Document Document Title
US08247708B1 Cable seal apparatus and techniques for outside plant telecommunications housings
Signals entering outside plant (OSP) telecommunications enclosures typically do so through weather tight connectors, with one connector mounted to the enclosure and a mating connector connected to a cable bringing the signals to the OSP housing. Such connectors are expensive and require extensive effort to connect the wires of a cable bundle to the connectors. These problems are avoided by allowing cables pre-installed with a cable seal and pre-terminated to cable connectors to pass through an opening in the wall of an OSP housing and seal the cable bundle to the housing to prevent the ingress of environmental elements into the housing through the opening. This permits easier installation and retrofitting of electronic equipment contained within the housing.
US08247701B2 Electroconductive particle placement sheet and anisotropic electroconductive film
This invention provides an electroconductive particle placement sheet comprising electroconductive particles and an insulating resin sheet. The thickness of the insulating resin sheet is smaller than the average particle diameter of the electroconductive particles. Electroconductive particles are protruded from the reference plane (P1) on at least one side of the insulating resin sheet. The electroconductive particle in is part protruded from the reference plane (P1) is covered with a layer formed of the same resin as in the insulating resin sheet.
US08247692B2 Electronic device
An electronic device includes a housing, at least two latching members, an inner frame received in the housing, and at least two bonding films. The latching members are fixed to the inner frame by the bonding films, the housing defines at least two locking portions latched with the at least two latching members.
US08247686B2 Multi-layer N-type stack for cadmium telluride based thin film photovoltaic devices and methods of making
Thin film photovoltaic devices are provided that generally include a transparent conductive oxide layer on the glass, a multi-layer n-type stack on the transparent conductive oxide layer, and an absorber layer (e.g., a cadmium telluride layer) on the multi-layer n-type stack. The multi-layer n-type stack generally includes a first layer (e.g., a cadmium sulfide layer) and a second layer (e.g., a mixed phase layer). The multi-layer n-type stack can, in certain embodiments, include additional layers (e.g., a third layer, a fourth layer, etc.). Methods are also generally provided for manufacturing such thin film photovoltaic devices.
US08247683B2 Thin film interlayer in cadmium telluride thin film photovoltaic devices and methods of manufacturing the same
A cadmium telluride thin film photovoltaic device is provided having a thin film interlayer positioned between a cadmium sulfide layer and a cadmium telluride layer. The thin film interlayer can be an oxide thin film layer (e.g., an amorphous silica layer, a cadmium stannate layer, a zinc stannate layer, etc.) or a nitride film, and can act as a chemical barrier at the p-n junction to inhibit ion diffusion between the layers. The device can include a transparent conductive layer on a glass superstrate, a cadmium sulfide layer on the transparent conductive layer, a thin film interlayer on the cadmium sulfide layer, a cadmium telluride layer on the thin film interlayer, and a back contact on the cadmium telluride layer. Methods are also provided of manufacturing such devices.
US08247681B2 Solar cell connecting apparatus
The invention relates to a solar cell connecting apparatus, for example a solar cell connecting apparatus, for manufacturing solar cell strings from individual solar cells and electrically conductive strips, having a first module for joining solar cells and strips together; a second module which is connected to the first module for connection, for example, soldering of the strips to the solar cells; and a third module for transportation of the solar cells from the first module through the second module. The connecting apparatus is characterized in that the first module has an apparatus for placing a strip retaining element on to a solar cell with strips, in order to fix the strips on the solar cell, and the third module is adapted in order to also transport the retaining element together with the solar cell.
US08247680B2 Light energy conversion material
A light energy conversion material that includes a porous material including an electron donor in a skeleton thereof; and an electron acceptor disposed in at least one portion among a pore, the skeleton and the outer circumference of the porous material.
US08247679B2 Apparatus for generating electrical power from the waste heat of an internal combustion engine
An apparatus for generating electrical power from the waste heat generated by an internal combustion engine includes a first pipe wall through which a heated medium flows, a thermoelectric generator disposed exteriorly to the inner pipe wall, and a second pipe wall disposed exteriorly to the thermoelectric generator. The first pipe wall and the second pipe wall form at least a partially double-walled pipe. The first pipe wall saves as a high-temperature source. The second pipe wall serves as a low-temperature source.
US08247678B1 Membranophone tuning system having positionable magnets
A system for changing the acoustical characteristics of a musical membranophone having a vibrating membrane or a stringed musical instrument having a sound box includes an overlay including indicia dividing a surface of the vibrating membrane or sound box into discrete zones enabling a user to position magnetic members to obtain predictable effects based on experimentation or a guide such as a diagram illustrating the position of magnetic members on the overlay, a first rare earth magnetic member is adapted to be disposed on a first side of the membrane or sound box, a second rare earth magnetic member is disposed on an opposed side of the membrane or sound box such that the first and second magnetic members are magnetically engaged on opposed sides of the membrane or sound box wherein the mass of the first and second magnetic member is sufficient to change the acoustical characteristics of the instrument.
US08247674B2 Slide bar holder
A slide bar holder removably secures a slide bar to a stringed musical instrument. The slide bar holder includes an instrument attachment clip and a slide bar clip. The instrument attachment clip has an elongate central portion and a pair of opposing jaws disposed at opposite ends of the central portion which extend from the central portion in a first direction. The jaws of the instrument attachment clip are operable to removably receive the body portion of the musical instrument and thereby secure the slide bar holder to the musical instrument. The slide bar clip has a pair of opposing jaws that extend from the central portion of the instrument attachment clip in a second direction that is opposite the first direction. The jaws of the slide bar clip are spaced apart by a distance substantially equivalent to the diameter of the slide bar, such that the jaws of the slide bar clip are operable to removably receive and secure the slide bar in the slide bar holder.
US08247673B1 String tuning orbital with ergonomic features
A string tuning system useful for both acoustic and amplified instruments provides a nondestructive method and kit to replace existing thumb peg tuning controls with ergonomic orbital controls. Orbital controls are sometimes referred to as “orbs” and may comprise round tuning knobs that make string manipulation ergonomic. In one embodiment, a tuning assembly 800 comprises a headstock bolt 650, comprising a threaded shaft section 651 and nut section 652, with the headstock bolt 650 fitting into the housing 506 of the string attachment shaft 500. The main wall 103 of the orb contains a perpendicular orb void 105, the orb void 105 being sometimes used to accept an orb set screw 106. The orb 100 also comprises an interior center vertical void 104, the interior center vertical void 104 sometimes used to accept an orb collar 107. The orb collar 107 comprising a main pipe like body 114, a bottom edge 109, a top edge 110, an interior vertical void 111 and a perpendicular void 108.
US08247671B1 Inbred maize variety PH1380
A novel maize variety designated PH1380 and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1380 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PH1380 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PH1380 or a locus conversion of PH1380 with another maize variety.
US08247668B1 Maize variety hybrid X05A930
A novel maize variety designated X05A930 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X05A930 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X05A930 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X05A930, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X05A930. This invention further relates to methods for producing maize varieties derived from maize variety X05A930.
US08247663B1 Maize variety PHEKJ
A novel maize variety designated PHEKJ and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PHEKJ with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into PHEKJ through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. Hybrid maize seed, plant or plant part produced by crossing the variety PHEKJ or a trait conversion of PHEKJ with another maize variety. Inbred maize varieties derived from maize variety PHEKJ, methods for producing other inbred maize varieties derived from maize variety PHEKJ and the inbred maize varieties and their parts derived by the use of those methods.
US08247662B2 Tomato line FIR 128-1032
The invention provides seed and plants of tomato hybrid HNX12860544 and the parent lines thereof. The invention thus relates to the plants, seeds and tissue cultures of tomato hybrid HNX12860544 and the parent lines thereof, and to methods for producing a tomato plant produced by crossing such plants with themselves or with another tomato plant, such as a plant of another genotype. The invention further relates to seeds and plants produced by such crossing. The invention further relates to parts of such plants, including the fruit and gametes of such plants.
US08247661B2 Cotton variety FM 9150F
A novel cotton variety, designated as FM 9150F, is disclosed. The invention relates to seeds, plants, plant cells, plant tissue, harvested products and cotton lint as well as to hybrid cotton plants and seeds obtained by repeatedly crossing plants of variety FM 9150F with other plants. The invention also relates to plants and varieties produced by the method of essential derivation from plants of FM 9150F and to plants of FM 9150F reproduced by vegetative methods, including but not limited to tissue culture of regenerable cells or tissue from FM 9150F.
US08247660B1 Soybean cultivar 04324131
A soybean cultivar designated 04324131 is disclosed. The invention relates to the seeds of soybean cultivar 04324131, to the plants of soybean cultivar 04324131, to the plant parts of soybean cultivar 04324131, and to methods for producing progeny of soybean cultivar 04324131. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 04324131. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 04324131, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 04324131 with another soybean cultivar.
US08247659B1 Soybean variety XB14Z10
A novel soybean variety, designated XB14Z10 is provided. Also provided are the seeds of soybean variety XB14Z10, cells from soybean variety XB14Z10, plants of soybean XB14Z10, and plant parts of soybean variety XB14Z10. Methods provided include producing a soybean plant by crossing soybean variety XB14Z10 with another soybean plant, methods for introgressing a transgenic, mutant trait, and/or native trait into soybean variety XB14Z10, methods for producing other soybean varieties or plant parts derived from soybean variety XB14Z10. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB14Z10 are further provided.
US08247658B1 Soybean cultivar 05KG215810
The present invention is in the field of soybean cultivar 05KG215810 breeding and development. The present invention particularly relates to the soybean cultivar 05KG215810 and its progeny, and methods of making 05KG215810.
US08247655B2 Rucola plants with cytoplasmic male sterility (CMS)
The present invention discloses rucola plants, including an E. sativa plant, with cytoplasmic inherited male sterility (CMS) for hybrid breeding purposes. The present invention includes plants that comprise CMS-cytoplasm from cauliflower (B. oleracea var. botrytis) transferred to E. sativa by a wide interspecific cross.
US08247653B2 Delta-8 desaturase genes, enzymes encoded thereby and uses thereof
The present invention is related to isolated polynucleotides encoding a delta-8 desaturase, delta-8 desaturases encoded by the isolated polynucleotides, expression vectors containing the isolated polynucleotides, host cells containing the expression vectors and methods for producing delta-8 desaturases and polyunsaturated fatty acids.
US08247652B2 Population of transgenic plants individually comprising distinct codogenic gene segments, the population having at least 50% of the codogenic gene segments from a donor organism
The present invention relates to populations of trangenic plants encompassing a substantial part of all codogenic gene segments of a donor organism, and to biological material derived therefrom, plasmid collections and populations of transformed host organisms with which plants can be transformed in a suitable manner. There are also described methods for generating the plants and the material, and the use of the plants and of the material for functional studies. The codogenic gene segments are integrated into the genome of the plants. For example, there are described a population of plants of the species Arabidopsis thaliana into whose genome the codogenic gene segments from Saccharomyces cerevisiae are integrated, and their morphological analysis under normal conditions and stress conditions.
US08247648B2 Biological control of pathogenicity in microbes that use alpha, beta unsaturated fatty acid signal molecules
DSF-based microbial pathogens may be controlled by certain methods and compositions. A method of controlling diseases caused in a host organism by pathogenic microbial expression of α,β unsaturated fatty acid signal (DSF) molecules involves inoculating the host organism with a non-pathogenic microbe that disrupts α,β unsaturated fatty acid signal molecule-mediated cell-cell communication by the pathogenic microbe in the host organism. Microbes having protein expression that interferes with α,β unsaturated fatty acid signal molecule-mediated cell-cell communication by the pathogenic microbe in the host organism can be identified and isolated or engineered by transformation with DSF-interference (inhibition or activation) gene or genes. Genes conferring DSF-interference activity can also be expressed in organisms (e.g., plants) susceptible to diseases caused by microbes that use DSF, resulting in genetically resistant organisms.
US08247645B2 Method for providing cucumber fruits with an extended shelf life
A method for producing a Cucumis sativus plant, providing cucumber fruits exhibiting “extended shelf life, comprising: (a) providing a first Cucumis sativus plant containing at least one quantitative trait locus (QTL); (b) crossing the first plant with a second Cucumis sativus plant; (c) analyzing the progeny for presence or absence of QTL; and (d) identifying and selecting plants containing QTL. The QTL is selected from QTL1 or QTL2. QTL1 has a first molecular marker of SEQ ID No:1, a cucumber genomic fragment, and SEQ ID No:2, and a second molecular marker of SEQ ID No:3, a cucumber genomic fragment, and SEQ ID No:4. QTL2 has a first molecular marker of SEQ ID No:5, a cucumber genomic fragment, and SEQ ID No:6, and a second molecular marker of SEQ ID No:7, a cucumber genomic fragment, and SEQ ID No:8.
US08247644B2 Method for manufacturing animal model for researching pulmonary tumor and use thereof
The present invention is a method for manufacturing an animal model for researching a pulmonary tumor and a use thereof. A transgenic non-human animal of the present invention is prepared by embryonic gene microinjection and possesses a tissue-specific expression of vascular endothelial growth factor A165 (VEGF-A165) in lung. Through the expression of vascular endothelial growth factor A165, the lung cells in the transgenic non-human animal of the present invention have inflammatory, vascularogenesis and angiogenesis responses or induce lung tumors. Thus, the non-human animal of the present invention can serve as an animal model for analyzing the regulation and the anti-tumor drugs screening of pulmonary adenocarcinoma.
US08247637B2 Mini pad for reducing inflammation of the vulva and method of making the same
A mini pad is provided with a chilled skim milk additive which is useful for reducing vulvar inflammation and lowering the acidity of a female's vulva which result from vaginal secretions which leak onto the tissue of the vulva. The mini pad can be provided with a self-contained cooling component which can be frozen or, when compressed and ruptured, will lower the temperature of the mini pad to provide the soothing cold. The skim milk can be incorporated into the mini pad in several different ways. The mini pad is useful for soothing and healing vulvar irritation, and it is mobile and can be easily used during normal daily activities without any problems whatsoever.
US08247635B2 Wound dressing
A wound dressing includes an absorbent core defining opposed proximal and distal surfaces including a central portion and a border portion, and a liquid impervious, vapor permeable backing layer connected to the distal surface of the absorbent core. The backing layer defines a border portion extending beyond the periphery of the absorbent core. A skin adherent, perforated facing layer is secured to the proximal surface of the absorbent core. An adhesive layer is applied to at least a proximal segment of the border portion of the backing layer and has greater skin adherence properties than the facing layer.
US08247633B2 Energy generation process
High energy reaction of halogen-containing carbon, boron, silicon and nitrogen compounds, with base component comprising at least one atom selected from Groups IA to VIA, transition metals, lanthanides and actinides of the Periodic Table of the Elements, excluding aluminum and aluminum oxide.
US08247632B2 Process for the conversion of renewable oils to liquid transportation fuels
A method of producing a hydrocarbon product by hydrotreating a feedstock comprising triacylglyceride (TAG) and TAG-derived materials such as free fatty acid (FFA) and fatty acid methyl ester (FAME) in the presence of a nonsulfided hydrotreating catalyst to produce a first product comprising hydrocarbons. A method of producing a transportation fuel by selecting an undoped feedstock comprising virgin TAG, used TAG, FFA, and FAME or a combination thereof; hydrotreating the undoped feedstock in the presence of an unsulfided hydrotreating catalyst to produce a first product and subjecting the first product to at least one process selected from aromatization, cyclization, and isomerization to produce a second hydrocarbon product selected from gasoline, kerosene, jet fuel, and diesel fuels. A method is described by which fatty acids may be converted to hydrocarbons suitable for use as liquid transportation fuels. Additionally, the method allows for the blending of fatty acids with TAGs, and the conversion of such blends to hydrocarbons suitable for use as liquid transportation fuels. The method utilizes a catalyst and hydrogen as reductant to convert fatty acids to hydrocarbons. Subsequent steps, including dewatering, isomerization, and distillation, can provide a hydrocarbon mixture useful as a liquid transportation fuel or as a blendstock with petroleum transportation fuels.
US08247631B2 Process for catalytic cracking of hydrocarbons using UZM-35
Catalytic cracking processes such as fluidized catalytic cracking, naphtha cracking, and olefin cracking are catalyzed by the UZM-35 family of crystalline aluminosilicate zeolitic compositions represented by the empirical formula: Mmn+Rr+Al(1-x)ExSiyOz where M represents a combination of potassium and sodium exchangeable cations, R is a singly charged organoammonium cation such as the dimethyldipropylammonium cation and E is a framework element such as gallium. These UZM-35 zeolitic compositions are active and selective in the catalytic cracking of hydrocarbons.
US08247630B2 Process for C8 alkylaromatic isomerization
A process for isomerizing ethylbenzene into xylenes such as para-xylene using a zeolitic catalyst system based on low Si/Al2 MTW-type zeolite that preferably is substantially free of mordenite. The catalyst may be bimetallic where the two metals are platinum and tin.
US08247627B2 Process for producing phenol and/or cyclohexanone
In a process for producing phenol and/or cyclohexanone, benzene and hydrogen are contacted with a first catalyst in a hydroalkylation step to produce a first effluent stream comprising cyclohexylbenzene, cyclohexane, and unreacted benzene. At least part of the first effluent stream is supplied to a first separation system to divide the first effluent stream part into a cyclohexylbenzene-rich stream and a C6 product stream comprising unreacted benzene and cyclohexane.
US08247623B2 Catalytic process and apparatus for selective hydration of alkylene oxide
The present invention relates to an apparatus for the catalytic production of alkylene glycol from alkylene oxide, comprising: a reactor having at least one heat exchange element incorporated therein, wherein a catalyst for the hydration of alkylene oxide to alkylene glycol is coated on the outer surface of the heat exchange element. The present invention also relates to a process utilizing such an apparatus.
US08247622B2 Process for the preparation of phenol
A process is described for the preparation of phenol by the hydrodeoxygenation of polyhydroxylated benzene derivatives or by the selective hydroxylation of benzene under depletive conditions, characterized in that the above-mentioned reactions are carried out in the presence of a catalyst based on multi component metal oxides comprising at least one metal selected from the groups VB, VIB, VIII, IB, IIB, IVA, VA.
US08247621B2 Process for making 2-secondary-alkyl-4,5-di-(normal-alkyl)phenols
The invention relates to the preparation of alkylated phenols. More specifically, the invention relates to an improved process for the manufacture of 2-secondary-alkyl-4,5-di-normal-alkylphenols.
US08247619B2 BPA and polycarbonate made from renewable materials
Bio-derived bisphenol A is made by combining bio-derived phenol and/or bio-derived acetone in the presence of a catalyst, The phenol or the acetone or both contain at least 0.5%, for example at least 1 weight % of bio-derived impurities. In the case of bio-derived phenol, these impurities may include one or more of 2-methylbenzofuran, 2-methoxyphenol, 2-methylphenol, 4-methylphenol (para-cresol) or 2-methoxy-4-methylphenol. In the case of acetone, the impurity may be ethanol, mesityl acetone and/or diacetone alcohol. This bio-derived BPA can be used in the production of polycarbonates with less fossil fuel-based carbon content.
US08247618B2 Oxidative demetalling
Oxidative recovery methods that use oxygen or air for recovery of homogeneous metal catalysts, such as cobalt catalysts, used in for example hydroformylation processes, can be hazardous. Explosive or flammable gas mixtures may be generated inside the process equipment, which can deflagrate upon any ignition source such as a static electricity discharge. The use of a flammable diluent has been found to be a very effective way of optimizing the recovery method, by bringing the resulting gas mixtures above their upper flammability limit. The offgas produced is then also easier to dispose of as a fuel, as compared to when a non-flammable diluent is used.
US08247615B2 Process of converting esterified xanthophylls from Capsicum to non-esterified xanthophylls in high yields and purities
The present invention is concerned with a process to convert xanthophyll esters derived from Capsicum sources to their free (non-esterified) forms. The present invention is concerned with a process for obtaining Capsicum derived xanthophylls that meet the finished product needs for purity, yield, ease of use, industrial compatibility and cost that are required to make product suitable for the nutritional supplement, food and beverage industries. The present invention is concerned with a process which yields from 60 to 80%, of xanthophyll materials and nearly quantitative recovery of all input xanthophylls, which xanthophylls are of high purity. The present invention concerns a method to obtain xanthophyll esters present almost exclusively in the trans form when isolated from the natural plant sources. The present invention concerns a process to re-convert cis product back to the more desired trans form.
US08247612B2 Organic sulfur compound and its use for controlling harmful arthropod
There is provided an organic sulfur compound having an excellent controlling effect on harmful arthropods represented by the formula (I): wherein, R1 represents a C1-C5 haloalkyl group having at least one fluorine atom, R2 represents a C1-C4 alkyl group optionally substituted with at least one halogen atom or the like, R3 represents a hydrogen atom or the like, R4 represents a cyano group or the like, R5 represents a hydrogen atom or the like, m represents an integer of 1 to 4, and n represents 0, 1 or 2.
US08247611B2 Process for producing nitrogen-containing compounds
The present invention relates to a process for producing an aliphatic amine, comprising the step of contacting a linear or branched, or cyclic aliphatic alcohol having 6 to 22 carbon atoms with ammonia and hydrogen in the presence of a catalyst formed by supporting at least (A) a ruthenium component produced by hydrolysis of a ruthenium compound on a carrier, or by further supporting, in addition to the component (A), a specific second metal component or a specific third metal component on the carrier. According to the process of the present invention, an aliphatic primary amine can be produced from an aliphatic alcohol with a high catalytic activity and a high selectivity.
US08247606B2 Process for the preparation of cilastatin and sodium salt
An improved process for preparing Cilastatin Sodium including dissolving Cilastatin acid in a solvent using an organic base, adding sodium salt of a week acid and isolating Cilastatin Sodium.
US08247603B2 Deuterated catecholamine derivatives and medicaments comprising said compounds
The present invention concerns deuterated catecholamine derivatives as well as pharmaceuticals containing these compounds. In addition, the invention concerns the use of deuterated catecholamine derivatives as well as physiologically acceptable salts thereof, and also pharmaceutical compositions, which contain these compounds, also in combination with enzyme inhibitors, for the treatment of dopamine deficiency diseases or diseases which are based on disrupted tyrosine transport or disrupted tyrosine decarboxylase, as well as other disorders.
US08247601B2 2-acrylamide-2-methylpropanesulfonic acid and process for producing the same
A process for producing 2-acrylamide-2-methyl propane sulfonic acid (ATBS) which comprises reacting acrylonitrile, fuming sulfuric acid, and isobutylene. During the reaction, the concentration of 2-methyl-2-propenyl-1-sulfonic acid (IBSA) and/or that of 2-methylidene-1,3-propylenedisulfonic acid (IBDSA) in the reaction system are determined. When the IBSA concentration exceeds 12,000 mass ppm and/or the IBDSA concentration exceeds 6,000 mass ppm, then the concentration of sulfur trioxide in the reaction system is reduced. Thus, ATBS having an IBSA content of 100 mass ppm or lower and an IBDSA content of 100 mass ppm or lower is produced.
US08247594B2 Insecticidal compounds
A compound of formula (I), wherein A1, A2, A3, A4, R1, R2, R3, G1, G2, G3 and Q are as defined in claim 1; or a salt or N-oxide thereof. Furthermore, the present invention relates to processes and intermediates for preparing compounds of formula (I), to insecticidal, acaricidal, molluscicidal and nematicidal compositions comprising them and to methods of using them to combat and control insect, acarine, mollusc and nematode pests.
US08247593B2 Process for preparing substituted 7-cyano quinone methides
A one-pot process of preparing a substituted 7-cyano quinone methide in which i) a substituted phenol is chloromethylated to form a substituted 4-chloromethylphenol; ii) converting the substituted 4-chloromethylphenol to a substituted 4-cyanomethylphenol; and iii) oxidizing the substituted 4-cyanomethylphenol to the substituted 7-cyano quinone methide, where steps i)-iii) are carried out in a single reaction vessel in a solvent system comprising water and one or more organic solvents and where after steps i) and ii) the aqueous portion of the reaction mixture is removed and the reagents for the subsequent step are added in aqueous solution. The 7-cyano quinone methides are effective inhibitors of the polymerization of reactive monomers.
US08247590B2 Method for preventing polymerization of unsaturated organosilicon compounds
Undesired polymerization of (meth)acrylatoalkoxysilanes during their industrial preparation and handling is accomplished by avoiding contact with surfaces containing more than 1% by weight of iron.
US08247589B2 Organic silicon phosphate and fabrication method thereof
The invention provides an organic silicon phosphate and fabrication method thereof. The organic silicon phosphate has formula (I): wherein R1 and R2 are the same or different and represent C1-C5 alkyl; R3 and R4 are the same or different and represent hydrogen, C1-C5 alkyl; R5 is aryl or C1-C5 alkyl; Y is a linking bond containing —CH2—, —C(CH3)2—, —S—, —SO2—, —O—, —CO—, or —N═N—; m is an integer from 0 to 4; n is 0 or 1 and k is an integer from 0 to 9.
US08247586B2 Methods of making layered mixed-metal phosphonates for high dielectric strength polymer nanocomposites
Multi-metal phosphonates are generally provided. The multi-metal phosphonate can generally have the composition: AB(RPO3)3, where A is Mg2+, Ca2+, Sr2+, Ba2+, Pb2+, La3+, or combinations thereof; B is Ti4+, Zr4+, Al3−, or combinations thereof; and R is an organic group (e.g., aryl group, an alkyl group, an alkenyl group, etc.). The multi-metal phosphonate can be combined with a polymeric material to form a polymeric film. Methods of making the multi-metal phosphonate by combining and reacting a metal oxide and an organophosphonic acid are also provided.
US08247582B2 Esters of 5-hydroxymethylfurfural and methods for their preparation
Disclosed are compositions and methods for the production of mono-esters and di-esters from the reaction of HMF and a reactant selected from a diacid or a diacid derivative; typical reactants are PAN, phthaloyl dichloride, dimethyl phthalate, maleic acid, and maleic anhydride or mono-esters that can be prepared from HMF and MAN.
US08247581B2 Process for converting cellulose in a liquid biofuel using N-methyl imidazolium chloride
Process for converting cellulose and hemicellulose in hydroxymethylpyranone and isomers, using as a solvent and catalyst a mixture of N alkyl imidazolium chloride and hydrochloric acid 37%, where hydroxymethylpyranone is extracted with butanol and hydrogenated to methylpyran and isomers.
US08247580B2 Process for preparing ε-caprolactone
The present invention provides a process for preparing ε-caprolactone in a purity of more than 99% by cyclizing 6-hydroxycaproic esters in the liquid phase at from 150 to 400° C. and from 1 to 1020 hPa abs., and removing and condensing the compounds which are volatile under cyclization conditions, which comprises thermally treating the remaining bottom product of the cyclization in at least one further reactor, removing and condensing volatile compounds and obtaining ε-caprolactone by distillation from the condensates.
US08247577B2 Optical recording material and cyanine compound
An optical recording material comprising at least one kind of a cyanine compound represented by the following general formula (I): wherein ring A and ring B each independently represent a benzene ring or a naphthalene ring which may have a substituent; R1 represents a group represented by the general formula (II), (II′) or (II″); R2, R3 and R4 each independently represent a hydrogen atom, an organic group having 1 to 30 carbon atoms, or a group represented by the general formula (II), (II′) or (II″); R3 and R4 may be linked together to form a ring structure; Y1 and Y2 each independently represent an organic group having 1 to 30 carbon atoms or a group represented by the general formula (III); X represents a hydrogen atom, a halogen atom, an alkyl group having 1 to 4 carbon atoms, a phenyl group which may have a substituent, a benzyl group which may have a substituent, or a cyano group; Anm− represents an m-valent anion; m is 1 or 2; and p represents a coefficient keeping the charge neutral.
US08247575B2 Carbazole derivative with heteroaromatic ring, and light-emitting element, light-emitting device, and electronic device using carbazole derivative with heteroaromatic ring
Disclosed is a carbazole derivative and a light-emitting element, a light-emitting device, and an electronic device using thereof. The carbazole derivative possesses an oxadiazole moiety or a quinoxaline moiety as a heteroaromatic ring having an electron-transporting property and a carbazole moiety having a hole-transporting property. The ability of the carbazole derivative to transport both electrons and holes and its large excitation energy larger than a triplet excitation energy of a phosphorescent compound allow the formation of a phosphorescent light-emitting element having well-controlled carrier balance, which contributes to the formation of light-emitting devices and electronic devices that are capable of being driven at a low voltage, have a long lifetime, and consume low power. The detailed structure of the carbazole derivative is defined in the specification.
US08247573B2 Substituted N-(2-mercaptopyridin-3-yl)amides as KCNQ2/3 modulators
The invention relates to substituted N-(2-mercaptopyridin-3-yl)amides, methods for the preparation thereof, medicaments containing these compounds and the use of these compounds for the preparation of medicaments.
US08247570B2 Process for preparing 2-amino-5-cyanobenzoic acid derivatives
Disclosed is a method for preparing a compound of Formula 1 comprising contacting a compound of Formula 2 with a metal cyanide reagent, a copper(I) salt reagent, an iodide salt reagent and at least one compound of Formula 3 wherein R1 is NHR3 or OR4; R2 is CH3 or Cl; R3 is H, C1-C4 alkyl, cyclopropyl, cyclopropylcyclopropyl, cyclopropylmethyl or methylcyclopropyl; R4 is H or C1-C4 alkyl; X is Br or Cl; and R5, R6, R7, R8 and R9 are as defined in the disclosure. Also disclosed is a method for preparing a compound of Formula 4 wherein R12, R13, R14 and Z are as defined in the disclosure, using a compound of Formula 1 characterized by preparing the compound of Formula 1 by the method disclosed above or using a compound of Formula 1 prepared by the method disclosed above.
US08247565B2 Sirtuin modulating compounds
Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benfit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent.
US08247564B2 Compounds having BETA2 adrenergic receptor agonist and muscarinic receptor antagonist activity
The invention is directed to compounds of formula I: wherein R1, R2, R3, R4, R5, R6, R7a, R7b, W, G1, G2, a, b, c, d and m are as defined in the specification, or a pharmaceutically acceptable salt or solvate or stereoisomer thereof. The invention is also directed to pharmaceutical compositions comprising such compounds; methods of using such compounds; and process and intermediates for preparing such compounds.
US08247563B2 Compositions, synthesis, and methods of using indanone based cholinesterase inhibitors
The present invention provides novel indanone derivatives which can be advantageously used for treating and/or preventing of a medical condition for which inhibition of a cholinesterase is desired.
US08247561B2 Preparation of methylpentamethylenediamine and methylpiperidine
Methyl-2-pentamethylenediamine and methyl-3-piperidine are prepared by hydrogenation of methylglutaronitrile in the presence of a catalyst including cobalt, chromium, and nickel, especially a catalyst based on Raney cobalt doped with nickel and chromium.
US08247560B2 Trisubstituted 3,4-dihydro-1H-isoquinolin compound, process for its preparation, and its use
The present invention relates to the compound of formula 7*acetate (see below), a process for its preparation, and its use
US08247555B2 Crystalline forms of an 8-azabicyclo[3.2.1]octane compound
The invention provides a crystalline sulfate salt of 3-endo-(8-{2-[cyclohexylmethyl-((S)-2,3-dihydroxy-propionyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)benzamide or a solvate thereof. The invention also provides pharmaceutical compositions comprising such crystalline salt forms, methods of using such crystalline salt forms to treat diseases associated with mu opioid receptor activity, and processes useful for preparing such crystalline salt forms.
US08247551B2 Lead sensor and methods of use
A fluorophore that forms a complex with Pb ions is disclosed. The fluorophore/lead complex fluoresces with an intensity greater than complexes formed by the fluorophore with other metals. The fluorophore may be used as a sensor/detector for lead ions in various samples. Methods for detecting and calculating the concentration of lead ions in samples are also disclosed.
US08247546B2 Derivatives of acid polysaccharides
Acid polysaccharides characterized by the concomitant presence of partial esters with non-polysaccharide carboxylic acids and esters between the acid groups of the initial polysaccharide and the alcohol groups of the repetitive units, with the formation of crosslinking among the polysaccharide chains.
US08247540B2 Caged nucleotides and oligonucleotides and their application
There is disclosed nucleotides and nucleotide analogs having a protecting or “caging” group. There is further disclosed oligonucleotides and oligonucleotides analogs formed having a protecting or “caging” group. There is further disclosed a method for decaging the nucleotides and nucleotide analogs having a protecting or “caging” group and oligonucleotides and oligonucleotide analogs having a caging group.
US08247538B2 Preparation method of radioisotope labeling compound using carbon nanotube
Disclosed herein is a method for the preparation of radioisotope-labeled compounds using CNT. It comprises filling the carbon nanotube with a radioisotope; and labeling a physiologically active material with the radioisotope charged in the carbon nanotube. Taking advantage of CNT, the method can prepare a radioisotope-labeled compound invention at a high yield and in a simple manner. Also, the radioisotope, when remaining unreacted, can be recovered by the filtration of the CNT, thereby achieving the prevention of radioactive contamination and the reduction of radioactive waste. Further, the radioisotope-labeled compound is useful as a contrast medium for imaging the hepatobiliary system.
US08247531B2 Mutant epidermal growth factor polypeptides, nucleic acids, and uses therefor
The present invention is based, in part, on our discovery that EGF can be engineered to generate mutants that bind to the EGF receptor (EGFR) of a cell and that have a desirable effect on the activity of the cell. For example, the mutants can agonize the receptor (i.e., increase a biological activity of the receptor), or antagonize the receptor (i.e., decrease or inhibit a biological activity of the receptor). In turn, the rate at which the cell proliferates, for example, can be changed. Moreover, some of these mutants bind EGFR with a higher affinity than wild-type EGF exhibits. The affinity may increase by about, for example, 2-, 5-, 10-, 15-, 20-, 25-, 30-, 50-, or 100-fold relative to wild-type EGF.
US08247525B2 Particles and composite particles, their uses and a novel process for producing them from alkoxysilyl-group-carrying alkoxylation products
The present invention related to particles and composite particles, their uses and a novel process for producing them from alkoxysilyl-group-carrying alkoxylation products.
US08247524B2 Preparation of supramolecular polymers containing quadruple hydrogen bonding units in the polymer backbone
The present invention relates to a supramolecular polymer comprising quadruple hydrogen bonding units within the polymer backbone, wherein at least a monomer comprising a 4H-unit is incorporated in the polymer backbone via at least two reactive groups up to four reactive groups, provided that the 4H-units are not covalently incorporated in the polymer backbone through one or more silicon-carbon bonds. The invention also relates to processes for preparing such supramolecular polymers and their use in personal care applications, surface coatings, imaging technologies, biomedical applications, (themo)reversible coatings, adhesive and sealing compositions and as thickening agents, gelling agents and binders.
US08247523B2 Methods for producing and purifying 2-aryl-3,3-bis(4-hydroxyaryl)phthalimidine compounds, the purified monomers, and polymers derived therefrom
Disclosed herein is a method for producing a purified 2-aryl-3,3-bis(4-hydroxyaryl) phthalimidine of formula (I) wherein R1 is hydrogen or a C1-25 hydrocarbyl group and R2 is a hydrogen, a C1-25 hydrocarbyl group, or a halogen, and wherein the method comprises dissolving a crude phthalimidine compound in an aqueous base solution; precipitating the dissolved, crude phthalimidine compound from the aqueous base solution by adding an acid in an amount effective to lower the pH of the solution to 9.0 to 12.0, to provide a semicrude phthalimidine compound; and isolating the semicrude phthalimidine compound from the aqueous base solution, to provide the purified 2-aryl-3,3-bis(4-hydroxyaryl)phthalimidine of formula (I), and having a phenolphthalein compound content of less than 2,500 ppm, based on the weight of the purified 2-aryl-3,3-bis(4-hydroxyaryl)phthalimidine. Subsequent trituration with aqueous methanol and recrystallization from isopropanol can result in product having levels of phenolphthalein derivatives that are not detectable.
US08247517B2 Catalyst for curing epoxides
The use of 1,3-substituted imidazolium salts of the formula I in which R1 and R3 independently of one another are an organic radical having 1 to 20 C atoms, R2, R4, and R5 independently of one another are an H atom or an organic radical having 1 to 20 C atoms, it also being possible for R4 and R5 together to form an aliphatic or aromatic ring, and X is a dicyanamide anion as latent catalysts for curing compositions comprising epoxy compounds.
US08247516B2 Room-temperature curable organopolysiloxane composition
A room-temperature curable organopolysiloxane composition comprising: (A) a diorganopolysiloxane capped at both molecular terminals with trialkoxysilyl groups and having viscosity of 100 to 1,000,000 mPas at 25° C.; (B) a diorganodimethoxysilane or a partially hydrolyzed product thereof; (C) a diorganodialkoxysilane having silicon-bonded alkoxy group with two or more carbon atoms or a partially hydrolyzed product thereof; and (D) a titanium chelate catalyst, exhibits excellent storage stability and easiness of controlling curing speed as well as by strong adhesion to a substrate with which this composition is in contact during curing along with the possibility of interfacial peeling of the cured product from the aforementioned substrate.
US08247515B2 Amphiphilic grafts and co-networks and process for making same
The present invention generally relates to amphiphilic grafts and co-networks made from at least one hydrophilic polymer and at least one hydrophobic polymer, and to processes for preparing such amphiphilic grafts and co-networks. In another embodiment, the present invention relates to amphiphilic co-networks formed from the combination of at least one polysiloxane and at least one polyacrylamide. In yet another embodiment, the present invention relates to amphiphilic co-networks formed from the combination of at least one polysiloxane, at least one polyacrylamide and at least one crosslinking agent.
US08247511B2 Water plasticized high refractive index polymer for ophthalmic applications
The current invention provides a method of forming a foldable intraocular having a high refractive index from a copolymer comprising a first monomer comprising an aryl acrylate or an aryl methacrylate; a second monomer comprising an aromatic ring comprising a substituent having one ethylenic unsaturation, provided that the second monomer is not an aryl acryate or aryl methacrylate, and a third monomer comprising one ethylenic unsaturation that, if polymerized into a homopolymer, forms a high water content hydrogel; and, optionally, a cross-linking agent.
US08247508B2 Isobutylene-based polymer and method for producing same
An isobutylene-based polymer comprising a structural unit represented by the following formula (1): and a structural unit represented by the following formula (2): wherein X represents a divalent group; Y represents a substituted or unsubstituted alicyclic group having an unsaturated bond in the ring; and n represents 0 or 1.
US08247507B2 Cationic polymers as thickeners for aqueous and alcoholic compositions
The present invention relates to a method for producing polymers by radically polymerizing a mixture comprising 99.99 to 10% by weight of at least one α,β-ethylenically unsaturated compound with at least one cationogenic and/or cationic group per molecule, 0 to less than 25% by weight of at least one monoethylenically unsaturated amide-group-containing compound different from a) and also 0.01 to 5% by weight of a crosslinker using at least two different water-insoluble initiators.
US08247503B2 Adhesive composition and adhesive sheet
The object of the present invention is to provide an adhesive composition which can form a thinner adhesive layer, which has good storage stability and which can actualize high package reliability even when exposed to severe reflow conditions in a semiconductor package in which a semiconductor chip being reduced in a thickness is mounted, and an adhesive sheet having an adhesive layer comprising the adhesive composition.The adhesive composition of the present invention comprises an epoxy thermosetting resin (A), a thermosetting agent (B) and a thermosetting accelerating agent (C); the thermosetting accelerating agent (C) being soluble in methyl ethyl ketone and inactive as a thermosetting accelerating agent at room temperature.
US08247501B2 Lubricant compositions and methods of making same
Compositions are described that include a) from 15 weight percent to 60 weight percent of one or more random alkylene oxide interpolymers, each having a weight average molecular weight ranging from 250 g/mol to 2000 g/mol and comprising from 30 weight percent to 60 weight percent of polymer units derived from ethylene oxide; and b) from 40 weight percent to 85 weight percent of one or more alkylene oxide block interpolymers, each having a weight average molecular weight ranging from 1500 g/mol to 4000 g/mol and comprising from 40 weight percent to 90 weight percent propylene oxide blocks. The compositions have a first viscosity in the absence of water and a second viscosity that is at least 60 percent of the first viscosity when at least 10 weight percent water is present. Methods of lubricating surfaces, particularly, marine bearing surfaces with such compositions, are also described.
US08247495B2 Elastomeric polymer blends and processes for their production
Elastomeric polymer blends and processes for their production are described. Specifically, the polymer blends comprise a first polymer and a second polymer, where the first polymer comprises from about 70 wt % to about 90 wt % units derived from propylene and from about 10 wt % to about 30 wt % units derived from ethylene and/or a C4-C10 alpha-olefin, and the second polymer comprises from about 88 wt % to about 98 wt % units derived from propylene and from about 2 wt % to about 12 wt % units derived from ethylene and/or a C4-C10 alpha-olefin. The elastomeric polymer blends are further characterized by having two or more of the following properties: an overall propylene content of between about 75 wt % and about 90 wt %, a melting point between about 110° C. and about 145° C., a Vicat softening point greater than about 45° C., a tensile stress at 300% strain of less than about 500 psi (3447 kPa), as determined by a stress strain test according to ASTM D412, or an average maximum force for pellet separation of less than about 10 N in an accelerated storage stability test. The polymer blends are produced in a dual reactor process, in which the first polymer and the second polymer are prepared using differing catalyst systems.
US08247494B2 Thermoset compositions with dispersed thermoplastic resin therein and process for making them
A rubber composition comprising: a cured rubber; and thermoplastic resin, where the thermoplastic resin is in the form of discrete domains dispersed within a continuous phase of the cured rubber, and where the cured rubber includes silicon-containing crosslinks.
US08247489B2 Rubber composition
Provided is a rubber composition blended with an inorganic filler, the rubber composition having an improved dispersibility of the inorganic filler, as well as improved low heat generation property and tensile stress. The rubber composition includes a blend of: 100 parts by weight of a diene rubber; 1 to 150 parts by weight of an inorganic filler; and 0.1 to 30 parts by weight of a copolymer composed of a segment composed of a polyamide polymer and a segment composed of a diene polymer. The segment composed of the diene polymer has a number average molecular weight of not less than 10000.
US08247488B2 Modified polyacrylamide hydrogel
The invention relates to a salt resistant water absorbing compound including a polymeric phase that includes polyacrylamide and at least one of di or poly saccharide, wherein the polyacrylamide is cross-linked in the presence of at least one of di or poly saccharide by a cross-linking agent including multivalent cations, complexes thereof, organic cross-linking agents, or any combination thereof.
US08247486B2 Creep resistant fluoropolymer
Creep resistant fluoropolymer is made by blending a melt-fabricable fluoropolymer having a melt flow rate of no greater than about 7 g/10 min with milled carbon fiber and forming the resultant blend into an article, the carbon fiber content of the blend being from about 15 to 35 wt % based on the combined weight of the carbon fiber and the fluoropolymer.
US08247483B2 Rotation molded body
A rotation molded body obtained by rotation molding of a polyolefin composition comprising a polyolefin and a phosphite of the formula (I).
US08247482B2 Hydrophilic polyisocyanate compositions based on phosphate esters
The invention relates to a composition comprising at least one (poly)isocyanate and at least one surfactant comprising an amino acid and a mixture of compounds of formulae (I) and (II) wherein i and j independently represent 0 or 1; and R1 et R2 are identical or different and independently represent a hydrocarbonated chain. Said mixture of compounds of formulae (I) and (II) is characterized in that the molar ratio between compound (II) and compound (I) is higher than 1.
US08247480B2 PVC compositions
A PVC composition comprising PVC and a C4-C30 alkyl pyrrolidone additive present in an amount of 0.1 to 20 phr sufficient to improve PVC processing or treatment compared to a control composition without said additive.
US08247479B2 Symmetric azo compounds in flame retardant compositions
The invention, relates to azo-compounds of formula (I), wherein >N—O—R substituted 2,2,6,6-tetraalkyl-piperidyl groups are present. These azo-compounds have excellent flame retardant properties, either if applied alone, or combined with other compounds, having flame retardant properties.
US08247477B2 Polybutylene terephthalate resin composition exhibiting an improved glow-wire ignition temperature for insulating parts
Provided is a polybutylene terephthalate resin composition for insulating parts, which satisfies GWIT Standard over a thickness range of 0.75 to 3 mm, the thickness range having been accepted as difficult to satisfy the Standard. In detail, to (A) 100 parts by weight of a polybutylene terephthalate resin, there are added (B) 5 to 50 parts by weight of a halogen-based flame retardant, (C) 5 to 50 parts by weight of a flame retardant assistant, (D) 1 to 100 parts by weight of a nitrogen-based compound, and (E) 0 to 200 parts by weight of a fibrous reinforcement.
US08247474B2 Method of manufacturing base layer, ink for inkjet and electronic components
A base layer is formed on the surface of metal plate, metal pipe, unbaked ceramic sheet, laminated ceramic green sheet, etc., the base layer causing a gelling reaction with inkjet-ink. The base layer improves ink acceptability for low viscosity inks such as inkjet-ink, and prevents oozing, draining, uneven thickness of an ink pattern and a resist pattern. Thus, the present invention enables to use an ink jet process for providing resist patterns for etching, etc., which has to fulfill stringent high precision requirements.
US08247467B2 Process for producing flexible polyurethane foams
The invention relates to a process for producing flexible polyurethane foams by reacting a) polyisocyanates with b) compounds having at least two hydrogen atoms which are reactive toward isocyanate groups in the presence of c) blowing agents, wherein the component b) comprises at least one polyether carbonate polyol bi) which can be prepared by addition of carbon dioxide and alkylene oxides onto H-functional starter substances using DMC catalysts and has a functionality of at least 2, a hydroxyl number in the range from 10 to 500 mg KOH/g and a content of incorporated carbon dioxide in the form of carbonate units of at least 2% by weight.
US08247461B2 Ophthalmic and contact lens solution
An ophthalmic solution comprising a polyethoxylated glyceride in the range of 0.001 to about 10 percent by weight and a buffer agent. These solutions impart surprising comfort and wearability to contact lenses. At the same time the solutions provide good preservative capacity and do not increase protein deposit.
US08247458B2 Therapeutic agent for diabetic neuropathy
A therapeutic agent for the treatment of diabetic neuropathy which comprises (±)-[2-[4-(3-ethoxy-2-hydroxypropoxy)phenylcarbamoyl]-ethyl]dimethylsulfonium p-toluenesulfonate of the formula (1) as an active ingredient.
US08247456B2 Dosing regimes for trans-clomiphene
The present invention relates to the use of compositions comprising trans-clomiphene for treating men with hypogonadism. The invention is also directed to methods for treating males with hypogonadism and disorders related thereto, including reduction of muscle mass, limitation of body performance capacity, reduction of bone density, reduction of libido, reduction of potency, reduction of benign prostatic hyperplasia and infertility.
US08247450B2 Linoleic acid active agents for enhancing probability of becoming pregnant
The present invention is directed to a methods and compositions for enhancing the probability that a subject will become pregnant. The method comprises administering to a subject a pharmaceutical composition comprising an effective amount of a linoleic acid active agent, e.g., linoleic acid, a polyunsaturated fatty acid analog thereof, etc. Also provided are kits that find use in practicing the subject methods. The subject methods and compositions find use in a variety of different applications, including but not limited to the treatment of infertility conditions.
US08247446B2 Insecticidal compositions suitable for use in preparation of insecticidal granular fertilizer and insecticidal formulations
Insecticidal compositions suitable for use in preparation of insecticidal granular fertilizer and insecticidal formulations comprising a pyrethroid and a glycol present in a concentration of from 40.0% by weight to 99.0% by weight based upon the total weight of all components in the composition is disclosed.
US08247442B2 Benzenesulfonamide compounds and their use
The invention relates to azetidinyl, pyrrolidinyl, piperidinyl, and hexahydroazepinyl compounds of Formula I and pharmaceutically acceptable salts, prodrugs, or solvates thereof, wherein R1-R3 and Z are defined as set forth in the specification. The invention is also directed to the use compounds of Formula I to treat, prevent or ameliorate a disorder responsive to the blockade of calcium channels, and particularly N-type calcium channels. Compounds of the present invention are especially useful for treating pain.
US08247441B2 Chromene compounds, a process for their preparation and pharmaceutical compositions containing them
The invention relates to compounds of formula (I): wherein R1 and R2 together form the following carbon-containing chain: wherein: R3 represents a hydrogen atom or an alkyl group, R4 represents a hydrogen atom or an alkyl, aryl, heteroaryl, 3,4-dioxocyclobutenyl, alkylcarbonyl, cycloalkylcarbonyl, heterocycloalkylcarbonyl, benzoyl, arylsulphonyl or heteroarylsulphonyl group, each of those groups optionally being substituted, or R3 and R4 together with the nitrogen atom carrying them form a 5- to 8-membered ring, the ring thereby formed optionally being substituted. Medicinal products containing the same which are useful in treating conditions requiring a D3 receptor antagonist.
US08247440B2 Composition comprising omeprazole, lansoprazole and at least one buffering agent
The present disclosure relates to pharmaceutical compositions comprising omeprazole, lansoprazole and at least one buffering agent.
US08247436B2 Pyridine and pyrazine derivative for the treatment of CF
The present invention provides pyridine and pyrazine derivatives which restore or enhance the function of mutant and/or wild type CFTR to treat cystic fibrosis, primary ciliary dyskinesia, chronic bronchitis, chronic obstructive pulmonary disease, asthma, respiratory tract infections, lung carcinoma, xerostomia and keratoconjunctivitis sire, or constipation (IBS, IBD, opioid induced). Pharmaceutical compositions comprising such derivatives are also encompassed.
US08247434B2 Fexofenadine polymorphs and processes of preparing the same
Anhydrous crystalline fexofenadine hydrochloride Form C, crystalline fexofenadine acetate monohydrate Form D, crystalline fexofenadine acetate dihydrate Form E and crystalline fexofenadine free base monohydrate Form F, processes of preparing the same, pharmaceutical compositions thereof, therapeutic uses thereof and methods of treatment therewith.
US08247431B2 Heterocyclic hydrazide compound and pesticidal use of the same
A hydrazide compound represented by the formula (I), an N-oxide thereof or suitable salt thereof: has excellent pesticidal activity.
US08247430B2 Substituted aryl-amine derivatives and methods of use
Selected amines are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds of Formula I and II wherein R, R1 and R2 for each formula are defined herein. The invention further includes analogs, prodrugs and pharmaceutically acceptable salts and derivatives of Formulas I and II, as well as pharmaceutical compositions, medicaments and methods thereof for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
US08247427B2 Dual phase drug release system
The present invention relates to conjugate comprising a carrier substituted with one or more occurrences of a moiety having the structure: wherein each occurrence of M is independently a modifier having a molecular weight ≦10 kDa; denotes direct of indirect attachment of M to linker LM; and each occurrence of LM is independently an optionally substituted succinamide-containing linker, whereby the modifier M is directly or indirectly attached to the succinamide linker through an amide bond, and the carrier is linked directly or indirectly to each occurrence of the succinamide linker through an ester bond. In another aspect, the invention provides compositions comprising the conjugates, methods for their preparation, and methods of use thereof in the treatment of various disorder, including, but not limited to cancer.
US08247422B2 Use of condensed pyrimidine derivatives for the treatment of rheumatoid arthritis
The invention relates to the use of a compound of the formula (I), or a pharmaceutically acceptable salt thereof, for the manufacture of a medicament for use in modulating an immune or inflammatory response: wherein: Z=O or S; n=1-3; R3=—CO2R8, —C(O)SR8, —C(O)NHR8, —C(S)OR8, —C(S)SR8, —C(S)NHR8, —C(NH)SR8 or —C(NH)NHR8, wherein R8 is —H or alkyl; R4=—H, —CH2R5 or —CH2CH2R5, wherein R5 independently has one of the meanings of R3; B=—NR2—, —CH2NR2—, —CH2CH2NR2—, —CH2CHR7— or —CH2O—, wherein R2 is H or a C1-3 alkyl, alkenyl or alkynyl group, and R7 is H or a C1-3 alkyl or alkoxy group; A=wherein R1=—NH2 or —OH, C and D are each, independently, a 5- or 6-membered, substituted or unsubstituted, aromatic or non-aromatic ring which may also contain one or more heteroatoms, and C is connected to group B in any available position.
US08247421B2 5-cyano-4-(pyrrolo [2,3B] pyridine-3-yl)-pyrimidine derivatives useful as protein kinase inhibitors
The present invention relates to compounds useful as inhibitors of protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the inventions.
US08247418B2 Pyrazine compounds as phosphodiesterase 10 inhibitors
Pyrazine compounds, and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, bipolar disorder, obsessive-compulsive disorder, and the like.
US08247415B2 Hydroxymethyl pyrrolidines as β3 adrenergic receptor agonists
The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
US08247413B2 Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor
Compounds of formula (I) are novel VR1 antagonists that are useful in treating pain, inflammatory thermal hyperalgesia, urinary incontinence and bladder overactivity, wherein X1, X2, X3, X4, X5, R5, R6, R7, R8a, R8b, R9, Z1, Z2 and L are as defined in the description.
US08247410B2 Pyrimidine substituted purine derivatives
The present invention relates to purine compounds that are useful as kinase inhibitors. More particularly, the present invention relates to purine compounds, methods for their preparation, pharmaceutical compositions containing these compounds and uses of these compounds in the treatment of proliferative conditions or disorders. These compounds may be useful as medicaments for the treatment of a number of proliferative conditions or disorders including tumors and cancers as well as other disorders or conditions related to or associated with PI3 and/or mTOR kinases.
US08247409B2 Thieno-[2,3-d]pyrimidine and thieno-pyridazine compounds and methods of use
The present invention comprises a new class of compounds useful for the prophylaxis and treatment of protein kinase mediated diseases, including inflammation and related conditions. The compounds have a general Formula I wherein A1, A2, B, R2 and R3 are defined herein. The invention also comprises pharmaceutical compositions including one or more compounds of Formula I, uses of such compounds and compositions for treatment of kinase mediated diseases including rheumatoid arthritis, psoriasis and other inflammation disorders, as well as intermediates and processes useful for the preparation of compounds of Formula I.
US08247408B2 Pyridopyrimidinone inhibitors of PI3Kα for the treatment of cancer
The invention is directed to Compounds of Formula I and pharmaceutically acceptable salts or solvates thereof, as well as methods of making and using the compounds.
US08247405B2 Skin lightening compositions with acetylcholinesterase inhibitors
Skin lightening additives and skin lightening compositions having an acetylcholinesterase inhibitor are described. The compositions are suitable for topical application and may comprise inhibitors like galanthamine, taspine or both.
US08247403B2 Benzoxazepine derivatives and use thereof
Compounds represented by the general formula (I): wherein each symbol is as defined in the description [with the proviso that 9-chloro-7-(1,1-dimethylethyl)-2,3,4,5-tetrahydro-1,4-benz-oxazepine and N-[[(5S)-2-oxo-3-(2,3,4,5-tetrahydro-1,4-benz-oxazepin-7-yl)-5-oxazolidinyl]methyl]acetamide are excluded], salts of the same, and prodrugs thereof have selective activation effect on serotonin 5-HT2C receptor and are useful as preventive and therapeutic agents for lower urinary tract diseases, obesity, and/or pelvic organ prolapse.
US08247402B2 Crystal form of pyrrolidylthiocarbapenem derivative
Novel crystals of a pyrrolidylthiocarbapenem derivative having excellent stability is provided. According to the present invention, a crystal of (+)-(4R,5S,6S)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-3[[(3S,5S)-5-(sulfamoylaminomethyl)p yrrolidin-3-yl]thio]-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid having a diffraction pattern in powder X-ray diffraction having main peaks at diffraction angles (2θ) of about 13.04, 14.98, 15.88, 16.62, 20.62, 21.06, 22.18, 23.90, 26.08, 28.22 and 28.98 (degrees) and a crystal of said compound having a diffraction pattern in powder X-ray diffraction having main peaks at diffraction angles (2θ) of about 6.62, 13.04, 15.44, 16.58, 17.64, 20.88, 23.26, 25.02 and 25.52 (degrees) are provided.
US08247400B2 Cephem compounds useful for the treatment of bacterial infections
The present invention relates to new cephem compounds useful for the treatment of bacterial infections of formula I: The invention also relates to methods of preparing the compounds, pharmaceutical compositions comprising the compounds, and to methods of treatment using the compounds. The new cephem compounds are stable, exhibit good solubility, and are particularly well suited for, e.g., parenteral administration for the treatment of bacterial infections.
US08247395B2 Topical skin care composition
A cream base for the topical application of skin care therapeutics and a process for making the cream base. In one embodiment, the therapeutic is tretinoin, hydroquinone and fluocinolone acetonide for the treatment of hyperpigmented skin conditions, such as melasma.
US08247394B2 Methods of treating urethritis and related infections using fusidic acid
Methods for the treatment and prevention of a bacterial infection caused by Neisseria gonorrhoeae, or Chlamydia trachomatis, or both Neisseria gonorrhoeae and Chlamydia trachomatis, such as urethritis, an ocular infection, or a pharyngeal infection, using fusidic acid, or pharmaceutically acceptable salt thereof, are described.
US08247393B2 Conjugated estrogen compositions, applicators, kits, and methods of making and use thereof
The present invention is directed to monophasic pharmaceutical compositions comprising a conjugated estrogen and a hydrophilic or lipophilic excipient. The present invention is also directed to kits and applicators comprising the pharmaceutical compositions. The invention is also directed to methods for treating menopausal conditions in a female comprising administration of the pharmaceutical compositions.
US08247392B2 Materials for selective trapping of carbon monoxide
Compounds of formula (I) are disclosed. The tetrapyrole ring in formula (I) can be substituted with a metal cation (M); R1, R2, R3 and R4 separately represent a hydrogen atom, a C1-4 alkyl or alkyloxy radical, or a phenyl radical optionally substituted by vinyl, hydroxy, nitro, amino, bromo, chloro, fluoro, iodo, benzyloxy, or hydroxymethyl radicals; R5, R6, R7 and R8 separately represent a hydrogen atom or a C1-4 alkyl radical; Ra, Rb and Rc separately represent a hydrogen atom, a C1-4 alkyl or alkyloxy radical optionally substituted by a halogen, or a phenyl radical optionally substituted by vinyl, hydroxy, nitro, amino, bromo, chloro, fluoro, iodo, benzyloxy, or hydroxymethyl radicals, wherein at least one of Ra, Rb, and Rc is a phenyl radical. Compounds of formula (I) bound to a silica, a sol-gel material or a mesoporous silica are useful for selective trapping of carbon monoxide.
US08247391B2 Gel compositions
The present invention relates to a gel composition, comprising first and second gel-forming moieties which bind reversibly to one another to form a gel. The binding of the moieties is sensitive to the level of an analyte, and either or both of the gel-forming moieties are attached to cross-linked particulate entities such that the interstices between the entities allow gel-sol and sol-gel transformation, and yet are not so small that the analyte cannot diffuse therethrough. The invention also provides drug delivery systems and sensors for detecting an analyte utilizing such a gel.
US08247390B2 Modified hydrophilic polymers containing hydrophobic groups
Disclosed are hydrophilic polymers such as polysaccharides, including hyaluronic acid of any origin, modified by reaction with epoxy-functional-silicones. Hydrophobic silicon, which contains chemically active groups covalently attach to the backbone of the hydrophilic polymer and gives these new, modified polymers the ability to dissolve hydrophobic compounds including oils, drugs, and vitamins, while maintaining the hydrophilic properties and benefits of the unmodified polymer. With respect to topical applications these polymers substantially increase the stability of formulations and provide for ease of preparation. The properties and advantages of the original polymer are maintained while other properties are augmented, namely the ability to combine with or dissolve hydrophobic and hydrophilic drugs. The products can be used alone or in combination with other substances for various applications including cosmetic, medical, and drug delivery applications. Also disclosed are methods for preparing them.
US08247388B2 Role of miRNA in T cell leukemia
The ability of miR-181a to support active signaling between Notch and pre-TCR pathways by coordinately dampening negative regulators of these pathways allows the use of miR-181a as a therapeutic target for T-ALL.
US08247386B2 Methods and compositions for the treatment of eye disorders with increased intraocular pressure
The present invention relates to methods and compositions that decrease intraocular pressure (IOP) of the eye. The compositions of the invention comprise short interfering nucleic acid molecules (siNA) including, but not limited to, siRNA that decrease expression of genes associated with production or drainage of intraocular fluid. The compositions of the invention can be used in the preparation of a medicament for the treatment of an eye conditions displaying increased IOP such as glaucoma, infection, inflammation, uveitis, and diabetic retinopathy. The methods of the invention comprise the administration to a patient in need thereof an effective amount of one or more siNAs of the invention.
US08247383B2 Drug-carrier complexes and methods of use thereof
Drug-carrier complexes, drug carriers, pharmaceutical formulations, methods of delivery drugs to an organism or tissue culture, methods of increasing the solubility of a substance, targeted carriers, drug delivery systems and implants are described. The compositions and methods of the invention include forming complexes having reversible associations between nucleotides and drugs. The compositions and methods of the invention can be employed to target drugs to cells, organisms or combinations of cells to treat and to study the underlying mechanisms of diseases, and to test drug candidates.
US08247381B2 Branched water-soluble polymers and their conjugates
The present invention provides branched water-soluble polymers that allow two or more water-soluble polymers to be conjugated to another species. The branched polymers provide access to therapeutic agents that are conjugated at a single site to two or more water-soluble polymers. The branched polymers are based upon branch points that are simple branched alkyl structures, reactive side-chain amino acids and small peptides of reactive side-chain amino acids, and saccharides. Also provided is a method for preparing mono-disperse poly(ethylene glycol) of a well-defined and determinable molecular weight, and a method for the rational end-functionalization of poly(ethylene glycol). Conjugates of the branched water-soluble polymers with diverse species, e.g., peptides, lipids, glycolipids and small molecules are also provided.
US08247378B2 Homing peptide for tumor vasculature
This invention provides for a 9 mer peptide (CTPSPFSHC SEQ ID NO:1) that selectively binds to the tumor vasculature supporting tumors of the alimentary canal. The homing peptide has both diagnostic and therapeutic uses.
US08247377B2 Non-steroidal glucocorticoid inhibitors and their use in treating inflammation, allergy and auto-immune conditions
The present invention provides compounds of formula (I): a process for their preparation, to pharmaceutical compositions comprising the compounds and the preparation of said compositions, to intermediates and to use of the compounds for the manufacture of a medicament for therapeutic treatment, particularly for the treatment of inflammation, allergy and/or autoimmune conditions.
US08247372B2 Depsipeptides and their therapeutic use
Compounds which are Spiruchostatin analogues of the general formula (I) or (I′), isosteres thereof and pharmaceutically acceptable salts thereof are found to inhibit HDAC wherein R1, R2, R3 and R4 are the same or different and represent an amino acid side chain moiety and each R6 is the same or different and represents hydrogen or C1-C4 alkyl.
US08247369B2 Modified Cry3A toxins and nucleic acid sequences coding therefor
Methods for making a modified Cry3A toxin are disclosed. Such methods include the insertion of a protease recognition site that is recognized by a gut protease of a target insect, such as corn rootworm, into at least one position of a Cry3A toxin so that a modified Cry3A toxin is thus designed. The coding sequence of the modified Cry3A toxin may be transformed into a host cell and the host cell grown under conditions that allow the host cell to produce the modified Cry3A toxin. The host cell may be a plant cell and the plant may be comprised in a transgenic plant. Thus, the transgenic plant may be used to produce the modified Cry3A toxin.
US08247367B2 Binding agent for solidification matrix
Material, composition, and manufacturing method alternatives for a solidification matrix that may be used, for example, in solid cleaning compositions, or other technologies. In at least some embodiments, the solidification matrix includes a binding agent that is formed by the use of MGDA, or a salt or derivative thereof, and water to produce a solid binding agent. In some embodiments, the MGDA and water combines and can solidify to act as a binder material or binding agent dispersed throughout a solid composition that may contain other functional ingredients that provide the desired properties and/or functionality to the solid composition.
US08247363B2 MG++ chemistry and method for fouling inhibition in heat processing of liquid foods and industrial processes
The present invention relates to methods for removing or preventing scale formation in a liquid food processing operation. The present invention also relates to methods and compositions for increasing the solubility of insoluble calcium salts in an acidic environment. Aqueous antiscalant solutions comprising soluble magnesium salts are used to prevent the precipitation of insoluble calcium salts and/or to increase the solubility of insoluble calcium salts.
US08247361B2 Fluorine-based lubricant composition
A fluorine-based lubricant composition comprising a base oil and a fluorine-containing compound represented by the general formula: CF3(CF2)n O(CF2O)p(C2F4O)q(C3F6O)rRfCONHAr (wherein, Ar is a 2-benzimidazole group, Rf is a fluorocarbon group of carbon number of from 1 or 2, n is 0, 1 or 2, p, q and r are an integer satisfying the condition p+q+r≦100, where one or two of p, q and r may be 0, and the CF2O group, the CF2O4 group and the C3F6O group are the groups bound randomly in the main chain) as an additive containing in the base oil. The fluorine-based lubricant composition has an improved long term anti-rust property and thermal resistance property, and further the fluorine-based lubricant composition obtained by adding a thickening agent to the composition reduces abrasion of the sliding member such as electric contact having a noble metal surface including a gold or silver plating surface, a copper surface and a copper alloy surface.
US08247360B2 Heat treating oil composition
The present invention provides a refrigerating machine oil, a compressor oil composition, a hydraulic oil composition, a metalworking oil composition, a heat treating oil composition, a lubricating oil composition for machine tools and a lubricating oil composition which comprise a lubricating oil base oil having % CA of not more than 2, % CP/% CN of not less than 6 and an iodine value of not more than 2.5.
US08247359B2 Water-in-oil emulsions, methods and uses of emulsifying agents
In one aspect, the present invention provides a water-in-oil emulsion comprising from about 5 to about 40 wt % aqueous phase and from about 95 to about 60 wt % non-aqueous phase, said aqueous phase being dispersed in said non-aqueous phase in the form of droplets having an average droplet size no greater than about 0.1 μm, said emulsion comprising: at least 60 wt % of an oil selected from fuel oils, lubricating oils and mixtures thereof, from about 1 to about 30 wt % of emulsifying agents, and the balance to 100 wt % water, wherein said emulsifying agents include a fatty (C8-C24)-amido-(C1-C6)alkyl betaine, is useful as a fuel, coolant or lubricant. In another aspect the present invention provides one or more stable, clear, water-in-fuel microemulsion-forming surfactants may be used in a liquid fuel or oil which is immiscible with water to: a) scavenge free-water which exists in or is introduced into the liquid fuel or oil thereby to render or retain the liquid fuel or oil in a usable state; and/or b) inhibit the growth of aquatic micro-organisms in the liquid fuel or oil when the fuel or oil becomes contaminated with free-water thereby to retain the liquid fuel or oil in a usable state.
US08247356B2 Zirconium-based cross-linking composition for use with high pH polymer solutions
A cross-linking composition comprising (a) an aqueous liquid; (b) a pH buffer; (c) a cross-linkable organic polymer; and (d) a solution of a zirconium cross-linking agent comprising the product of contacting a zirconium complex with an alkanolamine and ethylene glycol wherein the mole ratio of alkanolamine to zirconium is 2:1 to 4:1 and the mole ratio of ethylene glycol to zirconium is 1:1 to 10:1. Optionally, water, hydroxyalkylated ethylenediamine, or both are added to the zirconium complex. The cross-linking composition of this invention is useful in oil field applications, for example, for hydraulically fracturing a subterranean formation and for plugging permeable zones or leaks in a subterranean formation.
US08247354B2 Fault current limiter with a plurality of superconducting elements connected in a ring-shaped fashion
A fault current limiter and a method for the production thereof has a superconducting device (1; 21; 31; 41; 51; 61; 71; 72) comprising a sequence of superconducting elements (2a-2f), each with an electrically conducting substrate (3a-3d), a superconducting film (5a-5d) and an electrically insulating intermediate layer (4a-4c) provided between the substrate and the superconducting film. The superconducting films (5a-5d) of adjacent superconducting elements (2a-2f) of the sequence are electrically connected, in particular in series, wherein the electrically conducting substrate (3a-3d) of each superconducting element (2a-2f) of the sequence is electrically insulated from each electrically conducting substrate (3a-3d) of those adjacent superconducting elements (2a-2f) within the sequence whose superconducting films (5a-5d) are electrically connected in series with the superconducting film (5a-5d) of said superconducting element (2a-2f). The superconducting elements (2a-2f) are connected in a ring shaped fashion.
US08247353B2 Comb polymer derivatives of polyetheramines useful as agricultural dispersants
This invention concerns novel dispersants that are the reaction products of succinic anhydride-containing resins with certain amines. These water soluble dispersants have been found to be unique and highly effective dispersants for water insoluble agricultural suspension concentrate formulations.
US08247352B2 Method of inhibiting ethylene production in plants
Methods of inhibiting ethylene production in a plant are provided that involve contacting a plant or plant part with an inhibitor of 1-aminocyclopropane-1-carboxylic acid oxidase (ACCO). The methods can be used to delay fruit and vegetable ripening, flower opening, or senescence of cut flowers. Also described are kits including an ACCO inhibitor and a floral preservative.
US08247351B2 Insecticidal compositions having improved effect
The present invention concerns boosting the activity of crop protection materials comprising active ingredients from the class of the phenyl-substituted cyclic ketoenols through the addition of ammonium salts and/or phosphonium salts or through the addition of ammonium salts and/or phosphonium salts and penetrants, the corresponding materials, processes for preparing them, and their use in crop protection.
US08247348B1 Method of preserving cut plant material
The present invention is directed to a composition of matter to be applied to a carved pumpkin, more commonly called a jack o'lantern, in order to retard environmental degradation thereof, and to repel insects. The composition consists of an aqueous solution containing an antiseptic, a fungicide, an insecticide and a desiccant. The carved pumpkin is totally immersed in the aqueous solution to create a hyperosmotic condition to allow the preservative solution to permeate the fibers of the carved pumpkin, and at the same time replacing moisture from within the carved pumpkin with a mineral, to retain the original shape and structural stability of the carved pumpkin. The composition may also contain a buffer to maintain a pH level above 8.0. The present invention also provides a method of protecting a carved pumpkin using a composition according to the present invention.
US08247346B2 Dry scrubbing air filtration media
A solid air filtration medium includes an impregnate with an organic amine and an inorganic metal salt. The medium has from about 0.1 to about 25% by weight of impregnate. The impregnate contains from about 0.1 to about 5% by weight organic amine, and the organic amine includes aqueous urea, solid urea, melamine or mixtures thereof. The impregnate contains from about 0.1 to about 5% by weight metal salt, and the metal salt includes magnesium oxide, calcium oxide or mixtures thereof. The impregnate optionally further includes a surfactant such as polyacrylic acid. Methods for forming a solid air filtration medium having an impregnate containing an organic amine and an inorganic metal salt and methods for removing contaminants from a fluid stream are also provided.
US08247344B2 Multi-metal oxide catalyst and method for producing (meth)acrylic acid by using the same
The present invention provides a Mo—Bi—Nb based composite metal oxide (with the proviso that Te is not included); a method for producing (meth)acrylic acid from at least one reactant selected from the group consisting of propylene, propane, isobutylene, t-butyl alcohol and methyl-t-butyl ether, in which a Mo—Bi—Nb based composite metal oxide (with the proviso that Te is not included) is used as a catalyst; and a reactor used for producing (meth)acrylic acid from at least one reactant selected from the group consisting of propylene, propane, isobutylene, t-butyl alcohol and methyl-t-butyl ether, in which a Mo—Bi—Nb based composite metal oxide (with the proviso that Te is not included) is used as a catalyst. Further, the present invention provides a method for producing the (meth)acrylic acid without any additional process of converting (meth)acrolein into (meth)acrylic acid.
US08247343B2 Stable sub-micron titania sols
The present invention is directed to compositions and processes for the production of stable, alkaline, high solids, low viscosity, low surface tension, low flammability, sub-micron titania sols that have minimal offensive odor and methods of their use. Compositions of the present invention include, for example, mixtures of strong and weak organic bases used as dispersants to stabilize the titania sols. The dispersant mixtures have been found to result in relatively high titania solids content, low surface tension, low viscosity suspensions that are low in flammability. Sols produced according to the present invention can be used, for example, in catalytic applications such as catalyst supports for diesel emission control, or in pollutant photocatalyst applications in which it is desirable to have the titania in sol form.
US08247342B2 Polymer supported chrome catalyst for olefins polymerization
A highly active supported chromium catalyst composition for ethylene and other olefins polymerization and also for ethylene copolymerization with efficient incorporation of comonomer, produces polymers with superior spherical morphology, improved bulk density and almost 0% fines. The catalyst composition component includes at least one chromium compound, mainly chromium acetylacetonate, or chromium hexaflouroacetonylacetonate, or chromium diethylmalonate. One magnesium compound, or aluminum compound, metal alkoxy compound and defined polymer particles mainly chloromethylated cross linked styrene-DVB copolymer or polyvinylchloride. The catalyst composition, when used in conjunction with an organoaluminum compound or a mixture of organoaluminum compounds, can be used for olefin polymerization to produce medium or high density polyethylene and copolymers of ethylene with alpha-olefins having about 3 to 18 carbon atoms.
US08247341B2 Procatalyst composition with silyl glutarate and method
Disclosed are procatalyst compositions having an internal electron donor which includes a silyl glutarate and optionally an electron donor component. Ziegler-Natta catalyst compositions containing the present procatalyst compositions exhibit strong activity and produce propylene-based olefins with high isotacticity.
US08247335B2 Water-dispersible and multicomponent fibers from sulfopolyesters
Disclosed are water-dispersible fibers derived from sulfopolyesters having a Tg of at least 25° C. The fibers may contain a single sulfopolyester or a blend of a sulfopolyester with a water-dispersible or water-nondispersible polymer. Also disclosed are multicomponent fibers comprising a water dispersible sulfopolyester having a Tg of at least 57° C. and a water non-dispersible polymer. The multicomponent fibers may be used to produce microdenier fibers. Fibrous articles may be produced from the water-dispersible fibers, multicomponent fibers, and microdenier fibers. The fibrous articles include water-dispersible and microdenier nonwoven webs, fabrics, and multilayered articles such as wipes, gauze, tissue, diapers, panty liners, sanitary napkins, bandages, and surgical dressings. Also disclosed is a process for water-dispersible fibers, nonwoven fabrics, and microdenier webs. The fibers and fibrous articles have further applications in flushable personal care and cleaning products, disposable protective outerwear, and laminating binders.
US08247327B2 Methods and compositions for polishing silicon-containing substrates
The invention provides chemical-mechanical polishing (CMP) compositions and methods for polishing a silicon-containing substrate. A method of the invention comprises the steps of contacting a silicon-containing substrate with a polishing pad and an aqueous CMP composition, and causing relative motion between the polishing pad and the substrate while maintaining a portion of the CMP composition in contact with the surface of the substrate to abrade at least a portion of the substrate. The CMP composition comprises a ceria abrasive, a polishing additive bearing a functional group with a pKa of about 4 to about 9, a nonionic surfactant with an hydrophilic portion and a lipophilic portion wherein the hydrophilic portion has a number average molecular weight of about 500 g/mol or higher, and an aqueous carrier, wherein the pH of the composition is 7 or less. The method reduces defects on the wafers, particularly local areas of high removal. The method is also useful for polishing dielectric silicon-containing substrates at a high rate relative to semiconductor silicon-containing substrates.
US08247326B2 Method of polishing nickel-phosphorous
The invention is directed to a method of chemically-mechanically polishing a surface of a substrate, comprising contacting a surface of a substrate comprising nickel-phosphorous with a chemical-mechanical polishing composition comprising wet-process silica, an agent that oxidizes nickel-phosphorous, and an aminopolycarboxylic acid, wherein the polishing composition has a pH of about 1 to about 5, and abrading at least a portion of the nickel-phosphorous to polish the substrate.
US08247324B2 Semiconductor device with buried gate and method for fabricating the same
A method for fabricating a semiconductor device includes forming landing plugs over a substrate, forming a trench by etching the substrate between the landing plugs, forming a buried gate to partially fill the trench, forming a gap-fill layer to gap-fill an upper side of the buried gate, forming protruding portions of the landing plugs, and trimming the protruding portions of the landing plugs.
US08247322B2 Via/contact and damascene structures and manufacturing methods thereof
A method for forming a semiconductor structure includes forming a dielectric layer over a substrate. A first non-conductive barrier layer is formed over the dielectric layer. At least one opening is formed through the first non-conductive barrier layer and within the dielectric layer. A second non-conductive barrier layer is formed over the first non-conductive barrier layer and within the opening. At least a portion of the second non-conductive barrier layer is removed, thereby at least partially exposing a top surface of the first non-conductive barrier layer and a bottom surface of the opening, with the second non-conductive barrier layer remaining on sidewalls of the opening. A seed layer and conductive layer is then formed and a single polishing operation removes the seed layer and conductive layer.
US08247315B2 Plasma processing apparatus and method for manufacturing semiconductor device
By an evacuation unit including first and second turbo molecular pumps connected in series, the ultimate pressure in a reaction chamber is reduced to ultra-high vacuum. By a knife-edge-type metal-seal flange, the amount of leakage in the reaction chamber is reduced. A microcrystalline semiconductor film and an amorphous semiconductor film are stacked in the same reaction chamber where the pressure is reduced to ultra-high vacuum. By forming the amorphous semiconductor film covering the surface of the microcrystalline semiconductor film, oxidation of the microcrystalline semiconductor film is prevented.
US08247312B2 Methods for printing an ink on a textured wafer surface
A method of printing an ink on a wafer surface configured with a set of non-rounded peaks and a set of non-rounded valleys is disclosed. The method includes exposing the wafer including at least some non-rounded peaks and at least some of the non-rounded valleys in a region to an etchant. The method further includes depositing the ink on the region, wherein a set of rounded peaks and a set of rounded valleys are formed.
US08247309B2 Controlled temperature implantation
In order to reduce and render uniform the surface roughness and variations in thickness of a layer after detachment (post-fracture) of a donor substrate, the mean temperature of the donor substrate during implantation thereof is controlled so as to be in the range 20° C. to 150° C. with a maximum temperature variation of less than 30° C.
US08247308B2 Method for manufacturing SOI substrate
It is an object of the preset invention to increase adhesiveness of a semiconductor layer and a base substrate and to reduce defective bonding. An oxide film is formed on a semiconductor substrate and the semiconductor substrate is irradiated with accelerated ions through the oxide film, whereby an embrittled region is formed at a predetermined depth from a surface of the semiconductor substrate. Plasma treatment is performed on the oxide film on the semiconductor substrate and the base substrate by applying a bias voltage, the surface of the semiconductor substrate and a surface of the base substrate are disposed opposite to each other, a surface of the oxide film is bonded to the surface of the base substrate, heat treatment is performed after the surface of the oxide film is bonded to the surface of the base substrate, and separation is caused along the embrittled region, whereby a semiconductor layer is formed over the base substrate with the oxide film interposed therebetween.
US08247305B2 Method and resulting structure for deep trench polysilicon hard mask removal
A method of forming a capacitor structure includes forming a pad oxide layer overlying a substrate, a nitride layer overlying the pad oxide layer, an interlayer dielectric layer overlying the nitride layer, and a patterned polysilicon mask layer overlying the interlayer dielectric layer. The method then applies a first RIE process to form a trench region through a portion of the interlayer dielectric layer using the patterned polysilicon mask layer and maintaining the first RIE to etch through a portion of the nitride layer and through a portion of the pad oxide layer. The method stops the first RIE when a portion of the substrate has been exposed. The method then forms an oxide layer overlying the exposed portion of the substrate and applies a second RIE process to continue to form the trench region by removing the oxide layer and removing a portion of the substrate to a predetermined depth.
US08247301B2 Substrate and manufacturing method therefor
A substrate having, on a base material, a barrier film for preventing copper diffusion containing one or more metal elements selected from tungsten, molybdenum and niobium, a metal element having a catalytic function in electroless plating such as ruthenium, rhodium, and iridium, and nitrogen contained in the form of a nitride of the aforementioned one or more metal elements selected from tungsten, molybdenum and niobium. The barrier film for preventing copper diffusion is manufactured by sputtering in a nitrogen atmosphere using a target containing one or more metal elements selected from tungsten, molybdenum and niobium and the aforementioned metal element having a catalytic function in electroless plating.
US08247297B2 Method of filling large deep trench with high quality oxide for semiconductor devices
A method is disclosed for creating a semiconductor device structure with an oxide-filled large deep trench (OFLDT) portion having trench size TCS and trench depth TCD. A bulk semiconductor layer (BSL) is provided with a thickness BSLT>TCD. A large trench top area (LTTA) is mapped out atop BSL with its geometry equal to OFLDT. The LTTA is partitioned into interspersed, complementary interim areas ITA-A and ITA-B. Numerous interim vertical trenches of depth TCD are created into the top BSL surface by removing bulk semiconductor materials corresponding to ITA-B. The remaining bulk semiconductor materials corresponding to ITA-A are converted into oxide. If any residual space is still left between the so-converted ITA-A, the residual space is filled up with oxide deposition. Importantly, the geometry of all ITA-A and ITA-B should be configured simple and small enough to facilitate fast and efficient processes of oxide conversion and oxide filling.
US08247292B2 Nonvolative memory device using semiconductor nanocrystals and method of forming same
A method of making a uniform nanoparticle array, including performing diblock copolymer thin film self assembly over a first dielectric on silicon, creating a porous polymer film, transferring a pattern into the first dielectric, selectively growing epitaxial silicon off a silicon substrate from within pores to create a silicon nanoparticle array.
US08247289B2 Capacitor and manufacturing method thereof
A capacitor having a high quality and a manufacturing method of the same are provided.A capacitor has a lower electrode formed on an oxide film, a dielectric layer formed on the lower electrode, an upper electrode formed so as to face the lower electrode with the dielectric layer between, and an upper electrode formed so as to cover the upper electrode, an opening portion of the upper electrode and an opening portion of the dielectric layer. By forming the upper electrode on the dielectric layer, it is possible to pattern the dielectric layer by using the upper electrode as a mask, and provide a capacitor having a high-quality dielectric layer by preventing impurity diffusion into the dielectric layer. By forming the upper electrode on the dielectric layer, it is possible to prevent the dielectric layer from being exposed to etching liquid, liquid developer, etc.
US08247286B2 Semiconductor device having transistor and method of manufacturing the same
One embodiment of inventive concepts exemplarily described herein may be generally characterized as a semiconductor device including an isolation region within a substrate. The isolation region may define an active region. The active region may include an edge portion that is adjacent to an interface of the isolation region and the active region and a center region that is surrounded by the edge portion. The semiconductor device may further include a gate electrode on the active region and the isolation region. The gate electrode may include a center gate portion overlapping a center portion of the active region, an edge gate portion overlapping the edge portion of the active region, and a first impurity region of a first conductivity type within the center gate portion and outside the edge portion. The semiconductor device may further include a gate insulating layer disposed between the active region and the gate electrode.
US08247285B2 N-FET with a highly doped source/drain and strain booster
A structure and method of making an N-FET with a highly doped source/drain and strain booster are presented. The method provides a substrate with a Ge channel region. A gate dielectric is formed over the Ge channel and a gate electrode is formed over the gate dielectric. Sacrificial gate spacers are disposed on the sidewalls of the gate dielectric and gate electrode. Cavities are etched into the substrate extending under the sacrificial gate spacers. Si1-xGex source/drain regions are doped in-situ during formation, x<0.85.
US08247279B2 Method of fabricating semiconductor device using epitaxial growth inhibiting layers
A semiconductor device according to one embodiment includes: a first transistor comprising a first gate electrode formed on a semiconductor substrate via a first gate insulating film, a first channel region formed in the substrate under the first film, and first epitaxial crystal layers formed on both sides of the first channel region in the substrate, the first layers comprising a first crystal; and a second transistor comprising a second gate electrode formed on the substrate via a second gate insulating film, a second channel region formed in the substrate under the second film, second epitaxial crystal layers formed on both sides of the second channel region in the substrate, and third epitaxial crystal layers formed on the second layers, the second layers comprising a second crystal, the third layers comprising the first crystal, the second transistor having a conductivity type different from that of the first transistor.
US08247278B2 Method for manufacturing semiconductor device
The present application discloses a method for manufacturing a semiconductor device, comprising the steps of: forming a semiconductor substrate, a gate stack and a second protection layer in sequence on a first insulating layer; after defining a gate region and removing portions of the second protection layer and the gate stack outside the gate region, while keeping portions of the stop layer, the semiconductor layer and the second insulating layer which covers sidewalls of the patterned semiconductor layer outside the gate region and exposing the sacrificial layer, performing source/drain ion implementation in the semiconductor layer; after forming a second sidewall spacer so as to cover at least the exposed portion of the sacrificial layer, removing the first protection layer and the second protection layer so as to expose the semiconductor layer and the gate stack; and forming a contact layer on the exposed portion of the semiconductor layer and the gate stack; performing planarization so as to expose the first protection layer, and then removing the first protection layer, the sacrificial layer, the stop layer and the semiconductor layer with the first sidewall spacer and the second sidewall spacer as a mask, so as to form a cavity which exposes the first insulating layer. It facilitates reduction of short channel effects, resistance of source/drain regions, and parasite capacitance.
US08247276B2 Thin film transistor, method for manufacturing the same, and semiconductor device
In a thin film transistor, an increase in off current or negative shift of the threshold voltage is prevented. In the thin film transistor, a buffer layer is provided between an oxide semiconductor layer and each of a source electrode layer and a drain electrode layer. The buffer layer includes a metal oxide layer which is an insulator or a semiconductor over a middle portion of the oxide semiconductor layer. The metal oxide layer functions as a protective layer for suppressing incorporation of impurities into the oxide semiconductor layer. Therefore, in the thin film transistor, an increase in off current or negative shift of the threshold voltage can be prevented.
US08247274B2 Organic light-emitting display apparatus and method of manufacturing the same
A method of manufacturing an organic light-emitting display apparatus contemplates preparing a first substrate, preparing a second substrate, forming a first sealant and a second sealant on the second substrate, the first sealant having a height different from a height of the second sealant, injecting a filling material into a space surrounded by the first sealant and the second sealant, adhering the first substrate to the second substrate, and radiating an energy beam onto at least one of the first sealant and the second sealant.
US08247267B2 Wafer level IC assembly method
A wafer level integrated circuit assembly method is conducted as follows. First, a mother device wafer with plural first posts is provided. The first posts are used for electrical connection and are made of copper according to an embodiment. Solder is sequentially formed on the first posts. The solder is preferably pre-formed on a wafer, and the locations of the solder correspond to the first posts of the mother device wafer. Consequently, the solder can be formed on or adhered to the first posts by placing the wafer having pre-formed solder onto the first posts. Plural dies having plural second posts corresponding to the first posts are placed onto the mother device wafer. Then, the solder is reflowed to bond the first and second posts, and the mother device wafer is diced.
US08247263B2 Method for producing an optical, radiation-emitting component and optical, radiation-emitting component
The invention relates to a method for producing an optical and a radiation-emitting component by a molding process, and to an optical and a radiation-emitting component having well-defined viscosity.
US08247256B2 Method of fabricating a complementary metal oxide semiconductor (CMOS) image sensor
There are provided a CMOS image sensor and a method for fabrication thereof. The CMOS image sensor having a reset transistor, a select transistor, a drive transistor and a photodiode, includes an active region in shape of a line, a gate electrode of the drive transistor, which is intersected with the active region, a blocking layer interposed between the active region and the gate electrode in which the blocking layer is formed on an intersection region of the active region and the gate electrode, and a metal contact electrically connected to the gate electrode, wherein the metal contact is not electrically connected to the active region by the blocking layer.
US08247255B2 Modular system and process for continuous deposition of a thin film layer on a substrate
A process and associated system for vapor deposition of a thin film layer on a photovoltaic (PV) module substrate is includes establishing a vacuum chamber and introducing the substrates individually into the vacuum chamber. The substrates are pre-heated as they are conveyed through the vacuum chamber, and are then conveyed in serial arrangement through a vapor deposition apparatus in the vacuum chamber wherein a thin film of a sublimed source material is deposited onto an upper surface of the substrates. The substrates are conveyed through the vapor deposition apparatus at a controlled constant linear speed such that leading and trailing sections of the substrate in a conveyance direction are exposed to the same vapor deposition conditions within the vapor deposition apparatus. The vapor deposition apparatus may be supplied with source material in a manner so as not to interrupt the vapor deposition process or non-stop conveyance of the substrates through the vapor deposition apparatus.
US08247253B2 MEMS package structure and method for fabricating the same
A method for fabricating MEMS package structure includes the following steps. Firstly, a substrate is provided. Next, a plurality of lower metallic layers and first oxide layers are formed to compose a MEMS structure and an interconnecting structure. Next, an upper metallic layer is formed on the MEMS structure and the interconnecting structure. The upper metallic layer has a first opening and a second opening. Next, the first opening and the second opening are employed as etching channels to remove a portion of the first oxide layers so as to form a first cavity surrounding the MEMS structure and form a second cavity above the interconnecting structure. The first cavity communicates with the second cavity. Next, the second opening is sealed in a vacuum environment. Next, a packaging element is formed on the upper metallic layer in a non-vacuum environment to seal the first opening.
US08247252B2 High power top emitting vertical cavity surface emitting laser
A method of adjusting a power density in a laser device including a VCSEL array providing an increased power density at a high wall-plug efficiency in that the lateral design parameters are appropriately selected on the basis of a relationship that has been established for a specified vertical design, a corresponding process technology and specified operating conditions. Thus, the total output power, the power density, and the efficiency may be optimized independently from other design criteria and application requirements by tuning only the lateral size of the individual VCSEL elements and the pitch of nearest neighbors of the elements within the array. Hence, for a lateral size of less than 30 μm and a pitch of less than 80 μm, a highly efficient VCSEL array can be provided with a high power density, thereby optimizing manufacturing costs for the output power per chip area.
US08247251B2 Method of fabricating light-emitting element
A method of fabricating a light-emitting element, in which less stress is applied to the light-emitting element, includes: forming element isolation patterns on a substrate; forming a buffer layer on an entire surface of the substrate to directly contact the surface of the substrate and the element isolation patterns and forming light-emitting structure layers on the buffer layer; forming element isolation trenches, which overlap at least part of the element isolation patterns, respectively, buffer layer patterns and light-emitting structures which are separated from each other by the element isolation trenches, respectively, by etching the buffer layer and the light-emitting structure layers; injecting a lift-off solution into the element isolation trenches to remove the element isolation patterns; and removing the substrate.
US08247248B2 Methods and apparatus for forming uniform layers of phosphor material on an LED encapsulation structure
A method for forming a layer of phosphor material on an LED encapsulant structure includes forming a layer of a phosphor material on a first surface, disposing the first surface to cause the phosphor material to be in contact with a surface of the LED encapsulant structure, applying a pressure between the first surface and the surface of the LED encapsulant structure, and causing the layer of the phosphor material to be attached to the LED encapsulant structure.
US08247245B2 Pixel structure and method for fabricating the same
A pixel structure is disclosed. The pixel structure includes a substrate, a first data line having at least one end formed on the substrate, a first insulation layer overlying the first data line and exposing a part of the end of the first data line, a shielding electrode disposed on the first insulation layer and overlapped with the first data line, a second data line formed on the first insulation layer and electrically connected to the exposed end of the first data line, a second insulation layer overlying the shielding electrode and the second data line, and a pixel electrode formed on the second insulation layer and overlapped with the shielding electrode. The invention also provides a method for fabricating the pixel structure.
US08247241B2 Method for detecting target compound
According to an aspect of the invention, there is provided a method for detecting a target compound including: injecting a test liquid containing a target compound into a colloid solution of magnetic nano-particles having an average particle diameter of 50 nm or less to allow the target compound to bind to the magnetic nano-particles, thereby forming bound magnetic nano-particles having a diameter of 100 nm or more; and bringing a dispersion liquid containing the bound magnetic nano-particles in proximity to a magnetic sensor including at least a magnetoresistive (MR) element and a permanent magnet while measuring the change in magnetic resistance to selectively detect the bound magnetic nano-particles, thereby indirectly detecting the target compound.
US08247240B2 Method and apparatus for biosensor spectral shift detection
Performing high-resolution determination of the relative shift of the spectral properties of a biosensor. The shift in the resonance peak of the biosensor is indicative of the amount of material bound to the surface of the biosensor. A preferred biosensor is a Guided Mode Resonant Filter Biosensor (GMRFB). In one aspect of the invention, curve fitting is used to determine the relative location of the spectrum of the unexposed biosensor with respect to those spectra that are altered (e.g., shifted) by the presence of materials bound to the surface of the biosensor. In an alternative embodiment, the cross correlation function is used to detect spectral peak offsets between a reference spectrum and a spectrum measured from an exposed biosensor. In yet another alternative, maximal likelihood estimation techniques are used to determine the spectral shift or offs.
US08247234B2 Isotopically labeled compositions and method
Compounds having stable isotopes 13C and/or 2H were synthesized from precursor compositions having solid phase supports or affinity tags.
US08247233B2 Integrated fluid analyte meter system
An integrated meter system for determining information related to an analyte of a fluid sample includes a meter including a housing and a plurality of test sensors. Each of the plurality of test sensors includes a penetrating member, a testing portion, and a channel. The channel is adapted to receive the fluid sample. The test sensors are removably located within the housing. At least one of the test sensors is removably connected to an adjacent test sensor. The integrated meter system also includes a test-sensor advancement mechanism that is configured to advance the test sensors.
US08247231B2 Methods and compositions for producing antigenic responses
The present invention relates to methods of producing an antigenic response in which an antigen is contacted to an antigen-presenting cell, wherein the improvement comprises contacting the antigen-presenting cell with an A1 adenosine receptor activating agent in an amount sufficient to increase the antigenic response of the antigen-presenting cell to the antigen. The present invention further provides methods, compositions, combination therapies, imaging techniques, and diagnostic kits that may improve the diagnosis, prognosis, and/or survival of cancer patients, pathogen-infected patients, and infectious or non-infectious immune-deficient patients.
US08247227B2 Dendritic cell precursors
A method of generating a population of dendritic cell (DC) precursors includes obtaining a population of progenitor cells from a subject and culturing the progenitor cells in a culture medium. The culture medium can include Flt3 ligand and interleukin-6 and be free of granulocyte-macrophage colony-stimulating factor.
US08247226B2 Methods of evaluating an immune response to an antigen
The present invention incorporates germinal centers (GCs) into three-dimensional (3D) engineered tissue constructs (ETCs). In an embodiment, we have incorporated the GC in the design of an artificial immune system (AIS) to examine immune responses to vaccines and other compounds. Development of an in vitro GC adds functionality to an AIS, in that it enables generation of an in vitro human humoral response by human B lymphocytes that is accurate and reproducible, without using human subjects. The invention also permits evaluation of, for example, vaccines, allergens, and immunogens, and activation of human B cells specific for a given antigen, which can then be used to generate human antibodies. In an embodiment of the present invention the function of the in vitro GC is enhanced by placing FDCs and other immune cells in a 3D ETC; FDCs appear more effective over a longer time (antibody production is sustained for up to about 14 days.
US08247223B1 Method for catalytic treatment of a media
The methods are disclosed to introduce catalysts and fluids into an apparatus and/or media to effect remediation of contaminants, improve soil fertility and permeability, control undesirable pests, or create useful chemicals or food. Aerobic metabolism of compounds in a media is facilitated through the transfer of fluids, such as air. The apparatus and methods provide an environment for select organisms, including refugia and nutrient substrate. The biodegradable composition of the apparatus is partially transformed by catalytic treatment. Catalysts or remediation agents are produced in-situ, for specific applications that provide a range of retention, activation, activity, and release profiles.
US08247222B2 Micro-chamber processing apparatus for cell culture and method
This invention relates to a method and apparatus for processing cell cultures. The apparatus comprises a micro-chamber comprising no more than one absorption layer and at least one gel layer, in this order, laminated on a transparent base plate having no conspicuous absorbency in visible and infrared regions, and at least one light source, the absorption layer having absorbency in visible and infrared regions, and the gel-like material being a substance which has a gel dissolution temperature of 100 degree C. or less, solates when heated and is in a gel state at room temperature and has absorbency for a specific wave length of visible and infrared regions, and the light source having a monochromatic light in the specific wave length, wherein the light source is disposed such that it irradiates on the absorption layer and/or the gel layer, with the exception that when no absorption layer is provided, at least two layers each composed of a gel-like material are laminated on the transparent base plate.
US08247221B2 Sample block apparatus and method for maintaining a microcard on sample block
A thermal cycling device for thermally cycling samples of biological material contained in a microcard having a top and bottom surface. The thermal cycling device can include a sample block having an upper surface configured for engaging the bottom surface of a microcard, a vacuum device, and a temperature control system operatively connected with the sample block. The upper surface of the sample block may include a plurality of channels, the channels defining spaces between the sample block and the bottom surface of a microcard that may be positioned thereon. The vacuum device may be in fluid communication with the sample block for drawing gas out of the spaces defined by the channels in the sample block. The vacuum device may be configured for substantially maintaining a vacuum between the sample block and microcard so that a retention force is imparted on the microcard to urge the microcard toward the sample block. Methods of maintaining a microcard on a sample block of a thermal cycling device are also provided.
US08247218B2 Extracellular potential sensing element, device for measuring extracellular potential, apparatus for measuring extracellular potential and method of measuring extracellular potential by using the same
A sensing element for measuring extracellular potential including a substrate, a well provided in a substrate, a guide section provided on the wall of the well, and a detective electrode formed at a lower surface of the substrate. The guide section is for guiding drug. The well is provided at the bottom with a depression, and a first throughhole penetrating through the depression and the lower surface of the substrate. The well is for mixing a subject cell, a culture solution and the drug together. The above-configured sensing element accurately measures a change generated by a subject cell.
US08247216B2 Ultra-high multiplex analytical systems and methods
Apparatus, systems and methods for use in analyzing discrete reactions at ultra high multiplex with reduced optical noise, and increased system flexibility. Apparatus include substrates having integrated optical components that increase multiplex capability by one or more of increasing density of reaction regions, improving transmission of light to or collection of light from discrete reactions regions. Integrated optical components include reflective optical elements which re-direct illumination light and light emitted from the discrete regions to more efficiently collect emitted light. Particularly preferred applications include single molecule reaction analysis, such as polymerase mediated template dependent nucleic acid synthesis and sequence determination.
US08247210B2 Host cells comprising alpha 1,2 mannosidase and culture methods thereof
Improved host cells and culture methods involving overexpression of MAN1C1 activity to improve protein production are provided.
US08247208B2 Zymomonas with improved xylose utilization in stress conditions
Strains of xylose utilizing Zymomonas with improved xylose utilization and ethanol production during fermentation in stress conditions were obtained using an adaptation method. The adaptation involved continuously growing xylose utilizing Zymomonas in media containing high sugars, acetic acid, ammonia, and ethanol.
US08247206B2 Fusion protein comprising an Escherichia coli chaperone protein and a human chaperone protein
The invention discloses the cloning, expression and uses of a chimeric fusion protein with superior chaperone and folding activities compared to the wild type chaperones. This invention relates to a chimeric fusion protein encoded by a recombinant DNA molecule containing nucleotide sequences coding for a polypeptide binding segment of a non-human chaperone protein and nucleotide sequences coding for an FK506 binding protein (FKBP) or an FK506-binding-protein-like domain (FKBP-like domain). In particular, this invention relates to a chimeric fusion protein encoded by a recombinant DNA molecule containing nucleotide sequences coding for a polypeptide binding segment of a non-human chaperone protein and nucleotide sequences coding for a human FKBP type peptidyl-prolyl-cis/trans isomerase (PPIase), methods of producing these chimeric fusion proteins and their uses as folding helpers in the production of other proteins and in the process of the production of vaccines or pharmaceuticals, and as folding helpers for performing immunoassays.
US08247203B2 Recovery of inorganic salt during processing of lignocellulosic feedstocks
A method for recovering inorganic salt during processing of a lignocellulosic feedstock is provided. The method comprises pretreating the lignocellulosic feedstock by adding an acid to the feedstock to produce a pretreated lignocellulosic feedstock. A soluble base is then added to the pretreated lignocellulosic feedstock to adjust the pH and produce a neutralized feedstock. The neutralized feedstock is then enzymatically hydrolyzed to produce an enzyme hydrolyzed feedstock and a sugar stream. Inorganic salt is recovered from either a stream obtained from the lignocellulosic feedstock prior to the step of pretreating, a stream obtained from the pretreated lignocellulosic feedstock, a stream obtained from the neutralized feedstock, a stream obtained from the sugar stream, or a combination of these streams. The inorganic salt may be concentrated, clarified, recovered and purified by crystallization, electrodialysis drying, or agglomeration and granulation, and then used as desired, for example as a fertilizer.
US08247200B2 Method of obtaining inorganic salt and acetate salt from cellulosic biomass
A process for obtaining inorganic salt and acetate salt from cellulosic biomass is disclosed. The cellulosic biomass is pretreated by adding one or more than one acid or base to produce a pretreated cellulosic biomass comprising acetic acid or acetate salt. One or more than one base or acid is then added to the pretreated cellulosic biomass to adjust the pretreated cellulosic biomass to a pH of about 4.0 to about 6.0 to produce a neutralized cellulosic biomass comprising inorganic salt and acetate salt. The neutralized biomass is then hydrolyzed by cellulase enzymes to produce a sugar stream. Streams arising from the processing of the cellulosic biomass to sugar are subjected to ion exclusion chromatography performed at pH 5.0 to about 10.0 to produce a stream comprising an inorganic salt and an acetate salt.
US08247199B2 Process for preparing glycerol esters
There is provided a process for the preparation of a compound including the step of interesterifying in the presence of an enzyme catalyst (a) a first triglyceride compound and (b) a second triglyceride compound.
US08247197B2 Method of detecting target molecule by using aptamer
An aptamer-probe complex for detecting the presence of a target molecule is disclosed. The complex of the present invention contains an aptamer moiety which is able to bind to an indicator protein and change the properties of the indicator protein, and a probe moiety which is able to bind to a target molecule, wherein the aptamer moiety and the probe moiety are combined in such a manner that the binding mode between the aptamer moiety and the indicator protein changes when the probe moiety binds to the target molecule. A target molecule can be detected with combination of an aptamer which binds to a certain protein, and a probe which binds to the target molecule, utilizing the properties of that protein as an indicator.
US08247196B2 Real-time PCR of targets on a micro-array
The present invention relates to a method and apparatus for monitoring on a micro-array a PCR amplification of a nucleotide molecule being present in a solution. The method includes the steps of: providing a support having fixed upon its surface a microarray having at least a capture molecule being immobilized in specifically localized areas of the support and a reaction chamber; introducing a solution containing the nucleotide molecule into the reaction chamber and reagents for nucleotide molecule amplification and labelling; submitting the solution to at least 2 thermal cycles having at least 2 and preferably 3 different temperature steps in order to obtain labelled target nucleotide molecule by PCR amplification; performing at least a measurement of the labelled target nucleotide molecule in at least one thermal cycle by incubating the labelled target nucleotide molecule under conditions allowing a specific binding between the target nucleotide molecule and its corresponding capture molecule and measuring the light emission from the bound labelled target nucleotide molecule in response to excitation light with the solution being present in the chamber and containing the labelled target nucleotide molecule. The surface of emission for a localized area is between about 0.1 μm2 and about 75 mm2. The method further includes processing the data obtained in at least one thermal cycle in order to detect and/or quantify the amount of nucleotide molecule present in the solution before the amplification.
US08247189B2 Modified flavin adenine dinucleotide-dependent glucose dehydrogenase
Provided is an enzyme that is further advantageous in terms of practical aspects when compared to publicly known enzymes for blood sugar sensors, and that can be used in a blood sugar level measuring reagent A flavin adenine dinucleotide-dependent glucose dehydrogenase that has amino acid sequence including a specific amino acid in an amino acid sequence shown in SEQ ID NO:2 or an amino acid sequence that has 60% homology therewith, and that has an improved temperature dependency.
US08247187B2 Method for detecting pathogens
The present invention relates generally to methods for detecting and identifying microorganisms and, more particularly, to methods for detecting microorganisms in a sample by incubating the sample at two temperatures to facilitate increased detection of the organism.
US08247181B2 Borrelia diagnostics and screening methods
Compositions and methods of detecting Borrelia proteins, nucleic acid sequences encoding these proteins, and subject antibodies to these proteins in a sample are disclosed.
US08247176B2 Method for separating an analyte from a sample
An analyte is separated from a fluid sample by introducing the sample into a cartridge having a sample port and a first flow path extending from the sample port. The first flow path includes an extraction chamber containing a solid support for capturing the analyte from the sample. The cartridge has a second flow path for eluting the captured analyte from the extraction chamber, the second flow diverging from the first flow path after passing through the extraction chamber. The sample is forced to flow through the extraction chamber and into a waste chamber, thereby capturing the analyte with the solid support as the sample flows through the extraction chamber. The captured analyte is then eluted from the extraction chamber by forcing an elution fluid to flow through the extraction chamber and along the second flow path.
US08247173B2 Spinocerebellar ataxia type 8 and methods of detection
The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.
US08247172B2 High muliplex nucleic acid amplification
This invention relates to the amplification of multiple nucleic acid target sequences. Forward and reverse compound primers comprising a common amplification sequence and a target-specific primer sequence are immobilized at a site on a solid support. Target regions of single-stranded template DNA are primed and copied by the forward primer to produce a first extension product. The template DNA is removed and the first extension product is primed and copied by the reverse primer to produce a second extension product. The second extension product has common amplification sequences at each end and is bulk-amplified in solution by regular PCR employing primers that target the common amplification sequences. These methods allow highly multiplexed amplifications to be performed.
US08247170B2 Detection of penicillin tolerance in Group B Streptococcus: single nucleotide polymorphisms in penicillin binding protein 4
Disclosed are methods of detecting penicillin tolerance in Group B Streptococcus by detecting at least one of two single nucleotide polymorphisms (SNP) in penicillin binding protein 4. Also disclosed are primers and hybridization probes that may be used in such methods.
US08247169B2 SiRNA targeting diacylglycerol O-acyltransferase homolog 2 (DGAT2)
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for DGAT2.
US08247168B2 Regulation of gene expression by protein methylation
The invention relates to the cDNA and deduced amino acid sequence of the Coactivator Associated arginine (R) Methyltransferase protein, CARM1. A method is described for the use CARM1 to regulate gene expression in vivo. CARM1 has also been used to methylate arginine residues of histones, synthetic peptides, and other proteins. A method to use CARM1 to screen for drugs that inhibit its methyltransferase activity is also described, as is a method to screen for drugs that modulate CARM1's interactions with other proteins.
US08247163B2 Preparing lithographic printing plates with enhanced contrast
Lithographic printing plates can be prepared with enhanced contrast between the image and background by coloring the imaged or exposed regions using a coloring fluid containing a water-insoluble colorant (dye or pigment) and an organic solvent that swells the imaged regions sufficiently for the colorant to be embedded or diffused therein.
US08247161B2 Resist composition for immersion exposure, method of forming resist pattern, and fluorine-containing resin
A resist composition for immersion exposure including: a base component (A) which exhibits changed solubility in an alkali developing solution under the action of acid; an acid-generator component (B) which generates acid upon exposure; and a fluorine-containing resin component (F); dissolved in an organic solvent (S), the fluorine-containing resin component (F) including a structural unit (f1) containing a fluorine atom, a structural unit (f2) containing a hydrophilic group-containing aliphatic hydrocarbon group, and a structural unit (f3) derived from an acrylate ester containing a tertiary alkyl group-containing group or an alkoxyalkyl group.
US08247160B2 Resist composition, method of forming resist pattern, and novel compound and acid generator
A resist composition including a base component that exhibits changed solubility in an alkali developing solution under the action of acid, and an acid generator consisting of a compound represented by general formula (b1). In formula (b1), Y1 represents a fluorinated alkylene group of 1 to 4 carbon atoms, X represents an aliphatic cyclic group of 3 to 30 carbon atoms, R11′ to R13′ each represents an aryl group or alkyl group, provided that at least one of R11′ to R13′ is an aryl group having a substituent represented by general formula (b1-0), and two alkyl groups among R11′ to R13′ may be bonded to each other to form a ring with the sulfur atom in the formula. In formula (b1-0), R52 represents a chain-like or cyclic hydrocarbon group, and f and g each represents 0 or 1.
US08247155B2 Production of toner for use in printing applications
The present invention provides a process for producing a colored toner comprising the steps of: providing a polymer composition comprising at least one polymer wherein the at least one polymer has a softening temperature from about 30° C. to about 160° C.; and a colorant; forming an aqueous mineral suspension of at least one multivalent metal phosphate by contacting a water-soluble salt of the multivalent metal with an aqueous solution comprising: a water-soluble phosphate salt; and at least one crystal growth inhibitor which controls the growth of the at least one multivalent metal phosphate, wherein the pH of the aqueous mineral suspension is from 5.5 to 14; and forming a dispersion of the polymer composition by adding the polymer composition to the aqueous mineral suspension under agitation to form a solid portion comprising dispersed particles of the polymer composition, wherein the temperature of the aqueous mineral suspension during the dispersing step is at least about 70° C.
US08247153B2 Process for producing resin microparticles for a toner raw material
An object of the present invention is to provide a resin microparticle for a toner raw material that has a small particle diameter and a narrow particle diameter distribution and has a low odor.There are provided a resin microparticle for a toner raw material characterized in that all of the following requirements (i) to (iii) are satisfied: Requirement (i): A particle diameter of 50% volume (D50) satisfies the relationship 0.05 μm≦D50≦1 μm; Requirement (ii): A particle diameter of 10% volume (D10) and a particle diameter of 90% volume (D90) satisfy the relationship D90/D10≦7; and Requirement (iii): The content of an organic solvent is not more than 70 ppm.
US08247146B2 Toners with reduced plasticization and blocking qualities
Use of a wax in a toner, such as carnauba wax, to give an increase in charge control agent in a toner, such as a magenta toner, to give an increased glass transition temperature is disclosed. The toner may contain a resin comprising amorphous and crystalline polyesters to provide good low melt characteristics.
US08247145B2 Magenta toner for developing electrostatic image
A magenta toner for developing an electrostatic image, the magenta toner comprising at least a binder resin and a magenta colorant, wherein the magenta colorant comprises a compound represented by Formula (1), wherein D is represented by one of Formulas (2) to (4):
US08247144B2 Photoreceptor for electrophotography
An object of the invention is to provide a photoreceptor for electrophotography which has a low residual potential in an initial stage, is inhibited from increasing in residual potential, is prevented from decreasing in charge potential, and undergoes little fatigue deterioration even upon repeated use. The invention relates to a photoreceptor for electrophotography which has a photosensitive layer containing a cyclic phenol sulfide represented by the following general formula (1): and one or more charge-transporting agents each having an arylamino group in the molecule, and which has excellent durability.
US08247141B2 Method of generating reticle data, memory medium storing program for generating reticle data and method of producing reticle
A method of generating reticle data for producing a reticle, a pattern of the reticle including a main pattern, a first auxiliary pattern, and a second auxiliary pattern, the first auxiliary pattern and the second auxiliary pattern being patterns not to resolve, light having passed through the first auxiliary pattern and light having passed through the main pattern being in phase, and light having passed through the second auxiliary pattern and light having passed through the main pattern having a phase difference of 180° from each other, the method comprising the step of deleting either of the first auxiliary pattern and the second auxiliary pattern or deforming at least either of the first auxiliary pattern and the second auxiliary pattern when the first auxiliary pattern and the second auxiliary pattern overlap each other.
US08247137B2 Fuel cell and production of fuel cell stack
Separators (5A, 5B, 6) and membrane-electrode assemblies (2) of a fuel cell stack (1) are alternately stacked in a guide box (40). The separators (5A, 5B, 6) each have groove-like gas paths (10A, 10B). Powder of an adhesive agent (7) is adhered in advance to the surfaces of the separators (5A, 5B, 6), except the gas paths (10A, 10B), through photosensitive drums (31A, 31B) to which the powder is adsorbed in a given pattern. The separators (5A, 5B, 6) and the membrane-electrode assemblies (2), stacked in the guide box (40), are heated and compressed by a press (43) and heaters (40C) to obtain a unitized fuel cell stack (1).
US08247132B2 Heat recovery apparatus and fuel cell having the same
Provided are a heat recovery apparatus recovering heat generated from a membrane electrode assembly (MEA) and transmitting the heat to a fuel spreader so that a temperature difference between the MEA and the fuel spreader inside a fuel cell is reduced, and a fuel cell having the heat recovery apparatus. The fuel spreader supplies fuel having a uniform concentration to the MEA through the heat recovery apparatus, so that a fuel cell having a reduced total volume, a stable performance, and increased energy efficiency can be provided.
US08247127B2 Fuel cell and method of operating fuel cell
A fuel cell stack is divided into a main power generation portion and a sub power generation portion. A variable load large in variation of output current is connected to the main power generation portion located upstream in a fuel flow and a steady load small in variation of output current is connected to the sub power generation portion located downstream in the fuel flow. This causes a fuel cell unit constituting the sub power generation portion to continue consuming a constant fuel by constant power generation and also causes hydrogen gas to continue flowing at a constant flow rate into the fuel cell unit, thereby preventing impurity gas concentrated and stored in the fuel cell unit from diffusing toward the upstream.
US08247126B2 Anode loop pressure control in PEM fuel cell system
A method of controlling pressure of a fuel gas in a fuel cell stack is disclosed. The method includes establishing a specification for a fuel gas/oxidant gas delta pressure vs. time value, operating the fuel cell stack, monitoring the fuel gas/oxidant gas delta pressure vs. time value and reducing stress resulting from excessive pressure of the fuel gas by implementing at least one of the following: (1) inducing the fuel cell stack to convert excess fuel gas into electrical current; (2) shutting off supply of the fuel gas to the fuel cell stack; and (3) and raising an operating pressure of the fuel cell stack when the fuel gas/oxidant gas delta pressure vs. time value strays beyond the specification.
US08247124B2 Carbon dioxide recirculating apparatus
Carbon dioxide recirculating apparatus (20, 120) is disclosed for use in an arrangement having combination means (115) and a path for the flow of a gas through the combustion means (115). The apparatus (20, 120) comprises extraction means (221) for extracting carbon dioxide from a first region of the path downstream of the combustion means (115). It further includes condensing means (26, 30) for condensing the extracted carbon dioxide, and feed means (36, 136) for feeding the condensed carbon dioxide to a second region of the path upstream of the combustion means.
US08247122B2 Device and method for controlling fuel cell system with vibration amplitude detection
A fuel cell system has a fuel cell generating power using a fuel gas and an oxidizing agent gas serving as materials of the system and a material supply section supplying the materials to the fuel cell. The power generated by the fuel cell is extracted to a load. A device for controlling the fuel cell system has: a material flow calculation section calculating a material flow supplied to the fuel cell so as to cause the fuel cell to generate the power of a required power generation amount; a material reduction limit detection section calculating a limit for reducing the material flow, based on a power generation state of the fuel cell; and a material flow change section controlling the material supply section so as to change the material flow calculated by the material flow calculation section to the limit calculated by the material reduction limit detection section.
US08247121B2 Fuel cell system with purging and method of operating the same
Upon stop of electric power generation of a fuel cell a hydrogen shutoff valve is closed, and a cathode is purged. At the same time, an air introducing valve and the purge valve are opened. The air taken in by the compressor is introduced into the anode through the air introducing tube to exhaust the hydrogen remaining in the anode to replace the hydrogen with the air. When the replacement of the hydrogen with the air has been finished, the compressor is turned off and the air introducing valve and the purge valve are opened. After that, if a temperature of the fuel cell is determined to be equal to or lower than a threshold “a”, a cathode-prioritized purge and an anode-prioritized purging are performed.
US08247112B2 Electrolyte, electrolyte solution for lithium-ion secondary battery comprising the electrolyte, and lithium-ion secondary battery using the electrolyte solution
An object of the present invention is to provide an electrolyte solution for lithium-ion secondary batteries comprising a tetraalkylphosphonium salt which improves the cycle characteristics and safety of lithium-ion batteries, and to provide a lithium-ion secondary battery using the electrolyte solution. Disclosed is an electrolyte comprising a tetraalkylphosphonium salt represented by general formula (1) wherein R1 represents a linear, branched or alicyclic alkyl group having 2 to 6 carbon atoms and R2 represents a linear, branched or alicyclic alkyl group having 1 to 14 carbon atoms, provided that R1 and R2 are different from each other and the total number of carbon atoms in the phosphonium cation is 20 or less; and X represents an anion.
US08247103B2 Battery cover mechanism
A battery cover mechanism for a portable electronic device includes a housing, a door, two first elastic members and a holding unit, the housing defines a cutout, the door slidably engage with the cutout, the cutout is closed by the door with the elastic resisting the door, the door can be opened by external force and not be removed from the housing, thus, a battery can be assembled in the housing.
US08247101B2 Active material for battery, non-aqueous electrolyte battery and battery pack
A non-aqueous electrolyte battery includes a container, a positive electrode housed in the container, a negative electrode housed in the container with a space from the positive electrode and containing an active material, and a non-aqueous electrolyte housed in the container. The active material includes a lithium-titanium composite oxide particle and a coating layer formed on at least a part of the surface of the particle, the coating layer being contained at least one element selected from the group consisting of phosphorous and sulfur or a phosphorous compound or a sulfur compound.
US08247100B2 Electrochemical device
An electrochemical device having an electrode matrix including a multilayer structure laminating positive and negative electrodes with a separator interposed therebetween; wherein at least one of the positive and negative electrodes has a resistance control layer at least at an edge part exposed when the separator thermally shrinks on a surface on the separator side; and wherein the resistance control layer has a resistance value as a total resistance value of the electrode matrix falling in such a range that an estimated internal short circuit current between the positive and negative electrodes is equivalent to 0.09 C to 1 C.
US08247096B2 Negative electrode for non-aqueous electrolyte secondary battery and non-aqueous electrolyte secondary battery
In a non-aqueous electrolyte secondary battery 1 including a positive electrode 11, a negative electrode 12, a separator 14, a positive electrode lead 15, a negative electrode lead 16, a gasket 17, and a housing case 18, the negative electrode 12 including a negative electrode active material layer 12b including an alloy-formable active material, a resin layer 13 is formed on the surface of the negative electrode active material layer 12b. The resin layer 13 includes a resin component with lithium ion conductivity and an additive for non-aqueous electrolyte. This configuration enables the battery performance to be maintained at a high level and the battery swelling to be suppressed, even when the number of charge/discharge cycles is increased, providing the non-aqueous electrolyte secondary battery 1 with a high level of safety.
US08247094B2 Perpendicular magnetic recording medium and magnetic recording and reproducing apparatus
The present invention relates to a perpendicular magnetic recording medium including a nonmagnetic substrate, and at least a soft magnetic layer (SUL), an alignment control layer, a magnetic recording layer and a protective layer formed on the nonmagnetic substrate; wherein the magnetic recording layer is constituted of three or more layers and includes a first magnetic recording layer, a second magnetic recording layer and a third magnetic recording layer from the substrate side, and also includes an exchange coupling reduction layer for reducing exchange coupling of both layers between the second magnetic recording layer and the third magnetic recording layer and, regarding magnetocrystalline anisotropic energy Ku of each magnetic recording layer, the first magnetic recording layer has 4×106 erg/cc or higher, the second magnetic recording layer has 2×106 erg/cc or lower and the third magnetic recording layer has 1×106 erg/cc or lower. The present invention also relates to a magnetic recording and reproducing apparatus using the perpendicular magnetic recording medium.
US08247090B2 Heterocyclic compound and organic electroluminescent device comprising the same
Provided are a heterocyclic compound represented by Formula 1 below and an organic electroluminescent device including an organic layer comprising the heterocyclic compound: wherein Ar1, Ar2, Ar3, R1, and R2 are the same as defined in the detailed description. The heterocyclic compound represented by Formula 1 has excellent electrical characteristics and an excellent charge transporting capability, and thus the heterocyclic compound of Formula 1 can be used as a hole injecting material, a hole transporting material, and/or a light emitting material that are suitable for all-color fluorescent and phosphorescent organic light emitting devices such as red, green, blue, and white fluorescent and phosphorescent organic light emitting devices. In addition, the organic electroluminescent device including an organic layer comprising the heterocyclic compound represented by Formula 1 can have a high efficiency, a low driving voltage, and high luminosity.
US08247081B2 Composite articles made by process for joining stainless steel part and titanium carbide ceramic part
A process for joining a stainless steel part and a titanium carbide ceramic part comprising: providing a SUS part, a TiC ceramic part, a Ti foil and a Fe foil; placing the TiC ceramic part, the Ti foil, the Fe foil, and the SUS part into a mold, the Ti foil and the Fe foil located between the TiC ceramic part and the SUS part, the Ti foil abutting the TiC ceramic part, the Fe foil abutting the SUS part and the Ti foil; placing the mold into a chamber of an hot press sintering device, heating the chamber and pressing the SUS part, the TiC ceramic part, the Ti foil, and the Fe foil at least until the SUS part, the TiC ceramic part, the Ti foil and the Fe foil form a integral composite article.
US08247079B2 Laminate containing a silylated polyurethane adhesive composition
A laminate includes a backing material coated with an adhesive composition. The adhesive composition includes a cured silylated polyurethane composition derived from polyester based polyurethane prepolymer. The silylated polyurethane composition when partially silylated is especially useful for pressure sensitive adhesives where it imparts superior adhesive and cohesive performance thereto.
US08247076B2 Flame retardant additive of fluoropolymers in flame retardants
Composition comprising fluoropolymers, such as polytetrafluoroethylene (PTFE), poly(hexafluoroethylene), poly(tetrafluoroethylene-hexafluoroethylene), and poly(tetrafluoroethylene-ethylene-propylene), which are dispersed in flame retardants, such as organic, bromine compounds and/or organic phosphorus compounds, and that consist of particles that comprise one or more fluoropolymers and flame retardants. The fluoropolymers may be enveloped by the flame retardant.
US08247072B2 Resol beads, methods of making them and methods of using them
Resol beads are disclosed that are prepared in high yield by reaction of a phenol with an aldehyde, with a base as catalyst, a colloidal stabilizer, and optionally a surfactant. The resol beads have a variety of uses, and may be thermally treated and carbonized to obtain activated carbon beads.
US08247071B2 Insulating coating composition and an insulated wire, and a coil formed using the same
An insulating coating composition that improves lubricity without reduction of the varnish adhesion strength and an insulated wire using the insulating coating composition, and a coil using the insulated wire are provided. An insulating coating composition comprises a polyamide-imide resin, which is obtained through a synthetic reaction of isocyanate component with acid component, and a lubricant component, wherein the terminal isocyanate group of the polyamide-imide resin is capped with a blocking agent of higher alcohol having a carbon number of eight or more.
US08247066B2 Teflon fuser member containing fluorinated nano diamonds
Exemplary embodiments provide a coating composition for an outermost layer of a fuser member that can include a plurality of fluorinated diamond-containing particles dispersed in a fluororesin matrix.
US08247065B2 Linear polymers, polymer blends, and articles made therefrom
Provided are blends of linear low density polyethylene copolymers with very low density, low density, medium density, high density, and differentiated polyethylenes and other polymers. The invention also includes articles produced from the linear low density polyethylene and polyethylene blends described herein.
US08247061B2 Method for calibrating the measurements of an annular body
Disclosed is a method for calibrating an annular-shaped body which is made of thermoplastic or at least partially crystalline plastic material, to an annular-shaped body which is produced according to the method, and to an oscillating object which is used in the method. Also disclosed is an oscillating object which is used to stimulate oscillations and which is introduced into an annular-shaped body by means of axial forward motion. Localized warming of the annular-shaped body is performed until the glass transition temperature of the material thereof is exceeded by localized contact of the oscillating object with the annular-shaped body. A desired, economical internal measurement having high precision is produced when the calibration section of the oscillating body is immersed into the annular-shaped body.
US08247058B2 Information recording medium and manufacturing method thereof
An information recording medium (9) comprises an information layer (9a) in which concavo-convex marks are formed, and a recording layer (13), contained within the information layer (9a), in which added marks are formed by optical properties changing through laser irradiation, and that contains Te, O, and M (where M is at least one element selected from a group consisting of Pd, Au, Pt, Ag, Cu, and Ni). In this information recording medium (9), a pre-laser irradiation reflectance Ra and a post laser irradiation reflectance Rb fulfill 1.0
US08247056B2 Label assembly and method of using the same to label articles durably yet removably
A label assembly and method of using the same to label articles durably, yet removably. In one embodiment, the label assembly is used to label fabric articles, such as clothing, and comprises (a) an image forming laminate for forming an image on the fabric article, the image forming laminate comprising an ink layer, the ink layer being bondable to the fabric article; and (b) an image removing laminate for removing the image from the fabric article, the image removing laminate comprising a remover layer, the remover layer, upon being activated by heat and/or light, being bondable to the ink layer of the image forming laminate; (c) whereby, upon bonding of the image removing laminate to the ink layer, the bonding between the image removing laminate and the ink layer is stronger than the bonding between the ink layer and the fabric article.
US08247047B2 Deep drawing packaging container, deep drawing packaged product and method of manufacturing the same
A deep drawn container with a top film made of a first heat shrinkable multilayer film, and a bottom film made of a second heat shrinkable multilayer film. The deep drawn container having a drawing ratio (D1) of the top film and a drawing ratio (D2) of the bottom film satisfying conditions: D1=1.1 to 4.0; D2=1.5 to 5.0; and (D2/D1)=1.05 to 4.55. A hot-water shrinkability of the first heat shrinkable multilayer film in a longitudinal direction (SM1) and in a transverse direction (ST1), and a hot-water shrinkability of the second heat shrinkable multilayer film in a longitudinal direction (SM2) and in a transverse direction (ST2) satisfy conditions: SM1=5 to 40%; ST1=5 to 40%; SM2=2 to 25%; ST2=2 to 25%; (SM1/SM2)=1.2 to 12; and (ST1/ST2)=1.2 to 12.
US08247043B2 Recording medium
The invention provides a recording medium capable of inhibiting occurrence of undertrapping, lowering the visibility of scratches on the outermost surface of the recording medium and inhibiting occurrence of a mottled pattern when recording is conducted. The recording medium has a substrate and an ink receiving layer provided on the substrate, wherein the arithmetic average roughness Ra of the outermost surface of the recording medium as prescribed by JIS B 0601:2001 is 1.1 μm or more and 2.5 μm or less, and the skewness Rsk of a roughness curve of the outermost surface of the recording medium as prescribed by JIS B 0601:2001 is 0.1 or less.
US08247041B2 Cellulose acylate film
A cellulose acylate film produced by a melt-casting film formation, wherein the total of the number of projections having a height of from 0.1 μm to 100 μm and a length of at least 1 mm and the number of depressions having a depth of from 0.1 μm to 100 μm and a length of at least 1 mm is at most 10 per 10 cm of the width of the film. When built in a liquid-crystal display device, the cellulose acylate film significantly reduces the display blur in the device.
US08247032B2 Methods utilizing scanning probe microscope tips and products therefor or produced thereby
The invention provides a lithographic method referred to as “dip pen” nanolithography (DPN). The method include the following steps: (i) providing a substrate and a scanning probe microscope tip; (ii) coating the tip with a patterning compound and a solvent to form a wet tip; and (iii) contacting the coated tip with the substrate so that the compound is applied to the substrate so as to produce a desired pattern. The invention also provides substrates patterned by DPN and kits for performing DPN.
US08247030B2 Void-free copper filling of recessed features using a smooth non-agglomerated copper seed layer
A method is provided for controlling copper agglomeration on a substrate and for forming void-free bulk copper metal filling of recessed features in integrated circuits. In one embodiment, the method includes providing a substrate having a topography including a top surface and at least one recessed feature comprising at least a sidewall surface and a bottom surface, depositing a barrier film on the substrate topography, and depositing a metal-containing wetting film on the barrier film. The method further includes physical vapor depositing copper metal on the metal-containing wetting film, where the substrate temperature is sufficiently high to form a smooth copper metal seed layer on the metal-containing wetting film. Void-free bulk copper metal may be plated in the at least one recessed feature.
US08247026B2 Optical film and method for producing same
Disclosed is a method for producing an optical film composed of a transparent resin and a metal oxide, which film has high light transmittance and light diffusion property even it is formed thin. Also disclosed is such an optical film. Specifically disclosed is a method for producing an optical film having a total light transmittance of not less than 70% and a haze value of not less than 20%, which comprises a step (A) wherein a metal compound to form a metal oxide through a sol-gel reaction is subjected to a sol-gel reaction in a solvent; a step (B) for providing a solution containing a transparent resin as a solute; a step (C) for mixing the mixture obtained in the step (A) with the solution obtained in the step (B); and a step (D) wherein the mixture obtained in the step (C) is applied or spread over a substrate or container and then heated for evaporating the solvent, thereby forming a film thereon.
US08247025B2 Magnetic nanoparticle fabrication
Techniques for fabricating magnetic nanoparticles are provided. In one embodiment, a method performed under the control of at least one apparatus for fabricating magnetic nanoparticles includes preparing a substrate that defines at least one cavity through a portion thereof, soaking the substrate with a solution, the solution including a multiple number of magnetic nanoparticles, and applying a magnetic field so as to collect at least a portion of the magnetic nanoparticles into the at least one cavity.
US08247023B2 Method for making thermionic electron source
A method for making a thermionic electron source includes the following steps: (a) supplying a substrate; (b) forming a first electrode and a second electrode thereon; and (c) spanning a carbon nanotube film structure on a surface of the first electrode and the second electrode with a space defined between the thermionic emitter and the substrate.
US08247021B2 Liquid material arrangement method, color filter manufacturing method, and organic EL display device manufacturing method
A liquid material arrangement method includes performing a first pattern generating step, a dot deleting step, and a liquid material arranging step. The first pattern generating step includes generating a first dot pattern in which a first prescribed number of dots is set according to the prescribed region. The dot deleting step includes deleting a second prescribed number of dots from the first prescribed number of dots to generate a second dot pattern. The liquid material arranging step includes arranging a liquid material in a prescribed region on a substrate by causing a nozzle and the substrate to scan in relative manner and discharging the liquid material from the nozzle based on the second dot pattern. The performing of the dot deleting step further includes deleting at least one prohibited dot with priority with the prohibited dot being determined based on discharge information of the nozzle determined in advance.
US08247020B2 Methods of making medical devices
Scaffold-supported metal or pseudometallic film covers suitable for use as medical devices are disclosed together with methods of fabricating the devices. Methods for making the medical devices consist of either providing or forming a scaffold, then depositing a metallic or pseudometallic film cover onto the scaffold in such a manner as to form an integral, substantially monolithic junction between the deposited cover material and the scaffold.
US08247019B2 Coating sleeve
The present invention provides an apparatus and a method for modifying a structure such as a medical device through the selective application of a coating. A coating sleeve may comprise an elastomeric wall that may be permeable or impermeable to a coating material and may be porous so as to allow for patterned coating of the device. The coating sleeve may contain surface protrusions that facilitate manipulation by providing sites for grasping and pulling. In operation the coating sleeve may be fitted on the device prior to application of a coating and removed subsequent to application of the coating.
US08247016B2 Vegetable drink composition
A vegetable drink composition containing (A) from 0.1 to 15% by weight of one or more substances selected from the group consisting of water-soluble acidic polysaccharide dietary fiber, water-soluble neutral polysaccharide dietary fiber, and indigestible oligosaccharide; (B) 65% by weight or more of water; and (C) one or more vegetable juices; which is subjected to a heat sterilization treatment; has a vegetable solid content of from 0.001 to 0.09% by weight, wherein said vegetable solid is a solid material having a particle size of 833 μm or smaller; and has a pH of from 3 to 5.
US08247015B2 Yogurt-cheese products
Techniques for making a yogurt-cheese-oil product, comprising steps of: providing a milkfat-oil fluid comprising butterfat and an oil; pasteurizing the milkfat-oil fluid to produce a cheese-oil precursor; combining yogurt with the cheese-oil precursor to produce a combined yogurt-cheese-oil precursor; and homogenizing and acidifying the combined yogurt-cheese-oil precursor; producing a yogurt-cheese-oil product. Yogurt-cheese-oil products: comprising between about 10% by weight and about 80% by weight of total butterfat; comprising between about 2% by weight and about 52.5% by weight of an oil; comprising between about 10% by weight and about 50% by weight of yogurt; and yielding less than about 1% syneresis by weight after 15 hours at about 74° F. to about 75° F.
US08247013B2 Method for producing frozen dough
The present invention provides a method for producing frozen dough which can be directly transferred from freezer to oven without a proofing or thawing step. The process comprises mixing the dough ingredients, forming gas nucleation sites, exercising the dough by subjecting to cycles of pressure differentials and freezing the dough. The frozen product can be transferred directly from the freezer to an oven for baking.
US08247010B2 Accelerated low pressure brewer and a method for making a beverage
A brewing system (100) includes a brew group (130) having a cylindrical brewing chamber (132), a first actuator (146) attached to an upper piston assembly (140) that is movable to sealingly engage one end of the brewing chamber, a second actuator (156) attached to a lower piston assembly (150) that slidably engages the opposite end of the brewing chamber. The lower piston assembly includes a water supply tube (151) that engages a channel through the piston to supply heated water to the brewing chamber. The upper piston assembly includes a dispensing tube (141) that engages a channel through the piston to accommodate dispensing the brewed liquid. A sliding arm assembly is positioned to remove spent grounds from the brewing assembly. The current embodiment includes a controller (100), hopper (112), water heater (11) and grinder assembly (120). An optional flavoring dispenser may also be provided.
US08247007B2 Composition for treating atopic dermatitis comprising extracts of bamboo and Scutellaria
The present invention relates to a composition comprising of plant extract as an active component, specifically, Bamboo extract and Scutellaria extract, for the treatment and prevention of atopic dermatitis. The present invention is a natural ingredient obtained from a plant. The present invention can control immune responses by inhibiting the release of histamine and leukotrien, and thus, has effect in the treatment or prevention of allergic diseases, inflammatory diseases and skin diseases, specifically atopic dermatitis. The present invention has been proven safe and beneficial effecting the treatment of atopic dermatitis through clinical trials, and thus, can be used for the treatment and prevention of atopic dermatitis.
US08247006B2 Composition and method of treating lipid encapsulated virus infections
A method of treating a patient infected with a lipid encapsulated virus by administering to the patient about 1000 mg to about 5000 mg per day of a nutritional supplement having from about 40 to about 80 wt. % L-lysine, from about 20 to about 50 wt. % butylated hydroxytoluene and from about 1 to about 10 wt. % Echinacea. Administration of the nutritional supplement inhibits ulcer formation resulting from lipid encapsulated virus infections such as herpes simplex I and II infections.
US08247002B2 Antioxidant material, anti-deterioration agent and food or beverage
An antioxidant material of the present invention contains flavonoid aglycon and vitamin C. The flavonoid aglycon is eriodictyol and/or diosmetin obtained by treatment of a raw material containing flavonoid glycoside derived from lemons, limes, or sudachis to form the aglycones thereof. It is preferred that this antioxidant material be produced through a step of mixing the flavonoid aglycon and the vitamin C after the treatment to form the aglycones. The treatment to form the aglycones is glycosidase treatment using a β-glycosidase derived from a microorganism of the genus Aspergillus or Penicillium multicolor, or microbial fermentative treatment using a microorganism of the genus Aspergillus. An anti-deterioration agent and a food or beverage of the present invention contain the antioxidant material.
US08246997B2 Compositions comprising solid particles encapsulated in a cross-linked silicone matrix, and methods of making the same
The present invention relates to topical compositions containing solid particles that are stabilized via encapsulation into a cross-linked silicone matrix. The solid particles are preferably formed of a metal oxide, such as zinc oxide or titanium dioxide, and the cross-linked silicone matrix is preferably formed by cross-linking a silicone having branched reactive alkoxyl moieties in the presence of a stannous carboxylate cross-linking agent. The stabilized particles of the present invention can readily be used either alone or in combination with other skin care actives to form topical compositions with improved stability and performance.
US08246994B2 Method for delivering an active agent using a hydrogel composition
New hydrogel, including a hydrogel containing cationic BSA is included in a vaccine to stimulate the immune system to increase the potency of the vaccine.
US08246989B2 Dosage forms of bisphosphonates
Oral dosage forms of a bisphosphonate comprised of a safe and effective amount of a pharmaceutical composition comprising a bisphosphonate, a chelating agent, and, means for effecting delayed release of the bisphosphonate and the chelating agent in the lower gastrointestinal tract provide delivery of the pharmaceutical composition to the lower gastrointestinal tract of the mammal subject and pharmaceutically effective absorption of the bisphosphonate with or without food or beverages. The present invention substantially alleviates the interaction between bisphosphonates and food or beverages, which interaction results in the bisphosphonate active ingredient not being available for absorption. The resulting oral dosage form may thus be taken with or without food. Further, the present invention effects delivery of the bisphosphonate and the chelating agent to the lower GI tract, substantially alleviating the upper GI irritation associated with bisphosphonate therapies. These benefits simplify previously complex treatment regimens and can lead to increased patient compliance with bisphosphonate therapies.
US08246988B2 Three layer tablet containing cetirizine, pseudoephedrine, and naproxen
In one aspect, the present invention features a tablet including a first drug layer, a second drug layer, and a third drug layer, wherein (i) the first drug layer includes naproxen; (ii) a second drug layer including pseudoephedrine; and (iii) the third drug layer includes cetirizine; wherein the first drug layer is in contact with the second drug layer, the third drug layer is in contact with the second drug layer, and the first drug layer is not in contact with the third drug layer, and wherein the second drug layer is a sustained release layer adapted to deliver a therapeutically effective amount of pseudoephedrine for a period of at least twelve hours.
US08246987B2 Controlled release composition and method of producing the same
A controlled release composition containing a physiologically active substance in high content, suppressing the initial excess release, and achieving a stable release speed over a long period of time is provided.A controlled release composition comprising (1) a physiologically active substance or salt thereof in an amount of about 14% (w/w) to about 24% (w/w) based on the total composition weight, (2) hydroxynaphthoic acid selected from the group consisting of 3-hydroxy-2-naphthoic acid and 1-hydroxy-2-naphthoic acid or salt thereof, and (3) a lactic acid polymer or salt thereof having a weight-average molecular weight of 15000 to 50000 in which the content of polymers having molecular weights of 5000 or less is about 5% by weight or less, wherein the molar ratio of said hydroxynaphthoic acid or salt thereof to said physiologically active substance or salt thereof is from 3:4 to 4:3.
US08246985B2 Pharmaceutical composition comprising lipase inhibitor and lipophilic oil absorbent and oral formulation prepared therefrom
This invention provides a pharmaceutical composition comprising a lipase inhibitor; a lipophilic oil absorbent selected from the group consisting of hydrogenated castor oil, hydrogenated vegetable oil, glyceryl behenate, glyceryl palmitostearate and a mixture thereof; and a pharmaceutically acceptable additive, an oral formulation of a lipase inhibitor prepared there from and a method for preparing said formulation. The formulation of the present invention can minimize side effects such as oily spotting, fatty/oily stool, abdominal distension and flatus, and thus it can be advantageously used for preventing or treating obesity and hyperlipaemia.
US08246984B2 Formulation of insoluble small molecule therapeutics in lipid-based carriers
The present invention provides formulations containing at least one unsaturated amphiphilic lipid and an amphipathic or hydrophobic drug and methods of making these formulations. In particular, the present invention provides formulations of at least one unsaturated phospholipid and an amphipathic or hydrophobic pyrimidine drug, methods of making these formulations and the use of such formulations in a variety of contexts, including, for example, the treatment of proliferative disorders, such as tumors and cancers.
US08246982B2 Pressure-sensitive adhesives based on ethylene-vinyl acetate copolymers and adhesive resins, for medical application purposes
A pressure sensitive adhesive for medicinal application purposes, based on ethylene-vinyl acetate copolymers is characterized in that it contains as polymer component (A) an ethylene-vinyl acetate copolymer or a combination of at least two ethylene-vinyl acetate copolymers, and as component (B) an adhesive resin or a combination of adhesive resins at a portion of up to 55%-wt, relative to the sum of components (A) and (B) without active substances or other auxiliary substances.
US08246979B2 Transdermal delivery system for the administration of rotigotine
An improved transdermal delivery system (TDS) comprises a self-adhesive matrix comprising a solid or semi-solid semi-permeable polymer which contains rotigotine in its free base form as a multitude of microreservoirs within the matrix. The self-adhesive matrix is highly permeable to the free base of rotigotine and is impermeable to the protonated form of rotigotine.
US08246976B2 Transdermal delivery of drugs based on crystal size
A blend of at least two polymers in combination with a drug provides a pressure-sensitive adhesive composition for a transdermal drug delivery system in which the drug is delivered from the pressure-sensitive adhesive composition and through dermis when the pressure-sensitive adhesive composition is in contact with human skin. According to the invention, providing drug having differing crystal sizes as well as drug which is solublized in the pressure-sensitive adhesive composition controls the rate of drug delivery from the pressure-sensitive adhesive composition.
US08246975B2 Drug, drug guidance system, magnetic detection system, and drug design method
It is intended to provide a drug delivery system which makes it possible to solve the existing technical problems and is easily usable in practice. A drug, which comprises an organic compound or an inorganic compound and has been magnetized by modifying a side chain and/or crosslinking side chains, is induced by a magnetic force into target tissues or an affected part.
US08246967B2 Compounds with modifying activity enhanced under hypoxic conditions
Compositions and methods for modifying one or more biologic targets are provided. Suitable targets include cells, DNA, proteins, enzymes, and/or a subject in need thereof. The compositions may exist as a monomer or multimer and are active in a biologic environment with enhanced activity in hypoxic environments and, thus, exhibit improved specificity for hypoxic biologic targets (e.g., tumorigenic cells and those undergoing uncontrolled cell growth). A composition typically comprises a complex with an overall charge of 2+ or greater having at least one ruthenium atom attached to a redox active ligand. The redox active ligand helps maintain separation of more than one ruthenium atom. Suitable compositions may further include a terminal ligand comprising a heterocyclic aromatic compound. When provided to a biologic target, the composition modifies the biologic target and no additional compounds need be provided. Suitable compositions are typically catalytic and regenerative in the presence of a reducing agent.
US08246960B2 Methods and compositions for generating bioactive assemblies of increased complexity and uses
The present invention concerns methods and compositions for making and using bioactive assemblies of defined compositions, which may have multiple functionalities and/or binding specificities. In particular embodiments, the bioactive assembly is formed using dock-and-lock (DNL) methodology, which takes advantage of the specific binding interaction between dimerization and docking domains (DDD) and anchoring domains (AD) to form the assembly. In various embodiments, one or more effectors may be attached to a DDD or AD sequence. Complementary AD or DDD sequences may be attached to an adaptor module that forms the core of the bioactive assembly, allowing formation of the assembly through the specific DDD/AD binding interactions. Such assemblies may be attached to a wide variety of effector moieties for treatment, detection and/or diagnosis of a disease, pathogen infection or other medical or veterinary condition.
US08246958B2 Methods of inhibiting alpha-4-dependent interactions with VCAM-1 with anti-VLA-4 antibodies
The invention provides methods of treatment using humanized immunoglobulins that specifically bind to alpha-4 integrin. The methods are useful for treatment of asthma, atherosclerosis, AIDS dementia, diabetes, inflammatory bowel disease, rheumatoid arthritis, transplant rejection, graft versus host disease, tumor metastasis, nephritis, atopic dermatitis, psoriasis, myocardial ischemia, and acute leukocyte mediated lung injury.
US08246954B2 Methods of treating amyloidosis with humanized anti-beta-amyloid antibodies
The present invention is related to chimeric and humanized antibody and to methods and compositions for the therapeutic and diagnostic use in the treatment of amyloidosis, a group of disorders and abnormalities associated with amyloid protein such as Alzheimer's disease.
US08246952B2 Method of increasing radiation sensitivity by inhibition of beta one integrin
A method for increasing or monitoring apoptosis in tumor cells by the co-administration of ionizing radiation and an anti-integrin antibody. Increasing apoptosis reduces tumor growth in vivo and in a cell culture model. The antibody is directed against the beta-1 integrin subunit and is inhibitory of beta-1 integrin signaling. Other molecules having an inhibitory effect on beta-1 integrin, either in signaling or in binding to its cognate extracellular receptors may also be used. The present method is particularly of interest in treatment of tumor cells associated with breast cancer, wherein radiation is currently used alone. The present method further contemplates a monoclonal antibody suitable for human administration that may further comprise a radioisotope attached thereto.
US08246949B2 Methods and devices for sustained in-vivo release of an active agent
The present invention includes methods and devices for providing sustained in-vivo release of an active agent to a subject. In some aspects, such release may be achieved by reacting an active agent in-vivo with a depot forming agent in order to form a sustained release active agent depot inside the subject. The depot can then release the active agent over a sustained period of time.
US08246948B2 Stimulation of cartilage formation using reduced pressure treatment
A method of inducing new cartilage growth from periosteum in a mammal is provided. The method includes positioning a foam manifold in contact with the periosteum and positioning a drape over the foam manifold and the periosteum to create a sealed space between the drape and the periosteum. A reduced pressure is applied to the sealed space.
US08246946B2 Treatment of bipolar disorder utilizing anti-fungal compositions
A method for treatment or prophylaxis of a bipolar disorder disease state, by administration of an anti-fungal composition that includes at least one of the bacilli (1) Bacillus subtilis, (2) Bacillus coagulans, and (3) Enterococcus faecium.
US08246945B2 Methods and reagents for decreasing clinical reaction to allergy
The present invention provides methods and compositions for treating or preventing allergic reactions, particularly anaphylactic reactions. Methods of the present invention involve administering microorganisms to allergic subjects, where the microorganisms contain a recombinant version of the protein allergen. The recombinant version can be wild-type or may include mutations within IgE epitopes of the protein allergen. Preferably the compositions are administered rectally. Particularly preferred microorganisms are bacteria such as E. coli. Any allergen may be used in the inventive methods. Particularly preferred allergens are anaphylactic allergens including protein allergens found in foods, venoms, drugs and latex. The inventive compositions and methods are demonstrated in the treatment of peanut-induced anaphylaxis.
US08246944B2 Immunotherapeutic agent for the combined treatment of tuberculosis in association with other drugs
This invention refers to an immunotherapeutic agent based on cell wall fragments from virulent Mycobacterium tuberculosis strains, to a method for obtaining this immunotherapeutic agent, to pharmaceutical formulations containing it and to its use for the preparation of a drug for the combined treatment of tuberculosis in association with other drugs.
US08246942B2 Microbicidal compositions
The invention relates to synergistic mixtures of o-phenylphenol with other microbicidally active compounds, such as bronopol (2-bromo-2-nitro-1,3-propanedial), 2-methyl-2H-isothiazol-3-one, 1,2-dibromo-2,4-dicyanobutane.
US08246940B2 Cosmetic composition comprising gellan gum or a derivative thereof, a fixing polymer, a monovalent salt and an alcohol, process of using the same
The present disclosure relates to a cosmetic composition comprising, in a cosmetically acceptable medium, at least one gum chosen from gellan gums and derivatives thereof, at least one fixing polymer, at least one monovalent salt, and at least one alcohol. Further disclosed herein is a process for shaping and/or holding the hairstyle using the same.
US08246935B2 Dry powder formulations
A dry powder suitable for inhalation n a dry powder inhaler, the powder comprising a carrier, an active agent and at least 0.5% by weight of magnesium stearate, the powder being further characterized in that the less than 10% of the surface of the carrier material is covered with particles of magnesium stearate. The invention is also directed to a method of making dry powders by blending together the ingredients mentioned in a diffusion blender for a period of time that is less than 60 minutes.
US08246934B2 Respiratory dispersion for metered dose inhalers comprising perforated microstructures
A respiratory dispersion for pulmonary delivery comprises one or more bioactive agents, a suspension medium, and a plurality of perforated microstructures having a mean aerodynamic diameter of less than 5 μm. The suspension medium comprises at least one propellant and permeates the perforated microstructures.
US08246933B2 Aerosol method for nano silver-silica composite anti-microbial agent
A method of forming and resulting nano-structured composite includes atomizing a mixture of an amount of each of aminopropyltriethoxysilane, AgNO3, DI water, and ethanol in a carrier gas; heating the atomized droplets at a selected temperature for a time sufficient to reduce the Ag to its elemental form in a silica matrix; and outputting the nano structured composite particles. A predetermined heating time is from about 0.01 to about 40 seconds and a selected heating temperature is from about 200 to about 800° C. The nano structured composite includes a plurality of nano particles at a contact surface of the composite, dispersed throughout and at a contact surface of the composite, or dispersed throughout the composite.
US08246929B2 Synthesis of sodium potassium niobate by sol-gel
A method for producing a biocompatible material of the formula NaxKyNbO3, 0≦x≦0.8, 0.2≦y≦1, x+y=1 includes the steps of a) providing a Na-precursor and a K-precursor for NaxKyNbO3, b) mixing the precursors in solution wherein said precursors first react to form a sol and thereafter a gel, c) heat treating the gel to obtain an oxide of the material NaxKyNbO3, 0≦x≦0.8, 0.2≦y≦1, x+y=1. The material can be produced as a film, and the material or film can be provided on the exterior surface of a medical implant that will come into contact with body tissue and/or body fluids upon implantation thereof.
US08246926B2 Fullerene hollow structure needle crystal and C60-C70 mixed fine wire, and method for preparation thereof
A needle crystal in the form of a capsule comprising fullerene molecules such as C60 and a C60 platinum derivative and having a hollow portion (a fullerene shell capsule) is provided. The fullerene shell capsule which has been prepared by the liquid-liquid interface precipitation method, which comprises (1) a step in which a solution containing a first solvent dissolving fullerene therein is combined with a second solvent in which the solubility of fullerene is lower than in the above first solvent; (2) a step in which a liquid-liquid interface is formed between the above solution and the above second solvent; and (3) a step in which a carbon fine wire is precipitated on the above liquid-liquid interface, has a novel characteristic in its form and can be used as a catalyst supporting material, a raw material for a plastic composite material, a storage material for gas such as hydrogen, a catalyst for fuel cell, or the like. Further, provided are novel C60-C70 mixed fine wire which is fullerene fine wire comprising two components of C60 and C70, and a method for preparing the mixed fine wire.
US08246923B2 High Pd content diesel oxidation catalysts with improved hydrothermal durability
There is described Pd enriched diesel oxidation catalysts and their application as catalysts for the oxidation of CO and HC emissions from a compression ignition/diesel engine. The catalysts are characterized by increased performance and hydrothermal durability these goals being achieved by employing a layered design to eliminate low temperature catalyst quenching by toxic HC species in the exhaust stream.
US08246915B2 Heat-exchanger for carrying out an exothermic reaction
Disclosed is a removable cooling module (1), for use in a reactor (20) for carrying out an exothermic reaction, comprising a coolant feed tube (2); a distribution chamber (4); a plurality of circulation tubes (5); and a collection chamber (6); said coolant feed tube (2) having at its first end an inlet (3), for charging the coolant module (1) with coolant, and communicating with said distribution chamber (4) at its second end; each of said circulation tubes (5) communicating with the distribution chamber (4) through a first end and communicating with said collection chamber (6) through a second end; the collection chamber (6) having an outlet for discharging coolant. The modular nature of the invention facilitates removal of individual cooling module (1) from a reactor shell (21).
US08246910B2 Dielectric sensing method and system
Sensing device and method for detecting presence and concentration of generic target analytes of interest. The device and method are based on detecting changes in effective dielectric induced by the target analytes of interest. Applications of the invention include, but are not restricted to, detecting and characterizing the presence of chemical and/or biological target analytes of interest as well as detecting and characterizing target analytes of interest from a separation apparatus. In one embodiment of the invention, the device comprises at least two electrodes in a rigid architecture such as a solid surface, where the electrodes have sizes and inter-electrode spacings that are on the order of sizes of target analytes of interest to improve sensitivity of the device. Changes in effective dielectric and, therefore, capacitance induced by a presence of the target analytes of interest are measured electronically. The changes are used to detect the presence of the target analytes of interest and to characterize their presence.
US08246907B2 Automatic analyzer
An automatic analyzer and an automatic analyzing system to identify samples and reagents used in the analyzer and members used in measurement of at least two objects in common: system reagents or buffer solution; sensor parts; probes; nozzles; chips; dispensing cups; tubes; ISE electrodes; detectors; deionized water; and waste, and to unify management of identification information thereof and a measurement result.
US08246900B2 Annealing apparatus
Provided is an annealing apparatus, which is free from a problem of reduced light energy efficiency resulted by the reduction of light emission amount due to a heat generation and capable of maintaining stable performance. The apparatus includes: a processing chamber 1 for accommodating a wafer W; heating sources 17a and 17b including LEDs 33 and facing the surface of the wafer W to irradiate light on the wafer W; light-transmitting members 18a and 18b arranged in alignment with the heating sources 17a and 17b to transmit the light emitted from the LEDs 33; cooling members 4a and 4b supporting the light-transmitting members 18a and 18b at opposite side to the processing chamber 1 to make direct contact with the heating sources 17a and 17b and made of a material of high thermal conductivity; and a cooling mechanism for cooling the cooling members 4a and 4b with a coolant.
US08246898B2 Method and apparatus for enhanced fiber bundle dispersion with a divergent fiber draw unit
A method and associated apparatus for melt extruding a nonwoven web includes providing a plurality of fibers from an extrusion device. The fibers are conveyed through a diverging profile portion of a fiber drawing unit (FDU) that causes the fibers to spread and expand in the machine direction within the FDU. The fibers are then conveyed through a diverging diffusion chamber spaced from the outlet of the FDU to reduce the velocity of the fibers and further spread the fibers in the machine direction. The fibers may be subjected to an applied electrostatic charge in either the diffusion chamber or the FDU. From the outlet of the diffusion chamber, the fibers are laid onto a forming surface as a nonwoven web.
US08246897B2 Method and appartus for the vulcanisation of tyres for vehicle wheels
A vulcanization apparatus and method for vehicle wheel tires, includes at least one prevulcanization work station to conduct a prevulcanization of a radially internal portion of the tire and at least two vulcanization work stations wherein the remaining part of the vulcanization of the whole tire is carried out.
US08246892B2 Methods of quality control in concrete block production
The invention relates to a method of controlling the quality of blocks that are produced front face-up in a mold, and verifying the accuracy of the production of such blocks, to ensure that the blocks are manufactured with consistent quality and minimal block-to-block variability. Measurement locations are formed on the front faces of predetermined blocks. By measuring the distances between the measurement locations and the rear faces and comparing with a target distance, any variation provides an indication that the blocks are not being properly formed. The process variables, such as the alignment of the compression head and/or the pressure plates to the mold, can then be adjusted accordingly.
US08246885B2 Method and assembly for the manufacture of an absorbent sheet, and absorbent sheet obtained
The invention relates to a process for manufacturing an absorbent sheet comprising at least two plies of cellulose wadding, consisting in combining said plies under pressure by passing between two steel cylindrical components, the first being smooth on the outside and the second being equipped with raised components on the outside and the hardness of the first cylindrical component being lower than that of the second cylindrical component. According to the invention, the first cylindrical component has a treated hardened surface layer and a deformable underlayer; the second cylindrical component has a hardened outer surface, and the sheet, when it passes between the two cylindrical components is compressed at a specific pressure between 40 and 250 N/mm2. Another subject of the invention is an assembly of steel cylindrical components intended for the manufacture of multiply absorbent sheets.
US08246884B2 Dual cured castable polyurea system for use in golf balls
Compositions for golf balls that include polyurea linkages and that are crosslinked in the soft segments of the polymer backbone. In particular, the compositions of the invention, which are based on a polyurea have improved crosslink density from the crosslinking between the soft, unsaturated segments of the polymer backbone. The curative blend includes at least one isocyanate-reactive component and a free radical initiator.
US08246878B2 Composites comprising a polymer and a layered compound and methods of preparing and using same
A method comprising extrusion compounding a styrenic polymer and a layered compound to produce a composite, and orienting the composite to produce an oriented composite wherein the layered compound comprises natural clay, synthetic clay, natural colloid, synthetic colloid, natural sol, synthetic sol, natural gel, synthetic gel, natural fumes, synthetic fumes, or combinations thereof. A method of preparing an oriented film comprising extrusion compounding a styrenic polymer and a clay to produce a nanocomposite, casting the nanocomposite into a film, and orienting the film in at least one direction.
US08246876B2 Embolization particles and method for making same
In at least one embodiment of the present invention, a method for making embolization particles for occluding fluid flow through a body vessel is provided. The method comprises positioning an elongated body of biocompatible material relative to a cutting device. The elongated body is defined by extrusion of a body cross-section along a longitudinal axis. The elongated body is cut with a cutting device at a plurality of locations along the longitudinal axis to form the embolization particles such that each of the embolization particles has a particle cross-section that corresponds to the body cross-section.
US08246875B2 Process and apparatus for producing thermoplastic resin pellets
An object of the present invention is to provide a process for producing thermoplastic resin pellets, which realizes production of pellets of uniform shape. Another object of the present invention is to provide an apparatus for producing the thermoplastic resin pellets. The invention provides a process for producing thermoplastic resin pellets, including pressurizing the interior of a vessel holding a molten thermoplastic resin, thereby discharging the resin; forming pellets through solidification and cutting of the resin; and transferring the pellets to a storage container via a pipe by a pneumatic transportation or a suction transportation, wherein the amount of the resin discharged is regulated by controlling the pressure in the vessel so that variation in the difference pressure between the inlet and the outlet of the pipe for transferring the pellets is 10% or less.
US08246873B1 Method and system for manufacturing foamed polyolefin tapes at cost effective line speeds
Making foamed polyolefin tapes can include combining a polyolefin resin and a chemical blowing agent to form a mixture. This mixture can then be heated in an extruder to create a supersaturated solution of gas within the polyolefin resin. A cooling device can be positioned adjacent to a die at a set distance for receiving extruded resin and for allowing exposure of the extruded resin to ambient air between a die outlet and the cooling device. This predetermined distance or space between the cooling device and die outlet allows bubbles to grow in the extruded resin and to be shaped such that voids or empty spaces can be generated within the extruded polyolefin resin. The voids or empty spaces allow the formation of tapes which use less material but have adequate strength for various applications, such as for carpet backings, geotextiles, packaging, housewrap, bags, wire insulation, and reinforcement elements in concrete.
US08246871B2 Device and method for the injection molding of a molded part comprising at least one void
The invention relates to a device for the injection moulding of a moulded part (2) comprising a void (1), wherein a projectile (10) can be positioned at a fluid injection nozzle (8) in the region of a fluid aperture (9), which projectile (10) can be caused to flow in the direction of the longitudinal axis (L). To allow the production of moulded parts with enclosed voids in a better way the invention is characterized in that the fluid injection nozzle (8) comprises a section (11) entering into a cavity (5) of a mould, which section (11) is free from any undercut in a direction (E) of insertion of the fluid injection nozzle (8) into the cavity (5), wherein an angle (α) is arranged between a longitudinal axis (L) and the direction (E) of insertion.
US08246869B2 Photo-responsive microencapsulation materials, compositions and methods of use thereof
Photoactivatable prepolymers and methods of use thereof are disclosed for microencapsulation of a substantially water-insoluble material within a nonporous shell. As provided herein, the microencapsulated material is released with no more than a slow release rate. Upon exposure of the nonporous shell to light, the nonporous shell is converted into a porous shell having an increased release rate for the microencapsulated material.
US08246867B2 Method for assembling an optoelectronic device
Methods for assembling an optoelectronic device are provided. The optoelectronic device includes a first transparent substrate, a second substrate, and environmentally sensitive components. The methods comprise the step of applying a fill material to a surface of at least one of the substrates, and lowering a viscosity of the fill material. The methods further comprise the step of pressing the first transparent substrate and the second substrate together such that the fill material substantially fills an area between the first transparent substrate and the second substrate and substantially encapsulates exposed portions of the environmentally sensitive components. The methods still further comprise the step of sealing the first transparent substrate and the second substrate together to hermetically seal the fill material within the area.
US08246866B2 Composition protective against fire and use
Composition protective against fire and use comprising: Water: 25-42% by weight; Ultramarine Blue: 0.015-0.025% by weight; Preservative: 0.09-0.15% by weight; Vegetable Binder: 1.6-2.7% by weight; Spanish White: 6-10% by weight; Calcium Carbonate: 33-56% by weight; Sulphate of Lime: 9-15% by weight, having a dual function, acting as a protective substance against fire as well as a fire-combating substance, such that as protective substance against fire, through application or spraying thereof on a surface to be protected, should it be reached by fire, it acts as protective barrier preventing fire from destroying or damaging it, while as fire-combating substance, through application or spraying thereof on a surface in flames, the fire is quenched and extinguished. The composition is breathable and absolutely wholly ecological, and consequently does not affect plant varieties, permitting the creation of totally effective firebreak “barriers”.
US08246865B2 Process for producing fireproof viscose
The flame retardant viscose is obtained by adding silica to the viscose and subsequently fixing the silica to the fiber, such that the final flame retardant fiber will have regenerated cellulose and a silica polymer providing the fibers with flame retardant properties. Conventionally, the regeneration of the viscose mixture is carried out using zinc sulphate, while the final phase of washing of the fiber is accomplished using sulphuric acid. Both zinc and sulphuric acid are highly contaminating products from the environmental point of view. The invention consists, on the one hand, of replacing the zinc sulphate with aluminum sulphate and, on the other, of replacing the sulphuric acid with hydrogen peroxide or oxygenated water, this minimizing the contaminating effect of the process to an extraordinary extent.
US08246864B2 Flame retardant composition
The ecological flame retardant composition is adapted to protect materials that are flammable. No bromine or borax components are included in the composition. The composition has at least one of i) a mixture of ammonium sulphate and disodium hydrogen phosphate and ii) a mixture of water, ammonium sulphate and disodium hydrogen phosphate.
US08246858B2 Process for inhibiting polymerization of an aromatic vinyl compound
A process for inhibiting polymerization of an aromatic vinyl compound during the stage of producing, purifying, storing or transporting the aromatic vinyl compound which not only inhibits an initial polymerization but also inhibits polymerization efficiently over a long period of time and which is excellent in the handleability. The process involves the step of adding a nitrogenous aromatic compound in combination with a sulfonic acid compound to the aromatic vinyl compound during the production, purification, storage of transportation thereof.
US08246856B2 Highly efficient process for manufacture of exfoliated graphene
A process for preparing oxidized graphite that provides exfoliated graphene, preferably with high surface area. The process uses considerably less chlorate than previously known systems.
US08246851B2 Chiller refrigerants
Disclosed is a nonflammable refrigerant composition consisting of pentafluoroethane in an amount from 62% to 67% based on the weight of the composition, a second component that is selected from 1,1,1,2-tetrafluoroethane, 1,1,2,2-tetrafluoroethane, and mixtures thereof in an amount from 26% to 36% by weight; and an ethylenically unsaturated or saturated hydrocarbon compound that is at least 70% isobutane in an amount of from 1% to 4% by weight and up to 5% by weight based on the weight of the composition of another fluorohydrocarbon. The composition optionally may further include at least one additive, lubricant or combination thereof.
US08246849B2 Magnetic powder production method
To provide a magnetic powder production method, a magnetic sheet production method, and an antenna module production method that are capable of reducing a size of magnetic particles, achieving thinning and a low loss, and improving magnetic permeability without lowering it. At least two oxide-based magnetic materials are mixed, preliminarily calcined, and pulverized. The pulverized magnetic materials are typically formed into a paste by being dispersed in an organic solvent, and the magnetic materials are applied onto a film after being subjected to defoaming processing. Accordingly, a sheet-like magnetic material is formed. The sheet-like magnetic material is cut into predetermined sizes so as to be fragmented into particles, with the result that magnetic particles are formed.
US08246846B1 Method for fabricating integrated MEMS switches and filters
A method for fabricating integrated MEMS switches and filters includes forming cavities in a silicon substrate, metalizing a first pattern on a quartz substrate to form first switch and filter elements, bonding the quartz substrate to the silicon substrate so that the first switch and filter elements are located within one of the cavities, thinning the quartz substrate, forming conductive vias in the quartz substrate, metalizing a second pattern on a second surface of the quartz substrate to form second switch and filter elements, etching the quartz substrate to separate MEMS switches from filters, forming protrusions on a host substrate, metalizing a third metal pattern on the host substrate to form metal anchors and third switch elements, compression bonding the metal anchors on the host substrate to second switch and filter elements, forming signal lines to integrate the MEMS switches and filters and removing the silicon substrate.
US08246845B2 Formation of deep pit areas and use thereof in fabrication of an optic recording medium
A pit is formed from a stack comprising at least one first layer formed by a material able to change physical state and a second layer made of the same material as that forming the first layer, but in a different physical state. An area of the first layer is treated to make said area go from its initial physical state to the physical state corresponding to that of the second layer. A selective etching step is then performed to eliminate said area of the first layer and the area of the second layer initially covered by the treated area of the first layer. Advantageously, said material is a phase transition material.
US08246839B2 Double-walled chamber for ultra violet radiation treatment of liquids
The object of the invention is a double-walled chamber for the UV disinfection of liquids, preferably drinking water and/or waste water. It realizes a rectangular and/or square cross-sectional shape of the UV radiation chamber even at higher pressures, whereby the radiation chamber can moreover be provided with a thin-walled configuration and allows an optimal and close arrangement of UV radiators as compared with a round chamber. By applying the inventive idea, the known dead zones at the entrance are completely eliminated and an entrance turbulence is produced which runs simultaneously with the piston flow in the chamber.
US08246831B2 Digesting and continuously self-cleaning aquarium filter
A method and system for filtering water in aquarium tanks comprising: a macerating/comminuting chamber with a continuously self-cleaning screen covering the discharge outlet that only allows, optimally sized, easily digestible, organic material to pass out of the macerating/comminuting chamber and into an, optionally self-cleaning, media containing denitrifying microbes. There are three different embodiments that use the method of the current invention. These comprise: a reverse flow under-gravel filter apparatus with the macerating/comminuting chamber and filter screen on the discharge side of the pump, a reverse flow under-gravel filter apparatus with the macerating/comminuting chamber and filter screen on the inlet side of the pump, and an external box filter apparatus with the macerating/comminuting chamber on the discharge side of the pump.
US08246830B2 Method and device for removing biological nitrogen and support therefor
Provided is a biological nitrogen removal method which includes, causing to flow a support having, on the surface portion thereof, a two-layered microbial film which holes, in the outer layer, nitrite type nitrifying bacteria or aerobic bacteria and nitrite type nitrifying bacteria as a dominant species and, in the inner layer, anaerobic ammonia oxidizing bacteria as a dominant species while being surrounded with the nitrite type nitrifying bacteria; and thereby carrying out denitrification of the water to be treated by making use of the anaerobic ammonia oxidation reaction. In the biological nitrogen removal method, a feed rate of the support (total surface area of the support per unit capacity of the reaction tank) is adjusted so that an amount of nitrous acid produced by the nitrite type nitrification reaction through the action of the nitrite type nitrifying bacteria reaches a level to inhibit a nitrate type nitrification reaction.
US08246828B2 Methods for selectively producing hydrogen and methane from biomass feedstocks using an anaerobic biological system
The present invention provides a method for selective production of hydrogen and methane from a biomass feedstock in a reactor vessel maintained under anaerobic conditions by controlling moisture concentration in the reactor vessel. The method comprises the steps of introducing a biomass feedstock into the reactor vessel maintained under anaerobic conditions; introducing a bacterial inoculum into the reactor vessel to facilitate digestion of the biomass feedstock; setting a moisture concentration of the contents of the reactor vessel at a first moisture level; and collecting hydrogen gas from the reactor vessel. The method may further comprise maintaining the moisture concentration at a first moisture level or within a first moisture range. The method may additionally comprise increasing the moisture concentration of the contents of the reactor vessel to a second moisture concentration; and collecting methane gas from the reactor vessel. Switching between hydrogen and methane production is controlled by adjusting the moisture concentration of the contents of the reactor vessel.
US08246827B2 Hollow-fiber membrane assembly having the function of preventing the membrane filaments from cracking
A hollow-fiber membrane assembly having the function of preventing the membrane filaments from cracking, which comprises: hollow-fiber membrane filaments (1), protective film(s) (2) and fastening material (3), wherein the protective film (2) enwraps the outside of the hollow-fiber membrane filament(s) (1) near the end head (5), and a portion of the protective film (2) is immobilized in the fastening material (3), while the rest portion of the protective film (2) outside of the fastening material (3) is left free.
US08246822B2 Water treatment apparatus
An apparatus for treating waste water comprises a mixing chamber including mixing members therein for mixing waste water and treatment chemicals therein and a separating chamber at the outlet of the mixing chamber for separating the flocculated contaminants and to provide a supply of clarified water. In a preferred embodiment, the chemicals are injected at sequential locations along an injection tube for sequential mixing of the chemicals with one another in the injection tube prior to the chemicals being injected and mixed into the mixing chamber for mixing with the waste water.
US08246815B2 Methods for regeneration of solvents for extractive processes
An improved solvent regeneration system for extractive distillation and liquid-liquid extraction processes capable of effectively removing heavy hydrocarbons and polymeric materials that otherwise develop in a closed solvent loop. The improved process employs a light hydrocarbon displacement agent, which is at least partially soluble in the solvent to squeeze the heavy hydrocarbons and polymeric materials out of the solvent, with virtually no additional energy requirement. It has been demonstrated that the light non-aromatic hydrocarbons in the raffinate stream generated from the extractive distillation or the liquid-liquid extractive process for aromatic hydrocarbons recovery can displace not only the heavy non-aromatic hydrocarbons but also the heavy aromatic hydrocarbons from the extractive solvent, especially when the aromatic hydrocarbons in the solvent are in the C10+ molecular weight range.
US08246810B2 DNA analysis method and DNA analyzer
Disclosed is a DNA analysis method and a DNA analyzer whose signal intensity is not lowered even when a material at a higher density is measured. There is supplied dATP, dTTP, dGTP, or dCTP from a dATP solution vessel, a dTTP solution vessel, a dGTP solution vessel, or a dCTP solution vessel, and this causes an extension reaction of a double-stranded DNA immobilized to a bead, to yield pyrophosphoric acid. The pyrophosphoric acid is converted into a redox compound by the actions of a reagent and an enzyme contained in a reaction buffer in a reaction buffer vessel. The redox compound causes a variation in surface potential of a measuring electrode bearing an electrochemically active material immobilized thereto through an insulating molecule, and this variation causes a variation in drain current of a field-effect transistor electrically connected to the measuring electrode. Thus, the extension reaction is detected.
US08246808B2 Selective electrochemical deposition of conductive coatings on fuel cell bipolar plates
One exemplary embodiment includes a method of selectively electroplating an electrically conductive coating on portions of a first face of a bipolar plate for use in a proton exchange membrane (PEM) fuel cell. The first face of the bipolar plate defines at least one reactant gas flow channel and a plurality of lands adjacent the at least one channel. The electrically conductive coating may be selectively electroplated on a plurality of first portions of the lands leaving second portions of the lands uncoated by the electrically conductive coating.
US08246805B2 Micro-fluidic chip and flow sending method in micro-fluidic chip
Disclosed herein is a micro-fluidic chip including a hollow area into which a charged droplet is introduced, and an electrode configured to be provided toward the hollow area. Movement direction of a droplet in the hollow area is controlled based on electric force acting between a charge given to the droplet and the electrode.
US08246801B2 Support structure of electroosmotic member, electroosmosis pump, electric power generation apparatus and electronic equipment
Disclosed a support structure of an electroosmotic member including: a support structure; an opening formed in the support member in which an electroosmotic member is disposed; and at least one of an elastic piece to separate the opening and the space from each other and to support the electroosmotic member, a cushioning filled in a gap between a wall of the opening and an edge of the electroosmotic member to support the electroosmotic member, and a projection provided on a wall of the opening to support the electroosmotic member, wherein the elastic piece, the cushioning and the projection supports the electroosmotic member which absorbs an impact or a vibration, and when the impact is applied to the support member (housing), an impact load applied to the electroosmotic member can be suppressed and thus, even when the impact is applied, it is possible to prevent the electroosmotic member from being damaged.
US08246800B2 Gas sensor
A gas sensor for detecting a predetermined gas component in a measurement gas includes a sensor element in which an opening of a first gas inlet and an opening of a second gas inlet for introducing the measurement gas from an outside are provided at one end. The openings are elongated and substantially rectangular. A sum of sizes in a lateral direction of the openings is greater than or equal to 8 μm and less than or equal to 60 μm, and a sum of areas of the openings is greater than or equal to 0.02 mm2 and less than or equal to 0.1 mm2. The sizes in the lateral direction and the areas of the openings are set to be within a preferable range so that the water droplets attached on the forward end surface can be prevented from entering into the sensor element through the openings.
US08246799B2 Devices and methods for analyzing biomolecules and probes bound thereto
Devices and methods for detecting the length of analytes and/or sequencing analytes are provided in which two or more electrical signals are obtained as an analyte traverses a nanopore or fluidic channel. Detection of the relative position of probes hybridized to a biomolecule and/or the length of the analyte (e.g., a biomolecule) rely on detection events to determine a distance associated with the biomolecule. Multiple signals may be obtained (e.g., as functions of time) corresponding to a plurality of detector volumes at known locations along a fluidic channel through which the biomolecule passes, and the distances may be determined from the multiple signals.
US08246798B2 Substrate processing apparatus and apparatus and method of manufacturing magnetic device
According to the present invention, it can be switched whether or not to apply a magnetic field to a substrate depending on a material of a film to be formed, and a magnetic layer and a non-magnetic layer can be formed in the same chamber.A sputtering apparatus 100 includes a substrate holder 102 configured to support a substrate W; magnet holders 106 that are disposed around the substrate holder; magnets 104 that are movably loaded on the magnet holders; supporting members 103 that protrude from the substrate holder so as to face the magnets; connecting members 105 that protrude from the magnets to face the substrate holder; a rotation mechanism 121 configured to rotationally move at least one of the substrate holder and the magnet holders; and a connection switching mechanism 122 configured to move, when positions of the supporting members and the connecting members are matched to each other by rotational movement of the rotation mechanism, the substrate holder upward and downward to engage the supporting members and the connecting members with each other or separate the supporting members and the connecting members from each other, and switch whether or not to apply a magnetic field to the substrate W.
US08246796B2 Fuel cell recharger
An apparatus for recharging a fuel cell cartridge and methods for recharging a fuel cell cartridge are disclosed. An example recharging apparatus may include a housing having a fuel cell cartridge holder. A water reservoir may be disposed in the housing and may have water disposed therein. The recharging apparatus may also include an electrolysis chamber for converting water into hydrogen and oxygen. The electrolysis chamber may be in fluid communication with the water reservoir. The electrolysis chamber may include a hydrogen passage for passing hydrogen from the electrolysis chamber to the fuel cell cartridge holder. The recharging apparatus may further include a vacuum pump at least selectively in fluid communication with the fuel cell cartridge holder. In some instances, the vacuum pump may be used to evacuate residual hydrogen and/or other gases or materials from the fuel cell cartridge and/or determine if the fuel cell cartridge is leaky and requires replacement.
US08246794B2 Method of magnetron sputtering and a method for determining a power modulation compensation function for a power supply applied to a magnetron sputtering source
A method of magnetron sputtering, comprises rotating a magnet of a magnetron with an angular frequency ω, and, during sputtering of material from a source of the magnetron onto a substrate, periodically modulating a power level applied to the source with at least a component comprising a frequency f which is a harmonic of the angular frequency ω of rotation of the magnet other than the first harmonic.
US08246789B2 Hydrous matter treatment system
A treatment system for a watery material that includes: a dewatering tank in which liquefied matter of a material that is gaseous at a normal temperature and a normal pressure is contacted with the watery material and the watery material is separated into the resultant watery material and a liquid phase that contains an aqueous component from the watery material; an evaporator that vaporizes the material that is gaseous at a normal temperature and a normal pressure from the liquid phase; a separator that separates a gas of the material thus vaporized from effluent water; a condenser that condenses the gas into liquefied matter, two or more external heat sources selected from atmosphere, sewage, warm effluent water, and ground water; an external heat temperature detector that detects temperatures of external heats of the external heat sources; and an external heat supply destination controlling unit.
US08246787B2 Solar desalinization plant
A desalinization plant and process utilizes solar radiation to produce steam from seawater which is then used to generate freshwater and electricity.
US08246786B2 Solar desalinization plant
A desalinization plant and process utilizes solar radiation to produce steam from seawater which is then used to generate freshwater and electricity.
US08246785B2 System for applying liquid de-dusting agents to fibrous products
A system and method for applying de-dusting agents to fibrous mats, webs, and/or blankets requiring a lower usage of the de-dusting agents, and producing fibrous products having improved dust suppression are disclosed. The dedusting agent or agents are first reduced to very fine particles or droplets and then, in an air suspension, are passed through the fibrous mat, web and/or blanket to deposit the very fine particles or droplets onto the surfaces of the fibers.
US08246782B2 Apparatus with an impermeable transfer belt in a papermaking machine, and associated methods
An apparatus for transferring a wet paper web from a press nip to a drying cylinder of a papermaking machine, and for structuring the web, includes an impermeable transfer belt that passes through the press nip along with the paper web, and a permeable structuring fabric for transfer of the web onto the drying cylinder, the structuring fabric being arranged in a loop within which a suction transfer device is disposed. A web-contacting surface of the belt has a non-uniform distribution of microscopic-scale depressions, and a suction zone of the transfer device includes a transfer point spaced a distance D from the press nip. The belt is arranged to bring the web into contact with the structuring fabric in the suction zone for a length L, such that suction is exerted on the paper web to transfer the paper web from the belt onto the structuring fabric at the transfer point.
US08246780B2 Methods for enhancing brightness and resistance to thermal yellowing of bleached kraft pulp and paper
Compositions and processes that preserve and enhance the brightness and improve color of pulp or paper when applied during different stages of the papermaking process are identified. The composition and method maintains and/or enhances brightness, prevent yellowing, and enhances the performance of paper products. Used in combination with optical brighteners and/or chelants the described agents produce a synergistic effect not previously identified in the paper process.
US08246779B2 Maintenance of sulfur concentration in Kraft pulp processes
Methods and apparatus for maintaining sulfur concentration in the chemical recovery cycle of a Kraft pulping process. A portion of the recovery boiler ash is dissolved, treated to remove solids, and combined with an acid to provide a solution. The recovery boiler ash may be dissolved directly in the acid. The acid may be effluent from a chlorine dioxide generator. The resulting solution is maintained in a fully dissolved state and subjected to an acid separation step to provide a sodium sulfate enriched phase, which may be used to maintain sulfur concentration in the Kraft pulping process, and a sulfuric acid phase. Chlorine ions can be separated with the sulfuric acid phase. The sulfuric acid phase can be recycled to the chlorine dioxide generator.
US08246777B2 Honeycomb sandwich panels and the use of a two component polyurethane adhesive in the manufacture thereof
The present invention relates to the manufacturing of honeycomb sandwich panels. Particularly a two component polyurethane adhesive having a Polyol P1 with a bisphenol-A or bisphenol-F moiety in its structure, a polyester or polyether Polyol P2, a heat-activated polyurethane catalyst CA and a polyisocyanate PI. The adhesive is remarkably well suited for the manufacturing of honeycomb sandwich panels showing particularly a short curing time combined with a long open time and good wetting and bonding properties.
US08246776B2 Crank for bicycle and method for manufacturing the same
Disclosed are a method for manufacturing a crank for a bicycle by bonding structural members to each other with an adhesive comprising; a step for applying the adhesive in a line-like or dot-like form in correspondence with an intervention region of the adhesive; a step for disposing a fabric in correspondence with the intervention region of the adhesive; a step for expanding the adhesive applied in a line-like or dot-like form in the fabric; and a step for bonding the structural members to each other with the adhesive expanded in the fabric, and a crank for a bicycle manufactured by the method. When the crank for a bicycle is manufactured by bonding the structural members to each other with the adhesive, the adhesive can be applied easily at a high accuracy and a good repeatability, variations of application condition and amount of used adhesive can be suppressed, and variation in quality can be suppressed.
US08246774B2 Resin bonding method by photoirradiation, method for producing resin article, resin article produced by the same method, method for producing microchip, and microchip produced by the same method
A resin bonding method according to the present invention is a resin bonding method for bonding a first resin and a second resin including (I) a step of irradiating spaces containing oxygen molecules with vacuum ultraviolet light having a wavelength of 175 nm or less, the spaces being in contact with surfaces of the first and second resins; and (II) a step of, after the irradiation, subjecting the surfaces to temperature rise while the surfaces are in contact with each other, to bond the first resin and the second resin together with the surfaces serving as bonding surfaces. In the step (I), the surfaces of the first and second resins may be further irradiated with the vacuum ultraviolet light. In this case, a light amount of the vacuum ultraviolet light having reached the surfaces is preferably, for example, 0.1 J/cm2 or more and 10 J/cm2 or less.
US08246771B2 Filtering screen
A method of manufacturing two screens in a jig by laying a length of woven wire cloth across two rectangular frames laid side by side in the jig with longer edges abutting, and orientating the cloth so that the warp wires extend continuously across the two screens. The cloth is tensioned and bonded to the frames after which it is severed along the join and surplus cloth is trimmed away from the edges of the frame. If the cloth has a square mesh and the warp wires are of greater cross-section than the weft wires, the warp wires will extend across the width of the frame, and if the cloth has a rectangular mesh, the greater number of warp wires per unit length also extends across the width of the frame. In each case warp wires will resist the stresses across the width of the central region of each opening.
US08246770B2 Copper grid repair technique for lightning strike protection
A method for reworking an electrically conductive layer of a composite skin is disclosed in which a patch replaces the altered section of the electrically conductive layer. The method is performed by removing a portion of the electrically conductive layer to reveal the underlying composite skin. A patch is formed, having an electrically conductive section coupled to an adhesive having a low dielectric breakdown strength, and is then introduced over the underlying composite skin such that the adhesive layer covers the underlying composite skin and overlaps an unremoved portion of the electrically conductive layer. The patch is applied such that the electrically conductive section within the patch covers the adhesive layer and overlaps the unremoved section of the electrically conductive layer. The adhesive layer preferably has a low dielectric breakdown strength, so that electricity from lightning which strikes the composite skin may be conducted through the adhesive.
US08246766B2 High-strength Ni-based alloy tube for nuclear power use and method for manufacturing the same
The high-strength Ni-based alloy tube for nuclear power use consists, by mass percent, of C: 0.04% or less, Si: 0.10 to 0.50%, Mn: 0.05 to 0.50%, Ni: 55 to 70%, Cr: more than 26% and not more than 35%, Al: 0.005 to 0.5%, N: 0.02 to 0.10%, and one or more kinds of Ti: 0.01 to 0.5% and Nb: 0.02 to 1.0%, the balance being Fe and impurities. For this alloy tube, the grain size is as fine as grain size No. 6 or higher in JIS G 0551. It is preferable that the high-strength Ni-based alloy tube be manufactured by the process of preparing a Ni-based alloy stock through a remelting process, hot forging, heating to 1000 to 1160° C., hot extruding at a working ratio such that an extrusion ratio is 4 or higher, and performing solution annealing and thermal treatment.
US08246763B2 High strength aluminum alloy casting and method of production of same
A high strength aluminum alloy casting obtained by casting an aluminum alloy comprised of 7.5 to 11.5 wt % of Si, 3.8 to 4.8 wt % of Cu, 0.45 to 0.65 wt % of Mg, 0.4 to 0.7 wt % of Fe, 0.35 to 0.45 wt % of Mn, and the balance of Al and not more than 0.2 wt % of unavoidable impurities, wherein this aluminum alloy has 0.1 to 0.3 wt % of Ag added to it or contains 0.1 to 1.0 wt % of at least one element selected from the group of second additive elements comprised of Rb, K, Ba, Sr, Zr, Nb, Ta, V, and Pd and rare earth elements, and a method of production of a high strength aluminum alloy casting comprising the steps of filling a melt of an aluminum alloy in a mold to obtain a casting, taking out the aluminum alloy casting from the mold, solubilizing the high strength aluminum alloy casting by heating in a temperature range of 495 to 505° C. for 2 to 6 hours, quenching the high strength aluminum alloy casting after the solubilization, and age hardening the high strength aluminum alloy casting by heating in a temperature range of 160 to 220° C. for 2 to 6 hours after quenching.
US08246762B2 Implantable medical devices comprising bio-degradable alloys
The invention provides medical devices comprising high-strength alloys which degrade over time in the body of a human or animal, at controlled degradation rates, without generating emboli. In one embodiment the alloy is formed into a bone fixation device such as an anchor, screw, plate, support or rod. In another embodiment the alloy is formed into a tissue fastening device such as staple. In yet another embodiment, the alloy is formed into a dental implant or a stent.
US08246754B2 Process for removing ink from printed substrate
A process for removing ink from a printed media substrate. Such process includes the step of providing a media substrate including an ink printed image wherein the ink composition or the media substrate contains photolabile entities. Then the process includes the step of applying UV light on the printed substrate wherein the emitted UV light has a wavelength value which is below the threshold wavelength of the photolabile entities.
US08246753B2 Gaspath cleaning system
A method for cleaning a jet engine comprises storing fluid comprising water in a water holding tank. The water is heated to create heated fluid. The let engine desired to be cleaned is at least partially covered with a waterproof cover, and a J-hook is inserted into the jet engine and affixed to a front compressor stator of a second compressor stage of the jet engine. An input hose is coupled between the storage tank and the waterproof cover and the J-hook is coupled to the input hose. The heated fluid is injected into the jet engine via the input hose and J-hook, which directs the heated fluid inside the jet engine. The resultant effluent is collected in the waterproof cover.
US08246752B2 Methods and devices to clear obstructions from medical tubes
A device for clearing obstructions from a medical tube, such as a chest tube, is disclosed in various embodiments. In embodiments, the device features a guide wire that extends from a drainage canister and can be advanced and withdrawn through a medical tube, such as a chest tube, via an actuator. The guide wire is actuated so as to maintain the sterile field within the chest tube and the associated suction pathway. Methods of clearing a medical tube of obstructions using such a device are also disclosed.
US08246751B2 Pulsed detonation cleaning systems and methods
The present application provides a pulsed detonation cleaning system for cleaning an enclosed structure. The pulsed detonation cleaning system may include a pulsed detonation combustor cleaner and an external fuel-air flow. The pulsed detonation combustor cleaner delivers the external fuel-air flow into the enclosed structure and ignites the external fuel-air flow to clean the enclosed structure.
US08246750B2 Apparatus and method for hydrolysis of cellulosic material in a multi-step process to produce C5 and C6 sugars using a single vessel
A system and method for extracting C5 sugars including pentose and/or C6 sugars including hexose from a slurry of cellulosic material comprising cellulose, water, and optionally acid.
US08246748B2 Method and apparatus for coating surfaces
A workpiece support member can rotate about an axis relative to a source, and the source can emit a plume of coating material that flows toward the workpiece support member approximately parallel to the axis. A plume-influencing shield can rotate with the workpiece support member, and has a plurality of openings extending therethrough approximately parallel to the general direction of flow of the plume. According to a different aspect, a method involves: rotating a workpiece support member about an axis relative to a source; emitting from the source a plume of coating material that flows toward the workpiece support member approximately parallel to the axis; and influencing the plume with structure that includes a shield rotating with the workpiece support member, the shield having a plurality of openings extending therethrough approximately parallel to the general direction of flow of the plume.
US08246747B2 Apparatus for manufacturing semiconductor
Disclosed is an apparatus for manufacturing semiconductors, to be used for various processes in semiconductor manufacture processing, such as the forming of layers on wafers. A tube has a processing space therein and a discharge hole at a side thereof. A boat can be loaded and unloaded through a lower opening of the tube. Susceptors are vertically separated from one another and supported within the boat, have a central hole defined in the respective centers of rotation thereof, and have a plurality of wafers stacked around a central perimeter on the respective top surfaces thereof. A supply tube is installed at the top of the boat and passes through each central hole of the susceptors, and defines discharge holes for discharging processing gas supplied from the outside onto each top surface of the susceptors.
US08246746B2 Laser uses for single-crystal CVD diamond
The present invention is directed to new laser-related uses for single-crystal diamonds produced by chemical vapor deposition. One such use is as a heat sink for a laser; another such use is as a frequency converter. The invention is also directed to a χ(3) nonlinear crystalline material for Raman laser converters comprising single crystal diamond.
US08246744B2 Method for predicting precipitation behavior of oxygen in silicon single crystal, method for determining production parameter of silicon single crystal, and storage medium for storing program for predicting precipitation behavior of oxygen in silicon single crystal
By specifying an initial oxygen concentration in a silicon single crystal and a concentration of thermal donors produced according to a thermal history from 400° C. to 550° C. that the silicon single crystal undergoes during crystal growth, a nucleation rate of oxygen precipitates produced in the silicon single crystal while the silicon single crystal is subjected to a heat treatment is determined. Further, by specifying the heat treatment condition of the silicon single crystal, an oxygen precipitate density and an amount of precipitated oxygen under a given heat treatment condition are predicted by calculation.
US08246743B2 Single crystal silicon carbide nanowire, method of preparation thereof, and filter comprising the same
Single-crystal silicon carbide nanowires and a method for producing the nanowires are provided. The single-crystal silicon carbide nanowires have a very high aspect ratio and can be used for the fabrication of nanoelectronic devices, including electron gun emitters and MEMS probe tips, for use in a variety of displays and analyzers. Further provided is a filter comprising the nanowires. The filter is applied to systems for filtering vehicle engine exhaust gases to achieve improved filtering performance and increased lifetime.
US08246741B2 Composition and its use for improving the processibility of hydraulically setting compositions
The invention relates to a composition comprising at least one plasticizer for a hydraulically setting composition and at least one polyalkylene glycol. The invention also relates to a process that uses the composition for improving the processibility, in particular for extending the processing time, of hydraulically setting compositions.
US08246739B2 Concrete with a low clinker content
A process for the preparation of a wet concrete composition, including mixing Portland clinker in the form of grains having a Dv97 from 10 to 30 μm or having a Blaine specific surface greater than or equal to 5300 cm2/g; slag; calcium sulphate; complementary materials, having a Dv90 less than or equal to 200 μm; from 1500 to 2200 kg/m3 of aggregates; a plasticizer; optionally an accelerator and/or an air-entraining agent and/or a thickening agent and/or a retarder and/or a clay-inerting agent; with 140 to 220 l/m3 of effective water, the total quantity of clinker in the wet concrete being less than or equal to 200 kg/m3.
US08246734B2 Writing ink composition
The writing ink composition of the present invention includes: an oil-based component containing a polar solvent and a spinnability imparting agent; and a water-based component containing water, polyhydric alcohol, a thixotropy imparting agent and a pigment, the water-based component being dispersed in the above oil-based component.
US08246732B2 Exhaust gas cleaning apparatus
An exhaust gas cleaning apparatus according to the present invention includes a wall member configured to form a gas passage for allowing an exhaust gas to pass therethrough, and a mist nozzle and a water film nozzle disposed in the gas passage. The mist nozzle forms mist in the gas passage, and the water film nozzle forms water film in the gas passage. The mist nozzle is disposed further toward the upstream side in a flowing direction of the exhaust gas than the water film nozzle. Plural sets of the mist nozzle and the water film nozzle may be provided.
US08246726B2 Ventilation member
A ventilation member (1A) includes: a gas permeable membrane (2); a support body (3) for supporting the gas permeable membrane (2); and a sealing element (4). The support body (3) has: a main portion (31) having a front surface (31a) on which the gas permeable membrane (2) is attached and a back surface (31b) for pressing the sealing element (4) against a housing (6); and a plurality of leg portions (32) to be inserted into an opening (61) and each having a hook (33) at its end. The main portion (31) has, at positions corresponding to the hooks (33) in the direction in which the leg portions (32) are inserted, through-holes (37) through which the hooks (33) are exposed as seen from the side of the front surface (31a) of the main portion (31).
US08246724B2 Method for air treatment in a display cabinet and cabinet for implementing the method
In a method for air treatment in a display cabinet for the storage and/or display of objects, whose walls, floor and roof structure more or less enclose the inside space of the display cabinet and in which a forced inflow of air from an air delivery system connected to the inside space (1) of the cabinet maintains a slight excess pressure compared with the air outside it, the said airflow passes through suitable dust or gas filtration means before entering the cabinet and its air humidity is adjusted and/or controlled by means of a cooling device. After filtration, the airflow passes through a catalyser (8) present in a liquid (7), the air picks up moisture from the liquid and is rendered completely free from germs. In this manner and in a simple way, a completely germ-free atmosphere is produced inside the display cabinet. A display cabinet for implementing the method has a corresponding structure.
US08246719B2 Use of impure inert gases in the controlled heating and cooling of mixed conducting metal oxide materials
Method for processing an article comprising mixed conducting metal oxide material. The method comprises contacting the article with an oxygen-containing gas and either reducing the temperature of the oxygen-containing gas during a cooling period or increasing the temperature of the oxygen-containing gas during a heating period; during the cooling period, reducing the oxygen activity in the oxygen-containing gas during at least a portion of the cooling period and increasing the rate at which the temperature of the oxygen-containing gas is reduced during at least a portion of the cooling period; and during the heating period, increasing the oxygen activity in the oxygen-containing gas during at least a portion of the heating period and decreasing the rate at which the temperature of the oxygen-containing gas is increased during at least a portion of the heating period.
US08246717B1 Process for the recovery of metals from used nickel/metal hydride batteries
The present invention provides a process of recovering AB5 and/or AB2 as well as other metals from spent nickel metal hydride batteries from a slury by a series of separation steps utilizing the screening off of larger metal particles, removal of magnetizable small metal particles from a filter and then separating AB5 and/or AB2 by passing the filtrate through a froth flotation step to separate AB5 and/or AB2 from lighter small particles.
US08246715B2 Adjustable vortexer apparatus
A method of adjusting a vortex of molten metal comprises providing a scrap charging vessel. The scrap charging vessel includes a vortex control plate having an outlet orifice that can be positioned at a bottom of the vessel so that the outlet orifice is in fluid communication with an outlet passageway of the vessel. A vortex level is estimated or observed. A size of the outlet orifice of the vortex control plate is selected that can produce a desired level of a vortex in the vessel that is the same as or different than the estimated or observed vortex level. The vortex control plate of the selected outlet orifice size is positioned in the vessel. Molten metal is moved into an inlet opening of the vessel and forms the vortex at the desired level in the vessel.
US08246711B2 Fertilizers and methods for using biotic science to feed soils
Biotic fertilizers are described that build soil nutrients by accelerating the growth of topsoil microorganisms Biotic fertilizers are primarily aimed at increasing populations of cyanobacteria, formally known as blue-green algae, and like organisms that have the ability to engage in photosynthesis reand to engage in the extraction of nitrogen from the atmosphere. Methods of biotic fertilizer manufacture are presented that utilize animal waste product as well as desirable compositions obtained thereby.
US08246708B2 Filter arrangement; sealing system; and methods
A filter pack includes a filter construction and a sealing system for sealing the construction within a duct or housing. The filter construction has first and second opposite flow faces and is configured for a straight-through flow. The sealing system includes a frame construction and a compressible seal member. The compressible seal member is molded around a portion of the frame construction. The compressible seal member is sufficiently compressible to form a radial seal between and against the frame construction and a surface of a housing when the filter pack is inserted within the housing.
US08246696B2 Cleaning compositions employing extended chain anionic surfactants
The invention discloses synergistic combinations of surfactants blends and cleaning composition. In certain embodiments a surfactant system is disclosed which includes extended anionic surfactants, linker surfactants, and a multiply charged cation component. This system forms emulsions with, and can remove greasy and oily stains, even those comprised of non-trans fats. The compositions may be used alone, as a pre-spotter or other pre-treatment or as a part of a soft surface or hard surface cleaning composition.
US08246694B2 Prosthetic locking liner with improved knee flexion
A prosthesis comprising an elastomeric locking liner sized and configured to surround a limb of a patient about a knee joint, the liner having an inner surface for facing the limb of the patient and an outer surface defining an anterior region and a posterior region which are demarcated by an imaginary plane extending midway between the front most portion and rear most portion of the limb along the length of the limb, wherein the anterior region has an anterior material secured thereto and the posterior region has a posterior material secured thereto and the anterior and posterior materials having equal transverse elongation, and the anterior material having a longitudinal elongation greater than the longitudinal elongation of said posterior material, whereby when said prosthesis is donned onto a limb of a patient over the knee and the limb is flexed about the knee, buckling of the prosthesis about the knee is substantially reduced or eliminated and wherein the distal end of the liner includes an insert member adapted to receive a connector for locking the liner to a prosthetic socket when worn on a residual limb of an amputee.
US08246691B2 Stent
A bioabsorable stent is disclosed. The stent is made of a bioabsorable material and has an elongated body having a proximate end, a distal end, and at least one open channel formed on the exterior surface of the elongated body to provide fluid communication between the proximal end and the distal end. Also disclosed is a bioabsorable stent having an elongated center rod having a proximate end and a distal end and a plurality of leaflets extending outward from the center rod and forming channels between two neighboring leaflets to provide fluid communication between the proximal end and the distal end.
US08246690B2 Stent with soluble bladder retention member
Ureteral stents having at least a portion of a proximal end of the ureteral stent constructed with a material that dissolves after being exposed to a bodily fluid for a period of time are disclosed herein. At least a portion of the proximal end portion of the elongate member includes a dissolving portion configured to dissolve in response to being exposed to a bodily fluid for a period of time. The elongate member also includes a non-dissolving portion that includes the entire retention member of the distal end portion and is substantially stable in the bodily fluid of the urinary tract of the patient. In some embodiments, a medial portion of the ureteral stent is also constructed with one or more dissolving materials. In some implementations, the proximal and/or the medial portions of the ureteral stent are constructed using various combinations of dissolving and non-dissolving materials.
US08246689B2 Ureteral stent for improved patient comfort
A ureteral stent for assisting the movement of urine along a patient's ureter and into the patient's bladder. The stent includes an elongated tubular segment extending toward the bladder from a kidney end region for placement in the renal cavity to a bladder end region. A central lumen connects at least one opening at the first end region to at least one opening in the bladder end region. Thin flexible tail(s) are attached to the bladder end region of the tubular segment at a point outside the bladder so as to receive urine from the opening in the bladder end region of the tubular segment and to transport urine from there across the ureter/bladder junction and into the bladder. The tails include an elongated external urine-transport surface sized and configured to transport urine along the ureter. The urine transporting surface(s) are sized and configured to extend along at least part of the ureter, across the ureter/bladder junction, and from there into the bladder. In some embodiments, the distal region includes a tubular body with a lumen in fluid communication with an interstitial area defined by one or more flexible filaments of the proximal region forming at least one loop.
US08246688B2 Knee endoprosthesis
In a knee endoprosthesis comprising a tibia part, a femur part having two condylar surfaces, and a meniscus part arranged between the femur part and the tibia part, the meniscus part having on its upper side two bearing shells for receiving and mounting the condylar surfaces of the femur part and having on its underside a meniscus-bearing surface which rests in a displaceable manner on a tibia-bearing surface on the upper side of the tibia part, in order to allow as large a bending angle as possible, with best possible adaptation to the anatomy of the natural knee joint, it is proposed that the meniscus-bearing surface and the tibia-bearing surface each have a spherical projection or a spherical recess offset in a medial or a lateral direction in relation to their center, that the spherical projection on one of the two bearing surfaces engage the spherical recess of the other bearing surface and thereby form a ball bearing-like mounting of the meniscus part on the tibia part, and that in the lateral or medial part of the two bearing surfaces, these bearing surfaces form supporting areas bearing on each other, which are curved in a dorsal-ventral direction and have a radius of curvature there, which is greater than the radius of curvature of the spherical projection and the spherical recess by at least the factor 2.5.
US08246687B2 Shoulder prosthetic
A shoulder implant assembly including a humeral stem, a head, a cup, and a taper adaptor. The humeral stem is configured to be inserted into a humerus bone. The head includes a metal substrate having a coupling taper and a polymeric cover mounted to the metal substrate having a convex outer surface and a generally planar base. The cup has a concave surface configured to articulate with the polymeric cover of the head. The taper adaptor is configured to mate with the coupling taper of the head. The taper adaptor is configured to connect the head to the stem when the cup is connected to a glenoid. The taper adaptor is configured to connect the head to the glenoid when the cup is connected to the humeral stem.
US08246686B1 Systems and methods for spinal fusion
A system and method for spinal fusion comprising a spinal fusion implant of non-bone construction releasably coupled to an insertion instrument dimensioned to introduce the spinal fusion implant into any of a variety of spinal target sites.
US08246682B2 Methods and devices for expanding a spinal canal using balloons
An in-situ formed laminoplasty implant comprising an expandable bag containing a flowable, hardenable composition, wherein the implant may be shaped to act as a laminoplasty strut and be rigidly connected to a prepared lamina space.
US08246680B2 Patient-specific spinal implants and related systems and methods
Methods and systems for generating custom implants by programmatically analyzing a patient's image data to electronically obtain shapes and dimensions of relevant anatomical features of a target region of the patient; and fabricating a patient-specific replacement implant for the patient using the analyzed patient image data. Related patient-specific spinal implants are also described.
US08246678B2 Methods and apparatus for endovascularly replacing a patient's heart valve
The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an anchor having an expandable braid. In some embodiments, the expandable braid is fabricated from a single strand of wire. In some embodiments, the expandable braid comprises at least one turn feature. The anchor and the valve preferably are configured for endovascular delivery and deployment.
US08246677B2 Delivery systems and methods of implantation for replacement prosthetic heart valves
A method of delivering a replacement prosthetic valve to a previously implanted prosthetic valve including the steps of compressing a replacement prosthetic valve having an expandable stent within a sheath of a delivery system, wherein the delivery system comprises a proximal end, a distal end, and a centering structure positioned between the proximal and distal ends, advancing the delivery system and compressed replacement prosthetic valve into a vessel of a patient until the distal end of the delivery system is positioned adjacent to a second side of a previously implanted prosthetic valve, deploying the centering structure to radially reposition the distal end of the delivery system, further advancing the delivery system toward the previously implanted prosthetic valve, and deploying the replacement prosthetic valve.
US08246676B2 Implantable venous valve
A venous valve prosthesis includes a hollow conduit (40) defining a central passageway through which blood may flow. Opposing, pliable leaflet members (30) are located within the conduit and move back and forth between a first, open position, whereby blood may flow through the central passageway in a first direction, and a second, closed position, whereby blood is prevented from backflowing through the central passageway in a second direction which is opposite the first direction. A hollow and generally cylindrical support member (10, 20) retains the leaflet members and is coaxially disposed within the conduit. The support member includes opposing cutaway regions (18) defining two axially extending struts (16) supporting the leaflet members. The cutaway regions, in cooperation with the struts, allow the leaflet members to collapse inwardly to the closed position.
US08246665B2 Posterior cervical cross connector assemblies
A spinal cross connector head assembly and a cross connector assembly utilizing the spinal cross connector head assembly are configured for fixation to an existing spinal rod bone screw head. The spinal cross connector head assembly has one or more components which incorporate one or more breakaway portions that aid in the installation of the cross connector head assembly onto a polyaxial spinal rod bone screw assembly. The spinal cross connector assembly includes first and second spinal cross connector head assemblies each of which is configured for fixation to existing, adjacent spinal rod screw heads and connection with a cross connector rod. Each spinal cross connector rod head assembly has a dual breakaway system including a cross connector head component having a breakaway collar that, once detached, provides a polyaxial cross connector head, and a set screw component having a breakaway set screw that, once detached, provides fixation of the orientation of the polyaxial cross connector head relative to the polyaxial spinal rod bone screw head.
US08246659B2 Installation systems for spinal stabilization system and related methods
A system for implantation of a spinal stabilization system includes a vertebral anchor having a top portion. The top portion has a perimeter and a first engaging element. The first engaging element has a first longitudinal axis that is generally parallel to a second longitudinal axis of the top portion. The perimeter extends around the second longitudinal axis. The system also includes a driving tool that has a second engaging element that is configured to cooperate with the first engaging element to substantially restrict rotation of the driving tool relative to the top portion about the second longitudinal axis. The first engaging element is configured to slidably receive the second engaging element in a direction along the first longitudinal axis, and the second engaging element is configured to extend substantially within the perimeter of the top portion.
US08246655B2 Intervertebral implant devices and methods for insertion thereof
Implant apparatuses are provided for being inserted between adjacent vertebral bone portions and maintaining mechanical engagement with the vertebral bone portions. The implant apparatuses are generally constructed to be inserted in an insertion orientation and pivoted between the vertebral bone portions to an implanted orientation. The implant apparatuses are further secured in the implanted orientation to maintain engagement with the adjacent vertebral bone portions.
US08246654B2 Transfacet fixation assembly and related surgical methods
The present invention provides a transfacet fixation assembly, including: an engaging bolt; and a receiving bolt selectively coupled to and engaged with the engaging bolt at an angle of between about 30 degrees and about 120 degrees; wherein each of the engaging bolt and the receiving bolt is configured to be disposed through a hole or bore formed through one of a plurality of bony structures making up a portion of a facet joint of a spine. Optionally, the engaging bolt includes a spherical distal end for engaging a locking sleeve disposed at a distal end of the receiving bolt.
US08246651B2 Removable vena cava filter for reduced trauma in collapsed configuration
The present invention provides a method of capturing thrombi in a blood vessel, which includes delivering a removable filter in a collapsed state within the blood vessel and deploying the filter to an expanded state within the blood vessel. The filter includes a plurality of primary struts and a plurality of secondary struts emanating from a hub and extending arcuately along a longitudinal axis and linearly radially. Each primary strut has an arcuate segment including first and second curved portions. Each secondary strut includes first and second arcs. The primary struts terminate with an anchoring hook. Each primary strut crosses another primary strut along the longitudinal axis in the collapsed state such that the arcuate segments occupy a first diameter and the anchoring hooks occupy a second diameter, the first diameter being greater than the second diameter for filter retrieval or delivery. In the expanded state, the secondary struts centralize the filter in the blood vessel and the anchoring hooks engage with the blood vessel.
US08246650B2 Removable vena cava filter
A removable filter for capturing thrombi in a blood vessel. The filter comprises a plurality of primary struts having first ends connected to each other to define a central axis of the filter. Each primary strut has a curved member extending from the central axis and terminates at an anchoring hook to engage the blood vessel at a first axial plane. The filter further comprises a plurality of secondary struts connected to the curved members of the primary struts and extending therefrom to a free end at a second axial plane to centralize the filter in the blood vessel.
US08246648B2 Removable vena cava filter with improved leg
A removable filter for capturing thrombi in a blood vessel. The filter has primary struts with first ends attached together along a longitudinal axis. Each primary strut has a body member extending from its first end along the longitudinal axis to an anchoring hook. Each primary strut is configured to move relative to the longitudinal axis between an expanded state and a collapsed state. At least one primary strut has a resistant portion next to the anchoring hook. The resistant portion is configured to contact the blood vessel in the expanded state. The filter also has secondary struts. The secondary struts have proximal ends attached together along the longitudinal axis and distal ends located radially from the longitudinal axis in the expanded state. The secondary struts are configured to engage the blood vessel to centralize the filter in the expanded state in the blood vessel.
US08246641B2 Thrombus removal device
A thrombus removal device includes a shaft with a distal end and a proximal end, a sheath with a distal end and a proximal end, and a helical coil attached at a proximal end to the distal end of the shaft and is disposed within the lumen of the sheath in a closed configuration. The helical coil includes a plurality of body portions with turns spaced apart longitudinally and laterally to facilitate screwing the helical coil into a thrombus and also providing an open area into which the thrombus can be captured. A distal tip of the helical coil is provided with a loop, an angle of which is about the same as the angle of at least one body portion. The helical coil assumes an open configuration when the sheath is retracted proximally from the distal tip. An aspiration device may be provided in fluid communication with the center of the helical coil.
US08246640B2 Methods and devices for cutting tissue at a vascular location
A tissue cutting device includes a sizing element which detects the diameter of the vessel in which the cutting device is positioned. The sizing element is coupled to the cutting element so that the amount of the cutting element that is exposed varies in response to movement of the sizing element.
US08246639B2 Atraumatic clamp
A device for clamping a tissue, the device having a clamp (100) with at least one magnetic portion. In at least one embodiment, the clamp (100) has two oppositely polarized magnets (102, 104) and a mounting structure (106) for the magnets. In some other embodiments, a clamp has an electromagnetic collar (500) and a power source (300) to provide power to the collar (500) via an electrical connector (302). In at least some embodiments, the clamps (100) may also be electromagnetic.
US08246631B2 Two stage plunger for intraocular lens injector
A plunger for an IOL injector device includes a shaft with a distal tip and a compressible sleeve positioned about the shaft with the tip extending forwardly of the sleeve. In a first stage of IOL advancement through the injector device, the plunger tip engages and pushes the IOL through a first section of the injector body. In a second stage of IOL advancement, the sleeve enters the narrowing section of the injector body toward the open tip thereof with the IOL and sleeve both undergoing compression. The sleeve compresses and lengthens in a forward direction ultimately enveloping the plunger distal tip. Viscoelastic applied inside the injector accumulates between the leading edge of the compressed sleeve and the compressed IOL thereby creating hydraulic pressure which pushes the compressed IOL through the remainder of the injector body and out the open distal tip thereof.
US08246628B2 Apparatus for delivery of reinforcing materials to bone
An apparatus and methods for delivery of reinforcing materials to a weakened or fractured bone is disclosed. An apparatus for delivering a reinforcing mixture to a bone including a tube having a proximal end, a distal end, and a longitudinal axis therebetween, wherein the tube has at least one inner lumen capable of allowing a bone reinforcing mixture to pass therethrough; a balloon engaging the tube wherein the balloon expands from a substantially deflated state to a substantially inflated state upon the bone reinforcing mixture entering the balloon; and at least one light guide extending through the tube into the balloon to guide a light into the balloon.
US08246625B2 Reducing instrument for spinal surgery
An instrument is provided for reduction of a rod or other elongated member into an implant, such as a bone screw. In one embodiment, such an instrument includes a rod adjusting assembly pivotably attached to an implant holding assembly. The implant holding assembly can be pivotably connected to an implant, and the rod adjusting assembly is operable to move a rod toward or away from the implant holding assembly. In that embodiment, several motions are possible by the instrument so that relatively small or large movements of a rod with respect to an implant may be made.
US08246622B2 Tool and corresponding method for removal of material from within a body
A device for removing material from within the body, includes an elongated element formed from hollow segments sequentially interconnected at effective hinges. The device assumes an insertion configuration for insertion of the segments sequentially through an opening of a first dimension into the body. A portion of the elongated element inserted into the body progressively assumes a material removing configuration in which a relative position of each segment relative to an adjacent segment is delineated by the effective hinge together with additional abutment surfaces defining a fully deflected state of the effective hinge. The material removing configuration has at least two dimensions exceeding the first dimension. At least two of the segments are formed with at least one cutting configuration deployed so as to collect material into a hollow volume of the segment during progressive formation of the material removing configuration as the elongated element is advanced.
US08246620B2 Advanced burr, applique for a burr and method of fabricating
An abrading device including an advanced burr and appliqué for a burr and a new process for making cutting tools for fine material removal applications such as in bone and tissue surgeries. An appliqué sheet is first engineered by CAD with an abrading surface having cutting facets. The appliqué is attached to a surface of a tool blank and then metallurgically bonded and coated by the BRAZOL® or Co—P process. The tool blank has a proximal shank attachable to a driver and a distal surface to which the appliqué is affixed. Since each facet is attached to surrounding facets and then strongly bonded to the tool, the facets do not dislodge when used to abrade a surface of an object. The BRAZOL® or Co—P coating imparts excellent wear resistance and lubricity to the cutting facets. This results in excellent operational and material removal characteristics. This approach to making surgical and fine industrial tools offers engineered flexibility in design rather than process dependent designs.
US08246618B2 Electrosurgical jaws with offset knife
An endoscopic forceps includes a housing having a shaft attached thereto with a longitudinal axis defined therethrough and an end effector assembly disposed at a distal end thereof. The end effector assembly includes first and second jaw members disposed in opposing relation relative to one another and moveable from a first, open position to a second, closed position for grasping tissue therebetween. Each of the jaw members includes a proximal flange adapted to communicate with a drive assembly for moving the jaw members between the first and second positions. One or both of the of the jaw members has a curved knife channel defined therein having a proximal end that is offset from the longitudinal axis defined through the shaft. A knife guide is assembled to an outer surface of one of the proximal flanges of the jaw members on the same side as the proximal end of the knife channel and defines a knife path therein configured to guide a knife into the knife channel for translation therethrough.
US08246613B2 Method and apparatus of treating tissue
A method for the treatment of skin including the steps of determining the skin depth for energy absorption necessary for treatment; and generating a spot size for energy impinging on the skin to provide a desired amount of energy to the desired depth for treatment. In one embodiment the selected spot size has a small diameter. In another embodiment the spot diameter is narrower than the spacing between adjacent hairs on the skin. In another aspect the invention relates to an apparatus for the treatment of skin including a source of energy; and a means for selecting a spot size for energy from the source impinging on the skin to provide a desired amount of energy to a desired depth for treatment. In another embodiment the apparatus includes an interlock to prevent the laser from producing light unless the source is positioned to irradiate only the skin.
US08246606B2 Systems and methods for controlling inflammatory response
A method and system for controlling inflammatory response at an internal tissue site of a patient utilizes a reduced-pressure treatment device. Controlling the inflammatory response may be accomplished in a number of ways that involve treating the inflammatory milieu. Treating the inflammatory milieu may include removing or moderating pro-inflammatory stimuli, e.g., fluids, enhancing perfusion of the tissue at or near the internal tissue site, or providing reduced-pressure therapy. The reduced-pressure treatment device is placed at or near the internal tissue site and is fluidly coupled to an external reduced-pressure source. The reduced-pressure treatment device provides reduced pressure proximate the tissue site and treats the inflammatory milieu. The reduced-pressure treatment device for controlling inflammatory response may be a minimally-invasive treatment device.
US08246600B2 Multiple catheter assembly
A multiple catheter assembly (100) including a first catheter (110) having a first proximal end region (112), a first distal end region (114) terminating in a first distal tip (116), and an outer surface (120) defining at least a first lumen (122) extending longitudinally therethrough between a first distal and a first proximal opening. The assembly (100) also includes a second catheter (130) having a second proximal end region (132), a second distal end region (134) terminating in a second distal tip (136), and a second outer surface (140) defining at least a second lumen (142) extending longitudinally therethrough between a second distal and a second proximal opening. The first (122) and second (142) lumens are independent from each other for facilitating simultaneous flow in opposite directions. The outer surfaces (120,140) of the first and second catheters are releasably joined for allowing the first and second distal tips (116,136) and first and second proximal end regions (112,132) to be at least partially longitudinally split from each other. A method of inserting the catheter assembly (100) is also provided.
US08246590B2 Closed incision negative pressure wound therapy device and methods of use
A surgical tissue therapy device includes a sealant layer and a collection chamber. The sealant layer functions so as to create a sealed enclosure or space between it and the surface of a patient by forming, preferably, an airtight seal around a surgical area of skin trauma. The closed incision tissue therapy device also comprises a collection chamber, which may comprise an elongate tubular chamber with a plurality of longitudinally spaced openings. The collection chamber may be configured to be in fluid communication with the sealant layer and the area of skin trauma and functions as to distribute the negative pressure applied to a surgically closed area of skin trauma. Preferably, the pressure under the sealant layer is reduced by expanding the volume of the enclosure space and thereby decreasing the density of air molecules under the sealant layer. The collection material may comprise a material and/or a configuration that permits length changes based upon the length of the corresponding surgical wound or incision.
US08246587B2 Infiltration cannula
An infiltration cannula and method of using the infiltration cannula during an infiltration procedure are disclosed herein. The infiltration cannula includes: a tubular needle and a hub. The tubular needle has a proximal end and a distal end. The tubular needle also has a plurality of apertures disposed in a pattern about the distal end. The apertures are configured to infiltrate fluid into the subcutaneous tissue of a patient. The hub is configured to be held by a person performing the infiltration procedure. The hub has a first end and an opposing second end. The first end is attached to the proximal end of the tubular needle and the second end includes a connector configured to connect to an input source for receiving the fluid to be infiltrated into the subcutaneous tissue of the patient. The fluid flows from the connector, through the hub and into the tubular needle.
US08246585B2 Hemostatic clip
A device for inhibiting blood leakage from the proximal end of a catheter. The device includes a resilient body having a proximal portion and a distal extension portion extending away from the proximal portion and terminating at a first end. The proximal portion and the distal extension portion share a common axis and together define a generally cylindrical passage at least partially therethrough. The distal extension portion is shaped to interface with the catheter and in a substantially sealing relationship. The cylindrical passage is sized to receive a surgical guidewire therein in close apposition.
US08246582B2 Microneedle transdermal transport device
A transdermal transport device includes a reservoir for holding a formulation of an active principle, and a needle with a bore extending along the length of the needle from a first end of the needle to a second end of the needle. The second end is substantially aligned to a plane parallel to a body surface of a biological body when the device is placed on the body surface. The device also includes an actuator which pumps the formulation through the bore of the needle between a target area of the body and the reservoir.
US08246580B2 Aspiration control via flow or impedance
A microsurgical system capable of controlling aspiration and detecting an occlusion via monitoring a change in either suction flow rate or suction impedance.
US08246579B2 Surgical system having means for pressurizing venting valve
The present invention provides a surgical system 10 for aspiration of a biological material comprising a source of irrigation fluid 24, a collection cassette 30, a pump 40 for creating a vacuum in the collection cassette 30, a handpiece 50 applied to a surgical area for infusing irrigation fluid and for aspirating a biological material, conduits 60 and 62 connecting the handpiece to each of the source of irrigation fluid and the collection cassette and means 70 for isolating the pump from the handpiece to prevent creation of vacuum within the conduit 62 and the collection cassette 30 after receiving a stop signal.
US08246578B2 Puncture device
A puncture device includes a first base plate; a second base plate; a base plate connection part having flexibility and connecting the first base plate and the second base plate in a horizontal direction; an adhesive means provided to surfaces in a same direction of the first base plate and the second base plate; and a puncture needle moving means provided in the first base plate and movably supporting a puncture needle. The puncture needle is supported away from a surface of the adhesive means a given distance and movable substantially in parallel to the surface of the adhesive means.
US08246576B2 Method and apparatus for delivery of a therapeutic agent with an expandable medical device
Described herein is a medical device that has a collapsed configuration and an expanded configuration wherein one or more polymeric network layers are applied to the substrate and microparticles embedded in the polymeric network. The polymeric network layer or layers is/are configured to retain the microparticles when the device is in a collapsed configuration and to release the microparticles when the device is in an expanded configuration. Methods for delivering a therapeutic agent using the device and making the device are also disclosed.
US08246574B2 Support catheter
A support catheter that can be used to aid positioning of a guidewire and other medical devices. The support catheter includes a catheter body having a length, and a supporting structure formed or disposed in or on the catheter body. The catheter support structure, whether alone or in combination with the other portions of the support catheter, provides flexibility, stiffness, and torqueability to the support catheter.
US08246573B2 Detecting empty medical pump reservoir
A medical device system comprises a reservoir configured to store a therapeutic fluid and a medical pump configured to deliver the therapeutic fluid from the reservoir to a patient. The system also comprises a sensor that can detect a characteristic associated with the pump and a processor to determine if the characteristic detected indicates the reservoir is empty or near empty. The characteristic may comprise a property associated with the energization of an actuation mechanism configured to be energized to provide a pump stroke. The characteristic may also comprise a characteristic of a noise made by an actuator within the pump at the end of a pump stroke.
US08246567B2 Method of monitoring hypertensive haemodialysis patients
The invention relates to a calculation and control system for determining whether a patient intended to follow several sessions of hemodialysis treatment falls or not within one group among several groups of hypertension-affected patients, the system comprising: a) means for determining the value of at least one parameter representing the mass interdialytic evolution of the patient, for at least two sessions, b) means for determining the value of at least one parameter representing the plasmatic conductivity of the patient for at least two sessions, c) means for determining the value of a parameter representing the ionic mass transfer of the treatment for at least two sessions, d) programmed means for determining whether the patient falls or not within a group of hypertension-affected patients as a function of the interdialytic mass evolution of the patient, and/or of the plasmatic conductivity and/or of the ionic mass transfer.
US08246563B2 Cardiac rhythm management device and sensor-suite for the optimal control of ultrafiltration and renal replacement therapies
A cardiorenal patient monitoring system comprising, either implanted or non-implanted device(s), remote peripheral device(s), computer network(s), host, and communication means between the device(s), computer network(s), and host. The preferred embodiment shows an advanced patient monitoring system for using an implanted cardiac device and a dialysis machine in renal therapy. In addition, the method of advanced patient monitoring is in conjunction with the advanced patient monitoring system is disclosed.
US08246561B1 Systems, devices and methods for treating acute dorsal fracture dislocations of the PIP joint
Systems, device and methods are described for maintaining concentric reduction of the proximal interphalangeal (PIP) joint of a finger with few as two orthopedic pins, one inserted through the head of the proximal phalanx concentric with the axis of rotation of the joint (i.e., a transverse pin), and the other through the middle phalanx at a location between the PIP and distal interphalangeal (DIP) joint (a dorsal pin), and applying a force between the two pins. A surgical kit is described which may include such components as a dorsal pin, a transverse pin, a pin placement guide for use in reducing the joint fracture dislocation and then drilling holes for the pins or for inserting self-drilling pins, and a fixation device for coupling and applying a force between the dorsal and transverse pins. The components of the surgical kit are described, including various configurations of the fixation device.
US08246559B2 Two degree of freedom powered orthosis
Weakened and restricted limb movement is aided by powered orthosis having one or more independent dimensions of controlled movement and a control system.
US08246558B2 Quick connect apparatus and method
A device and method for releasably connecting together two elements, such as two orthotic devices, or two elements of an orthotic device is provided. A quick connect apparatus and method of use is disclosed that quickly and easily enables a user to attach and detach two devices or two elements of a device, such as the elements of an orthosis or a prosthetic. An example device that may easily be converted back and forth between an ankle-foot orthosis and a knee-ankle-foot orthosis is disclosed, along with steps for making and using same.
US08246556B2 Foot compression system
Methods and systems for dynamic compression of venous tissue enable improved blood movement in the extremities. In accordance with an exemplary embodiment, a pressure pad provides a compressive force to the venous plexus region of the foot. The pressure pad is successively withdrawn and re-pressed against the foot. Improved blood circulation may reduce the occurrence of undesirable complications such as deep vein thrombosis, ulcers, and the like.
US08246549B2 Method for predicting stroke and pain in a human patient
A method for predicting the onset of any (NO)-related negative influence of hemolysis, such as pain or the likely occurrence of a stroke, in a human patient by detecting abnormal levels of hemolysis, through the measurement of one or more breath gas concentrations.
US08246547B2 Packages of apparatus for non-invasive detection of pulse rate and blood flow anomalies
The present invention provides a package for an apparatus for non-invasively monitoring of blood flow of an object, a magnetic field sensing device, and a magnetic source positioning device.
US08246546B2 Method, arrangement and apparatus for monitoring fluid balance status of a subject
A method and apparatus for monitoring fluid balance status of a subject are disclosed. A hemoglobin measure indicative of hemoglobin concentration in the blood of a subject and at least one physiological parameter responsive to blood volume changes in the subject are determined and concurrent behavior of the hemoglobin measure and the at least one physiological parameter is indicated to a user, thereby to give an indication of fluid balance status of the subject. The cause and/or reliability of the fluid balance status may also be indicated.
US08246542B2 Method and device of diagnosing bone strength
A bone strength diagnostic device includes a wave-transmission module that transmits an ultrasonic wave obliquely to a bone covered with soft tissues; a wave-reception module that receives the ultrasonic wave that exits from the bone to the side of the soft tissues; a shape detection module for detecting the shape of the front surface of the bone; and a speed-of-sound deriving module for deriving the speed of sound of the ultrasonic wave that propagates along the front surface of the bone, based on the received wave signals, and the shape of the front surface of the bone detected using the shape detection module.
US08246541B2 Real-time microdialysis system
Microdialysis systems and methods that enable self-diagnostic functions for microdialysis, including continuous monitoring of diffusion, convection, and osmosis, as well as providing intelligent flow rate control, to mitigate variability in analyte recovery. The microdialysis system measures real-time tracer concentration levels in the dialysate and/or real time flow rates of the dialysate. A control circuit may compute the real-time tracer concentration levels in the dialysate and/or real-time flow rates of the dialysate based on real time tracer concentration data from an in-line tracer concentration meter and real-time flow rate data from an in-line flow rate meter. Analyte concentration data for the dialysate may also be measured using an analyte concentration meter. The control circuit may compute a corrected analyte concentration for the dialysate based on the analyte concentration data, the tracer concentration data, and the flow rate data in various embodiments.
US08246536B2 Treatment tool insertion channel of endoscope
A treatment tool insertion channel of an endoscope, which is arranged through an inside of an insertion part that includes a flexible tube and a bendable part, includes a flexible inner tube, a spiral groove formed around the flexible inner tube over an entire length of the bendable part and the flexible tube, at least one coil wound along a bottom of the spiral groove, and at least one type of filler with which the spiral groove is filled. The treatment tool insertion channel includes a first portion that includes a part inside the bendable part and a second portion at a proximal end side of the first portion, the first portion being configured more flexible than the second portion.
US08246531B2 Incubator for non-ionising radiation imaging
An incubator for imaging with non-ionising radiation adapted for the care of newborn babies, which integrates a system projective or tomographic imaging system, or both simultaneously, which makes use of non-ionising radiation in the band of the electromagnetic spectrum included between ultraviolet light and far infrared, a system which can be used to view a subject (11) located in the incubator (19) such that this projective or tomographic image can be morphological or functional.
US08246528B2 Implant for treating the internal walls of a resection cavity
The invention relates to an implant for treating a cavity that is created as a result of a resection, the implant being modular and the modules being interconnectable.
US08246527B2 Systems and methods for folding
A folding system for folding leading and/or trailing flaps of container blanks is provided. The system may include a conveyor having a conveying surface configured for conveying the blank along a predetermined path to a first folding position and a second folding position, a folding apparatus, and a control system. The folding apparatus may include a drive assembly and a folding tool. The control system may be operatively coupled to the folding apparatus and operable to control movement of the folding tool between a first rotational position and a second rotational position. Rotation of the folding tool to the first rotational position may cause the leading flap of the container blank positioned in the first folding position to fold about a leading flap fold line. Rotation of the folding tool from the first rotational position to the second rotational position may cause the trailing flap of the container blank positioned in the second folding position to fold about a trailing flap fold line.
US08246526B2 Covering layer for electrophotographic printing rollers
The invention relates to a novel covering layer for electrophotographic printing rollers with improved scratch resistance. Said covering layer consists of between 50 and 75 wt. % of cycloaliphatic epoxides, between 20 and 60 wt. % of aminofunctional silica nanoparticles, and between 0 and 2 wt. % of perfluoroalkyltrialkoxysilanes. The aminofunctional nanoparticles are produced from aminoalkyltrialkoxysilanes preferably by means of sol/gel technology.
US08246522B2 Stair climbing exercise apparatus with improved bellows
An exercise apparatus includes a housing, a pair of pivoting foot treadles and a pair of reciprocating bellows that support the foot treadles. A sealed air system including a conduit interconnects the bellows and is operable for reciprocating transfer of air from bellow to bellow. Each of the foot treadles is pivotably movable between upper and lower positions, and has a resting position between the upper and lower positions. The resting position of the foot treadles defines a resting position of the bellows while the upper and lower positions of the foot treadles respectively define elongated and compressed positions of the bellows. In use, the elongated and compressed positions of the bellows are each no more than 5 degrees off the center resting position thereby reducing stress on the bellows.
US08246519B2 Automatic clutch control apparatus
In an automatic clutch control with respect to a pressure-disengaged type of automatic clutch, when an working oil temperature increase has occurred in a state in which a clutch master cylinder is not in communication with a reservoir tank, a clutch stroke position is changed in a clutch engaging direction such that the number of engine revolutions matches the number of engine revolutions at the point in time when the clutch master cylinder and the reservoir tank became not in communication.
US08246518B2 Shifting system for a vehicle transmission
The invention is a transmission shifting system for a vehicle, the vehicle having a transmission having a push-pull and rotating member for operating the transmission movable in an H pattern. In detail, the invention includes a first reversible electric motor coupled to the member for moving the member backwards and forwards. A second reversible electric motor is coupled to the member for rotating the member clockwise and counter-clockwise. The second motor coupled to the member by means of a biasing assembly such that a biasing force can be applied to the member when the second motor rotates without the member rotating. A transmission shifter control system is provided for sequencing the operation of the first and second motors so to move the member in the H pattern upon receipt of an actuation signal.
US08246514B2 Transmission device, power output device, and control method of power output device
A transmission device that is built into a power output device outputting power to a drive shaft in combination with a power source and that includes an automatic transmission that changes a shift speed by switching an engagement state of at least one friction engagement element and transmits power from the power source to the drive shaft, the transmission device includes an engagement pressure regulating device and a control unit.
US08246512B2 Control device for vehicular power transmitting device
In a control device for a vehicular power transmitting device, if engine torque TE generated with using a fuel other than a basic fuel by an internal combustion engine (8) connected to a shifting mechanism (10) for power transmitting capability, exceeds torque TES generated with using a basic fuel, a downshift is initiated at a lower accel-opening than that at which the downshift is initiated with using the basic fuel. That is, the shifting is performed at a shift point enabling the suppression of a torque increase in consideration of an increase in engine torque TE generated by the internal combustion engine, thereby preventing rotary elements of the shifting mechanism (10) from reaching high-speed rotations during a transition in downshift. This minimizes a drop in durability of the shifting mechanism (10).
US08246507B2 Control apparatus for vehicle drive system
A control apparatus for a vehicular drive system, including an engine speed limiting device configured to limit operating speed of engine to an upper limit determined according to speed ratio of automatic transmission portion, so as to prevent a rise of operating speed of first electric motor into excessive rise range, so that the excessive rise of the first electric motor speed due to a shifting action of the automatic transmission portion is prevented to improve the durability of the first electric motor. For example, the speed of the engine is limited to the upper limit when the automatic transmission portion is shifted to a failure gear position established as a result of a failure of the automatic transmission portion to perform a shifting action following a shifting boundary line map, so that the vehicle can be driven upon the failure of the automatic transmission portion, while preventing an excessive rise of the first electric motor speed.
US08246506B2 Control apparatus for vehicular power transmitting system
A control apparatus for a vehicular power transmitting system including (a) an electrically controlled differential portion which has a differential mechanism and a first electric motor connected to a rotary element of the differential mechanism and which is operable to control a differential state between rotating speeds of its input and output shafts by controlling an operating state of the first electric motor, and (b) a step-variable transmission portion which constitutes a part of a power transmitting path between the electrically controlled differential portion and a drive wheel of a vehicle, the control apparatus including a coasting-shift-down control portion configured to implement a coasting shift-down action of the step-variable transmission portion during a coasting run of the vehicle, only when a parameter correlating with a shaft torque of the step-variable transmission portion during the coasting run is held within a predetermined range.
US08246504B2 Multi step transmission
The multi step transmission comprising gear sets (P1, P2, P3, P4), eight shafts and six shift elements. The sun gear of set (P1) couples the drive shaft, the carrier of set (P1) couples shaft (3) which couples a housing via brake (03), the drive shaft via clutch (13) and shaft (5) via clutch (35). Shaft (5) couples the ring gear of set (P2), to the sun gears of sets (P3, P4), and the drive shaft couples, via clutch (18), shaft (8) that couples the carrier of set (P4). Shaft (6) couples the ring gear of set (P1) and, via clutch (67), shaft (7) that couples the carrier of set (P2). The sun gear of set (P2) couples the housing. The ring gear of set (P3) couples shaft (4) that couples the housing via brake (04). The output shaft couples the ring gear and carrier of sets (P4, P3) respectively.
US08246503B2 Epicyclic gear system with improved lubrication system
A journal bearing that includes a central body having first and second passageways and a filter. The central body extends axially and is adapted to be supported at each outer end. The first passageway extends generally axially through a portion of the central body. The filter is disposed in the first passageway and is configured to trap debris from a lubricant fluid flowing therethrough. The second passageway extends between both the first passageway and an exterior surface of the central body to allow for delivery of lubricant fluid thereto.
US08246499B2 Drive apparatus
A hybrid drive unit that includes an input shaft connected to an engine; an output shaft connected to wheels; a first rotary electric machine; a second rotary electric machine connected to the output shaft; a power distribution device that distributes a rotational driving force of the input shaft to the output shaft and to the first rotary electric machine; a second rotary electric machine fixing device that selectively fixes a rotor of the second rotary electric machine; and a transmission cutoff device capable of cutting off transmission of rotation between the output shaft and the second rotary electric machine at least in a state when the rotor of the second rotary electric machine is fixed.
US08246498B2 Chain transmission device
In a chain transmission, the link plates of a roller chain or rollerless bushing chain are formed with pairs of teeth. A sprocket has a central set of sprocket teeth for meshing with the rollers or bushings, and sets of side sprocket teeth for meshing with the teeth of the link plates. The teeth of the link plates function as a silent chain. After an inner flank of a link plate tooth comes into contact with a side sprocket tooth, a roller and an outer flank of the link plate tooth are seated on the sprocket.
US08246494B2 Soccer training apparatus and method
A soccer training apparatus comprises a net capable of being placed in a deployed position, connected to or located adjacent a soccer goal frame and above a soccer playing surface, so as to cover a portion of a target opening bounded by the soccer goal frame and soccer playing surface. The net includes a peripheral edge located relative to the soccer goal frame so as to form a gap which extends around the net in the deployed position which permits a soccer ball to pass through and enter the soccer goal area.
US08246492B2 Baseball/softball batting tee
A baseball/softball batting tee has a base, and one or more support post and ball holding assemblies mounted in a substantially vertical orientation on the base. A primary support post and ball holding assembly has an adjustable height provided by an upper tube that is telescopically received within a lower tube and a ball supporting rod similarly telescopically received within the upper tube. Wiper seals and bushings are mounted in the upper ends of both tubes for sealing engagement with the respective telescopically received components, providing a friction fit sufficient to “lock” the relative positions of the tubes and rod to set the tee at a desired height while still allowing the tubes and the rod to be easily telescoped together. A secondary support post and ball holding assembly is also provided that can be readily interchanged with the primary.
US08246488B2 Hybrid golf club head
A hybrid type golf club head is disclosed herein. The hybrid golf club head preferably has an exterior heel weight, an exterior toe weight, and interior sole weight and a stainless steel body. The hybrid golf club head preferably has a moment of inertia Ixx about a center of gravity ranging from 2100 to 2300 grams-centimeters squared.
US08246485B2 Golf club shaft
A golf club shaft has a more attractive appearance than a coating of plating and also achieves a rustproofing effect within the shaft, while avoiding the problem of an increase in weight and processing of effluents associated with plated shafts. The golf club shaft has a shaft body, a covering film formed by chemical treatment of an outside surface and an inside surface of the shaft body, a coating film layer formed by electric painting on the covering film of at least the outside surface; and a pigment layer, in which a polarizing powder is dispersed, which is coated on the coating film layer.
US08246483B2 Single-arm golf club
A golf club includes a shaft with a length, a distal end, and a proximal end separated from the distal end by the length. A hand grip is disposed along the length and an arm-securing attachment is coupled to the proximal end of the shaft and has a substantially spiral-shape with a spiral direction away from the proximal end of the shaft. A club face is coupled to the distal end of the shaft.
US08246481B2 Putters with enhanced alignment visualization
Putters and putter heads better camouflage the main body of the head and/or highlight the alignment aid. The top surface of the head (when viewed from a ball address orientation) may be finished in a non-reflective, matte finish, optionally, in a dark color and/or in a color or colors selected so as to blend into or match the color of a golf green. At least some portion of the shaft member may be colored and finished in this same manner. These features help in visualization of the alignment aid (which also may be designed to help in alignment). If desired, the club head and/or shaft color and finish may be customized based on the greens at a specific golf course, greens in a specific geographical region, greens of a specific grass type, greens at a specific time of year or under specific conditions, etc.
US08246480B2 Golf ball holding structure
An apparatus which uses a club having a head portion and a shaft. Integrated with the head portion is a shaped recess with a golf ball holder. The golf ball holder is capable of gripping and holding a golf ball with a predetermined force requirement for release, which requires the user to execute a proper golf swing to release the ball. The predetermined force requirement may be adjustable. The user also may vary the angle of the club face on various planes relative to the shaft, thereby changing the swing required to release the ball.
US08246478B2 Engine shaft in the form of a fiber-composite plastic tube with metallic driving and driven protrusions
On a low-pressure turbine shaft made of fiber-composite material, the connection to the metallic driven protrusion or the driving protrusion (1), respectively, is made via an adapter (3) formed onto the latter, with pylons (6) extending beyond the circumferential area of the latter and on which the fibers (4) are deflected and guided in accordance with the fiber orientation in the fiber-composite material, enabling high torsional forces to be transmitted via the small connecting zone.
US08246475B2 Constant velocity joint
A boot assembly and constant velocity joint utilizing the boot assembly is provided. The constant velocity joint and boot assembly includes a first shaft, the first shaft having an axle portion extending between a first end and a second end, at least one of the first end and the second end having an enlarged joint portion. It also includes a hollow boot disposed on the first shaft having a joint end and a shaft end, the joint end disposed proximate the enlarged joint portion and the shaft end disposed proximate the axle portion. The constant velocity joint also includes a spacer, the spacer having an inner surface disposed on the axle portion and an outer surface having the shaft end of the boot disposed thereon.
US08246470B2 Mass storage repository for a wireless network
A video repository unit includes a plurality of disk drives arranged in a redundant array and circuitry to control writing/reading of video programs to/from the redundant array. A wireless transceiver receives video programs and transmits a selected video program to a remote viewer responsive to a request received by the wireless transceiver. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.
US08246465B2 Game system, server and terminal machine
A game system according to the present invention includes a server and a plurality of terminal machines; the server holds setting state information to be set in the terminal machines; the setting state information is provided to the terminal machine; and, when obtaining the setting state information, the terminal machines set the setting state information as its own local state, and executes a game based on the local state. The local states of the terminal machines vary with the situations of the game, and the local state at the moment of game end is transmitted to the server. The server which has received the local state at the moment of game end from the terminal machine updates the setting state information into the local state.
US08246463B2 Game system and game apparatus
According to a game system and a game apparatus of the present invention, when other game apparatus or a group to which a plurality of game apparatuses belong are present in a range where wireless communication by the game apparatus operated by a player is available, the other game apparatus and the makeup of the group are notified to the player. Thus, the player can form a group of desired game apparatuses by determining a group to enter in consideration of the displayed group information, and execute a multiplayer game using wireless communication.
US08246455B2 Video game with player directed discrete and free camera modes
A game machine includes a first virtual camera control unit which determines a change direction in which a posture of the virtual camera is changed, based on a state of operation of an operation unit, and changes a posture of the virtual camera such that the virtual camera is directed in a direction displaced from a current direction in the change direction by a predetermined angle; a second virtual camera control unit which determines a direction in the virtual three dimensional space based on the state of operation of the operation unit, and changes the posture of the virtual camera such that the virtual camera is directed in the determined direction; and a virtual camera control switching unit which switches between a state in which the first virtual camera control unit controls the virtual camera and a state in which the second virtual camera control unit controls the virtual camera.
US08246454B2 System for converting television commercials into interactive networked video games
Methods, systems, and computer programs for converting television commercials into interactive network video games are presented. In one method, a broadcast or streamed commercial is accompanied by an interactive segment. A media player coupled to the broadcast or streaming media source identifies the existence of the interactive segment and presents the user with an enhanced and interactive mini-game commercial that can be played with other “viewers” in a common or disperse demographic. Multiple methods for content delivery are provided, including a model where television commercial is inserted within consecutive frames of the television program, and a model where the commercial is overlaid on frames of the television program allowing the user to play the game while the television program is displayed. In a preferred embodiment, the termination of the interactive mini-game commercial is set within a fixed time period commensurate with traditional spot television advertising.
US08246453B2 Wagering game device having ubiquitous character set
A wagering game machine uses a single character set for displaying text in multiple languages. The character set may also be used for printing materials, such as ticket printing. In one embodiment, the character set comprises Unicode standard characters, where each character in the font is represented by a unique number, which maps to the Unicode standard, regardless of platform. This allows programs that conform to the Unicode standard to deal with text in multiple languages.
US08246452B2 Wagering game, gaming machine and networked gaming system and method with a multiple-progressive wheel game and associated methods
A method and gaming machine are disclosed for operating a game with a primary and embedded game. An embedded game is disclosed as a bonus game with one embodiment animating miniature reels inside the primary game symbol. Each embedded slot game may have its own progressive, or may be tied into the progress associated with the primary game. Each embedded slot game will have its own paytable, and may be a miniature version of a well-recognized full-sized slot game. Also disclosed are a wagering game, a gaming machine and a networked gaming system and associated methods including a multiple-progressive wheel game. A player may win all of a set of wheel-based progressive award during play of a single game.
US08246447B2 Gaming device holding reels with trigger symbols and providing free reel spins
A game variation played on a gaming device displaying reels is disclosed. The game grants awards to the player for certain combinations of symbols. When a player gets one or more special symbols in an initial game, the player gets a free spin of one or more reels while the reels that display the special symbols are held. The player continues to get free spins as long as additional special symbols are displayed after each spin. The player may be granted awards for winning symbols combinations after each spin. In one embodiment, a certain number of special symbols across a payline awards the player a jackpot. In another embodiment, the game is a bonus game where any reels containing special, or trigger, symbols are shifted by one position after each free spin and then held for the next free spin. Only reels that do not display a trigger symbol are spun. The bonus game ends when there are no more trigger symbols displayed. The game may be played on a video gaming machine or a motor-driven reel machine. Various embodiments are described herein.
US08246444B2 Gaming device having a re-triggering symbol bonus scheme
A gaming device having a bonus scheme wherein a combination of bonus symbols trigger a bonus game and any one of the bonus symbols in the bonus game provides a player with an award. The award may be an extension of the bonus game by providing the player with additional spins or games. Also, the award may modify the combination and type of bonus symbols needed to enter the bonus game. Furthermore, the award may modify the award values in the bonus game. Therefore, a combination of bonus symbols triggers the bonus game and also triggers the gaming device to provide bonus awards in the bonus game. The re-triggering symbol award bonus scheme changes the probability of winning for the player and therefore creates a higher level of excitement and enjoyment of the game.
US08246436B2 Bonus games coordinated over network
A bonusing game and method usable with games of chance in which all participating machines are synchronized so their independent bonus rounds play simultaneously. In one embodiment, one player terminal triggers a bonus round and is deemed a “seller” in a simulated auction, and all other active player terminals in a bank also participate as simulated “buyers.” The “seller” makes choices of items to sell which are communicated to the “buyers.” The “seller” watches as simulated bids are placed on their items, and “buyers” participate in simulated bidding of items shown on their screens. The seller and all buyers are awarded some winnings, enabling all players' terminals that run the simultaneous simulated auction bonus round to win each time the simulated auction bonus game is invoked.
US08246433B2 Team based fantasy sport contest
A method provides a fantasy sport contest having rules wherein a plurality of participants are permitted to populate respective fantasy rosters with actual athletes for purposes of competing with each other based on corresponding real-life field-of-play performances of the actual athletes. The method includes restricting a population of each of a first and second fantasy roster for respective first and second participants to actual athletes who are teammates on respective first and second real-life team, and measuring corresponding real-life field of play performance of the actual athletes on the first and second fantasy rosters. A ranking is established as between the first participant and the second participant based on the respective performance measurements, and is further displayed. The first real-life team and the second real-life team may be the same real-life team, or different real-life teams.
US08246432B2 Electronic gaming based on intermediate points in an event
Systems and methods related to gaming based on the results at intervals of a race. Other embodiments are disclosed.
US08246431B2 Bet matrix for entering bets regarding intermediate points in a race event
A method of providing and managing bets is provided. One or more particular race participants in a race event are determined. For each intermediate point within a race event, one or more particular possible positions of race participants at that intermediate point are determined. A bet comprising a plurality of bet components is generated, one or more of the bet components being defined by the particular race participants and the particular possible positions of race participants determined for at least one of the intermediate points. Intermediate race results are received for each intermediate point identifying the actual positions of the particular race participants at that intermediate point. A result of at least one bet component is determined based at least in part on the particular race participants, the particular possible positions of race participants determined for at least one intermediate point, and the received intermediate race results for at least one intermediate point.
US08246430B1 Chimney cap
A chimney cap capable of being secured to a chimney and including a base; an annular collar member for insertion into a chimney, and having an outside circumference smaller than an opening of the chimney so as to be readily received therein; an annular shaped mesh member that is supported about the collar; a top supported over the base; and a plurality of support rods attached to the collar and for the purpose of supporting the annular shaped mesh member. The annular shaped mesh member has discharge openings for air flow and at least one elongated slot through which one of the support rods extends for securing the annular shaped mesh member. The elongated slot in combination with the one support rod enables adjustment of the diameter of the annular shaped mesh member.
US08246421B2 Arc surface grinding device
A grinding device includes a fixed barrel, a moving barrel, a grinding plate, and an actuator. The fixed barrel defines a chamber and includes a number of inner surfaces substantially parallel to a central axis, each of which defines a holding groove therein for holding a workpiece. The moving barrel is received in the chamber and includes a side surface substantially parallel to the central axis and defines an installation groove. The grinding plate is fixedly installed in the installation groove. The actuator is configured for driving the moving barrel to spin and move back and forth along the central axis, and driving the moving barrel to move towards a workpiece so that a surface of the workpiece is grinded into a desired arc surface by the grinding plate, and driving the moving barrel to move towards another workpiece after the desired arc surface of the workpiece is obtained.
US08246413B2 Method for making field emission device
A method for making a field emission device includes the following steps. An insulative substrate is provided. An electron pulling electrode is formed on the insulative substrate. A secondary electron emission layer is formed on the electron pulling electrode. A first dielectric layer is fabricated. The first dielectric layer has a second opening to expose the secondary electron emission layer. A cathode plate having an electron output portion is provided. An electron emission layer is formed on part surface of the cathode plate. The cathode plate is placed on the first dielectric layer. The electron output portion and the second opening have at least one part overlapped, and at least one part of the electron emission layer is oriented to the secondary electron emission layer via the second opening.
US08246406B2 Fin retention system for a water craft
A fin box for a water craft including: a fin box body having an elongated slot open at a first surface of the fix box and extending to a closed base of the fin box; a peripheral flange extending outwardly from the slot and defining an area of the first surface around the slot; the peripheral flange having a second lower surface and a third upper surface both offset vertically from the first surface and extending laterally from the fin box body, the second lower surface and said third upper surface further comprising a left and right side, each said left and right side surfaces extending transversely from the body portion to peripheral extremities of said peripheral flange, wherein at least one surface of said peripheral flange forms a transverse angle of taper with an axial median vertical plane of the fin box body.
US08246401B2 Kort nozzle
In order to indicate a Kort nozzle configured rotatable around the rudder axis of a ship, for which the occurrence of recirculations or of swirls is avoided or reduced even with an angular position with respect to a longitudinal axis of the ship and a globally uniform flow pattern adjusts as far as possible, at least one opening is provided in each of two central areas of a nozzle ring enveloping a ship's propeller.
US08246394B2 Terminal connector with a crimping portion with recesses
A plurality of recesses are formed on a surface of a wire barrel where an electric wire is provided. In a state before the electric wire is crimped onto the wire, barrel, at least one of sides comprising rims of an opening of each recess of a quadrangular shape is a crossing side crossing at an angle of from 85 degrees to 95 degrees to an extending direction. In a state before the electric wire is crimped onto the wire barrel 16, the crossing sides of a plurality of recesses positioned adjacent to each other in the extending direction are so arranged as to overlap with each other in the extending direction.
US08246392B2 Securable connector
An electrical cable connector comprising an electrically conductive central body, an outer sleeve rotatably coupled to the central body, and a tubular cam member disposed between the outer sleeve and the central body. When the outer sleeve is rotated around the central body from a first rotational position to a second rotational position, the tubular cam member is displaced from a first axial position to a second axial position, thereby causing a radial camming region in an axial through bore of the tubular cam member to displace fingers of the electrically conductive central body radially inwardly. In that manner, when the connector is plugged into a port or jack comprising a cylindrical body that is at least partially enclosed by the fingers of the central body of the connector, the fingers clamp onto the body of the port, thereby securing the connector to the port.
US08246391B1 Connector terminal
A connector terminal is assembled in an insulating housing defining a receiving cavity of which front and rear sides protrude face-to-face to form two blocking eaves. The connector terminal has a fastening strip of which a bottom edge protrudes downward to form two elastic arms spaced from each other, and a soldering portion between the two elastic arms. The elastic arms are apart from two opposite side edges of the soldering portion to define two receiving intervals between the soldering portion and the elastic arms. Distal ends of the elastic arms oppositely protrude to form two fastening barbs. The soldering portion and the elastic arms are inserted in the receiving cavity. The fastening barbs slide through the blocking eaves to be hooked under the blocking eaves respectively and the fastening barbs can be avoided scraping the connector by means of cushion effects of the receiving intervals.
US08246390B2 Integral bonding attachment
An integral bonding attachment includes an insulated section of a conductive wire with an exposed, uninsulated section. A sleeve covers the insulated and uninsulated sections of the conductive wire, and the sleeve includes a flattened section encasing at least a portion of the uninsulated wire section to form a generally integral structure with the core of the conductive wire. At least one generally tubular section is positioned at an end of the flattened section to engage the insulated section of the conductive wire. An aperture may pass simultaneously through the inner core and flattened sleeve section for attaching the integral bonding attachment to a structure.
US08246387B2 Connector constructions for electronic applications
An electronic wiping torsional connector for use in connecting to mating contacts on an insulating base. The connector includes a plurality of contacts 1-10, each having a contact area 93 adapted for wiping contact to a pad, an anchor area 92, and flattened, ribbon-like connector for receiving a wiping contact. Contacts 1-10 twist against an anchor 92 when the insulating base is inserted into the connector to provide the wiping contact.
US08246386B1 Adapted modular connector
An electrical connector for connecting a circuit board to a plug of an electric cable that has at least one electrical conductor includes a rigid housing that has at least a front end, a lower end adapted for mounting to the circuit board, and a rear end. A rigid insert is adapted to fit within the housing and includes an open front end adapted to receive the plug of the electric cable. A plurality of lower rear conductors and optionally upper rear conductors project away from the rear end of the insert. A plurality of insert conductors are adapted to convey electrical signals between the conductors of the plug and the plurality of rear conductors. A modifier circuit board is adapted for attachment to the insert and for modifying electrical signals between the rear conductors of the insert through a modifier circuit.
US08246382B1 Bendable patch panel structure
A bendable patch panel structure installed on a chassis includes a patch panel and a fixing element. The patch panel includes a first panel, a second panel, a hinge pivotally coupled between ends of the first and second panels, and a connecting plate separately installed at other ends of the first panel and second panel and pivotally coupled to the chassis. After the first and second panels are bent and adjusted, a fixing element for the appropriate connection is selected according to the shape of the two unfolded metal plates of the hinge, such that the installer can adjust the bending condition of the patch panel in a time-saving, effort-saving, quick and easy manner.
US08246381B1 Adapter
A disk drive adapter which includes an enclosure, a circuit board, and two mounting pieces extending forwards. A first connector provides connections which match the I/O connections of the disk drive, as the disk drive is securely latched and held between the mounting pieces.
US08246380B2 Connecting device
A connecting device includes a cable transmitting a signal, a carrier receiving the cable, a sliding member slidable on the carrier, and a resilient component. The carrier includes a first side plate and a second side plate opposite to the first side plate, and a fixing post is secured in the carrier adjacent to the first side plate. The resilient component is secured to the fixing post and the sliding member, and the cable runs between the fixing post and the sliding member, wherein the resilient component is elastically deformable between a first state and a second state. In the first state, the resilient component is in an original state, substantially all of the cable is in the carrier, and the sliding member abuts the second side plate. In the second state, the resilient component is in elastically deformed, substantially all of the cable is exposed from the carrier, and the sliding member slides adjacent to the first side plate.
US08246379B1 Battery connector
A battery connector includes an insulating body having a base board and a fastening tongue protruding upward and then extending forward from a rear of the base board, and an electrical terminal which has a base plate, two elastic arms parallel and apart located over the base plate by means of two rear ends thereof curvedly connected with a rear edge of the base plate respectively, and two contact arms oppositely extending outward from two front ends of the elastic arms. The base plate is inserted rearward to be clipped between the fastening tongue and the base board, and the elastic arms are located at two opposite sides of the fastening tongue. The contact arms can be respectively connected with the positive electrode of one of two batteries and the negative electrode of the other battery to realize a series connection between the two batteries.
US08246378B1 Tap connector having pivotally connected first and second clamping plates with blades to pierce first and second wires
A tap connector includes a first clamping plate and a second clamping plate pivotably connected to the first clamping plate. The first clamping plate and the second clamping plate each define a channel. A conductive blade extends from a sidewall of one channel. The channels of the first clamping plate and the second clamping plate corporately form a receiving space to accommodate a wire, after the second clamping plate is pivoted to the first clamping plate. The conductive blade pierces the wire to be electrically connected to the wire.
US08246377B2 Connector housing with integrated cable clamp
In a connector housing with integrated cable clamp, it is proposed to provide a receptacle sleeve for an electrical cable that is integrally formed on the connector housing and provided with clamping elements that are distributed over the radius and point in the mating direction. When a pressure screw is screwed onto the receptacle sleeve, the clamping elements are pressed radially inward and the electrical cable is clamped in position.
US08246375B2 Circuit board clamp means
An electrical connector for connecting the bare end of a horizontal conductor with a horizontal printed circuit board, including a sectional housing having a base member seated on the printed circuit board. The base member contains an open-topped chamber and includes a vertical front wall the upper edge of which contains a vertical slot communicating with the chamber. A cover member is normally seated on the base member to close the chamber and the upper end of the slot. A lower electrically conductive cage member is arranged in the bottom of the chamber for electrical connection with the printed circuit board. The cover member is removable from the base member to open the tops of the chamber and the slot, thereby to permit the horizontal conductor bare end to be displaced laterally vertically downwardly into the slot and housing chamber toward electrical engagement with the lower cage member.
US08246372B1 Electrical connector with anchor mount
An anchored 522 male electrical connector is provided. A stationary housing 520 is combined with a coupling ring 540 to form an outer housing. An internal plunger 560 is housed in and spans the length of the outer housing. The stationary housing 520 mounts onto an anchoring surface via an anchor mount 522, while the coupling ring 540 is free to rotate about the internal plunger 560. The coupling ring is rotated via a hand grasp 441. The coupling ring rotation 442, 443 translates into forward and aft movement of the pin assembly 515. The connector provides forward 520-1 and backward stops 520-4 for limiting pin insertion and extraction moves to desired distances. Rotation via triple start threads 548, 525 readily overcomes insertion and extraction resistance of a bulky multi-pin assembly 515 and provides a smooth and controlled electrical connection. The connector may be sized to meet multi-pin connector needs or military standards.
US08246367B2 Electronic device connecting structure and function expansion device
A connecting structure reduces noise effects on an electronic device when hot docking the electronic device to mitigate against malfunctions. When a first electronic device having a first EMI shield is docked with a second electronic device having a second EMI shield, an ESD contact portion, which is connected to the second EMI shield and has higher in impedance than an EMI connecting portion, comes in contact with the first EMI shield earlier than the EMI connecting portion. Electrostatic charge carried on the first EMI shield moves slowly to the second EMI shield due to the high impedance of the ESD contact portion.
US08246366B2 Electrical card connector with a stop member for temporarily preventing a card from ejecting from the card release position
An electrical card connector includes an insulative housing, a number of contacts and a push-push mechanism. The push-push mechanism includes a slider, an elastic member for driving the slider and a locking arm fixed to the slider. The locking arm includes a hook protruding into a card receiving space for locking with the card when the card is fully inserted into the card receiving space at a card locking position. When the card is ejected under a normal speed, the locking arm can be outwardly deformed to disengage from the card at a card release position. When the card is ejected under an abnormal speed faster than the normal speed, the slider gets over the card release position where the locking arm is restricted by a stop member to prevent the hook from releasing the card.
US08246362B2 Computer peripheral device with a pin exerting a force to extend or retract a connector
A computer peripheral device is provided having a rotatable outer cover which is coupled to and selectively extends or retracts a connector of a printed circuit from a casing in which the printed circuit board is positioned when the outer cover is rotated. In one aspect, the cover includes a pin which extends through a groove formed in a seat coupled to an end of the circuit board. When the cover is rotated, the pin is urged against the groove to selectively extend or retract the connector from the casing. In another aspect, the cover includes a pin which extends into a groove formed in the printed circuit board. When the cover is rotated, the pin is urged against the groove to selectively extend or retract the connector from the casing. In another aspect, the cover is pivotally interconnected with the circuit board, and when the cover is rotated, the casing selectively translates with respect to the circuit board to expose or cover the connector.
US08246357B2 Electrical connector
An electrical connector. In one embodiment of the present invention, the electrical connector includes a first main body, including a first insulating body and a first conductive member set fixed to the first insulating body, in which each conductive member of the first conductive member set includes a first internal connecting portion; and a second main body, including a second insulating body and a second conductive member set fixed to the second insulating body, in which each conductive member of the second conductive member set includes a second internal connecting portion, and the second internal connecting portion of each conductive member of the second conductive member set is in contact with the first internal connecting portion of the corresponding conductive member of the first conductive member set respectively. The second main body is movably mounted on the first main body and is capable of rotating relative to the first main body, and during rotation, each of the second internal connecting portions is maintained in contact with the corresponding first internal connecting portion.
US08246356B2 Magnetic flux viewer
In an embodiment, the claimed invention is a device to for optical presentation of magnetic flux. A ferromagnetic colloidal mixture is substantially evenly dispersed and sealed between two optically transmissive lenses. At least one magnetic source is juxtaposed about the viewer. A light source is positioned to project through the mixture, the light interacting with the mixture to create the presentation of magnetic flux. The viewer is optionally positioned within a housing. In another embodiment, the invention is a method of using the viewer to view a presentation of magnetic flux when light interacts with the mixture.
US08246352B2 Surgical guide and a method for positioning a drill using the surgical guide
Provided is a surgical guide that enables a dentist to visually identify the tip of a drill during dental implant treatment, and does not allow the drill to tilt more than necessary, and enables sufficient cooling water to be provided so as not to cause bone burns, and is compatible with several different types of drills having different diameters. A first wire is embedded in a mockup in a same orientation as the orientation of a fixture of an implant is to be embedded. A guide member of a surgical guide is fitted to a tooth portion of the mockup. An adjusting mechanism adjusts such that an intersection line made by plane-shaped red laser light beam and green laser light beam from line laser modules is located on the first wire. The guide member is removed from the tooth portion of the mockup, and fitted to a tooth portion in the mouth, and the orientation of a drill is aligned with the intersection line. Drilling operation is performed in the aligned condition.
US08246351B2 Positioning method for orthodontic appliance and structure thereof
A positioning method for orthodontic appliance and structure, mainly provided with base units molded by plastic injection. During the fabricating process, a crossed reference line is first drawn on a dental mold of the patient, after heating, the orthodontic appliance is embedded to the base unit, and a flexible member is used to bind and fixedly position the orthodontic appliance. Each of the aforementioned base units together with the orthodontic appliance is attached to the dental mold, and then light curing composite resin is attached to each of the base units. Accordingly, after applying an adhesive layer to each of the orthodontic appliances, each of the series connected base units together with the orthodontic appliances bound to the base units is directly attached to the respective teeth portion of the patient requiring straightening, thereby enabling fitting of orthodontic appliances to be more convenient and providing a more efficient fabricating process.
US08246348B2 Self-ligating orthodontic bracket
A self-ligating orthodontic bracket with a replaceable closing spring member detachably connected to the upper structure of a tooth-attachable base member. Particular preferred embodiments relate to the form of detachable connection of the closing spring member with the upper structure, with one particularly preferred embodiment being torsion tabs that are reversibly deformable to maintain pivoting engagement of spring member and upper structure when desired and easy removal of the spring members when desired.
US08246347B2 Low profile self-ligating orthodontic brackets and methods of using such orthodontic brackets
Low profile self-ligating orthodontic brackets and methods of using such orthodontic brackets. The bracket includes a bracket body, a latching member, and a hinge pin pivotally coupling a hinged end of the latching member with the bracket body. The hinge pin, which is made of a resilient material, is configured to flex so that a portion of the latching member can be engaged with a recess defined in the bracket body to couple the non-hinged end of the latching member with the bracket body.
US08246342B2 Injection moulding device
An injection molding nozzle (10) for injection molding equipment and comprising a nozzle casing (14) subtending a longitudinal axis (L) fitted with at least one flow duct (18) for a fluid processing material, further comprising at least one nozzle tip (24) discharging the fluid processing material out of the nozzle casing (14), the minimum of one nozzle tip (24) running transversely to the longitudinal axis (L) of the nozzle casing (14), the minimum of one nozzle tip (24) being integral with the nozzle casing (14).
US08246340B2 Light guide plate injection molding die
A injection molding die includes a first molding unit, a second molding unit, at least one slide block, and a number of elastic elements disposed between the slide block and the first molding unit. The first molding unit includes a first molding surface and a sidewall surrounded the first molding surface. At least one gap is defined in an edge between the sidewall and the first molding surface. The gas hole is exposed at the gap for providing gas to the gap. The slide block is capable of moving toward or away from the sidewall, and includes a protrusion for engaging in the gap to cover the gas hole. The protrusion includes a protrusion surface coplanar with the first molding surface. The second molding unit includes a second mold surface defining a mold cavity cooperated with the first molding surface, the protrusion surface, and the at least one slide block.
US08246339B2 Door skin, a method of etching a plate, and an etched plate formed therefrom
The present invention relates to a door skin comprising an exterior surface having outer portions lying on a first plane, spaced grooves recessed from the plane of the outer portions, and tonal portions having a planar area and a plurality of spaced depressions recessed from the plane of said planar area. The present invention is also directed to a method of etching a plate, for use with a molded die set, for embossing a wood grain pattern in the door skin, and the etched plate formed therefrom.
US08246333B2 Rotor profile for a screw compressor
A rotor profile for a screw compressor includes a male rotor and a female rotor, which are operated in an operation space while being engaged with each other, wherein a rotor profile of the female rotor includes a curve having an operation contact point located around a pitch circle at a following-side of the female rotor, the operation contact point being contacted with the male rotor to operate the male rotor when the female rotor is operated, and the curve is configured with a quadratic function y=Lx2+Mx+N. Here, the constants L, M and N are values determined such that a slip ratio at the operation contact point is minimized. This rotor profile for a screw compressor minimizes a slip ratio at the operation contact point, thereby decreasing abrasion and reducing noise of the compressor.
US08246332B2 Rotor for a vane pump, made of plastic material reinforced by metallic foil
A rotor (1-3) molded of plastic material, intended for rotary installation in a cavity of a pump body and for reception of one or more vanes forming the pumping members, characterized in that at least a part of the surfaces thereof, intended to undergo sliding displacements against other pump members, is covered by at least one metallic foil (4) caused to adhere to the subjacent surface of plastic material. The metallic foil can consist of a steel sheet or an aluminum alloy sheet, intended for reducing the resistances to the sliding as well as for mechanically reinforcing the rotor. The metallic foil can be fastened to the plastic material body (1) of the rotor by a co-molding operation, or it can be mechanically fixed to the body (1) of the rotor molded of plastic material.
US08246331B2 Scroll fluid machine with a pin shaft and groove for restricting rotation
A fixed scroll is provided with a pin shaft portion which is formed in a cylindrical shape. Formed in a movable scroll is a slide groove which extends in the radial direction of the movable scroll. The pin shaft portion of the fixed scroll is engaged into the slide groove of the movable scroll. During orbital movement of the movable scroll, the pin shaft portion slidingly contacts a side surface of the slide groove, whereby rotation of the movable scroll is restricted.
US08246329B2 Fan
A fan includes a bracket, a stator, a rotor, and a slanting portion. The bracket includes a tray, and a frame circling the tray. The stator is mounted to and circled by the frame. The rotor includes a shaft rotatably mounted to the stator, and a shell coupled to the shaft. The shell covers the stator, and the shell and the tray of the bracket cooperatively enclose the stator. An assembly clearance is formed between a bottom end of the shell and a top surface of the tray. The slanting portion circles the tray and extends down from the bottom end of the shell, slanting away and spaced from the tray.
US08246323B2 Programmable logic controlled liquid pressurization device incorporating low energy consumption mechanisms for the utilization of solar energy
A liquid pressurization device which is housed within a single rectangular housing that utilizes a solar panel as the front cover and the only source of energy. An interchangeable pulley mounted on a motion controlled technology motor allows for a wide range of pressure and volume scenarios common to liquid pressurization applications, and in combination with a motor controller and driver board, and programmable logic control board, these pressure and volume scenarios are further optimized for the utilization of solar energy as the sole energy source. Said programmable logic board further provides ports for firmware updates, monitoring devices, and diagnostic devices. A lever is reciprocated by an energy transfer pulley that transfers drive force to the liquid end of the apparatus, providing a low friction multiplication of available power. The liquid end of the apparatus is further designed for ease of maintenance to replaceable components with limited life spans.
US08246319B2 Reciprocating pump
The reciprocating pump for performing a pumping action by reciprocating an individual reciprocating member inside a plurality of cylinder sections arranged in parallel includes a seal case in which a cylinder section is formed and which functions as an independent pressure-resistant container; and a suction valve and a discharge valve in which a valve chamber is formed individually and each of which functions as an independent pressure-resistant container. The suction valve and the discharge valve are coupled so as to sandwich two planar sections from a direction perpendicular to a direction in which a plurality of cylinder sections are arranged in parallel in a state in which each of the suction valve and the discharge valve abuts against the respective one of the two planar sections of an external surface of a small diameter section at a front end side formed in the seal case, and the valve chamber is communicatively connected to the cylinder section. Thereby, the cylinder distance can be reduced while maintaining the thickness between cylinders and the assembling is facilitated.
US08246318B2 Water-cooled air compressor
Provided is a water-cooled air compressor which is capable of restraining lowering of the performance of a plate type compressor for heat-exchanging compressed air from a compressor body, with cooling water due to clogging of gaps between plates in the heat-exchanger by dust or the like, incorporating a first solenoid valve and a second solenoid valve connected respectively in a cooling water supply pipe line and a cooling water discharge pipe line of the heat-exchanger, an air feed pipe line connecting between a compressed air supply pipe line on the outlet side of the heat-exchanger and the cooling water discharge pipe line, a third solenoid valve and a check valve connected in the air feed pipe line, a discharge pipe line connected in a discharge pipe line 18 so as to branch therefrom, a fourth solenoid valve connected in the discharge pipe line, and a control device for controlling opening and closing of the first to fourth solenoid valves.
US08246317B2 Fan assembly
A fan assembly for creating an air current includes a base having an air inlet and an air outlet, the base housing an impeller and a motor for rotating the impeller to create an air flow passing from the air inlet to the air outlet. The fan assembly further includes a vertically oriented, elongate annular nozzle including an interior passage having an air inlet for receiving the air flow from the base and a mouth for emitting the air flow, the nozzle defining an opening through which air from outside the fan assembly is drawn by the air flow emitted from the mouth.
US08246316B2 Vacuum source and float valve for a self-priming pump
A self priming pump system that includes a motor coupled to a centrifugal pump. A separator having a reservoir is provided for storing a limited amount of pumped fluid in advance of the centrifugal pump. A vacuum source provides a vacuum suction to the reservoir to draw pumped fluid into the reservoir to prime the pump. A float may be provided, wherein when the fluid level in the reservoir reaches a desired level, the float opens a float valve to let air into the reservoir to maintain the desired level. The float valve may have a capacity that is greater than or equal to the pumping capacity of the vacuum pump, or at least large enough to make up for a difference between the pumping capacity of the vacuum pump and an amount of fluid that can be pumped by the centrifugal pump from the reservoir.
US08246315B2 Drip pump system
A system and method for pumping an underground drip includes a pump barrel housing with a plunger and an elongated stroke actuator cylinder sealed to the pump barrel that vertically reciprocates the plunger. The pump barrel and plunger are preferably vented to avoid vacuum lock during pumping. The plunger pumps the fluid located in the drip upwardly to a low pressure tank or a pressurized surface vessel. A ball valve may be screwed onto the siphon line to allow for insertion and removal of the pump barrel and seals the siphon line if the pump is removed. A stuffing box seals the pump barrel to the upper end of the siphon line to prevent air from entering the system. The stuffing box also allows the pump depth to be easily adjustable by sliding the pump in until the pump tags bottom and then tightening at any point needed.
US08246311B2 Wind turbine rotor blade with variably actuatable porous window
A wind turbine blade includes a porous window defined in the suction side of the blade. The porous window includes a plurality of holes defined therein. An air manifold within the internal cavity of the blade is in airflow communication with the porous window. An inlet air passage in the pressure side of the blade is in communication with the air manifold. A deployable cover member is configured adjacent the porous window and is variably positionable from a fully closed position wherein airflow through the holes in the porous window is blocked to a fully open position wherein airflow is established through the holes in the porous window.
US08246310B2 Turbomachine fan
A turbomachine fan including blades mounted in slots at the periphery of a rotor disk, and inter-blade platforms having radial lugs for fastening to corresponding lugs of the disk is disclosed. Each platform is fastened to the disk by a pin inserted into orifices in the lugs of the platform and into corresponding orifices in the lugs of the disk.
US08246306B2 Airfoil for nozzle and a method of forming the machined contoured passage therein
A nozzle in which an airfoil includes a pressure surface and a suction surface that join at substantially opposing chordal ends of the airfoil to form a leading edge of the airfoil and a trailing edge of the airfoil. A trailing edge passage is defined through the airfoil through which coolant flows. The trailing edge passage is proximate to the trailing edge of the airfoil and has a contoured shape that conforms to that of the trailing edge.
US08246296B2 Aspirated impeller
In one embodiment, a centrifugal impeller is described having a front side with airfoils and a back side. A conduit may be formed between the front side and the back side, or any other side, and may convey pressurized working fluid between the two. The conduit may pass relatively high pressure working fluid between any two locations such as from the front side to the back side. The conduit may include an aperture located on the front side and an aperture located on the back side. Any number of conduits may be defined within the centrifugal impeller. Apertures located on the front side of the impeller may be formed in any suitable place, such as a hub of the impeller or an airfoil surface, to set forth just two non-limiting examples.
US08246288B2 Manipulator
A manipulator includes a support arm, a grasping member, and a connecting assembly. The connecting assembly connects the support arm with the grasping member. A base is fixed to the support arm, and the holder is fixed to the base. The holder defines an assembling hole, and a perimeter of the assembling hole increases along a direction towards the base. The connecting member has a first assembling portion received in the assembling hole of the holder. The elastic member is positioned between the base and the connecting member, thus producing an elastic force to drive the connecting member to resist the holder.
US08246286B2 Loader work apparatus
A work apparatus to be mounted to a work vehicle includes: a pair of cylindrical masts 35 disposed erect on right and left sides of a vehicle body having a control valve; a boom 91 pivotally supported to the masts; an implement pivotally supported to the boom; a boom cylinder 60 for pivoting the boom; an implement cylinder 61 for operating the implement; a boom piping system communicating the control valve with the boom cylinder; and an implement piping system communicating the control valve with the implement cylinder; wherein a channel constituting member 84 constituting the boom piping system extends vertically within each mast; one end of the channel constituting member 84 extends to the outside at a lower portion of the mast to be connected with the control valve; and the other end of the channel constituting member 84 extends to the outside at an upper portion of the mast 35 to be connected with boom cylinder 60.
US08246284B2 Stacked load-lock apparatus and method for high throughput solar cell manufacturing
An apparatus with a plurality of load-lock chambers stacked having independently controlled pressures within their interior regions is provided. According to one or more embodiments, each load-lock chamber includes a pump valve connected to a pump line and a vent valve connected to a vent line to independently control the changes of pressure within the interior regions of the chambers. Methods for conveying substrates held within these chambers from the apparatus to one or more processing chambers, which may be in-line, are also provided.
US08246283B2 Equipment and method for transporting red-hot coke
Equipment and a method for transporting red-hot coke are provided, which do not need increase in size of a hoist, reinforcement of a CDQ system, and the like, even when the amount capacity of a coke bucket does not correspond to an amount equivalent to the coke amount from one oven chamber. In particular, transporting equipment for red-hot coke, includes: a non-rotary coke receiving car for receiving coke out of a coke oven; a coke bucket for receiving the coke discharged from the coke receiving car; a transporting device for transporting the coke bucket to a hoist position; and a hoist for transporting the coke bucket to a coke dry quenching system.
US08246279B2 Tight-space drilling product
A tight-space drilling product for drilling in a confined space between a workpiece and an opposite surface includes a drilling implement with a confined space configuration where the drilling implement contacts both the workpiece and the opposite surface.