Document Document Title
US10533304B2 System and methods for controlled lowering and lifting of a load
A system and method for the controlled lowering and lifting of a load are disclosed. The system and method may include operating a work machine having a hydraulic system including a hydraulic actuator for supporting a load, a first control valve in fluid communication with the actuator, and a controller for operating the first control valve. In one embodiment, the controller includes a first algorithm for operating the first control valve in a load lowering operation. When an operational fault within the hydraulic system is detected, the controller can be configured to enter into a safe lowering mode. In the safe lowering mode, the first algorithm is disabled and a pulse width modulation (PWM) current is sent from the controller to the first control valve. A user interface is provided to allow an operator to control the PWM current duty ratio to allow the load supported by the actuator to be lowered.
US10533303B2 Construction machine to adjust operation reaction force of an operating lever
A construction machine includes a control device having a reaction-force correction control section. When a difference between a target operator input and an actual operator input for a front member exceeds a preset range, the reaction-force correction control section executes correction to increase an operation reaction force to be applied by a reaction-force applying device to an operating unit operating an actuator driving the front member. When the difference falls within the range, the reaction-force correction control section executes correction to decrease the operation reaction force to be applied by the reaction-force applying device to the operating unit operating the actuator driving the front member.
US10533302B2 Construction machine
A construction machine includes a machine body, a walkway 30 formed on an upper surface of a lateral one side of the machine body, and a handrail 36 configured to be height-variable by a fixed rail body 50 provided standing along the walkway 30 on the lateral one side on the upper surface of the machine body and a movable rail body 70 attached rotatably to an upper end portion of the fixed rail body 50 and foldable with respect to the fixed rail body 50. The fixed rail body 50 has a plurality of struts 51 that each having a bent shape such that an upper portion is located more laterally outward than a lower portion. A mirror 45 is attached to the strut 51. The mirror 45 is disposed laterally outward than the lower portion of the strut 51 and within a width of the machine body, and is disposed between the struts 51, below an upper end portion of the fixed rail body 50, and above a rotation tip portion of the movable rail body 70 after folded. In such a configuration, attaching the mirror to the foldable handrail to secure a lateral visibility neither result in interfering with folding of the handrail nor result in constituting obstacles to transporting, to the walkway, and to a cover opened/closed at maintenance.
US10533301B1 GPS and laser grading control
A hydraulic control system for an earth-moving vehicle with an automatic grade control system that hydraulically powers the height of the blade through the hydraulic accessory port. When using a laser based system the main arms are controlled through the accessory port and a pitch movement of the blade is limited. When using a GPS based system the accessory hydraulic is disconnected from the main arm and reconnected to the pitch hydraulic to affect the height of the blade.
US10533298B2 Working machine
A working machine includes: a boom base portion including: an inner side wall; and an outer side wall disposed opposite to the inner side wall; a lift link disposed on a rear portion of the boom base portion; and a boom cylinder disposed in front of the lift link. One end side of the lift link is inserted between the inner side wall and the outer side wall and is pivotally supported on the boom base portion. The other end side of the lift link is pivotally supported on the machine body. One end of the boom cylinder is inserted between the inner side wall and the outer side wall in front of the lift link and is pivotally supported on the boom base portion. The other end of the boom cylinder is pivotally supported on the machine body by below the lift link.
US10533297B2 Caisson block construction method and caisson block structure
A caisson block construction method, including: manufacturing a plurality of bottom caisson blocks having a plurality of first unit compartments disposed consecutively in a horizontal direction; manufacturing a plurality of upper caisson blocks having a plurality of second unit compartments; forming a bottom caisson block structure by installing the plurality of bottom caisson blocks side by side in the horizontal direction; installing the plurality of upper caisson blocks above the installed bottom caisson blocks; filling with rubble the second unit compartment of the upper caisson block positioned above the first unit compartment for rubble and exposed upward; inserting a vertical reinforcing bar module after the upper caisson blocks are installed; and forming a vertical concrete column for joining by casting concrete into the upper part of the second unit compartment in which the vertical reinforcing bar module is inserted.
US10533296B2 System and method for controlling land deformation, and method for optimal design of well in system for controlling land deformation
Disclosed are a system and method for controlling land deformation, and a method for optimal design of a well in a system for controlling a well in a system for controlling land deformation. The land deformation control system with respect to a land including an confined aquifer and an aquiclude above the confined aquifer includes a first well for water pumping from or water injecting into the confined aquifer; and one or more second wells spaced apart from the first well by a predetermined distance and having a lower end portion positioned in the aquiclude, wherein a water level of the second well is maintained at a preset water level value to control an amount of change in water head of the aquiclude, which drops due to pumping of the confined aquifer or rises due to injection with respect to each of the second wells.
US10533291B2 Snow melting mat
The snow melting mat includes an elongate, substantially flat sheet of a desired length connected to a recirculation header at one end and a circulation header at the opposite end. The sheet includes a plurality of channels defined inside the sheet. The channels permit heated liquid to circulate along the length of the sheet. A heater-pump heats the liquid that maintains the temperature of the sheet at several degrees above freezing and pumps the liquid through the recirculation header, the sheet, and the circulation header. A plurality of transverse grooves is formed on the top of the sheet to provide a gripping, walking surface. The grooves taper in depth to permit melted snow and ice to run off the sides of the sheet. Couplers and joints permit multiple sheets to be joined together in any desired pattern.
US10533290B2 Continuous flow city
A roadway system of sinusoidal one-way roads which surround individual developed areas. A straight bidirectional road intersect the sinusoidal roadways at locations in which the sinusoidal roadways are substantially tangent to one another and orthogonal to the bidirectional road.
US10533289B2 Metamaterial null flux magnet bearing system
Non-contact bearing system, such as a magnetic levitation system, having a geometry. The geometry includes a plurality of track elements arranged to nest together in a length direction. The plurality of track elements are shaped to define at least an upper and a lower null flux crossing and the plurality of nested track elements form a conductive metamaterial. Method for constructing a metamaterial null flux magnetic levitation track with tessellating elements of stamped conductors.
US10533288B2 Railroad track wire connection and corresponding railroad installation
The railroad track wire connection is configured for electrically connecting a first element of a railroad installation to a second element of the railroad installation, the first element and the second element being electrically conductive, at least one of the first element and the second element being a rail of a line of rails of a railroad track of the railroad installation. The railroad track wire connection comprises at least one first element wire having a proximal end for connection to the first element and a distal end, a first element connector provided at the distal end of each first element wire, the first element connector being configured for electrical connection with the second element directly or via a mating second element connector, wherein the first element connector comprises a magnetic element for generating a magnetic force with the second element for fixing the first element connector to the second element in a removable manner or with a magnetic element of the second element connector for fixing the first element connector to the second element connector in a removable manner.
US10533287B2 Dispersant for carbon fibers, carbon fiber dispersion composition, and method for manufacturing carbon fiber sheet
Provided is a dispersant for carbon fibers which allows uniform dispersion of relatively long carbon fibers, e.g., carbon fibers with a length of 12.5 mm or more, particularly 10.0-100.0 mm, more particularly 12.5-50.0 mm in an aqueous medium.A dispersant for carbon fibers used by combining: (A) a random copolymer of phenylglycidyl ether and ethylene oxide, or a random copolymer of phenylglycidyl ether, ethylene oxide and propylene oxide; and (B) a polyether-based polyurethane resin based on a bifunctional polyol and hexamethylene diisocyanate, the bifunctional polyol being polyethylene glycol and/or an ethylene oxide-propylene oxide random copolymer.
US10533281B2 Method for separating and breaking down biodegradable and non-biodegradable materials
A method for breaking down a pallet of plastic, paper, cardboard, and organic material to produce bio-gas, fertilizer, and water includes a step of maintaining a negative pressure during the steps of removing, separating, recycling, feeding, and converting to clean odorous air. The step of maintaining the negative pressure is further defined as removing the odorous air generated during the steps of separating, recycling, feeding, and converting. The chamber of the biofilter is maintained at a predetermined humidity of at least 80% and a predetermined temperature of between 70° F. and 80° F. A biofilter for removing odorous air includes a filter media having a mixture of woodchips having hardwood chips being present between 30 wt. % and 50 wt. %, softwood chips being present between 50 wt. % and 70 wt. %, and microorganisms disposed therein.
US10533280B2 Special-shaped cable core forming mechanism
A layer of wires is preliminarily stranded by a layer of strand-through holes, and a first strand cylinder is used for the second pressing and stranding. The next layer of special-shaped single wires is stranded through a second pre-stranding assembly, and then the last layer of wires is stranded through a main stranding mold, thus stranding a plurality of layers at the same time with a compact structure. The outer circumference of the guide roller matches that of the special-shaped single wire, avoiding the reduced quality of stranded cable core. The first rotating connector is bowl-shaped and is provided with a layer of strand-through holes together with a structure in which a first pull rod is in fit with the rotating connector and a structure in which a second pull rod is in fit with the rotating connector.
US10533275B2 Control method of a laundry machine
A laundry machine and a control method thereof are provided in which laundering ability may be improved while also improving efficiency and noise/vibration. The laundry machine employs a plurality of drum motions by varying drum rotational speed, drum rotational direction, and drum starting and stopping point, to provide different motion of laundry items in the drum.
US10533274B2 Washing machine
Disclosed herein is a washing machine having a tub, a screen provided inside the tub to support laundry, a nozzle assembly having a plurality of washing medium spraying nozzles configured to spray washing medium toward the laundry and being movable, a driver configured to move the nozzle assembly, and a washing medium supply configured to supply the washing medium to the nozzle assembly. The washing machine may efficiently perform anhydrous washing when dry ice snow or liquefied nitrogen is used as a washing medium.
US10533272B2 Washing machine appliance and method of operation
A washing machine appliance and method of operation are generally provided herein. The washing machine appliance may include a cabinet, a first pair of diagonal feet, a second pair of diagonal feet, a tub, a basket, a measurement device, a motor, and a controller. The motor may be configured for selectively rotating the basket within the tub. The controller may be in operative communication with the motor and the measurement device. The controller may be configured for rotating the basket for a first period, monitoring movement of the cabinet between the first pair of diagonal feet and between the second pair of diagonal feet during the rotating, determining a first diagonal movement value, determining a second diagonal movement value, evaluating one or both of the diagonal movement values against a predetermined value, and transmitting a stability signal.
US10533269B2 Textile, garment including the textile, and methods for manufacturing the textile and the garment
A textile is provided that includes a plurality of warp yarns and a plurality of weft yarns woven together, the plurality of warp yarns each including an elastic warp filament and a non-elastic warp filament, and the plurality of weft yarns each including an elastic weft filament and a non-elastic weft filament. At least one of the elastic warp filament, the non-elastic warp filament, the elastic weft filament, and the non-elastic weft filament includes a hydrophobic material. The materials of the elastic warp filament, the non-elastic warp filament, the elastic weft filament, and the non-elastic weft filament are selected such that the textile has a high elastic stretchability in at least one of a weft direction and a warp direction. A garment including the textile, and methods for manufacturing the textile and the garment, are also disclosed.
US10533266B2 Layered carbon fiber
A carbon nanotube yarn is coated with polyacrylonitrile to form a coated carbon nanotube yarn. The polyacrylonitrile is converted to crystalline carbon to form a layered carbon fiber with a sheath of the crystalline carbon and a core of the carbon nanotube yarn.
US10533263B2 Method for continuous electrolytic etching of grain oriented electrical steel strip and apparatus for continuous electrolytic etching of grain oriented electrical steel strip
Method for continuous electrolytic etching of a grain oriented electrical steel strip includes: forming an etch mask on a surface of a grain oriented electrical steel strip cold-rolled to final thickness with a linear exposed portion exposed from the etch mask; centering the grain oriented electrical steel strip with a position sensor and centering apparatus, which are placed immediately upstream of an electrolytic etching apparatus; and performing an electrolytic etching process in which electrolytic etching is performed in the electrolytic etching apparatus to form a linear groove on the surface of the grain oriented electrical steel strip by passing electric current between a conductor roll and electrode placed in an electrolytic bath while the grain oriented electrical steel strip is brought into contact with the conductor roll, the grain oriented electrical steel strip is immersed in the electrolytic bath and the grain oriented electrical steel strip is facing the electrode.
US10533262B2 Plating apparatus, substrate holder, plating apparatus controlling method, and storage medium configured to store program for instructing computer to implement plating apparatus controlling method
Provided is a plating apparatus for plating a substrate by using a substrate holder including an elastic projection that seals a to-be-plated surface of the substrate, the plating apparatus comprising a measurement device configured to measure a deformed state of the elastic projection by measuring at least either one of a compression amount of the elastic projection and load applied to the elastic projection at a time when the substrate physically contacts the elastic projection of the substrate holder; and a controlling device configured to make a judgment on the basis of the measured deformed state as to whether sealing by the elastic projection is normal.
US10533258B2 Method of making Co3O4 nanorods for electrocatalytic water splitting
A method of making Co3O4 nanorods by thermal decomposition of a cobalt salt is described. A method of using Co3O4 nanorods as an electrocatalyst component to a porous carbon electrode is also described. The carbon electrode may be made of carbonized filter paper. Together, this carbon-supported Co3O4 electrode may be used for water electrolysis.
US10533257B2 Photochemical electrode and hydrogen evolution device
A photochemical electrode includes a conductive oxide. Fermi energy of the conductive oxide is higher than a first energy minimum of a first band having a lowest energy and is lower than a second energy minimum of a second band having a higher energy than the first band among bands whose curvatures are positive in reciprocal space. The first energy minimum and the second energy minimum are at the same point of wave vector. A difference between the second energy minimum and the first energy minimum is not less than 1 eV nor more than 3 eV, and is smaller than a difference between the first energy minimum and an energy maximum of a band having a highest energy among bands whose curvatures are negative.
US10533256B2 Hydrophobic coatings for metals incorporating anodic and rare-earth oxides and methods of applying same
A hydrophobic coating and a method for applying such a coating to a surface of a metallic substrate. The method can include anodizing a nanoporous layer of anodic metal oxide on the surface; cathodizing yttrium oxide nanoparticles onto the surface; applying a hydrophobic ceramic coating composition to the surface by an application method selected from the group consisting of: flowing, dipping, and spraying; and heating the coated surface at a cure temperature from about 150° C. to about 300° C. for at least 2 hours.
US10533255B2 Slurry formulations for formation of reactive element-doped aluminide coatings and methods of forming the same
Novel slurry formulations and processes for forming improved protective coatings used in the hot section components of gas turbine engines are provided. The process includes a unique two-step deposition methodology whereby the required concentration of reactive element within an improved reactive element doped aluminide coating can be consistently produced in a reproducible manner.
US10533252B2 Showerhead, semicondcutor processing apparatus having the same and semiconductor process
A showerhead is configured to be mounted inside a processing chamber and provide a processing gas onto a semiconductor wafer inside the processing chamber. The showerhead includes a supply plenum, a faceplate, and an electrode plate assembly. The faceplate is disposed at a side of the supply plenum. The electrode plate assembly is disposed between a gas source and the supply plenum. The electrode plate assembly includes a first plate having a unitary construction and having a plurality of first gas holes, and a second plate having a unitary construction and having a plurality of second gas holes. The second plate is located between the first plate and the supply plenum and separated from the first plate. The plurality of second gas holes are partially overlapped but misaligned with the plurality of first gas holes. A semiconductor apparatus having the same and a semiconductor process are also provided.
US10533251B2 Actuator to dynamically adjust showerhead tilt in a semiconductor processing apparatus
A showerhead module adjustment mechanism is provided which supports a showerhead module in a top plate of a semiconductor substrate processing apparatus, the showerhead module adjustment mechanism being dynamically operable to adjust a planarization of a faceplate of the showerhead module with respect to an upper surface of a substrate pedestal module adjacent the faceplate in the semiconductor substrate processing apparatus.
US10533250B2 Method of manufacturing semiconductor device
Described herein is a technique capable of improving a quality of a film formed on a substrate. According to the technique described herein, there is provided a method of manufacturing a semiconductor device, including: (a) exhausting an inner atmosphere of a first gas supply pipe configured to supply a first gas generated by a vaporizer to a process chamber accommodating a substrate by a first gas discharge system connected to the first gas supply pipe; (b) exhausting an inner atmosphere of the vaporizer through a second gas discharge system provided at a vaporizer outlet pipe of the vaporizer by supplying an inert gas to the vaporizer via a vaporizer inlet pipe of the vaporizer; and (c) supplying the first gas generated by the vaporizer to the process chamber accommodating the substrate via the vaporizer outlet pipe, the first gas supply pipe and a first timing valve provided at the first gas supply pipe before (a) is performed or after (b) is performed.
US10533249B2 Method of forming a self-cleaning film system
A method of forming a self-cleaning film system includes depositing a fluorinated material selected from the group consisting of fluorinated organic compounds, fluorinated inorganic compounds, and combinations thereof onto a substrate to form a first layer. The method includes removing a plurality of portions of the first layer to define a plurality of cavities in the first layer and form a plurality of projections that protrude from the substrate. The method includes depositing a photocatalytic material onto the plurality of projections and into the plurality of cavities to form a second layer comprising: a plurality of bonded portions disposed in the plurality of cavities and in contact with the substrate, and a non-bonded portion disposed on the plurality of projections and spaced apart from the substrate. The method also includes, after depositing the photocatalytic material, removing the non-bonded portion to thereby form the self-cleaning film system.
US10533248B2 Method of manufacturing sputtering target and sputtering target
The manufacturing cost of a sputtering target is reduced and the impurity concentration of the manufactured sputtering target is also reduced. A method of manufacturing a sputtering target includes: surface-treating at least one of a used sputtering target and a scrap material; melting at least one of the used sputtering target and the scrap material after the surface treatment to form an ingot; and manufacturing a sputtering target by subjecting the ingot to forging, rolling, heat treating, and machining.
US10533245B2 Mask assembly, method of manufacturing thereof, and apparatus including the same
A mask assembly, and an apparatus including the same are provided. The mask assembly includes a mask sheet. The mask sheet includes a pattern portion having openings, and a welding portion connected to the pattern portion. The welding portion has a grain size different from a grain size of the pattern portion.
US10533244B2 Method of producing hot forged product using brass and hot forged product and wetted product such as valve and water faucet molded using the same
To contribute to an improvement in a dezincification resistance of a copper alloy, focusing attention on a relation between a dezincification resistance of a copper alloy and the crystal grain size of an α phase, and the specific object is to provide a method of producing a hot forged product using a lead-free brass capable of ensuring corrosion resistances such as a prescribed dezincification resistance and the like even at sites of different thickness and shape, a hot forged product, and a wetted product such as a valve and a water faucet, molded using the same. A method of producing a hot forged product using a brass, comprising heat-treating a raw material to be subjected to forging work using a brass having a composition containing at least 59.2 to 63.0% by mass of Cu, 1.00 to 2.00% by mass of Sn and 0.05 to 0.25% by mass of Pb and containing the residue composed of Zn and inevitable impurities at a heating rate of 5.2° C./s or more from 350° C. until reaching the forging temperature.
US10533241B2 Hot-rolled steel sheet for high strength galvanized steel sheet, having excellent surface quality, and method for producing same
The present invention relates to a hot-rolled steel sheet for a high strength galvanized steel sheet, having excellent surface quality, and a method for producing the same, the hotrolled steel sheet comprising, by weight %: C: 0.08 to 0.2%, Si: 0.03 to 0.15%, Mn: 1.4 to 2%, P: 0.001 to 0.05%, S: 0.001 to 0.03%, Al: 0.002 to 0.05%, and the remainder being Fe and unavoidable impurities. The weight ratio of Mn/Si is 20 to 30, the weight ratio of C/Si is 1 to 5, and the weight ratio of Si/P is 3 to 10. The hot-rolled steel sheet has a microstructure consisting of, in area fraction, 10 to 40% of bainite, 20 to 30% of pearlite and 40 to 60% of ferrite, and includes a ternary eutectic compound of FeO, Fe2SiO4 and Fe3(PO4)2 formed within 50 μm from the surface.
US10533235B2 Hot-working tool material, method for manufacturing hot-working tool, and hot-working tool
A hot-working tool material has an annealed structure and is to be quenched and tempered before using, wherein: the hot-working tool material has a composition from which a martensite structure can be prepared by the quenching; and, in ferrite crystal grains in the annealed structure in a cross section of the hot-working tool material, the ratio by number of ferrite crystal grains having a largest diameter (L) of 100 μm or more is not more than 10.0% relative to the total ferrite crystal grains, and the ratio by number of ferrite crystal grains having an aspect ratio (L/T) [wherein (L) stands for a largest diameter, and (T) stands for the largest transverse width orthogonally crossing the same] of 3.0 or more is not more than 10.0% relative to the total ferrite crystal grains.
US10533233B2 Method for treating lignocellulosic materials
A method of generating a refined sugar stream that comprises xylose from a biomass hydrolysis solution including contacting a biomass hydrolysis solution that includes a population of mixed sugars comprising xylose, an acid, and impurities, with an extraction solvent to form an extraction mixture; and separating from said extraction mixture a first stream that includes the acid and a second, refined sugar stream that includes the extraction solvent and xylose. The extraction solvent is a tri-alkyl phosphine oxide, a dialkylsulfoxide, or a dialkylphosphite, or any combination thereof.
US10533228B2 3.beta-hydroxysteroid dehydrogenase in steroid dependent disease
Methods and kits for characterizing a subject having a steroid-dependent disease such as prostate cancer are described. A method of treating a steroid-dependent disease in a subject by obtaining a biological sample from the subject, determining if the HSD3B1(1245C) gene or 3βHSD1(367T) protein is expressed in the biological sample, and providing treatment other than or in addition to steroid ablation to the subject if the HSD3B1(1245C) gene or 3βHSD1(367T) protein is expressed is also described.
US10533223B2 Detection of target nucleic acids using hybridization
The present invention provides detection systems and methods for detection of loci and genomic regions in a sample, including mixed samples, using hybridization to an array.
US10533219B2 Compositions and methods for identifying nucleic acid molecules
The present disclosure provides methods and compositions for sequencing nucleic acid molecules and identifying individual sample nucleic acid molecules using Molecular Index Tags (MITs). Furthermore, reaction mixtures, kits, and adapter libraries are provided.
US10533218B2 Methods and systems for nucleic acid amplification
The disclosure provides methods and systems for nucleic acid amplification including isothermal nucleic acid amplification.
US10533216B2 Oligonucleotide probe inversion process for in situ synthesized probe arrays
The present disclosure relates to processes for inverting oligonucleotide probes in an in situ synthesized array. These processes can be used to reverse the orientation of probes with respect to the substrate from 3′-bound to 5′-bound. These processes can also be used to reduce or eliminate the presence of truncated probe sequences from an in situ synthesized array.
US10533212B2 Nucleic acid target detection using a detector, a probe and an inhibitor
The present invention generally pertains to methods for detecting the presence or absence of a particular nucleic acid sequence. The present invention generally relates to incorporating a detector into a target nucleic acid, adding an oligonucleotide probe, polymerase enzyme and an inhibitor to the reaction, and detecting interference of the oligonucleotide probe with the inhibitor as an indication of the presence of a particular target nucleic acid sequence as well as kits encompassing the same.
US10533211B2 Coumarin compounds and their uses as fluorescent labels
The present application relates to new coumarin compounds and their uses as fluorescent labels. The compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.
US10533209B2 Immobilized enzymatic reactor
An immobilized enzymatic reactor can include a wall defining a chamber having an inlet and an outlet; a solid stationary phase covalently linked to an enzyme and disposed within the chamber; and a pressure modulator in fluid communication with the chamber and adapted to support continuous flow of a liquid sample comprising a polymer analyte through the inlet, over the solid stationary phase, and out of the outlet under a pressure between about 2,500 and 35,000 psi. In one example, the solid stationary phase includes inorganic/organic hybrid particles in an ultra performance liquid chromatography system, the enzyme is a protease, and the polymer analyte is a polypeptide. The immobilized enzymatic reactor can prepare an analyte for applications such as for hydrogen deuterium exchange mass spectrometry.
US10533205B1 Kaurenoic acid glycoside precursors and methods of synthesis
Ent-kaurenoic acid glycoside precursor compositions and synthesis methods are provided. The KA-19-monoside, KA-19-bioside and KA-19-trioside precursors can be used as starting materials for a variety of kaurenoic acid based reactions. The precursors provide alternative synthesis pathways for steviol glycosides to the natural pathway based on Steviol biosynthesis. The alternative synthesis pathways using the precursors also circumvent the rate limiting step of the natural Steviol biosynthesis pathway. The precursors can be used individually or in combination to produce a mixture or individual steviol glycosides such as Rebaudioside A, Rebaudioside D or Rebaudioside M. Control over the precursor quantities and composition allows control over the composition of the resulting steviol glycosides that are finally produced.
US10533204B2 Method for amplifying a T cell receptor (TCR) cDNA
As a method for highly efficiently amplifying a TCR cDNA in a short period of time, there is provided a method for amplifying a T cell receptor (TCR) cDNA, which comprises the following step (1) and step (2): (1) the step of performing PCR by using at least one kind of the L primer mentioned below, the C primer 1 or UTR primer 1 mentioned below, and cDNA obtained from a single cell as the template to obtain an amplification product 1; an L primer of 30- to 60-nucleotide length comprising an adapter part of 15- to 25-nucleotide length, and a leader region-annealing part of 15- to 25-nucleotide length, which is ligated downstream from the adapter part, and can anneal to a part of a leader region containing a translation initiation codon, or an upstream part thereof, a C primer 1 of 15- to 25-nucleotide length, which can anneal to a part of a constant region, or a UTR primer 1 of 15- to 25-nucleotide length, which can anneal to a part of a 3′ untranslated region; (2) the step of performing PCR by using the adaptor primer mentioned below, the C primer 2 or UTR primer 2 mentioned below, and the amplification product 1 as the template to obtain an amplification product 2; an adapter primer of 15- to 25-nucleotide length, which can anneal to the adapter part of the amplification product 1, a C primer 2 of 15- to 25-nucleotide length, which can anneal to a part of the constant region existing upstream from the region to which the C primer 1 anneals, or a UTR primer 2 of 15- to 25-nucleotide length, which can anneal to a part of the 3′ untranslated region existing upstream from the region to which the UTR primer 1 anneals.
US10533202B2 Enzymatic production of D-tagatose
The current disclosure provides a process for enzymatically converting a saccharide into tagatose. The invention also relates to a process for preparing tagatose where the process involves converting fructose 6-phosphate (F6P) to tagatose 6-phosphate (T6P), catalyzed by an epimerase, and converting the T6P to tagatose, catalyzed by a phosphatase.
US10533201B2 Enzymatic transphosphorylation of sugar substrates
The present invention relates to methods of producing sugar phosphates by enzymatic transphosphorylation, wherein the phosphoryl transfer from phosphate donor substrates to sugar substrates is catalyzed by an enzyme having alpha-glucose-1-phosphatase activity. Furthermore, the present invention relates to a biocatalyst having sucrose phosphorylase as well as alpha-glucose-1-phosphatase activity and its use. The production of an enzyme having alpha-glucose-1-phosphatase activity and its use in the transphosphorylation of sugar substrates is also presented herein.
US10533198B2 Methods and products for production of wax esters
The present invention relates to the provision of genetically modified fungal cells, such as yeast cells with an improved ability for producing different fatty acids and specifically fatty acid ethyl esters (FAEE), the main components of biodiesel. An increased in fatty acid production, and hence in FAEE, is obtained in the first place by expressing different heterologous polypeptides in combination with the down-regulation, attenuation, deletion or over-expression of specially selected genes, wherein said genes encode enzymes involved in the fatty acids synthesizing pathway, fatty acid consuming pathways, carbohydrate biosynthesis pathways or enzyme acting as wax ester transporters or a combination thereof. The methods and products of the invention would allow large-scale production of FAEE with carbohydrates as the only externally-supplied substrate.
US10533197B2 Method for culturing microorganism, and process for producing substance with microorganism
Using as a carbon source a long chain fatty acid which has not necessarily been efficaciously used in industry, culture of a microorganism and production of a substance by the microorganism are industrially efficiently carried out. A microorganism is cultured in the presence of a carbon source including anyone of the following compositions: (1) a fatty acid composition containing at least two fatty acids selected from the group consisting of lauric acid, myristic acid, palmitic acid and oleic acid; and (2) a mixed composition containing at least one fatty acid selected from the group consisting of lauric acid, myristic acid, palmitic acid and oleic acid, and a fat and oil, and having a content of the fatty acid of not less than 10% by weight.
US10533195B2 Processing biomass
Biomass (e.g., plant biomass, animal biomass, and municipal waste biomass) is processed to produce useful products, such as fuels. For example, systems can use feedstock materials, such as cellulosic and/or lignocellulosic materials and/or starchy or sugary materials, to produce ethanol and/or butanol, e.g., by fermentation.
US10533194B2 Systems and methods for enhancing microbial conversion of biomass using mechanical augmentation
A system and method for converting biomass with no chemical pretreatment is disclosed. Combination of a microbial system and the use of mechanical disruption during fermentation may help achieve high conversion rate without the extra cost and undesirable by-products typically associated with the pretreatment process.
US10533192B2 Production of isoprene by methane-producing archaea
Plasmid vectors and use of plasmid vectors in methods for producing methane and isoprene using Archaea are disclosed. Particularly, plasmid vectors that express isoprene synthase (ispS) are prepared and inserted into methanogens, such as Methanosarcina acetivorans, to allow for co-production of methane and isoprene. In one embodiment, the methods of the present disclosure can be used for wastewater management.
US10533189B2 Highly specific delivery of polynucleotides to the cell nucleus via compression
The subject invention pertains to delivering a polynucleotide into a target cell, particularly, into the nucleus of the target cell. The method comprises the steps of contacting the polynucleotide with the cell and applying pressure on the polynucleotide and the cell in a manner that forces the polynucleotide into the cell. The pressure can be between about 0.1 Pa to about 50 Pa; whereas, the polynucleotide is contacted with the cell at a concentration of between about 0.1 μM and about 100 μM. The method can be practiced for cells in culture or cells in vivo.
US10533188B2 Vectors with modified initiation codon for the translation of AAV-Rep78 useful for production of AAV
The present invention relates nucleic acid constructs for the production of recombinant parvoviral (e.g. adeno-associated viral) vectors in insect cells, to insect cells comprising such constructs and to methods wherein the cells are used to produce recombinant parvoviral virions. The insect cells preferably comprise a first nucleotide sequence encoding the parvoviral rep proteins whereby the initiation codon for translation of the parvoviral Rep78 protein is a suboptimal initiation codon that effects partial exon skipping upon expression in insect cells. The insect cell further comprises a second nucleotide sequence comprising at least one parvoviral (AAV) inverted terminal repeat (ITR) nucleotide sequence and a third nucleotide sequence comprising a sequences coding for the parvoviral capsid proteins.
US10533187B2 Methods and compositions for restoration of cone function in BCM
Provided are nucleic acid sequences, recombinant adeno-associated viral particles, compositions, and methods related to treating cone monochromacies, such as blue cone monochromacy (BCM). Specifically, the nucleic acid sequences, recombinant adeno-associated viral particles, compositions, and methods involve use of an M-opsin gene operably linked to a cone-specific promoter. Further disclosed is the sequence of a cone-specific PR2.1 promoter.
US10533185B2 Method for producing polyploidized megakaryocyte and platelets
An object of the present invention is to provide a method of promoting polyploidization of megakaryocytes and thereby producing highly polyploidized megakaryocytes, a method of efficiently producing platelets from polyploidized megakaryocytes, and the like. The present invention provides a method of producing polyploidized megakaryocytes comprising a step of forcing expression of an apoptosis suppressor gene in megakaryocytes before polyploidization and culturing the resulting cells.
US10533183B2 Oils, lipids and fatty acids produced in transgenic Brassica plant
The invention relates to a method for producing eicosapentanoic acid, docosapentanoic acid and/or docohexanoic acid in transgenic plants. According to said method, the plant is provided with at least one nucleic acid sequence coding for a polypeptide with a Δ6 desaturase activity, at least one nucleic acid sequence coding for a polypeptide with a Δ6 elongase activity, at least one nucleic acid sequence coding for a polypeptide with a Δ5 desaturase activity, and at least one nucleic acid sequence coding for a polypeptide with a Δ5 elongase activity, the nucleic acid sequence coding for a polypeptide with a Δ5 elongase activity being modified in relation to the nucleic acid sequence in the organism from which the sequence originates, such that it is adapted to the codon use in at least one type of plant. For the production of docosahexanoic acid, at least one nucleic acid sequence coding for a polypeptide with a Δ4 desaturase activity is also introduced into the plant.
US10533181B2 Fermentative glycerol-free ethanol production
The present invention relates to a yeast cell, in particular a recombinant yeast cell, the cell lacking enzymatic activity needed for the NADH-dependent glycerol synthesis or the cell having a reduced enzymatic activity with respect to the NADH-dependent glycerol synthesis compared to its corresponding wild-type yeast cell, the cell comprising one or more heterologous nucleic acid sequences encoding an NAD+-dependent acetylating acetaldehyde dehydrogenase (EC 1.2.1.10) activity. The invention further relates to the use of a cell according to the invention in the preparation of ethanol.
US10533180B2 Methods of producing 6-carbon chemicals via CoA-dependent carbon chain elongation associated with carbon storage
This document describes biochemical pathways for producing adipic acid, caprolactam, 6-aminohexanoic acid, 6-hydroxyhexanoic acid, hexamethylenediamine or 1,6-hexanediol by forming two terminal functional groups, comprised of carboxyl, amine or hydroxyl groups, in a C6 aliphatic backbone substrate. These pathways, metabolic engineering and cultivation strategies described herein rely on CoA-dependent elongation enzymes or analogues enzymes associated with the carbon storage pathways from polyhydroxyalkanoate accumulating bacteria.
US10533176B2 Cationic lipid
The present invention provides a compound represented by the formula (Ia) as a novel cationic lipid that forms a lipid particle and also provides a lipid particle comprising the compound. The present invention further provides a nucleic acid lipid particle containing the lipid particle, and a pharmaceutical composition containing the nucleic acid lipid particle as an active ingredient.
US10533175B2 Compositions and methods for modulating Ataxin 3 expression
Disclosed are methods for modulating splicing of Ataxin 3 mRNA in an animal with modified oligonucleotides. Such compounds and methods are useful to treat, prevent, or ameliorate spinocerebellar ataxia type 3 (SCA3) in an individual in need thereof.
US10533173B2 Precursor miRNA and applications in tumor therapy thereof
Provided are a new precursor miRNA and the applications in tumor therapy thereof. The precursor miRNA, from 5′- to 3′-end thereof, has the structure represented by formula (I). B1 is an anti-miRNA and/or siRNA to be expressed; B2 is a sequence substantially or completely complementary to B1, and B2 is not complementary to C; C is a sequence with stem-loop structure; A1 and A2 are independently hydrogen or optionally a RNA sequence consisting of 4 to 5 bases. The precursor miRNA can be processed to form an anti-miRNA and/or siRNA in hosts.
US10533164B2 Mutant sialidase having trans-sialidase activity for use in production of sialylated glycans
The invention provides a mutant enzyme having trans-sialidase activity (EC 3.2.1.18), characterized by an enhanced trans-sialidase:sialidase ratio when compared to its parent sialidase enzyme. Further the enzyme may be used in a method for trans-sialylating mono- and oligo-saccharides, including galacto-oligosaccharides (GOS), fructo-oligosaccharides (FOS), malto-oligosaccharides (MOS), isomalto-oligosaccarides (IMO), lactulose, melibiose, maltose, glycosyl sucrose, lactosucrose and fucose. Trans-sialidated mono- and oligo-saccharides, produced with the mutant enzyme, are useful in preparing infant formula, a prebiotic nutritional supplement, and a food supplement.
US10533163B2 Recombinant nucleoside-specific ribonuclease and method of producing and using same
A recombinant ribonuclease is disclosed. The recombinant ribonuclease is produced by introducing a recombinant DNA sequence into a host; activating expression of the recombinant DNA sequence within the host to produce the recombinant ribonuclease; and isolating the recombinant ribonuclease from the host. Additionally, a method of analyzing an RNA sequence includes digesting the RNA with a first recombinant ribonuclease to give digestion products comprising nucleotides of the RNA sequence; and analyzing the digestion products using an analytical method to provide the identity of at least some of the nucleotides. The recombinant ribonuclease includes at least one of a uridine-specific recombinant RNase MC1 and a cytidine-specific recombinant RNase Cusativin.
US10533160B2 Recombinant protein, and preparation method and application thereof
A recombinant protein and a preparation method and application thereof are provided. The recombinant protein includes a peptide, and the peptide includes an amino acid sequence after substitution of the sequence of SEQ ID NO: 1. The substitution includes at least one selected from the group consisting of the following substitutions: the amino acid at position 182 of SEQ ID NO: 1 is substituted with aspartic acid (Asp); the amino acid at position 268 of SEQ ID NO: 1 is substituted with aspartic acid (Asp); and the amino acid at position 384 of SEQ ID NO: 1 is substituted with tyrosine (Tyr). The recombinant protein is suitable for detecting glycated hemoglobin.
US10533159B2 Pichinde virus reverse genetics systems and methods of use
Provided herein are genetically engineered Pichinde viruses that include three ambisense genomic segments. The first genomic segment includes a coding region encoding a Z protein and a coding region encoding a L RdRp protein. The second genomic segment includes a coding region encoding a nucleoprotein (NP) and the third genomic segment includes a coding region encoding a glycoprotein. Each of the second and third genomic segments optionally include an additional coding region that may encode an antigen or a detectable marker. Also provided herein is a reverse genetics system for making a genetically engineered Pichinde virus, and a collection of vectors that can be used to produce a genetically engineered Pichinde virus. Further provided are methods for using a reverse genetics system, and methods for producing an immune response in a subject.
US10533157B1 Recombinant NK cells expressing co-stimulatory molecules
Cancer immunotherapy using genetically engineered NK cells is enhanced by expression of recombinant co-stimulatory molecules to deliver co-stimulatory signals to a recipient host's immune cells to enhance an immune response.
US10533155B2 Filamentous fungal biomats, methods of their production and methods of their use
A novel method of growing fungi is disclosed which uses an engineered artificial media and produces high density filamentous fungi biomats that can be harvested with a minimum of processing and from which fungal products such as antibiotics, proteins, and lipids can be isolated, the method resulting in lowered fungus cultivation costs for energy usage, oxygenation, water usage and waste stream production.
US10533152B1 Instruments, modules, and methods for improved detection of edited sequences in live cells
The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
US10533150B1 Electromagnetic biostimulation apparatus and method
An electromagnetic biostimulation apparatus and method includes a container with an outer wall, a bottom, and a top such that an open interior space is formed. Several biotubes are located within the container and an energy transmission device is provided where the energy transmission device is directed at less than all of the several biotubes. A laser beam and optical density reader device combination is provided where the optical density reader device obtains data from the laser beam related to each of the several biotubes.
US10533146B2 Cleaning formulations for removing residues on semiconductor substrates
This disclosure relates to a cleaning composition that contains 1) at least one redox agent; 2) at least one organic solvent selected from the group consisting of water soluble alcohols, water soluble ketones, water soluble esters, and water soluble ethers; 3) at least one metal-containing additive; and 4) water.
US10533142B2 Method and device for reducing heavy polycyclic aromatic compounds in hydrocracking units
The invention concerns a process and a facility for reducing the concentration of heavy polycyclic aromatic compounds (HPNA) in the recycle loop of hydrocracking units, which comprises a fractionation column. In accordance with this process, a portion of the stream present at the level of at least one plate (I) which is the supply plate or a plate located between the supply plate and the residue evacuation point, or if stripping gas is injected, between the supply plate and the stripping gas injection point, is withdrawn from the fractionation column. A portion, preferably all, of the withdrawn stream is recycled to the hydrocracking step directly or after optional separation of the gases. The residue is purged in its entirety.
US10533138B2 Recovery system for high pressure processing system
Products from a high pressure processing system are separated and purified. The processing system is adapted for pressurizing and heating a feed mixture comprising carbonaceous material(-s) in the presence of homogeneous catalysts and liquid organic compounds to produce a converted feed mixture. The converted feed mixture is cooled and depressurized, and then separated into: a gas phase, an oil phase, and a water phase comprising liquid organic compounds and dissolved homogeneous catalysts comprising potassium and/or sodium. The liquid organic compounds and dissolved homogenous catalysts are at least partly recovered from said water phase, thereby producing a first water phase stream enriched in liquid organic compounds and homogeneous catalysts and a second water phase stream depleted in liquid organic compounds and homogeneous catalysts. The first water phase is at least partly recycled to the feed mixture, with a bleed stream being withdrawn therefrom prior to recycling.
US10533135B2 Liquid crystalline medium
The present invention relates to a liquid-crystalline medium based on a mixture of polar compounds having negative dielectric anisotropy (Δε), which is distinguished by the fact that it has a value for the ratio γ1/Δn2 in the range 6-45 with a clearing point of >60° C. and a Δε of ≤−2.3. Media of this type are particularly suitable for electro-optical displays having active-matrix addressing based on the ECB, PA LCD, FFS or IPS effect.
US10533133B2 Rare earth spatial/spectral microparticle barcodes for labeling of objects and tissues
Polymer microparticles spatially and spectrally encoded using upconversion nanocrystals (UCN) are described for labeling of articles and tissues. UCN having spectrally distinguishable emission spectra are disposed in different portions of an encoding region of each microparticle.
US10533130B2 Charged particle radiation measuring method and charged particle radiation measuring device
Provided are a charged particle radiation measuring method and a charged particle radiation measuring device using a scintillator comprising a phosphor in which the main component is a SiAlON phosphor.
US10533129B2 Organic electroluminescent device
This invention relates to an OLED, comprising an anode, a cathode, and an organic layer, the organic layer at least contains one or more layers containing light emitting layer from the hole injection layer, hole transport layer, electron injection layer, electron transport layer, light emitting layer; the light emitting layer is composed of a single compound with the structure of formula (I). The OLED can emit blue light and has the advantages of high light emitting efficiency, excellent color purity and long lifetime.
US10533127B2 Compositions, quantum dot polymer composite and layered structure produced therefrom, and electronic device including the same
A composition including a plurality of metal oxide particles including a first stabilizer and a second stabilizer on a surface thereof; a plurality of quantum dots; a binder polymer including a carboxylic acid group; a polymerizable monomer including a carbon-carbon double bond; an initiator; optionally a multi-thiol compound comprising at least two thiol groups at one or more terminal ends thereof; and a solvent, wherein the first stabilizer and the second stabilizer are as provided herein.
US10533125B2 Thiol-ene based resin system for sand consolidation and methods using thereof
A method of treating a subterranean formation including combining a long chain hydrocarbon viscosifier, an ene curing agent, and a thiol crosslinking agent to form a resin compound; coating the resin compound onto at least a portion of proppant particles to create resin-coated proppant particles; and placing the coated proppant particles into the subterranean formation zone, wherein the resin compound does not substantially cure prior to placing the resin coated proppant particles into the subterranean formation zone.
US10533120B2 Compositions comprising a fluoroolefin
The present invention relates to compositions for use in refrigeration, air-conditioning, and heat pump systems wherein the composition comprises a fluoroolefin and at least one other component. The compositions of the present invention are useful in processes for producing cooling or heat, as heat transfer fluids, foam blowing agents, aerosol propellants, and fire suppression and fire extinguishing agents.
US10533117B2 Adhesives and related methods
Cure in place pressure sensitive adhesive compositions are described that comprise one or more of a bodying component, a structural diluent, a radical diluent as well as additives such as crosslinkers, external catalysts, photoinitiators and stabilizers/process aids. The bodying component can be acrylic or non-acrylic.
US10533116B2 Composite article
A composite article comprises a base layer and an adhesive layer disposed thereon. The base layer comprises the reaction product of a polyamide and an anhydride-functional copolymer, and an ionomer. The adhesive layer comprises a cationic polymer and an adhesive.
US10533112B2 Heavy-duty epoxy coating composition including styrenated phenol and method of preparing the same
A heavy-duty epoxy coating composition including an epoxy resin, as a main substance, and styrenated phenol represented by Formula 1: wherein n is an integer of 1 to 3.
US10533110B2 Coating composition, and super water-repellent film
A coating composition including the following five components 1) to 5): 1) a fluorine-containing multifunctional (meth)acrylate; 2) a binder component that is free of fluorine and reacts with the 1) component; 3) metal oxide nanoparticles each including an organic group on a surface thereof; 4) a solvent having a total (δP+δH) of 8 MPa1/2 or more, the total (δP+δH) being a total of a polar term δP and a hydrogen bond term δH in Hansen solubility parameters; and 5) a reaction initiator.
US10533106B2 Non-Newtonian white inks
The present disclosure provides an example where a non-Newtonian white ink can include an aqueous ink vehicle, from 5 wt % to 60 wt % of white colorant, and from 0.1 wt % to 5 wt % of amphoteric alumina particles dispersed in the aqueous ink vehicle. The white colorant can include white metal oxide pigment having an average particulate size from 100 nm to 2,000 nm, an alumina coating on the white metal oxide pigment forming an alumina-coated pigment, and a polymeric dispersant associated with a surface of the alumina-coated pigment. The amphoteric alumina particles can have an average particles size from 2 nm to less than 100 nm.
US10533104B2 Two-step process for forming cured polymeric films for electronic device encapsulation
Methods for increasing the degree of curing and/or reducing the volatile photoinitiator concentration in cured polymeric film, and particularly in cured polymeric films in a multilayered thin film encapsulation stack are provided. Also provided are highly crosslinked and/or low-outgassing thin polymeric films and encapsulation stacks made using the methods.
US10533101B2 Inorganic coating solution composition and method of forming inorganic coating film using the same
An inorganic coating solution composition including an alkali metal silicate, a curing agent, a dispersant, a defoamer, and a solvent, wherein the curing agent is phosphoric acid (H2PO4), the dispersant is at least one selected from among Tween 20, Tween 40, Tween 60, Tween 80, polyvinyl pyrrolidone, polyethylene glycol 400 and polyvinyl alcohol, and the defoamer is at least one selected from among a silicone-based defoamer, an alcohol-based defoamer, a mineral oil-based defoamer and a powder defoamer.
US10533095B2 Coating composition, method for making the coating and use thereof
A curable coating composition and the use, especially in heat exchangers, for heating and/or cooling water, in particular tap water, is described. The curable coating comprises, based on solids after curing, 35-80% by weight of an epoxysilane according to the general structure 1 and/or its hydrolysation and/or condensation products, 1: R1R2aSiR3b with R1 being 3-glycidyloxypropyl, R2 being methyl, R3 being alkyloxy or acyloxy, a being 0, 1 or 2 and b being 3−a and 20-65% by weight of a blocked polyisocyanate and optionally further components. The coating provides improved corrosion protection on aluminium surfaces, reduces limescale formation on heat exchanger surfaces and is able to withstand lateral and/or temporal temperature gradients when coated on heat exchanging surfaces.
US10533092B2 Water-soluble polymeric dyes
Water soluble polymeric dyes and polymeric tandem dyes are provided. The polymeric dyes include a water solvated light harvesting multichromophore having a conjugated segment of aryl or heteroaryl co-monomers including branched non-ionic water soluble groups (WSG) comprising two or more water soluble polymers. In some cases, the branched non-ionic water soluble groups (WSG) of the present disclosure are capable of imparting solubility in water in excess of 50 mg/mL to the multichromophore. The polymeric tandem dyes further include a signaling chromophore covalently linked to the multichromophore in energy-receiving proximity therewith. Also provided are aggregation-resistant labelled specific binding members that include the subject water soluble polymeric dyes. Methods of evaluating a sample for the presence of a target analyte and methods of labelling a target molecule in which the subject polymeric dyes find use are also provided. Systems and kits for practicing the subject methods are also provided.
US10533091B2 Color conversion with solid matrix films
This invention is directed to photoluminescent compounds based on rhodamine dyes with green or red emission and uses thereof for photoluminescence based devices.
US10533087B2 Vinyl chloride resin composition for powder molding and method for producing the same, vinyl chloride resin molded product and method for producing the same, and laminate
Provided is a vinyl chloride resin composition for powder molding that has excellent meltability in heat forming and high adhesiveness to a foamed polyurethane molded product after heat forming. The vinyl chloride resin composition for powder molding contains vinyl chloride resin particles (a), a plasticizer (b), a fatty acid amide (c), and vinyl chloride resin fine particles (d). The fatty acid amide (c) has a melting point of at least 105° C. and a content of at least 0.15 parts by mass and no greater than 13 parts by mass relative to a total content of 100 parts by mass of the vinyl chloride resin particles (a) and the vinyl chloride resin fine particles (d).
US10533083B2 Rubber composition and tire
An object of the present invention is to provide a rubber composition which is excellent in wet grip performance and abrasion resistance without deteriorating fuel efficiency, and a tire having a tread composed of the rubber composition. The present invention relates to a rubber composition comprising a rubber component comprising 20 to 90% by mass of a rubber component A and 10 to 80% by mass of a rubber component B, wherein an SP value of the rubber component A is not less than 17.8 (J/cm3)1/2 and an SP value of the rubber component B is lower than the SP value of the rubber component A by not less than 0.6 (J/cm3)1/2, and a tire having a tread composed of the rubber composition.
US10533082B2 Nitrile rubber glove with stretch modifier
An improved nitrile rubber formulation and process for making elastomeric nitrile rubber articles from the nitrile rubber formulation are disclosed. In particular, the nitrile rubber formulation can produce nitrile rubber based articles which exhibit force-strain characteristics that are comparable to those of natural rubber latex articles, while maintaining the tensile strength properties of nitrile rubber. The process includes adding a stretch modifier during the compounding of the nitrile rubber formulation. The invention also includes an elastomeric nitrile rubber product made by the process, such as examination glove, surgical glove, etc.
US10533078B2 Polymer film and method for preparing polymer film
The present invention relates to a polymer film comprising a base film comprising polyamide-based resin; and two or more kinds of copolymers comprising polyamide-based segments and polyether-based segments, and a method for preparing the polymer film.
US10533077B2 Method for bonding using adhesive layers with the aid of a laser
The invention relates to a method and a device for bonding two substrates, wherein an adhesive is applied to a first substrate and a second film-type substrate consisting of a thermoplastic material is converted into a plasticized state by heating before being bonded to the first substrate.
US10533072B2 Method of producing polyarylene sulfide
The production method of the present invention includes: a supplying step of supplying reaction raw materials to at least one of a plurality of reaction vessels that mutually communicate through a gas phase; a polymerizing step of carrying out a polymerization reaction; and a step of removing at least some of the water present in the reaction vessels. Each of the steps is carried out in parallel, and a reaction mixture is transferred sequentially between the reaction vessels. The amount of water contained in the reaction mixture in at least one of the reaction vessels is from 0.1 moles to less than 3 moles per mole of a sulfur source, and the total amount of water contained in the reaction raw materials that are supplied is 3 moles or more per mole of the sulfur source.
US10533069B2 Cyclic polysulfane-based polymer, method for preparing same, and film comprising same
The present disclosure relates to a cyclic polysulfane-based polymer, a cyclic polysulfane-polynorbornene block copolymer, a method of preparing the cyclic polysulfane-based polymer, a method of preparing the cyclic polysulfane-polynorbornene block copolymer, and a film including the cyclic polysulfane-polynorbornene block copolymer.
US10533066B2 Block copolymers that can be used as plasticisers
Disclosed is a block copolymer including: at least one block A not including any phosphonate group, and including at least one poly(alkylene oxide) group and at least one block B obtained by polymerization of a monomer B1 or of a mixture of monomers with ethylenic unsaturation including at least one monomer B1, wherein a monomer B1 is a monomer with ethylenic unsaturation including at least one phosphonate function, to its preparation method by RAFT controlled radical polymerization and to its uses.
US10533061B2 Grafting of cyclodextrin by amide bonds to an ether cross-linked hyaluronic acid and uses thereof
A hyaluronic acid product including a cross-linked hyaluronic acid and one or more cyclodextrin molecules. The hyaluronic acid is cross-linked by ether bonds, and the one or more cyclodextrin molecules are grafted onto the cross-linked hyaluronic acid by amide bonds, preferably using a triazine-based coupling reagent. A process of preparing a hyaluronic acid product including a cross-linked hyaluronic acid and one or more cyclodextrin molecules.
US10533056B2 Macropinocytosing human anti-CD46 antibodies and targeted cancer therapeutics
In various embodiments human anti-CD46 antibodies that are internalizing and enter tumor cells via the macropinocytosis pathway are provided, as well as antibody-drug conjugates (ADCs) developed from these antibodies for diagnostic and/or therapeutic targeting of CD46-overexpressing tumors.
US10533052B2 Antibodies against TIM3 and uses thereof
Provided herein are antibodies, or antigen-binding portions thereof, that bind to T-cell immunoglobulin and mucin-domain containing-3 (TIM3) protein. Also provided are uses of these antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of cancer. Further provided are cells that produce the antibodies, or antigen-binding portions thereof, polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof, and vectors comprising the polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof.
US10533049B2 Methods for reducing drug-induced liver injury
The present disclosure provides methods of treating a patient with infliximab or alternative therapies to reduce the risk of developing, and/or severity of, an adverse drug reaction such as drug-induced liver injury. The methods include identifying patients at risk for developing DILI by determining the presence or absence of one or more HLA alleles in the patients.
US10533044B2 Integrin Antagonists
Provided herein are integrin antagonists and methods of using the same. For example, one or more of the compounds or polypeptides provided herein can be used in the treatment of disorders such as heart attacks, stroke, and cancer metastasis. Also provided herein is a crystal comprising αvβ3 ectodomain complexed with inhibitor knottin 2.5 F. Further provided herein is a crystal comprising αVβ3 ectodomain complexed with inhibitor hFN10. In another aspect, the invention features a method that includes using a three-dimensional model of a complex that includes an integrin ectodomain.
US10533043B2 Single-chain glucocorticoid-induced tumor necrosis factor receptor (GITR) agonist proteins
Provided herein are specific GITR receptor agonist proteins, nucleic acids encoding the same, and methods of treating a subject having a GITRL-associated disease or disorder. The GITR receptor agonist proteins provided herein comprise three soluble GITRL domains and an Fc fragment. The GITR receptor agonist proteins are substantially non-aggregating and suitable for therapeutic, diagnostic and/or research applications.
US10533042B2 Peptides and compositions for treatment of joint damage
The present invention provides new protease resistant polypeptides, as well as compositions and methods for treating, ameliorating or preventing conditions related to joint damage, including acute joint injury and arthritis.
US10533039B2 Ras inhibitory peptides and uses thereof
The present invention provides peptides comprising a sequence of X−6X−5X−4X−3X−2X−1X1PX3X4PX6X7PGX10X11AX13X14X15X16LX18X19X20X21X22X23LX25X26 YLX29X30X31X32 (SEQ ID NO: 13) wherein the amino acids X−6, X−5, X−4, X−3, X−2, X−1, X1, X3, X4, X6, X7, X10, X11, X13, X14, X15, X16, X18, X19, X20, X21, X22, X25, X26, X29, X30, X31, and X32 are as defined herein. The present invention further provides pharmaceutical compositions comprising the peptides and methods of using the peptides for treating proliferative diseases such as cancer which are associated with Ras. Also provided are methods of screening a library of peptide dimers using a peptide dimer display technology.
US10533038B2 Methods of reducing TDP-43-mediated neuronal cytotoxicity in amyotrophic lateral sclerosis by a UPF1 polypeptide or polynucleotide
Nonsense-mediated mRNA decay (NMD) polypeptides, nucleic acids encoding NMD polypeptides, and methods of using such polypeptides and nucleic acids in the treatment of ALS and in screening for agents for the treatment of ALS are described.
US10533037B2 Freeze-dried powder of high molecular weight silk fibroin, preparation method therefor and use thereof
The invention discloses a freeze-dried powder of high molecular weight silk fibroin, preparation process and use thereof. The freeze-dried powder is obtained from silk by degumming, dissolution, dialysis, centrifugation, high temperature and high pressure treatment and freeze-drying. A method of preparing silk fibroin microspheres with polyethylene glycol comprises mixing a silk fibroin solution of 1-30 wt % with a PEG solution of 10-60 w % and incubating the resulting solution. A controlled-release or sustained-release silk fibroin gel formulation includes a gel-state carrier and a drug dispersed/adsorbed therein, the carrier is a silk fibroin gel formed by blending with LMW-PEG. The freeze-dried powder will not change the native molecular weight and random coil structure of silk fibroin, and can be rapidly dissolved into a solution, and can be stored and transported for a long time, and this reduces waste of silk fibroin materials and promotes R & D and biomedical applications of silk fibroin biomaterials.
US10533036B2 Clostridium difficile toxins a and/or B antigen and epitope antibody, and pharmaceutical uses thereof
It is described a Clostridium difficile (C-difficile) toxins A and/or B as a target for therapy, including passive immunotherapy, and particularly prevention of C-difficile intoxication in human or other animals. It is also described a polypeptide comprising a portion of C-difficile toxins A and/or B sequence being an epitope for anti-toxins A and/or B antibody. It is also disclosed a method for generating a neutralizing antibody directed against C-difficile toxins A and/or B. It is also provided a novel formulation that combines key toxins A and/or B epitope antibodies, located in three key domains of toxins A and/or B, for neutralizing toxins A and/or B, at any stage of toxins A and/or B intoxication related to C-difficile infection. The novel formulation of toxins A and/or B epitope antibodies are useful in immunotherapy, for therapeutic and/or prophylactic mediation of C-difficile intoxication.
US10533035B2 C-3 novel triterpenone with C-17 reverse amide derivatives as HIV inhibitors
The invention relates to C-3 novel triterpenone with C-17 reverse amide derivatives, related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated diseases.
US10533034B2 Human iNKT cell activation using glycolipids
Glycosphingolipids (GSLs) compositions and methods for iNKT-independent induction of chemokines are disclosed.
US10533033B2 Lipid A mimics, methods of preparation, and uses thereof
The invention provides lipid A mimics in which one or both of the sugar residues of a natural lipid A disaccharide backbone has been replaced with an aromatic group. These lipid A mimics may further differ from a natural lipid A molecule with respect to other structural characteristics, such as, a different number of phosphate groups present, changes in the number, structure and location of lipid chains and/or changes in the spacing and linkage of the sugar residues (or their aromatic replacements). The lipid A mimics may be lipid A agonists and as such may be useful as immunostimulatory agents in inducing or patenting an antibody and/or cell-mediated immune response, or may be lipid A antagonists and as such may be useful in treating or preventing a lipopolysaccharide (LPS)/lipid A-mediated disease or disorder. Also provided are methods for preparing the lipid A mimics.
US10533031B2 Methods of making and using lignin derivatives
Materials and methods for preparing reactive lignin and for preparing a bio-based adhesive are described herein.
US10533024B2 Methods for synthesizing metal mesoporphyrins
Embodiments describe methods of synthesizing metal mesoporphyrin compounds. In embodiments, a metal mesoporphyrin compound may be formed by hemin transmetallation and subsequent hydrogenation of the tin protoporphyrin IX to form a metal mesoporphyrin. In other embodiments, a method of synthesizing a metal mesoporphyrin compound comprises forming a protoporphyrin methyl ester from hemin and converting the protoporphyrin methyl ester intermediate to a metal mesoporphyrin compound through metal insertion and hydrogenation. In other embodiments, a metal mesoporphyrin compound may be formed from hemin by a hydrogen-free hydrogenation method to form a mesoporphyrin IX intermediate followed by metal insertion and hydrogenation. In embodiments, a method of synthesizing a metal mesoporphyrin compound comprises forming a mesoporphyrin IX dihydrochloride intermediate compound and converting the mesoporphyrin IX intermediate to a metal mesoporphyrin compound through metal insertion. In embodiments, a metal mesoporphyrin compound may be formed directly from hemin without isolation of any intermediates.
US10533021B2 Boron-containing small molecules
This invention provides, among other things, novel compounds useful for treating bacterial infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
US10533018B2 Antimicrobial prochelators to target drug-resistant bacteria and methods of making and using the same
The present disclosure provides antibacterial prodrugs and methods of making and using the same.
US10533015B1 Opioid receptor antagonist prodrugs
Provided herein are prodrugs of opioid receptor antagonists such as nalmefene and naltrexone, pharmaceutical compositions comprising said compounds, and methods for using said compounds for the treatment of behavioral disorders.
US10533013B2 Substituted pyrazolo[3,4-d]pyrimidines as kinase inhibitors
The present disclosure provides compounds of Formula (IA), such as, e.g., (R)-2-(3-(4-amino-3-(2-fluoro-4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carbonyl)-4-methyl-4-(4-(oxetan-3-yl)piperazin-1-yl)pent-2-enenitrile having the chemical structure  and/or pharmaceutically acceptable salts thereof that are tyrosine kinase inhibitors, in particular BTK inhibitors, and are potentially useful for the treatment of diseases treatable by inhibition of tyrosine kinases such as cancer, inflammatory diseases such as arthritis, and the like. Also provided are pharmaceutical compositions containing such compounds and/or pharmaceutically acceptable salts thereof and processes for preparing such compounds and pharmaceutically acceptable salts thereof.
US10533010B2 Substituted indole Mcl-1 inhibitors
The present invention provides for compounds that inhibit the activity of an anti-apoptotic Bcl-2 family member Myeloid cell leukemia-1 (Mcl-1) protein. The present invention also provides for pharmaceutical compositions as well as methods for using compounds for treatment of diseases and conditions (e.g., cancer) characterized by the over-expression or dysregulation of Mcl-1 protein.
US10532996B2 Proteostasis regulators
The present invention is directed to compounds having the Formulae (Ia-Ie), (II), (IIIa-IIId), (IVa-IVc), (Va-Vb), (VIa-VIe), (VII), (VIIIa-VIIIc), and (IX), pharmaceutically acceptable salts, prodrugs and solvates thereof, compositions of any of thereof and methods for the treatment of a condition associated with a dysfunction in proteostasis comprising an effective amount of these compounds.
US10532995B2 Substituted pyrazole compounds as serine protease inhibitors
There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of thrombin and/or kallikrein, which compounds include substituted pyrazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which diseases or disorders are amenable to treatment or prevention by the inhibition of thrombin and/or kallikrein.
US10532993B2 Beta- and gamma-amino-isoquinoline amide compounds and substituted benzamide compounds
Disclosed are beta and gamma-amino isoquinoline amide compounds and substituted benzamide compounds. In particular, the invention provides compounds that affect the function of kinases in a cell and that are useful as therapeutic agents or with therapeutic agents. The compounds of the invention are useful in the treatment of a variety of diseases and conditions including eye diseases such as glaucoma, cardiovascular diseases, and diseases characterized by abnormal growth, such as cancers. The invention further provides compositions containing the beta or gamma-amino isoquinoline amide compounds or substituted benzamide compounds.
US10532990B2 Methods for converting cellulose to furanic products
The present invention relates to systems, methods, and processes for the production of conversion products such as furanic products from biomass such as lignocellulosic materials.
US10532987B2 Compounds and methods for inducing browning of white adipose tissue
The present invention provides a compound for inducing browning of white adipose tissue in vitro and in vivo of formula I, the preparation method thereof, as well as a composition comprising the same. Further, the present invention also relates to the use of the compound and the method to treat metabolic disorders, such as obesity and diabetes.
US10532986B2 Cyclic compound acting as PDE4 inhibitor
Provided are a phosphodiesterase-4 (PDE4) inhibitor and application thereof in preparation of a medication for treating a disease related to PDE4. Specifically disclosed is a compound as shown in formula (I) and a pharmaceutically acceptable salt thereof.
US10532985B2 Heterocycle and carbocycle derivatives having TRKA inhibitory activity
The present invention relates to a compound represented by Formula (I): wherein -L- is —C(═X)—, or the like, —Z— is —NR5—, or the like, —ZA— is —NR5A—, or the like, —W— is —C(R8R9)n-, —WA— is —C(R3R4)m-, B is substituted or unsubstituted aromatic carbocyclyl, or the like, Y is a bond, or the like, the ring C is a substituted or unsubstituted aromatic heterocycle, or the like, R2 is a hydrogen atom, or the like, or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising thereof.
US10532977B2 Small molecule inhibitors of protein tyrosine phosphatases and uses thereof
Small molecule compounds derived from α-sulfophenylacetic amide (SPAA) are provided as novel sulfonic acid based pTyr mimetics. These compounds effectively inhibit a variety of protein tyrosine phosphatases (PTPs), such as mPTPA, mPTPB, LMWPTP, and Laforin. Use of these compounds as pharmaceutical agents for treating diseases associated with abnormal protein tyrosine phosphatase activity is also provided.
US10532976B2 FTO inhibitors
The invention provides compounds that inhibit FTO (fat mass and obesity), including pharmaceutically acceptable salts, hydrides and stereoisomers thereof. The compounds are employed in pharmaceutical compositions, and methods of making and use, including treating a person in need thereof, particularly obesity, with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition.
US10532975B2 Cationic lipids for therapeutic agent delivery formulations
Here described is a method of delivery of a drug to a stellate cell using a composition comprising a compound of formula I: wherein R1 and R2 are independently selected from C10 to C18 alkyl, C12 to C18 alkenyl, and oleoyl; R3 and R4 are independently selected from C1 to C6 alkyl and C2 to C6 alkanol; X is selected from —CH2—, —S—, and —O—, or X is absent; Y is selected from —(CH2)n, —S(CH2)n—, —O(CH2)n—, -thiophene-, —SO2(CH2)n—, and ester; n═1-4; a═1-4; b═1-4; c═1-4; and Z− is a counterion.
US10532973B2 Acetylsalicylic acid derivative crystal, its preparation method and use
Disclosed are an acetylsalicylic acid derivative, i.e. a 2-(diethylamino)ethyl 2-acetoxy-benzoate hydrochloride crystal, and a preparation method and use thereof. The X-ray powder diffraction (XRPD) pattern of the crystal has characteristic peaks at the following 2θ angle: 11.0°±0.2°, 20.6°±0.2°, 25.1°±0.2°, 8.2°±0.2°, 16.5°±0.2°, 13.4°±0.2°, 25.4°±0.2°.
US10532972B2 Dibasic esters and the use thereof in plasticizer compositions
Dibasic esters (diesters) and their use in plasticizer compositions are generally disclosed. In some embodiments, the diesters are branched-chain esters of long-chain alkanedioic acids, such as octadecanedioic acid. In some embodiments, such plasticizer compositions are used to increase the plasticity of a polymer resin, such as a vinyl chloride resin or poly vinyl butyral. In some other embodiments, such plasticizer compositions are used to lower the glass transition temperature of a polymer resin. In some embodiments, at least a portion of the plasticizer is derived from a renewable source, such as a natural oil.
US10532968B2 Method for purifying phenol
The present invention relates to a method for purifying phenol, which comprises: supplying a feed comprising phenol, acetone, hydroxyacetone and water to a distillation column at 60° C. to 95° C.; separating the feed into a first fraction, which comprises the acetone, and separates to the upper part of the distillation column and a second fraction, which comprises the phenol, and separates to the lower part of the distillation column; and recovering the first fraction and the second fraction, respectively.
US10532963B2 Methods for the oxidative dehydrogenation of butene to produce butadiene
Methods for producing butadiene by the oxidative dehydrogenation of butene are provided. Methods for producing butadiene from a feed stream including oxygen and butene in a molar ratio of oxygen to butene (O2/C4H8) from about 0.9 to about 1.5 can include introducing the feed stream to a catalyst in the presence of steam. The molar ratio of steam to butene (H2O/C4H8) can be from about 10 to about 20. Methods can further include reacting the butene to generate a product stream therefrom comprising butadiene and water. Methods can further include separating water from the product stream to generate a butadiene stream including greater than about 85 wt-% butadiene.
US10532961B2 Catalyst and method of preparing light olefin directly from synthesis gas by one-step process
The present invention discloses catalyst and method for producing light olefins directly from synthesis gas by a one-step process, and particularly relates to method and catalyst for directly converting synthesis gas into light olefins by a one-step process. The provided catalysts are composite materials formed of multicomponent metal oxide composites and inorganic solid acids with hierarchical pore structures. The inorganic solid acids have a hierarchical pore structure having micropores, mesopores and macropores. The metal composites can be mixed with or dispersed on surfaces or in pore channels of the inorganic solid acid and can catalyze the synthesis gas conversion to a C2-C4 light hydrocarbon product containing two to four carbon atoms. The single pass conversion of CO is 10%-60%. The selectivity of light hydrocarbon in all hydrocarbon products can be up to 60%-95%, wherein the selectivity of light olefins (C2═—C4═) is 50%-85%.
US10532960B1 Non-energetic resin-based olive smoke fill
A non-energetic smoke fill composition including a resin, a curing agent, a metallic filler, and a non-metallic filler, wherein the smoke fill composition is configured to be inserted into any of an artillery shell, a mortar cartridge, a gun cartridge, and in general an ogive of a projectile, and wherein the smoke fill composition is configured to be disseminated by a fuze and a supplemental charge to produce a signal visible in both day or night conditions.
US10532954B2 System, method and apparatus for entraining air in concrete
A method of preparing a concrete composition for downhole injection includes utilizing a controller to control a process including circulating process water in a process water supply loop for a predetermined period while monitoring and controlling the temperature and flow rate of the process water, circulating aqueous-based air entrainment solution in an aqueous-based air entrainment solution supply loop for the predetermined period and controlling the flow rate of the aqueous-based air entrainment solution and after the predetermined period of time in which the flow of process water and aqueous-based air entrainment solution have stabilized, simultaneously actuating valves to divert and mix the process water, the aqueous-based air entrainment solution and compressed air to produce an air-entrained foam and mixing the foam with a concrete composition to be deployed downhole.
US10532953B2 Precursor material for additive manufacturing of low-density, high-porosity ceramic parts and methods of producing the same
A precursor material is provided for additive manufacturing of a low-density, high-porosity ceramic part. The precursor material includes a body of refractory fibers and a binder in admixture with the body of refractory fibers. The precursor material further includes a viscosity control additive in admixture with the binder and the body of refractory fibers to provide an overall mixture with a viscosity between about 0.3 centipoise and about 150,000 centipoise.
US10532952B2 Method including sonication and spark plasma sintering for forming a ceramic material
A method for producing a composite of cubic boron nitride dispersed in a SiAlON ceramic. This method involves mixing silicon nitride nanoparticles, aluminum nitride nanoparticles, silica nanoparticles, calcium oxide nanoparticles, and cubic boron nitride microparticles to produce a mixture. The cubic boron nitride may be coated with nickel. The mixture is sintered to produce the composite, and this sintering may involve spark plasma sintering and/or sintering at a relatively low temperature. The composite may comprise a mixture of Ca-α-SiAlON and β-SiAlON ceramic reinforced by boron nitride in either or both cubic and hexagonal phases.
US10532950B2 Cubic boron nitride sintered body and coated cubic boron nitride sintered body
A cubic boron nitride sintered body has between 50% and 75% cubic boron nitride by volume and between 25% and 50% binder phase by volume, and inevitable impurities. The binder phase contains an Al compound and a Zr compound. The Al compound contains Al and one or more of N, O and B; and the Zr compound contains Zr and one or more of C, N, O and B. At a polished surface of the cubic boron nitride sintered body, 40% or more of the Zr compounds satisfy the ratio 0.25≤n/N≤0.8, where: N represents the number of line segments drawn radially at equal intervals from a center of gravity of a given Zr compound to a boundary with a non-Zr compound; and n represents the number among those N line segments which intersect a boundary between the given Zr compound and cubic boron nitride.
US10532946B2 Composite element and use thereof
A lightweight composite pane is provided that includes a mineral glass or glass-ceramic pane and an organic layer. The weight per unit area of the lightweight composite pane is in the range from 0.5 kg/m2 to 5.5 kg/m2, the ratio of the thickness of the mineral glass pane to the thickness of the organic layer is 1:0.01 to 1:1, and the thickness of the organic layer is less than or equal to 500 μm. The lightweight composite pane meets the thermal safety requirements of aerospace authorities and has a “Total Heat Release,” measured in compliance with JAR/FAR/CS 25, App. F, Part IV & AITM 2.0006, of less than 65 kW×min/m2 and a flame time, after removal of the flame in the “Vertical Bunsen Burner Test”, measured in compliance with FAR/JAR/CS 25, App. F, Part 1 & AITM 2.0002A, is less than 15 seconds.
US10532940B2 Aeration discs and methods for using same
Aeration discs used in water treatment and methods of using same are disclosed. According to one or more embodiments, an aeration disc may comprise projections and depressions located on at least one of its surfaces. The aeration discs may be incorporated into aeration devices and water treatment systems.
US10532935B2 Water harvester and purification system and method of making and using same
A system for producing potable water, including a primary water harvester including a non-potable water source, gas heating chamber, wherein the gas heating chamber includes a gas directing tube having a gas located within the gas directing tube such that the gas heating chamber is used to heat the gas located within the gas directing tube, a gas mover operatively connected to the gas directing tube for moving the heated gas contained within the gas directing tube, an evaporator operatively connected at one end to the gas directing tube, wherein the heated gas located within the gas directing tube contacts non-potable from the non-potable water source such that a water vapor in the heated gas is increased, and a condenser operatively connected to the other end of the evaporator, wherein the condenser causes the water vapor to condense out of the heated gas to produce potable water. A secondary function of the system allows it to act as a concentrator for organic and inorganic components present in the non-potable water that can be considered additional resources to be recovered in addition to the potable water produced by the system.
US10532931B2 Method for carbonizing lignocelluosic material as a powder
The present invention provides a novel cost efficient method for carbonizing lignocellulosic material to carbonized particles or agglomerates, preferably carbon powder. Also uses of said particles or agglomerates are disclosed.
US10532930B2 Method for production of sulfuric acid from sulfur containing feeds with gas quenching
A plant for the production of sulfur trioxide from a feed stream containing sulfur-containing compounds and dissolved metals and alkali metals by a process, which involves gas quenching, comprises an incineration furnace, a mixing device and/or a dilution air heater, a dust removal device and an SO2 converter. The plant may further comprise a condenser for the purpose of producing sulfuric acid.
US10532929B2 Energy efficient sulfuric acid system for humid environments
A contact process, sulfuric acid system and method are disclosed for producing sulphuric acid with improved operating efficiency in humid environments. The system comprises a pre-drying absorber for pre-drying humid air with weak sulfuric acid. Weak sulfuric acid from the pre-drying absorber is provided to a subsystem comprising two sulfur trioxide absorbers and a heat exchanger for the recovery of heat via steam production. This arrangement allows for a marked increase in steam production (i.e. energy efficiency). In a separate improvement, the emission apparatus for the system can be simplified using a peroxide tail gas scrubber comprising upper and lower scrubber sections in which the upper scrubber section consists essentially of tray type scrubbers.
US10532922B2 Micro-electro-mechanical actuator device of piezoelectric type and apparatus integrating the micro-electro-mechanical actuator device
A micro-electro-mechanical actuator device includes a fixed structure and a mobile structure. The mobile structure includes a first deformable band, a second deformable band, and a third deformable band, both of which extend on opposite sides of the first deformable band, each of which carries a piezoelectric actuator. In a working condition, in which the second and third piezoelectrics are biased, the second and third deformable bands are subjected to a negative bending, while the first deformable band is subjected to a positive bending. There are thus generated two translations that add together, causing a displacement of the first deformable band greater than the one that may be obtained by a single membrane of an equal base area.
US10532920B2 Soap, sanitizer and lotion refill units management and tracking
An exemplary methodology for managing soap, sanitizer and lotion refills includes associating a first refill unit with a first dispenser, determining one or more usage rates for the first dispenser, determining an expected depletion date for the first refill unit. The methodology further includes associating a second refill unit with a second dispenser, determining one or more usage rates for the second dispenser, and determining an expected depletion date for the second refill unit. The methodology further includes providing instructions to move the first refill unit to the second dispenser and the second refill unit to the first dispenser.
US10532919B2 Collapsible personnel basket for a crane
A collapsible personnel basket apparatus quickly and easily deploys on the tip of a crane boom and stores in a space-efficient manner when not in use. The basket apparatus has a collapsible spine made up of a plurality of spine segments, a support platform pivotally coupled to a bottom spine segment, a connection member pivotally coupled to a top spine segment and including a coupling portion at a proximal end thereof, an adapter configured for attachment to a crane tip at a distal end of a crane boom, and a foldable rail assembly removably mountable on the spine and/or the support platform. The adapter mates with the coupling portion of the connection member to removably mount the connection member on the crane tip. A related deployment method, spine segment locking mechanism, coupling apparatus, and storage apparatus are also disclosed.
US10532914B2 Hooking device for lifting loads comprising a secure ratchet
A device for lifting and transporting a load attached by a sling includes a hook comprising a throat opening intended to receive a loop on a sling. The device includes a latch that can pivot between an open position and a closed position in which said throat opening is obstructed. The device includes a locking device including a locked position in which said locking device prevents the latch from turning in the closed position, and an unlocked position in which the latch can rotate; a lever including a loaded position in which said lever holds the locking device in the locked position and a released position in which said lever does not hold said locking device. A rotation of the latch from the closed position to the open position triggers the lever from the loaded position to the released position.
US10532913B1 Sprockets for people conveyors
People conveyors and components for people conveyors are described. The components include a toothed surface having at least one tooth. The at least one tooth having an engagement surface and a surface pattern comprising pattern channels formed into the engagement surface.
US10532912B2 Rotating electrical machine, hoisting machine and elevator
According to one embodiment, a rotating electrical machine includes an annular winding, a stator core, and a rotor core. At least one of the stator core and the rotor core includes a first member and a second member. The first member and the second member are formed in annular shape. The first member and the second member overlap each other in an axial direction of the shaft. The first member includes a slit-shaped first insulation section. The first insulation section extends in the axial direction. The second member includes a slit-shaped second insulation section. The second insulation section extends in the axial direction. The first member and the second member are integrally connected. The first insulation section and the second insulation section are disposed at different positions in the rotation direction.
US10532911B2 Motor drive having dual inverter system connected to first and second stator sections
A linear propulsion system and method of assembling and testing the same. The linear propulsion system may comprise a track, a vehicle, a mover mounted to the vehicle, and a dual inverter system. The track may include a first plurality of stator sections interleaved with a second plurality of stator sections. The dual inverter system may include first and second multi-phase inverters (52a, 52b) that share input hardware.
US10532909B2 Elevator passenger tracking control and call cancellation system
A passenger conveyance passenger tracking control system that controls operation of a passenger conveyance, e.g., an elevator car, includes at least one call request device, e.g., a call request panel, configured to receive at least one input from at least one passenger located at a occupancy depth grid. At least one passenger position three-dimensional (3-D) depth-sensing sensor is configured to track a position of the at least one passenger located at the occupancy depth grid. The passenger conveyance passenger tracking control system further includes an electronic control module in signal communication with the at least one call request device and at least one passenger position 3-D depth-sensing sensor. The electronic control module is configured to control operation of the passenger conveyance based on the position of the at least one passenger.
US10532907B2 Adhesive tape cartridge, adhesive tape roll, and manufacturing method of adhesive tape roll
An adhesive tape cartridge can include an adhesive tape roll that winds a double-faced adhesive tape. The double-faced adhesive tape includes a base material layer, a first adhesive layer, a second adhesive layer, a third adhesive layer, and a separation material layer. The first adhesive layer is disposed on one side of the base material layer and includes an adhesive with a first pigment added. The second adhesive layer is disposed on the one side of the first adhesive layer and includes an adhesive with a second pigment added. The third adhesive layer is disposed on the other side of the base material layer. The separation material layer is disposed on the other side of the third adhesive layer. A volume ratio of the first pigment in the first adhesive layer is greater than a volume ratio of the second pigment in the second adhesive layer.
US10532905B2 Sheet conveyance apparatus and image forming apparatus
A sheet conveyance apparatus includes a body portion, and an openable unit including an openable portion supported by the body portion, a first movable guide to guide a sheet, a supporting portion to movably support the first movable guide between a first position, at which a first conveyance path through which the sheet is conveyed is formed between the first movable guide and the openable portion, and a second position, at which the first conveyance path is opened, the supporting portion being moved away from the body portion along with an opening operation of the openable portion, and a second movable guide movably supported by the first movable guide. An abutment portion abuts with the second movable guide in a state where the openable portion is closed, such that the second movable guide is held on a position to form a second conveyance path through which the sheet is conveyed.
US10532903B2 Winding device for web-shaped material and method for drawing at least one material web into at least one winding device
A winding device for a web-shaped material has at least one first frame and at least one first roller holding device, with at least one roller holding assembly which can rotate about a first rotational axis. The winding has device at least one pressing element, and the at least one pressing element is arranged to be movable relative to the first frame in at least one adjustment direction and opposite that at least one adjustment direction. The at least one adjustment direction has at least one component which points towards the first rotational axis. A guide system for at least one drawing device, for drawing at least one material web, is arranged such that a first guide section of the guide system is arranged in a stationary manner relative to the at least one first frame. At least one linear connection between the at least one pressing element and the first rotational axis always intersects a second guide section of the guide system, regardless of the position of the at least one pressing element. A method for drawing a material web into a winding device is also provided.
US10532897B2 Hydraulic hoisting system and method
Disclosed is a hydraulic hoisting system for moving material from an underground position to a surface level. In most cases, the system will be used to move fragmented rock or ore generated during the normal operation of a mine to a position on or near the surface of the Earth so that the rock or ore can be further processed. The system is a conduit loop for continuous flow of circulating fluid from near or at the surface to underground; a slurry preparation unit for mixing the material with a portion of the fluid to form a slurry; and an injection unit for injecting the slurry into the conduit.
US10532892B2 Transport device for the row-by-row relocation of piece goods that are prone to falling over
A relocation method for moving piece goods and an associated transport device are provided. The piece goods (2), that are prone to falling over, in particular bottles, are moved between an in-flow region (E) and a holding area (9) for a layer (10) formed of adjacent rows (3, 4, 5) of the piece goods (2). A transport device (1) has multiple relocation guides (11-15) which are moveable in a controlled manner, and which are configured to transport a row (3-7) or a set of rows of the piece goods between the inflow region (E) and the holding area, to assemble or disassemble a layer. A respective second-outermost row (K2) or a second-outermost set of rows of the layer are secured against falling over by means of a relocation guide (11). An outermost row (K1) or an outermost set of rows is added to the layer or removed from the layer.
US10532890B2 Vibratory apparatus with structural resilient member
A vibratory apparatus includes a first mass comprising a first deck with a path of travel between a first point and a second point along the first deck, a second mass comprising a second deck with a path of travel between a first point and a second point along the second deck, a shaft coupled to the first mass and at least one eccentric weight coupled to the shaft, and at least one resilient member in the form of a plate having a thickness, the plate coupled at a first end to the first deck and at a second end to the second deck, the plate having a thickness disposed transverse to the path of travel along the first and second decks, the plate having at least one opening formed therethrough to form a web having a spring characteristic.
US10532886B2 Apparatuses and methods for producing containers
The apparatus includes an operating unit, which can be a welding unit for welding a closing film to an edge zone of a containing element or a separating unit for separating containing elements from portions of sheet material. The apparatus includes a control unit programmed to enable the operating unit to selectively process a continuous strip of containing elements or discrete groups of containing elements.
US10532884B2 Mechanical end effector for planar motion mechanism
The invention is a planar motion mechanism with a mechanical end effector. The mechanism has a vertical slide table that moves along one or more vertical tracks. The vertical slide table includes one or more horizontal tracks, an arcuate guide rail parallel to the horizontal tracks, and a horizontal slide table that moves along the horizontal tracks. The horizontal slide table comprises an end effector, which is a suspended perpendicular arm with a lip on the bottom edge that supports a load. The end effector, when unloaded, follows the path of the arcuate guide rail as the horizontal slide table moves along the one or more horizontal tracks. In this way, the end effector engages the load in positions near the edge of the arcuate guide rail, but in central positions along the arcuate guide rail, the end effector is distanced from the load so that it can freely maneuver.
US10532883B2 Trash can with customizable features
Described is a system for controlling the operation of a trash can lid that includes a shell for receiving trash, a lid assembly that covers a portion of the shell, and an actuator assembly that independently controls the rate in which the lid assembly moves with respect to the shell. Also provided is a system for improving the operation of a trash can that includes a lid assembly for covering a portion of a shell, an actuator assembly, a base assembly, and a hydraulic component. The hydraulic component controls the rate in which a portion of the lid assembly moves with respect to the shell. The system further includes an adjustable volume of space that is formed between the base assembly and the removable liner when the removable liner is coupled to the base assembly. The adjustable volume of space can be used to store deodorizers, insecticides, or the like.
US10532882B2 Shipping and dispensing box for slit sheet material
Exemplary embodiments pertain to a combined shipping and expansion device for shipping a roll of unexpanded slit sheet material and for expanding the slit sheet material. In some examples, the device includes: a container made with recyclable paper or board; a roll of slit sheet material wound around a core member and positioned within the container; the roll of slit sheet material having a slit pattern that forms open cells upon expansion; the core member being made with recyclable paper or board and having a length greater than a width of the roll of slit sheet wound around the core member and having protrusions that extend beyond each side of the roll of slit sheet material; a plurality of yoke members within the container, including at least one yoke member that rotatably receives a first of the protrusions and at least one yoke member that rotatably receives a second of the protrusions; and the container having a dispensing opening through which the slit sheet material wound around the core member can be extended and pulled, causing the core member to rotate relative to the yoke members via rotation of the roll of slit sheet material. The combined shipping and expansion device is made from substantially entirely recyclable paper or board materials, whereby after complete dispensing of the slit sheet material from the shipping and expansion device, the combined shipping and expansion device can be recycled in a paper recycling facility.
US10532881B2 Process for manufacturing an aerosol valve and aerosol valve
A cup/valve assembly for an aerosol container, made up of a cup, a valve body, a stem, a spring, and an inner seal. The stem comprises a bulge on its outer cylindrical face and an inner conduit which has an upper opening at its upper end and at least one lateral orifice at its lower end between the bulge and the upper opening of the inner conduit. The valve body has an opening at its upper end. The valve body is fixed to a central opening (23) of the cup leaving the opening in the cylindrical portion free, and the stem is retained in the valve body by a retaining ring (5) that surrounds, without tightening, the stem, and is fixed to the cup, the inner seal (13) being interposed between the retaining ring (5) and the top edge of the cylindrical portion of the valve body.
US10532870B2 Device for conveying a bag comprising a biopharmaceutical fluid and systems and a method using same
Disclosed is a device for transporting a biopharmaceutical fluid, including an inner bag forming an inner chamber adapted and intended for receiving a biopharmaceutical fluid, an outer container including an outer receptacle, the outer receptacle including a wall forming an outer chamber, an expandable protective element arranged at least partially between the outer receptacle and the inner bag and adapted to receive the inner bag, the expandable protective element being adapted to expand in volume to an expanded state so as to be interposed between the outer receptacle and the inner bag, the expandable protective element in the expanded state surrounding the inner bag and filling the space between the wall of the outer receptacle and the inner bag.
US10532868B2 Tag assembly for retaining and displaying products
A tag assembly (10, 210, 310, 410) includes a tag panel (14, 314, 414) and a elastomer panel (16). The tag panel (14, 314, 414) includes a first panel segment (22a, 322a, 422a) and a second panel segment (22b, 322b, 422b) demarcated from the first panel segment (22a, 322a, 422a) by a first fold line (48a, 348a). The second panel segment (22b, 322b, 422b) includes a panel aperture (34) and a plurality of slits (36, 236) communicating with the panel aperture (34) and defining a plurality of tabs (38, 238) therebetween. A retention aperture (24, 52, 58) is positioned on and through the tag panel (14, 314, 414). The elastomer panel (16) is bonded to the second panel segment (22b 322b 422b) and comprises a stretchable aperture (44), wherein the stretchable aperture (44) overlaps the panel aperture (34). A method for displaying a product (12) includes providing a tag assembly (10, 210, 310, 410), inserting a first portion (12a) of the product (12) through the stretchable aperture (44), inserting the first portion (12a) of the product (12) through the panel aperture (34), and restricting the first portion (12a) from withdrawing through the panel aperture (34) with the radially-separated tabs (38, 238) of the tag panel (14, 314, 414).
US10532867B2 Gift card presentation devices
The disclosed invention relates generally to various embodiments of holders and packaging for giving gifts. In particular, the invention relates to various gift card holders that hold a gift card and enhance the presentation and gift giving experience for recipients and gift givers alike. The holders and packing also permit a gift card disposed therein to be visible, scanned, accessed, or otherwise activated without removing the gift card from the holder.
US10532865B2 Presentation box for a transaction card
A presentation box for presenting a transaction card may include a hinged lid connected to a hinge edge of the presentation box, the hinged lid to pivot about the hinge edge of the presentation box when moved between a closed position and an open position; and/or a presentation apparatus that may include a tether that may be attached to the hinged lid, and/or a sleeve to receive the transaction card, where the presentation apparatus is to move the transaction card between a first position when the hinged lid is in the closed position and a second position when the hinged lid is in the open position, where the first position is different from the second position.
US10532860B2 Container that prevents an illegal operation and can be easily identified after being illegally operated
A container that prevents illegal operation and can be easily identified after being illegally operated, includes a bowl-shaped base and a cover selectively closing the bowl-shaped base, wherein a pre-broken structure is formed on the cover and the cover cannot be smoothly detached from the bowl-shaped base before the pre-broken structure being damaged. For the market, the salesperson easily confirms that the container has been illegally operated and the illegally operated container is replaced in time for providing fresh goods to the consumers. For consumers, the illegally operated containers can be easily confirmed and eliminated through choosing for preventing from buying unsafe or stale goods, particularly foods.
US10532850B2 Folding box
A folding box (100), comprising: a bottom plate (1), and a pair of first side plates (2) and a pair of a second side plates (3) capable of being folded with respect to the bottom plate (1). The first side plates (2) and the second side plates (3) are releasably interlocked via a locking mechanism (4). The locking mechanism (4) comprises a handle (41), a locking member (42), and a guidance feature (31). When the first side plates (2) and the second side plates (3) are in a locked state, the handle (41) restricts the position of the locking member (42), thus limiting the movement of the locking member (42), when the handle (41) restricts the position of the locking member (42), thus limiting the movement of the locking member (42), when the handle (41) moves and provides the locking member (42) space required for movement of the locking member (42), the locking member (42) cooperates with the guidance feature (31) to drive the locking member (42) to move so as to unlock the same. When the folding box is empty and recycled, the side plates are easy and convenient to unlock, and are difficult to be unlocked by an accidental triggering when using.
US10532848B2 Lightweight container base
A container including an opening defined by a finish portion, and a base at an end of the container opposite to the opening. The base includes a standing ring extending inward from a heal to a center pushup portion. The center pushup portion includes an pushup ring surrounding an inversion portion. In an as-blown position the inversion portion extends outward and beyond the pushup ring such that the inversion portion is further from the opening than the pushup ring. In a final position the inversion portion is inverted relative to the as-blown position such that the inversion portion extends inward so as to be closer to the opening than the pushup ring. The inversion portion is mechanically moved from the as-blown position to the filled position with an inversion device after the container has been filled to reduce vacuum or increase pressure within the container.
US10532847B2 Package having a plug seal closure
A package including: a container; and a plug seal closure operatively engaged with an open end of the container; wherein the container has; a closed end opposing the open end; a container wall extending longitudinally between the closed end and the open end about a longitudinal axis; an end seam extending at least partially across the closed end; and a longitudinal overlapping seam extending from the end seam, a portion of the overlapping seam extending longitudinally along the container wall between the closed end and the open end; wherein the open end is narrower than at least a portion of the container away from the open end of the container; and wherein the closed end and the container wall consist of a one-piece thermoplastic substrate.
US10532839B2 Egg sorting and packaging method and assembly
An egg sorting and packaging assembly comprising an endless egg conveyor, an egg supply device for supplying and moving eggs onto the endless egg conveyor, and one or more packaging lines associated with the endless egg conveyor. The one or more packaging lines are configured and arranged to receive eggs from the endless egg conveyor. The egg supply device is adapted and arranged to remove eggs from the supply device that would have to be placed on a position on the endless egg conveyor that is already occupied by an egg that could not be received in a packaging line, and leads the removed egg back to an egg supply line.
US10532838B2 Consumable authentication
A receptacle for a consumable material, such as a wire spool 2, to be loaded into a machine, such as a wire tying machine 18, comprises first and second indicating means 6, 12 for identifying the receptacle, wherein one of the indicating means 6 is separable from the receptacle.
US10532833B2 Space propulsion module having both electric and solid fuel chemical propulsion
A space propulsion module for fitting to spacecraft is provided. The space propulsion module includes a solid propellant chemical thruster including a main body, and at least one electric thruster. The at least one electric thruster is mounted on main body of the solid propellant chemical thruster.
US10532826B2 Lighting and collision alerting system
A collision avoidance system includes a sensor adapted to detect at least one vehicle in the vicinity of a predetermined area and generate target data relating to the at least one vehicle. An awareness engine receives the target data and evaluates the target data for a threat of a collision. An alerting system is adapted to alert the at least one vehicle in the event of a threat of a collision, the alerting system being activated by the awareness engine.
US10532821B2 Fluid system having a control valve and a monitoring system therefor
A fluid system includes a controller, a control valve, and a fluid manifold. A first solenoid may be connected to the fluid manifold, the control valve, and/or the controller. A second solenoid may be connected to the fluid manifold, the control valve, and/or the controller. A first pressure sensor may be in fluid communication with an output of the control valve. A second pressure sensor may be in fluid communication with the fluid manifold. The controller may be configured to control operation of the control valve via the first solenoid and the second solenoid according to a first fluid pressure obtained via the first pressure sensor and according to a second fluid pressure obtained via the second pressure sensor.
US10532815B1 Two vehicle transportation system
A first and a second aircraft are detachably coupled where the first aircraft is configured to perform a vertical landing using a first battery while the first aircraft is unoccupied and the unoccupied first aircraft includes the first battery. In response to detecting a second, removable battery being detachably coupled to the first aircraft, a power source for the first aircraft is switched from the first battery to the second, removable battery. After the switch, the first aircraft takes off vertically using the second, removable battery while occupied. The detachably coupled first aircraft and second aircraft are flown using the second aircraft (the power to keep the detachably coupled first aircraft and second aircraft airborne comes exclusively from the second aircraft and not the first aircraft).
US10532813B2 Dual purpose vehicle for air and ground transportation, and related methods
A vehicle for providing one or more people air and ground transportation includes a body, a wing, and a coupler that attaches the wing to the body. The body is configured to carry one or more people. The wing is moveable from a first position (ground mode) in which the wing does not generate lift as the body moves through the air, to a second position (flight mode) in which the wing does generate lift as the body moves through the air. The coupler is configured to hold the wing in the first and second positions, and to hold the wing as the wing moves from the first position to the second position, during which the wing rotates about a longitudinal axis. Some embodiments of the vehicle successfully combine aircraft design features with three-wheeled motorcycle design features to create an aesthetically pleasing vehicle that can be driven from an origin on the ground to a safe location for a conventional takeoff, and transitioned, in minimal time, from a road vehicle to an aircraft with safe, conventional controls that provide good handling characteristics on par or better than general aviation aircraft on the market today.
US10532812B2 Multi-hull seaplane
A multi-hull seaplane configured to eliminate most porpoising modes (only the low angle planing remains) by separating the forward and aft hulls and staggering them transversely so as the water flow from the forward hulls does not strike the rear hulls at planing speeds thereby eliminating afterbody induced porpoising. The forward and aft hulls are offset laterally with possible vertical offset and longitudinally to maintain lateral and longitudinal stability over all speed regimes.
US10532806B2 Low-noise novel thruster
The present invention discloses a low-noise novel thruster, in which a rotor casing is located at an air inlet side of a stator casing, at an inner middle portion of the rotor casing a rotor core is provided which is driven to rotate by a driving module; a rotor core is provided at in inner middle portion of the stator casing; the rotor casing is of a streamlined cylindrical structure with unequal diameter, and the main body of the rotor blade is parallel with the axial direction, and provided with a smooth curve in the rotating direction of the blade adjacent to an edge portion of an air inlet side. The present application provides a new thruster, which has same energy consumption and safety as propellers, but at a significantly greater thrust than the propeller, the more significant the advantage is at higher speeds.
US10532795B2 Flexible regasification and floating thermal energy storage
According to some embodiments, a flexible regasification system comprises a floating liquefied natural gas (LNG) storage vessel; a LNG vaporizer disposed on a jetty proximate the LNG storage vessel to vaporize the LNG into natural gas; and a thermal fluid source. The LNG storage vessel is coupled to the LNG vaporizer and supplies LNG to the LNG vaporizer. The thermal fluid source is coupled to the LNG vaporizer and sends heated thermal fluid to the LNG vaporizer for converting the LNG to natural gas, which converts the heated thermal fluid to a cooled thermal fluid. The cooled thermal fluid is discharged back to the thermal fluid source, comprising a closed loop. In particular embodiments, the thermal fluid storage comprises a floating vessel disposed near the jetty. In some embodiments, the cooled thermal fluid from the LNG vaporizer is first sent to a power plant or refrigeration plant.
US10532788B2 Bicycle operating device
A bicycle operating device is basically provided with a first base member, a lever and an operating unit. The first base member includes a first end portion and a second end portion. The first end portion is configured to be coupled to a handlebar. The second end portion is opposite to the first end portion. The first base member extends along a longitudinal direction from the first end portion to the second end portion. The lever is pivotally coupled to the first base member about a lever axis. The operating unit includes a second base member and an operating member. The second base member includes a mounting portion that is mounted to the second end portion of the first base member. The operating member is movably coupled to the second base member between a rest position and an operated position to operate a bicycle telescopic apparatus.
US10532782B2 Multi-legged independent mobile carrier
A multi-leg independent mobile carrier device, comprising: a base (1), a traveling mechanism (2), and a posture adjustment mechanism (3). The base (1) is used for carrying a human being or an object. The traveling mechanism (2) comprises a driving unit (21) connected to the base (1) and a connecting rod unit (22) rotatably connected to the driving unit. The traveling mechanism (2) is used for driving the base (1) to travel and get over any obstacles. The posture adjustment mechanism (3) is connected to the base (1) and used for keeping the human being or object balanced. The multi-leg independent mobile carrier device integrates a traveling mechanism and a posture adjustment mechanism. The posture adjustment mechanism is used for keeping the base balanced all the time and the traveling mechanism is used for driving the entire device to travel and turn around more flexibly. Therefore, the technical problem of a carrier device being unable to satisfy requirements of good obstacle performance, comfortable riding experience, and flexible traveling is effectively solved. The obstacle crossing ability of the multi-leg independent mobile carrier device is enhanced, and user experience is improved.
US10532781B2 Robotic device for providing vertical mobility
A robotic device for providing vertical mobility has a payload is disposed inside a central compartment and supported by a skid. The skid can move up and down through latch and hook pairs to keep intimate contact with the surface and cross over bumps. The apparatus uses a flexible seal to create a reliable vacuum chamber. The flexible seal comprises a foam ring inside fabric pocket. A plurality of rod and spring strips are configured to apply a downward force to the flexible seal to conform with surface curvatures. The fabric pocket fills in the gaps or seams to maintain a vacuum. The air flows inside a manifold and passes through a filter to avoid debris from damaging the vacuum motor assembly.
US10532778B2 Interlocking weldless connection for metal components
A weldless connection for connecting two components together, including first and second components having respective first faces which are disposed in flush engagement with each other, and having respective second faces which are planar and are substantially aligned with each other along a same plane, and a plate which is disposed so as overlap portions of the aligned second faces of the components. One edge of the plate is curved into a hook shape, a recess is formed into the second face of the first component and receives the curved edge of the plate therein for connecting the plate to the first component while permitting some relative movement between the plate and first component, and a portion of the plate which overlaps the second face of the second component is fixed thereto.
US10532777B2 Center floor panel for vehicle
A vehicle center floor panel is provided. A front end thereof is connected with a dash panel partitioning a front body of the vehicle and a vehicle interior room. A rear end thereof is connected with a rear crossmember disposed at a front end of a rear body to be crossed in a width direction of the vehicle. The center floor panel includes center floor members that have a U-shaped floor tunnel portion and a floor side extended portion formed integrally with the floor tunnel portion to extend toward sides from the floor tunnel portion, and spaced apart in a front and rear direction of the vehicle. Center crossmembers include a U-shaped cross tunnel portion to connect the floor tunnel portions and a cross side extended portion combined to the cross tunnel portion from both sides in a width direction of the vehicle to connect the floor side extended portions.
US10532775B2 Hood assembly incorporating a fluid reservoir
A motor vehicle hood assembly includes a hood shell and a fluid reservoir having a body including a stringer section and a plurality of finger sections that are connected to and extend from the stringer section along a longitudinal axis of the hood shell. The fluid reservoir may be provided packaged between the hood shell and an insulation layer of the hood assembly. A filling port is provided to assure the fluid is replenished by gravity once it's emptied from the reservoir.
US10532771B2 Method and apparatus for localizing a motor vehicle
A method, apparatus, and computer program for localizing a motor vehicle including transmitting via a wireless communication network configured within a parking lot, for a predetermined motor vehicle, a request that the predetermined motor vehicle carry out a predetermined action. After transmission of the request, a check whether a motor vehicle located within the parking lot is carrying out or has carried out the predetermined action. If the result of the check is that a motor vehicle located within the parking lot is carrying out or has carried out the predetermined action, the motor vehicle is authenticated as the predetermined motor vehicle and the predetermined motor vehicle is localized at a current position of the motor vehicle.
US10532767B2 Systems and methods for determining steering performance
Methods and apparatus are provided for determining steering performance. The method includes: generating a torque disturbance signal; applying the torque disturbance signal to a torque command of the steering system; measuring a value of torque on the steering system; recording the measured value and a value associated with the torque disturbance signal; computing at least one performance metric of the steering system based on the recorded measured value and the recorded value associated with the torque disturbance signal; and selectively improving a steering system based on the at least one performance metric.
US10532764B2 Motor driving device, failure diagnosis method for motor driving device, and electric power steering apparatus using motor driving device
A motor driving device is operable with low current consumption at low cost and can be started up without delay. The motor driving device includes inverter circuits, relay circuits, power supply stabilizing capacitors, pre-charge circuits, and a control unit. The inverter circuits individually drive coil sets of a motor. Each relay circuit is provided between a power supply and a corresponding one of the inverter circuits. Each capacitor is provided between a corresponding one of the relay circuits and a corresponding one of the inverter circuits. The pre-charge circuits, which are provided corresponding individually to the capacitors, each charge a corresponding one of the capacitors before the relay circuits are driven. The control unit controls the pre-charge circuits so that the pre-charge circuits charge the capacitors at mutually different timings or alternately when failure diagnosis is performed on the relay circuits.
US10532762B2 Energy-absorbing steering column
A steering column for a motor vehicle may include a steering column tube in which a steering spindle is mounted rotatably about a longitudinal axis. The steering column tube is fastened to a carrier connected to a vehicle chassis so that in normal operation the steering column tube is retained non-displaceably on the carrier, but is displaceable along the longitudinal axis in a crash event where a force that acts on the steering spindle exceeds a threshold value. An energy-absorption device may comprise a bending element that is connected to the carrier and the steering column tube and may be deformed in a crash event as a result of the longitudinal displacement of the steering column tube, thereby absorbing part of the energy of the steering column tube. The bending element may be at least partially surrounded by an insertion body, which prevents the binding element from contacting adjacent structural elements and deforms together with the bending element in a crash event.
US10532760B1 Systems and methods for an adjustable steering wheel
Systems and methods described herein are directed to an adjustable steering wheel. According to one aspect, a steering wheel includes a center post, a plurality of arc segments, a plurality of telescoping arms, and a plurality of modular segments. The plurality of arc segments have a fixed arc length relative to a center post axis defined by the center post. Each arm of the plurality of telescoping arms has a first end portion affixed to the center post and a second end portion non-removably affixed to an arc segment of the plurality of arc segments. The plurality of modular segments have adjustable arc lengths relative to the center post axis. Together the plurality of arc segments and the plurality of modular segments cooperate to define a circumference of the steering wheel that is orthogonal to the center post axis.
US10532758B2 Removable hand grip for wrapping around a bar
Some embodiments are directed to a hand grip for wrapping around a handlebar. The hand grip includes a first elongated coupling member, a second elongated coupling member, and a cover arranged between the first elongated coupling member and the second elongated coupling member. The first and/or second elongated coupling member include one or more protrusions arranged to be inserted into one or more holes or recesses of the bar. The hand grip can easily be attached to for example a handlebar of a baby stroller, and can easily be removed.
US10532756B1 Collapsible cart assembly
A collapsible cart assembly for storing and transporting a plurality of objects on a jobsite includes a box for containing objects on a jobsite. A plurality of wheels is each rotatably coupled to the box to roll along a support surface. A plurality of shelving units is provided and each of the shelving units is telescopically coupled to the box. Each of the shelving units selectively support objects for storage and for transportation. Moreover, each of the shelving units is positionable in a deployed position having the shelving units being distributed upwardly from the box and being spaced apart from each other. Each of the shelving units is positionable in a collapsed position having the shelving units being stacked on the box.
US10532754B2 System for controlling or monitoring a vehicle system along a route
System includes a control system used to control operation of a vehicle system as the vehicle system moves along a route. The vehicle system includes a plurality of system vehicles in which adjacent system vehicles are operatively coupled such that the adjacent system vehicles are permitted to move relative to one another. The control system includes one or more processors that are configured to (a) receive operational settings of the vehicle system and (b) input the operational settings into a system model of the vehicle system to determine an observed metric of the vehicle system. The one or more processors are also configured to (c) compare the observed metric to a reference metric and (d) modify the operational settings of the vehicle system based on differences between the observed and the reference metrics.
US10532753B2 Railcar coupler
A railcar coupler may include a coupler head comprising a shank and a head portion, the head portion defining a cavity for receiving a knuckle, a thrower, and a lock. The cavity can include a top pulling lug, a bottom pulling lug, and a thrower retaining lug. The top pulling lug can be configured to engage an upper knuckle pulling lug, and the bottom pulling lug being can be configured to engage a lower knuckle pulling lug. During operation of the railcar coupler, the ratio of the stress between the top pulling lug and the bottom pulling lug can be configured to be better balanced to help extend the life of the railcar coupler assembly.
US10532749B2 Systems and methods to adjust autonomous vehicle parameters in response to passenger feedback
Systems and methods for adjusting autonomous vehicle parameters in response to passenger feedback are provided. A method can include obtaining, by a computing system comprising one or more computing devices, passenger input data descriptive of one or more passenger experiences associated with one or more autonomous driving sessions, obtaining, by the computing system, one or more vehicle data logs descriptive of vehicle conditions associated with the passenger input data descriptive of one or more passenger experiences associated with the one or more autonomous driving sessions, determining, by the computing system using a machine-learned model, an adjusted vehicle parameter of an autonomous vehicle based at least in part on the passenger input data descriptive of one or more passenger experiences and the associated one or more vehicle data logs descriptive of vehicle conditions, and implementing, by the computing system, the adjusted vehicle parameter in an operation of the autonomous vehicle.
US10532746B2 Vehicle and controlling method thereof
A vehicle that provides an advanced driver assistance system (ADAS) recommendation function and a method of controlling the vehicle are provided. The vehicle includes a collection unit that is configured to collect behavior information of a driver and a controller that is configured to determine an advanced driver assistance system (ADAS) mode recommendable to the driver based on the collected behavior information and to output the determined ADAS mode.
US10532745B2 Vehicle and control method for vehicle
A monitor unit of a vehicle acquires an object left-right difference parameter corresponding to a command left-right difference parameter or corresponding to a measurement left-right difference parameter. The monitor unit compares the object left-right difference parameter and a first left-right difference threshold. If the object left-right difference parameter exceeds a first left-right difference threshold, the monitor unit limits the motive power of a first rotary electric machine and a second rotary electric machine.
US10532744B2 Apparatus, method and computer program for controlling a vehicle
An apparatus, method and computer program wherein the apparatus comprises: processing circuitry; and memory circuitry including computer program code; the memory circuitry and the computer program code configured to, with the processing circuitry, cause the apparatus at least to perform: obtaining information from at least one sensor wherein the information comprises a current location of a vehicle; using the obtained information to determine an autonomous evacuation strategy for the vehicle; and enabling the vehicle to access the autonomous evacuation strategy when an emergency is detected.
US10532743B2 Method for controlling motor torque in electric vehicle
A method for controlling a motor torque in an electric vehicle, includes the steps of: (a) determining a driving condition of the vehicle; (b) determining whether or not a predetermined limiting condition for a creep torque increase rate is satisfied when it is determined that the vehicle is decelerating in step (a); and (c) limiting the creep torque increase rate when the limiting condition for a creep torque increase rate is satisfied, and applying a creep torque of which the increase rate has been limited.
US10532742B2 Vehicle control system
In a steer by wire and idle stop vehicle, idle stop conditions for invoking an idle stop operation include that the traveling speed of the vehicle has fallen below a first value (10 km/h). When the vehicle speed is lower than the first value but higher than a second value (5 km/h), a steering actuator control unit 44 executes a position keep control whereby a steering motor 29 is electrically braked, and a reaction force actuator control unit 43 operates a reaction force motor 26 as a dynamic brake. When the vehicle speed has fallen below the second value in the idle stop operation, the steering motor control unit terminates the position keep control.
US10532733B2 Start control device for hybrid vehicle
A hybrid vehicle start control device is provided for a hybrid vehicle that ensures an EV reverse starting intended by a driver, even when an engagement command is issued to an engagement clutch that selects an ICE gear shift stage, when carrying out EV reverse starting. In this hybrid vehicle, a multistage gear transmission includes an EV shift actuator that selects an EV gear shift stage, and ICE shift actuators that select an ICE gear shift stage. A starting controller operates the EV electric actuator to select EV 1st of the multistage gear transmission at a time of starting, and that carries out an EV starting using the first motor/generator. At a time of an EV reverse starting, the starting controller carries out a control to the operating positions of the ICE shift actuators that prevent the selection of the ICE gear shift stage by the ICE shift actuators.
US10532730B2 Apparatus and method of reducing vibrations of hybrid electric vehicle
An apparatus for reducing vibrations of a two-cylinder engine for a hybrid electric vehicle includes a reference signal generator for generating a first reference signal and a first reference phase, a speed calculator for calculating a speed of the motor based on the position of the motor, a vibration extractor for extracting a first vibration signal based on the speed of the motor, a variable filter, a filter coefficient updater, a phase calculator, a phase shift compensator, a synchronization signal generator for generating a first synchronization signal synchronized with the first vibration signal based on a first reference phase transferred from the reference signal generator, the second phase difference transferred from the phase calculator and the first compensation value transferred from the phase shift compensator, an inverse phase signal generator, and a torque generator for generating a final command torque based on the first inverse phase signal.
US10532725B2 Position sensing system for a braking system
A position sensing system for a braking system has a rotor and a caliper assembly disposed at least partially around the rotor. The caliper assembly has a fixed mount bracket and a floating portion. At least two brake pads are attached to the floating portion, operable to exert a force against the rotor in response to a force through the floating portion. A first portion is coupled to the fixed mount bracket. A second portion is coupled to the floating portion such that the second portion moves in response to movement of the floating portion. A sensor assembly measures a distance between the first portion and the second portion. A wireless transmitter sends a signal from the sensor assembly to detached electronics, the signal representing the distance measured.
US10532723B2 Hydraulic device for controlling braking for farm vehicles and the like
A hydraulic device for controlling braking for farm tractors, earthmovers and like machines, comprises a master cylinder and brake booster. A piston of the brake booster defines first and second chambers which, under rest conditions, are in communication and, during braking, are cut off with the first chamber being put in communication with a discharge chamber of the master cylinder. The piston of the master cylinder is driven by a drive piston shaped to define with a plunger of the piston of the brake booster a hollow space through which the first chamber communicates with either the second chamber or the discharge chamber, depending on device operating conditions. In the plunger, a seat for a gasket-valve is arranged to cooperate with the drive piston, during braking, to prevent fluid leakage between the second and the first chamber as a consequence of the sliding of the drive piston caused by braking.
US10532722B1 Leaning control scheme for a fire apparatus
A fire apparatus includes a chassis, a body assembly, a front cabin, a front axle, at least one rear axle, a ladder assembly having a proximal end that is coupled to the chassis between the front axle and the at least one rear axle, a stability system, and a controller. The stability system includes a pair of front downriggers, a pair of rear downriggers, and an outrigger assembly coupled to the chassis between the front axle and the at least one rear axle. The front and rear downriggers are selectively extendable to engage a ground surface. The outrigger assembly includes a pair of outriggers that are selectively extendable from the body assembly to engage the ground surface. The controller is configured to facilitate controlling extension and retraction of the front downriggers, the rear downriggers, and the outriggers to lean the fire apparatus.
US10532714B2 Safety switching device for switching on and safely switching off an electrical load
A safety switching device for switching on and safely switching off an electrical load, comprising a failsafe evaluation/control unit, an output terminal for providing a potential, a switching element having a first working contact, wherein the potential is connectable to the output terminal via the first working contact, and an input terminal for receiving an input signal for operating the switching element via the evaluation/control unit. Additionally, the safety switching device comprises a separator having a connecting piece, a drive element and a separating element. The drive element is configured to mechanically move the separating element from a first position into a second position and the connecting piece and the first working contact electrically connect in series with one another the potential to the output terminal. Further, in the second position the separating element irreversibly separates the connecting piece into two pieces.
US10532711B2 Rear underrun protection system for a vehicle
An underrun protection system for arranging on a rear of a vehicle includes a crossmember and two support arms for supporting the crossmember and for mounting on a mounting structure of the vehicle. The underrun protection system further includes two connecting devices for mounting the crossmember on the support arms. The connecting devices serve as reinforcing parts for the partial reinforcement of the crossmember and/or the connecting devices are designed for adjustability along the crossmember.
US10532709B2 Safety control system for vehicles
According to one aspect of one embodiment of the present invention, a safety control system for using applications in vehicles, includes, a communication device having at least one of an input accessible from within the vehicle and an output communicated within the vehicle, at least one sensor operable to sense at least one condition related to vehicle operation, and data about distraction features of a running application, to and a controller communicated with the sensor and the communication device to selectively suppress at least one of said input and said output in response to a sensed parameter of said at least one condition being outside of a threshold. When an input is suppressed, the driver is prevented from accessing or inputting information into the communication device. When an output is suppressed, communication between the device and the driver of a vehicle is suppressed to, among other things, avoid distracting the driver during certain driving situations or conditions relating to the driver, vehicle and/or environment.
US10532707B2 Motor vehicle and method for producing a motor vehicle
A motor vehicle has a control device which is arranged in a cockpit module and has a cable harness, which includes at least one data and/or power cable, for connecting the control device to an on-board electrical system of the motor vehicle. The control device has at least one connection for making electrical contact with the cable harness. An improved utilization of the available installation space in the cockpit region and a shortening of the requisite length of the cable harness is obtained by the connection of the control device being arranged on a side of the control device which faces an interior of the motor vehicle.
US10532705B2 Resin vehicle body grounding structure
In a resin vehicle body grounding structure, a positive terminal of a battery is connected to positive terminals of a first load and a second load, a negative terminal of the battery is connected to a first grounding structure element, a negative terminal of the first load is connected to the first grounding structure element, a positive terminal of an alternator is connected to the positive terminal of the second load, the negative terminal − thereof is connected to a second grounding structure element, and the negative terminal of the second load is connected to the second grounding structure element.
US10532703B2 Car door upholstery protective shield and method of use of the same
A car door upholstery protective shield includes a one piece resilient body. The body includes a spine having a first end, a second end, a first side edge and a second side edge. A protective sheet depends downwardly from the first side edge. A first door engagement tab on the second side edge projects outwardly past the first end. A second door engagement tab on the second side edge projects outwardly past the second end. A cutaway gripping area in the spine creates a flex region in the spine, such that manual upward pressure in the gripping area causes the spine to bow upwardly in the flex region to bring the first end and the second end closer together and upon release of the manual pressure the spine resiliently returns to original shape and length.
US10532700B2 End surface-neutral positioning of a camera on a vehicle
A method is provided for determining a position for a camera on an outer skin of a vehicle, the position being determined such that the camera can detect an object at a visual reference point behind the vehicle. The method identifies a lateral surface which, in an initial position, is parallel to an XZ plane of the vehicle at a lateral distance from a central x-axis of the vehicle, the lateral distance depending on a maximum width of the vehicle. The method identifies an axis of rotation for the lateral surface which is parallel to a z-axis of the vehicle and which extends through the visual reference point. The method determines a point of intersection of the lateral surface rotated, starting from the initial position, about the axis of rotation with the outer skin of the vehicle. The method determines the position for the camera based on the point of intersection.
US10532698B2 Trailer angle detection using rear backup camera
A method for determining trailer angle includes determining angles of a trailer hitch relative to a data recording device via an angle measuring device while the trailer hitch pivots about a hitch ball of the device. While the trailer hitch pivots about the hitch ball of the device, trailer hitch information is determined responsive to processing of captured image data and responsive to determined angles of the trailer hitch. After determining trailer hitch information, data representative of the determined information is provided to an electronic device, which is disposed at a vehicle having a rear backup camera that has a field of view that encompasses a hitch ball of the vehicle and at least a portion of a hitch of a trailer hitched to the vehicle. Using the provided data, and responsive to processing of captured image data, an angle of the trailer relative to the vehicle is determined.
US10532696B1 Method for warning a driver of a vehicle about a potentially critical traffic situation
A method for warning a driver of a vehicle regarding a potentially critical traffic situation, having the steps of: detecting a potentially critical traffic situation for the vehicle, determining a hazard measure of the potentially critical traffic situation for the vehicle, and outputting a warning to the driver of the vehicle if the hazard measure of the potentially critical traffic situation reaches or exceeds a warning threshold. The warning threshold is adjusted as a function of the information of a self-learning map. A corresponding apparatus as well as the use thereof in a vehicle is also disclosed.
US10532695B2 Vehicle monitoring device, vehicle monitoring method and vehicle monitoring program
A vehicle monitoring device includes a determination unit that determines whether a following vehicle shown in an image taken by a camera that takes an image of a surrounding area of a host vehicle is a two-wheel vehicle or not, and a warning unit that issues a warning when an inter-vehicle distance between the following vehicle and the host vehicle becomes equal to or less than a first distance in a case where the following vehicle is determined not to be a two-wheel vehicle by the determination unit, and issues a warning when the inter-vehicle distance between the following vehicle and the host vehicle becomes equal to or less than a second distance, which is longer than the first distance, in a case where the following vehicle is determined to be a two-wheel vehicle by the determination unit.
US10532693B2 Diffused flexible LED linear light assembly
An undercarriage light assembly includes a light element, a translucent jacket exterior to and surrounding the light element, and an outer housing positioned exterior to and surrounding at least a portion of the translucent jacket. The outer housing includes a first side, a second side connected to the first side, and a third side connected to the second side. The first and third sides are angled toward one another. An opening between the first and third sides allows for light to pass from the light element through the outer housing.
US10532684B1 Method for displaying an image or scenery on a floor mat or floor liner
A method for applying an image to a floor mat or floor liner including applying a layer of ink to a first side of a clear applique; bonding, with a bonding agent, the first side of the clear applique to a surface of a substrate; and heating the applique and substrate to a first temperature such that the adhesive cures; heating the bonded substrate to a second temperature, such that the surface of the substrate becomes malleable; and forming a scene into the surface of the substrate.
US10532681B2 Seat including a head sensor
A vehicle seat for use in a vehicle comprises a seat body for engagement with a seated occupant's body. The seat body including: a seat base for receiving a seated occupant and a backrest extending upward from the base for supporting the seated occupant's back, and a headrest connected with the backrest and projecting upward from the backrest. The headrest includes a receiving face facing forward for engagement with the occupant's head in the event of a sudden change in velocity to ease rearward movement of the occupant's head.
US10532676B2 Removable car seat cover having a predetermined pre-weakened failure zone of a known bursting strength for facilitating reliable airbag deployment
A removable car seat cover for a car seat having an integral side airbag including a side panel having a predetermined pre-weakened failure zone that is pretreated by controlled laser ablation of the side panel. The pre-weakened failure zone is located at or adjacent to an airbag deployment area of a car seat when the car seat cover is installed on the car seat, and is in the form of an elongate strip extending along the side panel. The pre-weakened failure zone has a known bursting strength to thereby facilitate reliable deployment of the side airbag from the car seat as a result of tearing of the pre-weakened zone when the removable car seat cover is installed thereon.
US10532672B1 Adjustable firmness seat suspension and seat incorporating the same
An adjustable firmness seat suspension includes a seat frame, first and second spring members, and an intermediate tensioning member. The seat frame includes a first frame member and a second frame member spaced apart from and opposite one another. The first spring member is attached to the first frame member, the second spring member is attached to the second frame member, and the intermediate tensioning member is attached to and extends between the first spring member and the second spring member. The intermediate tensioning member is formed from a shape memory alloy (SMA) having a first length that provides a first spring tension of the seat suspension through the first and second spring members, and configured to alter its length to a second length that provides a second spring tension of the seat suspension through the first and second spring members in response to application of a tensioning signal thereto.
US10532671B2 Seat base assembly of a vehicle
A removable seat assembly for a vehicle, including a base assembly having a riser portion configured to support a seat; a frame structure coupled to and supporting the riser portion, the frame structure defining a first generally planar surface configured to support a floor section; a seat dolly coupled to the frame structure, the seat dolly including a plurality of wheels for moving the seat assembly from a first position to a second position; a floor base assembly defining a substantially planar surface for receiving the plurality of wheels of the seat dolly as the seat assembly is moved from the first position to the second position; and a mounting bracket configured to releasably lock the seat dolly to the floor base assembly.
US10532670B2 Seat recliner for vehicle
Disclosed is a seat recliner for a vehicle, the seat recliner including: a first flange provided with a plurality of guide parts being spaced apart from each other, with guide spaces defined between the guide parts; a plurality of locking gears disposed in the guide spaces of the first flange respectively, configured to slide forward and backward along the guide parts in a radial direction, and provided with external teeth at an outer end of each of the locking gears; and a second flange coupled with the first flange to be rotatable relative thereto, formed in a shape covering the guide parts and the locking gears, and configured to be engaged with the external teeth of the locking gears.
US10532668B2 Striker mounting structure of rear seat back for vehicle
A striker mounting structure of a rear seat back for a vehicle is disclosed, which comprises a mounting bracket with assemble hole; a striker fixedly coupled to the mounting bracket inserted into the assemble hole, and detachably coupled to a seat back of a rear seat; and a seat belt retractor mounting portion at which a seat belt retractor is mounted, and coupled to the mounting bracket, so that it is possible to reduce weight and cost.
US10532663B2 Electric vehicle overhead charging system and method of use
Techniques for electric vehicle systems, and in particular to an electric vehicle emergency charging system and method of use. In one embodiment, a system for charging a moving electric vehicle is provided, the system comprising: an electrical storage unit disposed on the electric vehicle; a charging panel in electrical communication with the electrical storage unit; a vehicle controller that determines if the electrical storage unit requires charging and configured to determine if an overhead power source is available to charge the electrical storage unit; wherein the charging panel receives the charge from the overhead power source and charges the electrical storage unit.
US10532662B2 Eddy current braking device for rotary systems
An apparatus has a first portion of a magnetic braking system with a first element disposed thereon. The first portion rotates about an axis. The position of the first element is a fixed distance from the axis. A second portion of the magnetic braking system has a second element disposed thereon. A spring biases the rotatable first portion a first distance from the second portion. Upon application of a force to one of the portions, the relative position of the rotatable first portion to the second portion is reduced to a second distance less than the first distance.
US10532661B2 System and method for heating electrified vehicle
An exemplary electrified vehicle includes a passenger cabin, and an infrared heater configured to radiate heat for conditioning the passenger cabin. The vehicle further includes a heating device configured to heat airflow for conditioning the passenger cabin. Further, the vehicle includes a controller configured to selectively command a change in an output of the heating device based on an amount of power available to the infrared heater.
US10532660B2 Cluster for vehicle
A cluster for a vehicle may include a center module including a center display unit, and a side module mounted to a side surface of the center module, and including a side display unit and the side module may be removably coupled to the center module.
US10532659B2 Occupant monitoring systems and methods
Various implementations include an occupant monitoring system (OMS) for monitoring at least one occupant in a vehicle. The OMS includes a mounting bracket coupled to a rotatable portion of a steering wheel assembly, a housing coupled to the mounting bracket, at least one imaging unit disposed within the housing, and at least one lens disposed adjacent the housing and imaging unit and facing an expected position of at least one vehicle occupant and configured for allowing light to pass through to the imaging unit. The mounting bracket extends upwardly from the steering wheel assembly adjacent a central portion thereof. The housing has a back surface that is disposed adjacent a back cover of the steering wheel assembly. The imaging unit has a field of view inside of the vehicle and is configured to capture an image signal corresponding to an imaging area within the field of view.
US10532658B2 Health measurement system for vehicle's driver and warning method using the same
A health measurement system for a vehicle driver and a warning method using the same are disclosed. The health measurement system includes an Internet of Things (IoT) device and a controller. The controller performs health scanning of a driver through the IoT device, and informs the driver of a result of the health scanning. The controller determines a necessary condition of the health scanning of the driver by analyzing traveling environment information, and performs the health scanning only when the necessary condition of the health scanning is satisfied.
US10532652B2 Flap panel and motor vehicle
The invention relates to a panel (6) of flaps (9) for an air intake (2, 3) of a motor vehicle (1) comprising a plurality of flaps (9) mounted with the ability to pivot about a respective longitudinal axis of pivoting (A), the longitudinal axes of pivoting (A) extending parallel to one another and being arranged side by side, characterized in that the alignment of the longitudinal axes of pivoting (A) lies within a curved surface (S). The invention also relates to a motor vehicle (1) comprising such a panel (6) of flaps (9).
US10532651B2 Motor vehicle having an air guide and an air duct
A motor vehicle includes air-guiding means and an air duct. The air-guiding means are configured to guide incident air into the air duct. The air-guiding means are arranged such that the incident air flows from below into a first end section of the air-guiding means during an intended use of the motor vehicle.
US10532644B2 Vehicle body structure
A vehicle body structure is provided that has fewer parts and allows a seal member securely sealing a gap between a vehicle body and a door to be attached thereto. The vehicle body structure has a door that covers and uncovers a door opening formed in a vehicle body. The door has a first garnish that is located on an outer side of a vehicle than the door, and a seal member that is attached to the first garnish and seals a gap between the door and the vehicle body. The first garnish has an insertion groove defined by a contact wall extending in a direction which is orthogonal to a lateral direction, and the seal member is inserted in the insertion groove so as to be in contact with the contact wall.
US10532642B2 Convertible sliding top
Disclosed herein are embodiments of a convertible sliding top assembly for use with a vehicle. The convertible sliding top assembly can create an opening on the top of the vehicle by rotating a plurality of arms and folding over a soft cover. The assembly can be designed and shaped to improve aerodynamics when the vehicle is moving and prevent the buildup of water on the soft cover.
US10532639B1 Holding assembly for a sunroof rail system
A holding assembly in a vehicle sunroof includes: a housing; a sunroof panel; a rail extending in a front-rear direction of the sunroof, the sunroof panel being slideably connected to the rail; a rail guide extending in the front-rear direction and including a rail channel extending a length of the rail guide from a first end of the rail guide to a second end of the rail guide; and a front wall extending in the front-rear direction and including a support arm and a lateral restrictor, wherein the support arm extends towards the rail guide and below the rail channel at the second end of the rail guide, and the lateral restrictor has a planar shape parallel to the length of the rail guide, is attached to the support arm, and is in contact with an exterior face of the rail channel at the second end of the rail guide.
US10532638B2 Mounting structure for mounting interior component
A mounting structure for mounting an interior component to a door trim body includes: a rear locking protrusion including a first portion protruding from a back surface of the interior component and a second portion extending from a distal end of the first portion toward a front of a vehicle; a rear mounting hole in a rear edge section of the door trim body and opposed to the rear locking protrusion; a locking protrusion protruding from the back surface toward the door trim body and is disposed closer to a front of the vehicle relative to the rear locking protrusion; and a mounting hole in a section of the door trim body at a position closer to the front relative to the rear mounting hole and opposed to the locking protrusion. The second portion of rear locking protrusion is locked to a hole edge of the rear mounting hole.
US10532635B2 Attachable sun visor system
An attachable sun visor system includes a sun visor extension assembly including a sun shade panel, an extendable rod having a first-end, a second-end, and a mounting member. The sun shade panel is configured to attach to a rod of a stationary sun visor in a vehicle and swivel from being adjacent to the stationary sun visor during non-use to being perpendicular to the stationary sun visor during an in-use condition to provide an effective shade area in combination with the stationary sun visor.
US10532630B2 HVAC system of vehicle
A heating, ventilating, air conditioning (HVAC) system of a vehicle includes: a battery circulation line having a battery radiator, a main valve, a high voltage battery core, and a cooling heat exchanger so as to circulate a first coolant therethrough, with the cooling heat exchanger being provided to be heat-exchangeable with an indoor HVAC refrigerant line; a branch line including a water heating heater and selectively connected to the battery circulation line through the main valve; and a controller selectively cooling or heating the high voltage battery core by controlling an operation of the main valve, the water heating heater, and the indoor HVAC refrigerant line.
US10532625B2 Adjustable spring support
Adjustable spring support includes a first spring plate and a second spring plate, wherein at least one of the spring plates is axially adjustable relative to the other spring plate by an actuator, wherein the actuator is supplied with pressure medium via a pump which is driven by a motor and which is connected to a supply receptacle, wherein the motor, the pump and the supply receptacle form a constructional unit, and the constructional unit provides a cylindrical surface of the actuator.
US10532615B2 Pneumatic tire manufacturing method, and pneumatic tire
A pneumatic tire manufacturing method is provided in which raw cover molding is suitably performed with no, or a minimal amount of, down-stitching in the manufacture of SOT-structure pneumatic tires; also provided is a pneumatic tire. This pneumatic tire manufacturing method involves: a step in which a sidewall, an inner liner, and a ply are bonded on a first molding drum, a pair of beads is set, and the tread side part is formed on the side wall, forming a first cover; a step in which a breaker and band are bonded on a second molding drum and the tread center part is formed on the band, shaping the tread ring; a step in which the first cover is inserted inside of the tread ring and the first cover is inflated, bonding the tread ring and the first cover with pressure; and a step in which the sidewall is folded back towards the lateral surface of the inflated first cover and bonded to the lateral surface of the first cover, and the tread side part and the tread center part are bonded together.
US10532612B2 Tire comprising a layer of circumferential reinforcing elements
Tire comprising a crown reinforcement formed of at least two working crown layers of reinforcing elements. First layer C of rubber compound is placed between ends of the two working crown layers. Second layer S of polymer compound is in contact with at least one working crown layer and with the carcass reinforcement. The crown reinforcement includes at least one layer of circumferential reinforcing elements. The elastic modulus under tension at 10% elongation of first layer C is less than 8 MPa, the maximum value of tan(δ) of first layer C is less than 0.100. The second layer S is made up of a filled elastomer blend having a macro dispersion coefficient Z greater than or equal to 65 and a maximum tan(δ) value less than 0.100, and its complex dynamic shear modulus G*, measured at 10% and 60° C. on the return cycle, is greater than 1.35 MPa.
US10532611B2 Tire and wheel assembly having angled interfaces
A tire is configured to be received by a wheel having at least one angled surface. The tire includes a tread portion, a first sidewall, and a second sidewall. The first sidewall has a first outer surface, a first inner surface, and a first projection extending inwardly from the first inner surface. The first projection has a first angled surface configured to engage a first corresponding surface of a wheel. The second sidewall has a second outer surface, a second inner surface, and a second projection extending inwardly from the second inner surface. The second projection has a second angled surface configured to engage a second corresponding surface of the wheel.
US10532610B2 Bicycle rim with brake track
A rim for a bicycle includes a radially outer tire-engaging portion, a radially inner spoke-engaging portion, a first sidewall and a second sidewall spaced apart from the first sidewall. A brake track is located on the first and second sidewalls including a plurality of grooves formed therein. Each of the plurality of grooves has a radially innermost point and a radially outermost point, wherein the radially outermost point is circumferentially aft of the radially innermost point relative to a forward circumferential travel direction of the rim.
US10532609B2 Method for traversing surface with magnetic omni-wheel
A method for traversing a magnetically inducible surface using a multidirectional wheel is provided. The method includes providing a vehicle having the multidirectional wheel, rotating a hub of the wheel along a first axial direction of rotation, continuing rotation of the hub of the wheel so as to cause a first roller disposed about a periphery of the hub to move out of contact with a first portion of the magnetically inducible surface and to cause a second roller disposed about the periphery of the hub in a plurality of rollers to contact a second portion of the magnetically inducible surface, wherein at least one roller among the plurality of rollers is in contact with the magnetically inducible surface throughout rotation of the wheel, and wherein the flux of the at least one magnet is concentrated toward portions of the surface being traversed adjacent to one or more of the plurality of rollers throughout rotation of the wheel.
US10532599B2 Ring binder mechanism
A ring mechanism has pivoting hinge plates supported by a housing so pivoting of the hinge plates can open and close rings for holding the loose-leaf pages. The mechanism has an actuator including a lower arm for moving the hinge plates to open the rings and an upper arm for moving the hinge plates to close the rings. The upper arm has a hook thereon. An intermediate connector comprises a cross bar captured by the hook on the actuator. The intermediate connector connects a travel bar to the actuator so movement of the actuator to pivot the hinge plates causes longitudinal movement of the travel bar in the housing. A locking element is moveable with the travel bar between a locking position and non-locking position.
US10532598B2 Ring binder mechanism
A ring mechanism has pivoting hinge plates supported by a housing so pivoting of the hinge plates can open and close rings for holding the loose-leaf pages. The mechanism has an actuator including a lower arm for moving the hinge plates to open the rings and an upper arm for moving the hinge plates to close the rings. The upper arm has a hook thereon. An intermediate connector comprises a cross bar captured by the hook on the actuator. The intermediate connector connects a travel bar to the actuator so movement of the actuator to pivot the hinge plates causes longitudinal movement of the travel bar in the housing. A locking element is moveable with the travel bar between a locking position and non-locking position.
US10532595B2 Printing apparatus, method for controlling same, and storage medium
A printing apparatus includes a discharge unit that discharges ink onto a print medium based on print data, a power transmission unit that to wirelessly supplies power to the discharge unit for discharging the ink, and a control unit that controls the power to be supplied by the power transmission unit based on the print data.
US10532594B2 Recording apparatus
A recording apparatus includes a recording head, an apparatus main body, a document cover, and a front cover. The apparatus main body houses the recording head therein and has outer surfaces including a document placement surface being an upper surface and a front surface which is adjacent to the document placement surface and which intersects the document placement surface. The document cover is able to be opened/closed in the document placement surface being the upper surface of the apparatus main body. The front cover is able to be opened/closed in the front surface of the apparatus main body. A hand-holding recess used to open the document cover and also used to open the front cover is positioned at part of a portion of the apparatus main body where the document placement surface being the upper surface and the front surface intersect each other.
US10532589B2 Printing apparatus and method for controlling printing
A printing apparatus includes a printing unit that prints on a front surface of a medium, a detection unit that receives reflected light of light emitted on a back surface of the medium, and a control unit that stops printing based on a detection result of the detection unit. In a case in which a second image is to be printed on the front surface of the medium of which back surface a first image being printed, when a range in which the first image is printed on the back surface of the medium is defined as a first range and a range corresponding to the first range on the front surface of the medium is defined as a second range, when printing the second image in the second range, the control unit continues printing irrespective of the detection result of the detection unit.
US10532587B2 Printing apparatus and printing method
The printing apparatus performs inkjet printing and includes an inkjet head that ejects ink to a medium, and an ultraviolet irradiator that irradiates the ink on the medium with ultraviolet light so as to heat the ink. The ink contains solvents. The solvents include a low-boiling solvent and a high-boiling solvent having a higher boiling point than the other, and the ink contains 20 wt. % or more of the low-boiling solvent and 20 wt. % or more of the high-boiling solvent. In at least part of a duration of time until the solvents in the ink are completely evaporated, an energy line irradiator irradiates the ink on the medium with an energy line, so that a temperature of the ink on the medium increases to a degree higher than or equal to the boiling point of the low-boiling solvent and lower than the boiling point of the high-boiling solvent.
US10532585B2 High-turnaround, closed-loop, direct to garment printing
In one embodiment, a high-speed, closed-loop fabric printer comprises a plurality of consecutive stations that can be managed by a single operator. In particular, shirts or other fabric garments may be individually loaded and secured on a pallet by an operator, and the loaded pallets may then cycle through a plurality of unmanned stations positioned along a contiguous path (e.g., oval). The stations may be configured for pretreating the fabric surface, drying and pressing the pretreated fabric with heat, and then inkjet printing a selected image, among others. In this manner, a “wet-to-dry-to-wet” direct to garment (DTG) printing process may thus be achieved, along with optimal controls for maximum adaptability. Furthermore, due to the closed-loop design, a recently printed fabric product returns to the operator to be unloaded at the position in which a new unprinted fabric is loaded, allowing for increased throughput and minimal operator requirements.
US10532568B2 Fire pulse width adjustment
First electronics may determine a count of bubble jet resistors to be fired by a fire pulse group. A fire pulse generator may generate a fire pulse train for bubble jet resistors, the fire pulse train comprising a precursor pulse and a firing pulse separated by a dead time. Second electronics may adjust a width of the fire pulse for the bubble jet resistors of the fire pulse group by maintaining a first edge of the fire pulse relative to the precursor pulse and adjusting a second edge of the fire pulse relative to the precursor pulse based upon the determined count for the fire pulse group.
US10532567B2 Piezoelectric actuator, method for manufacturing same, and liquid discharge head
A piezoelectric actuator has a ground substrate layer, an intermediate layer containing at least one of Ti and TiO2 on the ground substrate layer, an electrode layer containing Pt on the intermediate layer, and a piezoelectric layer containing lead zirconate titanate on the electrode layer, in which the lead zirconate titanate contained in the piezoelectric layer is preferentially oriented in the (100), (001), or (110) direction, the Pt contained in the electrode layer is preferentially oriented in the (111) direction, and the half width of the rocking curve in the (111) plane of the Pt contained in the electrode layer in X-ray diffraction is 1° or more.
US10532562B2 Droplet ejecting device
A droplet ejection device has a nozzle head with a plurality of ejection units, each of which includes a nozzle, a duct connected to the nozzle, and an electromechanical transducer arranged to create a pressure wave in a liquid in the duct so as to expel a droplet of the liquid from the nozzle. The device further includes an electronic control circuit arranged to apply control signals to the transducers and to receive detection signals that are generated in the transducers in response to the transducer being exposed to pressure fluctuations. The nozzle head includes a reference duct which has an electromechanical transducer serving as a reference transducer. The control circuit is arranged to subtract a detection signal of the reference transducer from a detection signal of at least one of the ejection units.
US10532556B2 Control of solidification in laser powder bed fusion additive manufacturing using a diode laser fiber array
A method of method of forming or repairing a superalloy article having a columnar or equiaxed or directionally solidified or amorphous or single crystal microstructure includes emitting a plurality of laser beams from selected fibers of a diode laser fiber array corresponding to a pattern of a layer of the article onto a powder bed of the superalloy to form a melt pool; and controlling a temperature gradient and a solidification velocity of the melt pool to form the columnar or single crystal microstructure.
US10532555B2 3D printing colorization
In one aspect, methods of printing a color 3D article are described herein. In some embodiments, a method described herein comprises receiving data representing a surface colorization of the article, and transforming the data representing the surface colorization of the article into voxel data of the article. The voxel data comprises (a) location values and at least one of (b) color values and (c) transparency values for a plurality of columns of voxels normal or substantially normal to a surface of the article. The method further comprises selectively depositing layers of one or more build materials onto a substrate to form the article in accordance with the voxel data. In addition, at least one column of the plurality of columns of voxels exhibits a surface color resulting from a combination of colors of a plurality of voxels of the column.
US10532554B2 Three dimensional printing system with automation features
A three dimensional printing system includes a vertical support, a support plate, a resin vessel, a resin handling module, a latch, and an interface mechanism. The support plate has a proximal end affixed to the vertical support and extends along a first lateral axis to a distal end. The resin vessel is supported by the support plate and includes a vessel body and a transparent sheet. The vessel body has a latch feature formed therein. The resin handling module includes a fluid outlet for dispensing resin into the resin vessel. The interface mechanism is configured to move the latch into engagement with the latch feature and to move the resin handling module from a non-operating position to an operating position whereby the fluid outlet is operably positioned over a portion of the resin vessel.
US10532549B2 Splices comprising honeycomb cores supported by tie clips and methods of forming thereof
Provided are splices, comprising honeycomb cores and adhesive layers with tie clips supporting the honeycomb cores. Also provided are methods of forming such splices. Each tie clip includes two legs and a bridging portion joining the legs. When forming a splice, an adhesive layer is positioned between two honeycomb cores. One leg of the tie clip is inserted into the full cell of one honeycomb core, while the other leg is inserted into the full cell of the other honeycomb core. The bridging portion extends across the adhesive layer. While curing the adhesive layer, the tie clip supports the honeycomb cores with respect to each other and maintains their orientation. The tie clip becomes a part of the splice. The tie clip may be buried in the honeycomb cores without extending above the first face of the splice.
US10532542B2 Cellulose ester multilayer interlayers
An interlayer structure having a cellulose ester layer for use in structural laminates is described herein. The cellulose ester layer provides rigidity and support to multilayer interlayers comprising an array of different layers. Due to the diverse properties of the cellulose ester layers, the present interlayers can be useful in producing structural laminates having high stiffness and which possess good optical clarity for a variety of applications, including outdoor structural applications.
US10532538B2 Stretch release adhesive, housing assembly and electronic device
The present disclosure provides a stretch release adhesive, a battery assembly, a housing assembly, and an electronic device. The stretch release adhesive includes a base; and a plurality of adhesive portions spaced apart from one another, each of the adhesive portions being provided on a surface of the base.
US10532533B2 Adhesive label, facestock for an adhesive label and adhesive label laminate
An adhesive label and an adhesive label laminate includes a uniaxially in machine direction oriented multilayer facestock comprising a printable skin layer comprising more than 50 wt. % of linear low density polyethylene(s) and less than 50 wt. % of propylene polymer(s), and an adhesive receiving skin layer comprising at least 50 wt. % of propylene homopolymer(s) and at least one of the following modifiers: hydrocarbon resin, styrene block copolymer, and olefin block copolymer. Further use of an adhesive label for labelling of an article and a labelled article are also disclosed.
US10532532B2 Compact shredder and compactor
A shredder includes a feed screw that pushes the items to be shredded and compacted towards an opening in the shredder via a restrictor that includes a pipe portion leading to the opening in the shredder, the shredder includes a drive motor driving a miller screw which shreds the items to be shredded into acquired size against a cutter plate fastened to a cutter housing to form shredded items, and forces the shredded items into a press chamber.
US10532531B2 Device for winding bead ring-binding thread
A bead ring bonding cord winding apparatus includes a feed roller that feeds a bead ring, which is formed by winding a wire a multiple number of times, in a circumferential direction of the bead ring, a gripping member that grips an initiating end of a bonding cord, and a rotation member that rotates past an inner side and an outer side of the bead ring while holding the bonding cord. In the bead ring bonding cord winding apparatus, while the bead ring is fed in the circumferential direction, the rotation member is rotated past the inner side and the outer side of the bead ring to spirally wind the bonding cord around the bead ring. The gripping member is located at an upstream side of the rotation member in the feeding direction of the bead ring.
US10532527B2 Method for the production of a bladder accumulator and bladder accumulator produced according to said method
A method for the production of a bladder accumulator (10) that separates two media chambers (16, 18) from one another in a storage housing (12) by a bladder body (14). The following production steps include extruding a plastic tube over the bladder body (14), shaping the plastic tube with the integrated bladder body (14) in a molding tool that corresponds to a predeterminable plastic core container (20), and winding at least one plastic fiber from the outside on the plastic core container (20) for the purpose of creating the storage housing (12).
US10532525B2 Method for preparing sapphire lens and sapphire lens
A method for preparing a sapphire lens includes the following steps: sequentially forming an ink layer and a coating film layer on one surface of a large polymeric membrane; laser-cutting the obtained large polymeric membrane to form two or more small polymeric membranes that are as thick as the large polymeric membrane; laminating the surface of the small polymeric membrane that does not contain the ink layer and the coating film layer to one surface of a sapphire sheet, such that an adhesive layer is formed between the small polymeric membranes and the sapphire sheet, wherein the sapphire sheet has a thickness of 0.3 to 1.5 mm, and the polymeric membrane has a thickness of 0.02 to 0.2 mm; and pressing the obtained sheet material to remove bubbles, thereby obtaining a sapphire lens.
US10532524B2 Method of repairing damage of aircraft engine components made of weldable thermoplastic materials
Disclosed is a method of repairing damage of an aircraft engine component made of or comprising weldable thermoplastic material, which method comprises welding of the weld filler material into an initially prepared damaged area. Also disclosed are the use of plastic welding technique for repairing damaged aircraft engine components made of weldable thermoplastic materials.
US10532521B2 Method of fabricating a composite material part having a body integral with one or more platforms
A method of fabricating a composite material part having a body secured to at least one platform present at one end of the body, the method including using the fiber blank to form a preform for the part that is to be made by folding out segments of the second and third portions that are not interlinked with the first portion on opposite sides of the first portion, by shaping the folded-out segments of the second and third portions to form preform portions for a platform of the part to be fabricated, and by folding down the segment of the first portion in order to fill in the groove present in the gap between the second and third portions; and densifying the preform with a matrix in order to obtain a part made of composite material having at least one integrated platform.
US10532518B2 Hybrid metallic/composite joint with enhanced performance
A metallic/composite joint may comprise a composite member having a flared end or an angled end, a liner perimetrically surrounding the composite member, and a metallic member perimetrically surrounding the liner. A first side of the liner contacts the composite member and a second side of the liner contacts the metallic member. The liner perimetrically surrounds at least a portion of the flared end. A through-thickness compressive stiffness of the liner may be less than a similar stiffness of the composite member.
US10532516B2 Shaping method, shaping system, and shaping device
The shaping method for shaping a 3D object includes shaping execution data generating step of generating shaping execution data indicating the 3D object in a format corresponding to a shaping device; and shaping executing step of shaping the 3D object with the shaping device based on the shaping execution data, the 3D object being shaped using at least a shaping material of plural colors, wherein the shaping execution data generating step is a step of generating the shaping executing data based on 3D object data indicating the 3D object in which at least one part is colored, the shaping execution data being generated by at least carrying out color conversion using a shaping material profile or a profile corresponding to the shaping material of plural colors, and the color conversion being carried out using the plurality of shaping material profiles different from each other.
US10532515B2 Additively manufactured component with locator element for aligning sub-components
A method that includes additively manufacturing with an additive manufacturing (AM) system a sub-component that has a locator element. Using a control system of the AM system for positioning a first location of the locator element. Selectively placing a portion of another sub-component adjacent to the locator element, based on the positioning. Then attaching the second sub-component to the first sub-component in a region, wherein the region is based on the positioning knowledge from the control system so as to make a component. A component that comprises a first sub-component that has an AM locator element; and a second sub-component attached to the first sub-component, wherein the locator element is attached to the second sub-component within the same additive manufacturing build chamber as the first sub-component.
US10532509B2 Biaxial stretching and blow molding device
A biaxial stretch blow molding device comprises: a first guide shaft 57 which is erected on an upper base 51 and to which a blow core fixing member 54 is slidably coupled; a second guide shaft 67 erected on the stretch rod fixing member 56; a support member 59 fixed to the first guide shaft 57 and provided with a guide hole 68 through which the second guide shaft 67 is slidably inserted; a first drive device 63 that moves the blow core fixing member 54 forward and backward independently of the stretch rod fixing member 56; and a second drive device 70 that moves the stretch rod fixing member 56 forward and backward independently of the blow core fixing member 54.
US10532508B2 Seal ring for vent saddle in extrusion barrel
A sealing device for sealing a venting port of an extrusion apparatus. The sealing device includes a saddle having a saddle counter bore and a seal ring positioned in the saddle counter bore of the saddle. The sealing device also includes a barrel counter bore provided in a barrel of the extrusion apparatus. The saddle counter bore and the barrel counter bore are dimensioned to receive the seal ring, wherein when the seal ring is positioned in the saddle counter bore and the barrel counter bore, a seal is formed between the seal ring in all range of processing temperatures, the saddle and the barrel to prevent the unwanted leakage of high pressure melt.
US10532504B2 Apparatus and method usable with an injection molder for producing articles
An apparatus usable with an injection molder for producing articles includes a first mold support including a first mold, and a second mold support including a second mold and a first die. The first mold support is movable relative to the second mold support between a first position and a second position. In the first position, the first mold and the second mold being brought together to form an injection molded article include a body having at least one protrusion extending outwardly from the body and facing the second mold. In the second position, the first mold and the first die being brought together to subsequently form the article, the first die selectively subsequently forming an altered cross sectional region in at least a portion of the protrusion, forming an undercut in the altered cross sectional region or between the altered cross sectional region of the subsequently formed protrusion and the body.
US10532503B2 Optical fiber re-coating device
An optical fiber re-coating device of the invention includes an optical fiber coater that includes: a pair of glass members having grooves formed thereon; and two bases on which the respective glass members are provided, wherein at least one of the paired glass members has a cross section in a direction vertical to a mounting surface of the bases, the cross section is formed in a trapezoidal shape, the groove is provided on a short side of the trapezoidal shape, and an inclined surface of the glass member including an inclined side of the trapezoidal shape is pressed, and the glass member is thereby fixed to the base.
US10532502B2 Container and label
The present invention is a container having a label that is embedded in the container and a method of temporarily marking the container over the label. The container is sufficiently transparent to allow indicia formed on the label to be ascertained through a wall of the container. The exterior wall of the container may be written upon with a marker that leaves marks that are erasable from the exterior of the container. A method of producing the container is described.
US10532497B2 Vulcanizing mould with enhanced sealing
A mould (10) for a tire, comprising two shells (30) that are each intended to mould a lateral sidewall of the tire, a ring of sectors (20) intended to mould a tread of the tire, each sector (20) of the ring of sectors comprising a radially inner face (21) having a moulding lining (22). The mould (10) has microstructures (50) that are designed to fill a clearance between two moulding linings (22) of adjacent sectors (20) and/or between a moulding lining (22) of one sector (20) and a shell (30), when the mould is closed.
US10532496B2 Methods for manufacturing bulked continuous filament
A method for manufacturing bulked continuous carpet filament, the method comprising: (1) reducing a chamber pressure within a chamber to below about 5 millibars; (2) after reducing the chamber pressure to below about 5 millibars, providing a polymer melt to the chamber; (3) separating the polymer melt into at least eight streams; (4) while the at least eight streams of the polymer melt are within the chamber, exposing the at least eight streams of the polymer melt to the chamber pressure of below about 5 millibars; (5) after exposing the at least eight streams of the polymer melt to the chamber pressure of below about 5 millibars, recombining the at least eight streams into a single polymer stream; and (6) forming polymer from the single polymer stream into bulked continuous carpet filament.
US10532493B2 Installation and a method for forming a fiber preform as a body of revolution presenting a profile that varies in radial section
An installation for shaping a fiber preform as a body of revolution presenting a profile that varies in radial section, the installation including a storage mandrel for storing a fiber texture, follower rollers, and a mold in the form of a body of revolution on which the fiber texture is to be shaped by winding, the follower roller(s) being placed between the storage mandrel and the mold in the form of a body of revolution. The storage mandrel, each follower roller, and the mold present radii across their axial widths that vary to define outer surfaces having profiles in relief. A follower roller has sectors releasably fastened on the outer surface of the roller, each sector extending over a fraction of the circumference of the roller and over all or part of the axial width of the roller.
US10532490B2 Plasticating apparatus screw having grooves of varying angles and depths
A screw for a plasticating apparatus has one or more helical flights. A portion of the screw has a plurality of advancing grooves arranged in a noncontinuous helix cut in the screw. The advancing grooves are dimensioned to receive material therein as the material is conveyed through the barrel. The screw has a plurality of noncontinuous cross-cut grooves traversing one or more of the advancing grooves. The cross-cut grooves have a second helix angle greater than the first helix angle and less than ninety degrees; and/or one or more of the cross-cut grooves have a third helix angle of about ninety degrees.
US10532486B2 Method for producing cutting blades
Disposable cutting blades and method for producing disposable cutting blades with profiled cross sections for a device for chipping wood. The method includes heating a primary material of a hardenable material in a soft-annealed state having a worked surface to a temperature above room temperature, but below a conversion temperature Ac1, rolling the primary material to form a profile blank with at least one precisely gaged guide path in a base body in cross section and with an increased thickness of at least one edge region, a metal-removing working of at least one edge region in a longitudinal direction of the profile blank to form a cutting edge and to form scratching edges in a spaced manner directed perpendicularly to the cutting edge, and continuously hardening the edge regions of the cutting blade.
US10532485B2 Positioning system
A positioning system, attachable to a vehicle for remote operation of the chain saw by a user sitting in the vehicle. A shock absorber indicator functions to tell the user when the weight on the limb is appropriate to engage the saw, and additionally cushions the drop when the saw cuts through the limb.
US10532479B2 Cutting apparatus
A cutting apparatus for cutting an item supported by a surface, comprising a knife (1) comprising a blade (2), a blade support means (3), and an alignment guide (4), having an arm (7) pivotally attached to the knife and a surface contacting means (8) extending in a direction substantially perpendicular to the longitudinal plane of the knife and adapted to contact the surface in front of the blade, in the cutting direction so that, in use, the alignment guide can move with the blade, as the blade cuts into an item whereby if the knife tilts or tends to tilt, this is resisted by virtue of the alignment guide or, if the resistance is overcome, is reduced by raising of one or other lateral edges of the surface contacting means.
US10532478B2 Power operated rotary knife
A power operated rotary knife including an annular rotary knife blade supported for rotation in a blade housing. The rotary knife blade including a body and a blade section extending from the body. The body includes an outer wall including an arcuate surface having an upper region extending from a first upper end portion to a second intermediate portion and a lower region extending from the second intermediate portion to a third lower end portion. A plurality of gear teeth extend downwardly from the upper end of the body, each of the plurality of gear teeth including an outer peripheral face forming a portion of the upper region of the arcuate surface of the outer wall. The body outer wall includes a bearing surface having a lower bearing face in the lower region of the arcuate surface and an upper hearing face in the upper region of the arcuate surface.
US10532475B2 Grooming system with adaptive lighting and operating method
The present disclosure relates to a grooming system having an adaptive lighting system (70) and a personal care appliance (50), particularly a hair cutting appliance, the adaptive lighting system (70) comprising at least one sensor (74, 76, 78, 80) that is arranged to detect an illumination-indicative value in the vicinity of a treatment head (54) of the appliance (50), at least one light source (72, 110, 134) that is arranged to illuminate a treatment zone, a lighting control unit (86, 102) operatively coupled with the at least one sensor (74, 76, 78, 80) and the at least one light source (72, 110, 134), wherein the lighting control unit (86, 102) is arranged to control the at least one light source (72, 110, 134) dependent on the illumination-indicative value detected by the at least one sensor (74, 76, 78, 80), and wherein the lighting control unit (86, 102) is arranged to increase a target illumination level when a detected actual illumination level is low, and to decrease a target illumination level when a detected actual illumination level is high. The present disclosure further relates to a method of operating an adaptive lighting system (70) and to a corresponding computer program.
US10532474B2 Beard trimmer with one or more rotary heads surrounded by combs having a particular shape and provided with a comb protection position
A beard trimmer may include a handle and a cover, as well as a cutting system with one or more vertical axis rotary cutting heads. The rotary cutting heads may have a moving blade and a fixed blade, each head being surrounded by a crown-shaped comb. The comb may be adjustable in height in order to adjust, in use, the distance between the blades and the skin, and thereby to adapt the cutting of the beard to the desired length. The cover is movably mounted between a closed position and an open position on the handle, such that the cover can be moved from an open position to a protection position where it is flush with the comb tines in order to store the device.
US10532473B2 Electric shaver
The present invention relates to an electric shaver. More particularly, the present invention relates to an electric shaver comprising a handle and a shaver head including at least one cutter unit having a drivable cutter element and a shear foil, wherein the shaver head is connected to the handle by means of a support structure which in some cases may provide for some movability of the shaver head relative to the handle. The shaver head and/or the at least one cutter unit may have an elongated contour with a main axis extending transverse to the handles' longitudinal axis and substantially parallel to a cutting oscillation axis of the cutter element. The shaver head is spaced apart from the handle with a gap defined between a bottom face of the shave head and a top face of the handle, the gap forming a ring-shaped contraction in the outer contour of the shaver around the support structure and giving access to the support structure bridging the gap.
US10532468B2 Manufacturing vacuum tool with selective activation of pickup zones
Systems, methods, and apparatus for a vacuum tool having a switchable plate, such that a common vacuum tool may be adapted with different plates. A switchable plate may form the entirety of the vacuum tool's material contacting surface or a switchable plate may form a portion of the material contacting surface. The vacuum tool is effective for picking and placing one or more manufacturing parts utilizing a vacuum force.
US10532463B2 Protocol for a remotely controlled videoconferencing robot
A robotic system that includes a robot and a remote station. The remote station can generate control commands that are transmitted to the robot through a broadband network. The control commands can be interpreted by the robot to induce action such as robot movement or focusing a robot camera. The robot can generate reporting commands that are transmitted to the remote station through the broadband network. The reporting commands can provide positional feedback or system reports on the robot.
US10532458B2 Robotic manipulator
A manipulator includes a mount member, a base member with threaded openings and an aperture, two links, and an output member with threaded openings and an aperture. The manipulator also includes three motors mounted to the mount member and three drive trains connected to the motors, respectively.
US10532455B1 Ergonomic handle adapted for use with a hand-operated personal use device
An ergonomic handle to be used in conjunction with a hand-operated personal use tool. A unique feature of the ergonomic handle is a series of concave-shaped grooves and convex-shaped protrusions on the top surface and one concave-shaped groove and two convex-shaped protrusions on the bottom surface. The ergonomic handle has an arcuate shape to facilitate a secure grasping of the handle by the fingers of one handle.
US10532454B2 Electric working machine
An electric working machine according to one aspect of the present disclosure includes an output shaft, a motor, a transmitting device, a drive device, a controller, and a current path. The transmitting device has transmittable allowable torque and transmits rotation of the motor to the output shaft. The drive device energizes the motor with electric supply from a battery in accordance with a command from outside the electric working machine. The current path is configured to be able to energize the motor with a current value larger than an allowable current value required to limit torque generated in the transmitting device due to rotation of the motor to the allowable torque or smaller.
US10532453B2 Fastener-driving tool including a reversion trigger with a damper
A fastener-driving tool is provided and includes a housing and a workpiece-contacting element movably connected to the housing, where the workpiece-contacting element is movable between a rest position and an activated position. A trigger is movably connected to the housing such that the trigger is movable between a rest position and an activated position. The tool further includes an actuation lever movably connected to the trigger and movable between a rest position and an activated position. A damper mechanism is associated with the actuation lever and is configured to control a rate of movement of the actuation lever between the activated position and the rest position.
US10532440B2 Fishing pole grip modification system and method of using same
In certain embodiments, a system is provided for the efficient removal of an old grip from a fishing pole while maintaining the integrity of the pole. The system can include a removal portion including one or more rotational assemblies that rotate one or more grinding members. The grinding members can include a rotational blade with a centering rod. The rotational assembly can remove the old grip while maintaining the integrity of the rod within. The system can include multiple sets of grinding members that are organized for efficient identification or may include adjustable grinding members that can be configured for specific rods. The system can further include a guide to help identify particular grinding members for use with particular fishing poles.
US10532438B2 Drilling device and method for adjusting cutting operational parameters during drilling of a multilayer element
A method for drilling an element to be drilled by a drilling device and a cutting tool including drill margins and cutting edges. The method includes determining at least one load value representing overall drag due to internal friction of the drilling device and to friction of drill margins in the element to be drilled. Determining includes: stopping a drilling operation in progress; partial retraction of the cutting tool on a predetermined distance, the predetermined distance being chosen such that the cutting edges are no longer in contact with the element to be drilled; driving the cutting tool with predetermined cutting parameters; measuring at least one load value during the driving of the cutting tool with the cutting parameters before its cutting edges again come into contact with the element to be drilled and after stabilization of the load values, the measured load value representing the overall drag.
US10532434B2 Brazing sheet
In one embodiment, a brazing sheet comprises: a core layer, a braze liner on the first side of the core layer; and a waterside liner on the second side of the core layer. The core layer is comprised of a 3xxx series aluminum alloy. The waterside liner is an aluminum alloy comprising: 7-20 wt % Zn; up to 0.25 wt % Si; up to 0.1 wt % Cu; up to 0.25 wt % Mn; up to 0.1 wt % Mg; and up to 0.1 wt % Cr. In some embodiments, the brazing sheet has a thickness of 60-180 microns. In some embodiments, the waterside liner comprises 1-15% of the thickness of the brazing sheet.
US10532430B2 Laser machining apparatus
A laser machining apparatus has a workpiece holding unit, a laser irradiation unit, a machining feed unit that moves the holding unit and the laser irradiation unit in a machining feed direction, an indexing feed unit that moves the holding unit and the laser irradiation unit in an indexing feed direction, and a control unit that controls the operation of each component. The time required to stop the laser irradiation unit relative to the holding unit can be denoted by ‘ta’ and that required to index the irradiation position of the laser beam at the next scheduled division line can be denoted by ‘tb.’ When tb>ta, the control unit initiates the stopping and indexing simultaneously after a machining step and takes advantage of remaining time (tb−ta) following the end of the stopping to start to accelerate the laser irradiation unit relative to the holding unit.
US10532428B2 Interlocking flexible segments formed from a rigid material
A method for creating a flexible portion or bending portion within a rigid structure. The method can also be used for creating a flexible structure from a rigid material. The method includes providing a substantially rigid material, such as, but not limited to, metals, alloys, hard plastics, and the like, and selectively removing portions of the rigid material defining a geometric pattern in the rigid material. A bending radius of the flexible portion is defined by the geometric pattern. The rigid structure may be used to create an enclosure, a cover for an electronic device, one or more hinges, or the like.
US10532424B2 Device for welding components by means of ultrasound
A device (10′) for welding components by ultrasound. The device (10′) comprises a sonotrode (11′) having a sonotrode head (12′), which can be excited by a vibration generator to produce torsion vibrations with respect to a torsion axis (T). At least one welding surface (14′) is arranged on the peripheral side on the sonotrode head (12′) with respect to the torsion axis (T). The device (10′) also comprises a support device (15′) which supports the sonotrode head (11′) in a support area (16′), which contains a vibration node of the sonotrode head (12′). The support area (16′) and the welding surface (14′) at least partially extend along a common plane (E) which extends perpendicular to the torsion axis (T). A device (10′) for welding components by ultrasound by using a temperature control device are also disclosed.
US10532423B2 Battery pack and method for manufacturing the same
Provided is a battery pack. The battery pack includes a plurality of battery cells, each of which is provided with an electrode tab, an electrode lead including first and second lead parts respectively connected to the electrode tabs of the adjacent battery cells and a connection part connecting the first and second lead parts to each other, and a bus bar to which the first and second lead parts are coupled and connecting the plurality of battery cells to each other in series or parallel.
US10532421B2 UAM resistance spot weld joint transition for multimaterial automotive structures
A vehicle body assembly is described herein, including a first structural component and a second structural component. The first structural component may be a roof component or a side panel, and include a first part including a first metal and a second part including a second metal different than the first metal. The second part is formed on a peripheral edge portion of the first part and defines a mounting flange for the first structural component. The second part is joined to the first part via an ultrasonic additive manufacturing (UAM) interface. The second structural component is including the second metal and is joined to the second part at the mounting flange via a resistance spot weld (RSW) joint.
US10532413B2 Fastening structure, head, and shank
Provided is a fastening structure having a wide application range and a high degree of freedom of design. A fastening structure includes: a head including a first end surface and a first screw part formed on the first end surface; and a shank including a second end surface and a second screw part formed on the second end surface and threadedly engaging with the first screw part. The first end surface includes a first principal surface oriented in an axial direction of the first screw part and a first step surface oriented in a rotational direction of the first screw part. The second end surface includes a second principal surface oriented in an axial direction of the second screw part and a second step surface oriented in a rotational direction of the second screw part. The first and second principal surfaces face each other and the first and second step surfaces face each other when the first screw part threadedly engages with the second screw part.
US10532408B2 Pipe end machining device
A pipe end machining device configured to machine an end of a pipe includes an outer housing, a spindle rotatably mounted within the outer housing and configured to carry tool supports and cutting tools, a mounting assembly configured to be attached to the pipe, a stem extending from the mounting assembly and connected to the spindle by an interengagement which allows the spindle to move linearly relative to the stem, but prevents rotational movement of the spindle relative to the stem, and a locking assembly attached to the stem and configured to fix the vertical position of the outer housing and the spindle relative to the mounting assembly.
US10532405B2 Support posts for improved flexural strength in 3D-printed objects
Techniques for improving flexural strength in 3D-printed object. The techniques generally include identifying a portion of a 3D model corresponding to the 3D-printed object to which one or more support posts should be added and adding support post descriptors to the 3D model within such a portion. The support post descriptor defines a position and at least one dimension of a support post cavity and a position and at least one dimension of a support post, both having a height corresponding to at least two layers of 3D-printable material. The model, including the support post descriptors are transmitted to a 3D printer to print the 3D model, which includes a support post cavity and a support post having a height of at least two layers.
US10532404B2 Powder material packing method
In molding a compact having portions of an equal thickness on opposite sides of a through-hole, an advancing speed of a holder holding a powder material is adjusted before the holder is advanced and retracted over a die cavity of a die. Specifically, a first preparation of determining in advance a relation between the advancing speed of the holder and a packing density of the powder material packed in the die cavity at each of the portions to be of an equal thickness of the compact on opposite sides of the through-hole is made; and, based on the relation determined in the first preparation, the advancing speed of the holder is adjusted to a speed at which the packing density becomes uniform. Thus, the packing density of the powder material packed in the die cavity can be uniformized, so that the dimensional accuracy of the molded compact can be improved.
US10532399B2 Machine for continuous casting of a lead alloy for forming a continuous strip of grids for plates of electric storage batteries
Machine for continuous casting of a lead alloy for forming grids for plates of electric storage batteries, which comprises a rotary drum having an external peripheral surface with a plurality of grooves obtained according to the grid design to be made and a sliding block coupled in sliding relation with the external surface of the rotary drum and with a distribution duct obtained in order to insert the molten lead in the plurality of grooves. The plurality of grooves comprises circumferential notches and transverse notches that meet in respective vertices. At the vertices and within the circumferential notches, a plurality of studs are placed that are intended to shape corresponding corners of smoothed form of the grids.
US10532398B2 Enclosure having a sealing device for a casting installation
An enclosure having a sealing device, for a casting installation, having a first body and a second body that is removably joined to the first body along a bearing axis, the first and second bodies together delimiting an internal chamber. The sealing device comprises: at least one compression member, at least one seal having a lateral contact face extending substantially parallel to the bearing axis; the compression member and the seal being arranged with respect to one another such that the compression member is in contact with the lateral contact face of the seal and exerts a compression force thereon that is oriented orthogonally to the bearing axis.
US10532397B2 Method and system for producing sand moulds
The method for the stepwise production and advancing of sand mold parts in a mold-string foundry plant comprising a station (1) for making mold parts, a pouring station (3) and a conveyor (2) for stepwise advancing of mold parts (101-109) from said station (1) for making mold parts towards said pouring station (3), includes the step of double indexing the mold parts using a first, moveable, part (21) of the conveyor. By double indexing the mold string, the time during which pouring into the molds has to be interrupted can be reduced.
US10532386B2 Continuous-cast slab, method and apparatus of manufacturing the same, and method and apparatus of manufacturing thick steel plate
A continuous-cast slab is provided where central porosity is reduced by surly crushing the slab. A method and apparatus of manufacturing the slab is also provided. The continuous-cast slab having horizontally symmetrical granular equiaxed crystals at least in the center in the thickness direction includes a first reduction dent and a second reduction dent that further dents from the bottom surface of the first reduction dent and is narrower than the first reduction dent at least on one long side surface. Such a configuration can makes it possible to achieve the continuous-cast slab of no more than 2.5×10−4 cm3/g in a maximum porosity volume while segregation is reduced.
US10532385B2 Disposal of medicaments
Composition to aid in the sequestration and/or disposal of unused human or animal pharmaceutical drug or medication. The composition comprises a disposal composition material that contains a gelling or massing agent and optionally other components, and can be in the form of pellets, beads, beadlets, granules, or the like. The disposal composition material can be incorporated into a sachet or other disposal container or its cap to prevent the use of the medicament or the removal/extraction of active agent(s) from a pharmaceutical dosage form intended for disposal, to an appreciable extent and/or rate. With in the disposal agent, or fill material there may also be additional ingredients to promote mixing, sequestration or destruction of the active agent. The disposal composition is contained in a sachet and dispensed with a medicament for use when the patient has finished with the medication and there is material left over for disposal. In addition, the sachet could be made available for use with non-prescription drugs and other materials.
US10532384B2 Shutdown system for metal-air batteries and methods of use thereof
This invention provides systems and methods for treating electrodes used in batteries and electrochemical cells upon battery/cell shutdown and prior to battery standby mode. Systems and methods of this invention are directed toward the use of aerosol to treat the electrode and to protect the electrode and/or the environment from undesired reactions.
US10532383B2 Method of producing three-dimensional object and removing liquid to be used in the production method
Provided is a method of producing a three-dimensional object, including: a first step of placing and laminating a water-insoluble structural material and a support material each containing a water-soluble material and a fiber material to form a material layer; and a second step of bringing a portion of the shaped object including the support material into contact with a liquid containing water and a bipolar surfactant to remove the portion.
US10532380B2 Making an ore separation wheel
A method of making a circular ore separation wheel, for concentration critical stategic rare earths, and preciouse metals, such as gold. The method comprising: 1) forming a base section of the circular ore separation wheel using 3D printing; 2) forming a central hole in the base section being centrally located in the circular ore separation wheel; 3) forming a plurality of teeth, using 3D printing, upon the base section, having a inner end proximate to the central hole and extending therefrom in a circularly radiating direction and having an outer end opposite the inner end with different sizes on the same length of tooth, 4) forming a plurality of micro grooves from about 4.5-0.001 mm partially along outer surfaces of the plurality of teeth extending in a direction from the inner end to the outer end of the plurality of teeth, wherein the plurality of micro grooves are formed by the 3D printing process leaving a small gap located between subsequent extruded layers at the outer surface of the plurality of teeth; and 5) forming a circumferential wall around the ore separation wheel that is proximate to the outer end of the plurality of teeth, and is proximate to the base section. And potentially manufacturing the circular ore separation wheel inside of a pre-made support section with the desired internal concave contours.
US10532377B2 Mask assembly for thin film deposition
A mask assembly for thin film deposition includes: a mask frame including an opening, the mask frame disposed surrounding the opening; and a mask unit including: first masks mounted on the mask frame, the first masks extending in a first direction; a second mask disposed on the first masks, the second mask including: one open hole; and at least one foreign substance discharge hole; and a third mask disposed on the second mask, the third mask extending in a second direction and including deposition holes, wherein the second direction crosses the first direction, and wherein a substrate is disposed on the third mask.
US10532374B2 Thin film production method and organic el device production method
A thin film production method according to one embodiment includes: a coating film forming step of forming a coating film by discharging a coating liquid on a support from first to M-th line heads (M is 2 or larger and N or smaller) while allowing the support to pass through N line heads once; and a drying step of obtaining a thin film by drying the coating film. A thin film forming nozzle hole 28 of the m-th line head (m is 2 or larger and M or smaller) is arranged to be positioned between adjacent thin film forming nozzle holes in an (m−1)-th thin film forming nozzle hole array Qm-1. Every time the first line head discharges the coating liquid, the m-th line head applies the coating liquid onto the support at a predetermined delay time with respect to a discharge time of the first line head. The first to M-th line heads discharge the coating liquid from the film forming nozzle hole selected in accordance with a shape of a thin film formation region onto the support.
US10532371B2 Dispensing assemblies and related methods
A dispensing assembly for dispensing fluid generally includes a container having a handle located toward an upper portion of the container, and a sprayer having arms extending away from the sprayer. The arms of the sprayer define a channel configured to receive at least part of the handle of the container within the channel to thereby couple the sprayer to the container. Such a dispensing assembly can be made by forming the container with a handle located toward an upper portion of the container, and forming the sprayer with the arms such that the arms can be used to couple the sprayer to the handle of the container, where the arms extend away from the sprayer and define the channel for receiving at least part of the handle of the container into the channel.
US10532364B1 Electrostatic precipitator module and desulfurization system including the same
An electrostatic precipitator module and a desulfurization system are capable of easily discharging wash water from a wet electrostatic precipitator module. The electrostatic precipitator module includes an arrangement of discharge electrodes and collecting electrodes alternately disposed and spaced apart from each other, the discharge electrodes configured to be charged to a predetermined voltage for generating a corona discharge between the discharge electrodes and the collecting electrodes; and tie rods for fixing the discharge electrodes and the collecting electrodes. Each collecting electrode has a lower edge inclined downward with respect to the ground. The lower edge of each collecting electrode includes separate lower edge portions respectively inclined downward from opposite side ends of the collecting electrode and a lowermost point at which wash water is concentrated and discharged to a discharge guide installed directly under the lowermost points. The discharge guide has a width substantially smaller than the collecting electrode.
US10532362B2 Static plant for preparing feed mixes for ruminant livestock
Static plant for preparing feed mixes for ruminant livestock, having a conveyor unit for conveying the feed mix ingredients, chain and/or screw feeders, feeders with weight sensors and supplementary conveyor belt, silos of solid ingredients, and silos of liquid ingredients, independently supplying via the conveyor unit, with dual flow, two or more high-capacity mixers.
US10532354B2 Multicompartment layered and stackable microfluidic bioreactors and applications of same
In certain aspects of the invention, a stackable device includes multiple elements stacked sequentially. A chamber is formed in each of the elements or between adjacent two of the elements, and each chamber is in fluid communication with an input channel and an output channel. The chambers are aligned with each other, and adjacent two chambers are separated from each other by a membrane. In certain aspects of the invention, a system includes at least one stackable device, each stackable device having multiple chambers; and at least one of a perfusion controller, a microformulator, and a microclinical analyzer in fluid communication with the at least one stackable device. In other aspects of the invention, the use of four microformulators, electrodes and an impedance analyzer can measure the impedance spectrum of each barrier in a multi-transwell plate.
US10532352B2 Sample analysis system
An integrated sample analysis system is disclosed. The sample analysis system contains (1) a sample preparation/analysis module having sample purification device comprising a monolith that binds specifically to nucleic acids and a sample analysis device comprising a microarray enclosed in a reaction chamber having a hydrophilic interior surface; (2) a temperature control module comprising a thermocycler having a thermally conductive temperature-control bladder; and (3) an imaging device capable of capturing an image of the microarray in the reaction chamber.
US10532346B2 Method for producing a metal-supported catalyst and catalyst substrate
The present invention relates to methods for producing metal-supported thin layer skeletal catalyst structures, to methods for producing catalyst support structures without separately applying an intermediate washcoat layer, and to novel catalyst compositions produced by these methods. Catalyst precursors may be interdiffused with the underlying metal support then activated to create catalytically active skeletal alloy surfaces. The resulting metal-anchored skeletal layers provide increased conversion per geometric area compared to conversions from other types of supported alloy catalysts of similar bulk compositions, and provide resistance to activity loss when used under severe on-stream conditions. Particular compositions of the metal-supported skeletal catalyst alloy structures can be used for conventional steam methane reforming to produce syngas from natural gas and steam, for hydrodeoxygenation of pyrolysis bio-oils, and for other metal-catalyzed reactions inter alia.
US10532341B2 Particulate water absorbing agent
A particulate water absorbing agent having a polyacrylic acid (salt)-based water-absorbing resin as a main component, being surface-crosslinked and satisfying physical properties (1) to (3) below: (1) a proportion of particles with a particle diameter of not less than 150 μm and less than 850 μm is not less than 90% by weight; (2) an elastic modulus index (EMI) of particles with a particle diameter of not less than 500 μm and less than 600 μm is not less than 5500; and (3) a recovery rate defined as Rec.CRC/CRC is 1.05 to 1.20, the particulate water absorbing agent being particularly useful for absorbent articles.
US10532339B2 Compositions and methods for calcining diatomaceous earth with reduced cristobalite and/or reduced beer soluble iron
A method for calcining diatomaceous earth may include adding at least one lattice interfering agent to the diatomaceous earth to form a composite material. The method may further include heating the composite material at a temperature of at least about 800° C. for at least about 15 minutes to form an at least partially calcined composite material. The at least one lattice interfering agent may include at least one cation of at least one of aluminum and titanium. A diatomaceous earth product may include the at least partially calcined composite material formed from the above-noted method for calcining diatomaceous earth. A filter aid may include the diatomaceous earth product.
US10532338B2 Shell and tube oxidation reactor with improved resistance to fouling
The present disclosure relates to a single shell open interstage reactor (“SSOI”). The SSOI comprises a first reaction stage, an interstage heat exchanger, an open interstage region, and a second reaction stage. The SSOI may be configured for upflow or downflow operation. Further, the open interstage region of the SSOI may comprise a supplemental oxidant feed. When the open interstage region comprises a supplemental oxidant feed, the SSOI may further comprise a supplemental oxidant mixing assembly. Processes for producing acrylic acid through the oxidation of propylene are also disclosed.
US10532336B2 System for analysis and reuse of waste liquids
A system for measurement of quantity (density) of particles/solid materials in wastewater, and dilution of particle quantity based on the intended application. Currently enabling quick and serial measurement of particle quantity in laboratory environment, this system is placed inside the desired step of the process of an industrial facility. This way, the system yields quick results and in turn reduces the analysis and evaluation costs.
US10532335B1 Hair colorant dispensing system
There is disclosed a system for enabling dynamic mixture of hair colorant for individuals within a local retail establishment or salon. The system utilizes a dynamically-updatable database of hair colorant mixtures, based upon input data regarding natural hair color and current state to generate a suitable mixture. The same system and database can be used for subsequent refill orders from a remote manufacturing site. The remote manufacturing system operates in much the same way, but at a larger scale, and can be used for subsequent refill orders submitted online. Whichever system is used, the same user and colorant mixtures will be generated, and any updates or changes to the colorant mixture will appear on any system reliant upon the same database of colorant combinate instructions.
US10532328B2 Polyaniline-based chlorine resistant hydrophilic filtration membranes
In one aspect, the invention relates to chlorine-resistant filtration membranes comprising n-alkyl substituted polyaniline derivatives for use in, for example, water purification, and methods for making and using same. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
US10532325B2 Capillary pressure re-set mechanism and applications
Many hand-held diagnostics are limited in their functionality due to the challenging physics associated with small dimensional systems. An example of this is capillary forces in hydrophilic systems, such as the tight retention of liquid passing through a small pore filtration membrane, or capillary force driven microfluidics where, to keep liquid flowing the dimensions of the system become so small that the flow rates are too low to be useful, or the manufacturing of such devices becomes uneconomical. This disclosure details methods to ‘reset’ the capillary force condition to avoid the requirement of transient pressure spikes associated with the breakthrough pressure of small pore membranes, and avoid the necessity of extremely small microfluidic channels, which can be useful in applications such as filtration of whole blood to plasma using only suction pressure or passive capillary pressure.
US10532324B1 Instruments, modules, and methods for improved detection of edited sequences in live cells
The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
US10532318B2 Method and system for applying superimposed time-varying frequency electromagnetic wave for marine ballast water bio-fouling control
The disclosure relates to a method and system for treating ballast water and ballast water treatment systems in order for treatment effects to be carried out, such as controlling the transportation of undesirable and invasive marine organisms. In particular, the disclosure relates to methods and systems for applying a superimposed time-varying frequency electromagnetic wave comprising both AC and DC components in a pulsating manner to ballast water within a ballast water treatment system.
US10532317B2 Removal of metals from CO2 capture solvents
Corrosion in a CO2 removal system is reduced or even entirely avoided by use of a metal ion chelator unit that removes metal ions, and especially iron ions from an amine solvent to a level of equal or less than 1 mg/l without substantially binding heat stable salts.
US10532313B2 Activation of a material containing alkaline-earth metal carbonate and alkaline-earth metal hydroxide for the dry scrubbing of flue gas
The invention relates to a method for increasing the absorbency of a material containing alkaline-earth carbonate and alkaline-earth hydroxide with regard to sulfur oxides and/or other pollutants, in particular in flue gas, wherein the material containing alkaline-earth carbonate and alkaline-earth hydroxide is activated by heating said material to approximately 250° C. to approximately 750° C. for a time period of 1 minute to 12 hours.
US10532312B2 Exhaust gas processing system and processing method
An exhaust gas processing system having excellent durability and good desulfurization and denitration efficiency is provided to efficiently recover carbon dioxide with high purity and reduced processing costs. The exhaust gas processing system has: a desulfurization unit removing sulfur oxides from the exhaust gas by the limestone-gypsum method; a denitration unit arranged downstream of the desulfurization unit to remove nitrogen oxides from the exhaust gas; a carbon dioxide recovery arranged downstream of the denitration unit to recover carbon dioxide from the exhaust gas; and an oxygen supply unit supplying to the desulfurization unit with a faction of the recovered gas from the carbon dioxide recovery unit as oxygen source. An analyzer is used to monitor the purity and recovery ratio of the carbon dioxide recovered, and the supplied ratio of recovered gas is adjusted, based on the monitored purity and recovery ratio.
US10532306B2 Frame-type air purifier with changeable imaging sheet
A frame-type air purifier includes a purifier housing, a main frame and an image board. The purifier housing has a back plate and a front plate configured opposite to each other. The back plate has a wall positioner configured thereon. The front plate includes a first quick-demounting member configured thereon. The main frame has a central hollow and a second quick-demounting member configured thereon. The image board includes a baseboard and an imaging sheet configured on the baseboard, wherein the baseboard has a third quick-demounting member configured thereon. The first quick-demounting member of the purifier housing selectively assembles with the second quick-demounting member of the main frame correspondingly, or selectively assembles with the third quick-demounting member of the image board correspondingly.
US10532298B2 Method for separating solid particles from a waterbody
The present disclosure relates to a method for separation of solid particles from a waterbody. Preferably, the present disclosure relates to a method, wherein a combination of chemicals including coagulant(s) and flocculant(s) are employed for said separation of solid particles, wherein suitable examples of solid particles are living organisms and non-living matter, wherein living organisms include autotrophs such as phototrophs, which are either microscopic or macroscopic in nature (algae). The disclosure thus particularly relates to method of chemical coagulation and flocculation for separating solid particles, preferably either algae or bacteria or both from a waterbody. The present disclosure also provides for an alternate method, wherein the aforesaid method of coagulation and flocculation is combined with electro-coagulation and/or pH modulation strategies for separation of said solid particles in any sequence.
US10532292B2 Thin-film treatment apparatus
A thin-film treatment apparatus for treating viscous material, including a housing, having a heatable and/or coolable housing casing, which encloses a rotationally symmetric treatment chamber extending in the axial direction, an inlet port, arranged in an inlet region of the housing, for feeding the material to be treated into the treatment chamber, an outlet port, arranged in an outlet region of the housings, for discharging the material from the treatment chamber, and a coaxially extending, drivable rotor shaft, arranged in the treatment chamber, for producing a material film on the inner face of the housing casing and for conveying the material in the direction from the inlet region toward the outlet region, the rotor shaft including a central rotor shaft body and rotor blades arranged on the circumference thereof, the radially outermost end of which rotor blades is distanced from the inner face of the housing casing.
US10532285B2 Communication system, method for controlling communication system, and program
In a communication system including a server and a plurality of communication terminals capable of communication with the server, based on a variety of parameters indicating the status of a space formed within a game playable by the user of each communication terminal over the communication system, the server transmits advisory information, which suggests the next action for the space, to the communication terminal. The communication terminal displays a screen including the received advisory information.
US10532280B2 Game system, and storage medium
Provided is a game system that is capable of suppressing time needed to share or exchange opinions between users in a game. This game system provides a quiz game that is played by eight users simultaneously. Furthermore, in a information share phase of the quiz game, the game system gives, via a game screen for selecting a region, a selection opportunity that is shared by the eight users such that eight selected regions corresponding to the eight users are selected individually by them from three region images of an enemy character image, and provides, in there, selection status information relating to the eight selected regions. Then, in a battle phase which follows the information share phase, the game system gives, based on the selection result in the information share phase, changes corresponding to the eight selected regions to the quiz game such that user characters attack the selected regions.
US10532277B2 Hand-held controllers with light-emitting diodes synchronized to an external camera
A hand-held controller for a virtual-reality system includes an antenna, a grip, a cage coupled to the grip, and a plurality of LEDs on an outer surface of the cage. Wireless signals are received from a remote camera via the antenna. The plurality of LEDs is duty-cycled, which includes turning on the plurality of LEDs at times determined using the wireless signals. The times when the plurality of LEDs is turned on correspond to times when the remote camera captures images of the hand-held controller.
US10532271B2 Data processing method for reactive augmented reality card game and reactive augmented reality card game play device, by checking collision between virtual objects
The present invention relates to a data processing method for a reactive augmented reality card game and a reactive augmented reality card game play device and, more particularly, to a data processing method for a reactive augmented reality card game and a reactive augmented reality card game play device, by checking collision between virtual objects, in which preconfigured animation data is processed and reproduced by checking collision between virtual objects.
US10532268B2 Smart device
An Internet of Thing (IoT) device includes a camera coupled to a processor; and a wireless transceiver coupled to the processor. Blockchain smart contracts can be used with the device to facilitate secure operation.
US10532266B2 Electronic wearable interactive sports play communication system
Embodiments disclosed herein include methods and systems for communicating plays or other messages between a coach or other non-player user and a player user during a live sporting event or training session. The system includes a set of wearable devices that are worn by players during a sporting event and a computing node that can be used by the coach to select plays or actions. The plays or other actions selected by the coach can be disseminated to the set of wearable devices enabling one or more players to quickly and accurately determine the play or action to perform.
US10532265B2 System for sensor-based objective determination
The present disclosure is directed to a system for sensor-based objective determination. In general, sensor data may be used to render objective determinations that were not previously possible due to the unavoidable subjectivity of human-based officiating systems. For example, at least one device may be configured to make objective determinations during the course of a sporting event. Data collection circuitry may receive data from sensor devices coupled to players, equipment, playing surfaces, etc. Data analysis circuitry may categorize the data and input the data into a model to determine if an infraction occurred. For example, categorization may involve determining a type of infraction that may have occurred based on the sensor data. The model may then be selected based on the type of infraction, the model being developed utilizing prior sensor data, rules for the sporting event, etc. Output circuitry may generate a notification based on the infraction determination.
US10532262B2 Telescoping football holder
A compact device for assisting place kicking a football is disclosed, including a module connecting telescoping legs and football tip telescoping holding arm, with the legs connecting the module for pivoting the legs from a ground engaging position to a transport position beneath and parallel to the arm.
US10532256B2 Golf club head
A golf club head comprises a sole, a recessed sole port in the sole; and a rotatably adjustable sole piece adapted to be at least partially received within the sole port and comprising a central body having a plurality of contact surfaces adapted to contact the sole port and being offset from each other along a central axis extending through the central body of the sole piece. The sole piece can be positioned at least partially within the sole port at five or more rotational and axial positions with respect to the central axis, wherein at each rotational position, at least one of said contact surfaces of the central body contacts the sole port to set the axial position of the sole piece. The sole port and/or the sole piece can be generally pentagonal in shape.
US10532252B2 Dimple patterns for golf balls
The present invention provides a method for arranging dimples on a golf ball surface in which the dimples are arranged in a pattern derived from at least one irregular domain generated from a regular or non-regular polyhedron. The method includes choosing control points of a polyhedron, generating an irregular domain based on those control points, packing the irregular domain with dimples, and tessellating the irregular domain to cover the surface of the golf ball. The control points include the center of a polyhedral face, a vertex of the polyhedron, a midpoint or other point on an edge of the polyhedron and others. The method ensures that the symmetry of the underlying polyhedron is preserved while minimizing or eliminating great circles due to parting lines.
US10532250B2 Curvilinear golf ball dimples and methods of making same
The present invention is directed to golf balls having surface textures with unique appearances and improved aerodynamic characteristics due, at least in part, to the use of curvilinear dimple plan shapes. In particular, the present invention is directed to a golf ball that includes at least a portion of its dimples having a plan shape defined by a number of convex or concave arcs that are derived from the vertices of a regular n-sided polygon, for example, an equilateral triangle or square.
US10532247B2 Exercise device
An exercise device. The exercise device includes a housing having a pair of sidewalls, wherein a rear end of the pair of sidewalls has a greater height than a front end thereof, such that the housing includes an angled upper side. A belt is disposed within the housing and is connected to a motor such that the belt can rotate within the housing. A plurality of steps are affixed to the belt such that the plurality of steps extend through the angled upper side of the housing to create a staircase effect. A pair of rails extend from an upper end of each of the pair of sidewalls to form handrails for gripping purposes. An arm is pivotably connected to one of the rails such that the arm is dampened by pneumatic pressure about the pivot point.
US10532240B2 Resistance training device and method
A method for use with a physical training device is provided. The device including an elastic resistance strap having first and second handles. The method includes pulling at least one of the first and second handles to generate force on a target muscle group through resistance training. The method also includes pulling the at least one of the first and second handles to generate anaerobic and aerobic muscle activity within the target muscle group through cardiovascular interval training.
US10532239B1 Apparatus for exercising
An apparatus for exercising having a frame assembly defining a triangular prism shape, which has a frame top bar that has connected a first set of frame lateral bars and a second set of frame lateral bars. The frame assembly further has first and second frame base bars and first and second frame lateral base bars. First and second clamp assemblies are mounted onto the frame top bar. The apparatus for exercising further has first and second band assemblies, a strap assembly, first and second upper handle assemblies, and a board assembly, which are removable from the frame assembly. The frame assembly is used for exercising alone and/or in conjunction with the first and second band assemblies, the strap assembly, the first and second upper handle assemblies, and the board assembly.
US10532236B2 Method of fire protection for storage occupancies utilizing a plurality of pendent control mode specific application extended coverage fire protection sprinklers
A fire protection method includes providing a plurality of pendent control mode specific application extended coverage fire protection sprinklers as components of a fire protection sprinkler system for a storage area defined by a storage height of at least 25 feet and a building height of at least 30 feet. Each sprinkler has a thermally responsive element, a deflector, and a K-factor of at least 25.2 gpm/(psi)1/2, and is connected to a piping network at a height greater than the storage height. When each sprinkler is activated, a fluid is supplied to the sprinkler from the piping network at a pressure of at least 30 pounds per square inch, and is delivered to a coverage area of greater than 110 and up to and including 196 square feet per sprinkler. A design operating area of the sprinkler system is up to six sprinklers or 1200 square feet.
US10532235B2 Grid mesh anchor
The present invention concerns an anchor assembly for providing a secure point of attachment at a grid mesh platform. The anchor assembly comprises a housing in the form of an elongated case with a central hollow channel, generally rectangular in shape with a flat base and roof. The base includes openings in the form of access slots to provide access from the channel to the exterior of the base. The anchor assembly also comprises a suspension member located within the channel. In operation the anchor assembly spans adjacent structural members underlying the mesh grid. A coupling member in the form of a sling having an end loop is engaged by the suspension member which passes through the end loop of the sling. The sling also passes through one of the slots in the base of the elongated case. An opposite end of the sling provides an anchor point.
US10532233B2 Head simulator for testing respirators
A head simulator, for testing respirators, has a head simulator body (2) with a simulated oral aperture (6) and with a simulated oral cavity (4), which is located behind the simulated oral aperture (6) in the head simulator body. A loudspeaker (8) is arranged in the simulated oral cavity (4). An audio unit (20) is connected to the loudspeaker (8) for reproducing speech via the loudspeaker (8). The head simulator includes a simulated trachea (10), which is in connection with the simulated oral cavity (4) and opens into the simulated oral aperture (6). An air delivery device (30) is provided, which can be operated to allow air to flow through the simulated trachea (10) and the simulated oral aperture (6).
US10532231B2 Hair care composition comprised of bio-modified natural surfactants and cationic molecular network
Natural haircare ingredient composition and haircare compositions containing such natural haircare ingredient compositions are provided. In one novel aspect, the natural hair ingredient composition is provided which comprises candida Krusei mediated bio-modification of marine organism and plants including bio-modified natural marine surfactants, three-dimensional molecular framework, and natural mineral salts. In one embodiment, the natural surfactants are produced from natural marine organisms such as brown algae, sea kelp, sponge, brown seaweeds, and red seaweeds by candida Krusei mediated bio-modification. In another novel aspect, a haircare composition comprises about 10% of the natural haircare ingredient composition, by weight of the haircare composition. In one novel aspect, Candida Krusei bio-modification process is used. Natural polymeric compounds in the marine plants are modified during the process resulting in three-dimensional molecular framework.
US10532230B2 Methods for face and neck lifts
Methods for treating skin and subcutaneous tissue with energy such as ultrasound energy are disclosed. In various embodiments, ultrasound energy is applied at a region of interest to affect tissue by cutting, ablating, micro-ablating, coagulating, or otherwise affecting the subcutaneous tissue to conduct numerous procedures that are traditionally done invasively in a non-invasive manner. Methods of lifting sagging tissue on a face and/or neck are described.
US10532228B2 Multi-color charged particle detector apparatus and method of use thereof
The invention comprises a method and apparatus for using a multi-layer multi-color scintillation based detector element to image a tumor of a patient using a process of determining residual energies of positively charged particles after passing through the patient, the process comprising the steps of: (1) transmitting the positively charged particles at known energies through the patient and into a multi-layer detector element; (2) detecting first and second secondary photons, resultant from passage of the positively charged particles, respectively from a first layer of a first scintillation material and a second layer of a second scintillation material at two respective layer depths, where the first wavelength range differs from the second wavelength range; (4) determining residual energies of the positively charged particles, using output from the step of detecting; and (5) relating the residual energies to body densities to generate an image.
US10532225B2 Tumor surface dose enhancing radiotherapy apparatus using magnetic field
Disclosed is a tumor surface dose enhancing radiotherapy apparatus using a magnetic field, including a radiation beam generating unit that irradiates a radiation beam towards a tumor of a patient, a magnetic field generating unit that forms a magnetic field that is parallel to the radiation beam between the radiation beam generating unit and the tumor of the patient, and a control unit that controls a surface dose of the tumor by adjusting an intensity and an effective area of the magnetic field of the magnetic field generating unit.
US10532223B2 Monochromatic X-ray imaging systems and methods
According to some aspects, a carrier configured for use with a broadband x-ray source comprising an electron source and a primary target arranged to receive electrons from the electron source to produce broadband x-ray radiation in response to electrons impinging on the primary target is provided. The carrier comprising a housing configured to be removeably coupled to the broadband x-ray source and configured to accommodate a secondary target capable of producing monochromatic x-ray radiation in response to incident broadband x-ray radiation, the housing comprising a transmissive portion configured to allow broadband x-ray radiation to be transmitted to the secondary target when present, and a blocking portion configured to absorb broadband x-ray radiation.
US10532221B2 Method of noninvasive treatment of diabetic retinopathy
A method for noninvasive treatment of diabetic retinopathy helps prevent and reverses diabetic retinopathy and other vascular retinopathies, such as diabetic macular edema for a patient. The method comprises administering at least 80 percent pure oxygen to a patient in an oxygen chamber or nasal cannula. The oxygen chamber includes light emitting diodes that emit a light having a wavelength between 630-700 nm wavelengths on the patient. The method also includes administering an anti-inflammatory agent; an anti-oxidant; at least one of the following: an amino acid, arginine, and citrulline; and an omega-3 fatty acids to the patient. In extreme cases of diabetic retinopathy, a cold laser therapy is also administered to the patient with a wavelength between 570 nanometers and 1000 nanometers. The combination of all the aforementioned treatment modalities and compositions that work to synergistically to achieve unexpected clinical results for prevention and reversal of diabetic retinopathy.
US10532219B2 Apparatus for treatment of wounds and skin medical conditions at a predetermined skin area of a human body
An apparatus for treatment of fungal infections and/or other foot skin disorders, comprises a shoe-type housing having a substantially hollow interior forming a treatment chamber, a supporting platform disposed within the hollow chamber; so that a foot of a patient positioned within the treatment chamber is supported by the platform, so that nails are disposed at the lower level of the front part of the chamber, whereas the heel of the foot is being elevated a rear part thereof. A delivery and control assembly for the aqueous solution is provided. At least one light delivery arrangement is disposed within or in the vicinity of the treatment chamber.
US10532215B2 Implantable neurostimulator having power control and thermal regulation and methods of use
Leadless, implantable microstimulators for treating chronic inflammation. These devices can include a static magnetic field detector (e.g., non-Hall effect sensors/detectors, including those based on a Wiegand effect or generating pulses at a predetermined frequency range and using a detection circuit to determine the decay rate of the pulses), to trigger an emergency shut off of the microstimulator. Also described are methods and apparatuses for regulating the temperature of an implant based applied power from a charger (e.g., voltage across the charger when unloaded and when loaded by the implant) to yield a power control loop correlated with the power drawn by the implant to determine temperature of the implant. A negotiation protocol can exchange data between the charger and the implant (e.g., type of charger, type of implant, nature of the coupling between the two, etc.) to set target power control loop parameters to estimate and regulate implant temperature.
US10532214B2 Implantable device header and method
Systems and methods for implantable medical devices and headers are described. In an example, an implantable medical device includes a device container including an electronic module within the device container. A modular header core includes a header core module including at least one bore hole configured to receive a lead, an antenna attachment module coupled to the header core, and an antenna engaged with the antenna attachment module. The antenna attachment module is configured to locate the antenna in a selected position with respect to the header core module.
US10532212B2 Atrial tracking in an intracardiac ventricular pacemaker
An intracardiac ventricular pacemaker is configured to detect a ventricular diastolic event from a motion signal received by a pacemaker control circuit from a motion sensor. The control circuit starts an atrial refractory period having an expiration time set based on a time of the detection of the ventricular diastolic event. The control circuit detects an atrial systolic event from the motion signal after expiration of the atrial refractory period and controls a pulse generator of the pacemaker to deliver a pacing pulse to a ventricle of a patient's heart at a first atrioventricular pacing time interval after the atrial systolic event detection.
US10532208B2 Miniature implantable neurostimulator system for sciatic nerves and their branches
This application describes a miniature implantable neurostimulator system for sciatic nerves and their branches. The implanted miniature neurostimulator is implanted in the leg and stimulates these nerves for the treatment of urinary or bowel incontinence. The miniature implantable neurostimulator has a low duty cycle permitting a small size with medically-acceptable longevity. The system includes a wireless programmer and patient-activated key fob.
US10532205B2 Lead fixation accessory, lead stabilization tool, and related procedures
A lead fixation accessory configured to be positioned over a skull hole and to transition between an opened state and a closed state during a lead implant procedure protects against lead migration by providing a mechanism for securing the lead in place at the skull hole while a stylet is removed from the lead. The lead fixation accessory remains in place after the implant procedure to provide chronic lead stability. A lead stabilization tool configured to access and grip a lead through a slotted cannula during the lead implant procedure also protects against lead migration by providing a mechanism for securing the lead in place at a point where the lead exits the skull hole while the slotted cannula is removed from the skull hole and peeled away from the lead.
US10532204B2 Electrical treatment of hydrocephalus
A method for treating hydrocephalus is provided, including disposing midplane treatment electrodes over a superior sagittal sinus of a brain, outside and in electrical contact with a skull of a head of a subject identified as suffering from hydrocephalus, and disposing lateral treatment electrodes between 1 and 12 cm of a sagittal midplane of the skull. The subject is treated by electroosmotically driving cerebrospinal fluid (CSF) out of a ventricular system of the brain via a subarachnoid space of the brain to the superior sagittal sinus, by activating control circuitry to apply one or more treatment currents between (a) one or more of the midplane treatment electrodes and (b) one or more of the lateral treatment electrodes. Other embodiments are also described.
US10532202B2 Methods and devices for cellular activation
An apparatus includes multiple first reservoirs and multiple second reservoirs joined with a substrate. Selected ones of the multiple first reservoirs include a reducing agent, and first reservoir surfaces of selected ones of the multiple first reservoirs are proximate to a first substrate surface. Selected ones of the multiple second reservoirs include an oxidizing agent, and second reservoir surfaces of selected ones of the multiple second reservoirs are proximate to the first substrate surface.
US10532201B2 Drug administration device, and manufacturing method for drug administration device
A drug administration device includes a substrate having a first surface, a projection extending from the first surface, and a solid drug. One direction that intersects with the first surface is a first direction, and one direction that extends along the first surface is a second direction. A groove serving as a receiving section is formed in the projection. The groove defines a cavity recessed in the first direction toward the substrate and extends in the second direction to open to a section of the peripheral surface of the projection. The drug is received in the groove.
US10532200B2 Micropenetrator device for penetrating a biological barrier
A device that may be placed on a biological barrier can be used to perforate the biological barrier for a variety of purposes such as cosmetic, scar treatment or for the delivery of active agents. A flexible substrate has a first side and a second opposing side and a plurality of micro-penetrator arrangements each comprising a head and a first and second projection, for penetrating a biological barrier, extending from the head. The first and second projection at least partially extend through the flexible substrate towards the first side. The head comprises an elongate arm for spacing apart the first and second projections. A force is applied to the second side causing flexing of the flexible substrate and pushing the projections into communication with a biological barrier.
US10532198B2 Methods for making precision applicators
A method for forming an applicator comprises steps of: creating a digital geometric representation of the structure, the target structure having a flatness ratio; forming the applicator using the digital geometric representation of the target structure, the applicator having a target structure contacting surface; and disposing an active agent upon the target structure contacting surface of the applicator.
US10532196B2 Stent trimming devices and methods
Devices and methods for trimming a stent to a desired length with an outer tube and an inner tube having a distal end and a diameter configured to receive a portion of the stent in excess of the desired length. The inner tube may move within the outer tube and the distal end may include an end effector configured to trim the portion from the stent while the device and stent are within a patient.
US10532195B2 Systems and methods for the conditioning of cerebrospinal fluid
Systems and methods for treating biologic fluids are disclosed. Some disclosed embodiments may be used to filter cerebrospinal fluid (CSF) from a human or animal subject, heat CSF to a target temperature, cool CSF to a target temperature, apply light treatment to CSF, separate cells via their dielectric properties, apply spiral and/or centrifugal separation, introduce additives to target particles, and/or apply combinations thereof. The method may include the steps of withdrawing fluid comprising CSF, treating the fluid, and returning a portion of the treated fluid to the subject. During operation of the system, various parameters may be modified, such as flow rate.
US10532194B2 Inline storage pouches for use with body fluids
Inline storage pouches and systems for receiving and retaining body fluids from an animal are presented. The inline storage pouch include a flexible pouch body has an interior portion with a fluid storage material disposed within the interior portion. In addition to receiving body fluids, the inline storage pouch may fluidly couple a pressure sensing conduit between a first port and a second port using a first bypass conduit. The first port may be a patient-port interface. The second port may be a device-port interface. Multiple sensors and bypass conduits may be included and associated with a microprocessor that is configured to locate blockages or determine when the inline storage pouch is full. Another inline storage pouch has two chambers and receives and discharges fluids from a pouch connector. Other pouches, systems, and methods are presented herein.
US10532192B2 Regional anesthesia catheter with anchor
Embodiments of the invention provide a system and method for accessing an internal body region using a catheter. The catheter includes a catheter body and a medication lumen positioned within the catheter body for delivering medication to the internal body region. An inflation lumen is positioned within the catheter body. A balloon is in fluid communication with the inflation lumen, and the balloon is configured to move between a collapsed position and an expanded position as fluid enters the balloon through the inflation lumen. An anchor covers at least a portion of the balloon on an outer surface of the catheter body and includes a movable section with a first retracted position and a second deployed position. Upon inflation of the balloon, the movable section of the anchor moves radially outward from the first contracted position to the second deployed position to secure the catheter in the internal body region.
US10532191B2 Catheter
A catheter includes a balloon that has an inner layer and an outer layer having elastic stretching properties, having tubular shapes, and being able to be inflated and deflated in response to a change of internal pressure; and a tubular net-shaped reinforcement member that is disposed between the inner layer and the outer layer such that at least a part thereof is movable with respect to the balloon. The reinforcement member has a first sleeve, and second sleeves which respectively surround both end portions of the first sleeve in an axial direction. A maximally inflated diameter of the second sleeve is set so as to be smaller than a maximally inflated diameter of the first sleeve.
US10532188B2 Anchoring an intravenous cannula
Some embodiments of a medical system include a subcutaneous anchor device that extends outwardly from side wall of an intravenous cannula so as to secure the intravenous cannula in a position relative to a skin penetration point.
US10532181B2 Wearable apparatus
A wearable apparatus capable of altering a physiological parameter such as the heart rate of a user to provide a relaxing or stimulating effect on the user is provided. The apparatus comprises a device capable of engaging the patient's skin to provide a rhythmic tactile stimulus to the user that can alter the user's heart rate and an arrangement for securing the device to the user such that the device can apply the stimulus to the user. The apparatus may be part of a system enabling the device to be controlled remotely. The apparatus may also be configured to provide additional tactile stimuli.
US10532178B2 Water out alarm
The present invention provides for an improved method of determining a water out condition in a humidified gases supply apparatus. The method includes a two step process including a primary determination of a water out condition and a secondary determination of a water out condition. This primary determination is made during observation of the normal operation of the apparatus. During the secondary determination the method takes temporary control over the humidifying part of the apparatus. The secondary determination confirms or contradicts the primary determination.
US10532177B2 Components for medical circuits
Breathable medical circuit components and materials and methods for forming these components incorporate breathable foamed materials that are permeable to water vapor and substantially impermeable to liquid water and the bulk flow of gases. The materials and methods can be incorporated into a variety of components, including tubes, Y-connectors, catheter mounts, and patient interfaces and are suitable for use in a variety of medical circuits, including insufflation, anesthesia, and breathing circuits.
US10532171B2 Tracheostomy or endotracheal tube adapter for speech
A speaking valve adapter is disclosed for assisting with speech or language expression during the respiratory recovery of a human. The speaking valve adapter including a speaking valve port, the port being orthogonal to a first interface port, the first interface port adapted to support tracheostomy or endotracheal tubing, a second interface port adapted to support at least one of a suction tubing and a bronchoscopy tubing, and a third interface port adapted to support a connection to a ventilator. The speaking valve adapter may be used by the patient for introduction of at least one of sounds and words while connected to the ventilator. A corresponding respiratory management system which implements the speaking valve adapter and configurable ventilator settings adapted for assisting with more effective speech or language expression during patient recovery or use is also disclosed.
US10532169B2 Small, low-noise side channel compressor, in particular for devices in ventilation therapy
The invention relates to a small, low-noise side channel compressor for producing a defined volumetric flow, such as is needed in particular for devices for ventilation therapy. This is achieved by means of a new type of shape of the blade chambers (24) in the impeller (12) and the blade chamber walls (29), which separate the blade chambers and become thicker toward the circumference of the impeller, supported by a high-speed drive and a large number of blade chambers (24) at a small impeller diameter.
US10532164B2 Retractable needle assemblies
A retractable needle assembly (1) is disclosed comprising a body portion (10); a needle (50) having a forward end (52) and being movable between an operable orientation in which the forward end projects forwardly from the body portion, and a safe orientation in which said forward end (52) is retracted into the body portion (50). The needle assembly further comprises a deflector (70) mounted in the body portion (50), which is moveable between a first position and a second position, wherein the movement of the deflector (70) between its first and second position urges the needle into its safe orientation, the deflector being biased towards the second position; a latching mechanism which holds the deflector in the first position; and an actuator (90), operable to release the latching mechanism.
US10532160B2 Pen-type drug injection device and optical dose value decoding system with additional sensor to distinguish between dose dialling and dose delivery mode
An optical decoding system comprising: a first optical sensor configured to be directed at a first rotatable component of a drug delivery device; a second optical sensor configured to be directed at a second rotatable component of a drug delivery device; and a processor configured to: receive signals from the first optical sensor, wherein the signals from the first optical sensor represent encoded dosage values present on the first rotatable component; receive signals from the second optical sensor, wherein the signals from the second optical sensor represent whether the second rotatable component is rotating or not; and to determine from the received signals whether the drug delivery device is in a drug dose dialling mode or a drug dose delivery mode.
US10532157B2 Ampule autoinjector systems and methods
An autoinjector is described that includes an outer body, a first trigger, an output needle, and a first compartment. The first compartment is positioned within the outer body and includes (i) a main body, (ii) a first biasing member coupled to the first trigger, and (iii) a protrusion positioned at a distal end of the main body. The autoinjector further includes a second compartment positioned in the outer body and in fluid communication with the first compartment and the output needle. The autoinjector also includes a second biasing member coupled to a second trigger. The first biasing member is configured to, upon application of force to the first trigger, automatically move an ampule in a distal direction relative to the main body to force the ampule against the protrusion, so as to break the ampule and allow a medicament to flow from the ampule to the second compartment.
US10532151B2 Medication infusion device
A wearable infusion device for delivering medication into body of a user, the infusion device comprising a medication container containing a volume of medication to be dispensed; an infusion needle that is fully enclosed in a sterile environment until the infusion needle is inserted into underlying tissue; an infusion needle insertion mechanism associated with the infusion needle, powered by one or more mechanical springs, that when activated, inserts the infusion needle through the skin into underlying tissue; means for delivering medication out of the medication container and into underlying tissue via the infusion needle; and a housing associated with the medication container, the infusion needle, the infusion needle insertion mechanism and the means for delivering medication.
US10532147B2 Method of flushing an extracorporeal blood circuit
The invention relates to a method of flushing an extracorporeal blood circuit, preferably an extracorporeal blood circuit of a dialysis machine, with a flushing liquid, wherein the flushing liquid contains an anticoagulant agent, preferably heparin. The invention further relates to an extracorporeal blood treatment unit, preferably to a dialysis machine, having an extracorporeal blood circuit and a control unit, wherein the control unit is configured to carry out a flushing method in accordance with one of the preceding claims before the start of the treatment and/or intermittently during the treatment.
US10532144B2 Method for removing fluid from a blood filter after completing a blood treatment session by means of flow increase and treatment device for carrying out said method
The present invention relates to a method for removing fluid from a blood filter (19) for the blood treatment of a patient and/or for removing blood from the flood filter (19) after completing the blood treatment session. It further relates to a control and/or regulating device (29), a medical treatment apparatus having a control and/or regulating device (29) with which the method according to the present invention is executable, a digital storage medium, a computer program product as well as a computer program.
US10532143B2 Installation member and peristaltic pump
An installation member and a peristaltic pump are provided that allow work of attachment and work of detachment of a flexible tube to be peristaltic to and from a stator to be performed more easily and smoothly. An installation member that is to be detachably attached to a peristaltic pump including: a stator including an attachment recessed portion, in which a flexible tube to be peristaltic, is attached; a rotor that is rotatably driven in the attachment recessed portion; and a roller that causes the fluid to flow by imparting peristaltic motion to the flexible tube to be peristaltic attached to the attachment recessed portion in a longitudinal direction in association with rotation of the rotor while compressing the flexible tube to be peristaltic in a radial direction. The installation member including: a main body that is attachable to a predetermined portion of the stator, and that is formed integrally with a downstream-side fixing portion of the flexible tube to be peristaltic; and a notch portion that allows an upstream-side fixing portion of the flexible tube to be peristaltic to be positioned.
US10532142B2 Sorbent cartridge to measure solute concentrations
A sorbent based monitoring system for measuring the solute concentration of at least one component of a fluid. The system has a sorbent regeneration system for regeneration of the fluid and has a sorbent cartridge that has at least one material layer. The fluid is conveyed through the sorbent cartridge and contacts at least one sensor after having contacted at least one material layer.
US10532136B2 Noise-suppressing, suction probe apparatus and method
A suction tool having a hollow handle and a probe extending from the handle near one end of the handle to define a lumen in fluid communication with the hollow handle and a fitting, formed to extend near the other end of the handle and shaped to receive a vacuum source drawing fluids through the probe, handle, and fitting. The handle also includes an aperture extending at an acute angle with respect to the axis of the handle.
US10532135B2 Drainage system with O-ring
A drainage system according to certain aspects of the present disclosure may include a container having an interior and a mouth, where the mouth has an outer surface and an opening. The drainage system may further include a frangible seal covering the opening and a cap, where the cap is secured to the mouth and is in fluid communication with a drainage line, and where the cap has an inner surface configured to engage with the outer surface of the mouth. An O-ring may be located at least partially between the outer surface of the mouth and the inner surface of the cap to form a fluid seal between a space defined by the cap and the space located externally of the drainage system.
US10532133B2 Hydrophilic coating for intravascular devices
The present disclosure relates to a coating for medical devices. The lubricious coating includes a primer layer and a top coating layer as well as methods of making and using the same. The primer layer includes a reaction cured product of a multifunctional acrylate and an acid functionalized monoacrylate. The top coating layer includes a reaction cured product of a mixture that includes a hydrophilic polymer comprising polyvinylpyrrolidone, an acid functionalized monoacrylate, and a hydrophilic monomer. The lubricious coating may be coated onto medical devices to form a sensing guide wire, an ultrasound imaging device, and an intravascular imaging device. Associated devices and methods are also provided.
US10532130B2 Soft tissue mimetics and thermoplastic elastomer hydrogels
Provided herein is a soft tissue mimetic formed from a block copolymer hydrogel and methods of making such. The hydrogel comprises a glass formed from a dry blend of polystyrene-poly(ethylene oxide) diblock copolymer (SO) and polystyrene-poly(ethylene oxide)-polystyrene triblock copolymer (SOS) in a molar ratio from between 95:5 and 1:99 SO/SOS and a liquid medium at a concentration between about 32:1 and about 2:1 liquid medium/SO-SOS by weight. The soft tissue mimetic has a fatigue resistance to at least 500,000 compression cycles.
US10532127B2 Methods to produce perforated collagen coated surgical meshes
Methods to produce perforated collagen coated meshes for use as implants have been developed. The method involves positioning needles through the pores of the mesh, coating the mesh with a collagen solution, freezing the coated mesh, removing the needles from the frozen coated mesh, drying the collagen coated mesh, and optionally cross-linking the coated mesh. The method allows perforated collagen coated meshes to be prepared with variable thickness, and without damage to the surface of the mesh. The perforations of the collagen coated meshes may be designed to prevent the formation of fluid pockets when the coated meshes are implanted, and to permit rapid incorporation into host tissue. The perforated collagen coated meshes may be used for soft tissue repair, regeneration or remodeling including, for example, hernia repair, mastopexy, treatment of urinary incontinence, pelvic floor reconstruction, and ligament and tendon repair.
US10532120B2 Scent dispenser with illuminating arrangement
A scent dispenser includes a main body, a liquid tank unit, a diffusing member for diffusing the liquid from the main body, a control module supported in the main body, an audio speaker unit provided in the main body and electrically connected to the control module, and an illuminating arrangement. The illuminating arrangement includes a supporting frame supported by the main body, and a plurality of illuminating units embedded in the supporting frame and electrically connected to the control module, the illuminating units and the audio speaker unit being driven by the control module to deliver an optimal mix of lighting and sound effect respectively while the liquid is diffused and dispensed from the main body.
US10532111B2 Recombinant adeno-associated virus capsids resistant to pre-existing human neutralizing antibodies
The present invention relates to variant AAV capsid polypeptides, wherein the variant capsid polypeptides exhibit an enhanced neutralization profile, increased transduction and/or tropism in human liver tissue or hepatocyte cells (i.e., human hepatocyte cells), or both, as compared non-variant parent capsid polypeptides.
US10532110B2 AAV vectors targeted to the central nervous system
The invention relates to chimeric AAV capsids targeted to the central nervous system, virus vectors comprising the same, and methods of using the vectors to target the central nervous system. The invention further relates to chimeric AAV capsids targeted to oligodendrocytes, virus vectors comprising the same, and methods of using the vectors to target oligodendrocytes.
US10532102B2 Pharmaceutical composition and methods of uses
The present invention provides compositions or formulations comprising the combination of a compound of 5-[3-(4-benzyloxyphenylthio)-fur-2-yl]-imidazolidin-2,4-dione or a salt thereof or hydrate of the foregoing, and a cyclodextrin; or in further combination with an excipient comprising L-Arginine or other additives, wherein the compositions or formulations increases water solubility and oral bioavailability of 5-[3-(4-benzyloxyphenylthio)-fur-2-yl]-imidazolidin-2,4-dione and its related compounds. The method of making or using the compositions or formulations is also disclosed. Such compositions or formulations may be used in treatment of certain diseases including asthma through inhibition of matrix metalloproteinase-12.
US10532095B2 Viral vectors and their use in therapeutic methods
The invention provides viral vectors (e.g., herpes viral vectors) and methods of using these vectors to treat disease.
US10532093B2 Thermostable freeze dried rotavirus vaccine formulation and process to prepare thereof
The present invention relates to a thermostable freeze dried rotavirus vaccine formulation and the process of preparing the same. More specifically the present invention discloses multivalent thermostable liquid, powder or cake based rotavirus vaccine formulation prepared using the freeze drying process, such that the said vaccine formulation possess improved heat-stability, easy to use and transport and highly affordable thereby meeting the requirements of developing and low income country's vaccination program. The said freeze dried rotavirus vaccine formulation along with reconstitution buffer is so engineered to be suitable for filling in appropriate packaging containers/ closures so designed such that they reduce the logistics requirement for storage.
US10532089B2 Iterative discovery of neoepitopes and adaptive immunotherapy and methods therefor
Contemplated cancer treatments comprise recursive analysis of patient-, cancer-, and location-specific neoepitopes from various biopsy sites of a patient after treatment or between successive rounds of immunotherapy and/or chemotherapy to inform further immunotherapy. Recursive analysis preferably includes various neoepitope attributes to so identify treatment relevant neoepitopes.
US10532088B2 Adoptive cellular therapy using an agonist of retinoic acid receptor-related orphan receptor gamma and related therapeutic methods
The invention relates to medical therapy using an agonist of the retinoic acid receptor-related orphan receptor gamma (RORγ) and provides adoptive cellular therapies using an agonist of RORγ, populations of lymphocyte cells that have been exposed to an agonist of RORγ, populations of dendritic cells that have been exposed to an agonist of RORγ, pharmaceutical compositions, and methods for enhancing therapeutic effects of lymphocyte cells and/or dendritic cells in a patient by administering an agonist of RORγ to a patient.
US10532081B2 Method of ameliorating or preventing the worsening or the progression of symptoms of BPH
The embodiments include methods of ameliorating or preventing the worsening or progression and/or ameliorating or preventing the worsening or lack of improvement of symptoms of BPH in mammals, using compositions containing compounds based on small peptides and a pharmaceutically acceptable carrier. The method includes, but is not limited to, administering the compounds intramuscularly, orally, intravenously, intraprostatically, intrathecally, intratumorally, intranasally, topically, transdermally, etc., either alone or conjugated to a carrier to a mammal in need thereof.
US10532070B2 Antiviral composition and applications of iron-doped apatite nanoparticles
Iron-doped apatite nanoparticles (IDANPs) are useful for the prevention, treatment, or alleviation of signs or symptoms associated with viral activation or infection. IDANPs have demonstrated a significant influence over herpes simplex virus 1 (HSV-1) infection of two mammalian cell lines. Specifically, IDANPs decreased HSV-1 infection of African Green Monkey kidney epithelial (Vero) cells by 84% and HSV-1 infection of human lung bronchus (BEAS-2B) cells by 71%. IDANPs consist of hydroxyapatite (HA) doped with iron. HA is a mineral known to be biocompatible and analogous to the inorganic constituent of mammalian bone and teeth and has been approved by the Food and Drug Administration (FDA) for many applications in medicine and dentistry. Lactate Dehydrogenase (LDH) and XTT (2,3-Bis 2-methoxy-4-nitro-5-sulfophenyl-2H-tetrazolium-5-carboxanilide inner salt) cytotoxicity assays revealed that IDANPs are largely non-toxic to Vero, BEAS-2B, and human cervical cancer (HeLa) cells lines. HSV-1 afflicted individuals in the United States have been estimated as high as ⅔ the population. Because IDANPs dramatically decrease HSV-1 infection and are largely non-toxic, their application as an antiviral agent is evident. Further, although iron(III) alone has been shown to diminish replication of deoxyribonucleic acid (DNA)- and ribonucleic acid (RNA)-containing viruses, IDANP cytotoxicity studies indicate that encasement and delivery of iron within an apatite unit cell structure diminishes significantly, and in some cases eliminates, cytotoxicity posed by the introduction of iron(III) alone.
US10532069B2 Compositions and methods for treating joints
Compositions and methods are disclosed for the treatment of osteoarthritis. The compositions comprising combinations of hyaluronic acid, glucosamine, and chondroitin sulfate, can be useful for any synovial joint, including the knee, shoulder, hip, ankle, hands, spinal facet, or temporomandibular joint, both for the relief of pain and for slowing disease progression.
US10532068B2 Dual molecular delivery of oligonucleotides and peptide containing conjugates
Disclosed herein is a method for inhibiting expression of a gene of a subject comprising administering (1) a composition comprising R-(L)a-(G)b; wherein R is an oligonucleotide selected from the group consisting of DNA, RNA, siRNA, and microRNA; L is a linker and each occurrence of L is independently selected from Table 3; G is a targeting ligand and each occurrence of G is independently selected from Table 4; each of a and b is independently 0, 1, 2, 3 or 4; and (2) a composition comprising (P)c-(L)d-(G)e; wherein P is a peptide and each occurrence of P is independently selected from Table 2; L is a linker and each occurrence of L is independently selected from Table 3; G is a targeting ligand and each occurrence of G is independently selected from Table 4; d is 0, 1, 2, 3, 4, 5 or 6; and each of c and e is independently 1, 2, 3, 4, 5 or 6. Compositions in (1) and (2) can be co-administered or sequentially administered.
US10532064B2 Biophosphonate compounds and gamma delta T cell-mediated therapy for treating epstein-barr virus-associated disorders
Aminobisphosphonate pamidronate (PAM) can control Epstein-Barr virus (EBV) associated disorders in humanized mice through a Vγ9Vδ2-T-cell dependent mechanism. This suggests a strong potential for a therapeutic approach using PAM to boost human Vγ9Vδ2-T-cell immunity against EBV associated disorders, such as the lymphoproliferative disease (LPD), posttransplant lymphoproliferative disorder (PLPD), Hodgkin's disease, Burkitt's lymphoma, and nasopharyngeal carcinoma (NPC).
US10532063B2 Method for making bismuth containing liquid pharmaceutical suspensions
A method of producing a liquid pharmaceutical suspension by mixing magnesium aluminum silicate, gellan gum, bismuth subsalicylate, and methyl cellulose.
US10532061B2 Farnesoid X receptor modulators
The present invention provides a compound of formula (I): or a pharmaceutically acceptable salt, solvate, or amino acid conjugate thereof, wherein R1, R2, R3, R4, R5, and R6 are as described herein. The present invention relates generally to selective FXR agonists and to methods of making and using them.
US10532056B2 Therapeutic compositions, combinations, and methods of use
This invention relates to methods comprising administering a FAK inhibitor and an immunotherapeutic agent such as anti-PD-1 or anti-PD-L1; that are useful in the treatment of abnormal cell growth, such as cancer, in mammals, especially humans.
US10532050B2 Formulations of oxabicycloheptanes and oxabicycloheptenes
The invention relates to a pharmaceutical composition comprising a protein phosphatase 2A (PP2A) inhibitor and monosodium glutamate.
US10532048B2 Tetrahydroisoquinolin-1-one derivative or salt thereof
To provide a pharmaceutical, in particular a compound which can be used as a therapeutic agent for irritable bowel syndrome (IBS). It was found that a tetrahydroisoquinolin-1-one derivative having an amide group at the 4-position or a pharmaceutically acceptable salt thereof has an excellent bombesin 2 (BB2) receptor antagonistic action. It is also found that the tetrahydroisoquinolin-1-one derivative is highly effective on bowel movement disorders. From the above, the tetrahydroisoquinolin-1-one derivative of the present invention is useful as a therapeutic agent for diseases associated with a BB2 receptor, in particular IBS.
US10532047B2 Solid forms of ((S)-5-((1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6-oxo-1,6-dihydropyridine-2-carbonitrile
The present disclosure reports solid forms of ((S)-5-((1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl)amino)-1-methyl-6-oxo-1,6-dihydropyridine-2-carbonitrile.
US10532041B2 Formulation comprising glycopyrrolate, method and apparatus
A method is disclosed for making a pharmaceutical composition for pulmonary administration comprising co-jet milling glycopyrrolate and magnesium stearate, wherein the co-jet milled glycopyrrolate and magnesium stearate is then subjected to a conditioning step which includes exposure of the co-jet milled glycopyrrolate and magnesium stearate to humidity. A composition made by this method is also disclosed.
US10532040B2 Methods of treating cancer with herbacetin
The invention provides methods, uses and compounds for treating cancers. For example, certain embodiments provide a method for treating cancer in a mammal comprising administering to the mammal an effective amount of 3,5,7,8,4′-Pentahydroxyflavone, or a pharmaceutically acceptable salt thereof. Certain other embodiments of the invention provide methods for inactivating ornithine decarboxylase (ODC) in a cell comprising contacting the cell in vitro or in vivo with an effective amount of 3,5,7,8,4′-Pentahydroxyflavone, or a pharmaceutically acceptable salt thereof. The invention also provides a dermal product comprising 3,5,7,8,4′-Pentahydroxyflavone, or a pharmaceutically acceptable salt thereof, wherein the product prophylactically or therapeutically treats sunburn or other sun exposure and/or skin cancer in a mammal.
US10532038B2 Beta-3 adrenoceptor agonists for the treatment of pulmonary hypertension
The invention relates to the use of selective agonists of beta-3 adrenergic receptors for the treatment and/or prevention of pulmonary hypertension.
US10532037B2 Oral combination drug formulation comprising a non-steroidal anti-inflammatory drug and a complementary low dose of tranexamic acid for the treatment of menstrual pain accompanied with excessive menstrual blood loss
A method for relieving menstrual pain and reducing menstrual blood loss in a female is provided. The method comprises administering to the female an oral combination drug formulation comprising a first therapeutically effective dose of a non-steroidal anti-inflammatory drug (NSAID) and a second complementary low dose of tranexamic acid, wherein the NSAID is formulated to relieve the menstrual pain and to reduce a volume of menstrual blood loss of the female, wherein the dose of tranexamic acid ranges from 50 mg to 425 mg per oral combination drug formulation.
US10532036B2 Combination composition
A combination pharmaceutical composition for the treatment of pain including about 125 mg to about 150 mg ibuprofen and about 475 mg to about 500 mg paracetamol.
US10532035B2 Methods for improvement of visual function and compositions used therein
Methods herein are described for improvement in visual function by administering macular carotenoid compositions containing an effective daily dose, to a subject in need thereof. More particularly, methods herein are described and include use of the compositions herein by identifying a subject in need thereof, administering a daily dose of lutein and/or zeaxanthin isomers, comprised of meso-zeaxanthin and R,R zeaxanthin, alone or in combination thereof, the composition also including at least one food grade excipient, and evaluating visual performance. The subject is exposed to light of variable wavelengths and intensity and is suffering from visual fatigue. The composition improves contrast sensitivity, glare performance, photo stress recovery, and/or macular pigment optical density, and thus alleviates visual fatigue. The composition is safe for human and other animals for consumption and can be used for improvement in visual health in the subject, when administered in an effective amount.
US10532034B2 Inhibition of glutaminase C
The present invention relates to a method of reducing the production of glutamate from glutamine by glutaminase C in a cell or tissue. The method involves inhibiting glutaminase C activity in the cell or tissue under conditions effective to reduce production of glutamate from glutamine. Compounds for carrying out this method are also disclosed and include those of formula (III): wherein B, R1c, R2c, m, and n are defined herein.
US10532033B2 Microreservoir system based on polysiloxanes and ambiphilic solvents
The invention relates to a transdermal therapeutic system on the basis of polysiloxane which contains microreservoirs filled with an active substance and one ambiphilic solvent.
US10532032B2 Rolled collagen carrier
The invention relates to a process for the preparation of a rolled compressed collagen carrier and a process for un-rolling said rolled compressed collagen carrier. Said rolled compressed collagen carrier is ready for use in minimally invasive surgery. The invention also relates to a rolled compressed collagen carrier for use in the prevention or treatment of injury associated with performing minimally invasive surgery.
US10532031B2 Controlled release dosage form with enhanced pharmacokinetics
The present invention provides a simple and improved dosage form that is capable of providing a controlled release of GABAB receptor agonist contained in the core thereof. The invention also provides methods of administering the dosage form and of treating conditions that are therapeutically responsive to GABAB receptor agonist.
US10532023B2 Camellia japonica extract and cosmetic compositions containing same
Disclosed is a Japanese camellia extract, obtained by extracting Camellia japonica flowers by way of a fatty substance or fatty substance mixture, and to a cosmetic composition including one such extract that has, in particular, a skin-moisturizing effect.
US10532015B2 Oral care compositions
An oral care composition comprising zinc phosphate, stannous fluoride, arginine or lysine and an organic acid buffer system, as well as methods of using the same.
US10532012B2 Core shell silica and methods for the same
Methods for preparing high loading core shell silica (CSS) particles, or CSS particles having a relatively greater amount of surface active silicate groups than CSS particles prepared according to conventional methods is provided. The method may include contacting silica particles with a base having a first metal ion to produce core shell silica particles. Each of the core shell silica particles may include a silica core and a silicate of the first metal ion etched on a surface of the silica core. The method may also include contacting each of the core shell silica particles having the silicate of the first metal ion with an acidic aqueous solution including a metal salt having a second metal ion to produce core shell silica particles including the silica core and a silicate of the second metal ion on the surface of the silica core.
US10532004B2 Synchronization of repetitive therapeutic interventions
A medical device of the type used for assisting a user in manually delivering repetitive therapy to a patient (e.g., chest compressions or ventilations in cardiac resuscitation), the device comprising a feedback device configured to generate feedback cues to assist the user in timing the delivery of the repetitive therapy, at least one sensor or circuit element configured to detect actual delivery times, at which the user actually delivers the repetitive therapy, and a processor, memory, and associated circuitry configured to compare the actual delivery times to information representative of desired delivery times to determine cue times at which the feedback cues are generated by the feedback device.
US10531999B2 Device for massaging a user
A device for massaging a user having an elongate body and one or more ribs extending therefrom, the one or more ribs forming an undulation, whereby urging the one or more ribs against a body of the user and rolling the elongate body there along massages the user.
US10531998B2 Patient positioning support structure with trunk translator
A patient support structure includes a pair of independently height-adjustable supports, each connected to a patient support. The supports may be independently raised, lowered, rolled or tilted about a longitudinal axis, laterally shifted and angled upwardly or downwardly. Position sensors are provided to sense all of the foregoing movements. The sensors communicate data to a computer for coordinated adjustment and maintenance of the inboard ends of the patient supports in an approximated position during such movements. A longitudinal translator provides for compensation in the length of the structure when the supports are angled upwardly or downwardly. A patient trunk translator provides coordinated translational movement of the patient's upper body along the respective patient support in a caudad or cephalad direction as the patient supports are angled upwardly or downwardly for maintaining proper spinal biomechanics and avoiding undue spinal traction or compression.
US10531996B2 Supporting surface with programmable supports and method to reduce pressure on selected areas of a body
A system and method to reduce pressure on selected areas on a body include an array of programmable supports and at least one sensor to detect a physical property of the body. Each programmable support of the array of programmable supports includes an adjustable member and a mechanism to adjust the length of the adjustable member based on the detected physical property of the body.
US10531995B2 Patient support plate including accessory part
The invention provides a patient supporting plate (2) consisting of at least one first and one second patient supporting components (3, 4) and an accessory part (7). The first or the second patient supporting component (3, 4) is provided with a hinge (5) having a swivel axis (6). The hinge (5) has a drive element (11) for swiveling the patient supporting components (3, 4), as well as at least one coupling element (8) for coupling the first patient supporting component to the second patient supporting component (3, 4). The drive element (11) and the coupling element (8) are arranged juxtaposed in the direction of the swivel axis (6) and can be fastened to one another by means of at least one first detachable fastening element (17). The accessory part (7) can be fastened to the coupling element (8) by means of the first detachable fastening element (17) or a second detachable fastening element (24), by providing a first through opening (14) running in the direction of the swivel axis (6) in the drive element (11) and a second through opening (15) in the coupling element (8) for the first or second fastening element (17, 24) and also an aligned receptacle (16) in the accessory part (7), so that the fastening element (17, 24) can be inserted into the first opening (14) from the drive element (11) side located opposite the coupling element (8) and connected to the accessory part (7).
US10531992B2 Absorbent article having a one-piece chassis and integral side portions
An absorbent article which has a one-piece chassis and integral side portions. The one-piece chassis can be a bi-laminate material and can have a liquid permeable layer and a liquid impermeable layer bonded together. The side portions can be integrally formed from the one-piece chassis.
US10531990B2 Absorbent article with leg cuffs
A disposable absorbent article may include a chassis that includes a topsheet, a backsheet, and an absorbent core disposed between the topsheet and the backsheet; and a leg gasketing system. The leg gasketing system may include an inner cuff and an outer cuff; the inner cuff may include an inner cuff folded edge and an inner cuff material edge and the outer cuff may include an outer cuff folded edge and an outer cuff material edge such that the web of material is folded laterally inward to form the outer cuff folded edge and folded laterally outward to form the inner cuff folded edge, and the leg gasketing system further including a leg gasketing system pocket with an opening on an inboard longitudinal edge of the leg gasketing system pocket. The disposable absorbent article also includes at least one channel in the absorbent core.
US10531989B2 Method for fabricating absorbent articles
The present invention relates to a method for fabricating absorbent article having multiple layers, and deformed zones of targeted performance, and colored regions, the method comprising the steps of forming discrete features on at least one layer, printing colored regions on at least one layer, integrating multiple layers to form an absorbent assembly, and cutting the absorbent assembly into individual absorbent articles, wherein the steps are carried out continuously.
US10531981B2 Device for non-surgical cold treatment of disorders
A device for non-surgical cold treatment of disorders, like warts includes a container containing a refrigerant having an outlet and a valve communicating with the outlet. An applicator is mounted to the container, said applicator having an outer wall and forming a chamber at least when connected to the container, a heat exchanger within the chamber in fluid communication with the outlet of the container and receiving refrigerant when the valve of the container is opened. A closed contact member is in heat exchange contact with the heat exchanger and is exposed to an outer side of the applicator. The heat exchanger includes a porous member made of a material having a high thermal conductivity and adapted to conduct fluid refrigerant from the outlet of the container to the chamber while the refrigerant extracts heat from the heat exchanger and the contact member.
US10531980B2 Portable electronic moxibustion therapy device
Disclosed is a portable electronic moxibustion therapy device which can be conveniently carried after being charged by a user to provide the effects of conventional moxibustion treatment anywhere and anytime, and which can maximize the effects of moxibustion treatment by directly applying heat stimulation while being near but not in direct contact with an acupuncture point to be treated and simultaneously providing an indirect thermal effect continuously to the surrounding area and the area around the acupuncture point to be treated. The portable electronic moxibustion therapy device according to the present invention comprises: an upper main body including a battery and a control circuit unit provided therein, and separate the skin from the bottom end of the funnel portion.
US10531978B2 System for the production of a medical product, as well as method for operation of such a system
A system for the production of a medical product, above all in the form of an ostomy bag, as well as a method for operation of such a system, uses a highly flexible modular system concept, in which individual feed lines for semi-finished products are provided. The feed lines can transfer semi-finished products to a main line in pre-assembled manner. In the main line, ultimate processing of the semi-finished products to produce the finished product or a further semi-finished product takes place, with the greatest possible work precision, in contrast to conventional systems that guide different film systems in different planes at a distance from one another, to allow pre-processing steps, before bringing the films together in one plane and welded to one another.
US10531973B2 Apparatus for treating and supporting extremities or a portion of a body
A support device comprising at least one skeleton structure and at least two coupling articles, wherein each of the two coupling articles are connected to an end section of the skeleton structure, such that the support device includes at least four degrees of freedom.
US10531967B2 Walking assistance apparatus and operation method of the same
A walking assistance apparatus may include a driver configured to assist movements of a first joint related to a right leg of a user and a second joint related to a left leg of the user, a sensor configured to measure a first joint angle corresponding to the first joint and a second joint angle corresponding to the second joint, and a controller configured to generate a walking assist profile based on a previous step of the user, modify the walking assist profile based on the first joint angle and the second joint angle, and control the driver based on the modified walking assist profile.
US10531961B2 Anchoring device and system for an intervertebral implant, intervertebral implant and implantation instrument
Anchoring devices, anchoring systems for intervertebral implants, intervertebral implants, and instruments and methods for implanting implants are disclosed. In preferred configurations, these various objects share the feature of comprising or cooperating with an anchoring device having a body comprising at least one curved plate elongated along a longitudinal axis, designed to be inserted through a passage crossing at least a part of implant, in order to penetrate into at least one vertebral endplate and attach implant onto this vertebral endplate by means of at least one stop retaining the implant, characterized in that the body comprises at least one longitudinal rib on at least a part of at least one of its faces, said rib being designed to cooperate with a groove made in passage of implant. In some preferred configurations, anchoring device comprises withdrawal stops or latches, and/or means for withdrawing the anchor from an inserted position.
US10531957B2 Modified demineralized cortical bone fibers
Surgical implants (or grafts) for the repair of bone defects, more particularly, surgical implants that include demineralized bone fibers, are disclosed. The surgical implants have a wettability time of less than 5 minutes and a residual moisture content of less than 6% by weight, and they remain cohesive and retain their shape upon complete rehydration. Methods for making such implants and for increasing their wettability and ensuring uniform density are also disclosed.
US10531953B2 Stent-valve, delivery apparatus and method of use
A delivery apparatus for delivering a stent-valve for implantation within the body, the delivery apparatus configured for introduction into the body through an arterial introducer of a type having a stem insertable into the body and a mouth section that remains outside the body, the mouth section including a haemostasis valve, and wherein the delivery apparatus comprises: a first constraining sheath at a stent-valve accommodation region of the apparatus at a distal end of the apparatus, and configured for constraining at least a portion of a stent-valve at the accommodation region in a radially collapsed configuration; a delivery introducer captive on the delivery apparatus, and slidable between a first position surrounding at least a portion of the stent-valve accommodation region, and a second position in which the delivery introducer slides proximally of the stent-valve accommodation region; wherein the delivery introducer is insertable at least partly into the mouth of a said arterial introducer, the delivery introducer configured for introducing the stent-accommodation region through the haemostasis valve.
US10531951B2 Transcatheter prosthetic heart valve and delivery system
A prosthetic heart valve for an endoprosthesis used in the treatment of a stenotic heart valve and/or a heart valve insufficiency. The prosthetic heart valve comprises a plurality of leaflets (3,4,5) which are able to switch between their open and close position in response to the blood flow through the heart. The leaflets are attached into a collapsible wire valve frame involving a stent part (1) and a wire mesh part (2) that complement each other in many ways. The prosthetic valve comprises additional elements (6) for its correct positioning and stabilization.
US10531950B2 Intraocular lens having an extended depth of focus
An intraocular lens, comprising an optic having an anterior surface and a posterior surface, providing a refractive base power, at least one of the anterior surface and the posterior surface having disposed thereon a profile comprising steps having heights determined by combining three constituent diffractive profiles. The diffractive profiles correspond to powers p1, p2 and p3, the powers being different than one another and each power being a positive power less than about 1D or about 1.25D. Each of the diffractive profiles having step heights causing a phase delay, relative to aqueous fluid, of 0.6 to 1.2 times 2π for 546 nm light. The combined profile defined by the function: z=max (diffractive profile (p1), diffractive profile (p2), diffractive profile (p3)), where p3>p2>p1.
US10531946B2 Devices and methods for assisting valve function, replacing venous valves, and predicting valve treatment success
Devices and methods for assisting valve function, replacing venous valves, and predicting valve treatment successes. In an exemplary embodiment of an endograft body configured for expansion within a luminal organ, the endograft body comprises (a) a first portion having a proximal end defining a proximal end aperture and a distal end defining a distal end aperture, the first portion configured to increase a velocity of fluid flowing therethrough, (b) a second portion having a second portion proximal end defining a second portion proximal end aperture and a second portion distal end defining a second portion distal end aperture, wherein the distal end of the first portion is adjacent to the second portion proximal end, and (c) a valve portion positioned at or near the second portion proximal end, the valve portion configured to receive the fluid flowing through the distal end aperture of the first portion.
US10531945B2 Methods and devices for minimally invasive transcatheter coronary artery bypass grafting
Systems and methods for performing transcatheter coronary artery bypass grafting procedures are provided. The methods generally involve passing the graft from the aorta to the coronary artery through the pericardial space. The systems include poke-out wires, a coring device, and devices for forming anastomoses at the proximal and distal ends of a vascular graft.
US10531944B2 System for controlling an implantable device on the basis of commands issued by a user
The invention relates to a system for controlling a device implanted in a human or animal body on the basis of voluntary commands issued by a user without the use of any external peripheral. The user issues a voluntary command to the implanted device by applying a specific and predetermined code, consisting of at least one mechanical action and of at least one additional piece of information. Each mechanical action and each additional piece of information are measured by at least one sensor. The output signal(s) of the sensor(s) are processed and used to validate the predetermined code by means of the identification of at least one mechanical action executed by the user and combined with at least one piece of additional information, and the comparison thereof with a corresponding reference model. The invention further relates to a method for detecting an actuation control of an implantable device.
US10531935B2 Orthodontic archwire
An orthodontic archwire is configured to be inserted into an archwire slot of an orthodontic bracket and is configured to be elastically compressed in a plane that is generally parallel to the plane of the arch form of the archwire. The archwire may include a first exterior surface, a second exterior surface spaced from the first exterior surface, and a resilient element disposed between the first and second exterior surfaces, wherein the resilient element is elastically deformable such that a distance between the first and second exterior surfaces may be decreased upon application of a compressive force on the archwire.
US10531933B2 Illuminated telescoping cannula
An illumination system includes a surgical tool and an attachable cannula comprising a transparent or semi-transparent material capable of carrying light from the proximal end to the distal end of the cannula, thereby illuminating the surgical field through components that do not occupy space that may otherwise be used for optics of the tool. The illumination system further comprises one or more illumination sources disposed at the proximal end. The illumination source may be optically coupled with the cannula at the hub or other appropriate location. The cannula comprises a sterilizable polymer which functions as a waveguide. A waveguide is a material medium that confines and guides light. When in use, the light source connected to the hub provides light which may be guided to the distal end of the cannula or any other suitable location. Thus, the sheath provides structure-guided illumination resulting in the illumination of the surgical site.
US10531930B2 Robotic system
A robot system comprises a base (2), a robot arm (1) connected to the base, a camera (10), at least one objective lens in the camera (10) being movable with the robot arm (1), and a screen (16). A control unit (15) is configured to detect a change in the distance between an object (21) detected by the camera (10) and the objective lens, and to vary the zoom factor of a zoom function of the camera (10) according to the change in distance.
US10531928B2 Drive mechanisms for robot arms
A robot arm comprising a joint mechanism for articulating one limb of the arm relative to another limb of the arm about two non-parallel rotation axes, the mechanism comprising: an intermediate carrier attached to a first one of the limbs by a first revolute joint having a first rotation axis and to a second one of the limbs by a second revolute joint having a second rotation axis; a first drive gear disposed about the first rotation axis, the first drive gear being fast with the carrier; a second drive gear disposed about the second rotation axis, the second drive gear being fast with the second one of the limbs; a first drive shaft for driving the first drive gear to rotate about the first rotation axis, the first drive shaft extending along the first one of the limbs and having a first shaft gear thereon, the first shaft gear being arranged to engage the first drive gear; a second drive shaft for driving the second drive gear to rotate about the second rotation axis, the second drive shaft extending along the first one of the limbs on a first side of a plane containing the second rotation axis and extending through that plane to the second side of that plane; and an intermediate linkage that meshes with the second drive shaft on the second side of the plane and that couples the second shaft gear to the second drive gear.
US10531923B2 Method and system for image processing to determine blood flow
Embodiments include a system for determining cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart, and create a three-dimensional model representing at least a portion of the patient's heart based on the patient-specific data. The at least one computer system may be further configured to create a physics-based model relating to a blood flow characteristic of the patient's heart and determine a fractional flow reserve within the patient's heart based on the three-dimensional model and the physics-based model.
US10531919B2 Device and method for the treatment of the vaginal canal and relevant equipment
A device and method for the treatment of the vaginal canal by a laser beam, includes a vaginal canal wall retractor, associated to a system for directing the laser beam towards a wall of the vaginal canal.
US10531916B2 Microwave-irradiating instrument
Microwave-irradiating surgical instruments for endoscopic forceps or scope-assisted surgery forceps that have long lead wires often generate heat even during microwave transmission and a water supply device for cooling is necessary. Accordingly, conventional surgical instruments that irradiated energy such as microwaves had a separate passage for passing water (a water supply device) inside the forceps or endoscope. Due to the space occupied by said water supply device, the image cable or work hole diameter could not be enlarged. Moreover, the presence of the water supply device made surgery difficult. The present invention was completed by the discovery that a microwave-irradiating instrument wherein the central conductor is hollow and forms a channel and said channel is used as a water supply tube, etc. solves the above problems without affecting microwave irradiation efficiency.
US10531908B2 Method for heat treating biological tissues using pulsed energy sources
A method for heat treating biological tissues includes providing a pulsed energy source having energy parameters selected so as to raise a target temperature to a level to achieve a therapeutic effect, while the average temperature rise of the tissue over a prolonged period of time is maintained at or below a predetermined level so as not to permanently damage the target tissue. Application of the pulsed energy source to the target tissue induces a heat shock response and stimulates heat shock protein activation in the target tissue so as to therapeutically treat the target tissue.
US10531906B2 Medical vapor generator
A medical vapor system and method is provided. The medical vapor system can include a fluid conduit having an inlet, an outlet and a heating section, the inlet being adapted and configured to be connected to a source of liquid water, a resistance heater disposed and configured to generate heat and conduct the heat to the heating section of the fluid conduit to vaporize liquid water flowing through the heating section, a power supply operatively connected to the heater, and a controller adapted to control production of water vapor by the system. Methods of use are also provided.
US10531903B2 Orthopedic break-off screws, tools for inserting such screws, and related systems and methods
A system for inserting an anchor member into bone includes a receiving member and an anchor member receivable within the receiving member. The receiving member is elongate along a longitudinal axis and has a proximal end and a distal end spaced from the proximal end along the longitudinal axis. The receiving member has an internal surface that defines a transmission element. The anchor member includes an engagement element configured to rotatably engage the transmission element such that the transmission element is configured to drive the anchor member in a distal direction relative to the transmission element so as to rotatably decouple the engagement element from the transmission element. The distal direction extends from the proximal end to the distal end of the receiving member and is parallel with the longitudinal axis.
US10531892B2 Surgical needle
The disclosure provides examples of a surgical needle for entering a joint space through tissue, such as the hip joint. The surgical needle includes a stylet movable within a hollow body. The hollow body has at one end, a tip of a bevel for cutting tissue and at another end, a feedback member providing a surgeon with tactile feedback. The stylet has at one end, a resistance reducing member that when positioned a preset distance from the bevel reduces the resistance of the surgical needle through tissue. At the other end of the stylet is a stylet hub. In some examples of the surgical needle, the stylet hub includes a proximal stop, stylet locking member and/or locking member. The surgical needle advantageously provides tactile feedback, reduces resistance, and minimizes or prevents damage to delicate structures.
US10531891B2 Tissue slitting methods and systems
Methods and systems for separating an object, such as a lead, from formed tissue are provided. Specifically, a tissue slitting device is configured to engage patient formed tissue at a slitting engagement point. While the object is subjected to a first traction force, the tissue slitting device is caused to move further into the engaged tissue and slit the tissue past the point of engagement. The slitting device causes the tissue to separate along an axial direction of the length of the formed tissue and releases at least some of the force containing the object. The methods and systems are well suited for use in cardiac pacing or defibrillator lead explant procedures.
US10531889B2 Scissor mounted blood spray shield
A releasably attached surgical scissor spray shield is mounted immediately proximate to the scissor blade. The shield controls the spray at the source thus shielding not only the user, but all personnel in the vicinity when an umbilical cord or the like is cut. The mounting mechanisms for the shield releasably, yet securely attaches the spray shield to the scissors so the shield remains immediately proximate to the scissor blades and umbilical cord yet does not restrict the opening of the scissor shear blades. The shield is mounted in close proximity to the cutting operation of the scissors to thereby deflect blood spray immediately adjacent to the source of the spray. The shield does not restrict the operational movement of the scissor blades and arms during the cutting operation.
US10531888B2 Methods for efficiently reducing the appearance of cellulite
A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece. The device and method cut the fibrous structures under the skin that cause cellulite at an angle substantially parallel to the surface of the skin and replace these structures with a non-cellulite forming structure by deploying a highly fibrous mesh through a single needle hole to create a highly fibrous layer directly or through wound healing processes.
US10531887B2 Powered surgical instrument including speed display
A surgical instrument comprising an end effector configured to grasp tissue. The end effector comprises at least one sensor configured to measure a parameter corresponding to a thickness of the grasped tissue. The surgical instrument further includes a firing member movable during a firing stroke to cause a motion at the end effector and a motor configured to drive the firing member. A feedback indicator or display is configured to display the speed of the firing member according to one of a plurality of zones of speed, such as the relative speed of the firing member.
US10531883B1 Aspiration thrombectomy system and methods for thrombus removal with aspiration catheter
A thrombectomy removal system includes a catheter having a distal end and defining a lumen filled with a liquid column having a proximal portion and a distal portion, a vacuum source, a vent liquid source, and a vacuum and vent control system configured to cyclically connect or disconnect the vacuum source and the vent liquid source to change a level of vacuum at the distal end and substantially prevent forward flow. The vacuum source and the vent source are respectively fluidically connected to the vacuum and vent valves. A manifold connects the proximal portion to the vacuum and vent sources through the valves. Control of the valves prevents forward flow of the distal portion out from the distal end during each cycle. Each cycle can have states including vacuum-only, first double-closed, vent-only, and second double-closed. A time of the double-closed states can be no greater than 30 ms.
US10531881B2 Target apparatus for aligning a surgical drilling instrument
A target apparatus for aligning a surgical drilling instrument that includes a pointer mechanism for arranging at a location on a bone where a drilled hole that is to be formed is intended to emerge, a guide mechanism for guiding the surgical drilling instrument, and an adjustable connection mechanism with a first end, which is connected to the guide mechanism, and a second end, which is connected to the pointer mechanism. The adjustable connection mechanism comprises a first component, a second component and a locking mechanism. The second component is movable relative to the first component along a predetermined path. The first component is elastically deformable by the locking mechanism such that the second component can be locked relative to the first component by clamping.
US10531877B2 Interlocking loop coupling/decoupling system for deploying vascular implant devices
In a system and method for deployment of an implant device, the implant device includes a first loop at its proximal end, and a deployment tool has a second loop attached at its distal end. A release wire slidably disposed within the deployment tool has a distal end extending through the first and second loops to releasably couple the implant device to the deployment tool, and a proximal portion extending from a proximal end of the deployment tool, which is held in a retraction device. The retraction device is operable to hold the proximal end of the deployment tool and to pull the release wire proximally through the deployment tool until the distal end of the release wire is withdrawn from the first and second loops to decouple the implant device from the deployment tool.
US10531876B2 Systems and methods for delivering intravascular implants
Systems and methods are provided for delivering and mechanically detaching embolic coils. The systems disclosed herein comprise a mechanical detachment mechanism to intravascularly release an embolic coil. The methods disclosed herein comprise a various triggering mechanisms to detach embolic coils.
US10531868B2 Apparatus and methods for accessing and closing multiple penetrations on a blood vessel
Multiple vascular wall penetrations are formed and sealed in a single blood vessel, typically a vein, for performing cardiac and other catheter-based procedures. Access sheaths are placed in two or more tissue tracts each having a vascular wall penetration at a distal end and into a lumen of the blood vessel. A catheter is advanced though each of the access sheaths to perform a therapeutic or diagnostic procedure. A vascular closure device is introduced through each access sheath, typically sequentially, and an occlusion element at a distal end of the device is deployed against an inner wall of the blood vessel in a manner so that the adjacent access sheath does not interfere or overlap with the deployed occlusion element. The vascular penetration at the distal end in that tissue tract may then be sealed prior to using another vascular closure device to seal a caudally adjacent vascular wall penetration.
US10531867B2 Sinus venosus atrial septal defect treatment device
The sinus venosus atrial septal defect (“ASD”) treatment device includes has a generally tubular or funnel shaped configuration. A first end of the device can have a diameter that is less than a diameter of a second end of the device. The device can be inserted in the right upper right pulmonary vein PV. The second end of the device is configured to expand in a skirt-like configuration once the device is positioned in the right upper right pulmonary vein PV. In this manner, the device closes the upper sinus venosus hole and diverts anomalous pulmonary venous drainage into the left atrium.
US10531866B2 Techniques for providing a replacement valve and transseptal communication
A method is provided, comprising: (1) making a transapical puncture into a left ventricle of the heart; (2) making a transseptal fenestration in the heart; (3) delivering a prosthetic valve via the transapical puncture and implanting the prosthetic valve at a mitral valve of the heart; and (4) subsequently to delivering the prosthetic valve and making the transseptal fenestration, closing the transapical puncture. Other embodiments are also described.
US10531863B2 Quick disconnect assembly and method of use
A quick disconnect assembly including a tubular housing. The housing includes a cam pin secured to the housing and a nut positioned within the housing cannulation. The nut has a first threaded channel adapted to engage a threaded shaft, a second, non-threaded channel extending at an angle to the first channel, and an arcuate groove formed on an outer surface of the nut. When the cam pin of the housing engages the groove at about a distal end of the nut, the nut is positioned in a loading position where the second channel extends approximately parallel to the longitudinal axis of the housing. When the cam pin engages the groove at about a proximal end of the nut, the nut is positioned in a locking position where the first channel extends approximately parallel to the longitudinal axis of the housing.
US10531858B2 Methods and systems for guiding the acquisition of ultrasound images
A method of presenting a suggested path for an ultrasound probe along a patient's surface includes obtaining a three-dimensional, non-ultrasound image of the patient and an ultrasound image of the patient. A treatment area is defined within the within the three-dimensional, non-ultrasound image, and using the images, defining a scanning site contour of an anatomical structure of interest within the patient and an external contour of the patient's surface. A preferred path of the ultrasound scan is projected onto the external contour such that an operator can reproduce the ultrasound scan without knowledge of the anatomical structure of interest.
US10531853B2 Medical imaging apparatus program installable in medical imaging apparatus and medical imaging method
A medical imaging apparatus includes a cardiac lumen region identifying unit, a myocardium identifying unit, and a generating unit. The cardiac lumen region identifying unit is configured to identify a cardiac lumen region from a medical image including a heart region. The myocardium identifying unit is configured to identify a face of a myocardium region obtained by extending a face of the cardiac lumen region, identified by the cardiac lumen region identifying unit, by a certain distance toward a myocardium side. The generating unit is configured to generate a color-coded image in which the face of the myocardium region, identified by the myocardium identifying unit, is colored in colors according to signal values of the medical image corresponding to positions on the face of the myocardium region.
US10531851B2 Dual energy x-ray coronary calcium grading
Methods and apparatus for grading coronary calcium, including an example apparatus that includes a set of logics and a memory that stores a set of radiographic images. The set of logics includes an image acquisition logic that acquires a set of radiographic images of a region of tissue, the set of radiographic images including a low-energy reference x-ray image and a higher-energy floating x-ray image, a registration logic that produces a set of registered images from a plurality of members of the set of radiographic images, an enhancement logic that produces a set of calcium-enhanced images from the set of registered images, a post-enhancement logic that produces a bone image from the set of calcium-enhanced images, and a grading logic that computes a coronary heart disease prediction score based, at least in part, on the bone image and a set of features extracted from the bone image.
US10531847B2 X-ray detector and X-ray imaging apparatus having the same
Disclosed is an X-ray detector having impact resistance and an X-ray imaging apparatus having the X-ray detector. The X-ray imaging apparatus comprises an X-ray source for generating and irradiating X-rays and an X-ray detector for detecting the X-rays irradiated from the X-ray source. The X-ray detector comprises a main body having a bottom plate including a joining groove, a detector panel arranged inside the main body for converting X-rays irradiated from the X-ray source into electric signals, and a middle block arranged inside the main body to support the detector panel. The middle block has a boss configured to protrude toward the bottom plate of the main body. The boss is inserted into the joining groove. A buffer member is arranged in at least part of the joining groove to prevent the boss from coming into contact with the joining groove.
US10531845B2 Systems and methods for image correction in an X-ray device
A method for image correction in a mobile X-ray device includes obtaining an X-ray image corresponding to a region of interest, where the X-ray image includes a projection of the region of interest by an X-ray beam on a detector plane. The method further includes receiving a tilt parameter corresponding to the detector plane. Moreover, the method includes generating a corrected X-ray image based on the X-ray image and the tilt parameter using a perspective projection technique, where the corrected X-ray image corresponds to a projection of the region of interest on a corrected detector plane.
US10531843B2 Couch device, X-ray CT apparatus, and medical image diagnostic apparatus
A couch device according to an embodiment includes a couchtop, shape control members, and driving circuitry. The couchtop includes a movable base couchtop and a transformable couchtop mounted above the movable base couchtop and capable of bending a part thereof from a flat shape. The shape control members control the shape of the transformable couchtop. The driving circuitry moves the couchtop to an opening of a gantry device that collects data for taking medical images. The transformable couchtop includes divided couchtops, and transformation support members for fixing the transformable couchtop to the movable base couchtop are fitted to divided sections. Each of the shape control members adjusts a position of a specific transformation support member so that an installation location thereof is a fixed point of the movable base couchtop.
US10531839B2 System and method of marking cardiac time intervals from the heart valve signals
A system for marking cardiac time intervals from heart valve signals includes a non-invasive sensor unit for capturing electrical signals and composite vibration objects, a memory containing computer instructions, and one or more processors coupled to the memory. The one or more processors causes the one or more processors to perform operations including separating a plurality of individual heart vibration events into heart valve signals from the composite vibration objects, and marking cardiac time interval from the heart valve signals by detecting individual heartbeats and processing cumulative energy within the individual heartbeat to set a threshold to set a marking point.
US10531832B2 Systems, apparatus, and methods for detection and monitoring of chronic sleep disorders
An apparatus for monitoring a sleep parameter of a user includes an adhesive pad configured to conform to a surface of the user and a flexible element coupled to the adhesive pad. The flexible element includes a conductive fabric, and exhibits a modified electrical property in response to an applied force. The apparatus also includes a power source electrically coupled to the flexible element, and an electrical circuit electrically coupled to the power source and the flexible conductive element. The electrical circuit is configured to detect, during use, a change in an electrical property of the flexible element.
US10531831B2 Non-rigid wearable devices
Systems, devices, and methods are provided for a non-rigid wearable device comprising electrical circuitry and a support structure supporting the electrical circuitry. The support structure having rigid sections that rigidly support components of the electrical circuitry to protect components and/or solder joints from stress due to deflection and having non-rigid or flexible sections where there are no solder connections present on the electrical circuitry and/or where there are interconnecting traces present on the electrical circuitry that can tolerate stress due to deflection.
US10531825B2 Thresholding methods for lesion segmentation in dermoscopy images
Systems and methods facilitate segmenting a dermoscopy image of a lesion to facilitate classification of the lesion. A dermoscopy image is received from an image source; pre-processed; and segmented. Segmenting the pre-processed dermoscopy image includes applying a thresholding algorithm to the dermoscopy image. The thresholding algorithm includes at least one of a Huang auto-thresholding algorithm, a Li auto-thresholding algorithm, a Shanbhag auto-thresholding algorithm, an Otsu auto-thresholding algorithm, or an Isodata thresholding algorithm. A weighted border error metric is provided to allow prediction of whether segmentation is likely to avoid excluding portions of the lesion. A test is provided for determination of whether image inversion is needed for the methods to provide optimal borders. An iterative expansion algorithm is provided to for determine whether expansion is needed for the methods to provide optimal borders and to determine the degree of expansion needed for more inclusive segmentation.
US10531815B2 User-steered on-the-fly path planning
A method, system, and program product are provided for user-steered, on-the fly path planning in an image-guided endoscopic procedure, comprising: presenting, on a display, a 2D sectional image showing a region of interest from a preoperative CT scan; defining a control point on the 2D sectional image within a patient's body lumen responsive to a first user input; centering the control point; adjusting a viewing angle about the control point to show a longitudinal section of the body lumen responsive to a second user input; identifying a second point on a planned path within the body lumen responsive to a third user input; extending a planned path connecting the control point and the second point; redefining the second point as a new control point; and repeating the presenting adjusting, identifying, extending, and the redefining steps until the planned path reaches a procedure starting point within the patient's body.
US10531810B2 Detection of atrial fibrillation causes
This document provides devices and methods for the treatment of heart conditions. For example, this document provides devices and methods for detecting heart rotors such that effectively targeted cardiac fibrillation treatments can be provided.
US10531805B2 Biophysical sensing systems and methods using non-contact electric field detectors
Aspects are generally directed to systems and methods that integrate contactless electric field detectors to measure biophysical signals generated by a body. In one example, a biophysical sensing system includes a sensing assembly including an array of contactless electric field detectors, each of the contactless electric field detectors being configured to sense a corresponding component of an electric field generated by a body, a control system to receive sensor data indicative of the components of the electric field sensed by each of the contactless electric field detectors, the control system being configured to generate an estimate of the electric field based on the sensor data, and a feedback system coupled to at least the control system, the feedback system including at least one feedback interface, the feedback system being configured to operate the feedback interface to provide feedback based on the estimate of the electric field.
US10531802B2 Vital sign monitoring apparatuses and methods of using same
A system for vital sign measuring of a patient, comprising: a first sensor removably attachable with a first body portion of the patient and configured to measure, when in operable position, a vital sign of the patient; at least one additional sensor removably attachable with a second body portion of the patient and configured to measure, when in operable position, a vital sign of the patient; and a processor configured to provide data descriptive of a level of correspondence between measurements of the vital signs provided by the first sensor and the at least one additional sensor.
US10531799B2 Intravenous access device detecting intravenous infiltration and in-vein placement
Aspects of the invention relates to systems and methods for monitoring an intravenous (IV) line functionality of an IV device. In one embodiment, the system includes an IV catheter to be inserted into the vein of the living subject, at least one pressure sensor in fluid communication with the IV catheter to acquire peripheral venous signals; and a processing device. The processing device receives the peripheral venous signals from the pressure sensor, performs a spectral analysis on the peripheral venous signals to obtain a peripheral venous pressure frequency spectrum, and then performs a statistical analysis on amplitudes of peaks of the peripheral venous pressure frequency spectrum to determine an IV line functionality of the IV catheter in real time. When the IV line functionality indicates IV infiltration, the processing device may control the fluid controlling device to stop the fluid flow from the fluid source to the IV catheter.
US10531796B2 Method and system for wirelessly and passively measuring temperature and devices forming the system
The present disclosure provides a method and a system for wirelessly and passively measuring temperature and devices forming the system. The method includes: receiving an energy feedback radio frequency (RF) signal by a temperature measuring end; converting the energy feedback RF signal into electric energy and storing the electric energy; and starting the temperature measuring end after obtaining the electric energy, and transmitting a RF signal under the current temperature to a terminal, and calculating the current temperature through the terminal. The method, the system and the devices forming the system provided in the present disclosure are capable of activating the crystal oscillator or the ceramic oscillator wirelessly and passively, therefore, the method, the system and the devices can be used to wirelessly and passively measure temperature, which is convenient.
US10531794B1 Photorefractive flash device and system
The current invention is a Photorefractive Flash Device and System. It is a device that can be clipped to any portable computing device to illuminate the pupil in a way, that allows a proper pupillary reflex. On the backside of the device is a photoreceptor, on the frontside—facing the persons eyes are LEDs, centered around an opening where the lens of the camera looks through. A smartphone-app triggers the flashlight of the camera. The photoreceptor of the device senses this flash and triggers the six LEDs to flash sequentially within 200 milliseconds. 200 milliseconds is the time, the pupil needs to react. By staying under this 200 milliseconds, it can achieve high-quality pictures of the pupillary reflection, before the pupil contracts.
US10531792B2 Intubation device
An intubation device for use in an endotracheal intubation procedure, the intubation device including: a laryngoscope blade having a tip and a base; a handle attached to the base of the blade for allowing the intubation device to be held in a hand of a user; a channel for receiving an endotracheal tube, the channel including a blade channel portion extending along the blade substantially from the tip to the base and including an outlet proximate to the tip for allowing a distal end of the endotracheal tube to be advanced from the outlet and a handle channel portion extending partially along the handle from the blade channel portion; and a tube movement mechanism in the handle for moving the endotracheal tube through the channel to thereby advance the endotracheal tube, the tube movement mechanism including a thumb interface for allowing the user to operate the tube movement mechanism using a thumb of the hand that is holding the intubation device, to thereby allow the user to hold the intubation device and advance the endotracheal tube in an endotracheal intubation procedure using a single hand.
US10531789B2 Light-source device
A light-source device includes: two long-wavelength light sources that emit red long-wavelength light beams (LWLs); a broadband light source that emits a green broadband light beam (BL); and a multiplexing portion that multiplexes a wavelength region greater than a first predetermined wavelength λ1 of one of the LWLs having a longer peak wavelength and a wavelength region equal to or less than λ1 of the other LWL having a shorter peak wavelength, and that multiplexes a wavelength region greater than a second predetermined wavelength λ2 of the other LWL and a wavelength region equal to or less than λ2 of the BL, wherein intensities of the LWLs at λ1 are equal to or greater than 10% of the peak intensities thereof and intensities of the other LWL and the BL at λ2 are equal to or greater than 10% of the peak intensities thereof.
US10531786B2 In vivo capsule device with electrodes
A capsule endoscopic device with movement control is disclosed. The capsule endoscopic device comprises a capsule housing, one or more electrodes disposed fixedly through the capsule housing, a signal generation/signal driver unit, an interface circuit and a switch module. The electrodes apply electrical stimulus to living body tissue in a patient's gastrointestinal track. The signal generation/signal driver unit generates the electrical stimulus for the electrodes. The switch module is coupled to the electrodes, the signal generation/signal driver unit and the interface circuit. Furthermore, the switch module is configured to connect the electrodes to the signal generation/signal driver unit or the interface circuit depending on an operation mode. The switch module, the signal generation/signal driver unit and the interface circuit are inside the capsule housing.
US10531783B1 Movable cutlery basket
A dishwasher rack includes a frame and a support rail disposed along sides of the frame. A plurality of cutlery baskets are coupled to the rail. Each cutlery basket is movable from a respective first location on the rail to a respective second location on the rail. The cutlery baskets may be removable to enable a user to adjust a ratio of cutlery storage area to crockery storage area as desired. Also, the cutlery baskets may be arranged to revolve along a perimeter of the rack so that a user can load empty baskets at the same location.
US10531781B2 Dishwasher with discretely directable tubular spray elements
A method and dishwasher utilize one or more tubular spray elements that are both rotatable about longitudinal axes thereof and discretely directable by one or more tubular spray element drives between a plurality of rotational positions about the longitudinal axes thereof. Thus, through the provision of discretely directable tubular spray elements, fluid such as wash fluid and/or pressurized air may be focused in a wash tub, in many cases providing more efficient resource usage in the dishwasher.
US10531778B2 Vacuum cleaner
A vacuum cleaner includes a cleaner body; a suction unit connected with the cleaner body, sucking dust and air, guiding the sucked dust and air to the cleaner body, and having a handle; a moving unit including a wheel and a motor for driving the wheel to automatically move the cleaner body; and a clutch unit connecting the motor and the wheel or releasing the connection of the motor and the wheel according to an operational state of the cleaner body. The clutch unit includes a sun gear connected with the motor, a ring gear connected with the wheel, a plurality of fixed planetary gears disposed to be spaced apart each other between the sun gear and the ring gear, and a moving planetary gear which may transmit a rotational force transmitted to the sun gear to one gear of the plurality of fixed planetary gears.
US10531773B2 Hand-held vacuum cleaner
A hand-held vacuum cleaner (100) is provides, including a housing (1) and a floor brush (200), the housing (1) is provided with an air inlet (111) and an air blowing vent (121), the air blowing vent (121) is disposed adjacent to the air inlet (111); the floor brush (200) is provided with a floor brush inlet (201), a floor brush outlet (203) and a floor brush opening (202), the floor brush inlet (201) is in communication with the air blowing vent (121), the floor brush outlet (203) is in communication with the air inlet (111), the floor brush opening (202) is located at a side of the floor brush (200) away from the housing (1), and an airflow blowing from the air blowing vent (121) first flows to the floor brush opening (202) through the floor brush inlet (201), and then flows to the air inlet (111) through the floor brush outlet (203).
US10531768B1 Food chopper
A food chopper having a handle, a first side cutting blade, a second side cutting blade and a central cutting blade. The first side cutting blade is attached to the handle. The second side cutting blade is attached to the handle in a spaced-apart relationship with respect to the first side cutting blade. The central cutting blade is operably attached to the handle intermediate the first side cutting blade and the second side cutting blade for movement between an extended configuration and a retracted configuration. The central cutting blade is biased to the extended configuration. At least one of the first side cutting blade and the second side cutting blade is curved.
US10531765B2 Kamado style cooker
A cast iron kamado style cooker includes a cast iron frustoconical pot and a semi-spherical cast iron lid. Both the lid and the pot are configured with integrally-formed circumferential band surrounding areas of each that comprise the greatest diameter and are pivotally connected to each other so that the lid may be rotated away from the pot. The cooker also includes a lift assist mechanism operative to impart a force to contribute to raising the cast iron lid.
US10531764B2 Insulated serving dish
An insulated serving dish. The insulated serving dish includes a housing having an interior volume and a container disposed within the housing interior volume such that a channel is formed between the housing sidewalls and container sidewalls. The container receives ice therein for maintaining food at a cold temperature during serving. A support tray is removably received by the container volume above the ice stored therein. A plurality of food trays are then supported by the support tray, such that the interior volume of the food tray is positioned within the interior volume of the container. A lid that selectively encloses the container volume has a lower edge that occupies that channel between the container sidewall and housing sidewalls. The lid may be pivotally affixed to the housing and container such that it may be rotated between a closed position and an open position.
US10531755B1 Drink holder mounting structure for attaching to various tubular objects
A clamp body includes a first clamping member and a clamping seat that are integrally formed together, a pivot hole formed in the clamping seat, and a second clamping member pivotally connected to the pivot hole. Also included are an elongated through hole formed in the first clamping member, a circular arc wall extending from the elongated through hole and gradually shallowing from a depth, a position-limiting axle between inside wall surfaces of the second clamping member, a tightness adjusting assembly including a rounded-head pushing rod, and a rotation assembly for coupling the clamp body and the holder. As such, the clamp body that has one arm to fix and one arm to move could improve stability of clamping. The arrangement of the elongated through hole and the circular arc wall gradually shallowing from a depth is used to reduce a size of the tightness adjusting assembly projecting to outside.
US10531754B2 Modified folding disposable coffee cup sleeve
A disposable insulator for a cup having a sleeve including an insulating material to provide thermal insulation to the exterior of the cup, the sleeve having at least one finger pad made of the insulating material having a bottom edge, the finger pad being separable from the remainder of the sleeve and moveable from a first position to a second position, in the first position, the bottom edge of the finger pad being proximate to the bottom edge of the sleeve, and, in the second position the finger pad being foldable relative to the sleeve with the bottom edge of the finger pad positionable proximate to the top edge of the sleeve.