Document Document Title
US08278461B2 Stable amorphous form of carvedilol dihydrogen phosphate with stabilizer
The present invention provides a novel stable amorphous form of carvedilol dihydrogen phosphate and the process for its preparation that involves reaction of carvedilol base with ortho phosphoric acid in the presence of stabilizer in a suitable solvent or mixture of solvents followed by concentration and isolation. An alternate process for preparation of amorphous form of carvedilol dihydrogen phosphate involves addition of stabiliser to the solution of stable amorphous or crystalline carvedilol dihydrogen phosphate in a suitable solvent or mixture of solvents followed by concentration and isolation. The novel stable amorphous form of carvedilol dihydrogen phosphate is highly stable.
US08278451B2 Pseudoazulenyl nitrones
Disclosed herein are pseudoazulenyl nitrone compounds and methods of using these compounds to trap free radicals and to treat, prevent, or ameliorate various diseases associated with free radicals.
US08278445B2 Preparation methods of azoxystrobin and its analogs
Preparation method of a compound of general formula (I) comprises the following steps: (1) a compound of general formula (II) reacts with a formylating agent in an aprotic solvent at a temperature between −20° C. and 200° C. in the presence of a Lewis acid, then an organic base is added to promote the reaction to obtain an intermediate product; (2) the above intermediate product reacts with a methylating agent in the presence of an alkali at a temperature between −20° C. and 100° C. to obtain the compound of formula (I).
US08278444B2 Organometal complex and light-emitting element using the same
An organometallic complex according to the present invention comprises a structure represented by the following general formula (1). In the formula, R1 to R5 are any one selected from the group consisting of hydrogen, a halogen element, an acyl group, an alkyl group, an alkoxy group, an aryl group, a cyano group, and a heterocyclic group, Ar is an aryl group having an electron-withdrawing group or a heterocyclic group having electron-drawing group, and M is an element of Group 9 or an element of Group 10.
US08278442B2 Bicyclic aryl and heteroaryl compounds for the treatment of metabolic disorders
Compounds of formula (I): or pharmaceutically acceptable salts thereof, are opioid receptor modulators, e.g. mu-opioid receptor antagonists, neutral antagonists or inverse agonists, and are useful for the treatment of metabolic disorders including obesity.
US08278439B2 Synthesis of phosphono-substituted porphyrin compounds for attachment to metal oxide surfaces
A method of making a phosphono-substituted dipyrromethane comprises reacting an aldehyde or acetal having at least one phosphono group substituted thereon with pyrrole to produce a phosphono-substituted dipyrromethane; and wherein the phosphono is selected from the group consisting of dialkyl phosphono, diaryl phosphono, and dialkylaryl phosphono. Additional methods, intermediates and products are also described.
US08278435B2 N-pyrazole A2A receptor agonists
The present disclosure provides a process for the preparation of 2-adenosine N-pyrazole compounds exemplified by the structure shown below that are potent and selective agonists for A2A adenosine receptor, compositions comprising these compounds, and methods for using these compounds to stimulate mammalian coronary vasodilation for imaging the heart.
US08278429B2 Oligonucleotide amplification primers for targeting oncogenic HPV
The present invention relates generally to the field of diagnostic and detection assays. More particularly, the present invention provides methods and reagents including biochips for detecting the presence of, or distinguishing between, one or more analytes in a sample.
US08278428B2 Mitochondrial nucleic acid delivery systems
Nucleic acid mitochondrial delivery systems are provided. These systems are important for delivery of genetic information to a mitochondrion and for treatment of mitochondrial related diseases.
US08278423B2 Monoclonal antibodies and fragment thereof directed against the human Anti-Müllerian Hormone type II receptor (AMHR-II)
The present invention relates to monoclonal antibodies and fragment thereof directed against the human Anti-Müllerian Hormone type II receptor (AMHR-II) and their use for treating and diagnosing cancer diseases, such as ovarian cancers.
US08278421B2 Human antibodies specific for gastrin materials and methods
The present invention relates to materials and methods for human antibodies specific for the peptide hormone gastrin and uses of these antibodies in the treatment of subjects having cancer and other conditions or disorders related to gastrin expression.
US08278419B2 Fibronectin type III domain based scaffold compositions, methods and uses
A protein scaffold based on a consensus sequence of fibronectin type III (FN3) proteins, such as the tenth FN3 repeat from human fibronectin (human Tenascin), including isolated nucleic acids that encode a protein scaffold, vectors, host cells, and methods of making and using thereof have applications in diagnostic and/or therapeutic compositions, methods and devices. In particular, protein scaffold molecules binding to IgG have been identified as useful for diagnostic and/or therapeutic applications.
US08278418B2 Modified animal erythropoietin polypeptides and their uses
Modified animal erythropoietin polypeptides and uses thereof are provide.
US08278415B2 Dimeric high affinity EGFR constructs and uses thereof
Polypeptides comprising EGFR extracellular domains I-III capable of forming dimeric EGF-binding proteins are provided. The dimeric construct of the invention is useful in applications where high affinity EGF binding is desired and can be used to select agents capable of binding to native EGFR in the presence of EGF.
US08278414B2 DNA sequence encoding a retinoic acid regulated protein
The present invention concerns a novel retinoic acid regulated gene whose expression product displays useful morphogenic/mitogenic properties. The present invention further concerns an isolated nucleic acid of SEQ ID NO:1 encoding a retinoic acid regulated expression product having an amino acid sequence of SEQ ID NO:2.
US08278412B2 Polypeptide, nucleic acid molecule encoding it and their uses
A polypeptide containing epitope of the amino acid sequence shown in SEQ ID NO:3 is provided, which is selected from the amino acid sequence of SEQ ID NO:3 and amino acids at 16-32 positions, amino acids at 1-30 positions, amino acids at 50-80 positions and amino acids at 17-200 positions of the amino acid sequence shown in SEQ ID NO:3. The nucleic acid molecule encoding the polypeptide, recombinant vectors and host cells comprising the nucleic acid molecule are also provided. The polypeptide and the nucleic acid molecule encoding it can be used for preparing reagents, kits or devices for diagnosing the diseases characterized by EECP expression and pharmaceutical compositions for preventing or treating the diseases characterized by EECP expression by increasing or inhibiting EECP expression and/or activity.
US08278411B2 Polymer and organic light-emitting device including the same
A polymer and an organic light-emitting device including the same, wherein the polymer has a polymeric unit represented by Formula 1 below:
US08278410B2 Fused thiophenes, articles, and methods thereof
Fused thiophene (FT) compounds, FT polymers, FT containing articles, and methods for making and using the FT compounds and polymers thereof of the formulas, as defined herein.
US08278407B2 RTV-organopolysiloxane compositions and novel organopolysiloxane polycondensation catalysts therefor
RTV-organopolysiloxane compositions are crosslinkable by polycondensation and are devoid of alkyltin-based catalysts; novel organopolysiloxane polycondensation catalysts are useful therefor.
US08278406B2 Bioactive and biocompatible polyurethane-buthanediol-glycosaminoglycan salt copolymers
A bioactive and biocompatible polyurethane-butanediol-glycosaminoglycan copolymer for use in medical implant devices. The biocompatible urethane component being the reaction product of 4,4′-methylene-di-(p-phenyl isocyanate) and poly(tetramethylene oxide)n and further reacted with 1,4-butanediol, wherein n=10 to 40. The bioactive glycosaminoglycan being a salt of hyaluronic acid, such as a cetylpyridinium salt acid having 5 to 10,000 repeating units or a salt of heparin, such as a dimethyldioctadecylammonium salt of heparin has 5 to 65 repeating units or a suitable salt of dermatan sulfate. The weight content of the bioactive glycosaminoglycan is an amount sufficient to render the copolymer bioactive. The copolymers described herein have excellent hemocompatibility and biocompatibility.
US08278404B2 Process for producing copolymer
There are provided (I) a process for producing a copolymer of ethylene, an α-olefin having from 3 to 20 carbon atoms and optionally a polyene, which comprises the step of copolymerizing those monomers in a polymerization reactor by feeding the following components (A), (B), (C1) and (D) to the polymerization reactor: (A) a transition metal complex, (B) an organic aluminum compound, (C1) a halogen-containing compound, and (D) a Lewis base, wherein those components are fed to the polymerization reactor without a preliminary contact of (1) the component (A) with the component (B), (2) the component (A) with the component (C1), (3) the component (B) with the component (C1), and (4) the component (B) with the component (D); and (II) a process for producing said copolymer, which comprises the step of copolymerizing those monomers in a polymerization reactor (i) by feeding to the polymerization reactor the components (A), (B), (D), (C2) a halogen-containing compound, which is a derivative of an aryl group-containing carboxylic acid, and (C3) a halogen-containing compound, which is not a derivative of a carboxylic acid, or (ii) by feeding thereto the components (A), (B), (D), (C3), and (C4) a halogen-containing compound, which is a derivative of a carboxylic acid containing an unsaturated bond-carrying linear organic group.
US08278403B2 Multi-component catalyst systems and polymerization processes for forming broad composition distribution polymers
Propylene polymerization processes, polymers and films formed therefrom are described herein. The propylene polymerization processes generally include contacting propylene and an amount of ethylene with a first metallocene catalyst and a second metallocene catalyst within a polymerization reaction vessel to form a propylene based polymer, wherein the amount is an amount effective to form the propylene based polymer including from about 2 wt. % to about 6 wt. % ethylene, the second metallocene catalyst is capable of incorporating a greater amount of ethylene into the propylene based polymer than the first metallocene catalyst and wherein the first metallocene catalyst is capable of forming a propylene/ethylene random copolymer exhibiting a melting temperature that is greater than that of a propylene/ethylene random copolymer formed from the second metallocene catalyst.
US08278401B2 Radiation or thermally curable barrier sealants
This invention relates to curable sealants that provide low moisture permeability and good adhesive strength after cure. The composition comprises an aromatic compound having meta-substituted reactive groups and a cationic or radical initiator.
US08278397B2 Medical instrument, medical material, and method for production of the medical instrument and medical material
Disclosed are a medical instrument and a medical material each comprising an aliphatic polyester resin composition, which are hardly reduced in strength and impact resistance upon the sterilization by ionizing radiation or have excellent shape-retaining properties after a heat treatment. Specifically, a medical instrument and a medical material both sterilized by ionizing radiation are provided, each of which contains a biodegradable resin and a polycarbodiimide compound in an amount of 0.1 to 10% by weight on the resin. The biodegradable resin is polybutylene succinate, a copolymer of polybutylene succinate, or a mixture of polybutylene succinate and a copolymer of polybutylene succinate with polylactic acid or poly(3-hydroxyalkanoate). A method of producing such medical instrument and medical material is also provided.
US08278396B2 Curing agents for epoxy resins
A curing agent for epoxy resin has one or more five- or six-membered aromatic rings, and substituted on the one or more five- or six-membered rings at least two functionalities reactive with the epoxy selected from the group consisting of hydroxyl, amine, imidazole, azine, hydrazide, anhydride, and Lewis acid groups. Choice of functionality can provide a mixed polymer network, one with a more densely cross-linked polymer structure having a high Tg, and the other with a more linear polymer structure to contribute to stress reduction.
US08278395B2 Process for manufacturing modified conjugated diene polymer, composition comprising the polymer, and tire comprising the composition
The present invention has an object to provide a conjugated diene-based polymer, subjected to a vulcanization treatment to make a vulcanized rubber, the vulcanized rubber useful as a material for tire treads excellent in the balance among wet skid characteristics, low hysteresis loss, abrasion resistance, breaking strength and rigidity, and to provide its manufacturing process. According to the present invention, there is provided the process for manufacturing a modified conjugated diene-based polymer having a modifying group in its molecule, the process including a step of obtaining a conjugated diene-based polymer by polymerizing a conjugated diene compound, or a conjugated diene compound and an aromatic vinyl compound, by using an alkaline metal-based initiator or an alkaline earth metal-based initiator in a hydrocarbon solvent, and a step of reacting active terminals of the polymer with a glycidylamino group-containing low molecular compound having two or more tertiary amino groups and three or more glycidyl groups bonded to the amino groups in a molecule of the compound, and an oligomer of a dimmer or more of the low molecular compound as modifying agents, wherein the reaction is performed using 75 to 95% by mass of the low molecular compound and 25 to 5% by mass of the oligomer based on the total amount of the modifying agents.
US08278393B2 Polyethylene blend component and blends containing the same
According to one aspect, the present invention relates to a low-density polyethylene having a melt index MFR2 of 2.5 to 10.0 g/10 min, a density of 910 to 935 kg/m3, and a dynamic viscosity η0.05 at a shear rate of 0.05 rad/s and a dynamic viscosity η300 at a shear rate of 300 rad/s which satisfy the following relationship: η300≦108 Pa*s+0.0253*η0.05. According to a second aspect, the present invention relates to a low-density polyethylene having a melt index MFR2 of 2.5 to 10.0 g/10 min, a density of 910 to 935 kg/m3, and a phase shift δ0.5 at a frequency of 0.5 rad/s and a phase shift δ300 at a frequency of 300 rad/s, which satisfy the following relationship: tan δ300≧0.45+0.164*tan δ0.5.
US08278391B2 Polypropylene compositions for oriented films
Oriented films and methods of forming the same are discussed herein. The oriented films generally include a propylene based polymer and an additive selected from fluoropolymers, fluoroelastomers and combinations thereof, wherein the additive is present in an amount of from about 50 ppm to about 20,000 ppm.
US08278388B2 Alicyclic epoxy resin composition, cured product thereof, production method thereof, and rubbery polymer-containing resin composition
It is an object of the invention to provide a rubbery polymer-containing resin composition useful as a raw material for a molded article and a cured product having high transparency and excellent mechanical strength: namely, an object of the invention is to provide, for example, a cycloaliphatic epoxy resin composition capable of improving the toughness thereof while maintaining the mechanical strength and transparency of the cycloaliphatic epoxy resin without lowering the heat resistance, a production method thereof and a cured product thereof. A rubbery polymer-containing resin composition of the invention, for example, a cycloaliphatic epoxy resin composition of the invention is a cycloaliphatic epoxy resin composition comprising 100 parts by weight of a cycloaliphatic epoxy resin and 1 to 60 parts by weight of polymer particles with a volume average particle diameter (Mv) of not smaller than 0.01 μm and not larger than 0.5 μm, characterized in that each of the polymer particles comprises at least two layers of an elastic core layer present in the inside thereof and a shell layer present in the outermost side thereof, the elastic core layer consisting of a rubbery polymer with a glass transition temperature of lower than 10° C., and the composition is colorless and transparent.
US08278385B2 Rubber composite and tire using the same
The invention is to provide a rubber composite and tire using the rubber composite, which, when the rubber composite is used as the tread rubber of a tire, enables the tire to have high wear resistance and hence have a long life while presenting a low rolling resistance and enables an automobile that uses the tires to reduce fuel consumption during traveling. The rubber composite of the invention comprises 100 parts by weight of a rubber component composed of at least one kind of rubber, selected from a group of natural rubber, synthetic isoprene rubber and synthetic diene rubber and 10 to 100 parts by weight of a carbon black blended therein, the carbon black is specified to satisfy the relation X/Y≧0.84, where X is the mercury intrusion specific surface area (m2/g), measured by mercury porosimetry and Y is the CTAB specific surface area (m2/g). The tire of the invention is one that uses the above rubber composite as its tread portion.
US08278384B2 Polymer composition
The invention relates to a polymer composition comprising a matrix polymer, silica particles dispersed therein, and a coupling agent and a screening agent for the silica particles, and is characterized in that the screening agent is an alkylamine compound. The polymer composition is particularly suitable for the manufacture of rubber tires with improved rolling resistance.
US08278381B2 Flowable thermoplastics with halogen flame retardancy system
Thermoplastic molding compositions, comprising A) from 10 to 98% by weight of at least one thermoplastic polymer, B) from 0.01 to 50% by weight of B1) at least one highly branched or hyperbranched polycarbonate with an OH number of from 1 to 600 mg KOH/g of polycarbonate (to DIN 53240, part 2), or B2) at least one highly branched or hyperbranched polyester of AxBy type, where x is at least 1.1 and y is at least 2.1, or a mixture of these, C) from 1 to 30% by weight of a flame retardant combination composed of, based on 100% by weight of C), C1) from 20 to 99% by weight of a halogen-containing flame retardant, C2) from 1 to 80% by weight of an antimony oxide, D) from 0 to 60% by weight of other additives, where the total of the percentages by weight of components A) to D) is 100%.
US08278376B2 Flame-retardant poly(arylene ether) composition and its use as a covering for coated wire
A flame retardant poly(arylene ether) composition is described. In addition to the poly(arylene ether), the composition includes a polyolefin component, and a flame retardant composition that includes a metal dialkyl phosphinate. The polyolefin component can be a polyolefin polymer and/or the polyolefin block of a poly(alkenyl aromatic)-polyolefin block copolymer. The composition is particularly suitable as a replacement for poly(vinyl chloride) in insulation for wire and cable.
US08278374B2 Processes for manufacture of a dry strength paper and methods for imparting dry strength to paper using a cationic starch graft polymer
Embodiments of the present disclosure provide for processes for manufacture of a dry strength paper, methods for imparting dry strength to paper using a cationic starch graft polymer, and the like.
US08278371B2 Non-aqueous ink jet ink composition
A nonaqueous inkjet ink composition that at printing by an inkjet printer, is free from clogging of a nozzle of printer head part and that excels in ink delivery stability leading to prints of excellent printing quality. The nonaqueous inkjet ink composition is one containing a pigment, a resin, a pigment dispersant, an organic solvent and an aminated alcohol, characterized in that the content of the aminated alcohol is in the range of 0.01 to 3 mass % based on the whole mass. The nonaqueous inkjet ink composition may be one characterized in that the water extract from the nonaqueous inkjet ink composition exhibits a pH value ranging from 6.0 to 10.0.
US08278369B2 Epoxy-based antiskid adhesive and preparation thereof
An epoxy-based antiskid adhesive having component A and component B, the component A having 1) between 20 and 35 parts of an epoxy resin; 2) between 0.5 and 3 parts of a diluting agent; 3) between 1 and 5 parts of silica; 4) between 20 and 60 parts of quartz sand; 5) between 1 and 6 parts of quartz powder; 6) between 1 and 10 parts of an active calcium; and 7) between 1 and 5 parts of triple superphosphate; and the component B having 1) between 20 and 40 parts of an organic compound-modified amine; 2) between 1 and 5 parts of an accelerator; 3) between 0 and 3 parts of a coupling agent; 4) between 5 and 10 parts of silica; 5) between 20 and 50 parts of quartz sand; 6) between 1 and 10 parts of quartz powder; and 7) between 1 and 10 parts of silica fume.
US08278367B2 Silicon moulding material comprising a two-stage hardening mechanism
A subject-matter of the invention is an impression material with at least one compound with at least two alkenyl groups as component (a), at least one compound with at least one chelating group as component (b), at least one organohydropolysiloxane as component (c), at least one hydrosilylation catalyst as component (d) and at least one compound with a chelatable metal atom as component (e), the chelating group of the component (b) exhibiting no reactive groups which can react with the component (c) and/or the component (d).The invention achieves a long storage stability.
US08278365B2 Carpet waste composite
A composite material is produced from carpet waste and a binding agent, in intimate association, and may also include wood fiber or chips and/or other additives. A method of manufacturing a composite material includes shredding carpet waste, coating the carpet waste with a binding agent, and subjecting the shredded, coated carpet waste to elevated heat and pressure. As an additional step, the composite material may be actively cooled to prevent deformation of the material.
US08278363B2 Fischer-tropsch reactions using heat transfer tubes with a catalyst layer on the outside surfaces
A method of converting synthesis gas into Fischer-Tropsch products comprises: (a) charging synthesis gas to a reactor comprising a shell, having an inlet nozzle near one end for receiving synthesis gas and an outlet nozzle near the opposite end for discharging products, with a plurality of heat transfer tubes inside the shell, having associated therewith means to pass heat transfer fluids through the inside of said heat transfer tubes to remove heat, and whereby the outside surfaces of said tubes have a layer of Fischer-Tropsch catalyst, (b) converting exothermically on said catalyst layer at least a portion of said synthesis gas to produce heat and Fischer-Tropsch products, (c) removing heat from said catalyst layer by passage of a heat transfer fluid through the inside of said tubes, and (d) recovering Fischer-Tropsch products from said reactor.
US08278360B2 Behavior-disrupting agent and behavior-disrupting method of argentine ant
Provided are a behavior-disrupting agent of Argentine ants for controlling them or suppressing their reproduction is a safer and more effective manner, and the behavior-disrupting method of them. More specifically, a behavior-disrupting agent of Argentine ants comprising Z-9-hexadecenal, and a behavior-disrupting method of Argentine ants comprising a step of using the behavior-disrupting agent are provided based on the finding that the behavior of Argentine ants is disrupted by emission of Z-9-hexadecenal, which is a trail pheromone, into the atmosphere.
US08278356B2 Phloroglucinol derivatives having selectin ligand activity
Pharmaceutical compositions comprising at least one compound of the formula (I) and a pharmaceutically acceptable carrier which is useful in a medicine wherein the symbols and substituents have the following meaning —X— is e.g. and Y being e.g. or the pharmaceutically acceptable salts, esters or amides and prodrugs can be applied to modulate the in-vitro and in-vivo binding processes mediated by E-, P- or selectin binding.
US08278354B2 Method for increasing ruminant fertility
Methods for reducing the likelihood of embryonic death in a female ruminant by feeding the ruminant for at least 30 days after conception an effective amount of free-flowing fatty acid calcium salt product comprising from about 1 to 10% by weight of eicosapentaenoic acid (EPA) and from about 1 to about 10% by weight of decosahexaenoic acid (DHA).
US08278353B2 Enhanced bimatoprost ophthalmic solution
A composition comprising from 0.005% to 0.02% bimatoprost by weight and from 100 ppm to 250 ppm benzalkonium chloride, wherein said composition is an aqueous liquid which is formulated for ophthalmic administration is disclosed herein.
US08278351B2 Natural marine source phospholipids comprising polyunsaturated fatty acids and their applications
A phospholipid extract from a marine or aquatic biomass possesses therapeutic properties. The phospholipid extract comprises a variety of phospholipids, fatty acid, metals and a novel flavonoid.
US08278349B2 Cancer treatment using FTS and 2-deoxyglucose
Methods of treating cancer by administering effective amounts of a Ras antagonist comprising FTS, or analogs thereof, or a pharmaceutically acceptable salt, and 2-deoxyglucose (2DG) to a patient are disclosed. Pharmaceutical compositions useful in treating cancer containing a Ras antagonist comprising FTS, or analogs thereof, or a pharmaceutically acceptable salt, and 2DG are also disclosed.
US08278348B2 Chondropsin-class antitumor V-atpase inhibitor compounds, compositions and methods of use thereof
A composition comprising a substantially purified compound of the formula: in combination with at least one additional therapeutic agent, and methods of preventing or treating cancer and a condition treatable by the inhibition of vacuolar-type (H+)-ATPase.
US08278346B2 Di-tin fused thiophene compounds and polymers and methods of making
Di-tin fused thiophene (FT) compounds, FT polymers, such as of the formula -{-(FTx)-(Ar)m-}n-, FT polymer containing articles or devices, and methods for making and using the FT compounds and polymers thereof of the formulas, as defined herein.
US08278345B2 Inhibitors of glutaminyl cyclase
The present invention relates to compounds of formula (I), combinations and uses thereof for disease therapy, R1 represents heteroaryl, -carbocyclyl-heteroaryl, -alkenylheteroaryl or -alkylheteroaryl; R2 represents hydrogen; halogen; alkenyl; alkynyl; -alkenylaryl; -alkenylheteroaryl; alkyl, which may optionally be substituted by one or more groups selected from halogen, hydroxyl, alkoxy-, -thioalkyl, —C(O)OH and —C(O)O-alkyl; carbocyclyl, which may optionally be substituted by one or more groups selected from alkyl, halogen, hydroxyl, alkoxy-, -thioalkyl, —C(O)OH and —C(O)O-alkyl; -alkylcarbocyclyl; -alkylheterocyclyl; aryl; heteroaryl; heterocyclyl; -alkylaryl; -alkyl(aryl)2, -alkylheteroaryl; -aryl-heteroaryl; -heterocyclyl-aryl; -aryl-aryl; -heteroaryl-aryl; -heteroaryl-heteroaryl, and —C(O)R4; R3 represents halogen; alkyl optionally substituted by one or more groups selected from halogen, hydroxyl, alkoxy, thioalkyl, —C(O)OH and —C(O)O-alkyl; aryl; heteroaryl; —C(O)R5; R4 and R5 independently represent alkyl, aryl, heteroaryl, -alkylaryl, -alkylheteroaryl, carbocyclyl, heterocyclyl, -alkylcarbocyclyl and -alkylheterocyclyl, with the proviso that, when R1 is imidazolyl, -carbocyclyl-imidazolyl, -alkenyl-imidazolyl or -alkyl-imidazolyl, then R3 may not be —C(O)R5.
US08278340B2 Inhibition of biofilms in plants with imidazole derivatives
Disclosure is provided for methods of preventing, removing or inhibiting microbial biofilm formation or microbial infection in a plant or plant part thereof, including applying thereto a treatment effective amount of an active compound as described herein, or an agriculturally acceptable salt thereof. Methods of enhancing a microbicide (e.g., including a copper, antibiotic, bacteriophage, etc.) and/or plant defense activator are also provided, including applying an active compound as described herein. Compositions comprising an active compound as described herein in an agriculturally acceptable carrier are also provided, and in some embodiments the compositions further include a microbicide (e.g., including copper, antibiotic, bacteriophage, etc.) and/or plant defense activator.
US08278339B2 Valsartan salts
The invention relates to new salts of valsartan or crystalline, also partly crystalline and amorphous salts of valsartan, the respective production and usage, and pharmaceutical preparations containing such a salt.
US08278332B2 Photostabilization of retinoids with alkoxycrylene compounds
The photostabilizing electronic excited state energy—particularly singlet state energy from retinoid compounds—has been found to be readily transferred to (accepted by) α-cyanodiphenylacrylate compounds having an alkoxy radical in the four (para) position (hereinafter “alkoxycrylenes”) on one of the phenyl rings having the formula (I): wherein one of R1 and R2 is a straight or branched chain C1-C30 alkoxy radical, preferably C1-C8, more preferably methoxy, and the non-alkoxy radical R1 or R2 is hydrogen; and R3 is a straight or branched chain C1-C30 alkyl radical, preferably C2-C20. The alkoxycrylene compounds of formula (I) significantly increase the photostability of retinoid compounds in a composition by at least 3-fold.
US08278328B2 Compounds which have activity at M1 receptor and their uses in medicine
Compounds of formula (I) or a salt thereof are provided: wherein R4, R5, R6, Q, A, Y and R are as defined in the description. Uses of the compounds as medicaments and in the manufacture of medicaments for treating psychotic disorders, cognitive impairments and Alzheimer's Disease are disclosed. The invention further discloses pharmaceutical compositions comprising the compounds.
US08278323B2 Opioid antagonists
Certain quinolizidine and octahydropyridopyrazine compounds, pharmaceutical compositions, and methods of their use, inter alia, as opioid receptor antagonists are disclosed.
US08278322B2 HCV NS3 protease inhibitors
The present invention relates to macrocyclic compounds of formula (I) that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease, their synthesis, and their use for treating or preventing HCV infections.
US08278321B2 Small molecule inhibition of intracellular transport
The present disclosure characterizes the activity of Golgicide A (GCA), as a potent, specific and reversible small molecule inhibitor of Golgi BFA resistance factor 1 (GBF1) function. A mutant GBF1 gene that is resistant to GCA is also described. Methods of using GCA and the GCA-resistant GBF1 gene are described including methods for modulating GBF1 activity for research and therapeutic purposes. Also described are compositions incorporating a GCA-resistant GBF1.
US08278320B2 Azabicyclo[2.2.1]heptane compounds as alpha-7 nicotinic acetylcholine receptor ligands
The disclosure provides compounds of formula I, including Ia, Ib, Ic, or Id, including their salts, as well as compositions and methods of using the compounds. The compounds are ligands for the nicotinic α7 receptor and may be useful for the treatment of various disorders of the central nervous system, especially affective and neurodegenerative disorders.
US08278319B2 Substituted spiroamine compounds
Substituted spiroamine compounds corresponding to the formula (I) In which m, n, o, p, Q, r, s, t, R1, R2, R3, R4a, R4b, R5a, R5b, R6a, R6b, R7, R8, R9, R10 and R11 have defined meanings; a process for the preparation of such compounds, pharmaceutical compositions containing such compounds and the use of substituted spiroamines for the treatment or inhibition of pain and/or other conditions mediated by the bradykinin 1 receptor.
US08278311B2 Substituted pyrimidine derivatives
The present application describes substituted pyrimidine compounds of formula (I) wherein X, A1, R1, R2, R3, R4, R5, R6, R7, R8, R9, p, q, r, v, and w are defined in the specification, compositions comprising such compounds, methods for making the compounds, and methods of treating and preventing the progression of diseases, conditions and disorders using such compounds and compositions.
US08278310B2 Amine salts of a CRTH2 antagonist
Provided are amine salts of {4,6-bis(dimethylamino)-2-(4-(4-(trifluoromethyl)benzamido)benzyl)pyrimidin-5-yl}-acetic acid, processes for their preparation, pharmaceutical compositions containing them, and their use for treating, preventing, or ameliorating one or more symptoms of a CRTH2-mediated disorder or disease.
US08278305B2 Myosin light chain kinase inhibitor compounds, compositions and related methods of use
Pyridazinyl compounds, compositions and related methods of use.
US08278304B2 Substituted 4-hydroxypyrimidine-5-carboxamides
The present invention relates to substituted 4-hydroxypyrimidine-5-carboxamides useful as HIF prolyl hydroxylase inhibitors to treat anemia and like conditions.
US08278302B2 Substituted piperidines as CCR3 antagonists
Object of the present invention are novel substituted compounds of the formula 1, wherein A, R1, R2, R3 and R4 are defined as in the description. Another object of the present invention is to provide antagonists of CCR3, more particularly to provide pharmaceutical compositions comprising a pharmaceutically acceptable carrier and a therapeutically effective amount of at least one of the compounds of the present invention or a pharmaceutically acceptable salt thereof.
US08278301B2 2-alkylbenzoxazole carboxamides as 5HT3 modulators
Compounds of formulae I and II: are disclosed as 5-HT3 inhibitors. Those compounds are useful in treating CINV, IBS-D and other diseases and conditions.
US08278299B2 Pyrimidinediamine kinase inhibitors
The present invention provides pyrimidinediamine compounds useful for inhibiting kinase activity, including the activity of polo-like kinase 1 (PLK1). Also provided are pharmaceutical compositions comprising these compounds and methods of treating diseases associated with kinase activity, in particular enhanced PLK1 catalytic activity, such as diseases associated with abnormal cell proliferation, including neoplastic disorders.
US08278297B2 Protein kinase inhibitors
In one aspect, the invention provides compounds of Formula I or pharmaceutically acceptable salts thereof. In another aspect, the invention provides methods for treatment of diseases or disorders mediated by a protein kinase, comprising administering a therapeutically effective amount of a compound of this invention.
US08278296B2 Manipulation of brain CDP-diacylglycerol and uses thereof
Provided herein methods of screening for potential antidepressant compounds effective to increase production of cellular CDP-diacylglycerol and synthesis of inositol phospholipid in depression-related areas of the brain. Also, provided are methods of diagnosing and treating depressive or mood disorders in a subject by administering these screened antidepressant compounds. Further provided is a method of determining the therapeutic efficacy of an antidepressant drug regimen by comparing the ratio of CDP-diacylglycerol/inositol phosphate after treatment to a basal ratio in a subject.
US08278294B2 Substituted isoquinoline and isoquinolinone derivatives as inhibitors of Rho-kinase
The invention relates to 6-substituted isoquinoline and isochinolone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.
US08278288B2 Organosiloxanes containing ester derivatives of ascorbic acid
Organosiloxanes containing ester derivatives of ascorbic acid are disclosed having the formula (RiSiO)11Ro-Ii)Si—X-A wherein R is an alkyl group containing 1 to 6 carbon atoms, n is 1 to 3 inclusive, X is a divalent organic linking group, A is an ester derivative of ascorbic acid. A method of making an organosiloxane containing ester derivatives of ascorbic acid and the products prepared according to the method arc also taught. The compounds and compositions of the present disclosure are useful to affect tissue lightening when applied topically to keratinaceous tissue.
US08278286B2 Use of gp130 activators in diabetic neuropathy
The invention relates to the use a substance signaling through gp130 for the manufacture of a medicament for the treatment and/or prevention of diabetic neuropathy. The use of IL-6 is preferred.
US08278284B2 Therapeutic agents for diseases associated with apoptotic degeneration in ocular tissue cells that use SIV-PEDF vectors
The present invention provides novel methods for treating diseases associated with apoptotic degeneration in ocular tissue cells by effective administration of pigment epithelium derived factor (PEDF). The present inventors studied PEDF as a means to prevent ganglion cell death, the final pathology of glaucoma. The present invention is particularly focused on SIV vectors for effective methods for delivering PEDF, and constructed an SIV-PEDF vector. When the SIV-PEDF vector was administered subretinally to an ischemia reperfusion model and NMDA-induced model, a significant suppression effect on ganglion cell death was observed. The present inventors therefore discovered that the SIV-PEDF vector is an effective pharmaceutical agent for treating diseases associated with apoptotic degeneration in ocular tissue cells, such as glaucoma.
US08278283B2 6-disubstituted or unsaturated bicyclic nucleic acid analogs
The present disclosure describes 6-disubstituted bicyclic nucleosides, oligomeric compounds prepared therefrom and methods of using the oligomeric compounds. More particularly, the 6-disubstituted bicyclic nucleosides each comprise a 2′-O—C(Ri)(R2)-4′ or 2′-O—C=(R3)(R.4)-4′ bridge wherein each R is, independently a substituent group and Ri and R2 include H. The 6-disubstituted bicyclic nucleosides are useful for enhancing properties of oligomeric compounds including nuclease resistance. In certain embodiments, the oligomeric compounds provided herein hybridize to a portion of a target RNA resulting in loss of normal function of the target RNA.
US08278281B2 Triazole compounds and methods of making and using the same
The present invention provides triazole macrocyclic compounds useful as therapeutic agents. More particularly, these compounds are useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. The compounds have the following structure: wherein T is the macrocyclic part.
US08278280B2 Antagonists of the bradykinin B1 receptor
The present invention relates to composition of matter involving bradykinin B1 receptor antagonist peptides conjugated to a multivalent vehicle, including peptides conjugated to multivalent PEG. These compositions can be used as therapeutics or prophylactics against diseases or conditions, such as inflammation or pain, linked to the bradykinin B1 receptor.
US08278277B2 Delivery of hydrophilic drugs
Compositions comprising a lipophilic derivative of a hydrophilic drug and an amphiphile compound for use in therapy of the human or animal body are provided. Methods of medical treatment, wherein a composition according to the invention is administered to a human or animal body also form part of the invention. It is preferred that the drug is delivered to the brain.
US08278272B2 GLP-1, exendin-4, peptide analogs and uses thereof
The invention relates to novel polypeptide analogues of GLP-1 and exendin-4. The polypeptide, in a preferred embodiment, is insulinotropic and long-acting. Preferably, the polypeptide's insulinotropic effect is comparable to or exceeds the effect of an equimolar amount of GLP-1 or exendin-4. The invention also relates to a method of treating a subject with diabetes, comprising administering to the subject the polypeptide of the invention in an amount that has an insulinotropic effect. The invention also relates to methods of using GLP-1, exendin-4, and polypeptide analogues thereof for neuroprotective and neurotrophic effects.
US08278271B2 Inhibiting collagen-induced platelet aggregation and activation with peptide variants
The present invention provides peptides consisting of L- and/or D-amino acids and combinations thereof, which affect platelets by action on the collagen receptor, glycoprotein VI (GPVI). More specifically, however, the peptides act on the GPVI-FcRγ signaling complex. The invention also provides lipid and sugar conjugated peptides comprising L- or D-amino acids. The invention still further provides a method of designing of the peptides and lipid- and/or sugar-conjugated peptides comprising L- or D-amino acids. The present invention further relates to the therapy of various disease states involving the use of these peptides and compounds. Specifically, the peptides and compounds are useful in the treatment and/or prevention of a disease or condition involving platelet activation and aggregation, and more particularly, collagen-induced platelet activation and aggregation. They also are useful in the production of medical devices comprising peptide matrices (i.e., for example, cardiovascular stents).
US08278264B2 Compositions and methods for enhancing drug delivery across and into ocular tissues
This invention provides compositions and methods for enhancing delivery of drugs and other agents across epithelial tissues, including into and across ocular tissues and the like. The compositions and methods are also useful for delivery across endothelial tissues, including the blood brain barrier. The compositions and methods employ a delivery enhancing transporter that has sufficient guanidino or amidino sidechain moieties to enhance delivery of a compound conjugated to the reagent across one or more layers of the tissue, compared to the non-conjugated compound. The delivery-enhancing polymers include, for example, poly-arginine molecules that are preferably between about 6 and 25 residues in length (for example, SEQ ID NO:86).
US08278263B2 Method of regulating mammalian target-of-rapamycin activity by interaction between phospholipase D and raptor
The present invention relates to a method of regulating mammalian target-of-rapamycin (mTOR) by regulating a phospholipase D (PLD) activity that generates a complex with mTOR. Further, the present invention also relates to a method of screening inhibitors of mTOR, and a method and a composition for treating mTOR-related metabolic diseases by inhibiting mTOR.
US08278259B2 Liquid membrane-compatible detergent composition
The invention relates to a liquid detergent concentrate composition comprising an emulsion having a water phase and an oil phase, the composition comprising 5-30 wt-% of one or more alkalinity source 1-70 wt-% of at least one nonionic surfactant 0.01-10 wt-% of at least one crosslinked or partly crosslinked polyacrylic acid or polymethacrylic acid. Furthermore the invention relates to a stable aqueous use solution, comprising a liquid detergent concentrate according to the invention and to a method for washing textiles with the aqueous use solution.
US08278255B2 Unexpected shear stability benefits of synthetic oils and viscosity modifier combinations
In one embodiment, a lubricating oil with favorable shear stability is disclosed. The lubricating oil comprising a major amount of base stock selected from the group consisting of Group II, Group III, Group IV, Group V, and any combination thereof, a viscosity index improver comprising a polymethacrylate with a permanent shear stability index of less than 45 defined by ASTM 5621 with 10 percent polymer in a Group I mineral oil, an antioxidant additive and a corrosion additive. In a second embodiment a method of improving shear stability is disclosed. In a third embodiment, a method of blending an oil to provide improved shear stability and favorable viscosity index is disclosed.
US08278249B2 Composition for forming thick oxide superconductor film and process for producing thick tape-shaped oxide superconductor film
Disclosed is a composition for forming a thick oxide superconductor film, the oxide being an RE-BA—Cu based oxide, wherein RE is at least one element selected from the group consisting of Y, Nd, Sm, Gd, Eu, Yb, Pr, and Ho. The composition contains an RE salt of a keto acid having 4 to 8 carbon atoms as an RE component, barium trifluoroacetate as a Ba component, at least one copper salt selected from the group consisting of a copper salt of a branched saturated aliphatic carboxylic acid having 6 to 16 carbon atoms and a copper salt of an alicyclic carboxylic acid having 6 to 16 carbon atoms as a Cu component, and an organic solvent dissolving these metal salt components. In the composition, the RE to Ba to Cu molar ratio is 1:1.3 to 2.2:2.4 to 3.6 and the content of the organic solvent is 25% to 80% by weight.
US08278245B2 Corrosion inhibitors for aqueous pesticide formulations
The present invention relates to aqueous-containing pesticide concentrates containing an ionic nitrate salt additive as a corrosion inhibitor as well as pesticide compositions prepared from these concentrates and to the use of said compositions for controlling pests.
US08278241B2 Amorphous silica-alumina composition and a method of making and using such composition
Described is a novel amorphous silica-alumina composition having a high ratio of pore volume contained in large pores to pore volume contained in medium to small pores. The amorphous silica-alumina composition also may have the characteristic of a strong aluminum-NMR penta-coordinated peak representing greater than 30% of the total aluminum and a method of making such novel amorphous silica-alumina composition using a pH swing preparation method.
US08278238B2 Triplet emitter having condensed five-membered rings
The present invention relates to light emitting compounds, especially to triplett emitters suitable for electrooptical applications. Compounds according to the invention are organometallic complexes of a metal, preferably Ir, having a backbone of one five-membered ring that is linked to a five- or six-membered ring, by an intermediate six-membered ring. These compounds are suitable for adaptation to the emission of light in the UV to NIR range by adaptation of atoms or groups within at least one of the five-membered or six-membered ring structures.
US08278236B2 Method for catalytically coating ceramic honeycomb bodies
The invention relates to a process for coating ceramic honeycomb bodies with a coating suspension containing, in a carrier liquid, catalyst components as solids and/or in dissolved form. The honeycomb bodies have parallel flow channels running through them. The walls of the flow channels generally have an open pore structure. To coat the channel walls and in particular also the interior surfaces of the pores with the coating suspension, it is proposed that the flow channels be temporarily alternately closed and the coating suspension be forced through the open pore structure of the channel walls. The coating is subsequently dried and calcined. To close the flow channels, it is possible to use thermally or chemically decomposable or soluble compositions which are decomposed or dissolved either during calcination or by means of a subsequent chemical treatment. The coated honeycomb bodies are preferably used for the purification of exhaust gases from automobiles.
US08278234B2 Process for the regeneration of catalysts for the treatment of hydrocarbons
A subject-matter of the present invention is a process for the regeneration of a catalyst comprising at least one metal from Group VIII and at least one metal from Group VIB which are deposited on a refractory oxide support, comprising: at least one first step of heat treatment of the catalyst in the presence of oxygen and at a temperature ranging from 350° C. to 550° C.; at least one second step of deposition, at the surface of the catalyst, of one or more additive(s) of formula (I):
US08278233B2 Translucent polycrystalline sintered body, method for producing the same, and arc tube for high-intensity discharge lamp
A translucent polycrystalline sintered body is mainly composed of an alumina, is suitable for the manufacture of an arc tube for a high-intensity discharge lamp, and has an average grain diameter of 35 to 70 μm, preferably 50 to 60 μm. In a case where the sintered body is in a 0.5-mm-thick flat plate shape, the in-line transmittance of the sintered body is 30% or more, preferably 50% or more. In this case, the ratio between maximum and minimum in-line transmittance values is 2:1 to 1:1 in the visible region of 360 to 830 nm. The bending strength of the sintered body is 250 MPa or more, preferably 300 MPa or more.
US08278230B2 Perfume systems
The present application relates to perfume systems and consumer products comprising new perfumes and/or such perfume systems, as well as processes for making and using such perfume systems and consumer products.
US08278228B2 Sound absorbing materials as vehicle exterior equipment and manufacturing method thereof
A sound absorbing material 10 as vehicle exterior equipment according to the present invention includes a non-woven fabric 20 including a main fiber and a binder fiber. In the sound absorbing material 10 as vehicle exterior equipment, powdery resin is applied to the surface 20a of the non-woven cloth 20. The powdery resin and the non-woven fabric 20 are heated, compressed and cooled to form a resin layer 30. The resin layer 30 is porous due to particle residue parts 30b where parts of the powdery resin remain in particulate form. The non-woven fabric 20 of the sound absorbing material 10 as vehicle exterior equipment can be constituted from two types of non-woven fabrics 22, 24 superimposed together.
US08278224B1 Flowable oxide deposition using rapid delivery of process gases
Methods and apparatus for filling gaps on partially manufactured semiconductor substrates with dielectric material are provided. In certain embodiments, the methods include introducing a first process gas into the processing chamber and accumulating a second process gas in an accumulator maintained at a pressure level substantially highest than that of the processing chamber pressure level. The second process gas is then rapidly introduced from the accumulator into the processing chamber. An excess amount of the second process gas may be provided in the processing chamber during the introduction of the second process gas. Flowable silicon-containing films forms on a surface of the substrate to at least partially fill the gaps.
US08278221B2 Method of forming a hard mask and method of forming a fine pattern of semiconductor device using the same
A method of forming hard mask employs a double patterning technique. A first hard mask layer is formed on a substrate, and a first sacrificial pattern is formed on the first hard mask layer by photolithography. Features of the first sacrificial pattern are spaced from one another by a first pitch. A second hard mask layer is then formed conformally on the first sacrificial pattern and the first hard mask layer so as to delimit recesses between adjacent features of the first sacrificial pattern. Upper portions of the second hard mask layer are removed to expose the first sacrificial pattern, and the exposed first sacrificial pattern and the second sacrificial pattern are removed. The second hard mask layer and the first hard mask layer are then etched to form a hard mask composed of residual portions of the first hard mask layer and the second hard mask layer. A fine pattern of a semiconductor device, such as a trench isolation region or a pattern of contact holes, can be formed using the hard mask as an etch mask.
US08278220B2 Method to direct pattern metals on a substrate
A microscopic metallic structure is produced by creating or exposing a patterned region of increased conductivity and then forming a conductor on the region using electrodeposition. In some embodiments, a microscopic metallic structure is formed on a substrate, and then the substrate is etched to remove the structure from the substrate. In some embodiments, a focused beam of gallium ion without a deposition precursor gas scans a pattern on a silicon substrate, to produce a conductive pattern on which a copper structure is then formed by electrochemical deposition of one or more metals. The structure can be freed from the substrate by etching, or can used in place. A beam can be used to access an active layer of a transistor, and then a conductor can be electrodeposited to provide a lead for sensing or modifying the transistor operation while it is functioning.
US08278219B2 Method for purifying chemical added with chelating agent
A chelate complex is removed from a chemical which is used in a semiconductor production process and contains a compound having a chelating ability, and the cleaning load is also reduced. Specifically disclosed is a method for purifying a chemical which is used in a semiconductor production process and contains a compound having a chelating ability, wherein a chelate complex which is formed from impurity metals such as nickel and copper contained in an alkaline chemical is removed from the chemical by treating the alkaline chemical with an organic complex adsorbing material.
US08278218B2 Electrical conductor line having a multilayer diffusion barrier for use in a semiconductor device and method for forming the same
An electrical conductor having a multilayer diffusion barrier of use in a resultant semiconductor device is presented. The electrical conductor line includes an insulation layer, a diffusion barrier, and a metal line. The insulation layer is formed on a semiconductor substrate and having a metal line forming region. The diffusion barrier is formed on a surface of the metal line forming region of the insulation layer and has a multi-layered structure made of TaN layer, an MoxOy layer and an Mo layer. The metal line is formed on the diffusion barrier to fill the metal line forming region of the insulation layer.
US08278212B2 Method for manufacturing semiconductor memory element and sputtering apparatus
The present invention provides a method for manufacturing a semiconductor memory element including a chalcogenide material layer and an electrode layer, each having an improved adhesion, and a sputtering apparatus thereof. One embodiment of the present invention is the method for manufacturing a semiconductor memory element including: a first step of forming the chalcogenide material layer (113); and a second step of forming a second electrode layer (114b) on the chalcogenide material layer (113) by sputtering through the use of a mixed gas of a reactive gas and an inert gas, while applying a cathode voltage to a target. In the second step, introduction of the reactive gas is carried out at a flow rate ratio included in a hysteresis area (40) appearing in the relationship between a cathode voltage applied to the cathode and the flow rate ratio of the reactive gas in the mixed gas.
US08278210B2 Manufacturing method of semiconductor device
In a modern 0.15 μm power MOSFET, aluminum voids (voids formed in an aluminum-type electrode) are generated frequently in trench portions (source contact trenches) caused by the reduction of a cell pitch for refinement. It is considered to be attributable to the defects which are generated mainly due to a sudden increase of the aspect ratio from 0.84 in the previous generation to 2.8 in the current generation. Accordingly, concave portions of repetitive trenches having a high aspect ratio are filled with an aluminum-type metal by ionized sputtering throughout the processing, from the formation to the filling of an aluminum-type metal seed film.
US08278204B2 Methods for forming wiring and manufacturing thin film transistor and droplet discharging method
It is required that a line width of a wiring is prevented from being wider to be miniaturized when the wiring or the like is formed by a dropping method typified by an ink-jetting method. The invention provides a method for narrowing (miniaturizing) a line width according to a method different from a conventional method. One feature of the invention is that a plasma treatment is performed before forming a wiring or the like by a dropping method typified by an ink-jetting method. As the result of the plasma treatment, a surface for forming a conductive film is modified to be liquid-repellent. Consequently, a wiring or the like formed by a dropping method can be miniaturized.
US08278191B2 Methods and systems for metal-assisted chemical etching of substrates
Disclosed herein are various embodiments related to metal-assisted chemical etching of substrates on the micron, sub-micron and nano scales. In one embodiment, among others, a method for metal-assisted chemical etching includes providing a substrate; depositing a non-spherical metal catalyst on a surface of the substrate; etching the substrate by exposing the non-spherical metal catalyst and the substrate to an etchant solution including a composition of a fluoride etchant and an oxidizing agent; and removing the etched substrate from the etchant solution.
US08278190B2 Methods of forming light-emitting structures
Methods of forming light-emitting structures, as well as related devices and/or systems are described. In some cases, the methods utilize a layer transfer and/or layer separation step(s) used to form such structures.
US08278189B2 Method for thinning wafer
The present invention provides a method of thinning a wafer. First, a wafer is provided. The wafer includes an active surface, a back surface and a side surface. The active surface is disposed opposite to the back surface. The side surface is disposed between the active surface and the back surface and encompasses the peripheral of the wafer. Next, a protective structure is formed on the wafer to at least completely cover the side surface. Last, a thinning process is performed upon the wafer from the back surface.
US08278186B2 Wafer cleaning method and wafer bonding method using the same
The present invention relates to a wafer cleaning and a wafer bonding method using the same that can improve a yield of cleaning process and bonding property in bonding the cleaned wafer by cleaning the wafer using atmospheric pressure plasma and cleaning solution. The wafer cleaning method includes the steps of providing a process chamber with a wafer whose bonding surface faces upward, cleaning and surface-treating the bonding surface of the wafer by supplying atmospheric pressure plasma and a cleaning solution to the bonding surface of the wafer, and withdrawing out the wafer from the process chamber. The wafer bonding method includes the steps of: providing a first process chamber with a first wafer whose bonding surface faces upward; cleaning and surface-treating the bonding surface of the first wafer by supplying atmospheric pressure plasma and a cleaning solution to the bonding surface of the first wafer; withdrawing out the first wafer from the first process chamber and providing a second process chamber with the first wafer; providing a third process chamber with a second wafer whose bonding surface faces upward; cleaning and surface-treating the bonding surface of the second wafer by supplying atmospheric pressure plasma and a cleaning solution to the bonding surface of the second wafer; withdrawing out the second wafer from the third process chamber and providing the second process chamber with the second wafer whose bonding surface faces to the bonding surface of the first wafer and bonding the bonding surfaces of the first and second wafers to each other.
US08278185B2 Method for forming device isolation layer of semiconductor device and non-volatile memory device
A method for forming a device isolation layer of a semiconductor device or a non-volatile memory device is provided. A method for forming a device isolation layer of a semiconductor device includes: forming trenches having a first predetermined depth by etching a substrate; forming a first insulation layer having a second predetermined depth inside the trenches; forming a liner oxide layer having a predetermined thickness on internal walls of the trenches with the first insulation layer formed therein; and forming a second insulation layer for forming a device isolation layer over the substrate with the liner oxide layer formed therein, wherein the second insulation layer has a lower etch rate than that of the first insulation layer.
US08278184B1 Fabrication method of a non-planar transistor
A method of forming a non-planar transistor is provided. A substrate is provided. The substrate has a plurality of isolation regions to be formed and a plurality of fin regions to be formed. A first etching process is performed to form a plurality of first trenches having a first depth in the substrate within the isolation regions. At least a doping region is formed in the substrate within the fin regions. A second etching process is performed to deepen the first depth to a second depth and a plurality of fin structures are formed in the substrate within the fin regions. Lastly, a gate is formed on the fin structures.
US08278183B2 Production of isolation trenches with different sidewall dopings
A description is given of a method for producing isolation trenches (32, 34) with different sidewall dopings on a silicon-based substrate wafer for use in the trench-isolated smart power technology. In this case, a first trench (32) having a first width and a second trench (34) having a second width which is greater than the first width are formed using a hard mask (30). The sidewalls of the first and second trenches are doped in accordance with a first doping type in order to produce sidewalls having a first doping. A material layer (50, 51, 60, 61) is deposited with a thickness determined so as to fill the first trench (32) completely up to and beyond the hard mask and to maintain the gap (34a) in the second trench (34). By means of isotropic etching the material layer is removed from the second trench, but residual material of the material layer is maintained in the first trench. A further doping of sidewalls of the first trench or of the second trench in the presence of the residual material is then performed.
US08278178B2 Nonvolatile memory device and method of manufacturing the same
A method of manufacturing a nonvolatile memory device wherein first gate lines and second gate lines are formed over a semiconductor substrate. The first gate lines are spaced-from each other at a first width, the second gate lines are spaced-from each other at a second width, and the first width is wider than the second width. A first ion implantation process of forming first junction regions in the semiconductor substrate between the first gate lines and the second gate lines is performed. A second ion implantation process of forming second junction regions in the respective first junction regions between the first gate lines is then performed.
US08278175B2 Compressively stressed FET device structures
Methods for fabricating FET device structures are disclosed. The methods include receiving a fin of a Si based material, and converting a region of the fin into an oxide element. The oxide element exerts pressure onto the fin where a Fin-FET device is fabricated. The exerted pressure induces compressive stress in the device channel of the Fin-FET device. The methods also include receiving a rectangular member of a Si based material and converting a region of the member into an oxide element. The methods further include patterning the member that N fins are formed in parallel, while being abutted by the oxide element, which exerts pressure onto the N fins. Fin-FET devices are fabricated in the compressed fins, which results in compressively stressed device channels. FET devices structures are also disclosed. An FET devices structure has a Fin-FET device with a fin of a Si based material. An oxide element is abutting the fin and exerts pressure onto the fin. The Fin-FET device channel is compressively stressed due to the pressure on the fin. A further FET device structure has Fin-FET devices in a row each having fins. An oxide element extending perpendicularly to the row of fins is abutting the fins and exerts pressure onto the fins. Device channels of the Fin-FET devices are compressively stressed due to the pressure on the fins.
US08278174B2 In situ formed drain and source regions including a strain-inducing alloy and a graded dopant profile
The dopant profile of a transistor may be obtained on the basis of an in situ doped strain-inducing semiconductor alloy wherein a graded dopant concentration may be established along the height direction. Consequently, the semiconductor alloy may be positioned in close proximity to the channel region, thereby enhancing the overall strain-inducing efficiency, while not unduly compromising the finally obtained dopant profile. Furthermore, additional implant species may be incorporated prior to selectively growing the semiconductor alloy, thereby avoiding implantation-induced relaxation of the internal strain.
US08278171B2 Fabrication method for semiconductor device having laminated electronic conductor on bit line
There are provided a semiconductor device and a fabrication method therefor including an ONO film (18) formed on a semiconductor substrate (10), a word line (24) formed on the ONO film (18), a bit line (20) formed in the semiconductor substrate (10), and a conductive layer (32) that is in contact with the bit line (20), runs in a length direction of the bit line (20), and includes a polysilicon layer or a metal layer. In accordance with the present invention, a semiconductor device and a fabrication method therefor are provided wherein degradation of the writing and erasing characteristics and degradation of the transistor characteristics such as a junction leakage are suppressed, and the bit line resistance is decreased.
US08278165B2 Methods for protecting film layers while removing hardmasks during fabrication of semiconductor devices
Methods for fabricating semiconductor devices are provided. The methods include providing a semiconductor substrate having pFET and nFET regions, each having active areas and shallow trench isolation. A hardmask layer is formed overlying the semiconductor substrate. A photoresist layer is provided over the hardmask layer. The phoresist layer is patterned. An exposed portion of the hardmask layer is removed from one of the pFET region and nFET region with the patterned photoresist acting as an etch mask to define a masked region and an unmasked region. An epitaxial silicon layer is formed on the active area in the unmasked region. A protective oxide layer is formed overlying the epitaxial silicon layer. The hardmask layer is removed from the masked region with the protective oxide layer protecting the epitaxial silicon layer during such removal step. The protective oxide layer is removed from the epitaxial silicon layer.
US08278162B2 Method for manufacturing semiconductor device
A formation of a gate electrode provided over an oxide semiconductor layer of a thin film transistor is performed together with a patterning of the oxide semiconductor layer.
US08278161B2 Method for fabricating a thin film transistor array substrate with a thinned protective film over a storage capacitor
A thin film transistor array substrate and a fabricating method are disclosed. A gate line and a data line cross each other and a thin film transistor (TFT) is provided at the intersection between the gate and data lines. A protective film covers the data line and the thin film transistor and has a contact hole exposing a drain electrode of the TFT. A pixel electrode is connected, via the contact hole, to the drain electrode of the TFT. A storage capacitor includes a gate insulating film between the pixel electrode and the gate line and/or a common line. Some or all of the protective film within the storage capacitor is removed such that the storage capacitor contains no protective film or a layer of protective film that is thinner than the portion covering the TFT.
US08278160B2 Semiconductor device and method of manufacturing the same
A semiconductor device with high reliability and operation performance is manufactured without increasing the number of manufacture steps. A gate electrode has a laminate structure. A TFT having a low concentration impurity region that overlaps the gate electrode or a TFT having a low concentration impurity region that does not overlap the gate electrode is chosen for a circuit in accordance with the function of the circuit.
US08278154B2 Method of fabricating a semiconductor device package including a heat radiation plate
A semiconductor device package includes a semiconductor chip including a conductive pad, a die pad on which the semiconductor chip is mounted and having a first thickness, a lead pattern including a first portion disposed adjacent to the edge of the die pad and having the first thickness and a second portion having a second thickness greater than the first thickness, a heat radiation member disposed on the die pad and the lead pattern and including a groove formed at its bottom surface, and a conductive line disposed to electrically connect the conductive pad to the lead pattern corresponding to the conductive pad and partially inserted into the groove.
US08278152B2 Bonding process for CMOS image sensor
The present disclosure provides a method of making an integrated circuit (IC). The method includes forming an electric device on a front side of a substrate; forming a top metal pad on the front side of the substrate, the top metal pad being coupled to the electric device; forming a passivation layer on the front side of the substrate, the top metal pad being embedded in the passivation layer; forming an opening in the passivation layer, exposing the top metal pad; forming a deep trench in the substrate; filling a conductive material in the deep trench and the opening, resulting in a though-wafer via (TWV) feature in the deep trench and a pad-TWV feature in the opening, where the top metal pad being connected to the TWV feature through the pad-TWV feature; and applying a polishing process to remove excessive conductive material, forming a substantially planar surface.
US08278150B2 Stackable packages for three-dimensional packaging of semiconductor dice
An apparatus and a method for packaging semiconductor devices. The apparatus includes a substrate strip component of a leadless three-dimensional stackable semiconductor package having mounting contacts on, for example, four peripheral edges. The substrate strip may either be fabricated for mounting a single electrical component (e.g., an integrated circuit die) or a plurality of substrate strips may be laid out in an X-Y matrix pattern which may later be singulated into individual package strip for leadless packages. Three-dimensional stacking is achieved by a bonding area on an uppermost portion of the sidewall. The sidewall of the strip is high enough to enclose an encapsulant covering a later mounted integrated circuit die and associated bonding wires.
US08278149B2 Package with multiple dies
A semiconductor die package is disclosed. It includes a leadframe structure comprising a first die attach pad and a second die attach pad. A plurality of leads extend from the first and second die attach pads. The plurality of leads includes at least a first control lead and a second control lead. A first semiconductor die including a first device is mounted on the first die attach pad, and a second semiconductor die has a second device is mounted on the second die attach pad. A housing is provided in the semiconductor die package and protects the first and second dies. The housing may have an exterior surface and at least partially covers the first semiconductor die and the second semiconductor die. The first control lead and the second control lead are at opposite sides of the semiconductor die package.
US08278146B2 Manufacturing method of chip package with coplanarity controlling feature
A chip package includes a substrate, an integrated circuit proximate a top surface of the substrate, and a cap comprising encapsulant that encapsulates the integrated circuit on at least a portion of the top surface of the substrate. The chip package further includes at least one extension feature positioned on at least a portion of the top surface of the substrate. The at least one extension feature also comprises the encapsulant and extends from the cap to a perimeter of the substrate.
US08278132B2 Image sensor and fabricating method thereof
The present invention provides an image sensor and a fabricating method thereof capable of approaching higher quantum efficiency and reducing cost. The method comprises: providing a substrate; forming a pixel region on a top surface of the substrate; forming an interlayer insulating layer and at least a metal line on the pixel region; forming an isolation carrier layer having a hole array therein on the interlayer insulating layer; grinding a lower surface of the substrate to reduce the thickness of the substrate; placing a plurality of conductors into the hole array to form a plurality of bumps on the isolation carrier layer.
US08278120B2 Method of changing fluorescence wavelength of fluorescent protein
The present invention provides: a method of changing the fluorescence wavelength of a GFP-like fluorescent protein from copepod while maintaining recombinant expression efficiency, which comprises identifying a structural factor for determining the fluorescence wavelength thereof in the three-dimensional structure of the protein and modifying amino acid residues associated with the structural factor; and a modified fluorescent protein obtained by applying said method. For example, with regard to a GFP-like fluorescent protein from Chiridius poppei, His52 in an α helix-like secondary structure: PFLLSHCMGYGFYHF (α1 47-61) comprising a fluorescent moiety site GYG is replaced with an aromatic amino acid selected from Phe, Tyr and Trp, so as to cause a red shift of the fluorescent peak wavelength; or it is replaced with Ala, Val, Ile, Leu, Gly, Cys, Met, Ser, Thr, or Asp, Asn, Glu or Gln, so as to cause a blue shift of the fluorescence peak wavelength.
US08278114B2 Method for measuring luminescence at a luminescence detection workstation
A luminescence detecting apparatus and method for analyzing luminescent samples is disclosed. A detecting apparatus may be configured so that light from luminescent samples pass through a collimator, a a first lens, a filter, and a camera lens, whereupon an image is created by the optics on the charge-coupled device (CCD) camera. The detecting apparatus may further include central processing control of all operations, multiple wavelength filter wheel, and/or a robot for handling of samples and reagents.
US08278110B2 Method and a blood oxygen tester for detecting the arterial or venous blood
A method and a blood oxygen tester for determining whether a blood sample is arterial or venous blood are disclosed. A blood oxygen tester for determining whether a blood sample is arterial or venous blood includes a housing and a blood sample receptacle defined by the housing. A blood oxygen sensor is in communication with the blood sample receptacle and a test result indicator is in communication with the blood oxygen sensor. The indicator is responsive to the blood oxygen sensor for indicating whether a tested blood sample is arterial blood or venous blood.
US08278109B2 Hyperglycosylated hCG detection device
The present invention related to a pregnancy test device that can selectively detect hyperglycosylated human chorionic gonadotropin (hCG-H) in a liquid sample. The sample can be deposited on a proximal portion of the device for transport to a distal portion of the device. The device can include a release medium formed of a first material and including a detectable label thereon and a capture medium, including a capture site, in fluid communication with the release medium and formed of a second, different material. At least one of the release medium and the capture medium includes a binding member that exhibits a moderate to high affinity for hCG-H and is selectively or preferentially reactive with hCG-H.
US08278108B2 Automatic analyzer
An automatic analyzer of the type equipped with a sample preprocessing function pretreats a desired sample in a pretreating unit before pipetting the sample into an analyzing unit for analysis. When all samples are carried to the analyzing unit via the pretreating unit, irrespective of whether the sample is to be pretreated, this causes loss in terms of both costs and installation space requirements. In the case where the preprocessing is required, a minimal quantity of the sample is also necessary in order to make the sample react to the preprocessing liquid. In addition, the possible presence of a residual sample left in the pretreating unit could affect analytical results. The automatic analyzer which includes an analyzing unit and a pretreating unit further includes a sample-pipetting mechanism constructed to have a function that allows the mechanism to access a plurality of pipetting positions without a sample sucking/discharging position being fixed.
US08278107B2 Compositions and methods for regulating RNA translation via CD154 CA-dinucleotide repeat
Compositions and methods for regulating CD154 gene expression are provided that rely on the interaction of hnRNP L with the CA-dinucleotide rich sequence of the 3′-untranslated region of CD154.
US08278103B2 Oligonucleotides comprising alternating segments and uses thereof
The invention relates to oligonucleosides having alternating segments of sugar-modified nucleosides and 2′-deoxynucleosides, and uses thereof. The invention further relates to oligonucleotides having alternating segments of sugar-modified nucleotides and 2′-deoxynucleotides, and uses thereof. Such uses include the preparation of antisense oligonucleotides and their use for the prevention or depletion of function of a target nucleic acid of interest, such as an RNA, in a system. Accordingly, an oligonucleotide of the invention is useful for therapeutic, analytical and diagnostic methods and uses, as well as a component of compositions and commercial packages corresponding to such methods and uses.
US08278101B2 Stem cell bioprocessing and cell expansion
A stem cell niche for expanding stem cells in culture is described. The stem cell niche includes a scaffold, a plurality of stromal mesenchymal stem cells, and a plurality of umbilical cord blood stem cells grown in a rotating culture chamber. One embodiment of the rotating culture chamber has a fluid-filled compartment in which the umbilical cord blood stem cells are grown in the presence of the mesenchymal stem cells seeded on the scaffold. The culture chamber has a dual flow valving member at each end, wherein a first flow path passes under a molecular cut-off membrane covering a central core that transverses the culture chamber and a second flow path flows through the culture chamber and allows cells to be harvested while in suspension.
US08278099B1 Monoclonal antibody to human thrombopoietin
Isolated thrombopoietin (TPO), isolated DNA encoding TPO, and recombinant or synthetic methods of preparing and purifying TPO are disclosed. Various forms of TPO are shown to influence the replication, differentiation or maturation of blood cells, especially megakaryocytes and megakaryocyte progenitor cells. Accordingly, these compounds may be used for treatment of thrombocytopenia.
US08278097B2 Method for forming embryoid bodies
The invention relates to a vessel for embryoid formation used for forming embryoid bodies from ES cells easily without complicated technique, and to a method for forming embryoid bodies easily and efficiently using the vessel. The method includes the steps of (A) providing a vessel for embryoid formation having a coating layer formed from a compound having a particular PC-like group on a vessel surface defining a region for floating culture of ES cells, and (B) floating culturing ES cells in the vessel to form embryoid bodies.
US08278090B1 Heterotrophic cultivation of hydrocarbon-producing microalgae
The invention discloses novel methods of producing hydrocarbons through heterotrophic cultivation of Botryococcus braunii. Also provided are novel hydrocarbon compositions. A preferred species for engineering is the microalgae species Botryococcus braunii. Additional methods of cultivation include providing certain nutrient sources.
US08278087B2 Energy production with hyperthermophilic organisms
The present invention relates to the field of degradation with hyperthermophilic organisms, and in particular to the use of hyperthermophilic degradation to produce heat and energy rich components including hydrogen and ethanol from a biomass. In some embodiments, a biomass is fermented in the presence of hyperthermophilic organisms to produce heat. The heat is used to heat a liquid which is used directly in a heat pump or radiant heat or to produce electricity or drive a steam turbine. In some embodiments, acetate is utilized as a substrate to produce energy by methanogenesis.
US08278085B2 RNA processing protein complexes and uses thereof
The invention provides human protein complexes with endonuclease activity, including tRNA splicing endonuclease activity and 3′ end pre-mRNA endonuclease activity, and pre-ribosomal RNA cleavage activity. The invention also provides a splice variant of human Sen2, and human protein complexes comprising the variant. The invention provides human protein complexes with pre-ribosomal RNA cleavage activity. The invention also provides antibodies that immunospecifically bind to a complex described herein or a component thereof, and uses of such antibodies. The present invention also provides methods of preparing and purifying the complexes and uses of the complexes inter alia, in screening, diagnosis, and therapy. The present invention further provides methods of identifying a compound that modulates the expression of a component of a complex described herein, the formation of a complex described herein or the activity of a complex described herein, and methods of preventing, treating, managing or ameliorating a disorder, such as a proliferative disorder, or a symptom thereof utilizing such a compound.
US08278084B2 Aminopyridine dimer compounds, compositions and related methods for neuronal nitric oxide synthase inhibition
Nitric oxide synthase (NOS) inhibitor compounds comprising bi-terminal aromatic ring moieties, and related methods of NOS inhibition.
US08278083B2 Inactivated influenza virus compositions
The invention provides compositions of inactivated influenza virus that can be used as vaccines and immunological compositions useful for inhibiting, preventing and treating influenza.
US08278080B2 Method for pretreating biomass to produce bioethanol
Disclosed is a method for preparing bioethanol from biomass. The feedstock for preparation of bioethanol, i.e. the biomass, is pretreated by a combination of chemical and physical methods. The method is advantageous in that detoxification is unnecessary since the substances that inhibit fermentation are not produced and acid reconcentration for recycling is not needed. Further, since the sonication makes saccharification easier, removal of lignin (delignification), which interferes with the saccharification of cellulose, is unnecessary. Accordingly, the present disclosure allows to produce bioethanol with high yield and at low cost in an environment-friendly manner.
US08278077B2 Enzymatic production of (meth)acrylic acid esters
The present invention relates to a process for preparing (meth)acrylic esters of alcohols having C—C triple bonds, to processes for their preparation, and to their use.
US08278071B2 Method for detecting the presence of a single target nucleic acid in a sample
A method comprising subjecting one or more sample portion(s) to a single amplification step, thereby amplifying a single molecule in the sample portion to a detectable level, and, in some embodiments, then determining whether the sample portion contains at least one molecule of the target nucleic acid. In some embodiments, the sample portion is in a porous sample structure, or in a sample chamber which comprises means for minimizing diffusion of the sample portion, or in a sample chamber which is inside a microcapillary device, or in a sample retaining means.
US08278069B2 Identification of a β-1,3-N-acetylgalactosaminyltransferase (CGTE) from Campylobacter jejuni LIO87
The invention relates to β-1,3-N-acetylgalactosaminyltransferase polypeptides, nucleic acids that encode the polypeptides, and methods of using the polypeptides.
US08278066B2 Truncated somatostatin receptors
The present invention is directed to fusion proteins that can be used to assay gene transfer and expression both in vitro and in vivo. The fusion proteins contain a reporter protein, e.g. a somatostatin receptor, fused to a second protein, which may be a protein fusion tag. Alternatively, a fusion protein may be fused to a leader sequence. A leader sequence may localize an expressed protein, e.g. localize a fusion protein to the cell membrane. The invention includes nucleic acids encoding the fusion proteins and methods of assaying for gene expression.
US08278059B2 Methods and systems of using exosomes for determining phenotypes
Exosomes can be used for detecting biomarkers for diagnostic, therapy-related or prognostic methods to identify phenotypes, such as a condition or disease, for example, the stage or progression of a disease. Cell-of-origin exosomes can be used in profiling of physiological states or determining phenotypes. Biomarkers or markers from cell-of-origin specific exosomes can be used to determine treatment regimens for diseases, conditions, disease stages, and stages of a condition, and can also be used to determine treatment efficacy. Markers from cell-of-origin specific exosomes can also be used to identify conditions of diseases of unknown origin.
US08278056B2 Detection of early stages and late stages HPV infection
Embodiments of the invention provide methods, monoclonal antibodies, polyclonal antibodies, assays, and kits for detecting HPV infection and HPV related cancer diagnosis, including infection by various HPV genotypes, early and/or late stage HPV-associated or HPV-specific cancers. Various specific or pan monoclonal antibodies recognizing specific epitope for specific HPV protein or HPV type, or common epitope for various HPV proteins or HPV types are obtained. The invention also provides one or more solid surface to coat the testing cell lysate. Also, the anti-HPV antibody can be coated on the solid surface of the invention to capture HPV proteins and detect HPV infection.
US08278054B2 Diagnosis of metal allergy through cytokine release by T-cells in vitro
An in vitro method for diagnosing a contact allergy in a subject comprises: (i) providing (a) a contact allergen; (b) T-cells from said subject; and (c) a surface to which is immobilized a first specific binding agent capable of specifically binding to a cytokine released from a T-cell in response to said allergen; (ii) contacting said sample with said allergen under conditions which are suitable for (a) release of said cytokine by T cells that have been presensitized in vivo to said allergen; and (b) binding of said cytokine to said first specific binding agent; and (iii) detecting binding of said substance to said first specific binding agent. A kit which enables the method to be carried out is also described.
US08278052B2 Tagged oligonucleotides and their use in nucleic acid amplification methods
The present invention provides kits containing tagged oligonucleotides for use in certain nucleic acid amplification methods to desirably reduce or eliminate false positive amplification signals resulting from contaminating biological material, e.g., nucleic acid, that may be present in one or more reagents used in an amplification reaction and/or that may be present in the environment in which an amplification reaction is performed. The kits containing tagged oligonucleotides can be used in purification and/or sterility efforts under less stringent conditions than conventionally needed to reduce or eliminate false positive results in a nucleic acid amplification method.
US08278050B2 Detection of chromosomal inversions using non-repetitive nucleic acid probes
A method for the identification of chromosomal inversions is described. Single-stranded sister chromatids are generated, for example by CO-FISH. A plurality of non-repetitive, labeled probes of relatively small size are hybridized to portions of only one of a pair of single-stranded sister chromatids. If no inversion exists, all of the probes will hybridize to a first chromatid. If an inversion has occurred, these marker probes will be detected on the sister chromatid at the same location as the inversion on the first chromatid.
US08278044B2 Method for the identification of carcinogenic compounds
The present invention relates to methods for the identification of genotoxic carcinogenic compounds. In particular, a method is disclosed for the identification of genotoxic carcinogenic compounds wherein a eukaryotic cell is exposed to a potentially genotoxic compound in a culture medium where after samples are taken from the cell and/or the culture medium at least one predetermined time point which samples are then analysed for increased or decreased expression levels of at least three DNA repair genes as compared to a control cell that is not exposed to the carcinogenic compound.
US08278043B2 Methods and materials related to grey alleles
This document relates to methods and materials for determining whether or not a horse contains a Grey allele. For example, diagnostic methods such as nucleic acid-based detection methods and materials such as nucleic acid probes and primer pairs that can be used to determine whether or not a horse contains a duplication in intron 6 of STX17 nucleic acid are provided. This document also relates to methods and materials for treating a mammal having or being likely to develop cancer (e.g., benign, malignant, or metastatic cancer). For example, methods and materials for treating cancer in a mammal by administering an agent having the ability to reduce expression of an STX17 polypeptide and/or an NR4A polypeptide (e.g., an NR4A1, NR4A2, or NR4A3 polypeptide) in the mammal are provided.
US08278042B2 Compositions and methods for the diagnosis and treatment of tumor
The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
US08278040B2 Optically responsive and mechanically tunable colloid-in-liquid crystal gels
Colloidal liquid crystal gels (CLCGs), sensors incorporating the CLCGs, culture substrates made from the CLCGs, and patterned films and molded articles made from the CLCGs are provided. The CLCGs are composite liquid crystal materials comprising networks of particles having liquid crystal domains dispersed therein.
US08278036B2 RNA containing modified nucleosides and methods of use thereof
This invention provides RNA, oligoribonucleotide, and polyribonucleotide molecules comprising pseudouridine or a modified nucleoside, gene therapy vectors comprising same, methods of synthesizing same, and methods for gene replacement, gene therapy, gene transcription silencing, and the delivery of therapeutic proteins to tissue in vivo, comprising the molecules. The present invention also provides methods of reducing the immunogenicity of RNA, oligoribonucleotide, and polyribonucleotide molecules.
US08278035B2 Method and substances for isolating miRNAs
A capture probe suitable for use with a method for isolating miRNAs. A method for isolating an miRNA of interest from a sample comprising the miRNA of interest comprising providing the capture probe. A method for identifying an miRNA of interest.
US08278033B2 Efficient well being assessment and improved treatment protocol
Methods to appraise general health and to assess the effectiveness of therapeutic agents are disclosed. These methods can be performed on blood samples or other bodily fluids and comprise effecting cell death of endothelial cells, staining the dead cells and observing them microscopically. In addition, the invention is directed to combination treatments for neoplastic diseases or other conditions characterized by unwanted angiogenesis by administering an antiangiogenesis agent while maintaining nontoxic levels of ethanol and/or DMSO in the blood.
US08278029B2 Stamper production method and read-only optical disc production method
A stamper production method includes: a stamper forming step of producing, by electroplating processing using a matrix in which a pit string constituted of a concave pit is formed on an inorganic resist layer based on recording information, a stamper on which a convex pit corresponding to the concave pit is formed; and an etching step of carrying out etching processing on the stamper so that a reduction ratio of a pit height of a short pit becomes larger than that of a long pit regarding the convex pit of the stamper.
US08278027B2 Apparatus and method for conformal mask manufacturing
A manufacturing process technology creates a pattern on a first layer using a focused ion beam process. The pattern is transferred to a second layer, which may act as a traditional etch stop layer. The pattern can be formed on the second layer without irradiation by light through a reticle and without wet chemical developing, thereby enabling conformal coverage and very fine critical feature control. Both dark field patterns and light field patterns are disclosed, which may enable reduced or minimal exposure by the focused ion beam.
US08278022B2 Positive resist composition and method of forming resist pattern
Provided are a novel positive resist composition that includes a low molecular weight material as a base material component, and a method of forming a resist pattern using the positive resist composition.A positive resist composition including: a base material component (A) that exhibits increased solubility in an alkali developing solution under the action of acid; and an acid generator component (B) that generates acid upon exposure, wherein the base material component (A) comprises a compound (A1) in which either a portion of, or all of, the hydrogen atoms of hydroxyl groups (—OH) within a phenolic compound (I) described below have been substituted with a group containing an acid dissociable, dissolution inhibiting group: the phenolic compound (I) including 4 triphenylmethane structures, and a tetravalent linking moiety that links the 4 triphenylmethane structures, wherein at least one of the 4 triphenylmethane structures has at least one phenolic hydroxyl group.
US08278019B2 Method of manufacturing electrostatic charge image developing toner
Provided is a method of manufacturing an electrostatic charge image developing toner exhibiting reduced variation in charging amount among manufacturing lots, which is capable of generating no fog, and acquiring high density print images. Disclosed is a method of manufacturing an electrostatic charge image developing toner, possessing the step of washing toner mother particles having been formed in an aqueous medium with washing water, wherein the washing water has a total dissolution component amount of at least 0.05 mg/liter and less than 0.5 mg/liter.
US08278018B2 Process for producing dry ink colorants that will reduce metamerism
In accordance with the invention, there is a method of forming a toner. The method can include blending two or more colorants to form a sample toner and forming a sample color specimen including a printed image comprising the sample toner. The method can further include comparing spectral distribution curves of the sample color specimen with that of a target color specimen including a target color and repeating the disclosed steps until acquiring a desired spectral match between the sample toner and the target color.
US08278015B2 Charge transport layer comprising anti-oxidants
The presently disclosed embodiments are directed generally to an improved electrostatographic imaging member incorporating specific anti-oxidants into the charge transport layer to achieve substantially reduced lateral charge migration. The imaging members having such an charge transport layer can include charge transport molecules such as N,N,N,′N′-tetra(4-methylphenyl)-(1,1′-biphenyl)-4,4′-diamine without increased sensitivity to corona-induced lateral charge migration.
US08278014B2 Photomask and pattern formation method using the same
A photomask includes a transparent substrate having a transparent property against exposing light, a semi-light-shielding portion formed on the transparent substrate, a first opening formed in the semi-light-shielding portion and having a first dimension and a second opening formed in the semi-light-shielding portion and having a second dimension lager than the first dimension. A phase-shifting portion which transmits the exposing light in an opposite phase with respect to the first opening is formed on the transparent substrate around the first opening. A light-shielding portion is formed on the transparent substrate around the second opening.
US08278013B2 Fuel cell device and system
The present invention relates to fuel cell devices and fuel cell systems, methods of using fuel cell devices and systems, and methods of making fuel cell devices. According to certain embodiments, the fuel cell devices may include an elongate substrate, such as a rectangular or tubular substrate, the length of which is the greatest dimension such that the coefficient of thermal expansion has only one dominant axis that is coextensive with the length. In addition, or in accordance with other certain embodiments, a reaction zone is positioned along a first portion of the length for heating to an operating reaction temperature, and at least one cold zone is positioned along a second portion of the length for operating at a temperature below the operating reaction temperature. There are one or more fuel passages in the elongate substrate, each having an associate anode, and one or more oxidizer passages in the elongate substrate, each having an associate cathode. In some embodiments, the passages are formed by sacrificial organic materials that are melted or baked out of the structure and/or by removable structures that are pulled out after lamination. Bake-out paths may also be used to facilitate removal of the sacrificial organic materials, which paths are later sealed. Embodiments of the invention further include methods and devices in which a current collector is recessed into the electrode.
US08278011B2 Nanostructured catalyst supports
The present invention relates to SiC nanostructures, including SiC nanopowder, SiC nanowires, and composites of SiC nanopowder and nanowires, which can be used as catalyst supports in membrane electrode assemblies and in fuel cells. The present invention also relates to composite catalyst supports comprising nanopowder and one or more inorganic nanowires for a membrane electrode assembly.
US08278010B2 Carbon nanotube electrode comprising sulfur or metal nanoparticles as a binder and process for preparing the same
The present invention provides an electrode made of carbon nanotubes or carbon nanofibers and a process for preparing the same. The electrode comprising a current collector, sulfur or metal nanoparticles as a binder, and carbon nanotubes or carbon nanofibers is characterized in that the sulfur or metal nanoparticles are bonded, deposited, or fused on the surfaces of the carbon nanotubes or carbon nanofibers so that the carbon nanotubes or carbon nanofibers are bonded to each other and also bonded to the current collector. The electrode prepared according to the present invention exhibits low internal resistance, strong durability and low equivalent series resistance, and therefore the electrode can be effectively used for secondary batteries, supercapacitors or fuel cells.
US08278009B2 Metallic material for conductive member, separator for fuel cell using the same, and fuel cell using the separator
A metallic material for a conductive member has good corrosion resistance and low contact resistance. The metallic material has 0.3 μm or less of mean spacing of local peaks of the surface roughness profile. A proton-exchange membrane fuel cell includes a proton-exchange membrane, an electrode, a gas diffusing layer, and a separator using the metallic material for a conductive member, where the metallic material for a conductive member includes a stainless steel and includes 0.03% or less C, 0.03% or less N, 16 to 45% Cr, 0.1 to 5.0% Mo, 0.03% or less (C+N), by mass, and balance of Fe and inevitable impurities, and where the metallic material for a conductive member has 0.3 μm or less of mean spacing of local peaks of the surface roughness profile.
US08278008B2 Serpentine fuel cell separator with protrusions and fuel cell including the same
A fuel cell separator and a fuel cell are provided that can improve uniformity in reaction gas flow rate and can prevent flooding due to excessive condensed water in passage grooves appropriately. A reaction gas passage region (101) of a separator (2) has a flow splitting region (21) having a passage groove group where the reaction gas is split, and one or more flow merge regions (22) having a recessed portion in which the reaction gas is mixed and connecting a plurality of flow splitting regions so that the passage groove group of the adjacent flow splitting regions (21) are connected to the recessed portion, and protrusions (27) vertically extend from a bottom face of the recessed portion and arranged in an island form. A pair of passage groove groups connected to the recessed portion of the flow merge region (22) is formed so as to have a greater number of grooves in the upstream passage groove group than the number of grooves of grooves in the downstream passage groove group. The recessed portion of the flow merge region (22) is defined, in a turn portion of a serpentine shaped reaction gas passage region (101), by oblique boundaries between the recessed portion and a pair of passage groove groups which are connected to the recessed portion and by the outer end of the turn portion.
US08278006B2 Fuel cell system and mobile communication device including the same
A fuel cell system includes: a cell pack including an anode layer, a cathode layer, and an electrolyte; a fuel tank separated from the cell pack, and having a hole; a fuel mixture unit connected to the cell pack; a fuel storage medium included in the fuel tank, and a part of which is exposed through the hole; and a fuel supplying path having a first end connected to the fuel mixture unit, and a second end connected to the fuel storage medium only when the fuel cell system operates. A mobile communication device includes the fuel cell system.
US08278005B2 Separator for fuel cell and solid polymer type fuel cell
Notches 23e are filled with part of an elastic material that is injection-molded in a region containing the notches 23e, so that a plate member 23b is taken in by the notches 23e through the repulsive force of the elastic material. Thus, the plate member 23b is secured. Further, the elastic material filling the notches 23e enlarges the joined portion between the plate member 23b and the gasket 24b. Accordingly, the gasket 24b is firmly joined to the surface of the plate member 23b, and can be prevented from being lifted up from the plate member 23b. Thus, the plate member 23b is firmly secured to the separator main body 25.
US08278003B2 Direct methanol fuel cell
According to one embodiment, a direct methanol fuel cell includes an anode to which an aqueous methanol solution is supplied as the fuel, a cathode to which oxidizing gas is supplied, an electrolyte membrane interposed between the anode and the cathode, a first separator disposed on the surface of the anode on the side opposite to the electrolyte membrane side and a second separator disposed on the surface of the cathode on the side opposite to the electrolyte membrane side, wherein the first and second separators are respectively made of a membrane containing a copolymer of a first vinyl monomer having a cyclic functional group bonded with a carbonyl group, a second vinyl monomer having a carboxyl group and a third vinyl monomer having an aromatic group, and a carbon powder dispersed in the copolymer.
US08278002B2 Fuel-cell and fuel cell system including the same
A fuel cell includes: cells (11), each of which includes an electrolyte layer-electrode stack assembly (5) having a electrolyte layer (1) and a pair of gas diffusion electrodes (4a, 4b) sandwiching a portion of the electrolyte layer (1) which portion is located on an inner side of a peripheral portion of the electrolyte layer (1), an annular peripheral member disposed at the peripheral portion of the electrolyte layer (1), a pair of electrically conductive separators (6A, 6B) which sandwich the electrolyte layer-electrode stack assembly (5) and the peripheral member, and damage detecting wires (31); and a fuel cell stack (100) formed by stacking the cells (11), wherein: the damage detecting wires (31) are formed on components constituting the cell (11) other than the electrolyte layer-electrode stack assembly (5); and the damage detecting wires (31) are connected to one another to form an open circuit by stacking the cells (11).
US08278001B2 Low-porosity anode diffusion media for high concentration direct methanol fuel cells and method of making
A direct oxidation fuel cell (DOFC) having a liquid fuel and an anode electrode configured to generate power. The anode electrode includes a gas diffusion layer (GDL) and a microporous layer, such that a decrease in the porosity of the GDL achieves an increase in the power density of the DOFC.
US08277998B2 Water management in fuel cells
An electrochemical fuel cell having an anode, an ion transfer membrane and a cathode has liquid water delivered to the fluid flow channels within the cathode so as to maintain a relative humidity of 100% throughout the fluid flow channels. A calibration method and apparatus is described for determining an optimum quantity or range of quantities of liquid water to be delivered to the cathode fluid flow channels under varying operating conditions. An operating method and apparatus is described that ensures an optimum quantity of liquid water is delivered to the cathode fluid flow channels under varying operating conditions.
US08277995B2 Fuel cell power generation system
A fuel cell power generation system is disclosed. The fuel cell power generation system in accordance with an embodiment of the present invention includes: a stack, which produces electrical energy by reacting hydrogen with oxygen and in which the hydrogen is supplied as fuel and the oxygen is in the air; a hydrogen tank, which supplies fuel comprising hydrogen to the stack; and a heat transfer tape, which transfers heat generated from the stack to the hydrogen tank. The fuel cell power generation system can improve the efficiency of supplying hydrogen by supplying waste heat generated from the stack to the hydrogen tank through the use of the heat transfer tape without a heat supplying device and be applied to a mobile device due to the reduced volume of the fuel cell power generation system.
US08277993B2 Fuel cell system
A fuel cell system is provided which can accurately detect an insulation resistance even during a high-potential prevention control. The fuel cell system includes: a fuel cell that generates electric power through an electrochemical reaction between a fuel gas and an oxidant gas; an insulation resistance measurement unit that measures an insulation resistance between the fuel cell and an outer conductor; and a control unit that controls a power generation state of the fuel cell, and the control unit carries out a high-potential prevention control that avoids a voltage of the fuel cell becoming equal to or higher than a predetermined high-potential prevention voltage threshold lower than an open circuit voltage of the fuel cell, and changes the high-potential prevention voltage threshold during an insulation resistance detection performed by the insulation resistance measurement unit.
US08277987B2 Fuel cell system
A fuel cell system includes: a fuel cell stack configured to have a plurality of unit fuel cells arranged on an identical plane; a chassis configured to cover at least one side of said fuel cell stack via an air flow space; and a condensation water holding member configured to be provided in at least a part between said fuel cell stack and said chassis, have a mesh shape and have a function for keeping moisture.
US08277985B2 Separator including an elastic layer for use in humidifying device, humidifying device, and fuel cell system including humidifying device
A separator for use in a humidifying device includes: main surfaces contacting steam permeable membranes (2), respectively; a fluid channel (3, 4) formed by concave portions (66, 81) of a convex-concave portion formed on each of the main surfaces; and an elastic layer (1a, 1c) formed up to at least a certain depth from tip ends of convex portions (67, 82) of the convex-concave portion.
US08277983B2 Proton-conducting membrane and its use
The present invention relates to novel polyazoles, a proton-conducting polymer membrane based on these polyazoles and its use as polymer electrolyte membrane (PEM) for producing membrane-electrode units for PEM-fuel cells, and also other shaped bodies comprising such polyazoles.
US08277981B2 Secondary battery with improved storage characteristics and method for manufacturing the same
Provided is a secondary battery comprising a separator having an inorganic layer wherein active sites of inorganic particles in the inorganic layer are modified into non-reactive sites. Use of the separator leads to improvements in wettability of an electrolyte and thermoelectric stability and storage characteristics of the secondary battery. Provided is also a method of manufacturing the same secondary battery.
US08277979B2 Electrode composite material, method for making the same, and lithium ion battery using the same
An anode composite material includes an anode active material particle having a surface and a continuous aluminum phosphate layer. The continuous aluminum phosphate layer is coated on the surface of the anode active material particle. The present disclosure also relates to a lithium ion battery that includes the cathode composite material.
US08277976B2 Binder with good rate property and long cycleability for lithium secondary battery
Disclosed is a binder, which comprises polymer particles obtained by polymerization of: (a) 1˜80 parts by weight of a (meth)acrylic acid ester monomer; (b) 1˜20 parts by weight of an unsaturated carboxylic acid monomer; and (c) 0.001˜40 parts by weight of a vinyl monomer, based on 100 parts by weight of the binder polymer, and which allows electrode active material particles capable of lithium intercalation/deintercalation to be fixed and linked among themselves, and between the particles and a collector. An electrode comprising the binder, and a lithium secondary battery having the electrode are also disclosed. Further, a method for evaluating interrelation between wettability of a binder to an electrolyte and quality of a battery comprising the binder is disclosed. The binder shows excellent adhesion as well as excellent wettability to an electrolyte, and thus can improve rate characteristics and lifespan characteristics of a battery, when used in an electrode for a lithium secondary battery.
US08277974B2 High energy lithium ion batteries with particular negative electrode compositions
Combinations of materials are described in which high energy density active materials for negative electrodes of lithium ion batteries. In general, metal alloy/intermetallic compositions can provide the high energy density. These materials can have moderate volume changes upon cycling in a lithium ion battery. The volume changes can be accommodated with less degradation upon cycling through the combination with highly porous electrically conductive materials, such as highly porous carbon and/or foamed current collectors. Whether or not combined with a highly porous electrically conductive material, metal alloy/intermetallic compositions with an average particle size of no more than a micron can be advantageously used in the negative electrodes to improve cycling properties.
US08277971B2 Battery, charging apparatus and electronic device
In a battery including a battery cell formed in a flattened substantially parallelepiped shape and a terminal contacting section electrically connected to the battery cell, at one end in the longitudinal direction of a face of the battery opposing to the face on which the terminal contacting section is provided, a projecting portion which projects in the longitudinal direction of the face is provided. Meanwhile, another projecting portion which projects in the longitudinal direction of the face is provided at the other end. The projecting portions may have projecting lengths different from each other or may have projecting lengths and projecting thicknesses different from each other. A charging apparatus into which the battery is to be installed includes an accommodating section for the battery which in turn includes projection accommodating portions configured to individually accommodate the projecting portions.
US08277964B2 System and method for optimizing efficiency and power output from a vanadium redox battery energy storage system
An energy storage system includes a vanadium redox battery that interfaces with a control system to optimize performance and efficiency. The control system calculates optimal pump speeds, electrolyte temperature ranges, and charge and discharge rates. The control system instructs the vanadium redox battery to operate in accordance with the prescribed parameters. The control system further calculates optimal temperature ranges and charge and discharge rates for the vanadium redox battery.
US08277962B2 Magnetic recording medium for perpendicular magnetic recording
A perpendicular recording medium having a perpendicular magnetic recording layer and a magnetically soft underlayer structure disposed beneath the recording layer. The soft underlayer structure includes at least first and second soft magnetic layers having different magnetic permeabilities to create a magnetic permeability gradient in the soft underlayer structure. One or more of the soft magnetic layers can be anti-parallel coupled. The soft underlayer structure of the present invention having a magnetic permeability gradient advantageously leads to reduced adjacent track erasure (ATE) while maintaining good overwrite (OW) properties.
US08277961B2 Magnetic recording medium
A magnetic recording medium for thermally assisted recording is disclosed which achieves both high density writing and good control of temperature characteristics. The magnetic recording medium for thermally assisted recording comprises an underlayer, a magnetic recording layer, and a protective layer sequentially laminated on a nonmagnetic substrate. The magnetic recording layer has a structure composed of two magnetic layers and an exchange coupling control layer inserted between the magnetic layers, the two magnetic layers being magnetically coupled through the exchange coupling control layer. The coupling energy Jw in the process of writing a signal and the coupling energy Jr in the state of retaining a signal satisfy a relation 0
US08277957B2 Quinoxaline derivatives and organic light-emitting diodes comprising the same
A quinoxaline derivative represented by Formula (I) or (II) is provided. In Formula (I) or (II), R1 and R2 are, independently, hydrogen, halogen, methyl, ethyl, propyl, butyl, aryl or heteroaryl, for example phenyl, furyl, thienyl, pyridyl, pyrimidyl, benzothiazolyl or benzoimidazolyl. An organic light-emitting diode including the quinoxaline derivative is also provided.
US08277951B2 Device housing
A device housing is provided. The device housing includes a substrate, a barrier layer formed on the substrate, an illuminating layer formed on the barrier layer, and a protective layer formed on the illuminating layer. The barrier layer is made of titanium. The illuminating layer is made of rare-earth aluminates. The protective layer is made of silica dioxide. A method for making the device housing is also described there.
US08277946B2 Heat treatable coated article with diamond-like carbon (DLC) and/or zirconium in coating
In certain example embodiments, a coated article includes respective layers including hydrogenated diamond-like carbon (DLC) and zirconium nitride before heat treatment (HT). During HT, the hydrogenated DLC acts as a fuel which upon combustion with oxygen produces carbon dioxide and/or water. The high temperature developed during this combustion heats the zirconium nitride to a temperature(s) well above the heat treating temperature, thereby causing the zirconium nitride to be transformed into a new post-HT layer including zirconium oxide that is very scratch resistant and durable.
US08277945B2 Glass substrates coated or laminated with multiple layers of cured silicone resin compositions
An article of manufacture comprising (i) at least one glass substrate; (ii) a first coating layer on at least a portion of at least one side of the glass substrate wherein the first coating layer comprises an organic polymer or a cured silicone resin composition selected from a hydrosilylation cured silicone resin composition, a condensation cured silicone resin composition, or a free radical cured silicone resin composition; and (iii) a second coating layer on top of at least a portion of the first coating layer wherein the second coating layer comprises an organic polymer or a cured silicone resin composition selected from a hydrosilylation cured silicone resin composition, a condensation cured silicone resin composition, or a free radical cured silicone resin composition with the proviso that at least one of the first coating layer or the second coating layer comprises a cured silicone resin composition and with the proviso that when the first coating layer and second coating layer are both cured silicone resin compositions, the cured silicone resin composition of the first coating layer is different from the cured silicone resin composition of the second coating layer.
US08277943B2 Thin films with high near-infrared reflectivity deposited on building materials
Disclosed are solar-reflective roofing and other building materials having high reflectance of near-infrared radiation and high transmission of radiation in the visible light range and a substantial emissivity so as to reduce the heat island effects experienced by the articles while also maintaining an aesthetically pleasing appearance. Also disclosed are related methods for fabrication of such materials.
US08277939B2 Glass substrates coated or laminated with cured silicone resin compositions
An article of manufacture comprising (i) at least one glass substrate and (ii) a coating layer on at least a portion of at least one side of the glass substrate wherein the coating layer comprises a cured silicone resin composition selected from a hydrosilylation cured silicone resin composition, a condensation cured silicone resin composition, or a tree radical cured silicone resin composition; the glass being preferably a thin glass (5-500 micrometers).
US08277936B2 Hexagonal boron nitride compositions characterized by interstitial ferromagnetic layers, process for preparing, and composites thereof with organic polymers
The present invention relates to a hexagonal boron nitride platelet particle having a layer of a ferromagnetic metal between the layers of hexagonal boron nitride thereof, and a process for preparing the composition thereof. The present invention further relates to polymeric composites formed therefrom. The present invention describes improvements in thermal conductivity of said composites when subject to an orienting magnetic field.
US08277934B2 Coating system for cement composite articles
A coated article which includes a cement fiberboard substrate and a radiation-curable coating system applied to the substrate. The coating system includes an aqueous dispersion of water-dispersible polymer particles, one or more olefinic compounds and water, and may be provided in the form of one or more coating compositions that may be applied in one or more layers, wherein each of the coating compositions is preferably an aqueous composition, or can be mixed with another composition (e.g., on the substrate) to form an aqueous composition.
US08277932B2 Membranes, methods of making membranes, and methods of separating gases using membranes
Membranes, methods of making membranes, and methods of separating gases using membranes are provided. The membranes can include at least one hydrophilic polymer, at least one cross-linking agent, at least one base, and at least one amino compound. The methods of separating gases using membranes can include contacting a gas stream containing at least one of CO2, H2S, and HCl with one side of a nonporous and at least one of CO2, H2S, and HCl selectively permeable membrane such that at least one of CO2, H2S, and HCl is selectively transported through the membrane.
US08277931B1 Facer for insulation boards and other construction boards
The subject invention relates to a facer which is comprised of a breathable film and a glass mat, wherein the breathable film and the glass mat are bonded together with an adhesive, wherein the breathable film is comprised of a breathable polymeric material selected from the group consisting of polyolefins, nylons, polyesters, and thermoplastic elastomers, and wherein the facer is water resistant. The facers of this invention can be employed in manufacturing construction board, such as polyisocyanurate boards, polystyrene boards, or gypsum boards. The present invention accordingly more specifically discloses a construction board which is comprised of a rigid sheet and a facer, wherein the facer is bonded to at least one side of said rigid sheet, wherein the rigid sheet is comprised of a member selected from the group consisting of gypsum, blown polystyrene, and polyisocyanurate, wherein the facer is comprised of a breathable polymeric material selected from the group consisting of polyolefins, nylons, polyesters, and thermoplastic elastomers, wherein the breathable polymeric material is bonded to another substrate, such as a glass mat with an adhesive, and wherein the facer is water resistant.
US08277930B2 Moisture-permeable film, production method of same and laminate using same
An object of the present invention is to provide a moisture-permeable film having superior moisture permeability and flexibility at levels enabling the use thereof in the production of textile products such as clothes, while also not being susceptible to the occurrence of decreases in surface quality caused by roughening. The present invention relates to a moisture-permeable film obtained by curing a reactive polyurethane hot melt resin composition comprising a reactive urethane prepolymer (D), a (meth)acrylate (E) and a photopolymerization initiator (F), wherein the reactive urethane prepolymer (D) is obtained by reacting a hydroxyl group-containing (meth)acrylate (C) with 10% to 90% of the equivalent of isocyanate groups possessed by an urethane prepolymer obtained by reacting a polyisocyanate (B) with a polyol (A); and the polyol (A) contains a polyester polyol (a-1) which is obtained by reacting polycarboxylic acid with a polyol in which an alkylene oxide is added to bisphenol A, a poly ester polyol (a-2) which is a solid at normal temperature and a polyethylene glycol (a-3) which has a number average molecular weight of 1000 to 25,000.
US08277927B2 Electret and electrostatic induction conversion device
An electret in disclosed including a laminate. A layer (A) containing a resin (a) and a layer (B) containing a resin (b) other than the resin (a) or an inorganic substance (c) are directly laminated. The resin (a) is a fluororesin (a1), or a resin (a2) having an alicyclic structure and containing no fluorine atom. The layer (B) is disposed on the outermost surface on a side opposite to the side where electric charge is injected at the time of injecting electric charge into the laminate to form the electret.
US08277926B2 Methods for fabricating coatings for drug delivery devices having gradient of hydration
A method for fabricating a coating for an implantable medical device is provided comprising applying a first polymer on at least a portion of the device to form a first layer of the coating and applying a second polymer on at least a portion of the first layer to form a second layer of the coating. The second polymer has a lower degree of hydration than the first polymer.
US08277925B2 Multilayer mounting mat
A multilayer mounting mat operatively adapted for use in mounting a pollution control element in a pollution control device comprises a first layer, a second layer, and an adhesive sandwiched therebetween so as to bond together a major surface of the first layer to a major surface of the second layer, the adhesive comprising at least one of inorganic colloidal particles having an average diameter less than about 300 nm and an inorganic water-soluble salt.
US08277924B2 Panel-shaped molded product
The present invention relates to a panel-shaped molded product having a laminated structure which is produced from a resin and used for side doors, back doors, hoods, roofs, etc., and exhibits a more excellent finishing accuracy without occurrence of bleed-out along an inner periphery of a frame part and fine distortions on a design part. The panel-shaped molded product of the present invention is a molded product having a laminated structure which is obtained by injection-molding the frame part (2) on one surface of the plate-shaped design part (1) wherein an inner peripheral portion (4) of the frame part (2) is closely attached to the design part, and has a thickness changing region where a thickness of the frame part is reduced toward the side of a center of the frame part such that a ratio between a width of the thickness changing region and the thickness of the frame part (2), and a ratio between a width of the thickness changing region and a width of the frame part (2) are respectively adjusted to satisfy specific relationships.
US08277922B2 Stem web
A stem web is disclosed that comprises a backing layer having a first surface and a second surface, and an array of 600 to 20000 upstanding stems projecting from the first surface of the backing. The stems comprise a height from 0.3 and 2.0 millimeters and a shore hardness less than 90A. In one embodiment, the stem web further comprises a reinforcing layer secured to the second surface. In one embodiment, the stem web is secured to a tool to be passed across a surface to be cleaned to capture lint and hair.
US08277921B2 Honeycomb structure and method for manufacturing the same
A honeycomb structure includes a ceramic block including a plurality of honeycomb fired bodies, a first adhesive layer, and a second adhesive layer. The plurality of honeycomb fired bodies includes center-portion honeycomb fired bodies located at a center portion in a cross-section perpendicular to the longitudinal direction and peripheral honeycomb fired bodies surrounding the center-portion honeycomb fired bodies. The first adhesive layer is interposed between the center-portion honeycomb fired bodies to connect the center-portion honeycomb fired bodies. The second adhesive layer is interposed between each of the center-portion honeycomb fired bodies and each of the peripheral honeycomb fired bodies and between the peripheral honeycomb fired bodies. An adhesive strength α between the center-portion honeycomb fired bodies bonded via the first adhesive layer is higher than an adhesive strength β between honeycomb fired bodies bonded via the second adhesive layer.
US08277919B2 Reflective coating for an optical disc
An optical disc includes a substrate layer, a cover layer, and an aluminum alloy layer that is between the substrate layer and cover layer, and is adjacent to the substrate layer. The aluminum alloy layer includes a majority amount of aluminum and an additional metal selected from the group consisting of: chromium, titanium, tantalum, and any combination thereof. A method of making an optical disc includes the steps of: forming a substrate layer; sputtering an aluminum alloy target onto the substrate layer to form an aluminum alloy layer; and forming a cover layer; wherein the aluminum alloy layer comprises a majority amount of aluminum and an additional metal selected from the group consisting of: chromium, titanium, tantalum, and any combination thereof.
US08277916B2 Protective film systems and kits for vehicular windows and window assemblies and methods using the same
A protection system kit is provided for at least one vehicular window panel mounted in a window opening of a vehicle. The kit comprises a film unit supply assembly including a release liner and a multi-layer, self-adhesive film unit. The film unit includes a first film layer and a first adhesive layer releasably securing the first film layer to the release liner. The film unit further includes a second film layer secured to the first film layer on the release liner by a second adhesive layer. The second film layer is selectively removable from the first film layer by peeling the second film layer away from the first film layer. The first adhesive layer is adapted to secure the first film layer to a vehicular window panel in an associated window opening of a vehicle. The first and second film layers are pre-configured to fit the window opening.
US08277912B2 Organic polymer coatings for water containers
Water tanks, such as water heaters, are coated with an organic polymer coating, which coating contacts water during use of the water tank. The organic polymer coatings resist corrosion or blistering when used to store or contain water. The water tanks may be made by treating a metal surface prior to application of the organic polymer coating.
US08277910B2 Structure of fluid container and method and apparatus for producing the fluid container
A fluid container for packing a product includes a check valve for each container member. A bonding structure of check-valves to a fluid container and a production apparatus of fluid container are disclosed in detail where the check valve is capable of reliably keeping the expansion of the fluid container without any fluid leakage after inflating the fluid container. As the check-valve is bonded to only one of thermoplastic container films, both films of the check-valve are fixed to one of the container films at a plurality of seal portions, thereby preventing the reverse flow by tightly closing the check valve. The plurality of seal portions in a flow pass of the fluid disrupt the fluid flow so as to add resistance to the fluid flow.
US08277909B2 Transparent ink-jet recording films, compositions, and methods
Transparent ink-jet recording films, compositions, and methods are disclosed. These films can exhibit high maximum optical densities, rapid ink drying, low curl, excellent adhesion between the coating layers and the substrate, and negligible ink transfer between stacked ink-jet recording films after imaging. Such films are useful in medical imaging applications.
US08277905B2 Method for producing defect-free light guiding elements of great widths, production device and diffractive light guiding element
A process for producing a diffractive light guiding element by a continuous, single-stage reel-to-reel method, an apparatus suitable for carrying out the process and a light guiding element obtainable by the process.
US08277903B2 Synthesis and applications of soluble pentacene precursors and related compounds
The present disclosure relates to methods and systems for synthesis of bridged-hydropentacene, hydroanthracene and hydrotetracene from the precursor compounds pentacene derivatives, tetracene derivatives, and anthracene derivatives. The invention further relates to are methods and systems for forming thin films for use in electrically conductive assemblies, such as semiconductors or photovoltaic devices.
US08277902B2 Method for forming film and method for manufacturing light emitting device
A method for forming a film in which throughput is improved and a desired pattern is obtained smoothly in stacking a plurality of material layers over a substrate and a method for manufacturing a light emitting device are provided. In advance, a material layer is formed selectively by a droplet discharge method to be in contact with a light absorption layer on a first substrate. A second substrate is disposed so that the material layer faces the second substrate. The light absorption layer is irradiated with a laser light so that a film containing a material included in the material layer is formed on the second substrate. When the light absorption layer have a desired pattern, a film reflecting the pattern of the light absorption layer that has undergone the laser light irradiation is formed on the second substrate.
US08277897B2 Reactive polymer-supporting porous film for battery separator and use thereof
A reactive polymer-supporting porous film is provided as a battery separator which comprises a porous substrate film and a partially crosslinked reactive polymer supported on the porous substrate film. The partially crosslinked reactive polymer is obtained by the reaction of a crosslinkable polymer having at least one group selected from the 3-oxetanyl group and epoxy group reactive with a polycarboxylic acid. The reactive polymer-supporting porous film has a separator and electrodes sufficiently bonded to each other and with low inner resistance suitably used for production of battery excellent in high rate performance. Further, provided is a method of producing a battery which comprises placing the electrode/reactive polymer-supporting porous film layered body in a battery container; introducing an electrolytic solution containing a cationic polymerization catalyst into the battery container thereby bonding the porous film and electrodes together.
US08277896B2 Thin film dielectrics with perovskite structure and preparation thereof
Methods of making a ternary oxide and a perovskite-related ternary oxide structure are described. The methods include reacting a binary oxide with a metal oxide or a metal hydroxide to form a ternary oxide dielectric layer on a substrate. Powders, anodes, pressed articles, and capacitors including the ternary oxide or perovskite-related ternary oxide structure as a dielectric layer or other layers are further described.
US08277888B2 Dual path gas distribution device
An apparatus for deploying two fluids separately into a reaction chamber is provided. The apparatus includes a first distribution network that is formed on a plate having a distribution face and a dispensing face. The first distribution network is defined by a plurality of recessed channels on the distribution face. The plurality of recessed channels includes a plurality of thru-ports that extend from the plurality of recessed channels to the dispensing face. The apparatus further includes a second distribution network that has passages formed below the plurality of recessed channels and above the dispensing face. A first set of ports extends from the passages to the distribution face and a second set of ports extends from a top surface of the distribution face to the dispensing face.
US08277879B2 Method of manufacturing a platen roller for conveying a thermally active adhesive sheet
There are disclosed a platen roller capable of inhibiting drop of an adhesive force of a thermally active adhesive layer, which is seen in a case where recording and thermal activating are performed with respect to a thermally active adhesive sheet having the thermally active adhesive layer on a backside of a recording surface of a sheet-like substrate, a method of manufacturing the platen roller, and a recording device and a sticking label printer which are provided with the platen rollers. As the platen roller for conveying the thermally active adhesive sheet having the thermally active adhesive layer on the backside of the recording surface of the sheet-like substrate, a platen roller is used which is subjected to a contact treatment to bring the surface of a roller portion into contact with a compound (a) containable as a solid plasticizer in the thermally active adhesive layer.
US08277878B2 Hot-pressed transparent ceramics and ceramic lasers
A transparent polycrystalline ceramic having scattering and absorption loss less than 0.2/cm over a region comprising more than 95% of the originally densified shape and a process for fabricating the same by hot pressing. The ceramic can be any suitable ceramic such as yttria (Y2O3) or scandia (Sc2O3) and can have a doping level of from 0 to 20% and a grain size of greater than 30 μm, although the grains can also be smaller than 30 μm. Ceramic nanoparticles can be coated with a sintering aid to minimize direct contact of adjacent ceramic powder particles and then baked at high temperatures to remove impurities from the coated particles. The thus-coated particles can then be densified by hot pressing into the final ceramic product. The invention further provides a transparent polycrystalline ceramic solid-state laser material and a laser using the hot pressed polycrystalline ceramic.
US08277877B1 Method for applying protective laser facet coatings
A method for depositing protective coatings on front and rear facets of an optical device, such as a laser die, is disclosed. The protective coatings help prevent laser facet damage common to laser dies manufactured using known processes. In one embodiment, the method for coating the laser die includes placing the laser in an evacuated coating chamber before applying a first coating portion to a first facet of the laser. The first coating portion is applied to the first facet so as to form a protective covering thereon, but is applied at a coating energy that minimizes damage to the as-yet uncoated second facet. The laser is then rotated within the coating chamber, and a full coating is applied to a second facet of the laser. The laser is again rotated, and a full coating is applied atop the first coating portion to the first facet of the laser.
US08277876B1 UV camouflage system
A UV camouflage system for effectively camouflaging an individual or structure with respect to birds. The UV camouflage system generally includes identifying a landscape pattern for camouflage, identifying the color and UV reflection properties of the landscape pattern, and printing a UV camouflage pattern on an item that emulates the color and UV reflection properties of the landscape pattern.
US08277873B2 Method for manufacturing hydrogen separation membrane fuel cell
There is provided a method for manufacturing a fuel cell, such as a hydrogen separation membrane fuel cell, having in its anode a hydrogen separation membrane (12f) selectively permeable by hydrogen. An electrolyte membrane (10) is formed on the hydrogen separation membrane, and the curvature of the electrolyte membrane is changed to generate a compressive stress in the electrolyte membrane.
US08277867B2 Microdrop ablumenal coating system and method
Systems and methods for coating medical devices are provided that allow for relatively precise control over the deposition area and coating uniformity with improved efficiency. A microdrop source is used to provide a flow of coating microdrops. A charging electrode disposed near the outlet of the coating source gives each microdrop an electrostatic charge. As the microdrop travels toward the medical device to be coated, a control electrode alters the trajectory of the microdrop. The invention can include a scanner to scan or image the medical device as the coating is applied and a control system to adjust parameters of the deposition process based on information provided by the scanner.
US08277864B2 Liquid coffee concentrates and methods of making thereof
Methods for stabilizing liquid coffee concentrates are provided that form a coffee beverage that has a substantially consistent acidity profile. In one aspect, the methods blend a liquid coffee concentrate base with an edible alkali source in an amount effective to artificially increase a pH of the liquid coffee concentrate base. The liquid coffee concentrate base is aseptically processed and thermally treated at elevated temperatures for a time sufficient to artificially drive acid generating reactions in the liquid coffee concentrate to completion to form a stabilized liquid coffee concentrate.
US08277863B2 Method for simulating the functional attributes of human milk oligosaccharides in formula-fed infants
The present invention is directed to a novel method for increasing the production of acetate, decreasing the production of butyrate, increasing the population and species of beneficial bacteria and slowing the rate of fermentation of prebiotics within the gut of a formula-fed infant. The method comprises administration of a therapeutically effective amount of PDX to the infant.
US08277861B2 Beverage products having steviol glycosides and at least one acid
Beverage compositions including a steviol glycoside and an acid component are provided. The beverage has a titratable acidity of about 9 to about 11.
US08277860B2 Method of stabilizing 1,4-dihydroxy-2-naphthoic acid
A method for stabilizing 1,4-dihydroxy-2-naphthoic acid, which comprises reducing an oxygen dissolved in a solution containing 1,4-dihydroxy-2-naphthoic acid, and food or drink containing 1,4-dihydroxy-2-naphthoic acid.
US08277857B2 Method for producing fermented milk
The present invention provides a method for producing fermented milk, the method employing a lactic acid bacterium capable of improving proliferative properties of Bifidobacterium, and a fermented milk prepared by the production method. Specifically, the present invention provides a method for producing a fermented milk, including fermenting a fermentation base using both Lactococcus lactis strain having cell wall-enveloped proteinase, PrtP, and bacteria belonging to a genus Bifidobacterium, and a fermented milk prepared by the production method.
US08277853B2 Composition for hair and body application
The present invention relates to a novel composition and method using the same for topical application to mammalian subject's skin or hair particularly useful for promoting hair health and more particularly hair growth.
US08277850B2 Use of an active ingredient that is obtained from Cyperus esculentus for its anti-aging cutaneous action
A method of treating cutaneous aging using of at least one active ingredient obtained from Cyperus esculentus in a cosmetic and/or dermopharmaceutical composition that is designed to combat cutaneous aging, preferably by working on the specific markers of the dermis. Cosmetic and/or dermopharmaceutical compositions that include an active ingredient that is obtained from Cyperus esculentus, an active ingredient that is obtained from Cyperus esculentus, and its production process.
US08277848B2 Method for preparing aqueous solution of high-concentration calcium phosphate stable in neutral pH range
Disclosed herein is a method for preparing an aqueous solution of high-concentration calcium phosphate, the method comprising the steps of: preparing an acidic aqueous solution using an acidic chelating agent; and dissolving a calcium phosphate-based compound in the acidic aqueous solution, and then adding a pH-adjusting agent to the acidic aqueous solution to adjust the pH of the acidic aqueous solution. The disclosed aqueous solution does not form a precipitate after neutralization so that it can be used in various calcium-containing products, including foods, drugs, or quasi-drugs.
US08277841B2 Polyamide rate-modulated monolithic drug delivery system
This invention relates to a polyamide rate-modulated monolithic drug delivery system comprising at least one active compound and a biodegradable and biocompatible polyamide polymer. The polymer is selected for delivering, in use, the active compound, within a predetermined time frame depending on the biodegradable properties of the polymer, to a target organism or organisms. In one embodiment of the invention the polymer is modified by salting-out or crosslinking the polymeric material to achieve the desired biodegradability characteristics and, consequently, to control the release of the active compound.
US08277838B2 Transdermal delivery of drugs based on crystal size
A blend of at least two polymers in combination with a drug provides a pressure-sensitive adhesive composition for a transdermal drug delivery system in which the drug is delivered from the pressure-sensitive adhesive composition and through dermis when the pressure-sensitive adhesive composition is in contact with human skin. According to the invention, providing drug having differing crystal sizes as well as drug which is solublized in the pressure-sensitive adhesive composition controls the rate of drug delivery from the pressure-sensitive adhesive composition.
US08277835B2 Nutritional composition comprising immunoglobulins and oligosaccharides
The present invention provides a method and composition for the treatment and/or prevention of infection, said method comprising orally administering a composition to a mammal, said composition comprising a galactose containing indigestible oligosaccharide and immunoglobulin from the milk or colostrum of hyperimmunized cows.
US08277833B2 Medical devices having surface coatings
According to an aspect of the present invention, medical devices are provided which comprise a metallic region and a coating on all or part of the metallic region that comprises a multivalent acid.
US08277832B2 Microsphere-based materials with predefined 3D spatial and temporal control of biomaterials, porosity and/or bioactive signals
A tissue engineering scaffold for growing cells can include a plurality of biocompatible microspheres linked together to form a three-dimensional matrix. The matrix can include a plurality of pores for growing cells. The biocompatible microspheres can include first and second sets of microspheres. The first set of microspheres can have a first characteristic, and a first predetermined spatial distribution with respect to the three-dimensional matrix. The second set of microspheres can have a second characteristic that is different from the first characteristic, and a second predetermined spatial distribution that is different from the first predetermined spatial distribution with respect to the three-dimensional matrix. The first and second characteristics can selected a composition, polymer, particle size, particle size distribution, type of bioactive agent, type of bioactive agent combination, bioactive agent concentration, amount of bioactive agent, rate of bioactive agent release, mechanical strength, flexibility, rigidity, color, radiotranslucency, radiopaqueness, or the like.
US08277831B2 Drug-enhanced adhesion prevention
The present invention includes methods for the inhibition of post-operative adhesion formation between tissue surfaces in a body cavity having been subjected to a surgical procedure, which methods involve administering Pemirolast, or an analog thereof, directly to tissue surfaces in the body cavity in amounts and under conditions effective to inhibit formation of adhesions, and to delivery vehicles and compositions suitable for use for local, non-systemic administration of a drug to the body and directly to tissue within a body cavity having been subjected to a surgical procedure.
US08277828B2 Delivery system for bone growth promoting material
A delivery system that includes a bone growth promoting material encapsulated within a water absorptive gelatinizable covering is used to promote bone growth in order to repair a bone defect and/or strengthen a weakened bone region. The delivery system may be shaped and sized in order to fit within a bleeding wound (e.g. one that is formed in the gingiva when a tooth is extracted). The covering may be formed of a gelatinizable gauze that forms a gel-like material when moistened with water. The delivery system is contained within a moisture resistant package prior to use. Alternatively, the delivery system comprises a bone growth promoting material and thickening agent contained within a syringe that, upon adding water, form a viscous gel or stiff putty. A polymerizable resin may be placed over the bone growth composition after placement on a bone to form a protective barrier layer.
US08277823B2 Compositions and methods for stabilizing lipid based adjuvant formulations using glycolipids
The present invention relates to liposome formulations that are physically stable. In particular the present invention relates to steric stabilization of cationic liposomes by incorporating glycolipids into the liposomes. The stabilized liposomes can be used either as an adjuvant for antigenic components or as a drug delivery system. In particular the invention relates to vaccines with adjuvants in aqueous media for immunization, where the final product is stable.
US08277820B2 Process for preparing variant of Erysipelothrix rhusiopathiae surface protective antigen in E. coli
A variant of Erysipelothrix rhusiopathiae surface protective antigen SpaA protein or of a shortened form of SpaA (ΔSpaA) in which a portion of SpaA protein is deleted for protection from Erysipelothrix rhusiopathiae infection and a process for preparing the same are provided. Introduction of amino acid substitution at a specific site in the amino acid sequence of SpaA or ΔSpaA protein provides a variant of SpaA or ΔSpaA protein which is immunogenic and is expressed in E. coli as inclusion bodies. The variant of SpaA or ΔSpaA protein of the present invention may easily be recovered and purified since it is expressed in E. coli as inclusion bodies.
US08277819B2 Norovirus particle for use as an antiviral or vaccine
Norovirus capsid protein monomers having only the P domain, and not the hinge or S domain, can assemble spontaneously into an icosahedral form herein called the P-particle. Factors affecting the formation and stability of the P-particle, as well as providing methods for diagnosing and treating Norovirus-infected individuals and creating a vaccine for prevention of Norovirus infection are presented.
US08277814B2 Avian Astrovirus
The present invention relates to the fields of veterinary virology and immunology. In particular the invention relates to a novel avian Astrovirus; to antibodies or fragments thereof against the novel virus; to antigenic preparations, proteins, and DNA molecules of the novel avian Astrovirus; to vaccines of the novel virus or its antigenic preparations, protein, or DNA; to methods for the manufacture of such vaccines, and to diagnostic kits.
US08277813B2 Identification and molecular characterisation of proteins, expressed in the Ixodes ricinus salivary glands
The invention relates to a new polynucleotide which encodes a polypeptide expressed in the salivary glands of ticks, more particularly the Ixodes ricinus arthropod tick, during the slow-feeding phase of the blood meal have. The polynucleotide and related polypeptide may be used in different constructions and for different applications which are also included in the present invention.
US08277807B2 Pharmaceutical combinations
The invention provides combinations comprising (or consisting essentially of) one or more ancillary compound(s) and a compound of the formula (I): or salts, tautomers, solvates and N-oxides thereof; wherein R1 is hydroxy or hydrogen; R2 is hydroxy; methoxy or hydrogen; provided that at least one of R1 and R2 is hydroxy; R3 is selected from hydrogen; halogen; cyano; optionally substituted C1-5 hydrocarbyl and optionally substituted C1-5 hydrocarbyloxy; R4 is selected from hydrogen; a group —(O)n—R7 where n is 0 or 1 and R7 is an optionally substituted acyclic C1-5 hydrocarbyl group or a monocyclic carbocyclic or heterocyclic group having 3 to 7 ring members; halogen; cyano; hydroxy; amino; and optionally substituted mono- or di-C1-5 hydrocarbyl-amino; or R3 and R4 together form a monocyclic carbocyclic or heterocyclic ring of 5 to 7 ring members; and NR5R6 forms an optionally substituted bicyclic heterocyclic group having 8 to 12 ring members of which up to 5 ring members are heteroatoms selected from oxygen, nitrogen and sulphur. The combinations have activity as Hsp90 inhibitors.
US08277804B2 Antagonists of IL-6 to prevent or treat thrombosis
The present invention is directed to therapeutic methods using IL-6 antagonists such as antibodies and fragments thereof having binding specificity for IL-6 to prevent or treat thrombosis in diseases associated with abnormal blood coagulation or fibrinolysis. In preferred embodiments these patients will comprise those exhibiting elevated D-dimer or other coagulation cascade related proteins and optionally will further exhibit elevated C reactive protein prior to treatment. The subject therapies also may include the administration of other actives such as chemotherapeutics, anti-coagulants, statins, et al.
US08277802B2 Diagnosis and prevention of cancer cell invasion
The present invention relates to diagnostic and therapeutic methods in the field of malignant disorders. Most particularly, the invention provides methods of determining the invasivity of malignant disorders and methods for reducing the invasivity of malignant disorders including the prevention or treatment of cancer cell invasion.
US08277799B2 Inhibition of pathogens by probiotic bacteria
Compositions containing a lactic acid-producing bacterial strain, e.g., Bacillus coagulans for inhibition of pathogenic bacterial infections. Spores or extracellular products produced by the bacterial strains are also useful as inhibitory agents.
US08277798B2 Use of cells containing a specific DNA molecule as cytopathic agents to inhibit the proliferation of cells
The present invention relates to the use of cells containing in their genome a specific DNA molecule, as cytopathic agents able to inhibit the proliferation of cells, when these proliferative cells are contacted with the cells containing the above-mentioned DNA molecule.
US08277792B2 Peptides for active anti-cytokine immunization
Peptide of a size comprised between 5 and 40 amino acids, originating from a cytokine, in which at least one of its amino acids comprises at least one of its atoms separated by a distance d of less than 5 angströms from an atom of the receptor corresponding to said cytokine, the spacing d being evaluated on the basis of structural data, derivatives, immunogenic compounds comprising them, use of a peptide or peptide derivative or immunogenic compound for the preparation of a curative or preventative medicament intended for the treatment or prevention of diseases linked to an excess or to the presence of cytokines or for the treatment of an auto-immune disease and pharmaceutical compositions which contain at least one abovementioned peptide or peptide derivative or immunogenic compound as active ingredient.
US08277789B2 Method for inhibiting fading and enhancing color intensity of color-treated hair
The invention provides a method for inhibiting color fading in color-treated keratinous fibers, which method includes treating the keratinous fibers with a color-fade inhibiting-effective effective amount of a monoalkyl quaternary ammonium salt. The invention also provides a method for enhancing the intensity of color in color-treated keratinous fibers, which method includes treating the keratinous fibers with a color intensity enhancing effective amount of an alkyl a quaternary ammonium salt. Additionally provided are products for inhibiting the fading of color and increasing the intensity of color in color-treated keratinous fibers.
US08277787B1 Alkoxylated guerbet citrate polyesters
The present invention has as its objective a series of citrate polyesters that have based upon guerbet alcohols reacted with citric acid, and crosslinked by water soluble diols, resulting in polymers with improved water solubility. These polymers have a very low viscosity when one considers the molecular weight, and are ideally suited to personal care applications due to their unique feel delivered from aqueous solution or emulsions.
US08277785B2 Cosmetic compositions with encapsulated pigments and a method for using
There is a pigmented cosmetic composition. The composition has a cosmetically acceptable vehicle, a cosmetic active, and a plurality of encapsulated pigment particles. The particles have an encapsulant and an entrapped pigment within the encapsulant. The encapsulant has silicon dioxide and exhibits a refractive index of about 1.4 to about 1.6.
US08277781B2 Device for intranasal administration
Disclosed herein are devices and processes for preparing a vial for an intranasal administration of a medicament where the vial comprises reduced oxygen content.
US08277771B2 Continuous vapor grown carbon fiber, method for fabricating the same and applications thereof
A method for fabricating a continuous vapor grown carbon fiber, comprising: (a) providing a substrate which has a catalyst on its surface; (b) placing said substrate in a furnace; (c) loading said furnace with hydrogen, ammonia, or combinations thereof; (d) adjusting a temperature of said furnace to 400° C. to 900° C. to proceed heat treatment for 10 minutes to 2 hours; (e) adding a carbon-containing compound into said furnace; (f) adjusting the ratio of said carbon-containing compound and said hydrogen, ammonia, or combinations thereof; (g) adjusting the temperature of said furnace to 500° C. to 1200° C. to crack said carbon-containing compound, and thereby form a carbon fiber.
US08277769B2 Process for treating carbon dioxide containing gas
A process is disclosed for recycling carbon dioxide emissions from a fossil-fuel power plant into useful carbonated species The process primarily comprises the steps of: a) burning the fossil fuel, thereby generating heat and a hot exhaust gas containing CO2; and b) converting the heat into energy. The process is characterized in that it further comprises the steps of: c) cooling the exhaust gas; and d) biologically transforming the CO2 contained in the cooled exhaust gas into carbonated species, thereby obtaining a low CO2 exhaust gas and producing useful carbonated species. The low CO2 exhaust gas obtained in step d) can be released in the atmosphere without increasing the problem of greenhouse effect.
US08277768B2 System and method for production of high purity silicon solids and solids therefrom
Systems and methods and resulting compositions of matter including silicon solids from a mixture of silicon and water. The mixture is collected at a collection stage from at least one wafer abrasion process performed on a silicon surface having an impurity concentration ≦0.1 ppb and extracting one portion of the water from the mixture using at least one dryer stage to form a dry cake. The dry cake includes at least 99.99% silicon by weight excluding water and non-silicon species, where a concentration of water in the dry cake is between 0.05% and 1% by weight, and where a concentration of non-silicon species in the dry cake is between 0.05% and 1% by weight.
US08277767B2 Method and system for adsorbing pollutants and/or contaminants
The present invention relates to a method and a multi-component system for adsorbing contaminants and/or pollutants from a contaminated hot fluid by using a turbulent air stream, to adiabatically cool the temperature of the fluid, in association with one or more adsorbents. The system of the present invention can also be coupled to a recovery and recycling unit to recover and recycle the contaminant and/or pollutant and the adsorbent material.
US08277759B2 Microfluidic flow cell
A microfluidic flow cell having a body with a fluid transport channel disposed therein, the fluid transport channel having a proximal end and a distal end defining a fluid flow path, a fluid inlet port disposed at the proximal end of the fluid transport channel at a central portion of the body and an outlet port disposed at the distal end of the fluid transport channel at an outer portion of the body, and a plurality sample wells disposed in the fluid transport channel substantially perpendicular to the fluid flow path in the fluid transport channel. The microfluidic flow cell may have hundreds or thousands of individual, sub-microliter sample wells. The microfluidic flow cell can be filled by applying a flowable liquid to the inlet port and spinning the flow cell to cause fluid to flow into fluid transport channel. The microfluidic flow cells described herein can be used in a variety of applications where small sample size and/or a large number of replicates are desirable.
US08277758B2 Assembly for actuating a syringe
In an assembly for actuating a syringe, two gripping devices are designed to receive and withhold a containment cylinder and, respectively, a piston of the syringe, and are defined by respective pairs of jaws for gripping a flange of the containment cylinder and, respectively, of an end head of the piston, the jaws of at least one gripping device being mobile with respect to one another between a gripping position and a release position under the thrust of a corresponding actuation device.
US08277755B2 Apparatus for discharging packing material from sample column
The present invention provides an apparatus for discharging packing material from a sample column which is capable of removing the packing material such as activated carbon from the sample column for analysis having a tube shape smoothly and more certainly, and can be suitably used in the case where the packing material thus removed is supplied to an analyzer, etc. The apparatus for discharging packing material according to the present invention comprises a discharge apparatus body (4) which is disposed concentrically to the sample column (9) held in a predetermined position, and is capable of moving close to and away from the sample column; a column positioning hub (5) which is mounted to a tip end of the discharge apparatus body to be movable forward and rearward, and biased toward the sample column (9); a push-out pin which is inserted into the discharge apparatus body (4) and the column positioning hub (5) to extend substantially along center lines of the discharge apparatus body and the column positioning hub, and allowed to relatively project from the column positioning hub when the column positioning hub (5) is moved rearward; and a vibration generating means for applying vibration to the push-out pin (6) when the push-out pin is allowed project from the column positioning hub.
US08277750B2 Detector for chemical sensor device and use thereof
Disclosed is a detector for chemical sensor devices, the detector being improved in detection sensitivity. Also disclosed is use of such a detector for chemical sensor devices. Specifically, disclosed is a detector for chemical sensor devices by which a substance to be measured is detected by adsorbing the substance contained in a medium on the surface thereof. The detector includes an adsorption layer containing hydroxyapatite or a substituted apatite obtained by substituting a part of elements in hydroxyapatite on a surface which is used for detecting the substance to be measured. Such a detector is greatly improved in detection sensitivity, and thus able to detect a very small amount of a chemical substance.
US08277749B2 Time-temperature indicator based on valence isomerizations
The present invention relates to a time temperature indicator comprising at least one indicator compound in a first isomeric form, which is converted into a second isomeric form of said indicator compound in a valence isomerization reaction without migration of an atom or chemical group attached to said indicator compound in a time and temperature dependent manner, wherein the formation of the second isomeric form is detectable by monitoring a physical characteristic of the indicator. The present invention also relates to a method of manufacturing such a time-temperature indicator comprising the steps of (a) embedding in or atop a matrix said indicator compound; and (b) inducing the formation of a metastable state of said embedded indicator compound.
US08277745B2 Interchangeable load cell assemblies
A mass-based dispensing system includes a set of interchangeable load cell assemblies. The load cell assemblies are sized to be interchangeably received into a mass-based product dispenser. Each of the interchangeable load cell assemblies has a maximum rated load that is different from the maximum rated load of the other load cell assemblies. The interchangeable load cell assemblies are substantially modular (i.e., have substantially similar external geometries), thus enabling the product dispenser to interchangeably receive the load cells. The interchangeable load cell assemblies enable a single product dispenser to accommodate a broad range of differently weighted products and/or product containers.
US08277740B2 Ozone generator
An ozone generator includes a housing with a plurality of openings and containing an ultraviolet lamp and a blower. A control is remotely connected to the housing for turning the generator on and off. The ultraviolet lamp emits ultraviolet radiation. The blower moves air into contact with radiation from the ultraviolet lamp. A modular arrangement of the invention includes components for assembling an ozone generator. The arrangement includes a first generator component and a second generator component connected by a hose. Another embodiment of a modular arrangement includes a generator and a blower connected by a hose. A method for operating an ozone generator includes placing an ozone generator in an unoccupied, enclosed space; placing a controller that is connected to the generator outside of the enclosed space; and turning on the controller.
US08277737B2 Catalyst systems
The present invention provides monolithic structural catalysts. The catalysts have a thin wall structure and are advantageous for catalyzing reactions of gaseous fluid or liquid fluid molecules, such as the denitration or selective catalytic reduction (SCR) of nitrogen oxides (NOx) in combustion flue gases. In an embodiment, the honeycomb-like monolithic structural body includes catalytically active outer peripheral walls and a plurality of catalytically active thin-walled inner partition walls, the thin-walled inner partition walls adapted to enhance fluid flow through the monolithic catalytic body and to increase interaction of the fluid molecules with the catalyst body.
US08277733B2 Apparatus and method for making a peroxycarboxylic acid
The present invention relates to apparatus and methods for making a peroxycarboxylic acid. The apparatus includes a reaction catalyst and a guard column for pretreating one or more reagents, which can increase the life, activity, and/or safety of the reaction catalyst. The peroxycarboxylic acid compositions made by the method and apparatus can include one or more peroxycarboxylic acids.
US08277729B2 Sample analyzer, reagent aspirating method, and computer program product
The present invention is to present a sample analyzer which is capable of respond immediately when a need to perform analysis of multiple items arises. The sample analyzer 1 includes a table 12 capable of holding a first rack 320 and a second rack 330; a reagent dispensing arm 120 which comprises a pipette part 121; a reagent dispensing driving section 120a for moving the reagent dispensing arm 120; a reagent barcode reader 350; and a control section 501 for controlling the reagent dispensing driving section 120a so as to move the pipette part 121 to a predetermined reagent aspirating position according to the identification information obtained by the reagent barcode reader 350.
US08277727B2 Device and method for inactivation and/or sterilization using plasma
The invention concerns a method of sterilization and/or inactivation of at least one surface of at least one contaminated object. The method being characterized in that one subjects the surface to the discharge plasma generated from an applicator of electromagnetic field of linear type, the plasma having a temperature and an absorbed power per unit of volume predetermined by the operating conditions, so as to sterilize the surface without significantly degrading it. The invention also concerns a device enabling the sterilization and/or inactivation of at least one surface of at least one contaminated object by means of a plasma. This method and this device can be used to sterilize or inactivate several types of objects, such as packages, films, metal plates, dielectric plates, prosthesis used in the medical field, etc.
US08277724B2 Sterilization methods and systems
Methods and systems for sterilizing one or more areas or one or more portions of one or more areas are described. In some embodiments, the methods and systems can be used to sterilize one or more areas or one or more portions of one or more areas through use of sterilizing radiation. In some embodiments, the methods and systems can be utilized so that objects, such as humans, that are within one or more areas or one or more portions of one or more areas are not substantially irradiated with sterilizing radiation.
US08277718B2 Biodegradable film or sheet, process for producing the same, and composition for biodegradable film or sheet
The invention provides a biodegradable film or sheet having water resistance and strength sufficiently. Respective components are mixed so as to form a mixture containing 0% by mass or more and 35% by mass or less of starch, 20% by mass or more and 70% by mass or less of protein, 15% by mass or more and 60% by mass or less of cellulose fibers and 1% by mass or more and 15% by mass or less of urea, then adding 10 or more and 100 or less parts by mass of water to 100 parts by mass of the mixture, kneading the mixture sufficiently with a twin-screw mixer or the like, and rolling the kneaded product under heating at about 120° C. to give a film or sheet with several tens μm to about 300 μm in thickness.
US08277715B2 Process for manufacturing improved dispensing devices
The present invention relates to a method for the manufacture of a lavatory dispensing device useful for the delivery of at least one treatment composition, preferably a cleaning composition and/or a sanitizing composition to a sanitary appliance.
US08277713B2 Implantable analyte sensor
An implantable analyte sensor including a sensing region for measuring the analyte and a non-sensing region for immobilizing the sensor body in the host. The sensor is implanted in a precisely dimensioned pocket to stabilize the analyte sensor in vivo and enable measurement of the concentration of the analyte in the host before and after formation of a foreign body capsule around the sensor. The sensor further provides a transmitter for RF transmission through the sensor body, electronic circuitry, and a power source optimized for long-term use in the miniaturized sensor body.
US08277710B2 Biaxially oriented hydrolysis-stable polyester film comprising epoxidized fatty acid derivatives, and process for production thereof and use thereof
The invention relates to biaxially oriented polyester films which contain 0.1-5.0% by weight (based on the weight of the film) of a hydrolysis stabilizer based on epoxidized fatty acid esters and 0.2-10% by weight (based on the weight of the film) of epoxidized fatty acid glycerides, the epoxidized fatty acid esters having a mean molecular weight of at least 425 g/mol. Such films find use in outdoor applications, as a ribbon cable, as a backside laminate of solar modules and in electrical insulation applications.
US08277704B2 Method of manufacturing formed article, mold and method of manufacturing the same
The present invention relates to a method of manufacturing a formed article forming an upper surface of a forming material comprised of a thermosoftening substance into a desired shape by positioning the forming material on a forming surface of a mold and heating the forming material to a temperature permitting deformation to bring a lower surface of the forming material into tight contact with the forming surface. As the mold, a mold having, on a forming surface thereof, a plurality of irregularities with a maximum height Rmax ranging from 0.1 to 100 micrometers and an average spacing S between local peaks ranging from 0.01 to 1.00 mm is employed. The present invention further relates to a mold and method of manufacturing the same. According to the present invention, a formed article with a desired shape can be manufactured with high precision and high productivity by hot sag forming method without the occurrence of the fusion between the forming material and the mold.
US08277703B2 Smoke suppressants
The smoke suppressant comprises a molybdate precipitate on the surface of a borate core. The precipitate increases surface area of the core and provides improved smoke suppression relative to a mixture of the molybdate and borate core. The suppressants can be incorporated into polymer compositions to improve their smoke suppression capability.
US08277697B2 Color filter element with improved colorant dispersion
A color filter having a filter layer comprising a fluorinated phthalocyanine pigment and at least one second pigment. In one embodiment, the second pigment has a maximum absorption at a wavelength from 400 to 500 nm to create a green color filter.
US08277693B2 Method for producing fine particle dispersion and fine particle dispersion
A method for producing a fine particle dispersion includes the steps of reducing a metal ion to form a fine particle dispersion aqueous solution; adding an aggregation accelerator into the fine particle dispersion aqueous solution so that agglomerated or precipitated fine particles are separated to obtain fine particles; and re-dispersing the fine particles into an organic solvent containing an organic solvent having an amide group, a low boiling point organic solvent having a boiling point between 20° C. and 100° C. at a normal pressure, and an organic solvent having a boiling point higher than 100° C. at a normal pressure and containing an alcohol and/or a polyhydric alcohol.
US08277692B2 Semiconductive rubber composition and semiconductive rubber roller employing the same
The semiconductive rubber composition according to the present invention contains: a rubber content containing at least copolymer rubber containing ethylene oxide as a copolymeric component and chloroprene rubber; and not less than 0.5 parts by mass and not more than 1.5 parts by mass of a thiourea-based vulcanization accelerator, not less than 0.5 parts by mass and not more than 1.5 parts by mass of a guanidine-based vulcanization accelerator and not less than 0.5 parts by mass and not more than 2.0 parts by mass of a peroxide-based crosslinking agent with respect to 100 parts by mass of the sum of the rubber content.
US08277689B2 Stabilizer composition for improved protection against degradation of organic substrates by light
The invention relates to combinations of benzylidene-bis-malonate based lightsstabilizers with specific other additives showing synergistic efficiency during long term light exposure of organic substrates.
US08277686B2 Sialon phosphor particles and production method thereof
To provide sialon phosphor particles or a powder exhibiting high emission intensity in the region from ultraviolet to blue and not requiring a strong pulverization operation for pulverizing a sintered body or a large aggregated lump, and a production method thereof. Sialon phosphor particles represented by the formula: MxLnySi12−(m+n)Al(m+n)OnN16−n (wherein M is at least one metal selected from the group consisting of Li, Ca, Mg and Y, Ln is a lanthanide metal containing at least Eu, and assuming that the valence of the metal M is a and the valence of the lanthanide metal Ln is b, ax+by=m, x is 0
US08277685B2 Dispersant having multifunctional head and phosphor paste composition comprising the same
Disclosed is a dispersant having a multifunctional head, and a phosphor paste composition comprising the dispersant. The dispersant has a multifunctional head that comprises an acidic group, a basic group and an aromatic group, thereby enhancing an affinity for the surface of phosphor particles and improving dispersibility.
US08277680B2 Method of manufacturing piezoelectric/electrostrictive ceramic composition
A (Li, Na, K)(Nb, Ta)O3-based piezoelectric/electrostrictive ceramic composition having large electric field-induced distortion at the time of application of a high electric field is provided. A perovskite oxide is synthesized which contains Li (lithium), Na (sodium) and K (potassium) as A-site elements and contains at least Nb (niobium) and Sb (antimony) out of Nb, Ta (tantalum) and Sb as B-site elements, the ratio of the total number of atoms of the A-site elements to the total number of atoms of the B-site elements being larger than 1, and then a Bi (bismuth) compound is added and reacted. The amount of addition of the Bi compound with respect to 100 molar parts of the perovskite oxide is preferably not less than 0.02 molar part nor more than 0.1 molar part in terms of Bi atoms.
US08277679B2 Composite magnetic material and magnetic element
The object of the present invention is to provide a composite magnetic material having well-balanced magnetic properties and chemical properties, and a magnetic element using thereof. Concretely, the present provides the composite magnetic material comprising a binder and a magnetic powder contains followings: Mn not less than 0.25 wt % and not larger than 3 wt %, Si not less than 1 wt % and not larger than 7 wt %, Cr not less than 2 wt % and not larger than 8 wt %, and the rest of Fe and inevitable impurities with respect to the total weight of a magnetic powder material, and a ratio of powder particles having the major/minor axis is not less than 2 is not larger than 5% of the total powder particles.
US08277675B2 Method of damaged low-k dielectric film layer removal
An apparatus, system and method for removing a damaged material from a low-k dielectric film layer include identifying a control chemistry, the control chemistry configured to selectively remove the damaged material from the low-k dielectric film layer, the damaged material being in a region where a feature was formed through the low-k dielectric film layer; establishing a plurality of process parameters characterizing aspects of the damaged material to be removed and applying the control chemistry to the low-k dielectric film layer, the application of the control chemistry being defined based on the established process parameters of the damaged material, such that the damaged material is substantially removed from the areas around the feature and the areas around the feature are substantially defined by low-k characteristics of the low-k dielectric film layer.
US08277672B2 Enhanced focused ion beam etching of dielectrics and silicon
Silicon, silicon dielectrics and low-k dielectrics are etched in a focused ion beam process using gaseous fluorinating etchants selected from the group of triethylamine trihydrofluoride (TEATHF) and xenon fluoride. Xenon fluoride is combined with a secondary protecting agent to avoid undesired corrosion of bare silicon. The protecting agent may be an oxidizing agent such as oxygen, perfluorotripentylamine (PFTPA), or a heavy completely fluorinated hydrocarbon.
US08277668B2 Methods of preparing printed circuit boards and packaging substrates of integrated circuit
A method of forming printed circuit boards and packaging substrates. After blind vias are created in a dielectric layer, a first seed layer is provided in the vias and on the dielectric layer. Copper is applied to fill the vias and to form a copper layer over the vias and over the first seed layer. The first seed layer and the copper layer are removed and a second seed layer is formed on the dielectric layer and the exposed surfaces of the vias. A wire pattern is then formed using a photo-sensitive thin film applied to the second seed layer, and the wires in the wire pattern are thickened. The photo-sensitive thin film and the exposed portions of the second seed layer are removed to form a first conductive pattern of wires. The process may be repeated to form a second conductive pattern of wires on the first pattern.
US08277667B2 Magnetic element and manufacturing method therefor
A magnetic element and its manufacturing method are provided. A magnetic element includes an actuation part having a first surface and a second surface, a torsion bar connected to the actuation part, and a frame connected to the first torsion bar, wherein the first surface of the actuation part is an uneven surface. The manufacturing method of the magnetic element starts with forming an passivation layer on a substrate and defining a special area by the mask method, then continues with forming the adhesion layer and electroplate-initializing layer on the substrate sequentially. The photoresist layer are formed and the magnetic-inductive material is electroformed on the electroplate area. Finally, the substrate is etched and the passivation layer is removed to obtain the magnetic element. The manufacturing method of magnetic element of the present invention can be applied in the microelectromechanical system field and other categories.
US08277665B2 Method of washing a particulate filter bed using an underdrain
An apparatus for filtering water and/or wastewater including at least one underdrain lateral having a primary gas chamber and a secondary gas chamber where the secondary gas chamber serves to equalize pressure differences that may occur during the initial distribution due to velocity head changes and friction effects. Preferably, the underdrain lateral includes a plurality of chambers directing a washing fluid into the filter bed where at least one of the plurality of chambers directs a liquid and a gas simultaneously into the filter bed and at least one other chamber of the plurality of chamber directs only one of a liquid and a gas into the filter bed at the same time as that the combination of liquid and gas is directed into the filter bed.
US08277664B2 Extraction of anions from solutions and mixtures using hyperbranched macromolecules
Hyperbranched macromolecules and methods are described for selectively filtering contaminants such as anions from water and non-aqueous solutions, particularly in the presence of competing contaminants including other anions. The hyperbranched macromolecules may contain alkyl, 2-hydroxyalkyl, 2-methyl-2-hydroxylalkyl, 2-hydroxy-2-phenylalkyl, and other groups, which may be hydrophilic or hydrophobic. The molecules may preferentially bind to the contaminant at interest at low pH, and release the contaminant at a pH of about 9. The molecules may be used to filter contaminants including perchlorate and nitrate even in the presence of high sulfate concentrations.
US08277663B2 Blended salt composition and method of using
Novel water softening compositions and methods of treating hard water are provided. The compositions comprise a blend of sodium chloride and potassium chloride. The compositions are useful for regenerating ion exchange material in a water softening system and providing softened water containing both sodium and potassium ions.
US08277661B2 Microporous molecular separation membrane with high hydrothermal stability
A hydrothermally stable, microporous organic-inorganic hybrid membrane based on silica, having an mean pore diameter of between 0.2 and 1.5 nm, is characterised in that between 5 and 40 mole % of the Si—O—Si bonds have been replaced by moieties having the one of the formulas: Si—{[CmH(n-1)X]—Si—}q, Si—[CmH(n-2)X2]—Si or Si—CmHn—Si{(CmHn)—Si—}y in which m=1-8, n=2m, 2m−2, 2m−4, 2m−6 or 2m−8; provided that n≧2, X=H or (CH2)pSi, p=0 or 1, and q=1, 2, 3 or 4. The membrane can be produced by acid-catalysed hydrolysis of suitable bis-silane precursors such as bis(trialkoxysily)alkanes, preferably in the presence of monoorganyl-silane precursors such as trialkoxy-alkylsilanes.
US08277660B2 Method and apparatus for recovery of water containing silica
Disclosed are embodiments of a method and apparatus for the treatment of water containing silica in order to recover as much treated water from a water source as possible while minimizing the generation of waste products. Other embodiments include removing specific elements from the water source and utilizing those elements. Embodiments of the method and apparatus uses in-line physical and physio-chemical treatment methods to remove potential biological, colloidal and hardness foulants continually so that there is minimal loss of water from the water source stream and minimal addition of chemicals to accomplish removal or reduction of these potential recovery-limiting foulants.
US08277659B2 Microchip capillary electrophoresis absent electrokinetic injection
Microchip capillary electrophoresis (CE) utilizing a sample injector based on a mechanical valve rather than electrokinetic injection can provide improved sample injections, enhanced capabilities, and can eliminate the need for changing the electric field in the separation channel to induce sample injection. In one instance CE electrodes continuously apply an electric field for CE separation along a separation channel. A sample channel is connected to the separation channel at an intersection and has a sample pressure that is greater than that which is present in the separation channel near the intersection. The sample channel does not have electrodes that apply voltages for electrokinetic injection. A sample injector in the sample channel or at the intersection comprises a mechanical valve to control sample injection from the sample channel to the separation channel.
US08277652B2 Oil-sludge filtration system with aeration pump
A system for consolidating and removing contaminate such as paint sludge or oils from a fluid mixture. A contaminate tank receives a supply of the fluid mixture containing contaminate from a source such as a manufacturing line where overspray of paints or cleaning solutions containing washed away oils are collected. A free floating weir floats on the surface of the contaminate tank and mechanically separates and removes contaminate from a surface of the contaminate tank and concentrates the contaminate in a consolidation tank. In the consolidation tanks the contaminate is further separated and collected for disposal.
US08277650B2 Methods and apparatus for centrifugal liquid chromatography
Apparatus and methods related to centrifugal liquid chromatography are described. An angular velocity can be simultaneously imparted to a large number of chromatographic enclosures. Via centrifugal forces, a mobile phase fluid including a sample can be driven through a stationary phase within the chromatographic enclosure to perform a chromatographic separation process on components of the sample. The use of centrifugation as a driving force can allow significantly smaller stationary phase particles to be employed as compared to high performance liquid chromatography (HPLC). Further, for an equivalent chromatographic separation process, the use of centrifugation can provide much greater separation efficiencies than HPLC.
US08277649B2 Membranes and associated methods for purification of antibodies
The invention relates to a device for separating unwanted compounds from an antibody containing biological sample. The device comprises a porous support and a polymeric resin disposed within the pores of the porous support. The device may further comprise a viral clearance membrane upstream or downstream from the polymeric resin. Methods of use are also provided.
US08277645B2 Automatic retractable screen system for storm drain inlets
A screen system having first and second side members, each having a locking gear reversibly movable from a locked position to an unlocked position. A screen is coupled to the side members. The screen has openings and is rotatable from a closed position to an open position. The screen is engagable with the locking gears to preventing the screen from rotating from the closed position to the open position. A trigger plate is movably coupled to the screen, rotates from a first position to a second position and is engagable with the locking gears to prevent the locking gears from moving from the locked position to the unlocked position. The trigger plate disengages with the locking gears when water flows against it, allowing the locking gears to move from the locked position to the unlocked position and the screen to rotate from the closed position to the open position.
US08277644B2 Filtering device
Provided is a filtering device including a filter part having a plurality of filters stacked to filter contaminants in fluid, and a sample part disposed on an outer plane of the filter part and having a plurality of samples corresponding to the filters, respectively. Therefore, a filter exchange period can be accurately determined by measuring properties of the filter varied during filtering of contaminants, and indiscriminate exchange of the filters can be prevented to reduce maintenance cost.
US08277642B2 System for separating bitumen from oil sands
Disclosed is a system for processing oil sands to remove bitumen, the viscous petroleum product adhered to the sands, from the sands itself. The processing system is designed to be substantially air tight, preventing outside air from entering and volatile chemicals from escaping from the system. Mined oil sands are delivered to the system, which creates a slurry of oil sands and solvent in a slurry chamber. The slurry is transported to a dissolution chamber which conditions the slurry before the slurry is sent to an extraction chamber. A plurality of trays and scrapers further conditions the slurry to remove bitumen. The use of heavy, aromatic solvents and light, paraffinic solvents in sequence improves bitumen recovery while allowing environmentally safe processing of the sands to occur in a later step. The sands are dried and the solvent recovered for recycling and reuse in the system. Clean, dry sands are returned to the source of mined oil sands for reclamation.
US08277641B2 Separation vessel or part thereof, and process relating thereto
One exemplary embodiment can be a stack for a separation vessel adapted to receive a fluid having one or more phases. The stack may include one or more walls surrounding a void, a packed bed positioned within the void, and a distributor positioned above the packed bed. Generally, the stack has a height greater than its width. Usually, the separation vessel further includes a base having a length greater than its height, and the height of the stack is orientated substantially perpendicular to the length of the base.
US08277639B2 Steam cracking of high TAN crudes
The invention is directed to a process comprising feeding high TAN feedstreams to a steam cracker, whereby naphthenic acids in the feedstreams are substantially converted to CO, CO2, and low amounts of smaller acids (e.g., formic, acetic, propionic, and butyric acids). The feedstream is preferably a high TAN feedstream comprising crude or high TAN feedstream which has previously been subjected to a refinery process to remove resid.
US08277637B2 System for upgrading of heavy hydrocarbons
Systems and methods for processing one or more hydrocarbons are provided. One or more hydrocarbons can be selectively separated to provide one or more heavy deasphalted oils. At least a portion of the heavy deasphalted oil can be cracked using a fluidized catalytic cracker to provide one or more lighter hydrocarbon products.
US08277636B2 Glucose sensor and glucose level measuring apparatus
The present invention relates to a glucose sensor (2) including an electrode (32) which includes a conductive component and glucose dehydrogenase immobilized to the conductive component. As the glucose dehydrogenase, use is made of a protein complex including a catalytic activity subunit which has glucose dehydrogenase activity, and an electron mediator subunit for supplying an electron donated from the catalytic activity subunit to the conductive component. Preferably, the glucose sensor (2) is designed to continuously measure the glucose level or successively measure the glucose level a plurality of times.
US08277633B2 Process for producing scorodite and recycling the post-scorodite-synthesis solution
The present invention is to provide a process for producing a scorodite that can shorten the time required for synthesizing the scorodite, and further can improve the yield of arsenic and iron into the scorodite. Accordingly, a process for producing a crystalline scorodite from an acidic aqueous solution containing pentavalent As and trivalent Fe, wherein the synthesis of the crystalline scorodite is performed after the molar ratio of trivalent Fe to pentavalent As contained in the acidic aqueous solution is adjusted to be equal to or more than 0.9 and equal to or less than 1.1 is provided.
US08277626B2 Method for depositing an electrodepositable coating composition onto a substrate using a plurality of liquid streams
The present invention is directed to a method for coating a substrate wherein the substrate is electrically conductive, the method comprising simultaneously applying a plurality of electrically conductive liquid materials to different portions of the substrate wherein at least one of the electrically conductive liquid materials comprises an ionic compound; and applying an electrical current to at least one of the liquid materials thereby depositing the ionic compound onto the substrate.
US08277624B2 Method and apparatus for fluid processing a workpiece
A workpiece holder for fluid processing a workpiece including a transportable frame, a flexible member connected to the frame and defining at least one retaining feature, and a ring comprising at least one engagement feature engageable with the at least one retaining feature of the flexible member, wherein the flexible member is flexed to provide a force to the at least one engagement feature to cause the ring to form a barrier to fluid entry with the workpiece.
US08277617B2 Conformal magnetron sputter deposition
An apparatus and method for magnetron sputter coating of an interior surface of a hollow substrate defining at least one irregular contour. The apparatus may contain a vacuum chamber and a target containing one or more metals having an exterior surface defining at least one irregular contour. The exterior surface of the target may be configured to conform to at least a portion of an irregular contour of the interior surface of the hollow substrate to be coated. A magnet assembly may be supplied which may include a plurality of magnets where the magnets are positioned substantially within a metallic target alloy.
US08277615B2 Method for the distillative purification of slow-evaporating fluids
The present invention relates to a method for removing volatile compounds from sparingly volatile fluids by means of rectification using an auxiliary and also to separation methods and chemical reactions in which sparingly volatile fluids are used, the purification of which is effected by means of rectification and using an auxiliary.
US08277610B2 Mechanical fiber paper with controlled curl
A xerographic paper and method of forming includes mechanical fiber and a predetermined curl control defined by a split sheet contraction measurement. The split sheet contraction can be between about 0.8 and about 1.2 and between about 0.9 and about 1.1. Split sheet contraction is defined by a relationship of paper shrinkage in a cross-direction to paper shrinkage in a machine-direction and between the two sides of the sheet when split in the Z-direction.
US08277609B2 Tissue machine parent roll having variable intrinsic sheet dryness
The intrinsic tissue sheet properties of tissue sheets wound into a parent roll during manufacturing can be purposely varied in order to provide a z-directional gradient within the parent roll. For example, the moisture content of the tissue sheet can be made lower in the core region of the parent roll and greater in the outer region of the parent roll. Such gradients can ultimately provide more uniformity of the intrinsic property within the final tissue product.
US08277607B2 Cellulosic and lignocellulosic structural materials and methods and systems for manufacturing such materials
Methods of treating wood and wood products include irradiating untreated wood having a first molecular weight with ionizing radiation to cause an increase in the molecular weight of a cellulosic component of the wood to a second, relatively higher molecular weight.
US08277606B2 Method of providing paper-making fibers with durable curl and absorbent products incorporating same
A process for producing high bulk cellulosic fiber exhibiting a durable elevated curl index includes: (a) concurrently heat treating and convolving cellulosic fiber pulp at elevated temperature and pressure at high consistency under conditions selected so as to preclude substantial fibrillation and attendant paper strength and fiber bonding development; and (b) recovering the pulp wherein the length weighted curl index of the treated fiber is at least about 20% higher than the length weighted curl index of the fiber prior to the heat treatment and convolving thereof. The curl imparted to the fiber persists upon treatment for 30 minutes in a laboratory disintegrator at 3000 rpm at 1% consistency at a temperature of 125° F. Moreover, the curl may be imparted to the fiber in a disk refiner at very short residence times, on the order of several seconds or less. In general, the process is carried out in the presence of saturated steam at a pressure of from about 5 to about 150 psig.
US08277605B2 Thermosetting solution composition and prepreg
A thermosetting solution composition composed of a biphenyltetracarboxylic acid compound containing a partial lower aliphatic alkyl ester of 2,3,3′,4′-biphenyltetracarboxylic acid and/or a partial lower aliphatic alkyl ester of 2,2′,3,3′-biphenyltetracarboxylic acid, an aromatic diamine compound in a molar amount larger than a molar amount of the biphenyltetracarboxylic acid compound, a partial lower aliphatic alkyl ester of 4-(2-phenylethynyl)phthalic acid compound in a molar amount as much as 1.8-2.2 times a molar amount corresponding to a difference between the molar amount of the aromatic diamine compound and the molar amount of the biphenyltetracarboxylic acid compound, and an organic solvent composed of a lower aliphatic alcohol is of value for manufacture of a prepreg.
US08277591B2 Tubular slat for coverings for architectural openings
A slat or vane for use in a covering for an architectural opening is suitable for use in either a horizontal or vertical orientation and in a horizontal orientation will not sag or droop, and in a vertical orientation will rotate uniformly along its length when rotated from end thereof. The slat is formed in a tubular configuration and has a base material of glass fibers bonded together in a thermoformable resin so as to maintain the arcuate curvature desired for the tubular slat or vane. The slat can be repeatedly deformed and will always return to its original configuration.
US08277588B2 Method of adhering an object to the exterior of a motor vehicle
Dissolving paper (22) covers pressure sensitive adhesive (20) on a mounting face (18) of an object (16) to be mounted on an exterior surface of a body panel (10) of a motor vehicle by a mechanical fastening system (24). The mounting is exposed to a water wash. Water begins to be absorbed by the dissolving paper through the edge of the paper's outer perimeter. As the paper increasingly absorbs water, it dissolves in the water exposing the adhesive which then adheres to the panel.
US08277587B2 Continuous method and system for manufacturing liquid-crystal display elements
A continuous manufacturing method and system for liquid-crystal display elements which enhances accuracy, increases speed and improves in yield in the continuous production of liquid crystal elements. The continuous method and system performs steps of, defining a plurality of defective and normal-polarizing-sheet slitting positions on a continuous web of optical film, based on positions of defects existing in the optical film, and applying only normal polarizing sheets to a liquid-crystal panel. The polarizing sheet includes the defective and normal-polarizing-sheet slitting positions recorded as encoded information which is used to determine whether the polarizing sheet defined between slit lines sequentially formed in the continuous web, is a normal polarizing sheet, peeling the normal polarizing sheet from the carrier film and applying the normal polarizing sheet to the liquid-crystal panel.
US08277584B2 Extremely insensitive detonating substance and method for its manufacture
The present invention provides an explosive composition of substantially reduced sensitivity and low flammability, being definable as an extremely insensitive detonating substance (EIDS) according to UN Regulations for the Transport of Dangerous Goods and comprising one or more explosive material 42-58% vol., one or more fire retardant material 15-26% vol. and a binder 20-36% vol.
US08277582B2 Hydrogen absorbing alloy, hydrogen absorbing alloy electrode, secondary battery, and production method of hydrogen absorbing alloy
The present invention provides a hydrogen absorbing alloy containing a phase of a Pr5Co19 type crystal structure having a composition defined by a general formula A(4−w)B(1+w)C19 (A denotes one or more element(s) selected from rare earth elements including Y (yttrium); B denotes an Mg element; C denotes one or more element(s) selected from a group consisting of Ni, Co, Mn, and Al; and w denotes a numeral in a range from −0.1 to 0.8) and having a composition as a whole defined by a general formula R1xR2yR3z (15.8≦x≦17.8, 3.4≦y≦5.0, 78.8≦z≦79.6, and x+y+z=100; R1 denotes one or more element(s) selected from rare earth elements including Y (yttrium); R2 denotes an Mg element, R3 denotes one or more element(s) selected from a group consisting of Ni, Co, Mn, and Al; the numeral of Mn+Al in the z is 0.5 or higher; and the numeral of Al in the z is 4.1 or lower).
US08277580B2 Al-Zn-Cu-Mg aluminum base alloys and methods of manufacture and use
A rolled or forged Al—Zn—Cu—Mg aluminum-based alloy wrought product having a thickness from 2 to 10 inches. The product has been treated by solution heat-treatment, quenching and aging, and the product comprises (in weight-%): Zn 6.2-7.2, Mg 1.5-2.4, Cu 1.7-2.1. Fe 0-0.13, Si 0-0.10, Ti 0-0.06, Zr 0.06-0.13, Cr 0-0.04, Mn 0-0.04, Mn 0-0.04, impurities and other incidental elements ≦0.05 each. Alloys per se and aircraft and aerospace uses, as well as methods of making products are also disclosed.
US08277578B2 Rare earth permanent magnet and its preparation
A rare earth permanent magnet is prepared by disposing a powdered metal alloy containing at least 70 vol % of an intermetallic compound phase on a sintered body of R—Fe—B system, and heating the sintered body having the powder disposed on its surface below the sintering temperature of the sintered body in vacuum or in an inert gas for diffusion treatment. The advantages include efficient productivity, excellent magnetic performance, a minimal or zero amount of Tb or Dy used, an increased coercive force, and a minimized decline of remanence.
US08277576B2 Steel material composition for producing piston rings and cylinder lines
A steel material composition, in particular for producing piston rings and cylinder sleeves, contains the following elements in the cited fractions relative to 100% by weight of the steel material: 0.5-1.2% by weight C, 0-3.0% by weight Cr, 72.0-94.5% by weight Fe, 3.0-15.0% by weight Mn and 2.0-10.0% by weight Si. It can be produced by melting the starting materials and casting the melt into a pre-fabricated mold.
US08277573B2 Process for the production of a grain oriented magnetic strip
A process for the production of a grain oriented magnetic strip, made of steel containing 2.3 to 5.0% of silicon, obtained by producing a hot-rolled sheet containing a distribution of second phases capable of controlling the secondary recrystallization by means of a two-step hot-rolling with an intermediate annealing, and by changing it into the final product.
US08277572B2 Drive unit in particular for use in connection with tank cleaning equipment
To ensure that liquid and/or vapors do not escape from a tank space during cleaning by means of cleaning equipment, a housing (2) is provided with magnetic coupling equipment according to the invention, comprising two cooperating pole elements (8,9) which extend hermetically isolated from each other with pole parts extending in the turbine housing (3) on the tank space side and the gear housing (1) itself outside the tank space, respectively. This provides a considerable degree of security against liquid and gas leakage, while making it possible to achieve a compact structure with easy access for service and maintenance.
US08277571B2 Methods and apparatus for detecting pump cavitation in a dishwasher using frequency analysis
Water fill level detection techniques are provided for a dishwasher system. A dishwasher system includes a tub; a fluid circulation system for circulating water in the tub and a controller. The fluid circulation system includes at least one motor and at least one fill valve. The controller monitors a current drawn by the motor to control an operation of the fill valve. The controller performs a frequency analysis on the current to detect a water fill level in the tub.
US08277569B2 Substrate treating apparatus and substrate treating method
A substrate processing apparatus and a substrate processing method are capable of restraining or preventing the generation of streaky particles on a substrate surface by excellent removal of a rinsing liquid therefrom. The substrate processing apparatus has a substrate inclining mechanism for inclining a substrate held by a substrate holding mechanism. After a rinsing liquid has been supplied onto a substrate to form a liquid mass, the substrate is inclined at a small angle by the substrate inclining mechanism. Then, the liquid mass is downwardly moved without being fragmented and then falls down without leaving minute droplets on the substrate top. Thereafter, the substrate is returned to a horizontal posture and then dried.
US08277568B2 Rinse aid
A method of washing ware in an automatic ware washing machine, is disclosed, using a rinse aid composition containing a polysaccharide. The polysaccharide adsorbs on the ware resulting in a sheeting action of the rinse solution leading to improved drying of the ware.
US08277562B2 Continuous vacuum pan and internal insulation arrangement thereof
This invention relates to a continuous vacuum pan (also sometimes referred to as an evaporative crystallizer) for use in the sugar processing industry, and to a heat exchanger used inside the continuous vacuum pan. The invention also relaters to the heat exchanger as used in other applications in the sugar processing industry. The heat exchanger includes a massecuite flow path for conveying massecuite therethrough, and a heat transfer medium flow path for receiving a heat transfer medium to enable heat transfer to the massecuite flow path. The heat exchanger is characterized therein that a periphery thereof is surrounded by an insulated zone in order to prevent heat transfer from the heat transfer medium flow path to the environment.
US08277560B2 CVD apparatus and method of cleaning the CVD apparatus
A CVD apparatus cleaning method that efficiently removes by-product such as SiO2 or Si3N4 adhered to and deposited on surfaces of an inner wall, an electrode, and the like in a reaction chamber at a film forming step. In the cleaning method the discharged cleaning gas amount is very small, environmental influences such as global warming can be lessened, and cost can be reduced. A CVD apparatus supplying reactive gas into a reaction chamber and forming a deposited film on a surface of a base material provided in the reaction chamber includes an exhaust gas recycling path recycling an exhaust gas reaching the reaction chamber from downstream of a pump on an exhaust path for exhausting a gas from an inner part of the reaction chamber through the pump.
US08277557B2 Agglomerated particulate lignosulfonate
An agglomerated particulate lignosulfonate material may be made by introducing or forming lignosulfonate microparticles in a fluidized bed agglomerator, and introducing sufficient heated gas and lignosulfonate liquid in the agglomerator to convert the microparticles to lignosulfonate granules of enlarged size. The granules may have an average size of at least 0.1 mm, and may be used to make a dry-blended cement additive or oil well cement that may be dustless, easily poured and stored, and rapidly dissolved in water.
US08277556B2 Articles made from cementitious foam and slurry
Lightweight cementitious foams of the invention have excellent dynamic and dimensional stability due to use of foaming system comprising polycarboxylate surfactant foam generating agent, foam stabilizer (e.g., PVOH), and shrinkage reducing admixture to inhibit plastic shrinkage and micro-cracking of cement. The foaming system can be used in conventional cement mortars or concretes as well as with exemplary cementitious slurry systems of the invention, which include an expansive agent, a cross-linking agent for the foam stabilizer. Microfibers can be used in the foam, slurry, or both, to prevent micro-cracking. Cementitious foams can be made without use of autoclave or lightweight aggregates to achieve enhanced compressive strength and thermal insulation properties that compare favorably with conventional foams and insulation materials at comparable densities.
US08277555B2 Coating composition
A coating composition which is excellent in crack resistance, alkali resistance and solvent resistance while having a high hardness and which is excellent in recoatability, anti-graffiti property, and removability of graffiti is provided. The coating composition according to the present invention comprises as the essential components, (a) a liquid organosiloxane compound which is a mixture of (a-1) a liquid organosiloxane compound having an alkoxy group content of 20 to 60% by mass and (a-2) a liquid organosiloxane compound having an alkoxy group content of 5% by mass or more and less than 20% by mass, in which an (a-1)/(a-2) mass ratio is 10/90 to 60/40, (b) an organometallic catalyst, (c) at least one compound selected from among alkoxy group-containing organosilane compounds having a primary or secondary amino group, amino-modified silicone oils, and amino group-containing organosiloxane compounds, and (d) at least one compound selected from among compounds having two or more glycidyl groups in one molecule, glycidyl group-containing silane compounds and glycidyl group-containing silicone oligomers.
US08277553B2 Plastics material
The present invention relates to a method of manufacturing a plastic material from a protein source, the method characterized by the following steps; i) treating a protein source such as blood meal with at least one denaturing agent, such as a combination of urea, sodium sulfite and sodium dodecyl sulfate, to break interactions between proteins or portions thereof, and ii) treating the denatured protein source with sufficient pressure and temperature to consolidate the denatured protein source into a plastic material.
US08277550B2 Yellow inkjet ink having improved print quality with porous photo media
The present invention relates to yellow dye-based inkjet inks having improved permanence when jetted onto porous photo media. The inkjet ink includes a mixture of at least two yellow dyes, at least three co-solvents comprising about 18% to about 24% of the composition of the ink by weight, a penetrant, at least one wetting agent, and water.
US08277548B2 Combined exhaust gas aftertreatment/air cleaner dust and ejector unit
A combined exhaust gas aftertreatment/dust ejector unit (10) is provided for use with a combustion process (14) and an air cleaner (16) of the combustion process (14). The unit (10) includes an elongate housing (30) containing an exhaust gas aftertreatment device (40) and having a radial exhaust gas outlet (34) to direct an exhaust gas flow (12) radially from the housing (30), and a dust ejector (60) including an ejector outlet (62) positioned in the exhaust gas outlet (34). The exhaust gas outlet (34) and the ejector outlet (62) have elliptical shaped cross sections (68,70), with the ejector outlet cross section (70) spaced inwardly from the exhaust gas outlet (34) to define a reduced flow area (72) for the exhaust gas flow (12) to accelerate the exhaust gas flow (12) past the ejector outlet (62).
US08277545B2 Method of reducing an amount of mercury in a flue gas
The subject matter disclosed herein relates to a method of reducing an amount of mercury discharged to an environment in a flue gas (12) generated by combustion of a fuel source. The method includes contacting the flue gas with a moist pulverous material upstream of a particle separator (24), mixing powdered activated carbon (PAC) in an amount between about 0.5 lb/MMacf and 10 lbs/MMacf with the flue gas (12) upstream of the particle separator (24), wherein the PAC interacts with at least a portion of mercury containing compounds in the flue gas (12), and separating the mercury containing compounds from the flue gas (12) containing the moist pulverous material and PAC, thereby reducing an amount of mercury in the flue gas (12).
US08277540B2 Apparatus and method for gas separation
Herein disclosed is an apparatus comprising (1) a porous rotor symmetrically positioned about an axis of rotation and surrounding an interior space; (2) an outer casing, wherein the outer casing and the rotor are separated by an annular space; (3) a motor configured for rotating the rotor about the axis of rotation; (4) a feed inlet positioned along the axis of rotation and fluidly connected with the interior space; and (5) a first outlet, wherein the first outlet is fluidly connected with the interior space. Herein disclosed is a system, comprising at least one disclosed apparatus. Herein disclosed is also a method of separating a feed gas into a first fraction and a second fraction, wherein the first fraction has an average molecular weight lower than the average molecular weight of the second fraction.
US08277537B2 Method of manufacturing ultra low carbon ferritic stainless steel
A method of manufacturing a ferritic stainless steel containing an ultra low level of carbon concentration in molten steel within time shorter than existing technology by controlling content, appropriate composition, and liquid-state fraction, etc., of Cr2 O3 in slag to maximize vacuum decarburization refining efficiency, the method comprising: tapping molten steel to a ladle in a non-deoxidized state after pre-decarburization and denitrification in an ARGON OXYGEN DECARBURIZATION refining furnace and then removing non-deoxidized slag; placing the ladle in a vacuum furnace, reducing pressure and then blowing-in oxygen gas from the upper of the molten steel through a lance; creating Al2 O3 by injecting Al at point of time of beginning of oxygen blowing; forming CaO—Al2 O3 —Cr2 O3 —MgO-based slag by injecting calcium oxide at point of time of completion of the oxygen blowing; and supplying inert gas through a porous plug on a bottom of the ladle.
US08277532B2 Air filter arrangement; assembly; and methods
An air filter arrangement is (300) disclosed. The air filter arrangement includes strips of media comprising corrugated sheets secured to facing sheets and forming inlet and outlet flutes secured to one another in a stack. Media pack arrangements including such stacked media with a molding arrangement to secure and seal opposite side edges of the media strips, are described. Also described are filter cartridges including such media pack (301) and air cleaners including the filter cartridges. Methods of assembly and use are also provided. Also, systems of use are described.
US08277531B2 Filter element
A filter element, and filter apparatus, include a filter pack, a seal member, and a seal support frame operatively connecting the seal member to the filter pack. The seal support frame includes an annular extension, which is preferably canted at an oblique angle to a longitudinal axis, for supporting the seal member. The seal support frame also preferably includes a first end thereof including the annular extension, and a second end thereof spaced from the first end thereof along the longitudinal axis, with the first and second ends of the seal support frame joined by a hub of the outer peripheral sidewall of the seal support frame to define a cavity within the seal support frame for receiving the filter pack. The first and second ends of the seal support frame, and the filter pack are preferably joined and sealed to one another by a single bead of adhesive.
US08277529B2 Filter medium and breather filter structure
Thermoplastic bicomponent binder fiber can be combined with other media, fibers and other filtration components to form a thermally bonded filtration media. The filtration media can be used in filter units, such as breather caps. Such filter units can be placed in the stream of a mobile fluid and can remove a particulate and/or fluid mist load from the mobile stream. The unique combination of media fiber, bicomponent binder fiber and other filtration additives and components provide a filtration media having unique properties in filtration applications.
US08277526B2 Filter dust collector
A filter dust collector is disclosed. The filter dust collector includes a housing, filter cloths fixed to an inside of the housing, a filter body part disposed inside the housing and having filter insertion holes, a compressed air supply part coupled to peripheries of the filter insertion holes, a transfer part connected to the filter body part to move the filter body part and the compressed air supply part in a longitudinal direction, a duct suction port formed on a side surface of the housing to suck air to be filtered, a supply port formed on a side surface of the housing to discharge filtered air, and a dust discharge port formed on a side surface of the housing, wherein the filter cloths are positioned at the filter insertion holes, the filter body part and the compressed air supply part move in the longitudinal direction, and the compressed air supply part sprays compressed air to the filter cloths.
US08277522B2 Mixed alcohol fuels for internal combustion engines, furnaces, boilers, kilns and gasifiers
Mixed alcohol formulas can be used as a fuel additive in petroleum, synthetic or bio-derived gasoline, diesel fuels, jet fuel, aviation gasoline, heating oil, bunker oil, coal, petroleum coke or as a neat fuel in and of itself. The mixed alcohol formulations can also be utilized as a thinning agent to improve the transportation of heavy petroleum crude oils or bitumen produced from tar sands. The mixed alcohol formulations can contain combinations of two or more, three or more alcohols, or blend of C1-C5 alcohols, or C1-C8 alcohols or higher C1-C10 alcohols in order to boost energy content. The primary benefits of mixed alcohols are increased combustion efficiencies, improved fuel economies, reduced emissions profiles and low production costs. These improved combustion efficiencies result in increased miles per gallon of blended fuel.
US08277521B2 Mixture of furfural and 5-(alkoxymethyl)furfural derivatives from sugars and alcohols
Accordingly, the current invention provides a method for the manufacture of a mixture of a furfural and a 5-(alkoxymethyl)furfural derivative by reacting a C5 and C6 sugar-containing starting material with an alcohol in the presence of an acid catalyst, followed by the hydrogenation and/or etherification of the mixture of furfural and 5-(alkoxymethyl)furfural to convert the aldehyde function of both 5-(alkoxymethyl)furfural and furfural into an alkoxymethyl function or methyl function.
US08277520B2 Method for producing negative electrode for non-aqueous electrolyte secondary battery, and negative electrode for non-aqueous electrolyte secondary battery
One aspect of the present invention pertains to a method for producing a negative electrode for a non-aqueous electrolyte secondary battery, which comprises a paste preparing step of kneading a mixture containing a negative electrode active material, a binder resin having a glass transition temperature within a range from 20 to 40° C. and a dispersion solvent to prepare a negative electrode material mixture paste, a paste applying step of applying the negative electrode material mixture paste controlled to a temperature which is at least 10° C. higher than the glass transition temperature of the binder resin on a current collector to form a coating film, a coating film drying step of drying the coating film to form a negative electrode precursor, and a rolling step of rolling the negative electrode precursor to prepare a negative electrode having a negative electrode material mixture layer.
US08277519B2 Hair treatment methods
A method of colouring a material, the method comprising the steps of: a)applying to the material a composition comprising a sulphur-containing nucleophile; and b)applying to the material a composition comprising a dye compound selected from a dye class other than the class of reactive dyes.
US08277517B2 Lightening agent having cationic acylpyridinium derivatives and certain amino acids
Method for lightening keratinous fibers, wherein a cosmetic carrier comprises (i) at least one oxidation agent, (ii) at least one acylpyridinium derivative of formula (I) and (iii) at least one amino acid comprising hydroxyl groups and/or the physiologically compatible salts thereof and/or the alkyl esters thereof.
US08277514B2 Fixing assembly
A component, e.g. a prosthetic ball and socket joint like an acetabular cup of a prosthetic joint, having a male or female location feature in a surface thereof for mutual interfit with a fixing member of a fixing assembly for securing the fixing member to the surface of the component and optionally for securing the component to a second component by means of a fixing screw.
US08277505B1 Devices for providing up to six-degrees of motion having kinematically-linked components and methods of use
The subject invention provides a modular six-degrees-of-freedom spatial mechanism for spinal disc prosthesis, with up to three independent rotational and up to three independent translational degrees-of-freedom. The prosthesis can maintain non-separable, and non-restrictive, mechanical linkage by establishing a linked series, or chain, of kinematic pairs (joints) between components. In embodiment, a superior plate links to a planar pair (two independent degrees of translational freedom), which links to spherical pair (three independent degrees of rotational freedom), which links to a prismatic pair (one independent degree of translational freedom), which links to an inferior plate, completing the jointed kinematic chain. The kinematic pairs can be lower (surface contact) or higher (point, line, and/or curve contact) order pairs, or combinations. The subject invention can enforce the kinematic constraints to realize the kinematic pairs and can also limit the range of operation of the degrees of freedom for each pair.
US08277501B2 Bi-stable bifurcated stent petal geometry
A stent has a substantially cylindrical tubular body with at least one expandable side branch that has a plurality of members. The plurality of members includes at least one first member having a first width and at least one second member having a second width, where the first width is greater than the second width. Each of the at least one first members and each of the at least one second members define a cell that has at least two stable cell geometries.
US08277495B2 Method and apparatus for treating a diseased nail
The invention generally relates to treating diseased nails, and more particularly to treating diseased nails using radiation and/or another form of energy to substantially deactivate the source of the disease. A nail treatment can be performed by a medical professional without the use of a dying agent or an exogenous chromophore, and the treatment can be effective at eliminating the source of the disease without subjecting a patient to adverse side effects or causing substantial unwanted injury to surrounding tissue.
US08277494B2 Bone anchoring device
A bone anchoring device includes an anchoring element having a shank to be anchored in a bone or a vertebra, a rod for connecting at least two anchoring elements, the rod being made of an elastic material. The bone anchoring device further includes a receiving part being connected to the shank for receiving the rod, a seat for the rod being provided in the receiving part the seat having a rod contacting surface, and a locking device cooperating with the receiving part for fixation of the rod in the seat. The locking device includes a rod contacting surface, wherein the rod contacting surface of the seat and/or the rod contacting surface of the locking device includes an engagement structure for engaging the rod, the engagement structure having an asymmetric cross section.
US08277491B2 Methods and devices for minimally invasive spinal fixation element placement
Minimally invasive methods and devices for introducing a spinal fixation element into a surgical site in a patient's spinal column are provided. In one embodiment, a dissection tool is provided for separating muscles along a muscle plane without causing damage to the muscles. The dissection tool can also include a lumen extending therethrough for receiving a guide wire. The tool allows the guide wire to be positioned relative to a vertebra, and once properly positioned, the tool can be removed to allow a spinal anchor to be delivered along the guide wire and implanted into the vertebra.
US08277484B2 Suture anchors
A suture anchor includes an outer sleeve having a longitudinal throughbore and defining leading and trailing ends and an insert positionable within the longitudinal throughbore of the outer sleeve. The insert defines at least one suture track for slidably supporting a suture whereby opposed free ends of the suture extend from the at least one suture track through the longitudinal throughbore to extend beyond the trailing end of the outer sleeve to be tensioned and secured relative to the tissue. The outer sleeve may include an external thread for threaded rotation and advancement into the tissue.
US08277480B2 Catch member for PFO occluder
Delivery (and recovery) devices and techniques for delivering an implant into a desired location within the body and catch systems for such implants. The devices and techniques relate particularly to, but are not limited to, a patent foramen ovale (PFO) occluder made from a polymer tube. A catch system maintains an occluder in a deployed configuration by holding it in a reduced axial length position. Some embodiments have a compressible tip. Some embodiments have temporary catching mechanisms.
US08277479B2 Self-opening filter with wire actuation
A distal protection device that may include a guidewire having a proximal end and a distal end, a filter disposed on the guidewire, the filter including filtering material and an expandable hollow coil, and a wire at least partially disposed within the coil, wherein the filter is actuatable from a closed position to an open position by reducing tension on the wire and methods of use thereof.
US08277477B2 Mechanically deployable upper airway stent
A mechanically deployable upper airway stent is disclosed along with a method of using same. The stent comprises a central tube having an inner chamber and openings on its surface. A linkage rod is housed within the central tube and is provided with branched spokes that pass through the openings. In the un-deployed state the branched spokes are contained within the central tube. Deployed spokes are preferably aligned in groupings along the central tube. The outer ends of the spokes of each grouping connect to a rib. The un-deployed stent is inserted into the nasal passageway and positioned relative to occluding anatomic structures. Upon deployment, the ribs along with web members extending between the ribs move outwardly from the central tube and press upon the tissues of the pharyngeal cavity. Spaces between the extended spokes permit the passage of air along the stent and maintain airway patency.
US08277476B2 Surgical instruments and procedures for stabilizing the beating heart during coronary artery bypass graft
The invention is methods and devices which a surgeon may use to stabilize the beating heart during a surgical procedure on the heart. Pursuant to the invention, a stabilizing device is introduced through an opening in the chest and brought into contact with the beating heart. By contacting the heart with the device and by exerting a stabilizing force on the device, the motion of the heart caused by the contraction of the heart muscles is effectively eliminated such that the heart is stabilized and the site of the surgery moves only minimally if at all. Typically, in separate steps, the surgeon contacts the heart with the stabilizing means, assesses the degree of movement of the anastomosis site, and exerts a force on the stabilizing means such that the contraction of the beating heart causes orgy minimal excess motion at the surgery site. By fixing the position of the stabilizing means in a configuration where the motion of the beating heart is effectively eliminated, the surgeon is able to stabilize the beating heart for the duration of the procedure. The stabilizing means may be attached to a rigid support or may be attached to a semi-rigid support which is rendered motionless mechanically, chemically, or by human intervention. In certain preferred embodiments, the stabilizing means is affixed to a semi-rigid support which is caused to become rigid, by any of a variety of techniques, such that the position of the stabilizing means becomes fixed by the support, and the heart remains substantially motionless for the duration of the procedure.
US08277475B2 Laparoscopic scissors
A laparoscopic scissor instrument can include a scissor assembly pivotally coupled to an elongate shaft. The scissor assembly can be formed of scissor blades having pivot posts thereon. The pivot posts can engage apertures on the elongate shaft, thus eliminating the need for a through-pinned pivot connection of the scissor blades. The scissor blades can also include actuation posts thereon. An actuation mechanism can include a slot to engage the actuation posts and open or close the blades of the scissor assembly. The scissor assemblies described herein can have a relatively low operational height such that they do not extend beyond a diameter of the elongate shaft during opening and closing of the scissor assembly.
US08277472B2 Deflector shield for use with multiple wound care devices
This invention discloses deflector shields to protect an operator from splashing from the use of hand-held ultrasound wound care devices. The deflector shield is for use with an ultrasound generator, ultrasound tip with a radiation surface and a fluid to serve as a coupling medium between the radiation surface and wound surface. The deflector shield is used to protect the operator from splashing fluid and removed tissue. The deflector shield consists of a hub portion and conical portion. The deflector shield is preferably transparent, disposable and easily installed. The deflector shield is preferably useable on several hand-held ultrasound wound care devices.
US08277468B2 Tissue reconfiguration
A medical instrument for engaging tissue includes a flexible shaft, a tissue piercing coil at a distal portion of the shaft, and a tissue stabilizer positioned over the shaft and biased in a distal direction such that as the tissue piercing coil enters tissue, the tissue stabilizer is urged against a surface of the tissue. A medical instrument for reconfiguring tissue includes a flexible shaft defining a lumen housing actuating controls, and a distal actuating assembly with a sealing portion configured to substantially seal the shaft lumen from contact with bodily fluids. A cartridge assembly includes first and second members configured for releasable attachment to a medical instrument, and a holder configured to receive the first and second members and to be released from the first and second members upon action of the first and second members attaching to the medical instrument.
US08277464B2 Bone suture
Devices and methods useful for suturing soft tissue to bone are disclosed. In one embodiment, a bone-suturing device is provided and can include a delivery needle, a delivery needle driving element, a capture needle, and a capture needle driving element. The delivery needle driving element and capture needle driving element can advance the delivery needle and the capture needle through soft tissue and into bone, respectively, and the paths of the delivery needle and the capture needle can intersect therein. The delivery needle can be adapted for holding a suture and the capture needle can be adapted for receiving the suture held by the delivery needle. An injection device can be provided to deliver an adhesive material into bone.
US08277463B2 Medical device and method of fixing internal organ
A medical device (1) includes a main body (2); a first piercing needle (4) provided slidably with respect to the main body (2); a first holding plate (61) adapted to hold the first piercing needle (4) and provided slidably on the main body (2); and a second holding plate (62) adapted to hold a second piercing needle (3) and detachably and movably mounted on the first holding plate (61), wherein the second holding plate (62) is mounted so as to move to the first holding plate (61) in a predetermined direction.
US08277462B2 Phacoemulsification device and method for operating the same
The invention relates to a phacoemulsification device, comprising: —a hand piece having a cutting tip for emulsifying a lens, wherein the tool holder is provided with piezoelectric elements for deflecting the cutting tip, —a regulator, the input of which is electrically connected to the tool holder, for receiving an actual value that is proportional to the voltage induced on the piezoelectric elements of the tool holder that is constantly oscillating on the natural frequency thereof, said regulator being suitable for comparing the actual value with a predetermined target value, thus determining an actuating variable, —a power amplifier, the input of which is connected to the regulator in order to receive the actuating variable, and the output of which is connected to the tool holder, wherein the tool holder may be actuated simultaneously with the receipt of the actual value and a power output to the tool holder being able to occur, such that a direct feedback coupling may be attained, thus enabling the tool holder to constantly oscillate at the natural frequency thereof with a deflection of the cutting tip corresponding to the actuating variable.
US08277459B2 Methods and devices for treating a structural bone and joint deformity
The various embodiments disclosed herein relate to implantable devices for the treatment of a structural bone and deformity. More specifically, the various embodiments include systems, devices, and methods for implantation of a flexible or tension band for treating such a deformity, including hallux valgus.
US08277456B2 Spinal-column distractor
A spinal-column distractor (10) comprises a first pusher plate (1) intended to bear on a vertebra, a second pusher plate (2) intended to bear on an adjacent vertebra, and a slide (3). The slide (3) is connected to the first pusher plate (1) via a scissor linkage (4), and shiftable by a threaded spindle to change a spacing between the first pusher plate (1) and the second pusher plate (2), while the second pusher plate (2) forms a track for the slide (3).
US08277455B2 Universal positioning device for orthopedic surgery and method of use thereof
A positioning device assembly for positioning a tool guide block for use in an orthopedic surgery on a bone element includes a positioning device having a block body with a reference surface adapted to abut the bone element, and first and second adjustment mechanisms that are independently operable. The first adjustment mechanism permits rotation of a tool guide block about a medial-lateral extending axis such as to provide flexion-extension angle adjustment and the second adjustment mechanism permits rotation of a tool guide block about an anterior-posterior extending axis such as to provide varus-valgus angle adjustment. The second adjustment mechanism includes both a coarse and a fine adjustment mechanism integral therewith. A tool guide block assembly mounted to the positioning device, the tool guide block assembly including a platform portion which is engaged to the block body of the positioning device and the tool guide block which is releasably engaged with the platform.
US08277449B2 Orthopedic external fixator and method of use
An orthopedic apparatus is provided for bridging a first bone unit to a second bone unit. The apparatus is demonstrated on a finger joint, wherein one of the bones and/or ligaments and/or tendons of the joint is/are injured. A method for implanting and using the apparatus also is presented. The apparatus includes a reformably deformable span portion which is generally circular and preferably rhombic. By deforming or reforming the span portion, it can be repositioned laterally, and/or it can be rotated to allow range of rotary motion so as to promote healing.
US08277448B2 External fixation
An orthopedic external fixation system may include a distal bar having a curvature that varies along its length, an uncurved proximal bar, a plurality of proximal embedding members, and a plurality of distal embedding members. The proximal and the distal embedding members, sized and shaped for embedding in bone, may attach directly or indirectly to the proximal bar and the distal bar, respectively.
US08277447B2 Single action tissue sealer
An endoscopic bipolar forceps includes a housing and a shaft, the shaft having an end effector assembly at its distal end. The end effector assembly includes two jaw members for grasping tissue therebetween. The jaw members are adapted to connect to an electrosurgical energy source which enable them to conduct energy through the tissue to create a tissue seal. A drive assembly is disposed within the housing which moves the jaw members. A switch is disposed within the housing which activates the electrosurgical energy. A knife assembly is included which is advanceable to cut tissue held between the jaw members. A movable handle is connected to the housing. Continual actuation of the movable handle engages the drive assembly to move the jaw members, engages the switch to activate the electrosurgical energy source to seal the tissue, and advances the knife assembly the cut the tissue disposed between the jaw members.
US08277441B2 Piezoelectric transducer
Devices and systems for transmitting information within a body are disclosed. An example system includes a signal generator configured for transmitting an acoustic interrogation signal, a sensor for sensing at least one parameter within the body and generating an electrical sensor signal, an acoustic transducer coupled to the sensor and configured to convert a received acoustic interrogation signal into an electrical signal, and a switching element adapted to modulate a reflected acoustic wave from the acoustic transducer based on the electrical sensor signal. The switching element is configured to controllably change the mechanical impedance of the acoustic transducer based a parameter of the electrical sensor signal, such as frequency.
US08277440B2 Implantable device for controlled, extended delivery of parathyroid hormone
Method and devices are provided for extended and controlled delivery of parathyroid hormone to a patient. The method includes implanting a medical device into the patient, the medical device comprising a substrate, a plurality of reservoirs in the substrate, a release system contained in each of the reservoirs, wherein the release system comprises parathyroid hormone; and controllably releasing a pharmaceutically effective amount of the parathyroid hormone from the reservoirs. The parathyroid hormone can be released intermittently, such as once daily over an extended period (e.g., two months, ten months, or more.). The device can further include reservoirs containing a bone resorption inhibitor or other drug for release. The devices are useful in delivering PTH for the treatment and prevention of bone loss, such as associated with osteoporosis.
US08277433B2 Ampoules
An ampoule made of plasties material, for liquid or suspension pharmaceuticals, has a reservoir linked to a removable head by a channel in a neck portion. The channel has a trap, thus located between its reservoir and the head, in the form of an elongated restriction and/or a bend to trap liquid or suspension which may settle during storage, and prevent either reaching the head.
US08277431B2 Absorbent article with multiple elastic areas
An absorbent articles, such as diapers, training pants, adult incontinence articles, feminine protection articles and the like having a specific elasticated topsheet comprising multitude of elasticated areas and one or more openings to receive e.g. feces, the elasticated areas being typically straight, but the elasticated areas operating jointly to provide a diverting-like elastic behavior, and the elasticated areas having optionally different elastic properties.
US08277430B2 Absorbent garment with strand coated adhesive components
An absorbent garment includes a body panel having a terminal waist edge, at least first and second layers terminating at the terminal waist edge and at least one elastic element disposed between the first and second layers. The body panel has at least first and second adhesive regions. The first adhesive region is defined by the at least one elastic element, which is strand coated with a first adhesive. The second region is defined by a control coating of a second adhesive applied between the first and second layers. In one embodiment, the first region has a greater sensory softness than the second region. In one embodiment, the body panel, in an unstretched condition, has a surface softness with a mean deviation of coefficient of friction less than about 0.020 in the first adhesive region.
US08277424B2 Needle-less syringe adapter
A needle-less syringe adapter has a tube, a resilient valve, a piercing member and an injection member. The tube has a body has a cavity and an outlet hole. The resilient valve is mounted in the cavity and has a chamber, a top slit and a bottom slit. The piercing conduit is mounted in the chamber, is driven to move when the resilient valve is compressed, selectively extends out through the top and bottom slits and has a through hole defined through the piercing conduit. The injection member is mounted on the tube and is selectively sealed by the resilient valve. The needle-less syringe adapter has excellent hermetical characteristics to prevent air infiltration and backflow of bloody and liquid medicine in a patient's blood vessel.
US08277423B2 Dosing device for an infusion system and method thereof
A dosing device for an infusion system comprises a dosing unit having a variable volume and at least one opening in fluid connection with the variable volume, through which opening the variable volume can be filled with a substance or the substance can be dispensed from the variable volume. The dosing device is operable in a first state for filling the substance from a supply conduit, in a second state for preventing filling and dispensing, or in a third state for dispensing through a dispensing conduit. No direct fluid connection exists between the supply conduit and the dispensing conduit at any time. Methods for dosing a substance with the dosing device.
US08277419B1 Catheter securement assembly
An assembly structured to secure a catheter, such as an IV tube to a predetermined portion of a patient's body such that the IV tube is anchored adjacent an entry site. A base is structured and configured to engage the predetermined body portion and includes an opening for exposure of and access to the entry site. A support member is selectively positionable at variable locations relative to the opening in adjacent relation to the entry site such that the IV tube is mounted on an exterior or exposed portion of the support member so as to access the entry site through the opening and eliminate any type of adhesive strip or like connector contacting or being secured to the patient's skin.
US08277418B2 Ophthalmic valved trocar cannula
In various embodiments, a trocar cannula may be configured for insertion into an eye to facilitate insertion and removal of instruments during surgery. The cannula may be affixed to an overcap (to inhibit rotation of the overcap relative to the cannula) that includes a seal. In some embodiments, the seal may be overmolded into the overcap or may include a wafer that is fixed between the cannula and the overcap to inhibit rotation relative to the cannula and the overcap. In some embodiments, the cannula and overcap may snap together through a tab/slot interface in a permanent fashion such that the cannula and overcap may not be separated without damaging the cannula or overcap. In some embodiments, a vent cannula may be receivable in the slit of the seal for allowing fluids to vent from the eye through the cannula (which may include an indentation to frictionally engage the vent).
US08277416B2 Powerhead of a power injection system
A contrast media injection system includes detects the absolute position of the syringe ram using a non-contact sensor. A series of magnets and Hall-Effect sensors may be used or an opto-reflective system. Illuminated knobs that are connected to the drive mechanism for the syringe ram rotate with the drive and provide visual feedback on operation through the illumination. Analog Hall-Effect sensors are used to determine the presence or absence of magnets that identify the type of faceplate being used. The faceplates include control electronics, connected to the powerhead through connectors, which may be interchangeably used by the two faceplates. The faceplate electronics include detectors for automatically detecting the capacity of pre-filled syringes. Additional features include using historical data to provide optimum pressure limit values during an injection protocol, a removable memory device for storing and transferring information such as injection protocols and injector statistics, and password protection of such protocols.
US08277412B2 One shot injector with dual springs
The present invention relates to a medical delivery device comprising a generally elongated housing, a container containing medicament to be delivered, a drive means capable of acting on said container for expelling said medicament, wherein said drive means comprises at least two force spring means arranged between a fixed part of the device and a movable part of the device.
US08277411B2 Needle device
A needle device for penetrating body tissues while substantially reducing the risk of damage to blood vessels and body organs by using visual control of the operative tip during insertion and the procedure, is disclosed herein. The needle device of the present invention has a large and diverse applicability to a number of medical procedures by enabling internal visual inspection of body tissues and cavities during treatment without open surgery or supplemental penetrating or visualization devices.
US08277410B2 Methods and apparatus for inhibiting introduction of air into the vasculature during a percutaneous procedure
Apparatus and methods for inhibiting the introduction of air into the body during a percutaneous procedure. The apparatus may include an instrument passage lumen defining a degassing region with a degassing region distal end and a degassing region proximal end, a fluid inlet port at the degassing region distal end, and a fluid outlet port at the degassing region proximal end. So configured, fluid will flow only from the degassing region distal end to the degassing region proximal end.
US08277405B2 Post-coital feminine hygiene device
A feminine hygiene device to wipe seminal and other fluids from the vagina after sexual intercourse.
US08277395B2 Lumen measurement devices and related methods
Various embodiments of a measurement device used to measure a size of a lumen and related methods of use are disclosed. For example, the device may include a proximal handle, a distal member including a radially expandable portion, a control member connecting the proximal handle to the distal member, and a measurement indication member for displaying a value indicative of a size of the expandable portion. The radially expandable portion may be configured to expand from a contracted state to an expanded state to measure the size of a lumen.
US08277394B2 Multi-button biopsy device
A handheld biopsy device comprises a needle, cutter, and body. The cutter is movable relative to the needle to sever tissue protruding into a transverse aperture of the needle. The body includes a cutter actuation mechanism, at least two trigger buttons, and a control module. The biopsy device is configured such that the at least two trigger buttons are selectively enabled and disabled. A selectively enabled trigger button is operable to activate the cutter actuation mechanism. A selectively disabled trigger button is not operable to activate the cutter activation mechanism. The enabled trigger button may be selected electronically, such that the control module receives a user's button selection input and enables or disables the trigger buttons accordingly. Alternatively, the body may include movable covers to selectively cover or expose trigger buttons in accordance with the user's preference. The biopsy device may thus accommodate different operators having different gripping styles.
US08277393B2 Biopsy apparatus
A disposable tissue removal device comprising a cutting element mounted to a handpiece. The cutting element includes an outer cannula defining a tissue-receiving opening and an inner cannula concentrically disposed within the outer cannula. The outer cannula has a trocar tip at its distal end and a cutting board snugly disposed within the outer cannula. The inner cannula defines an inner lumen that extends the length of the inner cannula and terminates in an inwardly beveled, razor-sharp cutting edge. The inner cannula is driven by both a rotary motor and a reciprocating motor. At the end of its stroke, the inner cannula makes contact with the cutting board to completely sever the tissue. An aspiration vacuum is applied to the inner lumen to aspirate excised tissue through the inner cannula and into a collection trap that is removably mounted to the handpiece. The rotary and reciprocating motors are hydraulically powered through a hydraulic circuit. The hydraulic circuit includes a foot pedal that initiates aspiration vacuum, rotary motion and reciprocation of the inner cannula. The hydraulic circuit is configured so that the inner cannula closes the tissue-receiving opening before the foot pedal is depressed and automatically after the foot pedal is released.
US08277390B2 Method for automatic non-cooperative frequency specific assessment of hearing impairment and fitting of hearing aids
A method and device for automatically assessing loss of hearing sensitivity and compression (recruitment) with user defined frequency resolution by means of extrapolated DPOAE I/O functions and ABRs as well as for automatically fitting hearing aids without any cooperation of the subject tested using a device having a display screen attached to a handheld device generating and collecting otoacoustic emission signals and brain stem response signals into a programmed with a clinical audiogram with fitting parameters for hearing aids calculated on the basis of assessed hearing threshold and compression and identifying the type of hearing required for the individual.
US08277388B2 Blood rheology measuring apparatus
A blood rheology measuring apparatus has a measuring portion for measuring a flow velocity of the blood flowing in a blood vessel of a person in a mode of a Doppler shift signal by transmitting and receiving a wave to and from a surface of the person's skin. An information processing portion calculates an intensity at each of frequency components of the Doppler shift signal, extracts a maximum frequency in a signal at an intensity level equal to or larger than a threshold in the histogram or a maximum frequency when an integrated value from a low frequency component reaches a predetermined rate of a total thereof in the histogram, and provides a temporal change waveform of the extracted frequency. The blood rheology is analyzed by an area value of a portion at and above a line connecting a minimum value of one pulse waveform and a minimum value of a successive pulse waveform of the frequency waveform.
US08277384B2 System and method for in vivo measurement of biological parameters
A system, method and medical tool are presented for use in non-invasive in vivo determination of at least one desired parameter or condition of a subject having a scattering medium in a target region. The measurement system comprises an illuminating system, a detection system, and a control system. The illumination system comprises at least one light source configured for generating partially or entirely coherent light to be applied to the target region to cause a light response signal from the illuminated region. The detection system comprises at least one light detection unit configured for detecting time-dependent fluctuations of the intensity of the light response and generating data indicative of a dynamic light scattering (DLS) measurement. The control system is configured and operable to receive and analyze the data indicative of the DLS measurement to determine the at least one desired parameter or condition, and generate output data indicative thereof.
US08277379B2 Methods and apparatus for the treatment of menometrorrhagia, endometrial pathology, and cervical neoplasia using high intensity focused ultrasound energy
A probe having a high intensity focused ultrasound (HIFU) transducer is positioned in a female patient. The HIFU transducer is deployed within the vagina of the patient outside of the cervix and uterine cavity and is configured to direct HIFU energy to a treatment site within the uterus of the patient. An imaging component positioned relative to the patient images a portion of the patient's uterus that includes the treatment site to help guide the delivery of the HIFU energy to the treatment site. A liquid medium may be infused into the uterine cavity of the patient where it is maintained during imaging and delivery of the HIFU therapy. The HIFU transducer produces a thermal heating of tissue at a focus within the treatment site to initiate necrosis of the tissue. The location of the focus is controlled in accordance with an image obtained by the imaging component.
US08277376B2 Process and a device for surgical treatment of rectal and haemorrhoidal prolapse
A process for surgical operations on a rectal/haemorrhoidal prolapse comprises stages of realising, in the anal canal, at least a first circular stitching at a first portion of a haemorrhoidal prolapse; realising at least a second circular stitching in a second portion of the haemorrhoidal prolapse, and nearing the first circular stitching and the second circular stitching in order to create a constriction of the haemorrhoidal prolapse. The invention also relates to a device, preferably for actuating the process, which comprises a hollow divaricator (17) having a prevalent development direction along a longitudinal axis (Z) and being insertable in a patient's anal orifice. The device further exhibits a window (29) defining an operational area and creating a communication between a cavity (17b) internal of the divaricator (17) and a portion of haemorrhoidal prolapse. The device further comprises means for opening and closing (31) the window (29).
US08277369B2 Bearing and bearing assembly for umbilicus of a fluid processing system
A one-piece bearing is provided for use with a fluid processing assembly of the type having an umbilicus, a bearing support, a gimbal received within the bearing support, and a liner at least partially received within the gimbal. The bearing is secured to a midsection of the umbilicus and adapted to be at least partially received within the liner. An inner surface of the bearing engages the umbilicus while an outer surface of the bearing engages at least a portion of the liner for rotation relative to the liner.
US08277364B2 Clutch control device for hydraulically driven vehicle
A first motor 3 and a second motor 4 of variable displacement type are in parallel to each other connected to a hydraulic pump 2 in a closed circuit, through which the output torque from the first motor 3 is transmitted to an output shaft 6. A clutch control unit 10 controls a clutch device 15 as: when the engine speed is N1, which is the case where the accelerator pedal is fully depressed, the clutch is disengaged at the vehicle speed v1. When the engine speed is N3(
US08277363B2 Method and apparatus to control temperature of an exhaust aftertreatment system for a hybrid powertrain
An internal combustion engine is fluidly connected to an exhaust aftertreatment system and operatively connected to an electro-mechanical transmission to transmit tractive power to a driveline. The engine is controlled during an engine operating cycle by determining a temperature of the exhaust aftertreatment system and adjusting power output of the engine based upon the temperature of the exhaust aftertreatment system and a preferred temperature range of the exhaust aftertreatment system. The electro-mechanical transmission is controlled to transmit tractive power to the driveline to meet an operator torque request based upon the adjusted power output of the engine.
US08277361B2 Control apparatus for transmission
A control apparatus of a transmission for a vehicle, which includes an electric generator provided between an engine and the transmission and regenerating electricity when torque is transmitted from a drive shaft of the vehicle via the transmission in a braking condition, includes a releasing speed measuring unit, an up-shifting operation allowing unit and an up-shifting operation restraining unit. The releasing speed measuring unit measures a releasing speed of an accelerator pedal. The up-shifting operation allowing unit is applied to allow an up-shifting operation under the accelerator pedal being released when a releasing speed of the accelerator pedal is lower than a first threshold value. The up-shifting operation restraining unit is applied to restrain the up-shifting operation under the accelerator pedal being released when the releasing speed of the accelerator pedal is equal to or lower than the first threshold value.
US08277358B2 Epicyclic reduction gear with multiple modular stages for tubular motor reducers operating winding roller shutter, roller shades and the like
The present invention relates to an epicyclic reduction gear with multiple modular stages (M1, M2, M3) for tubular motor reducers operating winding roller shutters, roller shades and the like. Each reduction stage is provided with a central toothed hub (1) on one side and a central splined hub (5) on the other side, in compliance with the said hub, the hub (8) of a stage being designed to be coupled with a pin (5) of the adjacent stage.
US08277357B2 Multi-speed transmission having three planetary gear sets
A transmission is provided having an input member, an output member, three planetary gear sets, a plurality of coupling members and a plurality of torque transmitting devices. Each of the planetary gear sets includes first, second and third members. The torque transmitting devices include clutches and brakes.
US08277354B2 Multi-speed transmission
A transmission is provided having an input member, an output member, four planetary gear sets, a plurality of coupling members and a plurality of torque transmitting devices. Each of the planetary gear sets includes first, second and third members. The torque transmitting devices include clutches and a brake. The torque transmitting mechanisms are selectively engageable in combinations of at least two to establish at least eight forward speed ratios and at least one reverse speed ratio between the input member and the output member.
US08277353B2 Transmission system
A sun gear of a first planetary gear train is connected to an input shaft. A carrier of the first planetary gear train is connected to a sun gear of a second planetary gear train and to a first pump/motor. A ring gear of the first planetary gear train is connected to a second pump/motor, and a ring gear of the second planetary gear train is connected to an output shaft. A first clutch is provided for engaging and disengaging a carrier of the second planetary gear train and the ring gear of the first planetary gear train with and from each other, and a second clutch is provided for engaging and disengaging the carrier of the second planetary gear train and a fixed end with and from each other.
US08277351B2 Device for an electromechanical hoisting machine, especially for use when drilling oil and gas wells
A device for an electromechanical hoisting machine (10) with driving gears (6) in engagement with rack rails (5) fixed to a steel structure (1). The hoisting machine is driven by electromotors (8) which transmit torque to the driving gears (6) through the gearing (11), the shaft (15) and further the bevel gear drives (14, 16, 17) and gears (18, 19) to the driving gears (6) in engagement with rack rails (5). To achieve flexible load distribution on the driving gears (6), differential gears (12) supported on projecting shaft journals (20) connected to the main shaft (15) are arranged between the bevel gear drives (16).
US08277349B2 Actuation system
An actuation system includes a prime mover, a mechanical option module, an actuator, and a controller. The prime mover includes a drive shaft. The mechanical option module includes a housing, an input shaft coupled to the drive shaft, an output shaft, and a planetary gear module. The planetary gear module includes a sun gear coupled to the input shaft, a planet carrier coupled to the output shaft, an outer ring, and planet gears meshed with the sun gear and the outer ring. The application-specific module is connected to the housing and configured to selectively influence movement of the outer ring of the planetary gear module. The actuator includes an actuator input shaft coupled to the output shaft of the mechanical option module. The controller controls an operation of at least one of the prime mover, the mechanical option module, and the actuator.
US08277348B2 Clutched damper for a belt tensioner
A tensioner including a support structure defining a pivot axis, an arm coupled to the support structure for rotation about the pivot axis, and a damping mechanism. The arm includes a cup having the damping mechanism seated therein. The damping mechanism includes a first tensioner component that is generally cup-shaped and has first ramp features on the rim thereof, a second tensioner component having second ramp features, and a damper spring coupling the first tensioner component to the second tensioner component. The first tensioner component is rotatable with the arm and the second tensioner component is non-rotatable. The damper mechanism has the first ramp features aligned with the second ramp features and rotation of the first tensioner component in a first direction moves the first ramp features relative to the second ramp features and translates the first tensioner component into damping engagement with the arm.
US08277347B2 Tensioner
The present invention is directed to decrease the impact sound of the ratchet mechanism generated at the time of piston retraction. The tensioner includes a piston 3 slidable in the piston bore 2a of the housing 2 and an expandable circlip member 5 engageable with the engagement groove 3a of the piston 3. The piston bore 2a has a guide groove 20 formed therein that has front and rear stop surfaces 20a, 20b adapted to contact the circlip member 5. The engagement groove 3a is formed by a round seat portion S0 that the circlip member 5 is adapted to seat, a piston-retraction restricting portion S0S1 that is formed on the front side of the round scat portion S0 and a piston-advance permitting portion S0S2 that is formed on the front side of the round seat portion S0. The piston-retraction restricting portion S0S1 permits the circlip member 5 to travel a short distance toward the front side along the rear side stop surface 20b to allow for an enlargement of the circlip member 5 and to restrict retraction of the piston 3 when the piston 3 retracts and the circlip member 5 contacts the rear side stop surface 20b of the guide groove 20.
US08277346B2 Low profile rear derailleur
A bicycle rear derailleur comprises a base member; a movable member that supports a chain guide including a first pulley that rotates around a first pulley axis, wherein the pulley has a pulley plane; and a first linking member coupled between the base member and the movable member so that the chain guide moves laterally relative to the base member between a first lateral position and a second lateral position. The pulley plane intersects the first linking member when the chain guide is located at a first position between the first lateral position and the second lateral position.
US08277343B2 Bat constructed for striking a ball
A hybrid material bat comprises an elongate shaft, a reinforcing member, a barrel body and a grip body. The shaft is made of rigid materials and includes a front portion, an intermediate portion and a rear portion. The barrel body is made of materials with good striking performance and includes a striking section for striking, impacting, or hitting and a mid-section. The grip body is made of resilient materials with good shock absorbing property, and has a front end and a terminal end. The reinforcing member is made of rigid materials and disposed on a distal end of said front portion of said shaft. The barrel body intimately surrounds the front portion of the shaft and the reinforcing member. The grip body intimately surrounds the rear portion of the shaft.
US08277338B2 Golf ball and method for designing same
A golf ball includes noncircular dimples having smooth bottom surfaces; a method for designing the golf ball is disclosed. A noncircular dimple DNC has a border line which is a boundary line on the surface, the boundary line formed by connecting segments at some connecting points. The segments include at least one type of line segments LS and smoothly curved segments CS. A bottom surface BS of the noncircular dimple DNC includes at least five facets formed of at least five curved reference lines RC, each connecting a reference point A and one of at least five border points B, and each being tangential, at the reference point A, to a reference plane RP inside a virtual sphere having the radius of the ball, the reference point A set on the reference plane RP, the border points B set respectively at positions on the boundary line excluding the connecting points.
US08277337B2 Iron head
An iron head is provided with a recess portion provided in an upper portion of a backside surface thereof, and a protruding portion provided at a lower portion of the backside surface. A first hollow portion is provided on a heel side from a bottom surface of a recess portion to a sole surface; and a second hollow portion is disposed on a toe side. The first hollow portion and the second hollow portion do not exist behind a sweet area. The first hollow portion and the second hollow portion may be filled with a shock absorber formed of a rubber or an elastomer.
US08277330B2 Connecting arrangement between shaft journal and constant velocity rotary joint
A connecting arrangement between a shaft journal and a constant velocity rotary joint having a joint inner part and a joint outer part, in which the shaft journal engages in a rotationally fixed manner in one of the joint parts, and the shaft journal and the constant velocity rotary joint are two components. At least one clamping sleeve is provided which is axially secured on one of the components, and which includes at least one elastic element which can lock in place in a contour of the other component.
US08277328B2 Electromuscular incapacitation device and methods
Incapacitation of a mammalian subject results from the application of a pulsed, low-power electric waveform. The waveform is applied to the subject at a frequency and over a time period sufficient to induce involuntary muscular contraction. Additionally, the contraction causes limited lactic acid production and is non- or minimally-injurious to the subject's tissues. A device utilizing such a waveform is designed to control or otherwise subdue an individual.
US08277326B2 Removable player station and locking mechanism for electronic games
A removable player station and locking mechanism. In one implementation, a removable player station allows quick and secure replacement, swapping, and upgrade of a modular player station component for electronic games. In one context, an electronic game table may employ multiple of the removable player stations, each secured with a locking mechanism and a common or a unique lock. In one implementation of a latching mechanism, a pivotable cradle attaches to the electronic game or game table and seats the removable player station through a pivoting motion that also brings the cradle into a locking position. When the pivotable cradle is opened from the locking position, the cradle lifts the removable player station from the game or tabletop for easy manual removal. The accessible part of the locking mechanism may be located under an electronic game tabletop away from view of the players.
US08277325B2 Game achievements system
Systems and method for providing a game achievements system where players are rewarded with game achievements based on mastering certain in-game facets of the games they play. Each game achievement may be conveyed in a profile as a badge or trophy, title, description, date, etc. Players may also accumulate points based on game achievements. A display interface may be made available such that a player may see his achievements and total points, as well as those of others.
US08277324B2 System and method for collecting and using player information
A distributed computer system is provided for collecting player information. Further, a scoring system is provided that rates a player based on one or more elements of the collected information. Players may be rated with respect to a number of characteristics. Responsive to a determined rating or score, action may be taken by the distributed system with regard to the player. For instance, the player may be provided a complimentary offer, provided an award, and invitation to come to a gambling location, presented an advertisement, or other action may be performed involving the player. Further, the distributed computer system may permit a player to manage their frequent player accounts and receive complimentary offers based on a set of criteria specified by the player.
US08277315B2 Game simulation based on current events
A video game includes: (i) a graphic user interface that presents a user a simulation of real-life events; (ii) a content database containing a collection of actual photos and videos of real-life events; (iii) a simulation engine that, presents a plurality of possible actions to the user, receives a selection of at least one of the actions from the user, identifies at least one photo or video in the database that is associated with the user-selected action, and presents the user with a result in response to the selection, wherein the result includes the identified photo or video; (iv) a content update module that receives updated photo or video content from one or more content distributors, creates an association element for the updated content and an available action in the game, and includes the updated content and association element in the content database; and (v) a scoring module.
US08277314B2 Flat rate wager-based game play techniques for casino table game environments
Various techniques are disclosed for operating, at a live casino gaming table, a table game having a flat rate play session costing a flat rate price. In one embodiment, the flat rate play session may span multiple plays on the gaming table over a pre-established duration. In at least one embodiment, a given gaming table may be operable to simultaneously or concurrently host both flat rate game play and non-flat rate game play to different players at the gaming table. In one embodiment, the gaming table may include an intelligent multi-player electronic gaming system which is operable to identify price parameters, and/or operable to determine a flat rate price of playing a flat rate table game session based on those price parameters. Additional aspects relate to automated start/stop/suspend/end of flat rate table game sessions.
US08277313B2 Gaming machine and playing method thereof, which qualifies player to join special game through chance game run at the same time base game is run
A gaming terminal includes a base game offering a chance of winning a payout according to a predetermined combination; a chance game offering a chance of obtaining a chance flag which qualifies a player to join a special game offering a chance of winning a higher payout than the base game; a terminal storage unit storing the number of chance flags; a terminal display which displays images of the base game, the chance game, and the special game; and a terminal controller. The terminal controller performs the steps of: running the base game and the chance game at the same time; determining and awarding a payout according to a result of the base game; determining and awarding the number of chance flags according to a result of the chance game; accumulatively storing in the terminal storage unit the number of chance flags awarded; awarding a payout determined according to a result of the special game which is run when the number of the chance flags stored in the terminal storage unit equals or surpasses a predetermined number; and awarding a determined special payout, when a value obtained by subtracting a sum of one or more payouts of the special game from a sum of one or more game values inserted from the game value insertion unit equals or surpasses a predetermined value.
US08277308B2 Gaming device having independent reel columns
A gaming device having unisymbol display reels, wherein each symbol on a display of the gaming device represents or is included on a different reel. The structure of the paylines of the gaming device is such that the gaming device can include different reel strips having different winning symbols or different proportions of winning symbols, while still maintaining payout symbols and payout combinations that have uniform odds and uniform payouts.
US08277303B2 Method of operating and displaying a meter feature using evolving symbols in a line game
Method of operating a line game wherein the values of a meter are displayed as different statuses of an evolving symbol. The meter gathers symbols, combinations of symbols, events that are dependent of the game outcome (like winning or losing outcomes, prizes, etc.), or events that are independent of the game outcome (like spins, bet values, lengths of time, etc.). The evolving symbol statuses are used in the line game to trigger features ranging from a wild symbol to a bonus payout which can take the form of a progressive jackpot.
US08277302B2 Method and apparatus for providing a bonus to a player
A method, system, device and computer readable medium are described, in which a wagering game and a secondary game may be provided at a gaming device, wherein the secondary game comprises detecting an occurrence of a trigger; determining, responsive to the trigger, a player number based on a first criterion; determining, responsive to the trigger, a match number based on a second criterion; and determining if the match number meets a third criterion with respect to the player number.
US08277300B2 Poker game system and method with cards selection
A method of playing a poker game comprising the steps of: providing a number N of card-boxes at a player's instance; providing for selection of at least one of a predetermined number n of card-boxes from said number N of card-boxes as a player's card-box selection; dealing a card to each of the number N of card-boxes; determining a player's hand based on the cards of the player's card-box selection; dealing as dealer's cards a number of cards determined by the number of player's card-box selection; determining a dealer's hand based on the dealer's cards; and determining a winning hand over the player's and dealer's hand according to a predetermined paytable.
US08277295B2 Ventilation member and ventilation structure
A ventilation member (1) comprises a support body (2), a ventilation membrane (10), and a cover part (3). The support body (2) includes a bottom surface portion (4) connected to the casing (50) and a side surface portion (5) on which the ventilation membrane (10) is installed. A first opening (4h) is formed in the bottom surface portion (4), and a second opening (5h) is formed in the side surface portion (5). The ventilation membrane (10) is installed on the side surface portion (5) so as to close the second opening (5h). The cover part (3) has a cylindrical side wall part (3b) that circumferentially surrounds the support body (2) in such a state that the support body (2) is assembled therein. The position of the second opening (5h) to be formed in the side surface portion (5) of the support body (2) is adjusted so that the ventilation membrane (10) is protected when the membrane faces the cylindrical side wall part (3b).
US08277294B2 Method and device for slitting a chicken leg
A method and device for slitting a chicken leg which is suspended at its ankle joints from a carrier that forms part of a train of carriers that are movable in a processing line that passes the device is provided. A positioning step is applied for placing the leg in a suitable position for cutting the leg. Subsequently in a stabbing step a knife is brought into engagement with the leg. The stabbing step is followed by a slitting step in which the knife is moved along the leg so as to provide a slit in the longitudinal direction of the leg in order to enable a subsequent deboning step of the leg. In the positioning step a first pressing organ engages the leg in the vicinity of the knee joint so as to press the leg against a movable supporting surface for the leg that is positioned opposite to the pressing organ. A second pressing organ engages the leg from the side so as to push the leg into a substantially straight orientation of the drum and the thigh with respect to each other.
US08277292B2 Inline handheld power tool
A powerhead for a hand held power tool includes a powerhead assembly, the powerhead assembly being operably couplable to a hand held motive source, the powerhead assembly having a rotatable implement, the implement being selectively rotated by the motive source when the motive source is operably coupled to the powerhead assembly, the implement further being rotatable about an implement axis, the implement axis being disposed transverse to a powerhead assembly longitudinal axis, the implement axis intersecting the powerhead assembly longitudinal axis. A hand held power tool and a powerhead of forming a powerhead for a hand held power tool are further included.
US08277291B2 Abrasive slotted disc with controlled axial displacement of a workpiece
Apparatus and method for sharpening a workpiece, such as a cutting tool. An abrasive disc is rotatable about a disc rotational axis and includes a plurality of spaced apart, radially disposed apertures extending therethrough from a first surface to an opposing second surface of the disc. The first surface is configured to facilitate sharpening of a workpiece by contacting engagement of the workpiece against an abrasive layer adjacent the first surface between adjacent first and second apertures of said plurality. The first surface further induces controlled axial displacement of the workpiece away from the disc as the second aperture approaches the workpiece during disc rotation. The first surface is preferably concave so as to extend into the disc between each adjacent pair of the apertures. Alternatively, the first surface is provided with different compressibilities to induce the controlled axial displacement of the workpiece.
US08277290B2 Polishing pad and polishing device
A polishing pad used in semiconductor polishing process is provided in the present invention and a pressure sensitive adhesive is used to couple the polishing pad. The polishing pad includes a substrate, and the substrate includes a polishing surface and a reverse surface corresponding to the polishing surface. The polishing pad is characterized by: a pressure sensitive adhesive formed on the reverse surface of the substrate and used to couple with a bottom layer, and the horizontal adhesion of the pressure sensitive adhesive is higher than the vertical adhesion of the pressure sensitive adhesive.
US08277285B2 Method of maintaining a constant grinding process
Method of grinding cylindrical gears with a threaded grinding wheel wherein the amount of grinding wheel material utilized during shifting remains constant as the wheel diameter decreases, for example, due to dressing. The amount of grinding wheel shifting is adjusted as the grinding wheel diameter decreases.
US08277282B2 Ultrasonic trimming apparatus and ultrasonic trimming method
An ultrasonic trimming apparatus is composed of an articulated robot, a cutting apparatus, and a grindstone. The cutting apparatus is composed of an ultrasonic oscillator which is supported by the end portion of the articulated robot, a cutter blade which is supported by the ultrasonic oscillator, and a workpiece securing portion which secures a workpiece. The grindstone serving as a grinding member is disposed within the movable range of the cutter blade driven by the robot and is placed in a position at which the cutter blade can pressure contact the cutter blade. The cutter blade is ultrasonically vibrated by the ultrasonic oscillator and is ground while being pressed against the grindstone by means of the articulated robot. The ultrasonic trimming apparatus efficiently cuts a sheet material composed of soft material such as plastic, fabric, or rubber, a composite material, or a material containing glass fiber by means of an environmentally conscious method even when the material has a three-dimensional shape.
US08277277B2 Blasting method and blasting machine
In blasting with an abrasive containing liquid to confer elasticity, the abrasive from which liquid evaporates in the course of continuance use is uniformly supplied with liquid. Liquid for swelling an elastic abrasive is sprayed in an air flow for transporting the abrasive in a blasting machine 1 including an abrasive-recovery duct 91 communicating between a bottom of a cabinet 2 and an abrasive-recovery tank 3, the abrasive-recovery tank 3, a compressed gas before being introduced into a blasting gun 8, and so forth. Since the abrasive being transported in the air flow is separated into individual particles, each abrasive can be uniformly supplied with liquid.
US08277274B2 Apparatus and methods for use of refractory abhesives in protection of metallic foils and leads
A device having a quartz or glass body forming a chamber hermetically sealed by one or more pinch seals formed in the body wherein a metallic foil provides an electrical connection through a pinch seal. A method is provided for protecting a portion of the metallic foil from corrosion prior to forming the pinch seal by coating at least a portion of the foil with a film comprising silica, and applying a refractory abhesive to at least a portion of the film.
US08277272B1 Flotation apparatus
A flotation apparatus including a frame configured to support a snorkeler lying in a prone position. A plurality, preferably six, of elongated arms are each pivotally attached at a proximal end thereof to the frame with a buoyant float positioned on a distal end of each arm for enhanced stability. Preferably, a propulsion apparatus is mounted to the frame and a control apparatus for operating the propulsion apparatus in a prone position is provided.
US08277264B2 Contact having independently deformable spring portions and connector including the contact
A contact is formed of a single metal sheet. The contact includes an upper spring portion configured to press an upper surface of a plate-like connection target in a downward direction and a lower spring portion configured to press a lower surface of the plate-like connection target in an upward direction. The lower spring portion is deformable independently of the upper spring portion.
US08277262B2 PCB connector
The invention relates to a PCB connector (1), comprising a housing (2) and a plurality of contact elements (3), every contact element (3) having a contact for connection to wires and a contact for connection to a printed circuit board. housing (2) is configured as one piece, the contact elements (3) being captively snap-locked in the housing (2).
US08277261B2 Electrical connector
An electrical connector includes a signal blade including a first base member formed of an insulation material and a signal circuit portion formed on the first base member; a power source blade including a second base member formed of an insulation material and a power source circuit portion formed on the second base member, said power source blade further including an engaging protrusion; and a holding member formed of an insulation material and including a blade holding hole so that the engaging protrusion engages an inner surface when the power source blade is inserted into the blade holding hole.
US08277255B2 Interconnect member for an electronic module with embedded components
An interconnect member is provided for electrically connecting an electronic module to a printed circuit. The interconnect member includes a substrate having a module side and an opposite circuit side. Module contacts are held by the substrate. The module contacts are arranged within an array along the module side of the substrate. The module contacts include module mating interfaces that are configured to be electrically connected to the electronic module. Circuit contacts are held by the substrate. The circuit contacts are arranged within an array along the circuit side of the substrate. The circuit contacts include circuit mating interfaces that are configured to be electrically connected to the printed circuit. Electrical components extend between and electrically connect corresponding module contacts to corresponding circuit contacts to provide electrical paths for electrical signals transmitted between the module and circuit contacts. At least one of the electrical components modifies the corresponding electrical signal transmitted along the electrical path between the corresponding module and circuit contacts.
US08277253B2 Electrical connector and circuit board assembly
An electrical connector adapted to electrically connect with a plug-type electrical connector of the periphery equipment of the computer. The electrical connector includes a housing, an insulating body, a plurality of first conductive terminals, and a plurality of second conductive terminals. The insulating body having a frame and a terminal block positioned within the frame. The plurality of first conductive terminals positioned along a first surface of the terminal block, while the plurality of second conductive terminals are positioned along a second surface of the terminal block. The plurality of first conductive terminals include a first ground terminal, while the plurality of second conductive terminals include a second ground terminal, and the first ground terminal and the second ground terminal share one free end leading out of the electrical connector.
US08277252B2 Electrical connector assembly
An electrical connector assembly is provided with a shielding cage member having an upper port and a lower port configured to receive pluggable modules therein. The cage member has a front mating face that has openings to receive the pluggable modules. The cage member has side walls along the sides of the upper and lower ports and a separator member extending between the side walls between the upper and lower ports. The separator member has an upper plate and a lower plate with a channel therebetween. An RF absorber is positioned within the channel that reduces an amount of EMI emitted from the channel.
US08277251B2 Electrical connector assembly with improved PCB engaging with a case
An electrical connector assembly (100) includes a case (1) defining a chamber therein; a connector (2) received in the chamber, the connector having a metallic shell (22); a printed circuit board (23) enclosed in the case, the printed circuit board having main portion and side portion laterally projecting from the main portion, the side portion having a conductive layer (230) on a top surface thereof, and a hole (231) defined in the side portion through the conductive layer, the hole further aligning with a through hole defined in the case; and the metallic shell of the connector soldered to the main portion of the printed circuit board.
US08277250B2 Wire harness and method of manufacturing the same
A wire harness includes a plurality of cables arranged in parallel, and a connector including a housing to which end portions of the plurality of cables are connected. Air-tightness between an air-tight block and the cables is maintained by inserting a melting member into cable insertion holes through a first insertion part, vibrating the melting member and pressing the melting member against a first press receiving part formed at an inner wall surface of the cable insertion holes such that a front end portion of the melting member in contact with the first press receiving part is melted into a melt resin to allow the melt resin to be poured into a gap between the cables and the air-tight block and a periphery of the cables to be covered with the melt resin.
US08277247B2 Shielded grip ring for coaxial connector
A grip ring for a coaxial connector couples with a coaxial cable with a solid outer conductor. The c-shaped ring is provided with a gap between a first end and a second end. A shield portion extends from the first end and a slot portion dimensioned to receive the shield portion provided in the second end. The shield portion keys with the slot portion as a diameter of the grip ring is reduced. An inner diameter of the grip ring is provided with a grip surface. Further, the grip ring may be provided with a flange edge at the cable end projecting from the outer diameter.
US08277245B2 Methods and systems for forming discrete wire ribbon cables
Methods and systems for forming discrete wire ribbon cables for use in electronic networks are provided. In some embodiments, the organizer may include an upper bracket and a lower bracket. The lower bracket may be configured to mate with the upper bracket. The upper bracket and the lower bracket may combine to define a plurality of holes. The plurality of holes may be sized to at least partially enclose a set of discrete conductors. Each of the set of discrete conductors may be individually insulated.
US08277244B2 Electrical connecting element and window pane provided with such an element
Electrical connecting element (2) that is designed to be welded or soldered onto an electrically conductive component (11) of a window pane, comprising an electrically conductive body (20), of which one section is designed to be welded or soldered onto the component (11) for its electrical connection, and of which another if section is designed to be connected in the direction of the outer side of the window pane, characterized in that the body comprises an electrically conductive foil (21) with a thickness between 1 and 500 μm and intermediate means (5, 6) that serve as shock-absorbing means between the stiff section of the body of the connecting element and the window pane.
US08277243B1 Connector position assurance device
A connector assembly is provided, and includes a first connector, a second connector, and a CPA device. The first connector has a stopper feature, a first end and a second end that generally opposes the first end. The stopper feature has a recess provided therein and a stopper surface. The second connector is received by the first connector. The second connector includes a shroud that slides over the first end of the first connector in a first direction. The CPA device is slidingly engaged with the second end of the first connector in a second direction that is generally perpendicular to the first direction. The CPA device has a flexible arm that is selectively deformable. In a pre-stage position, the flexible arm abuts against the stopper surface to restrict relative movement of the CPA device in the second direction.
US08277242B1 Connector retaining device having clamping plates sandwiching each other
A connector retaining device includes a first retaining frame and a similar second retaining frame. The first retaining frame includes two parallel first clamping plates, a first front opening at a front side thereof between the first clamping plates, a first rear plate at a rear side, a first side plate at one lateral side, and a first side opening at another lateral side. The first rear plate defines a first slot exposed at said another lateral side. The first clamping plates are configured for sandwiching a first connector. The first front opening is configured for allowing insertion of a second connector into the first retaining frame to engage with the first connector. The first side opening is configured for allowing insertion of the first connector into the first retaining frame. And the first slot is configured for allowing the first cable to extend and slide therethrough.
US08277235B2 Socket and motherboard with the same
A socket for selectively mounting on a board includes a housing and a latch. The housing includes a first side plate and a second side plate parallel to the first side plate. The first and second side plates define an elongated slot therebetween for reception of the board. The latch includes an axle, a body and a fastening portion. The axle is pivotably coupled to the housing at one end of the slot. The body has one end joined to the axle and the other end to the fastening portion. The fastening portion is constructed for engagement with the board. In addition, the lateral width of the body of the latch in the direction along the width of the first side plate is smaller than that of the axle in the same direction.
US08277233B2 Electrical outlet with changeable sockets
An electrical outlet includes a housing and a prong fitting member detachably connected to the housing. The housing includes two end surfaces and side surfaces between the two end surfaces. Each side surface defines a two-opening or three-opening socket for inserting a plug.
US08277227B2 Feedthrough for electrical connectors
A method (10) of forming an electrically conducting feedthrough. The method (10) comprises a first step (11) of forming an electrically conductive structure (21) comprising a sacrificial component and a non-sacrificial component. At least a portion of the non-sacrificial component can then be coated with a relatively electrically insulating material (35) prior to removal of at least a portion of the sacrificial component from the electrically conductive structure. The structure of the feedthrough provides electrical connection through the wall of a housing of an implantable component while preventing unwanted transfer of materials between the interior of the component and the surrounding environment.
US08277225B2 Kit for teaching the composition of blood
A kit for fabricating various visual models is used to teach students about blood, blood pathology, and the quantitative concepts associated with blood pathology. The kit includes various sized containers that hold colored beads that resemble red blood cells and the various types of white blood cells.
US08277222B2 Method and device for diagnosing and applying treatment for the emotional, physical, and cognitive development of a child for a multicultural society
The present invention relates to a method and device for diagnosing and applying treatment for the emotional, physical, spiritual, and cognitive development of a child by presenting illustrations having social and emotional attributes so the emotional, physical, spiritual, and cognitive levels of the child can be further developed in our multicultural society. This is a pyramid with hand/finger puppets, emotional faces, intellectual, educational and physical attributes.
US08277221B2 Talking plush novelty toy and interactive story book for teaching a reader desired behavioral patterns to protect oneself from sexual predators
A portable talking toy having an audio signal producer is provided with an educational book, which contains indiciums noted on at least one of the pages that are the same words or phrases uttered by the talking toy. The book has a plurality of numbered pages containing parts of a story. The story is used to teaching desired behavioral and psychological patterns that will aid the reader in learning how to self protect from sexual predators. The talking toy is provided with a pressure switch in the form of a button attached externally to the toy causing a sound to be emitted from the electronic voice box stored inside the toy. It will may have memory capable of storing and emitting words and sounds/words associated with indiciums noted in the story book and a microphone device for providing audible signals that enable sound, including music stored with each specific sound as background. The specific words communicate messages related to desired behavioral patterns. The books will contain multiple illustrations and indicium prompts indicating when the reader should press the button on the toy to hear the word or sound. Interaction between the characters in said book is purposed to encourage self-awareness in a reader encouraging him/her to pull cord or press the button on the toy thereby reinforcing the learning of the desired behavioral patterns.
US08277217B2 Dental instrument for cutting soft tissue
Disclosed is a dental instrument for cutting soft tissue. The dental instrument for cutting soft tissue according to the present invention includes: a main body having an inlet portion for inserting soft tissue to be cut into the main body; a cutter blade arranged in the main body such that at least a part of the cutter blade is exposed outwardly through the inlet portion; and a lid for covering the upper portion of the main body. The cutter blade includes a first cutter blade having a first cut depth, and a second cutter blade arranged in the vicinity of the first cutter blade, and which has a second cut depth shallower than the first cut depth. The dental instrument of the present invention makes it possible to cut the soft tissue in the deep part of a mouth in an easy and simple process, thereby improving the convenience of soft tissue implantation.
US08277216B2 Method and apparatus for preparing denture
A dental impression tray assembly includes an upper tray and a lower tray operable with the upper tray, and the lower tray includes a first piece configured to measure jaw relations of a patient's mouth and a pair of second pieces detachably attachable to the first piece. The first piece of the lower tray is inserted into the patient's mouth independently of the pair of second pieces of the lower tray to measure the jaw relations and to obtain a bite registration. After the first piece is connected to the pair of second pieces, the assembly allows a final gum impression of the patient's lower gum to be obtained.
US08277214B2 Device for intensifying a flame
A device for intensifying a flame, comprising an object intended to be placed in front of the burner head, at a distance from said burner head, so that it is placed at least partly inside a flame extending from the burner head, and furthermore, said object being arranged to glow, heated by said flame. An apparatus for applying the device, for heating a liquid or air, comprising a burner and a combustion chamber, wherein the apparatus comprises an object in the combustion chamber. In the method, the device is installed in front of the burner head, or in an apparatus for heating a liquid or air, comprising an opening for the burner head, and a combustion chamber.
US08277208B2 Split discharge vane pump and fluid metering system therefor
A split discharge vane pump is disclosed having a pump body that includes an interior pumping chamber having a central axis and defining a continuous peripheral cam surface, the cam surface including four quadrantal cam segments, wherein diametrically opposed cam segments have identical cam profiles, and each cam segment defines an inlet arc, a discharge arc and two seal arcs. A rotor is mounted for axial rotation within the pumping chamber and a plurality of circumferentially spaced apart radially extending vanes are mounted for radial movement within the rotor, wherein the plurality of vanes define an equal number of circumferentially spaced apart buckets which extend between the rotor and the cam surface of the pumping chamber for carrying pressurized fluid.
US08277206B2 Device and method for maintaining a static seal of a high pressure pump
A pressure enclosure includes a first component having an opening, a second component coupled to the first component in a position over the opening, a third component positioned between the first and second components and covering the opening, and a load chamber defined by a space between the second and third components and configured such that pressure in the load chamber biases the third component against the first component to seal the opening. The pressure enclosure may be a cylinder of a pump for pressurizing fluid or gas, with the first component a cylinder body, the second component an end cap and the third component a valve body, with the load chamber biasing the valve body against the cylinder body.
US08277205B2 Active electric accumulator
The present invention provides an active, electrically powered hydraulic fluid accumulator. The accumulator includes an electric motor having its output coupled to a mechanical rotation to linear translation transducer such as a lead screw, ball spline or similar device. The output of the mechanical transducer is coupled to a piston disposed within an accumulator cylinder. The accumulator cylinder preferably communicates with a pair of inlet and outlet check valves disposed in hydraulic supply and feed lines from the system pump or sump and to the system, respectively.
US08277204B2 Reciprocating motor and a reciprocating compressor having the same
A reciprocating motor and a reciprocating compressor having the same are provided. One side of each of outer and inner cores forming a stator are connected to each other, to prevent a magnetic flux generated by the coil and a magnet from leaking out of the stator. Hence, it is possible to fabricate components of the reciprocating compressor employing such a reciprocating motor by using a relatively low-cost magnetic substance, resulting in a decrease in fabricating costs of the compressor. Also, a length of the magnet may be reduced, which results in a reduction of the cost for the magnet, thereby decreasing fabricating costs of the reciprocating motor and the reciprocating compressor employing the reciprocating motor.
US08277202B2 Multicylindrical rotary compressor
There is disclosed a multicylindrical rotary compressor capable of improving an operation efficiency during a small-capacity operation, the compressor comprises a controller as a control unit which adjusts a rotation number of an electromotive element as a driving element and which controls an operation of a power saving mechanism, and the controller operates the power saving mechanism to connect a high-pressure chamber side of a first cylinder to a low-pressure chamber side of a second cylinder during the small-capacity operation of a refrigerant circuit constituted in a rotary compressor (the multicylindrical rotary compressor).
US08277198B2 Fan motor control systems
A control system for a fan includes a control housing that is external to a fan housing for the fan. At least one fan control module is within the control housing and communicates remotely with terminals within the fan housing via at least one wire. The at least one fan control module includes a detection module. The detection module detects induced voltages in at least one of a plurality of stator coils within the fan housing via the at least one wire without receiving signals from a sensor in the fan housing.
US08277197B2 Installation for high pressure compression with several stages
A multi-stage compression installation is formed of a main pipe (2) emerging in a baffle plate (3), where at least two compressors (4, 5) are mounted in series each having its own drive member (9, 10). The installation is equipped with a system for determining the pressure at the output of the main pipe (2), the installation being connected to a control box (8). Typically, the control box (8) is connected to at least two of the drive members (9, 10) of the compressors (4, 5) and ensures monitoring of the compressors such that the latter rotate jointly whether charged or uncharged. Thus, the compressors (4, 5) are jointly charged based on the pressure prevailing in the baffle plate (3), such that the charging of the compressor representing the overpressure stage, the compressor(s) of the lower compression stages are automatically and jointly charged.
US08277195B2 Coated turbine component and method of coating a turbine component
Turbine components with different types of coatings on different parts thereof are described. The coatings are chosen such that they are especially adapted to the thermal and corrosive conditions being present on the parts of the component during use. A method to coat a turbine component is also described.
US08277194B2 Component to be arranged in the flow channel of a turbomachine and spraying method for producing the coating
The invention relates to a component for arrangement in the duct of a turbine engine. The component is provided with a coating, which has a surface structure with scales which overlap each other in the direction of flow of the turbine engine. The invention also relates to a spraying method for generating a coating on a component.
US08277188B2 Turbomachine rotor disk
A turbomachine rotor disk including inter-blade platforms fixed to ribs delimited by cavities in which blade roots are retained, and protective liners mounted between the flanks of the cavities of the disk and the blade roots is disclosed. The protective liners have a C-shaped cross section so that they can be fitted translationally and retained radially on the ribs of the disk and constitute a locking device which locks the platforms on the ribs of the disk.
US08277187B2 Radial compressor rotor
A radial compressor rotor is provided for stabilizing the flow behavior of a delivery gas, consisting of a wheel disc and blades arranged uniformly in the circumferential direction, wherein the generatrix of the surface of the blades is designed as a curved line at least in a curved section, such that the surface is curved in two directions in this section.
US08277186B2 Turbine blade assembly and steam turbine
A turbine blade 10a which is a stop blade is provided with a cutout portion 50 which is formed in one circumferential side surface 22a of a shank portion 22 at the center in the axial direction of a turbine rotor 100, a cutout portion 60 which is formed in one circumferential side surface 22a of the shank portion 22 from one end portion 22b to the cutout portion 50 in the axial direction of the turbine rotor 100, and a through passage 70 which is formed to pass from the cutout portion 50 to an effective blade part and in which a moving member 170, which moves a stopper member 160 to the effective blade part in the cutout portion 50, is inserted.
US08277184B2 Tilt adjustment system
A wind energy system is provided with said wind energy system including a hub pivotable about a rotation axis, a first bearing connected to said hub, a tapered adapter, a second bearing connected to said first bearing by said adapter, wherein said first and second bearings and said adapter are arranged such that the tilt angle of said rotation axis of said hub is adjustable. Further, a tilt adjustment system for a wind energy system and a method for operating a wind energy system is provided.
US08277183B2 Systems and methods for monitoring wind turbine operation
A method is provided for monitoring a wind turbine using a combined supervisory command and data acquisition (SCADA) and video monitoring system. The method includes receiving video data from at least one video camera, wherein the video data is related to operating conditions of the wind turbine. The method also includes storing the video data in a memory, and receiving a command from a remote monitoring server relating to at least a portion of the video data, wherein the portion of the video data is associated with at least one SCADA data point. The method also includes retrieving the portion of the video data from the memory, and transmitting the portion of the video data to the remote monitoring server for presentation to a user.
US08277179B2 Turbine or compressor stage for a turbomachine
A turbine or compressor stage for a turbomachine is disclosed. The stage includes a blade wheel surrounded by a sectorized ring carried by a casing. Each ring sector includes a circumferential rim that is clamped radially a casing rail by two clamps of C-shaped section that are engaged on the circumferential end portions of the rim of the ring sector and on the corresponding portions of the casing rail.
US08277172B2 Apparatus for turbine engine cooling air management
An exemplary embodiment of the invention is directed to a turbine engine having a first, rotatable turbine rotor assembly, a second, stationary nozzle assembly disposed adjacent thereto and a wheel space which is defined between the first, rotatable turbine rotor assembly and the second, stationary nozzle assembly. The wheel space is operable to receive cooling air therein and includes a sealing feature located on the first rotatable turbine rotor assembly that extends axially into the wheel space to terminate adjacent to a sealing land positioned on the second, stationary nozzle assembly. The sealing feature and the sealing land operate to control the release of cooling air from within the wheel space and the sealing land is constructed of shape memory alloy.
US08277170B2 Cooling circuit for use in turbine bucket cooling
A system and a method to supply a coolant to a turbine bucket of a turbine. The system includes an extraction system configured to extract air from a main compressor airflow, a supply circuit, at least a part of which is disposed at an exterior of the gas turbine, coupled to the extraction system and configured to transport the extracted air, as an ingredient of the coolant, from the extraction system to a coolant insertion region, and a cooling system, disposed proximate to the coolant insertion region of the gas turbine and coupled to the supply circuit at a position on-board the gas turbine, the cooling system being configured to supply the turbine bucket with the coolant, including the extracted air.
US08277169B2 Turbine rotor cooling flow system
Disclosed herein is an apparatus comprising a disk coverplate for a turbine rotor, the disk coverplate comprising a plurality of cooling holes, wherein the distance between the centers of any two adjacent cooling holes is greater than twice the average diameter of the two adjacent cooling holes. A method to control turbine cooling air flow is also disclosed.
US08277165B2 Transfer mechanism with multiple wafer handling capability
An integrated robotic mechanism is disclosed for improving transport equipment, integrating an object movement with other functionalities such as alignment or identification. The disclosed integrated robot assembly can comprise a multiple end effector for moving a plurality of workpieces, a single end effector for moving a single workpiece, a rotation chuck incorporated on the robot body to provide alignment capability, and an optional identification subsystem for identify the object during transport. The present invention robot assembly can be used in a sorter or stocker equipment, in processing equipment, and a transfer system.
US08277163B2 Substrate transfer apparatus, substrate process system, and substrate transfer method
A substrate transfer apparatus includes forks that are vertically spaced apart from each other with a predetermined distance. When the forks take out the substrates from the first substrate containing part, each of the forks lifts the substrate and supports the same by moving upward from a pre-loading position located below the substrate to be taken out by a predetermined unloading stroke amount. A value of the predetermined distance is set to be equal to the sum of the distance between the substrates contained in the first substrate containing part and the unloading stroke amount.
US08277160B1 Protective wire fastening apparatus
An apparatus for protecting and fastening a wire to a mounting object includes a molded unibody having a first section connected to a second section, wherein the first section includes a surface that operates to receive a fastener, such as a staple, therethrough to secure the wire in place against the mounting object, and the second section protrudes from the surface of the first section and extends away from the surface of the first section for a user to safely hold the first section in place as the user mounts the apparatus and the wire to the mounting object.
US08277159B2 Manx fastener
A splayable fastening device comprises a fastener engagable element having a screw-threaded element, at least one flexibly springable arm member which is at least in part wrapable about a screw-threaded axis of the screw-threaded element, and a retainer for retaining the said flexibly springable arm member in its wrapped or coiled condition. The retainer is movable relative to the flexibly springable arm member whereby the flexibly springable arm member is unfurlable in a clockwise or anticlockwise direction. A method of fastening to a hollow wall using such a splayable fastening device is also provided.
US08277155B2 Railroad car coil restraint system
A transverse railroad coil car coil restraint apparatus or system which includes a plurality of coil restraints attachable to each trough in a transverse railroad coil car to reduce the sideways shifting of coils positioned in the troughs. In certain embodiments, the coil restraints are attached in each trough and extend across the transverse coil car. In other embodiments, the coil restraints are attached in each trough along the length of the trough. In certain embodiments, when a coil is positioned in the trough, the coil compresses certain of the coil restraints and does not compress other of the coil restraints which prevents the sideways shifting of the coil during movement of the transverse coil car. In other embodiments, when a coil is positioned in the trough, the coil compresses certain of the compression members and does not compress other of the compression members which prevents the sideways shifting of the coil during movement of the transverse coil car.
US08277152B2 End mill
An end mill having a gash formed in a top portion of a flute. In a cross-section perpendicular to an intersecting ridgeline between an end cutting edge rake face and a gash bottom face of the gash, the gash bottom face and the end cutting edge rake face, and the gash bottom face and the gash wall face are respectively connected together by first and second connecting faces. The connecting faces have a form which either is a concave curve or a substantially concave curve formed with straight lines. A radius of curvature of the concave curve or the radius of a circle inscribed within straight lines forming the substantially concave curve about the front connecting face is larger than a radius of curvature of the concave curve or the radius of a circle inscribed within the straight lines forming the substantially concave curve about the second connecting face.
US08277148B2 Re-tensionable cable bolt apparatus and related method
A re-tensionable cable bolt and related methods are provided. In one aspect of the invention, the bolt includes a sleeve for connecting or securing to a cable. The sleeve includes a lower end having a bore adapted for receiving a threaded shank for associating with a tension nut. A plurality of facets along a peripheral portion of the sleeve create corners that prevent the cable from rotating within the borehole during installation. The sleeve may be secured to the cable using resin, which forms another aspect of the invention.
US08277146B2 Wave power plant
An improved wave energy collecting apparatus comprising a frame (1) including at least one hinged (2) vertically tilting or rotating surface (3), such as a barrier in the form of a panel or a sail, for collecting energy from passing wave pressure fronts via a tilting or rotating motion within the frame (1), wherein the hinge (2) is positioned below the surface of the fluid at the trough of the passing waves, said barrier (3) being connected to a device capable of transforming the tilting or rotating motion into different types of energy, wherein the apparatus is located at a depth such that the tilting or rotating barrier (3) breaks the surface of passing waves at the crest of the waves. Such an apparatus may also include vertically positioned side walls (4) for directing the pressure fronts from passing waves towards the tilting barrier (3).
US08277143B2 Surface mount vehicle anti-ram security systems
Anti-ram systems according to embodiments of the invention comprise at least one bollard section comprising a base of limited height and a plurality of spaced bollards extending upwardly from the base. An anti-ram system according to embodiments of the invention may be erected or installed on a paved surface such as asphalt, concrete, paver stones, etc., or on an unpaved surface such as soil, and need not be partially of fully buried, and yet can qualify for Department of State crash ratings previously assigned to buried bollard systems. Disclosed anti-ram system also comprise a plurality of bollard sections and one or more connectors for interconnecting two or more of the bollard sections, and may also include an anchor or anchor system engaging at least each end of a bollard section not connected to another bollard section. The bollard sections may be filled with ballast and high friction structure may be attached to the bottom of the bollard sections to resist sliding after impact.
US08277142B2 Shaft connection structure
A tightened shaft portion 51a of a shaft 51 and a tightened portion 42b of a lower joint yoke 42 are coupled with each other such that a required torque can be transmitted therebetween by inserting the tightened shaft portion 51a of the shaft 51 into a shaft insertion hole 42b2 of the lower joint yoke (a coupling member) 42, and inserting a bolt 44 into a bolt insertion aperture 42b3 of the lower joint yoke 42 and a bolt engagement groove 51a1 of the shaft 51 and tightening the bolt in the condition (the regular position condition) that the bolt engagement groove 51a1 of the shaft 51 and the bolt insertion aperture 42b3 of the lower joint yoke 42 are axially aligned with each other. An insertion restriction portion 51b having a diameter smaller than that of the tightened shaft portion 51a is provided at the tip end of the tightened shaft portion 51a of the shaft 51 for restricting the insertion of the bolt 44 through the bolt insertion aperture 42b3 of the lower joint yoke 42 in the condition (the non-regular position condition) that the insertion restriction portion 51b axially overlaps the bolt insertion aperture 42b3 of the lower joint yoke 42 when the tightened shaft portion 51a is inserted into the shaft insertion hole 42b2 of the lower joint yoke 42, and the insertion restriction portion 51b can be rotated relative to the shaft 51 by a set torque smaller than the required torque.
US08277140B2 Loose-leaf binder
A binder for releasably retaining loose-leaves. The binder has a front cover that lies flatly beneath its back cover when the binder is open 360 degrees. The rings of the binder can rotate around an edge of the flatly-folded cover to enable loose-leaves to lie flat above and below the cover. The binder also has a skeleton with a minimal cross-section spine which may be partially or completely embedded in a cover and rotates in relation to parallel front and back covers when the binder is open 360 degrees. The front cover, middle cover and back cover are connected in a way so that they do not interfere with the rotation of the rings. Mechanisms to open and close the rings of the skeleton to allow addition or removal of loose-leafs, and ring shapes to optimize or stabilize the capacity of the binder during operation are also disclosed.
US08277133B2 Focal plane shutter for cameras
A focal plane shutter for cameras includes: a shutter blade assembly; an electromagnet assembly; driving means that includes a mounting member mounted with an iron scrap member that cooperates with an iron core member of the electromagnet assembly; and a setting member that operates the driving means to a set position. The iron scrap member includes a shaft fitted in a mounting hole of the mounting member, an iron scrap portion provided at one end of the shaft and brought into contact with the iron core member, and a removal preventing flange provided at the other end of the shaft, a collar member is fitted to the shaft between the mounting hole and the flange, an edge of the mounting hole is formed to have an arcuate surface protruding toward the collar member, and the collar member is formed to have, on the edge side, an arcuate surface protruding toward the flange and substantially perpendicular to the arcuate surface.
US08277126B2 Fluid dynamic bearing device
A protrusion (7b3) directed axially downwards is provided at a bottom portion (7b) of a housing (7), and an outer peripheral surface (7b31) of the protrusion (7b3) is fixed to an inner peripheral surface (6a) of a bracket (6). When a thrust load is applied to the bottom portion (7b) of the housing (7), a part of the load is supported by the bracket (6) via the protrusion (7b3). Thus, a strength of a boundary portion (P) between a side portion (7a) and the bottom portion (7b) of the housing (7) increases, making it possible to prevent rupture of the boundary portion (P) due to an excessive thrust load. On the other hand, a wall thickness of the bottom portion (7b) can be made invariable, so it is possible to suppress deformation through molding shrinkage of a thrust bearing surface formed on an inner end surface (7b1) of the bottom portion (7b).
US08277125B2 Bearing apparatus, spindle motor, and disk drive apparatus
In a bearing apparatus, a first cup portion defining a portion of a stationary portion of a bearing apparatus includes a circular plate portion and a cylindrical portion projecting downward from an outer edge portion of the circular plate portion. A rotating portion of the bearing apparatus includes an annular recessed portion arranged to accommodate at least a lower end portion of the cylindrical portion. Accordingly, it is possible to limit the axial dimension of the bearing apparatus while also enabling both a radial dynamic pressure groove array and a pumping groove array to have a sufficient axial dimension. Additionally, one end of a through hole defined in the rotating portion is arranged to open into the annular recessed portion, so that any air bubbles introduced into a lubricating oil by the pumping groove array can be efficiently caused to flow downward through the through hole and out of the bearing apparatus.
US08277123B2 Fluid bearing structure and method of forming bearing concaves in fluid bearing structure
A fluid bearing structure with uniform depths of bearing concaves and a method of forming the bearing concaves in the fluid bearing structure. Pipe parts are inserted into through holes formed in the bearing base to form fluid spout holes for spouting fluid between confronting bearing surfaces. Bearing concaves are formed around the fluid spout holes. The bearing base and the pipe parts are made of different materials. A coating layer is formed on the bearing base and the pipe parts by an anodic oxidation process. Thickness of the coating layer on the bearing base is different from thickness of the coating layer on the pipe parts since the base member and the pipe members are made of different materials. The material on which a coating layer grows quickly is selected for the bearing base and the material on which a coating layer grows slowly is selected for the pipe parts.
US08277121B2 Bag construction with flat bottom having removable layer
A bag construction filled with dispersible material. The bag construction has first and second panel sections, first and second side gusset sections and a bottom gusset panel section. The various panel sections are fastened together to form a generally rectangle shape with a flat bottom. The bottom gusset panel section has one or more distribution apertures in it. A removable panel layer is provided for covering the one or more apertures. When the removable panel layer is removed, the bag can be held so that the dispersible material disperses through the apertures as appropriate.
US08277119B2 Fiber optic temperature sensor
A temperature sensor, capable of operating in electromagnetic and/or electric environments such as electrical generators, motors and transformers and/or in environments where vibratory conditions are frequent or continuous, contains at least one light emitting optic fiber and one light receiving optic fiber and an electrically non-conductive dilatable object which variably occults the emitted light as the object's temperature varies. The light receiving optic fiber transmits light intensity and light intensity changes to an electronic device that may include a photometer and light-to-temperature computing equipment.
US08277116B2 Fluidic mixer with controllable mixing
In one embodiment of the disclosure, a fluid mixing device comprises a flow duct, with a wall having an inner surface defining a fluid flow path for a primary flow, and at least one deployable and retractable projection. The projection is adapted to controllably generate at least one secondary flow adjacent the inner surface. In other embodiments, methods are provided of controllably mixing at least one fluid within a fluid mixing device.
US08277113B2 Adhesive dispenser apparatus having a mixing device with a corrugated conveying plate
A dispenser apparatus for dispensing an adhesive containing at least two components includes a mixing device and a header. The mixing device comprises a conveying plate having first and second grooved surfaces each overlaid by a respective cover plate. The conveying plate and opposed cover plates cooperate to define a plurality of separated channels extending through the mixing device. The discharge ends of the channels are interdigitated. First and a second distribution manifolds are defined within the mixing device. A supply port adapted to receive one adhesive component extends through a respective cover plate into fluid communication with one of the distribution manifolds.
US08277101B2 LED headlight cooling system and LED headlight thermal conducting device
An LED headlight cooling system includes a vehicle air conditioner, a thermal conducting device and an LED headlight. The vehicle air conditioner has a cooling device. The thermal conducting device is thermally connected to the cooling device of the vehicle air conditioner. The LED headlight is thermally connected to the thermal conducting device.
US08277099B2 Vehicle lighting system
A vehicle lighting system according to the present invention is provided, and includes: a pivot portion for optical axis adjustment; an optical axis adjustment mechanism mounting portion for vertical direction; and an optical axis adjustment mounting portion for horizontal direction, which are integrally provided at a heat sink member having a semiconductor-type light source mounted thereon. As a result, the vehicle lighting system becomes capable of efficiently radiating a heat generated in the semiconductor-type light source by means of the pivot portion for optical axis adjustment and the optical axis adjustment mechanism mounting portions for vertical and horizontal directions, which are integrally provided at the heat sink member.
US08277091B2 Abuse-resistant light fixture
An abuse-resistant light fixture housing having a mounting plate with mounting brackets, a frame having an opening for a-non opaque cover, and a plurality of fasteners affixing the mounting bracket to the frame is provided. When the mounting plate and frame are assembled together the frame is suspended apart from the mounting bracket such that impacts against the frame are absorbed by the suspension elements allowing the frame and light elements to survive generally undamaged. Elements of the fixture are made so as to resist damage while providing illumination.
US08277083B2 Discharge tube, lighting device, display device and television receiver
A discharge tube 17 of the present invention includes a glass tube 60 and ferrules 70 disposed around ends of the glass tube 60. Outer leads 61 for receiving power from an external power source project from ends of the glass tube 60. Each ferrule 70 includes a body 71 that is fitted onto the glass tube 60 and an insertion portion 73 that is disposed near the end of the body 71 and into which the outer lead 61 is inserted. The outer lead 61 includes a loop portion 62 at the end thereof. The outer lead 61 is electrically connected with the ferrule 70 when the loop portion 62 is inserted in the insertion portion 73.
US08277075B2 Illumination device using solar energy
An illumination device includes a reflection disk, a positioning frame, a solar cell module, an illumination member and a driving device. The positioning frame is located at the focus of the curved reflection surface of the reflection disk. The solar cell module and the illumination member are respectively connected to the front and back of the positioning frame. The driving device is used to drive the positioning frame to rotate relative to the reflection disk. When the solar cell faces the curved reflection surface, the solar cell absorbs the reflected sun light to generate electric power. When the illumination member faces the curved reflection surface, light emitted from the illumination member is reflected by the curved reflection surface.
US08277074B2 Portable light apparatus and method of attachment
An organic light emitting diode system is sufficiently thin and poser efficient to permit its attachment to different configurations such as pocketbooks, brief bags, suitcases and the like. At least one side of the OLED material can have an attachment mechanism to facilitate attachment to a surface in the area to be lighted. The system may include a portable power source that provides electrical power to actuate the OLED material, causing it to generate light. A switch connected to the battery can control power to the OLED material to switch the light on and off. The switch can be manually operated or automatic. The low power consumption of embodiments of the OLED apparatus also provides for unique applications and uses.
US08277072B2 Multi-function solar-powered lighting system
A solar-powered lighting system includes a substrate, wherein at least one solar chip is disposed on one lateral side of the substrate, and at least one light source is disposed on one lateral side of the substrate. Solar light enters the substrate and propagates therein. Solar light energy is collected by the at least one solar chip which transforms the solar light energy into electrical power for the at least one light source to emit light to the substrate, before propagating therein and leaving the substrate.
US08277069B2 Entertaining and promotional head gear
A head gear that provides entertainment and effective advertising with a main body and an attached visor body having an upper portion and a lower portion pivotably connected to each other. The main body fits over or around a wearer's head. The upper portion of the visor body has an area for receiving markings, and along the perimeter of the area is a plurality of light source for illuminating the entire area. A user can make different markings in the area. In an open position, the upper portion is at a substantially right angle relative to the lower portion such that the area with the markings is displayed to a viewer in a forward position. In a closed position, the area is concealed and protected by the lower portion. Use of ultraviolet light emitting diodes and phosphorescent or fluorescent markings provide enhanced entertainment and advertisement value.
US08277065B2 Illumination system for cavities
A system to light a cavity 19 in an appliance. A source or light emitter 27 is mounted on a circuit board 32, so that the light emanating from said source or light emitter 27, is concentrated into a light beam using an optical collimator system 28 or in some cases a Fresnel arrangement; wherein the foregoing elements may be found outside a door 14, which allow access into the cavity; thus the light beam exiting the optical collimator 27 or Fresnel arrangement travels a distance though air between the optical collimator system 27 or Fresnel arrangement and the upper face of the light guide 29 which is placed on the door 14, the light guide 29 transports the luminous flux towards a notch which diverts said luminous flux directing into the cavity's 19 interior.
US08277058B2 Optical structures including polyurea
Optical structures and sheeting that include polyurea and method for forming same are proposed in accordance with aspects of the present invention. One and two-component layers can be used to form the optical structures. The optical structures can include microstructures formed from polyurea. The sheeting can include at least one of cube-corner prisms, open-faced cube-corner prisms, linear prisms, lenticular lenses, moth-eye structures, lenses, Fresnel lens arrays, lenses, and fish-eye lens arrays.
US08277057B2 Projection display apparatus
A first detection unit and a second detection unit detect the light that is incident from the direction where a screen is to be located. A controller determines whether the screen is located at a recommended position based on output signals from the first detection unit and the second detection unit. When the screen is located at the recommended position, the controller controls the projection display apparatus so as to be in the state where a significant image can be projected. The controller may determine whether the screen is located at the recommended position and in a normal state based on the output signals. When the screen is located at the recommended position and in a normal state, the controller may control the projection display apparatus so as to be in the state where a significant image can be projected.
US08277055B2 Multiple view display system using a single projector and method of operating the same
A system and method to display a plurality of different images at multiple distinct locations using a single image projector and an image propagation control means to control a propagation pathway from the projector to a display at each location.
US08277045B2 Tri-colored lens for spectacles
A specially tinted lens, a tri-colored lens for spectacles and sunglasses for use in flying airplanes. A far field of vision has a first tinting, such as green, to reduce the light from a sunlit sky, over sunlit cloud tops, or in clouds, which enables an aircraft pilot to easily see out of the cockpit into highly illuminated environments. An intermediate field of vision has a second tinting, such as yellow, to enable the pilot to easily see a dimly illuminated instrument panel as compared to outside the aircraft. A near field of vision has a third tinting, such as neutral in color, to enable said pilot to easily view maps and other information.
US08277044B2 Mobile telephonehaving internal inkjet printhead arrangement and an optical sensing arrangement
A mobile telephone includes an optical sensing arrangement enabling the telephone to decode tags of coded data printed on media fed through the telephone via internal and external media pathway defined by a body of the telephone; a beam splitter deflecting incoming light onto an image sensor of the telephone; a first infrared LED directing light onto media present in the external pathway; a filter and lens arrangement receiving and directing light reflected from the external media onto the beam splitter; a second infrared LED directing light onto media present in the internal pathway; and a mirror arrangement directing light reflected from the internal media into the beam splitter. The coded data contains printing instructions for the printhead, and the filter and lens arrangement includes an infrared filter for removing non-infrared ambient light, whereby a signal to noise ratio of the reflected light is improved.
US08277043B2 Handy printer and mobile phone provided with the same
A handy printer and a mobile phone based on the use of the same are provided, wherein the printing can be performed on recording paper sheets having various sizes. The handy printer comprises a cover member which is movable between an exposure position at which an ink discharge surface of an ink discharge head is exposable to the outside and a cover position at which the discharge surface is hidden from the outside. When the cover member is positioned at the cover position, the recording is permitted on a recording paper sheet accommodated in a recording paper-accommodating mechanism. When the cover member is positioned at the exposure position, the recording is permitted on a recording medium disposed outside a handy-printer body casing.
US08277041B2 Ink-jet recording apparatus
An ink-jet recording apparatus, including: a first recording head and a second recording head each having a plurality of ejection openings from which ink is ejected; a conveying mechanism which defines a conveyance path through which a recording medium is conveyed so as to pass a first position at which the recording medium is opposed to the ejection openings of the first recording head and a second position at which the recording medium is opposed to the ejection openings of the second recording head; and a bypass conveying mechanism which defines a bypass path that is connected to the conveyance path at a position thereof between the first position and the second position, for permitting the recording medium to be conveyed so as to bypass the second position.
US08277039B2 Inkjet printer and a paper transportation method
An inkjet printer prevents the paper from lifting away from the platen when the suction action of the platen is stopped, and thereby prevents paper jams and other printing problems. The printer 1 conveys the printing paper 12a while holding the paper 12a to the surface of the platen 19 by a suction mechanism 50. After the automatic paper cutting operation is completed, the leading end part 12b of the printing paper 12a is retracted from the cutting position B to the printing start position A on the platen 19, and the printer 1 waits for the next print job with the printing paper 12a held against the platen 19. When a power conservation mode or power off mode is entered, the control unit 61 of the printer 1 advances the leading end part 12b of the printing paper 12a from the printing start position A to the cutting position B so that the paper is held by the downstream-side paper feed roller 34 and pressure roller 35, and then stops the power supply to the suction mechanism 50 of the platen 19. The printing paper 12a can thus be prevented from rising away from the platen 19 while the vacuum action of the suction mechanism 50 is stopped.
US08277029B2 Printhead integrated circuit having low mass heater elements
A printhead integrated circuit includes: a plurality of nozzle chambers disposed on a substrate; a heater element positioned in each nozzle chamber; drive circuitry for supply power to each heater element; and a plurality of ink supply channels defined in the substrate for supplying fluid to the nozzle chambers. Each heater element consists of solid material having a mass of less than 10 nanograms. In use, the solid material is heated to cause formation of a gas bubble inside each nozzle chamber.
US08277023B2 Inkjet printhead and method of manufacturing the same
Disclosed are an inkjet printhead and a method of fabricating the same. The inkjet printhead can include a substrate; a chamber layer formed on the substrate and a nozzle layer formed on the chamber layer. The chamber layer defines one or more ink chambers in which ink to be ejected may be accommodated. The nozzle layer includes one or more nozzles through which the ink from the ink chambers are ejected. The nozzle layer may be formed of a cured product of a photosensitive dry film that includes an light absorption material.
US08277018B2 Tilt angle maintaining apparatus and recording apparatus
A first ratchet claw and a second ratchet claw are formed on a lock member which is provided in a reciprocating manner with respect to a guide member, wherein a plurality of first and second ratchet recesses for being fitted to the first and second ratchet claw and the first and second ratchet claw are provided on the guide member along a sliding direction of the guide member, and wherein when a lever member which is slidably provided on the guide member is in the unlocked position, the first and second ratchet recesses are continuously formed along a sliding direction of the guide member arranged in an relationship in which at least one of the first and second ratchet recess does not face the first ratchet claw in the case of the first ratchet recess or the second ratchet claw in the case of the second ratchet recess.