishing positions in the event, wherein the bet is associated with customized odds. The processor further select one or more additional participants from the field of participants to add to the bet such that the odds associated with the lead participant combined with the odds associated with the one or more selected additional participants at least approximates the customized odds for the bet.
US08651946B1	Coin-out gaming reward system A gaming system including one or more gaming machines, wherein the gaming system monitors the coin out of the gaming machines and triggers a system game award to one or more gaming machines based upon a predetermined criteria that includes the coin out value.
US08651944B1	Electronic gaming device with scrape away feature Examples disclosed herein relate to systems and methods, which may receive wagers. The systems and methods may include scrape away functionality.
US08651936B2	Keno game with rearranging symbols A wagering game is played on an electronic system with a processor, a video display screen and a player input system. The processor recognizing a wager, enabling player input at the specific player position. The processor executes code to display a grid of at least 50, preferably at least 80 frames for display of a unique symbol within each frame of the grid. The processor compares recognized at least three symbols at the specific player position with at least 10 symbols selected by the processor. The processor displays a first arrangement of unique symbols within each frame prior to recognizing selection at the specific player position, and B) the processor displays a second arrangement of the same unique symbols after recognizing selection at the specific player position, the first arrangement of symbols being different from the second arrangement of symbols with respect to distribution of symbols among the frames.
US08651933B2	System for playing a game of skill A system for playing a game of skill with rules fashioned on those of poker using one suit of a standard deck of playing cards. The system is adapted to allow a plurality of players to compete against one another. Each player is provided a screen with the same hand of face-up cards simultaneously. The cards in each hand are of the same suit. Each card is arranged within a circular configuration in sequential numerical and/or value order. The system deals each player a previously unknown and not predetermined initial set of cards as each other player and allows each player to change any one or more of his cards in sequential numeric/value order, up or down. Each single step up or down to change a card is considered a step and a predetermined total number of steps is allowed to attempt to achieve the best poker hand.
US08651931B2	Video poker system and method An electronic video poker machine configured to allow play of a defined series of hands of video poker. The electronic video poker machine comprises at least one display device, at least one input device, a memory and at least one computer processor configured to display at least a first hand and at last one subsequent hand of at least three cards. A player is provided a first hand of cards on the display. The player identifies which cards from the hand to hold using the input device. The remaining cards from the hand are discarded and draw cards are dealt to replace the discarded cards. The discarded cards are returned to the deck after the draw, making those discarded cards available for subsequent hands in the defined series of hands.
US08651927B1	Combine harvester sieve assembly with an integrated air cleaning system A combine harvester that employs a sieve assembly having a frame structure with movement that facilitates pressurizing an air supply connected thereto. Various aspects of the subject disclosure provide for sieve elements having internal air passages that are supported in the frame structure. A plurality of pressurized air ports are disposed along the frame structure or sieve elements and are oriented at an angle so as to direct pressurized air upwardly through the sieve elements. The pressurized air supply is in communication with the air ports.
US08651922B2	Inline handheld power tool A powerhead for a hand held power tool includes a powerhead assembly, the powerhead assembly being operably couplable to a hand held motive source, the powerhead assembly having a rotatable implement, the implement being selectively rotated by the motive source when the motive source is operably coupled to the powerhead assembly, the implement further being rotatable about an implement axis, the implement axis being disposed transverse to a powerhead assembly longitudinal axis, the implement axis intersecting the powerhead assembly longitudinal axis. A hand held power tool and a powerhead of forming a powerhead for a hand held power tool are further included.
US08651921B2	Surface treatment device A surface treatment device includes an enclosure which has an opening through which the leading edge of an aerofoil passes. A sealing element is provided on the enclosure to seal the device to the surfaces of the aerofoil. An abrasive is located within the enclosure and two fluid openings are also provided through which a chemical accelerant can be pumped. In operation the enclosure is oscillated relative to the component so that material is abraded. Whilst the enclosure is oscillated a chemical accelerant is simultaneously pumped through it. The device allows for the local application of a surface treatment on a component.
US08651919B2	Adhesive sheet and process for manufacturing electronic part An adhesive sheet comprising a sheetlike base material and, superimposed on one major surface thereof, an adhesive layer, wherein the average surface roughness on one major surface of the base material is in the range of 0.1 to 3.5 μm and on the other major surface thereof is in the range of 0.05 to 0.7 μm. In this structure, the average surface roughness values on both the major surfaces of the base material as a constituent of the adhesive sheet are regulated so as to fall within respective specified ranges, so that not only can any blocking occurring in backwinding of reeled adhesive sheet be inhibited but also any occurrence of minute unevenness (waving) on the wafer surface after grinding can be inhibited, and further that the transparency of the adhesive sheet can be maintained.
US08651916B2	System and method for generating realistic eyes Realistic electronically controlled eyes for a figure such as a doll, toy, animatronic being, robot, etc., are provided by displaying a sequence of images simulating eye movement on an electronic display screen mounted to a portion of the figure. A convex lens, which serves to simulate the figure's eye, is mounted substantially in contact with a surface of the display screen system from which the light defining the sequence of images is emitted. To an observer looking at the convex surface of the lens, the lens appears as an eye characterized by realistic eye movement.
US08651912B2	Organic EL element, method for manufacturing the same, and organic EL lighting apparatus An anode 2 is formed on an element substrate 1. By using a film-forming solution containing a stacking material that forms an organic layer 43, a film is formed on a donor substrate 10 to form a transfer layer 11, thereby fabricating a transfer substrate 12. The transfer substrate 12 and the element substrate 1 are placed so as to face each other with spacers 13 interposed therebetween, such that the surface of the transfer substrate 12, which has the transfer layer 11 formed thereon, faces the element substrate 1 having the anode 2 formed thereon. The transfer substrate 12 and the element substrate 1 facing each other are held under vacuum conditions. The transfer substrate 12 is heated by the heat source 15 under the vacuum conditions to transfer the transfer layer 11 to the element substrate 1.
US08651908B1	Anti-ingestion system for a marine drive An anti-ingestion system is provided for a marine drive with a submerged exhaust outlet. An anti-ingestion valve is operated by differential pressure thereacross to a closed condition when the engine is operating in an on state and cooling water is being pumped through a water conduit to an exhaust mixing point, with the anti-ingestion valve blocking passage of cooling water therepast in the noted closed condition. The anti-ingestion valve is operated by differential pressure thereacross to an open condition when the engine is in an off state, and permits passage of air therethrough and communicates atmospheric pressure through the water conduit to the exhaust mixing point to relieve vacuum in the exhaust system.
US08651907B2	Water jacketed marine exhaust components having multiple stream spray ring configurations A water jacketed exhaust component includes an exhaust pipe having a radially inwardly tapered tail end, a water jacket disposed in surrounding relation with the exhaust pipe, and a generally V-shaped spray ring. The spray ring includes a first and second set of apertures that create diverging streams of cooling water. A first set of apertures creates an annularly disposed series of streams that are directed downstream and radially inward. These streams are generally directed toward the outer surface of the exhaust pipe structure which extends downstream of the spray ring. A second set of apertures creates an annularly disposed series of streams that are directed downstream and radially outward. These streams are generally directed toward the inner surface of the water jacket structure extending downstream of the spray ring. By providing a water jacketed exhaust component with a spray ring that creates diverging streams of cooling water, the present invention provides a water jacketed marine exhaust component that provides improved exhaust gas cooling over a wider range of engine operating conditions. An alternate embodiment includes a V-shaped spray ring configured to create converging streams of cooling water.
US08651906B1	Outboard motors and apparatuses for intake of air to outboard motors An apparatus for intake of air to an outboard motor includes an inlet receiving a mixture of air and water from atmosphere surrounding the outboard motor and an outlet discharging the air. A conduit extends between the inlet and the outlet. The conduit has a vertically downwardly oriented first flow path, a vertically upwardly oriented second flow path, and a junction joining the first and second flow paths. The junction is oriented with respect to the first and second flow paths such that both centrifugal and gravitational forces separate the water from the air as the mixture flows therethrough.
US08651902B2	Wire-grasping structure for terminal block A wire-grasping structure for a terminal block is disclosed. The wire-grasping structure includes a core, a conductive terminal piece and a screw. The core is transversely formed with a socket and vertically formed with a threaded hole. The socket and the threaded hole are communicated mutually and each communicated with the exterior of the core. The conductive terminal piece has a receiving portion and a terminal portion. The terminal portion is configured to be horizontally inserted into the socket such that the receiving portion projects from the core terminal portion. The screw is configured to be vertically screwed in to the threaded hole and enter the socket to abut against the terminal portion. Thereby, the wire-grasping structure can store a jumper bar and facilitate convenient use.
US08651895B2	Integral connector for programming a hearing device For the connection of a programming device to a hearing device an insertable plate (21) into the casing or frame of the hearing device is provided, comprising on one side contacts (29) to the hearing device electronics and on the other side contact pins (27), provided for the connection of a contact adapter/cable system of the programming device.
US08651892B2	Visual mating detector for electrical connector The present disclosure describes a system for connecting two connectors to each other. The system includes a first connector having a first connector surface, and the first connector surface includes a transparent shape. Further, a second connector, having a second connector surface, includes a portion that includes a second connector color. Particularly, the second connector is configured to be inserted into the first connector, enabling a superimposition and alignment of the transparent shape with the portion of the second connector surface, thereby visually indicating a valid connection between the two connectors.
US08651891B2	Hot line clamp A hot line clamp employs a pair of jaw members which have clamp surfaces. The jaw members are coupled under the load of a compression spring. One jaw member has a ring which allows for relative angular positioning so that a clamp surface of the jaw member engages a shoulder of the second jaw member in a cocked position. When a torque is applied to the ring, the clamp members snap together to clamp over a hot line disposed between the clamp surfaces.
US08651890B2	Electrical connector having spring clip assist contact An electric connector is described which provides direct contact between an electric conductor and a respective counterpart. The connection is locked in place by means of one or more spring clips, for example associated with a casing. In a variant a single common casing is provided for the direct connection between a plurality of electric conductors and respective counterparts, which may be contact elements which are also associated with respective electric conductors or bump contacts of a PCB. In a further variant the counterpart is also an electric conductor, in such a way that direct contact is produced between two electric conductors held in mutual engagement by one or more spring clips.
US08651889B2	Connector The connector includes an electrically insulating one-part or multi-part housing, in which at least one contact element is arranged, which is accessible via a first opening of the housing by a contact element of a complimentary second connector, and which is connectable with an electrical cable that can be introduced through a second opening of the housing. The housing of the assembled connector, which is made from a first material, includes at least a first coupling element, which corresponds to at least one second coupling element that is included on a tubular element, which is manufactured from a second material which after processing includes a higher mechanical strength than the first material, and wherein the housing is releasably held within the tubular element by the releasably interlinked coupling elements.
US08651888B2	Electrical connector An electrical connector including a housing provided thereon with an opening through which a flat circuit device is inserted into the housing, a plurality of conductive contacts arranged on the housing, and a holding member formed in a body on the housing to be operative to hold the flat circuit device inserted in the housing and then to release the flat circuit device from holding by the holding member, wherein the holding member has a movable arm portion extending from an inside surface portion of the housing, and the movable arm portion is provided thereon with an engaging portion operative to engage with the flat circuit device inserted in the housing for holding the same and a releasing portion protruding from the movable arm portion through an aperture provided on the housing toward the outside of the housing and is operative to move the movable arm portion for disengaging the engaging portion from the flat circuit device.
US08651884B1	Ejectable memory card tray in a universal serial bus (USB) connector According to one general aspect, an apparatus includes a connector receptacle coupled to an electronic device. The connector receptacle is configured to receive a universal serial bus (USB) connector and a Micro SIM card. A connection member is disposed within the connector receptacle and configured to provide electrical communication between the Micro SIM card and the electronic device when the Micro SIM card is coupled to the connector receptacle. In some implementations, the electrical connector can also provide electrical communication between a USB connector and the electronic device when the USB connector is coupled thereto.
US08651881B2	Resonance modifying connector A connector assembly is provided that is suitable for modifying the resonant frequency of ground terminals used in conjunction with high data rate signal terminals. Ground terminals may be interconnected with a conductive bridge so as to provide ground terminals with a predetermined maximum effective electrical length. Reducing the effective electrical length of the ground terminal can move the resonance frequencies of the connector outside the operational range of frequencies at which signals will be transmitted.
US08651879B2	Compact power adapter A compact power adapter is disclosed. In one embodiment, a compact power adapter is facilitated by improved approaches to construct and assemble the power adapter. According to one aspect, connectors can serve to electrically couple blades (or prongs) of a power adapter plug to a printed circuit board assembly internal to a housing for the power adapter. The connectors serve to couple AC power to the printed circuit board assembly where the AC power can be converted to DC power. The connectors also facilitate assembly of the power adapter in that reliable interconnections can be provided without wires, soldering or other custom assembly operations. In one embodiment, a base for a power adapter plug of a power adapter can include a metal base connected to a blade (or prong) of the power adapter plug. The metal base can provide mechanical support to the blade as well as electrical connectivity to an internal terminal for the power adapter plug. The internal terminals used by a power adapter plug of a power adapter can be coupled to a printed circuit board assembly using connectors, thereby facilitating interconnection with electrical components used by the power adapter.
US08651876B2	Connector systems with magnetic retaining means Connector systems (10, 100) for electrically connecting two or more electrical components include a connector (14, 114) having one or more magnets (36a, 136a). Each magnet (36a, 136a) is attracted to another magnet (36b, 136b), or to a magnetically-attractable element on the other connector (14, 114) of the system (10, 100) when the connectors (14, 12, 112, 114) are mated. The magnetic attraction helps to maintain the connectors (14, 12, 112, 114) in a mated condition. The magnets (36a, 36b, 136a, 136b) can be oriented so that surface normals of pole faces (37a, 37b, 137a, 137b) of the magnets (36a, 36b, 136a, 136b) are angled in relation to a mating direction of the connectors (14, 12, 112, 114).
US08651875B2	Electromechanical pawl for controlling vehicle charge inlet access A charge connector latching mechanism integrated into a vehicle's charge inlet is provided, where the latching mechanism includes a retractable latching pawl. The retractable pawl is configured to be positioned in at least a first, default position where the pawl extends through an inlet surface of the charge inlet, and a second position where the pawl is retracted and does not extend through the inlet surface. In the first position the retractable pawl prevents insertion of a charge connector into the charge inlet if the charge connector is uncoupled from the inlet, and prevents removal of the charge connector if the charge connector is coupled to the inlet. In the second position the retractable pawl allows insertion/withdrawal of the charge connector into/from the charge inlet. The front surface of the retractable pawl may include a nub configured to fit within a recess within the front face of the charge connector.
US08651874B2	Transmission line with rotatable connector A transmission line with rotatable connector includes an insulated body, a connector a transmission line and a rotatable assembly kit. The insulated body includes a storage space. One end of the insulated body includes an opening slot and the other end of the insulating body includes a sliding slot. The connector is inside of the storage space. One end of the connector protrudes from the opening slot. One end of the transmission line is embedded in the storage space and electronically connected with the connector. The other end of the transmission line protrudes from the insulated body. The rotatable assembly kit includes a rotatable cylinder and a wire cover extending from one side of the rotatable cylinder. The rotatable cylinder is rotatably and pivotally connected to the rear of the connector. The partial transmission line protruding from the insulated body is covered by the wire cover and the partial transmission line horizontally moves along the sliding slot accompany with the rotation of the rotatable cylinder. The transmission line can properly change the direction of the connector to make it convenient for use and also can avoid the breakup of the junction of the transmission line at the bending point.

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