Document Document Title
US08283841B2 Motor end cap with interference fit
A rotary machine (e.g., motor or generator) has end caps with plastic piloting rings that engage a stator's plastic winding frame in an interference fit, so that a rotor seated by bearings in the end caps is properly aligned with the stator. The flexibility of the plastic-to-plastic fit allows looser tolerances in comparison to machining of all-metal end caps, while the average circle of the piloting ring's outer diameter still assures proper concentricity of rotor shaft, bearings, piloting rings and stator.
US08283835B2 Guided bulk acoustic wave device having reduced height and method for manufacturing
Guided bulk acoustic wave devices and method for manufacturing guided bulk acoustic wave devices are provided. A guided bulk acoustic wave device includes a resonator structure with a piezoelectric layer, an electrode layer for exciting guided bulk acoustic waves and a wave guide layer. The thickness of the piezoelectric layer is less than or equal to 50 μm.
US08283831B1 Brushless DC motor having multiple parallel windings
A brushless DC motor has at least three stator sections and a single rotor rotating with the three stator sections. Each stator section is wound with three parallel windings having respective three nodes. Each stator section has nine terminals providing independent access to each node so that separate voltages and currents are applied to each parallel winding in the stator section. Thus, the current applied to each stator section is divided substantially equally among the three parallel windings, thereby reducing the current in each winding for the same power requirement for the motor, which reduces the I2R losses in the windings and the supply wiring and reduces the power handling requirements in the electronic switches providing the supply voltages. The three parallel windings are connected to external terminals of the motor to form either a delta winding configuration or a wye (star) winding configuration.
US08283829B2 Axial gap motor
There is provided an axial gap motor including a rotor rotatable around a rotation axis; and a first stator and a second stator arranged to face each other with the rotor therebetween from both sides of the rotor in the rotation axis direction of the rotor, wherein the rotor includes a plurality of main permanent magnets having magnetizing directions in the rotation axis direction of the rotor and arranged in a peripheral direction of the rotor; a partition member arranged between the main permanent magnets which are adjacent to each other in the peripheral direction of the rotor, the partition member including a nonmagnetic material; and auxiliary permanent magnets having a magnetizing direction that is orthogonal both to the rotation axis direction of the rotor and a radial direction of the rotor, and arranged on both sides of the partition member in the rotation axis direction of the rotor.
US08283825B2 Auxiliary bearing system with plurality of inertia rings for magnetically supported rotor system
An auxiliary bearing system for supporting a rotating shaft including a first auxiliary bearing coupled to the rotating shaft. A first inertia ring is coupled to and circumscribes the first auxiliary bearing. A second inertia ring circumscribes the first inertia ring. A radial clearance is defined between the first and second inertia rings when the rotating shaft is supported by a primary bearing system, and the first inertia ring engages the second inertia ring when the rotating shaft is not supported by the primary bearing system. A second auxiliary bearing is engaged with an outer surface of the second inertia ring.
US08283822B2 Small-sized motor
A connection circuit board includes a main portion and a lead wire connecting portion. The main portion is positioned between an end portion of a motor case body and an end bracket. The lead wire connecting portion projects outwardly from the motor case body. A protective cap including a connecting portion receiving chamber for receiving the lead wire connecting portion of the connection circuit board is attached to the lead wire connecting portion through an engaging structure. An adhesive is filled in the connecting portion receiving chamber of the protective cap. In a small-sized motor of the above configuration, the protective cap can securely be fixed to the motor case.
US08283819B2 Voltage adjuster for AC generator for vehicle
In a voltage adjuster for a vehicle AC generator which has a cooing member for cooling a circuit portion of the voltage adjuster and in which plural fins of the cooling member are disposed so as to face an air suction hole formed in a case, the cooling member is constructed by assembling a first cooling plate having the same cross-sectional surface in a generating and processing direction and at least a second cooling plate having the same cross-sectional surface in a generating and processing direction and the same cross-sectional surface shape as the first cooling plate, and the fin end surfaces of one cooling plate are abutted on the other cooling plate so as to face the ventilation paths formed by the plural fins of the other cooling plate.
US08283818B2 Electric motor with heat pipes
A motor that includes a motor portion structured to house a stator and a rotor mounted to a shaft of the motor. The motor additionally includes a cooling portion disposed adjacent to the motor portion and separated from the motor portion by a structural interface. The cooling portion provides a cooling chamber structured to have a cooling fluid passed therethrough via a cooling fluid moving device that is structured to be coupled to and driven by the motor shaft. Furthermore, the motor includes a plurality of heat pipes having evaporator ends disposed within the motor portion and condenser ends disposed within the cooling chamber. During operation of the motor and cooling fluid moving device, the cooling fluid contacts the heat pipe condenser ends to extract heat from the condenser ends, hence cooling the evaporator ends of the heat pipes, thereby cooling the motor portion of the motor and the stator and rotor housed therein.
US08283817B2 Electric machine having a twin axial fan
An electric machine with improved cooling efficiency includes a stator, a rotor operating as a rotor fan and comprising a shaft defining an axial direction and having radial and axial cooling channels, and an axial fan configured as a twin axial fan and arranged coaxially with the shaft and supplying a coolant to the axial cooling channels. The axial fan has first and second blade rings and a funnel-shaped tube with a smaller opening directly connected to the axial cooling channels of the rotor to deliver coolant to the axial cooling channels of the rotor, and a larger opening, which is non-rotatably connected to and encloses the first blade ring. The second blade ring is firmly attached at an outer circumference of the funnel-shaped tube to deliver the coolant to the stator. Both the stator and the rotor can be cooled using an efficient coolant flow.
US08283816B2 Superconducting apparatus and vacuum container for the same
A vacuum container for housing therein a superconducting apparatus includes first and second partition walls made of magnetic-permeable nonmetallic materials, respectively, and facing each other to form a vacuum heat insulation chamber that is adapted to cover a superconductor that generates a magnetic flux. The first and second partition walls are exposed to relatively higher and lower temperatures, respectively. The first partition wall includes a radiation surface emitting thermal radiation while the second partition wall includes an absorption surface absorbing the thermal radiation. One of the radiation surface and the absorption surface is provided with a metal layer group in an exposed manner relative to the other of the radiation surface and the absorption surface. The metal layer group includes a plurality of metal layers spaced apart from one another and the nonmetallic material appears between the plurality of metal layers.
US08283815B2 Electrical machine
The invention relates to an electrical machine (1, 110), which is in particular a synchronous machine, which has a primary part (3, 130) and a secondary part (5, 120), wherein the primary part (3, 130) has a) a first means (9) for producing a first magnetic field and b) a further means (17, 27, 29) for producing a further magnetic field, which in particular is an exciter field, and wherein the first means (9) has at least one winding, and the further means (17, 27, 29) is arranged in the region of an active air gap (21) of the electrical machine between the primary part and the secondary part and has magnetic poles, each having at least one permanent magnet (17).
US08283813B2 Robot drive with magnetic spindle bearings
A drive section for a substrate transport arm including a frame, at least one stator mounted within the frame, the stator including a first motor section and at least one stator bearing section and a coaxial spindle magnetically supported substantially without contact by the at least one stator bearing section, where each drive shaft of the coaxial spindle includes a rotor, the rotor including a second motor section and at least one rotor bearing section configured to interface with the at least one stator bearing section, wherein the first motor section is configured to interface with the second motor section to effect rotation of the spindle about a predetermined axis and the at least one stator bearing section is configured to effect at least leveling of a substrate transport arm end effector connected to the coaxial spindle through an interaction with the at least one rotor bearing section.
US08283806B2 High voltage power supply
A high voltage power supply (HVPS) including first and second high voltage output controllers controlling output of a high voltage output signal; and a plurality of transformers transforming an output signal provided from the first and second high voltage output controller, disposed outside of the first and second high voltage controllers on the substrate, wherein output terminals in the secondary sides of the plurality of transformers are disposed along the edge of the substrate. Therefore, the volume of a system can be minimized by arranging circuits in each component for high voltage output in parallel, and spark and discharge can be reduced by minimizing interference between the primary sides and the secondary sides of the components for high voltage output, thereby preventing damage to a product.
US08283805B2 Scanner with battery
Power is provided to a scanning device. Power supplied by an attached bus is used to power the scanning device when power requirements for the scanning device can be met by the power supplied by the attached bus. Power is drawn from a rechargeable battery to supply power to the scanning device when power requirements for the scanning device cannot be met by the power from the attached bus. When the scanning device is in a stand-by mode, the power from the attached bus is used to recharge the rechargeable battery.
US08283797B2 Power control system and method
This invention discloses a power control system comprising a prime mover and a generator driven by the prime mover. A control device is coupled with the generator to ascertain a change in speed of the generator and vary an output power of the generator according to the change. The control device applies a signal to reduce the generator output power and another signal to restore the generator output power. The power control system may include a transmission, a speed converter, and/or an accessory.
US08283796B2 Hybrid engine installation and a method of controlling such an engine installation
A hybrid engine installation (200) includes drive element (204) suitable for driving a mechanical element (BTP, BTA) in rotation. In addition, the hybrid engine installation is remarkable in that it includes at least one gas turbine (253, 254) and at least one electric motor (201) mechanically linked to the drive element (204) to drive it in rotation.
US08283795B2 Mechanical motion charging system on an electric vehicle
A system in an electric vehicle converts the mechanical energy resulting from movement of the vehicle chassis to electric energy. The system has one or more energy conversion units including an alternator with a rotatable shaft and a weighted fly wheel fixed to the shaft. A female receptor on an end of the alternator shaft is disposed in spaced, axial alignment with a male driver on the end of a spiral ratcheting shaft that is operatively engaged with a pivoting lever and the chassis of the vehicle, whereupon upward and downward motion of the chassis frame causes the male driver to move between engagement and disengagement with the female receptor. A ratchet mechanism drives rotation of the spiral ratcheting shaft upon engagement of the male driver with the female receptor, thereby rotating the female receptor, flywheel and alternator shaft. The male driver disengages from the female receptor, allowing the fly wheel and alternator shaft to freely rotate in order to generate electric energy which is used to continuously charge a bank of batteries for powering the electric vehicle.
US08283793B2 Device for energy harvesting within a vessel
An energy harvesting device is provided that may include any of a number of features. One feature of the energy harvesting device is that it is adapted for insertion into a human blood vessel for converting pulsatile pressure in the blood vessel into electrical energy. The energy harvesting device can provide electrical energy to another electronic or electromechanical on or in the human body. The energy harvesting device can include an electrostatic generator. Methods associated with use of the energy harvesting device are also covered.
US08283780B2 Surface mount semiconductor device
A surface mount semiconductor device has a semiconductor die encapsulated in a molding compound. Electrical contact elements of an intermediate set are disposed on the molding compound. A set of coated wires electrically connect bonding pads of the semiconductor die and the electrical contact elements of the intermediate set. A layer of insulating material covers the coated wires, the die and the electrical contact elements of the intermediate set. Electrically conductive elements are exposed at an external surface of the layer of insulating material and contact respective electrical contact elements of the intermediate set through the layer of insulating material.
US08283779B2 Peel-resistant semiconductor device with improved connector density, and method of manufacturing the same
A semiconductor device includes a substrate and a plurality of bumps. The substrate is compartmentalized into a bump-free area provided along four sides of the substrate and a bump area which is surrounded by the bump-free area. The plurality of bumps is aligned in the bump area. The plurality of bumps includes a first group of bumps aligned along the four sides and a second group of bumps surrounded by the first group. A first subgroup of bumps included in the first group and aligned along one side of the four sides is shifted with respect to a second subgroup of bumps included in the first group and aligned along an opposing side of the four sides in a direction parallel to the one side.
US08283759B2 Lead frame having outer leads coated with a four layer plating
A lead frame base is coated with a four-layer plating. The four-layer plating includes an underlayer plating (Ni), a palladium plating, a silver plating and a gold plating arranged in this order from bottom to top.
US08283756B2 Electronic component with buffer layer
An electronic component includes a metal substrate, a semiconductor chip configured to be attached to the metal substrate, and a buffer layer positioned between the metal substrate and the semiconductor chip configured to mechanically decouple the semiconductor chip and the metal substrate. The buffer layer extends across less than an entire bottom surface of the semiconductor chip.
US08283755B2 Multichip semiconductor device, chip therefor and method of formation thereof
A multichip semiconductor device is disclosed in which chips are stacked each of which comprises a semiconductor substrate formed on top with circuit components and an interlayer insulating film formed on the top of the semiconductor substrate. At least one of the chips has a connect plug of a metal formed in a through hole that passes through the semiconductor substrate and the interlayer insulating film. The chip with the connect plug is electrically connected with another chip by that connect plug.
US08283752B2 Semiconductor device
In a semiconductor device, a first semiconductor chip includes a first circuit and a first inductor, and a second semiconductor chip includes a second circuit and chip-side connecting terminals. An interconnect substrate is placed over the first semiconductor chip and the second semiconductor chip. The interconnect substrate includes a second inductor and substrate-side connecting terminals. The second inductor is located above the first inductor. The chip-side connecting terminals and the two substrate-side connecting terminals are connected through first solder balls.
US08283747B2 Semiconductor device and fabrication method of the same
A semiconductor device including a first conduction type semiconductor layer; a second conduction type element forming region formed above the first conduction type semiconductor layer and formed with at least one semiconductor element formed on a surface region of the second conduction type element forming region; a first conduction type element-isolation region insulating and segregating the second conduction type element forming region from the exterior; and a second conduction type buried region formed at the interface of the first conduction type semiconductor layer and the second conduction type element forming region, formed separated from the first conduction type element-isolation region. In the semiconductor device a second conduction type high concentration region is buried in the surface of the second conduction type element forming region and formed to surround the semiconductor element and separated from the first conduction type element-isolation region.
US08283745B2 Method of fabricating backside-illuminated image sensor
Provided is a method of fabricating a backside illuminated image sensor that includes providing a device substrate having a frontside and a backside, where pixels are formed at the frontside and an interconnect structure is formed over pixels, forming a re-distribution layer (RDL) over the interconnect structure, bonding a first glass substrate to the RDL, thinning and processing the device substrate from the backside, bonding a second glass substrate to the backside, removing the first glass substrate, and reusing the first glass substrate for fabricating another backside-illuminated image sensor.
US08283744B2 Molybdenum-doped indium oxide structures and methods
Methods of forming transparent conducting oxides and devices formed by these methods are shown. Monolayers that contain indium and monolayers that contain molybdenum are deposited onto a substrate and subsequently processed to form molybdenum-doped indium oxide. The resulting transparent conducing oxide includes properties such as an amorphous or nanocrystalline microstructure. Devices that include transparent conducing oxides formed with these methods have better step coverage over substrate topography and more robust film mechanical properties.
US08283738B2 Semiconductor device including sensor member and cap member and method of making the same
A semiconductor device includes a sensor member and a cap member. The sensor member has a surface and includes a first sensing section. The first sensing section includes first and second portions that are located on the surface side of the sensor member and electrically insulated from each other. The cap member has a surface and includes a cross wiring portion. The surface of the cap member is joined to the surface of the sensor member in such a manner that the first sensing section is sealed by the sensor member and the cap member. The cross wiring portion electrically connects the first portion to the second portion.
US08283727B1 Circuit with electrostatic discharge protection
A circuit with electrostatic discharge protection is described. In one case, the circuit includes trigger device configured to protect a component connected to a node of the circuit during an electrostatic discharge event, the trigger device includes an isolation structure interposed between a gate oxide layer and an extended drain region. A portion of the extended drain region proximate the isolation structure is substantially metal-free.
US08283723B2 MOS device with low injection diode
A semiconductor device is formed on a semiconductor substrate. The device includes a drain, an epitaxial layer overlaying the drain, and an active region. The active region includes a body disposed in the epitaxial layer, having a body top surface, a source embedded in the body, extending from the body top surface into the body, a gate trench extending into the epitaxial layer, a gate disposed in the gate trench, an active region contact trench extending through the source and into the body, an active region contact electrode disposed within the active region contact trench, wherein a thin layer of body region separating the active region contact electrode from the drain.
US08283722B2 Semiconductor device having an enhanced well region
An apparatus is disclosed to increase a breakdown voltage of a semiconductor device. The semiconductor device includes an enhanced well region to effectively increase a voltage at which punch-through occurs when compared to a conventional semiconductor device. The enhanced well region includes a greater number of excess carriers when compared to a well region of the conventional semiconductor device. These larger number of excess carriers attract more carriers allowing more current to flow through a channel region of the semiconductor device before depleting the enhanced well region of the carriers. As a result, the semiconductor device may accommodate a greater voltage being applied to its drain region before the depletion region of the enhanced well region and a depletion region of a well region surrounding the drain region merge into a single depletion region.
US08283719B2 Nonvolatile memory device having a fixed charge layer
Provided are a nonvolatile memory device and a method for fabricating the same. The nonvolatile memory device may include a stacked structure, a semiconductor pattern, an information storage layer, and a fixed charge layer. The stacked structure may be disposed over a semiconductor substrate. The stacked structure may include conductive patterns and interlayer dielectric patterns alternately stacked therein. The semiconductor pattern may be connected to the semiconductor substrate by passing through the stacked structure. The information storage layer may be disposed between the semiconductor pattern and the conductive patterns. The fixed charge layer may be disposed between the semiconductor pattern and the interlayer dielectric pattern. The fixed charge layer may include fixed charges. Electrical polarity of the fixed charges may be equal to electrical polarity of majority carriers of the semiconductor pattern.
US08283718B2 Integrated circuit system with metal and semi-conducting gate
A method for forming an integrated circuit system is provided including forming a semi-conducting layer over a substrate, forming a spacer stack having a gap filler adjacent to the semi-conducting layer and a inter-layer dielectric over the gap filler, forming a transition layer having a recess over the semi-conducting layer and adjacent to the spacer stack, and forming a metal layer in the recess.
US08283714B2 Semiconductor memory device having vertical channel transistor and method for fabricating the same
Channels of two transistors are vertically formed on portions of two opposite side surfaces of one active region, and gate electrodes are vertically formed on a device isolation layer contacting the channels of the active region. A common bit line contact plug is formed in the central portions of the active region, two storage node contact plugs are formed on both sides of the bit line contact plug, and an insulating spacer is formed on a side surface of the bit line contact plug. A word line, a bit line, and a capacitor are sequentially stacked on the semiconductor substrate, like a conventional semiconductor memory device. Thus, effective space arrangement of a memory cell is possible such that a 4F2 structure is constituted, and a conventional line and contact forming process can be applied such that highly integrated semiconductor memory device is readily fabricated.
US08283713B2 Logic-based eDRAM using local interconnects to reduce impact of extension contact parasitics
An electronic device includes an active layer located over a substrate with the active layer having a logic circuit and an eDRAM cell. The electronic device also includes a first metallization level located over the active layer that provides logic interconnects and metal capacitor plates. The logic interconnects are connected to the logic circuit and the metal capacitor plates are connected to the eDRAM cell. The electronic device additionally includes a second metallization level located over the first metallization level that provides an interconnect connected to at least one of the logic interconnects, and a bit line that is connected to the eDRAM cell. A method of manufacturing an electronic device is also included.
US08283711B2 Non-volatile memory devices having data storage layer
Provided are a non-volatile memory device, which may have a stacked structure and may be easily integrated at increased density, and a method of fabricating and using the non-volatile memory device. The non-volatile memory device may include at least one pair of first electrode lines. At least one second electrode line may be between the at least one pair of first electrode lines. At least one data storage layer may be between the at least one pair of first electrode lines and the at least one second electrode line and may locally store a resistance change.
US08283708B2 Semiconductor devices and methods of forming semiconductor devices having diffusion regions of reduced width
Semiconductor devices and methods for forming semiconductor devices are provided, including semiconductor devices that comprise one or more diffusion region in a semiconductor, the one or more diffusion regions being adjacent to a gate formed adjacent to a surface of the semiconductor (e.g., a semiconductor substrate). The one or more diffusion regions comprise a first width at a depth below the surface of the semiconductor and a second width near the surface of the semiconductor, the second width of the one or more diffusion regions being less than about 40% greater than the first width.
US08283707B2 Reduction of threshold voltage instabilities in a MOS transistor
A MOS transistor includes an etch stop layer presenting a density of less than a determined threshold value, below which the material of said stop layer is permeable to molecules of dihydrogen and/or water. The material may comprise a nitride. A material used for the etch stop layer preferably has a density value of less than about 2.4 g/cm3.
US08283706B2 Optimization of critical dimensions and pitch of patterned features in and above a substrate
A die is formed with different and optimized critical dimensions in different device levels and areas of those device levels using photolithography and etch techniques. One aspect of the invention provides for a memory array formed above a substrate, with driver circuitry formed in the substrate. A level of the memory array consists of, for example, parallel rails and a fan-out region. It is desirable to maximize density of the rails and minimize cost of lithography for the entire memory array. This can be achieved by forming the rails at a tighter pitch than the CMOS circuitry beneath it, allowing cheaper lithography tools to be used when forming the CMOS, and similarly by optimizing lithography and etch techniques for a device level to produce a tight pitch in the rails, and a more relaxed pitch in the less-critical fan-out region.
US08283703B2 Solid state Klystron
A solid state Klystron structure is fabricated by forming a source contact and a drain contact to both ends of a conducting wire and by forming a bias gate and a signal gate on the conducting wire. The conducting wire may be at least one carbon nanotube or at least one semiconductor wire with long ballistic mean free paths. By applying a signal at a frequency that corresponds to an integer multiple of the transit time of the ballistic carriers between adjacent fingers of the signal gate, the carriers are bunched within the conducting wire, thus amplifying the current through the solid state Klystron at a frequency of the signal to the signal gate, thus achieving a power gain.
US08283701B2 Semiconductor device with dynamic array sections defined and placed according to manufacturing assurance halos
An integrated circuit device includes a plurality of dynamic array sections, each of which includes three or more linear conductive segments formed within its gate electrode level in a parallel manner to extend lengthwise in a first direction. An adjoining pair of dynamic array sections are positioned to have co-located portions of outer peripheral boundary segments extending in the first direction. At least one of the linear conductive segments within the gate electrode level of a given dynamic array section is a non-gate linear conductive segment that does not form a gate electrode of a transistor. The non-gate linear conductive segment of either of the adjoining pair of dynamic array sections spans the co-located portion of outer peripheral boundary segment toward the other of the adjoining pair of dynamic array sections, and is contained within gate electrode level manufacturing assurance halo portions of the adjoining pair of dynamic array sections.
US08283700B2 Field effect transistor and manufacturing method thereof
A field effect transistor includes a channel layer of group-III nitride-based compound semiconductor; an interface layer formed on the channel layer and of AlXInYGa1-X-YN, where 0≦X≦1, 0≦Y≦1, and X+Y≦1, which is different from material of the channel layer, an electron supplying layer of group-III nitride-based compound semiconductor formed on the interface layer, the electron supplying layer having a recess that reaches the interface layer; a source electrode and a drain electrode formed on the electron supplying layer on respective sides of the recess; an insulating film formed on an inner surface of the recess; and a gate electrode formed on the insulating film.
US08283698B2 Electrostatic discharge protection
An electrostatic discharge (ESD) protection circuit for protecting an integrated circuit (IC) having a first voltage potential, a first power supply potential and a second power supply potential. The ESD circuit includes a first NPN bipolar transistor having a first N-doped junction, a second N-doped junction and a third P-doped base junction. The first N-doped junction is coupled to the first voltage potential and the second N-doped junction is coupled to the first power supply potential. The ESD circuit also includes a first PNP bipolar transistor having a first P-doped junction, a second P-doped junction and a third N-doped base junction. The first P-doped junction is coupled to the first voltage potential and the second P-doped junction is coupled to the second power supply potential. The third P-doped base junction of the first NPN bipolar transistor is coupled to the third N-doped base junction of the first PNP bipolar transistor.
US08283697B2 Internal combustion engine igniter semiconductor device
An internal combustion engine igniter semiconductor device is disclosed which is low cost yet secures energy withstand and reverse surge withstand capability. An IGBT includes a clamping diode between a collector electrode and a gate electrode. The IGBT has two n-type buffer layers of differing impurity concentrations between a p+ substrate and an n-type base layer of the IGBT, wherein the total thickness of the two-layer buffer layer is 50 μm or less, and the overall impurity amount is 20×1013 cm−2 or less.
US08283686B2 Side emitting device with hybrid top reflector
A side-emitting light emitting device (100) is provided, comprising at least one light emitting diode (101) arranged on a substrate (102) and facing a scattering reflector (103, 109) disposed at a distance from and extending along the extension of said substrate. The scattering reflector comprises scattering components (110) distributed in a carrier (108), and the scattering components have a refractive index being different from the refractive index of said carrier. The scattering action of the reflector gives rise to an angular redistribution in the device, which increases the chance of light exiting the device through lateral openings between the reflector and the substrate, while light is essentially prevented from being emitted through the top surface.
US08283685B2 Light-generating arrangement
The invention relates to a light-generating arrangement comprising a light-emitting semiconductor element provided with electric supply lines and a transparent light-directing element (2) which is arranged upstream of the semiconductor element in the emission direction at a distance therefrom and which is used for concentrating the light emitted by said semiconductor element in such a way that a light stream is formed. The light output surface (4) of the light-directing element (2) comprises a microstructure (6) consisting of a plurality of elevations and cavities deviating the trajectory of the light stream by <5°.
US08283683B2 Chip-bonding light emitting diode chip
A light emitting diode chip includes a permanent substrate having a holding space formed on the permanent substrate; an insulating layer and a metal layer sequentially formed on the permanent substrate and the holding spacer; a die having a eutectic layer and a light-emitting region and bonded to the metal layer within the holding space via the eutectic layer coupling to the metal layer; a filler structure filled between the holding space and the die; and an electrode formed on the die and in contact with the light-emitting region.
US08283672B2 Semiconductor devices having gallium nitride epilayers on diamond substrates
Methods for integrating wide-gap semiconductors with synthetic diamond substrates are disclosed. Diamond substrates are created by depositing synthetic diamond onto a nucleating layer deposited or formed on a layered structure including at least one layer of gallium nitride, aluminum nitride, silicon carbide, or zinc oxide. The resulting structure is a low stress process compatible with wide-gap semiconductor films, and may be processed into optical or high-power electronic devices. The diamond substrates serve as heat sinks or mechanical substrates.
US08283670B2 Liquid crystal display panel and fabricating method thereof
A liquid crystal display panel includes: a thin film transistor array substrate having a gate line and a data line provided on the substrate; a gate insulating film between the gate line and the data line; a thin film transistor having a source electrode, a drain electrode and a gate electrode; a pixel electrode; a protective film for protecting the thin film transistor; a plurality of pads; a transparent electrode pattern formed on the data line, source electrode and drain electrode; and a color filter array substrate joined to the thin film transistor array substrate so that the color filter substrate does not overlap the pad area of the thin film transistor array substrate, wherein at least one of the gate insulating film and protective film in the pad area is etched using the color filter array substrate as a mask to expose at least one of the plurality of pads.
US08283669B2 Semiconductor device and method of manufacturing same
An object is to reduce the adverse influence which a portion of a gate insulating layer where the thickness has decreased, that is, a step portion, has on semiconductor element characteristics so that the reliability of the semiconductor element is improved. A semiconductor layer is formed over an insulating surface; a side surface of the semiconductor layer is oxidized using wet oxidation to form a first insulating layer; a second insulating layer is formed over the semiconductor layer and the first insulating layer; and a gate electrode is formed over the semiconductor layer and the first insulating layer with the second insulating layer interposed therebetween.
US08283667B2 Thin film transistor
A thin film transistor is provided, which includes a gate electrode layer over a substrate, a gate insulating layer over the gate electrode layer, a layer including an amorphous semiconductor over the gate insulating layer, a pair of crystal regions over the layer including the amorphous semiconductor, and source and drain regions over and in contact with the pair of crystal regions. The source and drain regions include a microcrystalline semiconductor layer to which an impurity imparting one conductivity type is added.
US08283664B2 Disguising test pads in a semiconductor package
A method of forming a semiconductor package is disclosed including disguising the test pads. Test pads are defined in the conductive pattern of the semiconductor package for allowing electrical test of the completed package. The test pads are formed in shapes such as letters or objects so that they are less recognizable as test pads.
US08283662B2 Memory device
A memory device without additional logic circuits, including a memory cell which cannot be accessed by a third party and which is always accessible when needed. One embodiment is a memory device including a first memory cell and a second memory cell, and the second memory cell includes a second transistor having a second channel formed of an oxide semiconductor film. Data is read from the second memory cell when the second transistor is being irradiated with ultraviolet rays.
US08283661B2 Organic EL display and method for manufacturing same
Provided is an organic EL display manufacturing method which has: a step wherein an organic EL panel having a substrate and organic EL elements arranged in matrix on the substrate is prepared, and each organic EL element is permitted to have a pixel electrode disposed on the substrate, an organic layer disposed on the pixel electrode, a transparent counter electrode disposed on the organic layer, a sealing layer disposed on the transparent counter electrode, and a color filter disposed on the sealing layer; a step of detecting a defective portion on the organic layer in the organic EL element; and a step of breaking the transparent counter electrode in a region on the defective portion of the transparent counter electrode by irradiating the region on the defective portion with a laser beam. The laser beam is radiated by being tilted with respect to the normal line on the display surface of the organic EL panel.
US08283659B2 Tetrahydrotetraazapentacenes in thin-film transistors
Compounds of Formula (I) are disclosed: wherein R1-R14, x, y, and z are as defined herein. The compounds are useful as semiconducting materials for electronic devices such as thin-film transistors.
US08283649B2 Memristor with a non-planar substrate
A memristor includes a substrate having a plurality of protrusions, wherein each of the plurality of protrusions extends in a first direction, a first electrode provided over at least one of the plurality of protrusions, wherein the first electrode conforms to the shape of the at least one protrusion such that the first electrode has a crest, a switching material positioned upon the first electrode; and a second electrode positioned upon the switching material such that a portion of the second electrode is substantially in line with the crest of the first electrode along the first direction, wherein an active region in the switching material is operable to be formed between the crest of the first electrode and the portion of the second electrode that is substantially in line with the crest of the first electrode.
US08283648B2 Resistance variable memory cell
Methods, devices, and systems associated with phase change memory structures are described herein. One or more embodiments of the present disclosure can reduce thermal crosstalk associated with phase change memory cells, which can provide various benefits including improved data reliability and retention and decreased read and/or write times, among various other benefits. One or more embodiments can reduce the number of processing steps associated with providing local interconnects to phase change memory arrays.
US08283647B2 Developer liquid level sensor
An apparatus for detecting developer liquid (108) level in a plate developer section tank (104) includes a reflective surface (204) installed on at least on one edge of the developer tank; a light emitter (232) which emits light onto the reflective surface; a light detector (236) adapted to detect reflected light from the reflective surface, wherein the light emitter and the light detector are positioned relative to the reflective surface such that the emitted light from the light emitter is deflected by the developer liquid hitting the reflective surface at 90 degrees.
US08283643B2 Systems and methods for drive laser beam delivery in an EUV light source
An EUV light source device is described herein which may comprise a laser beam travelling along a beam path, at least a portion of the beam path aligned along a linear axis; a material for interaction with the laser beam at an irradiation site to create an EUV light emitting plasma; a first reflector having a focal point, the first reflector positioned with the focal point on the linear axis, the first reflector receiving laser light along the beam path; and a second reflector receiving laser light reflected by the first reflector and directing the laser light toward the irradiation site.
US08283636B2 Thermally excited near-field source
A high resolution material observation system includes an object having at least one spatial dimension sufficient to support production of near-field infrared emissions, a holder adapted to receive a sample to be observed, the holder further adapted to position the sample in the near-field infrared emissions, and a thermal excitation unit, adapted to be thermally coupled to at least one of the object and the sample. The thermal excitation unit is further adapted to causing black body radiation in either the object or the sample within the infrared spectrum.
US08283634B2 Device for detecting electromagnetic radiation
The invention relates to a device for detecting electromagnetic radiation comprising: a resistive bolometer, a biasing circuit capable of biasing said bolometer with a predetermined bias voltage, a rejection module capable of generating a common mode current, a measuring circuit capable of being connected to a bolometer and a rejection module in order to measure the difference between the current flowing through the bolometer when it is biased and the common mode current generated by the rejection module. According to the invention, rejection module comprises: a module for estimating a current that flows through resistive bolometer when it is subjected to the bias voltage and made insensitive to the electromagnetic radiation; and a current generator which is controlled by the estimation module and generates the current estimated by the latter as a common mode current.
US08283633B2 Tuning D* with modified thermal detectors
Disclosed is apparatus and methodology for producing thermal detectors with spectral responsivities that mimic the absorptions of chemical analytes, and whose detector characteristics approach those of conventional broad-band thermal detectors. In an exemplary arrangement, the methodology provides for modification of a known Si-based thermal detector by adding a near-infrared dye absorbing film above a reflector deposited directly on the thermal detector element. The method is general to all types of thermal detectors that can be divided into separate absorber and thermal sensor components.
US08283630B2 Method and apparatus for measuring dimension of circuit pattern formed on substrate by using scanning electron microscope
In the dimension measurement of a circuit pattern using a scanning electron microscope (SEM), in order to make it possible to automatically image desired evaluation points (EPs) on a sample, and automatically measure the circuit pattern formed at the evaluation points, according to the present invention, in the dimension measurement of a circuit pattern using a scanning electron microscope (SEM), it is arranged that coordinate data of the EP and design data of the circuit pattern including the EP are used as an input, creation of a dimension measurement cursor for measuring the pattern existing in the EP and selection or setting of the dimension measurement method are automatically performed based on the EP coordinate data and the design data to automatically create a recipe, and automatic imaging/measurement is performed using the recipe.
US08283629B1 Aberration-corrected wien ExB mass filter with removal of neutrals from the Beam
A mass filter for an ion beam system includes at least two stages and reduces chromatic aberration. One embodiment includes two symmetrical mass filter stages, the combination of which reduces or eliminates chromatic aberration, and entrance and exit fringing field errors. Embodiments can also prevent neutral particles from reaching the sample surface and avoid crossovers in the beam path. In one embodiment, the filter can pass a single species of ion from a source that produces multiple species. In other embodiments, the filter can pass a single ion species with a range of energies and focus the multi-energetic ions at the same point on the substrate surface.
US08283625B2 Method of preparing sample for matrix-assisted laser desorption ionization mass spectrometry and matrix-assisted laser desorption ionization mass spectrometry
It is intended to provide a method of preparing sample for matrix-assisted laser desorption/ionization mass spectrometry using a matrix capable of generating preferred crystals that cause effective ionization of a molecule to be measured. A method of preparing a sample for matrix-assisted laser desorption/ionization mass spectrometry comprising the steps of: preparing a solution of 2,5-dihydroxybenzoic acid of 40 mg/mL to saturated concentration as a matrix solution; and dispensing the matrix solution to a sample to be analyzed by using an inkjet mechanism, to crystallize the 2,5-dihydroxybenzoic acid.
US08283624B2 Apparatus and method for elemental analysis of particles by mass spectrometry
An apparatus for elemental analysis of particles such as single cells or single beads by mass spectrometry is described. The apparatus includes means for particle introduction; means to vaporize, atomize and ionize elements associated with a particle; means to separate the ions according to their mass-to-charge ratio; means to detect the separated ions, means to digitize the output of the means to detect the ions; means to transfer and/or to process and/or record the data output of the means to digitize, having means to detect the presence of a particle in a mass spectrometer; and means to synchronize one of the means for ion detection, data digitization, transfer, processing and recording with the means to detect the presence of a particle. Methods and computer readable code implementing aspects of the apparatus, and for reducing the rates of data generation, digitization, transfer, processing and recording are also described.
US08283623B2 Robust spectral analyzer for one-dimensional and multi-dimensional data analysis
A method of analyzing a spectrum of one-dimensional or multi-dimensional signal X(t) requires a number of steps including deriving coefficients [AN(ω), BN(ω)] of an Lp-norm harmonic regression of tie signal with 0
US08283622B2 Method and apparatus for testing magnetic properties of magnetic media
A method and apparatus for testing a magnetic medium. The method comprises applying a magnetic field of a time-varying strength; directing a polarized optical beam towards a portion of the medium that is in the magnetic field, wherein the optical beam is reflected by a surface of the medium at a point of incidence in the magnetic field; moving the medium relative to the optical beam so as to cause the point of incidence to repeatedly traverse each of a plurality of sectors along a track on the surface; obtaining a series of Kerr signal measurements of the reflected optical beam; grouping measurements into ensembles such that the measurements in an individual ensemble are those obtained while the point of incidence was in a corresponding one of the sectors; and determining at least one magnetic property of at least one of the sectors from the measurements in the corresponding ensemble.
US08283618B2 Method and device for reading electrical charges produced by a photo-detector, and detector comprising such devices
A method of reading electrical charges produced by a photo-detector of a photo-detector matrix includes collecting and storing electrical charges produced by the photo-detector in a first capacitive element, transferring the charges stored in the first capacitive element to a second capacitive element, and reading the voltage at the terminals of the second capacitive element. The transfer followed by the reading is carried out in at least two phases: at least one first phase taking place during the collection and storage of the charges in the first capacitive element, and a second phase taking place at the end of the collection and storage of the electrical charges in the first capacitive element.
US08283616B2 Method and apparatus for microwave dissociation of organic compounds
The invention describes a process for reducing an organic-containing material into lower molecular weight gaseous hydrocarbons, liquid hydrocarbons and solid carbon constituents, by using out-of-phase microwaves which enter the applicator through at least one applicator diffuser matrix. The matrix includes essentially parallel beveled entry channels.
US08283615B1 Permanent magnet air heater
A permanent magnet air heater has a housing with an internal chamber accommodating an electric motor rotating a fan to move air through the housing. A non-ferrous member having bores for cylindrical magnets and a steel member with a copper plate secured to the steel member are rotated relative to each other by the motor whereby the magnetic field between the magnets and copper plate generates heat which is transferred to air in the housing moving through the housing by the fan.
US08283614B2 Apparatuses useful in printing and methods of fixing marking materials onto media
Apparatuses useful for printing and methods of fixing marking materials onto media are disclosed. An exemplary embodiment of the apparatuses useful in printing includes a first member including a first surface; a second member comprising at least one ferromagnetic material having a relative magnetic permeability greater than 1, a susceptor over the at least one ferromagnetic material, the susceptor comprising at least one electrically resistive metal, and a second surface over the at least one ferromagnetic material and the susceptor, the second surface forming a nip with the first surface at which media are received; and a magnetic field generator for generating a magnetic field to inductively heat the second member.
US08283609B2 On die thermal sensor in semiconductor memory device
An on die thermal sensor in a semiconductor memory device includes: a reference voltage generating unit for generating a band gap voltage and generating a reference voltage by using the base band gap voltage; a voltage amplifying unit for outputting a temperature voltage by amplifying the band gap voltage; and a temperature information code generating unit for generating a temperature information code corresponding to a voltage level of the temperature voltage, wherein voltage variation of the temperature voltage is amplified as much as a preset amplifying value and a maximum voltage level of the temperature voltage is maintained lower than that of a power supply voltage used in the semiconductor memory device.
US08283608B2 Method for heating at least one component of an SCR system using resistive heating elements
Method for heating at least one component of an SCR system using several resistive heating elements, according to which these heating elements are fed in parallel by a current source and according to which a current sensor is placed in series with the current source and all the resistors, which are connected in parallel.
US08283604B2 Chip warmer
A chip warming device (10, 1000, 2000) is provided with a support structure (15) and a heating device. The support structure (15) has a first door (100) that selectively seals a first opening (60), a second door (110) that selectively seals a second opening (70) and a chip tray (120) that selectively seals a third opening (80). The heating device is positioned in the support structure (15) that supplies heat to the chips. The first and second openings (60, 70) are adjacent to each other. The second door (110) can be at an angle with respect to vertical when in a closed position. The chip tray (120) can be at an angle with respect to vertical when in a closed position. The support structure (15) can have a floor that is at an angle with respect to horizontal. An antimicrobial coating or treatment can be used on at least a portion of the support structure (15) for suppression of microbe growth.
US08283599B2 Welding method for T-joint
In a plate assembling step, a gap (5) is formed between a leading end portion (3A) of a groove (3) provided on an upright plate (2) and a lower plate (1). An arc is generated from a welding wire (7) toward a back surface (3C) side of the groove (3) through the gap (5), to form a satisfactory penetration bead (8) on the back surface (3C) side of the groove (3). Next, the welding wire (7), the lower plate (1), the groove (3) of the upright plate (2) and the penetration bead (8) are fused to form a first-layer welding bead (9), thereby firmly joining the lower plate (1) and the groove (3) of the upright plate (2). The first and second welding steps are performed continuously after performing the plate assembling step, to enhance workability at the time of welding the lower plate (1) and the upright plate (2).
US08283596B2 Laser processing apparatus and laser processing method, debris collection mechanism and debris collection method, and method for producing display panel
A laser processing apparatus is provided for patterning with laser light a resin film or a metal film formed on a substrate. The apparatus includes a laser light source; and a debris collection device having a transmission window through which the laser light is transmitted, a vortex generation mechanism generating a vortex gas flow by allowing gas to flow into a region near a laser light-irradiated area of the resin film or the metal film, and a screening device having an opening through which the incident laser light passes and screening a flow of debris. The mechanism is placed close to the resin film or the metal film on the substrate. Debris generated by laser light irradiation and before and after being stacked on the object film is entrained in the vortex gas flow generated by the vortex generation mechanism and is exhausted to outside through the screening device.
US08283595B2 Laser processing method and laser processing apparatus
A laser beam machining method and a laser beam machining device capable of cutting a work without producing a fusing and a cracking out of a predetermined cutting line on the surface of the work, wherein a pulse laser beam is radiated on the predetermined cut line on the surface of the work under the conditions causing a multiple photon absorption and with a condensed point aligned to the inside of the work, and a modified area is formed inside the work along the predetermined determined cut line by moving the condensed point along the predetermined cut line, whereby the work can be cut with a rather small force by cracking the work along the predetermined cut line starting from the modified area and, because the pulse laser beam radiated is not almost absorbed onto the surface of the work, the surface is not fused even if the modified area is formed.
US08283593B2 Wire cleaning guide
A wire cleaning guide for guiding a wire in a feed direction and to clean the wire, including a gas supply nozzle for supplying plasma generating gas, a plasma generating chamber with plasma generating gas supplied from the gas supply nozzle thereto for transforming the plasma generating gas into plasma by energizing a bonding wire that passes there through to clean the wire by means of the plasma gas, and wire-feeder-side and bonding-tool-side guide holes for guiding the wire in the feed direction, the diameter of the wire-feeder-side guide hole is greater than that of the bonding-tool-side guide hole so that the outflow rate of gas after wire cleaning flowing between the wire-feeder-side guide hole and the wire is greater than that of gas after wire cleaning flowing between the bonding-tool-side guide hole and the wire.
US08283588B2 Method and system for sorting postal mail
A process is provided for analyzing the physical characteristics of flat articles being sorted to determine which downstream operations the articles should be processed with next. Length, height, width and stiffness information are received from sensors, and the data is analyzed to determine if the mail piece is automation compatible, extended capability or manual letter, or a flat.
US08283582B2 Deflection web for a keypad assembly
A deflection web is provided for use in a keypad assembly. The deflection web comprises a plurality of actuators resiliently coupled together by a flexible membrane. Each actuator of the deflection web corresponds to a key of the keypad assembly, and for each actuator, the flexible membrane comprises a corresponding radially outwardly extending flange whose thickness varies in a direction from the corresponding actuator. In some instances, the thickness of the flange may increase as the flange extends a distance radially outward from its corresponding actuator. A method for creating the deflection web of the keypad assembly and a method for assembling the keypad assembly are also provided.
US08283581B2 Integral keyboard assembly
An integral keyboard assembly is provided. The integral keyboard assembly includes a top casing, a keyboard module, and a support plate. The first surface of the top casing is defined a keyboard bonding area where a plurality of openings is arranged as a keyboard structure distribution. The keyboard module includes multiple keys with interspaces formed therebetween. Each of the keys is inserted into a corresponding one of the openings. The support plate is coupled to the top casing so that the keyboard module is sandwiched between the top casing and the support plate. By implementing the present invention, the keyboard assembly has better integrity and space impression. Furthermore, the keyboard module is provided with improved support by utilizing the support plate.
US08283576B2 Hinges for control box enclosure
A control box arrangement including at least one control box, the inside of which is sub-divided, or can be sub-divided, into a plurality of compartments which are arranged one above the other and can be closed in a sealing manner by associated doors with a peripheral sealing arrangement acting on the inside of the doors. The doors are connected, by one of the vertical sides thereof, to a frame of the control box in question by hinges in an articulated manner, and can be closed by a closing mechanism on the opposite vertical side. A first hinge section is fixed to a vertical section of the frame by a fixing section, and the door is mounted on an articulated section of the first hinge section in an articulated manner by a second hinge section applied thereto. A variable structural division of the inside of the control box and a corresponding arrangement of the doors is enabled if, in the closed state, the fixing section is arranged inside the peripheral sealing arrangement, while the articulated section is arranged outside the sealing arrangement.
US08283570B2 Semiconductor assembly and multilayer wiring board
A semiconductor assembly includes a multilayer wiring board including at least three insulating layers, first, second and third insulating layers and a semiconductor device attached to one principal surface of the first insulating layer. The first, second and third insulating layers are stacked in this order. The multilayer wiring board further includes a heat-insulating member made of a material having a lower thermal conductivity than the insulating layers. The heat-insulating member is disposed between the first and second insulating layers or next to the first insulating layer at a side opposite to the one principal surface.
US08283569B2 Electrode array and method of fabrication
An electrode array, having application as a cochlear implant, includes a tube formed of Parylene defining a hollow channel. A substrate formed primarily of Parylene is supported by the tube. In turn, a plurality of metallic electrodes and feed lines are supported by the substrate. Numerous voids are defined by the tube which opens into the hollow channel. The size and spacing of the voids regulate stiffness and curl of the tube to provide excellent fit within the cochlea.
US08283567B2 Flexible printed circuit board and touch screen panel apparatus having the same
A flexible printed circuit board (FPCB) simultaneously coupled to both surfaces of a substrate structure, e.g., a touch screen panel is provided. The FPCB includes a main substrate unit having a first pad unit and an auxiliary substrate unit extending from the main substrate unit to one side of the first pad unit. The auxiliary substrate unit includes a first substrate unit positioned parallel with the first pad unit along a first direction, a second substrate unit including a second pad unit, the second substrate unit spaced apart from the first substrate unit in a second direction, orthogonal to the first direction, and a plurality of third substrate units extending along the second direction between the first and second substrate units.
US08283566B2 Printed circuit boards by massive parallel assembly
A method of forming an interconnect substrate includes providing at least two unit cells, arranging the unit cells to form a desired circuit pattern, and joining the unit cells to form the interconnect substrate having the desired circuit pattern. A circuit substrate, has a desired circuit pattern on a substrate, the substrate made up of at least two unit cells having conductive lines electrically connected together.
US08283565B2 Flexible substrate
According to an aspect of an embodiment, a flexible circuit board for connecting a first device and a second device, the flexible circuit board comprises: a base material comprising a flexible material having a first end adapted to connect with the first apparatus, a second end adapted to connect with the second apparatus and a hollow arranged between the first end and the second end; a signal line arranged on a surface of the base material, the signal line capable of electrically connecting the first apparatus and the second apparatus, the signal line having a constant characteristic impedance along the signal line in association with the base material; and a line arranged on the base material and over the hollow, the line capable of electrically connecting the first apparatus and the second apparatus.
US08283558B2 Solar cell assembly with combined handle substrate and bypass diode and method
A solar cell assembly and method are disclosed. The solar cell assembly comprises a substrate having a front surface and a back surface, wherein the substrate has a p-n junction providing reverse bias protection, and wherein the substrate functions as a bypass diode. The solar cell assembly further comprises a multijunction solar cell having a plurality of solar cell layers, wherein the multijunction solar cell has a first surface and a second surface, the first surface being attached to the front surface of the substrate. The solar cell assembly further comprises an electrical connector element positioned adjacent the front surface of the substrate and the first surface of the multijunction solar cell, a first contact coupled to the back surface of the substrate, and at least one second contact coupled to a portion of the second surface of the multijunction solar cell.
US08283557B2 Heterojunction solar cell based on epitaxial crystalline-silicon thin film on metallurgical silicon substrate design
One embodiment of the present invention provides a heterojunction solar cell. The solar cell includes a metallurgical-grade Si (MG-Si) substrate, a layer of heavily doped crystalline-Si situated above the MG-Si substrate, a layer of lightly doped crystalline-Si situated above the heavily doped crystalline-Si layer, a backside ohmic-contact layer situated on the backside of the MG-Si substrate, a passivation layer situated above the heavily doped crystalline-Si layer, a layer of heavily doped amorphous Si (a-Si) situated above the passivation layer, a layer of transparent-conducting-oxide (TCO) situated above the heavily doped a-Si layer, and a front ohmic-contact electrode situated above the TCO layer.
US08283556B2 Nanowire-based device and array with coaxial electrodes
A nanowire-based photonic device and an array employ nanowires connecting between coaxially arranged electrodes in a non-uniform manner along a vertical extent of the electrodes. The device includes a pair of the electrodes separated by a circumferential gap. The nanowires chaotically emanate from an inner electrode of the pair and connect across the circumferential gap to an outer electrode of the pair. The array includes an outer electrode having an interconnected pattern of cells and inner electrodes, one per cell, arranged coaxially with and separated from the outer electrode by respective circumferential gaps. The nanowires chaotically emanate from the inner electrodes and connect across the respective circumferential gaps of the cells to the outer electrode. The device and the arrays further include a semiconductor junction between the electrodes.
US08283552B2 Docking system for pickups on electric guitars
A module for removable insertion into a stringed instrument body, the body having a transverse cavity extending from a lateral edge. A first fixation device is attached to the body in the cavity and having electrically conductive contact members. The module includes a base configured to engage the cavity as the module travels along an axis of movement into the cavity. The pickup module assembly having a base slidably inserted into the cavity along an axis from the lateral edge between removed and inserted positions. A plurality of pickups are carried by the base in operative proximity to the strings. A second fixation device is attached to the base and positioned to slideably engage the first fixation device when the base is in the inserted position. First and second electrical connectors are electrically coupled to the plurality of pickups and connected to the second fixation device. The first and second electrical connectors are positioned to sequentially engage the first and second contact members when the base is moved toward the inserted position. The first or second electrical connector being a détente that engage the first fixation device and releaseably engage the first fixation device to limit lateral movement of the base away from the inserted position.
US08283548B2 Method for recognizing note patterns in pieces of music
Method for recognizing similarly recurring patterns of notes in a piece of music containing note sequences distributed among parallel channels, the method having the steps of: a) repeatedly segmenting each channel and, for each type of segmentation, determining segments which are similar to one another and storing the latter in lists of candidate patterns with the respective entities thereof; b) calculating an intrinsic similarity value for each list; c) calculating coincidence values for each list for each channel with respect to the lists for all other channels; and d) combining the intrinsic similarity and coincidence values for each list to form a total value for each list, and using the pattern candidates in the lists with the highest total value in each channel as recognized note patterns in the channel.
US08283547B2 Scheme for providing audio effects for a musical instrument and for controlling images with same
A method for use with a musical instrument includes receiving a signal representative of a sound produced by the musical instrument, receiving a selection of an audio effect from a wireless controller, applying the audio effect to the signal representative of a sound produced by the musical instrument, and providing an output signal representative of the audio effect applied to the sound produced by the musical instrument. Other methods include causing an image to be responsive to a signal representative of motions of the musical instrument, and causing an image to be responsive to a signal representative of sound produced by the musical instrument. A computer readable storage medium may store a computer program adapted to cause a processor based system to execute the steps of any one or more of these methods.
US08283544B2 Automatic drum tuner
Methods and systems for automatically tuning a drum are disclosed. In some embodiments, the methods and systems include the following: (a) exciting a drum head to cause it to resonate; (b) sensing a vibration frequency at one or more points relative to each tension rod; (c) determining a global average vibration frequency of the vibration frequencies for the points relative to each tension rod; (d) comparing the vibration frequencies of each of the points relative to each tension rod to the global average vibration frequency to determine a correction value for each point relative to the global average vibration frequency; (e) automatically turning each tension rod based on the correction value for the relative points; (f) automatically repeating steps (a)-(e) until each of the vibration frequencies of each of the points relative to each tension rod is substantially similar; and (g) automatically turning each tension rod in a uniform direction substantially simultaneously.
US08283543B2 Bass drum support system
A bass drum support hoop for supporting one or more percussive instruments, and a method of supporting one or more percussive instruments, above a bass drum. The hoop comprising: an inward face, an outward face, a front edge, and a drum head edge adapted to engage a drum head; the hoop adapted to receive a plurality of tensioners opposite the drum head edge and at least one percussive instrument support for mounting at least one percussive instrument; the hoop capable of supporting the at least one percussion instrument above the outward face; whereby when the hoop is tensioned by the tensioners attached to a bass drum shell to apply pressure to the drum head positioned across the bass drum shell and in contact with the drum head edge, the hoop is capable of supporting the at least one percussive instrument support, and the at least one percussive instrument mounted on the support and positioned above the outward face of the hoop, while maintaining substantially uniform axial pressure against the drum head and not applying substantial radial pressure against the drum shell.
US08283542B2 Ajustable bridge for a stringed instrument
The present invention provides a reliable, easily adjustable bridge for a string instrument and preferably a guitar and even more preferably a six-string electric guitar. The adjustable bridge of the present invention allows for adjustment of string length using only four intonation adjustment screws.
US08283541B2 Ligature for woodwind instruments
A ligature is provided for use in a mouthpiece system for attaching a reed to a mouthpiece of a woodwind musical instrument. The ligature is constructed from overlapping layers of flexible strap to define pockets holding rigid bars. The ligature ends and rigid bars are brought together to form a loop that is placed over the mouthpiece and reed. A threaded closure mechanism is used to tighten the ligature around the mouthpiece. Within the interior of the loop, a rigid, weighted cradle is attached to the flexible strap by rivets. The cradle contains a plurality of identical cradle members stacked together in a laminated manner.
US08283539B2 Musical instrument string with hyper elliptical wound cover wire
A musical instrument string with hyper elliptical wound cover wire includes a wound musical string assembly (10) having a center string (12) and a shaped cover wire (24) wrapped in a spiral winding pattern (18). The shaped cover wire (24) is shaped to have a wire height (30) which is greater than a wire width (32) and is wound such that the wire height (30) is aligned perpendicularly to the longitudinal axis (14) of the center string (12) while the wire sides (26) abut tightly against those of adjacent iterations (20). The shaped cover wire (24) is shaped during the winding process by passing between pinch rollers (38) while under extrusion pressure.
US08283535B1 Inbred rice line 103006
An inbred rice line designated 103006 is disclosed. The invention relates to the seeds of inbred rice line 103006, to the plants of rice line 103006 and to methods for producing a rice plant by crossing line 103006 with itself or another rice line. The invention further relates to hybrid rice seeds and plants produced by crossing inbred rice line 103006 with another rice line.
US08283534B2 Plants and seeds of hybrid corn variety CH565013
According to the invention, there is provided seed and plants of the hybrid corn variety designated CH565013. The invention thus relates to the plants, seeds and tissue cultures of the variety CH565013, and to methods for producing a corn plant produced by crossing a corn plant of variety CH565013 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH565013.
US08283533B2 Cotton variety 09R573B2R2
The invention relates to the novel cotton variety designated 09R573B2R2. Provided by the invention are the seeds, plants, plant parts and derivatives of the cotton variety 09R573B2R2. Also provided by the invention are tissue cultures of the cotton variety 09R573B2R2 and the plants regenerated therefrom. Still further provided by the invention are methods for producing cotton plants by crossing the cotton variety 09R573B2R2 with itself or another cotton variety and plants produced by such methods.
US08283528B1 Soybean variety XB45Y10
A novel soybean variety, designated XB45Y10 is provided. Also provided are the seeds of soybean variety XB45Y10, cells from soybean variety XB45Y10, plants of soybean XB45Y10, and plant parts of soybean variety XB45Y10. Methods provided include producing a soybean plant by crossing soybean variety XB45Y10 with another soybean plant, methods for introgressing a transgenic, mutant trait, and/or native trait into soybean variety XB45Y10, methods for producing other soybean varieties or plant parts derived from soybean variety XB45Y10. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB45Y10 are further provided.
US08283527B2 Soybean variety XB02U10
A novel soybean variety, designated XB02U10 is provided. Also provided are the seeds of soybean variety XB02U10, cells from soybean variety XB02U10, plants of soybean XB02U10, and plant parts of soybean variety XB02U10. Methods provided include producing a soybean plant by crossing soybean variety XB02U10 with another soybean plant, methods for introgressing a transgenic, mutant trait, and/or native trait into soybean variety XB02U10, methods for producing other soybean varieties or plant parts derived from soybean variety XB02U10. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB02U10 are further provided.
US08283517B2 Transgenic mouse models of Aβ overexpression
A transgenic non-human animal, in particular a transgenic mouse encoding Aβ peptide proteins, which have been implicated in Aβ peptide-related diseases. Cells and cell lines comprising transgenes encoding for Aβ peptide. Methods and compositions for evaluating agents that affect Aβ peptide, for use in compositions for the treatment of Aβ peptide-related diseases.
US08283510B2 Process and apparatus for para-xylene production
A process of producing PX comprising providing a C8+ feedstock, the C8+ feedstock has C8 hydrocarbons and C9+ hydrocarbons, to a crystallization unit under crystallization conditions to produce a PX enriched stream having a PX concentration of at least 99.5 wt % based on the weight of the PX enriched stream, wherein the C8+ feedstock has a PX concentration of at least 70 wt % based on total weight of xylenes in the C8+ feedstock, which the C8+ feedstock having a C9+ hydrocarbons concentration in a range from 1 wppm to 10 wt % based on the total weight of the C8+ feedstock.
US08283509B2 Thermal-separation process with absorption heat pump
The invention comprises an absorption heat pump to supply energy to a distillation process or an outside process. The streams used to effect the absorption heat pump are to be combined in any case as a feedstream to a conversion process, and energy thus is conserved by avoiding the necessity of reseparating the streams.
US08283508B2 Method for producing aromatic compound
The present invention is a method for producing an aromatic compound by substituting the sulfonic acid group in a sulfonic acid aromatic-ester with a hydrogen atom in the presence of a platinum group metal catalyst, wherein an alkali metal carboxylate and/or an ammonium formate are made to coexist in the system. According to the present invention, an aromatic compound where the sulfonic acid group in a sulfonic acid aromatic-ester is substituted with a hydrogen atom, can be produced efficiently with good operability without using metal magnesium.
US08283507B2 Water gas shift for acetylene converter feed CO control
A process and apparatus are presented for the removal of carbon monoxide from ethylene streams. The removal of carbon monoxide before selective hydrogenation protects the catalyst in the selective hydrogenation reactor. Carbon monoxide levels are controlled with the water gas shift process to convert the carbon monoxide to carbon dioxide, with the carbon dioxide removed in an acid gas removal process.
US08283506B2 Production of fuel from renewable feedstocks using a finishing reactor
A process has been developed for producing fuel from renewable feedstocks such as plant and animal oils and greases. The process involves treating a first portion of a renewable feedstock by hydrogenating and deoxygenating in a first reaction zone and a second portion of a renewable feedstock by hydrogenating and deoxygenating in a second reaction zone and treating the effluents in a finishing reaction zone to provide a diesel boiling point range fuel hydrocarbon product. If desired, the hydrocarbon product can be isomerized to improve cold flow properties. A portion of the hydrocarbon product is recycled to the first reaction zone to increase the hydrogen solubility of the reaction mixture.
US08283504B2 Process for producing 2-propanol
The invention provides processes for producing 2-propanol with higher purity than heretofore possible while suppressing the by-production of impurities.A process of the invention produces 2-propanol by reacting acetone with hydrogen in the presence of a hydrogenation catalyst, wherein the process includes reacting a raw material mixture containing water and acetone, with hydrogen in the presence of a hydrogenation catalyst, and the raw material mixture contains water at 1.2 to 4.0 wt % based on 100 wt % of the total of the water and the acetone.
US08283500B2 Separation/purification of desflurane from hydrogen fluoride
An azeotrope comprising desflurane (CF3CFHOCF2H) and hydrogen fluoride (HF). The azeotrope can be prepared by fractionally distilling a crude mixture of desflurane and HF. Purer desflurane can be readily and easily separated from the azeotrope. It is emphasized that this abstract is provided to comply with the rules requiring an abstract which will allow a searcher or other reader quickly to ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the appended issued claims.
US08283499B2 Preparation of naphthoquinone compounds using 2,3-dihalonaphthoquinone
The present invention relates the use of 2,3-dihalonaphthoquinone compounds of Formula I wherein R1 and R2 are leaving groups like halogens selected from the group comprising Cl, Br, I and F and the R1 and R2 may be the same halogen or may contain different halogen groups, or sulphonyl groups, for making napthoquinone compounds of Formula IA wherein X is any aryl, heteroaryl, alkyl, cyclohexyl, substituted cylohexyl groups and the like.
US08283498B2 Oxidative desulfurization using a titanium(IV) catalyst and organohydroperoxides
Oxidative desulfurization (ODS) is an attractive alternative to hydrodesulfurization (HDS) technology due to its lower energy requirement for the removal of refractory sulfur species, such as dibenzothiophene (DBT), from heavier petroleum streams. Diesel containing DBT may be oxidized using a heterogeneous titanium(IV) catalyst and organohydroperoxide oxidant, such as tert-butyl hydroperoxide (TBHP), cumyl hydroperoxide (CHP) and/or ethylbenzene hydroperoxide (EBHP), which proves effective for the selective oxidation and removal of refractory sulfur compounds from diesel fuel.
US08283496B2 Aminoalkyl vinyl ethers comprising ethylenimine units, processes for their preparation and their use
Aminoalkyl vinyl ethers comprising alkylenimine units and of the formula H2C═CH—O—X—NH—[Al—]n—H  (I), in which [Al—]n is a linear or branched oligoalkylenimine chain having n alkylenimine units, n is a number of at least 1 and X is a straight-chain or branched C2- to C6-alkylene group, and salts of the monomers I with mineral acids or organic acids and quaternization products of the monomers I with alkyl halides or dialkyl sulfates, processes for the preparation of the compounds of the formula I by addition reaction of alkylenimines with amino-C2- to C6-alkyl vinyl ethers and use of the aminoalkyl vinyl ethers comprising alkylenimine units and of the formula I as monomers for the preparation of polymers for use in the paper industry, as antimicrobial coating materials, in detergents and for the treatment of metal surfaces.
US08283494B2 Process for the preparation of urea
Process for the preparation of urea from ammonia and carbon dioxide in a urea production process comprising, in a high-pressure synthesis section: a. a reactor, wherein ammonia and carbon dioxide react to form a urea-comprising synthesis solution; b. a stripper, wherein the urea-comprising synthesis solution is heated and stripped, optionally in counter-current with a stripping agent; c. a submerged condenser, wherein the gas leaving the top of the stripper is, at least partially, condensed to form a condensate solution and d. an ejector, in the line connecting the submerged condenser and the reactor, supporting the transport of the condensate solution from the submerged condenser to the reactor, wherein a gas stream leaving the top of the submerged condenser is controlled by one or more controlling elements.
US08283493B2 Process for the production of acetic acid
Process for the production of acetic acid by (a) introducing methanol, methyl acetate, dimethyl ether and/or methyl iodide and carbon monoxide into a first reaction zone containing a liquid reaction composition comprising a carbonylation catalyst, optionally a carbonylation catalyst promoter, methyl iodide, methyl acetate, acetic acid and water, (b) withdrawing at least a portion of the liquid reaction composition together with dissolved and/or entrained carbon monoxide and other gases from the first reaction zone, (c) passing at least a portion of the withdrawn liquid reaction composition to a second reaction zone, wherein at least a portion of the dissolved and/or entrained carbon monoxide is consumed, (d) passing at least a portion of the liquid reaction composition from the second reaction zone into a flash separation zone to form a vapor fraction, which comprises acetic acid, methyl iodide, methyl acetate and low pressure off-gas, comprising carbon monoxide; and a liquid fraction, which comprises carbonylation catalyst and optional carbonylation catalyst promoter, and (e) passing the vapor fraction from the flash separation zone to one or more distillation zones to recover acetic acid product. The temperature of the liquid reaction composition withdrawn from the first reaction zone is in the range of 170 to 195° C.; and the temperature of the liquid reaction composition passed from the second reaction zone to the flash separation zone is at least 8° C. greater than the temperature of the liquid reaction composition withdrawn from the first reaction zone.
US08283490B2 Process for the carbonylation of dimethyl ether
Process for the production of methyl acetate by carbonylating a dimethyl ether feed with carbon monoxide in the presence of hydrogen under substantially anhydrous conditions, at a temperature in the range of greater than 250° C. to 350° C. and in the presence of a zeolite catalyst effective for said carbonylation. The concentration of dimethyl ether is at least 1 mol % based on the total feed.
US08283483B2 Triglyceride macromonomers
A polymerisable ethylenically unsaturated macromonomer being the reaction product of: i) an adduct formed from the reaction of an unsaturated non-mineral oil reacted with an enophile having an acid, ester or anhydride moiety and ii) an ethylenically unsaturated monomer having a moiety reactive with the acid, ester or anhydride moiety of the enophile and iii) a chain extender material having at least two moieties reactive with the acid, ester or anhydride moiety of the enophile.
US08283482B2 Method for producing cross-coupling compound
To provide a method for performing a cross-coupling reaction of a Grignard compound with an alkyl halide simply, efficiently and in high yield, a method for obtaining a ω-bromo long chain carboxylic acid simply and efficiently using an easily obtainable raw material and a method for producing a useful branched fatty acid simply and efficiently [R1: an alkyl group having 1 to 15 carbon atoms, R2: an alkyl group having 1 to 30 carbon atoms with a carboxyl group and X and X′: a halogen atom] [n: an integer of 9 to 17] [n: an integer of 9 to 17, R1a: a branched alkyl group having 3 to 8 carbon atoms and X: a halogen atom].
US08283477B2 Method for preparing N-substituted maleimides
The present invention relates to a method of preparing N-substituted maleimide in high purity and high yield, wherein, unlike a conventional method of preparing N-substituted maleimide after preparing N-substituted maleamic acid, an organic solvent, an acid catalyst, a dehydration co-catalyst and a stabilizer are added into a reactor without separately preparing N-substituted maleamic acid, and then a primary amine is added into the reactor to form an amine salt, maleic anhydride is added into the reactor, and the resulting mixture is subjected to a dehydration-cyclization reaction, wherein water produced during the reaction is azeotropically distilled with the organic solvent so as to effectively suppress formation of a maleimide polymer. Particularly, the invention simplifies the process, has high yield, minimizes side reactions, eliminates the introduction of expensive raw materials and the complicated treatment of the reaction solution and significantly shortens the time over which the raw materials and maleic anhydride are added.
US08283474B2 Azabicyclo (3.1.0) hexane derivatives useful as modulators of dopamine D3 receptors
The present invention relates to novel compounds of formula (I) or a pharmaceutically acceptable salt thereof: wherein G is selected from a group consisting of: phenyl, pyridyl, benzothiazolyl, indazolyl; p is an integer ranging from 0 to 5; R1 is independently selected from a group consisting of: halogen, hydroxy, cyano, C1-4alkyl, haloC1-4alkyl, C1-4alkoxy, haloC1-4alkoxy, C1-4alkanoyl; or corresponds to a group R5; R2 is hydrogen or C1-4alkyl; R3 is C1-4alkyl; R4 is hydrogen, or a phenyl group, a heterocyclyl group, a 5- or 6-membered heteroaromatic group, or a 8- to 11-membered bicyclic group, any of which groups is optionally substituted by 1, 2, 3 or 4 substituents selected from the group consisting of: halogen, cyano, C1-4alkyl, haloC1-4alkyl, C1-4alkoxy, C1-4alkanoyl; R5 is a moiety selected from the group consisting of: isoxazolyl, —CH2—N-pyrrolyl, 1,1-dioxido-2-isothiazolidinyl, thienyl, thiazolyl, pyridyl, 2-pyrrolidinonyl, and such a group is optionally substituted by one or two substituents selected from: halogen, cyano, C1-4alkyl, haloC1-4alkyl, C1-4alkoxy, C1-4alkanoyl; and when R1 is chlorine and p is 1, such R1 is not present in the ortho position with respect to the linking bond to the rest of the molecule; and when R1 corresponds to R5, p is 1; processes for their preparation, intermediates used in these processes, pharmaceutical compositions containing them and their use in therapy, as modulators of dopamine D3 receptors, e.g. to treat drug dependency or as antipsychotic agents.
US08283472B2 Synthesis of methylphenidate and analogs thereof
A synthetic process for the preparation of amino acid esters such as methylphenidate and analogs thereof is disclosed. The process involves reacting an amino acid such as α-phenyl-α-(2-piperidinyl)acetic acid or an analog thereof with an alcohol such as methanol in the presence of an acid and a water sequestrant such as trimethyl orthoacetate. In some embodiments, the water sequestrant is added to the reaction mixture after an initial period of esterification and then the reaction is allowed to continue. The α-phenyl-α-(2-piperidinyl)acetic acid methyl ester or analog thereof is then isolated from the reaction mixture. In one variation of the process, the supernatant liquid may be recycled in subsequent runs to increase yield and product purity.
US08283470B2 Method for the preparation of solifenacin and intermediate thereof
A method for the preparation of solifenacin by reacting quinuclidin-3-ol and bis (aryl) carbonate to form (3R)-1-azabicyclo[2.2.2]oct-3-yl 4-aryl carbonate of formula (IVa); and treating (3R)-1-azabicyclo[2.2.2]oct-3-yl 4-aryl carbonate of formula (IVa) with (1S)-1-phenyl- 1,2,3,4-tetrahydroisoquinoline of formula (V) in an inert atmosphere to form a Solifenacin base, which is converted into its pharmaceutically acceptable salts. The invention also provides a compound, (3R)-1-azabicyclo[2.2.2]oct-3-yl 4-aryl carbonate of formula (IVa), which is used as an intermediate for the preparation of Solifenacin base and a process for the preparation thereof.
US08283469B2 Perylene diimide derivative and organic semiconductor element using the same material
The present invention discloses a soluble and air-stable perylene diimide (PDI) derivative to function as an N-type organic semiconductor material. In the PDI derivative of the present invention, the core thereof is substituted by electron withdrawing groups, and the side chains thereof are substituted by benzene functional groups, whereby are promoted the solubility and air-stability of the molecule. The PDI derivative of the present invention can be used to fabricate an organic semiconductor element via a soluble process at a low temperature and under an atmospheric environment.
US08283468B2 Organometallic complex and method for producing the same
An organometallic complex [Cu2(pyridine-3,5-dicarboxylate)2]n is provided by bonding a plurality of Cu2(pyridine-3,5-dicarboxylate)2 repeating units to each other. The organometallic complex can be obtained by the steps of dissolving copper acetate monohydrate or anhydrate and pyridine-3,5-dicarboxylic acid in a solvent, heating the solution at 50° C. to 140° C. for 24 to 168 hours to generate a reaction product, and then removing a guest molecule from the reaction product.
US08283467B2 Synthesis of boronic ester and acid compounds
The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.
US08283466B2 Catalytic deamination for caprolactam production
Catalytic processes for preparing caprolactam, pipecolinic acid, and their derivatives, from lysine or alpha-amino-epsilon-caprolactam starting materials, and products produced thereby. A process for preparing caprolactam or a derivative thereof, the process comprising contacting a reactant comprising lysine or alpha aminocaprolactam with a catalyst and a gas comprising hydrogen gas, in the presence of a solvent. The catalyst may be provided on a support material, such as a transition metal.
US08283461B2 Multiple promoter expression cassettes for simultaneous delivery of RNAi agents
The present invention provides multiple-promoter expression cassettes for simultaneous delivery of RNAi, preferably to mammalian cells in vivo.
US08283456B2 Triterpene saponins, methods of synthesis, and uses thereof
The present invention relates to triterpene glycoside saponin-derived adjuvants, syntheses thereof, intermediates thereto, and uses thereof. QS-7 is a potent immuno-adjuvant that is significantly less toxic than QS-21, a related saponin that is currently the favored adjuvant in anticancer and antiviral vaccines. Tedious isolation and purification protocols have hindered the clinical development of QS-7. A novel semi-synthetic method is provided wherein a hydrolyzed prosapogenin mixture is used to synthesize QS-7, QS-21, and related analogs, greatly facilitating access to QS-7 and QS-21 analogs for preclinical and clinical evaluation.
US08283455B2 Reagent compounds and methods of making same
The present invention describes novel compounds and methods for capping reactive groups on support and during multistep synthesis. These new capping reagents are also useful for high quality synthesis on solid supports and surfaces used as microarrays, biosensors, or in general as biochips. The compounds are also useful for controlling surface density of reactive groups on a support. The compounds may also be used to modify the hydrophilic/hydrophobic characteristics of a surface or a molecule. The compounds have functional utility in various applications in the fields of genomics, proteomics, diagnostics and medicine.
US08283454B2 Processes for the preparation of SGLT2 inhibitors
Provided are processes for the preparation of complexes that are useful in purifying compounds having an inhibitory effect on sodium-dependent glucose cotransporter SGLT. The processes can reduce the number of steps needed to obtain the target compounds and the complexes formed in the processes are typically provided in a crystalline form.
US08283452B2 Assay for the separation and quantification of hemagglutinin antigens
Described are methods for separating hemagglutinin (HA) antigens, comprising the steps of applying a reduced and derivatized antigen preparation comprising solubilized HA antigens and a detergent in a pH controlled solution, on a Reversed-Phase High-Performance Liquid Chromatography (RP-HPLC) column; and eluting the HA antigens from the column with an ion pairing agent in an organic mobile phase. The invention further relates to quantifying methods using the methods for separating the antigens with the further step of measuring the peak area of the eluted antigen in a chromatogram resulting from the elution step.
US08283451B2 Kit for prediction of pre-eclampsia
The present invention relates to a method of predicting pre-eclampsia (PE). The present invention also relates to a diagnostic kit for performing a method of predicting PE. In particular, the method determining the level of two or more markers selected from placenta growth factor (PlGF), plasminogen activator inhibitor-1 (PAI-1), plasminogen activator inhibitor-2 (PAI-2) and leptin.
US08283448B2 Methods for treating viral infection using IL-28 and IL-29 cysteine mutants
IL-28A, IL-28B, IL-29, and certain mutants thereof have been shown to have antiviral activity on a spectrum of viral species. Of particular interest is the antiviral activity demonstrated on viruses that infect liver, such as hepatitis B virus and hepatitis C virus. In addition, IL-28A, IL-28B, IL-29, and mutants thereof do not exhibit some of the antiproliferative activity on hematopoietic cells that is observed with interferon treatment. Without the immunosuppressive effects accompanying interferon treatment, IL-28A, IL-28B, and IL-29 will be useful in treating immunocompromised patients for viral infections.
US08283447B2 Immunosuppressive polypeptides and nucleic acids
The invention provides immunosuppressive polypeptides and nucleic acids encoding such polypeptides. In one aspect, the invention provides mutant CTLA-4 polypeptides and nucleic acids encoding mutant CTLA-4 polypeptides. Compositions and methods for utilizing such polypeptides and nucleic acids are also provided.
US08283444B2 Non-viral delivery of compounds to mitochondria
A conjugate comprises: (a) a mitochondrial membrane-permeant peptide; (b) an active agent or compound of interest such as a detectable group or mitochondrial protein or peptide; and (c) a mitochondrial targeting sequence linking said mitochondrial membrane-permeant peptide and said active mitochondrial protein or peptide. The targeting sequence is one which is cleaved within the mitochondrial matrix, and not cleaved within the cellular cytoplasm, of a target cell into which said compound is delivered. Methods of use of such compounds are also described.
US08283443B2 Method for purifying protein
The present invention provides a method for purifying a protein, includes the step of: contacting a fusion protein of a first protein and a second protein with a bivalent cation-containing solution, the fusion protein being adsorbed to a silicon oxide-containing substance, the first protein being capable of binding to the silicon oxide-containing substance in a solution containing 0.1M sodium chloride. With this arrangement, it is possible to easily produce large quantity of proteins which are high in purity without sacrificing activity of the proteins.
US08283442B2 Antiviral compounds
The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
US08283439B2 Recombinant fragments and synthetic peptides of 17-kDa polypeptide useful in detecting Bartonella henselae
The present disclosure describes recombinant and synthetic polypeptides of Bartonella henselae and related methods and kits for the detection of antibodies specific for Bartonella henselae. The 17-kDa polypeptides, methods and kits are useful in the detection of recent and/or ongoing infections with Bartonella henselae, which can be useful in the diagnosis of Cat Scratch Disease (CSD).
US08283438B2 Functionalized polymers using protected thiols
A process for the preparation of functional molecules using the thiol-ene coupling reaction and a process for the preparation of protected functional thiols, specifically thioesters is provided. The methods may be used to make functional polymers and other molecules. The method of making a functionalized polymer using a thiol-ene reaction comprises: providing a functionalized thioester having the following formula: wherein R is a functional group and COR′ is a protecting group; cleaving the functionalized thioester, forming a functional thiol and an acyl group; providing a polymer having a pendant vinyl group; and reacting the polymer with the functional thiol whereby a functionalized polymer is formed, wherein the functional thiol is not isolated prior to reacting with the polymer.
US08283435B2 PHA adhesive compositions
PHA adhesive compositions, and related methods and articles are disclosed.
US08283432B2 Siloxane polymer containing tethered fluoroquinolone
A polymer that is a polysiloxane polymer has fluoroquinolone antibiotic groups, or pharmaceutically acceptable salts thereof, attached via linkers. The linkers may be hydrolytically labile thereby providing a manner of releasing the fluoroquinolone antibiotic from the polymer.
US08283430B2 Composition for manufacturing a carboxylic group-containing polymer and a polymer manufactured by using the same
The present invention relates to a composition for manufacturing a carboxylic group-containing polymer and a carboxylic group-containing polymer manufactured by using the same. More particularly, the present invention relates to a composition for manufacturing a carboxylic group-containing polymer comprising an allyl monomer having a long chain of a hydrophilic part containing alkylene oxide and a side chain of a hydrophobic part containing fatty acid ester as a dispersion promoter; a vinyl group-containing unsaturated carboxylic acid; a vinyl group-containing crosslinking agent; and a radical polymerization initiator, and a carboxylic group-containing polymer manufactured by using the same wherein the polymer can be dispersed in water without stirring, its dispersion solution has low viscosity, and its neutralized viscous solution obtained by alkali neutralization has high viscosity and transparency. Therefore, the carboxylic group-containing polymer of the present invention can be effectively used in the fields of a thickener and a dispersion stabilizer for an emulsion, a suspension and the like.
US08283426B2 Fibres and nonwoven prepared from polypropylene having a large dispersity index
The present invention relates to a process for the production of fibers and filaments with polypropylene having a broad polydispersity index. The present invention also relates to high elongation nonwoven prepared from such fibers and filaments. It further relates to films and laminates prepared from high elongation nonwoven.
US08283423B2 Polymer synthetic technique
The present invention generally relates to methods for the synthesis of species including monomers and polymers. Methods of the invention comprise the use of chemical techniques including metathesis chemistry to synthesize, for example, monomers and/or polymers with desired functional groups.
US08283421B2 Composition from a polyisocyanate and a polyether monoamine
Composition obtained by reacting a polyisocyanate which is a diphenylmethane diisocyanate, optionally comprising a homologue comprising 3 or more isocyanate groups, and/or a variant of such diisocyanate with a monoalkylether of a polyoxyalkylene monoamine having an average molecular weight of 550-3000 and an oxyethylene content of more than 50% by weight, calculated on the weight of the monoamine, and the alkyl group having 1-4 carbon atoms at index of 100-250. It is used as plasticizer, particularly in polyurethane and/or polyurea materials.
US08283420B2 Crosslinkable polyethylene composition, method of making the same, and articles made therefrom
The instant invention is a crosslinkable polyethylene composition obtained via a process comprising the steps of (1) providing a polyethylene component; (2) providing an organic peroxide crosslinking agent,(3) providing a crosslinking coagent which comprises at least two terminal carbon-carbon double bonds and is an alkadiene, alkatriene, or alkatetraene compound; (4) melt blending the polyethylene component, the crosslinking agent, and the crosslinking coagent at a temperature less than the decomposition temperature of the crosslinking agent; and (5) thereby forming the crosslinkable polyethylene composition. The crosslinkable polyethylene composition may further include a scorch inhibitor, a cure booster, a stable free radical, one or more conventional additives, and/or combinations thereof. The instant invention further includes articles comprising the crosslinked product of the crosslinkable polyethylene composition.
US08283419B2 Olefin functionalization by metathesis reaction
This invention relates to a process to functionalize propylene co-oligomer comprising contacting an alkene metathesis catalyst with a heteroatom containing alkene, and a propylene a co-oligomer having an Mn of 300 to 30,000 g/mol comprising 10 to 90 mol % propylene and 10 to 90 mol % of ethylene, wherein the oligomer has at least X % allyl chain ends, where: 1) X=(−0.94 (mol % ethylene incorporated)+100), when 10 to 60 mol % ethylene is present in the co-oligomer, and 2) X=45, when greater than 60 and less than 70 mol % ethylene is present in the co-oligomer, and 3) X=(1.83*(mol % ethylene incorporated)−83), when 70 to 90 mol % ethylene is present in the co-oligomer. This invention also relates to a process to functionalize propylene homo-oligomer comprising contacting an alkene metathesis catalyst with a heteroatom containing alkene, and a propylene homo-oligomer, comprising propylene, wherein the oligomer has: at least 93% allyl chain ends, an Mn of about 500 to about 20,000 g/mol, an isobutyl chain end to allylic vinyl group ratio of 0.8:1 to 1.2:1.0, and less than 100 ppm aluminum.
US08283415B2 Polyethylene and poly(hydroxyl carboxylic acid) blends
A resin composition comprising at least 0.1% by weight of poly(hydroxy carboxylic acid) and at least 50% by weight of polyethylene prepared with a single-site catalyst, preferably a metallocene.
US08283411B2 Plasticised polyvinyl chloride
Esters of cyclohexane polycarboxylic acids are used as plasticizers for polyvinyl chloride to enable products with comparable mechanical properties to be obtained using less polyvinyl chloride. Use of these esters also produces formulations with increased stability to ultra-violet light, improved low temperature properties, lower viscosity and improved processability as well as reduced smoke on burning. The esters of cyclohexane polycarboxylic acids may be used alone or in admixture with other plasticizers when the esters of cyclohexane polycarboxylic acids may act as viscosity depressants. Fast fusing plasticizers may also be included. The formulations are particularly useful in the production of a range of goods from semi-rigid to highly flexible materials and are particularly useful in the production of medical materials such as blood bags and tubing.
US08283408B2 Thermoplastic-toughened cyanate ester resin composites with low heat release properties
Composite materials that contain thermoplastic-toughened cyanate ester resins as the resin matrix. The composite materials exhibit low levels of heat release when burned. The matrix resins are composed of from 50 to 80 weight percent of a cyanate ester resin component. The matrix resin composition also includes from 10 to 40 weight percent of a thermoplastic blend that is composed of polyetherimide and polyamideimide. The epoxy resin composition further includes from 1 to 10 weight percent of a curative agent. The composite materials may be used for primary structures in aircraft and other load-bearing structures.
US08283406B2 Thermoplastic polymer and novolac composition and method
Compositions comprising a novolac polymer, an olefin-based polymer with an epoxy group, a filler and optionally a thermoplastic polymer are provided. The compositions may be halogen-free. The present compositions exhibit excellent compatibility between the novolac polymer and the olefin-based polymer with an epoxy group resulting in compositions with superior mechanical properties.
US08283403B2 Carbon nanotube-reinforced nanocomposites
Carbon nanotubes (CNTs) are so long that they cannot be penetrated inbetween carbon fibers during a prepreg preparation process, and are shortened in order for them not to be filtered out by the carbon fibers. This results in a huge improvement of the mechanical properties (flexural strength and flexural modulus) compared with neat epoxy.
US08283401B2 Conjugated diene polymer manufacturing method, polybutadiene, and rubber composition utilizing the same
Provided by using a catalyst containing an yttrium compound is conjugated diene polymer with very low solution viscosity, improved workability, high degree of branching, and high content of cis-1,4 structures. Also provided is a rubber composition utilizing the polymer and allowing excellent dispersion of reinforcing agent. According to a method of manufacturing a conjugated diene polymer characterized by polymerizing a conjugated diene at 50 to 120° C. in the presence of a catalyst obtained from (A) an yttrium compound, (B) an ionic compound consisting of a non-coordinating anion and a cation, and (C) an organoaluminum compound, the conjugated diene polymer has the following characteristics that: (1) a ratio (Tcp/ML1+4) between a 5 wt % toluene solution viscosity (Tcp) measured at 25° C. and a Mooney viscosity (ML1+4) at 100° C. is 0.1 to 1.2; and (2) a content of cis-1,4 structures is 80% or higher, and a content of 1,2 structures is lower than 5%.
US08283398B2 Polyhedral silsesquioxane modified polyimide containing intermediate transfer members
An intermediate transfer media that includes a single layer of a polyhedral silsesquioxane polyimide, and where the silsesquioxane is attached to the polyimide or a multi layer transfer media that includes a supporting substrate, such as a polyimide, and thereover a polyhedral silsesquioxane modified polyimide, and where the silsesquioxane is attached to the polyimide.
US08283396B2 Curable fluorine-containing polyether composition
Disclosed is a curable fluorine-containing polyether composition comprising (A) 100 parts by weight of a fluorine-containing polyether compound of the formula: wherein R1 is a hydrogen atom, a C1-C3 alkyl group, or a phenyl group, X is a bromine or iodine atom, l and m are integers of 10 or more, and l+m is 30 to 200; (B) 1 to 20 parts by weight of a fluorine-containing aromatic boronic acid ester compound of the formula: wherein R2 is a C2-C10 divalent aliphatic hydrocarbon group, and Y is a C1-C20 fluoroalkyl group; (C) 0.0001 to 1 parts by weight of a zero-valent or divalent organopalladium compound; (D) 0.5 to 10 parts by weight of a basic inorganic or organic compound; and (E) 0 to 5 parts by weight of an organophosphorus compound. The curable fluorine-containing polyether composition can produce a cured product that has improved compression set characteristics.
US08283393B2 Device for producing dispersions and method of producing dispersions
The instant invention is a device for producing dispersions and method of producing dispersions. The device for producing dispersions includes a first stator, a second stator, a shell encasing the first stator and the second stator, a rotor being disposed therebetween the first stator and the second stator thereby forming a first chamber and a second chamber, at least one first inlet port into the first chamber, and at least one outlet port out of the second chamber. The device may optionally include at least one additional second inlet port into the second chamber. The method of producing a polyurethane dispersion includes the following steps: (1) providing a device for producing a dispersion including a first stator, a second stator, a shell encasing the first stator and the second stator, a rotor being disposed therebetween the first stator and the second stator thereby forming a first chamber and a second chamber, at least one first inlet port into the first chamber, at least one outlet port out of the second chamber; and optionally one or more additional second inlet ports into the second chamber; (2) introducing a prepolymer phase and an aqueous phase into the first chamber via the first inlet ports; (3) emulsifying the prepolymer phase in the aqueous phase; (4) thereby producing a prepolymer emulsion; (5) introducing a chain extender agent into the emulsion in the second chamber via the second inlet port; (6) chain extending the prepolymer; and (7) thereby producing a polyurethane dispersion.
US08283387B2 Process for the conversion of synthesis gas to oxygenates
Process for converting carbon oxide(s) and hydrogen containing feedstocks to oxygen containing hydrocarbon compounds, in the presence of a particulate catalyst, by reacting carbon oxide(s) and hydrogen in the presence of a particulate catalyst in a conversion reactor to form products containing oxygen containing hydrocarbon compounds. Ether(s) selected from ethyl, propyl and butyl ether are added and reacted inside the conversion reactor.
US08283386B2 Method of operating a fluid bed reactor
Method of operating a three-phase slurry reactor includes feeding at a low level at least one gaseous reactant into a vertically extending slurry body of solid particles suspended in a suspension liquid, the slurry body being contained in at least two vertically extending shafts housed within a common reactor shell, each shaft being divided into a plurality of vertically extending channels at least some of which are in slurry flow communication and the slurry body being present in at least some of the channels. The gaseous reactant is allowed to react as it passes upwardly through the slurry body present in at least some of the channels of the shafts, thereby to form a non-gaseous and/or a gaseous product. Gaseous product, if present, and/or unreacted gaseous reactant is allowed to disengage from the slurry body in a head space above the slurry body.
US08283385B2 Reversibly switchable surfactants and methods of use thereof
Reversible switchable surfactants are provided. A surfactant is the salt of an amidine or guanidine: having at least one R group that is a hydrophobic moiety selected from the group consisting of higher aliphatic moiety, higher siloxyl moiety, higher aliphatic/siloxyl moiety, aliphatic/aryl moiety, siloxyl/aryl moiety, and aliphatic/siloxyl/aryl moiety. The other R groups are smaller moieties such as H, C1 to C4 aliphatic or the like. The surfactant is turned on by a gas that liberates hydrogen ions, such as, for example, carbon dioxide, which liberates hydrogen ions in the presence of water. The surfactant is turned off by exposure to a flushing gas and/or heating. When “on” the surfactants are useful to stabilize emulsions, and when “off” they are useful to separate immiscible liquids or a liquid and a solid. The surfactants find uses in polymerization and in the oil industry.
US08283383B2 Biphenyl amides as P2X3 and P2X2/3 antagonists
Compounds of the formula I: or a pharmaceutically acceptable salt thereof, wherein, R1 is optionally substituted phenyl or optionally substituted pyridinyl, and R2, R3, R4, R5, R6, R7, R8 and R9 are as defined herein. Also disclosed are methods of using the compounds for treating diseases associated with P2X3 and/or a P2X2/3 receptor antagonists and methods of making the compounds.
US08283382B2 Vitamin K for prevention and treatment of skin rash secondary to anti-EGFR therapy
The invention provides methods and compositions for treating and preventing a skin rash secondary to anti-epidermal growth factor receptor (EGFR) therapy, where the method comprises applying a vitamin K analog or a phosphatase inhibitor to the skin.
US08283378B2 Phenylurea inhibitors of the SOAT-1 enzyme and pharmaceutical/cosmetic compositions comprised thereof
Novel phenylurea compounds of formula (I): and cosmetic and pharmaceutical compositions containing same are useful for treating disorders of the sebaceous gland, e.g., acne, or have cosmetic applications.
US08283377B2 Method for inhibiting blood vessel stenosis
Provided is a method for inhibiting blood vessel stenosis in a subject, comprising administrating to the subject an effective amount of an active ingredient selected from a group consisting of a compound of formula (I), a pharmaceutically acceptable salt of the compound, a pharmaceutically acceptable ester of the compound, and combinations thereof. Also provided is a method for inhibiting blood vessel stenosis in a subject, comprising administration to the subject an effective amount of an Angelicae Sinensis extract comprising the compound of formula (I).
US08283369B2 Compounds and compositions and methods of use
Described herein are compounds useful in the modulation of blood uric acid levels, formulations containing them and methods of using them. In some embodiments, the compounds described herein are used in the treatment or prevention of disorders related to aberrant levels of uric acid.
US08283366B2 Derivatives of pyridoxine for inhibiting HIV integrase
The present invention relates to compounds of Formula I or pharmaceutically acceptable salts, solvates or formulations thereof. Compounds of Formula I inhibit HIV-integrase enzyme and are useful for preventing and treating of HIV infection, acquired immune deficiency syndrome (AIDS), AIDS-related complex (ARC), hepatitis C, and other diseases and conditions caused or mediated by HIV infection.
US08283365B2 Indole modulators of the alpha 7 nicotinic acetylcholine receptor
This invention relates to modulation of the α7 nicotinic acetylcholine receptor (nAChR) by a compound of formula (I) or a salt thereof
US08283364B2 Compounds which have activity at M1 receptor and their uses in medicine
Compounds of formula (I) and salts are provided: wherein R4 is fluoro, R5 is selected from hydrogen, halogen, cyano, C1-6alkyl, C1-6alkyl substituted with one or more fluorine atoms, C1-6alkoxy, and C1-6alkoxy substituted with one or more fluorine atoms; and R6 is selected from halogen, cyano, C1-6alkyl, C1-6alkyl substituted with one or more fluorine atoms, C3-6cycloalkyl, C3-6cycloalkyl substituted with one or more fluorine atoms, C1-6alkoxy and C1-6alkoxy substituted with one or more fluorine atoms, and Q is hydrogen or C1-6alkyl. The compounds are expected to be useful for therapy, for example in the treatment of psychotic disorders and cognitive impairment.
US08283356B2 2,4- Di(hetero)-arylamino-pyrimidine derivatives as ZAP-70 and/or SYK inhibitors
Disclosed are pyrimidine derivatives of formula wherein R0, R1, R3 to R9, and Z have a signification as indicated in claim 1, which have interesting pharmaceutical properties.
US08283355B2 Pyrimidine derivatives as POSH and POSH-AP inhibitors
Pyrimidine deriviatives are ubiquination inhibitors that inhibit the ubiquitin ligase activity, particularly of POSH polypeptides, are useful for the treatment of viral infections and neurological disorders.
US08283353B2 Fused ring compound and use thereof
Provided is a novel compound represented by the following formula Wherein each symbol is as defined in the specification, or a salt thereof, which has an angiotensin II receptor antagonistic activity and a peroxisome proliferator-activated receptor γ agonistic activity, and is useful as an agent for the prophylaxis or treatment of circulatory diseases such as hypertension and the like and/or metabolic diseases such as diabetes and the like, and the like.
US08283348B2 1-benzyl-3-hydroxymethylindazole derivatives and use thereof in the treatment of diseases based on the expression of MCP-1, CX3CR1 and p40
The present invention relates to novel 1-benzyl-3-hydroxymethylindazole derivatives according to formula (I) described in the claims, and to a pharmaceutical composition comprising them, together with a pharmaceutically acceptable vehicle. In addition, the present invention relates to the use of 1-benzyl-3-hydroxymethylindazole derivatives for the preparation of a pharmaceutical composition that is active in the treatment of diseases based on the expression of MCP-1, CX3CR1 and p40, and to their use in a method for treating or preventing diseases based on the expression of MCP-1, CX3CR1 and p40.
US08283345B2 Azetidine analogues of nucleosidase and phosphorylase inhibitors
Disclosed are azetidine analogues of nucleosidase and nucleoside phosphorylase inhibitors, the use of these compounds as pharmaceuticals, pharmaceutical compositions containing the compounds, methods of treating certain diseases using the compounds, processes for preparing the compounds, and intermediates useful in the preparation of the compounds.
US08283344B2 Method of treating inherited severe neutropenia
The invention is directed to a method of treating severe neutropenia, and in particular, cyclic neutropenia (CN) or severe congenital neutropenia (SCN), in a patient in need of such treatment comprising: administering a therapeutically effective amount of a compound of Formula (I) or a pharmaceutically acceptable salt thereof.
US08283342B2 Napadisylate salt of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one as agonist of the β2 adrenergic receptor
The present disclosure relates to crystalline monoapadisylate and/or heminapadisylate salt of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one, and pharmaceutically acceptable solvates thereof. The present disclosure also relates to pharmaceutical compositions comprising the crystalline monoapadisylate and/or heminapadisylate salt of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one, and to methods of treatment comprising these pharmaceutical compositions.
US08283341B2 Use as medicaments of derivatives of cholest-4-en-3-one, pharmaceutical compositions containing them, novel derivatives and their preparation process
A method for providing neuroprotection to a patient in need of neuroprotection, comprising administering a neuroprotective-effective amount of a compound of formula I in which X is an oxygen atom or an ═N—OH group, R is selected from the group consisting of A is a hydrogen atom or together with B a carbon-carbon bond, B is a hydrogen atom, a hydroxy group or together with A a carbon-carbon bond, C is a hydrogen atom or together with D a carbon-carbon bond, D is a hydrogen atom or together with C a carbon-carbon bond, E is a hydrogen atom or together with F a carbon-carbon bond, F is a hydrogen atom or together with E a carbon-carbon bond, or an addition salt with a pharmaceutically acceptable acid.
US08283339B2 Vinyl phosphonate lysophosphatidic acid receptor antagonists
The present invention provides LPA analogs that are antagonists at the LPA receptors.
US08283338B2 GIP secretion inhibitor
The present invention provides a postprandial GIP secretion inhibitor comprising potassium alginate as an active ingredient. The postprandial GIP secretion inhibitor of the present invention is useful as a medicine or a food product. The present invention also provides use of potassium alginate for the manufacture of a postprandial GIP secretion inhibitor. The present invention also provides a method for inhibiting postprandial GIP secretion, which comprises administering potassium alginate to a subject in need thereof or causing a subject in need thereof to consume potassium alginate.
US08283336B2 Unit dosage for brain health
The invention pertains to a composition comprising (i) uridine in nucleobase, nucleoside and/or nucleotide form; (ii) docosahexaenoic acid (DHA) and/or eicosapentaenoic acid (EPA); and (iii) a tocopherol and/or an equivalent thereof, wherein said composition has: a) a weight of 200-3000 mg per unit dose; b) an energy content of less than 50 kcal per unit dose; and/or c) a volume between 0.1 and 10 ml per unit dose. The invention also pertains to the use of such composition in reducing abeta plaque burden and neurodegeneration, in the treatment of diseases related with imparted nerve functioning, in particular dementia, Alzheimer's disease and memory disorders.
US08283333B2 Lipid formulations for nucleic acid delivery
The present invention provides novel, serum-stable lipid particles comprising one or more active agents or therapeutic agents, methods of making the lipid particles, and methods of delivering and/or administering the lipid particles. More particularly, the present invention provides serum-stable nucleic acid-lipid particles (SNALP) comprising a nucleic acid (e.g., one or more interfering RNA molecules), methods of making the SNALP, and methods of delivering and/or administering the SNALP (e.g., for the treatment of cancer). In particular embodiments, the present invention provides tumor-directed lipid particles that preferentially target solid tumors. The tumor-directed formulations of the present invention are capable of preferentially delivering a payload such as a nucleic acid to cells of solid tumors compared to non-cancerous cells.
US08283332B2 PFKFB4 inhibitors and methods of using the same
Methods of reducing expression of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) and methods of treating a cancer in a cell are provided, the methods including contacting a cell with an effective amount of a PFKFB4 inhibitor. Short hairpin RNA (shRNA) and small interfering RNA (siRNA) inhibitors of PFKFB4 and their methods of use are also provided.
US08283331B2 Methods to regulate miRNA processing by targeting Lin-28
The present invention relates generally to methods to regulate microRNA (miRNA) biogenesis, in particular the regulation of the processing of pri-miRNA to mature miRNA by Lin-28 and/or variants such as Lin28B. In particular, the present invention relates to methods and compositions comprising at least one agent which inhibits Lin-28 function or activity and/or expression to increase the processing of pri-mRNA to mature miRNA. More specifically, one aspect of the invention is directed to treating and/or preventing cancer in a subject by administering an agent that inhibits Lin-28 activity or expression to a subject, preferably a human subject.
US08283328B2 Immunostimulatory nucleic acids
The invention relates to a class of soft or semi-soft CpG immunostimulatory oligonucleotides that are useful for stimulating an immune response.
US08283327B2 Palatinose for enhancing dietary supplement and pharmaceutical delivery
The present invention is directed to a dietary supplement comprising palatinose or a derivative thereof. The dietary supplement may be a nutritional product, a sports performance product, a weight loss product or a meal replacement product. The present invention is also directed to a method of increasing the absorption of a compound into the bloodstream, cells and tissue comprising administering palatinose, or a derivative thereof, in combination with the compound. The present invention also relates to a diluent for parenteral compounds. The diluent comprises palatinose or a derivative thereof. Another aspect of the present invention is directed to a method of decreasing the recovery time to pre-performance levels of total adenosine triphosphate (ATP) levels in a mammal comprising administering palatinose, or a derivative thereof, to the mammal. The present invention is further directed to a method of supplying a compound to a diabetic patient, burn victim patient or trauma victim patient. The method comprises administering palatinose, or a derivative thereof, in combination with the compound.
US08283326B2 Crystalline form of 4-(beta-D-glucopyranos-1-yl)-1-methyl-2-[4-((S)-tetrahydrofuran-3-yloxy)-benzyl]-benzene, a method for its preparation and the use thereof for preparing medicaments
The invention relates to a crystalline form of 4-(β-D-glucopyranos-1-yl)-1-methyl-2-[4-((S)-tetrahydrofuran-3-yloxy)-benzyl]-benzene, to a method for the preparation thereof, as well as to the use thereof for preparing medicaments.
US08283325B2 Virus scaffold for self-assembled, flexible and light lithium battery
A variety of compositions that include a metal oxide, films and batteries comprising one or more of the compositions, and methods of making the same.
US08283323B2 Withanolide compounds as inhibitors of fibrosis and identification of molecular targets for anti-fibrotic drug development
Provided are methods for screening for drugs effective for treating fibrotic conditions. One screening method comprises exposing a cell to a test compound, monitoring the effect of the test compound on the amount or form of a cell molecule, comparing the amount or form of the cell molecule with the result obtained by treatment of the cell with an anti-fibrotic -effective amount of a withanolide compound, and selecting a drug effective for treating a fibrotic disease based on the ability of the test compound to provide the effect obtained by the withanolide compound on the cell molecule. Also provided is a method of treating a fibrotic disease comprising administering an anti-fibrotic effective amount of a withanolide compound to a mammal in need of treatment for fibrosis.
US08283322B2 Formulations for nonsurgical exogenous crosslink therapy
Improved methods and compositions for the treatment of native tissues with crosslinkers are provided. The methods and compositions will find particular use in increasing resistance to tearing, fissuring, rupturing, and/or delamination.
US08283319B2 Therapeutic application of Kazal-type serine protease inhibitors
The present invention relates to the therapeutic application of the Kazal-type serine protease inhibitor Infestin or domains thereof or modified Kazal-type serine protease inhibitors based on Infestin homologs, which prevent the formation and/or stabilization of three-dimensional arterial or venous thrombi by interfering with proteins involved in activation of the so-called intrinsic coagulation pathway. The present invention also relates to the use of Kazal-type serine protease inhibitors or fragments thereof or modified Kazal-type serine protease inhibitors in the treatment or prophylaxis of a condition or disorder related to arterial thrombus formation, i.e. stroke or myocardial infarction, inflammation, complement activation, fibrinolysis, angiogenesis and/or diseases linked to pathological kinin formation such as hypotonic shock, edema including hereditary angioedema, bacterial infections, arthritis, pancreatitis, or articular gout, Disseminated Intravasal Coagulation (DIC) and sepsis.
US08283318B2 Aquaretic and natriuretic polypeptides lacking vasodilatory activity
This document provides aquaretic and natriuretic polypeptides. For example, this document provides polypeptides having aquaretic and/or natriuretic activities. In some cases, a polypeptide provided herein can have aquaretic and natriuretic activities, while lacking the ability to lower blood pressure. This document also provides methods and materials for inducing aquaretic and/or natriuretic activities within a mammal.
US08283314B1 Skin care compositions
Dermatological and cosmetic compositions and methods are provided to reduce the appearance of biological and/or environmentally-caused aging.
US08283313B2 Methods of increasing platelet and hematopoietic stem cell production
A method of increasing hematopoietic stem cell production is disclosed. The method includes administering a TPO mimetic compound to a subject. Pharmaceutical compositions including a TPO mimetic compound and a pharmaceutically acceptable carrier are also disclosed.
US08283307B2 Treatment of fibrotic disease
The invention relates to the use of INSP035 for treatment and/or prevention of fibrotic diseases, in particular of scleroderma.
US08283305B2 Cleaning implement with erodible foam substrate and controlled release system of active agent
A cleaning implement comprises an erodible foam substrate, such as a melamine foam substrate and a controlled release system comprising an active agent. The controlled release system comprises a component selected from the group consisting of a polymer matrix, a microcapsule, a particulate porous carrier, a complexing agent, a semi-permeable film and a combination thereof and the active agent is selected from the group consisting of a surfactant, a bleaching agent, a limescale reducing agent, a biocide, a solvent and a mixture thereof.
US08283302B2 Alkyl polypentosides and alkyl polyglucosides (C8-C11) used for enhanced food soil removal
The invention comprises a hard surface cleaning composition including an environmentally friendly, surfactant derived from renewable bio-based resources. The cleaning composition includes a mixture of alkyl polypentosides and alkyl polyglucosides having primarily between 8 and 11 carbon atoms as a surfactant, an acid source, an optional solvent, a water conditioning agent and water. The hard surface cleaner is preferably substantially free of alkyl phenol ethoxylates and is effective at removing food soils including 20% protein.
US08283298B2 Mineral oils with improved conductivity and cold flowability
Mineral oil distillates having an aromatics content of less than 21% by weight, a water content of less than 150 ppm and a conductivity of at least 50 pS/m, and comprising from 0.1 to 200 ppm of at least one alkylphenol-aldehyde resin (constituent I) which includes a structural element of the formula in which R5 is C1-C200-alkyl or C2-C200-alkenyl, O—R6 or O—C(O)—R6, R6 is C1-C200-alkyl or C2-C200-alkenyl and n is from 2 to 100, and from 0.1 to 200 ppm of at least one polar oil-soluble nitrogen compound (constituent II), excluding those mineral oil distillates in which between 0.001 and 10 ppm of an oil-soluble, organic sulfonic acid-ammonium salt are present.
US08283296B2 Lubricant for hot forging applications
A substantially lead-free lubricant for use in hot forging of metals, especially forging of aluminum and aluminum alloy components. The lubricant comprises one or more oils, graphite, and one or more phosphorus-based additives. Additional additives, such as metallic lubricants and dispersants may also be included. The lubricant does not burn when subjected to temperatures in excess of 300° C.
US08283295B1 Oil solids precipitation
Precipitation vessel for precipitation of flocculants from lubricating oil includes a hollow housing having an interior volume capable of containing oil; an entry port capable of allowing oil to enter into the interior volume; a stirrer capable of stirring contained oil; a heater capable of heating the contained oil; a product exit port capable of allowing oil to exit the interior volume; an upper exterior access port; and a lower exterior access port. Contaminated lubricating oil can be cleaned from solid particulates by a method of providing a vessel for containing oil; providing contaminated lubricating oil to the vessel; contacting the contaminated lubricating oil with a coagulant, and, maintaining the resulting mixture at a mildly elevated temperature throughout the vessel, inducing flocculation of solid particles and settlement of flocculated particles under low thermo-current, if not thermo-current-free, conditions; and drawing off lubricating oil cleaned from settled flocculated solid particles. The vessel or method can be employed as part of a system for reclaiming used lubricating oil, which, for example, may also employ vacuum separation of gasses, water and solvents under mild temperature conditions.
US08283289B2 Thermal transfer sheet
An object of the present invention is to provide a thermal transfer sheet provided with a black dye layer which can form a black image having jet-black color tone, small gradation difference of black and high resistance to light, and which has little offset of dyes to a back side layer during storage in a wound state. The above object is achieved by a thermal transfer sheet comprising a substrate, a heat resistant slip layer provided on one side of the substrate, and a black dye layer containing a dye and binder provided on the other side of the substrate, wherein the black dye layer contains 2 or 3 kinds of specific magenta dyes and 2 or 3 kinds of cyan dyes in the specific weight ratios with respect to a specific yellow dye.
US08283283B2 Thermal labels
A direct thermal label and methods of making thereof are provided. In one embodiment, a direct thermal label comprising a first substrate and a thermal barrier coating is provided, wherein the first substrate has a thermally sensitive coating situated over the thermal barrier coating on at least a first side thereof.
US08283281B2 Catalyst for purification of automobile exhaust gas and method for manufacturing the same
A catalyst for purification of automobile exhaust gas comprising: a support and rhodium supported on the support in an atomic state, wherein an amount of the rhodium supported is 0.05 to 0.30% by mass relative to the total amount of the support and the rhodium, 50 at. % or more of the rhodium is supported on the support as two-atom clusters of rhodium, and an average distance between adjacent ones of the two-atom clusters is 1.0 nm or more.
US08283279B2 Ultradispersed catalyst compositions and methods of preparation
The present invention relates generally to ultradispersed catalyst compositions and methods for preparing such catalysts. In particular, the invention provides catalyst composition of the general formula: BxMyS[(1.1 to 4.6)y+(0.5 to 4)x] where B is a group VIIIB non-noble metal and M is a group VI B metal and 0.05≦y/x≦15.
US08283265B2 Method to enhance charge trapping
Methods of improving charge trapping are disclosed. One such method includes forming an oxide-nitride-oxide tunnel stack and a silicon nitride layer on the oxide-nitride-oxide tunnel stack. This silicon nitride layer is implanted with ions. These ions may function as electron traps or as fields. The silicon nitride layer may be part of a flash memory device.
US08283263B2 Integrated circuit system including nitride layer technology
An integrated circuit method for manufacturing an integrated circuit system including loading a wafer into a processing chamber and pre-purging the processing chamber with a first ammonia gas. Depositing a first nitride layer over the wafer and purging the processing chamber with a second ammonia gas. Depositing a second nitride layer over the first nitride layer that is misaligned with the first nitride layer. Post-purging the processing chamber with a third ammonia gas and purging the processing chamber with a nitrogen gas.
US08283261B2 Radical oxidation process for fabricating a nonvolatile charge trap memory device
A method for fabricating a nonvolatile charge trap memory device is described. The method includes providing a substrate having a charge-trapping layer disposed Thereon. A portion of the charge-trapping layer is then oxidized to form a blocking dielectric layer above the charge-trapping layer by exposing the charge-trapping layer to a radical oxidation process.
US08283260B2 Process for restoring dielectric properties
A method for preparing an interlayer dielectric to minimize damage to the interlayer's dielectric properties, the method comprising the steps of: depositing a layer of a silicon-containing dielectric material onto a substrate, wherein the layer has a first dielectric constant and wherein the layer has at least one surface; providing an etched pattern in the layer by a method that includes at least one etch process and exposure to a wet chemical composition to provide an etched layer, wherein the etched layer has a second dielectric constant, and wherein the wet chemical composition contributes from 0 to 40% of the second dielectric constant; contacting the at least one surface of the layer with a silicon-containing fluid; optionally removing a first portion of the silicon-containing fluid such that a second portion of the silicon-containing fluid remains in contact with the at least one surface of the layer; and exposing the at least one surface of the layer to UV radiation and thermal energy, wherein the layer has a third dielectric constant that is restored to a value that is at least 90% restored relative to the second dielectric constant.
US08283259B2 Methods of removing a metal nitride material
A method of removing a metal nitride material is disclosed. The method comprises forming a semiconductor device structure comprising an exposed metal material and an exposed metal nitride material. The semiconductor device structure is subjected to a solution comprising water, ozone, and at least one additive to remove the exposed metal nitride material at a substantially greater rate than the exposed metal material.
US08283255B2 In-situ photoresist strip during plasma etching of active hard mask
A method for etching features in a silicon layer is provided. A hard mask layer is formed over the silicon layer. A photoresist layer is formed over the hard mask layer. The hard mask layer is opened. The photoresist layer is stripped by providing a stripping gas; forming a plasma with the stripping gas by providing a high frequency RF power and a low frequency RF power, wherein the low frequency RF power has a power less than 50 watts; and stopping the stripping gas when the photoresist layer is stripped. The opening the hard mask layer and the stripping the photoresist layer are performed in a same chamber.
US08283253B2 Pattern forming method, semiconductor device manufacturing method and semiconductor device manufacturing apparatus
A pattern forming method for forming a pattern serving as a mask, includes a process for forming a first pattern 105, a process for trimming a width of the first pattern 105, a process for forming a boundary layer 106 on a surface of the first pattern 105, a process for forming a second mask material layer 107 on a surface of the boundary layer 106, a process for removing a part of the second mask material layer 107 to expose top portions of the boundary layer 106, and a process for exposing the first pattern 105 and forming a second pattern having the second mask material layer 107 at a top portion thereof by etching the boundary layer 106.
US08283250B2 Semiconductor device and method of forming a conductive via-in-via structure
A semiconductor device is made from a semiconductor wafer containing semiconductor die separated by a peripheral region. A conductive via-in-via structure is formed in the peripheral region or through an active region of the device to provide additional tensile strength. The conductive via-in-via structure includes an inner conductive via and outer conductive via separated by insulating material. A middle conductive via can be formed between the inner and outer conductive vias. The inner conductive via has a first cross-sectional area adjacent to a first surface of the semiconductor device and a second cross-sectional area adjacent to a second surface of the semiconductor device. The outer conductive via has a first cross-sectional area adjacent to the first surface of the semiconductor device and a second cross-sectional area adjacent to the second surface of the semiconductor device. The first cross-sectional area is different from the second cross-sectional area.
US08283248B2 Methods of manufacturing semiconductor devices
A method of manufacturing a semiconductor device includes forming a plurality of preliminary gate structures, forming a capping layer pattern on sidewalls of the plurality of preliminary gate structures, and forming a blocking layer on top surfaces of the plurality of preliminary gate structures and the capping layer pattern such that a void is formed therebetween. The method also includes removing the blocking layer and an upper portion of the capping layer pattern such that at least the upper sidewalls of the plurality of preliminary gate structures are exposed, and a lower portion of the capping layer pattern remains on lower sidewalls of the preliminary gate structures. The method further includes forming a conductive layer on at least the upper sidewalls of the plurality of preliminary gate structures, reacting the conductive layer with the preliminary gate structures, and forming an insulation layer having an air gap therein.
US08283244B2 Method for forming one transistor DRAM cell structure
A one-transistor dynamic random access memory (DRAM) cell includes a transistor which has a first source/drain region, a second source/drain region, a body region between the first and second source/drain regions, and a gate over the body region. The first source/drain region includes a Schottky diode junction with the body region and the second source/drain region includes an n-p diode junction with the body region.
US08283242B2 Method of removing photoresist
A method includes forming a photoresist pattern over a certain portion of a material layer to expose an ion implantation region, implanting impurities in the ion implantation region of the material layer using the photoresist pattern as an ion implantation barrier, and removing the photoresist pattern using plasma of a gas mixture including a hydrocarbon-based gas.
US08283241B2 Dopant implanting method and doping apparatus
A dopant device includes: a dopant holder that holds Ge which is solid at normal temperature and liquefies the Ge near a surface of the semiconductor melt, the dopant holder including a communicating hole for delivering the liquefied Ge downwardly; a cover portion for covering the Ge held by the dopant holder; and a vent provided on the cover portion for communicating with the outside. A dopant injecting method is carried out using such a dopant device, the dopant injecting method including: loading Ge dopant in a solid state into the doping device; liquefying the solid Ge dopant loaded into the doping device while holding the doping device at a predetermined height from a surface of a semiconductor melt; and doping the semiconductor melt with the liquefied Ge that is flowed from the communicating hole.
US08283239B2 Process for growth of low dislocation density GaN
High quality free standing GaN is obtained using a new modification of the Epitaxial Lateral Overgrowth technology in which 3D islands or features are created only by tuning the growth parameters. Smoothing these islands (2D growth) is achieved thereafter by setting growth conditions producing enhanced lateral growth. The repetition of 3D-2D growth results in multiple bending of the threading dislocations thus producing thick layers or free standing GaN with threading dislocation density below 106 cm−2.
US08283228B2 Method of making ultrahigh density vertical NAND memory device
Monolithic, three dimensional NAND strings include a semiconductor channel, at least one end portion of the semiconductor channel extending substantially perpendicular to a major surface of a substrate, a plurality of control gate electrodes having a strip shape extending substantially parallel to the major surface of the substrate, the blocking dielectric comprising a plurality of blocking dielectric segments, a plurality of discrete charge storage segments, and a tunnel dielectric located between each one of the plurality of the discrete charge storage segments and the semiconductor channel.
US08283227B2 Method for manufacturing semiconductor memory device
In a method for manufacturing a semiconductor memory device, a three dimensional lower electrode including a titanium nitride film is formed on a semiconductor substrate, and a dielectric film is formed on the surface of the lower electrode. After a first upper electrode is formed at a temperature that the crystal of the dielectric film is not grown on the surface of the dielectric film, the first upper electrode and the dielectric film are heat-treated at a temperature that the crystal of the dielectric film is grown to convert at least a portion of the dielectric film into a crystalline state. Thereafter, a second upper electrode is formed on the surface of the first upper electrode.
US08283226B2 Method for manufacturing semiconductor device
A method of manufacturing a semiconductor device includes forming a first cap film over gate electrodes formed in a first active region and a second active region, etching the first cap film over the first active region, forming a second cap film over the gate electrodes formed in the first active region and the second active region, etching the second cap film over the first active region, etching the first active region using the gate electrodes to form concave portions in the first active region, and embedding a semiconductor material in the concave portions.
US08283225B2 Enhancing selectivity during formation of a channel semiconductor alloy by a wet oxidation process
High-k metal gate electrode structures are formed on the basis of a threshold adjusting semiconductor alloy formed in the channel region of one type of transistor, which may be accomplished on the basis of selective epitaxial growth techniques using an oxide hard mask growth mask. The hard mask may be provided with superior thickness uniformity on the basis of a wet oxidation process. Consequently, this may allow re-working substrates prior to the selective epitaxial growth process, for instance in view of queue time violations, while also providing superior transistor characteristics in the transistors that do not require the threshold adjusting semiconductor alloy.
US08283224B2 Ammonia pre-treatment in the fabrication of a memory cell
A method of manufacturing a memory cell 200. The method comprises forming a memory stack 215. Forming the memory stack includes pre-treating an insulating layer 210 in a substantially ammonia atmosphere for a period of more than 5 minutes to thereby form a pre-treated insulating layer 310. Forming the memory stack also includes depositing a silicon nitride layer on the pre-treated insulating layer.
US08283223B2 Method of manufacturing semiconductor device and semiconductor device
A method of manufacturing a semiconductor device includes: forming a gate insulating film over a semiconductor substrate; forming a mask that has an opening at a position corresponding to the gate insulating film formed in an NMOSFET forming region and covers the gate insulating film; forming a first metal layer over the gate insulating film disposed in the NMOSFET forming region and the mask formed in a PMOSFET forming region; and performing a heat treatment to thermally diffuse a metal material forming the first metal layer into the gate insulating film formed in the NMOSFET forming region.
US08283221B2 Configuration and manufacturing method of low-resistance gate structures for semiconductor devices and circuits
The present invention provides methods for fabricating devices with low resistance structures involving a lift-off process. A radiation blocking layer is introduced between two resist layers in order to prevent intermixing of the photoresists. Cavities suitable for the formation of low resistance T-gates or L-gates can be obtained by a first exposure, developing, selective etching of blocking layer and a second exposure and developing. In another embodiment, a low resistance gate structure with pillars to enhance mechanical stability or strength is provided.
US08283216B2 Liquid crystal display device and method for manufacturing the same
As a substrate gets larger, time of manufacture is increased due to the repetition of film formations and etchings; waste disposal costs of etchant and the like are increased; and material efficiency is significantly reduced. A base film for improving adhesion between a substrate and a material layer formed by a droplet discharge method is formed in the invention. Further, a manufacturing method of a liquid crystal display device according to the invention includes at least one step for forming the following patterns required for manufacturing a liquid crystal display device without using a photomask: a pattern of a material layer typified by a wiring (or an electrode) pattern, an insulating layer pattern; or a mask pattern for forming another pattern.
US08283214B1 Methods for forming nickel oxide films for use with resistive switching memory devices
Methods for forming a NiO film on a substrate for use with a resistive switching memory device are presenting including: preparing a nickel ion solution; receiving the substrate, where the substrate includes a bottom electrode, the bottom electrode utilized as a cathode; forming a Ni(OH)2 film on the substrate, where the forming the Ni(OH)2 occurs at the cathode; and annealing the Ni(OH)2 film to form the NiO film, where the NiO film forms a portion of a resistive switching memory element. In some embodiments, methods further include forming a top electrode on the NiO film and before the forming the Ni(OH)2 film, pre-treating the substrate. In some embodiments, methods are presented where the bottom electrode and the top electrode are a conductive material such as: Ni, Pt, Ir, Ti, Al, Cu, Co, Ru, Rh, a Ni alloy, a Pt alloy, an Ir alloy, a Ti alloy, an Al alloy, a Cu alloy, a Co alloy, an Ru alloy, and an Rh alloy.
US08283212B2 Method of making a copper wire bond package
A method for making a wire bond package comprising the step of providing a lead frame array comprising a plurality of lead frame units therein, each lead frame unit comprises a first die pad and a second die pad each having a plurality of tie bars connected to the lead frame array, a plurality of reinforced bars interconnecting the first and second die pads; the reinforced bars are removed after molding compound encapsulation.
US08283211B2 Method of making a semiconductor chip assembly with a bump/base heat spreader and a dual-angle cavity in the bump
A method of making a semiconductor chip assembly includes providing a bump and a ledge, wherein the bump includes first, second and third bent corners that shape a cavity, mounting an adhesive on the ledge including inserting the bump into an opening in the adhesive, mounting a conductive layer on the adhesive including aligning the bump with an aperture in the conductive layer, then flowing the adhesive between the bump and the conductive layer, solidifying the adhesive, then providing a conductive trace that includes a pad, a terminal and a selected portion of the ledge, providing a heat spreader that includes the bump, then mounting a semiconductor device on the bump within the cavity, electrically connecting the semiconductor device to the conductive trace and thermally connecting the semiconductor device to the heat spreader.
US08283207B2 Methods for forming through-substrate conductor filled vias, and electronic assemblies formed using such methods
Through substrate vias for back-side electrical and thermal interconnections on very thin semiconductor wafers without loss of wafer mechanical strength during manufacturing are provided by: forming desired device regions with contacts on the front surface of an initially relatively thick wafer; etching via cavities partly through the wafer in the desired locations; filling the via cavities with a conductive material coupled to some device region contacts; mounting the wafer with its front side facing a support structure; thinning the wafer from the back side to expose internal ends of the conductive material filled vias; applying any desired back-side interconnect region coupled to the exposed ends of the filled vias; removing the support structure and separating the individual device or IC assemblies so as to be available for mounting on a further circuit board, tape or larger circuit.
US08283205B2 Semiconductor device and method of forming stepped interconnect layer for stacked semiconductor die
A semiconductor die has a first semiconductor die mounted to a carrier. A plurality of conductive pillars is formed over the carrier around the first die. An encapsulant is deposited over the first die and conductive pillars. A first stepped interconnect layer is formed over a first surface of the encapsulant and first die. The first stepped interconnect layer has a first opening. A second stepped interconnect layer is formed over the first stepped interconnect layer. The second stepped interconnect layer has a second opening. The carrier is removed. A build-up interconnect structure is formed over a second surface of the encapsulant and first die. A second semiconductor die over the first semiconductor die and partially within the first opening. A third semiconductor die is mounted over the second die and partially within the second opening. A fourth semiconductor die is mounted over the second stepped interconnect layer.
US08283204B2 Optimized lid attach process for thermal management and multi-surface compliant heat removal
A multi-surface compliant heat removal process that includes identifying components to share a heat rejecting device; applying non-adhesive film to the components; identifying a primary component of the components; and applying phase change material on each of the components, other than the primary component. The phase change material is placed on top of the non-adhesive film. The process also includes placing the heat rejecting device on the corresponding components and removing the heat rejecting device from the corresponding components. The phase change material and the non-adhesive film remain with the heat rejecting device. The process also includes reflowing the phase change material on the heat rejecting device; removing the non-adhesive film from the heat rejecting device; placing a heatsink-attach thermal interface material on the components; and placing the heat rejecting device on the corresponding components.
US08283202B2 Single mask adder phase change memory element
A method of fabricating a phase change memory element within a semiconductor structure includes etching an opening to an upper surface of a bottom electrode, the opening being formed of a height equal to a height of a metal region at a same layer within the semiconductor structure, depositing phase change material within the opening, recessing the phase change material within the opening, and forming a top electrode on the recessed phase change material.
US08283201B2 Preparation of lanthanide-containing precursors and deposition of lanthanide-containing films
Methods and compositions for depositing rare earth metal-containing layers are described herein. In general, the disclosed methods deposit the precursor compounds comprising rare earth-containing compounds using deposition methods such as chemical vapor deposition or atomic layer deposition. The disclosed precursor compounds include a cyclopentadienyl ligand having at least one aliphatic group as a substituent and an amidine ligand.
US08283198B2 Resistive memory and methods of processing resistive memory
Resistive memory and methods of processing resistive memory are described herein. One or more method embodiments of processing resistive memory include forming a resistive memory cell material on an electrode having an access device contact, and forming a heater electrode on the resistive memory cell material after forming the resistive memory cell material on the electrode such that the heater electrode is self-aligned to the resistive memory cell material.
US08283193B2 Integrated circuit system with sealring and method of manufacture thereof
A method of manufacture an integrated circuit system includes: forming an insulation region in a base layer; filling an insulator in the insulation region around a perimeter of a main chip region; forming a contact directly on and within planar extents of the insulator; and forming an upper layer over the contact to protect the main chip region.
US08283191B2 Method for producing an optoelectronic component and optoelectronic component
In a method for producing an optoelectronic component, a growth substrate having a first coefficient of thermal expansion is provided. A multilayered buffer layer sequence is applied thereto. A layer sequence having a second coefficient of thermal expansion—different than the first coefficient of thermal expansion—is subsequently deposited epitaxially. It furthermore comprises an active layer for emitting electromagnetic radiation. A carrier substrate is subsequently applied on the epitaxially deposited layer sequence. The growth substrate is removed and the multilayered buffer layer sequence is structured in order to increase a coupling-out of electromagnetic radiation. Finally, contact is made with the epitaxially deposited layer sequence.
US08283188B2 Method for fabricating light emitting diode chip
A method for fabricating a light emitting diode chip is provided. Firstly, a semiconductor device layer is formed on a substrate. Afterwards, a current spreading layer is formed on a portion of the semiconductor device layer. Then, a current blocking layer and a passivation layer are formed on a portion of the semiconductor device layer not covered by the current spreading layer. Finally, a first electrode is formed on the current blocking layer and the current spreading layer. Moreover, a second electrode is formed on the semiconductor device layer.
US08283187B2 Photovoltaic device and method for making
One aspect of the present invention provides a device that includes a substrate; a first semiconducting layer; a transparent conductive layer; a transparent window layer. The transparent window layer includes cadmium sulfide and oxygen. The device has a fill factor of greater than about 0.65. Another aspect of the present invention provides a method of making the device.
US08283185B2 Magnetically susceptible particles and apparatuses for mixing the same
The present invention includes a magnetically susceptible polymer component, a method of making the same, and apparatuses and systems for mixing, separating or localizing a magnetically susceptible polymer compound in a reaction. The magnetically susceptible polymer component includes a polymer and a magnetically susceptible particle of a predetermined size, which yields a component having a much-improved magnetic reactivity due to the increase in magnetic material by mass percentage. The apparatuses and systems of the present invention employ controllable magnetic fields distributable in perpendicular directions in order to precisely control the orientation, position and relative motion of any magnetically susceptible components within a reaction vessel.
US08283183B2 Detecting method, detection device and detection kit
A detection device and a detecting method using the detection device are provided in which a magnetic particle is used as a marker particle, and the ratio of a region with reversed magnetization to the whole area of a free layer of a magnetoresistive effect film is increased by a stray magnetic field generated through a biochemical reaction from the magnetic particle remaining on a surface of the magnetoresistive effect film, so that a large detection signal is obtained and obtained detection data can be stored with stability.
US08283182B2 Agglutination based sample testing device
A sample testing device for testing for the presence of a component of interest in a liquid sample comprises: (a) at least one capillary pathway which has an upstream end and a downstream end and which incorporates a reagent system capable of causing agglutination with said component to be detected (the test capillary); (b) preferably, but optionally, at least one capillary pathway having an upstream end and a downstream end (the control capillary); (c) a sampling region to which the liquid sample is applied and from which the sample is able to enter the upstream ends of the test capillary(s) and if present the control capillary(s); (d) a power source; (c) detection arrangements electrically associated with said power source for detecting the presence of liquid at a downstream region of said testing capillary(s) and if present the control capillary(s); (f) display means operated by said power source for indicating the result of the test; and (g) signal processing means associated with the power source, detection arrangement and display means for evaluating the result of the test and providing said result on the display means. The device may be used for a pregnancy test, more particularly for determining the presence of hCG in urine.
US08283181B2 Capillary pins for high-efficiency microarray printing device
This invention provides improved components (e.g. array “pins”, print head, substrate platen, print head platen, and the like) for microarray printing devices as well as microarray printing devices incorporating such components. In one embodiment, this invention provides a microarray print head comprising a plurality of glass or quartz spotting capillaries disposed in a support that maintains a fixed spacing between the spotting capillaries and that permits the spotting capillaries to move in a direction parallel to the long axis of the capillaries.
US08283180B2 Periodic acid-schiff staining with detection in the infrared range
Provided is a method of detecting the presence and quantitating the amount of glycogen from a biological sample. This method employs PAS staining with detection in the infrared range.
US08283175B2 Test device for determining an analyte concentration
A test device for determining the concentration of at least one analyte in a sample using a element is proposed. The test device can be used particularly for glucose measurement, in particular blood glucose measurement, cholesterol measurement and/or coagulation measurement. The test device according to the invention comprises a housing with a closed state and an opened state, and a storage device for receiving at least one test element. The at least one test element is typically designed as a strip-shaped test element, and the storage device typically comprises a magazine. The magazine comprises a plurality of cavities, and the test elements are received substantially parallel to one another in the cavities. A measuring device and a dispensing device are also provided. The dispensing device comprises means for conveying the at least one test element from at least one storage position of the storage device during opening of the housing.
US08283168B2 Mesoderm and definitive endoderm cell populations
The present invention provides cell populations that are enriched for mesendoderm and mesoderm, and cell populations that are enriched for endoderm. The cell populations of the invention are useful for generating cells for cell replacement therapy. The present invention further provides a method of generating hepatocytes, cell populations enriched for hepatocytes, and a method of hepatocyte replacement therapy.
US08283167B2 Preparation of annexin derivatives
Labeled annexin is formed by reacting annexin or a modified annexin with a phosphatidylserine group or an analogue of phosphatidylserine. This phosphatidylserine annexin conjugate is then reacted with an appropriate label to form a labeled annexin and the annexin is separated from the phosphatidylserine group. The reaction between the phosphatidylserine group and the annexin is calcium ion concentration dependent. Therefore, the reaction can be promoted by having a high calcium ion concentration and the separation of the phosphatidyl group from the annexin group is facilitated by reducing the calcium ion concentration preferably by addition of an appropriate calcium chelating agent.
US08283164B2 Liver engrafting cells, assays, and uses thereof
A substantially enriched mammalian hepatic liver engrafting cell population is provided. Methods are provided for the isolation and culture of this liver engrafting cell, for example, a cell population containing human liver engrafting cells wherein at least one cell in the population is HLAlow/neg; and expresses at least one marker selected from the group consisting of albumin; 5E12; Ep-Cam; CD49f; and E-Cadherin. The progenitor cells are obtained from a variety of sources, including fetal and adult tissues. The cells are useful in transplantation, for experimental evaluation, and as a source of lineage and cell specific products, including mRNA species useful in identifying genes specifically expressed in these cells, and as targets for the discovery of factors or molecules that can affect them.
US08283163B2 Method for production of dendritic cell
The present invention provides methods for producing DCs, which comprise the step of culturing DC precursor cells in the presence of multiple cytokines, dendritic cells produced thereby, and uses thereof. The methods of the present invention enable production of large quantities of DC precursors with a high ability to differentiate into DCs. The present invention enables one to obtain large quantities of DCs from a small number of DC precursor cells, and therefore makes it easier to increase the number of DCs for administration in DC-based anti-tumor immunotherapy, treatment of infection, and such. Thus, an enhancement is expected for the effect of DC vaccines.
US08283159B2 Fermenter for producing biogas from organic material
The invention relates to a fermenter (10) for producing biogas from organic material, having a fermentation chamber (11) with a substantially round basal surface to receive fermentation material; arranged, in the peripheral region of the fermentation chamber, filling means (12) for substrate to be fermented; arranged, above the fermentation chamber, an unpressurized gas store (13) with gas discharging means (14); stirring means (15); a settling chamber (16) with overflow rim; and also pumping means (17) for the continuous or batchwise removal of fermentation material from the fermentation chamber and introduction into the settling chamber.
US08283157B2 System and method for increasing polymer/nanopore interactions
An electrolytic system includes an analyte chamber having an access port for introducing a sample containing a molecules of interest, such as DNA. Electrodes create an electric field along a length of the analyte chamber to drive molecules toward an interaction region containing a nanopore, thereby increasing the arrival rate of molecules at the nanopore. Additional electrodes may be utilized to create an electric field through the nanopore to drive a molecule into the nanopore. A current sensor may be utilized to count, discriminate or characterize the molecules as they interact with the nanopore. Advantageously, system can be utilized for unamplified DNA sequencing.
US08283156B2 Method and apparatus for assay based on light diffraction
The present invention relates to a method and apparatus for detecting analytes in a medium, and more particularly the present invention relates to an assay based on light diffraction which appears or changes upon the binding of analytes to their specific receptors laid out in patterns on a substrate, which has high sensitivity due to the appropriate choice of such patterns. The present invention is based on the principle that the pattern of recognition elements, which gives rise to the diffraction of the incident light in a diffraction-based assay, can be chosen in such a way so as to facilitate detection, and to enhance the signal to be detected compared to known gratings such as parallel straight lines. In one aspect the substrate itself has a surface topography designed to enhance the diffraction pattern signals. In another aspect the substrate is a diffractive optic element having the analyte-specific receptors affixed to the optic element. In another aspect the diffractive optic element is used as a master stamp for producing patterns of analyte-specific receptors which give the signal enhancements.
US08283153B2 Mycelium structures containing nanocomposite materials and method
A method of making a molded part, including forming a liquid aggregate from a mixture of finely ground aggregate and a fluid. A mixture of a fungal inoculum and the liquid aggregate is formed. Nanoparticles are homogenously distributed throughout the mixture. The mixture is inserted into a mold cavity. Live mycelium is grown to fill the mold cavity. The live mycelium is heated to terminate further growth and develop a formed part.
US08283152B2 Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism
Disclosed is a strain of Escherichia sp., capable of producing O-acetyl homoserine in high yield, with the introduction and enhancement therein of the activity of: homoserine acetyl transferase, aspartokinase and homoserine dehydrogenase; and at least one enzyme selected from a group consisting of phosphoenolpyruvate carboxylase, aspartate aminotransferase and aspartate semi-aldehyde dehydrogenase. Also, a method of producing O-acetyl homoserine using the strain is provided.
US08283148B2 DNA polymerase compositions for quantitative PCR and methods thereof
The invention relates to the generation and characterization of Archaeal DNA polymerase mutants with deficient 3′-5′ exonuclease activity and reduced base analog detection activity. The invention further provides for Archaeal DNA polymerase mutants with deficient 3′-5′ exonuclease activity and reduced base analog detection activity containing additional mutations that modulate other DNA polymerase activities including DNA polymerization or reverse transcriptase activity. The invention also discloses methods and applications of DNA polymerases with deficient 3′-5′ exonuclease activity and reduced base analog detection activity.
US08283146B2 Processing enzymes fused to basic protein tags
The invention is related to processing enzyme comprising an N-terminally attached tag derived from highly basic proteins from thermophilic bacteria. The processing enzymes are useful for modifying proteins. They can be produced in high yields and can be effectively separated from the modified protein after use.
US08283145B2 Chondroitin-producing bacterium and method of producing chondroitin
Chondroitin is produced by culturing a UDP-glucuronic acid-producing bacterium transfected with a kfoA gene derived from Escherichia coli K4 strain and a kfoC gene derived from Escherichia coli K4 strain and having chondroitin-producing ability. Chondroitin is collected from the bacterium.
US08283143B2 Enhanced production of fatty acid derivatives
Genetically engineered cells and microorganisms are provided that produce fatty alcohols from the fatty acid biosynthetic pathway, as well as methods of their use.
US08283138B2 Method for the high level expression of active tumor necrosis receptor family member immunoglobulin fusion proteins
Methods for high level expression of active lymphotoxin-β receptor immunoglobulin chimeric proteins and their purification.
US08283136B2 Skin treatment compositions
This invention relates to Micrococcus luteus containing compositions useful for controlling skin disorders in which bacteria are a causative component. The invention also provides for a new strain of Micrococcus luteus useful in these compositions.
US08283132B2 Method and devices for treating individual biological cells
The invention relates to a method for treating a biological cell (1) including a cytoskeleton (3) enveloped by a cell membrane (2). The method includes the following steps: the biological cell (1) and a tool (10) are mutually oriented such that the tool (10) comes into contact with the biological cell (1); the tool (10) and the biological cell (1) are displaced in relation to each other; and a gap is formed in the molecular composite of the cell membrane (2) of the biological cell (1). During the displacement of the tool (10), the cytoskeleton (3) of the biological cell (1) has a state of equilibrium. The invention also relates to a cell manipulator for carrying out the inventive method.
US08283130B2 Protein fragments of virB10 and sero-detection of anaplasma phagocytophium
Disclosed are cloning and expression of a plurality of protein fragments of virB10, a Type IV Secretion System (TIVSS) in Anaplasma phagocytophilum. Such recombinant protein fragments are useful in the ELISA detection of anaplasma pathogen. The use of same as kits for ELISA is also disclosed.
US08283127B2 Detection system and uses therefor
A system for the detection of molecular associations, the system comprising: i) a first agent, comprising a first interacting group coupled to a first reporter component; ii) a second agent, comprising a second interacting group coupled to a second reporter component; iii) a third agent, comprising a third interacting group; iv) a modulator; and v) a detector; wherein proximity of the first and second reporter components generates a signal capable of detection by the detector; and wherein the modulator modulates the association of the second interacting group with the third interacting group; such that monitoring the signal generated by proximity of the first and second reporter components by the detector constitutes monitoring the association of the first and third agents.
US08283126B2 Voltage sensor domains of voltage-dependent ion channel proteins and uses thereof
A composition of matter suitable for use in identifying chemical compounds that bind to voltage-dependent ion channel proteins, the composition comprising a screening protein that comprises an ion channel voltage sensor domain of the ion channel protein immobilized on a solid support.
US08283121B2 Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions
The present invention relates to a method for identifying a target nucleotide sequence. This method involves forming a ligation product on a target nucleotide sequence in a ligase detection reaction mixture, amplifying the ligation product to form an amplified ligation product in a polymerase chain reaction (PCR) mixture, detecting the amplified ligation product, and identifying the target nucleotide sequence. Such coupling of the ligase detection reaction and the polymerase chain reaction permits multiplex detection of nucleic acid sequence differences.
US08283116B1 Methods of screening for compounds for treating spinal muscular atrophy using SMN mRNA translation regulation
The present invention provides compounds and assays for the identification and validation of compounds for use in the treatment of spinal muscular atrophy (SMA), in which said compounds up-regulate the post-transcriptional expression of SMN1 or SMN2.
US08283114B2 Genes of an otitis media isolate of nontypeable Haemophilus influenzae
The invention relates to the polynucleotide sequence of a nontypeable stain of Haemophilus influenzae (NTHi) and polypeptides encoded by the polynucleotides and uses thereof. The invention also relates to NTHi genes which are upregulated during or in response to NTHi infection of the middle ear and/or the nasopharynx.
US08283113B2 Compositions and methods for preventing and treating cancer via modulating UBE1L, ISG15 and/or UBP43
Compositions and methods of using compositions that induce UBE1L or a ubiquitin-like protein ISG15, or inhibit a deconjugase UBP43 to degrade oncogenic proteins and enhance apoptosis of cancer (neoplastic) or pre-cancerous (pre-neoplastic) cells are provided. Methods for the prevention or treatment of cancer via administration of these compositions are also provided.
US08283112B2 Photoresist processing methods
A photoresist processing method includes treating a substrate with a sulfur-containing substance. A positive-tone photoresist is applied on and in contact with the treated substrate. The method includes selectively exposing a portion of the photoresist to actinic energy and developing the photoresist to remove the exposed portion and to form a photoresist pattern on the substrate. The treating with a sulfur-containing substance reduces an amount of residual photoresist intended for removal compared to an amount of residual photoresist that remains without the treating.
US08283108B2 Method of applying patterned metallization to block filter resonators
An embodiment of the present invention provides a method of applying patterned metallization to a ceramic block comprising applying a photodefinable ink to said ceramic block; drying said ink; exposing said photodefinable ink to UV radiation through a predefined mask according to the thickness of the film to form a pattern; developing said pattern in a developer solution thereby forming a patterned ceramic block; and rinsing, drying and firing said patterned ceramic block.
US08283097B2 Process for producing toner for electrostatic charge image development toner for electrostatic charge image development
To provide a process for efficiently producing a toner for developing an electrostatic charge image, which is scarcely susceptible to aggregation of the toner and free from blocking during the storage or from soiling the image forming apparatus and which is excellent in image characteristics. A process for producing a toner for developing an electrostatic charge image, characterized by supplying a monomer into a dispersion containing wax and a polymerizable monomer having a C8-100 hydrocarbon group, carrying out the polymerization, followed by flocculation treatment.
US08283094B2 Method for fracturing and forming a pattern using circular characters with charged particle beam lithography
In the field of semiconductor production using shaped charged particle beam lithography, a method and system for fracturing or mask data preparation or proximity effect correction is disclosed, wherein a plurality of shots of circular or nearly-circular character projection characters, having at least two shots that overlap, can form a non-circular pattern on a surface. Methods for manufacturing a reticle and for manufacturing a substrate such as a silicon wafer by forming non-circular patterns on a surface using a plurality of circular or nearly-circular character projection shots, where at least two shots overlap, is also disclosed.
US08283088B2 Silane crosslinked structure-introduced fuel-cell polymer electrolyte membrane and fuel-cell electrode assembly having the same
An object is to provide an electrolyte membrane that maintains excellent cell characteristics for a long time under high temperature and low water retention, as this is the most important point in fuel cells.A process for producing a polymer electrolyte membrane for fuel cells is provided, which process comprises in sequence: forming graft molecular chains by graft-polymerization of a vinyl silane coupling agent on a polymer film substrate that has phenyl groups capable of holding sulfonic acid groups; introducing sulfonic acid groups into phenyl groups contained in the graft molecular chains; and hydrolyzing and condensing alkoxy groups contained in the graft molecular chains so that a silane crosslinked structure is introduced between the graft molecular chains. A polymer electrolyte membrane produced by the process is also provided.
US08283084B2 Hollow-shaped membrane electrode assembly for fuel cell and hollow-type fuel cell
There is provided a hollow-shaped membrane electrode assembly for a fuel cell capable of improving power density per unit volume, wherein the hollow-shaped membrane electrode assembly for a fuel cell comprises a hollow solid electrolyte membrane, an outer electrode layer formed on the outer circumferential surface of the solid electrolyte membrane and an inner electrode layer formed on the inner circumferential surface of the solid electrolyte membrane, and wherein the hollow-shaped membrane electrode assembly for a fuel cell is formed in the shape of a spiral.
US08283083B2 Fuel cell system
A fuel cell system including: a fuel cell supplied with a fuel gas to a fuel electrode thereof and air to an air electrode thereof; a fuel gas supplying device which supplies the fuel gas to the fuel electrode; an air supplying device which supplies air to the air electrode; a fuel gas pressure regulator which regulates fuel gas pressure at the fuel electrode; a purge valve which discharges exhaust fuel gas from the fuel electrode to the outside; and a controller. The controller continues power generation of the fuel cell, controlling the fuel gas pressure regulator to lower the fuel gas pressure at the fuel electrode, having the air supplying device continuing supplying air to the air electrode with the purge valve closed; and after the fuel gas pressure at the fuel electrode becomes equal to or lower than the atmospheric pressure, stops power generation of the fuel cell.
US08283082B2 Method of starting operation of fuel cell system
A fuel cell system includes a fuel cell, a battery, and a DC/DC converter capable of connecting the fuel cell and the battery on a power feeding circuit. A method of starting operation of the fuel cell system includes the steps of connecting a bypass line connected to a battery for bypassing the DC/DC converter to the power feeding circuit, and directly supplying electrical energy from the battery to an air compressor of an oxygen-containing gas supply apparatus through the bypass line in a state where the fuel cell is disconnected from the power feeding circuit.
US08283081B2 Membrane electrode assembly with hydrogenatable material for a fuel cell
The invention relates to a membrane-electrode assembly for a fuel cell with a proton-conducting membrane two catalyst layers adjoining both sides of the membrane, wherein the catalyst layers have an electrically conductive base material and at least one catalytic material deposited on the base material, and two gas diffusion layers adjoining the catalyst layers. The membrane and/or at least one of the catalyst layers and/or at least one of the gas diffusion layers includes at least one hydrogenatable material capable of binding hydrogen in a reversible exothermic hydrogenation operation by forming a hydride, depending on the temperature and/or pressure. The hydrogenatable material can be distributed in the gas diffusion layer and/or in the catalyst layer or can be present as a separate layer on at least one side of the gas diffusion electrode or the membrane.
US08283078B2 Carbon fuel particles used in direct carbon conversion fuel cells
A system for preparing particulate carbon fuel and using the particulate carbon fuel in a fuel cell. Carbon particles are finely divided. The finely dividing carbon particles are introduced into the fuel cell. A gas containing oxygen is introduced into the fuel cell. The finely divided carbon particles are exposed to carbonate salts, or to molten NaOH or KOH or LiOH or mixtures of NaOH or KOH or LiOH, or to mixed hydroxides, or to alkali and alkaline earth nitrates.
US08283076B2 Microbial fuel cells
A microbial fuel cell is provided according to embodiments of the present invention including electricigenic microbes containing at least about 0.075 milligrams of protein per square centimeter of the anode surface area. In particular embodiments, the electricigenic microbes are disposed on the anode such that at least about 90% of the portion of the anode surface area has a layer of electricigenic microbes, the layer greater than about 1 micron in thickness. This thickness is indicative of the layer including at least a first stratum of electricigenic microbes in direct contact with the anode and a second stratum of electricigenic microbes in direct contact with the first stratum such that the second stratum is in indirect contact with the anode.
US08283074B2 Electrolyte salts for nonaqueous electrolytes
Metal complex salts may be used in lithium ion batteries. Such metal complex salts not only perform as an electrolyte salt in a lithium ion batteries with high solubility and conductivity, but also can act as redox shuttles that provide overcharge protection of individual cells in a battery pack and/or as electrolyte additives to provide other mechanisms to provide overcharge protection to lithium ion batteries. The metal complex salts have at least one aromatic ring. The aromatic moiety may be reversibly oxidized/reduced at a potential slightly higher than the working potential of the positive electrode in the lithium ion battery. The metal complex salts may also be known as overcharge protection salts.
US08283073B2 Microporous polyolefin membrane
The present invention provides a microporous polyolefin membrane having a porosity of 45% to 85% wherein the microporous polyolefin membrane easily absorbs the strain produced when the membrane undergoes compression, and retains excellent permeability and excellent electrical insulation performance even after compression by setting the maximum pore diameter at 0.1 μm to 0.23 μm, the MD elastic modulus at 400 to 2,000 MPa, and the ratio MD elastic modulus/TD elastic modulus at 1.5 to 9.
US08283070B2 Anode active material and lithium battery using the same
An anode active material and a lithium battery employing the same are provided. In one embodiment of the anode active material, a —(CH2CH2O)— repeating unit is bonded to the surface of metal particles that contain metals that can be alloyed with lithium. The repeating unit prevents reactions between the metal particles and the electrolyte solution. Also, due to its elasticity, the repeating unit absorbs part of the volume expansion of the metal particles. The repeating unit also prevents the metal particles from condensing, thereby enhancing dispersion properties. Accordingly, the inventive anode active material has high capacity and excellent capacity retention during repeated charging and discharging, thereby providing a lithium battery with a long cycle life.
US08283067B2 Electric energy storage device and manufacturing method thereof
There is provided an electric energy storage device which has a connection structure with a high connection reliability and which can suppress any contact of an outer package body with a connection terminal with a simple structure. The electric energy storage device comprises a battery element 10 retained in an outer package body 20 having a metal layer 21b, a tabular internal lead 31 connected to the battery element 10, a tabular external lead 32, a connection terminal 33 electrically connecting the internal lead 31 with the external lead 32, an internal insulating member 41, and an external insulating member 43. Flanges 33T, 33B at both ends of the connection terminal 33 depress the external insulating member 43, the outer package body 20, and the internal insulating member 41 between the tabular external lead 32 and internal lead 31, and the external insulating member 43 and/or internal insulating member 41 is pressed in between a penetration shaft 33S of the connection terminal 33 and the metal layer 21b.
US08283066B2 Electrochemical cell with improved internal contact
Electrochemical battery cells with strip-like electrodes and having a pressure contact between a lead from one of the electrodes and a sidewall of the cell container. An electrochemical cell having a spiral wound electrode assembly having an internal lead in direct pressure contact with a lithium foil negative electrode free of a separate current collector and in contact with an inner portion of the cell container, wherein specified contact between the lead and lithium foil provides current flow between the container and foil.
US08283064B2 Electrode assembly and secondary battery using the same
An electrode assembly of a secondary battery includes an electrode group including a first electrode plate, a separator, and a second electrode plate that are stacked and wound, and a finishing tape attached to a predetermined region of a terminal portion of the electrode group. The finishing tape satisfies the equation Y1=tensile strength×thickness of finishing tape/modulus of elasticity, with Y1 ranging from 64 to 89. Alternatively, the finishing tape includes a film layer and an adhesive layer, and satisfies the equation Y2=tensile strength×thickness of film layer of finishing tape/modulus of elasticity, with Y2 ranging from 51 to 75. The finishing tape effectively prevents an increase in the thickness of a high-capacity secondary battery.
US08283062B2 Electrochemical cells utilizing taylor vortex flows
Electrochemical cells (10), such as fuel cells (12) and fuel reformers (14), with rotating elements or electrodes (34, 24) that generate Taylor Vortex Flows (28, 50) and Circular Couette Flows (58) in fluids such as electrolytes and fuels are disclosed.
US08283057B2 Heteroarylamine compound and organic light-emitting device including the same
Embodiments of the present invention are directed to heteroarylamine compounds and organic light-emitting devices including the heteroarylamine compounds. The organic light-emitting devices using the heteroarylamine compounds have high-efficiency, low driving voltages, high luminance and long lifespans.
US08283055B2 Material for light-emitting element, light-emitting element, light-emitting device, electronic device, and lighting device
A material for a light-emitting element is represented by a general formula (G1). In the general formula (G1), Ar1 represents a substituted or unsubstituted aryl group having 6 to 13 carbon atoms, Ar2, Ar3, and Ar4 each independently represent a substituted or unsubstituted arylene group having 6 to 13 carbon atoms, R1 to R8 independently represent hydrogen or an alkyl group having 1 to 4 carbon atoms, R11 represents an alkyl group having 1 to 4 carbon atoms or a substituted or unsubstituted aryl group having 6 to 13 carbon atoms, and R12 represents an alkyl group having 1 to 4 carbon atoms or a substituted or unsubstituted aryl group having 6 to 13 carbon atoms.
US08283052B2 Quinoxaline derivative, light-emitting element, light-emitting device, and electronic appliance
It is an object to provide a new substance excellent in electron-transporting property, and a light-emitting element and a light-emitting device using the substance. A quinoxaline derivative represented by the general formula (G1) is provided. In the general formula (G1), each of R1 to R4 represents hydrogen, an alkyl group having 1 to 4 carbon atoms, or an aryl group having 6 to 25 carbon atoms; and each of Ar1 and Ar2 represents an aryl group having 6 to 25 carbon atoms. Such a quinoxaline derivative is excellent in electron-transporting property and very effective as an electron-transporting material in a light-emitting element and the like.
US08283048B2 Thermal barrier coatings and articles made therefrom
A thermally sprayed coating, coating system and coated article are disclosed. The disclosed embodiments of the thermally sprayed coating, coating system and coated article use a customized ceramic powder comprising ceramic powder particles having an average particle size of about 25 to about 75 microns. In particular, the ceramic powder particles contain from about 70 to about 95 percent by weight of a zirconia-based component, with the balance being an (alumina+silica)-based component and wherein said ceramic powder particles comprise micronized sub-particles of the zirconia-based component and the (alumina+silica)-based component.
US08283045B2 Award for sporting event
The present invention is an award that serves as a trophy and as a golf club head cover. The cover of the award is positioned on a stand that is supported by a base or positioned on a golf club head as a golf club head cover.
US08283039B2 Vulcanized rubber laminate
The invention provides a vulcanized rubber laminate obtained by firmly bonding an unvulcanized epichlorohydrin rubber layer and an organic peroxide-containing fluororubber layer. The laminate is obtained by thermal adhesion a layer of an unvulcanized epichlorohydrin rubber composition to a layer of an unvulcanized fluororubber composition. The epichlorohydrin rubber composition comprises 1) an unvulcanized epichlorohydrin rubber containing 3 to 15 mol % of allyl glycidyl ether unit, 2) quinoxaline-based vulcanizing agents, mercaptotriazine-based vulcanizing agents or bisphenol-based vulcanizing agents, and 3) 1,8-diazabicyclo(5,4,0)undecene-7 salts, 1,5-diazabicyclo(4,3,0)nonene-5 salts, quaternary ammonium salts, quaternary phosphonium salts, basic white carbons or an alkaline metal salt of higher fatty acid the fluororubber composition comprises an fluororubber and an organic peroxide-based vulcanizing agent.
US08283038B2 Layered structure including graphene and an organic material having a conjugated system, and method of preparing the same
A layered structure including graphene, wherein a basal plane of the graphene is a (0001) plane; and a layer including an organic material having a conjugated system disposed on the graphene, wherein the layer comprising the organic material layer having the conjugated system is bound to the (0001) plane of the graphene by a π-π interaction, and a method of preparing the same.
US08283036B2 Composite nanoparticles containing organic ions
A composite nanoparticle comprising a nanoparticle confined within a cross-linked collapsed polyelectrolyte polymer wherein the nanoparticle comprises a charged organic ion.
US08283035B2 Process for obtaining rubber pellets from used tyres
A process for obtaining rubber pellets from used tires is described, the process comprises a series of steps which take account of the structure of a tire, and among which are mainly: collecting used tires having a tread and lateral faces, in which the tread includes an inner layer and an outer layer; and each lateral face includes a flange at the inner edge thereof; separating the tread from the lateral faces; cutting the tread transversely through the inner layer and the outer layer in order to form a strip from the tread; cutting the strip in order to form pellets therefrom; detaching the flange from the separated lateral faces; and cutting the flange-less lateral faces in order to form pellets therefrom.
US08283034B2 Process for producing a nanoscale zero-valent metal
This invention describes a process for producing a nanoscale zero-valent metal, including reduction of a metal ion solution with a dithionite compound, wherein the reduction is carried out under alkaline conditions under substantially an inert atmosphere. A nanoscale zero-valent metal obtainable by this process, and having a new crystalline form, is also described. The nanoscale zero-valent metal produced by the process of the invention is preferably iron, and is advantageously used for the remediation of contaminated water.
US08283030B1 Polymer mechanical damping composites and methods of production
A method of reshaping an article comprising a polyelectrolyte complex, the polyelectrolyte complex comprising an intermolecular blend of a predominantly positively-charged polyelectrolyte and a predominantly negatively charged polyelectrolyte by controlling the salt doping level.
US08283025B2 Reinforced silicone resin films
Reinforced silicone resin films comprising at least two polymer layers, wherein at least one of the polymer layers comprises a cured product of a at least one silicone resin having an average of at least two silicon-bonded alkenyl groups or silicon-bonded hydrogen atoms per molecule, and at least one of the polymer layers comprises a carbon nanomaterial.
US08283024B2 Laminate for protecting metals from corrosive gases
A corrosive gas resistant laminate comprises an outer polymer layer desirably containing a volatile corrosion inhibitor therein, a corrosion gas resistant barrier layer that can be a hydrophilic polymer, and a tie layer located between said outer and said barrier layers. The various laminates have improved transmission resistance with regard to corrosive gases such as oxygen, hydrogen sulfide, and halogen gases such as chlorine. The laminates can be used to protect metal during storage and transit.
US08283023B2 Asymmetrical flexible edge seal for vacuum insulating glass
A flexible edge seal for a vacuum insulating glazing unit. The flexible edge seal comprises an elongate first edge seal portion having a substantially constant first cross-section and including a bonding flange at one end, a weld surface at the other end and a first center portion therebetween. An elongate second edge seal portion has a substantially constant second cross-section and includes a bonding flange at one end, a weld surface at the other end and a second center portion therebetween. Each bonding flange includes a substantially flat portion adapted for hermetic bonding to a surface of a different one of a pair of glass panes. The weld surfaces are hermetically joined to one another forming a hermetic seal therebetween. At least one of the first center portion and the second center portion has a convolute cross-section and is asymmetrical to the other center portion.
US08283018B2 Composite structure
A composite structure comprising: a panel formed from two or more plies of composite material, the panel having a surface formed with a step where the thickness of the panel changes. Two or more stiffeners are attached to the surface of the panel. One of the stiffeners engages at least part of the step so as to transmit load forces in the panel.
US08283016B2 Artificial grass fibre and artificial lawn thereof
The invention relates to an artificial grass fiber in particular for use in an artificial mat for an artificial lawn, which artificial grass fiber is made of at least one synthetic material. The invention also relates to an artificial mat, in particular for use in an artificial grass sports field, which artificial mat is built up of a carrier to which at least artificial grass fibers according to the invention are attached. The object of the invention is therefore to provide an improved artificial grass fiber which on the one hand can be produced by means of the existing techniques and which on the other hand reduces the number of injuries on the field. According to the invention, the artificial grass fiber to that end furthermore comprises at least one additional material component, which additional material component imposes a permanent volume increase on the artificial grass fiber under the influence of an external stimulus after the artificial mat has been provided with the artificial grass fiber. Thus it is possible to create an artificial mat for a lawn, which can be produced by means of the standard production techniques and wherein the artificial grass fiber in question foams and transforms into, for example, a dampening layer after the manufacture of the artificial lawn, which layer improves or influences the playing characteristics of the sports field, such as the absorption of shocks, the restition of energy, the vetical deformation, grip and ball bounce and which furthermore reduces the number of player injuries.
US08283014B2 Optical recording medium
Disclosed herein is an optical recording medium, including: a substrate; and an information recording layer formed on the substrate, an information signal being recorded and reproduced in and from the information recording layer by radiation of a light; wherein the information recording layer includes a reflecting layer, a dielectric layer formed on the reflecting layer, and a recording layer formed on the dielectric layer, the dielectric layer includes a first dielectric layer and a second dielectric layer, and a thermal conductivity of the second dielectric layer located on the reflecting layer side is higher than that of the first dielectric layer located on the recording layer side.
US08283011B2 Easy-open reclosable films having interior frangible interface and articles made therefrom
The present invention relates to peelable resealable multilayer films which include at least a first polymer layer, a second polymer layer of pressure-sensitive adhesive in direct contact with and bonded to both the first and third layers. The bond formed between the second and third layers includes a peelable resealable interface having a first interfacial peel strength, A, and a second interfacial peel strength, B. The peelable resealable interface includes a first interfacial peel strength, A, having a value of less than 3500 gram-force/inch (1350 newton/meter) as measured in accordance with ASTM F-904-98 test method when the films of the present invention are peeled from a second thermoplastic film to which the film has been heat-sealed. The second interfacial peel strength, B, has a value of at least 400 gram-force/inch (154 newton/meter) as measured in accordance with ASTM F-904-98 test method when the films are peeled from and re-adhered to a second film.
US08283008B2 Container with tactile surface
A container having a surface including at least one high friction surface region having a coefficient of friction of between about 0.63 and about 2. Optionally, the at least one high friction surface region includes a coating layer, which may include fibers. The surface of the container may further include at least one low friction surface region having a coefficient of friction of less than 0.5, or preferably less than 0.3.
US08283007B2 Blow molded receptacle and system for making same
A system for making blow molded receptacles is disclosed generally comprising two mold portions that, when positioned adjacent each other, at least partially enclose a cavity defined by a molding surface, against which the walls of a blow molded receptacle are blown. One of the portions is a mold core, which has a base surface and a raised portion extending out from the base surface into the cavity. The raised portion has an outer surface and a side surface, which results in a corresponding, inner sidewall on the blow-molded receptacle. The raised portion houses a punch partly disposed in an opening in the side surface for punching a hole in the sidewall. In some embodiments, the side surface is substantially perpendicular to the seal between the two mold portions, and an actuator displaces the punch in a direction substantially parallel to the seam.
US08283006B2 Injection molding material containing starch and plant protein
An injection molding material that includes a renewable resin containing a combination of renewable polymers (e.g., starch and plant protein) and a plasticizer is provided. Although such compounds are normally difficult to process into thermoplastics, the present inventors have discovered that injection molding materials may nevertheless be formed by melt blending the renewable resin with a synthetic resin (e.g., polyolefin) while selectively controlling the nature of the resins and their relative concentrations. In this manner, a morphology may be achieved in which the renewable resin is present as a discontinuous phase that is dispersed within a continuous phase of the synthetic resin (e.g., “island-in-the-sea” morphology). The discontinuous and continuous phases may each constitute from about 30 vol. % to about 70 vol. %, and in some embodiments, from about 40 vol. % to about 60 vol. %. With such a morphology, the continuity of the synthetic resin can minimize the aggregate properties of the renewable resin such that the molding material possesses melt properties similar to that of the synthetic resin. Further, this morphology may also minimize the need to use different molding tools as the shrinkage properties of the overall composition may be substantially similar to that of the synthetic resin.
US08283003B2 Artificial turf
Artificial turf has a base layer, a multiplicity of blades fixed in and projecting upward from the base layer, and a mass of damping material on the base layer and through which the blades project. Each of the blades is at least partially formed of a polyester of terephthalic acid made from waste. The polyester is polyethylene terephthalate (PET) or polybutylene terephthalate (PBT), both from waste. The base layer is a flat primary layer, preferably a textile and preferably consists of plastic, a polyolefin and/or a polyester of terephthalic acid, preferably a polyester of terephthalic acid from waste.
US08283001B2 Liquid crystal compound and process for production thereof, liquid crystal composition, and liquid crystal electrooptical element
Disclosed is a liquid crystal composition suitable for producing a liquid crystal electrooptical element which can be driven at a low voltage in a wide temperature range and has high display quality. Also disclosed is a liquid crystal electrooptical element produced by using the liquid crystal composition. Further disclosed is a liquid crystal compound useful in preparing this composition.
US08282997B2 Method for producing a hydrophobic coating, device for implementing said method and support provided with a hydrophobic coating
The invention concerns a method for producing a coating on a support, in particular a glass support, wherein a thin-film metal oxide is deposited on the support, said thin film being subjected to an etching process to roughen its surface, a second coating capable of adhering to the first metal oxide film is then applied on the roughened surface. The invention is characterized in that it consists in depositing a first doped metal oxide or metal oxynitride doped with at least a second metal oxide or metal oxynitride, the second metal oxide or metal oxynitride being distributed in the deposited film. During the etching process, a plasma-activated gas is used which removes at least a second metal oxide or metal oxynitride less than the first metal oxide or metal oxynitride so as to form, after the etching process, on the surface raised irregularities consisting of at least a second metal oxide or metal oxynitride.
US08282991B2 Process for producing hydrophobized silicon oxide-coated metal oxide particles comprising primary and secondary hydrophobizing steps
Hydrophobized silicon oxide-coated metal oxide particles excellent in dispersibility in fluororesins, durability to fluorinated compounds and ultraviolet-shielding properties, and a fluororesin film excellent in transparency, weather resistance and ultraviolet-shielding properties comprising the hydrophobized silicon oxide-coated metal oxide particles, the hydrophobized silicon oxide-coated metal oxide particles being obtained by a process including a primary and a secondary hydrophobizing treatment.
US08282987B2 Aluminum-plated components of semiconductor material and methods of manufacturing the components
Aluminum-plated components of semiconductor material processing apparatuses are disclosed. The components include a substrate and an optional intermediate layer formed on at least one surface of the substrate. The intermediate layer includes at least one surface. An aluminum plating is formed on the substrate, or on the optional intermediate layer. The surface on which the aluminum plating is formed is electrically-conductive. An anodized layer can optionally be formed on the aluminum plating. The aluminum plating or optional the anodized layer comprises a process-exposed surface of the component. Semiconductor material processing apparatuses including one or more aluminum-plated components, methods of processing substrates, and methods of making the aluminum-plated components are also disclosed.
US08282986B2 Method of applying phosphor coatings
A method of applying a phosphor coating is described. The method comprises forming a suspension of a phosphor and a polymer binder dissolved in a solvent, the phosphor comprising at least one of a nitridosilicate or an oxonitridosilicate phosphor, the polymer binder being capable of decomposing thermally; applying the suspension to a substrate to form a coating; drying the coating; and baking the coating in an inert atmosphere to thermally decompose the polymer binder to form the phosphor coating, preferably at a temperature less than about 400° C. in a nitrogen atmosphere. A preferred polymer binder is polyisobutyl methacrylate
US08282976B2 Mixtures containing cocoa
The present invention relates to cocoa-containing powders with an isomaltulose fraction, in particular for producing instant ready-made beverages.
US08282975B2 Soft frozen liquid egg product
The present disclosure relates to a soft frozen liquid egg product including liquid egg, and at least one of incorporated air amount and at least one functional ingredient; wherein the soft frozen liquid egg product comprises a temperature ranging from about −25° F. to about 31° F. prior to heating. Methods of making the soft frozen liquid egg product are also disclosed. The soft frozen liquid egg product can be used to make various food products. Methods of making various food products comprising the disclosed soft frozen liquid egg product are also disclosed.
US08282972B2 Method and system for recovering and preparing glacial water
Methods and systems for grouping, recovering, and processing ice obtained from an ice source, i.e., a glacier, ice sheet, ice cap, etc., are described herein. In particular, the ice obtained from the ice source is separated and grouped according to common unique properties and processed as a beverage for consumption having the same unique properties.
US08282968B2 Bioactive water fraction from Gomphostemma niveum
The present invention relates to a novel bioactive water fraction obtained from the leaves of an herb named Gomphostema niveum commonly found in North Eastern part of India, and which is useful for inhibiting the growth of malarial parasite Plasmodium falciparum. The present invention also relates to a method for the extraction of said bioactive fraction. The present invention also provides methods for treatment of malaria using such bioactive water fractions and use of such bioactive water fractions for the treatment of malaria.
US08282966B2 Methods of reducing the risk of occurrence of pulmonary edema in children in need of treatment with inhaled nitric oxide
The invention relates methods of reducing the risk or preventing the occurrence of an adverse event (AE) or a serious adverse event (SAE) associated with a medical treatment comprising inhalation of nitric oxide.
US08282961B2 Method of preparing a microcapsule containing unsaturated fatty acids, the microcapsule prepared by the method, and articles containing the microcapsule
The present invention provides a preparing method of microcapsule containing unsaturated fatty acid comprising the steps of (a) preparing a first coating material by mixing and gelatinating one or more gums selected from the group consisting of xanthan gum, guar gum, and locusbean gum, with poly glycerin esters of fatty acid in sterilized water, adding unsaturated fatty acid to the solution, and homogenizing the solution; (b) preparing a second coating material by mixing and gelatinating starch or modified starch, gelatin or casein, and poly glycerin esters of fatty acid in sterilized water, adding the first coating material prepared in (a) to the solution, and homogenizing the solution; and (c) spraying the second coating material prepared in (b) in cold sterilized water; a microcapsule prepared by the method; and articles containing the microcapsule.The present microcapsule has effects of preventing the oxidation of unsaturated fatty acid and inhibiting offensive smell.
US08282955B2 Method for the preparation of a pharmaceutical composition comprising 5-aminosalicylic acid for use in treatment of ulcerative colitis and Crohn's disease
The present invention concerns a new method of preparing granules comprising 5-aminosalicylic acid and a new method of preparing a pharmaceutical composition for the treatment of ulcerative colitis or Crohn's disease by oral administration comprising as active ingredient 5-aminosalicylic acid.
US08282952B2 Insect attractant
The invention relates to insect attractants containing compounds with pentagonal heterocyclic structures that are effective in attracting fruitflies.
US08282951B2 Antimicrobial coatings for treatment of surfaces in a building setting and method of applying same
Antimicrobial coatings to protect surfaces and a method of applying such a coating are disclosed. An antimicrobial coating may be applied to a surface, such as the interior surface of a building's exterior wall. The interior surface must be accessed, and then an antimicrobial coating is provided and applied. The antimicrobial coating includes an inorganic antimicrobial additive and a colloidal polymeric medium. The inorganic antimicrobial additive may be silver, platinum, gold, palladium, copper, zinc, boron, or a compound of any of those elements. By including an ultraviolet tracer or color dye additive in the coating, it is possible to detect the coating at any time, provided that the surface is accessed.
US08282946B2 Water-soluble ginger root extract
Provided are a water-soluble ginger root extract which is a water extract or a hydrous alcohol extract of a ginger root and is substantially free of gingerols; and a hair growth inhibitor and a preparation for external use each containing the extract. The water-soluble ginger root extract of the present invention causes less skin irritation because of being substantially free of gingerols, and has excellent body-hair growth inhibiting effects, so that it is useful as a hair grown inhibitor and a preparation for external use, each having a high degree of safety.
US08282943B2 Therapeutic composition for use in the prevention and treatment of bone metastases
The invention is relates to drugs on the basis of antibodies against non-cellular bone matrix proteins, especially BSP, for use in the prevention and treatment of bone metastases. According to the invention, the antibodies are induced in the patient by recombinantly expressing antigenic determinants of bone matrix proteins in Listeria and anchoring them on the surfaces thereof. The antigenic determinants are selected according to whether they are characteristic of antigens that are expressed by the tumor cells themselves.
US08282942B2 Toxoplasma gondii vaccines and uses thereof
The present invention provides attenuated Toxoplasma gondii knockout mutants of the de novo pyrimidine synthesis pathway and use of the same in vaccines and methods of providing an immune response and protecting a subject against infection by T. gondii and a non-T. gondii disease.
US08282941B2 Immunizing compositions and methods of use
The present invention provides compositions including siderophore receptor polypeptides from gram negative microbes, and preferably, lipopolysaccarhide at a concentration of no greater than about 10.0 endotoxin units per milliliter. The present invention also provides methods of making and methods of using such compositions.
US08282939B2 Attenuated live triple G protein recombinant rabies virus vaccine for pre- and post-exposure prophylaxis of rabies
The invention provides a recombinant rabies viruses comprising three copies of a mutated G gene wherein each G gene encodes a rabies virus glycoprotein having the amino acid 194 mutated to a serine and the amino acid 333 is mutated to a glutamic acid. The recombinant rabies virus is nonpathogenic in immunodeficient mammals and can be used in a vaccine to induce an immune response protect mammals from infection by rabies virus as well as clear a pre-existing rabies virus infection from neural tissues.
US08282938B2 Immunogenic compositions comprising liposomes and an influenza PB2 CTL epitope obtained from the highly pathogenic H5N1 strain
The present invention provides an avian influenza vaccine containing a peptide-bound liposome wherein; the peptide contains: (1) an amino acid sequence shown by any one of SEQ ID NO:1 to 9, or (2) an amino acid sequence shown by any one of SEQ ID NO:1 to 9 wherein one or two amino acids are substituted, has a length of 9 to 11 amino acids, and is capable of inducing HLA-restricted cytotoxic T lymphocytes; wherein the liposome contains a phospholipid having an acyl group with 14 to 24 carbon atoms and one unsaturated bond or a hydrocarbon group with 14 to 24 carbon atoms and one unsaturated bond, and a liposome stabilizer; and wherein the peptide is bound to the surface of the liposome.
US08282933B2 P. gingivalis antigenic composition
The present invention provides an antigenic composition, the composition comprising at least one recombinant protein. The recombinant protein comprises at least one epitope. The epitope is reactive with an antibody which is reactive with a polypeptide having the sequence set out in SEQ. ID. NO. 3 or SEQ. ID. NO. 5. The invention also provides methods and compositions for the production of the recombinant protein. Also provided are methods for the diagnosis, treatment and prevention of P. gingivalis infection.
US08282932B2 Split-core-particles for the presentation of foreign molecules, especially for vaccine applications, and method for their production
Disclosed are split-core carrier substance which, as separate polypeptide, have the core N domain and the core C domain of the core protein of a hepatitis B virus and at least one foreign molecule against which an immune response is to be induced. According to the invention, the foreign molecule, especially the heterologous foreign amino acid sequence, is fused to the C terminus or the core N domain or to the N terminus of the core C domain and the core protein can form capsid-like particles. The invention also relates to the associated production method.
US08282931B2 Vascular endothelial growth factor C (VEGF-C) protein and gene, mutants thereof, and uses thereof
Provided are purified and isolated VEGF-C polypeptides capable of binding to at least one of KDR receptor tyrosine kinase (VEGFR-2) and Flt4 receptor tyrosine kinase (VEGFR-3); analogs of such peptides that have VEGF-C-like or VEGF-like biological activities or that are VEGF or VEGF-C inhibitors; polynucleotides encoding the polypeptides; vectors and host cells that embody the polynucleotides; pharmaceutical compositions and diagnostic reagents comprising the polypeptides; and methods of making and using the polypeptides. Methods of inhibiting endothelial cell proliferation are also provided.
US08282927B2 Immunoglobulin fraction and process therefor
The invention relates to the production of compositions containing IgA for use as a food additive. More specifically, it relates to a process to prepare an IgA-enriched milk product extract composition and to such compositions.
US08282921B2 tRNA synthetase fragments
The present invention relates to compositions and methods for treating conditions associated with angiogenesis. In particular the present invention relates to multi-unit complexes of tRNA synthetase fragments and uses thereof; diverse multi-unit complexes including a tRNA synthetase fragment; compositions and methods for modulating angiogenesis; polynucleotides encoding tRNA synthetase fragments and uses thereof; antibodies and epitopes specific to tRNA synthetase fragments; variants of tRNA synthetase fragments and uses thereof; methods for treating angiogenesis; methods for screening for anti-angiogenic agents; methods of modulating angiogenesis; kits for modulating angiogenesis; and business methods for modulating angiogenesis. Preferably the tRNA synthetase fragments are tryptophanyl tRNA synthetase fragments, and more preferably human tryptophanyl tRNA synthetase fragments.
US08282919B2 Microorganism strain CRC2631 of Salmonella typhimurium and its use as a cancer therapeutic
The present invention provides a biologically pure isolate of the genus Salmonella having a disruption of at least one gene selected from the group consisting of aroA, rfaH, and thyA, as well as a method of treating cancer including the step of administering such a Salmonella to a subject in need thereof.
US08282918B2 Polynucleotides encoding RPA4/RPA32 hybrid polypeptides
Disclosed are polynucleotides and polypeptides that are useful for assessing and modulating cell proliferation. The polynucleotides may comprise coding regions for RPA4 and RPA4/RPA32 hybrid polypeptides. The polynucleotides may be used in gene vectors for modulating cell proliferation in a patient in need thereof. Diagnostic methods related to assaying RPA4 expression in test samples in order to detect proliferating or cancerous cells also are disclosed.
US08282913B2 Ion binding polymers and uses thereof
The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides compositions comprising potassium binding polymers and pharmaceutical compositions thereof. Methods of use of the polymeric and pharmaceutical compositions for therapeutic and/or prophylactic benefits are disclosed herein. Examples of these methods include the treatment of hyperkalemia, such as hyperkalemia caused by renal failure and/or the use of hyperkalemia causing drugs.
US08282910B2 Composition for skin or hair
The present invention provides a composition for skin or hair which achieves an excellent UV absorption in a wide range of UV wavelength from the UV-A to the UV-B without inhibiting the effect of the alkyl β,β-diphenylacrylate and the α-cyano-β,β-diphenylacrylate (e.g. octocrylene) which serve to improve the photostability of dibenzoylmethane derivative. The composition for skin or hair comprises: (a) a dibenzoylmethane derivative, (b) an alkyl β,β-diphenylacrylate and/or an α-cyano-β,β-diphenylacrylate (e.g. octocrylene), and (c) a specific benzalmalonate derivative (e.g. di(2-ethylhexyl)-4-methoxybenzalmalonate).
US08282909B2 Pharmaceutical composition for topical application of poorly soluble compounds
The present invention provides a formulation which contains a poorly water soluble pharmaceutically active compound at a concentration of 50 mg per 100 g formulation or above. The solubility is achieved by a mixture of solvents as described herein. Moreover the formulation as described herein may be used as a base formulation to generate a cream, an ointment, a spray, a foam or an oleogel.
US08282908B2 Zeolite beta and process for producing the same
A zeolite beta according to the present invention has a SiO2/Al2O3 ratio of 10 to 16 and is aluminum-rich. The zeolite beta has a BET specific surface area measured in the state of a sodium type of 500 to 700 m2/g, a micropore specific surface area of 350 to 500 m2/g, and a micropore volume of 0.15 to 0.25 cm3/g.
US08282906B2 Remote plasma synthesis of metal oxide nanoparticles
A method of synthesizing nanoparticles, comprising providing a precursor comprising a titanium alkoxide compound; forming a plasma from oxygen gas at a first location, wherein the plasma comprises plasma products that contain oxygen atoms; causing the plasma products to flow to a second location remote from the first location; contacting the precursor with the plasma products at the second location so as to oxidize the precursor and form nanoparticles; and collecting the nanoparticles with a collector.
US08282905B2 Fullerenic structures and such structures tethered to carbon materials
The fullerenic structures include fullerenes having molecular weights less than that of C60 with the exception of C36 and fullerenes having molecular weights greater than C60. Examples include fullerenes C50, C58, C130, and C176. Fullerenic structure chemically bonded to a carbon surface is also disclosed along with a method for tethering fullerenes to a carbon material. The method includes adding functionalized fullerene to a liquid suspension containing carbon material, drying the suspension to produce a powder, and heat treating the powder.
US08282904B2 Cylindrical vessel made of carbon and process for making silicon
A cylindrical vessel made of carbon is used in the production of silicon. The inner surface of the vessel comes into contact with a silicon melt, wherein the permeation with silicon melt is reduced, formation of SiC is suppressed, and the vessel is resistant to deformation even when volumetric expansion ascribable to silicon is brought about. The carbon-made cylindrical vessel is made of a carbon material having a bulk specific gravity of 1.8 or more. The thermal expansion coefficient of the carbon material at 350 to 450° C. is preferably 3.5×10−6/° C. to 6.0×10−6/° C. A process for producing silicon uses said vessel wherein a chlorosilane is reacted with hydrogen.
US08282900B2 Agent for rendering halogen-containing gas harmless, and method of rendering halogen-containing gas harmless using same
An agent for rendering harmless a halogen-containing gas such as a halogen-containing exhaust gas, which comprises a faujasite zeolite having a SiO2/Al2O3 ratio of 2.0 to 2.3 and containing at least one cation selected from alkali metal cations and alkaline earth metal cations. The cation is preferably selected from Na and K, and, more preferably, the cation comprises at least 70 mol % of Na and not larger than 30 mol % of K. The agent is used in the form of a molded body made using a binder.
US08282898B2 Process for the formulation of potassium chloride from a carnallite source
A process for formulating high purity potassium chloride from a carnallite source. The process takes advantage of solubility differences and saturation levels in a multiple salt system generated upon dissolution of carnallite. In the system, the sodium chloride is kept in solution and the magnesium chloride present in the system is controlled to be in a concentration range of between 12% and 25% by weight. This avoids co-precipitation of sodium chloride with the potassium chloride during crystallization and therefore prevents the sodium chloride from contaminating the potassium chloride. The result is high grade potassium chloride.
US08282896B2 Devices and methods for holding microfluidic devices
Carriers or holders for holding microfluidic devices are provided. Some of the carriers that are provided include a hydration control device and/or a source of controlled fluid pressure to facilitate use of the carrier in conducting various types of analyses.
US08282895B2 Reagent cabinet system
A reagent cabinet for an automated processing apparatus. The reagent cabinet has a housing, and a drawer slidably mounted in the housing. The drawer has a lower deck adapted to receive a fluid reservoir, and an upper deck located above the lower deck and adapted to receive a fluid supply container. A supply connection hose is provided to selectively connect the fluid supply container to the fluid reservoir. A reservoir connection hose is provided to selectively connect to the fluid reservoir and to convey fluid from the fluid reservoir to a downstream location outside the cabinet. A pump is mounted on the drawer. The pump is adapted to convey fluid through either the supply connection hose or the reservoir connection hose.
US08282891B2 Apparatus for the generation of gases
The instant application provides apparatus and methods for the generation of gas, preferably chlorine dioxide. The methods and apparatus of the invention use a removable reaction chamber for the reaction of precursor chemicals, e.g., chlorite salt and an acid. The methods and compositions of the invention provide gas for a number of personal and commercial applications.
US08282889B2 Decomposing system for polyisocyanate residues, and start-up method for the same
An object of the invention is to provide a decomposing system for polyisocyanate residues that is capable of suppressing reaction of polyisocyanate residues with high temperature and high pressure water to allow smooth start-up of the operation, and a start-up method for the decomposing system for the polyisocyanate residues. The decomposing system is used for hydrolyzing the polyisocyanate residues to polyamine using high temperature and high pressure water, comprising a hydrolyzer, a water feed pipe connected to the hydrolyzer, a residual feed pipe connected to the water feed pipe, a solvent feed line for filling an organic solvent in a solvent filling portion of the residual feed pipe, and a solvent draining line. Upon start-up of the operation, the organic solvent is previously filled in the solvent filling portion via the solvent feed line and the solvent draining line, first, and then, the high temperature and high pressure water is fed from the water feed pipe to the hydrolyzer. Then, the organic solvent is fed from the residual feed pipe to the water feed pipe, first, and then, the polyisocyanate residues are fed thereto.
US08282888B2 Method and apparatus for the use of [11C] carbon monoxide in labeling synthesis by photo-initiated carbonylation
Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using amines and alkyl/aryl iodides are provided. The resultant carbon-isotope labeled amides are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.
US08282887B2 Multi-stage fluidized bed reactor for dehydrogenation of hydrocarbons
A reactor design and process for the dehydrogenation of hydrocarbons is presented. The reactor design includes a multibed catalytic reactor, where each of the reactor beds are fluidized. The catalyst in the reactor cascades through the reactor beds, with fresh catalyst input into the first reactor bed, and the spent catalyst withdrawn from the last reactor bed. The hydrocarbon feedstream is input to the reactor beds in a parallel formation, thereby decreasing the thermal residence time of the hydrocarbons when compared with a single bed fluidized reactor, or a series reactor scheme.
US08282886B2 Fluidized bed reactor with back-mixing for dehydrogenation of light paraffins
An improved process and system for the endothermic dehydrogenation of an alkane stream is described. The process and system for catalytic dehydrogenation comprise a back-mixed fluidized bed reactor. The alkane stream is dehydrogenated in a single reactor stage by contacting the alkane stream with a back-mixed fluidized bed of catalyst. Deactivated catalyst is withdrawn from the back-mixed fluidized reactor and heated to produce hot regenerated catalyst. The hot regenerated catalyst is returned to the back-mixed fluidized bed reactor at a rate sufficient to maintain the back-mixed fluidized bed reactor at substantially isothermal conditions.
US08282884B2 Reacting apparatus, method of assembling reacting apparatus and reactor containing package
A reacting apparatus includes a reactor having a supply port and a discharge port, a first member connected to the surface of the reactor having a through hole associated with the supply port, and a second member connected to the surface of the reactor and having a through hole associated with the discharge port, a supply pipe connected to the supply port by way of the through hole of the first member, to supply a fluid before the reaction to the supply port, and a discharge pipe connected to the discharge port by way of the through hole of the second member, to discharge a fluid after the reaction from the discharge port. The supply port and discharge port include a portion covered by a surface of the first member and a portion communicating with the through hole of the first member. The discharge port includes a portion covered by a surface of the second member and a portion communicating with the through hole of the second member. A first opening of the through hole of the first member includes a portion covered by the surface of the reactor and a portion communicating with the supply port. A second opening of the through hole of the second member includes a portion covered by the surface of the reactor and a portion communicating with the discharge port.
US08282883B2 Blower type chemical diffusing apparatus with fuel cell power supply
A blower type chemical diffusing apparatus is disclosed which can be of service for an extended period of time and does not give rise to refuse disposal problems. The blower type chemical diffusing apparatus of the invention has an air blower, a chemical retainer and a fuel cell included in the apparatus body whereby powering the air blower to drive it with the fuel cell causes chemical from the chemical retainer to be emitted into an environmental atmosphere.
US08282881B2 Analyte treatment apparatus
An analyte treatment apparatus comprising liquid chemical tanks storing liquid chemicals; and a treatment unit carrying out a treatment by supplying the liquid chemicals, so as to facilitate observation. The liquid chemical tanks are made of resin and housed inside a housing unit. Openings are formed in the housing unit. Light projecting means is provided outside of the treatment unit and projects light into each liquid chemical tank through the opening of the housing unit. A colored transparent door is provided to the housing unit and located at the other side with respect to a specific side of the liquid chemical tanks from which light diffusely reflected at the one side and the opposite side of the liquid chemical tank or in the liquid chemical tank can be visually checked, so as to visually check the reflected light. A control unit controls ON-OFF switching of the light projecting means.
US08282878B2 Sintering aids
Embodiments of the present invention disclosed herein include a sintering aid composition that has a material useful for sintering, an amine, and optionally a carboxylic acid.
US08282877B2 Process of making a hydroentangled product from cellulose fibers
The present invention relates to a process for the production of a hydroentangled product comprising cellulose fibers, which includes the steps of (a) extruding a solution comprising cellulose dissolved in an aqueous tertiary amine-oxide through a spinneret into an air gap, thereby forming filaments (b) drawing said filaments by means of a gaseous stream (c) collecting and precipitating said filaments in order to form a web (d) bonding said web by means of a hydroentanglement process (e) contacting said filaments in the air gap with a medium which at least partially coagulates the filaments. Furthermore, the invention relates to products obtainable by said products, and uses thereof.
US08282873B2 Controlled electrospinning of fibers
Methods for controlled electrospinning of polymer fibers are described. The methods include spinning a polymer fiber from a fluid comprising a polymer in the presence of an electric field established between a plurality of collectors and a jet supply device controlling the dispersion characteristics of the fluid by applying a magnetic field created by at least one magnet located after the point of jet formation. Different voltages are applied to at least two collectors of the plurality of collectors. At least one magnet, located between the jet supply device and at least one collector, creates a magnetic field substantially transverse or substantially collinear to an electrospinning jet stream. The magnetic field changes direction of travel of the electrospinning jet stream.
US08282869B2 Method for making precast concrete meter pit
A precast concrete meter pit consisting of a plurality of precast concrete hollow elongated cylindrical wall sections in end to end relation to one another is fabricated by utilizing a slip form packerhead apparatus in which the wall sections are formed with an annular slip ring when concrete is injected into the slip form apparatus.
US08282867B2 Insert molding die, insert molding apparatus and insert molding method
An insert molding die, an insert molding apparatus and an insert molding method are disclosed, wherein a pair of dies 10a, 10b are arranged in a manner capable of clamping, from axis X side, an insert part 2 arranged along axis X to be insert molded. The dies 10a, 10b include first separated dies 10a1, 10b1, second separated dies 10a2, 10b2 and third separated dies 10a3, 10b3 adapted to perform the clamp operation independently of each other.
US08282866B2 Method and device for forming three-dimensional model, sheet material processing method, and sheet material processing device
Three-dimensional models are produced using a sheet material made of water-soluble paper. Each layer of the sheet material is made severable along the contour lines of the three-dimensional model by discharging water onto each layer of the sheet material. A coloring solution is discharged when each layer is deposited to color the sheet material. After the deposition is completed, the unnecessary parts of the sheet material can be pulled away to complete the three-dimensional model. Alternatively, by discharging a setting solution onto each layer of the sheet material, each layer of the sheet material in the section of the three-dimensional model can be insolubilized, and a color setting solution can be discharged to color and set the colored parts. After the deposition is completed, the deposition can be immersed in water to remove the sheet material that was not insolubilized and complete the three-dimensional model.
US08282864B2 Water-resistant polarizing film, and process for producing the same
There is provided a water-resistant polarizing film including an organic dye having at least two anionic groups, and an alicyclic structure-containing compound having at least two nitrogen atoms in a molecule. Examples of the organic dye typically include an azo compound represented by the following general formula (2):
US08282863B2 High refractive index inorganic oxide nanoparticles comprising surface treatment, polymerizable resin, and articles
Microstructured films comprising surface modified inorganic oxide particles, surface modified inorganic nanoparticles having a high refractive index, and polymerizable resins are described.
US08282862B1 Triphenylmethane based complex dye, photosensitive resin composition for color filter including the same and color filter prepared using the same
A triphenylmethane-based complex dye, a photosensitive resin composition, and a color filter, the triphenylmethane-based complex dye being represented by the following Chemical Formula 1:
US08282859B2 Green emitting phosphor
A green emitting phosphor exhibiting an excellent absorption ratio is provided. A green emitting phosphor containing a crystal represented by MGa2S4:Eu2+, wherein M is an element comprising one species or a combination of two or more species among Sr, Ba and Ca, and Eu2+ is a luminescent center, and wherein the particle diameter at 10%, D10, 4.5 μm to 30 μm in the volume-based particle size distribution measured and obtained by the laser diffraction/diffusion particle size distribution measurement method.
US08282855B2 Composite positive active material of lithium battery and method for manufacturing the same
The composite positive active material of a lithium battery is composed of a main active material containing lithium and a sheathing active material containing lithium, whose particle diameter is far smaller than that of the main active material. A pulp containing these two active materials is sprayed and dried to form a mixed powder. The composite positive active material is obtained by means of sintering the mixed powder.
US08282854B2 (Li, Na, K)(Nb, Ta, Sb)O3 based piezoelectric material and manufacturing method thereof
A (Li, Na, K)(Nb, Ta, Sb)O3 based piezoelectric material is a sintered body having a surface microstructure that comprises microscopic grains having a grain diameter of less than 5 μm, intermediate grains having a grain diameter of 5 μm or more and less than 15 μm, and coarse grains having a grain diameter of 15 μm or more and 50 μm or less. The amount of coarse grains is 3% or more in a share of grains in terms of area. The piezoelectric material can be manufactured by mixing metal-containing compounds so as to give the above-mentioned formulation, calcining the mixture and then crushing the resultant to obtain a calcined/crushed powder, then keeping temperature constantly at a temperature within a range from 800 to 950° C. for a predetermined period of time in a constant temperature keeping process, and raising temperature to firing temperature for sintering.
US08282852B2 Magnetorheological fluid and method of making the same
A magnetorheological (MR) fluid is described herein. The MR fluid includes a plurality of magnetizable particles having a particle density. The fluid also includes a carrier fluid having a fluid density, and the plurality of magnetizable particles is dispersed within the carrier fluid. A portion of the plurality of magnetizable particles has a particle density that is substantially the same as the fluid density. The MR fluid may include a plurality of magnetizable particles having an outer shell of a magnetizable material and a hollow core. The MR fluid may also include a plurality of magnetizable particles having an outer shell of a magnetizable material and a solid core. The MR fluid may include a plurality of magnetizable particles having a matrix and a plurality of sub-particles embedded therein. The core or matrix of these particles may include a ceramic, glass or polymer, or a combination thereof. The magnetizable material may include magnetizable metals, metal alloys and various ferrites, such as those comprising Co, Fe, Mg, Mn, Ni, or Zn, or a combination thereof.
US08282851B2 Anisotropic cellular elastomers
The invention relates to a cellular elastomer which is anisotropic, with anisotropy being defined by the compressive modulus in one of three orthogonal directions being greater than that in the other two directions by a factor of at least 1.5. The invention also relates to a cellular elastomer containing magnetizable particles which have a chain-like alignment along one spatial direction. The invention also relates to a process for producing a cellular elastomer containing magnetiable particles and the use of such elastomers in articles of manufacture.
US08282846B2 Metal interconnect structure with a side wall spacer that protects an ARC layer and a bond pad from corrosion and method of forming the metal interconnect structure
A metal interconnect structure, which includes a bond pad, an overlying anti-reflective coating layer, an overlying passivation layer, and an opening that exposes a top surface of the bond pad, eliminates corrosion resulting from the anti-reflective layer being exposed to moisture during reliability testing by utilizing a side wall spacer in the opening that touches the side wall of the passivation layer, the side wall of the anti-reflective coating layer, and the top surface of the bond pad.
US08282843B2 Method for manufacturing perpendicular magnetic head including a main pole surrounded by shield layers
A method of manufacturing a perpendicular magnetic head having a writing element that writes magnetic information to a recording medium includes forming a main magnetic pole part generating a magnetic field on a substrate; removing at least a part of the substrate and a material existing at a circumference of the main magnetic pole part to expose an entire circumference of the main magnetic pole part at a surface that becomes an opposing medium surface (ABS) opposite to the recording medium; forming a shield gap film that is made of a nonmagnetic material so as to cover the entire circumference of the main magnetic pole part at least at the surface that becomes the ABS; and forming a shield layer so as to cover an entire circumference of the shield gap film at least at the surface that becomes the ABS.
US08282842B2 Cleaning method following opening etch
A cleaning method following an opening etching is provided. First, a semiconductor substrate having a dielectric layer is provided. The hard mask layer includes at least a metal layer. The opening etch is then carried out to form at least an opening in the dielectric layer. A nitrogen (N2) treatment process is performed to clean polymer residues having carbon-fluorine (C—F) bonds remained in the opening. Finally, a wet cleaning process is performed.
US08282841B2 Printed circuit board and manufacturing method thereof
A printed circuit board includes a flexible insulated substrate with a first surface and a second surface at both sides respectively, a wiring layer on the first surface, a reinforcement plate on a part of the second surface and an auxiliary layer between the second surface and the reinforcement plate. A reinforcement edge side of the reinforcement plate is located at the outside of an auxiliary edge side of the auxiliary layer.
US08282838B2 Method and apparatus for separating and removing fluids from drill cuttings
A method and apparatus is provided for removing fluids, particularly entrained and/or adherent fluids, from drill cuttings created during the well drilling process. An apron assembly collects drill cuttings and deposits such cuttings on a central rotor having multiple distinct chambers. A first chamber is loaded with drill cuttings. The central rotor thereafter cycles to a second position wherein a pressure seal is formed around the loaded first chamber. An air knife or similar device is used to blast compressed gas at the cuttings in the sealed chamber and force the cuttings against a screen. Solid components of the cuttings remain in the sealed chamber, while liquid components pass through the screen and are collected using an auger assembly. Following such separation, the rotor is cycled again, allowing dried cuttings to empty from the first chamber. The process is repeated for each chamber of the rotor.
US08282836B2 Water intake structure
Water intake structures for power plants and other industrial facilities may include an inflow channel, a deep well, an outflow channel, and an intake channel These structures may include a fish screen, such as a wedge-wire screen or the like, positioned between the deep well and the intake channel to separate fish, fish larvae and fish eggs from water supplied to the intake channel from the deep well. These structures may further include one or more circulating or sweep flow pumps positioned proximate an outlet of the outflow channel. The sweep flow pumps may be used to maintain a sweep flow through the deep well of the intake structure to help sweep fish, fish larvae and fish eggs away from the fish screen and into the outflow channel.
US08282835B2 Removal of selenium from refinery wastewater
The invention provides a method of efficiently removing selenium from water. The method involves: adding an oxidant to the liquid, adjusting the liquid's pH to below 7.5, adding ferric salt in an amount such that less than a quarter of selenium in the liquid precipitates and adding a poly dithiocarbamate material to the liquid in an amount such that the amount of poly dithiocarbamate material (in ppm) is greater than the amount of ferric salt (in ppm). This method removes far more selenium than previous methods, and does it using a smaller amount of expensive chemicals. Moreover this method makes it far more likely to achieve cost effective compliance with the ever-increasing environmental standards for selenium in water.
US08282834B2 Di- and mono-alkoxysilane functionalized polymers and their application in the Bayer process
Dialkoxysilane and Monoalkoxysilane functionalized polymers were applied as scale control agents in Bayer process. The polymer inhibitors reduced the quantity of aluminum silicate scale formed in spent liquor while significantly changed the morphology of the scale. Also a method is provided for reducing aluminum silicate scale of Bayer process by adding the dialkoxysilane and monoalkoxysilane functionalized polymer into the Bayer liquor stream.
US08282830B2 Method, apparatus, and processes for producing potable water utilizing reverse osmosis at ocean depth in combination with shipboard moisture dehumidification
Devices and methods for producing purified water. The device includes a reverse osmosis subsystem, a dehumidification subsystem and a purified water storage tank fluidly coupled to the subsystems such that purified water produced by each can be locally stored. A vehicular platform, such as a ship, can be used to locate the device adjacent a supply of saline water and humid air. A saline water inlet, membrane and purified water outlet cooperate in the reverse osmosis subsystem to allow preferential passage of water relative to salt in a saline water supply, while the dehumidification subsystem includes a heat exchanger that extracts moisture from the ambient humid air. Purified water produced by each of the subsystems can be used as a potable water source. When used in conjunction with a ship, part or all of the reverse osmosis subsystem can be submersed to a depth sufficient to generate a hydrostatic pressure that is in turn sufficient to passively operate the reverse osmosis membrane such that additional pressurizing equipment, such as a pump, is not needed. Furthermore, the temperature of the water purified by the reverse osmosis subsystem may be low enough to be used as a condensing agent for the ambient humid air passing through the dehumidification subsystem.
US08282826B1 Bacterial cultivation system for growth of substrate specific micro-organisms for use in industrial wastewater remediation
A waste treatment method includes the concentration of selected strains of bacteria in a selected medium in the presence of nutrients and water, under aerobic conditions. This concentrated batch is discharged for downstream applications in wastewater remediation. A cultivation chamber having inlet ports and a circular vent port allows for adequate air introduction and heat release. Aeration is achieved by recirculation of the fluid medium from the top of the apparatus through a pipe that runs the length of the inner wall and is specially configured at the top to minimize cell damage. Fluid can be routed tangentially in clockwise and counterclockwise directions. The conical bottom has an orifice allowing for recirculation of the fluid medium tangentially to the sidewalls. Upon completion of the batch cultivation, the medium and bacteria are discharged for downstream applications in wastewater remediation of paper mill, chemical plant, oil refinery, and other industrial effluents.
US08282822B2 Membrane cartridge in immersion type membrane separation apparatus
A membrane cartridge in an immersion type membrane separation apparatus capable of suppressing vibrations applied to the membrane cartridge by an ascending force of membrane cleaning gas and others by firmly coupling the adjacent membrane cartridges disposed in parallel. In a membrane cartridge in an immersion type membrane separation apparatus, selvages larger in thickness than a membrane cartridge main body are formed at both sides of the membrane cartridge, and a header forming part is formed on one selvage, and a guide hole is formed in other selvage relatively, and the header forming part and the guide hole of the membrane cartridge disposed adjacently by varying the direction mutually are formed to communicate and connect with each other.
US08282820B2 Water filter for refrigerator water dispenser
A water dispenser in a refrigerator door can include a filter casing in the door opening into the bottom of the dispenser housing. The filter casing can include a top wall positioned in the bottom of the dispenser housing, a head assembly at the bottom of the filter casing connected to the water supply and to a water outlet in the dispenser, and can include a filter casing drain. A filter cartridge in the filter casing can connect to the head assembly. The filter casing can include a filter retainer mounted adjacent the opening into the filter casing and can hold the filter cartridge connected to the head assembly in a first position and can release the filter cartridge in a second position. The filter casing can include a drain line leading from the filter casing drain to a pan outside the refrigerated space.
US08282819B2 Filter device with a heater
Disclosed is a filter device (10), particularly a liquid filter, comprising a filter element (16) that is disposed in a filter housing (12, 14) and a heater (28) for heating medium flowing through the filter device (10). The inventive filter device (10) is characterized in that the heater (28) is designed with at least one heating circuit (30) that is molded into the filter housing (12, 14). Alternatively or additionally, the heater (28) is designed with at least one heating circuit (30) which is provided with an electrical contact (34) in at least one of the final zones thereof, said electrical contact (34) being riveted to the heating circuit (28).
US08282817B1 Septic system
A system and method includes an aeration subsystem that excites enzymes in the liquid waste passing through the septic system. The aeration subsystem includes a compressor section that compresses the liquid waste and an injector section that injects oxygen into the compressed liquid waste. The system further includes a driver subsystem for driving the compressor section and a control subsystem for activating and deactivating the driver subsystem.
US08282809B2 Method and apparatus for ammonia (NH3) generation
Various apparatuses and methods for producing ammonia are provided. One embodiment uses a plurality of environments and an electrode configured to be exposed to the plurality of environments. The electrode is configured to receive hydrogen while being exposed to one of the environments, reduce nitrogen while being exposed to another environment, and allow the hydrogen and nitrogen to react with each other to form ammonia. Other embodiments provide for simultaneous hydrogen oxidation and nitrogen reduction at the same electrode, which in turn react for formation of ammonia.
US08282808B2 Use of phosphinic acids and/or phosphonic acids in redox processes
The present invention relates to the use of phosphinic acids and/or phosphonic acids and salts thereof, preferably as surface-active compounds, in redox processes, in particular in electroplating technology, particularly preferably in electroplating baths, and to electroplating baths comprising these compounds.
US08282801B2 Methods for passivating a metal substrate and related coated metal substrates
Disclosed are methods for passivating metal substrates, including ferrous substrates, such as cold rolled steel and electrogalvanized steel. The methods comprise the steps of depositing an electropositive metal onto at least a portion of the substrate, followed immediately by electrophoretically depositing on the substrate a curable, electrodepositable coating composition. The present invention also relates to coated substrates produced by the above methods.
US08282800B2 Hydrolysis-resistant polyacrylamide gels
Polyacrylamide gels that offer high resolution in protein separations and are more stable relative to hydrolysis than conventional polyacrylamide gels that rely on Tris or Tris-Bis as buffering agents are made by incorporating triethanolamine in place of most or all of the Tris or Tris-Bis.
US08282792B2 Process and system for the purification of trichlorosilane and silicon tetrachloride
The present disclosure relates to processes and systems for purifying technical grade trichlorosilane and/or technical grade silicon tetrachloride into electronic grade trichlorosilane and/or electronic grade silicon tetrachloride.
US08282791B2 Desalination using low-grade thermal energy
This invention describes a low temperature, self-sustainable desalination process operated under natural vacuum conditions created and maintained by barometric pressure head.
US08282784B2 Paper-making shoe-press belt
Provided is a paper-making machine belt (or a paper-making shoe-press belt), which is excellent in a wet-web water-squeezing property, which is stable in a paper quality (e.g., wet-web smoothness or marking property), and which has little damage (e.g., cracking or wear) of the outer circumference of the belt being used. The paper-making shoe-press belt carries a felt for accepting the squeezed water from the wet-web and has draining grooves extended in the felt-side surface. The paper-making shoe-press belt is characterized in that the draining grooves extended in the felt-side surface have at least two kinds of different groove shapes in the transverse direction (or the CMD direction) of the paper-making machine. The groove shape enables the grooves of two continuous and discontinuous kinds to share the functions thereby to satisfy the improvements in the drainage and in the paper quality and the wet-web surface smoothness at the same time.
US08282782B2 Wet paper web transfer belt
A wet paper web transfer belt (1) has a wet paper web-side layer (31) including a resin and a hydrophilic fibrous body (30) and a machine-side layer (32). A basic fabric (33) disposed in the belt comprises a first woven fabric (34) disposed on a wet paper web (W) side and a second woven fabric (35) disposed on a press roll (10) side. The first woven fabric (34) and the second woven fabric (35) are stacked together. At least a portion of the hydrophilic fibrous body (30) is exposed on a surface (37) of the wet paper web-side layer (31). The basis weight of the first woven fabric (34) is greater than the basis weight of the second woven fabric (35). The structure is effective to improve a first function to cause the wet paper web (W) to stick thereon and to transfer the wet paper web (W), and a second function to allow the wet paper web (W) to be smoothly released from the belt for transferring the wet paper web (W) to a next process. The belt (1) has opposite edges (E) prevented from being curled while the belt (1) is traveling.
US08282777B2 Disposable wipers and towels containing 40% or more post-consumer waste
A high utility (strong in both dry and wet states, highly absorbent, abrasion resistant, thick, and soft) disposable wiper or towel that contains 40% or more cellulose fibers from post-consumer waste and/or in excess of 50% pre and/or post consumer waste. The base sheet is produced in a wet-pressed, creped process and is post-treated using a DRC process. The final wiper or towel is a double re-creped, non-woven sheet having a first side and a second side. The non-woven sheet includes about 85% to about 90% by weight of-cellulose fibers. The cellulose fibers include about 40% to about 80% of cellulose fibers from post-consumer waste. The non-woven sheet includes at least about 10% to about 15% by weight of binder. The wiper meets EPA guidelines related to the level of PCW in wipers.
US08282776B2 Wiping product having enhanced oil absorbency
Wiping products are disclosed containing an additive composition that enhances the cleaning properties of the product. The additive composition, for instance, comprises an aqueous dispersion containing an alpha-olefin polymer, an ethylene-carboxylic acid copolymer, or mixtures thereof. The alpha-olefin polymer may comprise an interpolymer of ethylene and octene, while the ethylene-carboxylic acid copolymer may comprise ethylene-acrylic acid copolymer. The additive composition may also contain a dispersing agent, such as a fatty acid. The additive composition increases various properties of the product including the ability of the product to quickly absorb oil. For instance, the additive composition can decrease the Oil Absorbency Rate by from about 20% to about 80% and can decrease the Reverse Osmosis Oil Wet Out time by from about 10% to about 80%.
US08282775B2 Web substrate having optimized emboss area
The present disclosure provides for a web substrate having at least one ply having a surface thereof. The surface of the at least one ply defines a surface area of the at least one ply. The surface comprises an emboss pattern disposed thereon. The emboss pattern has a surface area defined by a perimeter circumscribing the emboss pattern. The surface area of the emboss pattern ranges from about 5 percent to about 40 percent of the surface area of the at least one ply.
US08282774B2 Ligno cellulosic materials and the products made therefrom
A process comprising treating a lignocellulosic material preferably pulp in the presence of a transition metal catalyst with a oxidizing agent selected from a group consisting of hydrogen peroxide, hypochlorite, hypochlorous acid and any combination thereof to form a treated lignocellulosic material having a viscosity equal to or less than about 17 cp and having reducing functional groups selected from the group consisting of aldehyde and aldehyde type functional groups at the C6 and C1 positions but predominating at the C1 position.
US08282771B2 Method of processing a substrate, spin unit for supplying processing materials to a substrate, and apparatus for processing a substrate having the same
In a spin unit for rotating a substrate and a method of processing the substrate, the substrate is secured on a support and is rotated on the support. Processing materials including drying gases, etching solutions and cleaning solutions are selectively supplied onto a bottom surface of the rotating substrate. The same processing materials are also selectively supplied onto a top surface of the substrate. The top and bottom surfaces of the substrate are simultaneously processed by simultaneous supply of the processing materials through the first and second sub-injectors.
US08282767B2 Plasma processing apparatus
A plasma processing apparatus including a chamber having an inner wall with a protective film thereon and a sample stage disposed in the chamber in which plasma is generated by supplying high-frequency wave energy to processing gas to conduct plasma processing for a sample on the sample stage using the plasma. The apparatus includes a control device which determines, based on monitor values of a wafer attracting current monitor (Ip) to monitor a current supplied from a wafer attracting power source, an impedance monitor (Zp) to monitor plasma impedance viewed from a plasma generating power source, and an impedance monitor (Zb) to monitor a plasma impedance viewed from a bias power supply, presence or absence of occurrence of an associated one of abnormal discharge in inner parts, deterioration in insulation of an insulating film of a wafer attracting electrode, and abnormal injection in a gas injection plate.
US08282766B2 Etch apparatus and method of etching silicon nitride
An etch apparatus, especially for silicon nitride etch includes a control unit coupled to at least one component of the group of components comprising heater current sensors, a pump transducer sensor and a flow sensor provided for a diluting liquid. A malfunction of the apparatus is avoided and the etching process can be controlled for better performance.
US08282765B2 Adhesive sheet
The present invention provides an adhesive sheet for attaching to a plasticized vinyl chloride resin article such as a blood bag made of a plasticized vinyl chloride resin, and having a center-line surface roughness Ra of 1.0 μm or higher, which includes a film substrate and a heat-sensitive adhesive layer formed on a backside surface of the film substrate, wherein the heat-sensitive adhesive layer is composed of a resin containing a crystalline polyester resin as a main component. The adhesive sheet of the present invention is excellent in adhesive property when the adhesive sheet is attached to the article made of a plasticized vinyl chloride resin. The adhesive strength of the adhesive sheet of the present invention is not decreased even after an autoclave treatment or storage at a low temperature.
US08282764B2 Method for improving mechanical strength of bondings made with an adhesive based on curable resin by chain polymerization
The invention relates to a process that makes it possible to improve the mechanical strength of bonds between substrates when these bonds are produced by means of an adhesive that comprises a resin that can be cured by chain polymerization, and in particular a resin that can be cured under the effect of ionizing or light radiation.This process is characterized in that it comprises the grafting of groups capable of acting as chain transfer agents during the polymerization of said resin to the surface of the substrates, before the latter are brought into contact with the adhesive.Applications: assembling of structural, engine, passenger compartment or bodywork parts in the aeronautical, space, railway, ship-building and automotive industries.
US08282753B2 Articles and methods of masking or protecting a substrate
A protection sheet and method of protecting a substrate is disclosed. In an embodiment, the protection sheet comprises an adhesive coated nonwoven material. In an embodiment a surface of the protection sheet captures and retains paint overspray, dust, dirt and other contaminants so as to provide a cleaner paint job. In an embodiment the protection sheet may be laminated to a second nonwoven or woven material to allow clean removal after extended use. The protection sheet may be used to protect horizontal or vertical substrates, and is particularly suited to protect the surfaces of a paint booth used in automotive spray-painting operations.
US08282751B2 Methods of forming a sensitized explosive and a percussion primer
A sensitized explosive that comprises an explosive precipitated onto a sensitizer. The explosive is CL-20, PETN, RDX, HMX, or mixtures thereof and the sensitizer is aluminum, titanium, zirconium, magnesium, melamine, styrene, lithium aluminum hydride, or mixtures thereof. The sensitized explosive is used in a percussion primer that includes a bismuth compound and a melt binder. The bismuth compound is bismuth oxide, bismuth subnitrate, bismuth tetroxide, bismuth sulfide, or mixtures thereof and the melt binder is a wax having a melting point above ambient temperature, trinitrotoluene, poly(3,3-bis(azidomethyl)oxetane), poly(3-azidomethyl-3-methyloxetane), ethyl-3,5-dinitrobenzoate, or mixtures thereof. A gun cartridge and other primer-containing ordnance assemblies employing the percussion primer are also disclosed. Methods of forming the sensitized explosive and the percussion primer are also disclosed.
US08282750B1 Gas generant with auto-ignition function
Gas generating compositions include a combination of melamine and maleic hydrazide as a primary fuel; and a primary oxidizer consisting of ammonium nitrate and potassium chlorate. Gas generators and vehicle occupant protection systems incorporating the present compositions are also described.
US08282748B2 Process for producing metal matrix composite materials
The invention relates to a method for producing metal matrix composite materials, including at least one proportion of magnesium or one magnesium alloy and involving at least one production step in which a thixomolding ensues. According to the invention, an Mg2Si phase having a volume fraction of at least 2% is incorporated in a metal matrix preferably comprised of magnesium or of a magnesium alloy. The inventive method uses the thixomolding method for the in-situ production of a metallic composite material and is advantageous in that a broad range of adjustable volume fractions of the Mg2Si phase in the composite material results whereby enabling the properties of the composite material to be individually modified. The inventive metal matrix composite material is particularly suited for producing thermally stressed parts of motor vehicles such as pistons or the like.
US08282739B2 Preformed cigarette having a specifically defined immobilized flavorant additive insert positioned therein
Delivery of additives in a smoking article is provided through thermally degradable, robust immobilized additive inserts. Additives can be immobilized in an elongated device or an insert, wherein the elongated device or the insert is sufficiently robust to allow the elongated device or the insert to be manually or machine inserted into a smoking article while maintaining the structure of the elongated device or the insert. By providing additives in the form of thermally degradable immobilized additive inserts, migration and/or loss of the additives in a smoking article prior to smoking can be reduced.
US08282738B2 Solvo-thermal fractionation of biomass
The invention relates to a process for producing xylose and cellulose from a biomass comprising: (a) mixing a biomass with a reactive fluid comprising water and a supercritical C1-C5 alcohol to form a mixture at a first temperature and a first pressure; (b) maintaining the mixture at the first temperature and first pressure for a first time period, wherein a reaction occurs; and (c) quenching the reaction to form at least one reaction product mixture; wherein xylose and cellulose are produced by the process. Lignin may also be produced by the processes of the invention.
US08282736B2 Lower liner with integrated flow equalizer and improved conductance
A plasma processing chamber has a lower liner with an integrated flow equalizer. In an etching process, the processing gases may be unevenly drawn from the processing chamber which may cause an uneven etching of the substrate. The integrated flow equalizer is configured to equalize the flow of the processing gases evacuated from the chamber via the lower liner.
US08282731B2 Calcium sulfate hemihydrate treatment process
A process for treating beta calcium sulfate hemihydrate is disclosed. The process comprises exposing beta calcium sulfate hemihydrate to steam at a pressure above atmospheric pressure.
US08282727B2 Water-borne primer coating composition and method of forming coating film
A water-borne primer coating composition including a water-borne non-chlorinated polyolefin resin (A), a water-borne polyurethane resin (B), a water-borne epoxy resin (C) and an internally crosslinked acrylic particle emulsion (D), wherein the content of resin (A) is 15 to 60%, the content of resin (B) is 10 to 50%, the content of resin (C) is 20 to 50%, and the content of emulsion (D) is 5 to 20%, all by weight on the solid equivalent basis in 100% by weight of the total amount of resin (A), resin (B), resin (C) and emulsion (D), and resin (A) is a polypropylene resin having crystallinity of 35 to 55% and a weight average molecular weight of 50000 to 200000. The composition can achieve an adhesion property to a substrate, gasohol resistance, inhibition of peeling of a multilayer coating film in washing by high pressure cleaning and moisture resistance.
US08282725B2 Self-dispersion pigment, production process of self-dispersion pigment, ink set and ink jet recording method
The invention provides a self-dispersion pigment including a pigment, an ionic group directly bonded to the pigment and a nonionic molecular chain bonded to the pigment through an amide bond.
US08282724B2 Ink composition for inkjet printing by the continuous deflected jet technique
An ink composition for inkjet printing by the continuous deflected jet technique, which is liquid at ambient temperature, comprising: a) a binder; b) one or more dyes and/or pigments; and c) a solvent, in which: said solvent comprises at least 10% by weight—relative to the total weight of the ink composition—of at least one noncyclic acetal, and at least 5% by weight of one or more other organic compounds capable of dissociating the ionizable species that are found in the ink.
US08282723B2 Magenta inkjet ink having improved print quality with porous photo media
The present invention relates to magenta dye-based inkjet inks having improved permanence when jetted onto porous photo media. The inkjet ink includes a mixture of at least two magenta dyes, at least three co-solvents comprising about 18 to about 24% of the composition of the ink by weight, a penetrant, at least one wetting agent, and water.
US08282722B2 Gallium naphthalocyanine salts exhibiting reduced kogation
A sulfonated dye salt of formula (II): wherein M is Ga(A1); A1 is an axial ligand selected from the group consisting of: —OH and halogen; and Z1+, Z2+, Z3+ and Z4+ are independently selected from the group consisting of: H and an ammonium cation including 3 or more hydroxyl groups. At least one of Z1+, Z2+, Z3+ and Z4+ is the ammonium cation. Such salts exhibit reduced kogation in thermal bubble-forming inkjet printheads.
US08282718B2 Surface treatment solution, ink set, ink-jet recording method, and ink-jet recording apparatus
A surface treatment solution for a recording paper on which ink-jet recording is performed with a water-based ink, the surface treatment solution includes calcium alginate which is contained by 0.008 wt % to 0.074 wt % in the surface treatment solution, sodium alginate which is contained by 0.013 wt % to 0.084 wt % in the surface treatment solution, a water-soluble organic solvent, and water.
US08282716B2 Gas adsorbing device, vacuum heat insulator making use of gas adsorbing device and process for producing vacuum heat insulator
A jacket material into which a gas adsorbing device and core material are inserted is decompressed in a vacuum chamber, the opening is sealed, and then the jacket material is exposed to the atmosphere. In the atmospheric pressure, a pressure of about 1 atm which is equivalent to the pressure difference between the inside and outside is applied to the jacket material of the heat insulator. The jacket material is made of a plastic laminated film and is deformed by pressure. A protruding portion is plunged into a container to drill through holes, and a gas adsorbent in the container communicates with the inside of the jacket material. Thus, both during holding and in applying to the vacuum heat insulator, the gas adsorbent can be applied to the vacuum heat insulator without degradation, and the high degree of vacuum can be kept for a long time.
US08282714B2 Gas storage and dispensing system with monolithic carbon adsorbent
A pyrolyzed monolith carbon physical adsorbent that is characterized by at least one of the following characteristics: (a) a fill density measured for arsine gas at 25° C. and pressure of 650 torr that is greater than 400 grams arsine per liter of adsorbent; (b) at least 30% of overall porosity of the adsorbent including slit-shaped pores having a size in a range of from about 0.3 to about 0.72 nanometer, and at least 20% of the overall porosity including micropores of diameter<2 nanometers; and (c) having a bulk density of from about 0.80 to about 2.0 grams per cubic centimeter, preferably from 0.9 to 2.0 grams per cubic centimeter.
US08282711B2 Subsea installation and method for separation of liquid and gas
The present invention relates to a subsea installation for treatment of hydrocarbons from a subsea well, having a pipe system comprising a first manifold (2) connected to at least one well (1) and at least two first pipe segments (3) with an inlet connected to the manifold (2) and where the first pipe segments (3) comprise at least two outlets, where the first manifold (2) and the first pipe segments (3) are arranged in a first plane and where one of the outlets from the first pipe segments leads to a second manifold (7). According to the invention a second of the outlets from the first pipe segments (3) leads to at least two second pipe segments (9) arranged in a second plane and where at least one of the outlets forms an inlet to the second pipe segments (9), where the second pipe segments (9) comprise at least one outlet leading to a third manifold (12).
US08282709B2 Removal of ethane from natural gas at high pressure
ETS-10 type materials preferentially adsorb ethane and, if present, C3+ paraffins from mixtures comprising methane, ethane and optionally C3+ paraffins at pressures above 200 psia. A process in which ETS-10 type materials are used to separate ethane and C3+ paraffins from natural gas streams at over 200 psia is provided.
US08282708B2 Method of producing high purity steam
Methods for the purification of steam, systems for purifying steam, methods for measuring and/or controlling steam flow rates, and uses for purified steam are provide. Also provided are substantially gas-impermeable membranes, such as perfluorinated ionomers (e.g., perfluoroethylene-sulfonic-acid/tetrafluoroethylene membranes), having a high ratio of water vapor permeation relative to gas permeation through the membrane. Also provided are methods of operation of such membranes at relatively high operating temperatures for the purification of steam and for operation of such membranes at relatively low temperature and sub-atmospheric pressures for the purification of steam. In a preferred embodiment, the system 400 for purifying steam comprises heater 404 for creating a source of a steam feed, and a purification device 416 for housing a substantially gas-impermeable membrane 424. In the operation of system 400, water, such as deionized water, is added to vessel 402 to provide a source of the steam feed.
US08282698B2 Reduction of particle contamination produced by moving mechanisms in a process tool
In various exemplary embodiments described herein, a system and related method to reduce particle contamination on substrates is disclosed. The system includes a substrate traverser mechanism having tracks to transport substrate carriers with one or more traverser ducts arranged to surround, at least partially, the tracks. The one or more ducts have slits along at least a substantial portion of a length of the tracks. A traverser exhaust fan is coupled to one end of each of the one or more traverser ducts. The fan provides sufficient volumetric airflow such that a velocity of the volumetric airflow through the slits is greater than a terminal settling velocity of a predetermined particle size. The fan draws particles less than approximately the predetermined particle size generated by the substrate traverser mechanism into the one or more traverser ducts.
US08282694B2 Pretreatment of biomass feed for gasification
A pretreatment process of a biomass feedstock for gasification for the production of syngas. The biomass feed, which is preferably a cellulosic feed, is subjected to a two stage torrefaction that comminutes the biomass and increases its energy density.
US08282691B2 Cathode materials for secondary (rechargeable) lithium batteries
The invention relates to materials for use as electrodes in an alkali-ion secondary (rechargeable) battery, particularly a lithium-ion battery. The invention provides transition-metal compounds having the ordered-olivine or the rhombohedral NASICON structure and the polyanion (PO4)3− as at least one constituent for use as electrode material for alkali-ion rechargeable batteries.
US08282690B2 Process for the preparation of solar salt having high purity and whiteness
The process of the invention deals with significant improvements in salt purity and whiteness brought about through treatment of brine with alum prior to charging into crystallizers for solar salt production. The improvements realized are partly on account of elimination of suspended impurities like gypsum and clayey matter in the brine, which may otherwise be carried along with the brine in the crystallizer and finally end up in the salt, and partly due to the improved crystal size and morphology that minimizes embedded impurities in the salt. Rain washing of the heaped salt has resulted in a salt with greatly reduced calcium and sulphate impurity levels hitherto not achieved in solar salt production. Alum treatment by the process of the invention requires no additional time or infrastructure and the cost of the treatment works out to <3 U.S. cents per ton of salt. The process can be implemented in any solar salt works.
US08282689B2 Composition and method for enhancing the production of crystal agglomerates from a precipitation liquor
The present invention relates ways to increase the output of a high quality product from the precipitation liquor crystallization process exemplified through the aluminum hydroxide recovery processes such as the Bayer process. The invention is a method of increasing the size of precipitated of a liquor. The invention in one embodiment relates to the use of a crystal growth modifier compositions added to the precipitation process to increase the particle size distribution of the precipitated alumina trihydrate.
US08282688B2 Laccase mediators and methods of use
Novel laccase mediators, including carboxyamido and cyano derivatives of 2,6-dimethoxyphenol that exhibit improved hydrolytic stability and good bleaching performance. The novel laccase enzymes may be employed in conjunction with the 2,6-dimethoxyphenol derivatives of this invention to provide an improved method for bleaching denim fabrics.
US08282681B2 Bioresorbable spinal implant and related methods
A prosthesis for the replacement of an intervertebral disc of the spine comprises a block of an elastomeric material, which is held under compression by an encapsulating textile fabric. A preferred version of the invention has flanges that are continuations of the encapsulating fabric forming an interdigitation, with the continuation of the upper fabric passing through a hole in the lower fabric and being attached to the lower vertebral body and the continuation of the lower fabric crossing to its fixation site on the upper vertebral body. Optionally, the flanges are resorbable, over time leaving only the implant core and encapsulation fabric in the intervertebral space.
US08282679B2 Intravascular stents
Stent designs for use in vessels, such as the carotid and coronary arteries, are disclosed. The stents consist of a plurality of radially expandable cylindrical elements generally aligned on a common longitudinal stent axis and interconnected by one or more interconnecting members placed so that the stent is flexible in a longitudinal direction. The cylindrical elements form a generally serpentine wave pattern transverse to the longitudinal axis between alternating valley portions and peak portions. The interconnecting members are attached to the double-curved portions to connect a cylindrical element to an adjacent cylindrical element and interconnecting members are attached to the inverted double-curved portions to connect the cylindrical element to the other adjacent cylindrical element. The stent designs include both a six crown and an eight crown stent which exhibit flexibility and sufficient radial strength to support the vessel.
US08282677B2 Variable stiffness heating catheter
The variable stiffness heating catheter includes a heating catheter shaft including at least one electrically conductive member, a reinforcing tube with apertures formed around the surface of the reinforcing tube, and at least one coaxial outer layer of a polymer, metal, or both for providing desired variations in stiffness along at least a portion of the length of the shaft. The apertures can be formed as axial or helical slits in the surface of the reinforcing tube, and the reinforcing tube can also be formed to be tapered at the point where the apertures are formed in the reinforcing tube to provide a heating catheter that is torqueable and pushable at the proximal end, yet soft and flexible at the distal end.
US08282671B2 Smart device for non-invasive skeletal adjustment
This invention is an implantable device and system that allows post-operative, non-invasive adjustment of members of the skeletal system. It includes extension-resisting members and a compression-resisting member that connect members of the skeletal system. Post-operative, non-invasive adjustment of the tensions, lengths, widths, and/or torsions of the extension-resisting members changes the relative movement, position, or both movement and position of members of the skeletal system. The compression-resisting member may act as a fulcrum. This invention can help to pioneer the evolution of “smart” orthopedic devices that adjust skeletal biodynamics to address changing clinical needs and changes in patient activity over time. Some promising applications include: dynamic stabilization of the spine; correction of scoliosis; and bone elongation.
US08282668B2 Vein filter
A vessel filter comprising a mounting section having first and second ends and a first and second filtering section. The filter is movable between a collapsed position for delivery to the vessel and an expanded position for placement within the vessel. In the expanded position a first end of the first filtering section converges to form a first converging region and a second end of the second filtering section converges to form a second converging region. The first converging region is positioned radially and axially inwardly of the first end of the mounting section and the second converging region is positioned radially and axially inwardly of the second end of the mounting section.
US08282667B2 Sinus dilation catheter
A balloon dilation catheter includes a substantially rigid inner guide member and a movable shaft coupled to a balloon that is slidably mounted on the substantially rigid inner guide member. To treat a sinus cavity of a subject using the balloon dilation the substantially rigid inner guide member is advanced into a drainage pathway of the sinus (e.g., frontal recess) of the subject via a nasal passageway. The shaft and balloon are advanced in a distal direction over the substantially rigid inner guide member to place the balloon in the drainage pathway. The balloon is inflated to expand or otherwise remodel the drainage pathway.
US08282664B2 Expandable percutaneous sheath
Disclosed is an expandable percutaneous sheath, for introduction into the body while in a first, low cross-sectional area configuration, and subsequent expansion to a second, enlarged cross-sectional configuration. The sheath is maintained in the first, low cross-sectional configuration by a tubular restraint. In one application, the sheath is utilized to provide access for a diagnostic or therapeutic procedure such as percutaneous nephrostomy or urinary bladder access.
US08282660B2 Minimally invasive lung volume reduction devices, methods, and systems
A lung volume reduction system is disclosed comprising an implantable device adapted to be delivered to a lung airway of a patient in a delivery configuration and to change to a deployed configuration to bend the lung airway. The invention also discloses a method of bending a lung airway of a patient comprising inserting a device into the airway in a delivery configuration and bending the device into a deployed configuration, thereby bending the airway.
US08282659B2 Suture manipulating and cutting implement
An implement for manipulating a knotted suture during a surgical procedure, includes an elongated shaft having a proximal end engageable by the user for manipulating the instrument, and a distal end engageable with the knotted suture to be manipulated. The distal end of the elongated shaft has an end face formed with a recess for receiving the knot of the suture. The distal end of the elongated shaft is formed with an open slot starting from a location spaced from the end face and leading to the recess in the end face, such as to enable the knotted suture to be introduced into the slot and the recess by effecting a sidewise movement. The implement further includes a tubular cutter member enclosing the elongated shaft and formed with an annular cutting edge engageable with a suture in the open slot of the shaft upon movement of the elongated shaft with respect to the tubular cutter member, or by vice-versa.
US08282653B2 System and methods for controlling surgical tool elements
A light-weight, compact, highly dexterous surgical robot system for performing in vivo minimally invasive surgeries that allows precise control of position and orientation of surgical tools. The surgical robot system has three rotational degrees of freedom and one translational degree of freedom and is composed of seven links joined by three gear pairs and six turning pairs. The surgical robot system maintains an open space where a surgical tool element enters the patient to avoid self-collisions within the robot system during surgeries.
US08282648B2 Bone cement needle
A needle assembly for dispensing a bone cement mixture is provided. The needle assembly includes a cannula defining an inner lumen, the cannula having an outlet end for dispensing the bone cement mixture from the assembly. The outlet end has at least one tip moveable between an expanded position and a collapsed position. The tip is configured to cut the bone cement mixture in the collapsed position when the cannula is rotated. The needle assembly also has an inner member disposed within the inner lumen of the cannula, which is movable between an extended position and a retracted position. The inner member is operable to hold the tip in the expanded position when the inner member is in the extended position. The tip automatically collapses into the collapsed position when the inner member is in the retracted position. A method of introducing a bone cement mixture into a damaged bone of a patient is also disclosed.
US08282645B2 Metatarsal bone implant cutting guide
A method for guiding a saw blade (22) during preparation of a metatarsal (14) of a foot (10) for a procedure, such as to receive a metatarsal bone implant (20), includes positioning a housing (242) substantially adjacent to the metatarsal (14), coupling an aligner (38) to the housing (242), and aligning a saw guide (30) of the housing (242). The housing (242) includes the saw guide (30) for receiving and guiding the saw blade (22). The foot (10) includes one or more additional metatarsals (142), and the aligner (38) is used to align the saw guide (30) relative to the metatarsal (14) by aligning the aligner (38) to be substantially parallel to and positioned over a longitudinal axis (40) of one of the additional metatarsals (142).
US08282643B2 Arthroscopic method and apparatus for tissue attachment to bone
Methods are described wherein bone constructs of a patient are used to arthroscopically attach sutures to torn or dysfunctional tissue. A suture or multiple sutures are passed through intersecting/bisecting tunnels formed in the bone. An end of the suture extends from each of the tunnels, and the ends are used to secure the tissue to the bone, such as by arthroscopic tying of the ends, and pulling the tissue against the bone. Devices for performing the methods are also described.
US08282642B2 Cervical drill guide apparatus
A drill guide apparatus for aligning a cervical drill bit and a target site in a vertebral body prior to drilling a hole in the vertebral body is disclosed. The apparatus includes a handle assembly, an extension member extending from the handle assembly, a mounting plate disposed on the distal end of the extension member, a guide member proximally extending from the mounting plate and a rotation mechanism operably connecting the handle assembly and the extension member. The rotation mechanism is configured to selectively position the handle assembly relative to the mounting plate. The guide member may include a single or double barrel configuration. The guide member is selectively positionable relative to the mounting plate. The mounting plate may include a protrusion for selectively engaging a second plate.
US08282636B2 Orthopedic external fixator and method of use
An orthopedic apparatus is provided for bridging a first bone unit to a second bone unit. The apparatus is demonstrated on a finger joint, wherein one of the bones and/or ligaments and/or tendons of the joint is/are injured. A method for implanting and using the apparatus also is presented. The apparatus includes a reformably deformable span portion which is generally circular and preferably rhombic. By deforming or reforming the span portion, it can be repositioned laterally, and/or it can be rotated to allow range of rotary motion so as to promote healing.
US08282634B2 Apparatus, system, and method for performing an electrosurgical procedure
A bipolar forceps is provided. The bipolar forceps includes a housing having a shaft including an electrically conductive distal end. A drive assembly is operable to reciprocate an actuation tube within the shaft. A portion of the actuation tube is electrically conductive. An end effector assembly operatively connects to the shaft and includes a pair of first and second jaw members biased in an open configuration. The first and second jaw members are pivotable about a living hinge. Distal reciprocation of the actuation tube causes each of the jaw members towards one another about the living hinge. One of the jaw members is in electrical communication with the distal end of the shaft and the other jaw member is in selective electrical communication with a distal end of the actuation tube such that when the jaw members are in a closed configuration a closed loop electrical circuit is formed.
US08282633B2 High-frequency surgical apparatus and high-frequency surgical method for closure of patent foramen ovale
A high-frequency surgical apparatus for treating patent foramen ovale in a heart includes a flexible probe which has such a length as to allow the probe to be placed in the patent foramen ovale by passing through the blood vessel; an electrode section which, being placed at a distal end of the probe, has three or more electrodes along a longitudinal direction of the probe; a high-frequency power supply section which supplies predetermined high-frequency power to the patent foramen ovale via the electrode section; a switching section which switches among a plurality of signal lines connected to the three or more electrodes; and a high-frequency power control section which controls switching of the switching section so as to supply the high-frequency power to two electrodes.
US08282632B2 Feedpoint optimization for microwave ablation dipole antenna with integrated tip
A microwave ablation system includes a generator operable to output energy and an antenna coupled to the generator via a coaxial cable. The antenna delivers energy to tissue and includes a proximal radiating section and a distal radiating section. The antenna also includes a feedpoint section defined by the portion of the distal radiating section that underlaps the proximal radiating section.
US08282626B2 Portable infusion pump and media player
Some embodiments of a portable infusion pump system can be configured to deliver medicine (e.g., insulin or the like) to a user and to deliver media content to a user. The media content can include, for example, MP3 music and other audio/video data stored in a memory device in the portable system. Thus, in particular embodiments, the portable infusion pump system can serve a dual purpose of providing medication and entertainment for the user from a compact and unobtrusive device.
US08282625B2 Implantable medical device with time for therapeutic output replenishment determination and method therefore
An implantable medical device for producing a variable therapeutic output to a patient. A therapeutic output delivery module requires replenishment following delivery of a predetermined amount of the therapeutic output. A calculator is responsive to a measure of an amount of the therapeutic output actually delivered to the patient for determining a parameter representative of a time at which the therapeutic output delivery module of the implantable medical device should be replenished with the therapeutic substance based at least in part upon the amount obtained from the measure. A method determines a parameter representative of a time at which a therapeutic output module of an implantable medical device should be replenished following delivery of a predetermined amount of therapeutic output. An amount of the therapeutic output actually delivered to the patient is measured. The parameter is calculated based at least in part upon the amount obtained in the measuring step.
US08282624B2 Urinary catheter assembly allowing for non-contaminated insertion of the catheter into a urinary canal
A catheter assembly allowing for non-contaminated insertion of the catheter into the urinary canal. The catheter assembly includes a urinary catheter, a catheter package and a sealing member. The urinary catheter defines a conduit and has a proximal end adapted for insertion into the urinary canal and an opposite distal end. The catheter package has a hose with a cavity for accommodation of the catheter, and a catheter outlet adapted to dismantle the proximal end of the catheter from the catheter package. The sealing member is adapted to provide a substantially liquid-tight seal between the catheter package and the urinary catheter while the catheter is being dismantled.
US08282623B2 Method for treating obesity by extracting food
The present invention is directed to an apparatus and method for treating obesity. A tube is positioned that passes through a patient's abdominal wall into the upper digestive system of the patient. The patient is allowed to carry out his/her everyday affairs including ingesting food. After the patient has ingested food, the food is extracted by pumping it out of the upper digestive system through the tube. The present invention is less invasive than current surgical procedures for reducing weight and allows patients to live a normal and active lifestyle without experiencing adverse side effects.
US08282622B2 Ureteral access sheath
A ureteral access sheath adapted for insertion into a urethra includes an elongate tube extending between a proximal end and a distal end. A handle assembly is disposed at the proximal end and includes enlarged portions which inhibit migration of the sheath into the urethra. The enlarged portions are shaped like the bell of a horn with a concave, distally-facing outer surface and a convex, proximally-facing inner surface. The inner surface functions as a funnel while the outer surface is sized and configured to receive adjacent fingers of a user's hand held in its natural position. In an associated method, this shape of the handle assembly facilitates maintaining the sheath in a stationary position during insertion and removal of instrumentation. The handle assembly can be movable on the tube to facilitate variation of the sheath link in situ.
US08282621B2 Devices and methods for agent-assisted medical procedures
Various embodiments of bulking or cushioning agents or material and related medical devices and methods are disclosed. For example, a method of performing a medical procedure in a tract of a body may include injecting a material in a liquid phase proximate a target site between a first tissue layer and a second tissue layer, allowing the material to transition from the liquid phase to the gel phase in response to a raise in temperature of the material to approximately at or above the predetermined temperature, and performing a surgical procedure on the target site. The material may have the liquid phase at temperatures below a predetermined temperature and a gel phase at temperatures approximately at or above the predetermined temperature.
US08282616B2 Pant-type absorbent article and a method for producing pant-type absorbent articles
A pant-type absorbent article including a chassis structure including a front panel having a front end edge and first and second side edges, a back panel having a back end edge and first and second side edges and a crotch panel arranged between the front and back panels at least one of said front and back panels including an elastic nonwoven/film laminate, and a core being integrated with the chassis structure, the first and second side edges of the front panel being joined by side seams to the corresponding first and second side edges of the back panel. Each side seam is formed at least in part in a weldable connecting member, the connecting member including a first part being secured to a side edge on the front panel and a second part being secured to a corresponding side edge on the back panel, said first and second parts of said connecting member being joined by thermowelding to form said side seam.
US08282615B2 Absorbent article with leak barriers
An absorbent article includes a front region (2), a back region (3) and a crotch region (4) there between. The article further includes substantially longitudinally extending inner (12) and outer (13) leak barriers alongside each side of the absorbent core (9). The inner and outer leak barriers are spaced from each other in the transverse direction (x) of the article. The inner leak barriers (12) extend at least along the part of the crotch region (4) having the narrowest width (w1) in the transverse direction (x), and along a length (b) of at least 5 cm, and the outer leak barriers (13) extend along at least a part of the front region (2) and/or back region (3) of the article, while at least a part of the crotch region (4) along which said inner leak barriers (12) extend is free from raised outer leak barriers (13).
US08282613B2 Disposable urine bag for collecting urine
A disposable urine bag is provided. The bag includes an upper delimiting edge, a lower delimiting edge and lateral delimiting edges defining a space in the bag. The lower delimiting edge includes a drain valve, whose first drain mouthing in a first hollow element communicates with the space in the bag, and whose second mouthing in a second element is situated outside the delimiting edges of the bag. The drain valve is a disposable valve including a seal between the first and the second element and at least one indicator situated in the area of the seal. A disposable urine bag is provided whereby the drain valve seal may be broken without using significant finger strength and without a risk of the user being soiled with urine.
US08282612B1 Methods and devices for intrauterine absorption
The present invention comprises methods and devices for collection of fluids, including cells and cellular materials, from the uterus. A device of the present invention comprises a central tubing member to which, at least, a flexible tubing member and an absorbable member are connected at least at one point. The absorbable member is connected to at least one portion of the central tubing member and to at least one portion of the flexible tubing member. The devices of the present invention are useful in methods of collection of uterine fluids, including blood, cells and cellular material.
US08282610B1 Stabilized implantable vascular access port
The subcutaneously implantable vascular access port has two parts including a body and a wing. The body supports a chamber covered by a septum, with a septum held in place over the chamber by a collar. The chamber is coupleable to a vascular structure, such as through tubing extending from the body, for delivery of medical preparations. The body is preferably elongate in form. The wing is configured to be adjustable in width. In one embodiment the wing rotates relative to the body and has an elongate form similar to that of the body. When the wing is rotated it extends laterally from the body and enhances a stability of the body. In another embodiment, the wing is provided as a deformable wing which can expand laterally out of side openings of a cavern in the body into which the deformable wing is inserted.
US08282601B2 Dispensing fluid from an infusion pump system
Some embodiments of an infusion pump device may include a drive system that accurately and incrementally dispenses fluid from the pump device in a controlled manner. Particular embodiments of the drive system may include a rotational motor that is coupled to a string member, which is used to adjust a pawl relative to a ratchet body. In such circumstances, the drive system can provide a reliable and compact infusion pump device that accurately dispenses the desired volume of fluid.
US08282599B2 Therapeutic catheter with displacement sensing transducer
A catheter device having a proboscis, such as a needle, and a transducer which detects the axial displacement of the proboscis in relation to the distal tip of the catheter. The transducer is positioned at a distal portion of the catheter and may comprise an induction coil or a potentiometer. Axial displacement of the proboscis changes the amount of inductance or resistance in the transducer. This change in inductance or resistance can be calibrated to the amount of axial displacement of the proboscis and provided as feedback to the user.
US08282598B2 External anchoring configurations for modular gastrointestinal prostheses
Components may be used separately or in combination to create anchoring systems for intra-luminal implants for the treatment of metabolic disorders such as obesity and diabetes. Various systems include an external component adapted for deployment around a portion of the gastrointestinal tract (e.g., the duodenum) and an internal component adapted for implantation within the gastrointestinal tract. Various systems use anchors that are based on mechanical interference, elasticity, spring force, shape memory transformation, magnetic attraction, repulsion and/or levitation. Various embodiments rely on longitudinal anchoring of the implants with minimal force against tissue.
US08282596B2 Breastpump with letdown feature
Breastpumps and methods for use in extracting breastmilk, which can be used to generate, among other things, both a letdown or stimulation phase and a milk expression phase, are disclosed.
US08282591B2 Hybrid arteriovenous shunt
An apparatus for positioning a graft and catheter operable for subcutaneous access to the vascular system of a patient. A surgically created, hybrid arteriovenous shunt is provided which comprises a flexible graft and a venous outflow catheter connected to the graft via surgical anastomosis over a cuff. The graft is connected to an arterial source and then to a single lumen venous outflow catheter which deposits dialyzed blood directly into the heart at the right atrium. Methods of surgical placement and performing hemodialysis using embodiments of the apparatus are provided.
US08282589B2 Restraint device and method of use
A restraint device includes first and second restraint and/or support portions adapted to extend around part of a person. First and second connector portions may secure the first and second restraint and/or support portions to the person. A lock member may be used to selectively prevent disconnection of the first and second connector portions. One or more removable tags or other information elements may be carried on at least one of the first and second restraint and/or support portions and may indicate who placed the restraint device on, or removed the restraint device from the person, and/or what time the restraint device was placed or removed. The tags or other elements may include a unique identifier to indicate whether the restraint device had been previously removed from the person after an initial placement. The restraint device may include an electronic information element configured to transmit information related to the wearer.
US08282587B2 Method of and system for joint therapy and stabilization
A joint therapy system and method is shown for proving thermal therapy and joint stability in dual modes of operation. In some embodiments, a treatment system is shown utilizing an orthopedic support for supporting a joint region and having one or more of temperature control capabilities, compression capabilities, and bracing capabilities that may, for example, be used to reduce recover time, limit edema, and protect joints from improper movement while healing from orthopedic surgeries.
US08282585B2 Massager
A massager system includes one or more gear trains coupled to a motor to rotate at least a pair of shafts that each supports a pair of nodules for rotation about the associated shaft. A pillow-shaped outer housing surrounds the motor and number of coupled gear trains with the nodules protruding above the outer housing to facilitate contact with a selected bodily region to knead or otherwise stimulate surface skin in a bodily region.
US08282584B2 Massage chair
A massage chair is adapted to give a massage to a user using a massaging element attached to a massaging unit. The massage chair comprises a body-shape-information acquisition section for acquiring body-shape information of the user based on loads imposed on the massaging element from respective regions of the user, a shoulder-position detection section for detecting a shoulder position of the user based on the body-shape information, and a shoulder-position identification section. The shoulder-position identification section is operable to thrust the massaging element in a direction for a target protrusion distance at the detected shoulder position while measuring a load imposed on the massaging element. Then, the shoulder-position identification section is operable, based on the measured load, to determine whether the detected shoulder position is a true shoulder position. Further, when the detected shoulder position is determined to be mismatched with the true shoulder position, the shoulder-position identification section is operable to vertically move the massaging unit while re-measuring a load imposed on the massaging element, so as to identify the true shoulder position based on the re-measured load.
US08282581B2 Ultrasound treatment clamp
The present invention relates to an ultrasound treatment clamp. The ultrasound treatment clamp comprises ultrasound therapy applicators and handles connected to the ultrasound therapy applicators. The handles are clamp-shaped. The two ultrasound therapy applicators with their central axes overlapping each other are mounted face to face on the two clamps of the clamp-shaped handles respectively. A parallel moving mechanism for keeping the two ultrasound therapy applicators in parallel when moving along with clamps is connected between the two clamps. The present invention has a compact structure, a convenient operation, a low treatment cost, a capability of quickly causing a coagulative necrosis of the diseased part. Furthermore, the present invention has an abroad use in treating many kinds of diseases.
US08282575B2 Endoscopic puncture needle and method of acquiring tissue from a target region by using the endoscopic puncture needle
An endoscopic puncture needle includes a sheath, an outer needle, an outer needle moving member, an inner needle, an inner needle moving member, and an operation portion. The outer needle moves along an axial direction of the sheath in the sheath, and is retractable with respect to a distal end of the sheath. The outer needle moving member is arranged at a proximal end portion of the outer needle, and moves the outer needle with respect to the sheath. The inner needle moves in the outer needle along the axial direction of the sheath, and is retractable with respect to a distal end of the outer needle. The inner needle moving member is arranged at a proximal end portion of the inner needle, and moves the inner needle with respect to the outer needle. The operation portion operates the outer needle moving member and the inner needle moving member.
US08282563B2 Cardiac disease treatment system
ProblemsTo provide a cardiac disease treatment system for accurately diagnosing the functional cause of an abnormality of a cardiac disease by analyzing the hemodynamic state of a patient, automatically performing medication in accordance with the diagnosis result, and treating the cardiac disease.Means for solving problemsThe cardiac disease treatment system is characterized by comprising input means (2) for inputting the cardiac output value of the patient, the left atrial pressure value and/or the right atrial pressure value, first calculating means (31) for calculating the pumping ability value of the left heart or the right heart from the inputted cardiac output and the left or right atrial pressure value, first comparing means (41) for comparing the pumping ability value of the left heart or the right heart with a target pumping ability value, and first medicating means (51) for medicating the patient in accordance with the result of the comparison by the first comparing means (41).
US08282559B2 Method for inducing and monitoring long-term potentiation and long-term depression using transcranial doppler ultrasound device in head-down bed rest
The present invention provides a method for monitoring long-term potentiation and long-term depression, comprising placing a subject in head down bed rest position and monitoring in real-time cerebral mean blood flow velocity using a transcranial Doppler device during psychophysiologic tasks. The method involves using Fourier analysis of mean blood flow velocity data to derive spectral density peaks of cortical and subcortical processes. The effect of head-down bed rest at different time intervals is seen as accentuation of the cortical peaks in long-term potentiation and attenuation of subcortical peaks in long-term depression, relative to baseline. The effect of different interventions could be evaluated for research, diagnosis, rehabilitation and therapeutic use.
US08282554B2 Methods for treatment of sweat glands
A method and system for ultrasound treatment of sweat glands are provided. An exemplary method and system for targeted treatment of sweat glands can be configured in various manners, such as through use of therapy only, therapy and monitoring, imaging and therapy, or therapy, imaging, and monitoring, and/or through use of focused, unfocused, or defocused ultrasound through control of various spatial and temporal parameters. As a result, ablative energy can be deposited at the particular depth at which the aberrant sweat gland population is located below the skin surface.
US08282551B2 Ultrasonic diagnostic apparatus, data analysis method, and data analysis program
An ultrasonic diagnostic apparatus in which a speckle analysis can be made in a simple manner and an analysis result can be promptly displayed. The ultrasonic diagnostic apparatus includes: a transmitting and receiving unit for converting reception signals into digital signals; a signal processing unit for generating envelope data based on the digital signals; an image data generating unit for generating image data based on the envelope data; a speckle analysis unit for generating speckle analysis result data based on the envelope data; a display unit for displaying an ultrasonic image and a corresponding speckle analysis result; and a ROI setting unit for setting a ROI in the ultrasonic image; wherein the speckle analysis unit includes a memory for storing the envelope data, and a computation part for generating the speckle analysis result data based on the envelope data corresponding to the set ROI.
US08282549B2 Signal processing for continuous analyte sensor
A second numerical value 246 is shown, which is representative of a variation of the measured analyte value 242. The second numerical value is preferably determined from a variation analysis based on statistical, clinical, or physiological parameters, such as described in more detail elsewhere herein. In one embodiment, the second numerical value 246 is determined based on clinical risk (for example, weighted for the greatest possible clinical risk to a patient). In another embodiment, the second numerical representation 246 is an estimated analyte value extrapolated to compensate for a time lag, such as described in more detail elsewhere herein. In some alternative embodiments, the receiver displays a range of numerical analyte values that best represents the host's estimated analyte value (for example, +/−10%). In some embodiments, the range is weighted based on clinical risk to the patient. In some embodiments, the range is representative of a confidence in the estimated analyte value and/or a variation of those values. In some embodiments, the range is adjustable.
US08282548B2 Surgical tissue retractor
Novel ergonomically designed hand held surgical tissue Z-shaped retractors. The retractors include retractor plates which are angulated and deviated from the main axis along the handle of the retractor. The retractors may be applicable for general, cosmetic and reconstructive surgeries, cardio, vascular, obstetrics/gynecology applications, and veterinary practices.
US08282545B1 Intra-corporeal surgical retractor
An intra-corporeal surgical retractor for holding tissues and organs in place is provided, including a sealed container, made from a flexible material, having an interior containing a granular substance and a fluid. At least one tube may be provided with one end attached to the container in communication with the interior of the container and the other end connected to a suction mechanism. When the fluid is evacuated from the container, the container constricts around the granular substance and becomes relatively rigid. An absorbent sleeve or layer may be provided surrounding the container. The granular substance may be provided as loose fill or as a layer over at least a portion of the inner wall. Alternatively, the inner walls of the container may be provided with a very rough surface. Further, the outer surface of the bottom of the pouch is enhanced frictionally.
US08282543B2 Surgical instrument and endoscope surgical system having surgical instrument
A surgical instrument having a surgical unit which operates on an operating portion in a body cavity, an accommodation portion capable of accommodating the surgical unit. The surgical instrument having movement manipulation mechanism connected to the surgical unit for moving the surgical unit to a position at which the surgical unit is accommodated in the accommodation portion and to a position at which the surgical unit is exposed from the accommodation portion along the inside of the accommodation portion.
US08282542B2 Flattened tubular mesh sling and related methods
The invention generally relates to surgically implantable supportive slings. More specifically, in various embodiments, the invention is directed to multilayer mesh slings formed from a tubular mesh material.
US08282539B2 Multi-layered bags and methods of manufacturing the same
A bag can include walls formed of a material having multiple layers, which can include two polyolefin layers and a paper layer. The bag can be formed into a sewn-open-mouth configuration in which a stitching element extends through a wall of the bag. The bag can include a grease-resistant seal that substantially prevents grease from escaping from the bag via an opening in the wall through which the stitching element extends.
US08282536B2 Therapeutic body strap
A therapeutic body strap having a first loop and a second loop. Each loop is made of a strip of material. A central strip having a fixture point such that the first and second loops are connected to the central strip at the fixture point. The strap further includes an attachment portion extending from the central strip for attachment to an attachment point on a stationary object. The first and second loops are configured to snugly surround a user's body parts to allow the user to stretch by creating a tension in the attachment portion.
US08282533B1 Resilient stable trampoline board with bindings
A trampoline board includes a resilient body with a foam core. At least one flex zone (e.g., a channel) which acts as a living hinge extends from a first lateral edge to a second lateral edge to facilitate bending to conform to the shape of a depressed trampoline surface. Sandal-like trampoline board bindings are threadedly coupled to inserts molded into the resilient body. Each binding includes a shock absorbing midsole and is devoid of any potentially harmful structures that extend above the ankle of a user, such as the molded support behind the heel characteristic of snowboard bindings. Adjustable cushioned straps secure the sandal-like trampoline board bindings to a user's feet. The insert pack includes a base with a plurality of parallel threaded shanks extending perpendicularly therefrom.
US08282526B2 Method and apparatus to create a pseudo torque phase during oncoming clutch engagement to prevent clutch slip for a hybrid powertrain system
A method for controlling a powertrain comprising an electro-mechanical transmission mechanically-operatively coupled to an engine and an electric machine adapted to selectively transmit mechanical power to an output member through selective application of a plurality of torque-transfer clutches includes monitoring a clutch slip speed, synchronizing an oncoming clutch, and constraining reactive clutch torque limits for the oncoming clutch to achieve a reactive clutch torque that is less than an estimated clutch torque capacity.
US08282524B2 Transmission device for distributing a drive torque to at least two output shafts
A transmission device is proposed for distributing a drive torque to at least two output shafts (Ab1, Ab2), comprising a differential (2) that is permanently connected to the output shafts (Ab1, Ab2), wherein a double planetary gearset (4) is provided co-axially to the output (Ab2) between the differential cage (3) of the differential (2) and the output (Ab2) of one side, said planetary gearset comprising a first sun gear (5) and a second sun gear (6), a first planetary range (7), an intermediate planetary range (8), and an internal gear (9), herein the internal gear (9) is connected to the differential cage (3) and the planet carrier (10) of the planetary gearset (4) is connected to the output (Ab2), wherein the first sun gear (5) meshes with the first planetary range (7) and can be coupled to the housing (G) by means of a brake (11) in order to shift the torque in one direction, and wherein the second sun gear (6) meshes with the intermediate planetary range (8) and can be coupled to the housing (G) by means of an additional brake (19) in order to shift the torque in the opposite direction.
US08282521B2 Wind turbine generator, and method of controlling the wind turbine generator
To enhance durability of a gear transmission mechanism by eliminating play in a gear engagement due to the backlash between the gears (gear clearance) of the gear transmission mechanism in a variable pitch mechanism of blades or a nacelle turning mechanism and further to reduce damages to a gear tooth surface caused by slide of the tooth surface or impact thereon due to slight vibration, the gear transmission mechanism is constructed such that a first pinion gear 20a and a second pinion gear 20b are provided to mesh with a gear wheel 18 respectively and rotated by a first drive motor 32a and a second drive motor 32b respectively, and a controller 36 controls so as to eliminate play in the engagement of the internal gear and the pinion gear due to backlash between the internal gear 18 and the first pinion gear 20a, thereby avoiding generation of a slide and impact force on the gear transmission mechanism even when the external force or the wind acts on the blade 16.
US08282516B2 Ball bat including a tamper-resistant cap
A ball bat includes a transparent or translucent cap attached to a bat barrel. One or more security labels are bonded or otherwise attached to the cap and the barrel such that removal of the cap damages or destroys the one or more security labels, providing an indication that the cap has been removed and that tampering with the interior of the bat may have occurred.
US08282515B2 Hockey blade with wrapped, stitched core
A construct for a hockey blade that includes a foam core. The foam core includes a first core face, a second core face, and a core edge. A first layer of resin preimpregnated tape is wrapped continuously around the first core face, the core edge and the second core face. A thread is stitched along the first layer of preimpregnated tape. A second layer of resin preimpregnated tape wrapped continuously around the first layer of resin preimpregnated tape.
US08282513B2 Racket comprising a joint
The invention relates to a racket for ball games, in particular a tennis or squash racket, comprising a head region for receiving a stringing as well as at least one joint which is provided in the head region and the joint axis of which is arranged essentially perpendicularly with respect to a stringing plane formed by the stringing.
US08282509B1 Collapsible pitching net frame
A foldable device for use in supporting sports nets or the like, the foldable device including: a) a selectively foldable support ring including pivotally secured substantially arcuate sections; and b) a foldable support stand for engaging the ring and having a first open position and a second closed position; and c) at least a part of the ring forming at least one handle when said support stand is in the second position.
US08282505B2 Grooves of golf club heads and methods to manufacture grooves of golf club heads
Embodiments of grooves of golf club heads and methods to manufacture grooves of golf club heads are generally described herein. Other embodiments may be described and claimed.
US08282504B1 Protective cover for a golf club head and method of application
A protective cover for a golf club, such as a driver or wood, is disclosed that remains in place during play to prevent scuffing, scratching, and the like of the surface finish. The golf club includes a head having a striking face portion and a non-planar body portion, and a shaft extending from the head. The protective cover includes a one-piece continuous polymeric film that closely conforms to the shape of at least a portion of the non-planar body portion of the golf club head, such as the entire crown, and a layer of adhesive adhering the polymeric film to the club head. The polymeric film preferably does not cover the face portion of the golf club head so that it has minimal impact on the performance of the golf club. A method of applying the protective cover to the club head is also disclosed.
US08282501B2 Putter-type golf club
A putter-type golf club comprising an alignment system and a club head assembly. The putter-type club head has a body that is preferably composed of aluminum, with a rear weight disk and small inserts composed of a material denser than the material used for the remainder of the club head (excluding the neck of the club). The body has an alignment channel that is approximately the same width as a standard golf ball, and which runs from the face to the rear of the club head. In a preferred embodiment this alignment channel is black or dark in color with a white or light-colored border. The putter-type club has a neck that is inserted laterally through the side of the club head, such that it runs parallel to the face of the club head and for substantially the length of the face.
US08282500B1 Golf performance aid apparatus and related methods for helping a golfer achieve a desirable golf swing
An apparatus and method for training a golfer to achieve the proper club position at impact. The apparatus includes a tether having two ends. One end is connected to the head of a golf club type device at a location offset from the axis of the shaft. The other end is connected to a stationary support. The apparatus is used by causing the user to emulate a golf swing, the resistance in the tether forcing the user to achieve a square club face and forward leaning shaft in the impact zone.
US08282498B2 Play swing systems and methods of play
A play swing system includes a safety harness attached to each seat, as well as other features for interactive and competitive throwing and tossing games. The safety harness may incorporates various games features, and thus encourage use in activities that require at least one free hand, or otherwise increase the risk of slippage and falling from the play swing seat. Various embodiments accommodate as well as challenge the spatial perception, dexterity and reflexes of players of different ages. For examples, younger players might compete by throwing objects at a fixed target mounted on the ground. In other embodiments, the target is moving in synchronization with the oscillatory motion of the adjacent players swing by a physical coupling or attachment. Interactive play is encouraged at the higher skill levels by configuring the targets associated with adjacent seats to face each other. In this embodiment, the players oscillate in opposite directions so that they are closest to the target when the relative velocity is highest. The objects of the associated games can be building a higher score, as well as soaking the other player(s) with water supplied by an external source and actuated by instantaneous or accumulated contact of a throwing object with a target.
US08282494B2 Damper device
A damper device includes damper portions arranged in series with each other in a power transmission path and absorbing torsion by means of elastic force, hysteresis portions arranged in parallel with the damper portions at the power transmission path and absorbing the torsion by means of friction force, an input plate inputting rotational torque into one of the damper portion closest to the input side and the hysteresis portion closest to the input side, an intermediate plate transmitting the rotational torque from the damper portion, arranged at the input side, and the hysteresis portion, arranged at the input side, to the damper portions, arranged at the output side, and the hysteresis portions, arranged at the output side, and an output plate outputting the rotational torque from the damper portion closest to the output side and the hysteresis portion closest to the output side.
US08282493B2 Display, device, method, and computer program for indicating a clear shot
An improved display provides information regarding a projectile trajectory so that a user is informed whether or not there is a clear shot. Such information facilitates accurate, effective, and safe firearm and bow use by providing indications regarding obstacles that are between the shooter and target and which may or may not be in the projectile trajectory. The improved display provides one or more path indicators shown over the cross hairs. In some embodiments the highest point in the projectile trajectory (being a true aim point) is indicated in relation to the visualized target and possible obstacles. An improved rangefinder device generally includes a range sensor operable to determine a first range to a target, a tilt sensor operable to determine an angle to the target relative to the device, and a computing element, coupled with the range sensor and the tilt sensor, operable to determine an accurate projectile trajectory based on the first range and the determined angle. In some embodiments any obstacle in the projectile trajectory is automatically ranged and an indication is provided that the obstacle will interfere with the clear shot. A game display embodiment provides education regarding the technology. Enhanced rangefinders have digital cameras and high-resolution displays. Some embodiments adapt a mobile smart device such as an iPhone with a range sensor to be a high resolution rangefinder with a touch screen, GPS, and video analysis capabilities.
US08282488B2 Method and apparatus for outputting a message at a game machine
The invention allows a casino, or other entity, via a game machine, to provide relevant information at appropriate times, and/or in response to appropriate events, to players using the game machine. A dynamic and flexible system adapted to interact with players on an individual basis by aiding in the management, determination, distribution, and delivery of promotional, inspirational, instructive, informational, communicative, incentive, and other types of messages, is provided. Various methods are provided to ensure that receiving messages at a game machine enhances a player's overall gaming experience by selectively outputting helpful and desirable messages to players while minimizing interference with the players' gaming and to avoid overwhelming players with unsolicited, unwanted, and/or irrelevant messages.
US08282485B1 Constant and shadowless light source
A device is provided for capturing images of targets of interest for interaction with or in response to electronic events, such as may be generated by video games and/or other interactive applications. The device includes a shadowless light source, such as one or more light emitting devices that are capable of emitting light into an environment where the emitted light is in at least a first predetermined frequency range that defines a spectral range outside the range of the fluctuating ambient light. A camera has a light receiving lens and an image sensor for converting the light received through the light receiving lens into image data that is obtained by a processor to form a digital representation of the target of interest. Also, the device may include a filter to substantially block light in an anticipated spectral range of fluctuating ambient light.
US08282484B2 Video game processing apparatus, video game processing method and video game processing program
A game program recognizes a graphic drawn by a player with an input device such as a touch pen (30). An icon corresponding to the graphic is matched and displayed on a display section (20). With such a configuration, the player is able to create a desired icon at a desired position. Thus, the content of the game program may be customized freely and varies widely. Accordingly, the player is able to enjoy a drawing operation with a touch pen. At the same time, it is possible to enhance the flexibility of the development of the game story.
US08282480B2 Candle device for providing transaction verification on a gaming machine
A candle device for a gaming machine including a secondary processor is described. The candle device can include a number of stages that when activated convey information about the status of the gaming machine. The secondary processor, disposed within a secure enclosure in the candle device, can be configured to control peripheral devices disposed with a main cabinet of the gaming machine that receive control commands from a game controller. In particular, the secondary processor can be configured to determine a size and a position of windows on the main touch screen display where a first window is for outputting video content from the game controller and a second window is for outputting video content from the secondary processor. The secondary processor can use the second window to add new features to the gaming machine, such as a verification interface for transactions involving mobile devices.
US08282474B2 Wagering game providing a progressive award having an actual value determined by follow-up game play
A gaming system includes a progressive award having game play and an actual value. The game play has at least one variable element and an expected value that is representative of a value amount that should be won by the player, on average in the long term, via the game play. At least one controller is operative to change a state of the variable element based on received wager inputs at a plurality of gaming terminals such that the expected value of the game play increases as the state of the variable element changes. The state of the variable element is displayed on a display device and, in response to a progressive triggering event, game play is awarded, but not the actual value. The game play is conducted based on the variable element in its current state to determine the actual value, which is awarded to the player.
US08282466B2 Wagering game with high-payout percentage gaming feature
A wagering game system is provided and includes a gaming system for playing a wagering game, including an input device adapted to receive an input from a player of the wagering game, a processor configured to determine a wagering game outcome, and a gambling feature incorporating a game in which a player is statistically more likely to win than to lose, wherein the gambling feature is enabled by a wagering game outcome that includes a winning combination.
US08282459B2 Computer-based, interactive, real-time card selection game
The invention is a method of playing computerized card games against real or virtual players. The cards games are usually variations of poker, where the quality of the players' hands is due to skill and strategy rather than the luck of the draw. Players request desired cards from a computerized dealer without knowledge of which cards other players have requested. A null card, which has no value in determining the outcome of the game, is delivered to players who request the same card as another player has requested regardless of whether the card was requested previously or during the current round. In another embodiment, a null card is delivered only when two or more players request the same card during the current round or if a player requests a card that has already been distributed.
US08282454B2 Video game systems and methods including moving the protected character based with the movement of unprotected game character(s)
Example systems and methods relate to a multi-player video game in which multiple players each supply inputs to a respective input device to control a corresponding game character in a scrolling-type game world displayed on a display screen. A first predetermined input supplied by one of the players to the respective input device protects the one player's game character from harm in the game world and the protected game character moves based on the scrolling/non-scrolling state of the game world in accordance with the movement of one or more unprotected characters. The protecting of the one player's game character is stopped in response to one or more protecting stopping conditions, whereby the game character is again controllable by the one player in response to inputs to the respective input device.
US08282451B2 Plenum partition baffle system
A system for directing airflow within a plenum comprising sizeable, shapeable, and interconnectable baffles that can be nondestructively attached to plenum support structures. The system includes means for removably interconnecting the baffles and also for removably and non-destructively attaching the baffles to plenum support structure without tools.
US08282449B2 Cutting valve and method for making portions
A cutting valve for portioning a paste-like mass, having a partitioning piston which is drivable in a portioning chamber with an inlet relative to the inlet and which comprises a cutting edge which during partitioning is movable to sweep over the inlet, the partitioning piston is drivable in the partitioning process to perform a helical movement with simultaneous translatory and rotatory movement components, so that the cutting edge carries out a draw cut in the mass strand.
US08282448B2 Sharpening device for knife blades
A sharpening device 1 for knife blades comprising a base plate 2 with a guiding slot 6, designed as an incision in the base plate 2, for a knife blade to be sharpened and sharpening rods 10a, 10b disposed on both sides of the guiding slot 6 to be pivotable against an elastically resilient restoring force, wherein the guiding rods 10a, 10b intersect at a point of intersection 11 in the area of the guiding slot 6. At least one of the two walls of the base plate 2, which are disposed opposite to each other and form the guiding slot 6, thereby forms a knife abutment surface 7a, 7b and at least one magnet 20, 21, 22 is mounted to the base plate 2 in the area of the knife abutment surface 7a, 7b.
US08282445B2 Floor finishing apparatus
A floor finishing apparatus includes a chassis, a housing pivotably mounted to the chassis and having a mounting surface and at least partially defining a chamber, and a plurality of floor finishing units mounted to the mounting surface of the housing. The apparatus may include a rolling device carried by the housing and adapted to contact the ground to assist the housing in being pivoted with respect to the chassis.