最新美国发明专利第2013-03-05期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

Document	Document Title
US08390037B2	Gas sensor A gas sensor having at least one gas-sensitive electrically conductive layer having a surface region which can be brought into contact with a target gas and in which the work function depends on the concentration of the target gas in contact therewith. At least one electrical potential sensor is capacitively coupled to the surface region via an air gap. The surface region is structured by at least one recess in which a flat material element which is connected to the gas-sensitive layer in an electrically conductive manner is arranged, the material of the material element differing from that of the gas-sensitive layer and comprising a metal and/or a metal-containing chemical compound.
US08390032B2	Depletion mode field effect transistor for ESD protection A field effect transistor is provided having a reduced drain capacitance per unit gate width. A gate electrode 21 (G) having a plurality of sides is formed in first-conductivity first semiconductor region 14. Drain region 18D (D) is formed inside the gate electrode, and source regions 18S (S) are formed in respective regions outside the plurality of sides in widths that do not reduce the corresponding channel widths of the drain region. The gate electrode is formed along all the plurality of sides of the drain region in order to form a transistor.
US08390029B2	Semiconductor device for reducing and/or preventing current collapse A semiconductor device includes an undoped GaN layer (103) formed on a substrate (101), an undoped AlGaN layer (104) formed on the undoped GaN layer (103) and having a band gap energy larger than that of the undoped GaN layer (103), a p-type AlGaN layer (105) and a high-concentration p-type GaN layer (106) formed on the undoped AlGaN layer (104), and an n-type AlGaN layer (107) formed on the high-concentration p-type GaN layer (106). A gate electrode (112) which makes ohmic contact with the high-concentration p-type GaN layer (106) is formed on the high-concentration p-type GaN layer (106) in a region thereof exposed through an opening (107a) formed in the n-type AlGaN layer (107).
US08390021B2	Semiconductor light-emitting device, light-emitting module, and illumination device A semiconductor light-emitting device having a substrate on which a semiconductor multilayer film is disposed, the semiconductor multilayer film having a layered structure in which a first conductive layer, a light-emitting layer and a second conductive layer are layered above the substrate from bottom to top in the stated order, and being divided into portions by grooves extending perpendicular to the substrate, each portion having a diode structure and serving as a light-emitting element 12, each light-emitting element 12 having a hole 22 in a central portion thereof in plan view, the hole 22 penetrating through the second conductive layer 18 and the light-emitting layer 16 and reaching the first conductive layer 14, and comprising: a first electrode 24 inserted in the hole 22 and having a columnar shape, one end thereof being connected to the first conductive layer 14 at the bottom of the hole 22, and the other end protruding from an opening of the hole 22; and a second electrode 26 formed on the second conductive layer 18 and having an annular shape surrounding the opening of the hole 22.
US08390015B2	Organic EL element, organic EL display apparatus, and manufacturing method of organic EL element An organic EL element includes a substrate and a light refractive layer, a first transparent electrode layer, an insulation layer, a hole transport layer, and a photosensitive resin layer stacked above the substrate. A luminous function layer is above the hole transport layer in a recess defined by the photosensitive resin layer. A second transparent electrode layer is above the luminous function layer. The light reflective layer, the first transparent electrode layer, the insulation layer, and the hole transport layer are formed above the substrate in a region isolated by the photosensitive resin layer. The photosensitive resin layer comprises a material that absorbs incident light of a predetermined wavelength. The first transparent electrode layer, the insulation layer, the hole transport layer, and the photosensitive resin layer each have a reflectance value that is between a local minimum value and a neighborhood value of the local minimum value.
US08390010B2	Solid state lighting devices with cellular arrays and associated methods of manufacturing Solid state lighting (“SSL”) devices with cellular arrays and associated methods of manufacturing are disclosed herein. In one embodiment, a light emitting diode includes a semiconductor material having a first surface and a second surface opposite the first surface. The semiconductor material has an aperture extending into the semiconductor material from the first surface. The light emitting diode also includes an active region in direct contact with the semiconductor material, and at least a portion of the active region is in the aperture of the semiconductor material.
US08390006B2	Light emitting device including a plurality of GaN-based reflective layers Provided are a light emitting device, a method of manufacturing the light emitting device, a light emitting device package, and a lighting system. The light emitting device includes a reflective layer including a first GaN-based semiconductor layer having a first refractive index, a second GaN-based semiconductor layer having a second refractive index less than the first refractive index, and a third GaN-based semiconductor layer having a third refractive index less than the second refractive index and a light emitting structure layer including a first conductive type semiconductor layer, a second conductive type semiconductor layer, and an active layer disposed between the first conductive type semiconductor layer and the second conductive type semiconductor layer on the reflective layer.
US08390004B2	Light-emitting structure A light-emitting structure includes a p-doped region for injecting holes and an n-doped region for injecting electrons. At least one InGaN quantum well of a first type and at least one InGaN quantum well of a second type are arranged between the n-doped region and the p-doped region. The InGaN quantum well of the second type has a higher indium content than the InGaN quantum well of the first type.
US08390003B2	Electronic element wafer module with reduced warping An electronic element wafer module according to the present invention is provided, in which a translucent support substrate for covering and protecting a plurality of electronic elements is attached on an electronic element wafer having the plurality of electronic elements formed thereon, and an optical filter is formed corresponding to the electronic elements on at least one surface of the translucent support substrate, where the optical filter is removed to lessen warping along a part or all of dicing lines for individually dividing the electronic element wafer module into a plurality of electronic element modules.
US08390001B2	Electronic circuit device A normally-off type silicon carbide junction FET has a problem that the gate thereof is not easy to use due to inferiority in the characteristics of it. This problem occurs because in order to achieve normally-off, the gate voltage should be off at 0V and at the same time, the ON-state gate voltage should be suppressed to about 2.5V to prevent the passage of an electric current through a pn junction between gate and source. Accordingly, a range from the threshold voltage to the ON-state gate voltage is only from about 1 V to 2V and it is difficult to control the gate voltage. Provided in the present invention is an electronic circuit device obtained by coupling, to a gate of a normally-off type silicon carbide junction FET, an element having a capacitance equal to or a little smaller than the gate capacitance of the junction FET.
US08389999B2	Method to reduce dislocation density in silicon using stress A crystalline material structure with reduced dislocation density and method of producing same is provided. The crystalline material structure is annealed at temperatures above the brittle-to-ductile transition temperature of the crystalline material structure. One or more stress elements are formed on the crystalline material structure so as to annihilate dislocations or to move them into less harmful locations.
US08389995B2	Epitaxial solid-state semiconducting heterostructures and method for making same A method for producing a solid-state semiconducting structure, includes steps in which: (i) a monocrystalline substrate is provided; (ii) a monocrystalline oxide layer is formed, by epitaxial growth, on the substrate; (iii) a bonding layer is formed by steps in which: (a) the impurities are removed from the surface of the monocrystalline oxide layer; (b) a semiconducting bonding layer is deposited by slow epitaxial growth; and (iv) a monocrystalline semiconducting layer is formed, by epitaxial growth, on the bonding layer so formed. The solid-state semiconducting heterostructures so obtained are also described.
US08389990B2	Nonvolatile semiconductor memory device and manufacturing method thereof A nonvolatile semiconductor memory device of the present invention includes a substrate (1), first wires (2), memory cells each including a resistance variable element (5) and a portion of a diode element (6), second wires (11) which respectively cross the first wires (2) to be perpendicular to the first wires (2) and each of which contains a remaining portion of the diode element (6), and upper wires (13) formed via an interlayer insulating layer (12), respectively, and the first wires (2) are connected to the upper wires (13) via first contacts (14), respectively, and the second wires (11) are connected to the upper wires (13) via second contacts (15), respectively.
US08389985B2	Color conversion film containing a conjugated high molecular weight copolymer and multicolor light-emitting organic EL device including the same Provided are a color conversion film that maintains sufficient converted light intensity over a long period of time without increasing its thickness and a multicolor light-emitting organic EL device that includes the color conversion film. The color conversion film contains a conjugated high molecular weight copolymer having a structure of formula (1) that has alternating fluorene group-containing repeating units and arylenevinylene repeating units, and has phenylene groups inserted as spacers on both ends of the fluorene groups
US08389982B2	Organic EL element An organic EL element includes an anode and a cathode, and an organic compound layer between the anode and the cathode, the organic compound layer including a light-emitting sublayer, wherein the light-emitting sublayer contains a host, a metal complex acting as a first dopant, and a metal complex acting as a second dopant, the metal complex acting as the first dopant includes an unconjugated ligand and a conjugated ligand, and the first dopant has the lowest excited triplet level originating from the lowest excited triplet level of a unconjugated ligand.
US08389978B2	Two-shelf interconnect Consistent with the present disclosure, a package is provided that includes a housing having a recessed portion to accommodate an integrated circuit or chip. The housing has an inner periphery that defines or delineates the recessed portion. The inner periphery may be stepped and includes first and second surfaces that are spaced vertically from one another and extend in respective parallel planes, for example, to thereby constitute first and second shelves. First bonding pads or contacts (“housing pads”) may be provided on the first surface, which may electrically connect or interconnect with first pads on the integrated circuit (“IC pads”), and second housing pads may be provided on the second surface, which can electrically connect or interconnect with second IC pads. Thus, the IC pads connect to corresponding housing pads on the inner periphery of the housing that are above and below one another. Since the housing pads are not provided on the same surface, the number of housing pads on each step or shelf of the periphery can be reduced, and the housing pads can be spaced from one another by a spacing or pitch that is greater than that of the IC pads. Accordingly, the dimensions and spacing of the housing pads may comply with relevant design rules, while providing connection to an increased number of IC pads.
US08389975B2	Group III nitride semiconductor light-emitting device A Group III nitride semiconductor light-emitting device comprises a substrate (1) and a light-emitting layer (5) having the multiple quantum well structure that comprises barrier layers (5a) and well layers (5b) formed of a gallium-containing Group III nitride semiconductor material provided on the substrate. Each of the well layers constituting the multiple quantum well structure is made of a Group III nitride semiconductor layer to which acceptor impurities are added, and which has thicknesses different from one another and the same conductivity type as that of the barrier layer. The present invention can provide a Group III nitride semiconductor white light-emitting device which can enhance luminous intensity, can obtain high color rendering properties has a simple structure that can be easily formed without fine adjustment of a composition of a phosphor.
US08389971B2	Memory cells having storage elements that share material layers with steering elements and methods of forming the same In some embodiments, a memory cell is provided that includes a storage element formed from an MIM stack including (1) a first conductive layer; (2) an RRS layer formed above the first conductive layer; and (3) a second conductive layer formed above the RRS layer, at least one of the first and second conductive layers comprising a first semiconductor material layer. The memory cell includes a steering element coupled to the storage element, the steering element formed from the first semiconductor material layer of the MIM stack and one or more additional material layers. Numerous other aspects are provided.
US08389969B2	Semiconductor memory using IGBT, insulated gate bipolar transistor, as selective element A semiconductor device includes a semiconductor substrate of a first conductivity type, a first insulating film region that is embedded in a trench formed on the semiconductor substrate, a gate electrode that covers a lower surface of the first insulating film region, and a gate insulating film that is provided between the gate electrode and the semiconductor substrate. The semiconductor device further includes a first diffusion region that covers a first side surface of the first insulating film region, a second diffusion region that covers a second side surface of the first insulating film region, and a third diffusion region that covers an upper surface of the second diffusion region. A selective element includes a field-effect transistor that is constituted by the gate electrode, the first diffusion region, and the second diffusion region, and a bipolar transistor that is constituted by the substrate and the second and third diffusion regions.
US08389968B2	Nonvolatile memory device According to one embodiment, a nonvolatile memory device comprises a plurality of first lines, a plurality of second lines, and memory cells. Each of the memory cells comprise a variable resistor, and a diode. The variable resistor includes a first metal oxide film and is configured to reversibly change resistance value by energy application. The diode includes a second metal oxide film and is connected in series to the variable resistor. The first metal oxide film has at least one of dielectric constant lower than that of the second metal oxide film and physical film thickness greater than that of the second metal oxide film.
US08389967B2	Programmable via devices A device comprises a heater, a dielectric layer, a phase-change element, and a capping layer. The dielectric layer is disposed at least partially on the heater and defines an opening having a lower portion and an upper portion. The phase-change element occupies the lower portion of the opening and is in thermal contact with the heater. The capping layer overlies the phase-change element and occupies the upper portion of the opening. At least a fraction of the phase-change element is operative to change between lower and higher electrical resistance states in response to an application of an electrical signal to the heater.
US08389966B2	Ambient light detecting device for a vehicle A light detecting device includes a case, a reflector, and a light receiving element. The case is fixed to a windshield, and outside light passes through the windshield and an entrance hole defined in the case. A predetermined light travels from a predetermined area, and the reflector reflects the predetermined light of the outside light. The light receiving element is disposed in the case to have a distance from the windshield, and the distance is larger than a distance between the windshield and the entrance hole. The light receiving element receives the reflected predetermined light.
US08389963B2	Laser processing device Provided is a laser processing device capable of preventing laser light from leaking out to the outside of the housing by emitting the laser light to the processing target with the camera detached. The laser processing device includes a laser generator; a scanning optical system for scanning the laser light with respect to a workpiece; a housing frame for accommodating the scanning optical system; a camera for photographing the workpiece, the camera being removably attached to the housing frame and having a light receiving axis branched from an emission axis of the laser light; a camera cover removably attached to the housing frame to cover the camera; a limit SW for detecting detachment of the camera cover from the housing frame; and a laser output control section for prohibiting the emission of the laser light to the workpiece based on a cover detection signal.
US08389962B2	System and method for compensating for magnetic noise A system and method for noise compensation of a charged particle beam location includes one or more sensors that are spaced apart from each other for sensing magnetic noises within at least one predefined frequency band thereby to provide magnetic noise measurements with synchronous detection of the location of a charged particle beam. Based on the magnetic noise measurements and on relationships between values of the magnetic noises and particle beam location errors, magnetic noise compensations signals are generated. An object is then scanned by a particle beam in response to a desired particle beam scan pattern and the magnetic noise compensation signals.
US08389954B2	System for fast ions generation and a method thereof The present invention discloses a system and method for generating a beam of fast ions. The system comprising: a target substrate having a patterned surface, a pattern comprising nanoscale pattern features oriented substantially uniformly along a common axis; and; a beam unit adapted for receiving a high power coherent electromagnetic radiation beam and focusing it onto said patterned surface of the target substrate to cause interaction between said radiation beam and said substrate enabling creation of fast ions.
US08389953B2	Focused ion beam apparatus A focused ion beam apparatus includes an ion gun unit having an emitter tip, a gas supply unit that supplies gas to the tip, and an ion source gas supply source. An extracting electrode ionizes the gas adsorbed onto the surface of the tip and extracts ions by applying a voltage between the extracting electrode and the tip. A cathode electrode accelerates the ions toward a sample. An aperture member has an opening that passes therethrough a part of the ion beam ejected from the ion gun unit, and a lens system focuses the ion beam onto the sample.
US08389950B2	High performance micro-fabricated quadrupole lens This invention provides a method of aligning sets of cylindrical electrodes in the geometry of a miniature quadrupole electrostatic lens, which can act as a mass filter in a quadrupole mass spectrometer. The electrodes are mounted in pairs on microfabricated supports, which are formed from conducting parts on an insulating substrate. Complete segmentation of the conducting parts provides low capacitative coupling between co-planar cylindrical electrodes, and allows incorporation of a Brubaker prefilter to improve sensitivity at a given mass resolution. A complete quadrupole is constructed from two such supports, which are spaced apart by further conducting spacers. The spacers are continued around the electrodes to provide a conducting screen.
US08389948B2	Aharonov-bohm sensor An Aharonov-Bohm (AB) sensor is provided. The AB sensor includes a beam splitter configured to split a first electron beam into a first wave and a second wave. The beam splitter is configured to direct the first wave along a first path through a field-free cage. A phase of the first wave is configured to shift in response to a vector potential of a signal. The vector potential is present within the field-free cage. The AB sensor includes a beam combiner configured to combine the phase shifted first wave with the second wave to generate a second electron beam, which is modulated based on the phase shift of the first wave. The AB sensor includes a detector configured to receive the second electron beam and to detect the signal based on the modulation of the second electron beam.
US08389946B2	Plasma panel based ionizing radiation detector A radiation detector is formed from a plasma panel that includes a front substrate, and a back substrate that forms a generally parallel gap with the front substrate. X (column) and Y (row) electrodes are coupled by gas discharge events to define one or more pixels. Impedances are coupled to the X and Y electrodes, and a power supply is coupled to one or both types of electrodes. Discharge event detectors are coupled to the impedances.
US08389945B1	Object detecting system in imaging-based barcode readers An apparatus for capturing images of a target object having a barcode. The apparatus includes a reflector, an LED emitting mostly invisible light, and a photodetector. The LED is configured to emit a first portion of the invisible light toward the target object directly and to emit a second portion of the invisible light toward the reflector. The reflector is configured to redirect at least some of the second portion of the invisible light toward the target object. The photodetector is configured to detect returned invisible light from the target object to generate an electrical signal.
US08389940B2	Discriminating molecule family for neutron and gamma radiation The invention relates to a novel discriminating molecule family for neutron and gamma radiation, and to the preparation method thereof. Said molecules are also useful for detecting radiation (X, gamma, electrons, protons, ions), and thus for manufacturing radar, and industrial or medical dosimetry instruments.
US08389939B1	System and method of dual energy radiation detection A system and method for providing an apparatus for detecting radiance at a plurality of wavelengths is disclosed. The system and method includes an arrayed pixel sensor with a plurality of sub-pixel sections including a first sub-pixel section configured to detect radiance received from a radiating body at a first wavelength and a second sub-pixel section configured to detect radiance received from the radiating body at a second wavelength. The system and method also determines a ratio of the radiance detected at the first wavelength and the radiance detected at the second wavelength to determine a temperature of the radiating body based on the ratio.
US08389927B2	Optical arrangement and its use An optical arrangement has a laser configured to emit a laser beam, an amplitude mask and a focusing element. The amplitude mask is disposed between the laser and the focusing element in a path of the laser beam such that the laser beam hits the amplitude mask before being modified by the focusing element so as to direct the laser beam to a focal point within a photosensitive material.
US08389925B2	Optical encoder device comprising a moveable slit plate and a stationary slit plate An optical encoder device is provided, in which the number of light transmissive slits of a stationary slit plate can be increased as much as possible according to the length of a light receiving surface of a light receiving element to produce an output signal with little distortion. A movable slit plate 3 includes a slit row R1 in which a plurality of light transmissive slits (light transmissive portions) S1 each having a slit width of 180° in terms of electrical angle and a plurality of light non-transmissive slits (light non-transmissive portions) S2 each having a slit width of 180° in terms of electrical angle are alternately formed. A stationary slit plate 4 includes a slit row R2 in which a plurality of light transmissive slits S3 each having a slit width of 180° in terms of electrical angle and a plurality of light non-transmissive slits S4 each having a slit width of (360Xk-180)° in terms of electrical angle are alternately formed. k is a value that satisfies k=1±(⅓n) where n denotes the number of the light transmissive slits S3.
US08389922B2	Sensing Devices and Manufacturing Methods Therefor A sensing device is provided. The sensing device includes a sensing pixel array and a memory unit. The sensing pixel array is formed in a substrate and includes a plurality of pixels for sensing light. The substrate has a first side and a second side opposite to the first side and receives the light through the first side for sensing the light. The memory unit is formed on the second side of the substrate for memorization.
US08389919B2	Laser safety controller A laser controller may operate a laser at a high power level, such as Class 3R, Class 3B, or higher, but may have safety interlocks to limit exposure to a safe level and may, as a system, be classified as Class 1. The laser controller may control a laser that transmits a light beam to a sensor, and may operate the laser in a high power mode when the sensor senses the light beam. While a laser is transmitting and the laser beam is not sensed, the laser may be operated within Class 1 power levels. When the light beam is broken, the laser controller may turn off the laser or change the power level to a safe level such that a person would not be exposed to any more energy than a Class 1 level. The laser controller may use various mechanisms to set a detection threshold and may use an ambient light sensor to determine when detection may be impossible.
US08389916B2	Electromagnetic heating An apparatus for applying RF energy to an object, including at least one slower-scanning, frequency source and at least one faster-scanning frequency source, and a controller which sweeps a range of frequencies using the faster-scanning source to measure RF absorption and controls the slower-scanning frequency source based on the sweep.
US08389912B2	Induction cooker There is provided an induction cooker capable of detecting failures in an infrared ray sensor with excellent accuracy. The induction cooker includes an infrared-ray detection unit (6) which includes an infrared-ray incidence section (6a) to detect an infrared ray entering the infrared-ray incidence section, the infrared ray being radiated from a bottom surface of a pan, passing through a top plate, and entering the infrared-ray incidence section; a infrared-ray temperature calculation unit (7) operable to calculate a temperature of the bottom surface of the pan based on an output of the infrared-ray detection unit; a light emitting unit (8) which is provided below the top plate and emits light with a first luminance for indicating a position of the infrared-ray incidence section (6a); and a failure detection unit (9) operable to detect failures in the infrared-ray detection unit based on an amount of a change of an output of the infrared-ray temperature calculation unit which is based on an output of the light emitting unit. The failure detection unit (9) controls the light emitting unit to emit light with a second luminance higher than the first luminance and detects failures in the infrared-ray detection unit based on whether or not an amount of an increase in the output of the temperature calculation unit falls within a predetermined range.
US08389911B2	Electromagnetic induction type heating device, hot air generating device and electrical power generating device Permanent magnets are arranged at the interior of a rotating body at uniform intervals. The device comprises: a rotating body which is rotated by a motor; a heat generation part, which is disposed in the vicinity of the rotating body, which includes an electroconductive material, and which is disposed within the magnetic fields of the permanent magnets; and a hot air capture plate, which is disposed in the vicinity of the heat generation part, and in which a plurality of hot air flow passage holes are provided, the rotating body being rotated by a rotating shaft, which is coupled to the motor. Furthermore, a thermocouple may be connected to the heat generation part, and the heat energy that would be dissipated to the outside air is converted to electrical energy by the thermocouple. Furthermore, the electromagnetic induction device is constituted such that a hot air capture plate, in which a plurality of hot air flow passage holes are provided, is disposed in the vicinity of the heat generation part.
US08389909B2	Heating device having electric and fuel powered heat sources A portable device which generates heat and which can be used alternatively as a corded, plug-in device or as a cordless, fuel-powered device. The device has dual heating capabilities—each of which is powered by a unique cartridge. For use as a plug-in device an electric cartridge that connects the device to an adapter is utilized, whereas for use as a portable device a fuel cartridge is utilized for supplying a hydrocarbon fuel to support combustion. Use of one of the cartridges prevents the use of the other.
US08389907B2	Heating element arrangement for baker's oven A baking oven 10 comprising an oven chamber 11, heating elements 20, 120 for generating heat, a support 14, 114A for supporting one or more baking trays 30 in a baking tray position within the heating chamber 11. The oven has an active region 120 under the baking tray position and an inactive region 130 positioned outwardly of the active region 120, the heating elements 20 being positioned to provide substantially more heat to the active region 120 than to the inactive region 130 for more directly heating an underside of the baking tray position. The oven chamber 11 may also include second support 114B within the oven chamber for supporting one or more baking trays above the baking trays on the first support 14 and second heating elements 127 intermediate the first support and a second support for supplying heat to an underside of the baking trays on the second support 114B; the second support 114B being movable relative to the second heating elements 127 and coaxial with the first support 20, 114A.
US08389899B2	Connector for connecting welding torch A connector for connecting a welding torch, where the connector body and the house are made of insulating material and designed as a unit in one piece connected by a rear wall. The connector includes an insert made of electrically conductive material carrying a threaded surface made of electrically conductive material and a contact surface. The insert can be fitted in a nest formed by a side surface of the connector body part and a surface of the house part opposite to the side surface. An opening on the sidewall of the house part provides access to the side surface of the insert for connecting the side surface to a current, and the insert is secured rotationally in the nest.
US08389879B2	Detection device and method for detecting occupancy of a seat using a light guide force sensor To allow more reliable detection of occupancy of a seat by a person, the invention includes a detection device for detecting occupancy of a seat, in particular of a vehicle seat or motor vehicle seat, comprising at least one elongate light guide having at least one elongate core element and at least one elongate sheath at a distance from the core element. The light guide is deformable by mechanical actuation means in at least one direction running perpendicular to the longitudinal axis of the light guide by the deformation brought about by the seat being occupied causes the light to exit from the light guide on the side opposite the mechanical means.
US08389872B2	Electrode structure adapted for high applied voltage and fabrication method thereof An electrode structure adapted for high applied voltage is provided, which comprises a conductive plate substrate and a covering layer disposed thereon such that a covering percentage of the covering layer over the conductive plate substrate is more than 50%. Since area of the conductive plate substrate covered by the covering layer is larger than the area exposed, the possibility of arcing is reduced and the breakdown voltage applied to the electrode structure may be increased.
US08389868B2	Packaged integrated circuits having inductors and methods to form inductors in packaged integrated circuits Packaged integrated circuits having inductors and methods to form inductors in packaged integrated circuits are disclosed. An example method comprises forming a substrate having a first trace and a contact, attaching an integrated circuit to the substrate over the first trace, and electrically coupling the first trace to the contact via an electrical conductor that extends over the integrated circuit to form the inductor in the packaged integrated circuit.
US08389867B2	Multilayered circuit substrate with semiconductor device incorporated therein For the purpose of providing a semiconductor element built-in type multilayered circuit board in which a semiconductor element is closely joined to a recess of an insulating substrate to effectively disperse heat generated from the semiconductor element through the insulating substrate at a working temperature region of the semiconductor element circuit board, to surely conduct an electrical connection of an electronic part such as semiconductor element or the like in a short wiring and to enable the high density mounting of semiconductor elements, miniaturization and increase of working speed, there is proposed a semiconductor element built-in type multilayered circuit board formed by laminating a plurality of semiconductor element built-in type boards each comprising an insulating substrate and a semiconductor element accommodated in a recess formed therein, characterized in that a difference between a linear expansion coefficient of the insulating substrate and a linear expansion coefficient of the semiconductor element in a temperature zone of 20-300° C. is less than 1×10−5/K.
US08389863B2	Flat display panel A flat display panel is disclosed. In one embodiment, the flat display panel includes i) a first substrate on which a display unit is formed, ii) a second substrate formed to face the first substrate, iii) a resin layer formed on the second substrate; a window formed on the resin layer, iv) a flexible printed circuit (FPC) and a spacer formed between the window and the first end of the FPC. A first end of the FPC is combined with the second substrate, and a second end of the FPC is combined with the first substrate, so that the first substrate and the second substrate are electrically connected to each other.
US08389860B2	Bonding wire for semiconductor devices A bonding wire for semiconductor devices includes a core member formed of an electrically-conductive metal, and a skin layer mainly composed of a face-centered cubic metal different from the core member and formed thereon. An orientation ratio of <100> orientations in crystalline orientations in a wire lengthwise direction at a crystal face of a surface of the skin layer is greater than or equal to 50%, and the <100> orientations have an angular difference relative to the wire lengthwise direction. The angular difference is within 15 degrees.
US08389856B2	Waterproof structure of electrical junction box There is provided a waterproof structure for the electrical junction box includes a stepwise portion in which a punched hole has to be provided for molding a locking projection on a peripheral wall of a main-body case. The waterproof structure prevents intrusion of a droplet from an outside into the main-body case via the punched hole and thereby improves waterproof performance. An extended portion 37d is provided on a left wall portion 22 of the main-body case 2 for moving the position of the punched hole which should be provided in the stepwise portion 35 toward the side of the locking projection 33. A hole-sealing portion 47a is provided at a edge portion 42a of the left wall portion 42 of the cover 4, the hole-sealing portion 47a is configured to cover the entire opening of the punched hole 37 moved toward the side of the locking projection 33 in a state where the cover is attached to the main-body case 2.
US08389855B2	Recessed signal-receiver mounting system for a building structure and associated methods A system for mounting a pair of signal-receiving devices recessed within a building surface includes a base housing having an inner chamber and positionable behind a building surface and/or furniture surface. A front has a first opening, and a wall has a second and third opening. A secondary housing is positionable adjacent the base housing and has an interior space. A first aperture is positionable in communication with the second opening. A second aperture is positioned in spaced relation from the base housing's wall. A first signal receiver is positionable within the interior space and is connectable to a first signal carrier. A second signal receiver is positionable within the inner chamber and has a second connector positionable adjacent the third opening and connectable to a second signal carrier. A base housing cover plate is positioned to cover at least a part of the base housing first opening.
US08389853B2	Asphaltene based photovoltaic devices Photovoltaic devices and methods of making the same, are disclosed herein. The cell comprises: a first electrically conductive layer; at least one photoelectrochemical layer comprising metal-oxide particles, an electrolyte solution, an asphaltene dye, and a second electrically conductive layer.
US08389852B2	Electrode structure for use in electronic device and method of making same An electrode structure is provided for use in an electronic device. In certain example embodiments, an electrode structure includes a supporting glass substrate (e.g., soda-lime silica based float glass), a buffer layer (e.g., SixNy), and a conductive electrode (e.g., Mo) provided in this order. The buffer layer is advantageous in that it prevents or reduces sodium (Na) migration from the glass substrate into semiconductor layer(s) of the electronic device.
US08389849B2	Solar battery panel A solar battery panel wherein cracking of solar battery cells can be reduced without reducing the power generating capacity per unit area. The solar battery panel consists of a plurality of solar battery cells (1) connected in series by connecting surface electrode tabs (104) to rear electrode tabs (105). In the solar battery panel, a tab-to-tab connecting portion (107) and a tab-to-cell connecting portion (106) are arranged via a gap (108) in the solar battery cell arrangement direction (162) without these portions overlapping each other. One end portion (107a) of the tab-to-tab connecting portion (107) exists within a region of a non-light receiving surface (3).
US08389847B2	Piano with electronic tone generator A piano with an electronic tone generator capable of outputting musical sound signals of a reverberation and/or a resonance, in accordance with whether an external output is performed or not.
US08389844B2	Tone generation apparatus In response to detection of a note-on instruction, a CPU assigns a tone generating unit comprising two tone generating channels and sets tone color control data of the assigned tone generating unit into tone generator registers. The tone color control data includes a parameter common to the two channels. Once the CPU gives a tone generation start instruction to a tone generator, the tone generator accumulates a frequency number common to the two channels to thereby generate a progressive phase common to the two channels. Waveform readout section reads out left-channel and right-channel waveform data from a waveform memory on the basis of the phase and waveform selecting information of the left and right channels. Tone characteristics of the read-out left- and right-channel waveform data are controlled by a characteristic control section on the basis of a characteristic control parameter common to the two channels.
US08389840B2	Piccolo A piccolo includes a cylindrical headjoint with an embouchure, a stopper including an adjustable seal disposed in a free end of the cylindrical headjoint, and a conical body having tone holes. The tone holes include a single tone hole corresponding to c2 and an end tone hole at a free end of the conical body. The end tone hole is lower than the note d1 and extends at least to the note c1.
US08389838B2	Guitar pick holder ornament A guitar pick holder with a recessed rim and a rear support plate for receiving and securing guitar picks. A fastener or a hoop for accepting a material provides means for the guitar pick to be ornamentation. An opening in the holder allows visibility to the guitar pick when the guitar pick is placed in the holder ornament.
US08389835B2	Sound system in a stringed musical instrument A sound system producing characteristic sounds from an acoustic instrument is provided. The sound system may include a stringed musical instrument and an electronic audio subsystem. The stringed musical instrument may include a neck extending away from a body toward a head. A plurality of strings may be stretched from a bridge on the body to the head at a terminal end of the neck. The bridge may be coupled to a soundboard and operable for connecting the plurality of strings to the body. The electronic audio subsystem may include at least one distributed mode loudspeaker. The distributed mode loudspeaker may be attached to the soundboard of the stringed musical instrument. The distributed mode loudspeaker may induce uniformly distributed vibration modes in the soundboard. A power amplification device may be disposed inside the body of the stringed musical instrument to provide power to the distributed mode loudspeaker.
US08389833B2	Upright piano type action An upright piano type action has a wippen 30, a jack 40, a butt 5, a swinging shank (hammer shank 71), a swinging member (hammer 70), a catcher shank 53, a backcheck 60 and a catcher 52. To any of the moving members, namely the butt 5, the swinging shank (hammer shank 71), the swinging member (hammer 70), the catcher 52 and the catcher shank 53, a weight 110, 120, 130 or 140 is attached. The weights 110, 120, 130, 140 are placed to apply loads, respectively, in a state where a key is not being depressed, in a direction opposite to a direction in which the moving members swing for hitting.
US08389831B2	Wheat variety 25R30 A wheat variety designated 25R30, the plants and seeds of wheat variety 25R30, methods for producing a wheat plant produced by crossing the variety 25R30 with another wheat plant, and hybrid wheat seeds and plants produced by crossing the variety 25R30 with another wheat line or plant, and the creation of variants by mutagenesis or transformation of variety 25R30. This invention also relates to methods for producing other wheat varieties or breeding lines derived from wheat variety 25R30 and to wheat varieties or breeding lines produced by those methods.
US08389829B1	Maize variety hybrid X8F936 A novel maize variety designated X8F936 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X8F936 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X8F936 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X8F936, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X8F936. This invention further relates to methods for producing maize varieties derived from maize variety X8F936.
US08389828B1	Maize variety hybrid X8R681 A novel maize variety designated X8R681 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X8R681 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X8R681 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X8R681, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X8R681. This invention further relates to methods for producing maize varieties derived from maize variety X8R681.
US08389822B1	Maize variety hybrid X95A930 A novel maize variety designated X95A930 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X95A930 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X95A930 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X95A930, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X95A930. This invention further relates to methods for producing maize varieties derived from maize variety X95A930.
US08389816B1	Soybean cultivar 02062556 A soybean cultivar designated 02062556 is disclosed. The invention relates to the seeds of soybean cultivar 02062556, to the plants of soybean cultivar 02062556, to the plant parts of soybean cultivar 02062556, and to methods for producing progeny of soybean cultivar 02062556. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 02062556. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 02062556, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 02062556 with another soybean cultivar.
US08389815B2	Soybean variety A1023761 The invention relates to the soybean variety designated A1023761. Provided by the invention are the seeds, plants and derivatives of the soybean variety A1023761. Also provided by the invention are tissue cultures of the soybean variety A1023761 and the plants regenerated therefrom. Still further provided by the invention are methods for producing soybean plants by crossing the soybean variety A1023761 with itself or another soybean variety and plants produced by such methods.
US08389814B2	Soybean cultiyar 2252921658 A soybean cultivar designated 2252921658 is disclosed. The invention relates to the seeds of soybean cultivar 2252921658, to the plants of soybean 2252921658, to plant parts of soybean cultivar 2252921658, and to methods for producing a soybean plant produced by crossing soybean cultivar 2252921658 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars, or breeding cultivars, and plant parts derived from soybean variety 2252921658, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar 2252921658, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing the cultivar 2252921658 with another soybean cultivar.
US08389805B2	Promoter, promoter control elements, and combinations, and uses thereof The present invention is directed to promoter sequences and promoter control elements, polynucleotide constructs comprising the promoters and control elements, and methods of identifying the promoters, control elements, or fragments thereof. The invention further relates to the use of the present promoters or promoter control elements to modulate transcript levels.
US08389802B2	Artificial chromosomes, uses thereof and methods for preparing artificial chromosomes Methods for amplification of nucleic acids in cells are provided. Also provided are cells that contain the nucleic acids.
US08389798B2	Method to identify disease resistant quantitative trait loci in soybean and compositions thereof The present invention is in the field of plant breeding and genetics, particularly as it pertains to the genus, Glycine. More specifically, the invention relates to a method for screening soybean plants containing one or more quantitative trait loci for disease resistance, species of Glycine having such loci and methods for breeding for and screening of Glycine with such loci. The invention further relates to the use of exotic germplasm in a breeding program.
US08389796B1	Maize variety hybrid X00A016 A novel maize variety designated X00A016 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X00A016 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X00A016 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X00A016, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X00A016. This invention further relates to methods for producing maize varieties derived from maize variety X00A016.
US08389795B2	Vectors and methods for the mutagenesis of mammalian genes Disclosed herein are methods for mutagenizing a mammalian gene, the methods involving introducing into a mammalian cell a retroviral vector which includes a splice acceptor sequence, a transcription termination sequence, and retroviral packaging and integration sequences, the introducing step being carried out under conditions which allow the vector to integrate into the genome of the cell. Also disclosed are retroviral vectors for use in these methods as well as methods for the use of mutagenized cells.
US08389794B2	Transgenic pig as a model of Alzheimer's disease The present invention relates to a modified pig as a model for studying Alzheimer's disease. The modified pig model displays one or more phenotypes associated with Alzheimer's disease. Disclosed is also a modified pig comprising a modified human and/or porcine APP gene, and/or PS1 gene, and/or a transcriptional and/or translational product or part thereof. The invention further relates to methods for producing the modified pig; and methods for evaluating the effect of a therapeutical treatment of Alzheimer's disease; methods for screening the efficacy of a pharmaceutical composition; and a method for treatment of a human being suffering from Alzheimer's disease are disclosed.
US08389790B2	Process for isomerisation of lycopene in the presence of thiourea The present invention relates to isomerization of Z-lycopene in mixtures of isomers to mixtures enriched with all E-lycopene.
US08389788B2	Olefin metathesis reactant ratios used with tungsten hydride catalysts Processes for olefin metathesis, for example for the production of propylene, utilize a catalyst comprising a solid support and a tungsten hydride bonded to alumina present in the support. Conversion, selectivity, and/or catalyst stability advantages may be realized when a first olefin reactant (e.g., ethylene) is present in the hydrocarbon feedstock at a stoichiometric deficit relative to a second, higher carbon number olefin reactant (e.g., butylene).
US08389787B1	Control of 2-phenyl content in alkylbenzenes during production A process is presented for the management and control of the 2-phenyl content in a benzene alkylation process. The process includes the use of multiple reactor beds, with benzene flowing through the reactor beds in a sequential manner. The olefin stream is split to two or more portions, and a separate portion is passed to the first reactor bed and second reactor bed. Control of the ratio of the olefin flow splits controls the 2-phenyl content.
US08389777B2	Continuous method for making chlorhydrines Continuous process for producing a chlorohydrin, wherein a polyhydroxylated aliphatic hydrocarbon, an ester of a polyhydroxylated aliphatic hydrocarbon or a mixture thereof is reacted with a chlorinating agent and an organic acid in a liquid reaction medium whose steady-state composition comprises the polyhydroxylated aliphatic hydrocarbon and esters of the polyhydroxylated aliphatic hydrocarbon whose sum content, expressed as moles of polyhydroxylated aliphatic hydrocarbon, is greater than 1.1 mol % and less than or equal to 30 mol %, the percentage being based on the organic part of the liquid reaction medium.
US08389776B2	Treatment of phenol A process for the removal of by-products from a phenolic mixture, which process may include the following steps: subjecting a phenolic mixture to extractive distillation to produce an initial phenolic mixture, contacting the initial phenolic mixture containing phenol and one or more by products with a catalyst to produce a first purified phenol product mixture, and distilling the first purified phenol product mixture to produce a second purified phenol product mixture; wherein the extractive distillation is carried out in two columns, a higher pressure column and a lower pressure column.
US08389775B2	Process for preparing polyether alcohols The invention relates to a process for preparing polyether alcohols, which comprises the steps a) reaction of an unsaturated natural oil or fat with a mixture of carbon monoxide and hydrogen, b) reaction of the mixture from step a) with hydrogen, c) reaction of the product from step b) with an alkylene oxide in the presence of a catalyst.
US08389774B2	Parallelized jet loop reactors The invention relates to a device and a method for the continuous reaction of a liquid and a second fluid, wherein the device comprises at least two jet loop reactors interconnected in parallel and common outer liquid recirculation.
US08389771B2	Alkynyl phenyl derivative compounds for treating ophthalmic diseases and disorders Provided are alkynyl phenyl derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.
US08389770B2	Method for producing diaminodiphenyl alkanes The invention relates to a method for producing diaminodiphenyl alkanes, wherein an aromatic amine, which can be substituted or unsubstituted, is reacted with a C1-C3 aldehyde in the presence of a heterogeneous catalyst, said catalyst being a mesoporous acidic ion exchanger based on a divinylbenzene/styrene copolymer and the catalyst having acid centers in a concentration of 4 to 6 eq/kg as measured according to DIN 54 403 and the average pore diameter of the catalyst particles being 10 to 32 nm as measured according to ASTM D 4222 10, and the content of polynuclear compounds in the reaction mixture being ≦10% by weight.
US08389769B2	Polymerizable type II photoinitiators and curable compositions A polymerizable Type II photoinitiator according to Formula (I): wherein: A represents a Norrish Type II initiating group; L represents a divalent linking group positioning the Norrish Type II initiating group A and the CR2R3-group in a 1-5 to a 1-8 position wherein position 1 is defined as the first atom in the aromatic or alicyclic ring of A to which L is covalently bonded and the position 5 to 8 is defined as the carbon atom of the CR2R3-group to which L is covalently bonded, with the proviso that L does not contain an amine. Radiation curable compositions and inks include the multifunctional Type II photoinitiator.
US08389768B2	Methods and compositions comprising novel cationic lipids Provided herein are novel cationic lipids, compositions comprising the cationic lipids, and methods of using the cationic lipids. In some claims, the cationic lipids have cytotoxic activity and can be used alone or in combination with a cytotoxic bioactive compound to kill a cell. In some of these claims, the cationic lipid enhances the cytotoxic activity of the cytotoxic bioactive compound. Methods for treating a subject afflicted with a disease or unwanted condition are provided, wherein the method comprises administering a delivery system comprising a novel cationic lipid to the subject. The invention further provides methods for making delivery systems comprising the novel cationic lipids of the invention.
US08389766B2	Insecticidal compounds A compound of formula (I): wherein A1, A2, A3, A4, R1, R2, G1, G2, Q1 and Q2 are as defined in claim 1; or a salt or N-oxide thereof. Furthermore, the present invention relates to processes and intermediates for preparing compounds of formula (I), to insecticidal, acaricidal, molluscicidal and nematicidal compositions comprising them and to methods of using them to combat and control insect, acarine, mollusc and nematode pests.
US08389755B2	Gas adsorption material, precursor of same, and method of producing gas adsorption material A gas adsorption material has a three-dimensional structure wherein a ligand (p-hydroxybenzoic acid) having an aromatic ring as a principal skeleton containing, a carboxyl group and a functional group capable of forming a coordinate bond, the functional group being other than the carboxyl group, and a metal nucleus (Zn) are bonded to each other at a ratio of 1:1. The ligand contains a functional hydroxyl group other than the carboxyl group, and the carboxyl group and the functional group other than the carboxyl group are bonded in at least one position to the metal nucleus. The gas adsorption material is produced by drying a precursor obtained by reacting the ligand and the metal nucleus, dissolving the dried precursor in an organic solvent, heating and stirring a resultant solution to form a three-dimensional structure that includes the organic solvent as a crystal solvent, and removing the crystal solvent.
US08389750B2	Purification of propylene oxide The invention is a method of purifying propylene oxide containing acetone, water, methanol, methyl formate, aldehydes, and hydrocarbons impurities. The method comprises contacting the propylene oxide with a glycol and a C7 or greater alkane in a liquid/liquid solvent extraction, and separating propylene oxide having reduced impurities content. The purified propylene oxide may be produced by reacting propylene and a hydroperoxide to produce a crude propylene oxide effluent, distilling the crude effluent to produce a propylene oxide stream which contains 1-5 weight percent of the impurities, contacting the propylene oxide stream with a glycol and a C7 or greater alkane in a liquid/liquid solvent extraction, then separating an alkane fraction comprising propylene oxide from a glycol fraction, and distilling the alkane fraction in one or more steps to produce an alkane bottoms stream and a propylene oxide product having less than 0.1 weight percent impurities.
US08389746B2	Cyclic carbonyl compounds with pendant carbonate groups, preparations thereof, and polymers therefrom A one pot method of preparing cyclic carbonyl compounds comprising an active pendant pentafluorophenyl carbonate group is disclosed. The cyclic carbonyl compounds can be polymerized by ring opening methods to form ROP polymers comprising repeat units comprising a side chain pentafluorophenyl carbonate group. Using a suitable nucleophile, the pendant pentafluorophenyl carbonate group can be selectively transformed into a variety of other functional groups before or after the ring opening polymerization.
US08389743B2	Histamine-3 receptor antagonists This invention is directed to a compound of formula I, wherein R1, R2, R4, R5, R6, R7, R8 and n are as defined herein, or a pharmaceutically acceptable salt thereof; a pharmaceutical composition containing a compound of formula I, a process of preparation of a compound of formula I, a method of treatment of a disorder or condition such as depression, mood disorders, schizophrenia, anxiety disorders, Alzheimer's disease, attention-deficit hyperactivity disorder (ADHD), psychotic disorders, cognitive disorders, sleep disorders, obesity, dizziness, epilepsy, motion sickness, respiratory diseases, allergy, allergy-induced airway responses, allergic rhinitis, nasal congestion, allergic congestion, congestion, hypotension, cardiovascular disease, diseases of the GI tract, hyper and hypo motility and acidic secretion of the gastro-intestinal tract that may be treated by antagonizing histamine H3 receptors, the method comprising administering to a mammal in need of such treatment a compound of formula I as described above.
US08389741B2	Difluoroboradiazaindacene dyes The invention relates to difluoroboradiazaindacene dyes of the formula (1) where R1=fluoro-substituted phenyl residue C6HmFn where n=1 to 5 and m+n=5; or fluoro-substituted naphthyl residue C10HmFn where n=1 to 9 and m+n=9; R2=CH3, C2H5, C3H7, or C4H9; R3=alkyl, aryl, or vinyl aryl; R4, R5=H, F, or an R4 and R5 bridging residue CH═CH—CH═CH; R6, R7=H, F, or an R6 and R7 bridging residue CH═CH—CH═CH; and R8=alkyl or aryl.
US08389740B2	Process for preparing ionic liquids by anion exchange Process for preparing salts of the formula I (B+)nxAy− where B is a cation comprising at least one nitrogen atom, A is an anion and n is an integer from 1 to 3, x and y are each an integer from 1 to 3 and the product of x and y is equal to n, by reacting salts of the formula II (B+)nxCy− where B and n, x and y are as defined above and C is a compound which has one or more carboxylate groups (referred to as carboxylate for short) and is different from A, with the ammonium salt of the anion A or with the protic acid of the anion A in the presence of ammonia.
US08389737B2	Furo[3, 2-B] pyrrol-3-ones as cathespin S inhibitors A first aspect of the invention relates to a compound of formula (I), or a pharmaceutically acceptable salt, hydrate, complex or pro-drug thereof, wherein: one of R3 and R4 is H, and the other is selected from C1-6-alkyl, C1-6-haloalkyl, C1-6-alkoxy, and C6-12-aralkyl; or R3 and R4 are each independently selected from C1-6-alkyl and halo; R9 is a substituted 5 or 6-membered aryl or heteroaryl group or a 6,5- or 6,6-fused biaryl or heterobiaryl group. Compounds of formula (I) exhibit surprisingly high efficacies for human cathepsin S, excellent selectivity verses other mammalian cathepsins and are useful for treatment of diseases such as rheumatoid arthritis, multiple sclerosis, myasthenia gravis, transplant rejection, diabetes, Sjogrens syndrome, Grave's disease, systemic lupus erythematosis, osteoarthritis, psoriasis, idiopathic thrombocytopenic purpura, allergic rhinitis, asthma, atherosclerosis, obesity, chronic obstructive pulmonary disease and chronic pain.
US08389730B2	Compositions and methods for the treatment of disease associated with TRP-P8 expression Provided are small-molecule Trp-p8 modulators, including Trp-p8 agonists and Trp-p8 antagonists, and compositions comprising small-molecule Trp-p8 agonists as well as methods for identifying and characterizing novel small-molecule Trp-p8 modulators and methods for decreasing viability and/or inhibiting growth of Trp-p8 expressing cells, methods for activating Trp-p8-mediated cation influx, methods for stimulating apoptosis and/or necrosis, and related methods for the treatment of diseases, including cancers such as lung, breast, colon, and/or prostate cancers as well as other diseases, such as benign prostatic hyperplasia, that are associated with Trp-p8 expression.
US08389727B2	Solid forms of N-(4-(7-Azabicyclo[2.2.1]Heptan-7-yl)-2-Trifluoromethyl)Phenyl)-4-Oxo-5-(Trifluoromethyl)-1,4-Dihydroquinoline-3-Carboxamide The present invention relates to substantially crystalline and solid state forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide (Form A-HCl, Form B, Form B-HCl, or any combination of these forms), pharmaceutical compositions thereof, and methods of treatment therewith.
US08389726B2	Metal coordinated compositions A metal coordination complex of a biologically active moiety and a metal is disclosed. The complex confers to the biologically active moiety an improved performance which can include potency, stability, absorbability, targeted delivery, and combinations thereof.
US08389725B2	Tridentate platinum (II) complexes A platinum (II) complex of general formula (II) in which Ar1, Ar2, and Ar3 are each independently aryl, heteroaryl, or heterocyclic. Ar1, Ar2, and Ar3 together form a tridentate ligand coordinated to the platinum through atoms X, Y, and Z, respectively, and X, Y, and Z are independently carbon or nitrogen. V is a bridging group, and W is an anion. The complexes emit in the UV to near IR range and are useful as emitters for organic light emitting devices.
US08389720B2	Quinolone neuropeptide S receptor antagonists The present invention is directed to quinolone compounds which are antagonists of neuropeptide S receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which the neuropeptide S receptor is involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the neuropeptide S receptor is involved.
US08389717B2	Modulators for amyloid beta The invention relates to compounds of formula wherein R1, R2, R3, R4, and Ar are as defined in the specification and claims, or to pharmaceutically active acid addition salts of such compounds. Compounds of formula I are modulators for amyloid beta and may be useful for the treatment or prevention of a disease associated with the deposition of β-amyloid in the brain, in particular Alzheimer's disease, and other diseases such as cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica and Down syndrome.
US08389713B2	Polysaccharide pseudo-sponge A photocrosslinked polysaccharide pseudo-sponge exhibiting a low swelling property and a high degradation ability in vivo while retaining a suitable strength. The polysaccharide pseudo-sponge is produced by a crosslinking reaction of a photoreactive polysaccharide obtained by introducing a photoreactive group into a polysaccharide, and exhibits a low swelling property and a blue dextran-low dyeaffinity.
US08389711B2	Pharmaceutical composition for treatment of cancer and asthma Provided is a pharmaceutical composition for treating cancer and asthma.The object can be solved by a pharmaceutical composition comprising a siRNA molecule that directs cleavage of mRNA of mucin subtype 5 AC via RNA interference, or an antibody against mucin subtype 5AC as an active ingredient. According to the pharmaceutical composition of the present invention, diseases involving an overexpression of mucin subtype 5 AC can be treated efficiently. In particular, the pharmaceutical composition comprising a siRNA molecule of the present invention is effectively used in the treatment of a cancer, particularly pancreatic cancer. In addition, the siRNA or the antibody of the present invention can inhibit the expression or function of MUC5AC, thereby preventing or treating the symptoms of asthma effectively.
US08389706B2	Vaccines for human papilloma virus and methods for using the same Improved anti-HPV immunogens and nucleic acid molecules that encode them are disclosed. Immunogens disclosed include those having consensus HPV 18 E6 and E7. Pharmaceutical composition, recombinant vaccines comprising and live attenuated vaccines are disclosed as well methods of inducing an immune response in an individual against HPV are disclosed.
US08389696B2	Polymerizable diazonium salts, process for the preparation thereof and uses thereof Polymerizable diazonium salts having redox properties and absorption in the visible range, a process for preparing them and uses thereof are disclosed. The salts have the general formula: [XX+LnDdEm(N2+)p][(B−)p+x] in which: X is chosen from transition metals, preferably X is chosen from ruthenium (Ru), osmium (Os), iron (Fe), cobalt (Co) and iridium (Ir), x is an integer ranging from 1 to 5 inclusive, L is a ligand chosen from pyridine, bipyridine, terpyridine, phenanthroline and phenylpyridine groups, and mixtures thereof, n is an integer ranging from 1 to 5 inclusive, D is a saturated or unsaturated, C1-C5 alkyl spacer compound, d=0 or 1, E is an aromatic or polyaromatic spacer compound that can contain one or more heteroatoms, m is an integer ranging from 0 to 5 inclusive, p is an integer, and B is a counterion.
US08389695B2	Selenium containing modifying agents and conjugates The invention relates to a modifying agent comprising a water soluble polymer, wherein the water soluble polymer comprises at least one reactive selenium group, said reactive selenium group being capable of reacting with a thiol group thereby forming an —Se—S— bond. Furthermore, the invention relates to a method for producing said modifying agents and their use in the modification of pharmaceutically active agents, e.g. G-CSF. Additionally, the invention concerns conjugates comprising a water-soluble polymer and a pharmaceutically active agent, wherein the water-soluble polymer is linked via a S—Se-bond to agent and a method for their production and their use as medicaments. Finally, the invention concerns a pharmaceutical composition comprising the inventive conjugates.
US08389694B2	Biologically active antibodies recognizing a cell surface molecule selectively expressed on living mouse natural type one (I) interferon producing cells An isolated and characterized monoclonal antibody (“440c”) prepared by immunizing Wistar/CRL rats subcutaneously with purified rat bone marrow IPC, fusing popliteal lymph nodes of the rats with SP2/0 myeloma spleen cells and differentially selecting for hybridome supernatants that successfully stain bone marrow derived IPC and fractions thereof using CD11c+ spleen cells and, differentially selecting for hybridoma supernatants from the CD11c+ spleen cells that successfully stain only CD 11 c+/Ly6c+/CD 11 b−/B220+ splenocytes to provide the monoclonal antibody.
US08389692B2	Anti-platelet membrane glycoprotein VI monoclonal antibody The present invention provides an antibody which has the following features, its active fragment, or a derivative thereof: a) It specifically binds to human platelet membrane glycoprotein VI (GPVI); b) The function to activate a platelet and/or the function to induce a thrombocytopenia in vivo are low; and c) It at least partially depletes GPVI on the platelet membrane by contacting with a platelet.
US08389686B2	Noncovalent collagen crosslinking agent The present invention provides a collagen crosslinking agent superior in biocompatibility that is free from the damage by UV irradiation and also from the problems of toxicity caused by residual monomer or unreacted functional groups. Provided is a noncovalent collagen crosslinking agent (for fibrous protein collagen), comprising a spacer of a polyvalent alcohol having two or more OH groups at the terminals and arms of collagen peptides formed of repetitions of three amino acids, the arms being bound via the OH groups to the spacer.
US08389685B2	Vector encoding a plasmid replication protein and use thereof To provide a plasmid vector having high productivity which can be used for large scale production of an industrially valuable and useful protein, and a transformant using the plasmid vector. A plasmid vector having DNA which encodes a plasmid replication protein in which one or more amino acid residues that are selected from (a) position 48, (b) position 262, (c) position 149 and (d) position 198 in the amino acid sequence represented by SEQ ID NO: 2 are substituted with (a) Ala, Gly, Thr, Arg, Glu, Asn or Gln, (b) Gly, Ser, Thr, Cys or Val, (c) Asn, and (d) Glu, respectively.
US08389683B2	Bacillus thuringiensis gene with coleopteran activity The invention provides nucleic acids, and variants and fragments thereof, obtained from strains of Bacillus thuringiensis encoding polypeptides having pesticidal activity against insect pests, including Coleoptera. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.
US08389682B2	Inhibiting Staphylococcus epidermidis infections The invention relates to Staphylococcus epidermidis peptides, antibodies and nucleic acids that can inhibit Staphylococcus epidermidis infection of a mammalian subject and colonization of a medical device in the mammal.
US08389676B2	Biotinylation tag peptides Biotinylation peptides are provided which can be fused with other peptides or proteins of interest using recombinant DNA techniques to provide efficient methods for biotinylating the resulting fusion proteins in vivo or in vitro.
US08389671B2	Resin composition for optical member and optical member obtained from the same The present invention can provide a composition for optical members, which contains (a) a compound having one or more of any group selected from the group consisting of an acryloyl group, a methacryloyl group, an allyl group and a vinyl group and one or more β-epithiopropyl groups in a molecule. In a preferable embodiment of the present invention, the composition for optical members further contains at least one compound selected from (b) a compound having one or more β-epithiopropyl groups in a molecule while having no polymerizable unsaturated bond group, (c) an inorganic compound having a sulfur atom and/or a selenium atom, (d) a compound having one or more thiol groups in a molecule, (e) a compound having one or more amino groups in a molecule while having no heterocyclic ring, and (f) a compound having one or more of at least one group selected from the group consisting of a vinyl group, an acryloyl group, a methacryloyl group and an allyl group in a molecule.
US08389670B2	Dithienobenzo-thieno[3,2-B]thiophene-copolymer and its use as high performance solution processable semiconducting polymer Dithienobenzo-thieno[3,2-b]thiophene-copolymers of the formula (I) wherein: pi is a monocyclic or polycyclic moiety optionally substituted with 1-4 Ra groups, wherein Ra, at each occurrence, is independently hydrogen or a) a halogen, b) —(CN, c) —NO2, d) oxo, e) —OH, f) ═C(Rb)2; g) a C1-20 alkyl group, h) a C2-20 alkenyl group, i) a C2-20 alkynyl group, j) a C1-20 alkoxy group, k) a C1-20 alkylthio group, l) a C1-20 haloalkyl group, m) a —Y—C3-10 cycloalkyl group, n) a —Y—C6-14 aryl group, o) a —Y-3-12 membered cycloheteroalkyl group, or p) a —Y-5-14 membered heteroaryl group, wherein each of the C1-20 alkyl group, the C2-20 alkenyl group, the C2-20 alkynyl group, the C3-10 cycloalkyl group, the C6-14 aryl or haloaryl group, the 3-12 membered cycloheteroalkyl group, and the 5-14 membered heteroaryl group is optionally substituted with 1-4 Rb groups; Y, at each occurrence, is independently a divalent C1-6 alkyl group, a divalent C1-6 haloalkyl group, or a covalent bond; and R1, R2, R3, at each occurrence, are independently H, a halogen, CN, a C1-30 alkyl group, a C2-30 alkenyl group, a C1-30 haloalkyl group, a C2-30 alkynyl group, a C1-30 alkoxy group, a C(O)—C1-20 alkyl group, a C(O)—OC1-20 alkyl group, a Y—C3-10 cycloalkyl group, a —Y-3-12 membered cycloheteroalkyl group, each optionally substituted with 1-5 substituents selected from a halogen, —CN, a C1-6 alkyl group, a C1-6 alkoxy group, and a C1-6 haloalkyl group, -L-Ar1, -L-Ar1—Ar1, -L-Ar1—R4, or -L-Ar1—Ar1—R4 and Y, at each occurrence, is independently a divalent C1-6 alkyl group, a divalent C1-6 haloalkyl group, or a covalent bond; n=0, 1, 2; and o=1-1000.
US08389669B2	Fused thiophenes, methods for making fused thiophenes, and uses thereof Described herein are compositions including heterocyclic organic compounds such as fused thiophene compounds, methods for making them, and uses thereof.
US08389667B2	Partially crystalline polyethyleneterephthalate The invention relates to a partially crystalline polyethylene terephthalate having a degree of polymerization which is greater than 80, particularly greater than 100, produced from a diol component and a dicarboxylic acid component, wherein according to the invention the DSC melting point, when measured with a heating rate of 10° C./Min during the first passage and second passage, is less than the melting temperature (Tm) of a comparable standard polyethylene terephthalate which is dependent upon the comonomer content. The inventive method for the production of a polyethylene terephthalate comprises a step for the production of a polycondensate prepolymer melt; a step for the formation of granules and the solidification of the polycondensate prepolymer melt; a step for increasing the degree of crystallization of the prepolymer granulates and a step for increasing the molecular weight of the granulates by means of solid phase polycondensation, wherein according to the invention a treatment temperature of 220° C. in step d) is not exceeded.
US08389663B2	Photo-patternable dielectric materials curable to porous dielectric materials, formulations, precursors and methods of use thereof Silsesquioxane polymers that cure to porous silsesquioxane polymers, silsesquioxane polymers that cure to porous silsesquioxane polymers in negative tone photo-patternable dielectric formulations, methods of forming structures using negative tone photo-patternable dielectric formulations containing silsesquioxane polymers that cure to porous silsesquioxane polymers, structures containing porous silsesquioxane polymers and monomers and method of preparing monomers for silsesquioxane polymers that cure to porous silsesquioxane polymers.
US08389661B2	Complexes between an amphiphilic polymer and an osteogenic protein belonging to the family of BMPs The invention relates to an amphiphilic-BMP polymer complex which is physically and chemically stable and soluble in water, characterized in that: the amphiphilic polymers comprise a hydrophilic polysaccharide skeleton functionalized with hydrophobic substituents and hydrophilic groups the BMP is selected from the group of therapeutically active BMPs (Bone morphogenetic Proteins), the polymer/BMP mass ratio is lower than or equal to 700. The invention also relates to the process for preparing the amphiphilic-BMP polymer complex in an aqueous medium and in the absence of organic solvents likely to denature the protein.The invention also relates to therapeutic compositions of an amphiphilic-BMP polymer complex according to the invention.
US08389659B2	Emulsion polymers, aqueous dispersions and method for producing the same The present invention relates to an emulsion polymer comprising at least one (meth)acrylate segment which comprises 1% to 30% by weight of units derived from (meth)acrylates which in the alkyl radical have at least one double bond and 8 to 40 carbon atoms, 0.1% to 10% by weight of units derived from monomers containing acid groups, and 50% to 98.9% by weight of units derived from (meth)acrylates having 1 to 6 carbon atoms in the alkyl radical, based in each case on the weight of the (meth)acrylate segment, the emulsion polymer having a particle radius of at least 50 nm.
US08389657B2	Poly(meth)acrylamides and poly(meth)acrylates containing flourinated amide A composition comprising a copolymer having repeating units in any sequence of Formula I wherein Rf is a straight or branched perfluoroalkyl group which is optionally interrupted by at least one oxygen atom, X3 is oxygen or X1, each X1 is independently an organic divalent linking group, G is F or CF3, A is an amide, X2 is an organic linking group, Y is O, N or S, Z is H, a straight or branched alkyl group or halide, B is H or wherein Rf, X1, X3, G, and A are as defined above, and each W is independently various copolymer units.
US08389655B2	Catalyst composition comprising shuttling agent for higher olefin multi-block copolymer formation A process for preparing polymers, especially multi-block copolymer containing therein two or more segments or blocks differing in chemical or physical properties, by contacting propylene, 4-methyl-1-pentene, or other C4-8 α-olefins and one or more copolymerizable comonomers, especially ethylene in the presence of a composition comprising the admixture or reaction product resulting from combining: (A) a first metal complex olefin polymerization catalyst, (B) a second metal complex olefin polymerization catalyst capable of preparing polymers differing in chemical or physical properties from the polymer prepared by catalyst (A) under equivalent polymerization conditions, and (C) a chain shuttling agent.
US08389650B2	Curable polyorganosiloxane composition A curable polyorganosiloxane composition for use in an LED or optical lens, including: (A) an alkenyl group-containing polyorganosiloxane which contains a (A1) branched polyorganosiloxane including an SiO4/2 unit and an R3SiO1/2 unit, and optionally an R2SiO unit and/or an RSiO3/2 unit, wherein at least three R per molecule are vinyl groups, and optionally (A2) a linear polyorganosiloxane having R bonded to a silicon atom, wherein at least two R per molecule are vinyl groups, wherein 100 mol % or more of the R present in components (A1) and (A2), excluding alkenyl groups, are methyl groups; (B) a polyalkylhydrogensiloxane including an SiO4/2 unit and an R3(CH3)2SiO1/2 unit, the polyalkylhydrogensiloxane having the formula [R3(CH3)2SiO1/2]8[SiO4/2]4 or [R3(CH3)2SiO1/2]10[SiO4/2]5, wherein each R3 represents a hydrogen atom, and (C) a platinum-vinylsiloxane complex. The composition having desirable light transmission properties, and is unlikely to suffer yellowing due to exposure to heat.
US08389649B2	Siloxane-based resin composition The present invention is a siloxane-based resin composition including a siloxane-based resin and an imidosilane compound having a specific structure. Moreover, the present invention is a siloxane-based resin composition including a siloxane-based resin which is a reactive product to be obtained by hydrolyzing an alkoxysilane compound and an imidosilane compound having a specific structure and then making the resulting hydrolysate undergo a condensation reaction. According to the present invention, it is possible to form a cured film excellent in adhesion.
US08389645B2	Initiating system for solid polyester granule manufacture The invention relates to solid polyester granules of the type used as matting agents in paints. In particular, the invention relates to a new redox initiating system for use in a suspension polymerization process that is used to manufacture the solid polyester granules, to a process for the preparation of the solid polyester granules, and to paint compositions containing the solid polyester granules.
US08389639B2	Modified hyper-branched polymer and proton exchange membrane applied with the same, and method for manufacturing the proton exchange membrane A proton exchange membrane comprising modified hyper-branched polymer is disclosed. The proton exchange membrane includes 85-90 wt % of sulfonated tetrafluorethylene copolymer and 15-10 wt % of modified hyper-branched polymer. The modified hyper-branched polymer comprises the bismaleimide (BMI)-based hyper-branched polymer, and parts of the chain ends of the hyper-branched polymer are sulfonated by the sulfonic compound. Also, the modified hyper-branched polymer and sulfonated tetrafluorethylene copolymer are interpenetrated to form an interpenetrating polymer. Furthermore, the modification step could be performed before or after forming the interpenetrating polymer. For example, the sulfonation is proceeded after forming the interpenetrating polymer. Alternatively, the sulfonation of the hyper-branched polymer could be proceeded before the formation of the interpenetrating polymer.
US08389638B2	Multifunctional additive grafted rubber and process for the preparation thereof The present invention relates to a novel multi functional additive grafted rubber. More particularly the present invention relates to novel grades of rubber and in particular to chemically grafted with cardanol (meta-penta decenyl phenol) and/or its derivatives. Importantly the rubber grades of the invention involve chemically anchored/grafted selective meta alkenyl phenol and/or its derivatives in the backbone of natural or synthetic rubber. Importantly, such rubber variant of the invention have high plasticity, lower Mooney and melt viscosities, better cure properties as compared to conventional virgin natural rubber or natural rubber plasticized with aromatic process oils.
US08389637B2	Use of copolymers with a composition gradient as stabilizers in emulsion free-radical polymerization The present invention describes the use of copolymers with a composition gradient as sole stabilizer in emulsion free-radical polymerization. The copolymers of the invention are prepared via controlled free-radical polymerization and comprise at least one hydrophilic monomer such as acrylic acid and at least one hydrophobic monomer such as styrene.
US08389635B2	Polypropylene composition for buried structures The present disclosure describes a polypropylene resin composition useful for the preparation of buried structures such as corrugated, non-pressure pipe.
US08389634B2	Polymer compositions comprising a low-viscosity, homogeneously branched ethylene α-olefin extender A thermoplastic composition is described that comprises (i) from 1 to 99 percent by weight of the total composition of at least one thermoplastic copolymer, for example, styrene block copolymers, and (ii) from 1 to 99 percent by weight of the total composition of at least one homogeneously branched ethylene/α-olefin interpolymer, for example ethylene/1-octene, having a density of less than or equal to 0.899 g/cc and a Brookfield viscosity of greater than 500 cP (350° F.).
US08389630B2	Curable composition Provided is a curable composition excellent in curability and mechanical properties as well as a cured product thereof. Specially provided is a curable composition containing a vinyl-based polymer (I) having one or more crosslinkable functional groups at a terminus on average and a nucleophilic agent (II) and a cured product obtained by curing the curable composition. Preferably, the curable composition of the invention further contains an epoxy resin (III).
US08389629B2	Adhesive, adhesive sheet, multi-layered adhesive sheet, and production method for electronic part A multi-layered adhesive sheet 100, includes: a substrate film 106, an adhesive layer 103 formed by coating an adhesive having a specific composition onto this substrate film 106, and a die attachment film 105 laminated on the adhesive layer 103. The multi-layered adhesive sheet 100 employing an adhesive having this specific composition has superior retention of die chip 108 during the dicing of silicon wafer 101, allows the die attachment film 105 and adhesive layer 103 to be easily peeled apart during a pick-up operation of the die chip 108, and prevents poor adhesion during the bonding of die chip 108 to lead frame 111.
US08389626B2	Polycarbonate nanocomposites Polycarbonate nanocomposites comprising a polycarbonate matrix having non-oxidized metal nanoparticles dispersed therein are disclosed. The polycarbonate nanocomposite is produced by a process comprising forming a reaction mixture comprising a dihydroxy compound, an activated carbonate, a metal precursor, and a solvent; and in-situ polymerizing the reaction mixture to form a nanocomposite comprising a polycarbonate matrix and metal nanoparticles dispersed therein. The metal precursor comprises a metal selected from a specified group. The nanocomposites have improved mechanical, optical, electrical and/or magnetic properties. Also disclosed are articles formed from such polycarbonate nanocomposites.
US08389623B2	Nitrile rubbers An improved polymerization and work-up process makes it possible to produce specific nitrile rubbers which have a particular ion index and a particular magnesium content which is responsible for an excellent vulcanization rate and leads to vulcanizates having an advantageous property profile.
US08389622B2	Non-aqueous pigment ink A non-aqueous pigment ink comprising a pigment, a pigment dispersant and a non-aqueous solvent, wherein the pigment dispersant is an acrylic polymer comprising, as constituent monomers, (M1) an alkyl (meth)acrylate having an alkyl group of 12 or more carbon atoms, (M2) a (meth)acrylic acid derivative having an amino group, and (M3) (meth)acrylic acid and/or a (meth)acrylic acid derivative having a carboxyl group, in which a combination of all the constituent monomers comprises from 8 to 15 mol % of the monomer (M2) and from 0.6 to 8 mol % of the monomer (M3), and the molar ratio (M2)/(M3) between the monomer (M2) and the monomer (M3) is within a range from 1.3 to 15.
US08389620B2	Dip forming latex composition containing crosslinking agent and dip formed article obtained therefrom A dip-forming composition, comprising: a carboxyl group-containing diene-based rubber latex; and one or more compounds selected from the following (a) to (e): (a) an organometallic crosslinking agent containing two or more hydroxyl groups each bonded to a metal atom; (b) a cationic property-deactivated modified polyamine-based resin, a cationic property-deactivated polyamide-epichlorohydrin resin, a cationic property-deactivated polyamine-epichlorohydrin resin, a cationic property-deactivated amine group- or quaternary ammonium base-containing polyvinyl alcohol, a cationic property-deactivated amine group- or quaternary ammonium base-containing polyacrylamide, a cationic property-deactivated amine group- or quaternary ammonium base-containing carbohydrate, or a polyacrylamide, polyvinyl alcohol, or carbohydrate into which a crosslinkable functional group is introduced; (c) an anionic or nonionic polyvinyl alcohol, anionic or nonionic polyacrylamide, or anionic or nonionic carbohydrate to which a water resistant additive or water-resistant polymer is added; (d) a water resistant polyvinyl alcohol; and (e) a cationizing agent.
US08389618B2	Cold shrinkable article including an epichlorohydrin composition A composition includes an elastomeric composition. The elastomeric composition can include an epichlorohydrin composition, and the elastomeric composition can be substantially free of a fluoroelastomer composition. The composition can further include a filler material which includes a reinforcement-grade carbon black. The composition can further include a peroxide curative.
US08389617B2	Silicas The invention provides structurally modified, pyrogenically prepared silicas obtained by reaction of pyrogenic silicas with cyclic polysiloxanes of the type —[O—Si(R2)]n—, where R is a C1 to C6 alkyl group and n is 3 to 9, and subsequent structural modification of the silanized silicas obtained. The invention further provides an adhesive comprising the structurally modified, pyrogenically prepared silicas.
US08389616B2	Modifiers for nitrile containing elastomers This invention relates to a polymer composition comprising: 70 wt % to 99.5 wt % of a nitrile-group containing elastomer, wherein the elastomer has: a Mooney Viscosity of 15 to 115 MU; and a nitrile monomer content of 0.5 wt % to 50 wt %; and 0.5 wt % to 30 wt % of a non-functionalized plasticizer (NFP), wherein the NFP has: a kinematic viscosity at 100° C. of 4 to 1000 cSt, a flash point of ≧200° C., a viscosity index of ≧120, and a specific gravity of ≦0.865; and wherein the composition has: a 25% compression set at 70 hours and −30° C. that is at least 110% of the 25% compression set of same composition without the NFP tested at the same conditions, and a retained tensile strength, in MPa, after 168 hours at 175° C., that is at least about 88% of the retained tensile strength of the same composition that has not been aged.
US08389615B2	Elastomeric compositions comprising vinylaromatic block copolymer, polypropylene, plastomer, and low molecular weight polyolefin A composition comprising: (i) at least one low molecular weight polyolefin; (ii) at least one block copolymer obtainable by selectively hydrogenating a block copolymer having terminal polymeric blocks of a vinyl aromatic monomer and a mid-block prepared originally with an olefin and subsequently hydrogenated; (iii) at least one polypropylene; and (iv) at least one plastomer, wherein the plastomer is an ethylene based polymer having a density of 0.86 g/cc to about 0.910 g/cc or a propylene based polymer having a heat of fusion (Hf) of 70 J/g or less.
US08389613B2	Aqueous emulsions comprising polyisocyanate/acetal solvent compositions and coatings/adhesives produced therefrom Water-emulsifiable polyisocyanate compositions admixed with at least one solvent of formula (1) (R1O)2C(R2)—X—R3 are formulated into aqueous emulsions which advantageously further comprise a compound, bearing a mobile hydrogen function, or a compound containing precursor functions capable of liberating hydroxyl functions, and are useful for producing coatings on a variety of substrates, e.g., made of cement, wood or leather in particular, and also for producing adhesives.
US08389609B2	Multiple-acid-derived metal soaps incorporated in rubber compositions and method for incorporating such soaps in rubber compositions A composition includes a polymer matrix, a multiple-acid-derived metal soap, wherein the metal has an oxidation state of +3 or +4. An associated method for making a rubber composition includes the steps of: combining a solvent and a multiple carboxylic, phosphonic, phosphoric, sulfuric, or sulfonic acid, or mixtures thereof, and mixing to form solution A; adding a source of metal ions to solution A and mixing to form a product A, the metal being selected from the metals having an oxidation state of +3 or +4, whereby product A includes a multiple-acid-derived metal soap; and combining the multiple-acid-derived metal soap with a diene rubber. A method of making a tire component includes the steps of: combining a solvent and a multiple carboxylic, phosphonic, phosphoric, sulfuric, or sulfonic acid, or mixtures thereof, and mixing to form solution A; adding a source of metal ions to solution A and mixing to form a product A, the metal being selected from the metals having an oxidation state of +3 or +4, whereby product A includes a multiple-acid-derived metal soap; combining the multiple-acid-derived metal soap with a diene rubber; and molding and vulcanizing the rubber composition into a tire component.
US08389605B2	Self-repairing concrete having carbamide resin polymer micro-capsules and method for fabricating same A self-repairing concrete includes carbamide resin polymer micro-capsules, in which the carbamide resin polymer micro-capsules are mixed for a fixed function of micro-cracks. The quality mixture ratio is: concrete/micro capsules/water=100:1-15:15-50. The manufacturing method is weighing a full amount of water in a container, adding carbamide resin polymer micro-capsules, stirring, until fully dispersed microcapsules; pouring the water into the mixing container, adding the corresponding quality of cement; stirring; adding sand and gravel filling materials, conducting worksite watering, ⅓ volume for each time, vibrating, and air exhausting; until the slurry filling mold.
US08389604B2	Method for providing toughened poly(trimethylene terephthalate) molding resins Disclosed is a method including (A) melt blending first components including (a-1) a poly(trimethylene terephthalate) homopolymer or copolymer resin; and (a-2) one or more ionomer polymers or a combination of one or more ionomer polymers and acid polymers; to provide a first melt blend; and (B) melt blending said first melt blend with one or more Group B polymeric toughener(s) selected from the group consisting of an ethylene copolymers of the formula E/X/Y wherein: E is the radical formed from ethylene; X is selected from the group consisting of radicals formed from CH2═CH(R1)—C(O)—OR2 Y is one or more radicals formed from selected monomers with the proviso that Y must include at least one radical formed from monomers selected from the group consisting of maleic anhydride, (meth)acrylic acid, maleic acid, maleic acid monoesters, itaconic acid, fumaric acid, fumaric acid monoesters, salts of said preceding acids, and glycidyl acrylate, glycidyl methacrylate, and glycidyl vinyl ether.
US08389602B2	Ink composition for ink-jet recording, ink set and image forming method An ink composition for ink-jet recording, including: coloring particles containing a pigment that is coated with a water-insoluble polymer dispersant, and self-dispersing polymer particles containing a first polymer which includes a constituent unit derived from a hydrophilic monomer and a constituent unit derived from a hydrophobic monomer, and which has a glass transition temperature from 150° C. to 250° C. and an I/O value of from 0.20 to 0.55; an ink set including the ink composition; and an image forming method using the ink set are provided.
US08389601B2	Inkjet ink composition The invention is to provide a metal ink composition for ink-jet and more particularly, a metal ink composition which causes no formation of cracks on a PCB substrate, allows a low curing temperature, and provides improved adhesive strength even after coating.
US08389599B2	Dental composition comprising biphenyl di(meth)acrylate monomer comprising urethane moieties Dental compositions and biphenyl di(meth)acrylate monomers are described. The dental compositions comprise at least one biphenyl di(meth)acrylate monomer comprising two aromatic rings connected with a C—C bond wherein the rings each comprise a substituent comprising a urethane moiety and a (meth)acrylate end group.
US08389596B2	Low-tack, UV-cured pressure sensitive adhesive suitable for reclosable packages UV-cured pressure sensitive adhesive including one or more UV-curable acrylic oligomers, one or more tack control components, and, optionally, an elastomeric material is described herein. The adhesive includes an adhesive component ratio of the various adhesive components effective to provide desired first peel adhesions and subsequent peel adhesions.
US08389595B2	Production of superabsorbent polymers on a continuous belt reactor The invention relates to the production of superabsorbent polymers comprising polymerizing a monomer solution on a continuous belt reactor, wherein the consistency of the formed polymer gel at the end of the continuous belt reactor is controlled by adjusting the intensity of energy-rich radiation.
US08389589B2	Nanoporous media with lamellar structures A nanoporous material exhibiting a lamellar structure is disclosed. The material comprises three or more substantially parallel sheets of an organosilicate material, separated by highly porous spacer regions. The distance between the centers of the sheets lies between 1 nm and 50 nm. The highly porous spacer regions may be substantially free of condensed material. For the manufacture of such materials, a process is disclosed in which matrix non-amphiphilic polymeric material and templating polymeric material are dispersed in a solvent, where the templating polymeric material includes a polymeric amphiphilic material. The solvent with the polymeric materials is distributed onto a substrate. Organization is induced in the templating polymeric material. The solvent is removed, leaving the polymeric materials in place. The matrix polymeric material is cured, forming a lamellar structure.
US08389582B2	Composition for solubilizing tissue comprising 3-(decyl dimethyl ammonio) propane sulfonate and tetraethylene glycol dodecyl ether Tissue solubilizing compositions are provided. The compositions comprise 3-(decyl dimethyl ammonio) propane sulfonate and polyethylene glycol dodecyl ether, such as tetraethylene glycol dodecyl ether. The compositions may be useful to solubilize tissue, including skin, mucosal membrane, and other tissue. The compositions may be further useful to preserve and recover analytes contained within the solubilized skin, mucosal membrane, and other tissue.
US08389580B2	Arylcyclopropylamines and methods of use Described herein are arylcyclopropylamine compounds that may inhibit enzymes comprising an amine oxidase domain, such as LSD1, MAO A and/or MAO B.
US08389570B2	Hydroxamates as therapeutic agents The present invention is directed to certain hydroxamate derivatives that are useful in the treatment of hepatitis C. These compounds are also inhibitors of histone deacetylase and are therefore useful in the treatment of diseases associated with histone deacetylase activity. Pharmaceutical compositions and processes for preparing these compounds are also disclosed.
US08389563B2	C-substituted diindolylmethane compositions and methods for the treatment of multiple cancers The present embodiment of the invention is generally directed to compositions comprising suspensions of poorly water soluble compounds recrystallized in nanoparticulate sizes ranging from 0.1 to 5 μm. In addition, the embodiment of the invention is directed to methods for preparation and administration of these compositions to a patient for prevention and treatment of disease states. In particular, the embodiment of the invention is directed to compositions comprising suspensions of poorly water-soluble compounds, such as antimitotics and antibiotics, in nanoparticulates and methods of prevention and treatment of chronic disease states, such as cancer, by intraperitoneal and intravenous administration of such compositions.
US08389560B2	HCV protease inhibitors This invention relates to macrocyclic compounds of formula (I) shown in the specification. These compounds can be used to treat hepatitis C virus infection.
US08389556B2	Thiazolidinedione analogues The present invention relates to methods of using thiazolidinedione analogues of formula I: for treating Alzheimer's disease The terms R1, R2 and R3 are herein defined.
US08389554B2	Imidazothiadiazole derivatives Novel imidazo[2,1-b][1,3,4]thiadiazole derivatives of formula (I) wherein R1 and R2 have the meaning according to claim 1, are inhibitors of TGF-beta receptor I kinase, and can be employed, inter alia, for the treatment of tumors.
US08389551B2	Optical enantiomers of phenyramidol and process for chiral synthesis The present invention discloses optically pure (R) and (S) Phenyramidol enantiomers and their pharmaceutically acceptable salts, a process for synthesizing such enantiomers by means of a styrene oxide based synthesis, and also a clinical evaluation of (R) and (S) enantiomers of Phenyramidol, their salts and compositions thereof for enhanced/newer therapeutic benefits.
US08389530B2	Substituted quinazoline compounds The invention is directed to certain novel compounds, methods for producing them and methods for treating or ameliorating a kinase-mediated disorder. More particularly, this invention is directed to substituted quinazoline compounds useful as selective kinase inhibitors, methods for producing such compounds and methods for treating or ameliorating a kinase-mediated disorder, In particular, the methods relate to treating or ameliorating a kinase-mediated disorder including cardiovascular diseases, diabetes, diabetes-associated disorders, inflammatory diseases, immunological disorders, cancer and diseases of the eye such as retinopathies or macular degeneration or other vitreoretinal diseases, and the like.
US08389527B2	Substituted imidazopyridazines useful as kinase inhibitors The invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I imidazopyridazines inhibit protein kinase activity thereby making them useful as anticancer agents.
US08389526B2	3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives The invention relates to compounds of formula (I) and salts thereof wherein the substituents are as defined in the specification, the application of a compound of formula (I) in a process for the treatment of the human or animal body, in particular with regard to C-Met tyrosine kinase mediated disease; the use of a compound of formula (I) for manufacturing a medicament for the treatment of such diseases; pharmaceutical compositions comprising a compound of the formula (I), optionally in the presence of a combination partner; processes for the preparation of a compound of formula (I).
US08389524B2	Tricyclic nitrogen containing compounds as antibacterial agents Tricyclic nitrogen containing compounds and their use as antibacterials. Z1 and Z2 are independently selected from CH and N.
US08389523B2	Substituted quinoxaline and an agrochemical composition thereof The present invention is to provide an oxopyrazine derivative having an excellent herbicidal activity and besides exhibiting high safety for useful crops and the like, or a salt thereof, and a herbicide containing the same.The present invention relates to an oxopyrazine derivative represented by formula [I]: wherein X1 represents an oxygen atom or a sulfur atom; X2 represents CH or N(O)m; m represents an integer of 0 or 1; R1 represents a hydrogen atom, a C1-C12 alkyl group and the like; R2 represents a halogen atom, a cyano group and the like; R3 is a hydroxyl group, a halogen atom and the like; A1 represents C(R4R5); A2 represents C(R6R7) or C═O; A3 represents C(R8R9); R4 to R9 represent a hydrogen atom or an alkyl group, or a salt thereof, and a herbicide containing these compounds.
US08389522B2	Modulators of aldehyde dehydrogenase and methods of use thereof The present disclosure provides compounds that function as modulators of aldehyde dehydrogenase (ALDH) enzymatic activity, as well as compositions and formulations comprising the compounds. The present disclosure provides therapeutic methods involving administering a subject compound, or a subject pharmaceutical composition.
US08389518B2	Pyrazolo pyridine derivatives as NADPH oxidase inhibitors The present invention is related to pyrazolo pyridine derivatives of Formula (I), pharmaceutical composition thereof and to their use for the treatment and/or prophylaxis of disorders or conditions related to Nicotinamide adenine dinucleotide phosphate oxidase (NADPH Oxidase).
US08389515B2	2,4-pyrimidinediamine compounds and prodrugs and their uses The present disclosure provides biologically active 2,4-pyrimidinediamine compounds of formulae (I)-(III): and salts thereof, compositions comprising these compounds, and methods of using these compounds in a variety of applications.
US08389508B2	Heterocyclic compounds The present invention relates to novel compounds having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of various disorders.
US08389507B2	2-azetidinemethaneamines and 2-pyrrolidinemethaneamines as TAAR-ligands The present invention relates to compounds of formula I wherein R1, R2, R3, Ar, n and o are as defined herein and to their pharmaceutically acceptable active salts. Compounds of formula I have a good affinity to the trace amine associated receptors (TAARs), especially for TAAR1 and are useful for the treatment of depression, anxiety disorders, bipolar disorder, attention deficit hyperactivity disorder (ADHD), stress-related disorders, psychotic disorders such as schizophrenia, neurological diseases such as Parkinson's disease, neurodegenerative disorders such as Alzheimer's disease, epilepsy, migraine, hypertension, substance abuse and metabolic disorders such as eating disorders, diabetes, diabetic complications, obesity, dyslipidemia, disorders of energy consumption and assimilation, disorders and malfunction of body temperature homeostasis, disorders of sleep and circadian rhythm, and cardiovascular disorders.
US08389506B2	Compounds for therapy and diagnosis The present invention relates to a transition metal complex represented by Formula (I) or salts thereof, or to a ligand represented by Formula (H) or salts thereof, wherein X represents a transition metal, preferably Pt, and methods for their use and preparation. In particular, the invention relates to compounds which may possess useful therapeutic activity in treating amyloid diseases, and in particular, Alzheimer's disease. The invention also relates to the use of these compounds in methods of therapy, and diagnosis, and the manufacture of medicaments as well as compositions containing these compounds.
US08389505B2	Adamantane derivatives of AZA-crown ethers and their use in treatment of tumor The invention relates to adamantane diaza-crown ether derivatives and the use of mono and diaza-crown ether adamantine derivatives in treatment, especially in tumor treatment. Adamantane aza-crown ethers were obtained by reaction of the corresponding adamantane derived tosylates or adamantane acid chlorides with mono- and diaza-18-crown-6. The prepared compounds showed moderate (monoaza-18-crown-6) to strong (diaza-18-crown-6) antiproliferative and cytotoxic activity on several tumor cell lines, revealing their potential for inhibiting the growth of other tumor cells.
US08389501B2	Anticancer compound Azadirachta indica cell suspension culture is used to metabolize dianabol to yield potent anticarcinogenic 17β-hydroxy-17α-methyl-5α-androst-1-en-3-one, which can also be synthesized.
US08389498B2	Spinning solution and method for manufacturing biomaterial fibers Disclosed herein are spinning solutions and methods for manufacturing a biomaterial fiber. The spinning solution includes a biologically absorbable material having a haemostatic function, a polysaccharide selected from the group consisting of hyaluronic acid (HA) and gelatin, and a solvent, wherein the polysaccharide and the haemostatic material exist in a weight ratio between about 0.1 to about 3. The method includes steps of wet spinning the spinning solution into the biomaterial fiber.
US08389495B2	Olioodeoxynucleotide and its use to induce an immune response A substantially pure or isolated oligodeoxynucleotide of at least 10 nucleotides is disclosed, wherein the oligodeoxynucleotide comprised a sequence represented by either formula: 5′N1N2N3T-CpG-WN4N5N63′ wherein the CpG motif is unmethylated, W is A or T, and N1, N2, N3, N4, N5, and N6 are nucleotides, or the formula: 5′RY-CpG-RY3′ wherein the central CpG motif is unmethylated, R is A or G, and Y is C or T, as well as an oligodeoxynucleotide delivery complex and a pharmacological composition comprising the present inventive oligodeoxynucleotide, and a method of inducing an immune response by administering the present inventive oligodeoxynucleotide to a host. In some embodiments, the oligodeoxynucleotide includes the nucleic acid sequences set forth as SEQ ID NO: 137.
US08389494B2	p185neu-encoding DNA and therapeutical uses thereof Methods for inhibiting the formation and growth of a p185neu positive tumor in a subject, and for treating a subject having a p185neu positive tumor, utilizing a DNA vector coding for a chimeric rat/human Her-2/neu/ErbB-2 protein are provided.
US08389493B2	Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes AS-oligonucleotides are delivered in microsphere form in order to induce dendritic cell tolerance, particularly in the non-obese-diabetic (NOD) mouse model. The microspheres incorporate antisense (AS) oligonucleotides. A process includes using an antisense approach to reverse an autoimmune diabetes condition in NOD mice in vivo. The oligonucleotides are targeted to bind to primary transcripts CD40, CD80, CD86 and their combinations.
US08389491B2	Bispecific antisense oligonucleotides that inhibit IGFBP-2 and IGFBP-5 and methods of using same Bispecific antisense oligonucleotides which consist essentially of a sequence of bases that is complementary to portions of both the gene encoding human IGFBP-2 and the gene encoding human IGFBP-5 are useful in as antisense therapeutics in the treatment of endocrine-regulated cancers.
US08389489B2	Modulators of coagulation factors The invention provides improved nucleic acid ligands that inhibit coagulation and improved modulators of the nucleic acid ligands to provide ideal modulators of coagulation. These improved nucleic acid ligands and modulators are particularly useful for inhibiting coagulation in a host undergoing a therapeutic regime such as surgery or coronary artery bypass.
US08389486B2	Methods for treating hematopoietic malignancies Described herein are compositions and methods for the prevention and treatment of hematopoietic malignancies. The compositions are miRNAs and associated nucleic acids.
US08389485B2	Encapsulated nanoparticles for nucleic acid delivery Methods and compositions for delivering agents (e.g., gene silencing agents) and molecules to cells using yeast cell wall particles are presented herein. Embodiments of the invention are particularly useful for the delivery of nucleic acids (e.g., siRNAs) to cells.
US08389482B2	Short peptides useful for treatment of ischemia/reperfusion injury and other tissue damage conditions associated with nitric oxide and its reactive species This invention discloses isolated short peptides comprising the amino acid sequence Cys-Glu-Phe-His (CEFH; SEQ ID NOS: 1 and 15) and analogs thereof as well as compositions comprising CEFH peptides and analogs thereof. The CEFH peptides disclosed herein are effective in mediating the denitration of 3-nitrotyrosines (3-NT) in cellular proteins thereby preventing tissue damage associated with excess nitric oxide (NO) and its reactive species. The CEFH peptides disclosed herein are useful in the treatment of ischemia/reperfusion (I/R) injury of various tissues (e.g., I/R injury of heart muscle associated with heart attack or cardiac surgery, I/R injury of brain tissue associated with stroke, I/R injury of liver tissue, skeletal muscles, etc.), septic shock, anaphylactic shock, neurodegenerative diseases (e.g., Alzheimer's and Parkinson's diseases), neuronal injury, atherosclerosis, diabetes, multiple sclerosis, autoimmune uveitis, pulmonary fibrosis, oobliterative bronchiolitis, bronchopulmonary dysplasia (BPD), amyotrophic lateral sclerosis (ALS), sepsis, inflammatory bowel disease, arthritis, allograft rejection, autoimmune myocarditis, myocardial inflammation, pulmonary granulomatous inflammation, influenza- or HSV-induced pneumonia, chronic cerebral vasospasm, allergic encephalomyelitis, central nervous system (CNS) inflammation, Heliobacterium pylori gastritis, necrotizing entrerocolitis, celliac disease, peritonitis, early prosthesis failure, inclusion body myositis, preeclamptic pregnancies, skin lesions with anaphylactoid purpura, nephrosclerosis, ileitis, leishmaniasis, cancer, and related disorders.
US08389477B2	Amylin and amylin agonists for treating psychiatric diseases and disorders Methods and compositions for treating psychiatric diseases and disorders are disclosed. The methods provided generally involve the administration of an amylin or an amylin agonist to a subject in order to treat psychiatric diseases and disorders, and conditions associated with psychiatric diseases and disorders.
US08389476B2	Parstatin peptides and uses thereof The invention provides parstatin peptides, particularly a mammalian parstatin peptide including amino acids 1-26 of full length mammalian parstatin, preferably a human parstatin. The invention provides parstatin peptides in appropriate pharmaceutical carriers and formulated for administration. The invention provides for the use of the peptide for example as a medicament or for the preparation of a medicament. The invention provides methods of use for parstatin peptides including for inhibition of angiogenesis, for example for inhibition of ocular angiogenesis, for methods of cardioprotection, and for methods of prevention and treatment of myocardial ischemia-reperfusion injury.
US08389475B2	Relaxin analogs Human relaxin analogs, polypeptide compositions related thereto, as well as nucleotide compositions encoding the same, are provided.
US08389467B2	In situ self-setting mineral-polymer hybrid materials, composition and use thereof The present invention relates to self-setting compositions consisting in admixed liquid and solid components enable the formation of hardened bio-materials having a broad range of properties and performances. The present invention proposes a) a thermo-sensitive self-gelling liquid component, being water-based, comprising at least a polycationic and a phosphate source, wherein the liquid component is a thermo-gelling solution at a pH ranging from 6.5 to 7.4; b) a powder component consisting in at least two calcium phosphate sources. The preferred calcium phosphate source includes apatites, tricalcium phosphates, tetracalcium phosphates and dicalcium phosphates. Both solid and liquid components are admixed to form a flowable slurry that sets in situ into a hardened calcium phosphate based bio-material.
US08389460B2	Clothes washing method and surfactant-free detergent composition used for the same The present invention washes clothes using a phosphorous-free detergent composition for clothes, which contains an organic alkaline chelating agent as an essential ingredient, and an anti-soil redeposition agent, but no surfactant.
US08389459B2	Septic system cleaning compositions A composition including the fermentation supernatant from a fermentation of yeast is intended to be conveniently introduced through the wastewater plumbing system of a private home or other facility into a septic system servicing the home or other facility to substantially accelerate the ability of the bacteria resident in the septic system to substantially digest biologically available organic compounds present in the septic system, and methods of accomplishing the same.
US08389457B2	Quaternary functionalized alkyl polyglucosides for enhanced food soil removal A cleaning composition including a primarily C12 quaternary functionalized alkyl polyglucoside, a water conditioning agent, an acid source, a solvent, and water. In one embodiment, the cleaning composition is substantially free of alkyl phenol ethoxylates. The cleaning composition is capable of removing soils including up to 20% proteins. The cleaning compositions include a biorenewable, environmentally friendly alternative to nonyl phenol ethoxylates and exhibit superior cleaning of food soils.
US08389456B2	Low interfacial tension surfactants for petroleum applications The invention relates to a class of novel surfactants that have utility in the recovery and/or extraction of oil.
US08389451B2	Lubricant air release rates The air release rate of lubricating compositions is significantly enhanced when the composition is formulated with one or more vinyl aromatic-olefin block copolymers that forms a micelle-like structure in the oil. Compositions having the specified copolymers retain less than about 2.5% air after 1 min. at 50° C. when tested by ASTM D 3427.
US08389447B2	Organophilic clay additives and oil well drilling fluids with less temperature dependent rheological properties An additive composition including a synergistic combination of a hectorite organoclay composition and an attapulgite organoclay composition. The hectorite organoclay composition includes (i) a first organic cation provided by an alkoxylated quaternary ammonium salt; and ii) a second organic cation wherein such second organic cation is not provided by an alkoxylated quaternary ammonium salt. The attapulgite organoclay composition includes (iii) a third organic cation provided by an alkoxylated quaternary ammonium salt; and (iv) a fourth organic cation wherein such third organic cation is not provided by an alkoxylated quaternary ammonium salt.
US08389446B2	Swellable polymers with hydrophobic groups The invention is directed to crosslinked water-soluble swellable polymers, methods for making same and their various uses. More particularly, the invention relates to a composition comprising expandable polymeric particles being made with 0.1-5% hydrophobic monomers and labile crosslinkers and stable crosslinkers, said particles mixed with a fluid. A particularly important use is as an injection fluid in petroleum production, where the expandable polymeric particles are injected into a well and when the heat and/or pH of the target zones in the formation cause degradation of the labile crosslinker and when the particle expands, the hydrophobic groups associate to form a hydrophobically associative polymer, thus diverting water to lower permeability regions and improving oil recovery.
US08389438B2	Non-cylindrical catalytic-converter carrier element and tool, and method for manufacturing it A method for the production of a converter-carrier body having a metallic honeycomb body made of a plurality of metal layers, especially smooth layers and corrugated layers, the layers having layer ends, such that an outer shape of the honeycomb body is formed by the layer ends. At least one stack is produced having several alternately disposed metal layers that are structured such that channels are formed for a fluid to flow through. The at least one stack is transformed into a honeycomb body having a cylindrical form. The honeycomb body is deformed from the cylindrical form so that an outer shape that deviates from the cylindrical form is produced. Additionally, the invention relates to a corresponding converter-carrier body and a tool for the production thereof.
US08389436B2	Composite oxide A composite oxide is provided which has large oxygen absorption and desorption over a wide temperature range, in particular in a higher temperature range of not lower than 700° C. and/or in a lower temperature range of not higher than 400° C. The composite oxide contains oxygen, R composed of at least one of Ce and Pr, and Zr at a particular ratio, and optionally a particular ratio of M composed of at least one element selected from alkaline earth metals and the like.
US08389435B2	Metal oxide catalyst carrier particle and exhaust gas purification catalyst A metal oxide catalyst carrier particle has a center portion and an outer skin portion each containing a first metal oxide and a second metal oxide. The center portion and the outer skin portion are different in composition. The mole fraction of the metal of the first metal oxide is higher in the center portion than in the outer skin portion and the mole fraction of the metal of the second metal oxide is higher in the outer skin portion than in the center portion. The second metal oxide is selected from the group consisting of rare earth oxides, except for ceria, and alkali earth metal oxides. In addition, platinum is supported on the metal oxide catalyst carrier particle, thus forming an exhaust gas purification catalyst.
US08389433B2	Hydroprocessing bulk catalyst and methods of making thereof A hydroprocessing bulk catalyst is provided. A process to prepare hydroprocessing bulk catalysts is also provided. The hydroprocessing catalyst has the formula (Rp)i(Mt)a(Lu)b(Sv)d(Cw)e(Hx)f(Oy)g(Nz)h, wherein M is at least at least a “d” block element metal; L is also at least a “d” block element metal, but different from M; t, u, v, w, x, y, z representing the total charge for each of the components (M, L, S, C, H, O and N, respectively); R is optional and in one embodiment, R is a lanthanoid element metal; 0<=i<=1; pi+ta+ub+vd+we+xf+yg+zh=0; 0
US08389429B2	Composite ceramic body A composite ceramic body with increased strength is disclosed. The composite ceramic body, composed of a matrix of alumina particles with a mean particle diameter ranging from 0.7 to 1.8 μm and nano-zirconia particles with a particle diameter of 0.15 μm or less, wherein the alumina particles and the nano-zirconia particles fall in a respective weight percentage ratio ranging from 80:20 to 95:5 with a relative density of 93% or more and wherein in a cross section, a total sum of surface areas of pores, having cross-sectional areas equal to or greater than surface areas of circles having the same diameters as a mean particle diameter of the alumina particles, falls in a value of 2.2% or less based on a whole of the cross-sectional areas.
US08389426B2	Bicomponent fiber The present invention relates to a new bicomponent fiber, a nonwoven fabric comprising said new bicomponent fiber and sanitary articles made therefrom. The bicomponent fiber contains a polyethylene-based resin forming at least part of the surface of the fiber longitudinally continuously and is characterized by a Co-monomer Distribution Constant greater than about 45, a recrystallization temperature between 85° C. and 110° C., a tan delta value at 0.1 rad/sec from about 15 to 50, and a complex viscosity at 0.1 rad/second of 1400 Pa.sec or less. The nonwoven fabric comprising the new bicomponent fiber according to the instant invention are not only excellent in softness, but also high in strength, and can be produced in commercial volumes at lower costs due to higher thoughputs and requiring less energy.
US08389423B2	Semiconductor device manufacturing method One embodiment of the present invention provides a semiconductor device manufacturing method, including: performing a laser spike annealing, by irradiating light, whose wavelength is 10 μm to 11 μm, onto a semiconductor substrate including: an active area; a circuit pattern; and a dummy pattern formed at a position, whose distance from an end of the active area is equal to or more than 10 μm and equal to or less than 11 μm, at a pitch equal to or more than 10 nm and equal to or less than 510 nm, while setting an angle formed between an arrangement direction of the dummy pattern and a projection direction of the light to be equal to or more than 0° and equal to or less than 30°.
US08389420B2	Method and apparatus for forming silicon oxide film A method of forming a silicon oxide film on silicon exposed on a surface of a workpiece includes mounting the workpiece on a mounting table in a processing chamber; generating plasma of a process gas containing oxygen by supplying the process gas into the processing chamber; applying a bias to the workpiece by supplying high-frequency power to the mounting table; and forming the silicon oxide film by applying the plasma to the biased workpiece and oxidizing the silicon. A ratio of oxygen in the process gas is set to be in the range of 0.1% to 10%. A pressure in the processing chamber is set to be in the range of 1.3 Pa to 266.6 Pa upon forming the silicon oxide film. An output of the high-frequency power is set to be in the range of 0.14 W/cm2 to 2.13 W/cm2 per unit area of the workpiece.
US08389417B2	Semiconductor device and manufacturing method thereof An object is to provide a semiconductor device with a novel structure. A semiconductor device includes a first transistor, which includes a channel formation region provided in a substrate including a semiconductor material, impurity regions, a first gate insulating layer, a first gate electrode, and a first source electrode and a first drain electrode, and a second transistor, which includes an oxide semiconductor layer over the substrate including the semiconductor material, a second source electrode and a second drain electrode, a second gate insulating layer, and a second gate electrode. The second source electrode and the second drain electrode include an oxide region formed by oxidizing a side surface thereof, and at least one of the first gate electrode, the first source electrode, and the first drain electrode is electrically connected to at least one of the second gate electrode, the second source electrode, and the second drain electrode.
US08389416B2	Process for etching silicon with selectivity to silicon-germanium A method for performing a selective etching process is described. The method includes preparing a substrate having a silicon layer (Si) and a silicon-germanium (SiGex) layer, and selectively etching the silicon layer relative to the silicon-germanium layer using a dry plasma etching process.
US08389414B2	Method of manufacturing a wiring board A wiring board has an insulating layer, a plurality of wiring layers formed in such a way as to be insulated from each other by the insulating layer, and a plurality of vias formed in the insulating layer to connect the wiring layers. Of the wiring layers, a surface wiring layer formed in one surface of the insulating layer include a first metal film exposed from the one surface and a second metal film embedded in the insulating layer and stacked on the first metal film. Edges of the first metal film project from edges of the second metal film in the direction in which the second metal film spreads. By designing the shape of the wiring layers embedded in the insulating layer in this manner, it is possible to obtain a highly reliable wiring board that can be effectively prevented from side etching in the manufacturing process and can adapt to miniaturization and highly dense packaging of wires.
US08389412B2	Finishing method for a silicon on insulator substrate The invention relates to a finishing method for a silicon-on-insulator (SOI) substrate that includes an oxide layer buried between an active silicon layer and a support layer of silicon. The method includes applying the following steps in succession: a first rapid thermal annealing (RTA) of the SOI substrate; a sacrificial oxidation of the active silicon layer of the substrate conducted to remove a first oxide thickness; a second RTA of the substrate; and a second sacrificial oxidation of the active silicon layer conducted to remove a second oxide thickness that is thinner than the first oxide thickness.
US08389411B2	Method of managing substrate The electrostatic chuck is made up of: a chuck main body having electrodes; a chuck plate of a dielectric material and having a rib portion with which a peripheral edge portion of the substrate is capable of coming into surface contact, and a plurality of supporting portions which are vertically disposed at a predetermined distance from one another in an inner space enclosed by the rib portion; and a gas introduction means for introducing a predetermined gas into the inner space. When the substrate is held by the electrostatic chuck which is arranged to attract the substrate by the chuck plate and to form a gas atmosphere by supplying a predetermined gas into the inner space, a current value is monitored by causing an AC current to flow in a capacitance of the chuck plate through an AC power supply, a gas flow amount is monitored by causing the gas to flow through the gas introduction means, and a substrate state is managed based on a variation in at least one of the current value and the gas flow amount to prevent damages to the substrate.
US08389407B2	Methods of patterning materials Some embodiments include methods of forming openings. For instance, a construction may have a material over a plurality of electrically conductive lines. A plurality of annular features may be formed over the material, with the annular features crossing the lines. A patterned mask may be formed over the annular features, with the patterned mask leaving segments of the annular features exposed through a window in the patterned mask. The exposed segments of the annular features may define a plurality of openings, and such openings may be transferred into the material to form openings extending to the electrically conductive lines.
US08389404B2	Semiconductor device and method for manufacturing the same A semiconductor device includes a first substrate and a second substrate being bonded to each other, a posterior interconnect layer interposed between the first and second substrates, a weld pad disposed in the posterior interconnect layer, and a first annular opening disposed in the first substrate. The device further includes a dielectric layer formed in the first opening, a via surrounded by the first annular opening, and an interconnect layer disposed in the via. The device also includes a conductive bump disposed on the interconnect layer and electrically connected to the weld pad through the interconnect layer.
US08389399B2	Method of fabricating a self-aligning damascene memory structure A method of forming a memory cell is provided, the method including forming a first pillar-shaped element comprising a first semiconductor material, forming a first mold comprising an opening self-aligned with the first pillar-shaped element, and depositing a second semiconductor material in the opening to form a second pillar-shaped element above the first pillar-shaped element. Other aspects are also provided.
US08389398B2	Method of forming vertically offset bond on trace interconnects on recessed and raised bond fingers A method of making a semiconductor device comprises providing a carrier, forming a first conductive layer extending above a surface of the carrier, providing a substrate, disposing the first conductive layer into a first surface of the substrate, removing the carrier, forming a second conductive layer extending above the first surface of the substrate to create a vertical offset between the first conductive layer and second conductive layer, and forming a plurality of first bumps over the first conductive layer and second conductive layer. The method further includes the steps of disposing a third conductive layer into a second surface of the substrate opposite the first surface of the substrate, forming a fourth conductive layer extending above the second surface of the substrate to create a vertical offset between the third conductive layer and fourth conductive layer, and forming a plurality of second bumps.
US08389397B2	Method for reducing UBM undercut in metal bump structures A method of forming a device includes providing a wafer including a substrate; and forming an under-bump metallurgy (UBM) layer including a barrier layer overlying the substrate and a seed layer overlying the barrier layer. A metal bump is formed directly over a first portion of the UBM layer, wherein a second portion of the UBM layer is not covered by the metal bump. The second portion of the UBM layer includes a seed layer portion and a barrier layer portion. A first etch is performed to remove the seed layer portion, followed by a first rinse step performed on the wafer. A second etch is performed to remove the barrier layer portion, followed by a second rinse step performed on the wafer. At least a first switch time from the first etch to the first rinse step and a second switch time from the second etch to the second rinse step is less than about 1 second.
US08389395B2	Method for manufacturing semiconductor optical device A method for manufacturing includes the steps of forming a BCB resin region on a semiconductor optical device; processing a surface of the BCB resin region with inductively coupled plasma produced with a high-frequency power supply for supplying ICP power and a high-frequency power supply for supplying bias power, thus forming a silicon oxide film on the surface of the BCB resin region and roughening the surface of the BCB resin region with projections and recesses; and forming an electrode pad on the surface of the BCB resin region in direct contact with the silicon oxide film. The surface roughness of the BCB resin region and the thickness of the silicon oxide film on the surface of the BCB resin region are controlled by adjusting the bias power and the ICP power.
US08389393B2	Nanoparticle synthesis A noble metal nanoparticle can be grown on a semiconductor substrate by contacting a predetermined region of the substrate with a solution including noble metal ions. The predetermined region of the semiconductor substrate can be exposed by applying a polymeric layer over the substrate selectively removing a portion of the polymeric layer. The nanoparticles can be prepared in a predetermined pattern. The nanoparticle can be formed with a barrier separating it from another nanoparticle on the substrate; for example, nanoparticle can be located in a pit etched in the substrate. The size and location of the nanoparticle can be stable at elevated temperatures.
US08389391B2	Triple-gate transistor with reverse shallow trench isolation Example embodiments provide triple-gate semiconductor devices isolated by reverse shallow trench isolation (STI) structures and methods for their manufacture. In an example process, stacked layers including a form layer over a dielectric layer can be formed over a semiconductor substrate. One or more trenches can be formed by etching through the stacked layers. The one or more trenches can be filled by an active area material to form one or more active areas, which can be isolated by remaining portions of the dielectric layer. Bodies of the active area material can be exposed by removing the form layer. One or more triple-gate devices can then be formed on the exposed active area material. The example triple-gate semiconductor devices can control the dimensions for the active areas and provide less isolation spacing between the active areas, which optimizes manufacturing efficiency and device integration quality.
US08389390B2	Method of impurity introduction and controlled surface removal A method of introducing an impurity into a wafer surface is provided. The method comprises the steps of: low energy implantation of impurity into a surface of the wafer to generate an implanted dopant layer; and simultaneously removing an implanted surface of the implanted dopant layer to generate a doping profile with controlled areal impurity dosage.
US08389388B2	Photonic device and method of making the same A photonic device (200) and method (100) of making the photonic device (200) employs preferential etching of grain boundaries of a polycrystalline semiconductor material layer (210). The method (100) includes growing (110) the polycrystalline layer (210) on a substrate (201). The polycrystalline layer includes a transition region (212) of variously oriented grains and a region (214) of columnar grain boundaries (215) adjacent to the transition region. The method further includes preferentially etching (120) the columnar grain boundaries to provide tapered structures (220) of the semiconductor material that are continuous (217) with respective aligned grains (213) of the transition region. The tapered structures are predominantly single crystal. The method further includes forming (140) a conformal semiconductor junction (240) on the tapered structures and providing (160) first and second electrodes. The first electrode (201, 262) is adjacent to the transition region and the second electrode (260) is adjacent to a surface layer of the conformal semiconductor junction.
US08389385B2	Semiconductor material manufacture Electronic apparatus, systems, and methods include a semiconductor layer bonded to a bulk region of a wafer or a substrate, in which the semiconductor layer can be bonded to the bulk region using electromagnetic radiation. Additional apparatus, systems, and methods are disclosed.
US08389384B2	Laser beam machining method and semiconductor chip An object to be processed 1 comprising a substrate 4 and a plurality of functional devices 15 formed on a front face 3 of the substrate 4 is irradiated with laser light L while locating a converging point P within the substrate 4, so as to form at least one row of a divided modified region 72, at least one row of a quality modified region 71 positioned between the divided modified region 72 and the front face 3 of the substrate 4, and at least one row of an HC modified region 73 positioned between the divided modified region 72 and a rear face 21 of the substrate 4 for one line to cut 5. Here, in a direction along the line to cut, a forming density of the divided modified region 72 is made lower than that of the quality modified region 71 and that of the HC modified region 73.
US08389383B1	Patterned semiconductor bases, and patterning methods Some embodiments include patterning methods. First and second masking features may be formed over first and second regions of a semiconductor base, respectively. A protective mask may be formed over the second masking features. First and second spacers may be formed along sidewall edges of the first masking features and along lateral edges of the protective mask, respectively. The protective mask and the first masking features may be removed without removing the second masking features, without removing the first spacers, and without removing the second spacers. The first spacers may be third masking features that are at a tighter pitch than the first masking features. Patterns of the second masking features and the third masking features may be transferred into the semiconductor base. Some embodiments include patterned semiconductor bases.
US08389382B2	Method for manufacturing bonded wafer A method for manufacturing a bonded wafer including the steps of: implanting at least one gas ion of a hydrogen ion and a rare gas ion into a bond wafer from a surface thereof to form an ion-implanted layer; bonding the ion-implanted surface of the bond wafer to a surface of a base wafer directly or through an oxide film; thereafter delaminating the bond wafer at the ion-implanted layer to prepare the bonded wafer having a silicon thin film formed on the base wafer; and performing a flattening heat treatment on the bonded wafer under an atmosphere containing hydrogen or hydrogen chloride, wherein a dopant gas is added into the atmosphere of the flattening heat treatment to perform the heat treatment, the dopant gas having the same conductivity type as a dopant contained in the silicon thin film.
US08389374B1	Method for producing a microfabricated in-plane radio frequency (RF) capacitor The present invention is a method for producing a capacitor. The method includes applying a dielectric substance (ex.—silicon nitride) to a first gold seed layer, the first gold seed layer being formed on a wafer. A second gold seed layer is formed upon the dielectric substance and first gold seed layer. Gold is electroplated into a photoresist to form a first set of 3-D capacitor elements on the second gold seed layer. A first copper layer is electroplated onto the second gold seed layer. Gold is electroplated into a photoresist to form a second set of 3-D capacitor elements, the second set of 3-D elements being formed at least partially within the first copper layer and being connected to the first set of 3-D elements. A second copper layer is electroplated onto the first copper layer. Then, both copper layers are removed to provide (ex.—form) the capacitor.
US08389371B2	Method of fabricating integrated circuit device, including removing at least a portion of a spacer A method for fabricating an integrated device is disclosed. A sacrificial gate stack is provided with a line width narrower than the target width of the final gate structure. After performing a tilt-angle implantation process, L-shape spacers are formed over the sidewalls of the sacrificial gate stack, and offset spacers are formed over the sidewalls of the L-shape spacers. An insulating layer is formed over the offset spacers and the substrate. Then, the sacrificial gate stack and the L-shape spacers are removed to form a trench in the insulating layer. A metal gate is then filled in the trench to form the final gate structure.
US08389370B2	Radiation-tolerant integrated circuit device and method for fabricating An enhanced shallow trench isolation method for fabricating radiation tolerant integrated circuit devices is disclosed. A layer of pad oxide is first deposited on a semiconductor substrate. A layer of pad nitride is then deposited on the pad oxide layer. A trench is defined within the semiconductor substrate by selectively etching the pad nitride layer, the pad oxide layer, and the semiconductor substrate. Boron ions are then implanted into both the bottom and along the sidewalls of the trench. Subsequently, a trench plug is formed within the trench by depositing an insulating material into the trench and by removing an excess portion of the insulating material. A p-well is implanted to a depth just below the depth of the bottom of the trench. This helps to keep the threshold voltage of the IC device below the trench at a high level, and thereby keep post-radiation leakage low. Then, an electrically neutral species is implanted into the wafer.
US08389369B2	Electronic device including a doped region disposed under and having a higher dopant concentration than a channel region and a process of forming the same An electronic device can include a drain region of a transistor, a channel region of the transistor, and a doped region that is disposed under substantially all of the channel region, is not disposed under substantially all of a heavily doped portion of the drain region, and has a higher dopant concentration compared to the channel region. A process of forming an electronic device can include forming a drain region, a channel region, and a doped region, wherein the drain region has a conductivity type opposite that of the channel and doped region. After forming the drain, channel, and doped regions, the doped region is disposed under substantially all of the channel region, the doped region is not disposed under substantially all of a heavily doped portion of the drain region, and the drain region is laterally closer to the doped region than to the channel region.
US08389366B2	Resurf semiconductor device charge balancing Breakdown voltage BVdss is enhanced and ON-resistance reduced in RESURF devices (40, 60, 80, 80′, 80″), e.g., LDMOS transistors, by careful charge balancing, even when body (44, 44′, 84, 84′) and drift (50, 50′, 90, 90′) region charge balance is not ideal, by: (i) providing a plug or sinker (57) near the drain (52, 92) and of the same conductivity type extending through the drift region (50, 50′, 90, 90′) at least into the underlying body region (44, 44′ 84, 84′), and/or (ii) applying bias Viso to a surrounding lateral doped isolation wall (102) coupled to the device buried layer (42, 82), and/or (iii) providing a variable resistance bridge (104) between the isolation wall (102) and the drift region (50, 50′, 90, 90′). The bridge (104) may be a FET (110) whose source-drain (113, 114) couple the isolation wall (102) and drift region (50, 50′, 90, 90′) and whose gate (116) receives control voltage Vc, or a resistor (120) whose cross-section (X, Y, Z) affects its resistance and pinch-off, to set the percentage of drain voltage coupled to the buried layer (42, 82) via the isolation wall (102).
US08389365B2	Non-volatile memory and logic circuit process integration A method for forming an integrated circuit for a non-volatile memory cell transistor is disclosed that includes: forming a layer of discrete storage elements over a substrate in a first region of the substrate and in a second region of the substrate; forming a first layer of dielectric material over the layer of discrete storage elements in the first region and the second region; forming a first layer of barrier work function material over the first layer of dielectric material in the first region and the second region; and removing the first layer of barrier work function material from the second region, the first layer of dielectric material from the second region, and the layer of discrete storage elements from the second region. After the removing, a second layer of barrier work function material is formed over the substrate in the first region and the second region. The second layer of barrier work function material is removed from the first region. A first gate of a memory device is formed in the first region. The first gate includes a portion of the first layer of barrier work function material. The memory device includes a charge storage structure including a portion of the layer of discrete storage elements. A second gate of a transistor is formed in the second region, the second gate including a portion of the second layer of barrier work function material.
US08389361B2	Semiconductor device and method for fabricating thereof A silicon nitride film, which is a second hard mask, is dry etched to be removed completely. The silicon nitride film, which is formed on a sidewall of a silicon nitride film used as a first hard mask, has a relatively low etching rate. Therefore, if the silicon nitride film is continued etching until the corresponding portion thereof is removed, polysilicon is etched in a direction of depth in trench shape. Then, floating gates in adjacent cells are separated and a step portion of the polysilicon is formed. Consequently, a remaining portion of the silicon nitride film used as the first hard mask is removed, an ONO film is laminated on a whole surface of the poly silicon having the step portion on an edge that has been etched, and then, a polysilicon for a control gate is laminated on the ONO film.
US08389359B2	Method for forming low resistance and uniform metal gate The present disclosure provides a method that includes forming a high k dielectric layer on a semiconductor substrate; forming a polysilicon layer on the high k dielectric layer; patterning the high k dielectric layer and polysilicon layer to form first and second dummy gates in first and second field effect transistor (FET) regions, respectively; forming an inter-level dielectric (ILD); applying a first CMP process to the semiconductor substrate, exposing the first and second dummy gates; removing the polysilicon from the first dummy gate, resulting in a first gate trench; forming a first metal electrode in the first gate trench; applying a second CMP process; forming a mask covering the first FET region and exposing the second dummy gate; thereafter removing the polysilicon from the second dummy gate, resulting in a second gate trench; forming a second metal electrode in the second gate trench; and applying a third CMP process.
US08389358B2	Manufacturing method and structure of non-volatile memory A non-volatile memory structure includes a substrate; a poly gate structure formed on the substrate; a contact etching stop layer formed over the poly gate structure and including at least a silicon nitride layer and a first silicon oxide layer overlying the silicon nitride layer; and an inter-layer dielectric layer formed on the first silicon oxide layer. The first silicon oxide layer has a density higher than that of the inter-layer dielectric layer.
US08389353B2	Methods of forming an array of memory cells, methods of forming a plurality of field effect transistors, methods of forming source/drain regions and isolation trenches, and methods of forming a series of spaced trenches into a substrate A method of forming a series of spaced trenches into a substrate includes forming a plurality of spaced lines over a substrate. Anisotropically etched sidewall spacers are formed on opposing sides of the spaced lines. Individual of the lines have greater maximum width than minimum width of space between immediately adjacent of the spacers between immediately adjacent of the lines. The spaced lines are removed to form a series of alternating first and second mask openings between the spacers. The first mask openings are located where the spaced lines were located and are wider than the second mask openings. Alternating first and second trenches are simultaneously etched into the substrate through the alternating first and second mask openings, respectively, to form the first trenches to be wider and deeper within the substrate than are the second trenches. Other implementations and embodiments are disclosed.
US08389351B2	Method for fabricating semiconductor device A method for fabricating a semiconductor device is disclosed. A resist pattern is formed on a surface of a semiconductor layer in which a first layer and a second layer are sequentially formed on a substrate. A gate recess is formed by removing a part or the entire second layer in an opening area of the resist pattern. The resist pattern is removed. A dry etching residue attached to a bottom surface and lateral surfaces of the gate recess is removed after the resist pattern is removed. An insulating film is formed on the bottom surface, the lateral surfaces, and the semiconductor layer after the dry etching residue is removed. A gate electrode is formed via the insulating film on an area where the gate recess is formed. A source electrode and a drain electrode are formed on the semiconductor layer.
US08389350B2	Semiconductor device and method for manufacturing the same in which variations are reduced and characteristics are improved A method of manufacturing N-type MOSFET includes: implanting a p-type dopant into in a surface layer of a semiconductor substrate to form a channel region; forming a gate insulating film including High-k material and a gate electrode on said channel region; implanting a p-type dopant into both ends of said channel region in an inner portion of said semiconductor substrate to form halo regions; implanting a p-type dopant into both ends of said channel region in a surface layer of said semiconductor substrate to form extension regions. One of said step of forming said channel region and said step of forming halo regions includes: implanting C into one of said channel region and said halo regions. An inclusion amount of said High-k material is an amount that increase of a threshold voltage caused by said High-k material being included in said gate insulating film compensates for decrease of said threshold voltage caused by said C being implanted.
US08389348B2	Mechanism of forming SiC crystalline on Si substrates to allow integration of GaN and Si electronics The mechanisms of forming SiC crystalline regions on Si substrate described above enable formation and integration of GaN-based devices and Si-based devices on a same substrate. The SiC crystalline regions are formed by implanting carbon into regions of Si substrate and then annealing the substrate. An implant-stop layer is used to cover the Si device regions during formation of the SiC crystalline regions.
US08389345B2	Thin film transistor and manufacturing method of the same To achieve TFT having a high light-resistance characteristic with a suppressed light leak current at low cost by simplifying the manufacturing processes. The TFT basically includes: a light-shielding film formed on a glass substrate that serves as an insulating substrate; an insulating film formed on the light-shielding film; a semiconductor film formed on the insulating film; and a gate insulating film formed on the semiconductor film. Each layer of a laminate that is configured with three layers of the light-shielding film, the insulating film, and the semiconductor film is patterned simultaneously. Further, each layer of the laminate is configured with silicon or a material containing silicon.
US08389342B2	Method for manufacturing a semiconductor device A purpose of the invention is to provide a method for leveling a semiconductor layer without increasing the number and the complication of manufacturing processes as well as without deteriorating a crystal characteristic, and a method for leveling a surface of a semiconductor layer to stabilize an interface between the surface of the semiconductor layer and a gate insulating film, in order to achieve a TFT having a good characteristic. In an atmosphere of one kind or a plural kinds of gas selected from hydrogen or inert gas (nitrogen, argon, helium, neon, krypton and xenon), radiation with a laser beam in the first, second and third conditions is carried out in order, wherein the first condition laser beam is radiated for crystallizing a semiconductor film or improving a crystal characteristic; the second condition laser beam is radiated for eliminating an oxide film; and the third condition laser beam is radiated for leveling a surface of the crystallized semiconductor film.
US08389338B2	Embedded die package on package (POP) with pre-molded leadframe A multiple-chip package has top and bottom pre-molded leadframes formed prior to the flip-chip attachment of semiconductor die to the leadframes. After die attachment, underfill is used to encase all but one surface of the die, and the top and bottom leadframes are joined together by solder bump balls with the exposed surfaces of the semiconductor dice proximate to each other.
US08389334B2	Foil-based method for packaging intergrated circuits One aspect of the present invention involves a foil-based method for packaging integrated circuits. Initially, a metallic foil and a photoresist layer are attached with a carrier. The photoresist layer is exposed and patterned. Afterward, multiple integrated circuit dice are connected to the foil. The dice and portions of the foil are encapsulated in a molding material. The foil is then etched based on the patterned photoresist layer to define multiple device areas in the foil, where each device area supports at least one of the integrated circuit dice. Some aspects of the present invention relate to panel arrangements that are involved in the aforementioned method.
US08389333B2	Semiconductor device and method of forming EWLB package containing stacked semiconductor die electrically connected through conductive vias formed in encapsulant around die A semiconductor device has a first semiconductor die and first encapsulant deposited around the first semiconductor die. A first insulating layer is formed over the first semiconductor die and first encapsulant. A first conductive layer is formed over the first insulating layer and electrically connected to a contact pad of the first semiconductor die. A second semiconductor die is mounted to the first insulating layer and first conductive layer. A second encapsulant is deposited around the second semiconductor die. A second insulating layer is formed over the second semiconductor die and second encapsulant. A second conductive layer is formed over the second insulating layer and electrically connected to a contact pad of the second semiconductor die. A plurality of conductive vias is formed continuously through the first and second encapsulants outside a footprint of the first and second semiconductor die electrically connected to the first and second conductive layers.
US08389332B2	Integrated circuit packaging system with isolated pads and method of manufacture thereof A method of manufacture of an integrated circuit packaging system includes: providing a lead frame having a die attach paddle, an isolated pad, and a connector; attaching an integrated circuit die to the die attach paddle and the connector; forming an encapsulation over the integrated circuit die, the connector, the die attach paddle, and the isolated pad; and singulating the connector and the die attach paddle whereby the isolated pads are electrically isolated.
US08389331B2	Apparatus for restricting moisture ingress Apparatus and methods to protect circuitry from moisture ingress, e.g., using a metallic structure as part of a moisture ingress barrier.
US08389328B2	Method of manufacturing electronic device and electronic device Provided is a method of manufacturing an electronic device having a first electronic component having a first terminal and a second electronic component having a second terminal, wherein the first electric component is electrically connected to the second electronic component by connecting the first terminal to the second terminal with solder, the method including: providing a resin layer having a flux action between the first terminal and the second terminal to obtain a laminate including the first electronic component, the second electronic component, and the resin layer, wherein a solder is provided on the first terminal or the second terminal; soldering the first terminal and the second terminal; and curing the resin layer while pressing the laminate with a pressurized fluid.
US08389323B2	Method of manufacturing organic light emitting display apparatus, surface treatment device for organic light emitting display apparatus, and organic light emitting display apparatus Provided are a method of manufacturing an organic light emitting display apparatus, a surface treatment device for an organic light emitting display apparatus, and an organic light emitting display apparatus. To easily form organic emissive layers, the method includes: forming a first electrode on a substrate; forming on the first electrode a pixel defining layer having openings that expose predetermined portions of the first electrode; forming a charge carrying layer on the pixel defining layer and the first electrode exposed through the openings; hydrophobically treating portions of a surface of the charge carrying layer selectively, wherein the portions do not correspond to the openings, using a laser; forming organic emissive layers on the charge carrying layer; and forming a second electrode on the organic emissive layers so as to be electrically connected with the organic emissive layers.
US08389318B2	Method of producing a thin film photovoltaic system, and a thin film photovoltaic system A method of producing a thin film photovoltaic system (2) having a two-dimensional metal chalcogenide compound semiconductor layer (7) as an absorber of sunlight and a metal layer (8) applied to the metal chalcogenide compound semiconductor layer is provided, wherein the metal chalcogenide compound semiconductor layer (7) and the metal layer (8) form a Schottky contact at their contact face. The method is characterized in that the metal chalcogenide compound semiconductor layer (7) is produced by applying a dispersion containing nanoscale particles having a diameter of about 3 nm to about 30 nm to a transparent substrate material (12), wherein the layer thickness of the metal chalcogenide compound semiconductor layer (7) applied to the substrate material ranges from about 150 nm to about 2500 nm.
US08389308B2	Method for producing surface emitting semiconductor device A method for producing a surface emitting semiconductor device includes a step of forming a semiconductor stacked structure including an active layer, a first semiconductor layer containing aluminum on the active layer, and a DBR portion, on the first semiconductor layer, to include alternating stacked second semiconductor layers and third semiconductor layers having different aluminum contents; a step of forming a mesa portion by etching the DBR portion and the first semiconductor layer; an oxidation step of oxidizing the first semiconductor layer from a side face of the mesa portion toward the inside of the mesa portion to form an annular oxidized region inside the first semiconductor layer; a first etching step of selectively etching an oxidized region formed in the DBR portion; and a second etching step of removing a peripheral portion of the DBR portion.
US08389305B2	Techniques of forming ohmic contacts on GaN light emitting diodes A method of forming ohmic contacts on a light emitting diode that features a surface treatment of a substrate includes exposing a surface of a p-type gallium nitride layer to an acid-containing solution and a buffered oxide etch process. A quantum well is formed in a gallium nitride substrate and a layer of p-type gallium nitride is deposited over the quantum well. The surface of the p-type gallium nitride is exposed to an acid-containing solution and then a buffered oxide etch process is performed to provide an etched surface. A metal stack including a layer of silver disposed between layers of platinum is then deposited.
US08389304B2	Method for producing group III nitride semiconductor light-emitting device The present invention provides a method for producing a Group III nitride semiconductor light-emitting device, the device including a light-emitting layer which is formed so as to contour a stripe-pattern embossment and to have a uniform thickness. In the production method, firstly, a stripe-pattern embossment having a serrated cross section is formed on one surface of a substrate. Subsequently, on the surface of the substrate on the side of the stripe-pattern embossment having a serrated cross section, an n-type layer, a light-emitting layer, and a p-type layer are sequentially deposited through reduced-pressure MOCVD so as to contour the embossment. Thus, each of the layers is formed so as to contour the embossment, and to have a stripe pattern with a serrated cross section. In this MOCVD process, the direction of gas flow is parallel with the direction of the stripe of the embossment. Thus, the light-emitting layer has uniform thickness and composition in an in-plane direction.
US08389302B2	Method for measuring optoelectronic memory device A method for measuring an optoelectronic memory device, includes: grounding a source electrode of the optoelectronic memory device; applying a drain electrode voltage to a drain electrode of the optoelectronic memory device and measuring a first current at the drain electrode; using an optical source to illuminate the optoelectronic memory device and measure a first and a second current at the drain electrode; and comparing the sizes of the first current and the second current so as to judge the functional parameters of the optoelectronic memory device.
US08389293B2	Reducing leukocyte interference in competitive immunoassays The invention is directed to methods and devices for reducing interference from leukocytes in competitive analyte immunoassays. In one embodiment, the invention is to a method comprising the steps of (a) amending a biological sample such as a whole blood sample with sacrificial beads opsonized for leukocytes; and (b) performing a competitive immunoassay on the amended sample to determine the concentration of said analyte in said sample. Preferably, the sample is amended with IgG-coated sacrificial beads.
US08389291B2	System and method for the measurement of multiple fluorescence emissions in a flow cytometry system A system and method for the measurement of multiple fluorescence emissions in a flow cytometry system is disclosed where each excitation light source is modulated with a different frequency. A single detector is used to collect the fluorescent emissions excited by all light sources, and the emissions are segregated using Fourier Transform techniques. Systems and methods for the correction of inter-beam coincidence are also disclosed.
US08389288B2	Device for the carrying out of chemical or biological reactions The invention relates to a device for the carrying out of chemical or biological reactions with a reaction vessel receiving element for receiving a microtiter plate with several reaction vessels, wherein the reaction vessel receiving element has several recesses arranged in a regular pattern to receive the respective reaction vessels, a heating device for heating the reaction vessel receiving element, and a cooling device for cooling the reaction vessel receiving element.The invention is characterized by the fact that the reaction vessel receiving element is divided into several segments. The individual segments are thermally decoupled from one another, and each segment is assigned a heating device which may be actuated independently of the others.By means of the segmentation of the reaction vessel receiving element, it is possible for zones to be set and held at different temperatures. Since the reaction vessel receiving element is suitable for receiving standard microtiter plates, the device according to the invention may be integrated in existing process sequences.
US08389287B2	Sample collection method The present invention relates to methods for the collection of a sample from faecal material and, further, the detection of occult blood in or on the faecal material via the testing of the sample collected from the faecal material. The present invention also relates to collection methods comprising the use of a brush-like device having flexible or semi-flexible bristles wherein the brush-like device is contacted to the faecal material. The present invention also relates to detection of occult blood from the sample collected from the faecal material by means of a guaiac test or immunochromatographic test. The present invention additionally relates to the detection of one or more indicators of a pathological condition in or on the faecal material from which the sample is derived.
US08389284B2	Screening and treatment methods using IGS5 enzymes of the metalloprotease family Polypeptides which are related to the neprilysin enzyme family and have zinc metalloprotease activities and are referred to as IGS5, polynucleotides encoding such polypeptides, vectors containing such polynucleotides, host cells containing such vectors, processes for producing such polypeptides and/or polynucleotides, screening methods for identifying compounds which stimulate or inhibit IGS5 polypeptides and/or polynucleotides, and the use of such polypeptides and/or polynucleotides in therapy of various dysfunctions, disorders or diseases, particularly cardiovascular diseases, metabolic diseases such as diabetes mellitus type II, and neurodegenerative disorders, such as Parkinson's Disease.
US08389281B2	Materials and methods relating to the production and maintenance of cell lines The invention provides methods for maintaining cell lines from primary cells, i.e., non-transformed cells, using expression of the signal transducer of activation and transcription (STAT). The methods are particularly suitable for maintenance of B-cells.
US08389280B2	Method for perfusing an organ for isolating cells from the organ An organ perfusion apparatus and method monitor, sustain and/or restore viability of organs and preserve organs for storage and/or transport. Other apparatus include an organ transporter, an organ cassette and an organ diagnostic device. The method includes perfusing the organ at hypothermic and/or normothermic temperatures. The methods further include perfusing the organ at hypothermic and/or normothermic temperatures with a second perfusate containing a substance for reacting with the organ. Condition of the organ may be automatically monitored, and the perfusion process can be automatically controlled using a control program.
US08389279B2	α-aminocyclolactam ligands for G-protein coupled receptors, and methods of using same The invention relates to the generation of a library of compounds enriched in agonist and antagonists for members of the G-protein coupled class of receptors (GPCRs).The library contains compounds of general formula (I) wherein y is any integer from 1 to 8; z is any integer from 0 to 8 with the proviso that y and z cannot simultaneously be 1; X is —CO—(Y)k—(R1)n or SO2—(Y)k—(R1)n; k is 0 or 1 Y is a cycloalkyl or polycyloalkyl group (such as an adamantyl, adamantanemethyl, bicyclooctyl, cyclohexyl, cyclopropyl group); or Y is a cycloalkenyl or polycycloalkenyl group; each R1 is independently selected from hydrogen or an alkyl, haloalkyl, alkoxy, haloalkoxy, alkenyl, alkynyl, alkylamino, alkylaminoalkyl, alkylaminodialkyl, charged alkylaminotrialkyl or charged alkylcarboxylate radical of 1 to 20 carbon atoms; or each R1 is independently selected from fluoro, chloro, bromo, iodo, hydroxy, oxyalkyl, amino, aminoalkyl, aminodialkyl, charged aminotrialkyl, or carboxylate radical; and n is any integer from 1 to m, where m is the maximum number of substitutions permissible on the cyclo-group Y; or alternatively R1 may be selected from a peptido radical, for example having from 1 to 4 peptidic moieties linked together by peptide bonds (for example a peptido radical of 1 to 4 amino acid residues).
US08389276B2	Immortalized mouse fibroblast cell lines deficient in Bax and/or Bak The present invention relates to a composition comprising an immortalized cell line which is deficient in the expression of one or more gene(s) of the intrinsic apoptotic pathway, selected from the group consisting of Bax, Bak, and mixtures thereof. The present invention further relates to the product of a process for producing an immortalized mouse fibroblast cell line which is deficient in the expression of Bax, Bak, and mixtures thereof. Finally, the present invention relates to a method and a kit for identifying a compound or composition which induces or blocks the extrinsic apoptotic pathway.
US08389269B2	Production of secreted proteins by filamentous fungi The present invention relates to a method to improve the secretion of a protein of interest by a filamentous fungal cell comprising inducing a phenotype in the cell selected from the group consisting of a lowered ERAD, an elevated UPR that does not induce an elevated ERAD, wherein ERAD preferably is lowered. The invention further relates to the filamentous fungal cell comprising the phenotype described above. The invention also relates to polynucleotides and polypeptides whose expression can be modulated in the filamentous fungal cell to obtain the above-described phenotype.
US08389266B2	Lactic acid bacterium having effect of lowering blood uric acid level The present invention provides lactic acid bacteria which are suitable for use for dietary products and pharmaceuticals, and which can suppress the increase of blood uric acid level. Various types of lactic acid bacteria were cultured in the presence of a purine, the amount of the purine consumed and the amount of purine degradation products produced were measured, and several lactic acid bacteria showing remarkable purine-decomposing ability were selected. Lactic acid bacteria that were assessed to have high purine-decomposing ability according to the above-mentioned selection were orally administered to rats reared on purine-containing feed, the general status and serum uric acid level of the rats were measured, and the effect of lactic acid bacteria administration on serum uric acid levels was examined. As a result, lactic acid bacteria that significantly suppress the increase of serum uric acid levels, Lactobacillus gasseri OLL2922, were found.
US08389263B2	Spores for the stabilization and on-site application of bacterial whole-cell biosensing systems The presently-disclosed subject matter is directed to biosensors comprising spore-forming bacterial cells and/or spores generated therefrom, a recognition unit within each spore-forming cell for binding an analyte of interest, and a reporter molecule within each spore-forming cell for detecting binding of the analyte of interest, wherein the reporter molecule generates a detectable signal upon binding of the analyte by the recognition element. The presently-disclosed subject matter further provides methods of using the biosensors and systems and kits including the biosensors.
US08389262B2	Subtilase variants having altered immunogenicity The present invention relates to subtilase subtilases with an altered immunogenicity, particularly subtilases with a reduced allergenicity. Furthermore, the invention relates to expression of said subtilase variants and subtilases and to their use, such as in detergents and oral care products.
US08389253B2	Organic solvent pretreatment of biomass to enhance enzymatic saccharification Biomass is pretreated using an organic solvent solution under alkaline conditions in the presence of one or more alkylamine and optionally one or more additional nucleophile to fragment and extract lignin. Pretreated biomass is further hydrolyzed with a saccharification enzyme consortium. Fermentable sugars released by saccharification may be utilized for the production of target chemicals by fermentation.
US08389252B2	Yeast strain for production of four carbon alcohols Yeast cells with a reduced general control response to amino acid starvation were found to have increased tolerance to butanol in the growth medium. The reduced response was engineered by genetic modification of a gene involved in the response, a GCN gene, to eliminate activity of the encoded protein. Yeast strains with an engineered butanol biosynthetic pathway and a genetic modification in a gene involved in the general control response to amino acid starvation, which have increased butanol tolerance, are useful for production of butanol.
US08389247B2	Physiogenomic method for predicting diabetes and metabolic syndromes induced by psychotropic drugs The invention is generally directed to a physiogenomic method for predicting diabetes and metabolic syndromes induced by psychotropic drugs. In one embodiment, the invention relates to the use of genetic variants of marker genes to predict the likelihood that an individual will experience undesirable metabolic side effects as a result of the use of a drug including, but not limited to, psychotropic drugs. The invention also relates to methods predicting the likelihood of diabetes and metabolic syndromes induced by the use of drugs with undesirable metabolic side effects.
US08389242B2	Process for producing Apo2L A process is described for producing a polypeptide heterologous to E. coli wherein E. coli cells comprising nucleic acid encoding the polypeptide are cultured in a culture medium while feeding to the culture medium a transportable organophosphate, such that the nucleic acid is expressed. The polypeptide is then recovered from the cells.
US08389239B2	Enhanced expression and stability regions Expression-enhancing nucleotide sequences for expression in eukaryotic systems are provided that allow for enhanced and stable expression of recombinant proteins in eukaryotic cells. Enhanced expression and stability regions (EESYRs) are provided for expression of a gene of interest in a eukaryotic cell. Chromosomal loci, sequences, and vectors are provided for enhanced and stable expression of genes in eukaryotic cells.
US08389237B2	Antibodies against RAMP3 The present invention provides an isolated antibody capable of binding a receptor activity modifying protein (RAMP) of CRLR receptor which antibody is of IgG, IgA or IgM isotype.
US08389232B2	Fluorescence detection of poison oak oil The invention herein disclosed provides for compositions, methods for synthesizing said compositions, and methods for using said compositions, wherein the compositions and methods may be used to bind to and/or deactivate a poison oak oil, such as urushiol. The compositions and methods can be used to treat and/or reduce an inflammatory reaction and/or hypersensitivity to natural compounds found in poison oak, poison ivy, poison sumac, mango, lac tree, and cashew nut.
US08389231B2	Assays, method and compositions that exploit a mycobacterial iron acquistion pathway in cells Assays for the identification of antibacterial agents that inhibit mycobacterial growth by interfering with the iron acquisition pathway in host cells are disclosed. Also disclosed are methods of inhibiting mycobacterial growth by interfering with iron uptake or by delivering antibacterial agents to mycobacteria in host cells through the iron uptake pathway, as well as certain compounds that are useful in the assay methods, and also as antibacterial agents.
US08389228B2	Process for the measurement of the potency of glatiramer acetate The subject invention provides a process for measuring the relative potency of a test batch of glatiramer acetate. In addition, the subject invention provides a process for preparing a batch of glatiramer acetate as acceptable for pharmaceutical use.
US08389223B2	Probes for anionic cell surface detection Embodiments of the present invention are generally directed to compositions comprising a class of molecular probes for detecting the presence of anionic cell surfaces. Embodiments include compositions that are enriched for these compositions and preparations, particularly preparations suitable for use as laboratory/clinical reagents and diagnostic indicators, either alone or as part of a kit. An embodiment of the invention provides for a highly selective agent useful in the discernment and identification of dead or dying cells, such as apoptotic cells, in a relatively calcium-free environment. An embodiment of the invention provides a selective agent for the identification of bacteria in a mixed population of bacterial cells and nonbacterial cells.
US08389218B2	Analysis of single nucleotide polymorphisms using a nicking endonuclease A method of genome analysis is provided. In certain embodiments, the method comprises: a) contacting a double-stranded genomic DNA with a site-specific nicking endonuclease that recognizes a sequence comprising a single nucleotide polymorphism (SNP), in which the endonuclease nicks the genomic DNA at a nick site only if a first allele of the SNP is present; b) denaturing the genomic sample; c) contacting the denatured genomic sample with an array comprising a first probe and a second probe, in which nicking results in less binding of the denatured sample to the first probe relative to a sample that is not nicked; and d) comparing the amount of hybridization to the first probe to the amount of hybridization to said second probe, in which decreased binding of the denatured genomic samples to the first probe relative to the second probe indicates that the first allele of the SNP is present.
US08389214B2	Glucose transport mutants for production of biomaterial A method is disclosed for restoring a Glu+ phenotype to a PTS−/Glu− bacterial cell which was originally capable of utilizing a phosphotransferase transport system (PTS) for carbohydrate transport. Bacterial cells comprising the Glu+ phenotype have modified endogenous chromosomal regulatory regions which are operably linked to polynucleotides encoding galactose permeases and glucokinases.
US08389212B1	Method for the electronic analysis of a sample oligonucleotide sequence A self-addressable, self-assembling microelectronic device is designed and fabricated to actively carry out and control multi-step and multiplex molecular biological reactions in microscopic formats. These reactions include nucleic acid hybridization, antibody/antigen reaction, diagnostics, and biopolymer synthesis. The device can be fabricated using both microlithographic and micro-machining techniques. The device can electronically control the transport and attachment of specific binding entities to specific micro-locations. The specific binding entities include molecular biological molecules such as nucleic acids and polypeptides. The device can subsequently control the transport and reaction of analytes or reactants at the addressed specific micro-locations. The device is able to concentrate analytes and reactants, remove non-specifically bound molecules, provide stringency control for DNA hybridization reactions, and improve the detection of analytes. The device can be electronically replicated.
US08389210B2	MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors The present invention provides novel methods and compositions for the diagnosis, prognosis and treatment of pancreatic cancer. The invention also provides methods of identifying anti-pancreatic cancer agent.
US08389206B2	High normality solution for removing freeze material in lithographic applications A method for patterning a substrate is described. The method comprises forming a layer of radiation-sensitive material on the substrate, preparing a pattern in the layer of radiation-sensitive material, and applying a chemical freeze layer over the layer of radiation-sensitive material to form a frozen layer of radiation-sensitive material. Thereafter, the method comprises stripping the chemical freeze layer using a high normality strip solution to preserve the pattern in the frozen layer of radiation-sensitive material, wherein the high normality strip solution contains an active solute having a normality (N) greater than 0.26.
US08389202B2	Polymer, radiation-sensitive composition, monomer, and method of producing compound A polymer includes a repeating unit shown by a general formula (1). R1 represents a hydrogen atom, a methyl group, a fluorine atom, or a trifluoromethyl group. R2 represents a substituted or unsubstituted aryl group having 6 to 22 carbon atoms. Y represents a carbon atom. X represents —X1Z1X2— which is an atomic group which forms a cyclic structure including a heteroatom together with Y. Z1 represents —O—, —S—, —CO—, —COO—, —SO—, or —SO2—. Each of X1 and X2 individually represents a single bond, a methylene group, or an alkylene group having 2 to 25 carbon atoms. Each of X1 and X2 is unsubstituted or substituted with a substituent, and optionally a carbon atom included in X1 and a carbon atom included in X2 are bonded via a divalent group.
US08389196B2	Method of preparing toner Provided is a method of preparing a toner, the method including: preparing a solvent emulsion by stirring a medium including a polar medium, an organic solvent, and a surfactant; adding toner components including a resin and a pigment to the solvent emulsion; removing the organic solvent from the solvent emulsion including the toner components; and collecting a toner particle from the solvent emulsion from which the organic solvent is removed.
US08389191B2	Coated carriers The present disclosure provides carriers for use with toner compositions. In embodiments, a carrier may include a core, having a dry powder polymer coating. The polymer coating possesses a carbon to oxygen from about 3:1 to about 8:1. In embodiments, the coating may also include a colorant, such as carbon black. Processes for coating such carriers with the dry powder polymer coatings are also provided.
US08389189B2	Resin binders for toners The present invention relates to a resin binder for toners which includes core/shell particles each including a core portion containing a crystalline polyester obtained by polycondensing an alcohol component containing an aliphatic diol having 2-12 carbon atoms and a carboxylic acid component containing an aliphatic dicarboxylic acid compound having 8-12 carbon atoms in an amount of 70-100 mol %, and a non-crystalline resin (A) obtained by polycondensing an alcohol component and a carboxylic acid component containing at least one succinic acid compound selected from the group consisting of an alkyl (C9-C18) succinic acid and an alkenyl (C9-C18) succinic acid in an amount of 3-60 mol %; and a shell portion containing a non-crystalline resin (B) obtained by polycondensing a carboxylic acid component and an alcohol component containing an aliphatic dialcohol having 2-5 carbon atoms in an amount of 80 mol % or more.
US08389186B2	Toner set, developer set, image forming apparatus, and image forming method A toner set is composed of toners of a plurality of colors that are used in a tandem-type color image forming apparatus. Each of the toners of a plurality of colors includes toner base particles and an external additive. The external additive includes small-diameter silica particles and large-diameter silica particles larger than the small-diameter silica particles. When, of the toners of a plurality of colors, three color toners to be used consecutively for forming the toner image are defined as a first toner, second toner and third toner respectively in order of usage thereof, the average particle diameter of the large-diameter silica particles contained in the second toner is smaller than the average particle diameter of the large-diameter silica particles contained in the first toner and is larger than the average particle diameter of the large-diameter silica particles contained in the third toner.
US08389184B2	Reflective mask blank and method of manufacturing a reflective mask Disclosed is a reflective mask blank (10) which comprises a substrate (1), a multilayer reflective film (2) for reflecting exposure light, a buffer film (3), and an absorber film (4) for absorbing exposure light, said films being sequentially formed on the substrate. The absorber film (4) has a multilayer structure which is composed of an uppermost layer (4b) and a lower layer (4a). The uppermost layer is formed from a material containing oxide, oxynitride or carbide of Ta, and has a refractive index (n) of 0.95-0.97 and an extinction coefficient (k) of from −0.033 to −0.023. The lower layer is formed from a material containing Ta, and has a refractive index (n) of 0.94-0.97 and an extinction coefficient (k) of from −0.050 to −0.036. A reflective mask (20) can be obtained by forming a transfer pattern on the absorber film of the reflective mask blank.
US08389183B2	Chromeless phase-shifting photomask with undercut rim-shifting element A phase-shifting photomask with a self aligned undercut rim-shifting element and methods for its manufacture are provided. One embodiment of the invention provides a method of manufacturing a phase-shifting photomask having a self aligned rim-shifting element, the method comprising: applying a patterning film to a first portion of a transparent substrate; etching the substrate to a depth to remove a second portion of the substrate not beneath the patterning film; etching the first portion of the substrate to undercut an area beneath the patterning film; and removing the patterning film, wherein the etched substrate forms a self-aligned undercut rim-shifting element.
US08389180B2	Electrolytic/fuel cell bundles and systems including a current collector in communication with an electrode thereof Electrolytic/fuel cell bundles and systems including such bundles include an electrically conductive current collector in communication with an anode or a cathode of each of a plurality of cells. A cross-sectional area of the current collector may vary in a direction generally parallel to a general direction of current flow through the current collector. The current collector may include a porous monolithic structure. At least one cell of the plurality of cells may include a current collector that surrounds an outer electrode of the cell and has at least six substantially planar exterior surfaces. The planar surfaces may extend along a length of the cell, and may abut against a substantially planar surface of a current collector of an adjacent cell. Methods for generating electricity and for performing electrolysis include flowing current through a conductive current collector having a varying cross-sectional area.
US08389179B2	Fuel cell A fuel cell has cell units and a manifold for uniformly supplying an anode fluid to the cell units. The manifold has a fluid supply plate with a flow conduit for feeding an anode fluid, and a plate structure having a flow space and openings arranged in a preselected direction. The flow space receives an anode fluid fed from an opening part of the flow conduit, reduces a flow rate of the anode fluid, and disperses the anode fluid at the reduced flow rate along a plane direction orthogonal to the preselected direction. The block group is arranged between the openings and the opening part so that the flow space is disposed between the block group and the opening part. The block group comprises blocks spaced apart from one another to form paths for dispersing into the openings the anode fluid dispersed by the flow space at the reduced rate.
US08389177B2	Combined subgasket and membrane support A combined subgasket and membrane support for a fuel cell is provided. The combined subgasket and membrane support includes a substantially fluid impermeable feed region circumscribing a porous membrane support region. The membrane support region is integrally formed with the feed region. At least one of the membrane support region and the feed region is at least partially formed by a radiation-cured structure. A method for fabricating the subgasket and membrane support for the fuel cell is also provided.
US08389174B2	Super-hydrophilic nanoporous electrically conductive coatings for PEM fuel cells A flow field plate or bipolar plate for a fuel cell that includes a conductive coating having formed nanopores that make the coating hydrophilic. Any suitable process can be used to form the nanopores in the coating. One process includes co-depositing a conductive material and a relatively unstable element on the plate, and then subsequently dissolving the element to remove it from the coating and create the nanopores. Another process includes using low energy ion beams for ion beam lithography to make the nanopores.
US08389172B2	Fuel cell system A fuel cell system includes a fuel cell stack, a heat exchanger, a reformer, and a combustor. A combustion gas path for supplying the combustion gas produced in the combustor to the heat exchanger as the heat medium is provided. The combustion gas path is provided between a space of dual walls comprising a first inner plate and a second inner plate and a first case unit and a second case unit accommodating a load applying mechanism and the fuel cell stack.
US08389171B2	Preventing corrosion in a fuel cell The invention relates to a method for protecting a set of electrochemical cells incorporated into a fuel cell stack from corrosion during an operation for shutting down the fuel cell stack, which method comprises steps of: measuring the voltage across the terminals of each of the cells to be protected; when the voltage measured for a cell is above a protection threshold, discharging this cell into an electrical load; when the voltage measured for a cell is below said protection threshold, disconnecting this cell from the electrical load.
US08389168B2	Injector control for fuel cell system A fuel cell system that employs an injector/ejector for providing fresh hydrogen and anode recirculation gas to the anode side of a fuel cell stack. The injector/ejector is operated with a variable frequency so that the injector open time at low stack current densities is long enough to allow a pressure drop to be provided in the anode flow channels to push out water that may have accumulated therein. In one embodiment, the injector/ejector control provides a minimum pulse width per cycle and a maximum frequency so that as the stack current density decreases below a certain value the frequency decreases from the maximum frequency to maintain the pulse width constant at the minimum pulse width.
US08389165B2	Printed fuel cell with integrated gas channels A method of manufacturing a fuel cell includes applying a sacrificial material periodically to a surface of an anode substrate, wherein at least some areas of the anode substrate have no sacrificial material. A first gas diffusion layer is applied to the sacrificial material, and a first catalyst material is applied to the first gas diffusion layer. An electrolyte material is applied to the anode substrate and the first gas diffusion layer, with the catalyst material, wherein a first surface of the electrolyte material is in operative association with the anode substrate, and the first gas diffusion layer. A second catalyst material is applied to the second surface of the electrolyte material. A second gas diffusion layer is applied to the electrolyte material on a second surface of the electrolyte material, with the catalyst material, wherein a first surface of the second gas diffusion layer is in contact with the second surface of the electrolyte material with the catalyst material. A cathode is applied to the second gas diffusion layer with the second catalyst material, and the sacrificial material is then removed from the surface of the anode substrate to create integrated gas channels for the manufactured fuel cell.
US08389164B2	Nonaqueous electrolytic solution, positive electrode and nonaqueous electrolyte secondary battery A nonaqueous electrolytic solution includes an electrolyte salt dissolved in a nonaqueous solvent, wherein the nonaqueous electrolyte solution contains at least one compound selected from the group consisting of a chain compound having a hydroxyl group and a carbon-carbon double bond, a light metal alkoxide thereof and a derivative thereof obtained by substituting the hydroxyl group with a protective group.
US08389163B2	Lithium secondary battery containing organic peroxide in non-aqueous electrolyte, positive electrode, or negative electrode A lithium secondary battery includes a positive electrode including a positive electrode active material, a negative electrode including a negative electrode active material, and a non-aqueous electrolyte. The positive electrode active material comprises at least one lithium-containing composite oxide represented by the following general formula: LixM11−yM2yO2 where M1 and M2 are different elements, M1 is Ni or Co, M2 is at least one selected from Ni, Co, Mn, Mg, and Al, 1≦x≦1.05, and 0≦y≦0.7. The negative electrode active material comprises at least one selected from the group consisting of silicon, tin, a silicon-containing alloy, and a tin-containing alloy. The non-aqueous electrolyte includes an organic peroxide.
US08389162B2	Electrolyte for rechargeable lithium battery including additives, and rechargeable lithium battery including the same An electrolyte for a rechargeable lithium battery that includes a non-aqueous organic solvent, a lithium salt, and an electrolyte additive. The electrolyte additive includes 2 to 6 wt % of succinonitrile, 2 to 6 wt % of alkane sultone, and 1 to 3 wt % of vinylethylene carbonate based on the total weight of the electrolyte.
US08389159B2	Nickel metal hydride rechargeable battery and method for manufacturing negative electrode thereof A nickel metal hydride rechargeable battery has a closed-end tubular container containing a spiral-shaped electrode assembly formed by winding a negative a positive electrode with a separator interposed therebetween such that the outermost periphery of the assembly is the negative electrode which is formed by disposing on a conductive substrate a mixture layer containing a hydrogen-absorption alloy. The positive electrode employs nickel hydroxide as an active material. In the nickel metal hydride rechargeable battery, the surface roughness of the outermost peripheral portion of the mixture layer of the negative electrode which contacts an inner side wall of the closed-end tubular container is 3.5 μM or more in terms of ten-point average roughness and is larger than the surface roughness of the other portion of the mixture layer. The reduction of oxygen gas during rapid charging is thereby facilitated without lowering the design capacity of the battery.
US08389154B2	Battery cell design and method of its construction A compact, robust, multifunctional and highly manufacturable rechargeable battery cell is provided. The cell design dedicates minimal internal volume to inert components of the cell. This is accomplished, in part, by providing multiple functionalities to individual cell components.
US08389152B2	Pouch type polymer battery pack A polymer battery pack includes a core pack having a protective circuit module attached to a bare cell, a case having the core pack coupled thereto, the protective circuit module having a portion exposed to an exterior of the case, and a resin enclosing at least a portion of the protective circuit module that is exposed to the exterior of the case. A method of manufacturing a polymer battery pack includes forming a bare cell, forming a core pack having a protective circuit module, coupling the core pack to an interior of the case such that the protective circuit module is exposed to an exterior of the case, and molding the protective circuit module with a resin such that a terminal on the protective circuit module is exposed to an exterior of the resin.
US08389147B2	Hydrogels for aqueous lithium/air battery cells Li/air battery cells are configurable to achieve very high energy density. The cells include a protected a lithium metal or alloy anode and an aqueous catholyte in a cathode compartment. In addition to the aqueous catholyte, components of the cathode compartment include an air cathode (e.g., oxygen electrode) and a variety of other possible elements.
US08389146B2	Terminal unit and method of manufacturing the same The first aspect of the present invention is a terminal unit which contains an electrode part disposed in a case, for connecting with an electrode body and a terminal part having a rod shape with a first end and a second end, the first end for fixing to the electrode part, and the second end extending outside of the case. In one embodiment of the first aspect of the invention, the electrode part includes an insert hole into which the terminal part is inserted, the terminal part comprises an insert portion having an insert portion having a larger diameter than that of the hole and formed at the first end and a tip portion having a smaller diameter than that of the hole and formed at the nearer side of the first end than the insert portion. And, the clinch portion is press fitted into the insert hole, thereby fixing the terminal part to the electrode part. According to the present invention, the varying of electric conductivity in the terminal unit is prevented.
US08389138B2	Method of operating a non-balanced lithium-ion microbattery The lithium-ion microbattery comprises a positive electrode having a first Li+ ion storage capacity and a first thickness made from a first lithium insertion material, an electrolyte and a negative electrode having a second storage capacity and a second thickness made from a second insertion material. The thicknesses are such that the ratio of the first storage capacity over the second storage capacity is greater than or equal to 10 and lower than or equal to 1000. During the first charging of the micro-battery, the Li+ ions are inserted in the negative electrode and completely saturate the second insertion material. When initial charging is continued, they form a metallic lithium layer between the electrolyte and the lithium-saturated negative electrode by electroplating. During the subsequent charging and discharging cycles, only the metallic lithium layer participates in transfer of lithium ions.
US08389134B2	Body coated with hard material The invention relates to a body which is coated with hard material and has a plurality of layers applied by means of CVD, in which an Al2O3 layer is arranged as outer layer on a Ti1-xAlxN layer and/or Ti1-xAlxC layer and/or Ti1-xAlxCN layer.
US08389132B2	Organometallic complex, and light-emitting device and electronic appliance using the same In a general formula (1), each of R1 and R2 represents any one of hydrogen, an alkyl group, a halogen group, —CF3, an alkoxy group, and an aryl group. M represents an element that belongs to Group 9 or Group 10. Here, an alkyl group having 1 to 4 carbon atoms is preferable in the alkyl group. A fluoro group is particularly preferable in the halogen group. An alkoxy group having 1 to 4 carbon atoms is preferable in the alkoxy group. A phenyl group is particularly preferable in the aryl group. Iridium is particularly preferable among the elements that belong to Group 9, and platinum is particularly preferable among the elements that belong to Group 10. The general formula (1) is inserted.
US08389131B2	Material for use in phosphorescent device and organic electroluminescent device using same Provided is an organic electroluminescent device (organic EL device), in which the luminous efficiency of the device is improved, driving stability is sufficiently ensured, and the construction of the device is simple. This organic EL device is an organic electroluminescent device, including a light-emitting layer between an anode and a cathode laminated on a substrate, in which the light-emitting layer contains a phosphorescent light-emitting dopant and an indolocarbazole compound as a host material. Examples of the indolocarbazole compound include a compound represented by the following formula (1). It should be noted that in the formulae: a ring A and a ring B are represented by the formulae (1a) and (1b), respectively; Ar's each represent an aromatic hydrocarbon group or an aromatic heterocyclic group; R's each represent a hydrogen atom, an alkyl group, or a cycloalkyl group; X represents a methine group or a nitrogen atom; A represents an aromatic hydrocarbon group, an alkyl group, a cycloalkyl group, or a group represented by the formula (1c); and n represents 0 or 1.
US08389130B2	Opto-electrical polymers and devices A polymer for use in an opto-electrical device comprising aromatically conjugated repeat units of optionally substituted 9,9-dimethylfluorene.
US08389129B2	Low-friction surface coatings and methods for producing same A coated article system includes a substrate and a surface coating on the substrate. The surface coating is formed by depositing individual particles of a composite metal powder with sufficient energy to cause the composite metal powder to bond with the substrate and form the surface coating. The composite metal powder includes a substantially homogeneous dispersion of molybdenum and molybdenum disulfide sub-particles that are fused together to form the individual particles of the composite metal powder.
US08389127B2	Hot formed part, and method of making a hot formed part A hot formed part of high-strength steel includes a body having an opening and formed in one piece with at least one tab in the form of a tongue projecting into the opening for holding a connection piece captive on the body. The tab thus is formed in one piece with the hot formed part and is produced jointly with the openings during manufacture of the hot formed part in the hot forming process.
US08389118B2	Cosmetic Provided is a cosmetic including silicone microparticles, in which the silicone microparticles include 100 parts by mass of silicone elastomer spherical microparticles having a volume average particle diameter within a range from 0.1 to 100 μm, and 0.5 to 25 parts by mass of a polyorganosilsesquioxane that coats a surface of the silicone elastomer spherical microparticles, and the silicone elastomer is capable of absorbing not less than 30 parts by mass of at least one oily substance selected from the group consisting of sebum, hydrocarbon oils and ester oils per 100 parts by mass of the silicone elastomer. Even if containing an unctuous agent, the cosmetic exhibits favorable feelings upon use, with no spreading difficulties, stickiness, greasiness, oily film feeling, or the like, and is also capable of suppressing problems caused by sebum, namely, changes in the makeup cosmetic properties of the cosmetic, changes in the color of the cosmetic, increased shine, and the like.
US08389112B2	Method for producing a composite panel A method for producing a panel made of a composite material of substantially three layers including a first cover layer and a second cover layer, at least one of which cover layers is made of glass, and an intermediate layer of a synthetic resin, into which a decorative material which differs from the synthetic resin has been embedded. The method comprises the steps of providing a mesh having an upper side covered with discrete particles, adhering the underside of the mesh to a surface of the first cover layer, applying a liquid synthetic resin to the discrete particles and the mesh, applying the second cover layer on the liquid synthetic resin while the edges are sealed, and curing the liquid synthetic resin.
US08389110B2	Compositions for preparing plant fiber composites and plant fiber composites prepared from the same Provided is a composition for preparing plant fiber composite has, by weight based on the whole composition: a plant fiber raw material in an amount ranging from 60% to 80%; a starch auxiliary in an amount ranging from 10% to 30%; and a biological polymer additive in amount ranging from 10% to 20%, wherein the biological polymer additive includes a plant hormone, an enzyme, a vinegar and an ester of lactic acid. Plant fiber composite prepared from the composition is also provided. The plant fiber composite is derived from recycled material for extrusion and modeling, as a non-toxic and harmless raw material with high utilizing rate of recycled material and substitutes for plastic materials. The plant fiber composite is applied to food container, packing materials for electronic device and agricultural products, seedling trays, or substitutes for timber in the field of building, decoration and furniture.
US08389109B2	Monolithic building element with photocatalytic material A building element selected from a roofing tile or siding element may be formed from a first cementitious mixture and a second cementitious mixture containing a photocatalytic cementitious mixture. The first cementitious mixture and the photocatalytic cementitious mixture may be co-formed into a shaped uncured two layer monolith having a base layer of the first cementitious mixture and a top layer of the photocatalytic cementitious mixture. The shaped uncured two layer monolith is then cured. The resulting building element may be algae-resistant.
US08389106B2	Articles for high temperature service Articles coated via a plasma spray process, and methods for making such articles, are presented. For example, one embodiment is an article comprising a substrate comprising a top surface and a channel disposed in the substrate. The channel is defined by an internal channel surface disposed beneath the top surface and having a terminal end at an orifice at the top surface. A coating is disposed on the top surface and on at least a portion of the internal channel surface. A coating thickness at any point on the internal channel surface is less than a nominal coating thickness on the top surface, and the coating comprises a plurality of at least partially melted and solidified particles.
US08389105B2	One-dimensional continuous molded element A molded fibrous structure comprising a continuous molded element. The continuous molded element may be one-dimensional. A method for making a molded fibrous structure comprising a continuous molded element. A substrate for use as a wipe made from a molded fibrous structure.
US08389104B2	Composite cores and panels A composite core panel has opposite side surfaces for receiving skins to form a composite sandwich panel. The core panel includes a plurality of spaced blocks of low density cellular material such as foam plastics and have opposite side surfaces forming the side surfaces of the core panel and opposite edge surfaces extending between the side surfaces. A plurality of parallel spaced elongated primary strips of structural cellular material such as balsa wood or engineered foam have a higher density and extend between the blocks, and the blocks have side surfaces adhesively attached to edge surfaces of the blocks. A plurality of parallel spaced secondary strips of structural high density cellular material such as balsa wood or engineered foam extend transversely to the primary strips and have end surfaces adhesively attached to the primary strips and side surfaces adhesively attached to the blocks.
US08389102B2	Gripping area for a working device The present invention relates to a gripping area and a surface structure for a working device. In particular, the invention relates to a surface structure for a working device, which has at least one curved surface, on which there is a first surface normal and a second surface normal, which forms an α angle, wherein the surface structure comprises a base structure, which has a base surface and at least one side surface, wherein the side surface, along with the base surface, forms a β angle, and wherein the surface normal of the base surface of the base structure is parallel to the first surface normal, wherein the surface structure further comprises a variant structure, which comprises a base surface and at least one side surface, wherein a γ angle is formed between the base surface and the side surface, wherein the variant structure is different from the base structure and wherein the surface normal of the base surface of the variant structure is parallel to the second surface normal, and the γ angle is smaller than the β angle by at least the amount of the α angle. The invention also relates to a working device with such a surface.
US08389100B2	Temperature responsive smart textile A textile fabric has at least one raised surface incorporating multicomponent fibers formed of at least a first polymer and a second polymer disposed in side-by-side relationship. The first polymer and the second polymer exhibit differential thermal elongation, which causes the multicomponent fibers to bend or curl and reversibly recover in response to changes in temperature, thereby adjusting insulation performance of the textile fabric in response to ambient conditions.
US08389099B1	Asymmetrical wafer configurations and method for creating the same The present invention consists of a method for imparting asymmetry to a truncated annular wafer by either rounding one corner of the orientation flat, or rounding one corner of a notch. This novel method of rounding corners impart a visual and/or tactile asymmetry which can be utilized by a person in order to differentiate between the two different sides of the wafer. This inventive wafer design and method for making an asymmetric wafer is especially useful in the field of semiconductor technology and may be used on sapphire crystal wafers or any other class of wafer.
US08389098B2	Optical information recording medium and recording/reproducing method therefor An optical information recording medium in which recorded information is stably stored for long time in the initial state, signals are not deteriorated by a laser beam for reproduction at the time of signal reproduction, the quality does not change in normal long-term storage, the write characteristic is held, a manufacturing cost is reduced, a margin in the manufacture process is assured, and excellent recording/reproducing characteristics are obtained in the wide range of linear speeds and recording powers is provided. An optical information recording medium 1 is formed by sequentially stacking a first information recording layer 11, an intermediate layer 12, a second information recording layer 13, and a protection layer 14 on a substrate 10. As a material of a recording layer 13b of the second information recording layer 13, a material having a composition expressed by [(ZnS)x(SiO2)1-x]y(SbzX1-z)1-y (where 0
US08389097B2	Optical storage medium comprising a super-resolution structure with grainy impurities of a dielectric material The optical storage medium comprises a substrate layer, a read-only data layer with a pit structure disposed on the substrate layer, a cover layer and a nonlinear layer with a super-resolution structure disposed between the data layer and the data layer, which super-resolution structure includes a semiconductor material and grainy impurities of a dielectric material, wherein the semiconductor material has an increased reflectivity, when irradiated with a laser beam, and wherein the dielectric material is arranged as a dielectric layer having a thickness below 5 nm. The dielectric material consists advantageously of an inhomogeneous layer of a nitride material, for example GeN, arranged between a first and a second nonlinear layer.
US08389082B2	Fuel system having excellent gasoline barrier property Provided is a fuel system comprising a fuel vessel, molded parts for the fuel vessel and/or a tube for a fuel in which bodies are constituted from a thermoplastic resin and/or a rubber, wherein a coating layer is formed on the surfaces in at least one sides of the insides and the outsides of the fuel vessel body, the molded part bodies for the fuel vessel and/or the tube body for a fuel or at least one of connected parts with these bodies; the above coating layer is formed by curing an epoxy resin composition comprising an epoxy resin and an epoxy resin curing agent as principal components; and the above coating layer has a gasoline permeability coefficient of 2 g·mm/m2·day or less at 23° C. and a relative humidity of 60% RH. The above coating layer is excellent in a permeation-preventing performance against an automobile fuel (gasoline barrier property), a heat resistance and an impact resistance, then a fuel vessel, molded parts for the fuel vessel and a tube which have excellent performances are obtained.
US08389078B2	Three-dimensional effect printing method and electronic device treated using the method An electronic device includes a housing. The housing includes a transparent substrate, a transparent texture layer, and a colored texture layer. The transparent texture layer is printed on the inner surface of the transparent substrate and has an uneven surface. The colored texture layer is printed on the uneven surface of the transparent texture layer. A three-dimensional effect printing method is also provided.
US08389073B2	Four-ring liquid crystal compound having tetrahydropyran and 2,2′,3,3′-tetrafluorobiphenyl, liquid crystal composition and liquid crystal display device The invention provides a liquid crystal compound that has a large negative dielectric anisotropy (Δ∈) and also has at least one of characteristics such as the stability to heat, light or the like, a high clearing point, a suitable refractive index anisotropy (Δn), a large negative dielectric anisotropy (Δ∈) and an excellent compatibility with other liquid crystal compounds. An excellent effect in which especially the value of the dielectric anisotropy (Δ∈) is increased negatively is achieved by use of the compound having two moieties of 1) a tetrahydropyran ring and and thus the effect is utilized.
US08389072B2	System, method, and apparatus for variable hardness gradient armor alloys A variable hardness gradient armor alloy is produced with a liquid-state reaction between a metallic molten pool and a gaseous atmosphere having a small fraction of reactive gas. The content of the reactant gas is varied as the armor is fabricated in order to vary the properties of the resultant material across its thickness and typically include, for example, a hardened outer or initial layer for impact resistance, and at least one inner layer having a lower hardness than the outer layer but greater energy absorption.
US08389070B2	Coating of a polymer layer using low power pulsed plasma in a plasma chamber of a large volume A method for depositing a polymeric material onto a substrate, said method comprising introducing an organic monomeric material in a gaseous state into a plasma deposition chamber, igniting a glow discharge within said chamber, and applying a high frequency voltage as a pulsed field, at a power of from 0.001 to 500 w/m3 for a sufficient period of time to allow a polymeric layer to form on the surface of the substrate. The method is particularly suitable for producing oil and water repellent coatings, in particular where the monomeric material contains haloalkyl compounds. Apparatus particularly adapted to carry out the method of the invention is also described and claimed.
US08389069B2	Method for marking an item based on colour centres The invention relates to a method for marking an item based on the formation of color centers on a lithium fluoride film. The method provides for the deposition of thin LiF films on the item or on mark supports to be applied to the item and the formation of the color centers by irradiation, thus forming an identification mark. Optionally, the method may provide for the detection of the identification mark and the control of its authenticity. The method may be employed both to guarantee the authenticity of the item and to classify it. The application of the method is particularly advantageous in the field of high value goods and specifically in the field of cultural objects.
US08389067B2	Deposition of lubricant onto magnetic media Disclosed herein are methods that include inserting a magnetic media into an enclosure and using a non-thermal physical vapor deposition process to deposit a lubricant onto the magnetic media within the enclosure. Also disclosed are methods that include loading a magnetic media that includes a tribological coating into an enclosure and using an electrospray ionization process to deposit a lubricant onto the magnetic media within a vacuum created by the enclosure.
US08389063B2	Barrier-coating layer application method A method for spray-creating a composite-material layer on the outside surface of a liquid container to defeat liquid leakage following a projectile penetration of the container. The method includes (a) defining a by-weight percentage blend of two penetration-reaction materials, where the contribution of one such material, an initially liquid and wet-sprayable, but subsequently curable-to-dry, high-elastomeric body-forming material, is larger than that of the other material, which takes the form of a population of dry, liquid-imbibing bead elements, (b) creating weight-percentage-differentiated, simultaneous sprays of these two materials for contact-blending, during spraying, into a composite spray en route in the air toward the region of a target liquid container, and (c) as a part of such creating, controlling the amount of en route, inter-material, contact blend time between the two materials.
US08389061B2	Aqueous emulsion polymer for scrub resistance and wet adhesion An aqueous emulsion polymer and a method for preparing the aqueous emulsion polymer, where the aqueous emulsion polymer is useful in an aqueous coating composition to provide good scrub resistance while maintaining wet adhesion of the aqueous coating composition.
US08389059B2	Surface treatment of amorphous coatings A method to improve corrosion, abrasion, resistance to environmental degradation and fire resistant properties of structural components for use in oil, gas, exploration, refining and petrochemical applications is provided. The structural component is suitable for use as refinery and/or petrochemical process equipment and piping, having a substrate coated with a surface-treated amorphous metal layer. The surface of the structural component is surface treated with an energy source to cause a diffusion of at least a portion of the amorphous metal layer and at least a portion of the substrate, forming a diffusion layer disposed on a substrate. The diffusion layer has a negative hardness profile with the hardness increasing from the diffusion surface in contact with the substrate to the surface away from the substrate.
US08389056B1	Decorative engineered bamboo products and method of manufacturing Decorative engineered bamboo product and a method of forming a decorative engineered bamboo product in which a block of engineered bamboo product is sliced to expose an edge grain formed by edges of strands of bamboo of the product. The slices can be used directly or attached to a substrate. The slices can be further treated to produce additional decorative features. Additives can be introduced to the engineered bamboo product during the manufacture thereof to incorporate decorative elements therein which are made visible by slicing the engineered bamboo product to expose edge grain, inclusive of the cross-section of the additives.
US08389053B2	Method of cleaning powdery source supply system, storage medium, substrate processing system and substrate processing method A method of cleaning a powdery source supply system prevents outflow of particles from a chamber or an introduction line in a film forming process. A substrate processing system includes a powdery source supply system and a film forming processing unit. The powdery source supply system includes an ampoule for accommodating a powdery source, a carrier gas supply unit for supplying a carrier gas into the ampoule, an introduction line for connecting the ampoule and the film forming processing unit, a purge line branched from the introduction line, and a valve for opening or closing the introduction line. When the valve is opened and the interior of the purge line is evacuated prior to the film forming process, the carrier gas supply unit supplies a carrier gas so that the viscous force acting on particles by the carrier gas is greater than the viscous force in the film forming process.
US08389052B2	Method for treating inside surface of glass container and glass container A method for treating the inside surface of a glass container includes applying a polysilazane solution to the inside surface of the glass container, drying the polysilazane while the glass container is rotated in the state of being inverted and inclined 50° to 70° with respect to horizontal, and sintering the polysilazane. During the sintering, the sintering temperature is 300° C. to 600° C. and the sintering time is 10 minutes or more. The method may also include applying at least one of a sulfur dioxide gas, a sulfur trioxide gas, a chlorine gas, and a chlorofluorocarbon gas to the inside surface of the glass container under heating, during which the average temperature of the glass container may be 500° C. to 700° C.
US08389046B2	Liquid material arrangement method, color filter manufacturing method, and organic EL display device manufacturing method A liquid material arrangement method includes a first patter generating step, a dot deleting step and a liquid material arranging step. In the first pattern generating step, a first dot pattern is generated in which a first prescribed number of dots is set. In the dot deleting step, a second prescribed number of dots is deleted to generate a second dot pattern. In the liquid material arranging step, a liquid material is arranged in the prescribed region on the substrate by causing a nozzle and the substrate to scan in relative manner and discharging the liquid material based on the second dot pattern. In the dot deleting step, a dot indicator for each the first prescribed number of dots is determined based on discharge information of the nozzle, and the second prescribed number of dots is deleted based on the dot indicator.
US08389045B2	Method for producing oxide superconductor An oxide superconductor film formed on a substrate includes an oxide containing at least one metal M selected from the group consisting of yttrium and lanthanoid metals, provided that cerium, praseodymium, promethium and ruthenium are excluded, and barium and copper, in which the film has an average thickness of 350 nm or more, an average amount of residual carbon of 3×1019 atoms/cc or more, and an amount of residual fluorine in a range of 5×1017 to 1×1019 atoms/cc, and in which, when divided the film into a plurality of regions from a surface of the film or from an interface between the film and the substrate, each region having a thickness of 10 nm, atomic ratios of copper, fluorine, oxygen and carbon between two adjacent regions are in a range of ⅕ times to 5 times.
US08389041B2	Systems and methods for rotating and coating an implantable device A method for applying a coating to an implantable device is disclosed. The method includes positioning an implantable device relative to an ultrasonic material delivery apparatus. The implantable device is rotated at a relative speed. The relative speed may be more than 120 revolutions per minute. An application material is applied to the implantable device using the ultrasonic material delivery apparatus. The relative speed may be sufficient to reduce the size of at least a portion of droplets of the application material. A system for rotating an implantable device is disclosed. The system includes an implantable device and a rotation system configured to rotate the implantable device. A longitudinal axis of the implantable device and a longitudinal axis of a rotation member of the rotation system may be offset a desired dimension. An inside diameter of the implantable device may be larger than an outside diameter of a rotation member.
US08389040B2	Production of acid soluble soy protein isolates (“S700”) A soy protein product having a protein content of at least about 60 wt % (N×6.25) d.b., preferably an isolate having a protein content of at least about 90 wt % (N×6.25) d.b., is formed by extracting a soy protein source with a salt solution, preferably aqueous sodium chloride solution, to form an aqueous protein solution having a pH of about 1.5 to 11, preferably about 5 to about 7 and separating the resulting aqueous protein solution from residual soy protein source. The protein concentration of the aqueous protein solution is increased to about 50 to about 400 g/L while the ionic strength is maintained substantially constant by using a selective membrane technique. The resulting concentrated protein solution is optionally diafiltered and a calcium salt, preferably calcium chloride, is added to the concentrated and optionally diafiltered protein solution to a conductivity of 15 to about 85 mS. Precipitate formed as a result of the calcium salt addition is removed and the resulting clarified retentate is diluted into about 2 to about 20 volumes of water prior to acidification to a pH of about 1.5 to about 4.4 to produce an acidified clear protein solution. The acidified clear protein solution is then concentrated and optionally diafiltered and optionally dried. Variations of this procedure can be used to produce a soy protein product which is soluble, transparent and heat stable in acidic aqueous environments.
US08389031B2	Coated delivery system for active components as part of an edible composition A delivery system for inclusion in an edible composition is formulated to have at least one active component with an encapsulating material for delivering the active component upon consumption of the edible composition.
US08389030B2	Nematicides from Juglandaceae and methods of use thereof The invention provides compositions and methods for inhibiting nematode damage to plants. The compositions comprise acid extracts or alcohol extracts from juglone-producing members of the Juglandaceae. The methods comprise applying the compositions of the invention to soil contacting roots of nematode-susceptible plants.
US08389029B2	Deterioration smell inhibitor and antimicrobial The object of the present invention is to provide a deterioration smell inhibitor capable of effectively inhibiting deterioration smell generating form various products such as foods and cosmetics. The present invention relates to a deterioration smell inhibitor comprising a plant extract and isothiocyanate. As preferred embodiments, the plant extract is a labiatae plant extract, further the labiatae plant extract is an oil-insoluble labiatae plant extract, still further the weight ratio of the oil-insoluble labiatae plant extract/isothiocyanate is 1/1 to 99/1. In other preferred embodiments, the plant extract is a terpenoid alcohol or terpenoid ketone, further the weight ratio of the terpenoid alcohol or terpenoid ketone/isothiocyanate is 0.4/1 to 40/1.
US08389028B2	Method for promoting eye health The present invention relates to a method for promoting eye health by administering to a companion animal a composition comprising at least one polyphenol selected from the group consisting of rosemary, rosemary extract, coffeic acid, coffee extract, turmeric extract, cucurmin, blueberry extract, grapeseed extract, rosemarinic acid, tea extract, and mixtures thereof.
US08389027B2	Digoxin-like fungal glycoside with cytotoxic properties: novel assay and applications The present invention provides methods of isolating cytotoxic metabolites from a fungus, and specific metabolites obtained from such methods. The present invention also provides methods of controlling fungal diseases in plants by treating the plants with cytotoxic metabolites as well as methods of treating cardiac arrhythmia in organisms in need of such treatment by administering the above-noted metabolites to such organisms.
US08389026B2	Composition and method for skin repair A composition and a method of using the composition is described that is effective to protect or repair oxidative damage to DNA in mammalian skin by up regulating each of SIRT1, Gadd45b, and SOD2. The composition includes at least two of a candle bush extract, noni leaf extract, and melon extract with each present in an amount such that the composition is effective to up regulate each of SIRT1, Gadd45b, and SOD2.
US08389024B2	Abscisic acid against cancer ABSCISIC Acid (ABA) a naturally occurring plant hormone has been identified in this invention with potent properties to fight cancer. ABA is able to produce a hyperpolarization condition on plasma membrane through a decrease of intracellular Na+ and K+. Such phenomenon is produced in cancer cells by mediation of ion channel and activation of the signaling g-protein pathway. ABA aborting sustained depolarization in malignant tissue will produce a change in the configurational state of cell from a damage to a normal state. additionally, a positive polarization of hCG outer layer accomplished through a removal of electrons will permit immune system cells coming close to cancer cells for destruction.
US08389022B2	Material, item and products comprising a composition having anti-microbial properties A coating product composition has the general formula AOx-(L-Men+)i, wherein AOx is a metal or metalloid oxide in which x indicates the number of the Oxygen atom(s) (O) bonded to the metal (A) atom, Men+ is a metal ion, L is a bifunctional molecule that could bind both metal oxide or metalloid oxide (AOx) and the metal ion (Men+), i is the number of the (L-Men+) groups bound to the metal oxide AOx. The value of the parameter i depends on various factors, such as the size of the nanoparticle of AOx, and the nature of the molecule L.
US08389020B1	Immediate action and long-lasting formulation to control moss and liverwort Ferrous sulfate and ferrous ammonium sulfate are known to kill moss and liverwort. They impart acidity in the lawn. Moss grows better in an acidic pH. The current invention proposes a formulation of ferrous sulfate or ferrous ammonium sulfate and zero valent iron with lime. Lime neutralizes the acidity produced by the ferrous salt and keeps the pH of the soil at 7 to 7.5. The formulation produces an immediate effect to eradicate moss and also provides a sustained effect over a long period. Another embodiment contains an addition of antimicrobial agents such as benzalkonium chloride, dichlorophen, and didecyldimethyl ammonium chloride to the ferrous sulfate-lime formulation.
US08389017B1	Calcium-containing structures and methods of making and using the same The present invention generally relates to calcium-containing structures and methods of making and using the structures. In one aspect, hollow calcium containing microstructures are used in conjunction with bone tissues/by-products to augment bone defects and extend the supply of bone tissues/by-products for bone augmentation. Bonding agents, such as calcium cements, are also used in the preparation of the hollow calcium microstructures combined with bone tissues/by-products or for use in preparing the hollow microstructures. The calcium-containing microstructures of the present invention are also useful as delivery vehicles of nitric oxide and/or nitric oxide containing or producing compounds for a variety of in vitro and in vivo uses. Calcium containing contoured substrates upon which cells/tissues can be grown in vitro for replacement and repair of tissues in vivo that conform in size and shape to the tissue surface to be replaced are also provided.
US08389015B2	Salivary bioassay for early detection of bone loss The present invention is directed to methods to detect and diagnose osteoporosis and periodontal disease using salivary biomarkers.
US08389014B2	Gel useful for the delivery of ophthalmic drugs The present invention relates to a solid powder composed of a mixture of a natural or a synthetic polymer which forms a gel, a buffer, such as an hydroxyacid or a dicarboxyacid, a saccharide, one or more drugs useful for the treatment of diseases of the eyes and optionally one or more excipients and/or regulators of the osmotic pressure ophthalmologically acceptable.
US08389011B2	Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors A pharmaceutical composition comprises a solid amorphous dispersion of a cholesteryl ester transfer protein inhibitor and a concentration-enhancing polymer.
US08389008B2	Delayed release dosage forms A delayed release pharmaceutical formulation comprising a core containing an active agent (e.g., a drug) and a delayed release compression coating comprising a natural or synthetic gum applied onto the surface of the core.
US08389007B2	Pharmaceutical composition containing gelling agent Disclosed in certain embodiments is a controlled release oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse together with one or more pharmaceutically acceptable excipients; the dosage form further including a gelling agent in an effective amount to impart a viscosity unsuitable for administration selected from the group consisting of parenteral and nasal administration to a solubilized mixture formed when the dosage form is crushed and mixed with from about 0.5 to about 10 ml of an aqueous liquid; the dosage form providing a therapeutic effect for at least about 12 hours when orally administered to a human patient.
US08389004B2	Process for producing protein microparticles The present invention relates to a process for producing protein microparticles in dilute organic acid solutions and in the absence of an alcohol such as ethanol. The microparticles are formed by dissolving a cereal prolamin protein in a concentrated organic acid solution with agitation and then diluting the solution with an aqueous solution. Protein microparticles having vacuoles are thus formed. The protein microparticles may be used to form powders, films, coatings, matrices, scaffolds and the like. Complete films can be formed from the protein microparticles of the invention.
US08389002B2	Anti-cancer medicine both for diagnosing and treating cancer Disclosed is an anti-cancer medicine comprising a chain end functionalized polymer, a contrast material such as iron oxide and a chemotherapeutic agent such as doxorubicin or pharmaceutically acceptable salts thereof. The anti-cancer medicine performs diagnosis and treatment of cancer at the same time, remarkably reduces a cardiotoxic side effect of the doxorubicin and has an excellent targeting function to the cancer part to considerably increase the anti-cancer effect. At the same time, the anti-cancer medicine is provided as MRI contrast medium which can diagnose the cancer and monitor a progress of the disease. In particular, the anti-cancer medicine is disclosed which is superior to the diagnosis and treatment of the solid cancer and can effectively perform the diagnosis and treatment of the metastatic cancer as well as the primary cancer at the same time.
US08389000B2	Adhesive skin patch and method for evaluation of adhesive skin patch Disclosed is an adhesive skin patch having an SIS block copolymer as an adhesive component, which has an improved handling property and can reduce irritation to a user. The adhesive skin patch comprises a flexible substrate and an adhesive layer laminated on the substrate, wherein the adhesive layer comprises a styrene-isoprene-styrene block copolymer. In the adhesive skin patch, the tan δ value of the adhesive agent as determined by measuring a dynamic viscoelasticity at 32° C. satisfies a requirement represented by the following formula 1 at at least one frequency laying between 0.04 to 0.25 Hz. 0.25x+0.05≦y≦0.25x+0.10 (formula 1) [wherein x represents a frequency (Hz); and y represents a tan δ value.]
US08388999B2	Methods and compositions for the prevention and treatment of inflammatory diseases The invention provides compositions for preventing or treating inflammatory disease comprising one or more omega-3 fatty acids, one or more sulfur containing amino acids, and manganese and methods for preventing and treating inflammatory disease comprising administering such compositions to an animal susceptible to or suffering from inflammatory disease. In a preferred embodiment, the composition is admixed with one or more food ingredients to produce a food composition useful for preventing or treating inflammatory disease.
US08388998B2	Methods and compositions for the prevention and treatment of inflammatory diseases The invention provides compositions for preventing or treating inflammatory disease comprising one or more omega-3 fatty acids, one or more sulfur containing amino acids, and manganese and methods for preventing and treating inflammatory disease comprising administering such compositions to an animal susceptible to or suffering from inflammatory disease. In a preferred embodiment, the composition is admixed with one or more food ingredients to produce a food composition useful for preventing or treating inflammatory disease.
US08388997B2	Method of preparing an unsaturated fatty acid dry concentrate There is provided a method of preparing an unsaturated fatty acid dry concentrate, wherein a substance comprising at least one unsaturated fatty acid is applied on a biologically inert matrix having a large surface area and is subsequently dried, as well as a composition comprising at least one unsaturated fatty acid and foods, beverages, drugs comprising this composition.
US08388996B2	Methods of manufacturing a medicated tampon assembly A method is provided for manufacturing a medicated tampon assembly having a tampon body, the method including applying a formulation including a therapeutic agent to a substrate to produce a plurality of dosage forms; separating one of the dosage forms from the substrate; and coupling one of the dosage forms to the tampon body. A medicated tampon assembly is provided including a dosage form including a formulation including a therapeutic agent; a substrate portion separated from a substrate, wherein the substrate portion is coupled to the dosage form; and a tampon body having a distal end, wherein the substrate portion is coupled to the distal end of the tampon body.
US08388993B2	Hyaluronan-chemotherapeutic agent formulations for the treatment of colon cancer The present invention relates to the enhancement of bioavailability of chemotherapeutic agents for the treatment of disease. In particular, the present invention relates to a method of enhancing the bioavailability of a chemotherapeutic agent comprising the step of administering to a subject in need thereof a therapeutically effective amount of hyaluronan.
US08388991B2	Moisturizing antimicrobial composition An antimicrobial moisturizing composition includes benzethonium chloride or benzalkonium chloride, a non-benzyl cationic surfactant, and an aqueous carrier. The composition of the present invention provides a significant and unexpected reduction of irritation, inflammation, dryness and/or redness, all issues associated with known alcohol-based skin disinfectants. In particular, the present invention provides a stable, aesthetically-pleasing, long-lasting, and moisturizing antimicrobial composition that is substantially free of ethanol, polysorbates, and anionic compounds that are known to inhibit the activity of benzethonium chloride or benzalkonium chloride.
US08388989B2	Articles of clothing treated with ammonia oxidizing bacteria to produce nitric oxide Articles of clothing treated with bacteria adapted to metabolize a component selected from the group consisting of ammonia, ammonium salts, or urea into any of nitric oxide, nitric oxide precursors, and combinations thereof are provided.
US08388985B2	Easily dispersible lipidic phase The present invention relates to the use of a lipidic phase comprising an oil and a lipophilic additive (LPA), which is suitable to make an oil-in-water emulsion by application of low energy or a manual operation. The lipidic phase contains a Lipophilic Additive (LPA) which forms self-assembly structures inside the emulsion oil droplets. The aqueous phase contains a hydrophilic emulsifier and the lipidic and aqueous phases are mixed without using classical high shearing devices or homogenisers.
US08388979B2	Polypeptide having affinity for envelope virus constituent and use thereof in transferring substance into cell Delivery proteins are provided for transferring a protein, antibody or foreign substance into a cell without impairing the function or structure thereof. Further, methods of transferring a foreign substance into a cell at a high efficiency by using the delivery protein or an envelope virus or inactivated envelope virus in combination with said delivery protein are provided. The inventors discovered that a protein containing a polypeptide having an affinity for a constituent of the envelope virus contributes to the efficient enclosure of the foreign substance in the envelope. Moreover, the inventors discovered that use of the delivery protein enables foreign substances to be included in an envelope virus or inactivated envelope virus and therefore makes it possible to efficiently transfer the substances into cells without damaging the physiological function thereof.
US08388976B2	Polypeptide specifically binding to vascular endothelial growth factor, fusion protein including polypeptide, and methods therefor A polypeptide inhibiting binding between a vascular endothelial growth factor and a vascular endothelial growth factor receptor, a fusion protein including the same, and a method of preparing the fusion protein are disclosed.
US08388974B2	Neovascular-targeted immunoconjugates Immunoconjugates for treating diseases associated with neovascularization such as cancer, rheumatoid arthritis, the exudative form of macular degeneration, and atherosclerosis are described. The immunoconjugates typically consist of the Fc region of a human IgG1 immunoglobulin including the hinge, or other effector domain or domains that can elicit, when administered to a patient, a cytolytic immune response or cytotoxic effect against a targeted cell. The effector domain is conjugated to a targeting domain which comprises a factor VII mutant that binds with high affinity and specificity to tissue factor but does not initiate blood clotting such as factor VII having a substitution of alanine for lysine-341 or of alanine for serine-344.
US08388973B2	Compositions and methods for the treatment of tumor of hematopoietic origin The present invention is directed to compositions of matter useful for the treatment of hematopoietic tumor in mammals and to methods of using those compositions of matter for the same.
US08388972B2	Human anti-folate receptor alpha antibodies and antibody fragments for the radioimmunotherapy of ovarian carcinoma Antibody or fragment thereof, which specifically binds to folate receptor-alpha (FRα), wherein said antibody or fragment thereof comprises a light chain whose variable region comprises at least one of the following amino acid sequences: —RASESVSFLGINLIH (SEQ ID NO: 3), —QASNKDT (SEQ ID NO: 4), —LQSKNFPPYT (SEQ ID NO: 5), and wherein the constant region of said light chain is a kappa constant region.
US08388971B2	Antibodies that bind CD40 and methods of treating cancer and enhancing immune responses The present invention relates to antibodies and antigen-binding portions thereof that specifically bind to CD40, preferably human CD40, and that function as CD40 agonists. The invention also relates to human anti-CD40 antibodies and antigen-binding portions thereof. The invention also relates to antibodies that are chimeric, bispecific, derivatized, single chain antibodies or portions of fusion proteins. The invention also relates to isolated heavy and light chain immunoglobulins derived from human anti-CD40 antibodies and nucleic acid molecules encoding such immunoglobulins. The present invention also relates to methods of making human anti-CD40 antibodies, compositions comprising these antibodies and methods of using the antibodies and compositions for diagnosis and treatment. The invention also provides gene therapy methods using nucleic acid molecules encoding the heavy and/or light immunoglobulin molecules that comprise the human anti-CD40 antibodies. The invention also relates to transgenic animals comprising nucleic acid molecules of the present invention.
US08388968B2	Compositions and methods for increasing muscle growth This disclosure is in the field of anti-Activin receptor IIB (ActRIIB) antibodies. In particular, it relates to the use of said antibodies for treating muscle disorders, such as muscle wasting due to disease or disuse.
US08388967B2	Methods for inducing or enhancing an immune response by administering agonistic GITR-binding antibodies The present invention provides binding molecules that specifically bind to GITR, e.g., human GITR (hGITR), on T cells and dendritic cells. Binding molecules of the invention are characterized by binding to hGITR with high affinity, in the presence of a stimulating agent, e.g., CD3, are agonistic, and abrogate the suppression of Teff cells by Treg cells. Various aspects of the invention relate to binding molecules, and pharmaceutical compositions thereof, as well as nucleic acids, recombinant expression vectors and host cells for making such binding molecules. Methods of using a binding molecule of the invention to detect human GITR or to modulate human GITR activity, either in vitro or in vivo, are also encompassed by the invention.
US08388966B2	Combination treatment of pancreatic cancer A combination for use in the treatment of pancreatic cancer comprising: (i) an anti-gastrin effective immunogenic composition; and, (ii) one or more chemotherapeutic agents suitable for inhibiting cancer growth.
US08388957B2	Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors The present invention provides diagnostic and prognostic methods for predicting the effectiveness of treatment of a cancer patient with an IGF-1R kinase inhibitor. Methods are provided for predicting the sensitivity of tumor cell growth to inhibition by an IGF-1R kinase inhibitor, comprising assessing whether the tumor cell has undergone an epithelial to mesenchymal transition (EMT), by determining the expression level of epithelial and/or mesenchymal biomarkers, wherein tumor cells that have undergone an EMT are substantially less sensitive to inhibition by IGF-1R kinase inhibitors. Improved methods for treating cancer patients with IGF-1R kinase inhibitors that incorporate the above methodology are also provided.
US08388956B2	Interleukin-1 alpha antibodies and methods of use Fully human monoclonal Abs includes (i) an antigen-binding variable region that exhibits very high binding affinity for IL-1α and (ii) a constant region that is effective at both activating the complement system though C1q binding and binding to several different Fc receptors.
US08388954B2	Stabilising formulation for immunoglobulin G compositions in liquid form and in lyophilised form This invention is related to a stabilizing formulation for immunoglobulins G compositions comprising a sugar alcohol, glycine and a non-ionic detergent, which is suitable for the stabilization of immunoglobulins G compositions in liquid form and in lyophilized form. The invention also relates to an immunoglobulins G composition in liquid form or in lyophilized form comprising said stabilizing formulation.
US08388946B2	Bacteriophage-containing therapeutic agents The present invention relates in its broadest aspect to combined phage/antibiotic therapy. More particularly, it relates to use of (i) one or more bacteriophages and (ii) one or more antibiotics in the manufacture of a combined product for simultaneous, separate or sequential administration of (i) and (ii) to treat a bacterial infection characterized by biofilm formation, for example an infection comprising or consisting of P. aeruginosa. Treatment in this context may be either therapeutic or prophylactic treatment. Also provided are deposited bacteriophages each exhibiting different strain specificity against P. aeruginosa and combinations of such bacteriophages, e.g. a panel of six deposited bacteriophages which was found to be effective against a high percentage of clinical isolates of P. aeruginosa from canine ear infections.
US08388943B2	Multipotent stem cells from peripheral tissues and uses thereof This invention relates to multipotent stem cells, purified from the peripheral tissue of mammals, and capable of differentiating into neural and non-neural cell types. These stem cells provide an accessible source for autologous transplantation into CNS, PNS, and other damaged tissues.
US08388942B2	Methods of interferon-β purification and recovery Improved methods for purification and recovery of interferon-beta (IFN-β) and compositions comprising substantially monomeric IFN-β are provided. In one purification method, substantially purified IFN-β or variant thereof is precipitated and then dissolved in a guanidine hydrochloride (HCl) solution. Renaturation of the protein occurs by dilution with a suitable buffer. A similar purification method absent the precipitation step is also provided. Following renaturation of the IFN-β, residual guanidine HCl is removed by diafiltration or dialysis with a pharmaceutically acceptable buffer to prepare pharmaceutical compositions comprising substantially monomeric IFN-β.
US08388941B2	Self preserved aqueous pharmaceutical compositions The use of a borate/polyol and zinc system to enhance the antimicrobial activity of multi-dose pharmaceutical compositions is described. The compositions do not require a conventional anti-microbial preservative and therefore are referred to as being ‘self-preserved’. The compositions possess sufficient antimicrobial activity to satisfy the preservative efficacy requirements of the USP for aqueous ophthalmic compositions.
US08388938B2	Solid oral tooth whitening confectionary composition The present invention provides a solid, oral tooth whitening confectionary composition comprising a tooth whitening agent comprising an alkaline or alkaline earth metal pyrophosphate, preferably calcium pyrophosphate. In one embodiment, the composition of the invention comprises an additional tooth whitening agent.
US08388931B2	99m Tc-labeled triphenylphosphonium derivative contrasting agents and molecular probes for early detection and imaging of breast tumors 99mTc-labeled triphenylphosphonium contrasting agents that target the mitochondria and are useful for early detection of breast tumors using scintimammographic imaging. 99mTc-Mito10-MAG3 possesses advantageous radiopharmaceutical properties. The uptake in the myocardium is reduced by one to two orders of magnitude compared to 99mTc-MIBI. 99mTc-Mito10-MAG3 exhibits fast blood clearance, with a blood half-life of less than 2 minutes in rats. A diminished myocardial uptake combined with a prompt reduction of cardiovascular blood pool signal to facilitate improved signal-to-background ratios.
US08388927B2	Scorodite-type iron-arsenic compound particles, production method thereof, and arsenic-containing solid Scorodite-type iron-arsenic compound particles in which the particle surface layer part comprise an iron-rich layer having an Fe/As molar ratio of at least 1.24. The particles can be obtained in a reaction process of feeding an oxygen-containing gas to an aqueous solution containing an arsenic(V) ion and an iron(II) ion to precipitate a scorodite-type iron-arsenic compound crystal at a pH of at most 2, in which an oxidizing agent is further added to the liquid before the end of the reaction (treatment A). The particles may also be obtained by a method comprising keeping a scorodite-type iron-arsenic compound particle of good crystallinity in contact with an iron ion-containing aqueous solution having a controlled pH of from 2 to 9 at 0 to 90° C. (treatment B). The scorodite-type iron-arsenic particles have good filterability and excellent arsenic release-preventing effect.
US08388925B2	Methods for producing aluminum trifluoride Methods for producing aluminum trifluoride by acid digestion of fluoride salts of alkali metal or alkaline earth metal and aluminum, optionally, in the presence of a source of silicon; methods for producing silane that include acid digestion of by-products of silane production to produce aluminum trifluoride.
US08388924B2	Method for growth of high quality graphene films The present application relates generally to methods for growth of high quality graphene films. In particular, a method is provided for forming a graphene film using a modified chemical vapor deposition process using an oxygen-containing hydrocarbon liquid precursor. Desirably, the graphene films are a single-layer and have a single grain continuity of at least 1 μm2.
US08388923B2	Combination catalysts based on iron for the substantial synthesis of multi-walled carbon nanotubes by chemical vapor deposition Methods and systems of preparing a catalyst to be used in the synthesis of carbon nanotubes through Chemical Vapor Depositions are disclosed. The method may include a mixture comprising at least one of an iron catalyst source and a catalyst support. In another aspect, a method of synthesizing multi-walled carbon nanotubes using the catalyst is disclosed. The method may include driving a reaction in a CVD furnace and generating at least one multi-walled carbon nanotube through the reaction. The method also includes depositing the catalyst on the CVD furnace and driving a carbon source with a carrier gas to the CVD furnace. The method further includes decomposing the carbon source in the presence of the catalyst under a sufficient gas pressure for a sufficient time to grow at least one multi-walled carbon nanotube.
US08388922B2	Negative electrode material for lithium battery, and lithium battery The present invention relates to a negative electrode material for a lithium battery comprising a carbonaceous negative electrode active substance having a specific surface area of 1 m2/g or more, a binder formed of styrene-butadiene rubber and a carbon fiber having a fiber diameter of 1 to 1,000 nm; and to a lithium battery using the negative electrode material, which has excellent characteristics, i.e., low electrode resistance, high electrode strength, excellent electrolytic solution permeability, high energy density, and good high-speed charging/discharging performance. The negative electrode material contains carbon fiber in the amount of 0.05 to 20 mass % and the binder formed of styrene-butadiene rubber in 0.1 to 6.0 mass %, and may further contain a thickener such as carboxymethyl cellulose in the amount of 0.3 to 3 mass %.
US08388920B2	Selective catalytic reduction via electrolysis of urea A method and apparatus for producing ammonia suitable for use as a reductant in a selective catalytic reduction (SCR), a selective non-catalytic reduction (SNCR), or a flue gas conditioning system is provided. A method for treating combustion exhaust gas with ammonia is provided that includes the electrolytic hydrolysis of urea under mild conditions. The electrolysis apparatus includes an electrolytic cell, which may be operatively coupled to an exhaust gas treatment system to provide an apparatus for reducing nitrogen oxides (NOx) and/or particulate in exhaust gases.
US08388919B2	Plant and process for removing carbon dioxide from gas streams The present invention is based on the realization that the carbon dioxide component of industrial gas streams also containing steam can be processed so to utilize either as latent and/or sensible heat the heat available from the steam component to assist in separating carbon dioxide from the remainder of the gas stream. For example, flue gases produced by power stations burning brown coal, black coal or natural gas inherently contain a useful amount of energy that can be harnessed according to the present invention. According to particular preferred forms of the invention, nitrogen and sulphur constituent such as SOx and NOx, H2S and other nitrogen containing compounds may also be removed from the gas stream through direct contact with the absorbing medium and used to produce by-products such as fertilizer material.
US08388917B2	Air pollution control system and air pollution control method An air pollution control system 10A includes a boiler 11 that burns fuel, an air heater 13 that recovers heat of flue gas 17 from the boiler 11, and a desulfurizer 15 that reduces sulfur oxides contained in the flue gas 17 after heat recovery by an absorbent, and waste-water supplying units P0 to P5 that supply desulfurized waste water 28 discharged from the desulfurizer 15 to at least one of a path for supplying fuel to the boiler 11, inside of a furnace of the boiler 11, and the inside of a flue gas duct between the boiler 11 and the air heater 13 are installed. With this configuration, an amount of desulfurized waste water to be returned into the flue gas duct per unit time can be increased as compared to conventional systems, without increasing the size of the entire air pollution control system.
US08388915B2	Basic magnesium sulfate granule having high crush strength and process for production thereof A method for producing basic magnesium sulfate granules, by heating a water-containing granular composition to a temperature of 50-250° C. to dryness. The granular composition has a water content of 10-60 wt. % and comprises fibrous basic magnesium sulfate particles, magnesium hydroxide in an amount of 5-300 weight parts per 100 weight parts of the fibrous basic magnesium sulfate particles, magnesium sulfate in an amount of 0.1-200 weight parts per 100 weight parts of a total amount of the fibrous basic magnesium sulfate particles and magnesium hydroxide. This method can give basic magnesium sulfate granules having a low bulk density and a high crushing strength.
US08388914B2	Systems for producing silane Methods and systems for producing silane that use electrolysis to regenerate reactive components therein are disclosed. The methods and systems may be substantially closed-loop with respect to halogen, an alkali or alkaline earth metal and/or hydrogen.
US08388913B2	Reagent container system A reagent container system for a reagent analyzer, in particular an automatic reagent analyzer, is disclosed. The system includes a first reagent container cassette provided with a first set of openings each being capable of containing a reagent therein, and a second reagent container cassette provided with a second set of openings each being capable of containing a reagent therein. The system provides the first and second reagent container cassettes at least in a storage configuration in which the container cassettes are joined together such that a longitudinal side of the first reagent container cassette is facing a longitudinal side of the second reagent container cassette. Wherein, by relative displacement, the first and second reagent container cassettes are displaceable between the storage configuration and a use configuration in which a transverse side of the first reagent container cassette is facing a transverse side of the second reagent container cassette.
US08388912B2	Temperature transfer devices A portable temperature transfer device for transferring thermo energy to and/or from a laboratory culture plate is provided as well as its methods of use. The temperature transfer device comprises a base and a raised stage that comprises a thermal conductive material. The raised stage allows direct contact between individual wells of the laboratory culture plate and the temperature transfer device.
US08388908B2	Fluidic devices with diaphragm valves This invention provides fluidic devices, in particular microfluidic devices, with diaphragm valves having low failure rates. Low failure rates are achieved by inhibiting sticking of the diaphragm to functional surfaces such as valve seats, valve chamber and fluidic channels and conduits. One way to implement this is to provide exposed surfaces facing the diaphragm, particularly valve seats, with a low energy material, such as a noble metal, a perfluorinated polymer, a self-assembled monolayer, hard diamond, diamond-like carbon or a metal oxide. In other embodiments, the valves are provided with ridges and the diaphragm is adhered to the fluidic or actuation layer with an adhesive material.
US08388906B2	Apparatus for dispensing test strips A container for a diagnostic testing system consists essentially of a media dispenser embedded in the container and configured to house a plurality of test media; a first positioning device arranged on or near a first surface of the media dispenser and configured to push the plurality of test media toward a second surface of the media dispenser; and a meter for performing a diagnostic test on a sample applied to one of the plurality of test media, the meter including a closure portion configured to close the container.
US08388903B2	Supported ionic liquid reactor A chemical reactor, comprising: a) an ionic liquid, supported on a porous solid; and b) a Brønsted acid; wherein the ionic liquid serves as an adsorbent and promoter for the Brønsted acid, and the Brønsted acid is a catalyst for alkylation, oligomerization, or a combination thereof of a hydrocarbon mixture comprising at least one alkylatable hydrocarbon and at least one alkylating agent in the chemical reactor. Also, a chemical reactor, comprising: a) a gaseous HCl, which is a catalyst for oligomerization of olefins; b) a chloroaluminate ionic liquid, supported on a porous solid, wherein the chloroaluminate ionic liquid serves as an adsorbent and promoter for the catalyst; and c) a volatile hydrocarbon, which evaporates to control a heat of reaction in the chemical reactor.
US08388901B2	Non-contact radiant heating and temperature sensing device for a chemical reaction chamber An apparatus and methods are provided for heating and sensing the temperature of a chemical reaction chamber without direct physical contact between a heating device and the reaction chamber, or between a temperature sensor and the reaction chamber. A plurality of chemical reaction chambers can simultaneously or sequentially be heated independently and monitored separately.
US08388900B2	Apparatus and method for treating impurities in air and materials An assembly and method for treating or otherwise improving an atmosphere contained within an enclosed space. The enclosed space can be a container such as a bag or other housing for equipment, food and/or suitable material. Ozone is generated within an atmosphere that is exposed to the material. The generated ozone is mixed with the atmosphere. At least a portion of the generated ozone is then removed from the mixed atmosphere. The assembly and method can be used to treat contaminated sports equipment and the like, as well as to treat food storage atmospheres, such as those exposed to fresh fruits and vegetables.
US08388899B2	Exhaust gas purifying apparatus and method for manufacturing exhaust gas purifying apparatus An exhaust gas purifying apparatus includes an exhaust gas treating body, a metal casing, and a holding sealing material. The exhaust gas treating body has a longitudinal direction and includes cell walls extending along the longitudinal direction to define cells between the cells. The metal casing has an inner surface and houses the exhaust gas treating body to face the inner surface. The holding sealing material is provided between the exhaust gas treating body and the inner surface of the metal casing to hold the exhaust gas treating body in the metal casing. The holding sealing material includes an inorganic fiber aggregated body. The metal casing has a corrosion area at least on a part of the inner surface. The corrosion area includes a corroded base material of the metal casing.
US08388896B2	Exhaust gas retreatment device Provided is an exhaust gas retreatment device for an exhaust system of an internal combustion engine including a housing, in which an exhaust gas retreatment element and upstream thereof a silencer device are arranged, an inlet gas path leading from one housing inlet to an outlet of the exhaust gas retreatment element located in the interior of the housing, with an exhaust gas path following the inlet gas path which in the interior of the housing leads to the silencer device and/or through the silencer device as well as to a housing outlet. A cost-effective design can be achieved if the inlet gas path has a higher gas tightness than the exhaust gas path and/or if components of the exhaust gas retreatment device limiting the inlet gas path have a higher material quality than components of the exhaust gas retreatment device only limiting the exhaust gas path.
US08388890B2	Composition and method for applying an alloy having improved stress relaxation resistance A nickel based alloy coating and a method for applying the nickel based alloy as a coating to a substrate. The nickel based alloy comprises about 0.1-15% rhenium, about 5-55% of an element selected from the group consisting of cobalt, iron and combinations thereof, sulfur included as a microalloying addition in amounts from about 100 parts per million (ppm) to about 300 ppm, the balance nickel and incidental impurities. The nickel-based alloy of the present invention is applied to a substrate, usually an electromechanical device such as a MEMS, by well-known plating techniques. However, the plating bath must include sufficient sulfur to result in deposition of 100-300 ppm sulfur as a microalloyed element. The coated substrate is heat treated to develop a two phase microstructure in the coating. The microalloyed sulfur-containing nickel-based alloy of the present invention includes a second phase of sulfide precipitates across the grain (intragranular) that improves the stress-relaxation resistance of the alloy.
US08388887B2	Methods for making textured ceramic implants A ceramic implant having a rough surface texture and a method for forming the same. The method includes forming a green body of a first ceramic composition. The green body is reduced to smaller pieces thereby forming ceramic fragments. A mold is filled with a second ceramic composition to form a ceramic base. Ceramic fragments are added to the mold and an outer layer is formed over at least a portion of the ceramic base. Pressure is applied to the mold to compress the outer layer onto the ceramic base and to form a green assembly. The green assembly is sintered to form a ceramic implant having a rough surface texture.
US08388883B2	Process for producing thermoelectric semiconductor materials and legs The use of induction furnaces for producing thermoelectric legs and components for thermoelectric modules is described, as is a process for producing thermoelectric semiconductor materials by co-melting mixtures of the particular element constituents of the thermoelectric semiconductor materials or alloys thereof in an induction furnace and pouring the melt thus obtained into the mold of a thermoelectric leg, or spraying the melt thus obtained to produce a pulverulent thermoelectric semiconductor material.
US08388882B2	Mold for forming golf ball and golf ball manufactured using the same A mold for forming a golf ball makes it possible to form minute dimples, and to improve mold release properties of the mold and wettability of the mold by a material when a urethane material is used for a cover layer. A mold according to the present invention is a mold for forming a urethane cover as an outermost layer of a golf ball, and includes: at least two split molds that are separably joined with each other, and that includes a cavity formed therein by the joining, the cavity being for forming the urethane cover; protrusions that are formed on a cavity surface of the split molds to form dimples of the golf ball; and a composite plating film that covers the cavity surface of the split molds, that comes into contact with a material of the urethane cover, and that contains a nickel-based matrix and fluororesin particles dispersed in the nickel-based matrix.
US08388878B2	Method for producing microporous sheet Provided is a method of producing a microporous sheet material of a polymeric matrix of polyolefin, with finely divided and substantially water-insoluble filler distributed throughout the matrix, and a network of interconnecting pores communicating throughout the microporous material. The method includes: (a) forming a mixture of polyolefin, filler and a processing plasticizer composition; (b) extruding the mixture to form a continuous sheet; and (c) contacting the continuous sheet with a non-flammable extraction fluid composition to extract the processing plasticizer composition from the continuous sheet. The extraction fluid has a boiling point of 75° C. or less, and is essentially free of trichloroethylene. The microporous sheet material has Tensile Strength equal to or greater than 800 kPa. A microporous sheet material also is provided.
US08388877B2	Process of making water-dispersible multicomponent fibers from sulfopolyesters Disclosed are multicomponent fibers derived from a blend of a sulfopolyester with a water non-dispersible polymer wherein the as-spun denier is less than about 6 and wherein the water dispersible sulfopolyester exhibits a melt viscosity of less than 12,000 poise measured at 240° C. at a strain rate of 1 rad/sec, and wherein the sulfopolyester comprising less than about 25 mole % of residues of at least one sulfomonomer, based on the total moles of diacid or diol residues. The multicomponent fiber is capable of being drawn at a relatively high fiber speed, particularly at least about 2000 m/min, and may be used to produce microdenier fibers. Fibrous articles may be produced from the multicomponent fibers and microdenier fibers. Also disclosed is a process for multicomponent fibers, nonwoven fabrics, and microdenier webs.
US08388875B2	Mold goods and insert molding method For a skin, a non-formed polyurethane resin layer at the surface side and a foamed polyurethane resin layer between the non-foamed polyurethane resin layer and a base member are configured to form an integral and uniform layer over and extent from an injection point to a distant point on a surface of the base member, so that an integral skin foam in which such skin layer and foamed layer are laminated can be molded, under an atmospheric pressure, in a single process, allowing for manufacture of a laminate article with a high degree of uniformity over an appreciable wide range of the article, as well as for provision of a laminate mold goods having the skin and foamed layers formed with a high uniformity along the base member, over the length in a flow direction of skin forming material.
US08388873B2	Method for recycling all waste plastics in particular mixed plastics A method for the recycling of all types of waste plastic, in particular mixed plastic (MP), in which compactate, in particular agglomerate, is ground from flakes or other plastic parts in at least one refiner stage in the presence of water, from which fine particles are removed from the ground material emerging from the refiner stage with the process water, the remaining ground material is washed and/or mechanically dehydrated and dried or the dehydrated ground material is again ground in another refiner stage in the presence of water and then dehydrated and dried, wherein the grinding of the compactate is performed in at least one refiner stage using a disk refiner (toothed disk refiner), the disks of which have engaging teeth, which are arranged separated on concentric circles, wherein there is a hole between neighboring teeth of a circle and the holes of a circle are each big enough that the particles to be ground or ground up to that point can pass through freely.
US08388872B2	Photochromic materials having extended pi-conjugated systems and compositions and articles including the same The present invention provides a photochromic material which is an indeno-fused naphthopyran of structural formulas I or II, having a pi-conjugation extending group bonded to the 11-position of the indeno-fused naphthopyran, the pi-conjugation extending group having at least one pendent halo-substituted group bonded thereto. The pi-conjugation extending group extends the pi-conjugation system of said indeno-fused naphthopyran. The 13-position of the indeno-fused naphthopyran is substantially free of spiro-substituents. The invention further provides photochromic materials of specified structure, photochromic compositions, photochromic articles and optical elements that include the photochromic material.
US08388871B2	Translucent conductive film forming coating liquid, translucent conductive film, and dispersive type electroluminescent device A translucent conductive film-forming coating liquid that can form a translucent conductive film having excellent translucency and conductivity together with organic solvent resistance includes conductive oxide acicular powder dispersed in a solvent containing a binder resin, the glass transition point (Tg) of the binder resin being 120° C. or more.
US08388869B2	Thermally conductive resin composition including a milled pitch based carbon fiber Disclosed is a thermally conductive resin composition including (A) about 40 to about 70% by weight of polyphenylene sulfide based resin; (B) about 20 to about 30% by weight thermally conductive graphite; and (C) about 10 to about 30% by weight milled pitch based carbon fiber. The resin composition can have excellent thermal conductivity by improving thermal conductivity in a plane-direction and thermal conductivity in a Z-direction and also can have commercially usable impact strength.
US08388867B2	Cation deficient materials for electrical energy storage A composition comprising: a metal oxide of a first metal ions and second metal ions; an electrically conductive material; and a binder material. The second metal ions have a higher oxidation state than the first metal ions. The presence of the second metal ion increases the number of metal cation vacancies. A method of: dissolving salts of a first metal ion and a second metal ion in water to form a solution; heating the solution to a temperature of about 80-90° C.; and adding a base to the solution to precipitate nanoparticles of a metal oxide of the first metal ion and the second metal ion.
US08388866B2	Conductive composition and conductive cross-linked product, capacitor and production method thereof, and antistatic coating material, antistatic coating, antistatic film, optical filter, and optical information recording medium A conductive composition comprises a π conjugated conductive polymer, a dopant, and a nitrogen-containing aromatic cyclic compound. A capacitor comprises an anode composed of a porous material of valve metal, a dielectric layer formed by oxidizing the surface of the anode, and a cathode provided on the dielectric layer and having a solid electrolyte layer containing a π conjugated conductive polymer, which comprises an electron donor compound containing an electron donor element provided between the dielectric layer and the cathode. Another capacitor is based on the above-described capacitor, wherein the solid electrolyte layer further comprises a dopant and a nitrogen-containing aromatic cyclic compound. An antistatic coating material comprises a π conjugated conductive polymer, a solubilizing polymer containing an anion group and/or an electron attractive group, a nitrogen-containing aromatic cyclic compound, and a solvent. An antistatic coating is formed by applying the antistatic coating material.
US08388863B2	Silicate phosphor for UV and long-wavelength excitation and preparation method thereof The present invention relates to a phosphor for UV and long-wavelength excitation and a preparation method thereof, more particularly to a phosphor for UV and long-wavelength excitation prepared from a phosphor precursor comprising strontium, barium, zinc, silica and rare-earth metal, wherein the proportion of barium and zinc is optimized to obtain a color coordinate in the range of x=0.50-0.64 and y=0.38-0.51, and a method for preparing the same by heat-treating the phosphor precursor under a mixed gas atmosphere of nitrogen and hydrogen with specific proportion. Since heat treatment is possible even at low temperature, a phosphor for UV and long-wavelength excitation having superior luminescence characteristics and thus offering superior efficiency when applied to diodes or liquid crystal displays can be obtained without having to use conventional flux materials to lower baking temperature and without using toxic substances.
US08388859B2	Wear-resistant optical layers and moulded bodies A composition comprising a blocked and/or unblocked isocyanate compound and surface-modified nanoscale solid particles that comprise on the surface thereof organic radicals which comprise groups with an active hydrogen or precursors of such groups.
US08388856B2	Electrolyte for rechargeable lithium battery including additives, and rechargeable lithium battery including the same An electrolyte for a rechargeable lithium battery including a non-aqueous organic solvent, a lithium salt, and an electrolyte additive including a compound represented by the following Chemical Formula 1, and a rechargeable lithium battery including the electrolyte for a rechargeable lithium battery. In Chemical Formula 1, Ar1 and Ar2 are the same or different and are independently aromatic organic groups, and X is a halogen.
US08388855B2	Polyamine/alkali salt blends for carbon dioxide removal from gas streams Novel solvents and methods of use for the removal of CO2 from flue gas, natural gas, hydrogen gas, synthesis gas, and other process and waste gas streams are provided. The solvent contains an alkali salt such as potassium carbonate and a polyamine such as piperazine (PZ) where the polyamine concentration is at least 1.5 equivalents/Kg H2O and the alkali salt concentration is at least 0.5 equivalents/Kg H2O. The preferred alkali salt/polyamine ratio is from approximately 1:2 to 2:1, and no additional alcohol is required for solubilizing the PZ. This chemical solvent and method of use provides efficient and effective removal of CO2 from gaseous streams and other sources.
US08388845B2	Wastewater treatment method and wastewater treatment apparatus An aspect of the present invention provides a wastewater treatment method for treating wastewater containing ammonium nitrogen, including the steps of: oxidizing the ammonium nitrogen in the wastewater to nitrite with nitrifying bacteria in a treatment tank in which the nitrifying bacteria and anaerobic ammonium-oxidizing bacteria having a half-saturation constant of 6.1 mgN/L or more with respect to nitrite coexist; and denitrifying the nitrite formed through the oxidation of the ammonium nitrogen, with the anaerobic ammonium-oxidizing bacteria in the treatment tank, while using the ammonium nitrogen contained in the wastewater as a hydrogen donor. The method employs the anaerobic ammonium-oxidizing bacteria that can maintain the denitrification activity even under a condition in which the amount of dissolved oxygen is large, consequently can easily maintain the activities of both of the nitrifying bacteria and the anaerobic ammonium-oxidizing bacteria which coexist in the same treatment tank, and can rapidly perform wastewater treatment.
US08388843B2	Integrity testable multilayered filter device The present invention relates to a device having two or more separate filtration layers that can be independently tested for integrity yet which allow for serial filtration through the two or more layers to obtain the desired characteristics such as retention. The device is made of two or more filtration areas, each containing one filter layer. Each area has one filtration layer and a first endcap bonded to a first end of the filter and a second endcap bonded to a second end of the filter. The areas are arranged concentrically around each other such that the first area is inward of the second area which is inward of a third area and the like. Each area is formed separately and integrity tested separately before final assembly. The first area is slid into the inside of the second area and then the two endcaps are either bonded to each, bonded to a third overall endcap or overmolded by a third endcap.
US08388840B2	System for stiffening the plates of a large-diameter multi-stage column Device for stiffening the plates of a multi-stage column with a diameter of more than 2 meters, whereby each plate supports a particle bed and the flow of at least one fluid passes through it from top to bottom, whereby said device consists of a number of beams that are located under the plate in question, each beam having a lower surface that is shaped like a triangle.
US08388839B1	Oil skimming apparatus An apparatus and method for skimming oil and other liquid hydrocarbons and contaminates floating at the surface of a body of water or other suspending liquid. A rigid skimming surface such as a drum or disc is floatably supported on pontoons. The skimming surface is rotatable about an axis substantially parallel to the water surface. The skimming surface is covered with removably attached sorbent material which improves the efficiency of the oil recovery operation and which, when worn or soggy, can be removed and discarded without discarding the skimming surface.
US08388836B1	Waste separator apparatus and system for treating animal waste and the like A waste separator apparatus is provided. The apparatus includes a first screen assembly for screening fluids from a waste stream where the first screen assembly defining an enclosure. A second screen assembly is provided for screening fluids from the waste stream and is disposed closely spaced-apart within the enclosure of the first screen assembly. A waste stream pathway is defined between the first screen assembly and the second screen assembly. A first separated fluids stream pathway is defined outwardly of the first screen assembly. A second separated fluids stream pathway is defined inwardly of the second screen assembly. One or more blades extends inwardly from the first screen assembly or outwardly from the second screen assembly for advancing the waste stream through the waste stream pathway. A related system is also provided.
US08388835B2	Removably engageable storm drain inlet screen A storm drain inlet filter for preventing passage of particulate and solids in storm water entering a storm drainage system through an entry aperture. The device features a filter element held in place by a ring compressed against the sidewalls forming the entry aperture. Filter fabric may be included between two sidewalls of the inlet filter.
US08388834B2	Fuel filter The invention relates to a fuel filter (1) with a device for separating water from the fuel. This device comprises at least one filter screen element (6) placed in a filter housing (2) which is located downstream a filter element (3) for the filtration of particles from the fuel, a tank (15) located under the filter screen element (6) at the filter housing (2) in which the separated water droplets are collected, and a device for deviating the fuel between the filter element (3) and the filter screen element (6).
US08388833B2	System and process for removing nitrogen compounds and odors from wastewater and wastewater treatment system A wastewater treatment system includes independent wastewater treatment facilities. Each of the facilities has a number of wastewater treatment subsystems. A wastewater collection subsystem holds wastewater to be treated. A pump subsystem moves wastewater from a wastewater collector to a filtration subsystem having a bioreacting filter. The filter has a sump and a fluidized-bed filter therein and supports the filter upright. The filter has an upwardly expanding, hollow, conical filter body with filter media. A monitoring subsystem measures wastewater process parameters. Control devices receive control commands and, dependent upon the command received, alter parameters of the wastewater treatment subsystems. A communication device connects the wastewater treatment subsystems and the control devices and sends information corresponding to the wastewater process parameters measured by the monitors, receives control messages corresponding to the control commands, and transmits control commands the control devices to, thereby, alter a wastewater process parameter.
US08388831B2	Compact slurry preparation system for oil sand Staged crushing combined with water addition and mixing is practiced at the mine site to prepare an oil sand slurry ready for hydrotransport. More particularly, as-mined oil sand is crushed to conveyable size (e.g. −24″) using a mobile crusher. The pre-crushed ore product is conveyed to a dry ore surge bin. Ore is withdrawn from the bin and elevated to the upper end of a slurry preparation tower having downwardly aligned process components to enable gravity feed. The ore is further crushed in stages to pumpable size (e.g. −4″) by a stack of crushers and water is added during comminution. The ore and water are mixed in a mixing box and delivered to a pump box. The surge bin and tower are relocatable. Screening and oversize reject treatment have been eliminated to achieve compactness and enable relocatability.
US08388829B2	Deoxygenation of fatty acids for preparation of hydrocarbons Embodiments of methods for making renewable diesel by deoxygenating (decarboxylating/decarbonylating/dehydrating) fatty acids to produce hydrocarbons are disclosed. Fatty acids are exposed to a catalyst selected from a) Pt and MO3 on ZrO2 (M is W, Mo, or a combination thereof), or b) Pt/Ge or Pt/Sn on carbon, and the catalyst decarboxylates at least 10% of the fatty acids. In particular embodiments, the catalyst consists essentially of 0.7 wt % Pt and 12 wt % WO3, relative to a mass of catalyst, or the catalyst consists essentially of a) 5 wt % Pt and b) 0.5 wt % Ge or 0.5 wt % Sn, relative to a mass of catalyst. Deoxygenation is performed without added hydrogen and at less than 100 psi. Disclosed embodiments of the catalysts deoxygenate at least 10% of fatty acids in a fatty acid feed, and remain capable of deoxygenating fatty acids for at least 200 minutes to more than 350 hours.
US08388828B2	Recovery and use of conjunct polymers from ionic liquid catalysts A process comprising regenerating a used ionic liquid catalyst, recovering conjunct polymer from the regenerated catalyst and using at least a portion of the conjunct polymer is disclosed.
US08388827B2	Methods of using an electrochemical biosensor According to one embodiment of the present invention, an electrochemical sensor (10) for detecting the concentration of analyte in a fluid test sample is disclosed. The sensor (10) includes a counter electrode having a high-resistance portion for use in detecting whether a predetermined amount of sample has been received by the test sensor.
US08388826B2	Conversion coating for magnesium, beryllium, and their alloys and articles thereof I provide a non-toxic protein and protein compound conversion coated metal article, a painted or plated non-toxic protein and protein compound conversion coated metal article, the aqueous coating solution to provide the in-situ conversion protective coating, and a process of preparing the article. The article is a metal selected from the group consisting of magnesium, magnesium alloy, beryllium and beryllium alloy. The solution has a pH of 3.0 to 12.0 and preferably 4.0 to 10.0 and a protein and protein compound concentration of 0.1 to 10% by weight and the protein and protein compound have a molecular mass of 16,700 to 1,000,000.
US08388814B2	Method and apparatus for the treatment of dispersed material In a method for treatment of a dispersed material in a plasma, in which a plasma-forming gas is introduced into a reaction chamber and ionized and a dispersed material is introduced into the reaction chamber and into the area of the plasma, treated under the action of the plasma, and subsequently removed from the area of the plasma, the introduction of the plasma-forming gas and the introduction of the dispersed material are performed independently of one another and from different directions. In an apparatus for treatment of a dispersed material in a plasma, which comprises a reaction chamber having a plasma generator, a first inlet for a plasma-forming gas, and a second inlet for the dispersed material, the second inlet is situated spatially separated in relation to the first inlet so that the dispersed material is conducted from the outside into the plasma.
US08388810B2	Method and apparatus for producing product from stock pulp sheet A method of production of a product from a stock pulp sheet uses conveyor rolls to convey a stock pulp sheet to a crusher. During conveyance to the crusher, a defective part in the stock pulp sheet is detected by a detector. The detected defective part is removed from the stock pulp sheet by a remover. The stock pulp sheet from which the defective part is removed is supplied to the crusher to produce crushed pulp. The produced crushed pulp is used to produce a product in a product producer.
US08388799B2	Composition for forming polishing layer of chemical mechanical polishing pad, chemical mechanical polishing pad and chemical mechanical polishing method A composition for forming a chemical mechanical polishing pad having polishing characteristics such as a high polishing rate, an excellent planarity of the polished object, and less scratches of the polished object. The composition includes (A) a polyurethane having a carbon-carbon double bond on a side chain and (B) a cross-linking agent. The polyurethane (A) is preferably a thermoplastic polyurethane (A′) obtained by mixing at least components (a11) to (a13) and component (a2) in a proportion satisfying the following conditions (1) and (2) and reacting them.
US08388797B2	Process for bonding reactive adhesives to substrates The invention is a system, or kit, comprising i) a stable solution or dispersion of a catalyst for the curing of a reactive adhesive system; and in a separate part ii) an uncured reactive adhesive system wherein the catalyst of part i) accelerates the cure of the reactive adhesive system. The reactive adhesive system can be a one or two-part system. In another embodiment, the invention is a method of bonding a reactive adhesive to a substrate comprising: a) contacting a catalyst for the curing of the reactive adhesive in a volatile solvent with the surface of the substrate to which the adhesive will be bonded; b) allowing the volatile solvent to volatilize away; c) contacting a reactive adhesive with the surface treated in step a) and d) allowing the adhesive to cure. This process is performed in the absence of a primer and a film forming agent.
US08388794B2	Process for producing adhesive patch The invention provides a process for producing an adhesive patch, which includes a step of preparing a pressure-sensitive adhesive sheet including a backing, a pressure-sensitive adhesive layer formed on at least one side of the backing, and a release liner disposed on the pressure-sensitive adhesive layer; and a step of punching an adhesive patch including a backing, a pressure-sensitive adhesive layer formed on at least one side of the backing, and a release liner disposed on the pressure-sensitive adhesive layer out of the pressure-sensitive adhesive sheet with a protrudent push cutter blade, in which, at at least an edge part of the protrudent push cutter blade, a cross-sectional shape of the protrudent push cutter blade, which is in a direction perpendicular to the direction in which the protrudent push cutter blade extends, has an angle a and an angle b, in which the angle a is larger than the angle b. The angle a and angle b in the sectional shape have the meanings described in the specification.
US08388793B1	Method for fabricating camera module The invention provides a method for fabricating a camera module. An exemplary embodiment of the method for fabricating a camera module comprises providing plurality of lens sets. A dry film layer is formed on the plurality of lens sets. The dry film layer is patterned to form a plurality of dry film patterns respectively attaching to a plurality of lens sets. The plurality of lens sets are separated. A lens set separated from the plurality of lens sets is bonded to an image sensor device chip. The dry film pattern on the lens set is removed.
US08388791B2	Method for molding tensile strand elements Articles of footwear and a variety of other products may incorporate tensile strand elements. In manufacturing an element, such as the tensile strand elements, a strand, a first layer, and a second layer may be located between a first surface and a second surface of a press. The first surface includes a first material and the second surface includes a second material, with the first material having greater hardness than the second material. The strand, the first layer, and the second layer are then compressed between the first surface and the second surface.
US08388790B2	Multilayered body comprising an electroconductive polymer layer and method for the production thereof There is described a process for the production of a multilayer body (4) having an electrically conductive layer (421) arranged on a carrier layer (41), in which there is provided a transfer film (5) having a transfer layer (52) of an electrically conductive polymer. The electrically conductive layer is transferred from the transfer film (5) on to the multilayer body (4). There are also provided a transfer film and a multilayer body produced in accordance with the process.
US08388778B2	Print head with reduced bonding stress and method A method for reducing stress between a silicon chip and a bonded mounting structure having a coefficient of thermal expansion substantially different from a coefficient of thermal expansion of the silicon chip includes the step of bonding a thermal stress-attenuating layer between the silicon chip and the mounting structure. The thermal stress-attenuating layer has a coefficient of thermal expansion that is substantially similar to the coefficient of thermal expansion of the silicon chip.
US08388776B2	Method for the β annealing of a work piece produced from a Ti alloy A description is given of a method for the heat treatment of a workpiece produced from a titanium alloy for obtaining a fine-grained microstructure by annealing the same above its β-transus temperature Tβ. According to the invention, the workpiece is heated in a furnace to a temperature level TH above its β-transus temperature Tβ. Reaching the temperature level TH determines the beginning of a predefined holding time, for which the workpiece is kept at this temperature level TH. The workpiece subsequently undergoes a cooling process. To carry out the heat treatment, the furnace temperature TF is set such that, for heating up the workpiece to the temperature level intended for carrying out the holding, it lies above the temperature level TH of the workpiece determining the beginning of the holding time.
US08388772B2	Press roller annular casing and method A method for the production of an annular casing for the press rollers of roller presses for the pressure comminution of particulate material, the outer surface of which casing always has a high degree of hardness and consequently a high wear-resisting capability, but the radially inner region of which casing has a lower degree of hardness to avoid casing ruptures. The annular casing is cast of nodular cast iron with at least the alloying elements Ni and Mo. The cast body is given a bainitic structure with residual austenite by a subsequent heat treatment followed by controlled cooling. The outer surface is constantly re-hardened during use via pressure loading such that martensite is constantly formed in boundary layers of the outer surface.
US08388767B2	Carbonitriding low manganese medium carbon steel A method for processing a low manganese steel is more cost effective and improves residual stress, bending fatigue, and surface characteristics for driveline components. The low manganese steel comprises in combination, by weight, about 0.30-0.75% carbon (C) and 0.15-0.40% manganese (Mn), with the balance being essentially iron (Fe). The method for processing the low manganese steel includes carbonitriding the low manganese steel at temperatures between 1600° F. to 1750° F. for a time period of about three to six hours. The low manganese steel is subsequently quenched in a water based solution that is kept at room temperature. The process provides the low manganese steel with an irregular case profile with a core hardness of no more than 50 Rockwell C and a surface hardness of approximately 58-63 Rockwell C. Further, the process provides the low manganese steel with little or no intergranular oxidation or surface high temperature transformation product.
US08388758B2	Apparatus and method for the rapid thermal control of a work piece in liquid or supercritical fluid A surface cleaning apparatus comprising a chamber, and a thermal transfer device. The chamber is capable of holding a semiconductor structure therein. The thermal transfer device is connected to the chamber. The thermal transfer device has a surface disposed inside the chamber for contacting the semiconducting structure and controlling a temperature of the semiconductor structure in contact with the surface. The thermal transfer device has a thermal control module connected to the surface for heating and cooling the surface to thermally cycle the surface. The thermal control module effects a substantially immediate thermal response of the surface when thermally recycling the surface.
US08388756B2	Evaporation source and vapor deposition apparatus using the same An evaporation source that causes the evaporation bars to vaporize and emit small particles. The small particles of the evaporation bars are evenly dispersed all around the evaporation source. Thus, the particles then accumulate on workpieces to form symmetrical films. A vapor deposition apparatus using the present evaporation source is also described.
US08388751B2	Controlling transport of gas borne contaminants across a ribbon surface A method of growing a ribbon crystal provides a crucible containing molten material and passes string through the molten material to grow the ribbon crystal. The method further directs gas flow around the ribbon crystal such that the gas flows down along the ribbon crystal toward the crucible.
US08388750B2	Granulated kaolin compositions and processes for their production Disclosed herein are granulated kaolin compositions exhibiting at least one of improved material handling properties, low dusting during transit, easy make-down into mineral-water slurries, and requiring less energy to produce than spray dried kaolin products. The granulated kaolin compositions may, in one embodiment, be characterized by a moisture content ranging from about 12% to about 23% by weight relative to the total weight of the composition. In another embodiment, the granulated kaolin compositions may have an average granule size of greater than about 10 mesh. Also disclosed herein are granulated kaolin compositions having a moisture content ranging from about 12% to about 23% by weight relative to the total weight of the composition, wherein the composition is friable when subjected to a shear force. Further disclosed herein is a method for producing granulated kaolin compositions comprising mixing at least one kaolin slurry with at least one predispersed spray dried kaolin and agglomerating the resulting mixture. Still further disclosed herein is a system for producing granulated kaolin compositions comprising a first zone for mixing at least one kaolin slurry with at least one predispersed spray dried kaolin and a second zone for agglomerating the resulting mixture.
US08388749B2	Strontium carbonate micropowder and process for production A fine strontium carbonate powder having a BET specific surface area of 20 to 150 m2/g, which comprises spherical particles having a mean aspect ratio of 2.0 or less shows high dispersibility in liquid media and is of value for producing dielectric ceramic materials such as strontium titanate.
US08388745B1	Replaceable sieve bed for portable oxygen concentrator A sieve module includes an impermeable housing and an adsorptive media bed. The impermeable housing is puncturable at a first puncture location to receive gas from an exterior of the impermeable housing. The impermeable housing is also puncturable at a second puncture location to expel gas to the exterior of the impermeable housing. The adsorptive media bed is disposed within the impermeable housing. The gas flows through the impermeable housing from the first puncture wound to the second puncture location by flowing through the adsorptive media bed.
US08388743B2	Separation membrane module and fuel vapor processing apparatus incorporating the same One aspect of the present teachings includes a separation membrane arranged in a hollow case. A particular component concentration chamber and a particular component dilution chamber are arranged in series in the hollow case. The particular component concentration chamber is capable of increasing concentration of the particular component by allowing permeation of the particular gas through the separation membrane. The particular component dilution chamber is capable of increasing concentration of the particular component by not allowing permeation of the particular gas through the separation membrane. The particular component concentration chamber and the particular component dilution chamber are configured such that only a gas containing the particular component and permeated through the separation membrane or only a gas containing the particular component not permeated through the separation membrane in one of the chambers disposed on an upstream side (i.e., the side of the inlet port) can flow into the other of the chambers.
US08388739B2	Method for treating contaminated gas A method for treating natural gas using a vessel having a manifold for introducing gas in the vessel, a flow disperser above the manifold that prevents channeling of the gas, a spray system for spraying a treating liquid into an upwardly rising column of gas and, optionally, a liquid level controller for maintaining the level of a pool of treating liquid above the flow disperser.
US08388738B2	Method for removing carbon dioxide from fluid flows, in particular combustion exhaust gases A process for removing carbon dioxide from a fluid flow, wherein a) the fluid flow is brought into contact with an absorption agent which contains a solution of ammonia and at least one amino carboxylic acid and/or amino sulfonic acid, a charged absorption agent being obtained, and b) the charged absorption agent is regenerated while releasing carbon dioxide. The additional use of the amino carboxylic acid and/or amino sulfonic acid increases the circulation absorption capacity of the absorption agent.
US08388732B2	Integrated membrane and adsorption system for carbon dioxide removal from natural gas The present invention relates to an integrated membrane/adsorbent process and system for removal of carbon dioxide from natural gas on a ship that houses natural gas purification equipment. Additional membrane units or adsorbent beds are used to reduce the amount of product gas that is lost in gas streams that are used to regenerate the adsorbent beds. These systems produce a product stream that meets the specifications of less than 50 parts per million carbon dioxide in natural gas for liquefaction.
US08388731B2	Modular ductwork decontamination assembly A modular ductwork assembly decontaminates an air stream circulating within a heating, ventilation and air conditioning (HVAC) system. The assembly includes one or more of (a) an ionizing module for removing particulates from the air stream, (b) a sterilization module for neutralizing airborne pathogens present in the air stream, (c) an ozone treatment module for neutralizing pathogens or odoriferous constituents or volatile organic compounds (VOCs) present in the air stream, optionally (d) baffles for slowing and disrupting the flow rate and promoting turbulence in the air stream traveling through the modules and optionally (e) a fan module for directing a treated air stream, (f) an ozone sensor, (g) a monitoring or ozone control means, (h) a means of delivering and repurposing generated ozone. Each of the modules is arranged substantially adjacent to at least one of the other modules.
US08388728B2	Leaching ores A process for leaching an ore containing sulfidic copper-containing minerals includes carrying out an aerated oxidizing leach of a part of the ore and producing an acidic leach liquor containing ferrous ions, ferric ions, and copper ions in solution. The process also includes carrying out a leach of another part of the ore using the leach liquor under conditions that minimize reactions with a source of iron in the ore and producing a leach liquor containing copper ions in solution. The process further includes recovering copper from the leach liquor.
US08388727B2	Continuous and semi-continuous process of manufacturing titanium hydride using titanium chlorides of different valency The invention relates to the manufacture of titanium hydride powder using continuous or semi-continuous process, and using titanium slag or synthetic rutile as raw materials, while hydrogen, titanium tetrachloride, titanium trichloride, titanium dichloride, and hydrogen chloride are participate as intermediate reaction products. The continuous comprises: (a) reduction of TiCl4 to low titanium chlorides followed by cooling a mixture, (b) separating of residual TiCl4 from solid low chlorides by heating the mixture in argon or vacuum up to 150° C. followed by removing the titanium tetrachloride from the mixture, (c) dissociation of TiCl3 to TiCl2 at 450° C. in vacuum followed by removal of gaseous titanium tetrachloride from the reaction zone, condensation to the liquid, and returning back into the reaction retort, (d) dissociation of TiCl2 in vacuum at 750-850° C. to manufacture fine powder of metallic titanium and titanium tetrachloride, whereby hydrogen heated up to 1000° C. is used to accelerate this reaction, and (e) saturation of the fine titanium powder by hydrogen at 400-640° C. to manufacture final product of titanium hydride powder which is free of oxygen or nitrogen. The semi-continuous process includes the Kroll's process as the very first step.
US08388724B2	Solder paste High-temperature solders having a higher melting point than solder alloys used for soldering of printed circuit boards are used for internal bonding of electronic parts, but high-temperature solders which are free from Pb have not been developed. There exist high-temperature solders which comprises Sn balls and Cu balls and which perform bonding through the formation of an intermetallic compound without melting to form a single-phase structure, but they have poor wettability to the lands of a printed circuit board or electrodes of electronic parts and have not been used.A solder paste according to the present invention is provided by mixing flux with a powder mixture of Sn powder or an Sn based lead-free solder powder with Cu or Ag powder which has Ni plating formed on its surface. Although the solder paste performs bonding by means of an intermetallic compound without melting to form a single phase structure, the Ni plating acts as a barrier which retards the formation of the intermetallic compound so as to leave enough time to permit wetting of the lands of a printed circuit board or electrodes of an electronic part.
US08388717B2	Furnace filter adapters and braces An adapter is provided for placement within a furnace filter bay having a flow of air therethrough. The filter bay is for receiving a furnace filter. The adapter includes a filter abutment face for abutment with at least a portion of the furnace filter, a mounting face parallel to the flow of air and attachment means permitting removable attachment of the adapter to the furnace filter bay. The adapter allows filters of smaller depth than the filters originally designed for use within the filter bay to be used, thereby eliminating the need for purchasing the original filters. A brace is also provided for the same purpose. A kit is described that includes the adapter and/or brace, along with instructions for installation thereof within the filter bay.
US08388714B2	Bag filtration system for a forced air furnace A bag filtration element and system for its installation in a forced air furnace where the filtration element includes a channel element frame that receives rectangular bag frames fitted thereto that each received an open bag neck end fitted thereto, and the rectangular bag frames are fitted side by side into the channel element frame, whose upper end closes the frame into a rectangle, and, the bag ends are folded around the bag frames sides and connected. A rectangular opening is formed into the plenum of a furnace inlet air duct to extend, at an upward angle, across the rectangular opening, between opposing inner walls of the air duct, and a door is provides for positioning over the duct rectangular opening with the bag filtration element installed therein.
US08388712B2	Particulate matter retaining and purging system Systems and methods are provided for operating a particulate matter retaining system having at least a first and a second filter, coupled to an engine intake. One example method comprises, during a first condition, operating in a first mode with the first filter storing particulate matter and the second filter releasing stored particulate matter. The method further comprises, operating in a second mode with the first filter releasing stored particulate matter and the second filter storing particulate matter, the exhaust gas flowing in an opposite direction as compared to the first mode. The method further comprises, operating in a third mode with both the first and the second filter storing particulate matter. During the modes, at least some tailpipe gas is drawn from between the first and second filters for expulsion to the atmosphere.
US08388709B2	Coated article A coated article, in particular a tool for cutting machining, has at least one titanium diboride layer which has been deposited by a thermal CVD process and has a thickness of at least 0.1 μm. The titanium diboride layer has an extremely fine-grained microstructure with an average grain size of not more than 50 nm.
US08388707B2	Steam methane reformer and hydrogen station having it using high performing metal fiber burner The steam methane reformer using a premixed metal fiber burner which has a short flame length as well as a high temperature to thereby provide a high efficiency and also reduce a size, and a hydrogen station having the same. The steam methane reformer using a high performing metal fiber burner comprises a reforming part (110a) in which a catalyst for steam-reforming hydrocarbon materials and producing hydrogen is disposed; a combustion part (120) which is provided with a premixed metal fiber burner (120a) for generating heat required for the steam reforming reaction of the reaction tubes (110a); a raw material supplying part (130) for supplying hydrocarbon materials to the reaction tube (110a); and a hydrogen discharging part (140) for discharging hydrogen produced through the steam reforming reaction by the catalyst of the reaction tube (110a).
US08388698B2	Emulsion dyeing composition containing at least one polyamine, at least one nonionic surfactant and at least one carboxylic acid, and method of using same The present invention is drawn to a composition and method for dyeing keratinous substrates containing: (a) at least one polyamine compound comprising at least three amino groups; (b) at least one nonionic surfactant; (c) at least one compound chosen from an alkyl ether carboxylic acid, an alkyl ether carboxylate, a fatty acid having from about 6 to about 40 carbon atoms, and mixtures thereof; (d) at least one dye chosen from oxidation dye precursors and direct dyes. The compositions of the present invention may optionally contain at least one thickening agent, at least one alkaline agent, at least one fatty substance, at least one salt, and at least one oxidizing agent.
US08388697B2	Emulsion dyeing composition containing at least one amine, at least one nonionic surfactant and at least one phosphate ester, and method of using same The present invention is drawn to a composition and method for dyeing keratinous substrates containing: (a) at least one fatty monoamine compound; (b) at least one nonionic surfactant; (c) at least one phosphate ester chosen from alkoxylated alkyl phosphate esters and alkyl phosphate esters; (d) at least one dye chosen from oxidation dye precursors and direct dyes. The compositions of the present invention may optionally contain at least one thickening agent, at least one alkaline agent, at least one fatty substance other than a fatty acid, at least one salt, and at least one oxidizing agent.
US08388694B2	Handling device for persons with a limited gripping function and also wheelchair comprising a device of this type A handling device for persons with a limited gripping function, in particular for gripping utensils such as pens, comprising an orthotic support adapted to be secured to a part of the body of the person; a utensil holder situated on the support, wherein the utensil holder includes gripping means; and a pneumatic, electric, or magnetic drive system or a combination thereof operative on the gripping means. Also described is a wheelchair, comprising the aforementioned handling device, thus allowing optimum carrying and operation or use of the device.
US08388691B2	Drainage devices A ureteral drainage stent is designed to be placed in a patient's ureter and extend into a patient's bladder. An ureteral drainage stent includes a distal region for placement in the ureter and renal cavity, and a proximal region for placement in a urinary bladder and urethra. The distal region includes an elongated member with multiple lumens and the proximal region includes multiple elongated member, each defining a lumen. At least one lumen in the distal region is in liquid communication with a lumen from the proximal region. At least two of the elongated members in the proximal region are joined at their proximal ends and form a retraction structure, a structure used for removing the stent from a patient.
US08388690B2	Osteotomy system An osteotomy system, typically for tibial alignment correction, includes a wedge implant and an osteotomy guide. The wedge implant is generally U-shaped and its upper and lower surfaces may be inclined with respect to one another in two orthogonal planes to correct respective misalignments. The osteotomy guide controls cutting of the osteotomy opening and the drilling of a hole defining the apex of the osteotomy, forming a bony hinge about which the osteotomy may be opened.
US08388689B2	Alignable prostheses system and method A prosthesis is provided for replacing a portion of a bone making up a joint. The prosthesis is adapted, intraoperatively, to optimize the anatomical alignment of the prosthesis in the joint. In particular, a jig is used to identify the axis of rotation of the joint intraoperatively and to align a portion of the prosthesis with the identified axis. The angle of the head of the prosthesis is adjusted to optimize contact with the appropriate corresponding portions of the joint, at which point the position of the head is fixed to prevent further rotation of the head relative to the remainder of the prosthesis.
US08388686B2	Intervertebral implant with tiltable joint parts An intervertebral implant (1) including an upper section (10) provided with a ventral side area (11), a dorsal side area (12), two lateral side areas (13, 14), a top apposition surface (15) and a bottom surface (16), a lower section (20) provided with a ventral side area (21), a dorsal side area (22), two lateral side areas (23,24), a bottom apposition surface (25) and a top surface (26). The two sections (10,20) are moveable in relation to each other by means of two joints (38;39) arranged between the two sections (10;20), wherein each of the joints (38;39) has a swivel axis (3;4) and the two swivel axes (3;4) are arranged perpendicular to each other, and each joint (38;39) comprises a first joint section (31;32;33) with an elevation (49;50) provided with an edge (51;53) for the bearing of a second joint section (31;32;33) in a way that allows titling around the swivel axis (3;4).
US08388685B2	Artificial intervertebral disc The present invention is directed to the field of prosthetic devices. More particularly, one embodiment of the present invention is directed to an artificial disc that can be used as a replacement for an intervertebral disc (e.g., a human intervertebral lumbar disc, a human intervertebral cervical disc and/or a human intervertebral thoracic disc).
US08388684B2	Artificial disc device An artificial disc device for replacing a damaged nucleus is disclosed. In one form, the device may be inserted in components such that the device may be assembled within and retained by the natural annulus therein. In another form, the device may be inserted into the natural annulus in a collapsed or compressed state or arrangement and then be expanded within and retained by the annulus therein.
US08388683B2	Method and assembly of a pyrolytic carbon component attached to another component A prosthetic assembly and a method of assembling same. The prosthetic assembly includes a base component with at least one engagement surface. A pyrolytic carbon component includes at least one engagement surface. The pyrolytic carbon component is elastically deformed to mechanically interlock with the engagement surface on the base component. The pyrolytic carbon component retains at least a portion of the deformation stress created during coupling with the base component.
US08388682B2	Bronchial flow control devices and methods of use Disclosed is an assembly for loading a bronchial flow control device into a container, such as into a delivery catheter. The assembly includes a funnel housing and a puller housing that mate with one another. The funnel housing defines a funnel-shaped loading cavity that receives a flow control device and that gradually reduces in size moving in a first direction. The puller housing is removably attached to the funnel housing and is also removably attachable to a bronchial flow control device that can be positioned in the loading cavity. The puller housing pulls the bronchial flow control device in the first direction through the funnel housing to gradually contract the bronchial flow control device into a compressed state of reduced size relative to the expanded size.
US08388681B2	Intraocular lenses having a visible light-selective-transmissive-region Intraocular lenses are provided having a visible-light selective transmissive zone defined therein. The visible light-selective transmissive zone can be located near the lens center and designed to reduce the transmission of any wave-length of visible light specifically light in the blue light region having wavelength between approximately 400λ to 550λ. In one embodiment he IOLs are made from acrylates and the light absorbing compound is a yellow dye.
US08388680B2	Methods and devices for catheter advancement and delivery of substances therethrough Methods and devices for successively advancing a plurality of catheters over a guide element to a body tissue are described. In some of the methods, the guide element may be attached to the body tissue, which may be accessible minimally invasively. In certain variations, the guide element may not be detached from the body tissue after the catheters have been advanced over the guide element. The methods may further comprise deploying at least one implant from at least one of the plurality of catheters. In some variations, a method may comprise advancing a first delivery catheter to a first region of a body tissue, deploying a first anchor from the first delivery catheter, where the first anchor is attached to a guide element, proximally withdrawing the first delivery catheter, advancing a second delivery catheter over the guide element, and deploying a second anchor from the second delivery catheter.
US08388674B2	Conformable stents and methods for making Materials and methods for making conformable stents. The stents can be generated by, for example, injecting a fluid into a scaffold on the outer surface of an angioplasty balloon inflated at the site of a stenosis, and allowing the fluid to harden or set, thus generating a stent that can remain in the vessel at the site of stenosis.
US08388673B2	Polymeric stent A strut pattern of an endoprosthesis includes a plurality of W-shape cells that define a tubular body, the W-shaped cells at the opposite ends of the tubular body have a modified configuration that is different than the W-shaped cells at the middle portion of the tubular body. At the distal end of the tubular body, the W-shaped cells have crests with axial positions that are axially spaced apart, and have troughs with circumferential positions that are spaced apart. At the intermediate and distal end of the tubular body, the W-shaped cells crests with axial positions that coincide and have troughs with circumferential positions that coincide. The strut pattern is cut from a tubular precursor construct made of PLLA that has been radially expanded and axially extended by blow molding.
US08388671B2	Methods for treatment of aneurysmal tissue Methods and apparatus for stabilizing vascular tissue adjacent the site of the placement of an intravascular repair vehicle such as a stent graft are provided. Thus, there is provided a method for stabilizing a segment of a blood vessel for placement of an intravascular repair vehicle comprising: isolating the segment of the blood vessel; infusing the isolated segment with a sclerosing agent creating a sclerosed segment; removing the sclerosing agent; and deploying the intravascular repair vehicle at the sclerosed segment.
US08388670B1	Sensor/lead systems for use with implantable medical devices Techniques are provided for equipping sensing/pacing leads with physiological sensors without requiring additional conductors within the leads. In a bipolar lead example for use with a pacemaker, a sensor is connected between tip and ring conductors of the lead. The sensor is configured to be activated only in response to enhanced pacing pulse (EPPs) having magnitudes or durations greater than typical pacing pulses or in response to impedance detection pulses (IMPs). In a unipolar example, the sensor is connected to the tip conductor and includes an output terminal on the external housing of the lead for providing a return current path to the pacemaker. The sensor of the unipolar lead is likewise configured to respond only to EPPs or IMPs. In other examples, the sensors are configured to be fitted to the external housing of the lead and to derive power from the lead via electromagnetic induction. Still other examples include actuators rather than sensors.
US08388669B2	Hair growth modulating method and modulation device thereof A modulating light having a wavelength of 400 nm to 600 nm is irradiated to a portion around hair roots at an energy of 0.01 J/cm2 to 1 J/cm2 over a time period of not more than 1 ms as a flash light such that a light absorptive component existing in a human body around the hair roots absorbs the light for modulating hair growth without causing substantial adverse effect.
US08388666B2	Locking screw system with relatively hard spiked polyaxial bushing A polyaxial locking screw system includes a bone plate defining a plate hole with an inner spherical surface and a relatively harder split polyaxial bushing with a outer spherical surface provided within the plate hole for receiving a bone screw. In one embodiment, the plate is formed from titanium alloy, while the bushing is formed from a cobalt chrome alloy. The outer surface of the polyaxial bushing includes a plurality of spikes. When the screw is inserted into the bushing, since the bushing material is considerably harder than the plate material, the forceful expansion of the bushing during screw insertion causes the spikes to penetrate into the inner spherical surface of the hole, thereby increasing the frictional engagement of the bushing to the plate to lock the screw at a desired angle.
US08388664B2	Low profile implant locking plates An implant locking plate system and a method of using such a system are provided. The implant locking plate system generally includes at least one “T”-headed bone anchor, such as a screw or bolt that can be inserted into a vertebral body adjacent to the artificial disc to be stabilized, and a stabilizing plate attached to the bone anchor designed to overlap at least a portion of the artificial disk or graft when the bone anchor is inserted into the vertebral body adjacent to the artificial disk or graft.
US08388660B1	Devices and methods for superior fixation of orthopedic devices onto the vertebral column A bone anchor is driven into the pedicle portion of the vertebral body until a shoulder protrusion within the proximal aspect of the anchor abuts the bone surface and prevents further anchor travel into the bone. A feature within the distal aspect of the anchor is actuated producing the emergence of a distal shoulder protrusion. The latter directly abuts the distal aspect of the pedicle at the pedicle/vertebral body interface. Using this method, the anchor captures the pedicle portion of bone and contains it between the proximal and distal shoulder abutments.
US08388654B2	Method and apparatus for attaching soft tissue to bone A soft tissue repair system comprising: at least one anchor, the at least one anchor comprising a body, a bone-engaging element attached to the body for securing the body in bone, and a suture-attaching element attached to the body for attaching suture to the anchor, the suture-attaching element being configured so as to permit suture to be snared by the suture-attaching element after the anchor has been deployed in the bone.
US08388653B2	T-type suture anchoring devices and methods of using same Suture anchoring devices are disclosed, including a T-tag anchoring device that is suitably small enough to fit into the hollow tip of a needle and, furthermore, provide protection to the suture against being cut or otherwise damaged by the sharp edge of the needle tip. One disclosed device includes a slot for providing a pivot point between the suture and the body when deployed, which can be employed to form a T-tag.
US08388645B2	Intravascular filter restraining device A filtering device includes a filter that captures embolic material, a plurality of biased support struts that expand outwardly to deploy the filter, and a restraining mechanism. The restraining mechanism applies a restraining force that prevents the plurality of biased support struts from expanding outwardly to deploy the filter. An actuating member cooperates with a portion of the restraining mechanism to release the restraining force and allow the filter to deploy.
US08388644B2	Embolic protection device and method of use A medical device for embolic protection within a patient's body vessel is provided. The device includes inner and outer tubular members each having proximal and distal ends and a lumen formed through the proximal and distal ends. A flexible everting filter portion includes a body having a first end attached to the distal end of the inner tubular member and a second end attached to the distal end of the outer tubular member. The inner and outer tubular members are movable relative to one another to position the filter portion within the body vessel. The filter portion is movable from a collapsed, everted delivery and removal configuration to an expanded, generally non-everted deployed configuration. The filter portion expands radially outward to engage the filter body with the body vessel. The filter portion allows the passage of blood cells and prevents the passage of emboli or thrombi through the body vessel.
US08388634B2	Device for connecting two blood vessels A device for connecting abutting ends (1) of two blood vessels (2) that will be continuous after being mutually connected (anastomosis), the device primarily and substantially including a supporting part (3) that can be inserted in the two ends (1) of the blood vessel (2) to be connected, made, for example, of plastic or metal, particularly in the form of a mesh, grid, or cage. The supporting part (3) can be inserted into the blood vessels (1) far enough that the faces (4) of the blood vessel ends (1) can be brought into contact with each other and are in contact with each other in the usage position. The outer cross-section of the supporting part (3) in the usage position is thereby approximately the same as the inner cross-section of the blood vessel (1) in question and has an inner pass-through cross-section (lumen), so that blood can flow unhindered, but the blood vessels (1) in contact with each other are fixed at the same height to each other on the inside, and secured against sideways deflection relative to each other or sideways deflection of the blood vessel walls. The supporting part (3) can be made from one or two pieces.
US08388632B2	Tissue capturing and suturing device and method A combination tissue apposition and suture capturing device (100) for performing endoscopic procedures typically in the gastro-esophageal tract. The device (100) is particularly adapted for forming multiple plications used in a gastroplasty procedure devised to cure or ameliorate gastro-esophageal reflux disease. The device include a tissue sewing capsule (102) attached to the distal end of an endoscope having a needle (120) that is deposited in a capsule (102) distal tip cavity following the suturing of a tissue fold and retrieved to enable the suturing of a subsequent tissue fold without the need for multiple intubations. A suture clip delivery device (200) is also disclosed that is adapted to fit within the capsule to enable suture capture without the need for multiple intubations. The combination device eliminates the need for an overtube and maximizes the speed efficiency of the gastroplasty procedure. A method for using the combination device is also disclosed.
US08388628B2	Expandable sheath for delivering instruments and agents into a body lumen and methods for use Apparatus and methods are provided for delivering a guidewire, agents, and the like through an occlusion in a body vessel or other body lumen. The apparatus includes a flexible catheter or other elongate member including a proximal end, a distal end sized for insertion into a body lumen, and a first lumen extending from the proximal end to a distal region of the tubular member. An expandable sheath is provided on the distal region of the catheter that is expandable from a contracted condition to minimize a profile of the sheath to allow insertion along with the tubular member into a body lumen, to an enlarged condition wherein the sheath at least partially defines a lumen communicating with and extending distally from the first lumen of the tubular member.
US08388625B2	Support orthopaedic device for a knee joint Support orthopaedic device (1) for a knee joint, comprising a proximal connector (2) and a distal connector (3), articulated among themselves and respectively intended to be associated with a proximal bone (100) and a distal bone (101) of a lower limb connected among themselves by a knee joint. The device comprises a first rod (4a) and a second rod (4b), which are hinged, according to hinging axes normal to a median excursion plane of the orthopaedic device (1), to the proximal connector (2) and to the distal connector (3) so as to form with them an articulated quadrilateral. The articulated quadrilateral is planarly mobile according to a plane parallel to the excursion plane between a configuration corresponding to an extended position of the knee joint and configurations corresponding to bendings of different entity of the knee joint; the relative motion imposed to the proximal and distal connectors (2, 3) by the articulated quadrilateral is consistent with the physiological movement of the knee joint.
US08388624B2	Trochlear resurfacing system and method A system for repairing a defect on an articular surface of a patient's trochlear region, the system comprising a guide block comprising a body having an exterior surface configured to engage with the saddle portion and ridge portions of the patient's trochlear region, a protrusion extending generally from the body and configured to be received in a first bore formed in the articular surface along a reference axis, and a first cavity extending through the body configured to establish a first working axis displaced from the reference axis, wherein the exterior surface of the body and the protrusion are configured to secure the location of the guide block about the patient's trochlear region. A method for preparing an implant site in bone, comprising: establishing a reference axis extending from the bone; creating a bore in the bone by reaming about the reference axis; securing a guide block about the articular surface; establishing a first working axis extending from the bone using the guide block, the first working axis is displaced from the reference axis; and creating a first socket in the bone by reaming about the first working axis, wherein the first socket partially overlaps with the bore.
US08388622B2	Surgical file instrument construction with mechanism to convert rotary motion to reciprocal motion A surgical file instrument comprising a file, file guide, an outer split casing, a motion converter converting rotary motion to reciprocal motion and file assembly. The file assembly consists of an angular shaped elongated tube fairing into a generally flat portion defining the guide for the blade of the file, a complementary shaped file and a plastic rod insert having a lumen for the file and a lumen defining a passage for flowing a fluid to the surgical site. The motion converter consists of a planetary gear system connected to the battery powered motor that rotates a platen which in turn drives a cam and cam follower fitted into the cam slot for driving a drum for producing rectilinear motion. The file assembly is attached to the drum for reciprocating the file blade for use in a medical procedure for removing bone or a portion thereof.
US08388617B2	Barrel system for use with an endoscope The present embodiments provide apparatus and methods for facilitating cauterization of tissue. In one embodiment, the apparatus comprises a proximal barrel and a distal barrel, which are coupled together and moveable with respect to one another. At least a portion of the proximal barrel may be coupled to an endoscope to secure the apparatus to the endoscope. At least one electrocautery member is disposed within a lumen of the distal barrel and configured to cauterize at least a segment of tissue pulled into a lumen of the proximal barrel and/or the lumen of the distal barrel.
US08388615B2	Electrosurgical device with controllable electric field profile An electrosurgical device includes a plurality of electrodes arranged to form a tissue treatment surface and a power supply. The power supply is configured to deliver a first drive signal with a first phase to at least a first one of the plurality of electrodes and a second drive signal with a second phase to at least a second one of the plurality of electrodes such that an electric field extends from the tissue treatment surface, where the first phase and the second phase are different. The power supply is further configured to receive an input from an operator of the electrosurgical device, and adjust the first phase or the second phase such that an aspect of the electric field extending from the tissue treatment surface changes in response to the input from the operator.
US08388613B1	Methods and apparatus for microwave tissue welding for wound closure Methods and apparatus for joining biological tissue together are provided. In at least one specific embodiment, a method for joining biological tissue together can include applying a biological solder on a wound. A barrier layer can be disposed on the biological solder. An antenna can be located in proximate spatial relationship to the barrier layer. An impedance of the antenna can be matched to an impedance of the wound. Microwaves from a signal generator can be transmitted through the antenna to weld two or more biological tissue pieces of the wound together. A power of the microwaves can be adjusted by a control circuit disposed between the antenna and the signal generator. The heating profile within the tissue may be adjusted and controlled by the placement of metallic microspheres in or around the wound.
US08388612B2	Temperature monitoring return electrode An electrosurgical return electrode includes a conductive pad including a patient-contacting surface configured to conduct electrosurgical energy, and a temperature sensing circuit coupled to the conductive pad. The temperature sensing circuit includes a plurality of switching elements connected in series, wherein each of the plurality of switching elements is configured to vary in impedance in response to temperature changes, such that an interrogation signal transmitted therethrough is indicative of the temperature change.
US08388609B2	System and method for multibeam scanning System and method of photoaltering a material. The system includes a laser source operable to produce a primary pulsed beam, a holographic optical element configured to receive the primary pulsed beam and transmit a plurality of secondary beams, and a scanner operable to direct the secondary beams to the material. The secondary beams are based on the primary pulsed beam. The method includes phase shifting a pulsed laser beam to produce an input beam, holographically altering the input beam to produce a plurality of transmission beams, and scanning a portion of the material with the transmission beams.
US08388599B2	Method with balloon catheter having first and second inflatable elements The present invention relates generally to dilatation balloon catheters and systems used for expansion against an obstruction within a body vessel or channel, or to deliver devices such as, but not limited to, stents and therapeutic agents to sites within vascular or tubular channel systems of the body.
US08388598B2	Method and device for controlling several infusion pumps The invention concerns a method and device for controlling a number of infusion pumps 2-10, whereby each infusion pump (2-10) has an infusate assigned to it which is administered within a pre-determinable period of time assigned to it as an infusion at a pre-determinable infusion rate to a living being, whereby the infusion pumps (2-10) exchange control data for activating and deactivating the various infusions in a chronologically coordinated manner autonomously.
US08388595B2	Disposable undergarment with a detachable crotch member and method for the use thereof A disposable undergarment includes a body chassis member elongatable in at least a first direction between at least a first condition and second condition. The body chassis member has a greater elongation when in the second condition than when in the first condition. The disposable undergarment further includes a crotch member detachably connected to the body chassis member at at least one attachment location. At least a portion of the at least one attachment location is detached as the body chassis member is elongated between the first and second conditions. In one preferred embodiment, the crotch member includes an absorbent component. Methods of using the undergarment and of instructing a user about the use of the garment are also provided.
US08388581B2	System for treating the heart with potentially embolic agents through a right heart approach Devices and methods are described for delivery of therapeutic substances to a depth within the heart muscle via the venous side of the heart, with a primary focus on delivery through the coronary sinus. The devices and methods may be combined with percutaneous access catheters in order to provide for right heart delivery of therapeutic agents.
US08388577B2	Heating/cooling system for indwelling heat exchange catheter A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform.
US08388569B2	Delivery devices and methods with collimated gas stream and particle source Delivery devices, methods and systems are provided for the delivery of particles into a biological tissue. The device includes a gas source comprising a gas or capable of selectively producing a gas; a first particle source comprising a first plurality of particles; a first collimator fluidly connected with the gas source and adapted to form a collimated stream of the first plurality of particles entrained in the gas. The device also includes a tissue-interfacing surface adapted to interface with a surface of the tissue and orient the first collimator with the tissue such that the collimated stream of the first plurality of particles will penetrate the tissue in a direction substantially perpendicular to the surface of the tissue.
US08388567B2	Apparatus for extracorporeal blood treatment In an apparatus for extracorporeal blood treatment, an extracorporeal circuit (6) is connected to a blood chamber (3) of a membrane device (2). A pump (10) displaces a priming fluid from a source of a priming fluid (9) to a drainage (11) for discharging the priming fluid. A control unit (13) is provided with a processor which controls the pump at a preset first flow rate value, and receives from a pressure sensor (12) a first pressure value, compares the first pressure value with a reference pressure value and, on the basis of this comparison, determines whether or not the extracorporeal circuit is of a pediatric type or of an adult type. The invention is particularly useful during a stage of readying a dialysis apparatus.
US08388564B2	Hyperextension knee brace A knee brace for treating hyperextension in a patient's knee. The knee brace includes two lateral uprights and a back support positioned horizontally to and generally at a middle portion of the lateral uprights. The lateral uprights and the back support define an integral frame. A plurality of straps includes a thigh, shin and patella strap connected at opposed ends to the frame for securing the brace to the patient. A plurality of cushion pads is disposed along inner surfaces of the lateral uprights and the thigh and shin straps for providing comfort and for mitigating brace migration. An inflatable air bladder is located on an inner surface of the back support for positioning behind the knee. The air bladder has an inflation tube for increasing or decreasing the air volume within the air bladder to affect a range of motion for the patient's knee.
US08388558B2	Walking assistance device A walking assistance device has a drive mechanism, which is provided with a linear-motion actuator including an electric motor installed in the upper link member, nut members which are rotationally driven by the electric motor, and a linear-motion output shaft which linearly moves in the direction of the axial centers of the nut members, and a crank arm which is secured to the lower link member coaxially with a joint axis of a third joint and swingably attached to one end of the linear-motion output shaft. The drive mechanism is constructed such that a translational force output from the linear-motion output shaft of the linear-motion actuator is converted into a rotational driving force of the third joint through the crank arm.
US08388555B2	Posture state classification for a medical device Techniques relate to operating a medical device in response to a detected posture state of a patient. A trigger event such as a request to modify how therapy is being delivered to the patient may cause a determination to be made as to whether the patient's posture state is stable. If the posture state is stable, an association is created between the posture state and one or more therapy parameter values. Over time, a library of such associations is created that may reflect any posture state in three dimensional space, wherein a posture state comprises at least one of a posture and an activity component. The library of associations may be used to automatically control therapy delivery. Similar ones of the associations may automatically be grouped into posture state regions to facilitate more efficient classification of the patient's posture state to control therapy delivery.
US08388552B2	System for withdrawing small amounts of body fluid A system is provided for withdrawing small amounts of body fluid from an animal or human. The system includes a holder and a disposable lancing unit attached to the holder. The lancing unit also includes an open capillary channel for transporting the body fluid and piercing the skin.
US08388551B2	Method and apparatus for multi-use body fluid sampling device with sterility barrier release A device for use with a gripper is provided. A cartridge is provided that defines a plurality of cavities. A plurality of penetrating members are at least partially contained in the cavities of the cartridge. The penetrating members are slidably movable to extend outward from the cartridge to penetrate tissue. Each cavity has a longitudinal opening that provides access to an elongate portion of the penetrating member. A sterility barrier is coupled to the cartridge. The sterility barrier covers a plurality of the longitudinal openings. The sterility barrier is configured to be moved so that the elongate portion is accessed by the gripper without touching the barrier.

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