最新美国发明专利第2013-08-20期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

Document	Document Title
US08513543B1	Water-proofing cable connector A cable connector has a hollow housing, an input cap, an output cap, a wire separating base, a cable sealing assembly and a wire sealing assembly. The hollow housing has an input end and an output end. The input cap is mounted on the input end of the housing. The output cap is mounted on the output end of the housing so as to define a sealed space between the housing, the input cap and the output cap to hold the wire separating base, the cable sealing assembly and the wire sealing assembly inside. The wire separating base is mounted in the housing and has a first end and a second end. The cable sealing assembly is connected to the first end of the wire separating base. The wire sealing assembly is connected to the second end of the wire separating base.
US08513542B2	Integrated circuit leaded stacked package system An integrated circuit leaded stacked package system includes forming a no-lead integrated circuit package having a mold cap, and attaching a mold cap of an extended-lead integrated circuit package facing the mold cap of the no-lead integrated circuit package.
US08513539B2	Wiring board and method of manufacturing the same A wiring board has a base substrate, a conductive pattern formed on the base substrate, an insulation layer formed on the conductive pattern and the base substrate and including a resin-impregnated inorganic cloth, a conductive pattern formed on the insulating layer, a via formed in the insulation layer and connecting the conductive pattern formed on the base substrate and the conductive pattern formed on the insulating layer, and a through-hole connected to the conductive pattern formed on the base substrate, penetrating through the base substrate and having a hole diameter in a range of 10 μm to 150 μm.
US08513538B2	Television apparatus, electronic device, and circuit board structure According to one embodiment, a television apparatus includes a circuit board, a pad, a heat-transfer layer, and a block. The circuit board is mounted with an electronic component. The pad is provided on a surface of the circuit board. The heat-transfer layer is formed on the inner surface of a through hole in the circuit board. The through hole has an opening on the pad. The block contains a resin material and is located inside the heat-transfer layer to block the through hole.
US08513535B2	Circuit board and structure using the same A circuit board includes an insulating layer and a conductive layer formed on the insulating layer. The insulating layer contains a resin with high heat resistance. The conductive layer includes a metal carbide layer bonded to the insulating layer and containing a carbide of a first metal in group IV, V, or VI of the periodic table, and a first metal layer bonded to the metal carbide layer and containing the first metal.
US08513530B2	Package carrier and manufacturing method thereof A manufacturing method of a package carrier is provided. A substrate having a first surface, a second surface, and an opening communicating the first and second surfaces opposite to each other is provided. A first adhesive layer is formed on the first surface of the substrate. The first adhesive layer and the substrate define a notch. A thermal-conductive element is configured in the notch and fixed into the notch via the first adhesive layer. A second adhesive layer and a metal layer located on the second adhesive layer are formed on the second surface of the substrate. The metal layer is connected to a bottom surface of the thermal-conductive element. The thermal-conductive element is located between the metal layer and the first adhesive layer. The first adhesive layer is removed to expose the first surface of the substrate.
US08513526B2	Wiring harness A wiring harness 1 includes: an electric wire 2; and a connector 3. The electric wire 2 includes: a conductive core wire 21; and an insulating cover 22 for covering the core wire 21. The connector 3 is attached to an end 2a of the electric wire 2, and receives the end 2a of the electric wire 2. A first marker 6 and a second marker 7 are formed on an outer surface 22a of the cover 22 of the electric wire 2. The first marker 6 is formed by coloring a part of the outer surface 22a of the cover 22 of the electric wire 2 received in the connector 3 in a color A. The second marker 7 is formed by coloring a part of the outer surface 22a of the cover 22 of the electric wire 2 exposed to an outside of the connector 3.
US08513525B2	Strippable semiconductive composition comprising low melt temperature polyolefin The present invention relates to a semiconductive polymer composition having easily controllable stripping characteristics, especially for an electric power cable. The semiconductive polymer composition has an ethylene copolymer having polar co-monomer units, wherein the amount of the polar co-monomer units in the ethylene copolymer is 10 wt. % or more, based on the total weight of the ethylene copolymer; an olefin copolymer having propylene monomer units and monomer units of an alpha-olefin having at least 4 carbon atoms, wherein the olefin copolymer has a melting point of 110 ° C. or less, and carbon black in an amount of from 10 to 50 wt. %, based on the total weight of the semiconductive polymer composition, wherein the olefin copolymer (B) is prepared by using a metallocene polymerization catalyst.
US08513523B2	Relay terminal member, circuit structure including the same, and electronic unit A terminal relay member includes a plurality of relay terminals, each of which has a body section in which an opening is formed so as to penetrate the body section, and a terminal section to be connected to the circuit board; and a covering section for covering the body sections. The covering section includes holes corresponding to the openings. The opening is configured so that, by inserting a terminal pin of a connector to the opening, a part of the body section around the opening is deformed toward an inner wall of the hole of the covering section to contact the terminal pin.
US08513521B2	Electronic device enclosure having a cable holding device An electronic device enclosure includes a main enclosure, a cable holding device received in the main enclosure, and a cable which held by the cable holding device in different orientations. A first positioning slot and a second positioning slot are defined in the cable holding device. The cable is guided out of the cable holding device in one or more predetermined directions.
US08513519B2	Use of exfoliated clay nanoplatelets and method for encapsulating cations This invention relates to a method for making an electrolyte composition of a dye-sensitized solar cell comprising utilizing exfoliated clay nanoplatelets and the method for rapidly encapsulating cations. The electrolyte composition mainly includes exfoliated clay nanoplatelets, an ionic liquid and iodine. The method for rapidly encapsulating cation comprises adding the exfoliated clay nanoplatelets into a cationic solution, wherein the exfoliated clay nanoplatelets encapsulates cations and recovers into a layered structure such that phase separation of the solution occurs; and filtrating the solution to separate the clay nanoplatelets encapsulating the cations. The exfoliated clay nanoplatelets have a unique property of encapsulation for the cations, is suitable for use in an electrolyte composition for dye-sensitized solar cells, cationic drug encapsulation and environmental protection.
US08513515B1	Generating alternating current from concentrated sunlight An alternating current (AC, or ac) solar electric power generation system includes a primary concentrator to concentrate sunlight, one optional reflector to redirect the concentrated sunlight, a concentrating solar PV (CPV) module, a rotary electric connector, and a motor with an optional gearbox to spin the CPV module. The photovoltaic cells produce a varying electric output that is transmitted to the stationary contact by the rotary connector. Two groups of solar cells installed in the opposite direction with a phase difference of 180 degrees generate the one-phase AC electric power. An air and water mist, or other coolant system may cool the solar cells.
US08513512B2	Personalized music remixing A personal music mixing system with an embodiment providing beats and vocals configured using a web browser and musical compositions generated from said beats and vocals. Said embodiment provides a plurality of beats and vocals that a user may suitably mix to create a new musical composition and make such composition available for future playback by the user or by others. In some embodiments, the user advantageously may hear a sample musical composition having beats and vocals with particular user-configured parameter settings and may adjust said settings until the user deems the musical composition complete.
US08513510B1	Marching drum assembly A marching drum assembly of the present invention includes a supporter, at least an engaging element, at least a drum body, and a carrier. The engaging element includes a first and a second clipper boards which are parallel to each other, and a clipper trough is formed therebetween to receive a board-shape frame of the supporter. The engaging element also has a positioning element which is able to pivot relatively to the second clipper board. The positioning element is able to be fixed to the first clipper board after being pivoted toward the first clipper board. Thus, the two clipper boards are clamped tightly. Besides, one of the clipper boards connects with the drum body, and the carrier is capable of bearing the supporter. Thereby, the drum can be positioned at any preferred position on the frame, and easy adjustment and fixation can be achieved.
US08513507B2	Plants and seeds of common wheat cultivar WB-700 A wheat cultivar, designated WB-700, is disclosed. The invention relates to the seeds, plants, and hybrids of wheat cultivar WB-700, and to methods for producing a wheat plant produced by crossing plants from wheat cultivar WB-700 with themselves or with plants from another wheat variety. The invention also relates to methods for producing a wheat plant containing in its genetic material one or more transgenes and to the transgenic wheat plants and plant parts produced by those methods. The invention also relates to wheat varieties or breeding varieties and plant parts derived from wheat cultivar WB-700, to methods for producing other wheat varieties, lines or plant parts derived from wheat cultivar WB-700, and to the wheat plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid wheat seeds and plants produced by crossing wheat cultivar WB-700 with another wheat cultivar.
US08513505B2	Plants and seeds of common wheat cultivar WB-196 A wheat cultivar, designated WB-196, is disclosed. The invention relates to the seeds, plants, and hybrids of wheat cultivar WB-196, and to methods for producing a wheat plant produced by crossing plants from wheat cultivar WB-196 with themselves or with plants from another wheat variety. The invention also relates to methods for producing a wheat plant containing in its genetic material one or more transgenes and to the transgenic wheat plants and plant parts produced by those methods. The invention also relates to wheat varieties or breeding varieties and plant parts derived from wheat cultivar WB-196, to methods for producing other wheat varieties, lines or plant parts derived from wheat cultivar WB-196, and to the wheat plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid wheat seeds and plants produced by crossing wheat cultivar WB-196 with another wheat cultivar.
US08513502B2	Wheat variety W000350I1 A wheat variety designated W000350I1, the plants and seeds of wheat variety W000350I1, methods for producing a wheat plant produced by crossing the variety W000350I1 with another wheat plant, and hybrid wheat seeds and plants produced by crossing the variety W000350I1 with another wheat line or plant, and the creation of variants by mutagenesis or transformation of variety W000350I1. This invention also relates to methods for producing other wheat varieties or breeding lines derived from wheat variety W000350I1 and to wheat varieties or breeding lines produced by those methods.
US08513501B1	Maize variety inbred PH13HC A novel maize variety designated PH13HC and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH13HC with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH13HC through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH13HC or a locus conversion of PH13HC with another maize variety.
US08513500B1	Maize variety hybrid 10146900 A novel maize variety designated 10146900 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing maize variety 10146900 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into 10146900 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety 10146900, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety 10146900. This invention further relates to methods for producing maize varieties derived from maize variety 10146900.
US08513493B2	Hemipteran and coleopteran active toxin proteins from Bacillus thuringiensis A novel Bacillus thuringiensis crystal protein exhibiting insect inhibitory activity is disclosed. Growth of Lygus insects is significantly inhibited by providing the novel crystal protein in Lygus insect diet. Polynucleotides encoding the crystal protein, transgenic plants and microorganisms that contain the polynucleotides, isolated peptides derived from the crystal protein, and antibodies directed against the crystal protein are also provided. Methods of using the crystal protein and polynucleotides encoding the crystal protein to control Hemipteran insects are also disclosed.
US08513491B2	Dehydrin genes and promoters from coffee Dehydrin- and late embryogenic abundant (LEA) protein-encoding polynucleotides from coffee plants are disclosed. Also disclosed are a promoter sequence from a coffee dehydrin gene, and methods for using these polynucleotides and promoter sequences for gene regulation and manipulation of flavor, aroma, stress tolerance and other features of coffee beans.
US08513486B2	Cell nuclear transfer The present invention discloses methods for cell nuclear transfer that comprise for example modification of zona pellucida of an oocyte, and/or sectioning of oocytes into several parts. The present invention also discloses methods for producing a genetically modified non-human mammal. Genetically modified non-human mammals obtainable by the disclosed methods are also within the scope of the present invention. Disclosed are also methods for cryopreservation of cells.
US08513485B2	Non human transgenic mammal comprising a transgene comprising a nucleotide sequence encoding a ribosomal protein fused to a peptide tag The invention provides methods for isolating cell-type specific mRNAs by selectively isolating ribosomes or proteins that bind mRNA in a cell type specific manner, and, thereby, the mRNA hound to the ribosomes or proteins that bind mRNA. Ribosomes, which are riboprotein complexes, bind mRNA that is being actively translated in cells. According to the methods of the invention, cells are engineered to express a molecularly tagged ribosomal protein or protein that binds mRNA by introducing into the cell a nucleic acid comprising a nucleotide sequence encoding a ribosomal protein or protein that binds mRNA fused to a nucleotide sequence encoding a peptide tag. The tagged ribosome or mRNA binding protein can then be isolated, along with the mRNA bound to the tagged ribosome or mRNA binding protein, and the mRNA isolated and further used for gene expression analysis. The methods of the invention facilitate the analysis and quantification of gene expression in the selected cell type present within a heterogeneous cell mixture, without the need to isolate the cells of that cell type as a preliminary step.
US08513483B2	Hydrophobic surface coated material for use in absorbent articles An improved barrier member for an absorbent article that includes a nonwoven treated with a hydrophobic surface coating. The hydrophobic surface coating includes a non-aqueous, solventless, multicomponent silicone composition. The hydrophobic surface coating may be substantially free of aminosilicones.
US08513476B2	Process for producing light olefins from a feed containing triglycerides The process combines hydroconversion and catalytic cracking starting from a feed containing triglycerides, at concentrations of fatty acids above 85%, which maximizes the yields of light olefins, chiefly ethylene and propylene, while reducing the yield of gasoline, with conversion greater than 80 wt. %.
US08513475B2	Method for making hydrocarbons by using a lipid derived from a biological organism and hydrotalcite The present invention relates to a method in which a catalytic reaction is used in order to produce hydrocarbons from renewable starting material derived from biological organisms such as vegetable lipids, animal lipids, and lipids extracted from macroalgae and microalgae, and more specifically relates to a method for selectively making a hydrocarbon, which is suitable for making gasoline or diesel, by removing the oxygen contained in the starting material without consuming hydrogen. In the present invention, the production takes place by bringing the starting material into contact with hydrotalcite, which constitutes a catalyst, thereby removing oxygen via a decarboxylation or decarbonylation reaction; and the starting material is one or more such material selected from triglycerides, fatty acids, and fatty acid derivatives obtained from a renewable source of supply originating from a biological organism.
US08513474B2	Process for the manufacture of fluorinated olefins Provided are methods for producing fluorinated organic compounds, which preferably comprises converting at least one compound of formula (I) CH2XCHZCF3 to at least one compound of formula (II) CHX═CZCF3 where X and Z are independently H or F, with the proviso that X and Z are not the same. The converting step comprises catalytically reacting at least one compound of formula (I), preferably via dehydrogenation or oxidative dehydrogenation. In another aspect, the inventive method of preparing fluorinated organic compounds comprises converting a reaction stream comprising at least one pentafluoropropene to a product stream comprising at least one pentafluoropropane and at least one compound of formula (I), separating out the compound of formula (I) from the product stream, and converting the compound of formula (I) separated from the product stream to at least one compound of formula (II), wherein the conversion the compound of formula (I) to 3,3,3-trifluoropropyne is substantially limited.
US08513470B2	Process for oxidation on fixed catalytic bed of methanol to formaldehyde A process for the fixed bed oxidation of methanol to formaldehyde wherein the bed comprises at least two layers having different catalytic activity, wherein the layer of lower activity is comprised in the part of the bed from which the reactant gas mixture enters and its activity is calibrated so that the maximum hot spot temperature in the layer is comprised between 350° C. and 430° C. and is higher than the maximum hot spot temperature of the layer of greater activity formed by pure catalyst, and wherein during the period in which the situation of the maximum hot spot temperature of the layer of lower activity remains at the values cited above, the conversion of methanol is higher than 96% by mols.
US08513469B2	Hydroformylation process with doubly open-ended bisphosphite ligand A continuous hydroformylation process for producing at least one aldehyde product by utilizing a transition metal and a ligand mixture comprising an organopolyphosphite and an organomonophosphine, with improved stability of the organopolyphosphite ligand. The process involves reacting one or more olefinically-unsaturated compounds with carbon monoxide and hydrogen in the presence of an organopolyphosphite ligand and an organomonophosphine ligand, at least one of such ligands being bonded to a transition metal to form a transition metal-ligand complex hydroformylation catalyst. Surprisingly the addition of the organomonophosphine to a Rh/organopolyphosphite catalyst system did not result in a significant loss of reaction rate.
US08513467B2	Production of 2,4-diones from 4-hydroxy-6-substituted-2-pyrones Described is a method of making 2,4-diones via acid catalyzed or thermally induced ring-opening of a 4-hydroxy-6-substituted-2-pyrone to yield a 2,4-dione.
US08513466B2	Class of soluble, photooxidatively resistant acene derivatives The present invention is directed towards a new class of semi-conducting acene derivatives. These compounds are all soluble species and they all possess superior resistance to photooxidation as compared to their counterparts that lack the substitution patterns disclosed herein.
US08513465B2	Potassium organotrifluoroborate derivative and a production method therefor Provided are a production method for a potassium organotrifluoroborate compound having a hydroxyl group, and a novel potassium organotrifluoroborate compound having a hydroxyl group. The production method is advantageous in that a potassium organotrifluoroborate compound can be produced in a single reaction without recourse to a process of isolating and purifying an intermediate. The novel potassium organotrifluoroborate compound having a hydroxyl group is useful as a reactant which is widely used in the total synthesis of physiologically active natural products and diverse organic synthesis reactions including halogen substitution reactions, 1,2- and 1,4-addition reactions using a rhodium (Rh) catalyst, and Suzuki coupling reactions using a palladium (Pd) catalyst.
US08513463B2	Process for the production of nitrogen or phosphorus containing compounds from synthesis gas A process is described for the production of one or more of linear nitriles, amides and formamides which includes reacting a nitrogen containing compound, such as ammonia or NOx, and a synthesis gas over a catalyst at a temperature of between 160° C. and 400° C. and a pressure of between 1 bar and 50 bar. A further process for the production of one or more of linear phosphorous containing compounds is also described, which includes reacting a phosphorous containing compound, such as a phosphine, and a synthesis gas over a catalyst at a temperature of between 160° C. and 400° C. and a pressure of between 1 bar and 50 bar. A supported cobalt, iron, ruthenium or rhodium catalyst or an unsupported (bulk) promoted iron catalyst, modified with a promoter is used. The synthesis gas is a mixture of hydrogen and carbon monoxide, in a ratio from 0.5:1 to 5:1; or a mixture of hydrogen and carbon dioxide; or a mixture of water and carbon monoxide. The suppression of the formation of oxygenates in the process is a feature of the invention and oxygenates may even be included in the feed to become converted to corresponding nitrogen containing compounds in the process.
US08513459B2	Process for producing perfluoropolyether carboxylic acid fluoride Perfluoropolyether carboxylic acid fluoride having the following general formula: F(CF2CF2CF2O)nCF2CF2COF (n: 2-200, preferably 35-70) can be produced by starting fluorination reaction of polyfluoropolyether carboxylic acid having the general formula as a tetrafluorooxetane polymer: F(CH2CF2CF2O)nCH2CF2COF (n: 2-200) in a dispersed state in a perfluoropolyether-based solvent with a fluorine gas at 50°-80° C., then slowly elevating the fluorination reaction temperature, and finally completing the fluorination reaction at 100°-120° C., where even in the case of fluorination reaction of the starting material with a high degree of polymerization the desired product can be produced in high yield, while suppressing the decomposition and keeping the high degree of polymerization substantially.
US08513456B2	Method for producing a carnosic acid-rich plant extract A carnosic acid-rich plant extract can be produced by extracting a dried and comminuted plant material containing carnosic acid with supercritical CO2 at a pressure of at least 200 bar and at a temperature of at most 100° C. In a first step, supercritical CO2 in a quantity of 10 to 50 kg of CO2 per kg of plant material is passed through the plant material to obtain a first CO2 extract. In a second step, additional supercritical CO2 is passed through the plant material to obtain a second CO2 extract, and a carnosic acid-rich plant extract is separated from the second CO2 extract by lowering the pressure.
US08513454B2	Preparation of (phosphonyl) aromatic diesters and acids The composition of a (phosphonyl) aromatic compound represented by is provided. In this composition, R1(a) and R1(b) are each independently H, CnH2n+1, phenyl or benzyl; R2(a) and R2(b) are each independently H, CnH2n+1, phenyl or benzyl with the proviso that no more than one R2(a) and no more than one R2(b) can be phenyl or benzyl; R3(a) and R3(b) are each independently CnH2n+1, phenyl or benzyl; and, n is an integer of 1-10; and p is an integer of 1-10. The disclosed composition can find utility in improving flame retardancy of polyesters, aramids and nylons.
US08513452B1	Brønsted acid-catalyzed asymmetric allylation and propargylation of aldehydes A method synthesizing homoallylic or homopropargylic alcohols was developed to react aldehydes with allyl boronates, such as allylboronic acid pinacol ester, or allenylborates in the presence of a catalytic amount of a chiral binaphthyl-derived chiral phosphoric acid. The method showed enhanced enantiocontrol and chemical yield, which increased with lower temperatures. A large series of aldehydes were tested under these catalytic conditions and wide successful substrate scope was found, including aryl, heteroaryl, aromatic aldehydes, heteroaryl aldehydes, α,β-unsaturated aldehydes and aliphatic aldehydes, and alkyl aldehydes. Likewise, the use of crotyl boronates (E and Z) were successfully reacted with aryl aldehydes under the conditions to allow for highly enantio- and diasteo-selective crotylation.
US08513448B2	Cyclic siloxane compound, a material for forming Si-containing film, and its use The present invention has the objects to provide a novel material for forming Si-containing film, especially a material containing a cyclic siloxane compound suitable to a PECVD equipment for low dielectric constant insulating film, and to provide an Si-containing film using the same, and a semiconductor device containing those films. The present invention relates to a material for forming Si-containing film, containing a cyclic siloxane compound represented by the following general formula (1) (In the formula, A represents a group containing at least one selected from the group consisting of an oxygen atom, a boron atom and a nitrogen atom, n is 1 or 2, and x is an integer of from 2 to 10.), and its use.
US08513441B2	Prostaglandin synthesis and intermediates for use therein Fused cyclopentane-4-substituted 3,5-dioxalane lactone compounds useful as an intermediate in the synthesis of prostaglandin analogs are provided. The compounds have the formula A: wherein R represents an aryl group such as p-methoxyphenyl. This compound can be reacted with a lower alkyl aluminum compound to open the dioxalane ring and reduce the lactone to lactol, without over-reducing to diol. The resulting compound can be functionalized to insert chemical side groups of target prostaglandins, adding the required α-side chain and then the required ω-side chain sequentially and independently of each other. The compounds and process are particularly suitable for preparing lubiprostone.
US08513438B2	Process for the preparation of (6S)-(-)-5,6,7,8-tetrahydro-6-[propyl-(2-thienyl)ethyl]amino-1-naphthol (Rotigotine) The present invention describes a novel process for the preparation of (6S)-(−)-5,6,7,8-tetrahydro-6-[propyl-(2-thienyl)ethyl]amino-1-naphthol (Rotigotine) comprising: (a) acetylating (S)-(−)-5-hydroxy-N-n-propyl-2-aminotetraline to afford the acetate; (b) reacting this acetate, (−)-5-acetoxy-N-n-propyl-2-aminotetraline, with 2-(2-thienyl)ethanol 2-nitrobenzenesulfonate; (d) hydrolyzing (6S)-(−)-1-acetoxy-5,6,7,8-tetrahydro-6-[propyl-(2-thienyl)ethyl]amino-1-naphthalene to afford (6S)-(−)-5,6,7,8-tetrahydro-6-[propyl-(2-thienyl)ethyl]amino-1-naphthol (Rotigotine) and (d) purifying rotigotine either by the acetylation reaction and subsequent hydrolysis of the formed acetate or by salification of rotigotine through hydrochloride or hydrobromide formation and subsequent base release. Rotigotine is a dopamine agonist and is indicated for the treatment of Parkinson's disease.
US08513437B2	Pyrrolidino-1,4-naphthoquinone deriviatives and their use for treating malignancies and cardiovascular diseases The invention provides pyrrolidino-substituted 1,4-naphthoquinone derivatives that modulate the activity of protein kinases, and it relates to the use of the derivatives in pharmaceutical compositions for treating cardiovascular disorders and malignancies. The invention particularly provides medicaments for treating disorders associated with MAPKs signaling, ERKs signaling, p38 signaling, and JNKs signaling.
US08513436B2	Pyrazolyl and pyrimidinyl tricyclic enones as antioxidant inflammation modulators Disclosed herein are novel antioxidant inflammation modulators, including those of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds. Methods and intermediates useful for making the compounds, and methods of using the compounds and compositions thereof are also provided.
US08513435B2	Method for preparing aminoethyl imidazolidinone or the thiocarbonyl thereof The present invention relates to a method for preparing 1-(2-aminoethyl)imidazolidin-2-one or the thiocarbonyl thereof, and also to the product that can be obtained according to this method, and which has a purity of at least 98%, and to the uses thereof.
US08513433B2	Small molecule inhibitors of PARP activity Compounds and pharmaceutical compositions are provided that inhibit the activity of poly ADP-ribose synthetase (PARP). Such compounds are useful in the treatment of various diseases, conditions and injuries such as stroke, myocardial infarction, ischemia-perfusion injury in various organs, traumatic brain injury, atherosclerosis, inflammatory diseases and cancer.
US08513429B2	Synthesis of epothilones, intermediates thereto and analogues thereof The present invention provides compounds of formula (I): as described generally and in classes and subclasses herein. The present invention additionally provides pharmaceutical compositions comprising compounds of formula (I) and provides methods of treating cancer comprising administering a compound of formula (I).
US08513428B2	Process for preparing atazanavir bisulfate and novel forms A process is provided for preparing the HIV protease inhibitor atazanavir bisulfate wherein a solution of atazanavir free base is reacted with concentrated sulfuric acid in an amount to react with less than about 15% by weight of the free base, seeds of Form A crystals of atazanavir bisulfate are added to the reaction mixture, and as crystals of the bisulfate form, additional concentrated sulfuric acid is added in multiple stages at increasing rates according to a cubic equation, to effect formation of Form A crystals of atazanavir bisulfate.A process is also provided for preparing atazanavir bisulfate as Pattern C material. A novel form of atazanavir bisulfate is also provided which is Form E3 which is a highly crystalline triethanolate solvate of the bisulfate salt from ethanol.
US08513423B2	Piperidin-4-yl-azetidine diamides as monoacylglycerol lipase inhibitors Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds, and enantiomers, diastereomers, and pharmaceutically acceptable salts thereof, are represented by Formula (I) as follows: wherein Y, Z, and R are defined herein.
US08513422B2	Piperidine derivative As a result of studies on compounds having a selective inhibitory activity against 17βHSD type 5, the present inventors have confirmed that a {1-[(indol-2-yl)carbonyl]piperidyl}alkanol derivative has a potent selective inhibitory activity against 17βHSD type 5. The invention has been completed based on these findings. The compound of the present invention can be used as an agent for treating and/or an agent for preventing diseases associated with 17βHSD type 5, such as benign prostatic hyperplasia and prostate cancer, without accompanying adverse effects due to a decrease in testosterone.
US08513421B2	Substituted hydroxamic acids and uses thereof This invention provides compounds of formula (I): wherein R1a, R1, R2a, and R2b have values as described in the specification, useful as inhibitors of HDAC6. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of proliferative, inflammatory, infectious, neurological or cardiovascular diseases or disorders.
US08513420B2	Amino-naphthyridine derivatives The present invention relates to new compounds having an amino-naphthyridine group. In particular, the present invention relates to new compounds, its stereoisomers and pharmaceutically acceptable salts or solvates thereof having a first unit (moiety) selected from the group of a phenyl derivative, a biphenyl derivative or a diphenyl alkane derivative and at least one amino-naphthyridine group linked with the first unit via a linking group. In specific embodiments, the present invention relates to compounds having a phenyl derivative unit and three amino-naphthyridine groups bound to the phenyl derivative unit via a linking group as well as salts or solvates thereof, in particular, pharmaceutically acceptable salts or solvates thereof. Further, the present invention relates to pharmaceutical compositions comprising said compounds. The compounds are particularly useful for treating or preventing infections, like viral infections.
US08513416B2	Bisamide-zinc bases The present invention relates to zinc amide bases of the general formula (I) (R1R2N)2—Zn.aMgX12.bLiX2 (I) wherein R1 and R2 are each independently selected from substituted or unsubstituted, linear or branched alkyl, alkenyl, alkynyl or silyl derivatives thereof, and substituted or unsubstituted aryl or heteroaryl, and wherein R1 and R2 can form together a ring structure, or R1 and/or R2 can be part of a polymer structure; X12 is a divalent anion or two monovalent anions that are independent from each other; X2 is a monovalent anion; a is >0; and b is >0. The zinc amide bases can be used, amongst other things, for deprotonation and metallization of aromatics.
US08513415B2	Preparation of C-pyrazine-methylamines A process for preparing a compound of formula (I) or a salt thereof: (I) wherein R1 is H or optionally substituted aryl or heteroaryl; comprising reacting 2,3-dichloropyrazine with a suitable diaryl imine followed by hydrolysis.
US08513413B2	Process for the preparation of nitroorotic acid Subject of the present invention is a new improved process for the preparation of nitroorotic acid via nitration of orotic acid.
US08513406B2	Pharmaceutical compositions comprising forms of 5-azacytidine The invention provides novel polymorphic and pseudopolymorphic crystalline forms of 5-azacytidine, along with methods for preparing said forms, wherein 5-azacytidine is represented by the formula: The invention also includes pharmaceutical compositions comprising said forms.
US08513403B2	Modified siRNA molecules and uses thereof The present invention provides chemically modified siRNA molecules and methods of using such siRNA molecules to silence target gene expression. Advantageously, the modified siRNA of the present invention is less immunostimulatory than its corresponding unmodified siRNA sequence and retains RNAi activity against the target sequence. The present invention also provides nucleic acid-lipid particles comprising a modified siRNA, a cationic lipid, and a non-cationic lipid, which can further comprise a conjugated lipid that inhibits aggregation of particles. The present invention further provides methods of silencing gene expression by administering a modified siRNA to a mammalian subject. Methods for identifying and/or modifying an siRNA having immunostimulatory properties are also provided.
US08513400B2	Modulation of HIF1α and HIF2α expression Compounds, compositions and methods are provided for modulating the expression of HIF1α and/or HIF2α. The compositions comprise oligonucleotides, targeted to nucleic acid encoding HIF1α and HIF2α. Methods of using these compounds for modulation of HIF1α and/or HIF2α expression and for diagnosis and treatment of disease associated with expression of HIF1α and/or HIF2α are provided.
US08513398B2	Human papilloma virus probes for the diagnosis of cancer In one embodiment, the invention relates to a method of detecting cervical cancer, and other types of cancer, using a combination of at least three genomic clones, or fragments thereof, of high risk Human Papilloma Virus. For example, the invention relates to a composition comprising at least three full length genomic clones, or fragments thereof, of high risk Human Papilloma Viruses.
US08513392B2	Conjugation of streptococcal capsular saccharides Three conjugation methods for use with the capsular saccharide of Streptococcus agalactiae. In the first method, reductive animation of oxidized sialic acid residue side chains is used, but the aldehyde groups are first aminated, and then the amine is coupled to a carrier via a linker. In the second method, sialic acid residues and/or N-acetyl-glucosamine residues are de-N-acetylated to give amine groups, and the amine groups are coupled to a carrier protein via a linker. In the third method, linkage is via galactose residues in the capsular saccharide rather than sialic acid residues, which can conveniently be achieved using galactose oxidase.
US08513391B2	Monoclonal antibodies for Ebola and Marburg viruses Described herein are a number of Ebola and Marburg monoclonal antibodies.
US08513387B2	Methods and compositions for detecting amyotrophic lateral sclerosis The invention provides binding proteins that bind to misfolded or monomeric SOD1, and not to native homodimeric SOD1. The invention also includes methods of diagnosing, detecting or monitoring amyotrophic lateral sclerosis in a subject. In addition, the invention provides methods of identifying substances for the treatment or prevention of amyotrophic lateral sclerosis and kits using the binding proteins of the invention.
US08513385B2	Selective extraction of glutelin proteins from freshwater or saltwater algae Methods for selective extraction and fractionation of algal proteins from an algal biomass or algal culture are disclosed. A method of selective removal of products from an algal biomass provides for single and multistep extraction processes which allow for efficient separation of algal proteins. These proteins can be used as renewable sources of proteins for animal feedstocks and human food. Further, lipids remaining in the algal biomass after extraction of proteins can be used to generate renewable fuels.
US08513383B2	Selective extraction of proteins from saltwater algae Methods for selective extraction and fractionation of algal proteins from an algal biomass or algal culture are disclosed. A method of selective removal of products from an algal biomass provides for single and multistep extraction processes which allow for efficient separation of algal proteins. These proteins can be used as renewable sources of proteins for animal feedstocks and human food. Further, lipids remaining in the algal biomass after extraction of proteins can be used to generate renewable fuels.
US08513379B2	Depolymerization method for polymer containing ester bond in main chain and method for producing polymer containing ester bond in main chain from depolymerization product The invention provides a depolymerization method for a polymer containing an ester bond in a main chain, by causing a solid acid catalyst to act on a polymer containing an ester bond in a main chain to depolymerize the polymer, thereby obtaining a re-polymerizable monomer and/or oligomer as a depolymerization product, and a method for producing a polymer containing an ester bond in a main chain, by polymerizing the re-polymerizable monomer and/or oligomer obtained by the depolymerization method.
US08513377B2	Selenium-based monomers and conjugated polymers, methods of making, and use thereof Substituted selenophene monomers, and polymers and copolymers having units derived from a substituted selenophene are disclosed. Also provided are methods of making and using the same.
US08513376B2	Polyamides and amidoamines from selectively modified amine amines The present disclosure provides polyamides and amidoamine curing agents including the reaction product of (1) a modified amine component comprising at least one multifunctional amine of structure 1: wherein R1 is selected from C1-C16 linear, cyclic, and branched alkyl, alkenyl, and alkaryl groups; R2 and R4 are hydrogen, R3 is R1 or hydrogen, X, Y, and Z are independently selected from C2-C10 alkylene, hexylene and cycloalkylene groups, n=0, 1, 2, 3, 4, 5, 6, or 7; and (2) a fatty acid component. Exemplary fatty acid components include at least one of monomer fatty acids, dimer fatty acids, trimer fatty acids, polymer fatty acids, esters of monomer, dimer, trimer, and polymer fatty acids and combinations thereof. The method for making the curing agents and articles formed therefrom are also disclosed.
US08513372B2	Asymmetric photo-patternable sol-gel precursors and their methods of preparation Described herein are photo-patternable sol-gel precursors and their methods of preparation. The sol-gel precursors are thermally stable and form compositions that have high refractive indices and low optical loss values. The precursors can be used to make sol-gel compositions that are ideally suited toward optical waveguide applications in the realm of telecommunications wavelengths.
US08513371B2	Amino alkoxy-modified silsesquioxanes and method of preparation An amino alkoxy-modified silsesquioxane (AMS) comprising one or more compounds selected from the group consisting of an amino AMS, an amino/mercaptan co-AMS, an amino/blocked mercaptan co-AMS, mixtures thereof, and a weak acid-neutralized solid or aqueous solution thereof, and a method of making the amino AMS, are presented. The compounds are useful in compounding, processing, cure and storage of silica-reinforced rubbers because they contain low levels of volatile organic compounds (VOC).
US08513369B2	Long chain-branched ethylene-alpha olefin copolymer The present invention relates to an ethylene-alpha olefin copolymer comprising long chain branches (LCB), while having a narrow molecular weight distribution. The ethylene-alpha olefin copolymer can be prepared by a continuous solution polymerization process using an activated catalyst composition containing a Group 4 transition metal compound having a monocyclopentadienyl ligand, to which a quinoline amino group is introduced.
US08513365B2	Polymerization process with improved polymer homogeneity The present invention relates to a process for the polymerization of an olefin monomer. In particular, the present invention relates to a process for the polymerization of an olefin monomer and one or more optional comonomers in presence of a polymerization catalyst and hydrogen, said process being characterized by an improved control of the hydrogen concentration in the polymerization reactor. In addition, the present invention provides for an improved hydrogen feeding system to a polymerization reactor. Furthermore, the present invention provides for a polymerization reactor comprising such an improved hydrogen feeding system.
US08513364B2	Production method of water-absorbent resin A production method of a water-absorbent resin includes the steps of: obtaining a hydrogel by supplying monomer liquid to a reaction device so that the monomer liquid is polymerized; and detaching the hydrogel from the reaction device, wherein the reaction device's surface in contact with the monomer liquid at a position where polymerization occurs is made of a fluororesin having a melt viscosity of less than 1×108 poise at 380° C. On this account, it is possible to obtain a water-absorbent resin having less amounts of an extractable content with high productivity and it is possible to carry out continuous production for an extended period of time.
US08513358B2	Composition of (Meth)acrylate resin and hydroxy group-containing aromatic resin The present invention relates to a transparent resin composition which comprises (a) a (meth)acrylate based resin comprising one or more (meth)acrylate based derivatives; and (b) an aromatic based resin having a chain having the hydroxy group containing portion and an aromatic moiety.
US08513356B1	Diblock copolymer blend composition A diblock copolymer blend containing a unique combination of an ordered poly(styrene)-b-poly(methyl methacrylate) diblock copolymer and a disordered poly(styrene)-b-poly(methyl methacrylate) diblock copolymer is provided. Also provided are substrates treated with the diblock copolymer blend.
US08513355B2	Graft copolymer improving adhesion resistance and impact strength, method of preparing the same, and PVC composition comprising the same Disclosed is a graft copolymer highly improving the adhesion resistance and impact strength, a method of preparing the same, and PVC composition containing the same, wherein the graft copolymer comprises i) 55 to 85 wt % of a conjugated diene-based rubber core; and ii) 15 to 45 wt % of a graft shell surrounding the rubber core, and formed by comprising a (meth)acrylate-based monomer, and at least one selected from the group consisting of a vinyl-based monomer having a polyalkylene oxide group represented by the following Formula 1; in which the graft copolymer includes 0.1 to 5 wt % of the vinyl-based monomer having the polyalkylene oxide group represented by the following Formula 1: wherein R is independently hydrogen, or C1 to C4 alkyl group, and n is independently 3 to 14.
US08513353B2	Forming copolymer from bicontinuous microemulsion comprising monomers of different hydrophilicity A copolymer defines interconnected pores and comprises polymerized monomers. The monomers comprise a first monomer more hydrophilic than 2-hydroxyethyl methacrylate (HEMA), and a second monomer as hydrophilic as, or less hydrophilic than, HEMA. In a method of forming a polymer, a bicontinuous microemulsion comprising water, a surfactant, and a combination of monomers copolymerizable for forming a porous copolymer is provided. The combination of monomers comprises the first and second monomers. The monomers in the bicontinuous microemulsion are polymerized to form the porous copolymer. The first monomer may comprise N-vinylpyrrolidone (NVP) or methacrylic acid (MAA). The second monomer may comprise HEMA or methyl methacrylate (MMA).
US08513350B2	Positive type photosensitive resin composition A positive type photosensitive resin composition for forming patterned resin film is provided. The patterned resin film has high transparency, low dielectric constant, high solvent resistance, high water resistance, high acid resistance, high alkali resistance, high heat resistance, and excellent adhesive properties with the substrate, which is obtained by developing with an alkali solution. The positive type photosensitive resin composition contains copolymer of compound of formula (I) and 1,2-quinonediazido compound, or further mixes with other alkali-soluble polymers, in formula (I), R1 is hydrogen or alkyl group having 1-5 carbon atoms in which any hydrogen may be replaced by fluorine; and R2, R3 and R4 are independently hydroxyl group, alkyl group having 1-5 carbon atoms, alkoxyl group having 1-5 carbon atoms or —O(Si(ClH2l+1)2O)mSi(CpH2p+1)3, 1 is an integer of 1-5, m is 0 or an integer of 1-10, n is an integer of 1-5, and p is an integer of 1-5.
US08513345B2	Exoergic filler composition, resin composition, exoergic grease and exoergic coating composition The present disclosure provides an exoergic filler composition which is able to exert superior exoergic property, and a resin composition, a grease, and a coating composition which having superior exoergic property, respectively, by using the above-mentioned exoergic filler composition. The exoergic filler composition contains 1 to 50 volume % of a needle-shaped zinc oxide having an average long diameter of 0.1 to 10 μm, an average short diameter of 0.025 to 2.5 μm, aspect ratio defined by (average long diameter)/(average short diameter) of 4 or more and specific surface area according to BET method of 50 m2/g or less, and 50 to 99 volume % of other exoergic filler.
US08513342B2	Durable superhydrophobic coatings Durable superhydrophobic coating composition having a composition ranging from about 10 to about 80 w.t. % of an acrylic polymer resin, from about 5 to about 40 w.t. % of a polysiloxane oil, from about 1 to about 50 w.t. % of hydrophobic particles, from about 0.1 to about 10 w.t. % metal oxides, and the remainder being one or more solvents and optionally other additives. Methods of making the coating, as well as coated substrates, are also provided.
US08513341B2	Polylactic acid resin composition and molded article thereof A polylactic acid resin composition containing 100 parts by weight of a polylactic acid compound (A) having a specific moiety represented by the formula (1): —X1—R1—X2— and having a weight average molecular weight (Mw) of 5,000 to 500,000, 5 to 2,000 parts by weight of a lactic acid resin (B) and 0.1 to 10 parts by weight of at least one kind of a transparent nucleating agent (C) selected from carboxylic acid amides, aliphatic alcohols and aliphatic carboxylic acid esters. In the formula (1), X1, X2 and R1 are defined. The resin composition can exhibit improved heat resistance (high crystallinity) and transparency without impairing the rigidity of the polylactic acid resin. A molded article composed of the resin composition is also provided.
US08513340B2	Method of reducing chatter A method for reducing chatter in an extrusion process, which includes the steps of preparing an extrusion composition by combining a polymer composition with a chatter-reducing formulation, and extruding the extrusion composition to provide a substantially continuous extrudate. The chatter-reducing formulation comprises an alkyltin mercaptide and dibutyltin dilaurate. The resultant extrudate exhibits reduced chatter, which is categorized according to the Reed Scale as less than or equal to 2.
US08513332B2	Ink composition for color filter, method for preparing a color filter using the same, and color filter Disclosed is a color filter ink composition that includes an acrylic-based copolymer resin including repeating units represented by a particular chemical formula, a polymerizable monomer, a pigment, and a solvent. According to the present invention, the color filter ink composition can have excellent ejection properties and ejection stability by using a new acrylic-based copolymer resin as a binder resin, and also can have excellent storage stability, so that it can be used for a long period. In addition, a pattern formed using the color filter ink composition can have improved heat resistance, chemical resistance, and film strength.
US08513327B2	Adhesive composition for dental use An adhesive composition for dental use exhibiting acidic property, including a mixture of a polymerizable monomer component (A) containing a phosphoric acid-type polymerizable monomer having an acidic group derived from phosphoric acid, and a multivalent metal ion-releasing component (B), wherein the multivalent metal ion-releasing component (B) is capable of releasing at least earth metal ions, and in the composition, earth metal ions stemming from the component (B) are present together with the phosphoric acid-type polymerizable monomer in such an amount that a total valency ratio (RE) defined by the following formula (1) is in a range of 0.2 to 3.0. The adhesive composition is capable of strongly adhering and fixing a composite resin or a prosthetic material to a tooth for extended periods of time maintaining stability. RE=TVE/TVA (1) wherein TVE is a total valency of the earth metal ions contained in said composition, and TVA is a total valency of the acidic groups of the phosphoric acid-type polymerizable monomer contained in said composition.
US08513326B2	Carbamate-methacrylate monomers and their use in dental applications The present invention relates, generally, to monomers containing carbamate-methacrylates or derivatives of carbamate-methacrylates, processes for making the monomers, and compositions comprising the monomers. The present invention also relates to methods of using the monomers, such as in dental applications, and in particular, dental restorative resins.
US08513324B2	Polymeric articles comprising oxygen permeability enhancing particles The present invention relates to a composition comprising a hydrogel polymer having less than 100% haze, and distributed therein an oxygen enhancing effective amount of oxygen permeable particles having an oxygen permeability of at least about 100 barrer, average particle size less than about 5000 nm.
US08513319B2	Mesoporous carbon materials The invention is directed to a method for fabricating a mesoporous carbon material, the method comprising subjecting a precursor composition to a curing step followed by a carbonization step, the precursor composition comprising: (i) a templating component comprised of a block copolymer, (ii) a phenolic compound or material, (iii) a crosslinkable aldehyde component, and (iv) at least 0.5 M concentration of a strong acid having a pKa of or less than −2, wherein said carbonization step comprises heating the precursor composition at a carbonizing temperature for sufficient time to convert the precursor composition to a mesoporous carbon material. The invention is also directed to a mesoporous carbon material having an improved thermal stability, preferably produced according to the above method.
US08513317B2	Process for producing expanded polyolefin resin particles and expanded polyolefin resin particles Provided is a process for producing expanded polyolefin resin particles whose cells are not made nonuniform or extremely smaller as seen in conventional expanded particles, whose cell diameter and expansion ratio can be easily controlled independently, and which, when subjected to in-mold expansion molding, give in-mold expanded molded products satisfactory in fusibility and excellent in surface properties. The process is a process for producing expanded polyolefin resin particles by: dispersing polyolefin resin particles together with an aqueous dispersion medium into a closed vessel; heating the polyolefin resin particles up to or above a softening temperature of the polyolefin resin particles; and releasing the polyolefin resin particles into a zone whose pressure is lower than an internal pressure of the closed vessel, with use as a foaming agent of water serving as the dispersion medium, the polyolefin resin particles being composed of a polyolefin resin composition including: polyolefin resin; a substance selected from among polyethylene glycol, polyvalent alcohol having a carbon number of not less than 3 to not more than 6, and a water-absorbing substance having no function of forming foaming nuclei; and a foam nucleating agent.
US08513312B2	Hydrocarbon synthesis process This invention relates to a Fischer Tropsch process using a catalyst activated in accordance with the invention. More particularly the invention relates to a three phase Low Temperature Fischer Tropsch process wherein CO and H2 are converted to hydrocarbons and possibly oxygenates thereof by contacting syngas including CO and H2 in the presence of an iron based Fischer Tropsch catalyst, wherein the ratio of H2:CO in the feed is between 2.5 and 1, and wherein the iron based Fischer Tropsch catalyst is activated according to the steps of: (a) providing an iron catalyst including iron in a positive oxidation state; and (b) contacting the iron catalyst in a reactor with a reducing gas selected from CO and a combination of H2 and CO; at a temperature of at least 245° C. and below 280° C.; at a reducing gas pressure of above 0.5 MPa and not more than 2.2 MPa; and at a GHSV of total gas fed to the reactor of at least 6000 ml(N)/g cat/h, thereby reducing the iron that is in a positive oxidation step in the catalyst.
US08513310B2	Cosmetic use of phytosphingosine as slimming agent and cosmetic compositions comprising phytosphingosine The invention relates to novel cosmetic uses of phytosphingosine or of one of its cosmetically acceptable salts, particularly its hydrochloride, as a slimming agent and/or as an active agent which stimulates the synthesis of leptin by adipocytes, for preparing a cosmetic composition intended for reducing subcutaneous excess fat.The invention also relates to a method of cosmetic treatment intended for obtaining a slimming effect on the human body according to which a cosmetic composition containing phytosphingosine or one of its cosmetically acceptable salts, particularly its hydrochloride, is applied on the parts of the body to be treated.The invention also relates to novel cosmetic compositions containing phytosphingosine or one of its cosmetically acceptable salts, particularly its hydrochloride, in combination with a lipolytic agent selected from the group consisting of CAMP and its derivatives, adenylate cyclase enzyme activating agents and phosphodiesterase enzyme inhibiting agents.
US08513308B2	PAK1 agonists and methods of use The present invention is directed to Pak1 agonists and methods of use.
US08513307B2	N-phenylacetamide inhibitors of the enzyme SOAT-1 and pharmaceutical/cosmetic compositions comprised thereof Novel N-phenylacetamide compounds of formula (I): and cosmetic and pharmaceutical compositions containing same are useful for treating disorders of the sebaceous gland, e.g., acne, or have cosmetic applications.
US08513306B2	Enhancement of urogenital function A method of treating nocturia in a human individual includes administering dosages of creatine to the individual; and reducing the dosages of creatine to the individual responsive to an increase in difficulty of the individual to initiate urination. Another example method includes reducing the dosages of creatine to the individual responsive to an increase in nocturnal urination frequency of the individual. A dosing system includes doses of creatine for treating nocturia in a human individual and is configured for reduced doses for administration in response to an increase in one or more nocturia symptoms. Various other methods as well as compositions, systems, etc., are also disclosed.
US08513304B2	Topical formulation It has been discovered that certain combinations of compounds are excellent penetration enhancers and, as such, can be incorporated in a topical formulation to facilitate administration of active agents. The increased penetration enhancement can also lead to a reduction in the total concentration of skin irritants in the formulation. There is described herein a topical formulation comprising (i) an active agent selected from at least one of lidocaine and tetracaine; (ii) a first compound, and (iii) a second compound, wherein the first compound and second compound are different, and each is selected from the group consisting of N-lauroyl sarcosine, sodium octyl sulfate, methyl laurate, isopropyl myristate, oleic acid, glyceryl oleate and sodium lauryl sulfoacetate.
US08513292B2	Compositions and methods for the treatment of cancer The present invention relates to pyrrolidine-2,5-dione compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrrolidine-2,5-dione compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a compound or pyrrolidine-2,5-dione compound of the present invention. (Ia) (Ib) (IIa) (IIIb) Where U is independently selected from: (I) or (II) where U is independently selected from:
US08513291B2	Cytochrome P450 inhibitors and uses thereof The present invention provides compounds having the general structural formula (I) and pharmaceutically acceptable derivatives thereof, as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases involving fibrosis and proliferation, and where anti-fibrotic or anti-proliferative activity is beneficial.
US08513286B2	Iminipyridine derivatives and their uses as microbiocides Compounds of the formula (I) in which the substituents are as defined in claim 1 are suitable for use as microbiocides.
US08513285B2	3 or 4-substituted piperidine compounds There are disclosed racemic or enantiomerically enriched 3- or 4-substituted piperidine compounds represented by the following structural formula (I): or any of their isomers, or pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions containing the subject compounds. The subject compounds are useful for the treatment of diseases of the central nervous system, particularly depression, anxiety and pain disorder.
US08513282B2	Modulators of cystic fibrosis transmembrane conductance regulator The present invention relates to modulators of cystic fibrosis transmembrane conductance regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using modulators of CFTR.
US08513276B2	Imidazo[1,2-a]pyridine compounds for use in treating cancer The invention relates to new bicyclic heterocyclic derivative compounds of Formula (I), to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer. The compounds of Formula (I) are inhibitors of FGFR, VEGFR or PDGFR.
US08513275B2	Forms of rifaximin and uses thereof The present invention relates to new rifaximin forms kappa, theta, rifaximin:piperazine cocrystal 1 and rifaximin:piperazine cocrystal 2, methods of making same and to their use in medicinal preparations and therapeutic methods.
US08513273B2	Arylethynyl derivatives The present invention relates to ethynyl compounds of formula I wherein R1, R2, R2′, R3, R3′, R4, R4′, U, V, W, Y, m, and n are as defined herein and to a pharmaceutically acceptable acid addition salts, to a racemic mixtures, or to its corresponding enantiomers and/or optical isomers and/or stereoisomers thereof. Compounds of formula I are allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5).
US08513269B2	Preparation for external use A compound represented by the formula (I), salt thereof, or hydrate thereof has an excellent anti-pruritic effect and an excellent effect in terms of metabolism. The topical formulation of the present invention has excellent skin absorption properties of the compound represented by the formula (I), salt thereof, or hydrate thereof. Furthermore, the topical formulation of the present invention is excellent in stability because ingredients are hardly bled after long-term storage. wherein R represents hydroxyl, C1-6 alkoxy optionally substituted with C1-6 alkoxy, or amino optionally substituted with C1-6 alkyl.
US08513267B2	4-anilinoquinazoline derivatives with adenosine-kinase inhibitor properties The present invention relates to the use of 4-anilinoquinazoline derivatives as adenosine-kinase inhibitors. The present invention also relates to a method for protecting tissues and organs like heart, brain and kidneys affected by ischemia, and for treating heart insufficiency, myocardium infarct, arrhythmia, arterial hypertension, atherosclerosis, coronary artery restenosis after angioplasty, chronic renal insufficiency, cerebral vascular accident, and chronic inflanunatory diseases (e.g., rheumatoid arthritis). The present invention also relates to the compound 6,7-dimethoxy-4-(3′-N′,N′-dimethylaminoanilino)quinazoline, or a pharmaceutically acceptable salt thereof, pharmaceutical composition comprising it and use of such compound in the manufacture of a medicament for treating or preventing diseases or conditions that are benefited from the adenosine-kinase inhibition.
US08513264B2	Combination therapy for the treatment of diabetes and related conditions The present invention relates to combinations of DPP-4 inhibitors with GPR119 agonists, as well as to the use of these combinations for treating and/or preventing metabolic diseases, particularly diabetes (especially type 2 diabetes mellitus) and conditions related thereto.
US08513262B2	Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors A process for the preparation of a compound of formula (I) comprising the steps: (a) reacting a compound of formula (II) wherein L and L′ are suitable leaving groups, with a compound of formula (III) UNH2 (III) to prepare a compound of formula (IV) and subsequently (b) substituting the group R1 by replacement of the leaving group L′.
US08513255B2	Substituted dihydroquinazolines The invention relates to substituted dihydroquinazolines and to processes for their preparation and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular for use as antiviral agents, in particular against cytomegalo viruses.
US08513245B2	Pharmaceutical composition for reducing the area of myocardial infarction and its use This invention relates to a pharmaceutical composition for preventing and curing myocardium ischemia and reducing area of myocardial infarction, its pharmaceutical preparation and applications. The composition includes (a) levocarnitine or its derivatives, and (b) trimetazidine or its medicative salts. The quantity of levocarnitine or its derivatives, and trimetazidine or its medicative salts in the composition is effective amount for treating myocardial ischemia and reducing the area of myocardial infarction.
US08513242B2	Pyrimidine compounds and methods of making and using same Disclosed herein are pyrimidinyl compounds that are contemplated to be modulators of cystic fibrosis transmembrane regulators (CFTR), and methods of making and using same. Also provided are pharmaceutical compositions and methods of treating disorders associated with cystic fibrosis transmembrane regulators, such as airway inflammation, cystic fibrosis, and the like.
US08513240B2	Micronized tanaproget and compositions containing same The present invention provides compositions, desirably pharmaceutical compositions, containing micronized tanaproget. The compositions can also contain microcrystalline cellulose, croscarmellose sodium, anhydrous lactose, and magnesium stearate; or can contain microcrystalline cellulose, croscarmellose sodium, sodium lauryl sulfate, povidone, and magnesium stearate. The compositions are useful in contraception and hormone replacement therapy and in the treatment and/or prevention of uterine myometrial fibroids, benign prostatic hypertrophy, benign and malignant neoplastic disease, dysfunctional bleeding, uterine leiomyomata, endometriosis, polycystic ovary syndrome, and carcinomas and adenocarcinomas of the pituitary, endometrium, kidney, ovary, breast, colon, and prostate and other hormone-dependent tumors, and in the preparation of medicaments useful therefor. Additional uses include stimulation of food intake.
US08513239B2	Chiral cis-imidazolines There are provided compounds of the formula or the pharmaceutically acceptable salts thereof, wherein X, Y, Z, V1, V2, R1, R2, R3, R4 and R5 are herein described. These compounds are useful as anticancer agents.
US08513235B2	Homocysteine synthase inhibitor The invention provides a homocysteine synthase inhibitor useful for the prophylaxis or treatment of diseases involving homocysteine synthase. The homocysteine synthase inhibitor is a compound of the formula (I) wherein each symbol is as defined herein, or a pharmacologically acceptable salt thereof, or a solvate thereof.
US08513233B2	Pyrimidinyl-propionic acid derivatives and their use as PPAR agonists The present invention disclosed compounds of Structural Formula (I), and enantiomer, racemic body, pharmaceutically acceptable salts, solvates or hydrates thereof, wherein variable groups are as defined within, as well as methods for preparing such compounds. The compounds are useful as PPARγ agonist, through activating PPAR-RXR heterodimers that interacts with specific DNA response elements within promoter regions of target gene, particularly in the treatment and prevention of polycystic kidney and cancer.
US08513229B2	4-Azetidinyl-1-phenyl-cyclohexane antagonists of CCR2 The present invention comprises compounds of Formula (I): wherein: X, R1, R2, R3, and R4 are as defined in the specification. The invention also comprises a method of preventing, treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is type II diabetes, obesity and asthma. The invention also comprises a method of inhibiting CCR2 activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula (I).
US08513224B2	Crystalline form C of tigecycline dihydrochloride and methods for its preparation The present invention relates to crystalline form C of Tigecycline dihydrochloride and to methods for the preparation of the same. Furthermore the present invention relates to the use of crystalline form C of Tigecycline dihydrochloride as an intermediate for the preparation of an anti-infective medicament. Moreover the present invention relates to pharmaceutical compositions comprising crystalline form C of Tigecycline dihydrochloride in an effective amount and to the use of crystalline form C of Tigecycline dihydrochloride as an anti-infective medicament.
US08513223B2	Substituted tetracycline compounds for treatment of inflammatory skin disorders Methods and compositions for the treatment of skin disorders (e.g., acne, rosacea) are described.
US08513217B2	Biopolymer system for tissue sealing A tissue sealant for use in surgical and medical procedures for sealing the tissues of a living mammal is provided. The tissue sealant comprises a hydrogel which is formed by gelation of a premix disposed on the tissue to be sealed. The premix comprises alkylated chitosan or a gelatin, and a polybasic carboxylic acid or an oxidized polysaccharide, in an aqueous medium. The premix can also include a dehydrating reagent, a carboxyl activating reagent, or both. A specific use of the tissue sealant is in the repair of the dura mater after brain surgery to prevent leakage of cerebrospinal fluid. The tissue sealant may include a therapeutic or protective agent such as an antibiotic or an anti-inflammatory drug.
US08513216B2	Polysaccharide gel formulation having increased longevity Described herein are polysaccharide gel formulations including at least one inhibitor of polysaccharide degradation and methods of making the same. The methods described herein involve the steps of providing at least one polysaccharide and incorporating at least one inhibitor of degradation into the polysaccharide. In some embodiments, the incorporating step comprises 1) mixing the at least one inhibitor with the at least one polysaccharide at a highly hydrated state thereby encapsulating the at least one inhibitor in a polysaccharide network, and 2) dehydrating the polysaccharide network thereby controlling release kinetics or final swell ratio. In another embodiment, the incorporating step comprises 1) encapsulating at least one inhibitor into a biocompatible or biodegradable vessel and 2) combining the polysaccharide and the vessel into a gel formulation. The polysaccharide gel formulations described herein can be used for a variety of cosmetic applications.
US08513215B2	Compositions for the treatment or prophylaxis of viral infections A compound of the general formula (III): wherein X is O, S, NH or CH2; Y is O, S or NH; Z is O, S or CH2; R1 is C1-8 alkyl, especially C1-6 alkyl, preferably n-alkyl, e.g., n-pentyl or n-hexyl; at least one of R2 and R3 is H—[R4-R5]n—R6—, in which: H—[R4-R5]n— comprises an oligopeptide, R4 being an amino acid and R5 being an amino acid selected from proline, alanine, hydroxyproline, dihydroxyproline, thiazolidinecarboxylic acid (thioproline), dehydroproline, pipecolic acid (L-homoproline), azetidinecarboxylic acid, aziridinecarboxylic acid, glycine, serine, valine, leucine, isoleucine and threonine, R6 is a neutral, non-polar amino acid moiety that is bonded to R5 by a peptide bond, and n is 1, 2, 3, 4 or 5; and the other of R3 and R2 is H—[R4-R5]n-R6— or H; or a pharmaceutically acceptable salt thereof.
US08513214B2	C4′-substituted-2-deoxyadenosine analogs and methods of treating HIV The invention provides for novel 2-Deoxyadenosine compounds, which can treat HIV infection at low cytotoxicity values. Substitution at the 4′-position provided compounds which demonstrated low cytotoxicity values in an ATP-based cytotoxicity assay.
US08513213B2	SDF-1 delivery for treating ischemic tissue A method of treating a cardiomyopathy in a subject includes administering directly to or expressing locally in a weakened, ischemic, and/or peri-infarct region of myocardial tissue of the subject an amount of SDF-1 effective to cause functional improvement in at least one of the following parameters: left ventricular volume, left ventricular area, left ventricular dimension, cardiac function, 6-minute walk test, or New York Heart Association (NYHA) functional classification.
US08513212B2	Bruton's tyrosine kinase as anti-cancer drug target Receptor protein tyrosine kinases (RPTKs) transmit extracellular signals across the plasma membrane to cytosolic proteins, stimulating formation of complexes that regulate key cellular functions. Over half of the known tyrosine kinases are implicated in human cancers and are therefore highly promising drug targets. A large-scale loss-of-function analysis of the tyrosine kinases using RNA interference in the clinically relevant Erb-B2 positive, BT474 breast cancer cell line showed that Bruton's tyrosine kinase (BTK), a cytosolic, non-receptor tyrosine kinase that has been extensively studied for its role in B cell development, is required, in altered form, for BT474 breast cancer cell survival. This alternative form contains an amino-terminal extension that is also present in tumorigenic breast cells at significantly higher levels than in normal breast cells.
US08513208B2	Transient expression of immunomodulatory polypeptides for the prevention and treatment of autoimmune disease, allergy and transplant rejection A method is provided for treating or preventing an undesired immune response in a patient, comprising: administering to said patient, cells that transiently express, and/or that are transfected with mRNA encoding, one or more polypeptides selected from the group consisting of an IL-4 receptor agonist, an IFN-γ receptor antagonist, an IFN-α receptor antagonist, an IL-12 receptor antagonist, an IL-23 receptor antagonist, and a TNF antagonist. Preferably, the cells selectively accumulate in one or more secondary lymphoid tissues at or proximate to the site of the undesired immune response. Related compositions are provided. The methods and compositions are useful for the treatment or prevention of undesired immune responses including, but not limited to, transplant rejection, autoimmune disease, allergy and immune responses directed against therapeutic compositions.
US08513202B2	Crystalline form of 1-(β-D-glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl]benzene hemihydrate A novel crystal form of 1-(β-D-glucopyranosyl)-4-methyl-3-[5-(4-fluorophenyl)-2-thienylmethyl]benzene hemihydrate, and having favorable characteristics, is characterized by its x-ray powder diffraction pattern and/or by its infra-red spectrum.
US08513201B2	Modified chaperonin 10 The present invention relates to isolated Chaperonin 10 polypeptides possessing immunomodulatory activity, but lacking, or substantially lacking, protein folding activity.
US08513198B2	Pharmaceutical formulation for reducing pain The present invention is directed to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyl, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the ω-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound. A preferred route of administration is intrathecal administration, particularly continuous intrathecal infusion. The present invention is also directed to a pharmaceutical formulation comprising an omega conopeptide, preferably ziconotide, an antioxidant, in combination with an analgesic selected from the group consisting of morphine, bupivacaine, clonidine, hydromorphone, baclofen, fentanyl, buprenorphine, and sufentanil.
US08513195B2	Treatment of mood and anxiety disorders The invention relates to a selective inhibitor of Elk-1 or MSK-1 activation for use in the prevention and/or treatment of mood and anxiety disorders.
US08513190B2	Method of regulating glucose metabolism, and reagents related thereto The present invention provides methods for modification and regulation of type II diabetes by administering to an animal a therapeutically effective amount of an inhibitor of dipeptidylpeptidase IV (DPIV) or a pharmaceutically acceptable salt thereof, where the inhibitor has a Ki for inhibition of DPIV of 10 nM or less; and the inhibitor is administered in an amount sufficient to treat type II diabetes but not sufficient to suppress the immune system of the animal.
US08513188B2	Formulations comprising cyclic compounds This invention relates to the use of a cyclic compound of formula (I) wherein A, B independently in each occurrence is alkane-i,j-diyl having k carbon atoms, i and independently j being less than or equal k and k being selected from 1 to 10, wherein said alkane-i,j-diyl (i) may comprise one or more double bonds; (ii) is optionally substituted; and/or (iii) comprises a cycle, wherein the total number of cycles being cyclic sugars in said compound is selected from 0 to 4 and is less than p·(n+m); X,Y independently in each occurrence is a biocompatible functional group comprising at least one oxygen atom or two sulphur atoms; n, m independently of each other are selected from 0 to 20; p is selected from 1 to 10; n+m is equal or greater than 1; and p·(n+m) is selected from 3 to 30; wherein said compound is capable of forming a complex with a protonated primary and/or protonated secondary amino group and/or a protonated guanidinium group for the manufacture of a pharmaceutical or diagnostic composition.
US08513185B2	Inhibition of TREM receptor signaling with peptide variants Peptides are provided consisting of L- and/or D-amino acids and combinations thereof, which affect myeloid cells by action on the triggering receptors expressed on myeloid cells (TREMs), including TREM-1 and TREM-2. The peptides act on the TREM/DAP-12 signaling complex. Also provided are lipid and sugar conjugated peptides comprising L- or D-amino acids. A method is provided of designing the peptides and lipid- and/or sugar-conjugated peptides comprising L- or D-amino acids. The disclosure relates to the therapy of various myeloid cell-related disease states involving the use of these peptides and compounds. The peptides and compounds are useful in the treatment and/or prevention of a disease or condition where myeloid cells are involved or recruited. The peptides of the present invention also are useful in the production of medical devices comprising peptide matrices (for example, medical implants and implantable devices).
US08513182B2	Natural polypeptides for oral health care The present invention relates generally to dental diseases, caries and periodontal disease. More specifically, the invention relates to Lactoferrin and Statherin fusion proteins (STAT-LF) along with therapeutic, diagnostic and research uses for these polypeptides. The present invention also provides methods of treating dental diseases, caries and periodontal disease.
US08513175B2	Alpha-amylase mutants The invention relates to a variant of a parent Termamyl-like alpha-amylase, which variant has alpha-amylase activity and exhibits an alteration in at least one of the following properties relative to the parent alpha-amylase: substrate specificity, substrate binding, substrate cleavage pattern, thermal stability, pH/activity profile, pH/stability profile, stability towards oxidation, Ca2+ dependency and specific activity.
US08513174B2	Cleanser The present invention provides a cleanser which is excellent in both of the foaming property and the cleansing capability. The cleanser comprises an organosiloxane derivative salt represented by the following formula (1) or (3) and one or more anionic surfactants selected from a group consisting of carboxylate salt with an alkyl group having 10 to 20 carbon atoms, sulfate salt with an alkyl group having 10 to 20 carbon atoms, sulfonate salt with an alkyl group having 10 to 20 carbon atoms, and phosphate salt with an alkyl group having 10 to 20 carbon atoms.
US08513172B2	Process for preparing polymers and compositions thereof The present invention provides a process for preparing a polymer, employing the steps of: (1) contacting a free radical initiator; a chain transfer agent containing a thiocarbonyl thio group and a free radical leaving group; and a radically polymerisable monomer, to form a polymer chain; and (2) contacting the polymer chain of step (1) with at least one of a polyvalent coupling agent, a polymerization inhibitor, a grafting acylating agent, an amine and an oil of lubricating viscosity. The invention further provides compositions and uses for the polymer.
US08513171B2	Lubricant composition, speed reduction gear, and electric power steering apparatus A lubricant composition, which is low in friction, does not have an attacking property against polyamide resin, etc., is excellent in heat resistance, and especially does not undergo deterioration or loss of the respective characteristics in a short term when used under a high temperature environment, is provided along with a speed reduction gear and an electric power steering apparatus that use the lubricant composition. The lubricant composition has blended therein a synthetic hydrocarbon oil, a urea thickener, zinc stearate, and a sulfur-based antioxidant. A speed reduction gear has a portion of engagement of a small gear and a large gear filled with the lubricant composition. In an electric power steering apparatus, an output of a steering assisting electric motor is speed reduced and transmitted to a steering mechanism via the speed reduction gear.
US08513170B2	Solid lubricant and production method thereof A method for producing a solid lubricant includes steps of preparing and coating. A phosphate aqueous solution prepared by the step of preparing is an aqueous solution containing at least one of aluminum dihydrogen phosphate and magnesium dihydrogen phosphate in an amount of 0.5 to 10% by mass. A graphite material is coated with a phosphate using the phosphate aqueous solution. The graphite material is used at a ratio of 40 to 50 parts by mass based on 100 parts by mass of the aqueous solution.
US08513166B2	Low temperature hydrocarbon gel A composition useful for crosslinking phosphate esters in hydrocarbon gels used in formation fracturing performs especially well in cold temperatures, such as temperatures lower than (−)20° C. Methods of making the crosslinking composition and the gel are described; also methods of fracturing subterranean formations. Specific forms of ferric sulfate and ferric ammonium citrate are useful as ingredients of the crosslinking composition.
US08513164B2	Protein (poly)peptides libraries The present invention relates to a method of identifying one or more genes encoding one or more proteins having an optimized property. In particular, the method comprises expressing a collection of genes and screening for a desired property, identifying a plurality of genes having the desired property, and replacing one or more one or more sub-sequences of each of said genes with a different, compatible genetic sub-sequence, and screening again in order to identify genes encoding proteins having an optimized property.
US08513163B2	Substrate for a superconducting thin-film strip conductor A high-temperature superconducting thin-film strip conductor (HTSL-CC) includes a metal substrate, a buffer layer chemically generated thereon and grown crystallographically unrotated in relation to the metal substrate, and a chemically generated superconducting coating thereon. The HTSL-CC possesses high texturing of the buffer layer since the metal substrate has a surface roughness RMS<50 nm, and since and the buffer layer is grown directly onto its surface, without an intermediate layer, crystallographically unrotated in relation to the crystalline structure of the metal substrate.
US08513160B2	Heat-sensitive recording material and method for producing same The present invention provides a heat-sensitive recording material that has high gloss and excellent absorption and scratch off properties against sebum soiling; and a method for producing the heat-sensitive recording material. More specifically, the present invention provides a heat-sensitive recording material containing a heat-sensitive recording layer, an intermediate layer, and a protective layer, which are sequentially formed in this order on a support. The heat-sensitive recording layer contains a leuco dye and a developer; the intermediate layer contains an aqueous adhesive; and the protective layer is cured by irradiation of an ultraviolet- or electron-beam-curable resin composition with ultraviolet light or an electron beam. The heat-sensitive recording material additionally contains, on the protective layer, an uppermost layer which contains an aqueous adhesive and a pigment having a mean particle diameter of not more than 100 nm. The uppermost layer-side surface of the heat-sensitive recording material has a gloss at 75° of not less than 90% and a gloss at 20° of not less than 35% in accordance with JIS P 8142-1993. The present invention further provides a method for producing the heat-sensitive recording material.
US08513157B2	Deactivation resistant photocatalysts The present disclosure relates to a fluid purification device that has a deactivation resistant photocatalyst having nanocrystallites of less than 14 nanometers (nm) in diameter with at least 200 m2 surface area/cm3 of skeletal volume in cylindrical pores of 5 nm in diameter or larger, with the mode of the pore size distribution 10 nm or more.
US08513153B2	Fuel additive Described are catalyst compositions and methods for their preparation and use. Certain catalyst compositions can include at least one reduction catalyst and at least one oxidation catalyst. A catalyst composition as described herein is useful in providing certain benefits to a combustible fuel, such as, for example, reducing harmful emissions and/or improving overall fuel economy.
US08513150B2	Extra mesoporous Y zeolite This invention relates to the composition and synthesis of an Extra Mesoporous Y (or “EMY”) zeolite and its use in the catalytic conversion of organic compounds. In particular, this invention relates to a Y-type framework zeolite possessing a high large mesopore pore volume to small mesopore pore volume ratio. The novel zeolite obtained provides beneficial structural features for use in petroleum refining and petrochemical processes.
US08513147B2	Nonwovens produced from multicomponent fibers A water non-dispersible polymer microfiber is provided comprising at least one water non-dispersible polymer wherein the water non-dispersible polymer microfiber has an equivalent diameter of less than 5 microns and length of less than 25 millimeters. A process for producing water non-dispersible polymer microfibers is also provided, the process comprising: a) cutting a multicomponent fiber into cut multicomponent fibers; b) contacting a fiber-containing feedstock with water to produce a fiber mix slurry; wherein the fiber-containing feedstock comprises cut multicomponent fibers; c) heating the fiber mix slurry to produce a heated fiber mix slurry; d) optionally, mixing the fiber mix slurry in a shearing zone; e) removing at least a portion of the sulfopolyester from the multicomponent fiber to produce a slurry mixture comprising a sulfopolyester dispersion and water non-dispersible polymer microfibers; and f) separating the water non-dispersible polymer microfibers from the slurry mixture. A process for producing a nonwoven article is also provided.
US08513146B2	Scalloped oval bicomponent fibers with good wicking, and high uniformity spun yarns comprising such fibers The invention provides a polyester bicomponent staple fiber comprising poly(trimethylene terephthalate) and at least one polymer selected from the group consisting of poly(ethylene terephthalate), poly(trimethylene terephthalate), and poly(tetramethylene terephthalate) or a combination of such members, said bicomponent staple fiber having: a) a scalloped oval cross-section shape having an aspect ratio a:b of about 2:1 to about 5:1 wherein ‘a’ is a fiber cross-section major axis length and ‘b’ is a fiber cross-section minor axis length; b) a polymer interface substantially perpendicular to the major axis; c) a cross-section configuration selected from the group consisting of side-by-side and eccentric sheath-core; d) a plurality of longitudinal grooves; and e) a groove ratio of about 1.05:1 to about 1.9:1. Additionally, the invention provides a spun yarn comprising cotton and the polyester bicomponent staple fiber of the invention, as well as fabrics and garments comprising the spun yarn of the invention.
US08513143B2	Semiconductor structure and method of manufacturing The present application discloses a method of manufacturing a semiconductor structure. According to at least one embodiment, a first etch stop layer is formed over a conductive feature and a substrate, and the conductive feature is positioned over the substrate. A second etch stop layer is formed over the first etch stop layer. A first etch is performed to form an opening in the second etch stop layer, and the opening exposes a portion of the first etch stop layer. A second etch is performed to extend the opening downwardly by removing a portion of the exposed first etch stop layer, and the extended opening exposes a portion of the conductive feature.
US08513142B2	Method of manufacturing non-photosensitive polyimide passivation layer A method of manufacturing non-photosensitive polyimide passivation layer is disclosed. The method includes: spin-coating a non-photosensitive polyimide layer over a wafer and baking it; depositing a silicon dioxide thin film thereon; spin-coating a photoresist layer over the silicon dioxide thin film and baking it; exposing and developing the photoresist layer to form a photoresist pattern; etching the silicon dioxide thin film by using the photoresist pattern as a mask; removing the patterned photoresist layer; dry etching the non-photosensitive polyimide layer by using the patterned silicon dioxide thin film as a mask; removing the patterned silicon dioxide thin film; and curing to form a imidized polyimide passivation layer. The method addresses issues of the traditional non-photosensitive polyimide process, including aluminum corrosion by developer, tapered profile of non-photosensitive polyimide layer and generation of photoresist residues.
US08513139B2	Etching agent, etching method and liquid for preparing etching agent The present invention is directed to provide an etching agent for a semiconductor substrate, which is capable of etching a titanium (Ti)-based metal film or a tungsten (W)-based metal film on a semiconductor substrate and an etching method using relevant etching agent, and relates to a liquid for preparing the etching agent for a semiconductor substrate composed of a solution comprising (A) hydrogen peroxide, (B) a phosphonic acid chelating agent having a hydroxyl group, (C) a basic compound, and (D-1) a copper anticorrosive and/or (D-2) 0.01 to 3% by weight of two or more kinds of anion species other than phosphonic acid chelating agents having a hydroxyl group, in which anion species have no oxidizing power, an etching method characterized by etching a titanium (Ti)-based metal film or a tungsten (W)-based metal film on a semiconductor substrate using relevant etching agent for a semiconductor substrate, further, a solution comprising (B) a phosphonic acid chelating agent having a hydroxyl group, (C) a basic compound, and (D-1) a copper anticorrosive and/or (D-2) anion species other than phosphonic acid chelating agents having a hydroxyl group, in which anion species have no oxidizing power.
US08513135B2	Methods of modifying oxide spacers Methods for reducing line roughness of spacers and other features utilizing a non-plasma and non-wet etch fluoride processing technology are provided. Embodiments of the methods can be used for spacer or line reduction and/or smoothing the surfaces along the edges of such features through the reaction and subsequent removal of material.
US08513133B2	Composition for forming resist underlayer film and method for forming pattern A resist underlayer film-forming composition includes (A) a polymer that includes a repeating unit shown by a formula (1), and has a polystyrene-reduced weight average molecular weight of 3000 to 10,000, and (B) a solvent, wherein R3 to R8 individually represent a group shown by the following formula (2) or the like, —O—R1≡R2 (2) wherein R1 represents a single bond or the like, and R2 represents a hydrogen atom or the like.
US08513129B2	Planarizing etch hardmask to increase pattern density and aspect ratio Methods for manufacturing a semiconductor device are provided. In one embodiment, a method includes providing a base material having a first film stack deposited thereon, wherein the base material is formed over the substrate and has a first set of interconnect features. The first film stack comprises a first amorphous carbon layer deposited on a surface of the base material, a first anti-reflective coating layer deposited on the first amorphous carbon layer, and a first photoresist layer deposited on the first anti-reflective coating layer. The first photoresist layer is patterned by shifting laterally a projection of a mask on the first photoresist layer relative to the substrate a desired distance, thereby introducing into the first photoresist layer a first feature pattern to be transferred to the underlying base material, wherein the first feature pattern is not aligned with the first set of interconnect features.
US08513126B2	Slurry composition having tunable dielectric polishing selectivity and method of polishing a substrate A chemical mechanical polishing slurry composition is provided, having, as initial components: water; an abrasive, wherein the abrasive is colloidal silica abrasive; a halogenated quaternary ammonium compound according to formula (I); optionally, a diquaternary substance according to formula (II); and, optionally, a pH adjusting agent selected from phosphoric acid, nitric acid, sulfuric acid, hydrochloric acid, ammonium hydroxide and potassium hydroxide; wherein the chemical mechanical polishing slurry composition has a pH of 2 to <7. Also, provided are methods for making the chemical mechanical polishing slurry composition and for using the chemical mechanical polishing composition to polish a substrate.
US08513125B2	Manufacturing a microelectronic device comprising silicon and germanium nanowires integrated on a same substrate A method for manufacturing a device comprising a structure with nanowires based on a semiconducting material such as Si and another structure with nanowires based on another semiconducting material such as SiGe, and is notably applied to the manufacturing of transistors.
US08513122B2	Method and structure for differential silicide and recessed or raised source/drain to improve field effect transistor A method forms an integrated circuit structure. The method patterns a protective layer over a first-type field effect transistor and removes a stress liner from above a second-type field effect transistors. Then, the method removes a first-type silicide layer from source and drain regions of the second-type field effect transistor, but leaves at least a portion of the first-type silicide layer on the gate conductor of the second-type field effect transistor. The method forms a second-type silicide layer on the gate conductor and the source and drain regions of the second-type field effect transistor. The second-type silicide layer that is formed is different than the first-type silicide layer. For example, the first-type silicide layer and the second-type silicide layer can comprise different materials, different thicknesses, different crystal orientations, and/or different chemical phases, etc.
US08513120B2	Gold-tin etch using combination of halogen plasma and wet etch The present disclosure relates to an implantable medical device. The implantable medical device includes a component comprising a first substrate bonded to a second substrate. A method for forming the component includes removing a first portion of tin (Sn) from gold tin (AuSn) through a halogen plasma. A first portion of gold (Au) is exposed in response to removing the first portion of the Sn. The first portion of the Au through a wet etch. A second portion of the Sn is exposed in response to removing the first portion of Au.
US08513116B2	Atomic layer deposition of tungsten materials Embodiments of the invention provide a method for depositing tungsten-containing materials. In one embodiment, a method includes forming a tungsten nucleation layer over an underlayer disposed on the substrate while sequentially providing a tungsten precursor and a reducing gas into a process chamber during an atomic layer deposition (ALD) process and depositing a tungsten bulk layer over the tungsten nucleation layer, wherein the reducing gas contains hydrogen gas and a hydride compound (e.g., diborane) and has a hydrogen/hydride flow rate ratio of about 500:1 or greater. In some examples, the method includes flowing the hydrogen gas into the process chamber at a flow rate within a range from about 1 slm to about 20 slm and flowing a mixture of the hydride compound and a carrier gas into the process chamber at a flow rate within a range from about 50 sccm to about 500 sccm.
US08513115B2	Method of forming an interconnect structure having an enlarged region A method of forming an interconnect structure that may reduce or eliminate stress induced voids is provided. In an embodiment, a via is formed below a conductive line to provide an electrical connection to an underlying conductive region. The conductive line includes a widened region above the via. The widened region serves to reduce or eliminate stress induced voids between the via and the underlying conductive region. In another embodiment, one or more redundant lines are formed extending from a conductive region, such as a contact pad, such that the redundant line does not electrically couple the conductive region to an underlying conductive region. In a preferred embodiment, the redundant lines extend from a conductive region on a side adjacent to a side having a conductive line coupled to a via.
US08513114B2	Method for forming a dual damascene interconnect structure An improved method of forming a semiconductor device including an interconnect layer formed using multilayer hard mask comprising metal mask and dielectric mask is provided. To form the second opening pattern being aligned to the first pattern, after the multilayer hard mask is used at the first step, then the dielectric mask is used to form a damascene structure in an insulator layer at the second step followed by removing the metal mask.
US08513113B2	Methods of forming semiconductor constructions and assemblies The invention includes semiconductor assemblies having two or more dies. An exemplary assembly has circuitry associated with a first die front side electrically connected to circuitry associated with a second die front side. The front side of the second die is adjacent a back side of the first die, and a through wafer interconnect extends through the first die. The through wafer interconnect includes a conductive liner within a via extending through the first die. The conductive liner narrows the via, and the narrowed via is filled with insulative material. The invention also includes methods of forming semiconductor assemblies having two or more dies; and includes electronic systems containing assemblies with two or more dies.
US08513110B2	Processes and structures for beveled slope integrated circuits for interconnect fabrication The present invention discloses methods and apparatuses for the separations of IC fabrication and assembling of separated IC components to form complete IC structures. In an embodiment, the present fabrication separation of an IC structure into multiple discrete components can take advantages of dedicated IC fabrication facilities and achieve more cost effective products. In another embodiment, the present chip assembling provides high density interconnect wires between bond pads, enabling cost-effective assembling of small chip components. In an aspect, the present process provides a beveled slope of the components to facilitate interconnection bonding.
US08513109B2	Method of manufacturing an interconnect structure for a semiconductor device A method of manufacturing an interconnect structure for a semiconductor device having a device substrate is provided. The semiconductor device includes an electrically-conductive pad formed overlying the device substrate and an electrically-conductive platform formed overlying the electrically-conductive pad and enclosing a cavity. The electrically-conductive platform has a perimeter portion extending away from the electrically-conductive pad and a capping portion atop the perimeter portion. The semiconductor device also includes a cushioning material disposed in the cavity.
US08513107B2	Replacement gate FinFET devices and methods for forming the same A structure and method for replacement metal gate technology is provided for use in conjunction with semiconductor fins or other devices. An opening is formed in a dielectric by removing a sacrificial gate material such as polysilicon. The surfaces of the semiconductor fin within which a transistor channel is formed, are exposed in the opening. A replacement metal gate is formed by forming a diffusion barrier layer within the opening and over a gate dielectric material, the diffusion barrier layer formation advantageously followed by an in-situ plasma treatment operation. The treatment operation utilizes at least one of argon and hydrogen and cures surface defects in the diffusion barrier layer enabling the diffusion barrier layer to be formed to a lesser thickness. The treatment operation decreases resistivity, densifies and alters the atomic ratio of the diffusion barrier layer, and is followed by metal deposition.
US08513103B2	Method for manufacturing vertical transistor having buried junction A buried junction is formed in a vertical transistor of a semiconductor device. Wall bodies are formed from a semiconductor substrate, the wall bodies protruding while having a first side surface and a second side surface in the opposite side of the first side surface; forming a one side contact mask having an opening which selectively opens a portion of the first side surface of the wall body; and forming a first impurity layer and a second impurity layer surrounding the first impurity layer by diffusing impurities having different diffusivities into the portion of the first side surface exposed to the opening.
US08513102B2	Reduction of random telegraph signal (RTS) and 1/f noise in silicon MOS devices, circuits, and sensors The effects of random telegraph noise signal (RTS) or equivalently 1/f noise on MOS devices, circuits, and sensors is described. Techniques are disclosed for minimizing this RTS and low frequency noise by minimizing the number of ionized impurity atoms in the wafer, substrate, well, pillar, or fin behind the channel of the MOS transistors. This noise reduction serves to reduce the errors in devices, sensors, and analog integrated circuits and error rates in digital integrated circuits and memories.
US08513101B2	Method of synthesizing nanowires A method of synthesizing a nanowire. The method includes disposing a first oxide layer including germanium (Ge) on a substrate, forming a second oxide layer including a nucleus by annealing the first oxide layer, and growing a nanowire including Ge from the nucleus by a chemical vapor deposition (“CVD”) method.
US08513100B2	Semiconductor device manufacturing method and semiconductor device In a semiconductor device manufacturing method, an amorphous or microcrystalline metal oxide film is formed over a first metal film which is preferentially oriented along a predetermined crystal plane. After that, a ferroelectric film is formed by a MOCVD method. When the ferroelectric film is formed, the metal oxide film formed over the first metal film is reduced to a second metal film and the ferroelectric film is formed over the second metal film. When the ferroelectric film is formed, the amorphous or microcrystalline metal oxide film is apt to be reduced uniformly. As a result, the second metal film the orientation of which is good is obtained and the ferroelectric film the orientation of which is good is formed over the second metal film. After the ferroelectric film is formed, an upper electrode is formed over the ferroelectric film.
US08513091B2	Method for wafer bonding using gold and indium Devices, methods, and systems for wafer bonding are described herein. One or more embodiments include forming a bond between a first wafer and a second wafer using a first material adjacent the first wafer and a second material adjacent the second wafer. The first material includes a layer of gold (Au) and a layer of indium (In), and the second material includes a layer of Au. Forming the bond between the first wafer and the second wafer includes combining the layer of Au in the first material, the layer of In in the first material, and a portion of the layer of Au in the second material, wherein an additional portion of the layer of Au in the second material is not combined with the layer of Au in the first material and the layer of In in the first material.
US08513090B2	Method for manufacturing semiconductor substrate, and semiconductor device An object is to provide a novel manufacturing method of a semiconductor substrate containing silicon carbide, and another object is to provide a semiconductor device using silicon carbide. A semiconductor substrate is manufactured through the steps of: adding ions to a silicon carbide substrate to form an embrittlement region in the silicon carbide substrate; bonding the silicon carbide substrate to a base substrate with insulating layers interposed therebetween; heating the silicon carbide substrate and separating the silicon carbide substrate at the embrittlement region to form a silicon carbide layer over the base substrate with the insulating layers interposed between therebetween; and performing heat treatment on the silicon carbide layer at a temperature of 1000° C. to 1300° C. to reduce defects of the silicon carbide layer. A semiconductor device is manufactured using the semiconductor substrate formed as described above.
US08513089B2	Discontinuous thin semiconductor wafer surface features A semiconductor wafer has a semiconductor substrate and films on the substrate. The substrate and/or the films have at least one etch line creating a discontinuous surface that reduces residual stress in the wafer. Reducing residual stress in the semiconductor wafer reduces warpage of the wafer when the wafer is thin. Additionally, isolation plugs may be used to fill a portion of the etch lines to prevent shorting of the layers.
US08513087B2	Processes for forming isolation structures for integrated circuit devices Processes for forming isolation structures for semiconductor devices include forming a submerged floor isolation region and a filed trench which together enclose an isolated pocket of the substrate. One process aligns the trench to the floor isolation region. In another process a second, narrower trench is formed in the isolated pocket and filled with a dielectric material while the dielectric material is deposited so as to line the walls and floor of the first trench. The substrate does not contain an epitaxial layer, thereby overcoming the many problems associated with fabricating the same.
US08513084B2	Transistor structure with a sidewall-defined intrinsic base to extrinsic base link-up region and method of forming the transistor Disclosed are embodiments of a bipolar or heterojunction bipolar transistor and a method of forming the transistor. The transistor can incorporate a dielectric layer sandwiched between an intrinsic base layer and a raised extrinsic base layer to reduce collector-base capacitance Ccb, a sidewall-defined conductive strap for an intrinsic base layer to extrinsic base layer link-up region to reduce base resistance Rb and a dielectric spacer between the extrinsic base layer and an emitter layer to reduce base-emitter Cbe capacitance. The method allows for self-aligning of the emitter to base regions and incorporates the use of a sacrificial dielectric layer, which must be thick enough to withstand etch and cleaning processes and still remain intact to function as an etch stop layer when the conductive strap is subsequently formed. A chemically enhanced high pressure, low temperature oxidation (HIPOX) process can be used to form such a sacrificial dielectric layer.
US08513080B2	Reducing contamination in a process flow of forming a channel semiconductor alloy in a semiconductor device In sophisticated approaches for forming high-k metal gate electrode structures in an early manufacturing stage, a threshold adjusting semiconductor alloy may be deposited on the basis of a selective epitaxial growth process without affecting the back side of the substrates. Consequently, any negative effects, such as contamination of substrates and process tools, reduced surface quality of the back side and the like, may be suppressed or reduced by providing a mask material and preserving the material at least during the selective epitaxial growth process.
US08513075B2	Method for manufacturing a semiconductor device A manufacturing method for manufacturing a semiconductor device includes depositing a spacer material on a semiconductor substrate, the substrate includes an NMOS region and a PMOS region, each region has a gate formed thereon. The method further includes covering the NMOS region with a first mask, forming a spacer for the PMOS gate by etching the spacer material, forming a recess in the PMOS region by etching, and growing SiGe or SiGe with in-situ-doped B in the recess of the PMOS region to form a PMOS source/drain region. The method further includes performing an anisotropic wet etching on the recess. After growing SiGE or SiGe with in-situ-doped B, the method further includes covering the PMOS region with a second mask and forming a spacer for the NMOS gate by etching the spacer material. The spacer for the PMOS and NMOS gate has a different critical dimension.
US08513070B2	Methods of manufacturing wire, TFT, and flat panel display device A method of manufacturing a wire may include forming a wire pattern, which at least includes a first conductive layer, a second conductive layer, and a third conductive layer arranged in the order stated on a substrate. At least the second conductive layer may have higher etch selectivity than the first and third conductive layers. Side holes may be formed by removing portions of the second conductive layer at ends of the wire pattern, and fine wires may be formed by injecting a masking material into the side holes and patterning the wire pattern by using the masking material as a mask.
US08513069B2	Method for aligning elongated nanostructures A method of depositing elongated nanostructures that allows accurate positioning and orientation is described. The method involves printing or otherwise depositing elongated nanostructures in a carrier solution. The deposited droplets are also elongated, usually by patterning the surface upon which the droplets are deposited. As the droplet evaporates, the fluid flow within the droplets is controlled such that the nanostructures are deposited either at the edge of the elongated droplet or the center of the elongated droplet. The described deposition technique has particular application in forming the active region of a transistor.
US08513068B2	Nanowire field effect transistors A method for forming a nanowire field effect transistor (FET) device including forming a first silicon on insulator (SOI) pad region, a second SOI pad region, a third SOI pad region, a first SOI portion connecting the first SOI pad region to the second SOI pad region, and a second SOI portion connecting the second SOI pad region to the third SOI pad region on a substrate, patterning a first hardmask layer over the second SOI portion, forming a first suspended nanowire over the semiconductor substrate, forming a first gate structure around a portion of the first suspended nanowire, patterning a second hardmask layer over the first gate structure and the first suspended nanowire, removing the first hardmask layer, forming a second suspended nanowire over the semiconductor substrate, forming a second gate structure around a portion of the second suspended nanowire, and removing the second hardmask layer.
US08513065B2	Method for manufacturing display device A method of manufacturing a display device is disclosed. In one embodiment, the method includes: i) forming a semiconductor layer where a plurality of crystallized areas and a plurality of noncrystallized areas are alternately arranged on a substrate, ii) aligning the substrate based on a difference in contrast ratio between the crystallized and noncrystallized areas and iii) performing a photo process or a photolithography process.
US08513064B2	Methods of forming memory arrays Some embodiments include methods of forming memory arrays. A stack of semiconductor material plates may be patterned to subdivide the plates into pieces. Electrically conductive tiers may be formed along sidewall edges of the pieces. The pieces may then be patterned into an array of wires, with the array having vertical columns and horizontal rows. Individual wires may have first ends joining to the electrically conductive tiers, may have second ends in opposing relation to the first ends, and may have intermediate regions between the first and second ends. Gate material may be formed along the intermediate regions. Memory cell structures may be formed at the second ends of the wires. A plurality of vertically-extending electrical interconnects may be connected to the wires through the memory cell structures, with individual vertically-extending electrical interconnects being along individual columns of the array. Some embodiments include memory arrays incorporated into integrated circuitry.
US08513063B2	Method for encapsulating microelectronic devices According to an embodiment disclosed herein, a microelectronic device to be encapsulated is built on, or alternatively in, a substrate. The device is then coated with a sacrificial layer. A lid layer is deposited over the sacrificial layer, and then appropriately perforated to optimize the removal of the sacrificial layer. The sacrificial layer is then removed using one of several etching or other processes. The perforations in the lid layer are then sealed using a viscous sealing material, thereby fixing the environment that encapsulates the device. The sealing material is then cured or hardened. An optional moisture barrier may be deposited over the cured sealing layer to provide further protection for the encapsulation if needed.
US08513062B2	Method of manufacturing a semiconductor device with a carrier having a cavity and semiconductor device A method includes providing a carrier having a first cavity, providing a dielectric foil with a metal layer attached to the dielectric foil, placing a first semiconductor chip in the first cavity of the carrier, and applying the dielectric foil to the carrier.
US08513060B2	Manufacturing method using multi-step adhesive curing for sealed semiconductor device A method for forming a sealing body without cracks in manufacture of a semiconductor device having an external terminal formed through the use of an electrolysis plating method. A front surface of a semiconductor wafer is placed over a front surface of a first support heated to a first temperature. An adhesive sheet is then bonded to a back surface of the semiconductor wafer, after which the semiconductor wafer is subjected to heat treatment at a second temperature higher than the first temperature. After the semiconductor wafer and the adhesive sheet are cut along cutting regions, a plurality of semiconductor chips each having an adhesive patch bonded thereto are obtained. A mother substrate is placed over a front surface of a second support heated to a third temperature and the semiconductor chips are fixed to an upper surface of the mother substrate via the adhesive patch.
US08513051B2	Methods of forming phase-changeable memory devices including an adiabatic layer Phase-changeable memory devices include a lower electrode electrically connected to an impurity region of a transistor in a substrate and a programming layer pattern including a first phase-changeable material on the lower electrode. An adiabatic layer pattern including a material having a lower thermal conductivity than the first phase-changeable material is on the programming layer pattern and an upper electrode is on the adiabatic layer pattern.
US08513048B2	Image sensor and method of manufacturing the same An image sensor and a method of manufacturing the same are disclosed. A passivation layer on an interlayer dielectric layer has different thicknesses for neighboring pixels. Consequently, a phase of light incident on a pixel is out of phase with light incident on an adjacent pixel before it reaches a photodiode. As a result, diffraction of the incident light results in destructive interference between the pixels. Thus, cross talk between adjacent pixels can be prevented.
US08513044B2	Method for the manufacturing of thin film photovoltaic converter device So as to improve efficiency of a thin-film photovoltaic converter device, during manufacturing of which an intermediate product module is manufactured, which comprises deposition of at least one positively doped, at least one intrinsic and at least one negatively doped silicon-based layer, the addressed intermediate product module is subjected to an annealing step during which the module is subjected to a temperature of between 100° C. to 200° C. during a time span of half an hour to four hours.
US08513039B2	Method for fabricating semiconductor lighting chip A method for fabricating a semiconductor lighting chip includes steps of: providing a substrate; forming a first etching layer on the substrate; forming a connecting layer on the first etching layer; forming a second etching layer on the connecting layer; forming a lighting structure on the second etching layer; and etching the first etching layer, the connecting layer, the second etching layer and the lighting structure, wherein an etching rate of the first etching layer and the second etching layer is lager than that of the connecting layer and the lighting structure, thereby to form the connecting layer and the lighting structure each with an inverted frustum-shaped structure.
US08513037B2	Method of integrating slotted waveguide into CMOS process A method for integrating a slotted waveguide into a CMOS process is disclosed. A slot can be patterned on a SOI wafer by etching a first pad hard mask deposited over the wafer. The slot is then filled with a nitride plug material by depositing a second pad hard mask over the first pad hard mask. A waveguide in association with one or more electronic and photonic devices can also be patterned on the SOI wafer. The trenches can be filled with an isolation material and then polished. Thereafter, the first and second pad hard masks can be stripped from the wafer. The slot can once again be filled with the nitride plug material and patterned. After forming one or more electronic and photonic devices on the wafer using a standard CMOS process, a via can be opened down to the nitride plug and the nitride plug can then be removed.
US08513036B2	Photonic quantum ring laser and fabrication method thereof A photonic quantum ring (PQR) laser includes an active layer having a multi-quantum-well (MQW) structure and etched lateral face. The active layer is formed to be sandwiched between p-GaN and n-GaN layers epitaxially grown on a reflector disposed over a support substrate. A coating layer is formed over an outside of the lateral faces of the active layer, and upper electrode is electrically connected to an upper portion of the n-GaN layer, and a distributed Bragg reflector (DBR) is formed over the n-GaN layer and the upper electrode. Accordingly, the PQR laser is capable of oscillating a power-saving vertically dominant 3D multi-mode laser suitable for a low power display device, prevent the light speckle phenomenon, and generate focus-adjusted 3D soft light.
US08513034B2	Method of manufacturing layered chip package A method of manufacturing a layered chip package that includes a main body, and wiring disposed on a side surface of the main body. The main body includes a plurality of layer portions. The method includes fabricating a plurality of substructures, and completing the layered chip package by fabricating the main body using the plurality of substructures and by forming the wiring on the main body. Each substructure is fabricated through the steps of: fabricating a pre-substructure wafer including a plurality of pre-semiconductor-chip portions aligned; distinguishing between a normally functioning pre-semiconductor-chip portion and a malfunctioning pre-semiconductor-chip portion among the plurality of pre-semiconductor-chip portions included in the pre-substructure wafer; and forming electrodes connected to the normally functioning pre-semiconductor-chip portion and having respective end faces located in the side surface of the main body on which the wiring is disposed, without forming any electrode connected to the malfunctioning pre-semiconductor-chip portion.
US08513029B2	Discrete contact MR bio-sensor with magnetic label field alignment The invention describes a family of sensors for assaying macro-molecules and/or biological cells in solution. Each sensor has the form of a well (a hollow cylinder having a floor but no lid) or a trench whose walls comprise a plurality of GMR or TMR devices. Suitably shaped magnets located below each well's floor pull labeled particles into the well/trench and up against the inner wall where a field gradient orients them for optimum detection. Any unattached labels that happen to also be in the well/trench are removed through suitably sized holes in the floor.
US08513021B2	Control method of measuring apparatus and measuring apparatus A measuring apparatus has a master communication interface for sequentially transmitting an operation command issued by a CPU to a plurality of mechanism units used for measurement of an analyte. The measuring apparatus also has a slave communication interface, provided for each mechanism unit, for receiving the operation command and a plurality of driving circuits for deriving the mechanism units in accordance with the received operation command. The master communication interface broadcasts an operation start instructing signal to the plurality of mechanism units after sequentially transmitting operation commands respectively to the plurality of mechanism units, and triggered by the operation start instructing signal, the driving units of the plurality of mechanism units concurrently initiate execution of the operation commands.
US08513019B2	Apparatus and method for genetically transforming cells A fluid containing cells and free genetic material is acoustically coupled to a propulsion surface of a diaphragm. A blast-receiving surface of the diaphragm is acoustically coupled to an explosion chamber in which an explosive material is disposed. An ignition system ignites the explosive material in the explosion chamber to create a blast wave. The diaphragm transfers momentum from the blast wave to the fluid containing cells and free genetic material sufficient to cause the cells to take up the free genetic material.
US08513015B2	Laminin-entactin complex and cell culture article and methods thereof A cell culture system including: a substrate, a substrate coating, one or more live cells, and an overlay source. The substrate coating and overlay can be laminin, and laminin•entactin complex, respectively. Alternatively, the substrate coating and overlay can be laminin•entactin complex, and laminin, respectively. The cell culture system can further include liquid media and a protective cover. A method for making and using the system in cell culture articles and culture methods, as defined herein, is also disclosed.
US08513014B2	Method for fabricating foam scaffolds to culture cells Methods and apparatuses for using microfluidics to generate bubbles and using the generated bubbles to construct scaffolds and cell-holding structures for culturing biological samples or analytes. In one implementation, a scaffold for growing cells is provided to include a matrix of interconnected cavities formed from mixing a gas and a liquid containing a cross linkable material to produce a matrix of gas bubbles of substantially the same size and cross linking the cross linkable material to form a structure in which cells are grown. In another implementation, a scaffold apparatus for growing cells includes a ball of a cross linked material forming an exterior shell that encloses to form a hollow interior inside the ball and biological samples embedded in the external shell.
US08513012B2	Method for production of mast cells from stem cells Provided are methods for generating mast cells from pluripotent stem cells in vitro. Methods are disclosed for the differentiation of pluripotent cells, such as iPS cells and/or human embryonic stem cells, into mast cells. The resulting mast cells may be used for various purposes including screening cells for drug development and research. Growth factors which may be included in culture media according to the present invention include stem cell factor (SCF), FLT-3 ligand, thrombopoietin (TPO), interleukin-3 (IL-3), and/or interleukin-6 (IL-6).
US08513002B2	Devices and methods for dual excitation Raman spectroscopy Spectroscopic analysis systems and methods for analyzing samples are disclosed. An analysis system may contain an electromagnetic radiation source to provide radiation, a spectroscopic analysis chamber to perform a coherent Raman spectroscopy (e.g., stimulated Raman or coherent anti-Stokes Raman spectroscopy), and a radiation detector to detect radiation based on the spectroscopy. The chamber may have a resonant cavity to contain a sample for analysis, at least one window to the cavity to transmit the first radiation into the cavity and to transmit a second radiation out, a plurality of reflectors affixed to a housing of the cavity to reflect radiation of a predetermined frequency, the plurality of reflectors separated by a distance that is sufficient to resonate the radiation. The spectroscopic analysis system may be coupled with a nucleic acid sequencing system to receive a single nucleic acid derivative in solution and identify the derivative to sequence the nucleic acid.
US08513000B2	High-throughput cell transfection device and methods of using thereof Transfecting biology cells with nucleic acid molecules (DNA, siRNA) is an essential prerequisite in elucidating how genes function in complex cellular context and how their activities could be modulated for therapeutic intervention. Traditionally studies are carried out on a low throughput gene-by-gene scale, which has created a huge bottleneck in functional genomic study and drug discovery. Development of high-throughput cell transfection technology will permit functional analysis of massive number of genes and how their activities could be modulated by chemical or biological entities inside cells. This invention describes design, construction of device and apparatus for high throughput effective cell transfection. Procedures and protocols for using the device and apparatus are also described in the application. Novel methods of using the device in cell-based assays are also disclosed.
US08512998B2	Process for microalgae conditioning and concentration Conditioning and concentration of microalgae are accomplished by the process steps of grinding a dilute aqueous dispersion of microalgae in the presence of grinding media and then applying adsorptive bubble separation. This process is amenable to the use of dilute feed microalgal dispersions such as are encountered in the production of algal biomass for biofuel applications.
US08512996B2	Cell for preparing competent cell, method for preparing competent cell and bacterial strain of Escherichia coli The invention provides a cell for preparing competent cells, wherein the cell is capable of spontaneously accumulating self-producing trehalose therein and the cell is used for the preparation of competent cells. The invention also provides a method for preparing competent cells, including: culturing the cell for preparing the competent cell mentioned previously to obtain a cell suspension; placing the cell suspension into an ice bath; centrifuging the cell suspension to obtain a cell precipitate; mixing a transform reagent with the cell precipitate; and obtaining competent cells suspension.
US08512992B2	Degradable clostridial toxins The specification discloses Clostridial toxins or Clostridial toxin chimeras comprising an inactivation cleavage site, polynucleotide molecules encoding such toxins or chimeras, compositions comprising such toxins or chimeras, and method of producing such toxins or chimeras.
US08512991B2	Beta 1,4-galactosyltransferases with altered donor and acceptor specificities, compositions and methods of use The invention relates generally to beta (1,4)-galactosyltransferase I mutants having altered donor and acceptor specificities, and methods of use thereof. In addition, the invention relates to methods for synthesizing oligosaccharides using the beta (1,4)-galactosyltransferase I mutants and to using the beta (1,4)-galactosyltransferase I mutants to conjugate agents, such as therapeutic agents or diagnostic agents, to acceptor molecules.
US08512990B2	Catalytic domains from lysyl oxidase and LOXL2 Disclosed herein are amino acid sequences, and encoding nucleotide sequences, of isolated catalytic domains of the LOX and LOXL2 proteins from human and mouse. Methods for the preparation and use of these isolated catalytic domains are also provided.
US08512988B2	Microbial engineering for the production of chemical and pharmaceutical products from the isoprenoid pathway The invention relates to recombinant expression of a taxadiene synthase enzyme and a geranylgeranyl diphosphate synthase (GGPPS) enzyme in cells and the production of terpenoids.
US08512986B2	Enzymes for starch processing The present invention relates to polypeptides comprising a carbohydrate-binding module amino acid sequence and an alpha-amylase amino acid sequence as well as to the application of such polypeptides.
US08512985B2	Signal peptide for producing a polypeptide The present invention relates to a method for producing a polypeptide comprising using a signal peptide, to nucleic acid constructs comprising a first nucleotide sequence encoding the signal peptide and a second nucleotide sequence encoding a polypeptide which is foreign to the first nucleotide sequence. Furthermore, it also relates to expression vectors and host cells comprising the nuclei acid construct.
US08512982B2	Enhanced protein production in Bacillus The present invention relates to cells that have been genetically manipulated to have an altered capacity to express and/or produce proteins of interest. In particular, the present invention relates to modified host cells of Gram-positive microorganisms, such as Bacillus species that are capable of overexpressing ymaH. The invention encompasses polynucleotide constructs and expression vectors containing polynucleotide sequences that encode YmaH, and the modified host cells comprising them. In particular, the present invention relates to compositions and methods of overexpressing YmaH for enhancing the expression and production of proteins of interest (e.g., proteases) in Bacillus species.
US08512978B2	Methods and compositions for a microemulsion-based tissue treatment The invention is directed to methods and compositions for deparaffinizing paraffin-embedded biological samples for subsequent tissue staining. The compositions are microemulsions that may include water/oil/surfactant microemulsions, and optionally a cosurfactant. The microemulsions enable deparaffinization without the use of xylene or toluene, and also enable solvent exchange without the use of intermediary alcohol dehydration or alcohol rehydration compositions.
US08512976B2	Selective growth media Disclosed is a method of selectively inhibiting for growth of non-target cells in a mixed population of target and non-target cells, the method comprising the steps of: (a) contacting the mixed population with a selective agent which comprises a carrier moiety linked by a scissile linkage to a toxic moiety; wherein the selective agent is able to enter non-target cells in which the scissile linkage is cleaved, releasing the toxic moiety to exert a toxic effect on the non-target cells causing inhibition of the growth of the non-target cells, whereas the selective agent is unable to enter target cells and/or the scissile linkage is not cleaved in target cells and/or toxic moiety, if released from the selective agent, does not exert a toxic effect on the target cell; and (b) culturing the cells in conditions which allow for growth of non-inhibited cells.
US08512975B2	Method for detection and characterization of a microorganism in a sample using time dependent spectroscopic measurements The present invention provides a method for detecting, and characterizing a microorganism present in a blood culture medium whereby the method may be accomplished utilizing a time-dependent spectroscopic technique to obtain at least two measurements directly of a blood culture medium and correlating said measurements for the detection and characterization of a microorganism, that may be present in the blood culture.
US08512972B2	Crystal of hypoxia inducible factor 1 alpha prolyl hydroxylase The crystal structure of ligand-bound EGLN1 catalytic domain of prolyl hydroxylase is disclosed. These coordinates are useful in computer aided drug design for identifying compounds that regulate EGLN1 prolyl hydroxylase and thereby regulate HIF-regulated disorders.
US08512971B2	Compounds and methods of use thereof for assaying lysophospholipase D activity Fluorogenic lysophosphatidic acid derivatives which can be used as substrates in a continuous, fluorogenic assay that can be performed in microtiter plates. The assays permit measuring LysoPLD activity levels in normal events such as pregnancy or disease states such as cancer. In addition, the present invention can be adopted to high throughout screening (HTS) for identification of potential inhibitors of lysoPLD activity.
US08512966B2	Method for sensing a chemical The present invention relates to a method for detecting an analyte (10) in a sample, comprising the steps of: providing a transducer comprising a pyroelectric or piezoelectric element and electrodes which is capable of transducing a change in energy to an electrical signal, a first reagent immobilised on the transducer, and a second reagent (11) releasably bound to the first reagent and having a label attached thereto which is capable of absorbing electromagnetic radiation to generate energy by non-radiative decay, wherein either the first or second reagent has a binding site which allows binding to the other and which is capable of preferentially binding to the analyte or a derivative of the analyte; exposing the transducer to the sample thereby allowing the analyte or a derivative of the analyte to bind to the binding site and displace the second reagent; irradiating the sample with electromagnetic radiation; transducing the energy generated into an electrical signal; and detecting the electrical signal. The invention also provides a device for carrying out the method.
US08512965B2	Methods of identifying ligands to sour-taste receptors comprising PKD1L3 and PKDPKD2L1 The present invention relates to sour taste receptors and compositions and methods thereof. In particular, the present invention provides assays and methods of screening for ligands specific for sour taste receptors. Additionally, the present invention provides methods for screening for accessory proteins and mutations, polymorphisms and other potential sour taste receptor protein mutations that are associated with disease states, and therapeutic agents, ligands, and modulators of such proteins. The present invention also provides compositions and methods for modulating sour taste receptors in vitro and in vivo.
US08512963B2	Detection and quantitation of full-length thioredoxin (TRX) and truncated thioredoxin (TRX 80) in complex samples The present invention relates, e.g., to a method for detecting a full-length protein and a truncated form (e.g., a naturally occurring cleavage product) thereof, in a sample, comprising optionally denaturing and reducing proteins in the sample, cleaving the proteins into smaller peptides, and detecting a unique peptide identifier for the full-length protein and/or a unique peptide identifier for the truncated protein, in the sample. In one embodiment of the invention, the full-length protein is thioredoxin (TRX), and the truncated form thereof is its biologically active, C-terminal truncated, 10 kDa cleavage product, TRX 80.
US08512962B2	Kit and method for detecting bovine viral diarrhea virus in tissue samples The present invention relates to the method for treatment of tissue samples with proteolytic/histolytic additive collagenase or other similar protease prior to testing with an antigen capture immunoassay to identify cattle infected with Bovine Viral Diarrhea Virus (BVDV). The use of collagenase or other similar protease in antigen extraction step of the assay drastically increases accuracy of the assay, thus it allows for a more effective, reliable, quick, and cost effective way of identifying and thereby removing infected cattle and/or other animals from an otherwise uninfected herd.
US08512961B2	Methods of detecting and treatment of cancers using Scutellaria barbata extract An extract of Scutellaria Barbata D. Don is effective in the arrest of cancer cell growth. The extract of Scutellaria Barbata D. Don may be used as a therapeutic treatment for patients who have been identified as having cancer. In some situations, a patient is identified as having a type of cancer by detecting the presence of a biomarker for that cancer in the patient's system and by further determining the level of that biomarker in the patient's system. If the level of the biomarker is above a predetermined threshold level for that biomarker, the patient may be diagnosed with cancer. Subsquently, treatment using an extract of Scutellaria Barbata D. Don may begin. Biomarkers of interest in the detection of the presence of metastitic breast cancer include 8-oxoguanine and lactate dehydrogenase.
US08512959B2	Monoclonal antibody based biomarker discovery and development platform A method or platform for monoclonal antibody based biomarker discovery is disclosed. The method according to the invention provides for the integration of analyte collection, hybridoma screening and nanovolume integrated mass spectrometry (NVIMS) to achieve a robust screening system that is capable, for example, of cutting 4-6 years off of the classical biomarker discovery and development process. The invention provides a platform for the rapid, high-throughput production, isolation and characterization of, e.g., disease specific biomarkers together with highly specific monoclonal antibodies. The method of the invention has a variety of applications such as, but not limited to, drug testing, biohazard applications, ecological applications, physiological applications and/or pathology screening applications. The method of the invention is also capable of being performed or used as or with a high-throughput screening process or system of the invention.
US08512956B2	Method for clonal amplification The present method provides methods, libraries, and kits related to the archiving and clonal amplification of sequences related to target polynucleotide sequences. The method allows for the generation and attachment of polynucleotides with defined 3′ and 5′ ends to solid surfaces. The polynucleotides attached to the solid substrates can be stored or archived as libraries and can subsequently be retrieved for analysis, for example by clonal amplification using a single composite amplification primer comprising a DNA portion and an RNA portion. In some embodiments, nucleotides attached to solid surfaces can be used for sequencing of nucleotide sequences related to the target DNA. The methods are applicable to total RNA and/or total DNA analysis.
US08512951B2	Methods for diagnosing stomach cancer using MicroRNAs The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis.
US08512949B2	Diagnosis/treatment option for head-and-neck tumor using micro-RNA as biomarker Disclosed are: a method for using a particular microRNA as a biomarker for head-and-neck tumor; a method for the determination of head-and-neck tumor; a kit for the determination of head-and-neck tumor, and the like. The present invention is characterized in that at least one microRNA selected from the group of microRNAs consisting of miR-455-3p, miR-455-5p, miR-130b, miR-130b*, miR-801, miR-196a, miR-21, miR-31, miR-133b, miR-145 and miR-375 is used as a biomarker for head-and-neck tumor.
US08512940B2	Method for preserving liver in a solution comprising dibutyryl cAMP The present invention provides a liver preservation solution containing trehalose and dibutyryl-cAMP. The content of nitroglycerin in the preservation solution is preferably lower than 0.44 mM. In the liver preservation solution of the present invention, since the toxicity due to nitroglycerin, which is observed during liver preservation, has been improved, liver transplantation can be performed with a high engrafted rate.
US08512938B2	Methods of forming a pattern in a material and methods of forming openings in a material to be patterned Methods of forming a pattern in a material and methods of forming openings in a material to be patterned are disclosed, such as a method that includes exposing first portions of a first material to radiation through at least two apertures of a mask arranged over the first material, shifting the mask so that the at least two apertures overlap a portion of the first portions of the first material, and exposing second portions of the first material to radiation through the at least two apertures. The first portions and the second portions will overlap in such a way that non-exposed portions of the first material are arranged between the first portions and second portions. The non-exposed or exposed portions of the first material may then be removed. The remaining first material may be used as a photoresist mask to form vias in an integrated circuit. The pattern of vias produced have the capability to exceed the current imaging resolution of a single exposure treatment.
US08512935B2	Functionalized perfluoropolyether material as a hydrophobic coating In some embodiments, without limitation, a hydrophobic photoresist material and a method of making the photoresist material are provided. The photoresist material is derived by creating a high resolution insoluble, or more soluble, polymer structure as a result of a controlled chemical reaction with a functionalized perfluoropolyether. Also provided are methods of coating an inkjet printhead surface and processing the coated inkjet printhead surface.
US08512934B2	Sulphonium salt initiators Compounds of the formula (I), wherein X is a single bond, CRaRb O, S, NRC, NCORC, CO, SO or SO2; L, L1, L2, L3, L4, L5, L6, L7 and L8 are for example hydrogen, R1 or COT; T denotes T1 or O-T2; T1 and T2 for example are hydrogen, C1-C20alkyl, C3-C12cycloalkyl, C2-C20alkenyl, C5-C12cycloalkenyl, C6-C14aryl, C3-C12heteroaryl, C1-C20alkyl substituted by one or more D, C2-C20alkyl interrupted by one or more E, C2-C20alkyl substituted by one or more D and interrupted by one or more E or Q; R1, R2, R3, R4, Ra, Rb and Rc are T1; D is for example R5, OR5, SR5 or Q1; E is for example O, S, COO or Q2; R5 and R6 for example are hydrogen, C1-C12alkyl or phenyl; Q is for example C6-C12bicycloalkyl, C6-C12bicycloalkenyl or C6-C12tricycloalkyl; Q1 is for example, C6-C14aryl or C3-C12heteroaryl; Q2 is for example C6-C14arylene or C3-C12heteroarylene; Y is an anion; and M is a cation; provided that at least one of L, L1, L2, L3, L4, L5, L6, L7 and L8 is other than hydrogen; and provided that (i) at least one of T1 or T2 is a group Q; or (ii) at least one D is a group Q1; or (iii) at least one E is a group Q2; are suitable as photolatent catalysts.
US08512928B2	Carrier for developing electrostatic latent image, and two-component developer, supplemental developer, image forming apparatus, process cartridge, and image forming method using the carrier A carrier comprising a magnetic core particle having a shape factor SF-2 of 130 to 160 and a resin layer covering a surface of the magnetic core particle. The resin layer comprises a conductive particle and a resin obtained by heating a copolymer comprising a silicon-containing A unit and another silicon-containing B unit.
US08512922B2	Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus Aspects of the present invention provide an electrophotographic photosensitive member in which an intermediate layer contains metal oxide particles, an organic resin, and a specific compound (fluorenone derivative), and a process cartridge and an electrophotographic apparatus including the electrophotographic photosensitive member.
US08512919B2	Method and system for design of a reticle to be manufactured using variable shaped beam lithography A surface manufactured using variable shaped beam (VSB) shots is disclosed, where either: 1) the left edge of a first VSB shot intersects the top edge of a second VSB shot, and the bottom edge of the first VSB shot intersects the right edge of the second VSB shot; or 2) the left edge of the first VSB shot intersects the bottom edge of a second VSB shot, and the top edge of the first VSB shot intersects the right edge of the second VSB shot; and where neither shot crosses a field boundary of the VSB charged particle beam writer.
US08512911B2	Fuel supply systems having operational resistance A fuel supply (1) including a cover (2) having an opening (8) for access to the fuel. The cover (2) includes a shutter (12) or similar element for closing off the opening (8) to increase the operational resistance to the insertion and/or removal of the fuel supply (1). In one embodiment, the cover (1) includes a support (6) with a rotatable cap (4), where the rotation of the cap causes the shutter (12) to open. In another embodiment, the cover includes a base and a slidable cap, where the slidable cap is the shutter. The shutter (12) may be manually actuated, mechanically actuated or electrically actuated. The cover (2) may be biased to the open position or to the closed position.
US08512905B2	Catalyst slurry, electrode prepared by using the catalyst slurry, and fuel cell including the electrode A catalyst slurry, an electrode prepared by using the same, and a fuel cell including the electrode. The catalyst slurry includes: a catalyst material; a binder; and a solvent including a first liquid for dissolving the binder and a second liquid having a viscosity that is higher than that of the first liquid.
US08512903B2	Polymer electrolyte fuel cell and method for measuring voltages of cells in polymer electrolyte fuel cell A polymer electrolyte fuel cell of the present invention includes: plate-shaped cells (10) each having a pair of plate-shaped separators (6a) and (6b) and a membrane-electrode assembly (5) disposed between the separators (6a) and (6b); a cell stack (50) configured by stacking and fastening the cells (10); and a covering member (60) covering a peripheral surface of the cell stack (50), and voltage measuring terminal insertion holes (61) used to measure the voltages of the cells (10) are formed on the covering member (60) so as to be located at positions corresponding to the separators (6a) and (6b) of the cells (10).
US08512902B2	System and method of purging fuel cell stacks A fuel cell stack comprising a fuel inlet and an oxidant inlet for allowing the supply of a fuel and an oxidant to the fuel cell stack, respectively, and a fuel outlet and an oxidant outlet for allowing the removal of an anode exhaust and a cathode exhaust from the fuel cell stack, respectively, wherein the fuel outlet is fluidly connected to a high frequency purge valve.
US08512901B2	High-temperature fuel cell system The invention relates to a high-temperature fuel cell system which can be operated with at least one hydrocarbon compound, preferably with methane or a gas containing methane such as natural gas or biogas. It is the object of the invention to increase the efficiency of high-temperature fuel cell systems and to allow a more flexible operation. In the system in accordance with the invention, individual fuel cells are present which are connected electrically in series and form the stacks. The stacks are flowed through after one another by fuel gas which contains hydrogen and which flows into a first stack of the system from a reformer and a suitable hydrocarbon compound is supplied via further connection lines in the flow direction of the introduced fuel gas sequentially into further stacks to the respective stack for a direct internal reforming of a hydrocarbon compound at anodes of the fuel cells of the stack and air is supplied as an oxidation means at the cathode side to the individual fuel cells of the system.
US08512900B2	Nonaqueous electrolytic solution secondary battery A nonaqueous electrolytic solution secondary battery includes a positive electrode, a negative electrode, and a nonaqueous electrolytic solution having an electrolyte salt dissolved in a nonaqueous solvent. The nonaqueous solvent contains 80% by mass or more of a cyclic carbonate which does not have a carbon-carbon multiple bond and which does not contain a halogen and contains a cyclic sulfone compound having any one of structures represented by the following formulae (1) to (4): wherein each of R1 and R2 represents CmH2m where 1≦m≦4. Also, each of R3 to R10 independently represents CnH2n+1 where 1≦n≦4.
US08512899B2	Polymers obtained from monomers allowing a sequential polymerization, and their use for preparing ionic conductors The present invention concerns polymers obtained by anionic initiation and bearing functions that can be activated by cationic initiations that are not reactive in the presence of anionic polymerization initiators. The presence of such cationic initiation functions allow an efficient cross-linking of the polymer after molding, particularly in the form of a thin film. It is thus possible to obtain polymers with well-defined properties in terms of molecular weight and cross-linking density. The polymers of the present invention are capable of dissolving ionic compounds inducing a conductivity for the preparation of solid electrolytes.
US08512888B2	Current collector and method for producing the same, battery and method for producing the same The present invention provides a current collector, a battery including the current collector, which are capable of increasing energy density or output density and improving productivity or stability; it also provides a method for producing the current collector and a method for producing the battery. The current collector comprises: an insulating substrate; and electron-conducting portions respectively disposed on one face and the other face of the insulating substrate, at least two of the electron-conducting portions being disposed in a planar direction on the one face of the insulating substrate, the electron-conducting portions which is disposed on the other face of the insulating substrate being disposed in a manner to face at least one of the electron-conducting portions disposed on the one face of the insulating substrate so that the insulating substrate is interposed therebetween, and the electron-conducting portions disposed on the one face of the insulating substrate and the electron-conducting portions disposed on the other face of the insulating substrate, both of which face each other with the insulating substrate interposed therebetween, are connected to each other via electron conductors disposed in holes penetrating the insulating substrate.
US08512887B2	Pressure relief mechanism for an energy storage system An energy storage system comprising at least one energy storage module implemented as a sealed or submersible unit and adapted to supply electrical energy to a hybrid vehicle. The energy storage module comprises an enclosure and at least one battery array located within the enclosure. The energy storage module includes a pressure relief panel held in place by springs that allows battery gases to escape if gas pressures reach a predetermined threshold. Pressure in the enclosure compresses the springs causing the pressure relief panel to temporarily move outward until pressure is relieved at which time the springs force the pressure relief panel to reseal the enclosure.
US08512883B2	Double silver low-emissivity and solar control coatings A low-emissivity multilayer coating includes, in order outward from the substrate, a first layer including a layer containing titanium oxide, a layer containing silicon nitride, or a sublayer layer containing titanium oxide in combination with a sublayer containing silicon 5 nitride, a second layer including Ag, a third layer including at least one layer selected from titanium oxide layers and silicon nitride layers, a fourth layer including Ag, and a fifth layer including silicon nitride, where the color of the coatings can be varied over a wide range by controlling the thicknesses of the layers of titanium oxide, silicon nitride and Ag.
US08512881B2	Organic material and organic light emitting device including the same Disclosed are an organic material including a compound represented by the following Chemical Formula 1, and an organic light emitting device including the organic material. In Chemical Formula 1, A is an oxygen (O) atom or a sulfur (S) atom, M is a divalent or trivalent metal atom, R1 is an organic group, Y is a substituted or unsubstituted condensed polycyclic aromatic group, Z1 to Z4 are independently a carbon atom or a nitrogen atom, m is an integer ranging from 1 to 4, and n is 2 or 3.
US08512880B2	Organometallic complex, and light-emitting element and light-emitting device using the organometallic complex A material which can emit phosphorescence is disclosed. Further, a light-emitting element having good chromaticity is disclosed. An embodiment of the present invention is an organometallic complex including a structure as represented by the general formula (1): wherein R1 represents an alkyl group having 1 to 4 carbon atoms; each of R2 to R5 represents any one of hydrogen, a halogen element, an acyl group, an alkyl group, an alkoxyl group, an aryl group, a cyano group, and a heterocyclic group; Ar represents an aryl group or a heterocyclic group, preferably, an aryl group having an electron withdrawing group or a heterocyclic group having an electron withdrawing group; and M represents a Group 9 element or a Group 10 element. By virtue that the Ar has an electron withdrawing group, an organometallic complex which emits phosphorescence with higher emission intensity can be obtained.
US08512873B2	Surface treated copper foil and copper clad laminate To provide a surface treated copper foil satisfying all of the bonding strength to polyimide film, chemical resistance, and etching property, and to provide a CCL using the surface treated copper foil, a surface treated copper foil is formed being comprising an untreated copper foil on at least one surface of which Ni—Zn alloy is deposited, wherein Zn content (wt %)=Zn deposition amount/(Ni deposition amount+Zn deposition amount)×100 is 6% or more and 15% or less, and Zn deposition amount is 0.08 mg/dm2 or more, or, a CCL is formed being comprising a surface treated copper foil and a polyimide film laminated on the surface treated copper foil, wherein the surface treated copper foil comprises an untreated copper foil on at least one surface of which Ni—Zn alloy is deposited, Zn content (wt %)=Zn deposition amount/(Ni deposition amount+Zn deposition amount)×100 is 6% or more and 15% or less, and Zn deposition amount is 0.08 mg/dm2 or more.
US08512869B2	Silicon composition and organic light emitting device including the same A silicon composition with a silicon compound represented by Formula 1 and a silicon compound represented by Formula 2: wherein, R1, R2, R3, R4, R11, R12, R13, R14, R15, R16, R17, R18, and R19 are each independently a C1-C4 alkyl group, R5, R6, R7, R8, R9, and R10 are each independently hydrogen or deuterium, k, m, and n are positive integers, and the ratio of k to the sum of m and n is from about 1:0.001 to about 1:0.2; and an organic light emitting device including the same.
US08512863B2	Aqueous dispersions of hybrid coacervates delivering specific properties onto solid surfaces and comprising inorganic solid particles and a copolymer The present invention is directed to a process for the preparation of an aqueous dispersion of coacervates having a core-shell structure, the core (a) being an inorganic particle being anionic or cationic and the shell (b) being a copolymer wherein said copolymer comprises at least two parts, A and B, part A being cationic if particle (a) is anionic, and anionic if particle (a) is cationic, and part B being neutral in pH conditions of said dispersion. More particularly, the invention is directed to treating compositions comprising that aqueous dispersion of coacervates delivering antifouling, water sheeting, antisoiling, anti-adhesion, adhesion, anti-deposition, and/or anti-UV properties onto all kinds of surfaces.
US08512862B2	Polyvinyl formamide (PNVF) and polyvinyl amine (PVAm)nanoparticles, nanocapsules and nanogels Acid-labile poly(N-vinyl formamide) (“PNVF”) nanocapsules were synthesized by free radical polymerization of N-vinyl formamide with optional active ingredients on the surface of silica nanoparticles. Polymerization in the presence of a novel cross-linker that contains an acid-labile ketal facilitated stable etching of silica nanoparticle templates using sodium hydroxide and recovery of PNVF nanocapsules. The formamido side group of PNVF was then hydrolyzed by extended exposure to sodium hydroxide to produce polyvinylamine (“PVAm”) nanocapsules. PNVF and PVAm nanoparticles are also synthesized that form nanogels with optional active ingredients.
US08512861B2	Multi-layer three-dimensional structures having features smaller than a minimum feature size associated with the formation of individual layers Embodiments of multi-layer three-dimensional structures and formation methods provide structures with effective feature (e.g. opening) sizes (e.g. virtual gaps) that are smaller than a minimum feature size (MFS) that exists on each layer as a result of the formation method used in forming the structures. In some embodiments, multi-layer structures include a first element (e.g. first patterned layer with a gap) and a second element (e.g. second patterned layer with a gap) positioned adjacent the first element to define a third element (e.g. a net gap or opening resulting from the combined gaps of the first and second elements) where the first and second elements have features that are sized at least as large as the minimum feature size and the third element, at least in part, has dimensions or defines dimensions smaller than the minimum feature size.
US08512860B2	Housing and method for making the same A housing is provided which includes an aluminum or aluminum alloy substrate, an aluminum layer and a corrosion resistant layer formed on the aluminum or aluminum alloy substrate in that order. The corrosion resistant layer is an Al—O—N layer. Then, Nd ions is implanted in the Al—O—N layer by ion implantation process. The atomic percentages of N and O in the Al—O—N gradient layer gradually increase from nearing the aluminum or aluminum alloy substrate to far away from it. The housing has a higher corrosion resistant. A method for making the housing is also provided.
US08512856B2	Method for producing wiring board and wiring board The present invention provides a wiring board giving good heat dissipation over a long period of use. The present invention also provides a method for producing a wiring board, including coating a surface of a metal substrate, which is made of an aluminum plate, with a composition containing a substance having a polysiloxane structure and inorganic particles having insulating and heat-dissipating properties, curing the composition, then bonding a copper foil to the cured composition, and partially removing the copper foil, thereby forming a wiring layer.
US08512855B2	Self-cleaning member and coating composition A self-cleaning member comprising a member having a porous surface is disclosed. The member has a contact angle hysteresis Δθ (=θa−θr), which is a difference between an advancing contact angle θa and a receding contact angle θr measured by a dynamic contact angle measurement with an extension/contraction method, of 80 degree or more at the surface layer and a receding contact angle θr of 25 degree or less, is capable of forming a water film on the surface by water provided and of allowing an ionic or reactive contaminant to be washed away without fixation.
US08512853B2	Composite structure having reinforced core A polymer-based composite sandwich includes a core bonded between fiber reinforced resin facesheets. The core includes a truss formed by groups of composite pins held in a low density foam. The pins in each group intersect to form nodes adjacent to one of the facesheets. The ends of the pins extend parallel and are bonded to the facesheets.
US08512849B2	Corrugated interfaces for multilayered interconnects Dielectric composite structures comprising interfaces possessing nanometer scale corrugated interfaces in interconnect stack provide enhances adhesion strength and interfacial fracture toughness. Composite structures further comprising corrugated adhesion promoter layers to further increase intrinsic interfacial adhesion are also described. Methods to form the nanometer scale corrugated interfaces for enabling these structures using self assembling polymer systems and pattern transfer process are also described.
US08512847B2	Transparent conductive laminate and touch panel This invention aims to provide a transparent conductive laminate excellent in sliding durability, edge-writing durability, finger writing durability and light resistance and suitable as a movable electrode substrate for a touch panel. Further, it aims to provide a touch panel using the above transparent conductive laminate. This invention is a transparent conductive laminate that is a laminate formed by laminating a polymer film, a cured resin layer-1 and a transparent conductive layer in this order, the cured resin layer-1 having concavoconvex shapes formed by phase separation of two components and containing no fine particles that impart concavoconvex shapes, and the cured resin layer-1 having an arithmetic average roughness (Ra), measured according to JIS B0601-1994, of 0.05 μm or more but less than 0.5 μm and a ten-point average roughness (Rz), measured according to JIS B0601-1982, of 0.5 μm or more but less than 2.0 μm, and a touch panel using the transparent conductive laminate.
US08512846B2	Two-dimensional arrays of holes with sub-lithographic diameters formed by block copolymer self-assembly Methods for fabricating sublithographic, nanoscale microstructures in two-dimensional square and rectangular arrays utilizing self-assembling block copolymers, and films and devices formed from these methods are provided.
US08512845B2	Molded male surface fastener A molded male surface fastener includes resin invasion preventing walls, which prevent an invasion of a molding foamable resin material of a cushion body, on right and left edge portions along a longitudinal direction of a surface of a flat base member made of a thermoplastic resin, a plurality of engaging elements provided between left and right resin invasion preventing walls, and a linear sealing body that is continuously disposed in the longitudinal direction of the base member along a peripheral portion of a top portion of each resin invasion preventing wall. When an engaging element forming surface of the surface fastener is placed on a concavo-convex surface of foaming body molding cavities of a foaming mold, if the mold has the same magnetic force as that in the related art, the linear sealing body is well adhered along the concavo-convex surface.
US08512843B2	Composite matrix and gel padding and method of manufacturing Composite and laminated composite padding materials or cushions formed from an elastic foam matrix structurally supporting and encapsulated gel elements are disclosed. Methods of manufacturing such composite and laminated composite padding materials or cushions are also disclosed.
US08512831B2	Laminate and, paper container and package using the same The present invention relates to a laminate which has oxygen barrier property and flavor barrier property and which is excellent in sealing property and anti-delamination property, and to a paper container and a package utilizing the laminate and suitable for long term storage of contents and excellent in disposability.The laminate is characterized in that the same comprises a multi resin layer including at least three layers comprising adhesive resin layer (a)/barrier resin layer (b)/adhesive resin layer (a′) coextrusion laminated onto a base paper coated with polyethylene imine such that the adhesive resin layer (a) is contacted with the coated surface of the base paper, thereby enhancing an adhesion strength between the coextrusion laminated resin layer and the base paper, with lower odor and excellent barrier property.
US08512828B2	Biaxially oriented white polypropylene film, reflection plate and receiving sheet for thermal transfer recording A biaxially oriented white polypropylene film containing a core layer (layer A) and a skin layer (layer B), said layer B is laminated at least on one surface of said layer A, wherein said layer A contains a polypropylene resin having β-crystal activity and 1 to 20 mass % particle (a) having an average dispersed diameter of 60 to 400 nm, and wherein, said layer B contains a polypropylene resin and 0.05 to 5 mass % particle (b) of an average dispersed diameter of 1 to 4 μm. The present invention provides a biaxially oriented white polypropylene film excellent in film quality and productivity and capable of making sensitivity and productivity compatible in a high level when used as a base for a receiving sheet, and a receiving sheet for thermal transfer recording made thereof.
US08512827B2	Ink jet recording medium Provided is an ink jet recording medium which is capable of reproducing a wide range of gloss including high luster like metallic luster and substantially no luster due to matting by varying only the amount of applied ink and in which the consumption of a white ink used to adjust the glossiness thereof is small.
US08512822B2	Retardation film, method for manufacturing the same, and liquid crystal display device including the same The present invention relates to a retardation film, a method for manufacturing the same, and a liquid crystal display device including the same. More particularly, the present invention relates to a retardation film that includes 1) an acryl-based film, and 2) a coating layer of a negative C type material, the retardation film according to the exemplary embodiment of the present invention may be applied to an IPS (in-plane switching) mode liquid crystal display, and it is possible to control a ratio of an in-plane retardation value and a thickness retardation value of the retardation film.
US08512819B2	Liquid crystal display device Provided is a liquid crystal display device includes: a first substrate (6); a second substrate (7); a liquid crystal layer (LC); a first alignment film (606) placed on the first substrate; a second alignment film (705) placed on the second substrate; and at least one of: a transparent layer (610) contacting the first alignment film on the other side of the liquid crystal layer and being lower in volume resistivity than the first alignment film; and a transparent layer (710) contacting the second alignment film on the other side of the liquid crystal layer and being lower in volume resistivity than the second alignment film, wherein the transparent layer contains polysiloxane expressed by Chemical Formula 1: where R1 and R2 each represent an alkyl group or alkoxy group having 1 to 3 carbon atoms, or a hydroxyl group, and at least 30% of hydroxyl groups are contained.
US08512817B2	Lithographic apparatus and a method of forming a lyophobic coating on a surface A method of forming a lyophobic coating on a surface having oxidized groups is disclosed. The method includes bringing into contact with the surface a silane or siloxane having the formula SiX4 wherein each X is the same or different, wherein at least one X is a leaving group and at least one X is a lyophobic group.
US08512816B2	Method of fabricating thin film by microplasma processing and apparatus for same Provided is a method of fabricating, with satisfactory adhesion, a thin film of a metal or a metallic-compound, such as a metal oxide or nitride, on a substrate made of a high-melting-point material such as silicon or ceramics by using a metal or metallic-compound target as the primary raw material so as to eliminate the necessity of using harmful gases such as organometallic gas, and by using an atmospheric-pressure plasma generated under atmospheric pressure as a reaction field and also as a heat source. Additionally provided is an apparatus for fabricating the thin film. The thin-film fabrication method by microplasma processing includes the steps of disposing a raw material for thin-film fabrication in one or more tubes (A) having a uniform inner diameter throughout, introducing an inert gas and applying a high-frequency voltage to the narrow tubes (A) to generate high-frequency plasma in the narrow tubes (A), heating/evaporating the raw material while maintaining the flow rate of the plasma gas in the narrow tubes (A) and maintaining the plasma gas temperature high, ejecting the evaporated material from the narrow tubes (A) to spray it onto the substrate, heating the substrate with the plasma, and depositing the sprayed material on the substrate under atmospheric pressure.
US08512815B2	Process for wood acetylation and product thereof A process for the acetylation of wood comprising submerging the wood in an acetylation fluid under pressure, and subsequently heating the wood under controlled conditions to initiate two distinct exothermic reactions. The process permits the simultaneous upgrading of large quantities of commercial wood sizes having a natural durability class 4 or class 5 to a unique product of durability class 1 or class 2.
US08512813B2	Coating composition, coating film made of same, and optical article There is provided a coating composition having a good wetting property which is capable of forming a coating film exhibiting a high refractive index, a less discoloration, and excellent transparency and uniformity when polymerized and cured. The present invention relates to a coating composition comprising (A) 100 parts by weight of a thiirane ring-containing compound, (B) 0.0001 to 10 parts by weight of a catalyst for accelerating polymerization of the thiirane ring-containing compound, and (C) 0.005 to 4 parts by weight of a modified silicone oil; a coating film produced from the composition; and an optical product provided with the coating film.
US08512812B2	Aqueous dispersion containing a complex of poly(3,4-dialkoxythiophene) and a polyanion and method for producing the same An aqueous dispersion used for producing a conductive film is provided. The dispersion contains a complex of poly(3,4-dialkoxythiophene) and a polyanion, and is produced by polymerizing 3,4-dialkoxythiophene in an aqueous solvent in the presence of the polyanion by using peroxodisulfuric acid as an oxidizing agent or by using an oxidizing agent and an acid that is employed so as to lower pH of the reaction mixture.
US08512809B2	Method of processing multilayer film A method of processing a multilayer film is provided. The method includes providing a substrate film having a substrate film first surface and a substrate film second surface. The method also includes providing a barrier layer adjacent to the substrate film second surface. The barrier layer has at least one opening allowing fluid communication between the substrate film and an outer surface of the barrier layer. Further, the method includes contacting the substrate film first surface with a first reactant and finally contacting the outer surface of the barrier layer with a second reactant, said second reactant being reactive with said first reactant. The method of contacting the substrate film first surface to the first reactant and contacting the outer surface of the barrier layer to the second reactant is carried out under conditions under which reaction between said first reactant and the second reactant results in a formation of a reaction layer.
US08512806B2	Large volume evaporation source A containment vessel for evaporating materials for use in applying film coatings to a substrate includes a body fabricated from a refractory material. In one embodiment the body includes end portions capable of being connected to other bodies in an end to end fashion. In another embodiment, the body includes an integral patterned conductor incorporated into the outer surface portion of the body to facilitate association with an electrical power source for heating.
US08512804B2	Method and apparatus for finishing a wood panel A method for finishing an engineered wood board. The method includes: cleaning the top and bottom, applying a first top resin layer, which contains corundum particles, to the top and a first bottom resin layer to the bottom, drying the first top and first bottom resin layers to a residual moisture content of 3% to 6%, applying a second top resin layer, which contains cellulose, to the top and a second bottom resin layer to the bottom, drying the second top and second bottom resin layers to a residual moisture content of 3% to 6%, applying an at least third top resin layer, which contains glass particles, to the top and an at least third bottom resin layer to the bottom, drying the third top and third bottom resin layers to a residual moisture content of 3% to 6%, and pressing the multilayer structure under pressure and heat.
US08512799B2	Process of producing a superconducting magnet made of a high-temperature bulk superconductor There is established a superconducting magnet made of a high-temperature bulk superconductor and capable of trapping a high magnetic field with ease and stably. The superconducting magnet made of the high-temperature bulk superconductor, for use by trapping a magnetic field, is made of the bulk superconductor with an artificial hole therein, a low-melting metal impregnated into, and filling up at least the artificial hole, and a heat-conducting metal material embedded in portions of the high-temperature bulk superconductor, impregnated with, and filled with the low-melting metal. The superconducting magnet can be produced by a process involving the steps of providing the artificial hole in the high-temperature bulk superconductor, disposing the heat-conducting metal material in at least the artificial hole, applying a process of impregnating and filling up at least the artificial hole with the low-melting metal, and subsequently, executing a process of magnetizing.
US08512796B2	Vessel inspection apparatus and methods Methods for processing a vessel, for example to provide a gas barrier or lubricity, are disclosed. First and second PECVD or other vessel processing stations or devices and a vessel holder comprising a vessel port are provided. An opening of the vessel can be seated on the vessel port. The interior surface of the seated vessel can be processed via the vessel port by the first and second processing stations or devices. Vessel barrier, lubricity and hydrophobic coatings and coated vessels, for example syringes and medical sample collection tubes are disclosed. A vessel processing system and vessel inspection apparatus and methods are also disclosed, for example using material outgassed from a surface to inspect the properties of a surface coating.
US08512794B2	Oleate ester phytosterol compositions An edible composition for ingestion by mammals, especially by humans, that includes a fat-based blend containing: (a) at least one triglyceride-based fat, (b) a low level of diglycerides, for example, less than 3% by weight of diglycerides, e.g., diacylglycerol (DAG), and (c) at least 2% and in some instances at least 5% by weight of a mixture of fatty acid Ester Phytosterols (EPs), in which at least 65% by weight of the fatty acid EPs are Monounsaturated (oleate)-Ester Phytosterols (MEPs), and less than 20% by weight of the fatty acid EPs are Polyunsaturated (linoleate+alpha-linolenate)-Ester Phytosterols (PEPs). The increased proportion of MEPs and decreased proportions PEPs and diglycerides substantially increase the oxidative stability index (OSI), shelf life, and health benefits of the above mixture of fatty acid EPs, while providing an advantageous melting temperature and desirable mouth feel for this mixture of fatty acid EPs.
US08512792B2	Method and apparatus for producing blocks of cheese A method for producing blocks of cheese from curd, wherein a curd mass is deposited in at least one cheese mold provided with a follower and in the at least one cheese mold is subjected to a vacuum treatment and pressing treatment, which pressing treatment is carried out while the at least one cheese mold is situated in a holder in which a vacuum prevails, wherein the vacuum treatment comprises at least a first and a second step, wherein in the first step in the holder with the aid of vacuum pump means a vacuum with a first vacuum pressure is created to draw air and whey entrained with the air from the curd mass, and in the second step the vacuum pressure in the holder is reduced further to a second vacuum pressure, which has a value at which the whey present in the curd mass starts to boil and residual air and free whey are pushed from the curd mass.
US08512780B2	System and methods for transporting or storing oxidatively-degradable foodstuff Disclosed are packaging systems and methods useful in extending the storage-life of foodstuff such as fresh fish. The packaging systems and methods can be used to transport or store the foodstuff for an extended period of time. The packaging systems preferably use a fuel cell to maintain a reduced oxygen level in the environment surrounding the foodstuff.
US08512779B2	Process for coating food products A process for coating food products, characterized in that the products are coated before they are cooked with an aqueous coating composition including a modified legume starch having an amylose content of less than 40%.
US08512776B2	Capsule with sealing means and its use in a beverage producing system A capsule (1) contains beverage ingredients such as ground coffee, tea or other ingredients and is configured for insertion in a beverage production device (2) in order to have a liquid under pressure have enter the capsule (1) and to interact with the ingredients (3) in the capsule (11). The capsule (1) has a base body (4) and a foil member (5) closing the base body (4) by being attached to a flange-like rim (6) extending from the side wall (7) of the base body (4) of the capsule (1). The base body (4) of the capsule (1) comprises a resilient sealing member (8), the sealing member (8) being designed to be in sealing engagement with a bell member (9) of the beverage production device (2).
US08512775B2	Method for preparing a dairy product A method for preparing a dairy product in a production line, includes a step of continuously injecting at least one sterol and/or stanol ester through the production line at a predetermined temperature T1 no lower than the melting point of the ester, and particularly at a temperature of 35-80° C., and into a dairy composition at a predetermined temperature T2 no lower than the temperature T1, which composition consists of an initial emulsifier-free milk-based composition containing milk proteins, to give a mixture, wherein the step of injecting at least one sterol and/or stanol ester is carried out before a step of homogenizing the mixture.
US08512774B2	Fermentation processes The present invention provides a method for the production of at least one of a fermentation product and a derivate thereof comprising the steps of: a. providing a fermentable aqueous solution comprising at least one fermentable compound and at least one impurity; b. selectively extracting the at least one impurity from at least a portion of the fermentable aqueous solution by means of an extractant to form an impurity-depleted fermentable solution comprising a fermentable compound and to form an impurity-comprising extract; and c. fermenting the fermentable compound of the impurity-depleted fermentable solution to form a fermentation broth comprising a fermentation product wherein the extractant comprises at least one of the fermentation product and a derivate thereof.
US08512769B2	Valerian extract preparation Process for preparing a valerian extract formulation comprising the steps of: a) extracting radix valeriana officinalis with alcoholic-aqueous extractants to obtain a raw extract, said alcoholic-aqueous extractant containing from 10 to 50% by volume of alcohol; b) at least partially removing the alcoholic fraction from the raw extract to obtain a viscous extract; c) contacting the viscous extract with a hydrophobic adsorbing agent; d) separating the hydrophobic adsorbing agent to obtain a purified extract; e) converting the purified extract to a valerian extract formulation using pharmaceutically acceptable auxiliary agents.
US08512768B2	Pain relieving composition A pain relieving composition that includes an anesthetic in the range of 0.5%-7.0% by weight (“w/w”), an anti-inflammatory agent in the range of 1.0%-11.0% w/w, a moisturizing agent in the range of 0.5%-12.0% w/w, a humectant in the range of 0.5%-13.0% w/w, a penetration enhancing agent in the range of 0.5%-7.0%, and a carrier solvent in the range of 40.0%-97.0% w/w to be used before and/or after procedures which cause damage to human skin.
US08512766B2	Plant essential oil-based antimicrobial fish filming compositions and methods of use Novel plant essential oil-based antimicrobial filming compositions that are useful in protecting, repairing and strengthening the natural slime coat found on fish are disclosed, which compositions are comprised of a mixture of plant essential oils having antimicrobial properties, filming agents, and surfactants.
US08512765B2	Plant derived seed extract rich in essentially fatty acids derived from Salvia hispanica L. seed: composition of matter, manufacturing process and use A Salvia hispanica L. derived seed oil extract composition of matter containing from 60-88% PUFAs in a ratio of from 3.1:1-3.3:1 of ALA to LA, 4-10% of C-18 mono-unsaturated fatty acid, 1-5% of C-18 saturated fatty acid and 4-8% of C-16 saturated fatty acid in a mixed triglyceride form stable at room temperature of 12-24 months containing a mixture of selected antioxidants.
US08512763B2	Combinations of 4 bromo 2-(4-chlorophenyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile and metal compounds The present invention relates to combinations of 4-bromo-2-(4-chloro-phenyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile, or a salt thereof, and copper or zinc compounds which provide an improved protecting effect against fouling organisms. More particularly, the present invention relates to compositions comprising a combination of 4-bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile, or a salt thereof, together with one or more copper or zinc compounds selected from Cu2O, Cu(OH)2, CuSO4, copper pyrithione, CuSCN, CuCO3, ZnO, ZnCl2, ZnSO4, zineb, and zinc pyrithione; in respective proportions to provide a synergistic effect against fouling organisms and the use of these compositions for protecting materials against fouling organisms. This invention thus relates to the field of protection of materials, such as underwater objects, protection of wood, wood products, biodegradable materials and coatings.
US08512761B2	Fast acting inhibitor of gastric acid secretion The present invention relates to the use of pharmaceutically acceptable zinc salts, in particular, zinc chloride and zinc acetate alone or optionally, in combination with one or more of a protein pump inhibitor (PPI), H2-blocker, cytoprotective agent or a combination of agents as otherwise described herein for providing fast action with optional long duration effect in reducing gastric acid secretion, including acid secretion in the fundus (by inhibiting vacuolar H+-ATPase or H+/K+-ATPase) and upper body region of the stomach (by inhibiting H+/K+-ATPase), thus raising the pH of gastric juices in rapid fashion and decreasing the duration of stomach acid release during a secretagogue phase. The method is also directed to treating conditions including gastroesophogeal reflux disease, non-erosive reflux disease, Zollinger-Ellison syndrome, ulcer disease, and gastric cancer, as well as preventing or reducing the likelihood of ulcer disease. In addition, the present methods are useful for treating patients who are non-responsive to PPIs and as an alternative to traditional therapies or conditions which are caused by rapid and complete inhibition of secretagogue induced acid secretion.
US08512756B2	Collagen preparation and method of isolation Collagen compositions, methods for preparing those collagen compositions, and graft compositions formed from those collagen compositions are provided. In particular, methods of isolating collagen that exhibits an enhanced rate of polymerization and enhanced microstructural and mechanical properties upon polymerization, such collagen compositions, and graft compositions formed from such collagen compositions are provided.
US08512755B2	Compact multifunctional ligand to enhance colloidal stability of nanoparticles A ligand design allows compact nanoparticle materials, such as quantum dots (QDs), with excellent colloidal stability over a wide range of pH and under high salt concentrations. Self-assembled biomolecular conjugates with QDs can be obtained which are stable in biological environments. Energy transfer with these ligands is maximized by minimizing distances between QDs/nanoparticles and donors/acceptors directly attached to the ligands or assembled on their surfaces.
US08512754B2	Stabilized products, processes and devices for preparing the same A composition comprising a glassified, stabilized particle preparation having a low water activity (between about 0.1 and 0.9) is provided. The preparations provide improved products with enhanced storage stability, less expensive cost of processing, and extended shelf life. The glassified, stabilized particle preparations are particularly efficacious in the preparation of perishable products, especially pharmaceutical agents, such as human blood and blood products (e.g., red blood cells). A single emulsion process comprising a 2-phase system for preserving food and pharmaceutical products is also provided. Stabilized biological products as glassified beads are also provided, as well as a method for rehydrating and/or reconstituting the glassified beads to provide useful and fully active reconstituted and/or rehydrated materials is also presented.
US08512753B2	Micronized particles of low-dosage strength active agents for powder formulations for inhalation Micronized particles of a low-dosage strength active ingredient, to be used in dry powder formulations for inhalation, with particular properties can easily and homogenously disperse in a dry powder formulation to be administered by means of a dry powder inhaler device.
US08512751B2	Pharmaceutical compositions for sleep disorders Pharmaceutical compositions are provided for the pharmacological treatment of breathing disorders and, more specifically, to compositions containing agents having serotonin receptor modulating activity for the alleviation of sleep apnea (central and obstructive) and other sleep-related breathing disorders wherein the active ingredients are released such as to extend effective blood plasma concentrations across the period of sleep.
US08512747B2	Pharmaceutical composition for the treatment of acute disorders A pharmaceutical composition for the treatment of acute disorders is described. The composition comprises an essentially water-free, ordered mixture of at least one pharmaceutically active agent in the form of microparticles which are adhered to the surfaces of carrier particles which are substantially larger than the particles of the active agent or agents, and are essentially water-soluble, in combination with the bioadhesion and/or mucoadhesion promoting agent. The invention also relates to a method for preparing the composition and to the use of the composition for the treatment of acute disorders.
US08512745B2	Ulipristal acetate tablets The invention relates to a pharmaceutical tablet for oral administration comprising ulipristal acetate together with the following excipients: a diluent in an amount of 60 to 95 wt %, a binding agent in an amount of 1 to 10 wt %, croscarmellose sodium in an amount of 1 to 10 wt %, and magnesium stearate in an amount of 0 to 5 wt %.
US08512742B2	Transdermal preparation Provided is a transdermal preparation, which is capable of long-term (1-day to 7-day) release of a basic drug from a preparation, continuously and at a consistent concentration; shows little reduction over time in the drug content, even if multiple drugs are contained in the preparation; and is produced by a simple process. The transdermal preparation comprises a substrate, and an adhesive layer containing a basic drug and a water-soluble polymer.
US08512737B1	Embolic delivery of therapeutic agents This application is directed to means for embolic delivery of therapeutic agents to an afflicted organ in the body of a patient.
US08512736B2	Coatings including natural biodegradable polysaccharides and uses thereof Biodegradable coatings and articles that include natural biodegradable polysaccharides are described. The coatings and articles are formed from a plurality of natural biodegradable polysaccharides having pendent coupling groups.
US08512734B2	Biocompatible coating of medical devices A coated implantable medical device is described, wherein the coating comprises a coating matrix and particles of one or more molecular sieves, preferably zeolite of zeogrid particles, optionally loaded with one or more bioactive agents. The coating matrix itself can function as a second drug-carrying interface. The coating comprising the molecular sieve material has an excellent biocompatibility and allows suitable drug delivery into the body of an animal, preferably a mammal and most preferably a human.
US08512729B2	Fragmented polymeric compositions and methods for their use Cross-linked hydrogels comprise a variety of biologic and non-biologic polymers, such as proteins, polysaccharides, and synthetic polymers. Such hydrogels preferably have no free aqueous phase and may be applied to target sites in a patient's body by extruding the hydrogel through an orifice at the target site. Alternatively, the hydrogels may be mechanically disrupted and used in implantable articles, such as breast implants. When used in vivo, the compositions are useful for controlled release drug delivery, for inhibiting post-surgical spinal and other tissue adhesions, for filling tissue divots, tissue tracts, body cavities, surgical defects, and the like.
US08512728B2	Method of forming a medical device on biological tissue A method for in situ formation of a medical device on biological tissue includes attaching a plurality of reactive members of a primary specific binding pair to a surface of the biological tissue, and providing a plurality of fibers having attached thereto a plurality of complementary reactive members of the primary specific binding pair, wherein upon contact of the reactive members on the surface of the biological tissue with the complimentary reactive members on the fibers, covalent bonds are formed between the reactive members and the complementary reactive members, thus adhering the fibers to the tissue. The fibers can incorporate functionalities which may cause them to bind to one another.
US08512724B2	Antiseptic compositions The present invention provides antiseptic compositions that contain DMSO or DMA, an alcohol (e.g., isopropanol), and/or an additional antiseptic agent such as iodine. In certain embodiments, the antiseptic compositions may be used for skin disinfection and/or skin antisepsis (e.g., as applied via a swab).
US08512717B2	Compositions for delivery of therapeutics into the eyes and methods for making and using same The present invention provides for compositions for administering a therapeutically effective amount of a therapeutic component. The compositions may include an ophthalmically acceptable carrier component; a therapeutically effective amount of a therapeutic component; and a retention component which may be effective to reduce wettability, induce viscosity, increase muco-adhesion, increase meniscus height on a cornea of an eye and/or increase physical apposition to a cornea of an eye of a composition.
US08512715B2	Apparatus and method for treating a neuromuscular defect A method is provided for treating a neuromuscular defect in a subject. One step of the method includes locating a target nerve. After locating the target nerve, a treatment probe is provided. The treatment probe includes an elongated body member having a proximal end portion and a distal end portion. The distal end portion includes an energy delivery mechanism for stimulating or ablating the target nerve, a monitoring mechanism, and a fluid aspiration/delivery mechanism. Next, the target nerve is verified as an appropriate target for ablation by stimulating and then monitoring the target nerve via the energy delivery mechanism and the monitoring mechanism, respectively. After verifying the target nerve, a tumescent fluid is injected into the tissue surrounding the target nerve. An electric current is then delivered to the energy delivery mechanism to substantially ablate the target nerve.
US08512713B2	Myxoma virus mutants for cancer treatment Myxoma viruses that are deficient in the activity of a Myxoma virus protein selected from the group consisting of M11L, M063, M 136, M-T4 and M-T7 are useful for treating cancer.
US08512711B2	VLP based vaccine delivery system An isolated protein comprising a VP1 amino acid sequence wherein one or more exposed loops within said VP1 has an insertion of an amino acid sequence from a virus protein other than VP1, and encoding nucleic acid, are provided. Typically, the virus protein other than VP1 is derived from an influenza virus and in particular, avian influenza virus. The isolated protein may have an insertion of amino acid sequence from a single protein or a plurality of proteins. Also provided are expression constructs, VLPs, pharmaceutical compositions, vaccines and methods of treatment that may be useful in the prophylactic and/or therapeutic treatment of any disease of viral origin, and in particular, influenza virus.
US08512710B2	Class of therapeutic protein based molecules The present invention provides new compositions and methods for preventing and treating pathogen infection. In particular, the present invention provides compounds having an anchoring domain that anchors the compound to the surface of a target cell, and a therapeutic domain that can act extracellularly to prevent infection of a target cell by a pathogen, such as a virus. The present invention also comprises therapeutic compositions having sialidase activity, including protein-based compounds having sialidase catalytic domains. Compounds of the invention can be used for treating or preventing pathogen infection, and for treating and reducing allergic and inflammatory responses. The invention also provides compositions and methods for enhancing transduction of target cells by recombinant viruses. Such compositions and methods can be used in gene therapy.
US08512708B2	GP96 derived peptides Provided is a gp96-derived peptides or homologs or derivatives thereof, pharmaceutical composition including them, a use thereof for therapy and for the manufacture of a medicament, a method of treating a wide range of conditions, disorders and diseases therewith, nucleotide sequences encoding them, antibodies directed to epitopes thereof and fusion proteins including them.
US08512701B2	Anti-CXCL13 and anti-CXCR5 antibodies for the prevention and treatment of cancer and cancer cell migration Methods for prevention or inhibition of the growth or metastasis of cancer cells in a subject are disclosed. One method comprises the step of administering to the subject a therapeutically effective amount of an antibody to the chemokine CXCL13 and/or the chemokine receptor CXCR5. Another method comprises the step of administering to the subject a therapeutically effective amount of an expression vector that expresses an antibody to the chemokine CXCL13 and/or the chemokine receptor CXCR5.
US08512698B2	Compositions and methods for diagnosing and treating an inflammation An isolated polypeptide is provided. The polypeptide comprising an antigen recognition domain capable of specifically binding a human scavenger receptor, wherein the antigen recognition domain comprises at least three CDR amino acid sequences selected from the group consisting of SEQ ID NO: 11, 15, 19, 23, 27 and 31. Also provided are compositions which comprise the peptide and uses of same.
US08512697B2	Delivery of micro- and nanoparticles with blood platelets The invention is directed to platelets containing micron or nanometer size particles wherein the micron or nanometer sized particles comprises an active agent. The invention is also directed to a pharmaceutical composition comprising a pharmaceutically acceptable carrier and the above platelets. The invention is further directed to methods of delivering the micron or nanometer size particles containing an active agent to a site of interest in a patient.
US08512696B2	Methods of isolating non-senescent cardiac stem cells and uses thereof The invention describes the isolation and methods of use of a non-senescent pool of adult cardiac stem cells. In particular, a subset of adult cardiac stem cells with superior regenerative capacity is disclosed. Such cells were found to have immortal DNA. Compositions comprising the non-senescent stem cells are also described. In addition, the present invention provides methods for repairing aged myocardium or damaged myocardium using the isolated non-senescent adult cardiac stem cells.
US08512691B2	Stable liquid interferon-beta formulations Liquid interferon compositions having a pH between 4.0 and 7.2 are described. The compositions comprise interferon-beta and a stabilizing agent at between about 0.3% and 5% by weight which is an amino acid selected from the group consisting of acidic amino acids, arginine and glycine. If needed, salt is added to provide sufficient ionic strength. The liquid composition has not been previously lyophilized or previously cavitated. The liquid is preferably contained within a vessel having at least one surface in contact with the liquid that is coated with a material inert to adsorption of interferon-beta. A kit for parenteral administration of a liquid interferon formulation and a method for stabilizing liquid interferon compositions are also described.
US08512690B2	Derivatised proline containing peptide compounds as protease inhibitors The present application describes organic compounds that are useful for the treatment, prevention and/or amelioration of human diseases.
US08512684B2	Process for the preparation of inverse latex of acrylamide-based polymers and composition comprising said latex Process for the preparation of a composition including an oil phase, an aqueous phase, at least one emulsifying system of water-in-oil (W/O) type, optionally at least one emulsifying system of oil-in-water (O/W) type, in the form of an inverse latex including from 20% to 70% by weight and preferably from 25% to 50% by weight of a branched or crosslinked polyelectrolyte, characterized in that the polyelectrolyte is a copolymer of 2-acrylamido-2-methylpropanesulfonic acid partially or totally salified with acrylamide and optionally one or more monomers chosen from monomers containing a partially or totally salified weak acid function and/or from neutral monomers other than acrylamide, the production process being characterized in that the preparation of the aqueous phase includes the dissolution in the aqueous medium of solid 2-acrylamido-2-methyl propanesulfonic acid before neutralization. Cosmetic, dermopharmaceutical or pharmaceutical composition including the inverse latex directly obtained by the process.
US08512679B2	Glassy compositions Embodiments disclosed herein relate to thermostable storage of one or more therapeutic agents, including at least one detectable indicator. In an embodiment, the one or more therapeutic agents including at least one detectable indicator are included in at least one glassy substance. Also disclosed are embodiments relating to delivery devices for administration of the thermostable therapeutic agents.
US08512678B2	Non-invasive, in vivo fluorescent imaging of the nervous system in whole living animal A method is disclosed involving detecting the expression of a fluorescent protein of interest in an animal, wherein the animal is a transgenic animal having in its genome nucleic acid encoding said fluorescent protein operably linked to promoter nucleic acid from a protein that is normally expressed in the nervous system of the animal, the method comprising the step of non-invasively detecting fluorescence from said protein when expressed in said animal.
US08512674B1	Preparation of molecular sieve SSZ-23 Disclosed is a method for preparing molecular sieve SSZ-23 using a mixture of an N,N,N-trialkyl adamantammonium cation structure directing agent and an N,N′-dialkyl-1,4-diazabicyclo[2.2.2]octane dication.
US08512672B2	Fabrication method of ZnO nano-particle and fabrication method of ZnO nano-fluid using thereof Provided are a method for preparing zinc oxide (ZnO) nanoparticles and a method for preparing ZnO nanofluid using the same. The method for preparing ZnO nanoparticles includes: a) heating deionized water; b) dissolving zinc (Zn) salt in the deionized water to prepare a precursor solution; c) adding solid alkali salt to the precursor solution to prepare a dispersion of ZnO nanoparticles; and d) separating the ZnO nanoparticles by solid-liquid separation and washing them with deionized water. Highly pure, crystalline ZnO nanoparticles with spherical shape and very narrow particle size distribution of 10 to 50 nm can be prepared quickly and at large scale and low cost using inexpensive materials via a stable low-temperature process, without using a dispersant. The associated low-temperature, normal-pressure process produces few harmful materials and may be easily employed for production of ZnO nanoparticles.
US08512669B2	Graphene production using laser heated crystal growth Implementations and techniques for producing graphene are generally disclosed. A seed crystal may be affixed to a support substrate such that the seed crystal faces substantially downwardly and such that the formed graphene crystal hangs substantially downwardly. Feedstock may be provided adjacent to the seed crystal, and a laser beam may be applied to heat the seed crystal and the feedstock to grow a graphene crystal.
US08512663B2	Pyrolysis reactor materials and methods In one aspect, the invention includes a refractory material for a pyrolysis reactor for pyrolyzing a hydrocarbon feedstock, the refractory material comprising an yttria stabilized zirconia, the refractory material comprising at least 21 wt. % yttria based upon the total weight of the refractory material. In another aspect, this invention includes a method for mitigating carbide corrosion while pyrolyzing a hydrocarbon feedstock at high temperature using a pyrolysis reactor system comprising the steps of: (a) providing a pyrolysis reactor system comprising stabilized zirconia in a heated region of the reactor, the stabilized zirconia including at least 21 wt. % yttria and having porosity of from 5 vol. % to 28 vol. %; (b) heating the heated region to a temperature of at least 1500° C.; and (c) pyrolyzing a hydrocarbon feedstock within the heated region.
US08512661B2	Carbonation calcination reaction process for CO2 capture using a highly regenerable sorbent A process for the efficient capture of CO2 and sulfur from combustion flue gas streams and gasification based fuel gas mixtures using regenerable and recyclable calcium based sorbents. The regeneration of the calcium sorbent is accomplished by hydrating the sorbent at high temperatures of about 600° C. and a pressure higher than 6 bars to lower the parasitic energy consumption.
US08512658B2	Method of depleting nitrous oxide in exhaust gas after-treatment for lean-burn engines The present invention relates to a method for exhaust gas after-treatment for essentially lean-burn internal combustion engines and also a corresponding advantageous exhaust gas after-treatment system. In particular, the present invention relates to reducing the proportion of the greenhouse gas N20 in the total exhaust gas from a corresponding internal combustion system using at least one NOx storage catalyst as exhaust gas purification element. The objective of the invention is to operate the N20 depletion catalyst located downstream of the NOx storage catalyst under lambda=<1 conditions when the N20 formed by the NOx storage catalyst reaches the N20 depletion catalyst.
US08512656B2	Apparatus and process for treatment of haloorganosilicon compounds from offgases Regenerator and process for regenerative thermal oxidation of offgases comprising halooganosilocon compounds in which offgases are heated in the regenerator, fed to an oxidation zone present in the regenerator to oxidize the haloorganosilicon compounds to SiO2 and hydrogen halides which form a flue gas which is then cooled in the generator to a temperature below its acid dew point and is discharged.
US08512646B2	Device for generating sterilizing gas, catalyst cartridge applied to device for generating sterilizing gas and device for processing for sterilization A device for generating a sterilizing gas includes a methanol gas generation device (11) for vaporizing methanol to generate a methanol gas, a tubular part (12) and a catalyst section (13). The tubular section (12) is arranged on top of the methanol gas generation device (11) to provide a flow path for upwardly directing the methanol gas generated by the methanol gas generation device by natural convection. The tubular section also operates to mix the methanol gas with a predetermined proportion of air. The catalyst section (13) is arranged on top of the tubular section (12) for turning the methanol gas mixed with the air at the predetermined proportion in the tubular section (12) into radicals by a catalyzed reaction. The catalyst section (13) is formed by a turn-into-radical reaction catalyst layer (30) obtained on forming a thin metal sheet (35a) to a honeycomb structure.
US08512645B2	Bayonet tube exchanger-reactor allowing operation with pressure differences of the order of 100 bars between the tube side and the shell side The present invention describes an exchanger-reactor for carrying out endothermic reactions, comprising a shell inside which a heat transfer fluid moves, said shell enclosing a plurality of tubes inside which the reactant fluid moves, the tubes being of the bayonet type, and the reactor not having a tube plate. This reactor may operate with a pressure difference between the tube side and the shell side which may be up to 100 bars.
US08512638B2	Microchip and analyzer using the same A microchip having an inlet (14) for collecting a liquid sample; at least one capillary cavity (4) capable of collecting a specific amount of the liquid sample through the inlet (14) by using capillary force; and a holding chamber (5) communicating with the capillary cavity (4) and receiving the sample liquid in the capillary cavity (4) transferred by centrifugal force generated by rotation about an axis. The capillary cavity (4) interconnecting the inlet (14) and the holding chamber (5) has, in one side face of the capillary cavity (4), cavities (15, 16) not generating capillary force and communicating with the atmosphere, and this prevents mixing of air bubbles into the capillary cavity (4).
US08512637B2	Device for cutting a sample carrier A device for receiving a sample carrier is provided. The device includes an opening for receiving part of the sample carrier and a cutter for removing a part of the sample carrier. The cutter is coupled to a lid, which is movable to allow the cutter to make an incision in the sample carrier and, at the same time, to close at least part of the opening left open after receipt of the sample carrier. The disclosure further relates to a system comprising such a device and a method for operating such a device.
US08512625B2	Injection blow molding system with enhanced heat transfer channel configuration An injection blow molding (IBM) system and method for controlling the surface temperature of the parison molds by passing heat transfer fluid through a plurality of fluidly-coupled heat transfer channels. The heat transfer channels can be formed primarily in die sets to which the parison molds are attached. The placement and distribution of the heat transfer channels relative to the parison-forming surfaces helps control the temperatures of the bodies and necks of the parisons being formed, instead of relying on various adjustments by an IBM operator. This system/method reduces the discretion required by the IBM operator and shifts the burden of consistently making high-quality parisons and molded articles onto the designer of the IBM tooling.
US08512623B2	Labeler and a labeling method for labeling plastic containers in the blow mold in a rotary blow molder A labeler for labeling plastic containers in the blow mold as well as to a labeling method for use of the labeler, where due to the fact that the rotating insertion device of the labeler comprises articulated arms having each rotatably supported thereon a gripper, it is possible to remove labels from stationary magazines at a comparatively low relative speed. The articulated arms are able to follow the path of the blow molds during insertion of the labels with high speed. The grippers are rotatably supported which allows an exact radial orientation of the gripper with respect to the axis of rotation of the blow wheel that continues to rotate during insertion of the labels, to thus allow a particularly accurate and reliable labeling.
US08512622B2	Manufacturing method for 3D structure of biomaterials using stereolithography technology and products by the same Disclosed is a manufacturing method for a 3D structure of biomaterials using a stereolithography technology capable of ensuring processability of various biomaterials. The manufacturing method for a 3D structure of biomaterials using a stereolithography technology includes: shaping a 3D sacrificial mold by using the stereolithography device; injecting prepared biomaterials into the sacrificial mold by using a solvent; curing the biomaterials by removing the solvent injected into the sacrificial mold; and acquiring the 3D structure from the cured biomaterials by removing the sacrificial mold.
US08512614B2	Modular molding system A molding system including a component formed in a generally closed loop shape and having a plurality of radially extending teeth. The component includes a plurality of discrete segments coupled together.
US08512609B2	Web-processing machine and method for the control thereof A method for operating a web-processing machine having at least one first driven transport roller (2) that transports a material web (10), at least one second transport roller (4) that transports the material web (10), and at least one treatment unit (8) that treats the web, at least one transport roller (2, 4) comprising a drive device (12, 14), and at least one drive device (12) being controlled by a control device (20), and control of said drive device (12) being accomplished as a function of elongation properties of the material web (10), such that when taking into account the elongation properties of the material web (10), a damping of said elongation properties is also taken into account.
US08512608B2	Injection molding method and injection molding device An injection molding device comprises a mold-clamping device that operates in both of a mold-closing state in which a mold is closed under predetermined pressure and a micro mold-open state in which the mold is held in a state in which the mold is open from the mold-closing state by a predetermined amount, an injection device that molds a molded product by injecting a molding material into the mold set to the mold-closing state or the micro mold-open state and a controller that changes a stop position of the mold in the micro mold-open state in accordance with a change of a mold-closing position when the mold-closing position of the mold in the mold-closing state is changed.
US08512604B2	Photochromic coating exhibiting improved performance and reduced yellowness An acrylate-based optical coating composition containing a blend of monomers, a metal salt, a Hindered Amine Light Stabilizer (HALS), an antioxidant (AO), an initiator and a photochromic dye. The initiator has a range of free radical energy that is below a predetermined level. The cure process is controlled by the catalyst and initiator in combination with the HALS and AO to avoid deleterious reactions that can increase yellowness. The composition is well suited to be applied to a lens and cured in the mold to form a coating with reduced yellowness having high adhesion and abrasion-resistant properties. A photochromic segmented bifocal lens is produced with low photochromic fatigue and favorable % T values.
US08512602B2	ITO powder and method of producing the same, coating material for transparent conductive material, and transparent conductive film ITO particles are provided, which are small in variations of particle diameters and used for an ITO coating material capable of forming a transparent conductive film having high transparency and low haze value. Also, ITO coating material is provided, containing such ITO particles, and a transparent conductive film containing such ITO particles. Further, ITO powders are provided, wherein 90% or more of ITO particles constituting the ITO powders have a primary particle diameter of 20 nm or less.
US08512600B2	Polycarbonate resin composition having excellent wear resistance and electric conductivity and method of preparing the same The present invention provides a polycarbonate resin composition comprising a polycarbonate (A), a styrene copolymer resin (B), carbon nano-tubes (C) and a carbon black (D).
US08512599B2	Carbonitride based phosphors and light emitting devices using the same Disclosed herein is a novel group of carbidonitride phosphors and light emitting devices which utilize these phosphors. In certain embodiments, the present invention is directed to a novel family of carbidonitride-based phosphors expressed as follows: Ca1−xAlx−xySi1−x+xyN2−x−xyCxy:A; (1) Ca1−x−zNazM(III)x−xy−zSi1−x+xy+zN2−x−xyCxy:A; (2) M(II)1−x−zM(I)zM(III)x−xy−zSi1−x+xy+zN2−x−xyCxy:A; (3) M(II)1−x−zM(I)zM(III)x−xy−zSi1−x+xy+zN2−x−xy−2w/3CxyOw−v/2Hv:A; and (4) M(II)1−x−zM(I)zM(III)x−xy−zSi1−x+xy+zN2−x−xy−2w/3−v/3CxyOwHv:A, (4a) wherein 0xy+z, and 0
US08512597B2	Polymerizable optically active imide compound and polymerizable composition containing the compound A polymerizable optically-active imide compound represented by the following general formula (I). Preferable among the polymerizable optically-active imide compound are compounds wherein X3 and X4 in general formula (I) are both —CO—, compounds wherein the rings A2 and A3 in general formula (I) are both naphthalene rings, compounds wherein the rings A1, A2, A3, and A4 are all benzene rings, compounds wherein M1 and M2 in general formula (I) are both hydrogen atoms, or compounds wherein rings A1 and A4, as well as rings A2 and A3, in general formula (I) are the same ring, the groups M1 and M2, X1 and X6, X2 and X5, as well as X3 and X6 are the same group in each pair, and n and m are the same number.
US08512593B2	Chemical mechanical polishing slurry compositions, methods of preparing the same and methods of using the same Provided herein are chemical mechanical polishing (CMP) slurries and methods for producing the same.Embodiments of the invention include CMP slurries that include (a) a metal oxide; (b) a pH-adjusting agent; (c) a fluorinated surfactant; and (d) a quaternary ammonium surfactant. In some embodiments, the fluorinated surfactant is a non-ionic perfluoroalkyl sulfonyl compound.Also provided herein are methods of polishing a polycrystalline silicon surface, including providing a slurry composition according to an embodiment of the invention to a polycrystalline silicon surface and performing a CMP process to polish the polycrystalline silicon surface.
US08512590B2	Rotating machine, bonded magnet, magnet roll, and method for producing sintered ferrite magnet A method for producing a sintered ferrite magnet having an M-type ferrite structure and represented by: Ca1−x−yRxBayFe2n-zCoz, (by atomic ratio), where 0.3≦1−x−y≦0.65, 0.2≦x≦0.65, 0.001≦y≦0.2, 0.03≦z≦0.65, 4≦n≦7, and 1−x−y>y. The method includes mixing a Ca compound, an R element compound, a Ba compound, an iron compound and a Co compound as starting materials; calcining the starting materials to obtain calcined bodies; pulverizing the calcined bodies to obtain a calcined powder; providing recycled materials having an M-type ferrite structure and being represented by the above formula; pulverizing the recycled materials to obtain a recycled material powder; mixing the recycled material powder with the calcined powder to form a moldable material; molding the moldable material to obtain green bodies; and sintering the green bodies to obtain the sintered ferrite magnet.
US08512589B2	Mn—Zn ferrite core and method for producing the same Disclosed is a MnZn ferrite core comprising basic components, subcomponents and unavoidable impurities. To the basic components comprising: iron oxide (as Fe2O3): 51.0-54.5 mol %, zinc oxide (as ZnO): 8.0-12.0 mol % and manganese oxide (as MnO): remainder, are added silicon oxide (as SiO2): 50-400 mass ppm and calcium oxide (as CaO): 50-4000 ppm as subcomponents and in the unavoidable impurities, phosphorous, boron, sulfur and chlorine are respectively kept to: less than 3 mass ppm, less than 3 mass ppm, less than 5 mass ppm, and less than 10 mass ppm. The ratio of the measure specific surface area to the ideal specific surface area of the MnZn ferrite core satisfies the formula: Measured specific surface area/ideal specific surface area<1500.
US08512587B2	Highly selective doped oxide etchant Etch solutions for selectively etching doped oxide materials in the presence of silicon nitride, titanium nitride, and silicon materials, and methods utilizing the etch solutions, for example, in construction of container capacitor constructions are provided. The etch solutions are formulated as a mixture of hydrofluoric acid and an organic acid having a dielectric constant less than water, optionally, with an inorganic acid, and a pH of 1 or less.
US08512586B2	Gas cluster ion beam etching process for achieving target etch process metrics for multiple materials A method and system for performing gas cluster ion beam (GCIB) etch processing of various materials is described. In particular, the GCIB etch processing includes setting one or more GCIB properties of a GCIB process condition for the GCIB to achieve one or more target etch process metrics.
US08512585B2	Template pillar formation Methods for forming an imprint lithography template are provided. Materials for forming the imprint lithography template may be etched at different rates based on physical properties of the layers. Additionally, reflectance of the materials may be monitored to provide substantially uniform erosion of the materials.
US08512581B2	Methods for liquid transfer coating of three-dimensional substrates Methods here disclosed provide for selectively coating the top surfaces or ridges of a 3-D substrate while avoiding liquid coating material wicking into micro cavities on 3-D substrates. The substrate includes holes formed in a three-dimensional substrate by forming a sacrificial layer on a template. The template includes a template substrate with posts and trenches between the posts. The steps include subsequently depositing a semiconductor layer and selectively etching the sacrificial layer. Then, the steps include releasing the semiconductor layer from the template and coating the 3-D substrate using a liquid transfer coating step for applying a liquid coating material to a surface of the 3-D substrate. The method may further include coating the 3-D substrate by selectively coating the top ridges or surfaces of the substrate. Additional features may include filling the micro cavities of the substrate with a filling material, removing the filling material to expose only the substrate surfaces to be coated, coating the substrate with a layer of liquid coating material, and removing said filling material from the micro cavities of the substrate.
US08512580B2	Method of fabricating thin liquid crystal display device A method of fabricating a thin liquid crystal display device including a glass substrate having a flat surface. The method includes etching at least one surface of a liquid crystal display, panel, and grinding the surface of the liquid crystal display panel so as to planarize the etched liquid crystal display panel.
US08512576B2	System and method for the production or handling of heavy oil A system for the production or handling of heavy oil comprises means (18) for introducing an immiscible viscosity-reducing fluid into the heavy oil at an upstream end of a flow line (10,22) to create a dispersion of oil and viscosity-reducing fluid, and means (24,30) for separating the viscosity-reducing fluid at least partially from the oil at a downstream end of the flow line. The separating means comprises a cyclonic fluid conditioning unit (24) connected receive the dispersion of oil and viscosity-reducing fluid from the downstream end of the flow line (22), said cyclonic fluid conditioning unit being constructed and arranged to subject the dispersion to a cyclonic conditioning process; and a gravity separator unit (30) connected to receive the conditioned dispersion from the cyclonic fluid conditioning unit. The gravity separator unit (30) is constructed and arranged to allow at least partial separation of the viscosity-reducing fluid from the oil and has a first outlet for the separated viscosity-reducing fluid and a second outlet for the separated oil.
US08512564B2	Control apparatus and control method for a blood treatment equipment It is disclosed a controller for a blood treatment equipment comprising at least a treatment unit including a semipermeable membrane separating the treatment unit in a first compartment for the circulation of blood and in a second compartment for the circulation a of a treatment liquid; the controller is adapted to receive one or more entries of measured information measured during the course of a treatment procedure, calculate from said measured information a value of at least a significant parameter indicative of the progress of an extracorporeal blood treatment carried out by the equipment, wherein the controller is also adapted to compare said calculated significant parameter to at least a prescribed reference value for the same parameter, and to generate at least one output control signal responsive to said comparison for automatically controlling one or more operations performed by the equipment. The invention relates also to an equipment comprising the controller and to a control method the controller can be programmed to carry out.
US08512562B2	Drain mechanism and fluid filter including drain mechanism A drain mechanism includes: a cap that is attached detachably to a case of a fluid filter and formed with a drain hole, and includes an engaging projecting portion to which an engaging portion of a drain pipe inserted into the drain hole is engaged; and a valve member that is provided in the interior of the cap so as to close the drain hole and displaced in a direction for releasing closure of the drain hole upon contact with a tip end portion of the pipe inserted into the drain hole. The valve member is provided with a holding recess portion for holding the tip end portion of the pipe. A contact portion contacted by the tip end portion of the pipe is provided inside the holding recess portion of the valve member. When a tip end side of the engaging portion of the pipe inserted into the drain hole is in contact with a rear end side of the engaging projecting portion of the cap, an interval between a contact tip end of the engaging portion and the engaging projecting portion and an open end of the holding recess portion of the valve member closing the drain hole is longer than an interval between the contact tip end of the engaging portion and the engaging projecting portion and a tip end of the pipe.
US08512560B2	Filter press A filter press includes a press frame containing side beams (2) to support filter plates (17) movably along the longitudinal axis of the side beams (2). The filter plates (17) are oriented at right angles to the longitudinal axis of the side beams (2) and connected to one another. A pressure plate (4) can be moved along the longitudinal axis of the side beams (2) by a pushing or pulling device, and which presses the filter plates of the sliding carriage (3) against one another during the filtration process. The pushing or pulling device is mounted on a sliding carriage (3) that can be moved on the side beams (2) along the longitudinal axis of the side beams (2) by a drive unit mounted on the sliding carriage (3).
US08512552B1	Absorbent spill clean-up mat A mat for cleaning a liquid spill on a surface has a flexible, liquid-permeable outer shell having a top side, a bottom side, and a peripheral edge. The top and bottom sides are mutually fastened at a fastening area so that an interior space is segregated into a plurality of compartments, each compartment retaining an absorbent material therein. The absorbent material is preferably a powdered polyurethane foam material. In one embodiment, the absorbent material within each compartment is contained within a rectangular substantially flat inner section having a top surface, a bottom surface and a peripheral edge, such that the mat is foldable between such inner sections but not easily folded across each inner section.
US08512551B2	Forming cement as a by-product of coal liquefaction The present disclosure provides methods and systems for coal liquefaction and obtaining a cement by-product. A method of obtaining a cement by-product of coal liquefaction may include exposing a coal to a hydrogenated vegetable oil in the presence of a coal-derived solvent to form a slurry, elevating the temperature of the slurry to facilitate liquefying the coal and liberating a volatile matter, separating the insoluble components from the slurry, heating the insoluble components to liberate a volatile matter and an entrained solvent, blending the insoluble components with a calcareous material and roasting the blend in a kiln at a temperature greater than 1000 degrees Celsius to obtain a clinker, and grinding the clinker to obtain a cement.
US08512550B2	Refinery crude unit performance monitoring using advanced analytic techniques for raw material quality prediction A method for the determination of optimal pipestill operation comprising the steps of: feeding a crude oil feedstream into the pipestill wherein the crude oil feedstream is separated into boiling range fractions, performing a virtual assay of the crude oil feedstream to determine predicted boiling range fraction yields, comparing the predicted boiling range fraction yields with the actual boiling range fraction yields from the pipestill to determine differences between these fraction yields, relating the difference between the fraction yields with the operation of the pipestill.
US08512547B2	Voltammetric technique to determine the individual concentration of different antioxidants of the same class Disclosed in certain embodiments is a method of determining the individual concentration of different antioxidants of the same class in a sample comprising contacting the sample with an effective amount of phenol; and analyzing the sample by voltammetry.
US08512545B2	Porous metal article and about method for manufacturing same A porous metal article includes a substrate, a metal layer formed on the substrate, and a porous metal layer formed on the metal layer. The metal layer is a noble metal layer doped with M, M comprising an element selected from a group consisting of aluminum, magnesium and calcium, the content of M in the metal layer is between about 30 wt % and about 70 wt %. The metal layer has a thickness between about 1 micrometer and about 8 micrometers. The porous metal layer has a thickness between about 2 micrometers and about 4 micrometers.
US08512541B2	Electrolytic dissolution of chromium from chromium electrodes An electrolytic cell for replenishing chromium content of a trivalent chromium electrolyte and a method of replenishing trivalent chromium content using the electrolytic cell is provided. The method comprising the steps of immersing a chromium electrode and a second electrode in a trivalent chromium electrolyte and applying an alternating pulse current across the chromium electrode and the second electrode. In this manner, trivalent chromium is electrolytically dissolved from the chromium electrode and the trivalent chromium content of the electrolyte in which the chromium electrode is immersed is enriched.
US08512538B2	Capillary electrophoresis device This invention provides a capillary electrophoresis device in which capillaries are thermally regulated on a thermally responsive electrical path attached to an electrically insulating circuit board. This invention also provides an optical scanner useful for scanning an array of capillaries. A laser, optical detector and optical selector are in an arrangement that allows the optical detector to selectively detect an optical signal from any one or more of the plurality of electrophoresis capillaries.
US08512536B2	NOx sensor and production method thereof A NOx sensor includes a sensor element equipped with first and second pumping cells to define first and second measurement chambers. The first pumping cell exerts an oxygen pumping action against the first measurement chamber to adjust the oxygen concentration in the gas under measurement within the first measurement chamber to a given level. The second pumping cell exerts an oxygen pumping action against the second measurement chamber to produce a pumping cell current according to the NOx concentration in the gas under measurement. When the moisture content of the gas under measurement changes from 2 vol % to 8 vol %, the NOx sensor allows a variation of NOx concentration detection value based on the pumping cell current in such a manner that the NOx concentration detection value reaches a transient peak value of 20 ppm or smaller and converges to ±5 ppm of a reference value within 5 seconds.
US08512534B2	Redox polymers Novel transition metal complexes of iron, cobalt, ruthenium, osmium, and vanadium are described. The transition metal complexes can be used as redox mediators in enzyme based electrochemical sensors. In such instances, transition metal complexes accept electrons from, or transfer electrons to, enzymes at a high rate and also exchange electrons rapidly with the sensor. The transition metal complexes include at least one substituted or unsubstituted biimidazole ligand and may further include a second substituted or unsubstituted biimidazole ligand or a substituted or unsubstituted bipyridine or pyridylimidazole ligand. Transition metal complexes attached to polymeric backbones are also described.
US08512533B2	Biosensor, biosensor package structure having same, and method for fabricating same A biosensor includes a plurality of electrodes and a receptor. The plurality of electrodes comprises a plurality of carbon nanotubes. The receptor are located between the plurality of electrodes and electrically connected to the plurality of carbon nanotubes of the plurality of electrodes. In addition, the receptor reacts to a measured object to lead current variation which is transmitted by the plurality of electrodes.
US08512531B2	Gas concentration detection apparatus The present invention relates to a gas concentration detection apparatus for detecting the concentration of a specific gas component in an exhaust gas emitted from an engine, and forms a deterioration judgment about the gas concentration detection apparatus accurately and immediately. After excess oxygen is discharged by an oxygen pump cell 2, a NOx concentration detection apparatus, judges whether a NOx sensor 1 is activated. If the NOx sensor 1 is not activated yet, an output increase rate Vu(t) of the NOx sensor cell output N during an increase process of the NOx sensor cell output N is acquired. The present invention judges whether the output increase rate Vu(t) is lower than a predetermined reference value Vth1. If the obtained judgment result indicates that Vu(t)
US08512529B2	Multi-port chlorine generator A chlorine treatment apparatus includes a housing with a cavity containing a chlorine generator for chlorinating a liquid such as water and at least three openings to the cavity. The chlorine generator may be an electrolytic cell. Some embodiments may include one or more plugs for closing the openings. The plugs may be keyed to operate with only certain of the openings. Yet other embodiments may include sensors for monitoring various aspects of the liquid such as temperature, salinity, flow rate, and chlorine concentration.
US08512525B2	Valve system and method for unheading a coke drum The present invention features a coke drum de-heading system that enables the de-heading of a coke drum without having to physically remove the head units. This is essentially accomplished using one of a variety of specially designed de-header valves that may be removably coupled to a coke drum much the same way a conventional head or flange unit would be attached.
US08512524B2	Patterned framework for a papermaking belt A patterned framework for a papermaking belt is disclosed. The patterned framework has a continuous network region having a pattern formed comprising a plurality of tessellating unit cells and a plurality of discrete regions isolated from one another by the continuous network region. Each cell has a center and at least two continuous land areas extending in at least two directions from the center. At least one of the continuous land areas at least bifurcates to form a continuous land area portion having a first width before the bifurcation and at least two continuous land area portions having a second width after the bifurcation in continuous communication with the continuous land area portion. Removing and drying the embryonic web of paper fibers disposed upon the patterned framework provides a paper product having a residual water value, RW, of less than 0.12 g.
US08512523B2	Method for altering the tack of materials Methods are provided for altering the tack of an adhesive material by contacting the adhesive material with an amount of a cyclodextrin compound effective to reduce the tack of the adhesive material. In a preferred embodiment, the method is for altering the tack of adhesive contaminants in a process fluid, which includes the steps of providing a process fluid in which are dispersed contaminant particles which comprises one or more adhesive materials (such as pitch, pressure sensitive adhesives, hot melts, latexes, binders, and combinations thereof); and adding to the process an amount of a cyclodextrin compound effective to reduce the tack of the adhesive material. The process fluid can be in a process stream in a pulp and paper mill.
US08512521B2	Product for the sizing of paper The present invention relates to a paper sizing agent and emulsion comprising a maleated vegetable oil size wherein at least 50% by weight of the total fatty acids of the triglycerides are monounsaturated. The invention also relates to a process for the preparation of such maleated vegetable oil size.
US08512516B2	High solids fabric crepe process for producing absorbent sheet with in-fabric drying A method of making a cellulosic web having an elevated absorbency includes forming a nascent web having a random distribution of fiber orientation from a papermaking furnish, non-compactively drying the nascent web to a consistency of from about 30 to about 60 percent, thereafter, transferring the nascent web to a translating transfer surface that is moving at a transfer surface speed, and fabric-creping the nascent web from the transfer surface at a consistency of from about 30 to about 60 percent utilizing a creping fabric, the fabric-creping step occurring under pressure in a fabric creping nip defined between the transfer surface and the creping fabric, such that the nascent web is creped from the transfer surface and redistributed on the creping fabric to form a creped wet web. The creped wet web is dried while the web is held in the creping fabric.
US08512512B2	System and method for preextraction of hemicellulose through using a continuous prehydrolysis and steam explosion pretreatment process A method including: pretreating biomass feed stock in a first pressurized reactor, wherein the feed stock undergoes hydrolysis in the first pressurized reactor; discharging the feed stock from the first pressurized reactor to a pressurized sealing device having a first pressurized coupling to a feedstock discharge port of the first pressurized reactor; maintaining a vapor phase in the first pressurized reactor by injecting steam; washing the feed stock; draining dissolved hemi-cellulosic material extracted from the feed stock; discharging the feed stock from the pressurized sealing device through a second pressurized coupling to a second pressurized reactor; in the second pressurized reactor, infusing cells of the feed stock with steam or water vapor, and rapidly releasing the pressure applied to the feed stock to cause steam expansion in the cells of the feed stock and refine the feed stock.
US08512511B2	Mounting table and plasma processing apparatus A mounting table for use in a plasma processing apparatus, on which a substrate is mounted, includes: a conductive member connected to a high frequency power supply and a high frequency power supply; a dielectric layer embedded in a central portion on an upper surface of the conductive member; and an electrostatic chuck mounted on the dielectric layer. Further, the electrostatic chuck is connected to a high voltage DC power supply and includes an electrode film satisfying following conditions: δ/z≧85 (where δ=(ρv/(μπf))1/2) and, a surface resistivity of the substrate>a surface resistivity of a central portion of the electrode film.
US08512509B2	Plasma reactor gas distribution plate with radially distributed path splitting manifold In a showerhead assembly, a path splitting manifold comprises a gas supply inlet and a planar floor and plural gas outlets extending axially through the floor and azimuthally distributed about the floor. The path splitting manifold further comprises a plurality of channels comprising plural paths between the inlet and respective ones of the plural outlets. A gas distribution showerhead underlies the floor of the manifold and is open to the plural outlets. In certain embodiments, the plural paths are of equal lengths.
US08512506B2	Polyurethane adhesive for windshield applications An automotive windshield replacement method which includes: a) applying an adhesive to an automotive windshield and/or an automobile body substrate, said adhesive including at least one urethane prepolymer formed from reaction materials including: i) isophorone diisocyanate and/or 4,4′-diphenylmethanediisocyanate; ii) an ethylene oxide-end-capped triol having a weight average molecular weight of about 4500 to about 5000; and iii) hexanediol adipate; b) contacting the substrates together, within the working time of the adhesive, along at least a portion of the substrate(s) to which the adhesive has been applied; and c) allowing the adhesive to bond the substrates together.
US08512505B2	Methods of forming architectural resin panels with translucent veneer layers Implementations of the present invention relate aesthetically pleasing decorative architectural resin panels having a thin or brittle veneer layer, such as thinly sliced natural wood or stone. In particular, at least one implementation includes a flat or curved decorative resin panel made with a natural wood veneer layer whose structural integrity has been maintained despite being subject to various heats and pressures. The resulting resin panel is at least partially translucent, and allows for a unique display both of the resin sheets used to form the panel and of the thin wood materials encapsulated therein. Additional implementations relate to the use of other brittle veneer layers, such as translucent stone, translucent metals, or the like, which also provide unique, decorative architectural, aesthetic features.
US08512503B2	Method of manufacturing sealing device and display device using the same A sealing device including a mask for partially irradiating light and a method of manufacturing a display device using the sealing device is disclosed. The sealing device used to bond first and second substrates by interposing a sealing material at edges of the first and second substrates and by irradiating light to the sealing material comprises: a mask disposed on one side of the stage, in which a transmission portion is formed in correspondence to the formation position of the sealing member so that light can be irradiated to the sealing material; and an optical head irradiating the light to the sealing material through the transmission portion of the mask. A pattern for regulating the amount of the light irradiated to the sealing material is formed in the transmission portion of the mask.
US08512501B2	Apparatus and method for processing sealant of an insulating glass unit A method and apparatus for heating and/or pressing sealant of an insulating glass unit. The apparatus may include an oven and a press. The oven includes a detector that detects an optical property of the insulating glass unit. The detected optical property is used to regulate the amount of energy applied to the insulating glass unit to adjust the amount of energy applied to the sealant. The press may include a displacement transducer that detects a pre-pressed thickness of the insulating glass unit. The measured pre-pressed thickness is used to automatically select a press thickness from a set of pressed IGU thicknesses.
US08512495B2	Process and appartus for manufacturing tyres for vehicle wheels Building a carcass structure in the manufacturing of a tire for vehicle wheels includes associating, at each end edge of a carcass ply laying on a forming support, at least one respective annular reinforcing structure obtained by depositing at least one respective reinforcing element. The deposition of the at least one respective reinforcing element includes feeding a continuous reinforced band-like element at a cutting unit, cutting to size at least one first reinforcing element from the continuous reinforced band-like element, moving the first reinforcing element from the cutting unit toward a first end edge of the carcass ply, positioning the first reinforcing element on the first end edge, cutting to size at least one second reinforcing element from the continuous reinforced band-like element, moving the second reinforcing element from the cutting unit toward a second end edge of the carcass ply opposite said first end edge, and positioning the second reinforcing element on the other end edge.
US08512491B2	Dual wafer spin coating A method of bonding a first substrate and a second substrate includes the steps of rotating first substrate with an adhesive mass thereon, and second substrate contacting the mass and overlying the first substrate, controlling a vertical height of a heated control platen spaced apart from and not contacting the second substrate so as to control a temperature of the adhesive mass, so as to at least one of bond the first and second substrates in alignment with one another, or achieve a sufficiently planar adhesive interface between the first and second substrates.
US08512490B2	Homogeneous mesoporous nanoenergetic metal oxide composite fabrication methods The invention provides methods for making homogeneous metal oxide nanoenergetic composites. A method of the invention forms a metal oxide nanostructure via a sol-gel process with surfactant templating. Metal nanoparticles are introduced into the metal oxide nanostructure via wet impregnation.
US08512486B2	Beta-type titanium alloy and product thereof The present invention provides a beta-type titanium alloy including, by weight %: Nb: 10 to 25%; Cr: 1 to 10%; at least one of Zr: 10% or less and Sn: 8% or less, satisfying Zr+Sn being 10% or less; and the balance of Ti and inevitable impurities, the alloy having Young's modulus of 100 GPa or less, a process for producing the beta-type titanium alloy, and a beta-type titanium alloy product.
US08512480B2	Liquid detergent composition comprising a hydrophobically modified cellulosic polymer The present invention relates to a light duty liquid detergent composition comprising a low molecular weight hydrophobically modified cellulosic polymer, to provide improved foaming properties.
US08512477B2	Dishwasher and method for operating a dishwasher A dishwasher and a method for operating a dishwasher reduce the length of a washing cycle in a dishwasher as well as the noise which is generated by the impact of the water therein, without altering the performance of the dishwasher. The washing method for a dishwasher having at least two spray devices includes dividing a significant period of time of a washing program duration into a plurality of different lengths of sub-units of time. Substantially every sub-unit of time is made up of at least two time sections. During a first time section, the washing liquid passes through all of the spray devices and during a second time section, the liquid only passes through the lowermost or the uppermost spray device. A dishwasher having at least two spray devices carries out the washing method.
US08512476B2	Ultrasonic cleaning method, and ultrasonic cleaning apparatus The frequency and power of ultrasonic waves is adjusted to materialize the relation 0.04f−20.0≦P≦0.09f−7.5, wherein f (kHz) is the frequency of the ultrasonic waves and P (W/L) is the power per unit fluid volume obtained by dividing the power (W) of the ultrasonic waves by the volume (L) of a cleaning fluid. The discharge condition of the cleaning fluid by a pump is adjusted such that the proportion (C5) of the brightness of the fluid when 5 seconds has passed since the state wherein both an ultrasonic wave irradiation means and a bubble supply means are concurrently operating to the brightness of the fluid when no bubbles exist in the fluid is 0.75 or less. The coalition and crush of bubbles due to the irradiation of ultrasonic waves are suppressed, and the both actions can be utilized for a long period.
US08512471B2	Halosilane assisted PVT growth of SiC In a physical vapor transport growth technique for silicon carbide a silicon carbide powder and a silicon carbide seed crystal are introduced into a physical vapor transport growth system and halosilane gas is introduced separately into the system. The source powder, the halosilane gas, and the seed crystal are heated in a manner that encourages physical vapor transport growth of silicon carbide on the seed crystal, as well as chemical transformations in the gas phase leading to reactions between halogen and chemical elements present in the growth system.
US08512470B2	System and methods for growing high-resistance single crystals A method for growing high-resistivity single crystals includes placing a raw material in a vacuum-sealable ampoule, heating the raw material in the vacuum-sealable ampoule to vaporize the moisture in the raw material, exhausting the vaporized moisture from the vacuum-sealable ampoule, vacuum-sealing the vacuum-sealable ampoule, heating the raw material in the vacuum-sealable ampoule to vaporize the oxide compounds in the raw material, cooling a bulb in a cap on the vacuum-sealable ampoule to produce condensed oxide compounds on an inner surface of the bulb, removing the bulb and the condensed oxide compounds from the vacuum-sealable ampoule, wherein the raw material in the vacuum-sealable ampoule comprises carbon as an impurity, and placing the vacuum-sealable ampoule comprising the raw material in a crystal growth apparatus to grow a high-resistivity crystal from the raw material.
US08512465B2	Use of copolymers as adhesion promoters in lacquers The invention relates to the use of copolymers which as well as other monomers contain in copolymerized form 10% to 90% by weight of monomers containing heterocyclic basic groups, and which do not contain vinylpyrrolidone as a monomer component, as additives in paints for improving the adhesion of the solid paint film to a substrate.The invention also relates to cured and uncured polymer compositions comprising copolymers which as well as other monomers contain in copolymerized form 10% to 90% by weight of monomers containing heterocyclic basic groups, and which do not contain vinylpyrrolidone as a monomer component, as adhesion improver additions.
US08512462B2	Azo compounds, ink compositions, and colored bodies Azo compounds represented by general formula (1) or salts thereof are provided as highly water-soluble colorants which have hues of yellow, orange, brown or red, and excellent color development properties and which, when used in various recording processes, particularly in an inkjet recording process, ensure various excellent fastnesses such as light fastness, ozone fastness, and fading balance. Ink compositions containing the colorants are also provided. In general formula (1), R1 to R8 are each independently a hydrogen atom, C1-4 alkyl, C1-4 alkoxy, or the like; and X is C1-8 alkylenediamino, xylylenediamino, or the like.
US08512460B2	Carbon dioxide recovery system A carbon dioxide recovery system according to the present embodiments includes: an absorber bringing exhaust gas containing carbon dioxide into contact with absorbent reversibly absorbing or releasing carbon dioxide at above or below a predetermined temperature, and making the absorbent absorb carbon dioxide in the exhaust gas; a regenerator releasing carbon dioxide in the absorbent by heating the absorbent absorbing carbon dioxide at the absorber; a reflux pipeline flowing back the absorbent regenerated at the regenerator to the absorber; and a filter introducing at least a part of the absorbent, removing solids accumulated in the introduced absorbent, and returning the absorbent after the solids are removed to a vicinity of a portion where the absorbent is introduced.
US08512459B2	Pre-concentration device and method for ion mobility detection apparatus The present invention relates to a pre-concentration device and method for an ion mobility detection apparatus. According to an aspect of the invention, there is provided a pre-concentration device comprising: a collecting passage configured to collect a gas mixture including substances to be detected: a sieve provided, in a deploy state, within the collecting passage and configured to separate the substances from the gas mixture, the separated substances being absorbed to the sieve; at least one desorption unit configured to desorb the substances that have been absorbed to the sieve, the sieve being received in a wound state in the desorption unit; and a driving device configured to drive movement of the sieve between an absorption position in which the substances are absorbed to the sieve in the collecting passage, and a desorption position in which the substances are desorbed from the sieve in the at least one desorption unit.
US08512455B2	Electric precipitator Disclosed herein is an electric precipitator including at least one high voltage electrode including a pair of film members made of a non-conductive material and attached to each other and an electrode layer disposed between the pair of film members, and at least one low voltage electrode disposed alternately with the at least one high voltage electrode such that that the at least one high voltage electrode and the at least one low voltage electrode are separated from each other. Support members made of an insulating member to maintain separation of the at least one high voltage electrode and the at least one low voltage electrode from each other are mounted on one of the at least one high voltage electrode and the at least one low voltage electrode.
US08512451B1	Cyclone separator arrangement A cyclone separator arrangement is made by forming a hollow cylindrical wall, making an L-shaped cut beginning at a first open end of the wall to form a flap, bending the flap inwardly to form a tangential inlet, enclosing the open end of the wall, and providing an outlet tube extending through the first end into the interior of said cylindrical wall along the central longitudinal axis.
US08512448B2	Multi-stage scrubbing system and method for ethanol vent streams A multi-stage scrubbing system comprises a pre-scrubber system structured to receive a vent stream therein and pre-scrub the vent stream with a pre-scrubber fluid. The pre-scrubber system includes a first outlet for discharging a pre-scrubbed vent stream and a second outlet for discharging a discharge stream of pre-scrubber fluid. A main scrubber system is fluidly coupled to the first outlet of the pre-scrubber system for receiving and further scrubbing the pre-scrubbed vent stream.
US08512447B2	Method for purifying a chlorine supply This invention provides a method for purifying a chlorine supply that includes a chlorine component, a bromine component, and nitrogen trichloride. The method includes the steps of introducing the chlorine supply into a vaporizer, heating the chlorine supply in the vaporizer to form a vapor, and introducing the vapor into a distillation system to provide purified chlorine gas, a distillate that includes liquid chlorine and the bromine component, and a bottoms component including the nitrogen trichloride. The method also includes the steps of condensing the vapor in a reflux condenser, heating the condensate in a reboiler, removing the purified chlorine gas from the distillation system, and removing the distillate from the distillation system.
US08512443B2	Hydrogen utilization within a refinery network Hydrogen can be recovered in a refinery network using a combination of a cycling adsorber unit and a membrane separation unit. A membrane separation unit can be used to generate at least a portion of the purge hydrogen stream for the cycling adsorber unit. This can reduce the portion of the hydrogen product stream from the cycling adsorber unit required for regeneration of the adsorbent.
US08512442B2	Selective polysulfide composite membrane A composite membrane for separating a gas from a mixed gas stream includes a fibrous non-woven substrate including consolidated synthetic thermoplastic fibers, and coextensively disposed on a surface of the fibrous non-woven substrate a continuous polysulfide rubber film adhered thereto. A method of separating a gas component from a mixed gas stream includes 1) contacting a surface of the above-described composite membrane with the mixed gas stream under conditions such that a product gas enriched in the gas component diffuses through the composite membrane; and 2) collecting the product gas.
US08512441B2	Recovery of a gaseous component from a mixture of gaseous compounds A process for recovering a gaseous component comprising at least one fluorine-containing compound from a mixture of gaseous compounds. The process includes, in a separation zone (12), bringing a mixture of gaseous constituents, including at least one fluorine-containing constituent, into contact with a gas permeable separating medium (16) comprising a polymeric compound, so that a first gaseous component comprising at least one fluorine-containing constituent is separated from a second gaseous component comprising the balance of the gaseous constituents. The first gaseous component is withdrawn from the separation zone as a permeate (34) or a retentate, while the second gaseous component is withdrawn from the separation zone as the retentate (26), when the first gaseous component is withdrawn as the permeate, and as the permeate, when the first gaseous component is withdrawn as the retentate.
US08512437B2	Method of producing inorganic nanoparticles in atmosphere and device therefor Provided are a method and a device for producing nanoparticles of a low melting point material such as gold at more than 10 times faster the rate of conventional technology while maintaining the time-averaged temperature of pulse-modulated atmospheric-pressure plasma at a temperature that is low enough so as not to damage a heat-sensitive material disposed downstream. This method of preparing nanoparticles of a low melting point inorganic material in which a wire made of a low melting point inorganic material is inserted into a plasma-generating capillary tube or a plasma-generating nozzle and atmospheric-pressure high frequency plasma is generated in the capillary tube or nozzle is characterized by generating the plasma by applying a high frequency voltage possessing a waveform which exhibits its maximum value when it rises and then immediately falls, and which is pulse-modulated so that the duty ratio thereof is 10% or less.
US08512434B2	Molded monocomponent monolayer respirator A molded respirator is made from a monocomponent monolayer nonwoven web of continuous charged monocomponent meltspun partially crystalline and partially amorphous oriented fibers of the same polymeric composition that have been bonded to form a coherent and handleable web which further may be softened while retaining orientation and fiber structure. The respirator is a cup-shaped porous monocomponent monolayer matrix whose matrix fibers are bonded to one another at at least some points of fiber intersection. The matrix has a King Stiffness greater than 1 N. The respirator may be formed without requiring stiffening layers, bicomponent fibers, or other reinforcement in the filter media layer.
US08512432B2	Composite filter media A composite filter media structure includes, in an exemplary embodiment, a base substrate that includes a nonwoven synthetic fabric formed from a plurality of fibers with a spunbond process. The base substrate has a filtration efficiency of about 35% to less than 50%, measured in accordance with EN 1822 (1998) test procedure A nanofiber layer is deposited on one side of the base substrate. The composite filter media structure has a minimum filtration efficiency of about 70%, measured in accordance with EN 1822 (1998) test procedure.
US08512431B2	Fine fiber media layer Disclosed are improved polymer materials. Also disclosed are fine fiber materials that can be made from the improved polymeric materials in the form of microfiber and nanofiber structures. The microfiber and nanofiber structures can be used in a variety of useful applications including the formation of filter materials.
US08512427B2	Acrylate polyurethane chemical mechanical polishing layer A chemical mechanical polishing pad comprising an acrylate polyurethane polishing layer, wherein the polishing layer exhibits a tensile modulus of 65 to 500 MPa; an elongation to break of 50 to 250%; a storage modulus, G′, of 25 to 200 MPa; a Shore D hardness of 25 to 75; and a wet cut rate of 1 to 10 μm/min.
US08512426B2	Steam-hydrocarbon reformer improved manifold support and header box system The disclosure provides an independent support of outlet system in a steam reformer furnace. The thermal expansion of the firebox and/or header box that occurs during operation of a reformer is decoupled from the manifold. The manifold is supported independently on a separate saddle support that supports and allows the manifold to move, while the manifold is still substantially enclosed in the header box. The header box is allowed to expand thermally into different configurations without forcing a substantial change in the manifold configuration. Further, the present invention allows the transfer lines coupled to the manifold through connection tees to laterally move the manifold and reduce lateral stress on the manifold. Thus, the invention provides for independent support of the manifold that allows vertical, lateral, and longitudinal thermal expansion of associated components without overstressing the manifold and causing failures.
US08512423B2	Method for producing solid electrolytic capacitor A surface layer of an anode body containing niobium is converted into a dielectric layer by a method for a chemical formation, which comprises step I of electrolytically forming an anode body comprising niobium in a chemical forming solution containing nitric acid and phosphoric acid at a temperature within a range from 40° C. to a boiling point of the chemical forming solution, step II of heat-treating the electrolytically formed anode body at a temperature within a range from 150° C. to 300° C., and step III of electrolytically forming the heat-treated anode body in a chemical forming solution containing nitric acid and phosphoric acid at a temperature within a range from 40° C. to a boiling point of the chemical forming solution. A cathode is formed on the dielectric layer to obtain a solid electrolytic capacitor element, and the element is sheathed to obtain a solid electrolytic capacitor.
US08512421B2	Polyurethane derivatives, composition thereof and dye additives comprising the polyurethane derivatives A polyurethane derivative and a composition thereof are disclosed. The polyurethane derivative of the present invention has a structure of formula (I). The polyurethane derivative and the composition thereof can be used for increasing light fastness.
US08512419B2	Emulsion dyeing composition containing at least one phospholipid, at least one nonionic surfactant and at least one phosphate ester, and method of using same The present invention is drawn to a composition and method for dyeing keratinous substrates containing: (a) at least one phospholipid compound; (b) at least one nonionic surfactant; (c) at least one phosphate ester chosen from alkoxylated alkyl phosphate esters and alkyl phosphate esters; (d) at least one dye chosen from oxidation dye precursors and direct dyes. The compositions of the present invention may optionally contain at least one thickening agent, at least one alkaline agent, at least one fatty substance other than a fatty acid, at least one salt, and at least one oxidizing agent.
US08512411B2	Trapezoidal bone plugs and method of bone-tendon-bone ACL reconstruction A method of synthetic grafting of bone-tendon-bone autograft harvest sites using preformed synthetic trapezoidal implants. The implants are formed of tricalcium phosphate, an osteoconductive bone graft substitute and filler, which allows for simultaneous controlled absorption and promotion of osteogenesis. The implants are preferably pretreated or presoaked intraoperatively in autologous blood, or autologous conditioned plasma, or bone marrow aspirate products to enhance healing ability. The implants are trimmed to match the patellar pole shape, pressed into place in the bone voids, and oversewn to complete the procedure.
US08512409B1	Implant with outwardly extending fixation elements Described herein are devices, systems and methods for minimally-invasive treating spinal conditions. In one aspect, disclosed is an intervertebral fixation device having a housing sized to be positioned between adjacent inferior and superior vertebrae. The housing includes an internal volume defined by an inferior coupling element, a superior coupling element, and first and second sidewalls. The device includes at least one flexible element coupled to an internal surface of at least one of the inferior or superior coupling elements. The at least one flexible element projects into the internal volume of the housing when in a first configuration. The device includes at least one fixation member coupled to the flexible element and sized to extend through a corresponding aperture in the inferior or superior coupling element.
US08512408B2	Flexiable spinal implant A spinal implant for positioning in a space formed between vertebral members. The implant includes a number of sections that are pivotally attached together at pivot axes. The pivot axes include connectors that extend through at least a portion of the sections and are configured for the sections to be pivotally attached for the implant to be flexible to facilitate insertion into the space and to be configurable to the space. One of the sections may include a receptacle that is contained within the section. The receptacle has a fixed size and shape that holds bone growth material. The fixed size and shape of the receptacle prevents the bone growth from escaping during flexing of the implant.
US08512407B2	Expandable spinal interbody and intravertebral body devices A device for insertion into a spinal (intervertebral or intravertebral) space is expandable from a first circumference to a second circumference through axial compression of segments of the device, particularly once the device has been properly situated within a vertebral space. The interbody/intravertebral body device is characterized by a plurality of axially stacked, individual segments that are provided on a central insertion and deployment rod. Each segment includes a central plate or body to which are pivotally attached plate or leaf structures. Pivoting of the structures provides a collapsed or unexpanded position of the first circumference and an open or expanded position of the second circumference.
US08512405B2	Tenodesis implant and inserter and methods for using same The present invention provides a novel split barbed fixation device for tenodesis, soft tissue reattachment of tendons and ligaments to bones. The insertion device is adapted for an entirely arthroscopic approach while achieving fixation strength with ultimate pullout resistance comparable to interference screws. The device includes an integrated tendon grasper that provides for easy manipulation of the tendon arthroscopically while eliminating the need for external whip stitching of the tendon, thereby reducing preparation time. The device further includes elements that prevent the fixation implant from being destabilized or rotating during deployment and manipulation, including: a depth limiting sheath, a first implant retainer, a first implant retaining step, a tendon grasping needle tube, and an implant keyway for mating the implant to the tube. The implant itself comprises two separate portions mating along a diagonal and having barbed surface features in opposite directions, only one of which contacts the tendon.
US08512404B2	Ocular implant delivery system and method A method of inserting an ocular implant into a patient's eye, the ocular implant being mounted on a carrier, the method comprising: inserting a cannula into an anterior chamber of the eye; moving a distal exit port of the cannula into communication with Schlemm's canal; and advancing the ocular implant and carrier through an exit port of the cannula into Schlemm's canal. The invention also provides an ocular implant and delivery system comprising: a cannula comprising a distal exit port adapted to be inserted into a Schlemm's canal portion of an eye; an ocular implant; a carrier disposed within the implant and movable with the implant within the cannula; and a proximal control adapted to be operated from exterior to an eye to move at least one of the carrier and the implant when the distal exit port of the cannula is within the eye.
US08512403B2	Annuloplasty ring with wing members for repair of a cardiac valve An annuloplasty ring for repairing a cardiac valve includes an expandable support member having oppositely disposed proximal and distal end portions and a main body portion between the end portions. The proximal end portion of the support member includes a plurality of wing members that extend from the main body portion. Each of the wing members includes at least one hook member for embedding into a cardiac wall and the valve annulus to secure the annuloplasty ring in the valve annulus. The annuloplasty ring may be expanded into full contact engagement with the annulus of the cardiac valve by an inflatable balloon. Methods for repairing a cardiac valve using the annuloplasty ring are also provided.
US08512397B2	Prosthetic vascular conduit A prosthetic vascular conduit for coupling to a valve having an annular portion includes a terminal collar member, radially expandable to receive the annular portion of the valve. The collar member includes a portion which is radially contractible to capture the annular portion of the valve to couple the valve to the conduit.
US08512396B2	Device for treating a blood circulation conduit This device (10) includes an implant (20) which has a tubular endoprosthesis (30) with a radially deployable framework (36). The implant (20) includes a flexible interposition member (24) mounted movably on the endoprosthesis (30) so as to be interposed between the outer surface (40) and a blood circulation conduit (14). The device (10) includes a deployment tool (26) which can adopt a configuration for insertion of the implant (20) and a configuration for release of the implant (20). In the configuration for insertion of the implant (20), the flexible member (24) includes at least one free part (68) held axially away from the outer surface (40) in order to minimize the radial dimension of the implant (20). The free part (68) is at least partly displaceable against the outer surface (40) when the tool (26) moves from its configuration for insertion to its configuration for release.
US08512395B2	Stent with horseshoe shaped bridges In at least one embodiment, a stent includes an unexpanded configuration, a nominally expanded configuration, and a fully expanded configuration. The stent further includes a plurality of circumferential bands and a plurality of connectors connecting adjacent circumferential bands to one another. Each circumferential band has a plurality of struts interconnected by bridges. Adjacent struts form strut pairs and are connected to one another at a first end or a second end but not both. Each strut pair defines an opening between the struts of the strut pair; the bridges extend into the openings. In the unexpanded configuration, the struts are straight along their length. Also in the unexpanded configuration, the bridges include two adjacent straight segments that are connected by a u-shaped segment, and the straight segments are parallel to one another and to the longitudinal axis of the stent.
US08512393B2	Apparatus for vessel access closure Embodiments are described for closing vascular access ports, such as arteriotomies, which involve placement and deployment of an expandable device configured to prevent blood flow across a subject arteriotomy while also keeping disturbance of intravascular flow to a minimum. Suitable prostheses may comprise one or more frames constructed from lengths of flexible materials, such as shape memory alloys or polymers. Such frames may be coupled to sheetlike or tube-like structures configured to spread loads, minimize thrombosis which may be related to intravascular flow, and maintain hemostasis.
US08512391B2	Helical stent having struts in a transition zone that progressively increase in length A stent includes a central portion of helically wound undulations formed of struts, cylindrical end portions, and transition zones between the helical portion and the cylindrical portions. According to a first aspect of the invention, the torsional flexibility of the stent is maximized by having bridges connecting adjacent winding be interrupted by the maximum possible number of undulations. In a preferred design, each winding includes nineteen undulations around the circumference, bridges are provided every five undulations. According to a second aspect of the invention, uniform opening of the transition zone is achieved by altering the width, and thereby the flexibility, of a series of struts in accordance with their lengths. Specifically, the long transition zone struts are made wider.
US08512388B1	Stent delivery catheter with improved stent retention and method of making same A stent delivery catheter system having a catheter with stent releasably mounted on a stent retention portion of the catheter for delivery and deployment within a patient's body lumen, and a method of mounting the stent on the stent retention portion of the catheter. The method generally includes exposing the stent retention portion and/or the stent to a solvent, the solvent being in the vapor phase. The vapor phase solvent typically softens the stent retention portion of the catheter, and/or, in one embodiment in which the stent has a coating on the stent body, the vapor phase solvent softens the stent coating. In a presently preferred embodiment, the stent polymeric coating has a therapeutic agent, and the method of the invention prevents or inhibits disadvantageously affecting the therapeutic agent coating during mounting of the stent on the catheter.
US08512387B2	Esophageal cooling system for ablation procedures associated with cardiac arrhythmias The invention involves a system and method for an esophageal cooling system suitable for use during surgical procedures associated with the left atrium of the heart and most particularly ablation procedures associated with atrial fibrillation. The esophageal cooling system is suitable for use irrespective of whether the ablation procedure is intraoperative or catheter based. The system includes an esophageal catheter constructed and arranged to fit within the patients esophagus. Suitably located along the esophageal catheter is a phoximal balloon for occluding an upper portion of the esophagus. The phoximal balloon includes a coolant lumen for transferring temperature controlled liquid to the area where the esophagus may be in contact with the atrium of the heart. The liquid is expelled through a nozzle which directs the liquid to the inner surface of the esophagus. A suction lumen also extends through the phoximal balloon to evacuate the used coolant from the lower portion of the esophagus or gastrum of the patient.
US08512372B2	Closure device and method for sealing a puncture in a blood vessel A closure device includes an actuator movable between an initial extended position, a first position, and a second position with respect to a housing of the closure device, an inner seal configured to deploy from a distal end of the closure device when the actuator shifts from the initial extended position to the first position, a biasing mechanism configured to urge the actuator from the first position to the second position when a first pulling force is applied to the housing, and a locking member configured to deploy from the distal end of the closure device when the actuator shifts from the second position to the first position subsequent to deployment of the inner seal.
US08512370B2	Pillow with plurality of balls for relieving sinus and congestion The present invention provides a head-rest pillow that aids the user in sleeping by relieving their sinus congestion discomfort and snoring that may be associated with such congestion. The pillow comprises a core layer that has plurality of firm balls sewn in it forming compartmentalized section. The core layer is covered with a batting layer that is sewn all around the core layer for purposes of cushioning and providing comfort to the user. This combination of core and batting layer and inserted in a hollow pillow case that covers the core and batting layer, providing a head-rest pillow for a user to use.
US08512369B2	Combined rolling membrane-balloon catheter A combined rolling membrane-balloon catheter, in particular for expanding stenoses in bodily vessels, including: an outer shaft (1) and an inner shaft (4) which is axially displaceable therein, an intermediate shaft (7) situated between the inner and outer shafts (4, 1) which is likewise axially displaceable, a rolling membrane (12) which is attached in a pressure-tight manner between the distal end (2) of the outer shaft (1) and the distal end (11) of the inner shaft (4), and which may be displaced between a passive position within the outer shaft (1) and an active position which is distally expanded from the outer shaft (1) by the action of pressure, and a dilatable balloon (14) which is attached in a pressure-tight manner between the distal end (11) of the inner shaft (4) and the distal end of the intermediate shaft (7), and which may be displaced between a passive position within the outer shaft (1) and proximally in front of the rolling membrane (12), and an active position which is distally expanded from the outer shaft (1), within the rolling membrane (12), by the action of pressure.
US08512368B2	Puncture needle device for ultrasonic endoscope A puncture needle device detachably attached to an ultrasonic endoscope via a pipe sleeve including a non-circular collar, including a cylindrical connecting body into which the pipe sleeve is inserted, the cylindrical connecting body including an insertion limit portion which contacts the pipe sleeve to prevent it from being further inserted, and a non-circular collar receiving hole engaged with the collar and irrotatable relative thereto when the pipe sleeve is inserted; a sheath projecting from the cylindrical connecting body and inserted into an internal conduit of the ultrasonic endoscope; a puncture needle inserted into the sheath; and a lock member supported by the cylindrical connecting body and movable between an unlocked position allowing the pipe sleeve to insert and remove from the cylindrical connecting body, and a locked position wherein the lock member contacts the collar of the pipe sleeve to prevent it from removing from the cylindrical connecting body.
US08512366B2	Lancing device with tethered depth-control mechanism A lancing device having a housing with a proximal end, a distal end and a longitudinal axis. The lancing device also has a lancet carrier translatably supported with respect to the housing. The lancet carrier has a proximal end and a distal end. The lancing device additionally has a depth-control mechanism with a positioning tab adapted to engage the housing, and a tether secured with respect to the positioning tab and the lancet carrier.
US08512361B2	Device and a method for anastomosis Devices and methods for anastomosis are provided. The devices can include a first and a second member of a generally hollow open configuration. The first and second members may each include a rigid part and an elastic part arranged circumferentially of the rigid part. The devices may also include a connection member for interlocking the first and second members such that anastomosis is obtained at a contact area in-between the elastic parts. The methods can include arranging an elastic part inside a tubular structure at a first end of the tubular structure, folding an edge of the first end over the elastic part, and mounting the elastic part on a rigid part, forming a first member. This may be repeated at a second end of the tubular structure, forming a second member, and the first and second members may be locked to each other by a connection member.
US08512360B2	Conduits for use in placing a target vessel in fluid communication with source of blood Methods and devices for placing a target vessel in fluid communication with a source of blood and a target vessel. A conduit includes first portion adapted to be placed in fluid communication with a source of blood, such as a heart chamber, and a second portion adapted to be placed in fluid communication with a target vessel having a lumen, such as coronary artery. The first and second conduit portions are transverse to each other such that the conduit is generally T-shaped. The conduit lies on an exterior of the heart between the blood source and the target vessel and is configured to deliver blood in multiple directions into the lumen of the target vessel. For example, in an occluded coronary artery, blood flows both toward and away from the occlusion. The conduit may be flexible, rigid, collapsible or non-collapsible, and may be formed of synthetic vascular graft material, tissue, or a combination of the two. A conduit delivery device is disclosed for deploying the conduit in a target vessel and perfusing the vessel during such deployment.
US08512359B2	Surgical device A surgical device includes a first jaw and a second jaw disposed in opposed correspondence with the first jaw. The second jaw is mechanically coupled to the first jaw at a proximal end opposite a distal end. A cutting element is disposed within the second jaw, and a first driver is configured to move the cutting element proximally from the distal end toward the proximal end of the second jaw to cut a section of tissue disposed between the first and second jaws. The device may also include a stapling element disposed within the second jaw. The cutting element and the stapling element may be contiguous so as to define a cutting and stapling element, such as a wedge having a blade disposed thereon. As the wedge is moved proximally from the distal end of the second jaw to the proximal end, the wedge pushes a plurality of staples against a plurality of opposing staple guides disposed in the first jaw in order to staple a section of tissue while cutting the section of tissue.
US08512357B2	Surgical clip applier with high torque jaws Jaw blades for use in surgical clip appliers are disclosed. The jaw blades include a first leg and a second leg, each leg having a jaw integrally connected thereto and at least one inter-leg engaging member that extends from one of the first and second legs and is engageable with the other of the first and second legs. When the at least one inter-leg engaging member is engaged with the other of the first and second legs, a displacement in a first direction of one of the first and second legs causes a first corresponding displacement in the first direction of the other of the first and second legs, and such that a displacement in a second direction, opposite the first direction, of the one of the first and second legs causes a second corresponding displacement in the second direction of the other of the first and second legs.
US08512355B2	Epilator The invention relates to an epilator (10) comprising tweezers elements (12). In accordance with the invention at least the surfaces of the tweezers elements (12) are at least in part made of a basic material reinforced with a filling material for at least 30%, the filling material comprising a hardness of at least 3 on Moh's hardness scale.
US08512353B2	Surgical robot The present invention provides a surgical robot for performing surgery of the minimally invasive type on a body to be operated upon, which surgical robot includes a number of surgical arms having respective distal ends, to each of which distal ends a surgical instrument is connected for performing surgical procedures inside a human or animal body, a base element, manipulation means for manipulating the surgical arms relative to the base element for performing the surgery, and control means for controlling the manipulation means. Positioning means are provided for positioning the base element above the body.
US08512351B2	Releasable medical basket and related methods of use A device and related methods of use are provided for the capture and removal of various unwanted objects present within the body's anatomical lumens. In an embodiment of the present disclosure, the device includes a sheath, an elongate member, and a retrieval assembly connected to the elongate member and retractable within and extendable from a lumen of the sheath. The device includes one or more legs releasably connected to a portion of the retrieval assembly in response to movement of the elongate member relative to the sheath.
US08512349B2	Apparatus for measuring depth of a bone opening and related method Apparatus for measuring bone depth for determining the length of fastener to be employed in medical treatment of the bone includes an elongated inner bone probe having a bone-engaging portion and a plurality of first manually-engageable elements secured thereto. An outer sleeve overlies at least a portion of the inner bone probe and is movable with respect thereto. A second manually-engageable element is secured to the outer sleeve. The first and second manually-engageable elements may be generally ring-shaped, so as to facilitate insertion of a user's fingers. The apparatus is structured to have the bone-engaging portion of the inner bone probe pass through an opening in the bone and engage the distal exterior surface in intimate contact as a result of the first manually-engageable elements being engaged and urged away from the bone. The outer sleeve is moved generally toward the bone so as to achieve contact between the distal end of the outer sleeve and the proximal exterior surface of the bone. A reading of desired fastener length may then be made. Other embodiments of the gauge employing different configurations of the two main components and additional functional features, as well as adaptors, which facilitate retro-fitting structural features, of the present invention into prior art devices. Associated methods are provided.
US08512348B2	Surgical tool for adjusting a spinal implant A surgical instrument and/or method of using a surgical instrument during spinal surgery. The surgical instrument may find particular applicability to spinal implants for the intervertebral disc space that require relative rotation between parts in order to change the height of the implant. The instrument includes a knob that rotatable and selectively longitudinally moveable relative to a handle section. In a forward position, turning the knob turns a drive shaft that is coupled to the rotatable actuator of the implant, and causes the implant to expand or retract depending on the direction of rotation. In the rearward position, the drive shaft is retracted, and turning the knob turns a coupling shaft, distinct from the drive shaft, for decoupling the implant from the instrument.
US08512342B2	Portable bone grinder A bone grinder utilizing a removable cutter head unit for maintaining the processing of bone and for substantially precluding the main body of the bone grinder from being exposed to bone tissue.
US08512340B2	Torsional pineapple dissection tip A torsional dissection tip and method of use comprising a longitudinal-torsional resonator having a cutting surface at a distal end with cutting teeth of a pitch optimized to the torsional or longitudinal displacement of the distal tip. The present art apparatus and method of use utilizes uniquely designed cutting surface geometries with the aforesaid pitch attributes for surgical applications. Utilization of the present art torsional dissection tip allows a surgeon to easily remove hard tissues such as bone without moving the present art instrument to any site except that which is to be dissected.
US08512338B2	Photodynamic bone stabilization systems and methods for reinforcing bone Photodynamic bone stabilization systems are disclosed herein. In an embodiment, a photodynamic bone stabilization system includes a catheter having an elongated shaft with a proximal end adapter, a distal end releasably engaging an expandable portion, and a longitudinal axis therebetween; a light-conducting fiber configured to transmit light energy to the expandable portion; a light-sensitive liquid monomer comprising an initiator, wherein the initiator is activated when the light-conducting fiber transmits the light energy to initiate polymerization of the light-sensitive liquid monomer; and a cooling medium configured to control polymerization temperature, wherein the catheter comprises an inner void sufficiently designed to pass the light-sensitive liquid monomer into the expandable portion, and wherein the catheter comprises an inner lumen sufficiently designed to pass the light-conducting fiber into the expandable portion and configured to circulate the cooling medium.
US08512337B2	Method and system for treatment of atrial tachyarrhythmias A method of and a system for treatment of atrial tachyarrhythmias. The system includes a set of hemostats having elongated opposing jaws carrying mechanisms for applying ablation energy along the jaws. The jaws having straight and curved configurations selected to allow arrangement of the jaws of along opposite sides of walls of a patient's atrium. Treatment is accomplished by applying of ablation energy to the walls of a patient's artria to create lines of lesion corresponding generally to incisions employed in a Maze type procedure.
US08512335B2	High frequency alternating current medical device with self-limiting conductive material and method A high frequency alternating current medical device and method of using such is disclosed. High frequency alternating current medical device comprises a power source, an electric field generator, a self-limiting conductive material electrical component, at least one probe or needle-type projection, and at least two conductive segments located on probe or needle-type projection. At least two conductive segments are electrically connected to electric field generator so that an electric field is created between conductive segments, which induces an electrical current, which generates heat, and causes a certain desired precise cell injury. Self-limiting conductive material electrical component allows such precise cell injury because it limits electrical current through target tissue. Invention may be used in medical, dental, or veterinary applications. Exemplary embodiments include cosmetic applications, treatment of wrinkles, remodeling of subcutaneous tissue, treatment of muscle spasms, and others. Medical device can be small, hand-held, and easily manipulated to perform surgery.
US08512333B2	Anchored RF ablation device for the destruction of tissue masses The inventive ablation element comprises an elongated cannula having a proximal end and a distal end. The cannula defines an internal lumen within the cannula and a cannula axis. A plurality of conductors contained within the lumen, each of the conductors has a proximal end proximate the proximal end of the cannula, and a distal end proximate the distal end of the cannula. A plurality of ablation stylets each has a proximal end and a distal end, and each coupled at the respective proximal end of the stylet to the distal end of a respective conductor, the stylets comprise a deflectable material, the conductors together with their respective stylets being mounted for axial movement. A trocar point defined proximate the distal end of the cannula. A deflection surface positioned between the trocar point and the proximal end of the cannula, the deflection surface being configured and positioned to deflect, in response to axial movement of the stylets in a direction from the proximate end of the cannula to the distal end of the cannula, at least some of the stylets laterally with respect to the cannula axis in different directions along substantially straight paths, the paths defining an ablation volume.
US08512331B2	Electrosurgical methods and devices employing phase-controlled radiofrequency energy This disclosure relates generally to electrosurgical methods and devices. In one embodiment, an electrosurgical device is provided suitable for applying phase controlled RF energy to a treatment site. The electrosurgical device comprises a multi-electrode electrosurgical probe electrically coupled to a plurality of RF generators. Also provided are methods of use of such an electrosurgical device, as well as other electrosurgical devices. The methods and devices disclosed herein find utility, for example, in the field of medicine.
US08512322B1	Antimicrobial layer for optical output window Light-source treatment devices such as dermatological or cosmetic devices include a skin contacting surface layer that is antimicrobial. The antimicrobial skin contacting surface layer enhances the cleanliness of the device and helps reduce infection and contamination risks associated with use of the devices, particularly where the treatment of multiple individuals occurs. The antimicrobial layer may be titanium dioxide.
US08512319B2	Ophthalmic laser treatment apparatus An ophthalmic laser treatment apparatus comprises: a main unit; a laser source; a hand-held cabinet; a laser delivery optical system for irradiating the laser beam in a predetermined irradiation pattern onto tissues of the patient's eye, the laser delivery optical system including: a fiber unit connecting the hand-held cabinet to the main unit; a scanner for deflecting an optical axis of the laser beam; and an image forming optical system for forming an image of the laser beam in the form of a spot on the tissues of the patient's eye; an irradiation pattern setting unit for setting an irradiation pattern of the treatment laser beam; a control unit for controlling drive of the scanner; and a beam combiner provided in the hand-held cabinet to make an observation optical path and an optical path of the laser delivery optical system coincident with each other.
US08512316B2	Manipulator A manipulator has a treating portion, a driving portion which are connected by a connecting portion, a first pulley on which a first wire which passes through inside of the connecting portion and is driven by the driving portion is hung for rotation, and a main shaft portion which rotatably supports the treating portion around a main shaft along a direction different from a first rotor axis that the first pulley rotates, one end portion of which is fixed to the first pulley.
US08512313B2	Urinary flow control valve with pressure sealing A valve for controlling fluid flow through a flow passage. The valve includes a tubular valve body defining a longitudinal axis and having an interior surface and an exterior surface. The valve body defines first and second valve ends and a tip portion is supported on the valve body and located at the second valve end. A cap member is supported on the valve body and includes a closed end formed by an end wall having an aperture for receiving the tip portion. The aperture includes a lip portion surrounded a groove on an interior of the cap member to facilitate a pressure seal between the aperture and the tip portion.
US08512312B2	Offset catheter connector, system and method Catheter connectors, connection systems, and methods of use in which a catheter is attached to an offset connector such that the catheter is retained on the connector by compression between a tube located within the catheter and a collar fitted over the portion of the catheter containing the tube. The catheters used with the offset catheter connection systems may include an elastically compressible inner body that is surrounded by a reinforcing braid. After the offset connector tube is inserted into the lumen of the catheter, a collar may be advanced over the exterior of the catheter and the offset connecter tube contained therein.
US08512310B2	Endovascular devices and methods for exploiting intramural space Devices and methods for the treatment of chronic total occlusions are provided. One disclosed embodiment comprises a method of facilitating treatment via a vascular wall defining a vascular lumen containing an occlusion therein. The method includes providing a first intravascular device having a distal portion with a concave side, inserting the first device into the vascular lumen, positioning the distal portion in the vascular wall, and orienting the concave side of the distal portion toward the vascular lumen.
US08512309B2	Vial adapter element A vial adapter element for use in a drug mixing system including a body, a vial connection port extending from the body, a hollow vial puncturing spike that protrudes into the vial connection port and is in fluid communication with a syringe-adapter-element connection port that extends from the body, and a plurality of resilient tongues spaced around an inner wall of the body, the tongues being located in gaps formed in the inner wall of the body.
US08512307B2	Vial adaptors and vials for regulating pressure In certain embodiments, a vial adaptor for removing liquid contents from a vial includes a piercing member and a bag. The bag can be contained within the piercing member such that the bag is introduced to the vial when the vial adaptor is coupled with the vial. In some embodiments, the bag expands within the vial as liquid is removed from the vial via the adaptor, thereby regulating pressure within the vial. In other embodiments, a vial includes a bag for regulating pressure within the vial as liquid is removed therefrom. In some embodiments, a vial adaptor is coupled with the vial in order to remove the liquid. In some embodiments, as the liquid is removed from the vial via the adaptor, the bag expands within the vial, and in other embodiments, the bag contracts within the vial.
US08512301B2	Canned vacuum An apparatus includes a vacuum container for maintaining a built-in vacuum pressure, and a vacuum device for connecting the vacuum container with a surface. A method to treat patients using a disposable vacuum source is also provided, including applying the disposable vacuum apparatus to the patient's skin, equalizing the pressure in the vacuum apparatus and the pressure on the skin to apply a vacuum suction force, and releasing the vacuum suction force by equalizing the pressure on the skin with the ambient atmospheric pressure.
US08512300B1	Enteral feeding system An enteral feeding system reduces medical risk for aspirational pneumonia when an angle of the head gatch section is outside a predetermined range of 30-45 degrees. The system comprises a hospital bed having a head gatch section and an intravenous pole connected to an enteral feeding pump. The pump has a fluid sensor which operates properly when the pump is positioned along a vertical axis. The pole is connected to the head gatch section at a 30 degree angle offset from a vertical axis. In operation, when the head gatch section is positioned less than 30 degrees, the pump will stop operating and when the head gatch section is positioned at 30 degres, the pump will operate since the pump is positioned along a vertical axis to allow the fluid sensor to detect fluid.
US08512299B2	Attachment for a parenteral device An attachment for a parenteral device, the device comprising a body and an outlet for conveying fluid, the attachment comprises a housing (12) adapted for engagement with the body, an elongate hollow needle (30), having an outer end (32) and an inner end (34), with an aperture at both ends, a carrier (40) for carrying the needle, the carrier being movable relative to the housing from a first, position, at which the outer end is received within the housing, to a second position at which the outer end extends from the housing and the carrier being movable from second position to first position, and the housing having a flow path extending, when the carrier is in second position, between the outlet and the carrier, wherein the needle is open at the inner end; whereby when the carrier is positioned in second position the inner end is brought into communication with the flow path.
US08512298B2	Flush syringe having compressible plunger An I.V. flush syringe assembly includes a barrel having an inside surface defining a chamber for retaining fluid, an open proximal end and a distal end with a passageway therethrough in fluid communication with the chamber. An elongate plunger having a proximal end, a distal end and a stopper is slidably positioned in fluid-tight engagement with the inside surface of the barrel for drawing fluid into and out of the chamber by movement of the stopper relative to the barrel. The plunger includes anti-reflux structure for minimizing stopper deflection when fluid has been delivered from the chamber and the stopper is being forced against the distal end of the chamber.
US08512297B2	Pen-type injector The present invention relates to injectors, such as pen-type injectors, that provide for administration of medicinal products from a multidose-cartridge and permit a user to set the delivery dose. The injector may include a housing, a piston rod adapted to operate through the housing, a dose dial sleeve located between the housing and the piston rod, and a drive sleeve located between the dose dial sleeve and the piston rod. The dose dial sleeve may have a helical thread of first lead and the drive sleeve may have a helical groove of second lead. The first lead of the helical thread and the second lead of the helical groove may be the same.
US08512296B2	Injection device An injection device (30) features a housing (42, 52) for reception of a container (34) having a fluid (32) to be injected, a first element (94) for ejecting injection fluid (32) from such a container (34), and said first element (94) has an external thread (92). A metering element (66, 88) has an internal thread (90) that is in engagement with the external thread (92) of the first element (94), and said metering element (66) is rotatable, together with the first element (94), for preselection of a desired injection dose. A coupling arrangement (K1) serves, during an injection operation, to create a nonrotatable connection between the first element (94) and the housing (42, 52) and thereby to block, during an injection operation, a rotation of the first element (94) relative to the housing (42, 52) but to enable a rotation of the metering element (66, 88) relative to the housing (42, 52).
US08512289B2	Reservoir filling systems and methods A reservoir may be filled with fluidic media in a first type of environment, a plunger head may be placed within the reservoir in the first type of environment, and a casing that may be configured to envelop at least a portion of a plunger arm operatively connected to the plunger head may be attached adjacent to at least a portion of the reservoir in a second type of environment. A reservoir may be provided having a first and second portion for respectively containing fluidic media, the second portion may be adapted to be removable, the reservoir may be selectively filled with a first volume or a second volume of fluidic media, a seal member may be placed in the reservoir, and the second portion may be removed in a case where the reservoir contains the first volume of fluidic media.
US08512282B2	Catheter with skived tubular member An elongate shaft of a medical catheter including a thermoset polymeric tubular member including a skived distal portion. The skived distal portion includes a distally extending trough having a convex surface and a concave surface. A thermoplastic tubular sleeve may be positioned over at least a portion of the skived distal portion of the thermoset polymeric tubular member. In some instances, the thermoplastic tubular sleeve includes a crescent-shaped tubular portion defining a crescent-shaped lumen. The trough of the skived distal portion may extend through the crescent-shaped lumen. The thermoplastic tubular sleeve is thermally bonded to the inner and outer tubular members of a distal section of the elongate shaft at a guidewire port joint.
US08512279B2	Syringe The present invention relates to a syringe (1) for use in spectroscopy to identify drugs within the syringe (8). The syringe comprises a optical window section (8) either integral with or attached to the syringe (1). The optical window section (8) has predetermined physical and optical properties that allows radiation to pass through in a known manner to facilitate spectroscopy.
US08512277B2	Kit for rendering injectable dermis Volume filling and/or augmentation are improved by harvesting live dermis from a donor and processing the dermis for re-injection into the donor. A variety of kits, tools, and methods are described for harvesting, processing, and using injectable dermis in volume filling procedures.
US08512276B2	System for providing blood glucose measurements to an infusion device An infusion system includes an infusion device and a sensing device. The infusion system may further include a characteristic determining device. The infusion device also includes a communication system for transmitting to and receiving communications from the sensing device or a computer. The sensing device may sense an analyte of a bodily fluid of the user. The analyte may be calibrated using data from the infusion device and from a characteristic determining device. The system may be set up to automatically call for assistance when analytes reach a certain level.
US08512271B2	Device and method for determining a dialysis fluid flow rate for extracorporeal blood treatment The present invention relates to a device and to a method for determining the dialysis fluid flow rate for an extracorporeal blood treatment device. The dialysis fluid flow rate Qd is determined in accordance with the blood flow rate Qb or the blood flow rate Qb is determined in accordance with the dialysis fluid flow rate Qd, wherein by increasing about a specific value, the increase of a variable characterising the efficiency of the blood treatment, in particular clearance K, does not exceed the specific value. The present invention also relates to a blood treatment device comprising a device for determining the dialysis fluid flow rate or blood flow rate and to a method for operating an extracorporeal blood treatment device. As a result, an optimal dialysis fluid flow rate and/or blood flow rate calculates the requirement in accordance with a high efficiency of the dialysis treatment and in accordance with a reduced consumption of the dialysis liquid.
US08512270B2	Dynamic foot-arch support assembly and associated methods The technology described herein provides a dynamic foot-arch support assembly for dynamically supporting the arch and structures of the human foot throughout phases of the biomechanical movement of the foot during weight-bearing activities. A dynamic foot-arch support assembly for supporting the arch and structures of a foot is provided that includes a support band having an upper end and a lower end, the support band forming a loop at the upper end through which to place a foot and position the loop around or just below an ankle portion of the foot, the lower end configured to wrap from an inside area of the ankle portion of the foot and rotate to an underside of the foot for secure attachment below the underside of the foot, the support band thereby configured to provide a tension to support an arch area of the foot, and a shoe sole, the lower end configured secured to the shoe sole.
US08512268B2	Orthopedic auxiliary aid comprising an introduceable functional element The invention relates to an orthopedic auxiliary aid such as a bandage, orthesis, splint, support, compressive clothing and/or knitted item or similar for the therapy or support of corresponding body parts, comprising a functional element have additional therapeutic effects. Said orthopedic auxiliary aid is a compressive knitted part that comprises at least one receiving device for the additional functional element and at least one opening that is embedded in the knitted item allowing access to the receiving device, said opening does not negatively modify the compression properties of the auxiliary aid.
US08512266B2	Orthopedic adjustment device An exemplary orthopedic adjustment device includes an orthopedic appliance, an adjustment unit module and a pressure control module. The appliance is configured for supporting a human spine. The adjustment unit module includes adjustment units. Each of the adjustment units includes a chamber, a pressure sensor and a pump. The pressure sensor and the pump are arranged in the chamber. Each of the pressure sensors is configured for detecting a pressure of each chamber corresponding thereto. Each of the pumps is configured for adjusting the pressure of each chamber corresponding thereto. The pressure control module is configured for receiving pressure signals from the pressure sensors of the chambers and providing pressure adjusting signals to the pumps to adjust the pressures of the chambers.
US08512261B2	Perineal elasticity meter A Perineal elasticity meter having a circular central stem marked with millimeter markings and a sleeve portion surrounding the circular stem. Hinges connect the sleeve to expanders that extend from the circular stem. The perineal elasticity meter is configured to be inserted into the vagina of a patient in order to measure the elasticity of the perineal area. The sleeve includes an opening that shows a circumferential measurement achieved by the expansion of the expanders, as the sleeve moves along the central stem. Another perineal elasticity meter includes two stems connected via a hinge at a proximal portion of the stems. The proximal portions of the stems are configured to be inserted into the vagina of a patient and a measurement is taken of a distance between the expanded distal portion of the stems, thereby measuring the elasticity of the perineal area.
US08512260B2	Statistical, noninvasive measurement of intracranial pressure Tools and techniques for the rapid, continuous, invasive and/or noninvasive measurement, estimation, and/or prediction of a patient's intracranial pressure. In an aspect, some tools and techniques can predict the onset of conditions such as herniation and/or can recommend (and, in some cases, administer) a therapeutic treatment for the patient's condition. In another aspect, some techniques employ high speed software technology that enables active, long term learning from extremely large, continually changing datasets. In some cases, this technology utilizes feature extraction, state-of-the-art machine learning and/or statistical methods to autonomously build and apply relevant models in real-time.
US08512258B2	Breath test device and method There is provided a method of evaluating a liver condition of a subject, the method includes computing a fluctuation parameter from a liver breath test based on at least one of a percentage dose recovery (PDR) curve and a delta over baseline (DOB) curve of an isotope labeled methacetin, or a salt or a derivative thereof, and evaluating at least one liver condition of the subject, based at least on the fluctuation parameter. There is provided herein a method of evaluating a liver condition of a subject, the method includes computing a hepatic impairment score based at least on a breath test related parameter and on a demographic parameter.
US08512257B2	Implantable cardiac event detection device with an adaptive sleep state Disclosed is a system for the detection of cardiac events (a guardian system) that includes an implanted device called a cardiosaver, a physician's programmer and an external alarm system. The system is designed to provide early detection of cardiac events such as acute myocardial infarction or exercise induced myocardial ischemia caused by an increased heart rate or exertion. The system can also alert the patient with a less urgent alarm if a heart arrhythmia is detected. Using one or more detection algorithms, the cardiosaver can detect a change in the patient's electrogram that is indicative of a cardiac event within five minutes after it occurs and then automatically warn the patient that the event is occurring. To provide this warning, the guardian system includes an internal alarm sub-system (internal alarm means) within the cardiosaver and/or an external alarm system (external alarm means). If the guardian system is put into a pacemaker, the algorithm can utilize a different analysis of the electrogram depending on whether or not the pacemaker is actually pacing the heart.
US08512252B2	Delivery method and system for monitoring cardiovascular pressures A delivery method and system for noninvasively monitoring cardiac physiologic parameters used to evaluate patients with cardiovascular conditions. The system includes an implantable sensing device configured for chronic implantation in a cavity of the cardiovascular system, such as the heart, pulmonary artery (PA), etc. The method involves introducing the sensing device through a cardiovascular cavity that is upstream in the vasculature from the cavity where implantation is intended and has a larger diameter than the intended cavity, and thereafter blood flow through the cardiovascular system delivers the device to the intended cavity. The device is sized and configured so as to secure itself within the intended cavity when the device moves through the cavity to a point where the diameter narrows sufficiently to secure the device and so as to be oriented once secured to sense a pressure either within, upstream (wedge), or downstream (distal) of the cavity.
US08512246B2	Method and apparatus for providing peak detection circuitry for data communication systems Method and apparatus for providing a peak detection circuit comprising a diode including an input terminal and an output terminal the input terminal of the diode configured to receive an input signal, a capacitor operatively coupled to the output terminal of the diode, an output terminal operatively coupled to the capacitor and the output terminal of the diode for outputting an output signal is provided. Other equivalent switching configuration is further provided to effectively detect and compensate for a voltage droop from a power supply signal, as well as to electrically isolate the voltage droop from the system circuitry.
US08512244B2	Integrated analyte sensor and infusion device and methods therefor Method and system for providing an integrated analyte monitoring system and on-body patch pump with multiple cannulas and a sensor combination is provided.
US08512237B2	Medical device for colo-proctological pathologies A medical device 1 for colo-proctological pathologies, comprising a retractor body 2, having a distal end 3 and a proximal end 4, a handle 7 connected to the retractor body 2, and illuminating means 16, located internally of a cavity 12 fashioned internally of the proximal end 4, for generating a light beam internally of the retractor body 2.
US08512233B2	Curved laryngoscope and operation instrument assembly applying the same A curved laryngoscope and an operation instrument assembly applying the same are provided, wherein the curved laryngoscope is provided with a guiding structure and a locating device. The guiding structure and the locating device can be individually or both adopted in the curved laryngoscope to assist various operation instruments in moving and being located reliably, and therefore improve the reliability, accuracy and facility in operation using the curved laryngoscope.
US08512232B2	Endoscopic illumination system, assembly and methods for staged illumination of different target areas The inventive subject matter is generally directed to an illumination system for staged illumination in an endoscopic procedure. The inventive system generally includes an illumination apparatus supporting a light source that is configured for removable assembly with an endoscope. The assembly is configured for insertion into a natural or artificial passageway in a body. The illumination apparatus has one or more light sources providing a first, relatively high level of illumination suitable for imaging a first, relatively large target area, either alone or in combination with a light source for the endoscope, and after removal of the illumination apparatus from the assembly, the endoscope provides a second relatively lower level of illumination suitable for imaging a relatively small target area.
US08512230B2	Attachment and detachment mechanism An attachment and detachment mechanism includes convex and concave engaging portions provided in first and second couplings respectively and extending in a radial direction of first and second shaft portions, the convex engaging portion is to be slidably inserted into and removed from the concave engaging portion along a longitudinal direction of the concave engaging portion, the convex and concave engaging portions includes basic positions where the longitudinal directions of the convex and concave engaging portions correspond to the attachment and detachment direction of the first and second main body portions and the convex and concave engaging portions are insertable into and removable from each other, and the attachment and detachment mechanism further includes a guide mechanism to guide one engaging portion such that the one engaging portion is disposed at the basic position in conjunction with the attachment or detachment of the first and second main body portions.
US08512228B2	Rigidizable linkage mechanisms and systems for modifying an articulating force A rigidizable linkage mechanism comprises a plurality of serially arranged links comprising a distal link and a link proximal to the distal link. The rigidizable linkage mechanism further comprises a cable that extends in a distal direction through the plurality of serially arranged links, extends around the distal link of the plurality of links, and in a proximal direction back through at least a portion of the plurality of links. A distal end of the cable is fixedly coupled to the link proximal to the distal link, and a proximal end of the cable is coupled to a rigidizing actuator.
US08512227B2	Apparatus for assisting operations of medical instrument attached to endoscope An apparatus is provided which assists operations required for a medical instrument. A tubular portion and a therapeutic member of the instrument are inserted through a channel of an insertion tube of an endoscope. In the apparatus, a first drive unit enables the therapeutic member to perform the desired therapeutic operations responsively to a first command signal and a second drive unit enables the tubular portion inserted in the channel to convey responsively to a second command signal. An input device is provided at which two kinds of commands are allowed to be inputted command by command. The two kinds of commands allow the therapeutic member and the tubular portion to be driven in parallel with each other. A controller provides the first and second drive units with the first and second command signals, respectively, in accordance with the two kinds of commands.
US08512226B2	Sexual aid device and method A sexual aid device and method for inserting and occupying space within a human female's vagina to provide a sensation of increased fullness to the female and a sensation of increased tightness and friction to a penis of a human male during sexual intercourse, thereby enhancing sexual arousal of both the female and the male. The sexual aid can be a member having a bulbous end for insertion and a tapered end for externally grasping and manipulating the member. The tapered end may include a hooked protrusion for providing anal stimulation to the female. The member may contain one or more vibrating devices. The member may further include a generally planar surface featuring a trough and can include two arced terminuses oriented in opposing directions. An internal pellet-rotating device may be installed within the tapered end of the member to produce mechanical friction in and around the vagina.
US08512221B2	Automated treatment system for sleep Automated behavioral methods and systems for treating Insomnia that use passive means for determining wake/sleep states.
US08512216B2	System for and method of filling a container with hazardous waste A method for filling a container with hazardous waste includes moving the container to a first location where a filling head adds the hazardous waste to the container, vents air from the container, and mixes the hazardous waste in the container. A lid is coupled to the container while it is at the first location.
US08512214B2	Pressure reducing folding system A method for folding sheets of a medium is provided. The method includes rotating a cam mechanism through a first period of rotation to cause a crease blade to move in a contact direction to create a crease in the sheets by pushing the sheets between a pair of first rolls, and rotating the cam mechanism through a second period of rotation to cause the crease blade to move in a retracting direction away from the sheets and cause a lever to move first and second scissor arms such that the pair of first rolls is separated and a pair of second rolls is separated. One of the second rolls is movable by the second scissor arm.
US08512212B2	Adjustable press arm apparatus and methods for exercise machines Adjustable press arm apparatus and methods are disclosed. In one embodiment, an exercise machine includes a load, a force-transferring assembly operatively coupled to the load, and a movable press arm operatively coupled to a press arm adjustment assembly that is selectively engageable with the force-transferring assembly. The press arm adjustment assembly includes a moveable swing member having an indexing portion, and an engagement device coupled to and moveable with the swing member, the engagement device being adapted to operatively engage the force-transferring assembly. A locking device is coupled to the press arm and moveable between first and second position to selectively coupled and uncouple the press arm from the load.
US08512210B2	Multitrainer for swivel chairs on castors A limb-exercising system for attaching to an office swivel chair on castors, the limb-exercising system including a rigid platform, at least one interchangeable limb-exercising unit, a force resistor, and a cable, the rigid platform being coupled with the castors of the office swivel chair, such that the relative movement between the rigid platform and the office swivel chair is minimal, the interchangeable limb-exercising unit being coupled with the rigid platform, the interchangeable limb-exercising unit being operative to provide movement exercise for at least one muscle group of the body of a user, the force resistor being coupled with the rigid platform and with the interchangeable limb-exercising unit, the force resistor providing resistance to movement of the interchangeable limb-exercising unit, the cable being coupled between the interchangeable limb-exercising unit and the force resistor.
US08512209B2	Device for analyzing and monitoring exercise done by a user A device for analyzing and monitoring exercise done by a user comprises at least a portable support (2), electric power supply means, sensor means (3) for measuring the exercise done by the user during at least one predetermined period of time, expressed at least in the form of at least one non-dimensional parameter, at least one memory (4) designed to archive data relating to the measurement of exercise done by the user, display means (5) for displaying the measurement of the exercise done by the user and the data archived in the memory, data communication means (6a), (6b) and at least one processing unit (7a), (7b).
US08512208B2	Braking system for a utility vehicle which can be coupled pneumatically to a trailer and method for operating such a braking system A braking system and method provided for a utility vehicle pneumatically coupled to a trailer. The system has an electronic control unit, a valve device that can be electrically connected by the at least one electronic control unit, the valve device building up pressure for the trailer braking system when connected, causing the trailer to brake, and a pressure sensor which detects the pressure for the trailer braking system and transmits a corresponding signal to the electronic control unit. The electronic control unit can influence the pressure generated for the trailer braking system by pulsed connection of the valve device, taking into account the pressure detected by the pressure sensor for the trailer braking system. The electronic control unit only allows the pulsed connection for braking the trailer when the service brake of the traction-vehicle is not activated, when conditions are such that the braking of the trailer could be useful in spite of a non-active service brake of the traction-vehicle, and when such an anti-jackknifing process is required by a signal generator.
US08512204B2	Method and apparatus effecting torque transfer through a transmission during engine autostop and autostart events A powertrain system includes an engine coupled via an input member to a transmission to transfer torque to an output member. The engine is configured to execute an autostop event and an autostart event during ongoing powertrain operation. The transmission includes a plurality of planetary gear sets and a plurality of torque transfer clutches. The plurality of torque transfer clutches includes hydraulically-activated clutches and mechanical clutch devices, including an electromechanically-activated selectable one-way clutch. The transmission is configured to provide hydraulic pressure to activate the hydraulically-activated clutches using only a mechanically driven hydraulic pump. The transmission is configured to effect torque transfer among the input member, the plurality of planetary gear sets and the output member in one of a plurality of fixed gear states by selectively activating at least one of the plurality of torque transfer clutches.
US08512202B2	Shift controller and shift controlling method A shift controller controls a transmission for a hybrid vehicle in which: an engine and a motor are connected together via a clutch; and the transmission is placed between the motor and driving wheels. The shift controller has: a first shift controlling unit which performs shift control on a basis of at least one of transmission efficiency of the transmission and power generation efficiency of the motor in a case where regeneration is performed with the clutch disengaged during deceleration of the hybrid vehicle; and a second shift controlling unit which performs shift control to make a transmission gear ratio of the transmission smaller than in the shift control performed by the first shift controlling unit in a case where the regeneration is performed with the clutch engaged during the deceleration of the hybrid vehicle.
US08512200B2	Method for operating a hybrid drive of a motor vehicle In a method for operating a hybrid drive of a vehicle having at least one internal combustion engine and at least one first electric machine as drive machines of a first drive train of the vehicle, and an associated first transmission, the total torque of the drive machines is adapted in a shifting operation of the transmission in order to reduce the load at the transmission and/or in order to modify rotational speeds according to the new transmission ratio, and/or the torque gradient of the drive machines is restricted to a specifiable, maximum torque gradient of the resulting total torque of the drive machines of the first drive train in a transition between acceleration operation and trailing throttle operation.
US08512199B2	Minimizing backlash utilizing series elastic elements Certain embodiments of a system for reducing backlash include a mechanical input, a mechanical output, and first and second mechanical couplers each connected to the mechanical input and the mechanical output. An exemplary system includes an elastic element connected in series between the first mechanical coupler and the mechanical output to bias the first mechanical coupler in a first direction and an elastic element connected in series between the second mechanical coupler and the mechanical output to bias the second mechanical coupler in a second direction, where the second direction is opposite from the first direction.
US08512196B2	Multi-speed transmission A transmission includes an input and output member, four planetary gear sets each having first, second and third members, five interconnecting members continuously interconnecting members of the four planetary gear sets and six torque transmitting mechanisms selectively engageable to interconnect one of the first members, second members, and third members with at least one of another of the first members, second members, third members, and a stationary member. The torque transmitting mechanisms are selectively engageable in combinations of at least three to establish at least eight forward speed ratios and at least one reverse speed ratio between the input member and the output member.
US08512192B2	Lubrication device for a planetary gear A lubrication device for a planetary transmission with a plurality of planetary gearsets in which a ring gear carrier, which supports a ring gear of a first planetary gearset, is connected to a planetary gear carrier which supports a plurality of planetary gears of an adjacent, second planetary gearset, and in which a lubricant supply for the planetary gears of the second planetary gearset is provided. To provide an inexpensive, simply designed and reliable lubricant supply to the planetary gears of the web carrier coupled to the ring gear of the other planetary gearset, the ring gear is sealed relative to the ring gear carrier of the first planetary gearset and relative to the planetary gear carrier of the second planetary gearset.
US08512190B2	Reversible variable transmission-RVT The invention provides a new type of reversible variable transmission for vehicles such as cars, busses, trucks, off-road vehicles, lift trucks, telescopic boom handlers and the like. Alternatively, the gearbox can be used in systems such as wind-mills etc. and other industrial applications that require power to be transferred at variable speeds.
US08512187B2	Multi-mode drive unit Multi-mode operation is provided for an electrically variable transmission for a motor vehicle. The multi-mode electrically variable transmission provides for multiple gear ratios and power flow configurations including fixed gear operation. An improved input-split planetary gear set configuration is provided for the multi-mode electrically variable transmission. The multi-mode electrically variable transmission may be operated in its desired efficiency and/or performance range more frequently. Further, the transmission reduces clutch torques and provides improved functionality in range-extended electric vehicles and battery electric vehicles. The multi-mode electrically variable transmission is provided with a fixed gear operating capability for improved highway cruising and incorporates a reverse gear for reverse operation.
US08512184B2	Tensioning device with restraint system A tensioning device for a flexible driving means, in particular a chain tensioner for a timing chain of an internal combustion engine, with a housing, a tensioning piston guided in a piston bore of the housing and a latching element arranged outside on the housing, is provided. A latching profile is provided on the front region of the tensioning piston in the tensioning direction. The latching element has at least one spring arm protruding over the housing in the tensioning direction, which engages the latching profile of the tensioning piston outside of the housing. The latching element for the delimitation of the free working range between a front end-stop and a rear end-stop in and against the tensioning direction is arranged movably on the housing.
US08512183B2	Belt drive system assembly and tension apparatus A belt assembly and adjustment mechanism for a belt drive system including a belt. The belt assembly and adjustment mechanism includes a first bracket that is attachable to a first portion of the belt drive system, and a second bracket that is attachable to a second portion of the belt drive system. The second portion is different from the first portion. The mechanism also includes a belt drive system component that is positioned between the first bracket and the second bracket. The component is pivotally coupled to the first bracket on one side of the component and is pivotally coupled to the second bracket on another side of the component. The component is further slidably coupled to one of the first bracket and the second bracket such that the component is movable between a first orientation at which the belt is configured to be tensioned and a second orientation at which the belt is configured to be installed on the component.
US08512181B2	Power unit for small vehicle A power unit including an internal combustion engine with a crankshaft and a power transmission system. The power transmission system being equipped with a belt-type continuously variable transmission having a drive shaft and a driven shaft. The belt-type continuously variable transmission being disposed below the axis of the crankshaft wherein the torque from the crankshaft is transmitted to the drive shaft for rotating the crankshaft and the drive shaft rotate in opposite directions. An output shaft, linked and interlocked with the driven shaft via a gear transmission system, is disposed above the continuously variable transmission. A gear transmission mechanism includes a single idle shaft, which has an axis parallel to the crankshaft, and being arranged between the driven shaft and the output shaft for rotating the driven shaft and the output shaft in the same direction.
US08512172B1	Baseball training apparatus and method A baseball training apparatus occludes peripheral vision of each eye across the nose region of a baseball player by creating a visual divide that extends from and immediately adjacent to the nose along the central sagittal plane. In various embodiments, the visual divide is extendible, removable and replaceable, pivotal, and may incorporate scribes to vary shape or geometry. The visual divide may further be mounted from a pair of glasses without lenses, though other embodiments with and without lenses are contemplated. The eye divider is used to align or confirm alignment of a baseball player properly with the pitcher, to ensure that the batter has both eyes facing the pitcher.
US08512169B2	Green repair tool, golf accessory, and combination golf ball marker retention and green repair tool device A golf accessory for retaining a marker therein, the accessory having a body, the upper end thereof including a semi-circular recess dimensioned to receive a removable metallic ball marker fixedly retainable within the recess. The accessory includes a pair of spaced prongs contiguous with and extending downward from the lower end of the body to prong tips, a first plurality of magnets embedded in the body adjacent the semi-circular recess, and a second plurality of magnets embedded in the spaced prongs.
US08512165B2	Multi-piece solid golf ball A multi-piece solid golf ball is composed of a solid core encased by a cover of one or more layer, which solid core has an inner core layer and an outer core layer. The inner core layer is formed primarily of a thermoplastic resin, and has a cross-sectional hardness difference of within ±5 between any two points on a cross-section obtained by cutting the inner core layer in half. The outer core layer is formed of a rubber composition made primarily of polybutadiene rubber. The solid core has a diameter of from 35 to 42 mm. The ball has specific relationships between the hardness of the inner core layer 1 mm inside a boundary between the inner core layer and the outer core layer, the hardness of the outer core layer 1 mm outside the boundary, and the surface hardness of the outer core layer.
US08512162B2	Golf simulation apparatus and method for the same It is an object of the present invention to provide a golf simulation apparatus and a method for the same, which reproduce the trajectory of a golf ball hit by a golfer to give a sense of reality to the golfer by identifying a current golf club and applying information about the identified golf club in a simulation result, the object can be accomplished by the provision of a golf simulation apparatus for simulating a golf course, including a sensing unit for sensing at least one of a golf ball hit by a golfer and a golf club used by the golfer in a simulated golf course, a club identification unit for identifying the golf club used by the golfer in the simulated golf course, and a simulation unit for simulating.
US08512156B2	Sliding ball type constant velocity joint for vehicle A sliding ball type constant velocity joint for a vehicle, and more particularly, to a sliding ball type constant velocity joint for a vehicle, which can absorb idle vibration generated from the vehicle during idling by creating a clearance between an outer spherical surface of an inner race and an inner spherical surface of a cage. The sliding ball type constant velocity joint includes a shaft which receives rotational power from an engine and rotates, an outer race which is installed at an end of the shaft and having grooves formed therein, an inner race installed in the outer race, a plurality of balls for transmitting the rotational power of the outer race to the inner race, and a cage for supporting the balls, wherein a center of a radius of an outer spherical surface of the inner race is formed at a different location from a center of a radius of an inner spherical surface of the cage.
US08512150B2	System and method for collecting and using player information A distributed computer system is provided for collecting player information. Further, a scoring system is provided that rates a player based on one or more elements of the collected information. Players may be rated with respect to a number of characteristics. Responsive to a determined rating or score, action may be taken by the distributed system with regard to the player. For instance, the player may be provided a complimentary offer, provided an award, and invitation to come to a gambling location, presented an advertisement, or other action may be performed involving the player. Further, the distributed computer system may permit a player to manage their frequent player accounts and receive complimentary offers based on a set of criteria specified by the player.
US08512149B2	Systems, methods and devices for providing an indication of an amount of time a wagering game may be expected to be played given a specified bankroll or an estimated bankroll which may be expected to be necessary to fund play of a wagering game for a specified amount of time In one embodiment, a method provides for providing a game advisory notice to players of a wagering game. The game advisory notice may comprise, for example, an estimated amount of play time that can be expected to be achieved given a specified bankroll for the wagering game. In another example, the game advisory notice may comprise an estimated bankroll that is expected to be sufficient to fund a specified amount of play time for the wagering game.
US08512146B2	Casino table game yield management system The casino table yield management data processing system has a minimum bet change recommendation generator receiving casino table occupancy and player betting data and generating recommendation data based on casino game operations model data and business rule data. A timing filter determines when recommendation data is to be presented to an operator. A quantification filter calculates revenue value data of implementing a minimum bet change and determining whether recommendation data is to be presented to an operator.
US08512143B2	Third party control over virtual world characters A method and system provides arrangements creating a relationship between a real-world entity and a virtual world environment. A participant or player can participate in various virtual world experiences including activities, settings, events, purchases, sales and diverse transactions to acquire virtual products, virtual services, and/or virtual items of value. Feedback may be provided and records kept regarding the virtual world participation. In some circumstances, multiple persons can participate as a group or participate as individuals in the virtual world environment. Some embodiments provide an oversight procedure that enables a supervisory entity to exercise direct or indirect control over certain virtual world aspects of a participant or player. In some implementations the oversight procedure is at least partially based on an attribute related to the participant or player.
US08512136B2	Game device, game control method, information storing medium, and program A game device (201) includes a signature memory unit (203), status memory unit (204), input receiving unit (202), restarting unit (205), and advancing unit (206). The signature memory unit (203) stores players' signature patterns. The status memory unit (204) stores game progress statuses for players. The input receiving unit (202) receives a trace input by players. When the received trace is similar to one of the signature patterns and the current player differs from a player (next player) associated with the signature pattern, the restarting unit (205) stores the current game progress status in the status memory unit (204) in association with the current player, and restarts the game from the game progress status stored in the status memory unit (204) in association with the next player. When the trace is similar to none of the signature patterns, the advancing unit (206) advances the game based on the received trace.
US08512130B2	Gaming system with linked gaming machines that are configurable to have a same probability of winning a designated award A gaming system that is controlled by a central controller and includes a plurality of gaming machines. Each of the gaming machines includes a game operable upon a wager by a player, a plurality of winning symbol combinations including a designated winning symbol combination and a probability of achieving the designated winning symbol combination. At least two of the gaming machines have different probabilities of achieving the designated winning symbol combination. The gaming system includes a designated award and a triggering event. After an occurrence of the triggering event, the central controller is programmed to change the probability of achieving the designated winning symbol combination for at least one of the gaming machines such that each gaming machine has an equal probability of generating the designated winning symbol combination.
US08512124B2	Gaming machine and method A gaming machine for providing a game in which a plurality of symbols are selected and displayed in an array of symbol positions on a display, each symbol position associated with one or more of a plurality of regions and each region of the plurality of regions associated with a region specific award. The gaming machine comprises a user interface in communication with a game controller. If a winning combination of symbols occurs such that at least one of the symbols of the winning combination of symbols is displayed in a symbol position associated with a first region of said plurality of regions, the region specific award associated with the first region is awarded. If the same winning combination of symbols occurs such that at least one of the symbols of the winning combination of symbols is displayed in a symbol position associated with a second region of said plurality of regions, the region specific award associated with the second region is awarded.
US08512117B2	Methods and apparatus for managing network linked gambling video games Methods and apparatus for team play in video games is provided. One method includes receiving a request to initiate a gambling game for a player of a first networked machine and joining a second player of a second networked machine to a team. The method further enables transfer of currency between the first and second players of the team using the networked machines during play of the gambling game. The method debits an account of a player using the networked machine that transferred the currency and credits an account of a player that that received the currency. The method further enables wagers in the gambling game using the credited currency, and the method is executed by at least one processor.
US08512116B2	Methods of managing play of wagering games and systems for managing play of wagering games Poker card game deals four cards to a player, four cards to a dealer, and three community cards. Player discards one card and bets 1×-4× ante wager. After a first community card is exposed, player bets 1×-3× ante wager. After a second community card is exposed, player bets 1×-2× ante wager. A final community card is exposed. Dealer reveals dealer's best five-card poker hand formed from any of dealer's four cards and three community cards, and player reveals player's best five-card poker hand formed from any of player's three cards and three community cards. Highest ranking hand wins. Pays ante wagers according to a paytable. Pays even money on play wagers. Allows side wager that pays according to a paytable. Played with one deck of cards. Includes card game method, device-readable storage medium containing device-executable code, and device-executable code stored on a device-readable storage medium.
US08512111B2	Vehicle cowl box structure A vehicle cowl box structure is provided basically with an air inlet, an air outlet, an air passageway and a flow restriction device. The air inlet is arranged to receive outside air. The air outlet is arranged to convey the outside air to a vehicle HVAC system. The air passageway extends between the air inlet and the air outlet to convey the outside air from the air inlet to the air outlet. The flow restriction device is disposed in the air passageway at a point between the air inlet and the air outlet. The flow restriction device is configured and arranged to automatically decrease airflow from the air inlet to the air outlet as the airflow through the air inlet increases.
US08512110B2	Air distribution duct in the passenger compartment of a motor vehicle The invention relates to an air distribution duct (2) integrated in the passenger compartment of a motor vehicle comprising at least one rigid hollow crossmember (1) that reinforces the structure of the vehicle, characterized in that the duct (2) is made by extrusion and is placed in the crossmember (1) at a distance from the inside wall of the crossmember.
US08512107B1	Field dressing knife A knife includes a body that includes a handle section, a blade housing section, and a blade that includes a skinning edge and a cutting edge. The guided skinning edge extends below a bottom edge of the blade housing section, wherein proximity of the bottom edge to the guided skinning edge enables the bottom edge to function as a guard that prevents the skinning edge from entering a carcass deep enough to damage meat and internal organs of the carcass during field dressing. The hook cutting edge extends above a top edge of the blade housing section, wherein the top edge terminates in a hook portion that extends beyond the hook cutting edge and lifts skin and hide of a carcass away from meat and internal organs of the carcass as the cutting edge is moved through the carcass during field dressing, preventing the cutting edge from contacting meat and internal organs of the carcass.

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